## Thu Oct 17 12:27:17 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/PYH2_bin.67.fa -m mmseqs --itype genome -o PYH2_bin.67 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/PYH2_bin.67 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
PYH2_k127_1018042_0	420324.KI912043_gene4011	6.451e-224	730.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,1JR57@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1
PYH2_k127_1027804_19	987059.RBXJA2T_08645	2.104e-41	158.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VJ0X@28216|Betaproteobacteria,1KKG9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
PYH2_k127_1027804_5	887062.HGR_13459	3.342e-204	667.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2VJIT@28216|Betaproteobacteria,4AC6D@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	gabT	-	2.6.1.19,2.6.1.22,2.6.1.76	ko:K00823,ko:K00836,ko:K07250	ko00250,ko00260,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,ko01210,ko01230,map00250,map00260,map00280,map00410,map00640,map00650,map01100,map01120,map01210,map01230	M00027,M00033	R00908,R01648,R04188,R06977	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_1027804_1	420662.Mpe_A1909	4.965e-261	813.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHNV@28216|Betaproteobacteria,1KJBV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	puuC	-	1.2.1.54,1.2.1.8,1.2.1.99	ko:K00130,ko:K09472,ko:K12254	ko00260,ko00330,ko01100,map00260,map00330,map01100	M00136,M00555	R02549,R02565,R02566,R03177,R07417,R07418	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_1027804_9	864051.BurJ1DRAFT_2658	3.197e-192	621.0	COG3637@1|root,COG3637@2|Bacteria,1N1WQ@1224|Proteobacteria,2VMY3@28216|Betaproteobacteria,1KJWH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	DUF3138
PYH2_k127_1027804_13	420662.Mpe_A1906	1.425e-132	436.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2VHYY@28216|Betaproteobacteria,1KJVC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	transport system permease	potI	-	-	ko:K11074	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
PYH2_k127_1027804_10	420662.Mpe_A1905	4.115e-161	511.0	COG1176@1|root,COG1176@2|Bacteria,1MVGM@1224|Proteobacteria,2VHYC@28216|Betaproteobacteria,1KJGM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	transport system permease	potH	-	-	ko:K11075	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	BPD_transp_1
PYH2_k127_1027804_8	864051.BurJ1DRAFT_2655	9.841e-193	610.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,1KJFE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	-	ko:K11076	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	ABC_tran,TOBE_2
PYH2_k127_1027804_6	420662.Mpe_A1903	2.504e-201	632.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJDV@28216|Betaproteobacteria,1KIYX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Required for the activity of the bacterial periplasmic transport system of putrescine	potF	-	-	ko:K11073	ko02010,map02010	M00300	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.2	-	-	SBP_bac_8
PYH2_k127_1027804_4	987059.RBXJA2T_08610	3.386e-252	795.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VHST@28216|Betaproteobacteria,1KIYT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.113	ko:K12256	ko00330,ko01100,map00330,map01100	-	R08714	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_1027804_0	420662.Mpe_A1901	3.656e-280	863.0	COG0174@1|root,COG0174@2|Bacteria,1MU6V@1224|Proteobacteria,2VJHJ@28216|Betaproteobacteria,1KJKE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	glutamine synthetase	puuA2	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
PYH2_k127_1027804_14	864051.BurJ1DRAFT_2651	6.957e-109	364.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VQGX@28216|Betaproteobacteria,1KJ70@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase C26	puuD	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
PYH2_k127_1027804_7	420662.Mpe_A1899	8.176e-200	631.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2VIFN@28216|Betaproteobacteria,1KJQY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	ordL	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
PYH2_k127_1027804_3	864051.BurJ1DRAFT_2649	1.831e-252	782.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,1KITC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_1027804_16	864051.BurJ1DRAFT_2648	4.239e-73	250.0	COG1522@1|root,COG1522@2|Bacteria,1RI7R@1224|Proteobacteria,2VQK9@28216|Betaproteobacteria,1KKS9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
PYH2_k127_1027804_18	983917.RGE_26200	2.377e-56	202.0	COG3945@1|root,COG3945@2|Bacteria,1RIAD@1224|Proteobacteria,2VT7C@28216|Betaproteobacteria,1KM41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
PYH2_k127_1027804_11	420662.Mpe_A1890	2.293e-159	514.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJHD@28216|Betaproteobacteria,1KK1M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
PYH2_k127_1027804_15	983917.RGE_26180	7.774e-76	261.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria,1KMMW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
PYH2_k127_1027804_2	864051.BurJ1DRAFT_2642	1.447e-259	804.0	COG2224@1|root,COG2224@2|Bacteria,1MWIF@1224|Proteobacteria,2VHWS@28216|Betaproteobacteria,1KJQD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Isocitrate lyase	aceA	-	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
PYH2_k127_1027804_22	1234364.AMSF01000068_gene2148	1.067e-29	128.0	COG3009@1|root,COG3009@2|Bacteria,1RII3@1224|Proteobacteria,1S7SN@1236|Gammaproteobacteria,1X7BX@135614|Xanthomonadales	135614|Xanthomonadales	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K09857	-	-	-	-	ko00000	-	-	-	ABC_trans_aux
PYH2_k127_1027804_12	1163407.UU7_01327	3.911e-148	488.0	COG1463@1|root,COG3008@1|root,COG1463@2|Bacteria,COG3008@2|Bacteria,1MU1T@1224|Proteobacteria,1RN89@1236|Gammaproteobacteria,1X48N@135614|Xanthomonadales	135614|Xanthomonadales	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
PYH2_k127_1027804_17	1235457.C404_11795	3.316e-62	221.0	COG2995@1|root,COG2995@2|Bacteria,1MWG1@1224|Proteobacteria,2VMXT@28216|Betaproteobacteria,1K33I@119060|Burkholderiaceae	28216|Betaproteobacteria	S	paraquat-inducible protein A	pqiA	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
PYH2_k127_1027804_20	1123261.AXDW01000014_gene3222	4.849e-41	160.0	COG2995@1|root,COG2995@2|Bacteria,1RAQ9@1224|Proteobacteria,1SBDT@1236|Gammaproteobacteria,1X6U5@135614|Xanthomonadales	135614|Xanthomonadales	S	paraquat-inducible protein A	-	-	-	ko:K03808	-	-	-	-	ko00000	-	-	-	PqiA
PYH2_k127_1027804_21	1411123.JQNH01000001_gene2362	1.252e-40	160.0	COG0664@1|root,COG0664@2|Bacteria,1Q93V@1224|Proteobacteria,2TTEY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	cyclic nucleotide-binding	MA20_09210	-	-	-	-	-	-	-	-	-	-	-	Imp-YgjV,cNMP_binding
PYH2_k127_1027804_23	113395.AXAI01000021_gene3453	1.084e-22	108.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_1029660_5	1538295.JY96_07935	2.475e-11	65.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KJ12@119065|unclassified Burkholderiales	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	rhlE2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
PYH2_k127_1029660_1	1286631.X805_21820	1.264e-81	281.0	COG0313@1|root,COG0313@2|Bacteria,1RARW@1224|Proteobacteria,2VQ34@28216|Betaproteobacteria,1KJZF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase	rsmI_2	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
PYH2_k127_1029660_2	543728.Vapar_1385	2.754e-75	259.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,4ABNK@80864|Comamonadaceae	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
PYH2_k127_1029660_3	983917.RGE_41160	1.486e-40	157.0	COG1399@1|root,COG1399@2|Bacteria,1PGKW@1224|Proteobacteria,2VUIG@28216|Betaproteobacteria,1KM8F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
PYH2_k127_1029660_4	1538295.JY96_02515	1.491e-30	120.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,1KMN3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
PYH2_k127_1029660_0	1265502.KB905932_gene1840	3.635e-178	565.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,4A9V1@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
PYH2_k127_1035898_2	648757.Rvan_0036	2.356e-07	53.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,2UNSE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH2_k127_1035898_1	1232410.KI421421_gene3270	3.404e-177	565.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
PYH2_k127_1035898_0	85643.Tmz1t_2950	3.792e-211	669.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2W3EH@28216|Betaproteobacteria,2KZ1E@206389|Rhodocyclales	206389|Rhodocyclales	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
PYH2_k127_1041912_5	365046.Rta_00810	2.177e-25	108.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VN65@28216|Betaproteobacteria,4A9Q0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
PYH2_k127_1041912_1	379066.GAU_1050	1.402e-105	353.0	COG2888@1|root,COG2888@2|Bacteria,1ZUHM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1041912_2	420662.Mpe_A0135	4.764e-101	336.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2VQH1@28216|Betaproteobacteria,1KM67@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	creB	-	-	ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH2_k127_1041912_0	365046.Rta_00600	3.177e-183	585.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2VH7Q@28216|Betaproteobacteria,4AB4V@80864|Comamonadaceae	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	creC	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_3
PYH2_k127_1041912_3	1379270.AUXF01000001_gene2548	1.072e-29	124.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria	2|Bacteria	QT	Acyl-homoserine-lactone synthase	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AIRS,Acetyltransf_10,Acetyltransf_5,Aminotran_5
PYH2_k127_1041912_4	395495.Lcho_0010	1.611e-27	113.0	29DRS@1|root,300PM@2|Bacteria,1RF8B@1224|Proteobacteria,2VR3X@28216|Betaproteobacteria,1KNPH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1051563_1	887062.HGR_15539	3.577e-34	139.0	2DF7Q@1|root,33391@2|Bacteria,1NB8A@1224|Proteobacteria,2VWDS@28216|Betaproteobacteria,4AFN9@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1051563_0	395495.Lcho_1661	2.171e-58	209.0	COG0778@1|root,COG0778@2|Bacteria,1PKUV@1224|Proteobacteria,2VSFP@28216|Betaproteobacteria,1KM3R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	nitroreductase	aoxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
PYH2_k127_1051563_2	1038922.PflQ2_2311	1.035e-30	126.0	COG0730@1|root,COG0730@2|Bacteria,1MVYH@1224|Proteobacteria,1RS3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH2_k127_1057157_1	861299.J421_3809	4.885e-42	157.0	COG0058@1|root,COG0058@2|Bacteria,1ZSZ3@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
PYH2_k127_1057157_0	557598.LHK_01273	1.4e-90	321.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
PYH2_k127_1064721_4	1996.JOFO01000021_gene2516	7.035e-05	49.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria,4EGGN@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
PYH2_k127_1064721_1	1265502.KB905970_gene1300	8.439e-104	342.0	COG0524@1|root,COG0524@2|Bacteria,1MVG2@1224|Proteobacteria,2VKA3@28216|Betaproteobacteria,4ACV6@80864|Comamonadaceae	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	kdgK	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
PYH2_k127_1064721_2	388051.AUFE01000012_gene2886	1.284e-39	152.0	2CNK3@1|root,32SH9@2|Bacteria,1N02U@1224|Proteobacteria,2VUNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
PYH2_k127_1064721_3	420662.Mpe_A3050	3.897e-32	143.0	2E35S@1|root,32Y5P@2|Bacteria,1N6WS@1224|Proteobacteria,2VV11@28216|Betaproteobacteria,1KMDZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
PYH2_k127_1064721_0	78245.Xaut_3224	1.197e-153	496.0	COG1249@1|root,COG1249@2|Bacteria,1MU2Z@1224|Proteobacteria,2TQS7@28211|Alphaproteobacteria,3EYAQ@335928|Xanthobacteraceae	28211|Alphaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	gor	GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700	1.8.1.7	ko:K00383	ko00480,ko04918,map00480,map04918	-	R00094,R00115	RC00011	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
PYH2_k127_1103561_1	420662.Mpe_A0549	9.271e-39	149.0	2ETEI@1|root,33KYE@2|Bacteria,1NJKD@1224|Proteobacteria,2W43N@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1103561_2	983917.RGE_04870	1.156e-21	96.0	2EITT@1|root,33CJ3@2|Bacteria,1NH36@1224|Proteobacteria,2VXT6@28216|Betaproteobacteria,1KMU3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
PYH2_k127_1103561_0	420662.Mpe_A0551	5.268e-149	481.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,1KJUW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
PYH2_k127_1103561_3	634177.GLX_11130	3.576e-05	52.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2TR0A@28211|Alphaproteobacteria,2JPRF@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
PYH2_k127_1104224_0	631454.N177_2724	2.831e-166	538.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,1JN4S@119043|Rhodobiaceae	28211|Alphaproteobacteria	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PYH2_k127_1109090_6	1265502.KB905964_gene1382	3.106e-121	392.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,4A9RX@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM AAA ATPase central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
PYH2_k127_1109090_2	420662.Mpe_A1123	4.592e-174	550.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,1KJNJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_1109090_0	864051.BurJ1DRAFT_1701	2.963e-185	584.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VH43@28216|Betaproteobacteria,1KJ88@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_1109090_3	420662.Mpe_A1125	7.564e-146	464.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,1KK0Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_1109090_5	420662.Mpe_A1126	7.358e-124	399.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,1KJ0T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_1109090_7	1123393.KB891316_gene1406	3.057e-90	308.0	COG3409@1|root,COG3409@2|Bacteria,1N4WW@1224|Proteobacteria,2VH9D@28216|Betaproteobacteria,1KT3A@119069|Hydrogenophilales	119069|Hydrogenophilales	M	PFAM Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1109090_4	864051.BurJ1DRAFT_1705	7.159e-138	445.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VK73@28216|Betaproteobacteria,1KN0D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_1109090_1	420662.Mpe_A1127	2.366e-184	585.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,1KK9J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
PYH2_k127_1109090_8	365044.Pnap_3203	1.535e-16	93.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,4A9TJ@80864|Comamonadaceae	28216|Betaproteobacteria	GM	Nad-dependent epimerase dehydratase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
PYH2_k127_1111020_2	1100720.ALKN01000007_gene3065	8.534e-39	150.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VNQX@28216|Betaproteobacteria,4AC0P@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_1111020_0	1100720.ALKN01000007_gene3066	7.552e-175	561.0	COG3185@1|root,COG3185@2|Bacteria,1MVR0@1224|Proteobacteria,2VJHM@28216|Betaproteobacteria,4AA6W@80864|Comamonadaceae	28216|Betaproteobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
PYH2_k127_1111020_3	1100720.ALKN01000007_gene3067	1.469e-26	126.0	2CIU6@1|root,32S8H@2|Bacteria,1MZTN@1224|Proteobacteria,2VU36@28216|Betaproteobacteria,4AJGU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1111020_1	1192034.CAP_1692	1.569e-67	240.0	COG1024@1|root,COG1024@2|Bacteria,1NDT7@1224|Proteobacteria,42PZ0@68525|delta/epsilon subdivisions,2WM9Y@28221|Deltaproteobacteria,2YUF3@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH2_k127_1115073_4	864051.BurJ1DRAFT_0194	1.283e-65	229.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2VRJE@28216|Betaproteobacteria,1KM5E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
PYH2_k127_1115073_2	266265.Bxe_A2144	5.515e-115	381.0	COG1319@1|root,COG1319@2|Bacteria,1MUDB@1224|Proteobacteria,2VSFQ@28216|Betaproteobacteria,1K13T@119060|Burkholderiaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH2_k127_1115073_3	266265.Bxe_A2145	9.624e-77	259.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ75@28216|Betaproteobacteria,1K322@119060|Burkholderiaceae	28216|Betaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_1115073_0	196367.JNFG01000011_gene6092	0.0	1186.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,1K4XH@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH2_k127_1115073_5	266265.Bxe_A2147	2.486e-63	223.0	COG3427@1|root,COG3427@2|Bacteria,1N4EQ@1224|Proteobacteria,2W4Q9@28216|Betaproteobacteria,1K52T@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Carbon monoxide dehydrogenase subunit G (CoxG)	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
PYH2_k127_1115073_1	196367.JNFG01000011_gene6090	2.014e-127	415.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2VIJR@28216|Betaproteobacteria,1K34U@119060|Burkholderiaceae	28216|Betaproteobacteria	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
PYH2_k127_1115073_6	1121127.JAFA01000006_gene5459	1.601e-23	106.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2VNH5@28216|Betaproteobacteria,1K1YF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
PYH2_k127_113077_1	864051.BurJ1DRAFT_2041	7.595e-204	648.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,1KK4D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
PYH2_k127_113077_5	864051.BurJ1DRAFT_2040	9.291e-74	254.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2W9FK@28216|Betaproteobacteria,1KKMT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
PYH2_k127_113077_2	395495.Lcho_1553	2.649e-178	569.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PD5J@1224|Proteobacteria,2W9PK@28216|Betaproteobacteria,1KMZ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
PYH2_k127_113077_3	395495.Lcho_1552	7.324e-98	334.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,1KKAY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
PYH2_k127_113077_6	420662.Mpe_A1209	3.427e-46	171.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,1KM3E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
PYH2_k127_113077_4	420662.Mpe_A1210	1.594e-81	277.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,1KKN4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Periplasmic protein thiol	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
PYH2_k127_113077_0	420662.Mpe_A1211	0.0	1038.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,1KIYF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	cytochrome C	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
PYH2_k127_113077_7	864051.BurJ1DRAFT_4600	3.447e-09	65.0	COG0810@1|root,COG3064@1|root,COG0810@2|Bacteria,COG3064@2|Bacteria,1REKC@1224|Proteobacteria,2VRYT@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2
PYH2_k127_1132160_0	1265502.KB905938_gene2482	3.366e-172	542.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,4AC27@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
PYH2_k127_1132160_5	1265502.KB905938_gene2483	5.643e-86	292.0	COG1011@1|root,COG1011@2|Bacteria,1PHPQ@1224|Proteobacteria,2VNRS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	ssm	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
PYH2_k127_1132160_4	987059.RBXJA2T_06885	1.776e-90	312.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,1KK77@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
PYH2_k127_1132160_13	864051.BurJ1DRAFT_1216	1.608e-05	50.0	COG1407@1|root,COG1407@2|Bacteria,1RC5G@1224|Proteobacteria,2VRFD@28216|Betaproteobacteria,1KKYR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM metallophosphoesterase	-	-	-	ko:K06953	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
PYH2_k127_1132160_2	987059.RBXJA2T_06895	1.653e-143	460.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,1KJNB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
PYH2_k127_1132160_8	864051.BurJ1DRAFT_1218	5.719e-67	235.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,1KKVF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
PYH2_k127_1132160_6	987059.RBXJA2T_06905	1.163e-68	234.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,1KKTY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
PYH2_k127_1132160_10	987059.RBXJA2T_06910	1.2e-44	169.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,1KM5H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
PYH2_k127_1132160_11	1458427.BAWN01000015_gene1037	2.342e-34	141.0	COG3671@1|root,COG3671@2|Bacteria,1MZMW@1224|Proteobacteria,2WG1H@28216|Betaproteobacteria	28216|Betaproteobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
PYH2_k127_1132160_9	987059.RBXJA2T_06920	1.434e-60	210.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,1KM2P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
PYH2_k127_1132160_12	420662.Mpe_A0841	5.141e-28	114.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,1KMNQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
PYH2_k127_1132160_7	420662.Mpe_A0842	4.918e-67	232.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,1KKZA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
PYH2_k127_1132160_3	420662.Mpe_A0843	9.7e-128	421.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,1KJ6N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
PYH2_k127_1132160_1	1265502.KB905938_gene2455	1.855e-146	469.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,4AA2V@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase S1 and S6, chymotrypsin Hap	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
PYH2_k127_1142849_0	358220.C380_03360	6.048e-164	522.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,4AAB0@80864|Comamonadaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB2	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH2_k127_1142849_4	1502851.FG93_04809	5.651e-42	165.0	COG2984@1|root,COG2984@2|Bacteria,1R7C2@1224|Proteobacteria,2TZKG@28211|Alphaproteobacteria,3JXR0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
PYH2_k127_1142849_5	338969.Rfer_2754	2.182e-23	102.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,4AAB0@80864|Comamonadaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB2	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH2_k127_1142849_1	1123377.AUIV01000012_gene721	1.443e-116	386.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria,1XAEU@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PYH2_k127_1142849_3	404589.Anae109_2915	7.244e-56	201.0	COG2010@1|root,COG2010@2|Bacteria,1RBTK@1224|Proteobacteria,43AHK@68525|delta/epsilon subdivisions,2X5XT@28221|Deltaproteobacteria,2YVZ8@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1142849_2	1116472.MGMO_55c00010	7.575e-62	228.0	COG3568@1|root,COG3568@2|Bacteria,1N29G@1224|Proteobacteria	1224|Proteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
PYH2_k127_1155293_4	296591.Bpro_0177	1.718e-41	153.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,4AAQW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_1155293_8	1157708.KB907458_gene1855	9.952e-17	87.0	COG2823@1|root,COG2823@2|Bacteria,1N4W2@1224|Proteobacteria,2VV7P@28216|Betaproteobacteria,4AF5E@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON,EF-hand_5
PYH2_k127_1155293_3	296591.Bpro_0177	9.965e-94	314.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,4AAQW@80864|Comamonadaceae	28216|Betaproteobacteria	K	Crp Fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_1155293_2	296591.Bpro_0178	6.174e-99	344.0	COG0664@1|root,COG0664@2|Bacteria,1RAF3@1224|Proteobacteria,2VQIC@28216|Betaproteobacteria,4AE0D@80864|Comamonadaceae	28216|Betaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
PYH2_k127_1155293_0	338969.Rfer_0020	8.047e-167	531.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,4AAH8@80864|Comamonadaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PYH2_k127_1155293_6	204773.HEAR0765	6.532e-28	114.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1155293_9	290317.Cpha266_1360	2.691e-16	80.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1155293_5	338969.Rfer_2343	1.013e-31	136.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VUHT@28216|Betaproteobacteria,4AF5X@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
PYH2_k127_1155293_1	338969.Rfer_1963	1.195e-107	353.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,2VJ27@28216|Betaproteobacteria,4AAAZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
PYH2_k127_1158041_8	1120985.AUMI01000017_gene2729	5.829e-52	190.0	COG2930@1|root,COG2930@2|Bacteria,1VBSP@1239|Firmicutes,4H54G@909932|Negativicutes	909932|Negativicutes	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
PYH2_k127_1158041_2	420662.Mpe_A0371	4.744e-246	764.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VHST@28216|Betaproteobacteria,1KIYT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
PYH2_k127_1158041_9	420662.Mpe_A0370	1.218e-32	135.0	arCOG10157@1|root,31I3P@2|Bacteria,1MYQ9@1224|Proteobacteria	1224|Proteobacteria	S	ethyl tert-butyl ether degradation	-	-	-	-	-	-	-	-	-	-	-	-	EthD,MmlI
PYH2_k127_1158041_5	420662.Mpe_A0369	8.59e-85	288.0	28I63@1|root,2Z897@2|Bacteria,1N3VY@1224|Proteobacteria,2VJCE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Amino acid synthesis	-	-	-	-	-	-	-	-	-	-	-	-	AA_synth
PYH2_k127_1158041_7	234267.Acid_6399	8.94e-55	205.0	COG0265@1|root,COG0265@2|Bacteria,3Y7VS@57723|Acidobacteria	57723|Acidobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
PYH2_k127_1158041_10	926550.CLDAP_35250	9.536e-14	82.0	COG2197@1|root,COG2197@2|Bacteria,2G73R@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PYH2_k127_1158041_1	1218084.BBJK01000037_gene3487	3.002e-258	806.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VZ6E@28216|Betaproteobacteria,1K0K8@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
PYH2_k127_1158041_3	1056512.D515_02334	3.987e-220	697.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,1RMD2@1236|Gammaproteobacteria,1XU4R@135623|Vibrionales	135623|Vibrionales	C	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
PYH2_k127_1158041_4	1191460.F959_00406	7.679e-183	586.0	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,3NJP9@468|Moraxellaceae	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	calB	-	1.2.1.68	ko:K00154	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
PYH2_k127_1158041_0	614083.AWQR01000005_gene1247	5e-324	1010.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2VJ5N@28216|Betaproteobacteria,4AD5B@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Alkyl sulfatase C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,GMC_oxred_C,GMC_oxred_N,Lactamase_B
PYH2_k127_1158041_6	420662.Mpe_A1216	6.974e-70	249.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,1KM0J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
PYH2_k127_1164945_6	1123367.C666_16925	1.696e-63	219.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2VJ4U@28216|Betaproteobacteria,2KXU0@206389|Rhodocyclales	206389|Rhodocyclales	U	. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. PFam MotA TolQ ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
PYH2_k127_1164945_8	395495.Lcho_3233	1.068e-53	195.0	COG0848@1|root,COG0848@2|Bacteria,1RH4U@1224|Proteobacteria,2VSF4@28216|Betaproteobacteria,1KM48@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD1	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
PYH2_k127_1164945_7	395495.Lcho_3232	3.385e-56	199.0	COG0848@1|root,COG0848@2|Bacteria,1RHDF@1224|Proteobacteria,2VT16@28216|Betaproteobacteria,1KM2K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
PYH2_k127_1164945_3	395495.Lcho_3231	1.972e-100	348.0	COG0457@1|root,COG0457@2|Bacteria,1Q7UR@1224|Proteobacteria,2VKBS@28216|Betaproteobacteria,1KJ62@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
PYH2_k127_1164945_0	1265502.KB905930_gene1440	3.265e-140	448.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2VHU8@28216|Betaproteobacteria,4ABDR@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	fabG3	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
PYH2_k127_1164945_1	1265502.KB905930_gene1454	2.182e-110	360.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,4AAQG@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
PYH2_k127_1164945_2	420662.Mpe_A2487	9.739e-102	339.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,1KJA1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
PYH2_k127_1164945_10	1265502.KB905930_gene1456	2.626e-20	92.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,4AFCV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0434 family	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
PYH2_k127_1164945_4	864051.BurJ1DRAFT_3511	2.589e-98	331.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,1KJ4E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
PYH2_k127_1164945_9	864051.BurJ1DRAFT_3510	5.151e-50	185.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,1KM7P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
PYH2_k127_1164945_5	864051.BurJ1DRAFT_3509	1.428e-87	293.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,1KJMS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
PYH2_k127_1172752_6	397945.Aave_0712	0.0001254	46.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
PYH2_k127_1172752_5	1054213.HMPREF9946_02181	5.571e-05	47.0	COG1525@1|root,COG1525@2|Bacteria	2|Bacteria	L	nuclease	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
PYH2_k127_1172752_0	1265502.KB905971_gene1282	7.995e-320	998.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,4AA2T@80864|Comamonadaceae	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
PYH2_k127_1172752_4	987059.RBXJA2T_03329	9.005e-125	405.0	COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2WGMM@28216|Betaproteobacteria,1KPDQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
PYH2_k127_1172752_3	1286631.X805_08660	2.821e-126	407.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2VH6T@28216|Betaproteobacteria,1KKFF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	KR domain	bdhA	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
PYH2_k127_1172752_2	1265502.KB905971_gene1286	5.463e-142	454.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,2VI6B@28216|Betaproteobacteria,4A9UZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	ompR	-	-	ko:K02483,ko:K07659	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH2_k127_1172752_1	420662.Mpe_A1573	1.294e-219	689.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2VJ6W@28216|Betaproteobacteria,1KJSW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	risS	-	2.7.13.3	ko:K07638	ko02020,ko02026,map02020,map02026	M00445,M00742,M00743	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,RisS_PPD
PYH2_k127_1175296_8	76114.ebB88	9.221e-43	162.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,2VU9B@28216|Betaproteobacteria,2KX63@206389|Rhodocyclales	206389|Rhodocyclales	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
PYH2_k127_1175296_7	420662.Mpe_A2042	1.477e-58	209.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,2VRGX@28216|Betaproteobacteria,1KKUT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
PYH2_k127_1175296_2	338966.Ppro_0902	9.186e-185	620.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43UE7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,Response_reg
PYH2_k127_1175296_3	177437.HRM2_43250	1.781e-162	562.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2198@1|root,COG3850@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MHUJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,Hpt,Response_reg
PYH2_k127_1175296_9	1150469.RSPPHO_02636	3.569e-36	144.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2U9WD@28211|Alphaproteobacteria,2JTFS@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PYH2_k127_1175296_4	1121035.AUCH01000001_gene2109	3.226e-113	377.0	COG0596@1|root,COG0596@2|Bacteria,1MVVX@1224|Proteobacteria,2VH81@28216|Betaproteobacteria,2KVGE@206389|Rhodocyclales	28216|Betaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
PYH2_k127_1175296_11	395493.BegalDRAFT_1326	6.564e-16	87.0	2EJHR@1|root,33D8P@2|Bacteria,1NH0M@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1175296_6	395493.BegalDRAFT_1325	1.594e-94	344.0	COG0477@1|root,COG2814@2|Bacteria,1MXKN@1224|Proteobacteria,1S1A0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
PYH2_k127_1175296_5	1121035.AUCH01000001_gene2111	1.988e-104	353.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2VIC1@28216|Betaproteobacteria,2KXAY@206389|Rhodocyclales	206389|Rhodocyclales	S	transport system, periplasmic component	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_1175296_0	296591.Bpro_0273	2.512e-226	706.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VNZH@28216|Betaproteobacteria,4AC1K@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Dehydrogenase, E1 component	bkdA1	-	1.2.4.4	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,OxoDH_E1alpha_N
PYH2_k127_1175296_1	296591.Bpro_0274	2.28e-201	631.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,4ACZ7@80864|Comamonadaceae	28216|Betaproteobacteria	C	Transketolase, C-terminal domain	bkdA2	-	1.2.4.4	ko:K00167	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
PYH2_k127_1175296_10	1437824.BN940_11036	1.427e-32	130.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VKC1@28216|Betaproteobacteria,3T1KB@506|Alcaligenaceae	28216|Betaproteobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component and related enzymes	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH2_k127_120143_5	156889.Mmc1_1825	4.254e-23	110.0	2B79J@1|root,320CA@2|Bacteria,1N7TK@1224|Proteobacteria,2USKK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_120143_2	420662.Mpe_A3460	5.028e-97	325.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,1KJXI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the TrpC family	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
PYH2_k127_120143_1	864051.BurJ1DRAFT_0344	1.777e-178	563.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,1KJ9I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
PYH2_k127_120143_3	395495.Lcho_3878	3.588e-91	303.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,1KJPK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	Glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
PYH2_k127_120143_0	983917.RGE_03080	1.361e-270	839.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,1KIVZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
PYH2_k127_120143_4	595537.Varpa_2525	6.321e-43	159.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2VQNM@28216|Betaproteobacteria,4AEPY@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp_2	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
PYH2_k127_1210005_0	420662.Mpe_A2154	2.63e-192	612.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,1KJ3R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
PYH2_k127_1210005_1	1265502.KB905929_gene2275	3.489e-163	517.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,4A9ZT@80864|Comamonadaceae	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
PYH2_k127_1210005_2	420662.Mpe_A2156	6.777e-115	377.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,1KJQR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
PYH2_k127_1216520_0	420662.Mpe_A0326	2.586e-276	861.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,1KJSR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
PYH2_k127_1216520_10	688245.CtCNB1_0323	1.994e-24	105.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,4AF0H@80864|Comamonadaceae	28216|Betaproteobacteria	G	TIGRFAM phosphocarrier, HPr family	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PYH2_k127_1216520_6	1265502.KB905938_gene2511	5.273e-53	191.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,4AEDR@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	manX	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
PYH2_k127_1216520_2	1265502.KB905938_gene2512	7.996e-135	443.0	COG0477@1|root,COG2814@2|Bacteria,1QUY6@1224|Proteobacteria,2VNN5@28216|Betaproteobacteria,4AAMP@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_1216520_8	1265502.KB905938_gene2513	3.276e-37	148.0	2EBNJ@1|root,335NT@2|Bacteria,1N847@1224|Proteobacteria,2VW9H@28216|Betaproteobacteria,4AFB6@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1216520_1	987059.RBXJA2T_16217	1.928e-192	610.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,1KJ0W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
PYH2_k127_1216520_9	365044.Pnap_0222	5.078e-36	143.0	COG0596@1|root,COG0596@2|Bacteria,1R3U1@1224|Proteobacteria,2VNZR@28216|Betaproteobacteria,4A9XT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
PYH2_k127_1216520_13	526225.Gobs_3455	1.287e-10	74.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria,4EVT2@85013|Frankiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH2_k127_1216520_3	864051.BurJ1DRAFT_0464	2.234e-101	349.0	COG0784@1|root,COG0784@2|Bacteria,1R078@1224|Proteobacteria,2VN9R@28216|Betaproteobacteria,1KKGF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1216520_4	395495.Lcho_1717	8.85e-100	342.0	COG0189@1|root,COG0189@2|Bacteria,1QZYF@1224|Proteobacteria,2VUD3@28216|Betaproteobacteria,1KN14@119065|unclassified Burkholderiales	28216|Betaproteobacteria	HJ	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1216520_7	983917.RGE_44050	4.684e-44	163.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,1KKF4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
PYH2_k127_1216520_14	420662.Mpe_A0319	3.321e-10	64.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,1KKF4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
PYH2_k127_1216520_5	420662.Mpe_A0318	1.591e-58	214.0	COG0526@1|root,COG0526@2|Bacteria,1RDGI@1224|Proteobacteria,2VT2S@28216|Betaproteobacteria,1KKWR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
PYH2_k127_1254762_0	864051.BurJ1DRAFT_2483	0.0	1686.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KK7G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	bepE_2	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
PYH2_k127_1254762_1	864051.BurJ1DRAFT_2482	3.428e-131	426.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,2VKCK@28216|Betaproteobacteria,1KJT3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mdtA_2	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
PYH2_k127_1256890_0	864051.BurJ1DRAFT_2867	0.0	1176.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ1H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
PYH2_k127_1269850_0	381666.H16_B1914	1.431e-306	942.0	COG1024@1|root,COG1024@2|Bacteria,1N817@1224|Proteobacteria,2VKSK@28216|Betaproteobacteria,1K1EF@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Pfam Enoyl-CoA hydratase isomerase	boxC	-	4.1.2.44	ko:K15513	ko00362,map00362	-	R09556	RC03426	ko00000,ko00001,ko01000	-	-	-	ECH_1
PYH2_k127_1269850_1	864051.BurJ1DRAFT_0328	9.928e-291	904.0	COG3396@1|root,COG3396@2|Bacteria,1MXUK@1224|Proteobacteria,2VH89@28216|Betaproteobacteria,1KJY5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	benzoyl-CoA oxygenase	boxB	-	1.14.13.208	ko:K15512	ko00362,map00362	-	R09555	RC01739	ko00000,ko00001,ko01000	-	-	-	-
PYH2_k127_1269850_2	388051.AUFE01000002_gene435	5.117e-220	688.0	COG0369@1|root,COG1145@1|root,COG0369@2|Bacteria,COG1145@2|Bacteria,1NCKQ@1224|Proteobacteria,2VIZE@28216|Betaproteobacteria,1K05A@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Benzoyl-CoA oxygenase	boxA	-	1.14.13.208,1.18.1.2,1.19.1.1	ko:K00528,ko:K02641,ko:K15511	ko00195,ko00362,ko01100,map00195,map00362,map01100	-	R09555,R10159	RC01739	ko00000,ko00001,ko00194,ko01000	-	-	-	FAD_binding_6,Fer4,NAD_binding_1
PYH2_k127_1269850_3	1286631.X805_40590	2.305e-174	561.0	COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VK75@28216|Betaproteobacteria,1KKEB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	3-hydroxyacyl-CoA dehydrogenase domain protein	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
PYH2_k127_1269850_4	420662.Mpe_A0338	2.161e-38	147.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,1KK63@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	fdwB	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
PYH2_k127_1306092_5	1472716.KBK24_0105810	1.414e-65	229.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VIRU@28216|Betaproteobacteria,1K2JD@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.5.1.1,4.3.1.12	ko:K01750,ko:K19743	ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230	-	R00671,R01246,R01249,R02201,R02203	RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
PYH2_k127_1306092_0	1157708.KB907454_gene2959	7.325e-156	499.0	COG4521@1|root,COG4521@2|Bacteria,1MVH2@1224|Proteobacteria,2VINJ@28216|Betaproteobacteria,4ADDJ@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM taurine ABC transporter, periplasmic binding protein	tauA1	-	-	ko:K15551	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	NMT1,NMT1_2
PYH2_k127_1306092_2	543728.Vapar_3845	6.267e-142	454.0	COG4525@1|root,COG4525@2|Bacteria,1QTUA@1224|Proteobacteria,2VIKA@28216|Betaproteobacteria,4AA0C@80864|Comamonadaceae	28216|Betaproteobacteria	P	ABC transporter	tauB	-	3.6.3.36	ko:K10831	ko00920,ko02010,map00920,map02010	M00435	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.1,3.A.1.17.4	-	-	ABC_tran
PYH2_k127_1306092_1	543728.Vapar_3844	1.176e-142	455.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VJM9@28216|Betaproteobacteria,4ACII@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	tauC	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
PYH2_k127_1306092_3	684949.ATTJ01000001_gene2089	9.993e-102	339.0	COG0500@1|root,COG2226@2|Bacteria,1WMEJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1306092_4	667632.KB890198_gene1132	1.118e-78	268.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,2VW59@28216|Betaproteobacteria,1KHAS@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N
PYH2_k127_1306092_9	243231.GSU3487	2.445e-22	103.0	2E33J@1|root,32Y3P@2|Bacteria,1N9JJ@1224|Proteobacteria,430TT@68525|delta/epsilon subdivisions,2WVSC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1306092_7	261292.Nit79A3_2987	1.057e-45	168.0	COG4190@1|root,COG4190@2|Bacteria,1N3VQ@1224|Proteobacteria,2VUVX@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1306092_8	983917.RGE_21800	1.647e-34	139.0	2F27V@1|root,33V61@2|Bacteria,1NVDD@1224|Proteobacteria,2W1VV@28216|Betaproteobacteria,1KNJN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1306092_6	395495.Lcho_1814	1.789e-49	178.0	COG1126@1|root,COG1126@2|Bacteria,1MWKQ@1224|Proteobacteria,2VJYN@28216|Betaproteobacteria,1KKK9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
PYH2_k127_1314480_0	614083.AWQR01000055_gene1969	2.808e-134	440.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,4A9MA@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
PYH2_k127_1314480_2	864051.BurJ1DRAFT_2865	1.364e-78	269.0	COG1309@1|root,COG1309@2|Bacteria,1MVQV@1224|Proteobacteria,2VK6A@28216|Betaproteobacteria,1KKUU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_11,TetR_N
PYH2_k127_1314480_1	864051.BurJ1DRAFT_2866	1.118e-100	352.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,2VJVW@28216|Betaproteobacteria,1KJY9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	nolF	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PYH2_k127_1331889_7	1211115.ALIQ01000089_gene4457	1.184e-65	226.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	puuC	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_1331889_4	999547.KI421500_gene3097	4.898e-104	347.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,280JA@191028|Leisingera	28211|Alphaproteobacteria	IQ	KR domain	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_1331889_8	483219.LILAB_30740	1.049e-36	142.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,430Y1@68525|delta/epsilon subdivisions,2WVU4@28221|Deltaproteobacteria,2YVFD@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
PYH2_k127_1331889_2	267608.RSc0992	1.738e-116	387.0	COG0625@1|root,COG3832@1|root,COG0625@2|Bacteria,COG3832@2|Bacteria,1RC4Y@1224|Proteobacteria,2VW3S@28216|Betaproteobacteria,1KH88@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gstF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	AHSA1,GST_C,GST_N,GST_N_3
PYH2_k127_1331889_1	864051.BurJ1DRAFT_0236	3.333e-193	609.0	COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,2VHNH@28216|Betaproteobacteria,1KK6G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Aminotransferase class I and II	tyrB	-	2.6.1.57	ko:K00832	ko00270,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	M00024,M00025,M00034,M00040	R00694,R00734,R01731,R07396,R10845	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH2_k127_1331889_6	420662.Mpe_A3685	5.826e-74	253.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2VR4K@28216|Betaproteobacteria,1KKJB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
PYH2_k127_1331889_5	987059.RBXJA2T_18894	8.176e-91	325.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria,1KK13@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_1331889_0	420662.Mpe_A3563	5.82e-229	715.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,1KJ7R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator	lplT	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_1331889_3	983917.RGE_01690	2.966e-111	366.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,1KJUS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
PYH2_k127_1336329_0	864051.BurJ1DRAFT_4547	1.737e-309	954.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
PYH2_k127_1336329_1	395495.Lcho_2151	4.327e-130	418.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria,1KJCA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	porB	-	1.2.1.58,1.2.7.1	ko:K00170,ko:K18356	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_11,Fer4_6,TPP_enzyme_C
PYH2_k127_1342443_3	420662.Mpe_A0457	3.391e-66	232.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,1KJT6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PYH2_k127_1342443_0	395495.Lcho_0516	1.853e-259	816.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,1KJCM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
PYH2_k127_1342443_5	987059.RBXJA2T_14306	2.81e-20	98.0	COG3116@1|root,COG3116@2|Bacteria,1N95M@1224|Proteobacteria,2VVTP@28216|Betaproteobacteria,1KMIW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
PYH2_k127_1342443_1	983917.RGE_09460	2.979e-133	430.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,1KJKM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
PYH2_k127_1342443_4	1265502.KB905949_gene953	3.468e-53	192.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,4ADKY@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
PYH2_k127_1342443_2	1123400.KB904791_gene102	6.934e-73	250.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,1S3PX@1236|Gammaproteobacteria,460Q7@72273|Thiotrichales	72273|Thiotrichales	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
PYH2_k127_1342443_6	395495.Lcho_2134	3.527e-17	85.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,1KMKS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1352917_10	420662.Mpe_A2925	1.689e-64	222.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,1KKVP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Lactoylglutathione lyase	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
PYH2_k127_1352917_7	62928.azo2453	1.325e-69	241.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,2VRAJ@28216|Betaproteobacteria,2KWSA@206389|Rhodocyclales	206389|Rhodocyclales	K	Putative FMN-binding domain	-	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
PYH2_k127_1352917_11	395495.Lcho_1716	1.029e-26	119.0	COG3350@1|root,COG3350@2|Bacteria,1PX0Q@1224|Proteobacteria,2W0V4@28216|Betaproteobacteria,1KNB3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1352917_4	864051.BurJ1DRAFT_1587	2.631e-98	326.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,2VQWM@28216|Betaproteobacteria,1KJU8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
PYH2_k127_1352917_0	1236959.BAMT01000001_gene1013	7.353e-285	885.0	COG0129@1|root,COG0129@2|Bacteria,1MU3T@1224|Proteobacteria,2VHH2@28216|Betaproteobacteria,2KMF8@206350|Nitrosomonadales	206350|Nitrosomonadales	EG	Belongs to the IlvD Edd family	-	-	4.2.1.12	ko:K01690	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00008	R02036	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH2_k127_1352917_5	864051.BurJ1DRAFT_1585	4.515e-80	273.0	COG3703@1|root,COG3703@2|Bacteria,1QA7D@1224|Proteobacteria,2VQKU@28216|Betaproteobacteria,1KKY0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides	chaC	-	-	ko:K07232	-	-	-	-	ko00000	-	-	-	ChaC
PYH2_k127_1352917_9	395495.Lcho_2921	8.078e-65	228.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VRAE@28216|Betaproteobacteria,1KKXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	MobA-like NTP transferase domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
PYH2_k127_1352917_3	983917.RGE_34500	1.464e-105	346.0	COG0259@1|root,COG0259@2|Bacteria,1NZUU@1224|Proteobacteria,2VIXW@28216|Betaproteobacteria,1KKC8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Hemerythrin,PNP_phzG_C,Putative_PNPOx
PYH2_k127_1352917_6	595537.Varpa_4294	3.917e-75	256.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VR6F@28216|Betaproteobacteria,4ADFU@80864|Comamonadaceae	28216|Betaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
PYH2_k127_1352917_8	864051.BurJ1DRAFT_1576	1.233e-68	243.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSH4@28216|Betaproteobacteria,1KM65@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
PYH2_k127_1352917_1	420662.Mpe_A2936	5.488e-270	837.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,1KKD7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the UbiD family	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
PYH2_k127_1352917_2	864051.BurJ1DRAFT_1574	6.471e-108	357.0	COG0741@1|root,COG0741@2|Bacteria,1RAP3@1224|Proteobacteria,2VQXG@28216|Betaproteobacteria,1KJ11@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	lytic transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	SLT
PYH2_k127_1380075_1	215803.DB30_0841	2.422e-54	207.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,438M3@68525|delta/epsilon subdivisions,2X1ZS@28221|Deltaproteobacteria,2YX8A@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
PYH2_k127_1380075_0	1437824.BN940_10591	7.679e-198	625.0	COG1861@1|root,COG1861@2|Bacteria,1QU5J@1224|Proteobacteria,2W02U@28216|Betaproteobacteria,3T8BI@506|Alcaligenaceae	28216|Betaproteobacteria	M	Transposase DDE domain group 1	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
PYH2_k127_1380075_2	543728.Vapar_2258	2.073e-16	80.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,4AAP5@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
PYH2_k127_1401519_8	1380394.JADL01000001_gene2369	2.535e-09	59.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria,2JQ3W@204441|Rhodospirillales	204441|Rhodospirillales	K	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
PYH2_k127_1401519_2	246200.SPOA0386	6.661e-230	722.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2TQKQ@28211|Alphaproteobacteria,4NBWG@97050|Ruegeria	28211|Alphaproteobacteria	C	Belongs to the GMC oxidoreductase family	-	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
PYH2_k127_1401519_3	1380394.JADL01000001_gene2365	1.892e-198	631.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2TUMK@28211|Alphaproteobacteria,2JPB1@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
PYH2_k127_1401519_7	2903.EOD23273	1.552e-43	178.0	29PKT@1|root,2RWYF@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1401519_1	1276756.AUEX01000042_gene2648	1.353e-282	888.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,4AAS9@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	iorB1	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2
PYH2_k127_1401519_6	1502852.FG94_00058	8.589e-74	250.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ9M@28216|Betaproteobacteria,474CY@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	[2Fe-2S] binding domain	iorA	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_1401519_5	1333856.L686_04425	1.573e-79	271.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,1S4K8@1236|Gammaproteobacteria,1Z3JU@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	5.99.1.4	ko:K14584	ko00626,ko01100,ko01120,ko01220,map00626,map01100,map01120,map01220	M00534	R05137	RC03084	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	DSBA
PYH2_k127_1401519_4	398578.Daci_5357	2.462e-120	392.0	COG1028@1|root,COG1028@2|Bacteria,1MWJQ@1224|Proteobacteria,2VIQH@28216|Betaproteobacteria,4ACY5@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH2_k127_1401519_0	296591.Bpro_3532	0.0	1074.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,4AAUE@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.25,4.2.1.82,4.2.1.9	ko:K01687,ko:K13875,ko:K22186	ko00040,ko00053,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00053,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R02522,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH2_k127_1433478_42	887062.HGR_03387	2.026e-07	59.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,4ADP4@80864|Comamonadaceae	28216|Betaproteobacteria	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
PYH2_k127_1433478_22	1265502.KB905938_gene2446	1.953e-131	435.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,4AA0X@80864|Comamonadaceae	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
PYH2_k127_1433478_18	987059.RBXJA2T_15488	2.424e-144	460.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,1KK3M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
PYH2_k127_1433478_28	420662.Mpe_A0834	4.49e-111	362.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,1KJ6B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
PYH2_k127_1433478_31	1265502.KB905938_gene2443	8.797e-103	339.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,4AAWV@80864|Comamonadaceae	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
PYH2_k127_1433478_12	395495.Lcho_1588	3.064e-156	521.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,1KK22@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH2_k127_1433478_4	987059.RBXJA2T_15468	1.088e-223	700.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,1KJRP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
PYH2_k127_1433478_32	987059.RBXJA2T_15463	4.421e-102	335.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,1KJJA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
PYH2_k127_1433478_8	864051.BurJ1DRAFT_4470	1.21e-210	660.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,1KK68@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
PYH2_k127_1433478_38	1265502.KB905938_gene2438	3.239e-36	140.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,4AF8B@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
PYH2_k127_1433478_25	1265502.KB905938_gene2437	2.833e-126	408.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,4AAEE@80864|Comamonadaceae	28216|Betaproteobacteria	V	Transport permease protein	yadH	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
PYH2_k127_1433478_17	395495.Lcho_1582	2.764e-147	473.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,1KJUB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ABC transporter	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_1433478_29	420662.Mpe_A0825	1.832e-110	361.0	COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,2VIDN@28216|Betaproteobacteria,1KKHE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
PYH2_k127_1433478_23	864051.BurJ1DRAFT_4476	2.114e-130	419.0	COG0457@1|root,COG0457@2|Bacteria,1R3PT@1224|Proteobacteria,2VN88@28216|Betaproteobacteria,1KKRT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1433478_5	420662.Mpe_A3084	8.362e-220	699.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VIJ1@28216|Betaproteobacteria,1KKIM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
PYH2_k127_1433478_39	864051.BurJ1DRAFT_1189	1.099e-32	147.0	COG4281@1|root,COG4281@2|Bacteria,1MZPP@1224|Proteobacteria,2VUK0@28216|Betaproteobacteria,1KM9E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	acyl-coA-binding protein	acb	-	-	-	-	-	-	-	-	-	-	-	ACBP
PYH2_k127_1433478_37	864051.BurJ1DRAFT_1182	3.104e-40	163.0	2EGJT@1|root,33ABY@2|Bacteria,1NGI4@1224|Proteobacteria,2VX3Y@28216|Betaproteobacteria,1KMI2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn)	-	-	-	-	-	-	-	-	-	-	-	-	PHA_gran_rgn
PYH2_k127_1433478_13	864051.BurJ1DRAFT_1181	3.648e-151	499.0	COG4324@1|root,COG4324@2|Bacteria,1N0FE@1224|Proteobacteria,2VH73@28216|Betaproteobacteria,1KKFH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Aminopep
PYH2_k127_1433478_0	420662.Mpe_A3090	0.0	1088.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,2VHHZ@28216|Betaproteobacteria,1KJMR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
PYH2_k127_1433478_16	864051.BurJ1DRAFT_1179	4.178e-148	482.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria,1KMCB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH2_k127_1433478_30	543728.Vapar_3731	3.679e-105	348.0	COG3221@1|root,COG3221@2|Bacteria,1MYRC@1224|Proteobacteria,2VTJP@28216|Betaproteobacteria,4AEMW@80864|Comamonadaceae	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
PYH2_k127_1433478_6	864051.BurJ1DRAFT_1178	9.016e-219	686.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VIS0@28216|Betaproteobacteria,1KJJ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_1433478_11	1265502.KB905939_gene2394	3.798e-159	509.0	COG2866@1|root,COG2866@2|Bacteria,1N6CX@1224|Proteobacteria,2VHWB@28216|Betaproteobacteria,4AAF4@80864|Comamonadaceae	28216|Betaproteobacteria	E	Protein of unknown function (DUF2817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2817
PYH2_k127_1433478_20	338969.Rfer_2327	6.314e-134	429.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,4ABJC@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	aapP	-	3.6.3.21	ko:K02028,ko:K09972	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
PYH2_k127_1433478_19	338969.Rfer_2326	3.282e-143	464.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,2VIXA@28216|Betaproteobacteria,4ABBP@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	aapM	-	-	ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
PYH2_k127_1433478_27	1089552.KI911559_gene1942	5.542e-119	395.0	COG4597@1|root,COG4597@2|Bacteria,1MV0S@1224|Proteobacteria,2TR7G@28211|Alphaproteobacteria,2JQ13@204441|Rhodospirillales	204441|Rhodospirillales	E	acid transport system permease	-	-	-	ko:K09970	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
PYH2_k127_1433478_10	614083.AWQR01000005_gene1158	5.726e-162	521.0	COG0834@1|root,COG0834@2|Bacteria,1MV5D@1224|Proteobacteria,2VIN1@28216|Betaproteobacteria,4AAWT@80864|Comamonadaceae	28216|Betaproteobacteria	ET	extracellular solute-binding protein, family 3	aapJ	-	-	ko:K02030,ko:K09969,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.19,3.A.1.3.4,3.A.1.3.7,3.A.1.3.8	-	-	SBP_bac_3
PYH2_k127_1433478_36	864051.BurJ1DRAFT_1171	6.532e-54	197.0	COG1011@1|root,COG1011@2|Bacteria,1Q69Z@1224|Proteobacteria,2VQKJ@28216|Betaproteobacteria,1KM50@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
PYH2_k127_1433478_2	987059.RBXJA2T_15383	8.704e-267	829.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,2VHR9@28216|Betaproteobacteria,1KJDK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
PYH2_k127_1433478_15	1265502.KB905939_gene2392	2.001e-150	481.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,4AA60@80864|Comamonadaceae	28216|Betaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
PYH2_k127_1433478_14	543728.Vapar_1099	1.587e-150	484.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,4AD8V@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	fbpC	-	3.6.3.30	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	M00190,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.11	-	-	ABC_tran,TOBE_2
PYH2_k127_1433478_1	864051.BurJ1DRAFT_1167	0.0	1037.0	COG1178@1|root,COG1178@2|Bacteria,1MXZZ@1224|Proteobacteria,2VI17@28216|Betaproteobacteria,1KM8D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
PYH2_k127_1433478_9	864051.BurJ1DRAFT_1166	1.719e-190	599.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2VKTZ@28216|Betaproteobacteria,1KMG2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
PYH2_k127_1433478_3	1286631.X805_18840	1.115e-264	820.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria,1KJDH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
PYH2_k127_1433478_21	1265502.KB905939_gene2390	2.535e-132	429.0	COG1737@1|root,COG1737@2|Bacteria,1MV3U@1224|Proteobacteria,2VH1T@28216|Betaproteobacteria,4AB7K@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix protein RpiR	hexR	-	-	ko:K19337	-	-	-	-	ko00000,ko03000	-	-	-	HTH_6,SIS
PYH2_k127_1433478_41	864051.BurJ1DRAFT_1163	5.044e-11	71.0	COG3113@1|root,COG3113@2|Bacteria,1N9WV@1224|Proteobacteria,2VW67@28216|Betaproteobacteria,1KMSY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	STAS domain	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
PYH2_k127_1433478_33	395495.Lcho_3390	9.089e-84	284.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,1KKN9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	toluene tolerance	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
PYH2_k127_1433478_34	1286631.X805_18800	7.025e-74	265.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,1KM03@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	MlaA lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
PYH2_k127_1433478_35	864051.BurJ1DRAFT_1160	6.321e-63	220.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,1KKU2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	MlaD protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
PYH2_k127_1433478_26	987059.RBXJA2T_01025	1.448e-122	410.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,1KJC0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Permease MlaE	ttg2B	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
PYH2_k127_1433478_24	864051.BurJ1DRAFT_1158	7.712e-129	418.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,1KIX8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	ABC transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
PYH2_k127_1433478_40	1286631.X805_20140	1.899e-13	79.0	2AXWX@1|root,31PY5@2|Bacteria,1QMKZ@1224|Proteobacteria,2W9V8@28216|Betaproteobacteria,1KNWK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1433478_7	375286.mma_3355	2.196e-213	694.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,472QP@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
PYH2_k127_144864_3	1265502.KB905935_gene3099	8.983e-189	599.0	COG2270@1|root,COG2270@2|Bacteria,1MWXB@1224|Proteobacteria,2VKNE@28216|Betaproteobacteria,4AA7P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
PYH2_k127_144864_6	365044.Pnap_1223	2.751e-134	432.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VHXJ@28216|Betaproteobacteria,4ABCD@80864|Comamonadaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
PYH2_k127_144864_4	420662.Mpe_A1297	4.756e-157	499.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VI6W@28216|Betaproteobacteria,1KJ8F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
PYH2_k127_144864_1	1265502.KB905930_gene1417	1.256e-308	954.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VGZD@28216|Betaproteobacteria,4A9JW@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
PYH2_k127_144864_5	864051.BurJ1DRAFT_2979	9.37e-157	504.0	COG2070@1|root,COG2070@2|Bacteria,1MU0U@1224|Proteobacteria,2VH48@28216|Betaproteobacteria,1KJPP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
PYH2_k127_144864_7	1157708.KB907451_gene4803	1.369e-132	434.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,2VP3I@28216|Betaproteobacteria,4AE4X@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
PYH2_k127_144864_2	864051.BurJ1DRAFT_2978	3.995e-279	864.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VHCV@28216|Betaproteobacteria,1KJIQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH2_k127_144864_0	864051.BurJ1DRAFT_2972	0.0	1760.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,1KJXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
PYH2_k127_144864_8	864051.BurJ1DRAFT_2971	9.645e-58	203.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,1KIX4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH2_k127_1463267_2	1265502.KB905941_gene2902	2.048e-96	318.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,4AAUH@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
PYH2_k127_1463267_1	1265502.KB905941_gene2903	2.892e-232	739.0	COG0415@1|root,COG0415@2|Bacteria,1MV9Y@1224|Proteobacteria,2VITS@28216|Betaproteobacteria,4ACPK@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM DNA photolyase, FAD-binding	phrB	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
PYH2_k127_1463267_0	1265502.KB905941_gene2905	1.306e-295	919.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4ABCW@80864|Comamonadaceae	28216|Betaproteobacteria	T	ATP-binding region, ATPase domain protein	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
PYH2_k127_1495991_3	864051.BurJ1DRAFT_2102	1.3e-36	142.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,1KJ8Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
PYH2_k127_1495991_1	1286631.X805_32350	6.417e-182	572.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,1KIXQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
PYH2_k127_1495991_2	864051.BurJ1DRAFT_2100	7.222e-113	369.0	COG0122@1|root,COG0122@2|Bacteria,1MX9C@1224|Proteobacteria,2VHMQ@28216|Betaproteobacteria,1KJ78@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	endonuclease III	alkA	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
PYH2_k127_1495991_0	1265502.KB905930_gene1486	2.231e-228	717.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,4ABUH@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
PYH2_k127_1515700_0	420662.Mpe_A1120	0.0	1145.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,1KKCX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Ftsk_gamma	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
PYH2_k127_1515700_2	983917.RGE_34120	2.896e-81	276.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,1KKPS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
PYH2_k127_1515700_1	420662.Mpe_A1122	6.712e-83	278.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,1KJWQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
PYH2_k127_1542742_0	864051.BurJ1DRAFT_2487	0.0	1097.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VI3T@28216|Betaproteobacteria,1KKBU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Acetyl-coenzyme A synthetase N-terminus	prpE	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
PYH2_k127_1542742_4	864051.BurJ1DRAFT_2486	4.582e-57	204.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,1KKZC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Cell wall-associated	-	-	-	ko:K13695,ko:K19303	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
PYH2_k127_1542742_2	1265502.KB905935_gene3084	6.401e-172	547.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,4AB8M@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
PYH2_k127_1542742_3	864051.BurJ1DRAFT_1333	1.785e-84	287.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,1KKJ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
PYH2_k127_1542742_1	1095769.CAHF01000011_gene2032	1.654e-173	555.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VH78@28216|Betaproteobacteria,473QZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	moeA2	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
PYH2_k127_1542742_5	395495.Lcho_1719	1.869e-35	139.0	COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,2VU4A@28216|Betaproteobacteria,1KMQ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Small Multidrug Resistance protein	emrE	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
PYH2_k127_1554602_0	1265502.KB905933_gene2053	0.0	1023.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,4A9JK@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
PYH2_k127_1554602_1	864051.BurJ1DRAFT_4826	3.889e-128	416.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,1KJFI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
PYH2_k127_1554602_3	653733.Selin_0324	7.585e-65	226.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	ynjA	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	CMD
PYH2_k127_1554602_2	1538295.JY96_05075	2.208e-123	400.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,2VHR3@28216|Betaproteobacteria,1KJQK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
PYH2_k127_1584178_4	1265502.KB905929_gene2215	9.031e-75	259.0	COG1028@1|root,COG1028@2|Bacteria,1RH9P@1224|Proteobacteria,2VNFB@28216|Betaproteobacteria,4ABK2@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH2_k127_1584178_5	931627.MycrhDRAFT_3071	6.972e-34	145.0	COG3806@1|root,COG4413@1|root,COG3806@2|Bacteria,COG4413@2|Bacteria,2I0UR@201174|Actinobacteria,23EP2@1762|Mycobacteriaceae	201174|Actinobacteria	E	Urea transporter	-	-	-	-	-	-	-	-	-	-	-	-	UT
PYH2_k127_1584178_2	1440774.Y900_021380	2.503e-217	682.0	COG0154@1|root,COG0549@1|root,COG0154@2|Bacteria,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,23641@1762|Mycobacteriaceae	201174|Actinobacteria	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PYH2_k127_1584178_0	931627.MycrhDRAFT_4456	1.89e-257	810.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria,234MN@1762|Mycobacteriaceae	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
PYH2_k127_1584178_1	931627.MycrhDRAFT_4457	1.767e-221	703.0	COG0074@1|root,COG0074@2|Bacteria,2GN20@201174|Actinobacteria,23D72@1762|Mycobacteriaceae	201174|Actinobacteria	C	CoA binding domain	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
PYH2_k127_1584178_6	1158608.I583_03237	2.122e-10	72.0	2DBAX@1|root,2Z84Q@2|Bacteria,1VHQG@1239|Firmicutes,4HPN3@91061|Bacilli,4B1NJ@81852|Enterococcaceae	91061|Bacilli	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
PYH2_k127_1584178_3	931627.MycrhDRAFT_4458	4.826e-116	376.0	COG1335@1|root,COG1335@2|Bacteria,2I9AW@201174|Actinobacteria,235EF@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Hydrolase	-	-	3.5.1.110	ko:K09020	ko00240,ko01100,map00240,map01100	-	R09947,R09980	RC02737,RC02738	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
PYH2_k127_1591084_3	1232410.KI421412_gene342	3.701e-82	278.0	2DKA3@1|root,30905@2|Bacteria,1RGG6@1224|Proteobacteria	1224|Proteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
PYH2_k127_1591084_15	614083.AWQR01000025_gene3719	1.252e-28	118.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria,4AFCE@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1591084_13	748247.AZKH_2009	3.699e-39	148.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,2VWDQ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1591084_16	864051.BurJ1DRAFT_1874	1.394e-28	126.0	2CBKU@1|root,32WBU@2|Bacteria,1N2RW@1224|Proteobacteria,2VV0A@28216|Betaproteobacteria,1KMUZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	manually curated	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1591084_9	1278309.KB907099_gene2766	3.439e-63	224.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria,1SRHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1591084_20	1235457.C404_08080	7.493e-15	85.0	2EKQ7@1|root,33EDZ@2|Bacteria,1NHK0@1224|Proteobacteria,2W4W2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2845
PYH2_k127_1591084_14	269799.Gmet_3000	5.571e-34	140.0	2E3Q3@1|root,32YN2@2|Bacteria,1NB4I@1224|Proteobacteria,431RU@68525|delta/epsilon subdivisions,2WWKH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1591084_12	1095769.CAHF01000015_gene2791	9.404e-47	180.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,2VVH4@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH2_k127_1591084_1	864051.BurJ1DRAFT_3792	1.477e-102	344.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,2VI8F@28216|Betaproteobacteria,1KMW9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
PYH2_k127_1591084_2	420662.Mpe_A2184	4.564e-94	320.0	29SCQ@1|root,32R95@2|Bacteria,1RIT7@1224|Proteobacteria,2VSUG@28216|Betaproteobacteria,1KM4E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1591084_0	420662.Mpe_A1369	3.337e-126	412.0	COG2354@1|root,COG2354@2|Bacteria,1MVYU@1224|Proteobacteria,2VHTU@28216|Betaproteobacteria,1KJK3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF808)	yedI	-	-	ko:K09781	-	-	-	-	ko00000	-	-	-	DUF808
PYH2_k127_1591084_11	1121920.AUAU01000011_gene222	7.237e-55	197.0	COG3189@1|root,COG3189@2|Bacteria,3Y86R@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
PYH2_k127_1591084_19	420662.Mpe_A2174	4.816e-18	87.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,1KMKS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1591084_17	535289.Dtpsy_3453	5.968e-21	95.0	COG1256@1|root,COG1256@2|Bacteria,1NMP9@1224|Proteobacteria,2VVX1@28216|Betaproteobacteria,4AFNB@80864|Comamonadaceae	28216|Betaproteobacteria	N	Flagellar basal body rod protein	-	-	-	-	-	-	-	-	-	-	-	-	Flg_bb_rod,Flg_bbr_C
PYH2_k127_1591084_4	365046.Rta_27090	3.315e-76	261.0	COG0500@1|root,COG0500@2|Bacteria,1RDHE@1224|Proteobacteria,2VQIP@28216|Betaproteobacteria,4ADJ0@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Protein of unknown function (DUF938)	-	-	-	-	-	-	-	-	-	-	-	-	DUF938
PYH2_k127_1591084_8	1121022.ABENE_02635	1.084e-63	223.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2U70T@28211|Alphaproteobacteria,2KGND@204458|Caulobacterales	204458|Caulobacterales	O	SelR domain	-	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
PYH2_k127_1591084_5	404380.Gbem_0264	3.02e-74	258.0	COG0225@1|root,COG0225@2|Bacteria,1R33Z@1224|Proteobacteria,42RS2@68525|delta/epsilon subdivisions,2X9GK@28221|Deltaproteobacteria,43W2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
PYH2_k127_1591084_7	1038859.AXAU01000002_gene767	1.937e-71	256.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_3,Cupredoxin_1
PYH2_k127_1591084_10	1095769.CAHF01000005_gene1534	2.382e-57	209.0	COG2135@1|root,COG2135@2|Bacteria,1RFZU@1224|Proteobacteria,2VQDU@28216|Betaproteobacteria,477BF@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
PYH2_k127_1591084_6	338969.Rfer_1149	8.18e-72	249.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria,4AB02@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
PYH2_k127_1617689_3	1040982.AXAL01000010_gene4149	6.279e-87	290.0	COG0111@1|root,COG0111@2|Bacteria,1NU4B@1224|Proteobacteria,2TRM8@28211|Alphaproteobacteria,43NZ1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase catalytic	MA20_13185	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH2_k127_1617689_8	1538295.JY96_14600	1.542e-48	177.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,2VUHB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1617689_6	55207.KP22_10375	2.078e-55	214.0	COG3170@1|root,COG3170@2|Bacteria,1QV88@1224|Proteobacteria,1T29N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
PYH2_k127_1617689_1	240016.ABIZ01000001_gene2819	1.844e-222	704.0	COG5421@1|root,COG5421@2|Bacteria,46U8B@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PYH2_k127_1617689_4	983917.RGE_46910	1.2e-85	295.0	COG1639@1|root,COG1639@2|Bacteria,1PQZH@1224|Proteobacteria,2VQK4@28216|Betaproteobacteria,1KKZB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	signal transduction protein	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
PYH2_k127_1617689_0	420662.Mpe_A3803	7.35e-277	858.0	COG2303@1|root,COG2303@2|Bacteria,1MV19@1224|Proteobacteria,2VI6F@28216|Betaproteobacteria,1KJR1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the GMC oxidoreductase family	betA	-	1.1.99.1	ko:K00108	ko00260,ko01100,map00260,map01100	M00555	R01025	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
PYH2_k127_1617689_2	983917.RGE_46930	2.261e-108	355.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2VIBH@28216|Betaproteobacteria,1KKGC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	UPF0056 inner membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
PYH2_k127_1617689_5	1265502.KB905947_gene1072	5.378e-81	279.0	COG0614@1|root,COG0614@2|Bacteria,1N53X@1224|Proteobacteria,2VN8J@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Pfam Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
PYH2_k127_1617689_7	864051.BurJ1DRAFT_5009	3.747e-49	177.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
PYH2_k127_1618062_2	864051.BurJ1DRAFT_3902	5.941e-17	86.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,1KM4J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Transporter	dctP	-	-	ko:K11688,ko:K21395	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
PYH2_k127_1618062_0	670292.JH26_27210	2.021e-128	418.0	COG1638@1|root,COG1638@2|Bacteria,1MWAM@1224|Proteobacteria,2TTQ8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	TRAP-type C4-dicarboxylate transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH2_k127_1618062_1	864051.BurJ1DRAFT_3901	2.17e-37	142.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,2W9GM@28216|Betaproteobacteria,1KMM4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_1626291_3	543728.Vapar_4942	5.165e-61	218.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2VJSB@28216|Betaproteobacteria,4AGR7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
PYH2_k127_1626291_0	864051.BurJ1DRAFT_0251	0.0	1381.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,1KJ17@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	SWIB,Topoisom_bac,Toprim,Toprim_Crpt
PYH2_k127_1626291_2	864051.BurJ1DRAFT_0250	1.107e-76	264.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria,2VR5U@28216|Betaproteobacteria,1KKW9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cysteine-rich motif following a subset of SET domains	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
PYH2_k127_1626291_1	983917.RGE_44740	6.418e-84	295.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,1KKV9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	biotin lipoate A B protein ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
PYH2_k127_1626291_4	395495.Lcho_0226	5.596e-38	151.0	2DD05@1|root,2ZG0C@2|Bacteria,1RC2B@1224|Proteobacteria,2VQ0R@28216|Betaproteobacteria,1KM8Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1652483_0	1095769.CAHF01000023_gene591	1.569e-302	948.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,473CA@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	MMPL family	bepE	-	-	ko:K03296,ko:K18138,ko:K18902	ko01501,ko01503,map01501,map01503	M00647,M00698,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
PYH2_k127_1652483_1	1095769.CAHF01000023_gene592	1.186e-96	340.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria	28216|Betaproteobacteria	M	RND efflux system, outer membrane lipoprotein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
PYH2_k127_1652483_2	266264.Rmet_5219	3.811e-61	220.0	COG2930@1|root,COG2930@2|Bacteria,1RCYH@1224|Proteobacteria	1224|Proteobacteria	S	Las17-binding protein actin regulator	CT2216	-	-	-	-	-	-	-	-	-	-	-	Ysc84
PYH2_k127_1656878_1	987059.RBXJA2T_16507	3.464e-254	794.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,1KK6W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
PYH2_k127_1656878_0	864051.BurJ1DRAFT_1778	0.0	1012.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,1KIV0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
PYH2_k127_1656878_3	864051.BurJ1DRAFT_1777	4.413e-52	185.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,1KM2X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PYH2_k127_1656878_4	1276756.AUEX01000020_gene3410	1.009e-25	109.0	COG5416@1|root,COG5416@2|Bacteria,1N4UI@1224|Proteobacteria,2VU63@28216|Betaproteobacteria,4AEWA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
PYH2_k127_1656878_2	864051.BurJ1DRAFT_1775	2.699e-102	336.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,1KJJF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_7
PYH2_k127_1673094_2	864051.BurJ1DRAFT_2417	4.807e-25	113.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VPME@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_1673094_1	864051.BurJ1DRAFT_2414	5.315e-166	529.0	COG3181@1|root,COG3181@2|Bacteria,1P88K@1224|Proteobacteria,2VJJP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_1673094_0	381666.H16_B2544	5.627e-307	955.0	COG1752@1|root,COG4775@1|root,COG1752@2|Bacteria,COG4775@2|Bacteria,1MUM9@1224|Proteobacteria,2VJRI@28216|Betaproteobacteria,1KBZ2@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Surface antigen	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Bac_surface_Ag,POTRA,Patatin
PYH2_k127_169100_2	395495.Lcho_1219	1.245e-17	85.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,1KKBY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
PYH2_k127_169100_0	983917.RGE_15170	2.559e-148	476.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,1KJ4K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
PYH2_k127_169100_1	420662.Mpe_A2842	6.109e-67	233.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,1KJVT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
PYH2_k127_1698420_1	1123368.AUIS01000028_gene1326	6.904e-125	411.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,1RN49@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	COG0577 ABC-type antimicrobial peptide transport system permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_1698420_2	1123368.AUIS01000028_gene1327	1.436e-108	357.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RR3R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	(ABC) transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_1698420_0	522306.CAP2UW1_1185	2.17e-148	479.0	COG2358@1|root,COG2358@2|Bacteria,1MWSG@1224|Proteobacteria,2VJGN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
PYH2_k127_1708395_1	1538295.JY96_03900	2.178e-57	203.0	COG0745@1|root,COG0745@2|Bacteria,1RJB3@1224|Proteobacteria,2VRB3@28216|Betaproteobacteria,1KKXC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
PYH2_k127_1708395_0	1265502.KB905929_gene2187	9.904e-230	735.0	COG3920@1|root,COG3920@2|Bacteria,1NU8D@1224|Proteobacteria,2VNX9@28216|Betaproteobacteria,4AF61@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_2,PAS_4,PAS_8,PAS_9
PYH2_k127_1712909_1	864051.BurJ1DRAFT_4621	1.037e-122	404.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,1KJV8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
PYH2_k127_1712909_0	864051.BurJ1DRAFT_4622	0.0	1255.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,1KJYU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
PYH2_k127_1728030_0	748280.NH8B_0020	1.612e-182	576.0	COG0281@1|root,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VJ0U@28216|Betaproteobacteria,2KPUG@206351|Neisseriales	206351|Neisseriales	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
PYH2_k127_1728030_1	1349767.GJA_358	6.308e-114	370.0	COG0625@1|root,COG0625@2|Bacteria,1MXHH@1224|Proteobacteria,2VH95@28216|Betaproteobacteria,472S2@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	gstA	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_3
PYH2_k127_1728030_2	296591.Bpro_4246	2.895e-54	192.0	COG0406@1|root,COG0406@2|Bacteria,1RB0S@1224|Proteobacteria,2VJR8@28216|Betaproteobacteria,4AABW@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PYH2_k127_1737840_1	1504672.669784575	1.639e-169	539.0	COG1063@1|root,COG1063@2|Bacteria,1MWX0@1224|Proteobacteria,2VKWS@28216|Betaproteobacteria,4AJ6V@80864|Comamonadaceae	28216|Betaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_1737840_2	864051.BurJ1DRAFT_4015	1.297e-118	385.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,1KJSX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	ThiF family	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
PYH2_k127_1737840_0	864051.BurJ1DRAFT_1397	2.494e-247	775.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,1KJHF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
PYH2_k127_1737840_3	420662.Mpe_A1085	3.961e-115	373.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,1KJ77@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
PYH2_k127_1745662_0	864051.BurJ1DRAFT_3614	0.0	1226.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,1KJ8C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
PYH2_k127_1745662_13	1265502.KB905936_gene2669	7.706e-42	157.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,4AEI9@80864|Comamonadaceae	28216|Betaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
PYH2_k127_1745662_5	987059.RBXJA2T_12647	1.246e-171	546.0	COG0436@1|root,COG0436@2|Bacteria,1MX6F@1224|Proteobacteria,2VJI9@28216|Betaproteobacteria,1KK60@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
PYH2_k127_1745662_6	420662.Mpe_A1395	3.758e-161	514.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,1KK5I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
PYH2_k127_1745662_14	420662.Mpe_A1394	5.084e-19	91.0	2EVBW@1|root,33NSD@2|Bacteria,1NPWD@1224|Proteobacteria,2VYYP@28216|Betaproteobacteria,1KP2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1745662_12	420662.Mpe_A2257	1.278e-52	190.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,1KM0Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Ferredoxin, 2Fe-2S type, ISC system	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
PYH2_k127_1745662_2	1286631.X805_39100	4.205e-280	872.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,1KJ1Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
PYH2_k127_1745662_9	420662.Mpe_A2259	2.543e-65	228.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,1KKTV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
PYH2_k127_1745662_10	395495.Lcho_1045	2.429e-60	216.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,1KM71@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the HesB IscA family	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
PYH2_k127_1745662_8	365046.Rta_18370	1.613e-70	240.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,4ADIW@80864|Comamonadaceae	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
PYH2_k127_1745662_3	1265502.KB905931_gene1712	2.005e-237	737.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,4AABE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
PYH2_k127_1745662_7	420662.Mpe_A2263	1.632e-98	323.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,1KK06@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
PYH2_k127_1745662_11	420662.Mpe_A2264	1.343e-55	208.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,1KM3K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
PYH2_k127_1745662_1	420662.Mpe_A2287	0.0	1139.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,1KJZ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
PYH2_k127_1745662_4	1265502.KB905931_gene1707	1.352e-227	710.0	COG4553@1|root,COG4553@2|Bacteria,1MVUH@1224|Proteobacteria,2VIP8@28216|Betaproteobacteria,4A9MW@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM PHB de-polymerase domain protein	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	PHB_depo_C
PYH2_k127_1763427_1	420662.Mpe_A3733	5.768e-204	641.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,1KJWX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
PYH2_k127_1763427_0	864051.BurJ1DRAFT_3860	6.624e-210	665.0	COG3511@1|root,COG3511@2|Bacteria,1MVNS@1224|Proteobacteria,2VMDC@28216|Betaproteobacteria,1KK7X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
PYH2_k127_1763427_2	1265502.KB905944_gene692	6.233e-93	308.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,4ACTD@80864|Comamonadaceae	28216|Betaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
PYH2_k127_1782519_0	864051.BurJ1DRAFT_3970	3.641e-261	816.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,1KKC9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PYH2_k127_1782519_1	864051.BurJ1DRAFT_3969	3.739e-103	340.0	COG4671@1|root,COG4671@2|Bacteria,1NE6T@1224|Proteobacteria,2W2IM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C
PYH2_k127_1795224_0	338966.Ppro_0419	5.625e-286	893.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,42P3J@68525|delta/epsilon subdivisions,2WKFS@28221|Deltaproteobacteria,43U1C@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
PYH2_k127_1795224_1	414684.RC1_3562	3.38e-33	132.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria,2JR8S@204441|Rhodospirillales	204441|Rhodospirillales	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
PYH2_k127_1799751_3	543728.Vapar_3305	7.993e-55	195.0	COG2070@1|root,COG2070@2|Bacteria,1MU2F@1224|Proteobacteria,2VJ5B@28216|Betaproteobacteria,4AC0Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
PYH2_k127_1799751_0	748247.AZKH_0500	0.0	2083.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,2VKIR@28216|Betaproteobacteria,2KVIK@206389|Rhodocyclales	206389|Rhodocyclales	E	Bacterial NAD-glutamate dehydrogenase	gdh	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
PYH2_k127_1799751_4	296591.Bpro_1203	0.0003362	49.0	2C95V@1|root,34B1R@2|Bacteria,1P1M0@1224|Proteobacteria,2W4P3@28216|Betaproteobacteria,4AIHU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
PYH2_k127_1799751_2	1502851.FG93_00913	4.086e-137	451.0	2DBSD@1|root,2ZARI@2|Bacteria,1MX0F@1224|Proteobacteria,2TUNC@28211|Alphaproteobacteria,3JQX7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)	MA20_42050	-	-	-	-	-	-	-	-	-	-	-	GRDB
PYH2_k127_1799751_1	1095769.CAHF01000007_gene1650	9.154e-144	468.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,2VH7E@28216|Betaproteobacteria,473GY@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
PYH2_k127_180588_0	358220.C380_23050	0.0	1535.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,4AC8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
PYH2_k127_180588_1	420662.Mpe_A3505	2.89e-129	425.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,2VKGK@28216|Betaproteobacteria,1KN2B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Phospholipase A1	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
PYH2_k127_180588_2	395495.Lcho_0459	9.228e-76	259.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VS28@28216|Betaproteobacteria,1KKPZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome B561	cybB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
PYH2_k127_180588_3	1286631.X805_02110	1.431e-62	230.0	COG2353@1|root,COG2353@2|Bacteria,1RJFZ@1224|Proteobacteria,2VQHC@28216|Betaproteobacteria,1KKZG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
PYH2_k127_180588_4	1458275.AZ34_16245	7.408e-41	156.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria,4AC2Q@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
PYH2_k127_1852169_1	983917.RGE_24190	5.383e-53	196.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria,1KKWV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
PYH2_k127_1852169_0	983917.RGE_24200	3.58e-142	463.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VHRB@28216|Betaproteobacteria,1KKM1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_1852169_2	987059.RBXJA2T_08965	3.893e-44	163.0	COG0845@1|root,COG0845@2|Bacteria,1R3U4@1224|Proteobacteria,2VNQ2@28216|Betaproteobacteria,1KNFJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
PYH2_k127_1865713_6	1187851.A33M_4209	1.218e-94	334.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,PFOR_II,POR,POR_N,TPP_enzyme_C
PYH2_k127_1865713_5	1049564.TevJSym_bb00040	3.374e-103	351.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,1RZ7Y@1236|Gammaproteobacteria,1J5GQ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH2_k127_1865713_1	1049564.TevJSym_bb00050	6.625e-220	701.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,1S0WV@1236|Gammaproteobacteria,1J5KF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
PYH2_k127_1865713_0	1187851.A33M_4208	1.508e-232	731.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria,3FCY5@34008|Rhodovulum	28211|Alphaproteobacteria	E	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
PYH2_k127_1865713_3	1187851.A33M_4207	4.367e-147	472.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	gltA	-	1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14	ko:K00266,ko:K00528,ko:K02823	ko00240,ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248,R10159	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,Fer4_20,NAD_binding_1,Pyr_redox_2
PYH2_k127_1865713_4	1268237.G114_12538	2.296e-123	405.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,1RP78@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Belongs to the carbamate kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PYH2_k127_1865713_7	931627.MycrhDRAFT_4455	8.984e-17	88.0	COG0154@1|root,COG0549@1|root,COG0154@2|Bacteria,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,23641@1762|Mycobacteriaceae	201174|Actinobacteria	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PYH2_k127_1865713_2	1408418.JNJH01000004_gene1993	3.199e-173	556.0	COG2252@1|root,COG2252@2|Bacteria,1QVW3@1224|Proteobacteria,2TWKP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PERMEase	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
PYH2_k127_1871628_2	420662.Mpe_A2955	6.196e-43	166.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria,1KM2W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
PYH2_k127_1871628_0	1265502.KB905943_gene2720	6.26e-104	346.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,4AAWM@80864|Comamonadaceae	28216|Betaproteobacteria	U	Mota tolq exbb proton channel	tolQ	-	-	ko:K03561,ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	MotA_ExbB
PYH2_k127_1871628_1	864051.BurJ1DRAFT_1559	1.273e-45	169.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,1KM61@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	system-associated acyl-CoA thioesterase	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
PYH2_k127_1871628_3	1265502.KB905943_gene2722	1.209e-40	158.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria,4AFTV@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1871628_4	1265502.KB905943_gene2723	4.544e-21	95.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,4AD1S@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
PYH2_k127_1887063_2	420662.Mpe_A0337	8.545e-62	215.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,1KJAE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdhA1	-	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
PYH2_k127_1887063_1	1095769.CAHF01000007_gene1669	3.027e-117	381.0	COG0684@1|root,COG0684@2|Bacteria,1MUWV@1224|Proteobacteria,2VIJI@28216|Betaproteobacteria	28216|Betaproteobacteria	H	demethylmenaquinone methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
PYH2_k127_1887063_3	1458427.BAWN01000007_gene500	8.473e-58	205.0	COG3193@1|root,COG3193@2|Bacteria,1REF5@1224|Proteobacteria,2VT55@28216|Betaproteobacteria,4AEYR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
PYH2_k127_1887063_4	111781.Lepto7376_2074	3.486e-33	142.0	COG0346@1|root,COG0346@2|Bacteria,1GESA@1117|Cyanobacteria	1117|Cyanobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH2_k127_1887063_0	543728.Vapar_1696	6.705e-121	392.0	COG1073@1|root,COG1073@2|Bacteria,1QVD4@1224|Proteobacteria,2WHW5@28216|Betaproteobacteria,4AK30@80864|Comamonadaceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
PYH2_k127_1900347_1	420662.Mpe_A3516	3.355e-147	474.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2VKX4@28216|Betaproteobacteria,1KJ03@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD2	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
PYH2_k127_1900347_5	614083.AWQR01000056_gene3581	1.983e-66	231.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2VSZ8@28216|Betaproteobacteria,4ADFB@80864|Comamonadaceae	28216|Betaproteobacteria	M	Beta-Ig-H3 fasciclin	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
PYH2_k127_1900347_3	987059.RBXJA2T_04538	2.736e-94	320.0	COG2335@1|root,COG2335@2|Bacteria,1RD06@1224|Proteobacteria,2VT4Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Fasciclin domain	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin
PYH2_k127_1900347_4	420662.Mpe_A3699	1.612e-85	287.0	COG1309@1|root,COG1309@2|Bacteria,1P4J2@1224|Proteobacteria,2VHWF@28216|Betaproteobacteria,1KKRS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PYH2_k127_1900347_6	864051.BurJ1DRAFT_0550	1.601e-54	203.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria,1KM2Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_1900347_2	987059.RBXJA2T_05273	1.568e-94	319.0	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2VIHN@28216|Betaproteobacteria,1KJHN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
PYH2_k127_1900347_7	1286631.X805_26520	1.324e-34	140.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1QF7R@1224|Proteobacteria,2VP9G@28216|Betaproteobacteria,1KJUA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0149)	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
PYH2_k127_1900347_0	420662.Mpe_A3705	0.0	1049.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2VINZ@28216|Betaproteobacteria,1KJD0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
PYH2_k127_1905439_4	864051.BurJ1DRAFT_4516	8.789e-117	382.0	COG2425@1|root,COG2425@2|Bacteria,1N1RQ@1224|Proteobacteria,2VK1M@28216|Betaproteobacteria,1KJWG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2,VWA_CoxE
PYH2_k127_1905439_2	987059.RBXJA2T_01165	7.663e-161	520.0	COG2972@1|root,COG2972@2|Bacteria,1R5R0@1224|Proteobacteria,2VM7Q@28216|Betaproteobacteria,1KN1G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
PYH2_k127_1905439_3	983917.RGE_02710	1.712e-125	407.0	COG3279@1|root,COG3279@2|Bacteria,1R9Q4@1224|Proteobacteria,2WEES@28216|Betaproteobacteria,1KN7W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PYH2_k127_1905439_8	1265502.KB905958_gene237	2.113e-57	209.0	COG3714@1|root,COG3714@2|Bacteria,1N6QN@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
PYH2_k127_1905439_9	987059.RBXJA2T_01180	3.169e-12	68.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,1KJRB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PYH2_k127_1905439_5	1286631.X805_28170	1.527e-111	369.0	COG0679@1|root,COG0679@2|Bacteria,1PINE@1224|Proteobacteria,2VIH3@28216|Betaproteobacteria,1KKEN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PYH2_k127_1905439_0	983917.RGE_02130	1.892e-289	903.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,1KJN8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
PYH2_k127_1905439_1	420662.Mpe_A0134	1.009e-171	548.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,1KJ6M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
PYH2_k127_1905439_6	864051.BurJ1DRAFT_0192	1.677e-99	327.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria,1KK0R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
PYH2_k127_1905439_7	420662.Mpe_A0146	2.94e-84	285.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria,1KJZV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
PYH2_k127_1913633_0	1100720.ALKN01000037_gene1859	0.0	1283.0	COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,4ACF4@80864|Comamonadaceae	28216|Betaproteobacteria	CH	PFAM NADH flavin oxidoreductase NADH oxidase	abmA	-	1.14.13.40,1.3.1.34	ko:K00219,ko:K09461	ko00627,ko01120,map00627,map01120	-	R03998,R03999	RC00244	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,Oxidored_FMN
PYH2_k127_1913633_15	1157708.KB907453_gene4126	9.191e-69	240.0	COG1846@1|root,COG1846@2|Bacteria,1MZE9@1224|Proteobacteria,2VT2T@28216|Betaproteobacteria,4AE9M@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
PYH2_k127_1913633_4	365046.Rta_18150	7.062e-153	490.0	COG1024@1|root,COG1024@2|Bacteria,1MXHV@1224|Proteobacteria,2VHSP@28216|Betaproteobacteria,4AC2J@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	abmC	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_1913633_2	1123504.JQKD01000013_gene1062	4.782e-198	623.0	COG1960@1|root,COG1960@2|Bacteria,1MVQH@1224|Proteobacteria,2VIAN@28216|Betaproteobacteria,4AC8Z@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	abmD	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_1913633_17	543728.Vapar_1512	6.277e-47	178.0	COG0824@1|root,COG0824@2|Bacteria,1MZPN@1224|Proteobacteria,2VTCV@28216|Betaproteobacteria,4AF29@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM thioesterase superfamily protein	-	-	3.1.2.23	ko:K01075	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	4HBT,4HBT_2
PYH2_k127_1913633_16	397945.Aave_3169	3.427e-57	203.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2VSJ7@28216|Betaproteobacteria,4AE78@80864|Comamonadaceae	28216|Betaproteobacteria	J	endoribonuclease L-PSP	abmE	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH2_k127_1913633_21	987059.RBXJA2T_13474	4.414e-32	131.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,1KMGT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Belongs to the N-Me-Phe pilin family	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
PYH2_k127_1913633_10	1123399.AQVE01000002_gene2461	6.094e-99	331.0	COG0583@1|root,COG0583@2|Bacteria,1MXDQ@1224|Proteobacteria,1RPBS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_1913633_8	1185876.BN8_00658	5.615e-134	430.0	COG0693@1|root,COG0693@2|Bacteria,4NGII@976|Bacteroidetes,47K2N@768503|Cytophagia	976|Bacteroidetes	C	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
PYH2_k127_1913633_20	1244869.H261_00360	1.003e-34	139.0	COG3224@1|root,COG3224@2|Bacteria,1PYJ7@1224|Proteobacteria,2V0D7@28211|Alphaproteobacteria,2JYG6@204441|Rhodospirillales	204441|Rhodospirillales	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1913633_6	983917.RGE_41760	3.473e-146	469.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,1KJP4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	RNA polymerase sigma factor RpoH	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
PYH2_k127_1913633_14	983917.RGE_41770	1.899e-75	259.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,1KKS4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Electron transport protein SCO1 SenC	senC	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
PYH2_k127_1913633_7	1265502.KB905941_gene2876	2.529e-144	465.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VHZU@28216|Betaproteobacteria,4AAA5@80864|Comamonadaceae	28216|Betaproteobacteria	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
PYH2_k127_1913633_9	1265502.KB905941_gene2877	1.685e-127	419.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2VJ3C@28216|Betaproteobacteria,4AB9J@80864|Comamonadaceae	28216|Betaproteobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
PYH2_k127_1913633_13	1265502.KB905941_gene2878	1.008e-79	272.0	COG1999@1|root,COG1999@2|Bacteria,1RHK3@1224|Proteobacteria,2VRBY@28216|Betaproteobacteria,4A9Y4@80864|Comamonadaceae	28216|Betaproteobacteria	S	signal sequence binding	sco1	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1913633_19	626418.bglu_1g31620	3.476e-38	154.0	COG3346@1|root,COG3346@2|Bacteria,1MZUH@1224|Proteobacteria,2VSAZ@28216|Betaproteobacteria,1K3QH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SURF1-like protein	surf1	-	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
PYH2_k127_1913633_23	1286631.X805_19220	1.306e-20	93.0	2E53D@1|root,30XQ8@2|Bacteria,1PJJN@1224|Proteobacteria,2W9NN@28216|Betaproteobacteria,1KMVJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2909)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2909
PYH2_k127_1913633_5	864051.BurJ1DRAFT_4208	5.308e-149	482.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,2VJAP@28216|Betaproteobacteria,1KJDY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c oxidase subunit	coxC	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
PYH2_k127_1913633_22	1538295.JY96_05390	3.664e-22	100.0	2CDU3@1|root,33AS4@2|Bacteria,1NGWQ@1224|Proteobacteria,2VXNC@28216|Betaproteobacteria,1KMJR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2970)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2970
PYH2_k127_1913633_11	1286631.X805_19260	1.983e-91	306.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,2VHRQ@28216|Betaproteobacteria,1KJSY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	cytochrome C oxidase	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
PYH2_k127_1913633_1	420662.Mpe_A3180	0.0	1014.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,2VHGU@28216|Betaproteobacteria,1KKFU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
PYH2_k127_1913633_3	864051.BurJ1DRAFT_4213	5.233e-195	616.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,2VH9M@28216|Betaproteobacteria,1KJTP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3,OmpA
PYH2_k127_1913633_18	365046.Rta_33770	5.723e-42	161.0	COG5488@1|root,COG5488@2|Bacteria,1N5Z9@1224|Proteobacteria,2VU1W@28216|Betaproteobacteria,4AE03@80864|Comamonadaceae	28216|Betaproteobacteria	S	Integral membrane protein (DUF2244)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2244
PYH2_k127_1913633_12	864051.BurJ1DRAFT_4215	4.481e-86	293.0	COG4106@1|root,COG4106@2|Bacteria,1NG56@1224|Proteobacteria,2WGJ8@28216|Betaproteobacteria,1KKK2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
PYH2_k127_194534_9	420662.Mpe_A3410	6.494e-74	254.0	COG0500@1|root,COG0500@2|Bacteria,1QVHC@1224|Proteobacteria,2VS83@28216|Betaproteobacteria,1KKW7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	TPMT
PYH2_k127_194534_7	338969.Rfer_4086	8.098e-90	305.0	COG1639@1|root,COG1639@2|Bacteria,1R4ZN@1224|Proteobacteria,2VQ1P@28216|Betaproteobacteria,4ADH3@80864|Comamonadaceae	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
PYH2_k127_194534_5	1440774.Y900_017270	1.942e-113	377.0	COG0604@1|root,COG0604@2|Bacteria,2I66C@201174|Actinobacteria,237CB@1762|Mycobacteriaceae	201174|Actinobacteria	C	Protein of unknown function (DUF2855)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2855
PYH2_k127_194534_8	1131553.JIBI01000015_gene672	1.031e-82	288.0	COG2267@1|root,COG2267@2|Bacteria,1N2KV@1224|Proteobacteria	1224|Proteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH2_k127_194534_6	75379.Tint_2215	3.535e-103	343.0	COG0656@1|root,COG0656@2|Bacteria,1MUH2@1224|Proteobacteria,2VJNQ@28216|Betaproteobacteria,1KMZ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Aldo/keto reductase family	-	-	1.1.1.21	ko:K00011	ko00040,ko00051,ko00052,ko00561,ko00790,ko01100,map00040,map00051,map00052,map00561,map00790,map01100	-	R01036,R01041,R01093,R01095,R01431,R01758,R01759,R01787,R02531,R02577,R04285,R11764	RC00099,RC00108,RC00133,RC00205,RC00670	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
PYH2_k127_194534_0	987059.RBXJA2T_01710	0.0	1091.0	COG0480@1|root,COG0480@2|Bacteria,1MVVY@1224|Proteobacteria,2VKWB@28216|Betaproteobacteria,1KJI7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Elongation factor G, domain IV	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
PYH2_k127_194534_10	395495.Lcho_1716	7.807e-52	192.0	COG3350@1|root,COG3350@2|Bacteria,1PX0Q@1224|Proteobacteria,2W0V4@28216|Betaproteobacteria,1KNB3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_194534_4	316057.RPD_2831	1.424e-226	729.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,3JR79@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
PYH2_k127_194534_1	497321.C664_13744	1.267e-250	793.0	COG0775@1|root,COG0775@2|Bacteria,1MUMQ@1224|Proteobacteria,2VKRE@28216|Betaproteobacteria,2KXRE@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations	amn	-	3.2.2.4	ko:K01241	ko00230,map00230	-	R00182	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	AMNp_N,PNP_UDP_1
PYH2_k127_194534_2	864051.BurJ1DRAFT_0535	6.535e-241	760.0	COG0598@1|root,COG0598@2|Bacteria,1R7FC@1224|Proteobacteria,2VKBA@28216|Betaproteobacteria,1KK7V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Magnesium transport protein CorA	-	-	-	-	-	-	-	-	-	-	-	-	CorA
PYH2_k127_194534_3	1265502.KB905938_gene2419	1.637e-228	713.0	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2VH8B@28216|Betaproteobacteria,4ABQY@80864|Comamonadaceae	28216|Betaproteobacteria	I	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH2_k127_1945714_4	1265502.KB905932_gene1897	1.019e-45	168.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,4AA94@80864|Comamonadaceae	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
PYH2_k127_1945714_1	864051.BurJ1DRAFT_4442	7.692e-108	363.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,1KIT5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Displays ATPase and GTPase activities	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
PYH2_k127_1945714_2	420662.Mpe_A3337	9.66e-83	279.0	COG2802@1|root,COG2802@2|Bacteria,1RFYH@1224|Proteobacteria,2VSA4@28216|Betaproteobacteria,1KKT9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ATP-dependent protease La (LON) substrate-binding domain	-	-	-	ko:K07157	-	-	-	-	ko00000	-	-	-	LON_substr_bdg
PYH2_k127_1945714_0	987059.RBXJA2T_15558	1.278e-133	435.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,1KK6R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	TIGRFAM A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
PYH2_k127_1945714_3	420662.Mpe_A3234	1.113e-74	258.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,1KJS4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
PYH2_k127_1954449_4	420662.Mpe_A0308	6.582e-78	267.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,1KJNI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PYH2_k127_1954449_7	1286631.X805_14080	6.236e-53	191.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,1KM32@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
PYH2_k127_1954449_6	395495.Lcho_4236	1.579e-73	254.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,1KKMK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	hydrolase of the alpha beta superfamily	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Hydrolase_4,Thioesterase
PYH2_k127_1954449_1	987059.RBXJA2T_16247	3.145e-169	539.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,1KJ7B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PYH2_k127_1954449_2	1265502.KB905959_gene279	8.65e-142	454.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,4ACXI@80864|Comamonadaceae	28216|Betaproteobacteria	EH	Amino-transferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
PYH2_k127_1954449_8	987059.RBXJA2T_16237	4.408e-37	141.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,1KMC6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0250 family	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
PYH2_k127_1954449_3	1286631.X805_02280	4.405e-94	313.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,1KK26@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
PYH2_k127_1954449_0	1265502.KB905959_gene283	1.658e-176	557.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,4AAQD@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
PYH2_k127_1954449_5	420662.Mpe_A1033	3.4e-76	268.0	29AFQ@1|root,2ZXFW@2|Bacteria,1RGFB@1224|Proteobacteria,2VQD0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
PYH2_k127_1958553_5	395495.Lcho_0131	6.501e-52	193.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,1KJG0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PYH2_k127_1958553_4	864051.BurJ1DRAFT_0626	2.639e-97	325.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,1KK6N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
PYH2_k127_1958553_2	987059.RBXJA2T_17751	2.86e-117	400.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,1KJ10@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
PYH2_k127_1958553_1	987059.RBXJA2T_17756	9.228e-127	420.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,1KIUQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
PYH2_k127_1958553_3	987059.RBXJA2T_17761	8.413e-106	352.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,1KIZI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB_2	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
PYH2_k127_1958553_0	1095769.CAHF01000014_gene3013	4.917e-139	446.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,472RU@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
PYH2_k127_197195_3	395495.Lcho_0899	3.091e-36	141.0	COG0412@1|root,COG0412@2|Bacteria,1QVEZ@1224|Proteobacteria,2WH8H@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
PYH2_k127_197195_0	1288494.EBAPG3_20640	6.949e-163	524.0	COG1488@1|root,COG1488@2|Bacteria,1QRUH@1224|Proteobacteria,2W9XI@28216|Betaproteobacteria,372JT@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
PYH2_k127_197195_2	243233.MCA2761	5.853e-67	235.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,1RZBF@1236|Gammaproteobacteria,1XF7J@135618|Methylococcales	135618|Methylococcales	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
PYH2_k127_197195_1	338969.Rfer_0391	1.669e-123	405.0	COG2187@1|root,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,4AA57@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
PYH2_k127_1977258_0	1288494.EBAPG3_7510	1.052e-51	184.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,373EC@32003|Nitrosomonadales	28216|Betaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
PYH2_k127_1977258_1	1249627.D779_1335	1.796e-25	115.0	COG1073@1|root,COG1073@2|Bacteria,1RCSJ@1224|Proteobacteria,1S2PJ@1236|Gammaproteobacteria,1WY3V@135613|Chromatiales	135613|Chromatiales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_1977258_3	1144275.COCOR_04358	3.005e-11	76.0	COG2020@1|root,COG2020@2|Bacteria,1QTC1@1224|Proteobacteria,437VD@68525|delta/epsilon subdivisions,2X34Z@28221|Deltaproteobacteria,2Z1RR@29|Myxococcales	28221|Deltaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
PYH2_k127_1977258_4	66429.JOFL01000006_gene2072	0.0003332	53.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AATase,Condensation,FAD_binding_3
PYH2_k127_1977258_2	335543.Sfum_0593	2.874e-11	68.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42S7F@68525|delta/epsilon subdivisions,2WK0P@28221|Deltaproteobacteria,2MS10@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PYH2_k127_2000809_4	1054213.HMPREF9946_01182	1.156e-12	67.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TRH6@28211|Alphaproteobacteria,2JPTF@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_2000809_2	1231391.AMZF01000009_gene1748	2.967e-118	390.0	COG1173@1|root,COG1173@2|Bacteria,1MVER@1224|Proteobacteria,2VN73@28216|Betaproteobacteria,3T2JA@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH2_k127_2000809_0	1205680.CAKO01000040_gene991	1.931e-227	720.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQP0@28211|Alphaproteobacteria,2JPA1@204441|Rhodospirillales	204441|Rhodospirillales	P	COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH2_k127_2000809_1	196490.AUEZ01000074_gene7700	2.064e-182	584.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2TS1C@28211|Alphaproteobacteria,3JRKN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	MA20_32350	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
PYH2_k127_2000809_3	948106.AWZT01000015_gene758	1.961e-42	166.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VIRU@28216|Betaproteobacteria,1K2JD@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.5.1.1,4.3.1.12	ko:K01750,ko:K19743	ko00310,ko00330,ko00960,ko01100,ko01110,ko01130,ko01230,map00310,map00330,map00960,map01100,map01110,map01130,map01230	-	R00671,R01246,R01249,R02201,R02203	RC00135,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
PYH2_k127_2002316_1	987059.RBXJA2T_17996	2.574e-101	337.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2VJN4@28216|Betaproteobacteria,1KK89@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH2_k127_2002316_0	864051.BurJ1DRAFT_2937	1.981e-154	500.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2VH1D@28216|Betaproteobacteria,1KIW9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
PYH2_k127_2002316_3	864051.BurJ1DRAFT_2939	4.108e-14	79.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,1KNFB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TIGRFAM TRAP transporter, 4TM 12TM fusion protein	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH2_k127_2002316_2	296591.Bpro_2698	6.79e-25	108.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,4ABC8@80864|Comamonadaceae	28216|Betaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
PYH2_k127_2023464_0	983917.RGE_41090	1.077e-233	726.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,1KJ46@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PYH2_k127_2023464_3	987059.RBXJA2T_06420	2.787e-39	147.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,1KMBB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
PYH2_k127_2023464_2	1538295.JY96_02495	8.015e-105	346.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,1KJXH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	reductase	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_2023464_1	1538295.JY96_02500	3.032e-142	458.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,1KJRI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
PYH2_k127_2023464_4	1265502.KB905932_gene1839	2.654e-22	96.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,4AAUT@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
PYH2_k127_2027973_0	1123504.JQKD01000006_gene1458	9.05e-129	419.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,4AA51@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
PYH2_k127_2027973_3	382245.ASA_3294	3.692e-51	194.0	COG0457@1|root,COG0457@2|Bacteria,1P0WK@1224|Proteobacteria,1SU5D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
PYH2_k127_2027973_2	983917.RGE_00970	1.387e-96	323.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,1KJS2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
PYH2_k127_2027973_1	987059.RBXJA2T_05153	5.814e-126	411.0	COG3181@1|root,COG3181@2|Bacteria,1R7CA@1224|Proteobacteria,2VPK1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_2027973_4	987059.RBXJA2T_05143	2.2e-21	96.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2VITK@28216|Betaproteobacteria,1KJ8X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.3.8.7,1.5.5.2	ko:K00249,ko:K00294,ko:K13821	ko00071,ko00250,ko00280,ko00330,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00250,map00280,map00330,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00245,R00707,R00708,R00924,R01175,R01253,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04444,R04445,R04751,R04754,R05051	RC00052,RC00068,RC00076,RC00080,RC00083,RC00095,RC00148,RC00216,RC00242,RC00246,RC00255	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
PYH2_k127_2027973_6	1286631.X805_08000	1.265e-08	57.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2VITK@28216|Betaproteobacteria,1KJ8X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.3.8.7,1.5.5.2	ko:K00249,ko:K00294,ko:K13821	ko00071,ko00250,ko00280,ko00330,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00250,map00280,map00330,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00245,R00707,R00708,R00924,R01175,R01253,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04444,R04445,R04751,R04754,R05051	RC00052,RC00068,RC00076,RC00080,RC00083,RC00095,RC00148,RC00216,RC00242,RC00246,RC00255	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
PYH2_k127_2027973_5	1265502.KB905976_gene515	1.17e-19	99.0	COG1522@1|root,COG1522@2|Bacteria,1MX7R@1224|Proteobacteria,2VQBV@28216|Betaproteobacteria,4ADGR@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	lrp	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
PYH2_k127_2041344_1	318996.AXAZ01000008_gene4295	4.355e-30	124.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_2041344_0	189753.AXAS01000041_gene2534	7.793e-70	250.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_2041344_2	189753.AXAS01000011_gene7551	1.863e-08	59.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2URQN@28211|Alphaproteobacteria,3K6JB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
PYH2_k127_2053664_5	420662.Mpe_A0810	5.407e-23	104.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,1KJBE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_2053664_2	1265502.KB905933_gene2100	4.822e-100	333.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VIC3@28216|Betaproteobacteria,4ABFP@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Extradiol ring-cleavage dioxygenase, class III	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
PYH2_k127_2053664_4	243365.CV_0166	5.083e-42	174.0	COG1670@1|root,COG1670@2|Bacteria,1MVG4@1224|Proteobacteria,2VVMV@28216|Betaproteobacteria,2KSX5@206351|Neisseriales	206351|Neisseriales	J	Acetyltransferase (GNAT) domain	rimJ	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
PYH2_k127_2053664_1	983917.RGE_36580	1.11e-137	448.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,2VIVJ@28216|Betaproteobacteria,1KMWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
PYH2_k127_2053664_0	395495.Lcho_3742	5.189e-175	557.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2VI56@28216|Betaproteobacteria,1KKGG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	add	-	3.5.4.2	ko:K21053	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
PYH2_k127_2053664_3	420662.Mpe_A2184	7.589e-70	244.0	29SCQ@1|root,32R95@2|Bacteria,1RIT7@1224|Proteobacteria,2VSUG@28216|Betaproteobacteria,1KM4E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2053664_6	1078020.KEK_11713	0.0008146	43.0	2EZZU@1|root,33T3V@2|Bacteria,2GNV4@201174|Actinobacteria,233WD@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
PYH2_k127_2074064_7	864051.BurJ1DRAFT_4036	1.854e-64	226.0	COG1794@1|root,COG1794@2|Bacteria,1MW3C@1224|Proteobacteria,2VSWN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	racemase activity, acting on amino acids and derivatives	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2074064_2	365046.Rta_13480	1.454e-160	511.0	COG1638@1|root,COG1638@2|Bacteria,1MVYB@1224|Proteobacteria,2VIQ9@28216|Betaproteobacteria,4AA41@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP dicarboxylate transporter- DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH2_k127_2074064_6	1504672.669786649	7.235e-72	246.0	COG3090@1|root,COG3090@2|Bacteria,1N01Z@1224|Proteobacteria,2VRI7@28216|Betaproteobacteria,4ADWU@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH2_k127_2074064_1	1157708.KB907453_gene4207	2.657e-218	685.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VJME@28216|Betaproteobacteria,4AAMJ@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	siaT_7	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH2_k127_2074064_0	420662.Mpe_A2969	0.0	1059.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KJJ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
PYH2_k127_2074064_11	395495.Lcho_3840	1.557e-12	78.0	2EGTR@1|root,33AJW@2|Bacteria,1NN4K@1224|Proteobacteria,2VY7S@28216|Betaproteobacteria,1KMR0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2074064_8	358220.C380_19310	2.033e-48	188.0	COG2050@1|root,COG2050@2|Bacteria,1RHP8@1224|Proteobacteria,2VY16@28216|Betaproteobacteria,4AFY8@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH2_k127_2074064_3	1100720.ALKN01000045_gene462	3.879e-108	354.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,2VIBI@28216|Betaproteobacteria,4AE08@80864|Comamonadaceae	28216|Betaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PYH2_k127_2074064_4	365046.Rta_01670	5.154e-79	271.0	COG0697@1|root,COG0697@2|Bacteria,1MY34@1224|Proteobacteria,2VJYT@28216|Betaproteobacteria,4A9ZH@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_2074064_9	296591.Bpro_0196	2.22e-33	130.0	COG0697@1|root,COG0697@2|Bacteria,1MY34@1224|Proteobacteria,2VJYT@28216|Betaproteobacteria,4A9ZH@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_2074064_10	1538295.JY96_09440	2.832e-25	108.0	2EPRG@1|root,33HBY@2|Bacteria,1NQE6@1224|Proteobacteria,2VXYF@28216|Betaproteobacteria,1KP19@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2074064_12	1278078.G419_11911	5.121e-10	64.0	COG3865@1|root,COG3865@2|Bacteria,2IIAX@201174|Actinobacteria,4G18G@85025|Nocardiaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
PYH2_k127_2074064_5	1166948.JPZL01000003_gene480	5.883e-73	252.0	COG4122@1|root,COG4122@2|Bacteria,1N57D@1224|Proteobacteria,1S6JT@1236|Gammaproteobacteria,1XK1C@135619|Oceanospirillales	135619|Oceanospirillales	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
PYH2_k127_2082077_3	1211115.ALIQ01000089_gene4457	5.951e-12	72.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	puuC	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_2082077_0	983917.RGE_01770	1.689e-134	440.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VK1U@28216|Betaproteobacteria,1KN7E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_2082077_1	1100721.ALKO01000016_gene1458	4.759e-129	417.0	COG1173@1|root,COG1173@2|Bacteria,1MWMX@1224|Proteobacteria,2VIGP@28216|Betaproteobacteria,4AC6E@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH2_k127_2082077_2	1123504.JQKD01000018_gene2005	2.088e-121	408.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,4AA2A@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PYH2_k127_2082729_2	420662.Mpe_A0160	7.682e-129	420.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,1KMR3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PYH2_k127_2082729_3	1082933.MEA186_26491	1.258e-120	391.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,43NIW@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
PYH2_k127_2082729_8	381666.H16_A1812	3.288e-45	183.0	COG1917@1|root,COG1917@2|Bacteria,1PBNJ@1224|Proteobacteria,2VYV4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH2_k127_2082729_1	1380391.JIAS01000011_gene4709	1.693e-136	445.0	COG0477@1|root,COG2814@2|Bacteria,1MWFH@1224|Proteobacteria,2TR0R@28211|Alphaproteobacteria,2JR1G@204441|Rhodospirillales	204441|Rhodospirillales	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_2082729_9	1240349.ANGC01000049_gene3931	1.431e-26	112.0	COG4828@1|root,COG4828@2|Bacteria,2IQJ3@201174|Actinobacteria,4G1CM@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
PYH2_k127_2082729_6	1038859.AXAU01000003_gene5963	1.016e-52	209.0	COG3439@1|root,COG3439@2|Bacteria,1MZ38@1224|Proteobacteria,2U7V5@28211|Alphaproteobacteria,3JZAP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
PYH2_k127_2082729_0	1082933.MEA186_26496	8.231e-152	492.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2TS4V@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	esterase of the alpha-beta hydrolase superfamily	MA20_17270	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	DUF3734,Patatin
PYH2_k127_2082729_5	987059.RBXJA2T_05313	9.281e-57	204.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,1KKYT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Hemolysin III	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
PYH2_k127_2082729_4	570952.ATVH01000018_gene3245	1.378e-102	347.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2U23D@28211|Alphaproteobacteria,2JRHH@204441|Rhodospirillales	204441|Rhodospirillales	EH	Amino-transferase class IV	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_4
PYH2_k127_2082729_7	420662.Mpe_A3527	5.664e-52	184.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VK1C@28216|Betaproteobacteria,1KKI4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH2_k127_2090988_5	1458357.BG58_00215	4.845e-64	223.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,2VIH8@28216|Betaproteobacteria,1K37A@119060|Burkholderiaceae	28216|Betaproteobacteria	EH	d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding	ghrA	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C
PYH2_k127_2090988_2	1265502.KB905932_gene1910	4.991e-157	499.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VIUW@28216|Betaproteobacteria,4AAG8@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Pyruvate carboxyltransferase	hmgcL	GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
PYH2_k127_2090988_4	420662.Mpe_A3353	5.569e-70	254.0	COG2606@1|root,COG2606@2|Bacteria,1RD82@1224|Proteobacteria,2VQJW@28216|Betaproteobacteria,1KKV3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	YbaK prolyl-tRNA synthetase associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF1289,tRNA_edit
PYH2_k127_2090988_7	864051.BurJ1DRAFT_4735	2.215e-16	90.0	COG3313@1|root,COG3313@2|Bacteria,1NGD5@1224|Proteobacteria,2VXYJ@28216|Betaproteobacteria,1KMVN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
PYH2_k127_2090988_3	296591.Bpro_4153	9.006e-81	276.0	COG3917@1|root,COG3917@2|Bacteria,1RJFB@1224|Proteobacteria,2VPYN@28216|Betaproteobacteria,4ACDE@80864|Comamonadaceae	28216|Betaproteobacteria	Q	2-hydroxychromene-2-carboxylate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
PYH2_k127_2090988_1	977880.RALTA_A1103	9.337e-170	541.0	COG0500@1|root,COG0500@2|Bacteria,1N3PV@1224|Proteobacteria,2VK53@28216|Betaproteobacteria,1K6RR@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Putative methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
PYH2_k127_2090988_6	1504672.669784341	5.27e-42	160.0	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,2VTZZ@28216|Betaproteobacteria,4AEQT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
PYH2_k127_2090988_0	987059.RBXJA2T_03071	1.653e-303	945.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VHP4@28216|Betaproteobacteria,1KJE8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
PYH2_k127_2091262_4	929712.KI912613_gene3842	3.44e-20	92.0	COG0397@1|root,COG0397@2|Bacteria,2GNRX@201174|Actinobacteria,4CP7P@84995|Rubrobacteria	84995|Rubrobacteria	S	Uncharacterized ACR, YdiU/UPF0061 family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
PYH2_k127_2091262_5	1286106.MPL1_08444	6.072e-14	76.0	2D2Z4@1|root,32TDX@2|Bacteria,1MZK1@1224|Proteobacteria,1S9TU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
PYH2_k127_2091262_1	426117.M446_5605	1.266e-86	302.0	COG0329@1|root,COG0329@2|Bacteria,1RHIR@1224|Proteobacteria,2UAPH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EM	Dihydrodipicolinate synthetase family	-	-	-	-	-	-	-	-	-	-	-	-	DHDPS
PYH2_k127_2091262_0	864051.BurJ1DRAFT_4904	3.124e-128	421.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,2VJQG@28216|Betaproteobacteria,1KJCS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	PBP superfamily domain	tupB	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
PYH2_k127_2091262_3	987059.RBXJA2T_08300	2.884e-38	149.0	COG2839@1|root,COG2839@2|Bacteria,1MZEV@1224|Proteobacteria,2VSG8@28216|Betaproteobacteria,1KM6X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
PYH2_k127_2091262_2	477184.KYC_08850	2.25e-41	156.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2VMFS@28216|Betaproteobacteria,3T49Q@506|Alcaligenaceae	28216|Betaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
PYH2_k127_211437_5	522306.CAP2UW1_3355	1.671e-30	136.0	COG1396@1|root,COG1396@2|Bacteria,1R0QM@1224|Proteobacteria	1224|Proteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_211437_2	420662.Mpe_A1349	9.674e-101	351.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria,1KJ41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	ThiF family	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
PYH2_k127_211437_0	1265502.KB905929_gene2242	2.88e-156	504.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,4ABCJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
PYH2_k127_211437_1	378806.STAUR_1763	6.75e-107	358.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,43DXX@68525|delta/epsilon subdivisions,2X916@28221|Deltaproteobacteria,2Z1EC@29|Myxococcales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
PYH2_k127_211437_3	420662.Mpe_A1348	1.95e-92	310.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,1KK9M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
PYH2_k127_211437_4	1286631.X805_05780	1.599e-46	170.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,1KM0B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
PYH2_k127_2173131_1	1232410.KI421423_gene1911	3.816e-53	196.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
PYH2_k127_2173131_0	767817.Desgi_1127	5.984e-115	389.0	COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,261NS@186807|Peptococcaceae	186801|Clostridia	C	2-oxoacid ferredoxin oxidoreductase, alpha subunit	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
PYH2_k127_2185931_1	1305735.JAFT01000005_gene2518	2.077e-105	355.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,2TTVY@28211|Alphaproteobacteria,2PFDD@252301|Oceanicola	28211|Alphaproteobacteria	S	Flotillin	MA20_29840	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
PYH2_k127_2185931_4	1041139.KB902724_gene4151	1.4e-13	75.0	COG0625@1|root,COG0625@2|Bacteria,1RK1K@1224|Proteobacteria,2V5U1@28211|Alphaproteobacteria,4BGB5@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
PYH2_k127_2185931_3	279714.FuraDRAFT_1484	2.782e-17	83.0	COG0625@1|root,COG0625@2|Bacteria,1RK1K@1224|Proteobacteria,2WEV9@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N_3
PYH2_k127_2185931_5	472759.Nhal_0303	1.096e-11	68.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,1S1HV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH2_k127_2185931_0	420324.KI912045_gene4644	4.974e-162	516.0	COG0435@1|root,COG0435@2|Bacteria,1MV50@1224|Proteobacteria,2TRDE@28211|Alphaproteobacteria,1JT5Q@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yqjG	GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.8.5.7	ko:K07393	-	-	-	-	ko00000,ko01000	-	-	-	GST_C_2,GST_N_2
PYH2_k127_2185931_2	391624.OIHEL45_07835	1.145e-36	141.0	COG1171@1|root,COG1171@2|Bacteria,1MW2Q@1224|Proteobacteria,2TTP9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH2_k127_2207817_4	1286631.X805_30830	2.914e-18	98.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VQN2@28216|Betaproteobacteria,1KKP7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
PYH2_k127_2207817_1	983917.RGE_18490	5.212e-201	628.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,1KJTM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
PYH2_k127_2207817_2	1286631.X805_30790	6.684e-124	414.0	COG2267@1|root,COG2267@2|Bacteria,1QTAP@1224|Proteobacteria,2VMEV@28216|Betaproteobacteria,1KIZ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH2_k127_2207817_3	987059.RBXJA2T_05843	5.738e-71	244.0	COG0454@1|root,COG0456@2|Bacteria,1RCYQ@1224|Proteobacteria,2WGJZ@28216|Betaproteobacteria,1KMVM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PYH2_k127_2207817_0	1265502.KB905929_gene2205	6.031e-264	825.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJ5E@28216|Betaproteobacteria,4ACGG@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-binding enzyme	bclA_2	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_2207817_5	1268622.AVS7_02108	3.825e-14	85.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,2VR0I@28216|Betaproteobacteria,4AFQ2@80864|Comamonadaceae	28216|Betaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2224431_0	987059.RBXJA2T_10299	3.727e-279	872.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,1KPDE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	dppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH2_k127_2224431_1	1538295.JY96_20745	3.504e-43	158.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,1KJWA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_2233135_1	983917.RGE_15210	9.228e-16	79.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,1KM7T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0307 family	yjgA	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
PYH2_k127_2233135_0	1265502.KB905931_gene1677	8.76e-228	717.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,4ABC3@80864|Comamonadaceae	28216|Betaproteobacteria	S	peptidase U62, modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
PYH2_k127_2237191_3	420662.Mpe_A2223	3.196e-25	106.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,2VNEC@28216|Betaproteobacteria,1KK9T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	tupB	-	3.6.3.55	ko:K05773,ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
PYH2_k127_2237191_1	365044.Pnap_1340	9.269e-84	284.0	COG3548@1|root,COG3548@2|Bacteria,1R9WQ@1224|Proteobacteria,2VQBM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
PYH2_k127_2237191_0	296591.Bpro_1756	1.27e-164	531.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,4ABSP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
PYH2_k127_2237191_2	381666.H16_B0296	9.105e-39	149.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria,1K4MQ@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
PYH2_k127_2240951_2	1144325.PMI22_00633	1.855e-21	95.0	2EKK2@1|root,33E9Y@2|Bacteria,1N9Q2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2240951_1	323848.Nmul_A0501	5.759e-88	295.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria,37245@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
PYH2_k127_2240951_3	1173029.JH980292_gene2085	2.315e-10	70.0	COG0642@1|root,COG2199@1|root,COG2202@1|root,COG3829@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,COG3829@2|Bacteria,1FZWU@1117|Cyanobacteria,1H8MG@1150|Oscillatoriales	1117|Cyanobacteria	T	GGDEF domain'	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,GGDEF,PAS_3,PAS_4,PAS_8,PAS_9
PYH2_k127_2240951_0	983917.RGE_37700	3.785e-218	696.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria	28216|Betaproteobacteria	G	carbohydrate binding	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
PYH2_k127_2260896_1	1265502.KB905930_gene1534	1.815e-56	201.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,4ABQS@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
PYH2_k127_2260896_0	983917.RGE_28250	3.656e-270	837.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,1KIZK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
PYH2_k127_2264404_0	391735.Veis_0037	1.423e-173	549.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,4AAUE@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD4	-	4.2.1.25,4.2.1.82,4.2.1.9	ko:K01687,ko:K13875,ko:K22186	ko00040,ko00053,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00053,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R02522,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH2_k127_2264404_2	94624.Bpet4159	5.841e-114	379.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VMR0@28216|Betaproteobacteria,3T4AS@506|Alcaligenaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
PYH2_k127_2264404_1	1038860.AXAP01000088_gene3680	2.098e-146	473.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2TQY9@28211|Alphaproteobacteria,3JT9R@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH2_k127_2277505_9	1157708.KB907450_gene5954	1.372e-69	245.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VM00@28216|Betaproteobacteria,4ABHF@80864|Comamonadaceae	28216|Betaproteobacteria	S	Ankyrin repeats (3 copies)	-	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_4
PYH2_k127_2277505_3	864051.BurJ1DRAFT_4408	3.498e-163	520.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VHPP@28216|Betaproteobacteria,1KNBY@119065|unclassified Burkholderiales	1224|Proteobacteria	G	PFAM Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH2_k127_2277505_10	864051.BurJ1DRAFT_4407	7.271e-55	198.0	COG3090@1|root,COG3090@2|Bacteria,1NCEM@1224|Proteobacteria,2VYXV@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH2_k127_2277505_1	864051.BurJ1DRAFT_4406	1.428e-213	674.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,1KKA8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH2_k127_2277505_8	983917.RGE_43240	2.861e-90	301.0	COG2717@1|root,COG2717@2|Bacteria,1RDUP@1224|Proteobacteria,2VRBQ@28216|Betaproteobacteria,1KKD6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
PYH2_k127_2277505_2	1265502.KB905945_gene639	2.766e-167	530.0	COG2041@1|root,COG2041@2|Bacteria,1MUW0@1224|Proteobacteria,2VH08@28216|Betaproteobacteria,4A9NK@80864|Comamonadaceae	28216|Betaproteobacteria	C	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
PYH2_k127_2277505_11	864051.BurJ1DRAFT_4398	2.215e-36	142.0	2E4XG@1|root,32ZRD@2|Bacteria,1N79W@1224|Proteobacteria,2VWJP@28216|Betaproteobacteria,1KMGN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	tryptophan synthase subunit beta	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2277505_7	420662.Mpe_A0432	8.543e-92	306.0	COG2863@1|root,COG2863@2|Bacteria,1N2NB@1224|Proteobacteria,2VQNZ@28216|Betaproteobacteria,1KJQ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	cyc	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
PYH2_k127_2277505_6	395495.Lcho_0393	5.416e-95	319.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,1KJIR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
PYH2_k127_2277505_4	1265502.KB905945_gene633	2.167e-126	412.0	COG2267@1|root,COG2267@2|Bacteria,1QU7K@1224|Proteobacteria,2WH63@28216|Betaproteobacteria,4AJVY@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
PYH2_k127_2277505_5	395495.Lcho_1441	1.972e-104	345.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,1KKVY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Uroporphyrin-III C-methyltransferase	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
PYH2_k127_2277505_0	864051.BurJ1DRAFT_0681	3.404e-258	803.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,1KJI0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome D1 heme domain	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
PYH2_k127_2284553_10	864051.BurJ1DRAFT_3101	4.551e-48	175.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,1KMF0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
PYH2_k127_2284553_5	640081.Dsui_1472	3.284e-69	241.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,2KW52@206389|Rhodocyclales	206389|Rhodocyclales	F	Deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
PYH2_k127_2284553_3	420662.Mpe_A3016	5.137e-97	322.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,2VKF1@28216|Betaproteobacteria,1KK30@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
PYH2_k127_2284553_0	1286631.X805_11760	1.485e-165	537.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,1KJVK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
PYH2_k127_2284553_8	420662.Mpe_A1102	9.688e-58	204.0	COG2314@1|root,COG2314@2|Bacteria,1RD84@1224|Proteobacteria,2VSV6@28216|Betaproteobacteria,1KM5W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	TM2
PYH2_k127_2284553_7	983917.RGE_13460	8.551e-68	242.0	COG1247@1|root,COG1247@2|Bacteria,1RDHN@1224|Proteobacteria,2VQM1@28216|Betaproteobacteria,1KKW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
PYH2_k127_2284553_11	983917.RGE_13470	4.008e-35	136.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,1KM8E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
PYH2_k127_2284553_6	420662.Mpe_A1105	3.081e-68	240.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,1KKVJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
PYH2_k127_2284553_1	420662.Mpe_A1106	3.61e-107	353.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,1KJYY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
PYH2_k127_2284553_9	987059.RBXJA2T_05448	3.653e-56	203.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,1KKS7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
PYH2_k127_2284553_4	864051.BurJ1DRAFT_3092	4.593e-85	288.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,2VREV@28216|Betaproteobacteria,1KKNK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PYH2_k127_2284553_2	983917.RGE_13520	6.706e-104	347.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,1KJDN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
PYH2_k127_2289731_1	258594.RPA0678	2.54e-61	214.0	COG0493@1|root,COG0543@1|root,COG1633@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,COG1633@2|Bacteria,1MU2H@1224|Proteobacteria,2TSE2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
PYH2_k127_2289731_0	404589.Anae109_2748	3.379e-78	271.0	COG0493@1|root,COG0543@1|root,COG1633@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,COG1633@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	nfnA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
PYH2_k127_2289731_4	1385515.N791_13480	8.904e-22	97.0	2EFH4@1|root,3399Q@2|Bacteria,1N770@1224|Proteobacteria,1SUPF@1236|Gammaproteobacteria,1XBBJ@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2289731_2	1385515.N791_13475	2.139e-38	151.0	COG1569@1|root,COG1569@2|Bacteria,1MZXU@1224|Proteobacteria,1SRZC@1236|Gammaproteobacteria,1XB4A@135614|Xanthomonadales	135614|Xanthomonadales	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
PYH2_k127_2289731_3	504728.K649_10280	4.787e-28	118.0	COG0610@1|root,COG0610@2|Bacteria,1WJNG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Subunit R is required for both nuclease and ATPase activities, but not for modification	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF3387,HSDR_N,ResIII
PYH2_k127_2289731_5	419610.Mext_4265	4.358e-05	55.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2TR2M@28211|Alphaproteobacteria,1JRUR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
PYH2_k127_229001_1	296591.Bpro_4702	8.023e-147	467.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VK5V@28216|Betaproteobacteria,4AAPR@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
PYH2_k127_229001_4	296591.Bpro_4703	4.171e-80	272.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,4AAAK@80864|Comamonadaceae	28216|Betaproteobacteria	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD
PYH2_k127_229001_0	1123355.JHYO01000023_gene2360	2.027e-197	629.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2TUDG@28211|Alphaproteobacteria,36Z6S@31993|Methylocystaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_229001_5	1095769.CAHF01000011_gene2150	6.424e-72	255.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2W0Q4@28216|Betaproteobacteria,473QQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	pbpG1	-	3.4.16.4	ko:K01286,ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
PYH2_k127_229001_3	395495.Lcho_4378	4.643e-107	354.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VQD1@28216|Betaproteobacteria,1KKUH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
PYH2_k127_229001_2	381666.H16_B1765	5.939e-146	471.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VHC1@28216|Betaproteobacteria,1K09M@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	1.16.1.1	ko:K00520,ko:K21739	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
PYH2_k127_2330242_0	420662.Mpe_A3356	8.204e-228	713.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,1KJWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	carboxylase	accA1	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
PYH2_k127_2330242_1	864051.BurJ1DRAFT_4739	4.885e-26	109.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,2VRVF@28216|Betaproteobacteria,1KKSB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
PYH2_k127_2334751_3	864051.BurJ1DRAFT_1388	4.024e-35	134.0	COG0832@1|root,COG0832@2|Bacteria,1RGW0@1224|Proteobacteria,2VSGJ@28216|Betaproteobacteria,1KM42@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta
PYH2_k127_2334751_0	395495.Lcho_1076	0.0	1013.0	COG0804@1|root,COG0804@2|Bacteria,1MU5P@1224|Proteobacteria,2VJYX@28216|Betaproteobacteria,1KK4I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
PYH2_k127_2334751_2	296591.Bpro_1277	7.176e-63	223.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VR6K@28216|Betaproteobacteria,4AHIQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
PYH2_k127_2334751_1	1286631.X805_11260	7.31e-67	243.0	COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,2VMRF@28216|Betaproteobacteria,1KJ8W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
PYH2_k127_2391254_2	595537.Varpa_2525	1.288e-33	134.0	COG1225@1|root,COG1225@2|Bacteria,1RHSM@1224|Proteobacteria,2VQNM@28216|Betaproteobacteria,4AEPY@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp_2	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
PYH2_k127_2391254_0	864051.BurJ1DRAFT_0529	1.1e-101	344.0	COG2014@1|root,COG2014@2|Bacteria,1MV5Z@1224|Proteobacteria,2VPCD@28216|Betaproteobacteria,1KM4B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative heavy-metal chelation	-	-	-	-	-	-	-	-	-	-	-	-	DUF364,DUF4213
PYH2_k127_2391254_1	864051.BurJ1DRAFT_4758	2.12e-39	151.0	COG0011@1|root,COG0011@2|Bacteria,1N0UT@1224|Proteobacteria,2VW0K@28216|Betaproteobacteria,1KNWA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
PYH2_k127_2391254_3	864051.BurJ1DRAFT_4759	1.598e-12	69.0	COG0095@1|root,COG0095@2|Bacteria,1MZGC@1224|Proteobacteria,2VQIA@28216|Betaproteobacteria,1KNIZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	lipoate-protein ligase A	-	-	-	-	-	-	-	-	-	-	-	-	BPL_LplA_LipB
PYH2_k127_2461793_5	1211777.BN77_1472	3.768e-25	109.0	2ESJH@1|root,33K45@2|Bacteria,1PXP4@1224|Proteobacteria,2V0GG@28211|Alphaproteobacteria,4BGM9@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
PYH2_k127_2461793_3	1380355.JNIJ01000023_gene2439	6.715e-178	565.0	COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,2TVAP@28211|Alphaproteobacteria,3JRAG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
PYH2_k127_2461793_0	1419583.V466_02355	1.312e-299	927.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,1SYC8@1236|Gammaproteobacteria,1YS5T@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	Sulfate permease family	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
PYH2_k127_2461793_4	1125973.JNLC01000016_gene2720	1.341e-151	485.0	COG0549@1|root,COG0549@2|Bacteria,1MWXC@1224|Proteobacteria,2TVMD@28211|Alphaproteobacteria,3JXQB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PYH2_k127_2461793_2	1246459.KB898353_gene542	2.269e-192	603.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2TUZN@28211|Alphaproteobacteria,4B8VT@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3,2.1.3.6	ko:K00611,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
PYH2_k127_2461793_1	1033991.RLEG12_27105	1.681e-202	637.0	COG2235@1|root,COG2235@2|Bacteria,1NCGV@1224|Proteobacteria,2TU0Z@28211|Alphaproteobacteria,4BAQ4@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Arginine	arcA	-	3.5.3.6	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	-	R00552	RC00177	ko00000,ko00001,ko01000	-	-	-	Amidinotransf
PYH2_k127_2461793_6	1246459.KB898353_gene549	2.404e-23	104.0	COG0834@1|root,COG0834@2|Bacteria,1RD36@1224|Proteobacteria,2USIJ@28211|Alphaproteobacteria,4BMC8@82115|Rhizobiaceae	28211|Alphaproteobacteria	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PYH2_k127_2464617_0	983917.RGE_15540	9.495e-148	473.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VHCB@28216|Betaproteobacteria,1KJ1A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NAD(P)H quinone oxidoreductase, PIG3 family	qor1	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_2464617_1	395495.Lcho_1499	5.658e-120	394.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,1KK1K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
PYH2_k127_2464617_2	535289.Dtpsy_0871	1.09e-31	126.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,4AEHQ@80864|Comamonadaceae	28216|Betaproteobacteria	U	PFAM Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
PYH2_k127_2467449_0	1545915.JROG01000003_gene778	2.068e-42	173.0	COG0515@1|root,3345A@2|Bacteria,1NSRF@1224|Proteobacteria	1224|Proteobacteria	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2467449_1	479432.Sros_5419	2.068e-05	48.0	COG0654@1|root,COG0654@2|Bacteria,2GIZU@201174|Actinobacteria,4EJ7S@85012|Streptosporangiales	201174|Actinobacteria	CH	FAD binding domain	-	-	1.14.13.1	ko:K00480	ko00621,ko00624,ko00626,ko01100,ko01120,ko01220,map00621,map00624,map00626,map01100,map01120,map01220	-	R00818,R05632,R06915,R06936,R06939	RC00389	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
PYH2_k127_2482388_5	748247.AZKH_p0408	2.989e-50	200.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHAU@28216|Betaproteobacteria,2KWHB@206389|Rhodocyclales	206389|Rhodocyclales	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,Pkinase
PYH2_k127_2482388_6	983917.RGE_32560	3.754e-23	111.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2VVSP@28216|Betaproteobacteria,1KMNH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
PYH2_k127_2482388_3	266264.Rmet_1964	9.994e-167	533.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,2VIFK@28216|Betaproteobacteria,1JZXP@119060|Burkholderiaceae	28216|Betaproteobacteria	H	MoeA domain protein domain I and II	moeA1	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
PYH2_k127_2482388_4	420662.Mpe_A1543	2.607e-72	254.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,1KKZZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
PYH2_k127_2482388_0	420662.Mpe_A1542	4.316e-237	741.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,1KK4V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
PYH2_k127_2482388_1	987059.RBXJA2T_19561	2.431e-227	710.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,1KJ3I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
PYH2_k127_2482388_2	864051.BurJ1DRAFT_2493	2.67e-192	602.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,1KJTU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM Aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH2_k127_2496436_2	983917.RGE_43720	6.339e-166	529.0	COG3170@1|root,COG3170@2|Bacteria,1QXJ7@1224|Proteobacteria,2WH5D@28216|Betaproteobacteria,1KKAA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
PYH2_k127_2496436_4	420662.Mpe_A3389	2.374e-91	303.0	COG5405@1|root,COG5405@2|Bacteria,1MVF2@1224|Proteobacteria,2VIFV@28216|Betaproteobacteria,1KJHV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery	hslV	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
PYH2_k127_2496436_1	864051.BurJ1DRAFT_0496	6.581e-218	686.0	COG1220@1|root,COG1220@2|Bacteria,1MVK9@1224|Proteobacteria,2VHG3@28216|Betaproteobacteria,1KK09@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis	hslU	-	-	ko:K03667	-	-	-	-	ko00000,ko03110	-	-	-	AAA_2,ClpB_D2-small
PYH2_k127_2496436_3	983917.RGE_43750	1.613e-115	383.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,1KJ92@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
PYH2_k127_2496436_5	420662.Mpe_A3392	2.932e-15	88.0	2EGTR@1|root,33AJW@2|Bacteria,1NN4K@1224|Proteobacteria,2VY7S@28216|Betaproteobacteria,1KMR0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2496436_0	420662.Mpe_A0903	2.983e-241	754.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,1KJWN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
PYH2_k127_2518735_0	983917.RGE_29110	1.208e-200	630.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2VJUV@28216|Betaproteobacteria,1KK55@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
PYH2_k127_2518735_1	420662.Mpe_A1940	2.412e-197	620.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,1KJ43@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_2526785_3	864051.BurJ1DRAFT_3519	1.082e-112	368.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,1KJI4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
PYH2_k127_2526785_8	1122604.JONR01000006_gene2513	1.236e-27	126.0	COG0454@1|root,COG0456@2|Bacteria,1NCMN@1224|Proteobacteria,1SFS0@1236|Gammaproteobacteria,1X7VK@135614|Xanthomonadales	135614|Xanthomonadales	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
PYH2_k127_2526785_2	379066.GAU_3811	2.042e-137	447.0	COG0665@1|root,COG0665@2|Bacteria,1ZUJW@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
PYH2_k127_2526785_6	857087.Metme_0429	6.198e-49	179.0	COG2337@1|root,COG2337@2|Bacteria,1PVJ9@1224|Proteobacteria,1TM47@1236|Gammaproteobacteria,1XGTH@135618|Methylococcales	135618|Methylococcales	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
PYH2_k127_2526785_9	443144.GM21_2584	5.833e-25	113.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	mazE	-	-	ko:K07172,ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
PYH2_k127_2526785_5	420662.Mpe_A3047	3.493e-75	254.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,1KKU6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
PYH2_k127_2526785_0	420662.Mpe_A3046	0.0	1591.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,1KJY8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
PYH2_k127_2526785_1	1265502.KB905964_gene1391	3.171e-150	496.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,4AAKA@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
PYH2_k127_2526785_4	296591.Bpro_5567	1.829e-109	369.0	COG3284@1|root,COG3284@2|Bacteria,1Q5BU@1224|Proteobacteria,2VJEK@28216|Betaproteobacteria,4ABK7@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM helix-turn-helix, Fis-type	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8
PYH2_k127_2526785_7	864051.BurJ1DRAFT_3857	2.586e-35	138.0	COG3191@1|root,COG3191@2|Bacteria,1MWDP@1224|Proteobacteria,2VHM1@28216|Betaproteobacteria,1KN3S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EQ	Peptidase family S58	-	-	3.4.11.19	ko:K01266	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S58
PYH2_k127_2530937_9	420662.Mpe_A0167	8.666e-25	112.0	COG2885@1|root,COG2885@2|Bacteria,1NJYE@1224|Proteobacteria,2VXMF@28216|Betaproteobacteria,1KMUG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2530937_2	864051.BurJ1DRAFT_0281	8.773e-181	570.0	COG0646@1|root,COG0646@2|Bacteria,1NPFY@1224|Proteobacteria,2VJ2K@28216|Betaproteobacteria,1KJQA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	homocysteine S-methyltransferase	metHa	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
PYH2_k127_2530937_1	614083.AWQR01000033_gene2867	1.141e-202	653.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4ACAD@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	gmr	-	2.7.7.65	ko:K21023	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,MHYT
PYH2_k127_2530937_0	864051.BurJ1DRAFT_0280	0.0	1153.0	COG0464@1|root,COG0464@2|Bacteria,1NF48@1224|Proteobacteria,2VK2M@28216|Betaproteobacteria,1KKCB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
PYH2_k127_2530937_8	1265502.KB905968_gene1250	3.384e-26	111.0	2E6W9@1|root,32SGN@2|Bacteria,1MZMD@1224|Proteobacteria,2VU0A@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3567)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3567
PYH2_k127_2530937_6	864051.BurJ1DRAFT_0278	7.132e-48	185.0	2DN7F@1|root,32VYA@2|Bacteria,1QUZI@1224|Proteobacteria,2VUAZ@28216|Betaproteobacteria,1KMCG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
PYH2_k127_2530937_3	596153.Alide_0519	2.439e-168	541.0	COG0179@1|root,COG0179@2|Bacteria,1MV0V@1224|Proteobacteria,2VGZX@28216|Betaproteobacteria,4AA6Y@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Fumarylacetoacetate (Faa) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
PYH2_k127_2530937_7	420662.Mpe_A3634	1.564e-47	175.0	COG3577@1|root,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	orf	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
PYH2_k127_2530937_4	580332.Slit_1241	5.638e-78	271.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2VQAJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM GumN family protein	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
PYH2_k127_2530937_5	864051.BurJ1DRAFT_4539	1.251e-61	220.0	2EDY7@1|root,30V4M@2|Bacteria,1RGIS@1224|Proteobacteria,2VQT2@28216|Betaproteobacteria,1KKZ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2531683_2	1286631.X805_31680	4.354e-40	166.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,1KKQR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_2531683_1	864051.BurJ1DRAFT_4850	1.172e-158	507.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHHP@28216|Betaproteobacteria,1KIZR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_2531683_0	864051.BurJ1DRAFT_4851	3.41e-198	626.0	COG1593@1|root,COG1593@2|Bacteria,1MUQE@1224|Proteobacteria,2VHK0@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Malonyl-CoA decarboxylase	matA	-	4.1.1.9	ko:K01578	ko00410,ko00640,ko01100,ko04146,ko04152,map00410,map00640,map01100,map04146,map04152	-	R00233	RC00040	ko00000,ko00001,ko01000	-	-	-	MCD,MCD_N
PYH2_k127_2531683_4	864051.BurJ1DRAFT_4853	4.903e-10	67.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2WGSI@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
PYH2_k127_2531683_3	522306.CAP2UW1_3522	3.213e-29	120.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2W9C4@28216|Betaproteobacteria,1KQ5B@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
PYH2_k127_2531683_5	426117.M446_0987	0.000601	43.0	COG3791@1|root,COG3791@2|Bacteria,1N0W7@1224|Proteobacteria,2VGCF@28211|Alphaproteobacteria,1JZEX@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
PYH2_k127_2533508_1	296591.Bpro_4697	5.608e-191	601.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VKXZ@28216|Betaproteobacteria,4A9K4@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily	phnW	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
PYH2_k127_2533508_4	6500.XP_005099940.1	3.193e-74	261.0	COG0637@1|root,2QU58@2759|Eukaryota,39WII@33154|Opisthokonta,3BF9K@33208|Metazoa,3D4RC@33213|Bilateria	33208|Metazoa	S	Haloacid dehalogenase-like hydrolase	-	-	3.11.1.1	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747	RC00368	ko00000,ko00001,ko01000	-	-	-	HAD_2
PYH2_k127_2533508_0	296591.Bpro_4698	2.576e-253	786.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2WFJM@28216|Betaproteobacteria,4AD19@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C
PYH2_k127_2533508_2	296591.Bpro_4700	4.021e-174	593.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,4AD0R@80864|Comamonadaceae	28216|Betaproteobacteria	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
PYH2_k127_2533508_3	987059.RBXJA2T_15158	4.441e-116	381.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,2VMMI@28216|Betaproteobacteria,1KK6K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase C26	-	-	4.1.3.27	ko:K01658,ko:K07010	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	Peptidase_C26
PYH2_k127_2533508_5	296591.Bpro_4702	1.324e-70	252.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VK5V@28216|Betaproteobacteria,4AAPR@80864|Comamonadaceae	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
PYH2_k127_253399_1	648757.Rvan_0038	1.228e-62	223.0	COG1775@1|root,COG1775@2|Bacteria,1NKED@1224|Proteobacteria,2U31W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	benzoyl-CoA reductase	-	-	1.3.7.8	ko:K04113	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
PYH2_k127_253399_0	1232410.KI421421_gene3270	5.44e-172	545.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42RTN@68525|delta/epsilon subdivisions,2WNYI@28221|Deltaproteobacteria,43V0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	1.3.7.8	ko:K04112	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	HGD-D
PYH2_k127_2534904_2	395495.Lcho_1955	4.062e-55	196.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,2VSQW@28216|Betaproteobacteria,1KNPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
PYH2_k127_2534904_3	864051.BurJ1DRAFT_3783	1.047e-38	153.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria,1KM69@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
PYH2_k127_2534904_4	391735.Veis_4250	1.337e-32	128.0	COG1917@1|root,COG1917@2|Bacteria,1N7QJ@1224|Proteobacteria,2VVHY@28216|Betaproteobacteria,4AFEU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin 2, conserved barrel	-	-	-	ko:K21700	-	-	-	-	ko00000	-	-	-	Cupin_2
PYH2_k127_2534904_1	1123247.AUIJ01000008_gene2598	6.518e-112	377.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2TV15@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440,ko:K17203	ko02010,map02010	M00212,M00590	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19	-	-	BPD_transp_2
PYH2_k127_2534904_0	570952.ATVH01000015_gene1451	2.462e-163	528.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,2JPHE@204441|Rhodospirillales	204441|Rhodospirillales	G	Monosaccharide ABC transporter ATP-binding protein, CUT2 family	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
PYH2_k127_253867_1	1286631.X805_12520	3.799e-70	250.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,1KK3D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
PYH2_k127_253867_2	864051.BurJ1DRAFT_2674	5.227e-61	214.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,1KKVV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
PYH2_k127_253867_0	1265502.KB905930_gene1534	1.669e-178	562.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,4ABQS@80864|Comamonadaceae	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
PYH2_k127_2561127_0	420662.Mpe_A1076	5.101e-143	466.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,1KJ2Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TonB dependent receptor	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH2_k127_2561127_1	1123229.AUBC01000029_gene3527	3.682e-31	128.0	COG4448@1|root,COG4448@2|Bacteria,1R4NH@1224|Proteobacteria,2TV9J@28211|Alphaproteobacteria,3K2GD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	L-asparaginase II	ansA	-	-	-	-	-	-	-	-	-	-	-	Asparaginase_II
PYH2_k127_2561989_2	420662.Mpe_A1128	5.57e-55	196.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,1KJMQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	epimerase dehydratase	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
PYH2_k127_2561989_0	864051.BurJ1DRAFT_1708	2.369e-114	378.0	COG0265@1|root,COG0265@2|Bacteria,1MURF@1224|Proteobacteria,2VPCV@28216|Betaproteobacteria,1KKFB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
PYH2_k127_2561989_1	420662.Mpe_A1130	1.041e-93	314.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,2VQB1@28216|Betaproteobacteria,1KKR5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Eukaryotic integral membrane protein (DUF1751)	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
PYH2_k127_2561989_3	420662.Mpe_A1087	2.199e-07	52.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,2VHG5@28216|Betaproteobacteria,1KIZF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
PYH2_k127_2567072_1	686340.Metal_0856	6.585e-37	145.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1XDTX@135618|Methylococcales	135618|Methylococcales	M	family 9	-	-	-	ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
PYH2_k127_2567072_0	1265502.KB905929_gene2237	5.434e-256	802.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,4AA30@80864|Comamonadaceae	28216|Betaproteobacteria	J	ribonuclease, Rne Rng family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
PYH2_k127_2567072_2	543728.Vapar_2689	5.919e-32	126.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,4ADGX@80864|Comamonadaceae	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
PYH2_k127_2587499_5	1223521.BBJX01000001_gene998	4.076e-11	68.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,2VHP8@28216|Betaproteobacteria,4AB89@80864|Comamonadaceae	28216|Betaproteobacteria	K	COG1522 Transcriptional regulators	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
PYH2_k127_2587499_1	1538295.JY96_19625	1.699e-198	628.0	COG3391@1|root,COG3391@2|Bacteria,1QD5Q@1224|Proteobacteria,2VH1W@28216|Betaproteobacteria,1KK46@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cytochrome D1 heme domain	nirF	-	-	ko:K19345	-	-	-	-	ko00000	-	-	-	Cytochrom_D1
PYH2_k127_2587499_3	395495.Lcho_1443	1.881e-38	146.0	COG2010@1|root,COG2010@2|Bacteria,1N73U@1224|Proteobacteria,2VTXS@28216|Betaproteobacteria,1KMDM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	nirC	-	-	ko:K19344	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
PYH2_k127_2587499_4	1538295.JY96_19635	4.247e-34	134.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,1KNZU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
PYH2_k127_2587499_0	76114.ebA888	6.071e-317	978.0	COG2010@1|root,COG2010@2|Bacteria,1N3PN@1224|Proteobacteria,2VHSF@28216|Betaproteobacteria,2KVT2@206389|Rhodocyclales	206389|Rhodocyclales	C	Cytochrome D1 heme domain	nirS	-	1.7.2.1,1.7.99.1	ko:K15864	ko00910,ko01120,map00910,map01120	M00529	R00143,R00783,R00785	RC00086,RC02797	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_D1,Cytochrome_CBB3
PYH2_k127_2587499_2	580332.Slit_1672	5.072e-96	323.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,44V38@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
PYH2_k127_2596477_0	983917.RGE_14260	5.762e-66	237.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2VQ14@28216|Betaproteobacteria,1KKMA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Pseudouridine synthase	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
PYH2_k127_2596477_2	1265502.KB905929_gene2216	5.73e-42	160.0	COG2453@1|root,COG2453@2|Bacteria,1NDVQ@1224|Proteobacteria,2VWYX@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
PYH2_k127_2596477_1	1538295.JY96_05865	8.709e-54	192.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,1KKAD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	import inner membrane translocase subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
PYH2_k127_2639565_8	864051.BurJ1DRAFT_2720	4.271e-92	305.0	COG0664@1|root,COG0664@2|Bacteria,1RE4X@1224|Proteobacteria,2VMCY@28216|Betaproteobacteria,1KK4E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_2639565_5	1265502.KB905930_gene1503	7.117e-177	559.0	COG3173@1|root,COG3173@2|Bacteria,1MWAK@1224|Proteobacteria,2VJ31@28216|Betaproteobacteria,4A9R4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
PYH2_k127_2639565_2	420662.Mpe_A1953	2.257e-231	725.0	COG1960@1|root,COG1960@2|Bacteria,1MU2V@1224|Proteobacteria,2VI1V@28216|Betaproteobacteria,1KK5Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_2639565_11	987059.RBXJA2T_03466	7.075e-44	169.0	2ECFI@1|root,336DT@2|Bacteria,1NBHQ@1224|Proteobacteria,2VW1X@28216|Betaproteobacteria,1KMKQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2639565_7	1265502.KB905930_gene1501	4.784e-130	419.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,4ACDR@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the GST superfamily	gstI	-	2.5.1.18	ko:K00799,ko:K11209	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_2
PYH2_k127_2639565_14	391615.ABSJ01000002_gene467	1.348e-09	69.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2639565_9	983917.RGE_32350	4.976e-70	240.0	COG3597@1|root,COG3597@2|Bacteria,1RKKI@1224|Proteobacteria,2VU6W@28216|Betaproteobacteria,1KMJH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	protein domain associated with	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2639565_12	864051.BurJ1DRAFT_2887	5.784e-29	119.0	COG2261@1|root,COG2261@2|Bacteria,1N72W@1224|Proteobacteria,2VVXU@28216|Betaproteobacteria,1KMM2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
PYH2_k127_2639565_0	1265502.KB905930_gene1499	0.0	1897.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,4AA2Y@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM ATP-dependent helicase HrpA	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
PYH2_k127_2639565_1	395495.Lcho_2228	1.157e-259	804.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,1KJ7S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
PYH2_k127_2639565_10	987059.RBXJA2T_01425	7.414e-45	166.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,1KM13@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
PYH2_k127_2639565_6	420662.Mpe_A1371	2.799e-163	520.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,2VHI6@28216|Betaproteobacteria,1KK62@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type Fe3 transport system, periplasmic component	fbpA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
PYH2_k127_2639565_13	864051.BurJ1DRAFT_2894	7.933e-29	119.0	COG2916@1|root,COG2916@2|Bacteria,1N7YA@1224|Proteobacteria,2VW5J@28216|Betaproteobacteria,1KM8S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Histone family protein nucleoid-structuring protein H-NS	-	-	-	ko:K03746	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	Histone_HNS
PYH2_k127_2639565_3	864051.BurJ1DRAFT_2895	8.443e-209	674.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJEE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CZB,Cache_3-Cache_2,EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Response_reg
PYH2_k127_2639565_4	420662.Mpe_A2490	1.177e-204	645.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,1KK4K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
PYH2_k127_2643080_3	1037409.BJ6T_87360	2.041e-29	125.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_2643080_1	296591.Bpro_2748	8.716e-82	277.0	COG0500@1|root,COG2226@2|Bacteria,1MZVH@1224|Proteobacteria,2VZ2M@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
PYH2_k127_2643080_0	983917.RGE_36130	5.958e-85	286.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,2VSZI@28216|Betaproteobacteria,1KMJD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
PYH2_k127_265794_2	864051.BurJ1DRAFT_4716	2.104e-52	201.0	COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,2VMDP@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_4
PYH2_k127_265794_1	864051.BurJ1DRAFT_4718	3.449e-98	330.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,2VI3C@28216|Betaproteobacteria,1KNA0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PYH2_k127_265794_0	296591.Bpro_1491	3.039e-110	364.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2VN5A@28216|Betaproteobacteria,4AC1W@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.401	ko:K21883	ko00051,ko01120,map00051,map01120	-	R11339	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
PYH2_k127_265794_3	595537.Varpa_5382	6.392e-23	99.0	COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,2VHGA@28216|Betaproteobacteria,4AASB@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.410	ko:K22025	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
PYH2_k127_2712108_0	748280.NH8B_0065	2.109e-301	948.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VIAP@28216|Betaproteobacteria,2KPJQ@206351|Neisseriales	206351|Neisseriales	V	ABC transporter, ATP-binding protein	-	-	-	ko:K18893	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
PYH2_k127_2712108_2	420324.KI912086_gene7356	2.662e-93	311.0	COG1225@1|root,COG1225@2|Bacteria,1N86B@1224|Proteobacteria,2TVN1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
PYH2_k127_2712108_1	420324.KI912086_gene7355	8.337e-102	335.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,1JR57@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
PYH2_k127_2723708_0	864051.BurJ1DRAFT_2881	1.608e-62	230.0	28JVP@1|root,2Z9KK@2|Bacteria,1R4DG@1224|Proteobacteria,2VPKF@28216|Betaproteobacteria,1KKJP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2723708_2	365044.Pnap_3341	4.317e-38	153.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PYH2_k127_2723708_1	1380356.JNIK01000001_gene2131	4.227e-47	175.0	COG1309@1|root,COG1309@2|Bacteria,2GTS6@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PYH2_k127_2731961_3	748247.AZKH_2902	8.71e-14	75.0	COG3302@1|root,COG3302@2|Bacteria,1R64Q@1224|Proteobacteria,2VNSS@28216|Betaproteobacteria,2KVPW@206389|Rhodocyclales	206389|Rhodocyclales	S	DMSO reductase anchor subunit (DmsC)	padD	-	-	ko:K18363	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	DmsC
PYH2_k127_2731961_1	316056.RPC_0698	1.645e-198	633.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,3K64X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
PYH2_k127_2731961_2	748247.AZKH_0491	2.126e-66	234.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ75@28216|Betaproteobacteria,2KW1Q@206389|Rhodocyclales	206389|Rhodocyclales	C	[2Fe-2S] binding domain	hcrC	-	1.3.7.9	ko:K04107	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316	RC00490	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_2731961_0	316057.RPD_1524	1.63e-315	983.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria,3JQT8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.2.5.3,1.3.7.9	ko:K03520,ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316,R11168	RC00490,RC02800	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
PYH2_k127_2731961_4	1244869.H261_04862	2.996e-09	64.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,2TRAR@28211|Alphaproteobacteria,2JRX7@204441|Rhodospirillales	204441|Rhodospirillales	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.17.1.4	ko:K11178	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH2_k127_2742097_0	365046.Rta_33910	1.648e-153	494.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,4ABBZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
PYH2_k127_2742097_1	1110502.TMO_3118	4.593e-55	205.0	COG2114@1|root,COG2114@2|Bacteria,1MVZU@1224|Proteobacteria,2U128@28211|Alphaproteobacteria,2JWF3@204441|Rhodospirillales	204441|Rhodospirillales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
PYH2_k127_274215_0	864051.BurJ1DRAFT_2848	5.42e-197	616.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,1KJ90@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
PYH2_k127_274215_2	864051.BurJ1DRAFT_2852	2.56e-174	553.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHEJ@28216|Betaproteobacteria,1KKFY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
PYH2_k127_274215_1	864051.BurJ1DRAFT_2853	4.521e-192	606.0	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2VICQ@28216|Betaproteobacteria,1KKHZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding protein	potD	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
PYH2_k127_274215_3	1286631.X805_06270	1.006e-14	76.0	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2VK8I@28216|Betaproteobacteria,1KJ2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
PYH2_k127_2772617_2	875328.JDM601_2174	4.582e-45	183.0	COG1024@1|root,COG1024@2|Bacteria,2H2U8@201174|Actinobacteria,23AUU@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH2_k127_2772617_1	1110502.TMO_2422	1.252e-117	389.0	COG1024@1|root,COG1024@2|Bacteria,1PK10@1224|Proteobacteria,2TS4M@28211|Alphaproteobacteria,2JW6C@204441|Rhodospirillales	204441|Rhodospirillales	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH2_k127_2772617_3	522306.CAP2UW1_0718	4.887e-27	113.0	COG2361@1|root,COG2361@2|Bacteria,1N6ZA@1224|Proteobacteria,2VTQB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
PYH2_k127_2772617_0	1100720.ALKN01000007_gene3056	8.017e-149	476.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VJ7Q@28216|Betaproteobacteria,4AC45@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_2803460_0	29486.NJ56_05200	2.058e-285	916.0	COG0642@1|root,COG3614@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,COG3614@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,41ENI@629|Yersinia	1236|Gammaproteobacteria	T	Uncharacterised signal transduction histidine kinase domain (DUF2222)	barA	-	2.7.13.3	ko:K07678	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	M00475	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,DUF2222,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
PYH2_k127_2803460_2	614083.AWQR01000047_gene3310	7.872e-140	458.0	COG3917@1|root,COG3917@2|Bacteria,1MV6E@1224|Proteobacteria,2W52I@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
PYH2_k127_2803460_4	395495.Lcho_1324	2.175e-37	141.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,2VWXC@28216|Betaproteobacteria,1KMTG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
PYH2_k127_2803460_1	395495.Lcho_1323	1.349e-232	727.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,2VNTF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
PYH2_k127_2803460_3	420662.Mpe_A1426	1.488e-41	157.0	COG1917@1|root,COG1917@2|Bacteria,1RJ04@1224|Proteobacteria	1224|Proteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH2_k127_2806048_4	365046.Rta_19970	3.169e-12	68.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VHMA@28216|Betaproteobacteria,4A9UE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
PYH2_k127_2806048_1	420662.Mpe_A1783	4.387e-95	320.0	COG0625@1|root,COG0625@2|Bacteria,1P71B@1224|Proteobacteria,2VJ3I@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
PYH2_k127_2806048_0	864051.BurJ1DRAFT_2278	7.564e-131	436.0	COG4221@1|root,COG4221@2|Bacteria,1MVYG@1224|Proteobacteria,2WGHU@28216|Betaproteobacteria,1KJIZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH2_k127_2806048_2	864051.BurJ1DRAFT_4401	4.591e-62	223.0	COG5429@1|root,COG5429@2|Bacteria,1MW6R@1224|Proteobacteria,2VSC6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1223)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1223
PYH2_k127_2806048_3	1276756.AUEX01000042_gene2650	1.49e-13	76.0	COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,2VT83@28216|Betaproteobacteria,4AEKN@80864|Comamonadaceae	28216|Betaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
PYH2_k127_2810001_1	1408418.JNJH01000004_gene1993	6.197e-226	711.0	COG2252@1|root,COG2252@2|Bacteria,1QVW3@1224|Proteobacteria,2TWKP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PERMEase	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
PYH2_k127_2810001_0	1441930.Z042_06465	1.184e-244	758.0	COG0624@1|root,COG0624@2|Bacteria,1N20R@1224|Proteobacteria,1RYRN@1236|Gammaproteobacteria,3ZZTC@613|Serratia	1236|Gammaproteobacteria	E	Peptidase family M20/M25/M40	ygeY	-	-	ko:K05831	ko00220,ko00300,ko01100,ko01210,ko01230,map00220,map00300,map01100,map01210,map01230	M00031,M00763	R09779,R10933	RC00064,RC00090	ko00000,ko00001,ko00002	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_2810001_3	155864.EDL933_4071	1.944e-208	653.0	COG0078@1|root,COG0078@2|Bacteria,1N4DE@1224|Proteobacteria,1RSHV@1236|Gammaproteobacteria,3XPB7@561|Escherichia	1236|Gammaproteobacteria	F	carbamoyltransferase YgeW	ygeW	GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
PYH2_k127_2810001_2	502025.Hoch_2603	1.867e-212	681.0	COG0167@1|root,COG0479@1|root,COG0167@2|Bacteria,COG0479@2|Bacteria	2|Bacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	-	-	1.3.1.1,1.3.1.2,1.97.1.9	ko:K00207,ko:K12527,ko:K17723	ko00240,ko00410,ko00450,ko00770,ko00983,ko01100,map00240,map00410,map00450,map00770,map00983,map01100	M00046	R00977,R00978,R01414,R01415,R07229,R08226,R11026	RC00072,RC00123,RC02245,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	ATC_hydrolase,CCG,DHO_dh,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_20,Fer4_8,Pyr_redox_2
PYH2_k127_2810001_6	748247.AZKH_3407	7.404e-16	82.0	COG4876@1|root,COG4876@2|Bacteria,1NJCS@1224|Proteobacteria,2VYBB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2810001_4	196162.Noca_1628	6.779e-71	248.0	COG0498@1|root,COG0498@2|Bacteria,2IH7W@201174|Actinobacteria	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
PYH2_k127_2815132_0	1002340.AFCF01000033_gene3892	2.542e-139	450.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2TXS1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc
PYH2_k127_2815132_1	1002340.AFCF01000033_gene3891	9.514e-23	101.0	COG2198@1|root,COG2198@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K20976	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Hpt
PYH2_k127_2815132_2	402777.KB235898_gene5247	4.481e-16	78.0	COG0642@1|root,COG0784@1|root,COG3322@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3322@2|Bacteria,COG5002@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GAF,GAF_3,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg
PYH2_k127_2816081_2	329726.AM1_5749	2.013e-47	174.0	COG1089@1|root,COG1089@2|Bacteria,1G0M4@1117|Cyanobacteria	1117|Cyanobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
PYH2_k127_2816081_0	1265502.KB905932_gene1899	1.077e-172	547.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,4A9VQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
PYH2_k127_2816081_1	864051.BurJ1DRAFT_4440	1.748e-139	449.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria,1KJXV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
PYH2_k127_2816081_3	864051.BurJ1DRAFT_4441	2.128e-33	131.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,1KK5K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
PYH2_k127_2843305_11	29581.BW37_03523	3.356e-07	57.0	2AG1G@1|root,3165J@2|Bacteria,1PWX1@1224|Proteobacteria,2WCF8@28216|Betaproteobacteria,477GX@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2843305_6	402881.Plav_2019	1.828e-52	194.0	COG0625@1|root,COG0625@2|Bacteria,1RG4U@1224|Proteobacteria	1224|Proteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
PYH2_k127_2843305_8	267608.RSc0133	1.862e-30	122.0	COG4274@1|root,COG4274@2|Bacteria,1MZVV@1224|Proteobacteria,2VUPM@28216|Betaproteobacteria,1K8BT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM GYD family protein	-	-	-	-	-	-	-	-	-	-	-	-	GYD
PYH2_k127_2843305_5	1454004.AW11_00303	2.871e-63	230.0	COG2199@1|root,COG3706@2|Bacteria,1NC00@1224|Proteobacteria,2VQIK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
PYH2_k127_2843305_0	292415.Tbd_1269	1.525e-279	876.0	COG0745@1|root,COG5001@1|root,COG0745@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,EAL,GGDEF,PAS_4,Response_reg
PYH2_k127_2843305_10	261292.Nit79A3_3192	4.194e-27	120.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2WGU7@28216|Betaproteobacteria,373VB@32003|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM TonB-dependent receptor, beta-barrel	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH2_k127_2843305_3	987059.RBXJA2T_00600	2.877e-97	327.0	COG1684@1|root,COG1684@2|Bacteria,1NIF4@1224|Proteobacteria,2VQ64@28216|Betaproteobacteria,1KK7D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliR	-	-	ko:K02421	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_1
PYH2_k127_2843305_7	420662.Mpe_A0576	6.087e-35	137.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,2VU8S@28216|Betaproteobacteria,1KMB2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Role in flagellar biosynthesis	fliQ	-	-	ko:K02420	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_3
PYH2_k127_2843305_2	420662.Mpe_A0575	7.614e-114	374.0	COG1338@1|root,COG1338@2|Bacteria,1MVBU@1224|Proteobacteria,2VIU6@28216|Betaproteobacteria,1KJIU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Plays a role in the flagellum-specific transport system	fliP	-	-	ko:K02419	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliP
PYH2_k127_2843305_9	864051.BurJ1DRAFT_0267	1.248e-27	115.0	COG3190@1|root,COG3190@2|Bacteria,1NHJX@1224|Proteobacteria,2W9KI@28216|Betaproteobacteria,1KMGP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar biosynthesis protein, FliO	fliO	-	-	ko:K02418	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliO
PYH2_k127_2843305_4	987059.RBXJA2T_00620	2.44e-64	223.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2VSZ7@28216|Betaproteobacteria,1KKUP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar motor switch protein fliN	fliN	-	-	ko:K02417,ko:K03225	ko02030,ko02040,ko03070,map02030,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliMN_C
PYH2_k127_2843305_1	983917.RGE_16760	1.329e-169	535.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2VI0A@28216|Betaproteobacteria,1KK5A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar motor switch	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
PYH2_k127_2846091_2	395495.Lcho_0031	2.245e-11	74.0	COG0810@1|root,COG0810@2|Bacteria,1P1KD@1224|Proteobacteria	1224|Proteobacteria	C	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2846091_1	1097668.BYI23_B010120	3.438e-43	171.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2WESG@28216|Betaproteobacteria,1K748@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Ankyrin repeats (3 copies)	-	-	-	ko:K06867,ko:K21440	-	-	-	-	ko00000,ko04131	-	-	-	Ank_2,Ank_4,Ank_5
PYH2_k127_2846091_0	264198.Reut_B5419	3.023e-301	930.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2VMVP@28216|Betaproteobacteria,1KFG8@119060|Burkholderiaceae	28216|Betaproteobacteria	G	PQQ enzyme repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2,PQQ_3
PYH2_k127_2860243_0	864051.BurJ1DRAFT_1553	7.324e-299	930.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KJUI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
PYH2_k127_2860243_1	395495.Lcho_2531	6.334e-71	246.0	COG0558@1|root,COG0558@2|Bacteria,1RD5Y@1224|Proteobacteria,2VSGP@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
PYH2_k127_2860243_2	573.JG24_09270	1.381e-22	99.0	COG4136@1|root,COG4136@2|Bacteria,1RA88@1224|Proteobacteria,1S207@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ABC transporter	ynjD	-	-	ko:K05779	-	M00192	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
PYH2_k127_2865071_2	864051.BurJ1DRAFT_2259	3.547e-139	456.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria,2WI64@28216|Betaproteobacteria,1KJ0Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2865071_5	1265502.KB905940_gene3018	9.809e-91	300.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,4A9KP@80864|Comamonadaceae	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PYH2_k127_2865071_4	1223521.BBJX01000004_gene2442	1.032e-94	323.0	COG3971@1|root,COG3971@2|Bacteria,1R3UP@1224|Proteobacteria,2VNA2@28216|Betaproteobacteria,4ABDW@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2865071_6	1100720.ALKN01000043_gene2733	1.976e-24	110.0	COG2010@1|root,COG2010@2|Bacteria,1N71Z@1224|Proteobacteria,2VUHM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2865071_0	1286631.X805_33750	0.0	1031.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,1KKET@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
PYH2_k127_2865071_3	420662.Mpe_A1811	1.368e-115	381.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,1KK6I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
PYH2_k127_2865071_1	987059.RBXJA2T_08430	4.685e-160	510.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,1KK4D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
PYH2_k127_2865843_0	1380394.JADL01000009_gene3150	0.0	1049.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,2JREU@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
PYH2_k127_2865843_2	159087.Daro_0588	1.2e-29	121.0	2DU07@1|root,33NDR@2|Bacteria,1PUPQ@1224|Proteobacteria,2VY40@28216|Betaproteobacteria,2KXM2@206389|Rhodocyclales	206389|Rhodocyclales	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
PYH2_k127_2865843_1	522306.CAP2UW1_2419	3.5e-75	258.0	2DZXC@1|root,32VMF@2|Bacteria,1N29I@1224|Proteobacteria	1224|Proteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
PYH2_k127_2865843_3	1038922.PflQ2_2311	8.563e-21	94.0	COG0730@1|root,COG0730@2|Bacteria,1MVYH@1224|Proteobacteria,1RS3F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH2_k127_2881024_9	85643.Tmz1t_1956	0.0006343	43.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,2KUU4@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
PYH2_k127_2881024_5	983917.RGE_16160	1.489e-100	332.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,1KJ1F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
PYH2_k127_2881024_2	395495.Lcho_1055	6.824e-158	505.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,1KK3B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
PYH2_k127_2881024_4	338969.Rfer_2634	4.973e-121	395.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2VII6@28216|Betaproteobacteria,4ABCU@80864|Comamonadaceae	28216|Betaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, B subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH2_k127_2881024_3	420662.Mpe_A1456	3.295e-125	403.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2VHFT@28216|Betaproteobacteria,1KJX8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH2_k127_2881024_6	338969.Rfer_3968	4.73e-79	277.0	COG0095@1|root,COG0095@2|Bacteria,1RAZV@1224|Proteobacteria,2VQWN@28216|Betaproteobacteria,4ADV2@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	-
PYH2_k127_2881024_7	338969.Rfer_3967	2.377e-31	127.0	COG0508@1|root,COG0508@2|Bacteria,1NGVN@1224|Proteobacteria,2VYZ9@28216|Betaproteobacteria,4AG20@80864|Comamonadaceae	28216|Betaproteobacteria	C	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
PYH2_k127_2881024_1	338969.Rfer_3966	2.826e-203	635.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,4AD06@80864|Comamonadaceae	28216|Betaproteobacteria	C	Transketolase, C-terminal domain	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
PYH2_k127_2881024_0	338969.Rfer_3965	7.623e-205	639.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VN57@28216|Betaproteobacteria,4AJAZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	dehydrogenase, E1 component	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
PYH2_k127_2886248_1	318996.AXAZ01000008_gene4296	2.618e-20	91.0	COG2984@1|root,COG2984@2|Bacteria,1NPJJ@1224|Proteobacteria,2UUMS@28211|Alphaproteobacteria,3K4MG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
PYH2_k127_2886248_0	1123519.PSJM300_12395	9.031e-260	812.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,1RMIT@1236|Gammaproteobacteria,1Z0SR@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	M	Gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
PYH2_k127_2886477_3	402881.Plav_3039	7.21e-37	141.0	COG3748@1|root,COG3748@2|Bacteria,1RFIZ@1224|Proteobacteria,2U7B1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
PYH2_k127_2886477_0	426355.Mrad2831_5613	0.0	1122.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2TSZ9@28211|Alphaproteobacteria,1JRSQ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
PYH2_k127_2886477_2	1286631.X805_32600	7.664e-56	199.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,1KM2Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
PYH2_k127_2886477_1	987059.RBXJA2T_10359	2.108e-192	618.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VJSM@28216|Betaproteobacteria,1KJDU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ccoI	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
PYH2_k127_2889314_16	1156919.QWC_00410	0.0008741	42.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2VIBR@28216|Betaproteobacteria,3T3DW@506|Alcaligenaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_2889314_3	983917.RGE_03050	1.627e-178	565.0	COG1748@1|root,COG1748@2|Bacteria,1MY1G@1224|Proteobacteria,2VMNG@28216|Betaproteobacteria,1KN8J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
PYH2_k127_2889314_11	667632.KB890178_gene84	8.865e-58	204.0	COG1522@1|root,COG1522@2|Bacteria,1RE5H@1224|Proteobacteria,2VS27@28216|Betaproteobacteria,1K3TW@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_AsnC-type
PYH2_k127_2889314_6	1265502.KB905949_gene968	1.014e-158	512.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,4ABPQ@80864|Comamonadaceae	28216|Betaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
PYH2_k127_2889314_15	864051.BurJ1DRAFT_4415	5.12e-16	79.0	2EMEQ@1|root,33F3I@2|Bacteria,1NGX3@1224|Proteobacteria,2VY0E@28216|Betaproteobacteria,1KMUE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2889314_10	983917.RGE_10140	7.183e-69	255.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,1KKN3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
PYH2_k127_2889314_7	420662.Mpe_A0483	9.802e-130	423.0	COG4589@1|root,COG4589@2|Bacteria,1MX58@1224|Proteobacteria,2VH1P@28216|Betaproteobacteria,1KKB5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
PYH2_k127_2889314_8	1265502.KB905949_gene972	1.251e-102	339.0	COG0204@1|root,COG0204@2|Bacteria,1RA8V@1224|Proteobacteria,2VQ8G@28216|Betaproteobacteria,4ABCG@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
PYH2_k127_2889314_0	1265502.KB905949_gene973	2.211e-264	825.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,4AC6F@80864|Comamonadaceae	28216|Betaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
PYH2_k127_2889314_14	864051.BurJ1DRAFT_1200	3.237e-34	132.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,1KME0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KL	Belongs to the transcriptional regulatory Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
PYH2_k127_2889314_4	864051.BurJ1DRAFT_1201	2.658e-168	539.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,1KJF9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
PYH2_k127_2889314_9	420662.Mpe_A0487	2.015e-85	284.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria,1KKMY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SNARE associated Golgi protein	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
PYH2_k127_2889314_1	62928.azo3546	5.144e-225	719.0	COG2317@1|root,COG2317@2|Bacteria,1MW7T@1224|Proteobacteria,2VKEK@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	ctaQ	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
PYH2_k127_2889314_12	1287276.X752_07375	1.197e-55	200.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2TSR4@28211|Alphaproteobacteria,43JCE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2889314_5	987059.RBXJA2T_06860	1.107e-161	523.0	COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,2VMTI@28216|Betaproteobacteria,1KJHM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
PYH2_k127_2889314_13	420662.Mpe_A0490	2.694e-51	188.0	COG3937@1|root,COG3937@2|Bacteria,1RIXG@1224|Proteobacteria,2VT1J@28216|Betaproteobacteria,1KM36@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Poly(hydroxyalcanoate) granule associated protein (phasin)	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
PYH2_k127_2889314_2	864051.BurJ1DRAFT_1206	4.86e-220	690.0	COG1028@1|root,COG3320@1|root,COG1028@2|Bacteria,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,2VKRX@28216|Betaproteobacteria,1KMYT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
PYH2_k127_2903451_9	936455.KI421499_gene720	1.827e-10	63.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1
PYH2_k127_2903451_4	375286.mma_0692	8.102e-68	237.0	COG4574@1|root,COG4574@2|Bacteria,1MZEN@1224|Proteobacteria,2VUFF@28216|Betaproteobacteria,4773R@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Ecotin	eco	-	-	ko:K08276	-	-	-	-	ko00000	-	-	-	Ecotin
PYH2_k127_2903451_2	1454004.AW11_02641	2.525e-85	287.0	COG3449@1|root,COG3449@2|Bacteria,1RF2U@1224|Proteobacteria,2VST9@28216|Betaproteobacteria,1KR16@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	SOUL heme-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SOUL
PYH2_k127_2903451_7	1121921.KB898715_gene42	9.749e-31	123.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	spsF	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
PYH2_k127_2903451_8	323261.Noc_0445	1.285e-18	93.0	COG3905@1|root,COG3905@2|Bacteria,1NHN3@1224|Proteobacteria,1SGV1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
PYH2_k127_2903451_3	76114.ebA2022	1.217e-69	245.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2VQIR@28216|Betaproteobacteria,2KW28@206389|Rhodocyclales	206389|Rhodocyclales	L	NADH pyrophosphatase-like rudimentary NUDIX domain	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
PYH2_k127_2903451_1	296591.Bpro_2055	6.022e-148	479.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,4A9S4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
PYH2_k127_2903451_5	1380394.JADL01000001_gene2255	1.066e-66	239.0	COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,2TRC6@28211|Alphaproteobacteria,2JT16@204441|Rhodospirillales	204441|Rhodospirillales	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PYH2_k127_2903451_0	279714.FuraDRAFT_2329	7.337e-272	850.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VHAT@28216|Betaproteobacteria,2KTS6@206351|Neisseriales	206351|Neisseriales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_2903451_6	365046.Rta_19980	1.088e-52	189.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,2VSCY@28216|Betaproteobacteria,4AEWX@80864|Comamonadaceae	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
PYH2_k127_2912526_6	420662.Mpe_A1964	2.191e-74	256.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,1KJ1U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
PYH2_k127_2912526_4	987059.RBXJA2T_00445	5.453e-102	338.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria,1KJ5K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
PYH2_k127_2912526_2	420662.Mpe_A1961	1.132e-132	435.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,1KJGZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
PYH2_k127_2912526_0	864051.BurJ1DRAFT_2309	2.55e-300	936.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,1KJ4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
PYH2_k127_2912526_8	420662.Mpe_A1959	7.083e-45	171.0	COG0810@1|root,COG0810@2|Bacteria,1N46T@1224|Proteobacteria,2VV7R@28216|Betaproteobacteria,1KM9I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	-
PYH2_k127_2912526_7	1208919.CDSE_0414	4.262e-57	205.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,1KPZ4@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
PYH2_k127_2912526_3	864051.BurJ1DRAFT_2312	5.721e-111	368.0	COG0697@1|root,COG0697@2|Bacteria,1MXCD@1224|Proteobacteria,2VMQB@28216|Betaproteobacteria,1KJ73@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_2912526_9	395495.Lcho_1929	3.885e-41	154.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,1KM9J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hupB	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PYH2_k127_2912526_1	420662.Mpe_A1955	2.748e-228	724.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,1KJR8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	peptidylprolyl isomerase	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
PYH2_k127_2912526_5	864051.BurJ1DRAFT_2317	6.977e-100	332.0	COG4974@1|root,COG4974@2|Bacteria,1QZ7D@1224|Proteobacteria,2WHS3@28216|Betaproteobacteria,1KNGB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Arm-DNA-bind_2,Phage_integrase
PYH2_k127_2924258_3	296591.Bpro_3401	2.725e-92	309.0	COG0477@1|root,COG2814@2|Bacteria,1MX2P@1224|Proteobacteria,2VIIJ@28216|Betaproteobacteria,4A9MC@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_2924258_2	338969.Rfer_0649	1.195e-118	390.0	COG0697@1|root,COG0697@2|Bacteria,1MX07@1224|Proteobacteria,2VN9W@28216|Betaproteobacteria,4ACVN@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_2924258_0	748247.AZKH_3155	6.9e-272	848.0	COG0028@1|root,COG0028@2|Bacteria,1MWUB@1224|Proteobacteria,2VMC1@28216|Betaproteobacteria,2KY78@206389|Rhodocyclales	206389|Rhodocyclales	EH	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.3.3.15	ko:K03852	ko00430,map00430	-	R05651	RC02903,RC02909	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_2924258_1	1504672.669787430	2.685e-148	485.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VJBE@28216|Betaproteobacteria,4ACD2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_2934647_2	1504672.669784576	2.104e-39	166.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2VQ3M@28216|Betaproteobacteria,4ADGV@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
PYH2_k127_2934647_0	1504672.669784577	6.532e-242	765.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VMVH@28216|Betaproteobacteria,4ABFS@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD2	-	1.1.1.308	ko:K15509	-	-	-	-	ko00000,ko01000	-	-	-	Histidinol_dh
PYH2_k127_2934647_1	1504672.669784578	5.458e-106	347.0	COG0715@1|root,COG0715@2|Bacteria,1NUUC@1224|Proteobacteria,2VJ53@28216|Betaproteobacteria,4ABAQ@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
PYH2_k127_2962730_3	864051.BurJ1DRAFT_4863	1.2e-122	400.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VI76@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems ATPase component	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_2962730_4	864051.BurJ1DRAFT_4862	7.074e-115	389.0	COG0410@1|root,COG0410@2|Bacteria,1MW9R@1224|Proteobacteria,2VNG7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	abc transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_2962730_1	864051.BurJ1DRAFT_4861	9.46e-157	514.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,1KIW4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_2962730_0	864051.BurJ1DRAFT_4860	1.482e-176	561.0	COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,2VJA3@28216|Betaproteobacteria,1KJ4J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_2962730_2	864051.BurJ1DRAFT_4858	1.563e-137	458.0	COG2267@1|root,COG2267@2|Bacteria,1NTH9@1224|Proteobacteria,2WGMM@28216|Betaproteobacteria,1KPDQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
PYH2_k127_2971721_4	983917.RGE_33340	2.08e-63	219.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,1KITX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	DM	peptidase	nlpD	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
PYH2_k127_2971721_1	420662.Mpe_A1255	1.139e-140	456.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,1KK1Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	RNA polymerase sigma	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
PYH2_k127_2971721_2	365046.Rta_24390	6.32e-122	398.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,4AGY1@80864|Comamonadaceae	28216|Betaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
PYH2_k127_2971721_0	987059.RBXJA2T_09642	2.383e-198	626.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,1KJT2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
PYH2_k127_2971721_3	395495.Lcho_2825	2.43e-88	294.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,1KJ3S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the BI1 family	yccA	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
PYH2_k127_2972683_1	365046.Rta_11770	1.224e-51	188.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria,4AD7H@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1
PYH2_k127_2972683_2	395495.Lcho_4291	2.29e-44	164.0	COG3671@1|root,COG3671@2|Bacteria,1N51H@1224|Proteobacteria,2VUKZ@28216|Betaproteobacteria,1KMEZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2972683_0	420662.Mpe_A2088	1.037e-203	639.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KJN7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
PYH2_k127_2973336_6	864051.BurJ1DRAFT_3344	2.646e-20	93.0	2DRY7@1|root,33DN9@2|Bacteria,1NJPX@1224|Proteobacteria,2VYHU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2973336_4	864051.BurJ1DRAFT_3343	1.077e-43	175.0	COG1974@1|root,COG1974@2|Bacteria,1QUQ8@1224|Proteobacteria,2VWS0@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
PYH2_k127_2973336_0	864051.BurJ1DRAFT_3342	1.475e-239	752.0	COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2VPWB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2
PYH2_k127_2973336_1	580332.Slit_1692	1.026e-101	342.0	COG2175@1|root,COG2175@2|Bacteria,1R5KS@1224|Proteobacteria,2VIG6@28216|Betaproteobacteria,44W7U@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
PYH2_k127_2973336_2	864051.BurJ1DRAFT_3340	1.579e-74	255.0	28IET@1|root,2Z8GT@2|Bacteria,1R4FQ@1224|Proteobacteria,2VUGA@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2973336_3	864051.BurJ1DRAFT_3339	1.953e-54	192.0	COG2920@1|root,COG2920@2|Bacteria,1N2HP@1224|Proteobacteria,2VVGF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
PYH2_k127_2973336_5	864051.BurJ1DRAFT_3338	1.179e-36	140.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,2VVIY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cas6 Crispr	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
PYH2_k127_2980326_2	1265502.KB905955_gene463	5.327e-67	253.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,2VQ4Q@28216|Betaproteobacteria,4ADGD@80864|Comamonadaceae	28216|Betaproteobacteria	I	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH2_k127_2980326_0	983917.RGE_35160	5.673e-178	575.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2VH2B@28216|Betaproteobacteria,1KJU2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	MatE	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
PYH2_k127_2980326_1	395495.Lcho_0737	1.242e-71	245.0	COG3313@1|root,COG3313@2|Bacteria,1N711@1224|Proteobacteria,2VW2B@28216|Betaproteobacteria,1KKUM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3717)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289,DUF3717
PYH2_k127_2980326_3	83332.Rv0577	3.23e-41	166.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,23F0E@1762|Mycobacteriaceae	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
PYH2_k127_2980326_4	338969.Rfer_2478	9.116e-18	85.0	COG0028@1|root,COG0028@2|Bacteria,1MXDW@1224|Proteobacteria,2VI39@28216|Betaproteobacteria	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_2980429_18	420662.Mpe_A2923	5.419e-09	57.0	COG1846@1|root,COG1846@2|Bacteria,1N7G0@1224|Proteobacteria,2VT0A@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
PYH2_k127_2980429_16	1268622.AVS7_01806	1.779e-18	87.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,4ABJD@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_2980429_14	392499.Swit_2665	8.937e-43	163.0	COG3791@1|root,COG3791@2|Bacteria,1RE8S@1224|Proteobacteria,2U73V@28211|Alphaproteobacteria,2K4NT@204457|Sphingomonadales	204457|Sphingomonadales	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
PYH2_k127_2980429_11	864051.BurJ1DRAFT_1589	1.086e-79	270.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,2VQ6X@28216|Betaproteobacteria,1KKDE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
PYH2_k127_2980429_5	84531.JMTZ01000044_gene993	2.509e-111	372.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,1RR31@1236|Gammaproteobacteria,1X47R@135614|Xanthomonadales	135614|Xanthomonadales	S	Zn-dependent hydrolases including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH2_k127_2980429_7	204773.HEAR0891	9.814e-110	363.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VKAX@28216|Betaproteobacteria,4746R@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Chromate resistance exported protein	chrB	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
PYH2_k127_2980429_0	395495.Lcho_0450	3.564e-244	759.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,1KJAV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
PYH2_k127_2980429_3	543728.Vapar_5758	3.775e-156	497.0	COG0605@1|root,COG0607@1|root,COG0605@2|Bacteria,COG0607@2|Bacteria,1R4Z3@1224|Proteobacteria,2VN2K@28216|Betaproteobacteria,4ADCX@80864|Comamonadaceae	28216|Betaproteobacteria	P	Superoxide dismutase	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Rhodanese,Sod_Fe_C
PYH2_k127_2980429_13	1042209.HK44_005190	2.043e-67	243.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,1RUTW@1236|Gammaproteobacteria,1YS6D@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
PYH2_k127_2980429_2	1392838.AWNM01000070_gene1192	8.716e-163	526.0	COG0477@1|root,COG2814@2|Bacteria,1QW9T@1224|Proteobacteria,2W1Q9@28216|Betaproteobacteria,3T5SY@506|Alcaligenaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_2980429_20	35754.JNYJ01000008_gene3314	6.704e-07	57.0	COG4319@1|root,COG4319@2|Bacteria,2IRHC@201174|Actinobacteria,4DFA7@85008|Micromonosporales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
PYH2_k127_2980429_10	1380391.JIAS01000008_gene5579	3.622e-87	293.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TTGT@28211|Alphaproteobacteria,2JSAA@204441|Rhodospirillales	204441|Rhodospirillales	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
PYH2_k127_2980429_17	1380394.JADL01000010_gene4160	6.382e-12	78.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,2JZPA@204441|Rhodospirillales	204441|Rhodospirillales	E	Cobalamin-independent synthase, Catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
PYH2_k127_2980429_12	595537.Varpa_3816	1.755e-70	243.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2VKQS@28216|Betaproteobacteria,4AC8E@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM NADPH-dependent FMN reductase	-	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
PYH2_k127_2980429_21	381666.H16_A1238	7.445e-07	57.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_2980429_1	595537.Varpa_5341	4.1e-179	583.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VPYV@28216|Betaproteobacteria,4ACSI@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH2_k127_2980429_6	94624.Bpet2878	2.094e-110	367.0	COG0372@1|root,COG0372@2|Bacteria,1MUII@1224|Proteobacteria,2VQIG@28216|Betaproteobacteria,3T5BR@506|Alcaligenaceae	28216|Betaproteobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PYH2_k127_2980429_4	543728.Vapar_5652	1.7e-114	377.0	COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,2VM31@28216|Betaproteobacteria,4AFA6@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.1,1.13.11.37	ko:K03381,ko:K04098,ko:K15253	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R03891,R04061,R04258,R05299,R05407,R05409,R06833,R06839,R08114,R08115,R09134	RC00388,RC00535,RC01016,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
PYH2_k127_2980429_19	595537.Varpa_0340	6.736e-08	56.0	COG4627@1|root,COG4627@2|Bacteria,1N8RI@1224|Proteobacteria,2VUSF@28216|Betaproteobacteria,4AEY5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Stress responsive alpha-beta barrel	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
PYH2_k127_2980429_15	264198.Reut_B4138	9.14e-35	136.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	yciI	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K05527,ko:K09780	-	-	-	-	ko00000,ko03000	-	-	-	YCII
PYH2_k127_2980429_9	1231391.AMZF01000020_gene2011	1.983e-91	306.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria	1224|Proteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_2980429_8	1231391.AMZF01000020_gene2010	4.102e-95	318.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUFT@1224|Proteobacteria	1224|Proteobacteria	E	(ABC) transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_2990173_3	1538295.JY96_13760	1.671e-46	186.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,2VR0I@28216|Betaproteobacteria,1KPBU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2990173_1	1265502.KB905972_gene1341	5.655e-91	308.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2VR7D@28216|Betaproteobacteria,4AJE8@80864|Comamonadaceae	28216|Betaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2990173_2	864051.BurJ1DRAFT_1347	4.606e-78	277.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,2VR0I@28216|Betaproteobacteria,1KPBU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_2990173_0	987059.RBXJA2T_17534	1.65e-180	571.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VJNS@28216|Betaproteobacteria,1KJXY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904	2.7.7.7	ko:K02346,ko:K03502	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
PYH2_k127_2992413_0	983917.RGE_27490	1.607e-182	577.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,1KJG9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
PYH2_k127_2992413_1	983917.RGE_27480	1.751e-139	448.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,1KJ28@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
PYH2_k127_2992413_3	864051.BurJ1DRAFT_2947	5.086e-18	87.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,1KMRR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
PYH2_k127_2992413_2	983917.RGE_27460	3.226e-95	315.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,1KKAN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
PYH2_k127_3003563_8	1121271.AUCM01000020_gene2828	4.61e-56	213.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2TQQ7@28211|Alphaproteobacteria	1224|Proteobacteria	I	Belongs to the thiolase family	bktB	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K07508	ko00062,ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00062,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00085,M00087,M00088,M00095,M00373,M00374,M00375	R00238,R00391,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747	RC00004,RC00326,RC00405,RC01702	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_3003563_6	358220.C380_00350	1.98e-105	361.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VKPR@28216|Betaproteobacteria,4AA4P@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_3003563_7	1125863.JAFN01000001_gene396	2.06e-69	259.0	COG0559@1|root,COG0559@2|Bacteria,1N54M@1224|Proteobacteria,42PNV@68525|delta/epsilon subdivisions,2WJVJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3003563_3	1121033.AUCF01000012_gene869	1.139e-125	411.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TT26@28211|Alphaproteobacteria,2JPYZ@204441|Rhodospirillales	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH2_k127_3003563_4	1211115.ALIQ01000216_gene2452	1.136e-116	388.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2TQZC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_3003563_5	1268622.AVS7_01010	8.715e-106	351.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VINW@28216|Betaproteobacteria,4ACAN@80864|Comamonadaceae	28216|Betaproteobacteria	E	ABC transporter	livF_15	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_3003563_0	1121033.AUCF01000012_gene872	1.119e-214	696.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2TSSI@28211|Alphaproteobacteria,2JPQ1@204441|Rhodospirillales	204441|Rhodospirillales	I	COG1022 Long-chain acyl-CoA synthetases (AMP-forming)	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PYH2_k127_3003563_2	1205680.CAKO01000014_gene116	2.004e-144	467.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2TR15@28211|Alphaproteobacteria,2JV29@204441|Rhodospirillales	204441|Rhodospirillales	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_3003563_1	1265502.KB905932_gene1783	4.548e-213	673.0	COG1178@1|root,COG1178@2|Bacteria,1MWEV@1224|Proteobacteria,2VI20@28216|Betaproteobacteria,4AC7K@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	fbpB	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
PYH2_k127_3003563_9	864051.BurJ1DRAFT_1398	7.554e-51	189.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VHGM@28216|Betaproteobacteria,1KJ77@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
PYH2_k127_3020945_7	1283300.ATXB01000001_gene392	1.457e-11	64.0	28HMZ@1|root,2Z7WD@2|Bacteria,1MU3Q@1224|Proteobacteria,1RRUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3604)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
PYH2_k127_3020945_3	1217718.ALOU01000007_gene1258	6.748e-64	231.0	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2W0N2@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
PYH2_k127_3020945_1	395492.Rleg2_5109	3.283e-96	338.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,4BA0J@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
PYH2_k127_3020945_2	395492.Rleg2_5110	4.229e-64	238.0	COG2370@1|root,COG2370@2|Bacteria,1N08F@1224|Proteobacteria,2UA0Y@28211|Alphaproteobacteria,4B7VB@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	hupE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03192	-	-	-	-	ko00000	-	-	-	HupE_UreJ
PYH2_k127_3020945_4	395492.Rleg2_5111	4.502e-32	141.0	COG2370@1|root,COG2370@2|Bacteria,1PPXD@1224|Proteobacteria,2V2C6@28211|Alphaproteobacteria,4BI58@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ
PYH2_k127_3020945_5	1500897.JQNA01000002_gene701	9.268e-18	94.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,1K30A@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
PYH2_k127_3020945_0	296591.Bpro_1403	3.951e-154	494.0	COG1234@1|root,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,2VNMY@28216|Betaproteobacteria,4AGEE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
PYH2_k127_3020945_6	1267005.KB911259_gene3953	1.93e-13	72.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	1.8.4.14	ko:K08968	ko00270,map00270	-	R02025	RC00639	ko00000,ko00001,ko01000	-	-	-	GAF_2
PYH2_k127_3031329_4	987059.RBXJA2T_12757	4.457e-196	618.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,1KJIS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
PYH2_k127_3031329_8	420662.Mpe_A1419	1.135e-51	186.0	COG5319@1|root,COG5319@2|Bacteria,1MZN2@1224|Proteobacteria,2VSCN@28216|Betaproteobacteria,1KM7X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1178
PYH2_k127_3031329_7	420662.Mpe_A1418	1.961e-74	255.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,1KKQA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
PYH2_k127_3031329_2	420662.Mpe_A1416	8.995e-229	717.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,1KJ1X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
PYH2_k127_3031329_1	420662.Mpe_A1415	1.416e-270	837.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,1KK0V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
PYH2_k127_3031329_0	1265502.KB905936_gene2653	0.0	1057.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,4A9X6@80864|Comamonadaceae	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
PYH2_k127_3031329_9	987059.RBXJA2T_12727	1.926e-43	176.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,1KM2T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
PYH2_k127_3031329_6	864051.BurJ1DRAFT_3600	1.76e-78	267.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,1KKDT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
PYH2_k127_3031329_5	1504672.669786547	2.985e-94	311.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,4A9UU@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
PYH2_k127_3031329_3	1265502.KB905936_gene2657	6.372e-197	617.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,4A9M0@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
PYH2_k127_3031329_10	987059.RBXJA2T_12707	6.335e-12	66.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,1KJ4S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADH-quinone oxidoreductase	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
PYH2_k127_3039278_2	614083.AWQR01000001_gene3119	3.852e-43	158.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VNQX@28216|Betaproteobacteria,4AC0P@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3039278_0	358220.C380_03400	3.644e-183	577.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VKYI@28216|Betaproteobacteria,4A9Y9@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3039278_1	1157708.KB907464_gene474	2.809e-72	247.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJRS@28216|Betaproteobacteria,4AAWC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_3039444_2	1040989.AWZU01000127_gene1264	0.0003166	44.0	COG3903@1|root,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,2TQQR@28211|Alphaproteobacteria,3JTWJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PYH2_k127_3039444_0	580332.Slit_1738	1.168e-36	148.0	COG0767@1|root,COG0767@2|Bacteria,1N2HV@1224|Proteobacteria	1224|Proteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
PYH2_k127_3039444_1	1219031.BBJR01000025_gene91	3.845e-05	55.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria,2VK63@28216|Betaproteobacteria,4AA5X@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
PYH2_k127_3042296_2	987059.RBXJA2T_09697	3.526e-29	117.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,1KJ1R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PYH2_k127_3042296_1	1439940.BAY1663_04986	1.235e-51	190.0	COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,1S2AY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	phosphohistidine phosphatase, SixA	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,His_Phos_1
PYH2_k127_3042296_0	365046.Rta_23550	3.635e-63	222.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,4AC4P@80864|Comamonadaceae	28216|Betaproteobacteria	FP	PFAM Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
PYH2_k127_3046620_2	595537.Varpa_5618	1.39e-127	413.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJRS@28216|Betaproteobacteria,4AAWC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_3046620_1	1123504.JQKD01000002_gene3679	5.392e-139	446.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNC@28216|Betaproteobacteria,4ABEP@80864|Comamonadaceae	28216|Betaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_3046620_0	1123504.JQKD01000002_gene3680	1.164e-218	687.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,4A9UR@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PYH2_k127_3049488_4	66377.JOBH01000001_gene1160	1.225e-25	113.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
PYH2_k127_3049488_1	420662.Mpe_A0974	3.245e-138	443.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VN7W@28216|Betaproteobacteria,1KIZJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the HpcH HpaI aldolase family	-	-	4.1.2.52	ko:K02510	ko00350,ko01120,map00350,map01120	-	R01645,R01647	RC00307,RC00572,RC00574,RC03057	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
PYH2_k127_3049488_2	365044.Pnap_3770	8.244e-62	216.0	COG1522@1|root,COG1522@2|Bacteria,1MZ9D@1224|Proteobacteria,2VR5I@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
PYH2_k127_3049488_0	358220.C380_02505	1.51e-149	485.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,2VHIM@28216|Betaproteobacteria,4ABP6@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Ornithine cyclodeaminase mu-crystallin	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
PYH2_k127_3049488_5	1109445.AGSX01000004_gene676	2.999e-08	59.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,1RN48@1236|Gammaproteobacteria,1Z09P@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	CE	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	GO:0000166,GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0003842,GO:0004657,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006355,GO:0006520,GO:0006536,GO:0006560,GO:0006562,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009889,GO:0009890,GO:0009892,GO:0009898,GO:0009987,GO:0010133,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043565,GO:0043648,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0048519,GO:0048523,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0098552,GO:0098562,GO:0140110,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iPC815.YPO1851,iSbBS512_1146.SbBS512_E2304	Aldedh,Pro_dh,Pro_dh-DNA_bdg
PYH2_k127_3054853_16	760117.JN27_04890	0.0007427	42.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VM2H@28216|Betaproteobacteria,476H0@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	UvrD-like helicase C-terminal domain	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PYH2_k127_3054853_2	365046.Rta_04250	9.163e-223	700.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,4ACB3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH2_k127_3054853_13	365046.Rta_04240	1.045e-56	202.0	COG3090@1|root,COG3090@2|Bacteria,1NDFB@1224|Proteobacteria,2W4QP@28216|Betaproteobacteria,4AIFI@80864|Comamonadaceae	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH2_k127_3054853_6	365046.Rta_04230	7.791e-167	530.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VHPP@28216|Betaproteobacteria,4ABME@80864|Comamonadaceae	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH2_k127_3054853_12	864051.BurJ1DRAFT_4434	1.016e-58	208.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2VJXA@28216|Betaproteobacteria,1KK4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
PYH2_k127_3054853_15	1158292.JPOE01000005_gene179	3.657e-29	118.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria,2VJXA@28216|Betaproteobacteria,1KK4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
PYH2_k127_3054853_11	864051.BurJ1DRAFT_3927	1.568e-110	391.0	COG1024@1|root,COG1024@2|Bacteria,1MWYZ@1224|Proteobacteria,2VJYU@28216|Betaproteobacteria,1KIY0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.155	ko:K20036	ko00920,map00920	-	R10936	RC00004,RC03306,RC03307	ko00000,ko00001,ko01000	-	-	-	ECH_1
PYH2_k127_3054853_1	395495.Lcho_0993	3.696e-271	862.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2VIB6@28216|Betaproteobacteria,1KJUM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme	fcs	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
PYH2_k127_3054853_8	864051.BurJ1DRAFT_3925	1.943e-124	402.0	COG1028@1|root,COG1028@2|Bacteria,1MUBQ@1224|Proteobacteria,2VIYH@28216|Betaproteobacteria,1KJXA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
PYH2_k127_3054853_5	365044.Pnap_0800	3.389e-172	548.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2VHP9@28216|Betaproteobacteria,4ACT4@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_3054853_7	395495.Lcho_0990	2.108e-162	518.0	COG0559@1|root,COG0559@2|Bacteria,1MXMC@1224|Proteobacteria,2VJ1Y@28216|Betaproteobacteria,1KKBR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3054853_0	864051.BurJ1DRAFT_3922	3.43e-287	893.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,1KKAU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH2_k127_3054853_10	395495.Lcho_0988	3.183e-112	367.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNG@28216|Betaproteobacteria,1KJM2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_3054853_14	864051.BurJ1DRAFT_3919	6.414e-33	143.0	COG1846@1|root,COG1846@2|Bacteria,1RFUJ@1224|Proteobacteria,2VURD@28216|Betaproteobacteria,1KMAX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
PYH2_k127_3054853_3	1158292.JPOE01000005_gene1327	1.26e-205	646.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,2VH77@28216|Betaproteobacteria,1KJW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain	lldD	-	1.1.2.3,1.1.3.15	ko:K00101,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00196,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FMN_dh
PYH2_k127_3054853_4	94624.Bpet3940	5.631e-178	571.0	COG0246@1|root,COG0246@2|Bacteria,1MVZ7@1224|Proteobacteria,2VIIB@28216|Betaproteobacteria,3T6ZS@506|Alcaligenaceae	28216|Betaproteobacteria	G	COG0246 Mannitol-1-phosphate altronate dehydrogenases	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
PYH2_k127_3054853_9	543728.Vapar_2883	3.155e-123	395.0	COG4948@1|root,COG4948@2|Bacteria,1MURK@1224|Proteobacteria,2VJR9@28216|Betaproteobacteria,4A9VX@80864|Comamonadaceae	28216|Betaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	rspA	-	4.2.1.8	ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
PYH2_k127_3062463_2	314270.RB2083_3680	2.63e-09	61.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3ZG4T@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_3062463_0	411684.HPDFL43_14512	2.36e-181	575.0	COG4948@1|root,COG4948@2|Bacteria,1R63G@1224|Proteobacteria,2TT3A@28211|Alphaproteobacteria,43GT2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
PYH2_k127_3062463_1	384765.SIAM614_28352	3.078e-156	505.0	COG1167@1|root,COG1167@2|Bacteria,1MVGT@1224|Proteobacteria,2TRK7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
PYH2_k127_3068413_4	420662.Mpe_A2570	3.254e-57	200.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,1KKMC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
PYH2_k127_3068413_1	420662.Mpe_A2571	4.495e-187	591.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,1KJ4Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
PYH2_k127_3068413_2	864051.BurJ1DRAFT_2844	8.78e-167	533.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,2VKGI@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PYH2_k127_3068413_7	864051.BurJ1DRAFT_2092	0.0004857	43.0	COG2938@1|root,COG2938@2|Bacteria,1N2AS@1224|Proteobacteria,2VVYR@28216|Betaproteobacteria,1KMEM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
PYH2_k127_3068413_5	1265502.KB905931_gene1767	5.928e-39	153.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2VWK8@28216|Betaproteobacteria,4AF4Q@80864|Comamonadaceae	28216|Betaproteobacteria	O	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
PYH2_k127_3068413_3	1095769.CAHF01000010_gene1137	4.223e-121	398.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2VJHK@28216|Betaproteobacteria,473AH@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
PYH2_k127_3068413_0	1265502.KB905931_gene1765	1.093e-238	743.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,2VHFR@28216|Betaproteobacteria,4AAGK@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM cytochrome bd ubiquinol oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
PYH2_k127_3068413_6	1000565.METUNv1_00748	1.593e-09	59.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2VHSQ@28216|Betaproteobacteria,2KVCB@206389|Rhodocyclales	206389|Rhodocyclales	C	oxidase, subunit	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
PYH2_k127_3072799_0	1265502.KB905931_gene1764	4.914e-155	495.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,2VHSQ@28216|Betaproteobacteria,4AD1I@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
PYH2_k127_3072799_1	864051.BurJ1DRAFT_2843	2.627e-72	252.0	COG3012@1|root,COG3318@1|root,COG3012@2|Bacteria,COG3318@2|Bacteria,1R4KR@1224|Proteobacteria,2VHV9@28216|Betaproteobacteria,1KNJ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0149)	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
PYH2_k127_3093087_8	420662.Mpe_A1207	3.013e-26	109.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2VH8U@28216|Betaproteobacteria,1KJJ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
PYH2_k127_3093087_4	887062.HGR_07451	1.243e-115	380.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,4AAK0@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
PYH2_k127_3093087_6	987059.RBXJA2T_17509	5.83e-65	226.0	COG4539@1|root,COG4539@2|Bacteria,1RHUB@1224|Proteobacteria,2VTDF@28216|Betaproteobacteria,1KM7Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF962)	-	-	-	-	-	-	-	-	-	-	-	-	DUF962
PYH2_k127_3093087_3	420662.Mpe_A1176	3.686e-131	428.0	COG1526@1|root,COG1526@2|Bacteria,1MY28@1224|Proteobacteria,2VK94@28216|Betaproteobacteria,1KJG6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
PYH2_k127_3093087_9	864051.BurJ1DRAFT_1327	9.639e-24	110.0	2CKKR@1|root,332MC@2|Bacteria,1NCAT@1224|Proteobacteria,2VW6M@28216|Betaproteobacteria,1KMMV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3093087_1	395495.Lcho_3725	3.348e-155	502.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,1KJRA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Formate dehydrogenase gamma subunit	fdhC	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
PYH2_k127_3093087_10	795666.MW7_2452	1.784e-14	79.0	2EIHA@1|root,33C8N@2|Bacteria,1NG9G@1224|Proteobacteria,2VXQQ@28216|Betaproteobacteria,1K9I4@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3093087_2	420662.Mpe_A1171	1.064e-132	423.0	COG0437@1|root,COG0437@2|Bacteria,1MU5T@1224|Proteobacteria,2VJXP@28216|Betaproteobacteria,1KKF1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	fdhB	-	-	ko:K00124,ko:K07307	ko00630,ko00680,ko00920,ko01100,ko01120,ko01200,map00630,map00680,map00920,map01100,map01120,map01200	-	R00519,R09501	RC02555,RC02796	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_7
PYH2_k127_3093087_0	420662.Mpe_A1170	0.0	1833.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,1KK82@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	fdhA	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
PYH2_k127_3093087_11	365046.Rta_30520	4.698e-14	74.0	2ENGM@1|root,33G44@2|Bacteria,1NIB7@1224|Proteobacteria,2VYFS@28216|Betaproteobacteria,4AG1A@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3093087_5	864051.BurJ1DRAFT_1332	3.554e-88	297.0	COG3381@1|root,COG3381@2|Bacteria,1MWWM@1224|Proteobacteria,2VJ39@28216|Betaproteobacteria,1KKHR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Nitrate reductase delta subunit	torD	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_del
PYH2_k127_3093087_7	864051.BurJ1DRAFT_1331	1.02e-57	201.0	COG1148@1|root,COG1148@2|Bacteria,1QUQG@1224|Proteobacteria,2VMBE@28216|Betaproteobacteria,1KJCC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
PYH2_k127_3122572_3	1121033.AUCF01000004_gene5013	1.336e-21	100.0	COG3603@1|root,COG3603@2|Bacteria,1RI6G@1224|Proteobacteria,2UFGZ@28211|Alphaproteobacteria,2JZPN@204441|Rhodospirillales	204441|Rhodospirillales	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT_7
PYH2_k127_3122572_1	1157708.KB907462_gene930	1.261e-74	260.0	COG0589@1|root,COG0589@2|Bacteria,1QD8E@1224|Proteobacteria,2VTUB@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_3122572_0	420662.Mpe_A2143	2.124e-97	334.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,1KJF2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_3122572_2	420662.Mpe_A2142	4.147e-49	183.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VIAK@28216|Betaproteobacteria,1KMB3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
PYH2_k127_3122572_4	864051.BurJ1DRAFT_2517	2.897e-20	91.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,1QTXM@1224|Proteobacteria,2VIWW@28216|Betaproteobacteria,1KJXN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	AlkA N-terminal domain	ada	-	3.2.2.21	ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
PYH2_k127_3126278_3	1037409.BJ6T_87360	3.107e-31	128.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_3126278_0	748247.AZKH_4049	3.411e-218	686.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria,2KUH1@206389|Rhodocyclales	206389|Rhodocyclales	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3126278_1	748247.AZKH_4048	3.559e-159	528.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,2VHKN@28216|Betaproteobacteria,2KVG9@206389|Rhodocyclales	206389|Rhodocyclales	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
PYH2_k127_3126278_2	748247.AZKH_4047	1.156e-69	247.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,2KY4A@206389|Rhodocyclales	206389|Rhodocyclales	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
PYH2_k127_3140165_0	543728.Vapar_1557	1.533e-152	489.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2VJ0J@28216|Betaproteobacteria,4AD4F@80864|Comamonadaceae	28216|Betaproteobacteria	E	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
PYH2_k127_3140165_1	1100720.ALKN01000037_gene1900	2.501e-145	464.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VKAQ@28216|Betaproteobacteria,4ABTJ@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH2_k127_3154023_0	420662.Mpe_A1387	1.487e-143	458.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,2VH5Q@28216|Betaproteobacteria,1KIZ8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH2_k127_3154023_1	1265502.KB905936_gene2677	5.44e-140	462.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,4AAHS@80864|Comamonadaceae	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
PYH2_k127_3154023_2	420662.Mpe_A2256	3.626e-105	345.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,1KK0B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
PYH2_k127_3154023_3	269799.Gmet_0053	4.571e-66	245.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria,43TZR@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PYH2_k127_3154023_4	580332.Slit_2591	9.884e-25	112.0	COG0457@1|root,COG0457@2|Bacteria,1N260@1224|Proteobacteria,2VTG6@28216|Betaproteobacteria,44VWA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	ko:K12284	-	-	-	-	ko00000,ko02044	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
PYH2_k127_3162381_8	1217718.ALOU01000010_gene953	3.259e-75	261.0	COG0702@1|root,COG0702@2|Bacteria,1PDQP@1224|Proteobacteria,2W175@28216|Betaproteobacteria,1K5AY@119060|Burkholderiaceae	28216|Betaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
PYH2_k127_3162381_7	580332.Slit_1984	5.597e-78	266.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
PYH2_k127_3162381_6	279714.FuraDRAFT_1503	5.062e-81	281.0	COG0583@1|root,COG0583@2|Bacteria,1MVD8@1224|Proteobacteria,2VP85@28216|Betaproteobacteria	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_3162381_2	395495.Lcho_1193	3.132e-231	720.0	COG1960@1|root,COG1960@2|Bacteria,1MUK0@1224|Proteobacteria,2VHDV@28216|Betaproteobacteria,1KIUX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	gcdH	-	1.3.8.6	ko:K00252	ko00071,ko00310,ko00362,ko00380,ko01100,ko01120,ko01130,map00071,map00310,map00362,map00380,map01100,map01120,map01130	M00032	R02487,R02488,R10074	RC00052,RC00156	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_3162381_3	706587.Desti_4219	1.208e-185	586.0	COG1883@1|root,COG1883@2|Bacteria,1MV0G@1224|Proteobacteria,42MH1@68525|delta/epsilon subdivisions,2WJD7@28221|Deltaproteobacteria,2MQ5Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Na+-transporting oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
PYH2_k127_3162381_14	1121405.dsmv_2550	2.255e-17	84.0	COG4770@1|root,COG4770@2|Bacteria,1NCKN@1224|Proteobacteria,42W8Y@68525|delta/epsilon subdivisions,2WRW7@28221|Deltaproteobacteria,2MM43@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Biotin-requiring enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
PYH2_k127_3162381_4	1125863.JAFN01000001_gene3100	8.021e-173	550.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42NHU@68525|delta/epsilon subdivisions,2WIZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	1.3.99.32	ko:K16173	ko00362,ko01120,map00362,map01120	-	R05579	RC00052	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_3162381_0	1187851.A33M_2769	2.101e-292	911.0	COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria	1224|Proteobacteria	I	PFAM carboxyl transferase	gcdA	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Carboxyl_trans
PYH2_k127_3162381_1	1265502.KB905930_gene1446	5.683e-283	877.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,4AACS@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	bclA_1	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_3162381_10	864051.BurJ1DRAFT_0749	1.786e-65	232.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,2VMBB@28216|Betaproteobacteria,1KM05@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH2_k127_3162381_9	864051.BurJ1DRAFT_0748	3.375e-71	246.0	2CDFS@1|root,32RXQ@2|Bacteria,1N09V@1224|Proteobacteria,2VR7P@28216|Betaproteobacteria,1KKUQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2946)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2944
PYH2_k127_3162381_5	1265502.KB905955_gene450	4.144e-146	476.0	COG0429@1|root,COG0429@2|Bacteria,1MWV1@1224|Proteobacteria,2VHZ1@28216|Betaproteobacteria,4AAFQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	hydrolase of the alpha	-	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
PYH2_k127_3162381_11	1265502.KB905955_gene451	1.987e-59	212.0	COG4319@1|root,COG4319@2|Bacteria,1MZK9@1224|Proteobacteria,2VU96@28216|Betaproteobacteria,4AE1B@80864|Comamonadaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
PYH2_k127_3162381_17	314265.R2601_23685	0.0001912	48.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2U6J3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	MA20_09680	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
PYH2_k127_3162381_15	1000565.METUNv1_03384	5.364e-16	80.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2VQNP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PYH2_k127_3162381_13	420662.Mpe_A3548	3.043e-35	143.0	COG5343@1|root,COG5343@2|Bacteria,1N821@1224|Proteobacteria,2VSFF@28216|Betaproteobacteria,1KM8C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
PYH2_k127_3162381_12	1286631.X805_40790	4.005e-51	184.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,1KKPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
PYH2_k127_3164814_1	1123504.JQKD01000041_gene2839	3.992e-33	134.0	COG0346@1|root,COG0346@2|Bacteria,1RD81@1224|Proteobacteria,2VQA3@28216|Betaproteobacteria,4ADJ6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_3
PYH2_k127_3164814_0	420662.Mpe_A0187	1.649e-118	388.0	COG0384@1|root,COG0384@2|Bacteria,1MUAS@1224|Proteobacteria,2VHM0@28216|Betaproteobacteria,1KK8X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	phenazine biosynthesis protein PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
PYH2_k127_3164814_4	670487.Ocepr_1477	0.0002045	45.0	COG1167@1|root,COG1167@2|Bacteria,1WI26@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
PYH2_k127_3164814_3	1380394.JADL01000010_gene4101	5.695e-13	70.0	COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria,2UFSH@28211|Alphaproteobacteria,2JUW5@204441|Rhodospirillales	204441|Rhodospirillales	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH2_k127_3164814_2	296591.Bpro_4235	1.973e-20	91.0	COG0697@1|root,COG0697@2|Bacteria,1MVHN@1224|Proteobacteria,2VI21@28216|Betaproteobacteria,4AD5E@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_3180339_1	420662.Mpe_A2453	2.214e-72	253.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,1KJ8Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
PYH2_k127_3180339_0	1265502.KB905930_gene1490	2.14e-223	698.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,4ABMU@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the aspartokinase family	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
PYH2_k127_3196994_1	987059.RBXJA2T_04103	8.917e-163	519.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2WGJY@28216|Betaproteobacteria,1KJQ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
PYH2_k127_3196994_0	864051.BurJ1DRAFT_4800	4.05e-190	600.0	COG0402@1|root,COG0402@2|Bacteria,1MUPT@1224|Proteobacteria,2VJN1@28216|Betaproteobacteria,1KJPU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Guanine deaminase	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PYH2_k127_3212351_2	1040989.AWZU01000015_gene2693	3.288e-10	66.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,3JTQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,Guanylate_cyc,SAM_1,Trans_reg_C
PYH2_k127_3212351_1	589865.DaAHT2_2660	1.602e-16	88.0	COG1416@1|root,COG1416@2|Bacteria,1N64N@1224|Proteobacteria,433R0@68525|delta/epsilon subdivisions,2WY2N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3212351_0	338969.Rfer_1129	9.826e-73	253.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VJF9@28216|Betaproteobacteria,4A9WE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
PYH2_k127_3212868_2	365044.Pnap_1535	7.893e-52	186.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,4ADAK@80864|Comamonadaceae	28216|Betaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH2_k127_3212868_0	1163409.UUA_04623	7.676e-93	314.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,1T095@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
PYH2_k127_3212868_1	365044.Pnap_1533	1.088e-52	190.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,4AES2@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
PYH2_k127_3212868_3	640512.BC1003_0634	4.156e-43	158.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,2VU18@28216|Betaproteobacteria,1K873@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
PYH2_k127_3229550_0	420662.Mpe_A0461	7.377e-174	557.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,1KJE5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
PYH2_k127_3229550_1	420662.Mpe_A0460	3.239e-28	115.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,1KKFN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
PYH2_k127_3239384_3	563192.HMPREF0179_02360	2.892e-24	107.0	COG0730@1|root,COG0730@2|Bacteria,1NAFA@1224|Proteobacteria,42Y8A@68525|delta/epsilon subdivisions,2WU4U@28221|Deltaproteobacteria,2MBAN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
PYH2_k127_3239384_1	1411123.JQNH01000001_gene3809	7.55e-176	583.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2TQND@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_3239384_0	1003200.AXXA_26620	1.416e-237	748.0	COG1574@1|root,COG1574@2|Bacteria,1MWP2@1224|Proteobacteria,2VJTY@28216|Betaproteobacteria,3T39N@506|Alcaligenaceae	28216|Betaproteobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
PYH2_k127_3239384_2	595537.Varpa_4443	2.289e-87	304.0	COG0523@1|root,COG0523@2|Bacteria,1MVXC@1224|Proteobacteria,2VI7N@28216|Betaproteobacteria,4ACNN@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM cobalamin synthesis protein P47K	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
PYH2_k127_3256670_3	93220.LV28_10470	4.622e-29	122.0	2BX6S@1|root,324B7@2|Bacteria,1RJA2@1224|Proteobacteria,2VTEW@28216|Betaproteobacteria,1K1XP@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1439
PYH2_k127_3256670_0	420662.Mpe_A1046	5.461e-135	435.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,1KIVR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
PYH2_k127_3256670_1	864051.BurJ1DRAFT_2860	4.87e-97	323.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,1KJ2F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
PYH2_k127_3256670_2	296591.Bpro_4848	1.785e-51	190.0	COG3821@1|root,COG3821@2|Bacteria,1PPR3@1224|Proteobacteria,2VR42@28216|Betaproteobacteria,4AHJE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF599	-	-	-	-	-	-	-	-	-	-	-	-	DUF599
PYH2_k127_3263884_0	748247.AZKH_1968	0.0	1256.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,2KVRF@206389|Rhodocyclales	206389|Rhodocyclales	S	exporters of the RND superfamily	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
PYH2_k127_3265725_4	543728.Vapar_3817	5.381e-19	87.0	COG2188@1|root,COG2188@2|Bacteria,1R790@1224|Proteobacteria,2VKB7@28216|Betaproteobacteria,4AGM9@80864|Comamonadaceae	28216|Betaproteobacteria	K	UTRA domain	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
PYH2_k127_3265725_0	381666.PHG414	1.247e-188	602.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,1K2X8@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PYH2_k127_3265725_2	1286631.X805_12670	6.144e-144	461.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,1KJJK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
PYH2_k127_3265725_1	420662.Mpe_A1081	1.355e-168	533.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJU2@28216|Betaproteobacteria,1KIWQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the arginase family	rocF	-	3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7	ko:K01476,ko:K01480,ko:K12255,ko:K18459	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157,R01990	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
PYH2_k127_3265725_3	395495.Lcho_1821	5.529e-36	139.0	COG4274@1|root,COG4274@2|Bacteria,1N29P@1224|Proteobacteria,2WFXY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
PYH2_k127_326754_5	983917.RGE_27420	6.381e-05	46.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,1KJCE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	-	-	-	-	-	-	-	-	-	-	Carb_kinase,YjeF_N
PYH2_k127_326754_0	987059.RBXJA2T_17981	0.0	1109.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,1KJ8G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
PYH2_k127_326754_2	987059.RBXJA2T_17976	1.065e-97	323.0	COG2236@1|root,COG2236@2|Bacteria,1R675@1224|Proteobacteria,2VPZG@28216|Betaproteobacteria,1KJ4V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Phosphoribosyl transferase domain	gpt	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
PYH2_k127_326754_1	1265502.KB905935_gene3053	3.258e-250	776.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,4AAS1@80864|Comamonadaceae	28216|Betaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
PYH2_k127_326754_3	864051.BurJ1DRAFT_2946	4.275e-66	229.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,1KKAN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
PYH2_k127_3278501_2	338969.Rfer_2800	2.331e-65	226.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,4AD4V@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	korC	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
PYH2_k127_3278501_0	1265502.KB905936_gene2707	0.0	1145.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,4ABU3@80864|Comamonadaceae	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
PYH2_k127_3278501_3	1144325.PMI22_03433	2.5e-28	119.0	COG3744@1|root,COG3744@2|Bacteria,1NA89@1224|Proteobacteria,1T0BF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
PYH2_k127_3278501_4	196367.JNFG01000034_gene7515	2.025e-19	90.0	COG4118@1|root,COG4118@2|Bacteria,1N7BG@1224|Proteobacteria,2VY0B@28216|Betaproteobacteria,1K9M1@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
PYH2_k127_3278501_1	1100720.ALKN01000026_gene1697	5.395e-88	292.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,4AGKN@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_3299948_20	296591.Bpro_4489	2.161e-28	117.0	COG3087@1|root,COG3087@2|Bacteria,1RI6A@1224|Proteobacteria,2VR10@28216|Betaproteobacteria,4ADFH@80864|Comamonadaceae	28216|Betaproteobacteria	D	PFAM Sporulation domain protein	ftsN	-	-	-	-	-	-	-	-	-	-	-	SPOR
PYH2_k127_3299948_11	420662.Mpe_A0151	1.546e-78	273.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,1KKVA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Thiol disulfide interchange protein	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin
PYH2_k127_3299948_15	987059.RBXJA2T_13249	1.572e-64	228.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,1KM9V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
PYH2_k127_3299948_9	983917.RGE_46040	2.984e-128	416.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,1KJJM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_3299948_2	420662.Mpe_A0148	3.837e-218	689.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,1KJHW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
PYH2_k127_3299948_7	1286631.X805_27980	1.782e-168	539.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,1KIVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the methyltransferase superfamily	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
PYH2_k127_3299948_23	1123367.C666_14215	6.44e-10	61.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2VKPZ@28216|Betaproteobacteria,2KW84@206389|Rhodocyclales	206389|Rhodocyclales	EGP	COG0477 Permeases of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
PYH2_k127_3299948_22	395495.Lcho_2320	2.571e-11	67.0	COG0477@1|root,COG2814@2|Bacteria,1MW59@1224|Proteobacteria,2VKPZ@28216|Betaproteobacteria,1KJEW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
PYH2_k127_3299948_18	864051.BurJ1DRAFT_0819	4.138e-40	153.0	COG3753@1|root,COG3753@2|Bacteria,1N7FF@1224|Proteobacteria,2VVTK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF937
PYH2_k127_3299948_13	987059.RBXJA2T_13284	2.838e-68	240.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,1KKWC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
PYH2_k127_3299948_0	864051.BurJ1DRAFT_0816	2.529e-297	920.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,1KJIN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
PYH2_k127_3299948_1	395495.Lcho_0425	7.341e-259	802.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,1KK1R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
PYH2_k127_3299948_17	395495.Lcho_0426	9.283e-48	172.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2VSM2@28216|Betaproteobacteria,1KM6D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
PYH2_k127_3299948_4	983917.RGE_46140	5.927e-193	609.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,1KJ4C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
PYH2_k127_3299948_14	365046.Rta_02070	1.017e-64	228.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,4ADXS@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PYH2_k127_3299948_6	522306.CAP2UW1_1649	4.149e-176	581.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,2VMYG@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Multidrug ABC transporter permease	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_3299948_3	522306.CAP2UW1_1648	3.155e-197	621.0	COG4591@1|root,COG4591@2|Bacteria,1QXNJ@1224|Proteobacteria,2WHVE@28216|Betaproteobacteria	28216|Betaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_3299948_10	522306.CAP2UW1_1647	4.085e-115	375.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VIKP@28216|Betaproteobacteria	28216|Betaproteobacteria	V	abc transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_3299948_8	522306.CAP2UW1_1646	7.688e-146	477.0	COG0845@1|root,COG0845@2|Bacteria,1MUMV@1224|Proteobacteria,2VIYG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
PYH2_k127_3299948_5	1223521.BBJX01000002_gene2910	2.382e-181	582.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,4AA3J@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
PYH2_k127_3299948_16	1265502.KB905951_gene846	1.571e-55	203.0	COG1765@1|root,COG1765@2|Bacteria,1N1RR@1224|Proteobacteria,2VRNP@28216|Betaproteobacteria,4AE6Y@80864|Comamonadaceae	28216|Betaproteobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
PYH2_k127_3299948_19	864051.BurJ1DRAFT_4921	1.564e-38	152.0	COG1937@1|root,COG1937@2|Bacteria,1PUF5@1224|Proteobacteria,2VVJA@28216|Betaproteobacteria,1KMC3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
PYH2_k127_3299948_21	338969.Rfer_3758	8.225e-23	102.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,2VVV9@28216|Betaproteobacteria,4AFPU@80864|Comamonadaceae	28216|Betaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
PYH2_k127_3299948_12	987059.RBXJA2T_13384	3.972e-73	248.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,1KJIC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
PYH2_k127_3339782_3	1265502.KB905930_gene1429	9.085e-65	246.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2VS5T@28216|Betaproteobacteria,4AJE7@80864|Comamonadaceae	28216|Betaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3339782_0	864051.BurJ1DRAFT_3729	3.429e-162	518.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI7D@28216|Betaproteobacteria,1KJW3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldo/keto reductase family	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PYH2_k127_3339782_2	626418.bglu_1g29220	1.489e-71	262.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,2VQAY@28216|Betaproteobacteria,1K2NU@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ebsC	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
PYH2_k127_3339782_1	983917.RGE_24190	3.581e-97	321.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,2VKHP@28216|Betaproteobacteria,1KKWV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ABC-2 family transporter protein	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
PYH2_k127_3353869_0	420662.Mpe_A1537	1.078e-283	878.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,1KJEJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
PYH2_k127_3353869_3	864051.BurJ1DRAFT_2491	5.944e-86	287.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,1KK9V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
PYH2_k127_3353869_5	864051.BurJ1DRAFT_2492	1.107e-45	168.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,1KM8T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
PYH2_k127_3353869_1	1286631.X805_37350	1.561e-239	744.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,1KJTU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM Aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH2_k127_3353869_2	983917.RGE_32590	3.472e-225	719.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,1KJ3I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
PYH2_k127_3353869_4	420662.Mpe_A1542	2.597e-63	219.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,1KK4V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
PYH2_k127_3365650_0	338969.Rfer_0504	1.84e-83	283.0	COG0642@1|root,COG0642@2|Bacteria,1QTSX@1224|Proteobacteria,2W1JF@28216|Betaproteobacteria,4A9VC@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
PYH2_k127_3365650_1	767817.Desgi_1125	2.1e-47	178.0	COG1014@1|root,COG1014@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia	186801|Clostridia	C	oxidoreductase gamma subunit	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,POR
PYH2_k127_3365650_2	767817.Desgi_1126	1.025e-36	152.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer4,Fer4_20,Pyr_redox_2,Pyr_redox_3
PYH2_k127_3387404_1	864051.BurJ1DRAFT_3646	1.122e-70	244.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,2VRFJ@28216|Betaproteobacteria,1KNPF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	HP	ATPases associated with a variety of cellular activities	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
PYH2_k127_3387404_3	296591.Bpro_0144	7.745e-51	199.0	COG0346@1|root,COG0346@2|Bacteria,1RHD4@1224|Proteobacteria,2VSJM@28216|Betaproteobacteria,4AEJT@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
PYH2_k127_3387404_0	1265502.KB905929_gene2226	0.0	1114.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,4AAMH@80864|Comamonadaceae	28216|Betaproteobacteria	J	TIGRFAM glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
PYH2_k127_3387404_5	296591.Bpro_3349	3.665e-17	89.0	2EJZ2@1|root,33DPN@2|Bacteria,1NIRT@1224|Proteobacteria,2VYGC@28216|Betaproteobacteria,4AFXX@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PXPV
PYH2_k127_3387404_4	596153.Alide_3065	2.015e-20	94.0	COG2972@1|root,COG2972@2|Bacteria,1R15V@1224|Proteobacteria,2WHZJ@28216|Betaproteobacteria,4AK3V@80864|Comamonadaceae	28216|Betaproteobacteria	T	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
PYH2_k127_3387404_2	987059.RBXJA2T_15168	2.908e-70	241.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2VM19@28216|Betaproteobacteria,1KNDW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
PYH2_k127_3424971_5	522306.CAP2UW1_0151	3.085e-99	330.0	295V5@1|root,2ZT65@2|Bacteria,1REG0@1224|Proteobacteria,2VVZW@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3424971_8	243365.CV_1441	4.405e-25	116.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,2VKI0@28216|Betaproteobacteria,2KQSB@206351|Neisseriales	206351|Neisseriales	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
PYH2_k127_3424971_4	1158292.JPOE01000002_gene2259	3.231e-109	367.0	COG1024@1|root,COG1024@2|Bacteria,1PBA3@1224|Proteobacteria,2VMRH@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_3424971_0	1223521.BBJX01000001_gene756	5.647e-236	746.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2VJYZ@28216|Betaproteobacteria,4AC18@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_3424971_1	864051.BurJ1DRAFT_4435	3.358e-150	493.0	COG0697@1|root,COG0697@2|Bacteria,1PB22@1224|Proteobacteria,2VYG5@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_3424971_7	420662.Mpe_A2298	1.593e-34	150.0	2CMMQ@1|root,32SF4@2|Bacteria,1N5EJ@1224|Proteobacteria,2VVB7@28216|Betaproteobacteria,1KMK3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3424971_2	420662.Mpe_A2299	1.438e-128	417.0	COG4727@1|root,COG4727@2|Bacteria,1R6TR@1224|Proteobacteria,2VKYF@28216|Betaproteobacteria,1KJUQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2145
PYH2_k127_3424971_10	1003200.AXXA_20993	1.079e-06	55.0	COG0500@1|root,COG2226@2|Bacteria,1QU8Z@1224|Proteobacteria,2VHJ6@28216|Betaproteobacteria,3T3ZK@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
PYH2_k127_3424971_11	159450.NH14_08370	4.337e-05	46.0	COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2VMGM@28216|Betaproteobacteria,1K282@119060|Burkholderiaceae	28216|Betaproteobacteria	ET	SMART extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PYH2_k127_3424971_9	365046.Rta_20260	3.154e-14	72.0	COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2VMGM@28216|Betaproteobacteria,4ABY0@80864|Comamonadaceae	28216|Betaproteobacteria	ET	SMART Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PYH2_k127_3424971_6	365046.Rta_20260	1.223e-47	177.0	COG0834@1|root,COG0834@2|Bacteria,1N2RR@1224|Proteobacteria,2VMGM@28216|Betaproteobacteria,4ABY0@80864|Comamonadaceae	28216|Betaproteobacteria	ET	SMART Extracellular solute-binding protein, family 3	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PYH2_k127_3424971_3	338969.Rfer_3313	4.311e-117	385.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,2VMWQ@28216|Betaproteobacteria,4AGZP@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
PYH2_k127_342609_7	864051.BurJ1DRAFT_2637	2.577e-39	150.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,1KJWV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
PYH2_k127_342609_0	983917.RGE_26100	7.873e-144	463.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,1KJYW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
PYH2_k127_342609_3	1286631.X805_08410	1.791e-80	277.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,1KKNX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
PYH2_k127_342609_2	1538295.JY96_01160	4.161e-94	325.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,1KJ9P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
PYH2_k127_342609_4	983917.RGE_26070	1.322e-61	214.0	COG3215@1|root,COG3215@2|Bacteria,1RGWZ@1224|Proteobacteria,2VT2B@28216|Betaproteobacteria,1KKYE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	pilus assembly	pilZ	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
PYH2_k127_342609_1	1268622.AVS7_01881	4.103e-114	375.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,4AAED@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM hydrolase, TatD family	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
PYH2_k127_342609_5	1265502.KB905940_gene2974	1.093e-56	207.0	COG0666@1|root,COG0666@2|Bacteria,1N952@1224|Proteobacteria,2VPIV@28216|Betaproteobacteria,4ADCG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Ankyrin	arp3	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
PYH2_k127_342609_8	1538295.JY96_01145	3.479e-14	76.0	2EK1M@1|root,33DS3@2|Bacteria,1NGUU@1224|Proteobacteria,2VY7G@28216|Betaproteobacteria,1KMTV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_342609_9	266264.Rmet_5587	6.113e-13	76.0	2E7II@1|root,3320V@2|Bacteria,1N91Y@1224|Proteobacteria,2VW18@28216|Betaproteobacteria,1K8QZ@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_342609_6	1123504.JQKD01000002_gene3986	1.857e-51	192.0	COG1801@1|root,COG1801@2|Bacteria,1MXIQ@1224|Proteobacteria,2VJWC@28216|Betaproteobacteria,4ABFA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
PYH2_k127_3447471_0	420662.Mpe_A3062	1.359e-160	518.0	COG3434@1|root,COG3434@2|Bacteria,1MVW1@1224|Proteobacteria,2VKZY@28216|Betaproteobacteria,1KJJQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	signal transduction protein containing EAL and modified HD-GYP domains	-	-	-	-	-	-	-	-	-	-	-	-	EAL,HDOD
PYH2_k127_3447471_1	420662.Mpe_A3063	4.349e-75	258.0	COG1344@1|root,COG1344@2|Bacteria,1PJUJ@1224|Proteobacteria,2VM4I@28216|Betaproteobacteria,1KK2H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Belongs to the bacterial flagellin family	flgL	-	-	ko:K02397	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_N
PYH2_k127_3479137_1	1265502.KB905949_gene960	6.163e-15	78.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,4AAXV@80864|Comamonadaceae	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
PYH2_k127_3479137_0	864051.BurJ1DRAFT_4426	4.853e-224	700.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,1KIV5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
PYH2_k127_3479137_2	864051.BurJ1DRAFT_4427	3.253e-09	59.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,1KJ0C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PYH2_k127_3505395_1	1458357.BG58_28310	1.006e-98	331.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,2VKSZ@28216|Betaproteobacteria,1K5PF@119060|Burkholderiaceae	28216|Betaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
PYH2_k127_3505395_6	391735.Veis_2526	9.232e-23	101.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHC7@28216|Betaproteobacteria,4AC92@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve
PYH2_k127_3505395_2	1408444.JHYC01000017_gene1956	1.151e-90	310.0	COG0623@1|root,COG0623@2|Bacteria,1N64Z@1224|Proteobacteria,1T3N8@1236|Gammaproteobacteria,1JC7V@118969|Legionellales	118969|Legionellales	I	KR domain	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_3505395_4	344747.PM8797T_12848	2.628e-67	237.0	COG1028@1|root,COG1028@2|Bacteria,2IXE0@203682|Planctomycetes	203682|Planctomycetes	IQ	with different specificities (related to short-chain alcohol	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_3505395_5	272624.lpg0359	2.895e-36	151.0	COG0236@1|root,COG0236@2|Bacteria,1NM9E@1224|Proteobacteria,1SINP@1236|Gammaproteobacteria,1JEJN@118969|Legionellales	118969|Legionellales	IQ	Phosphopantetheine attachment site	acpP_2	-	-	-	-	-	-	-	-	-	-	-	PP-binding
PYH2_k127_3505395_7	1230343.CANP01000023_gene1488	1.217e-21	105.0	COG0764@1|root,COG0764@2|Bacteria,1PCKD@1224|Proteobacteria,1SXNH@1236|Gammaproteobacteria,1JDAD@118969|Legionellales	118969|Legionellales	I	FabA-like domain	fabA	-	-	-	-	-	-	-	-	-	-	-	FabA
PYH2_k127_3505395_0	1230343.CANP01000023_gene1489	4.356e-135	451.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JDCZ@118969|Legionellales	118969|Legionellales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PYH2_k127_3505395_3	1094715.CM001373_gene2810	1.695e-67	248.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,1RMDE@1236|Gammaproteobacteria,1JD6F@118969|Legionellales	118969|Legionellales	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PYH2_k127_350632_0	864051.BurJ1DRAFT_4556	0.0	1658.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ2M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	AcrB/AcrD/AcrF family	acrD	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
PYH2_k127_350632_1	744980.TRICHSKD4_0401	2.8e-321	992.0	COG1653@1|root,COG1653@2|Bacteria,1MV8A@1224|Proteobacteria,2TTPV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1653 ABC-type sugar transport system, periplasmic component	MA20_44770	-	-	ko:K17321	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	SBP_bac_1,SBP_bac_8
PYH2_k127_350632_2	1144932.ATTF01000001_gene202	4.237e-19	91.0	COG3839@1|root,COG3839@2|Bacteria,1MX8G@1224|Proteobacteria,2TSXF@28211|Alphaproteobacteria,4BP6W@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC transporter	glpS	-	-	ko:K17324	ko02010,map02010	M00607	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.35	-	-	ABC_tran,TOBE_2
PYH2_k127_3513533_1	864051.BurJ1DRAFT_2854	7.24e-179	565.0	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2VK8I@28216|Betaproteobacteria,1KJ2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
PYH2_k127_3513533_3	1410620.SHLA_107c000080	1.13e-74	259.0	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,2TS3C@28211|Alphaproteobacteria,4BMKG@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
PYH2_k127_3513533_2	1286631.X805_06250	3.527e-169	565.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJHD@28216|Betaproteobacteria,1KK1M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.7	ko:K12255	ko00330,ko01100,map00330,map01100	-	R01990	RC00024,RC00329	ko00000,ko00001,ko01000	-	-	-	Arginase
PYH2_k127_3513533_0	365044.Pnap_2636	1.913e-236	739.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHGR@28216|Betaproteobacteria,4A9Q8@80864|Comamonadaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_3533333_1	864051.BurJ1DRAFT_2081	5.643e-133	449.0	COG2301@1|root,COG2301@2|Bacteria,1Q91U@1224|Proteobacteria,2VJJY@28216|Betaproteobacteria,1KJMT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
PYH2_k127_3533333_0	1265502.KB905929_gene2257	1.031e-183	578.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,4AA24@80864|Comamonadaceae	28216|Betaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
PYH2_k127_3533333_2	1538295.JY96_17985	1.059e-113	375.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,2VJ6N@28216|Betaproteobacteria,1KJ1W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	UTRA	frlR	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
PYH2_k127_3540184_3	1265502.KB905930_gene1504	9.466e-10	68.0	COG0664@1|root,COG0664@2|Bacteria,1RE4X@1224|Proteobacteria,2VMCY@28216|Betaproteobacteria,4ABJ0@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_3540184_1	420662.Mpe_A1950	1.251e-89	301.0	COG0406@1|root,COG0406@2|Bacteria,1R62X@1224|Proteobacteria,2VKQ1@28216|Betaproteobacteria,1KN3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PYH2_k127_3540184_0	864051.BurJ1DRAFT_2719	1.083e-91	308.0	COG1024@1|root,COG1024@2|Bacteria,1P3FI@1224|Proteobacteria,2VHYZ@28216|Betaproteobacteria,1KKZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	paaG2	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_3540184_2	983917.RGE_29200	7.368e-19	92.0	COG3170@1|root,COG3170@2|Bacteria,1R5KB@1224|Proteobacteria,2VMU6@28216|Betaproteobacteria,1KJDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3582950_0	983917.RGE_09390	2.632e-134	433.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,1KJGC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
PYH2_k127_3582950_5	1265502.KB905949_gene951	9.878e-12	69.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,4AD57@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
PYH2_k127_3582950_4	1410619.SRDD_35840	2.746e-20	96.0	COG0583@1|root,COG0583@2|Bacteria,1R6HA@1224|Proteobacteria,1RPV4@1236|Gammaproteobacteria,40061@613|Serratia	1236|Gammaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_3582950_2	1268622.AVS7_00465	4.414e-93	324.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2VMC0@28216|Betaproteobacteria,4ABMQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_3582950_3	1265502.KB905930_gene1450	2.159e-82	295.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2VMYA@28216|Betaproteobacteria,4AC90@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_3582950_1	398578.Daci_4486	8.509e-94	319.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VJQX@28216|Betaproteobacteria,4AA32@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3582950_6	1265502.KB905930_gene1448	9.054e-08	53.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,4ACRR@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3600704_1	420662.Mpe_A1226	2.174e-66	230.0	COG0457@1|root,COG0457@2|Bacteria,1NB8N@1224|Proteobacteria,2W9UY@28216|Betaproteobacteria,1KNVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
PYH2_k127_3600704_3	420662.Mpe_A1227	4.355e-37	141.0	2AHZN@1|root,318CZ@2|Bacteria,1Q06K@1224|Proteobacteria,2W4WA@28216|Betaproteobacteria,1KNW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3600704_0	864051.BurJ1DRAFT_1738	4.957e-105	344.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,2W1K9@28216|Betaproteobacteria,1KN6K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
PYH2_k127_3600704_2	864051.BurJ1DRAFT_1737	7.106e-59	208.0	COG0848@1|root,COG0848@2|Bacteria,1RHI8@1224|Proteobacteria,2W2ZB@28216|Betaproteobacteria,1KNMZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
PYH2_k127_3600704_4	864051.BurJ1DRAFT_1736	4.927e-25	112.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,2W30E@28216|Betaproteobacteria,1KNKV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
PYH2_k127_3621831_8	395495.Lcho_4200	4.803e-27	110.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,2VKJX@28216|Betaproteobacteria,1KJ2U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH2_k127_3621831_6	864051.BurJ1DRAFT_0507	3.482e-103	343.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,1KJKY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
PYH2_k127_3621831_5	420662.Mpe_A3378	3.025e-111	364.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,1KK48@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Phosphate acyltransferases	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PYH2_k127_3621831_7	420662.Mpe_A3379	7.268e-81	274.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,1KKN0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_like,PNK3P
PYH2_k127_3621831_0	983917.RGE_43660	6.61e-299	932.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,1KIYN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
PYH2_k127_3621831_2	1265502.KB905934_gene3282	6.151e-174	554.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,4ABB7@80864|Comamonadaceae	28216|Betaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
PYH2_k127_3621831_3	983917.RGE_43680	4.705e-170	551.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,1KJ0S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
PYH2_k127_3621831_4	983917.RGE_43690	8.467e-135	436.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,1KK97@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
PYH2_k127_3621831_1	864051.BurJ1DRAFT_0500	6.251e-184	592.0	COG0523@1|root,COG0523@2|Bacteria,1MVZV@1224|Proteobacteria,2VIHH@28216|Betaproteobacteria,1KK5M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Cobalamin synthesis protein	yjiA_1	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
PYH2_k127_3662670_7	864051.BurJ1DRAFT_0285	3.776e-61	213.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,1KJU4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
PYH2_k127_3662670_9	1247649.D560_3700	1.072e-60	221.0	2C5U9@1|root,318BZ@2|Bacteria,1RK4D@1224|Proteobacteria,2VTKM@28216|Betaproteobacteria,3T91Z@506|Alcaligenaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
PYH2_k127_3662670_8	1265502.KB905960_gene296	3.862e-61	211.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,4AE4W@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
PYH2_k127_3662670_2	864051.BurJ1DRAFT_0288	9.62e-243	760.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,1KJ18@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
PYH2_k127_3662670_6	204773.HEAR1463	1.112e-105	350.0	COG3473@1|root,COG3473@2|Bacteria,1N3F7@1224|Proteobacteria,2VH0K@28216|Betaproteobacteria,476XA@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Catalyzes the conversion of maleate to fumarate	maiA	-	5.2.1.1	ko:K01799	ko00650,ko00760,ko01120,map00650,map00760,map01120	M00622	R01087	RC00448	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_Glu_race
PYH2_k127_3662670_10	266265.Bxe_A2729	1.243e-52	190.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VK33@28216|Betaproteobacteria,1K3BT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM pyruvate carboxyltransferase	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
PYH2_k127_3662670_12	1121943.KB899991_gene2635	9.017e-21	106.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,1RMUX@1236|Gammaproteobacteria,1XN8T@135619|Oceanospirillales	135619|Oceanospirillales	E	HMGL-like	-	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
PYH2_k127_3662670_4	795666.MW7_2208	4.73e-199	628.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,1K17R@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
PYH2_k127_3662670_11	398578.Daci_1295	6.587e-50	184.0	COG3181@1|root,COG3181@2|Bacteria,1N1ND@1224|Proteobacteria,2VKD0@28216|Betaproteobacteria,4ABBA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_3662670_14	1100720.ALKN01000007_gene2997	9.83e-10	62.0	COG3181@1|root,COG3181@2|Bacteria,1N1ND@1224|Proteobacteria,2VKD0@28216|Betaproteobacteria,4ABBA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_3662670_13	420324.KI912020_gene7417	1.79e-11	68.0	COG0583@1|root,COG0583@2|Bacteria,1N3XX@1224|Proteobacteria,2TS9T@28211|Alphaproteobacteria,1JRNG@119045|Methylobacteriaceae	28211|Alphaproteobacteria	K	PFAM regulatory protein LysR	-	-	-	ko:K11921	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_3662670_1	420662.Mpe_A0173	3.588e-261	808.0	COG0189@1|root,COG0189@2|Bacteria,1QVU3@1224|Proteobacteria,2WH5E@28216|Betaproteobacteria,1KIV9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	HJ	Glutamate-cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
PYH2_k127_3662670_0	420662.Mpe_A0174	1.333e-319	987.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,1KJ7D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
PYH2_k127_3662670_15	1219375.CM002139_gene81	3.999e-05	49.0	COG3135@1|root,COG3135@2|Bacteria,1MUS1@1224|Proteobacteria,1RMD5@1236|Gammaproteobacteria,1X567@135614|Xanthomonadales	135614|Xanthomonadales	Q	protein involved in benzoate metabolism	benE	-	-	ko:K05782	-	-	-	-	ko00000,ko02000	2.A.46.1	-	-	BenE
PYH2_k127_3662670_5	395495.Lcho_3909	6.766e-156	498.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,2VIZ3@28216|Betaproteobacteria,1KIXR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
PYH2_k127_3662670_3	1265502.KB905960_gene288	5.571e-224	706.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,4AA2X@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM ABC transporter related	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PYH2_k127_3673309_0	870187.Thini_1082	1.031e-59	228.0	COG1462@1|root,COG1462@2|Bacteria,1QZPG@1224|Proteobacteria,1SH3T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	curli production assembly transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3673309_1	1121101.HMPREF1532_01662	2.113e-14	83.0	COG3595@1|root,COG3595@2|Bacteria,4NSAQ@976|Bacteroidetes,2FPF9@200643|Bacteroidia,4AMYW@815|Bacteroidaceae	976|Bacteroidetes	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
PYH2_k127_3688350_3	1280953.HOC_08092	1.296e-50	183.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,43Y7G@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes	-	-	1.13.11.82	ko:K11159,ko:K21822	-	-	-	-	ko00000,ko01000	-	-	-	RPE65
PYH2_k127_3688350_2	580332.Slit_1739	4.12e-93	335.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MWHK@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	cyaG2	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,NTP_transf_9
PYH2_k127_3688350_0	1100720.ALKN01000045_gene176	1.379e-159	507.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,4A9R8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_3688350_4	1123392.AQWL01000007_gene981	1.969e-34	135.0	COG2920@1|root,COG2920@2|Bacteria,1PZB9@1224|Proteobacteria,2W6PM@28216|Betaproteobacteria,1KT7U@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrC like protein	-	-	-	-	-	-	-	-	-	-	-	-	DsrC
PYH2_k127_3688350_1	864051.BurJ1DRAFT_4617	1.915e-139	448.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2VNJ6@28216|Betaproteobacteria,1KN3N@119065|unclassified Burkholderiales	1224|Proteobacteria	E	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
PYH2_k127_3708881_0	596153.Alide_2726	0.0	1740.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,4A9J4@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
PYH2_k127_3708881_1	395495.Lcho_2049	7.12e-216	687.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,1KIT0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	CusF_Ec,HlyD_D23,HlyD_D4
PYH2_k127_3708881_2	395495.Lcho_2050	7.129e-108	360.0	COG1538@1|root,COG1538@2|Bacteria,1NW1T@1224|Proteobacteria,2VQKM@28216|Betaproteobacteria,1KKCJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
PYH2_k127_3727254_1	338969.Rfer_2145	8.118e-56	204.0	COG0204@1|root,COG0236@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0236@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,4AB3C@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,Acyltransferase,PP-binding
PYH2_k127_3727254_2	338969.Rfer_0408	6.425e-28	118.0	2E1DK@1|root,32WSU@2|Bacteria,1N3VJ@1224|Proteobacteria,2VV0D@28216|Betaproteobacteria,4AFV5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3727254_0	296591.Bpro_0928	6.02e-119	387.0	COG2404@1|root,COG2404@2|Bacteria,1QWB5@1224|Proteobacteria,2VK0T@28216|Betaproteobacteria,4ACE9@80864|Comamonadaceae	28216|Betaproteobacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3777437_3	358220.C380_04140	4.573e-85	283.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VNEZ@28216|Betaproteobacteria,4AJ3N@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	yeiT	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
PYH2_k127_3777437_4	358220.C380_04135	1.968e-77	275.0	COG1309@1|root,COG1309@2|Bacteria,1ND64@1224|Proteobacteria,2WET9@28216|Betaproteobacteria,4ADSN@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
PYH2_k127_3777437_6	1128421.JAGA01000002_gene1413	2.875e-50	190.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc
PYH2_k127_3777437_7	1079460.ATTQ01000001_gene5759	2.138e-47	181.0	COG0633@1|root,COG2114@1|root,COG2146@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,COG2146@2|Bacteria,1N5XC@1224|Proteobacteria	1224|Proteobacteria	CT	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Guanylate_cyc,Rieske
PYH2_k127_3777437_10	1079460.ATTQ01000001_gene5759	1.707e-25	111.0	COG0633@1|root,COG2114@1|root,COG2146@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,COG2146@2|Bacteria,1N5XC@1224|Proteobacteria	1224|Proteobacteria	CT	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Guanylate_cyc,Rieske
PYH2_k127_3777437_11	1079460.ATTQ01000001_gene5759	6.107e-19	94.0	COG0633@1|root,COG2114@1|root,COG2146@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,COG2146@2|Bacteria,1N5XC@1224|Proteobacteria	1224|Proteobacteria	CT	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Guanylate_cyc,Rieske
PYH2_k127_3777437_2	1163617.SCD_n02577	1.005e-107	356.0	COG0697@1|root,COG0697@2|Bacteria,1MXJ6@1224|Proteobacteria,2VIA7@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_3777437_5	404589.Anae109_4238	2.895e-63	222.0	COG2030@1|root,COG2030@2|Bacteria,1RJN8@1224|Proteobacteria	1224|Proteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
PYH2_k127_3777437_9	864051.BurJ1DRAFT_2043	5.429e-35	139.0	COG3193@1|root,COG3193@2|Bacteria,1RH9E@1224|Proteobacteria,2VT15@28216|Betaproteobacteria,1KMD6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
PYH2_k127_3777437_1	1454004.AW11_02632	1.577e-122	403.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VMKT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PYH2_k127_3777437_0	1042326.AZNV01000044_gene703	2.408e-136	442.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,4B93F@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	Sulfate permease and related transporters (MFS superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
PYH2_k127_3777998_2	864051.BurJ1DRAFT_4903	9.784e-82	278.0	COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,2VH5J@28216|Betaproteobacteria,1KK19@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PBP superfamily domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_1,PBP_like
PYH2_k127_3777998_4	114615.BRADO1461	1.373e-68	246.0	COG0834@1|root,COG2010@1|root,COG0834@2|Bacteria,COG2010@2|Bacteria,1MVR7@1224|Proteobacteria,2TVH7@28211|Alphaproteobacteria,3JRDC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	CET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,SBP_bac_3
PYH2_k127_3777998_0	1038860.AXAP01000017_gene2906	1.098e-234	738.0	COG4993@1|root,COG4993@2|Bacteria,1MUQX@1224|Proteobacteria,2TS2Q@28211|Alphaproteobacteria,3JRZ3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ
PYH2_k127_3777998_3	395495.Lcho_1800	9.934e-74	261.0	2CWJC@1|root,32SZT@2|Bacteria,1N5QU@1224|Proteobacteria,2VPCS@28216|Betaproteobacteria,1KKF9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3777998_5	420662.Mpe_A2593	6.495e-59	208.0	2E53F@1|root,32ZWJ@2|Bacteria,1N6KB@1224|Proteobacteria,2VRMT@28216|Betaproteobacteria,1KM01@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3777998_1	864051.BurJ1DRAFT_1104	9.654e-98	322.0	28NA5@1|root,2ZBDZ@2|Bacteria,1MXY5@1224|Proteobacteria,2VMFN@28216|Betaproteobacteria,1KKFX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3777998_6	420662.Mpe_A2591	9.95e-55	194.0	COG0811@1|root,COG0811@2|Bacteria,1PPAP@1224|Proteobacteria,2VUN4@28216|Betaproteobacteria,1KMAW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
PYH2_k127_3794807_12	1255043.TVNIR_3350	1.199e-18	93.0	COG0517@1|root,COG0517@2|Bacteria	2|Bacteria	S	IMP dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBS
PYH2_k127_3794807_2	338969.Rfer_0390	2.615e-78	267.0	COG2823@1|root,COG2823@2|Bacteria,1RA8T@1224|Proteobacteria,2VRH6@28216|Betaproteobacteria,4AE8X@80864|Comamonadaceae	28216|Betaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
PYH2_k127_3794807_8	395495.Lcho_0903	2.87e-54	203.0	COG0664@1|root,COG0664@2|Bacteria,1RIZ0@1224|Proteobacteria,2VSK2@28216|Betaproteobacteria,1KNGZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_3794807_1	395495.Lcho_0902	1.134e-78	298.0	COG3852@1|root,COG4585@1|root,COG3852@2|Bacteria,COG4585@2|Bacteria,1R43J@1224|Proteobacteria,2VPEB@28216|Betaproteobacteria,1KMD2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
PYH2_k127_3794807_4	395495.Lcho_0901	1.237e-68	243.0	COG2197@1|root,COG2197@2|Bacteria,1RENN@1224|Proteobacteria,2VR4J@28216|Betaproteobacteria,1KM8B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH2_k127_3794807_10	296591.Bpro_1197	3.266e-38	149.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VR37@28216|Betaproteobacteria,4AHRU@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_3794807_13	296591.Bpro_1203	1.765e-12	74.0	2C95V@1|root,34B1R@2|Bacteria,1P1M0@1224|Proteobacteria,2W4P3@28216|Betaproteobacteria,4AIHU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
PYH2_k127_3794807_11	903814.ELI_4422	1.453e-33	147.0	2CE4Q@1|root,2Z7WX@2|Bacteria,1V1JQ@1239|Firmicutes,24G4E@186801|Clostridia,25W12@186806|Eubacteriaceae	186801|Clostridia	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans
PYH2_k127_3794807_6	987059.RBXJA2T_10079	5.362e-62	222.0	COG2913@1|root,COG2913@2|Bacteria,1N0IW@1224|Proteobacteria,2VUU7@28216|Betaproteobacteria,1KMJT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3794807_3	322710.Avin_00790	1.422e-71	246.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,1S8KZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
PYH2_k127_3794807_9	557599.MKAN_01050	1.138e-45	175.0	2DQ16@1|root,334AZ@2|Bacteria,2IMJY@201174|Actinobacteria,23A9M@1762|Mycobacteriaceae	201174|Actinobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
PYH2_k127_3794807_14	1121004.ATVC01000034_gene2252	4.968e-08	62.0	2EJ6D@1|root,33CXK@2|Bacteria,1NHGW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3794807_7	1158762.KB898038_gene2071	6.358e-55	209.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
PYH2_k127_3794807_0	420662.Mpe_A3793	2.324e-312	971.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VP2B@28216|Betaproteobacteria,1KJK7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Peptidase C39 family	cvaB	-	-	ko:K13409	ko02010,ko04626,map02010,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.110	-	-	ABC_membrane,ABC_tran,Peptidase_C39
PYH2_k127_3794807_5	420662.Mpe_A3794	1.54e-62	220.0	COG0845@1|root,COG0845@2|Bacteria,1R3R4@1224|Proteobacteria,2VJDS@28216|Betaproteobacteria,1KM1W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	HlyD family secretion protein	cvaA	-	-	ko:K13408	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
PYH2_k127_3797036_3	1265502.KB905959_gene271	4.861e-102	336.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,4AF1E@80864|Comamonadaceae	28216|Betaproteobacteria	L	Uracil DNA glycosylase superfamily	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
PYH2_k127_3797036_0	420662.Mpe_A0304	1.548e-244	775.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KK8G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9
PYH2_k127_3797036_1	420662.Mpe_A0557	1.672e-210	663.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,1KJ21@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
PYH2_k127_3797036_5	983917.RGE_04810	9.789e-82	283.0	2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,2VR1F@28216|Betaproteobacteria,1KKTB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3797036_7	987059.RBXJA2T_17871	1.875e-45	171.0	2C0PG@1|root,330E3@2|Bacteria,1RA6M@1224|Proteobacteria,2VU13@28216|Betaproteobacteria,1KMG8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
PYH2_k127_3797036_2	987059.RBXJA2T_17866	4.934e-146	469.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,1KJ0F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
PYH2_k127_3797036_6	381666.H16_A0259	5.729e-63	219.0	COG1539@1|root,COG1539@2|Bacteria,1MY5Q@1224|Proteobacteria,2VRBR@28216|Betaproteobacteria,1K79P@119060|Burkholderiaceae	28216|Betaproteobacteria	H	dihydroneopterin aldolase	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
PYH2_k127_3797036_4	420662.Mpe_A0552	4.677e-90	301.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,1KIZY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	short-chain	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_3798011_1	983917.RGE_41720	8.834e-79	264.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,1KJJG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
PYH2_k127_3798011_0	420662.Mpe_A2730	1.901e-165	526.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,2VK2N@28216|Betaproteobacteria,1KIT7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
PYH2_k127_3798011_2	420662.Mpe_A2731	8.131e-67	229.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria,1KJP0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
PYH2_k127_379986_0	1265502.KB905943_gene2727	2.822e-143	458.0	COG0108@1|root,COG0108@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,4A9S0@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
PYH2_k127_379986_1	338969.Rfer_2667	2.322e-80	273.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,4AA7Q@80864|Comamonadaceae	28216|Betaproteobacteria	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
PYH2_k127_379986_2	395495.Lcho_2934	8.12e-61	214.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,1KJU9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
PYH2_k127_3801161_0	1057002.KB905370_gene4587	4.995e-122	410.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2V7KJ@28211|Alphaproteobacteria,4BJYD@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PYH2_k127_3817091_0	526225.Gobs_3434	2.629e-19	88.0	COG0397@1|root,COG0397@2|Bacteria,2GNRX@201174|Actinobacteria,4ERYZ@85013|Frankiales	201174|Actinobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
PYH2_k127_3818981_6	864051.BurJ1DRAFT_3934	9.633e-25	104.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,1KM9S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sporulation related domain	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
PYH2_k127_3818981_5	864051.BurJ1DRAFT_3933	1.274e-45	173.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,1KM7I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
PYH2_k127_3818981_0	1265502.KB905929_gene2279	1.375e-271	842.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,4AASC@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
PYH2_k127_3818981_3	395495.Lcho_1689	1.266e-206	650.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,1KJJ8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
PYH2_k127_3818981_2	864051.BurJ1DRAFT_3930	1.841e-214	674.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,1KJPY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
PYH2_k127_3818981_9	1502770.JQMG01000001_gene2057	1.568e-07	54.0	2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3818981_10	1408444.JHYC01000008_gene1427	5.972e-05	45.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3818981_1	543728.Vapar_3488	2.537e-222	694.0	COG2942@1|root,COG2942@2|Bacteria,1MX1J@1224|Proteobacteria,2VKG0@28216|Betaproteobacteria,4AA4S@80864|Comamonadaceae	28216|Betaproteobacteria	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
PYH2_k127_3818981_4	420662.Mpe_A3796	9.669e-79	270.0	COG2771@1|root,COG2771@2|Bacteria,1R05Y@1224|Proteobacteria,2WF1E@28216|Betaproteobacteria,1KKYH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Autoinducer binding domain	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	Autoind_bind,GerE
PYH2_k127_3818981_7	543728.Vapar_2258	4.629e-19	86.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,4AAP5@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
PYH2_k127_3827397_0	864051.BurJ1DRAFT_3904	1.258e-234	733.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,1KKIQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
PYH2_k127_3827397_1	864051.BurJ1DRAFT_3903	5.433e-97	319.0	COG3090@1|root,COG3090@2|Bacteria,1R7TV@1224|Proteobacteria,2VPJP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH2_k127_3829598_3	1211115.ALIQ01000145_gene1042	3.117e-112	372.0	COG1028@1|root,COG1028@2|Bacteria,1MX30@1224|Proteobacteria,2TR09@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH2_k127_3829598_1	1502851.FG93_03072	2.84e-203	641.0	COG0683@1|root,COG0683@2|Bacteria,1N11P@1224|Proteobacteria,2TRQ4@28211|Alphaproteobacteria,3JVI6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_3829598_2	883078.HMPREF9695_01410	2.181e-133	430.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2U0TW@28211|Alphaproteobacteria,3JUC4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3829598_0	1502851.FG93_03074	0.0	1176.0	COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1R9IW@1224|Proteobacteria,2TWGB@28211|Alphaproteobacteria,3K6KK@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EG	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH2_k127_3829598_4	1411123.JQNH01000001_gene3179	1.722e-10	64.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
PYH2_k127_3840833_4	338969.Rfer_2674	2.152e-38	145.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,2VKUS@28216|Betaproteobacteria,4ABB2@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Tol-Pal system TolA	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
PYH2_k127_3840833_0	864051.BurJ1DRAFT_1555	7.741e-143	463.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,2VJR6@28216|Betaproteobacteria,1KMR3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PYH2_k127_3840833_2	864051.BurJ1DRAFT_1554	1.666e-67	245.0	292MF@1|root,32CTK@2|Bacteria,1RJGD@1224|Proteobacteria,2VSMH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
PYH2_k127_3840833_1	864051.BurJ1DRAFT_3479	4.572e-80	280.0	COG0398@1|root,COG0398@2|Bacteria,1RBAE@1224|Proteobacteria,2VP38@28216|Betaproteobacteria,1KN8D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function, DUF547	-	-	-	-	-	-	-	-	-	-	-	-	DUF547
PYH2_k127_3840833_3	395495.Lcho_1709	3.277e-57	199.0	COG0398@1|root,COG1249@1|root,COG0398@2|Bacteria,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VH3T@28216|Betaproteobacteria,1KJUI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	merA	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim,SNARE_assoc
PYH2_k127_3841708_2	1265502.KB905949_gene951	6.883e-68	238.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,4AD57@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
PYH2_k127_3841708_1	264198.Reut_B4743	5.757e-170	543.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,1K1F3@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH2_k127_3841708_0	365046.Rta_12270	3.607e-197	621.0	COG0477@1|root,COG2814@2|Bacteria,1MW19@1224|Proteobacteria,2VHTW@28216|Betaproteobacteria,4AAJM@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	TIGRFAM Drug resistance transporter Bcr CflA subfamily	bcr	-	-	ko:K07552	-	-	-	-	ko00000,ko02000	2.A.1.2	-	-	MFS_1
PYH2_k127_3867161_3	748247.AZKH_0196	2.378e-25	108.0	COG2045@1|root,COG2045@2|Bacteria,1N3KG@1224|Proteobacteria,2VR4U@28216|Betaproteobacteria,2KWE8@206389|Rhodocyclales	206389|Rhodocyclales	H	2-phosphosulpholactate phosphatase	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
PYH2_k127_3867161_5	472759.Nhal_2247	7.162e-17	94.0	2E9MH@1|root,333U5@2|Bacteria,1NDRZ@1224|Proteobacteria,1STW7@1236|Gammaproteobacteria,1X1JP@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3867161_0	622637.KE124774_gene1697	3.771e-96	324.0	COG3378@1|root,COG3378@2|Bacteria	2|Bacteria	KL	Phage plasmid primase P4 family	-	-	-	ko:K06919	-	-	-	-	ko00000	-	-	-	D5_N,P22_AR_N,PriCT_1,Prim-Pol
PYH2_k127_3867161_4	391735.Veis_4015	3.239e-25	107.0	2EU10@1|root,33MI2@2|Bacteria,1NPW2@1224|Proteobacteria,2W6GT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3867161_2	420662.Mpe_A1531	4.246e-33	131.0	2EBAD@1|root,335AZ@2|Bacteria,1N6VF@1224|Proteobacteria,2VWWE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3869646_2	1279038.KB907341_gene1837	8.409e-86	297.0	COG1409@1|root,COG1409@2|Bacteria,1MV0H@1224|Proteobacteria,2TZMG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3869646_0	1265502.KB905933_gene2029	0.0	1075.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,4A9M6@80864|Comamonadaceae	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
PYH2_k127_3869646_1	420662.Mpe_A1163	4.971e-198	621.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,1KK2J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
PYH2_k127_3869646_3	420662.Mpe_A1164	6.744e-69	239.0	2DBXD@1|root,2ZBP6@2|Bacteria,1RB44@1224|Proteobacteria,2VQT3@28216|Betaproteobacteria,1KKYG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3305
PYH2_k127_3869646_4	1286631.X805_15720	4.012e-40	161.0	2DNW4@1|root,32ZGA@2|Bacteria,1N7ZK@1224|Proteobacteria,2VWJH@28216|Betaproteobacteria,1KM21@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3306)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3306
PYH2_k127_3870487_6	987059.RBXJA2T_06950	2.099e-104	344.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,1KJ36@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
PYH2_k127_3870487_2	420662.Mpe_A0847	2.675e-221	712.0	COG3170@1|root,COG3170@2|Bacteria,1QV1N@1224|Proteobacteria,2WGRZ@28216|Betaproteobacteria,1KJQ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
PYH2_k127_3870487_8	338969.Rfer_2428	8.862e-68	235.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,2VT9K@28216|Betaproteobacteria,4ADW1@80864|Comamonadaceae	28216|Betaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
PYH2_k127_3870487_7	1265502.KB905938_gene2465	7.684e-97	320.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,4AAIY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
PYH2_k127_3870487_1	420662.Mpe_A0850	9.301e-255	791.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,1KK8K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
PYH2_k127_3870487_5	420662.Mpe_A0851	8.044e-128	412.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,1KJS7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Cytochrome C1	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
PYH2_k127_3870487_4	987059.RBXJA2T_06980	3.999e-128	410.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,1KKCU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glutathione S-transferase	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
PYH2_k127_3870487_9	864051.BurJ1DRAFT_1236	5.23e-61	214.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,1KKTI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
PYH2_k127_3870487_11	661478.OP10G_0131	0.0006373	44.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PYH2_k127_3870487_10	395495.Lcho_0743	9.174e-18	87.0	COG4701@1|root,COG4701@2|Bacteria,1N5G9@1224|Proteobacteria,2VU6Y@28216|Betaproteobacteria,1KMHI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
PYH2_k127_3870487_3	864051.BurJ1DRAFT_1239	6.245e-135	437.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,1KIZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	peptidase	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
PYH2_k127_3870487_0	983917.RGE_10540	0.0	1365.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,1KITH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
PYH2_k127_3874294_0	745310.G432_17440	4.722e-123	400.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria,2K007@204457|Sphingomonadales	204457|Sphingomonadales	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PYH2_k127_3874294_5	1007103.AFHW01000116_gene3714	0.0002221	53.0	COG2246@1|root,COG2246@2|Bacteria,1VJC6@1239|Firmicutes,4HNMS@91061|Bacilli,26XMX@186822|Paenibacillaceae	91061|Bacilli	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
PYH2_k127_3874294_2	216591.BCAS0225	1.213e-23	103.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VS0H@28216|Betaproteobacteria,1KD9X@119060|Burkholderiaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_3874294_1	397945.Aave_1026	6.024e-52	202.0	2B90Y@1|root,322BP@2|Bacteria,1N0TB@1224|Proteobacteria,2WGC7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3874294_3	1317118.ATO8_20996	1.436e-16	82.0	COG0463@1|root,COG0463@2|Bacteria,1MXC1@1224|Proteobacteria,2TVY5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PYH2_k127_3874778_1	420662.Mpe_A1972	3.492e-86	289.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,1KJM6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
PYH2_k127_3874778_0	420662.Mpe_A1971	0.0	1168.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,1KJ34@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
PYH2_k127_3874778_2	987059.RBXJA2T_18046	6.097e-65	226.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,1KKYP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the skp family	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
PYH2_k127_3874778_3	1000565.METUNv1_01290	3.193e-07	53.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,2KVNR@206389|Rhodocyclales	206389|Rhodocyclales	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
PYH2_k127_3876368_2	596154.Alide2_0571	5.81e-28	123.0	2CDKX@1|root,32RXZ@2|Bacteria,1RKGY@1224|Proteobacteria,2VUJ5@28216|Betaproteobacteria,4AG4V@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4387)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4387
PYH2_k127_3876368_3	1268622.AVS7_03518	2.23e-14	82.0	COG3181@1|root,COG3181@2|Bacteria,1N7C4@1224|Proteobacteria,2VHNI@28216|Betaproteobacteria,4A9W4@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_3876368_1	504728.K649_10265	1.62e-86	291.0	COG0286@1|root,COG0286@2|Bacteria,1WJAF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
PYH2_k127_3876368_4	926566.Terro_3081	2.478e-11	74.0	2DMPM@1|root,32SWT@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3876368_0	946483.Cenrod_1741	1.605e-123	399.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2VNF8@28216|Betaproteobacteria,4AG4P@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PYH2_k127_3880170_2	1000565.METUNv1_00433	4.63e-56	200.0	COG3235@1|root,COG3235@2|Bacteria,1RDMZ@1224|Proteobacteria,2WFSM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3880170_1	1159870.KB907784_gene3297	9.368e-96	329.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VM54@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM class II aldolase adducin family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
PYH2_k127_3880170_0	1123240.ATVO01000009_gene788	2.359e-140	453.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0GU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
PYH2_k127_3887084_2	983917.RGE_24420	1.827e-99	327.0	COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2VH22@28216|Betaproteobacteria,1KKCH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	KR domain	gno1	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
PYH2_k127_3887084_4	420662.Mpe_A1780	1.338e-49	181.0	COG2050@1|root,COG2050@2|Bacteria,1MYG1@1224|Proteobacteria,2VTQD@28216|Betaproteobacteria,1KM5T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH2_k127_3887084_1	420662.Mpe_A1781	4.572e-168	534.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2VIE7@28216|Betaproteobacteria,1KJUY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
PYH2_k127_3887084_3	987059.RBXJA2T_08855	1.914e-54	209.0	COG2153@1|root,COG2153@2|Bacteria,1MZHA@1224|Proteobacteria,2VTYH@28216|Betaproteobacteria,1KMFG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	elaA	-	-	ko:K02348	-	-	-	-	ko00000	-	-	-	Acetyltransf_10
PYH2_k127_3887084_0	1265502.KB905940_gene2991	5.64e-210	666.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VHMA@28216|Betaproteobacteria,4A9UE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
PYH2_k127_3887895_2	864051.BurJ1DRAFT_2925	4.871e-93	307.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,1KK6E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
PYH2_k127_3887895_3	365044.Pnap_1769	3.736e-67	240.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,4ADIB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
PYH2_k127_3887895_1	1265502.KB905935_gene3036	5.119e-121	393.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,4AB4E@80864|Comamonadaceae	28216|Betaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
PYH2_k127_3887895_0	1265502.KB905935_gene3035	2.694e-154	494.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,4A9M3@80864|Comamonadaceae	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
PYH2_k127_3901395_3	1231391.AMZF01000020_gene2010	3.863e-118	417.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUFT@1224|Proteobacteria	1224|Proteobacteria	E	(ABC) transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_3901395_2	1231391.AMZF01000020_gene2009	3.815e-119	389.0	COG0559@1|root,COG0559@2|Bacteria,1P3FU@1224|Proteobacteria,2VPYC@28216|Betaproteobacteria,3T2PS@506|Alcaligenaceae	28216|Betaproteobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3901395_1	1231391.AMZF01000020_gene2008	9.122e-158	528.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria	1224|Proteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_3901395_0	1028800.RG540_CH00970	4.292e-176	558.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,4BDWB@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
PYH2_k127_3901395_4	1157708.KB907457_gene2576	1.054e-43	163.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,4ACE5@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM iron-containing alcohol dehydrogenase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
PYH2_k127_3905312_7	76114.ebA2062	3.395e-57	224.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,2WGS8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH2_k127_3905312_2	76114.ebA2060	2.477e-284	889.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,2KV3E@206389|Rhodocyclales	28216|Betaproteobacteria	I	Methylmalonyl-CoA mutase	icmF	-	5.4.99.2,5.4.99.63,5.4.99.64	ko:K01847,ko:K01848,ko:K14447,ko:K20906	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R00833,R09292	RC00395,RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
PYH2_k127_3905312_6	76114.ebD52	1.985e-63	219.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,2VW7W@28216|Betaproteobacteria	28216|Betaproteobacteria	I	B12 binding domain	-	-	5.4.99.2,5.4.99.64	ko:K01849,ko:K20907	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
PYH2_k127_3905312_5	76114.ebA2055	2.019e-193	610.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,2KVJQ@206389|Rhodocyclales	206389|Rhodocyclales	C	COG1960 Acyl-CoA dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_3905312_1	76114.ebA2053	0.0	1047.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VITF@28216|Betaproteobacteria,2KXQJ@206389|Rhodocyclales	206389|Rhodocyclales	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
PYH2_k127_3905312_0	76114.ebA2051	0.0	1197.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,2KY97@206389|Rhodocyclales	206389|Rhodocyclales	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
PYH2_k127_3905312_3	76114.ebA2050	2.109e-215	682.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria,2KW5T@206389|Rhodocyclales	206389|Rhodocyclales	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_3905312_4	76114.ebA2049	7.426e-215	683.0	COG0183@1|root,COG0183@2|Bacteria,1MXYM@1224|Proteobacteria	1224|Proteobacteria	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_3905312_9	1244869.H261_12246	1.632e-43	163.0	COG2030@1|root,COG2030@2|Bacteria,1RD6F@1224|Proteobacteria,2UC91@28211|Alphaproteobacteria,2JUFA@204441|Rhodospirillales	204441|Rhodospirillales	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
PYH2_k127_3905312_8	1244869.H261_14125	4.301e-45	167.0	COG2030@1|root,COG2030@2|Bacteria,1RJ2Z@1224|Proteobacteria,2U5QB@28211|Alphaproteobacteria,2JTHA@204441|Rhodospirillales	204441|Rhodospirillales	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
PYH2_k127_3905312_10	76114.ebA2047	1.695e-30	122.0	COG1802@1|root,COG1802@2|Bacteria,1RISU@1224|Proteobacteria,2VVD4@28216|Betaproteobacteria	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_3912264_3	365046.Rta_17120	2.231e-64	235.0	COG3971@1|root,COG3971@2|Bacteria,1RGHI@1224|Proteobacteria,2VRTF@28216|Betaproteobacteria,4AE62@80864|Comamonadaceae	28216|Betaproteobacteria	Q	2-Keto-4-pentenoate hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
PYH2_k127_3912264_0	987059.RBXJA2T_18488	9.827e-218	691.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,1KKEE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
PYH2_k127_3912264_1	983917.RGE_35320	3.762e-166	527.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,1KIYE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
PYH2_k127_3912264_4	1265502.KB905941_gene2929	1.9e-56	200.0	COG1047@1|root,COG1047@2|Bacteria,1RHD1@1224|Proteobacteria,2VRJ4@28216|Betaproteobacteria,4ADNQ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	fkpB	-	5.2.1.8	ko:K03774	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
PYH2_k127_3912264_2	420662.Mpe_A2695	9.056e-94	312.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,1KJAX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
PYH2_k127_3912264_5	983917.RGE_35350	1.703e-30	134.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,1KKVS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Smr domain	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
PYH2_k127_3917506_0	1123229.AUBC01000013_gene2611	1.27e-242	759.0	COG0154@1|root,COG0410@1|root,COG0154@2|Bacteria,COG0410@2|Bacteria,1MUVQ@1224|Proteobacteria,2TU7H@28211|Alphaproteobacteria,3JSWU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	ABC_tran,Amidase
PYH2_k127_3917506_1	83219.PM02_16405	3.74e-58	208.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,3ZXAZ@60136|Sulfitobacter	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	acsf	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_3931859_13	983917.RGE_13930	1.628e-61	213.0	COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,1KIWG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the ompA family	ompA	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
PYH2_k127_3931859_8	358220.C380_13580	2.077e-115	379.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,4ACGN@80864|Comamonadaceae	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
PYH2_k127_3931859_12	983917.RGE_13950	6.287e-83	291.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria,1KKJU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	HAD-hyrolase-like	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PYH2_k127_3931859_5	420662.Mpe_A2218	1.753e-150	481.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,2VM49@28216|Betaproteobacteria,1KK9Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
PYH2_k127_3931859_10	1538295.JY96_14230	1.121e-97	335.0	COG1402@1|root,COG1402@2|Bacteria,1R4JB@1224|Proteobacteria,2VQJZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Creatinine amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Creatininase
PYH2_k127_3931859_2	1538295.JY96_14235	5.818e-198	625.0	COG3391@1|root,COG3391@2|Bacteria,1R78P@1224|Proteobacteria,2VJ7I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3931859_9	420662.Mpe_A2078	1.599e-98	334.0	COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria,1KKAS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
PYH2_k127_3931859_7	1265502.KB905931_gene1611	1.065e-128	426.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,2VHTD@28216|Betaproteobacteria,4AA7R@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM molybdopterin binding domain	yfaY	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
PYH2_k127_3931859_0	864051.BurJ1DRAFT_1439	2.123e-292	900.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,1KJNG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	glutamine synthetase	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
PYH2_k127_3931859_15	420662.Mpe_A2075	5.939e-46	171.0	2BWQ4@1|root,32QZV@2|Bacteria,1MZQ9@1224|Proteobacteria,2VSNR@28216|Betaproteobacteria,1KM87@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
PYH2_k127_3931859_3	1265502.KB905931_gene1614	2.441e-159	517.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,4AA8Q@80864|Comamonadaceae	28216|Betaproteobacteria	T	Signal transduction histidine kinase, nitrogen specific	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
PYH2_k127_3931859_1	1265502.KB905931_gene1615	1.175e-250	779.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,4AB5M@80864|Comamonadaceae	28216|Betaproteobacteria	T	TIGRFAM nitrogen regulation protein NR(I)	ntrC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
PYH2_k127_3931859_6	1265502.KB905931_gene1616	1.075e-137	440.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,4AA5T@80864|Comamonadaceae	28216|Betaproteobacteria	L	Exodeoxyribonuclease III xth	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
PYH2_k127_3931859_11	864051.BurJ1DRAFT_1451	9.529e-90	298.0	28HPC@1|root,2Z7XD@2|Bacteria,1REIX@1224|Proteobacteria,2VS60@28216|Betaproteobacteria,1KMBS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
PYH2_k127_3931859_14	420662.Mpe_A2052	9.589e-55	200.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,1KM46@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
PYH2_k127_3931859_4	1265502.KB905931_gene1625	3.03e-158	502.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,4A9KM@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
PYH2_k127_3932737_1	420662.Mpe_A1876	1.572e-198	634.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,1KJGG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K12542	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	3.A.1.109.4,8.A.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
PYH2_k127_3932737_0	864051.BurJ1DRAFT_2241	6e-323	1005.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VP2B@28216|Betaproteobacteria,1KITV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	TIGRFAM type I secretion system ATPase	-	-	-	ko:K12541	ko02010,map02010	M00330	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.3,3.A.1.109.4	-	-	ABC_membrane,ABC_tran,Peptidase_C39
PYH2_k127_3932737_3	1265502.KB905940_gene2941	3.021e-86	288.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,4ABNT@80864|Comamonadaceae	28216|Betaproteobacteria	F	Nudix hydrolase	nudC_1	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
PYH2_k127_3932737_5	1123504.JQKD01000056_gene3233	1.194e-13	75.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2VHG8@28216|Betaproteobacteria,4AA1W@80864|Comamonadaceae	28216|Betaproteobacteria	Q	fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
PYH2_k127_3932737_2	983917.RGE_23720	2.672e-110	359.0	COG0625@1|root,COG0625@2|Bacteria,1RA4Y@1224|Proteobacteria,2VKEU@28216|Betaproteobacteria,1KJCG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	maleylacetoacetate isomerase	maiA	-	5.2.1.2,5.2.1.4	ko:K01800,ko:K01801	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R03181,R03868	RC00867	ko00000,ko00001,ko00002,ko01000	-	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
PYH2_k127_3932737_4	864051.BurJ1DRAFT_2245	2.316e-27	115.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,1KKKZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
PYH2_k127_3934095_3	543728.Vapar_1228	1.97e-160	529.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,4A9RF@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH2_k127_3934095_2	595537.Varpa_1322	1.533e-161	514.0	COG0559@1|root,COG0559@2|Bacteria,1MXMC@1224|Proteobacteria,2VJ1Y@28216|Betaproteobacteria,4AASW@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_3934095_1	1286631.X805_01200	2.379e-195	629.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,2VHP9@28216|Betaproteobacteria,1KIYD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_3934095_4	1157708.KB907457_gene2730	1.506e-95	317.0	COG0778@1|root,COG0778@2|Bacteria,1PG8V@1224|Proteobacteria,2VMYY@28216|Betaproteobacteria,4ADCN@80864|Comamonadaceae	28216|Betaproteobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
PYH2_k127_3934095_0	864051.BurJ1DRAFT_3549	1.275e-289	899.0	COG0318@1|root,COG0318@2|Bacteria,1MUQZ@1224|Proteobacteria,2VIB6@28216|Betaproteobacteria,1KJKA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme	-	-	6.2.1.34	ko:K12508	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
PYH2_k127_3934095_5	1265502.KB905933_gene2116	3.887e-23	100.0	2EFGB@1|root,33990@2|Bacteria,1N7I5@1224|Proteobacteria,2VWTQ@28216|Betaproteobacteria,4AEZU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3936598_1	420662.Mpe_A0255	1.858e-157	502.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2VMYU@28216|Betaproteobacteria,1KK3T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
PYH2_k127_3936598_5	1157708.KB907457_gene2790	3.087e-37	148.0	COG5490@1|root,COG5490@2|Bacteria,1MZ74@1224|Proteobacteria,2VWIQ@28216|Betaproteobacteria,4AHSX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phasin protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
PYH2_k127_3936598_3	864051.BurJ1DRAFT_0241	6.187e-88	296.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,1KKK8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	JM	Nucleotidyl transferase	rmlA	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
PYH2_k127_3936598_4	395495.Lcho_0219	1.113e-65	230.0	COG3945@1|root,COG3945@2|Bacteria,1N12K@1224|Proteobacteria,2VUPY@28216|Betaproteobacteria,1KKSC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
PYH2_k127_3936598_6	358220.C380_22645	1.248e-35	139.0	COG1586@1|root,COG1586@2|Bacteria,1QWFT@1224|Proteobacteria,2VTEG@28216|Betaproteobacteria,4AJYS@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	2.5.1.16,4.1.1.50	ko:K00797,ko:K01611	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R00178,R01920,R02869,R08359	RC00021,RC00053,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	AdoMet_dc
PYH2_k127_3936598_0	983917.RGE_44770	0.0	1059.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,1KJAJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
PYH2_k127_3936598_7	1437824.BN940_15296	6.609e-16	87.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,3T31E@506|Alcaligenaceae	28216|Betaproteobacteria	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
PYH2_k127_3936598_8	1198452.Jab_1c15260	2.163e-06	59.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,472TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	gap	GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
PYH2_k127_3936598_2	342113.DM82_6287	7.864e-98	340.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VIXC@28216|Betaproteobacteria,1K5NA@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the peptidase S8 family	mprA	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
PYH2_k127_3937895_5	1265502.KB905952_gene805	5.845e-11	66.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2WFQ4@28216|Betaproteobacteria,4ADMI@80864|Comamonadaceae	28216|Betaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
PYH2_k127_3937895_3	395495.Lcho_4004	1.765e-44	172.0	2DPMQ@1|root,32UME@2|Bacteria,1N03M@1224|Proteobacteria,2VUEW@28216|Betaproteobacteria,1KMFB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_3937895_4	365046.Rta_13740	3.519e-25	108.0	COG2863@1|root,COG2863@2|Bacteria,1NGJ1@1224|Proteobacteria,2VVR2@28216|Betaproteobacteria,4AFCM@80864|Comamonadaceae	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
PYH2_k127_3937895_0	1265502.KB905952_gene808	1.956e-223	698.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,2VK35@28216|Betaproteobacteria,4AA1P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavocytochrome c sulphide dehydrogenase, flavin-binding	soxF	-	1.8.2.1,1.8.5.4	ko:K05301,ko:K17218	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00528,R10152	RC00168,RC03155	ko00000,ko00001,ko01000	-	-	-	FCSD-flav_bind,Pyr_redox_2,TAT_signal
PYH2_k127_3937895_2	987059.RBXJA2T_02597	4.75e-57	214.0	COG3431@1|root,COG3431@2|Bacteria,1N6PE@1224|Proteobacteria,2VQFF@28216|Betaproteobacteria,1KKUR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sensors of blue-light using FAD	-	-	-	-	-	-	-	-	-	-	-	-	BLUF
PYH2_k127_3937895_1	864051.BurJ1DRAFT_0880	9.001e-131	421.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,2VH10@28216|Betaproteobacteria,1KK20@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	GTP cyclohydrolase	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
PYH2_k127_3937895_6	864051.BurJ1DRAFT_0881	8.585e-08	54.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,1KJDF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
PYH2_k127_3956791_3	1100720.ALKN01000040_gene2177	3.245e-66	230.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VPR2@28216|Betaproteobacteria,4ADP5@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_3956791_2	1169152.AXVD01000020_gene404	2.778e-93	314.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4G8SZ@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
PYH2_k127_3956791_1	864051.BurJ1DRAFT_2300	1.818e-172	544.0	COG1878@1|root,COG1878@2|Bacteria,1MVWU@1224|Proteobacteria,2VI5X@28216|Betaproteobacteria,1KMVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
PYH2_k127_3956791_0	864051.BurJ1DRAFT_1685	5.914e-201	635.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VH80@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_3968290_4	1265502.KB905941_gene2935	7.004e-64	220.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,2VHXK@28216|Betaproteobacteria,4AANN@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM MOFRL domain protein	ttuD	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
PYH2_k127_3968290_2	864069.MicloDRAFT_00003630	1.093e-141	459.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,2TTSG@28211|Alphaproteobacteria,1JSNC@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
PYH2_k127_3968290_1	338969.Rfer_2188	3.349e-173	552.0	COG2130@1|root,COG2130@2|Bacteria,1MUC2@1224|Proteobacteria,2VJHE@28216|Betaproteobacteria,4ACC4@80864|Comamonadaceae	28216|Betaproteobacteria	S	N-terminal domain of oxidoreductase	-	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
PYH2_k127_3968290_3	1095769.CAHF01000023_gene590	4.297e-115	383.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_D23
PYH2_k127_3968290_0	1095769.CAHF01000023_gene591	0.0	1296.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,473CA@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	MMPL family	bepE	-	-	ko:K03296,ko:K18138,ko:K18902	ko01501,ko01503,map01501,map01503	M00647,M00698,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
PYH2_k127_3968290_5	1122603.ATVI01000007_gene1569	1.816e-05	57.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,1RMDA@1236|Gammaproteobacteria,1XCNQ@135614|Xanthomonadales	135614|Xanthomonadales	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
PYH2_k127_3978135_1	420662.Mpe_A0170	3.716e-139	451.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,1KJU4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
PYH2_k127_3978135_2	420662.Mpe_A0169	5.743e-35	141.0	COG3133@1|root,COG3133@2|Bacteria,1RK6D@1224|Proteobacteria,2VU04@28216|Betaproteobacteria,1KMDG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	17 kDa surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Rick_17kDa_Anti
PYH2_k127_3978135_3	1538295.JY96_14420	4.267e-12	73.0	COG4102@1|root,COG4102@2|Bacteria,1MX4R@1224|Proteobacteria,2VITU@28216|Betaproteobacteria,1KKRP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
PYH2_k127_3978135_0	395495.Lcho_3270	0.0	1522.0	COG1410@1|root,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,1KJAA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
PYH2_k127_4001386_4	420662.Mpe_A0111	4.984e-62	216.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,1KKNH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
PYH2_k127_4001386_3	243924.LT42_05925	6.331e-63	223.0	COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,1S80Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Auxin-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PYH2_k127_4001386_0	1265502.KB905937_gene2551	1.08e-295	917.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,4AAFA@80864|Comamonadaceae	28216|Betaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
PYH2_k127_4001386_2	864051.BurJ1DRAFT_3841	2.229e-71	245.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,1KM34@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
PYH2_k127_4001386_6	420662.Mpe_A0107	1.267e-23	115.0	2EFG1@1|root,3398R@2|Bacteria,1N86X@1224|Proteobacteria,2VX76@28216|Betaproteobacteria,1KMUI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4001386_1	420662.Mpe_A0105	1.591e-79	271.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,2VU1J@28216|Betaproteobacteria,1KNGP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
PYH2_k127_4003404_2	864051.BurJ1DRAFT_2511	6.488e-117	380.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,1KIX9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
PYH2_k127_4003404_1	1265502.KB905930_gene1574	3.669e-298	922.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,4AA3F@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PYH2_k127_4003404_3	864051.BurJ1DRAFT_2508	5.036e-97	335.0	28NZT@1|root,2ZBWJ@2|Bacteria,1RBSK@1224|Proteobacteria,2VQDC@28216|Betaproteobacteria,1KKKV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4003404_0	983917.RGE_32530	0.0	1461.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,1KJ9T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PYH2_k127_4003404_6	864051.BurJ1DRAFT_2501	1.189e-39	154.0	2DNXC@1|root,32ZN4@2|Bacteria,1NKWP@1224|Proteobacteria,2VX7B@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4003404_7	1249627.D779_0260	1.526e-36	143.0	COG1993@1|root,COG1993@2|Bacteria,1RH30@1224|Proteobacteria,1S7XN@1236|Gammaproteobacteria,1WYP4@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized ACR, COG1993	-	-	-	-	-	-	-	-	-	-	-	-	DUF190
PYH2_k127_4003404_5	765911.Thivi_2529	1.393e-46	170.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,1S9GR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
PYH2_k127_4003404_4	395495.Lcho_2020	1.79e-70	245.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,1KKKE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Molybdopterin biosynthesis MoaE protein	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
PYH2_k127_4016639_0	2074.JNYD01000010_gene979	1.282e-132	430.0	COG3135@1|root,COG3135@2|Bacteria,2GNQX@201174|Actinobacteria,4DYUB@85010|Pseudonocardiales	201174|Actinobacteria	Q	Benzoate membrane transport protein	benE	-	-	ko:K05782	-	-	-	-	ko00000,ko02000	2.A.46.1	-	-	BenE
PYH2_k127_4016639_1	228410.NE0481	1.005e-40	154.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,2VUG3@28216|Betaproteobacteria,3748M@32003|Nitrosomonadales	28216|Betaproteobacteria	K	plasmid maintenance system antidote protein	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
PYH2_k127_4016639_2	863365.XHC_2234	1.056e-36	140.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,1S9WR@1236|Gammaproteobacteria,1X7YI@135614|Xanthomonadales	135614|Xanthomonadales	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
PYH2_k127_4030965_9	420662.Mpe_A0241	2.809e-42	162.0	2E0TN@1|root,32WBB@2|Bacteria,1N02C@1224|Proteobacteria,2VUQU@28216|Betaproteobacteria,1KMEF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
PYH2_k127_4030965_4	864051.BurJ1DRAFT_4624	1.182e-111	376.0	COG0697@1|root,COG0697@2|Bacteria,1R6KH@1224|Proteobacteria,2VNEM@28216|Betaproteobacteria,1KJMA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_4030965_7	1286631.X805_36740	6.783e-70	239.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,2VR6S@28216|Betaproteobacteria,1KKZY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	aut	-	2.7.7.70	ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PYH2_k127_4030965_6	1504672.669783223	1.192e-88	297.0	COG0625@1|root,COG0625@2|Bacteria,1RAP2@1224|Proteobacteria,2VQGV@28216|Betaproteobacteria,4AD2P@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
PYH2_k127_4030965_2	420662.Mpe_A0239	1.817e-166	527.0	COG1633@1|root,COG1633@2|Bacteria,1MXX8@1224|Proteobacteria,2VI3H@28216|Betaproteobacteria,1KJG3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4030965_5	983917.RGE_44890	3.309e-98	330.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,1KJT9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
PYH2_k127_4030965_0	864051.BurJ1DRAFT_4627	7.795e-187	595.0	COG2907@1|root,COG2907@2|Bacteria,1MV4Z@1224|Proteobacteria,2VHCR@28216|Betaproteobacteria,1KK8T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06954	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
PYH2_k127_4030965_3	987059.RBXJA2T_02712	6.86e-123	414.0	COG3496@1|root,COG3496@2|Bacteria,1RC56@1224|Proteobacteria,2VIZ9@28216|Betaproteobacteria,1KJ9C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1365)	-	-	-	ko:K09701	-	-	-	-	ko00000	-	-	-	DUF1365
PYH2_k127_4030965_1	987059.RBXJA2T_02717	6.131e-182	580.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VJ00@28216|Betaproteobacteria,1KJWP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
PYH2_k127_4030965_8	614083.AWQR01000009_gene717	5.792e-45	172.0	COG3572@1|root,COG3572@2|Bacteria,1N0R0@1224|Proteobacteria,2VUCP@28216|Betaproteobacteria,4AEYP@80864|Comamonadaceae	28216|Betaproteobacteria	H	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
PYH2_k127_4041252_5	1265502.KB905954_gene428	1.255e-36	141.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,4ADJN@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PYH2_k127_4041252_4	1122603.ATVI01000010_gene882	3.986e-48	179.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,1S654@1236|Gammaproteobacteria,1XC4R@135614|Xanthomonadales	135614|Xanthomonadales	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
PYH2_k127_4041252_1	420662.Mpe_A1157	1.716e-121	398.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,1KJBJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
PYH2_k127_4041252_6	1265502.KB905954_gene433	2.34e-26	110.0	2E9SN@1|root,32ZFH@2|Bacteria,1N8MD@1224|Proteobacteria,2VW4H@28216|Betaproteobacteria,4AFFC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3460
PYH2_k127_4041252_3	864051.BurJ1DRAFT_0273	3.962e-50	183.0	COG2913@1|root,COG2913@2|Bacteria,1RBY9@1224|Proteobacteria,2VSW7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	(Lipo)protein	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
PYH2_k127_4041252_7	338969.Rfer_2928	4.555e-16	89.0	2EFF1@1|root,333UR@2|Bacteria,1NDN9@1224|Proteobacteria,2VXFP@28216|Betaproteobacteria,4AHVU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4041252_2	388051.AUFE01000043_gene3298	1.282e-81	289.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria,1K712@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
PYH2_k127_4041252_0	1366050.N234_08430	1.106e-215	676.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria,1K61J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
PYH2_k127_4048114_17	983917.RGE_13520	5.062e-13	70.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,1KJDN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
PYH2_k127_4048114_6	983917.RGE_13530	1.24e-117	392.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,1KJ0I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
PYH2_k127_4048114_15	1265502.KB905934_gene3208	3.71e-30	129.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria,4AEJH@80864|Comamonadaceae	28216|Betaproteobacteria	H	PFAM Transcriptional coactivator pterin dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
PYH2_k127_4048114_1	987059.RBXJA2T_05468	1.397e-185	590.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,1KJSJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Peptidase M48	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
PYH2_k127_4048114_8	983917.RGE_13550	8.161e-93	308.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,1KJIX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	A	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
PYH2_k127_4048114_13	864051.BurJ1DRAFT_3087	3.516e-40	158.0	COG3860@1|root,COG3860@2|Bacteria,1RH83@1224|Proteobacteria,2VWC6@28216|Betaproteobacteria,1KNKE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087
PYH2_k127_4048114_10	420662.Mpe_A2212	2.852e-46	169.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,1KM2Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
PYH2_k127_4048114_7	1265502.KB905934_gene3197	3.976e-111	370.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,4ABA9@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
PYH2_k127_4048114_11	1504672.669786338	4.188e-46	180.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,2VH4V@28216|Betaproteobacteria,4AB40@80864|Comamonadaceae	28216|Betaproteobacteria	S	DinB superfamily	egtB	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
PYH2_k127_4048114_9	395495.Lcho_1718	8.419e-64	228.0	COG0500@1|root,COG2226@2|Bacteria,1MZVH@1224|Proteobacteria,2VZ2M@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
PYH2_k127_4048114_5	864051.BurJ1DRAFT_1762	7.11e-132	428.0	COG2267@1|root,COG2267@2|Bacteria,1RATF@1224|Proteobacteria,2WI63@28216|Betaproteobacteria,1KJSE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
PYH2_k127_4048114_0	864051.BurJ1DRAFT_1764	0.0	1716.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,1KJE9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
PYH2_k127_4048114_12	864051.BurJ1DRAFT_1765	5.346e-41	155.0	2ATZM@1|root,31JJE@2|Bacteria,1RIFX@1224|Proteobacteria,2VSS3@28216|Betaproteobacteria,1KM95@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4048114_2	420662.Mpe_A2250	3.177e-171	546.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria,1KK15@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
PYH2_k127_4048114_14	864051.BurJ1DRAFT_1767	4.001e-35	143.0	COG1555@1|root,COG1555@2|Bacteria,1PU4R@1224|Proteobacteria,2WAPW@28216|Betaproteobacteria,1KMHW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
PYH2_k127_4048114_3	1286631.X805_37250	1.299e-161	517.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,1KKFZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
PYH2_k127_4048114_4	1286631.X805_37240	2.558e-147	475.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,1KJUV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272,ko:K21344	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
PYH2_k127_4048114_16	864051.BurJ1DRAFT_1775	4.293e-23	99.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,1KJJF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_7
PYH2_k127_4051823_0	1538295.JY96_17855	0.0	1407.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,1KJIF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
PYH2_k127_4063980_0	1286093.C266_05444	1.025e-68	235.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VIFS@28216|Betaproteobacteria,1K04V@119060|Burkholderiaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
PYH2_k127_4063980_1	292563.Cyast_2360	2.45e-12	78.0	2DVYR@1|root,33XR8@2|Bacteria,1GE1F@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_408780_13	1538295.JY96_19945	6.064e-32	128.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,1KJPQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
PYH2_k127_408780_12	1265502.KB905931_gene1773	5.902e-42	162.0	2AY9T@1|root,31QC7@2|Bacteria,1RK1R@1224|Proteobacteria,2VT1A@28216|Betaproteobacteria,4AECS@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_408780_7	420662.Mpe_A2565	4.937e-105	346.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
PYH2_k127_408780_5	864051.BurJ1DRAFT_2836	5.672e-120	411.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,1KJ9Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
PYH2_k127_408780_4	420662.Mpe_A2563	1.429e-153	489.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,1KJC8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
PYH2_k127_408780_10	864051.BurJ1DRAFT_2834	2.387e-71	246.0	COG0500@1|root,COG0500@2|Bacteria,1QU9M@1224|Proteobacteria,2WGK0@28216|Betaproteobacteria,1KM4I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
PYH2_k127_408780_6	1265502.KB905936_gene2712	5.359e-108	357.0	COG0300@1|root,COG0300@2|Bacteria,1R5VP@1224|Proteobacteria,2VK5H@28216|Betaproteobacteria,4ABK4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH2_k127_408780_2	864051.BurJ1DRAFT_2832	4.034e-204	640.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,1KK9B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_408780_1	987059.RBXJA2T_18253	1.463e-216	678.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2VH1D@28216|Betaproteobacteria,1KJ8N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	D-amino acid	dadA	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
PYH2_k127_408780_8	1380391.JIAS01000013_gene3696	4.062e-98	328.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
PYH2_k127_408780_11	1380391.JIAS01000013_gene3695	1.317e-50	188.0	COG1309@1|root,COG1309@2|Bacteria,1PJ6M@1224|Proteobacteria,2V9MS@28211|Alphaproteobacteria,2JYAP@204441|Rhodospirillales	204441|Rhodospirillales	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
PYH2_k127_408780_0	420662.Mpe_A2559	0.0	1147.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,1KJW7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
PYH2_k127_408780_9	864051.BurJ1DRAFT_2816	7.138e-74	268.0	COG1670@1|root,COG1670@2|Bacteria,1PDMH@1224|Proteobacteria,2VS7P@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
PYH2_k127_408780_3	1100720.ALKN01000026_gene1697	1.105e-180	581.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,4AGKN@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_4092523_4	522306.CAP2UW1_0898	1.56e-07	60.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,2VSZI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
PYH2_k127_4092523_1	983917.RGE_07330	3.581e-200	634.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VMJZ@28216|Betaproteobacteria,1KN20@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
PYH2_k127_4092523_0	983917.RGE_07320	1.686e-214	680.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VMJZ@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	TIGRFAM acyltransferase, WS DGAT MGAT	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
PYH2_k127_4092523_3	204773.HEAR1382	7.04e-24	111.0	COG1075@1|root,COG1075@2|Bacteria,1NJNA@1224|Proteobacteria,2VPNT@28216|Betaproteobacteria,476C4@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,PGAP1
PYH2_k127_4092523_2	1280950.HJO_00485	2.527e-162	517.0	COG3670@1|root,COG3670@2|Bacteria,1MY1X@1224|Proteobacteria,2TS7A@28211|Alphaproteobacteria,43Y7G@69657|Hyphomonadaceae	28211|Alphaproteobacteria	Q	COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes	-	-	1.13.11.82	ko:K11159,ko:K21822	-	-	-	-	ko00000,ko01000	-	-	-	RPE65
PYH2_k127_4102941_0	1538295.JY96_02460	2.204e-187	591.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,1KJPB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
PYH2_k127_4102941_2	983917.RGE_41010	4.646e-165	523.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2VJ9D@28216|Betaproteobacteria,1KJ5S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
PYH2_k127_4102941_8	983917.RGE_41000	1.224e-40	155.0	COG4969@1|root,COG4969@2|Bacteria,1N71K@1224|Proteobacteria,2VWEY@28216|Betaproteobacteria,1KMG1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
PYH2_k127_4102941_5	864051.BurJ1DRAFT_4097	5.04e-105	347.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,1KIXX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
PYH2_k127_4102941_3	1265502.KB905932_gene1825	6.648e-140	459.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,4AACD@80864|Comamonadaceae	28216|Betaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
PYH2_k127_4102941_6	420662.Mpe_A0652	9.812e-75	264.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,1KKNU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
PYH2_k127_4102941_4	395495.Lcho_0595	3.235e-116	384.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,1KJP1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
PYH2_k127_4102941_7	1265502.KB905932_gene1822	9.684e-53	202.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,4ADXB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
PYH2_k127_4102941_1	864051.BurJ1DRAFT_4092	5.635e-173	555.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,1KK4Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
PYH2_k127_4102941_9	864051.BurJ1DRAFT_4089	6.644e-28	119.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,1KJ6P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
PYH2_k127_4113956_7	1265502.KB905931_gene1653	1.593e-17	83.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,2VIM5@28216|Betaproteobacteria,4AAR3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PYH2_k127_4113956_2	983917.RGE_14810	3.837e-161	515.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,1KJ6Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
PYH2_k127_4113956_5	987059.RBXJA2T_12297	1.415e-65	232.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,1KM3G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
PYH2_k127_4113956_1	983917.RGE_14790	1.772e-179	574.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,1KJV2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
PYH2_k127_4113956_3	864051.BurJ1DRAFT_4529	2.08e-97	323.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,1KJ7C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
PYH2_k127_4113956_0	1265502.KB905931_gene1647	1.356e-233	738.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,4A9M7@80864|Comamonadaceae	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
PYH2_k127_4113956_4	987059.RBXJA2T_11987	3.031e-91	308.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VHIS@28216|Betaproteobacteria,1KPKI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	qseB	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH2_k127_4113956_6	395495.Lcho_0275	2.573e-31	132.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,1KPCK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
PYH2_k127_4123444_7	380394.Lferr_2714	2.068e-40	152.0	COG2210@1|root,COG2210@2|Bacteria,1NXM5@1224|Proteobacteria,1SREE@1236|Gammaproteobacteria,2NCZR@225057|Acidithiobacillales	225057|Acidithiobacillales	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
PYH2_k127_4123444_9	380394.Lferr_2715	1.055e-28	116.0	COG0425@1|root,COG0425@2|Bacteria,1NDVB@1224|Proteobacteria,1T176@1236|Gammaproteobacteria,2ND8U@225057|Acidithiobacillales	225057|Acidithiobacillales	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
PYH2_k127_4123444_2	743299.Acife_2633	4.434e-173	553.0	COG0446@1|root,COG0446@2|Bacteria,1N5MC@1224|Proteobacteria,1RQS1@1236|Gammaproteobacteria,2NCAJ@225057|Acidithiobacillales	225057|Acidithiobacillales	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PYH2_k127_4123444_6	637390.AFOH01000013_gene704	1.185e-47	190.0	290SD@1|root,2ZNEH@2|Bacteria,1P6XW@1224|Proteobacteria,1STK8@1236|Gammaproteobacteria,2NC0Z@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4123444_0	1366050.N234_07665	2.942e-272	846.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,2VNNI@28216|Betaproteobacteria,1K3QF@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PYH2_k127_4123444_1	864051.BurJ1DRAFT_2085	9.714e-269	832.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHZI@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Tripartite tricarboxylate transporter TctA family	-	-	-	-	-	-	-	-	-	-	-	-	TctA
PYH2_k127_4123444_8	864051.BurJ1DRAFT_2084	3.702e-32	143.0	2E6D9@1|root,3310W@2|Bacteria,1N9Y9@1224|Proteobacteria,2VWRF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
PYH2_k127_4123444_3	864051.BurJ1DRAFT_2083	4.292e-172	543.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKQJ@28216|Betaproteobacteria,1KKBI@119065|unclassified Burkholderiales	1224|Proteobacteria	S	Tripartite tricarboxylate transporter family receptor	MA20_15805	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_4123444_5	864051.BurJ1DRAFT_3896	1.129e-137	450.0	COG2084@1|root,COG2084@2|Bacteria,1MV48@1224|Proteobacteria,2VKTQ@28216|Betaproteobacteria	28216|Betaproteobacteria	I	6-phosphogluconate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
PYH2_k127_4123444_4	1276756.AUEX01000010_gene1583	5.338e-161	517.0	COG0683@1|root,COG0683@2|Bacteria,1N1MX@1224|Proteobacteria,2VJMT@28216|Betaproteobacteria,4AC97@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_4126087_0	987059.RBXJA2T_18318	2.188e-314	971.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,1KJ90@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
PYH2_k127_4187585_0	502025.Hoch_4147	3.841e-311	964.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
PYH2_k127_427332_2	748247.AZKH_1502	3.775e-128	420.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,2KUWF@206389|Rhodocyclales	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
PYH2_k127_427332_6	296591.Bpro_2639	1.985e-25	110.0	COG1917@1|root,COG1917@2|Bacteria,1RH0Y@1224|Proteobacteria,2VWWA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_427332_1	1244869.H261_06576	3.267e-210	670.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,2TUIT@28211|Alphaproteobacteria,2JRZP@204441|Rhodospirillales	204441|Rhodospirillales	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
PYH2_k127_427332_0	296591.Bpro_4279	0.0	1312.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
PYH2_k127_427332_7	338963.Pcar_0300	2.229e-23	103.0	COG1531@1|root,COG1531@2|Bacteria,1N7PM@1224|Proteobacteria,42X42@68525|delta/epsilon subdivisions,2WTGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	AJ	Protein of unknown function (DUF504)	-	-	-	-	-	-	-	-	-	-	-	-	DUF504
PYH2_k127_427332_4	338969.Rfer_1518	4.941e-75	263.0	COG2344@1|root,COG2344@2|Bacteria,1NXDK@1224|Proteobacteria,2VN87@28216|Betaproteobacteria,4ABCB@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
PYH2_k127_427332_5	269799.Gmet_2409	3.898e-53	192.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42SWA@68525|delta/epsilon subdivisions,2WPE1@28221|Deltaproteobacteria,43W0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
PYH2_k127_427332_3	296591.Bpro_4278	3.27e-117	380.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae	28216|Betaproteobacteria	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
PYH2_k127_4300529_7	987059.RBXJA2T_12934	1.347e-99	330.0	COG3503@1|root,COG3503@2|Bacteria,1RA1Q@1224|Proteobacteria,2VNUA@28216|Betaproteobacteria,1KKFQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1624)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
PYH2_k127_4300529_9	395495.Lcho_1836	2.099e-59	210.0	COG2050@1|root,COG2050@2|Bacteria,1N5HF@1224|Proteobacteria,2VQ8W@28216|Betaproteobacteria,1KM7Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH2_k127_4300529_8	338969.Rfer_1387	6.235e-78	265.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,2VQSG@28216|Betaproteobacteria,4AEAD@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
PYH2_k127_4300529_6	358220.C380_09505	4.295e-112	368.0	COG3687@1|root,COG3687@2|Bacteria,1R6G1@1224|Proteobacteria,2WFRN@28216|Betaproteobacteria,4ACGX@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted metal-dependent hydrolase	-	-	-	ko:K07044	-	-	-	-	ko00000	-	-	-	Metal_hydrol
PYH2_k127_4300529_2	983917.RGE_32960	2.249e-294	915.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,1KKG0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
PYH2_k127_4300529_4	864051.BurJ1DRAFT_2050	4.208e-149	484.0	COG2141@1|root,COG2141@2|Bacteria,1MVF0@1224|Proteobacteria,2VHXM@28216|Betaproteobacteria,1KJSV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Luciferase family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
PYH2_k127_4300529_11	1366050.N234_29725	0.000249	53.0	2DV97@1|root,33UTM@2|Bacteria,1NV4W@1224|Proteobacteria,2W1Y5@28216|Betaproteobacteria,1KDEX@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4300529_0	1265502.KB905940_gene3012	0.0	2086.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,4AARH@80864|Comamonadaceae	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
PYH2_k127_4300529_3	420662.Mpe_A1760	1.064e-151	482.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,1KJMF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Methionine aminopeptidase	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
PYH2_k127_4300529_1	1286631.X805_34180	0.0	1233.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,1KJ53@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
PYH2_k127_4300529_5	395495.Lcho_2084	3.421e-123	407.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,1KJPD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
PYH2_k127_4300529_10	1000565.METUNv1_00493	4.446e-05	54.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,2KWGH@206389|Rhodocyclales	206389|Rhodocyclales	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
PYH2_k127_4307561_0	983917.RGE_39430	7.121e-285	887.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,1KJBE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_4336297_0	1265502.KB905943_gene2746	1.632e-228	715.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,4AABM@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
PYH2_k127_4336297_1	864051.BurJ1DRAFT_1572	4.904e-73	248.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,1KKSD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
PYH2_k127_4336297_2	420662.Mpe_A2940	2.443e-51	188.0	COG4970@1|root,COG4970@2|Bacteria,1N43I@1224|Proteobacteria,2VUQM@28216|Betaproteobacteria,1KMEB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
PYH2_k127_4336297_3	864051.BurJ1DRAFT_1570	9.749e-21	98.0	COG4968@1|root,COG4968@2|Bacteria,1QDNY@1224|Proteobacteria,2W8CB@28216|Betaproteobacteria,1KMJ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
PYH2_k127_4356153_1	983917.RGE_21750	1.111e-125	423.0	COG1028@1|root,COG1028@2|Bacteria,1MWJI@1224|Proteobacteria,2VHU1@28216|Betaproteobacteria,1KKE5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_4356153_2	1265502.KB905961_gene329	9.907e-122	404.0	COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,2VJMU@28216|Betaproteobacteria,4A9V0@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Permeases of the drug metabolite transporter (DMT) superfamily	eamA1	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_4356153_0	426355.Mrad2831_0119	5.055e-179	566.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2TQWP@28211|Alphaproteobacteria,1JRFA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Gamma-glutamyltranspeptidase	ggt1	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
PYH2_k127_4364580_2	358220.C380_21620	1.872e-42	162.0	COG0589@1|root,COG0589@2|Bacteria,1N674@1224|Proteobacteria,2VTHJ@28216|Betaproteobacteria,4AEMR@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_4364580_3	765911.Thivi_0085	2.447e-23	115.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,1SEEB@1236|Gammaproteobacteria,1WZHH@135613|Chromatiales	135613|Chromatiales	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_4364580_0	365044.Pnap_0389	8.227e-252	789.0	COG0459@1|root,COG0459@2|Bacteria,1NRHG@1224|Proteobacteria,2W0NW@28216|Betaproteobacteria,4AH8I@80864|Comamonadaceae	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	-	-	-	-	-	-	-	-	-	Cpn60_TCP1
PYH2_k127_4364580_1	1121939.L861_19650	1.298e-79	273.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1XIG3@135619|Oceanospirillales	135619|Oceanospirillales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PYH2_k127_4367409_3	864051.BurJ1DRAFT_1339	4.547e-13	74.0	COG2199@1|root,COG3706@2|Bacteria,1MXAW@1224|Proteobacteria,2VK79@28216|Betaproteobacteria,1KIYC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	2.7.7.65	ko:K13590	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
PYH2_k127_4367409_0	420662.Mpe_A2857	0.0	1056.0	COG2199@1|root,COG5001@1|root,COG3706@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KK2Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_4,Response_reg
PYH2_k127_4367409_2	420662.Mpe_A2858	2.536e-13	78.0	COG0784@1|root,COG2198@1|root,COG3850@1|root,COG4251@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG3850@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,1KPMM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_4,Response_reg
PYH2_k127_4367409_1	1121918.ARWE01000001_gene2053	2.03e-43	165.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43SDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PAS domain	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
PYH2_k127_4405922_0	748280.NH8B_2766	0.0	1048.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DEAD DEAH box helicase	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
PYH2_k127_4405922_1	196367.JNFG01000011_gene6120	5.108e-279	870.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,1K4WQ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	phaC	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
PYH2_k127_4405922_12	196490.AUEZ01000002_gene4200	0.0002145	49.0	2BYAD@1|root,343KS@2|Bacteria,1N9VE@1224|Proteobacteria,2UINW@28211|Alphaproteobacteria,3K4EF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PQ-loop
PYH2_k127_4405922_8	859657.RPSI07_mp1449	5.158e-112	368.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VU4X@28216|Betaproteobacteria,1K4JW@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
PYH2_k127_4405922_3	983917.RGE_01930	2.164e-253	789.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria,1KITK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
PYH2_k127_4405922_10	420662.Mpe_A3341	7.131e-56	203.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,1KKH7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
PYH2_k127_4405922_6	395495.Lcho_0510	1.465e-146	471.0	COG0697@1|root,COG0697@2|Bacteria,1MW7P@1224|Proteobacteria,2VHDI@28216|Betaproteobacteria,1KKBB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	ytfF	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_4405922_4	1265502.KB905968_gene1258	3.158e-213	670.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VISA@28216|Betaproteobacteria,4AAZ5@80864|Comamonadaceae	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	glcF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7,Fer4_8
PYH2_k127_4405922_9	983917.RGE_01980	2.672e-88	298.0	COG0500@1|root,COG0500@2|Bacteria,1R1VS@1224|Proteobacteria,2WI6B@28216|Betaproteobacteria,1KN16@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
PYH2_k127_4405922_7	1123508.JH636444_gene5625	1.975e-112	374.0	COG4948@1|root,COG4948@2|Bacteria,2J0HB@203682|Planctomycetes	203682|Planctomycetes	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
PYH2_k127_4405922_5	1265502.KB905968_gene1257	7.349e-151	490.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,4AAAA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
PYH2_k127_4405922_2	395495.Lcho_3260	1.701e-270	843.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH8M@28216|Betaproteobacteria,1KIZS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD	-	1.1.2.4,1.1.3.15,1.1.5.12	ko:K00102,ko:K00104,ko:K03777	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475,R00704,R11591	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
PYH2_k127_4405922_11	420662.Mpe_A3636	1.031e-14	73.0	COG4398@1|root,COG4398@2|Bacteria,1MUX9@1224|Proteobacteria,2VIY7@28216|Betaproteobacteria,1KJ2J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
PYH2_k127_4407743_2	443598.AUFA01000127_gene7209	8.999e-21	92.0	COG2984@1|root,COG2984@2|Bacteria,1RDUT@1224|Proteobacteria,2U8XC@28211|Alphaproteobacteria,3JYZA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_4407743_0	1265502.KB905934_gene3247	2.394e-160	515.0	COG0599@1|root,COG2267@1|root,COG0599@2|Bacteria,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,2VJEH@28216|Betaproteobacteria,4ADNZ@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
PYH2_k127_4407743_1	864051.BurJ1DRAFT_4480	1.024e-45	170.0	COG1262@1|root,COG1262@2|Bacteria,1Q227@1224|Proteobacteria,2VSH1@28216|Betaproteobacteria,1KM5M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SapC	-	-	-	-	-	-	-	-	-	-	-	-	SapC
PYH2_k127_445381_4	983917.RGE_01850	1.247e-32	129.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,2VPBZ@28216|Betaproteobacteria,1KMZE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_445381_2	667632.KB890164_gene1874	7.012e-82	297.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VQ03@28216|Betaproteobacteria,1K2RR@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_C_3,GST_N,GST_N_3
PYH2_k127_445381_0	1254432.SCE1572_40310	4.886e-185	597.0	COG1793@1|root,COG1793@2|Bacteria,1MV3S@1224|Proteobacteria,430DD@68525|delta/epsilon subdivisions,2WVKB@28221|Deltaproteobacteria,2YUBR@29|Myxococcales	28221|Deltaproteobacteria	F	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	ligB	-	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
PYH2_k127_445381_3	996637.SGM_4595	3.128e-50	186.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PYH2_k127_445381_5	1206737.BAGF01000038_gene2067	1.427e-05	56.0	28JCJ@1|root,2Z977@2|Bacteria,2HHS9@201174|Actinobacteria,4FZVC@85025|Nocardiaceae	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
PYH2_k127_445381_1	1461693.ATO10_09273	5.837e-126	426.0	COG0682@1|root,COG0682@2|Bacteria,1R7B3@1224|Proteobacteria	1224|Proteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT,PAP2_3,PEMT
PYH2_k127_4462667_0	1265502.KB905931_gene1641	1.155e-115	381.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,4A9MG@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
PYH2_k127_4462667_2	232721.Ajs_3112	1e-75	261.0	COG1136@1|root,COG1136@2|Bacteria,1NCFC@1224|Proteobacteria,2VIQD@28216|Betaproteobacteria,4AA0Z@80864|Comamonadaceae	28216|Betaproteobacteria	V	SMART AAA ATPase	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_4462667_1	420662.Mpe_A2047	1.129e-93	315.0	COG0577@1|root,COG0577@2|Bacteria,1MVCT@1224|Proteobacteria,2VJAI@28216|Betaproteobacteria,1KJGP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_4507373_2	426114.THI_0811	0.0007327	51.0	COG0402@1|root,COG0402@2|Bacteria,1MUFE@1224|Proteobacteria,2VH0A@28216|Betaproteobacteria,1KNEI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Amidohydrolase family	hutF	-	3.5.3.13	ko:K05603	ko00340,map00340	-	R02286	RC00682	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PYH2_k127_4507373_0	987059.RBXJA2T_01490	6.486e-118	385.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2VK2Y@28216|Betaproteobacteria,1KKNY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	N-formylglutamate amidohydrolase	hutG	-	3.5.1.68,3.5.3.8	ko:K01458,ko:K01479	ko00340,ko00630,ko01100,map00340,map00630,map01100	M00045	R00525,R02285	RC00165,RC00221,RC00323,RC00681	ko00000,ko00001,ko00002,ko01000	-	-	-	FGase
PYH2_k127_4507373_1	426114.THI_0809	6.05e-88	293.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2VK8A@28216|Betaproteobacteria,1KN18@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
PYH2_k127_4512962_3	477184.KYC_09385	4.171e-52	188.0	COG0665@1|root,COG0665@2|Bacteria,1MY0G@1224|Proteobacteria,2VM19@28216|Betaproteobacteria,3T2QH@506|Alcaligenaceae	28216|Betaproteobacteria	E	Glycine D-amino acid oxidases (deaminating)	-	-	1.4.99.6	ko:K19746	ko00472,ko01100,map00472,map01100	-	R11018	RC00006	ko00000,ko00001,ko01000	-	-	-	DAO
PYH2_k127_4512962_2	1218075.BAYA01000004_gene1440	3.776e-110	365.0	COG0265@1|root,COG0265@2|Bacteria,1N58P@1224|Proteobacteria,2VS6N@28216|Betaproteobacteria,1K0TH@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
PYH2_k127_4512962_6	864051.BurJ1DRAFT_3784	1.808e-21	94.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2VKFT@28216|Betaproteobacteria,1KKZT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LytTr DNA-binding domain	lytT	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PYH2_k127_4512962_0	391735.Veis_4576	1.466e-151	485.0	COG0583@1|root,COG0583@2|Bacteria,1MU3N@1224|Proteobacteria,2VK0X@28216|Betaproteobacteria,4ADA7@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_4512962_1	391735.Veis_4577	6.175e-122	396.0	COG1540@1|root,COG1540@2|Bacteria,1MUYV@1224|Proteobacteria,2VK7Q@28216|Betaproteobacteria,4ABM0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
PYH2_k127_4512962_5	398578.Daci_0006	6.363e-27	112.0	COG0511@1|root,COG0511@2|Bacteria,1N90D@1224|Proteobacteria,2VWD6@28216|Betaproteobacteria,4AFG3@80864|Comamonadaceae	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
PYH2_k127_4512962_4	391735.Veis_4579	2.858e-32	131.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VJ2Z@28216|Betaproteobacteria,4AG8K@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	-	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
PYH2_k127_452520_2	296591.Bpro_4694	6.159e-198	620.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2VKTZ@28216|Betaproteobacteria,4AB2I@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
PYH2_k127_452520_6	296591.Bpro_4693	1.291e-62	222.0	COG1802@1|root,COG1802@2|Bacteria,1MY8X@1224|Proteobacteria,2VRYQ@28216|Betaproteobacteria,4AETD@80864|Comamonadaceae	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_452520_0	864051.BurJ1DRAFT_4436	9.087e-236	740.0	COG1283@1|root,COG1283@2|Bacteria,1MUDE@1224|Proteobacteria,2VJWM@28216|Betaproteobacteria,1KKIB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Na+/Pi-cotransporter	nptA	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
PYH2_k127_452520_3	296591.Bpro_3222	1.131e-180	573.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2VHD1@28216|Betaproteobacteria,4ACCT@80864|Comamonadaceae	28216|Betaproteobacteria	C	Alanine dehydrogenase/PNT, C-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
PYH2_k127_452520_5	864051.BurJ1DRAFT_4437	4.062e-123	401.0	COG0697@1|root,COG0697@2|Bacteria,1R46X@1224|Proteobacteria,2VNGN@28216|Betaproteobacteria,1KNKQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_452520_7	977880.RALTA_B1650	1.569e-57	216.0	COG1802@1|root,COG1802@2|Bacteria,1RE3J@1224|Proteobacteria,2VQMY@28216|Betaproteobacteria,1K585@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Phosphonate utilization associated transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_452520_1	322710.Avin_17500	1.143e-204	643.0	COG1524@1|root,COG1524@2|Bacteria,1N5SF@1224|Proteobacteria	1224|Proteobacteria	S	type I phosphodiesterase nucleotide pyrophosphatase	phnA	-	3.11.1.2	ko:K19670	ko00440,map00440	-	R00318	RC01309	ko00000,ko00001,ko01000	-	-	-	Phosphodiest
PYH2_k127_452520_4	595537.Varpa_1738	1.836e-148	484.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VIFS@28216|Betaproteobacteria,4A9PZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_4535251_0	1366050.N234_08450	1.8e-257	800.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria,1K3JX@119060|Burkholderiaceae	28216|Betaproteobacteria	CP	Proton-conducting membrane transporter	hyfB	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
PYH2_k127_4536687_8	543913.D521_0699	4.901e-05	49.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,1KQJN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Quinolinate phosphoribosyl transferase, C-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
PYH2_k127_4536687_3	1265502.KB905930_gene1577	7.106e-192	604.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,4A9N9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
PYH2_k127_4536687_6	395495.Lcho_2013	3.283e-102	347.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	-
PYH2_k127_4536687_4	1276756.AUEX01000002_gene378	1.28e-167	537.0	COG0477@1|root,COG2814@2|Bacteria,1QUTR@1224|Proteobacteria,2VHHN@28216|Betaproteobacteria,4AADR@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
PYH2_k127_4536687_1	987059.RBXJA2T_19641	8.945e-267	842.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VIEX@28216|Betaproteobacteria,1KJSK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	Belongs to the TPP enzyme family	ilvG	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_4536687_7	1504672.669787123	1.022e-68	237.0	COG0684@1|root,COG0684@2|Bacteria,1RH18@1224|Proteobacteria,2VR2C@28216|Betaproteobacteria,4AE4U@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions	rraA	-	-	ko:K02553	-	-	-	-	ko00000,ko03019	-	-	-	RraA-like
PYH2_k127_4536687_2	864051.BurJ1DRAFT_2886	2.01e-257	810.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2VJ62@28216|Betaproteobacteria,1KN36@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH2_k127_4536687_5	864051.BurJ1DRAFT_2885	7.859e-115	378.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2VKZJ@28216|Betaproteobacteria,1KJH3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	phosphoserine phosphatase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
PYH2_k127_4536687_0	1265502.KB905971_gene1290	0.0	1239.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,4AAFE@80864|Comamonadaceae	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
PYH2_k127_4646709_1	1411123.JQNH01000001_gene2375	2.642e-118	383.0	COG0329@1|root,COG0329@2|Bacteria,1MWV5@1224|Proteobacteria,2TRE1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EM	Belongs to the DapA family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
PYH2_k127_4646709_4	1037409.BJ6T_61420	1.306e-05	51.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_4646709_3	189753.AXAS01000011_gene7551	1.033e-19	95.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2URQN@28211|Alphaproteobacteria,3K6JB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
PYH2_k127_4646709_2	189753.AXAS01000041_gene2534	3.442e-22	98.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_4646709_0	614083.AWQR01000007_gene379	2.351e-250	775.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VH71@28216|Betaproteobacteria,4ABR0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.28	ko:K00141	ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667	RC00075	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_4646721_8	864051.BurJ1DRAFT_1083	1.576e-120	392.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJ0Q@28216|Betaproteobacteria,1KJHD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_4646721_0	864051.BurJ1DRAFT_1084	0.0	1097.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,1KJ66@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PYH2_k127_4646721_10	987059.RBXJA2T_17157	6.62e-101	333.0	COG0664@1|root,COG0664@2|Bacteria,1MUHT@1224|Proteobacteria,2VI43@28216|Betaproteobacteria,1KJG7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PFAM Cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_4646721_6	1100721.ALKO01000024_gene450	1.309e-152	492.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,2VJKN@28216|Betaproteobacteria,4AAV8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM 5-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
PYH2_k127_4646721_5	987059.RBXJA2T_17102	3.281e-171	542.0	COG0466@1|root,COG0466@2|Bacteria,1MWQ9@1224|Proteobacteria,2VJKY@28216|Betaproteobacteria,1KJEZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	PFAM ATPase family associated with various cellular activities (AAA)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
PYH2_k127_4646721_4	420662.Mpe_A3138	5.093e-177	562.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VM1X@28216|Betaproteobacteria,1KIZB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	general secretion pathway protein	gspF	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
PYH2_k127_4646721_2	987059.RBXJA2T_17082	3.671e-247	773.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KK8F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	TIGRFAM general secretory pathway protein E	gspE	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
PYH2_k127_4646721_1	395495.Lcho_3427	6.467e-275	863.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria,1KK85@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	general secretion pathway protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
PYH2_k127_4646721_11	864051.BurJ1DRAFT_1123	5.73e-84	296.0	28IWK@1|root,2Z8UV@2|Bacteria,1P9EC@1224|Proteobacteria,2VJZY@28216|Betaproteobacteria,1KKND@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Type II secretion system (T2SS), protein N	gspN	-	-	ko:K02463	ko05111,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSN
PYH2_k127_4646721_16	395495.Lcho_3425	1.27e-37	150.0	COG3149@1|root,COG3149@2|Bacteria,1N133@1224|Proteobacteria,2VUUD@28216|Betaproteobacteria,1KMCM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM General secretion pathway, M protein	gspM	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
PYH2_k127_4646721_7	420662.Mpe_A3133	6.656e-121	401.0	COG3297@1|root,COG3297@2|Bacteria,1MX9I@1224|Proteobacteria,2VH8V@28216|Betaproteobacteria,1KJQQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	General secretion pathway	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
PYH2_k127_4646721_9	420662.Mpe_A3132	1.344e-110	366.0	COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,2VS9P@28216|Betaproteobacteria,1KK5C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM General secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
PYH2_k127_4646721_12	420662.Mpe_A3131	1.117e-66	241.0	COG4795@1|root,COG4795@2|Bacteria,1RJBJ@1224|Proteobacteria,2WGMU@28216|Betaproteobacteria,1KM0R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Prokaryotic N-terminal methylation motif	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
PYH2_k127_4646721_14	987059.RBXJA2T_16447	1.288e-49	182.0	COG2165@1|root,COG2165@2|Bacteria,1N0C2@1224|Proteobacteria,2VVJ8@28216|Betaproteobacteria,1KM8V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	general secretion pathway protein	gspI	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
PYH2_k127_4646721_15	1265502.KB905948_gene1006	1.269e-40	157.0	COG4970@1|root,COG4970@2|Bacteria,1RIET@1224|Proteobacteria,2VUD5@28216|Betaproteobacteria,4AEEX@80864|Comamonadaceae	28216|Betaproteobacteria	U	General secretion pathway protein H	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
PYH2_k127_4646721_13	1276756.AUEX01000016_gene1861	3.062e-66	232.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR7N@28216|Betaproteobacteria,4ADIE@80864|Comamonadaceae	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
PYH2_k127_4646721_17	420662.Mpe_A3127	2.986e-29	125.0	2DP58@1|root,32UKC@2|Bacteria,1N8RA@1224|Proteobacteria,2VW6I@28216|Betaproteobacteria,1KMMH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	general secretion pathway protein	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
PYH2_k127_4646721_3	1265502.KB905948_gene1003	1.092e-196	631.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,4AC6C@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
PYH2_k127_4650889_2	1499967.BAYZ01000076_gene808	6.446e-05	47.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
PYH2_k127_4650889_1	869210.Marky_0418	2.299e-27	118.0	COG1597@1|root,COG1597@2|Bacteria,1WI0N@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Diacylglycerol kinase, catalytic	bmrU	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
PYH2_k127_4650889_0	1223521.BBJX01000007_gene1560	1.314e-235	737.0	COG0439@1|root,COG4770@1|root,COG4799@1|root,COG0439@2|Bacteria,COG4770@2|Bacteria,COG4799@2|Bacteria,1MU4H@1224|Proteobacteria,2VJRB@28216|Betaproteobacteria,4ABDE@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carbamoyl-phosphate synthase L chain, ATP-binding	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
PYH2_k127_4654541_2	153948.NAL212_1557	1.352e-55	203.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,372UK@32003|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
PYH2_k127_4654541_1	864051.BurJ1DRAFT_0884	8.473e-104	341.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,1KJ37@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	response regulator	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
PYH2_k127_4654541_0	864051.BurJ1DRAFT_0883	1.547e-229	723.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,1KJ1E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
PYH2_k127_466884_3	1265502.KB905935_gene3091	2.519e-74	252.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria,4ADK4@80864|Comamonadaceae	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
PYH2_k127_466884_1	864051.BurJ1DRAFT_2480	2.785e-119	389.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,1KKI3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PYH2_k127_466884_6	397945.Aave_2651	5.49e-10	65.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,4A9S4@80864|Comamonadaceae	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
PYH2_k127_466884_0	420662.Mpe_A2530	1.158e-183	589.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,1KJ2P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	lytic transglycosylase	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
PYH2_k127_466884_2	983917.RGE_32980	3.087e-88	295.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,1KJ29@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
PYH2_k127_466884_4	983917.RGE_32990	8.53e-52	185.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,1KM4W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
PYH2_k127_466884_5	420662.Mpe_A2534	6.991e-29	119.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,1KJYI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
PYH2_k127_4670228_0	595537.Varpa_5382	1.938e-162	517.0	COG0451@1|root,COG0451@2|Bacteria,1MU1A@1224|Proteobacteria,2VHGA@28216|Betaproteobacteria,4AASB@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.410	ko:K22025	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
PYH2_k127_4670228_1	279714.FuraDRAFT_3526	1.634e-94	314.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VMN4@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Class II aldolase	fucA	-	4.1.1.104,4.1.2.17	ko:K01628,ko:K22130	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
PYH2_k127_4670228_2	748280.NH8B_1337	1.438e-25	107.0	COG3395@1|root,COG3395@2|Bacteria,1MW4G@1224|Proteobacteria,2VI5S@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM type III effector Hrp-dependent outers	hop	-	2.7.1.217	ko:K21948	-	-	R11706,R11707	-	ko00000,ko01000	-	-	-	DUF1357_C,DUF1537
PYH2_k127_4676604_0	296591.Bpro_2005	0.0	1350.0	COG4666@1|root,COG4666@2|Bacteria,1MUNB@1224|Proteobacteria,2VHUG@28216|Betaproteobacteria,4ABBZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
PYH2_k127_4676604_2	296591.Bpro_2004	2.938e-167	554.0	COG2358@1|root,COG2358@2|Bacteria,1MXW1@1224|Proteobacteria,2VH6G@28216|Betaproteobacteria,4ABRZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
PYH2_k127_4676604_1	1265502.KB905932_gene1799	1.626e-222	704.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VJJ6@28216|Betaproteobacteria,4AAE9@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
PYH2_k127_4676604_13	580332.Slit_1695	3.096e-06	59.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
PYH2_k127_4676604_10	420324.KI912023_gene103	4.322e-60	219.0	COG1177@1|root,COG1177@2|Bacteria,1N854@1224|Proteobacteria,2UF6N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
PYH2_k127_4676604_5	420324.KI912023_gene104	2.225e-96	323.0	COG1176@1|root,COG1176@2|Bacteria,1MW13@1224|Proteobacteria,2TR2S@28211|Alphaproteobacteria,1JSNF@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	MA20_32200	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
PYH2_k127_4676604_3	420324.KI912023_gene105	1.946e-148	483.0	COG0687@1|root,COG0687@2|Bacteria,1MW93@1224|Proteobacteria,2TRJQ@28211|Alphaproteobacteria,1JUAP@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6,SBP_bac_8
PYH2_k127_4676604_4	420324.KI912023_gene101	1.086e-96	332.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,1JQUT@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM ABC transporter related	-	-	3.6.3.25,3.6.3.29	ko:K02017,ko:K02045,ko:K02049,ko:K02052,ko:K11076	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00188,M00189,M00193,M00300	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.2,3.A.1.16,3.A.1.17,3.A.1.6.1,3.A.1.6.3,3.A.1.8	-	-	ABC_tran,TOBE_2
PYH2_k127_4676604_9	420324.KI912023_gene102	2.06e-60	216.0	COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,2TU8G@28211|Alphaproteobacteria,1JU5Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	PFAM peptidase C15 pyroglutamyl peptidase I	MA20_15835	-	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
PYH2_k127_4676604_6	864051.BurJ1DRAFT_3207	1.249e-71	249.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,2VQRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
PYH2_k127_4676604_12	1037409.BJ6T_65110	1.014e-15	83.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_4676604_8	358220.C380_10565	5.101e-70	244.0	COG3915@1|root,COG3915@2|Bacteria,1RDJN@1224|Proteobacteria,2VRG6@28216|Betaproteobacteria,4AEIU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
PYH2_k127_4676604_7	1123392.AQWL01000006_gene707	1.195e-70	251.0	2CB8R@1|root,2Z90U@2|Bacteria,1R4DV@1224|Proteobacteria,2VZZT@28216|Betaproteobacteria,1KSKS@119069|Hydrogenophilales	119069|Hydrogenophilales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4682199_0	420662.Mpe_A0594	2.582e-223	707.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,2VH5R@28216|Betaproteobacteria,1KJUK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
PYH2_k127_4682199_4	864051.BurJ1DRAFT_4152	3.658e-101	335.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,1KJWI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
PYH2_k127_4682199_2	1265502.KB905941_gene2918	8.303e-137	460.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,4AAIA@80864|Comamonadaceae	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6	ubiF	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,SE
PYH2_k127_4682199_3	420662.Mpe_A0589	3.629e-119	389.0	COG3217@1|root,COG3217@2|Bacteria,1MXN2@1224|Proteobacteria,2VI15@28216|Betaproteobacteria,1KIU1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	MOSC N-terminal beta barrel domain	ycbX	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
PYH2_k127_4682199_5	1121104.AQXH01000001_gene2084	3.852e-41	166.0	COG0697@1|root,COG0697@2|Bacteria,4P10M@976|Bacteroidetes	976|Bacteroidetes	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_4682199_1	1265502.KB905941_gene2924	3.687e-138	442.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,4A9MM@80864|Comamonadaceae	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
PYH2_k127_4705961_2	1158292.JPOE01000002_gene1844	2.586e-81	274.0	COG3961@1|root,COG3961@2|Bacteria,1MW2F@1224|Proteobacteria,2VIQN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the TPP enzyme family	ipdC	-	4.1.1.74	ko:K04103	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_4705961_0	1538295.JY96_17190	1.576e-190	601.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,1KMCP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
PYH2_k127_4705961_1	266265.Bxe_A1844	5.93e-134	438.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2VHZ4@28216|Betaproteobacteria,1K1RM@119060|Burkholderiaceae	28216|Betaproteobacteria	S	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
PYH2_k127_4705961_4	420662.Mpe_A3491	1.718e-22	102.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
PYH2_k127_4705961_3	420662.Mpe_A3490	1.956e-46	173.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VT97@28216|Betaproteobacteria,1KM75@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_4723308_2	313612.L8106_08756	1.588e-14	81.0	COG0385@1|root,COG0385@2|Bacteria,1G6ZW@1117|Cyanobacteria,1HFSU@1150|Oscillatoriales	1117|Cyanobacteria	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
PYH2_k127_4723308_1	1454004.AW11_03032	6.541e-67	233.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
PYH2_k127_4723308_0	460265.Mnod_2274	4.011e-100	331.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2TT0G@28211|Alphaproteobacteria,1JR06@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS,Sulfate_transp
PYH2_k127_4731570_0	1121035.AUCH01000005_gene57	4.124e-115	391.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9
PYH2_k127_4737210_0	365044.Pnap_1249	1.73e-150	484.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9PT@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
PYH2_k127_4750976_2	983917.RGE_45890	4.272e-206	645.0	COG2866@1|root,COG2866@2|Bacteria,1R586@1224|Proteobacteria	1224|Proteobacteria	E	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
PYH2_k127_4750976_12	420662.Mpe_A3627	7.875e-15	79.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VRRI@28216|Betaproteobacteria,1KNI7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_4750976_14	267608.RSc1890	0.0001422	45.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VRRI@28216|Betaproteobacteria,1K6Z1@119060|Burkholderiaceae	28216|Betaproteobacteria	C	2Fe-2S -binding domain protein	iorA2	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_4750976_7	420662.Mpe_A3625	1.038e-130	421.0	COG0284@1|root,COG0284@2|Bacteria,1MWH5@1224|Proteobacteria,2VHAB@28216|Betaproteobacteria,1KKBC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
PYH2_k127_4750976_1	864051.BurJ1DRAFT_1733	7.137e-220	694.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,1KJIE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
PYH2_k127_4750976_4	987059.RBXJA2T_04633	3.936e-171	542.0	COG1744@1|root,COG1744@2|Bacteria,1MVU5@1224|Proteobacteria,2VKZI@28216|Betaproteobacteria,1KKIH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	basic membrane	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
PYH2_k127_4750976_8	1370121.AUWS01000021_gene6484	9.572e-89	316.0	COG1011@1|root,COG1011@2|Bacteria,2HHHH@201174|Actinobacteria,2341D@1762|Mycobacteriaceae	201174|Actinobacteria	S	haloacid dehalogenase	dehII	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
PYH2_k127_4750976_3	864051.BurJ1DRAFT_1729	5.654e-205	653.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2WGJY@28216|Betaproteobacteria,1KIYS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
PYH2_k127_4750976_5	983917.RGE_45790	2.02e-163	521.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2VHXA@28216|Betaproteobacteria,1KJKN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PYH2_k127_4750976_10	1163408.UU9_13383	2.334e-50	193.0	COG0563@1|root,COG0563@2|Bacteria,1RK1A@1224|Proteobacteria,1SZQY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4750976_6	864051.BurJ1DRAFT_1727	4.943e-156	496.0	COG1079@1|root,COG1079@2|Bacteria,1NAYV@1224|Proteobacteria,2VJ78@28216|Betaproteobacteria,1KKEK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PYH2_k127_4750976_9	864051.BurJ1DRAFT_3408	3.555e-83	283.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,1KKT5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PYH2_k127_4750976_0	864051.BurJ1DRAFT_1726	9.036e-246	761.0	COG0807@1|root,COG0807@2|Bacteria,1PQ5Y@1224|Proteobacteria,2VJ66@28216|Betaproteobacteria,1KJ1N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	GTP cyclohydrolase N terminal	ribA	-	-	-	-	-	-	-	-	-	-	-	GTP_CH_N,GTP_cyclohydro2
PYH2_k127_4750976_11	864051.BurJ1DRAFT_1725	3.08e-27	116.0	COG0807@1|root,COG0807@2|Bacteria,1MWUM@1224|Proteobacteria,2VJRX@28216|Betaproteobacteria,1KJRK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Protein of unknown function (DUF1688)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1688
PYH2_k127_4755273_4	987059.RBXJA2T_19391	5.995e-25	109.0	COG2823@1|root,COG2823@2|Bacteria,1NIM8@1224|Proteobacteria,2VX5E@28216|Betaproteobacteria,1KNVY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
PYH2_k127_4755273_2	296591.Bpro_4288	1.233e-76	272.0	COG0025@1|root,COG0025@2|Bacteria,1QA7B@1224|Proteobacteria,2VHPR@28216|Betaproteobacteria,4ACQT@80864|Comamonadaceae	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
PYH2_k127_4755273_0	983917.RGE_26440	8.176e-100	341.0	28HHS@1|root,2Z7TD@2|Bacteria,1R7VF@1224|Proteobacteria,2VP2H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3182
PYH2_k127_4755273_1	795666.MW7_2849	4.543e-83	291.0	COG1073@1|root,COG1073@2|Bacteria,1NXZW@1224|Proteobacteria,2VNFH@28216|Betaproteobacteria,1K2U8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4,Peptidase_S9
PYH2_k127_4755273_3	365044.Pnap_2293	2.351e-39	155.0	COG1633@1|root,COG3861@1|root,COG1633@2|Bacteria,COG3861@2|Bacteria,1RGZG@1224|Proteobacteria,2VSVM@28216|Betaproteobacteria,4ABHC@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
PYH2_k127_4756461_3	987059.RBXJA2T_11992	6.735e-74	258.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,1KPCK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	qseC	-	2.7.13.3	ko:K02484,ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
PYH2_k127_4756461_0	987059.RBXJA2T_11997	1.101e-174	561.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,1KIXK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the peptidase S1C family	mucD	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PYH2_k127_4756461_1	864051.BurJ1DRAFT_4531	8.937e-117	383.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VJF9@28216|Betaproteobacteria,1KJZE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
PYH2_k127_4756461_2	987059.RBXJA2T_14201	1.003e-110	369.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria,1KJ7Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PYH2_k127_4756461_4	1538295.JY96_15020	1.742e-48	178.0	COG3271@1|root,COG3271@2|Bacteria,1RA3D@1224|Proteobacteria,2VQ1F@28216|Betaproteobacteria,1KPCT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16,TPR_17
PYH2_k127_4763249_4	864051.BurJ1DRAFT_2430	1.073e-08	57.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VM7N@28216|Betaproteobacteria,1KNHT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR substrate binding domain	gcvA	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_4763249_3	1100721.ALKO01000024_gene487	4.168e-57	211.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VJWK@28216|Betaproteobacteria,4AAJ1@80864|Comamonadaceae	28216|Betaproteobacteria	J	PFAM Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
PYH2_k127_4763249_5	864051.BurJ1DRAFT_4607	6.15e-08	64.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2W9HQ@28216|Betaproteobacteria,1KNK5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit	-	-	-	-	-	-	-	-	-	-	-	-	Amidase
PYH2_k127_4763249_1	395495.Lcho_2991	6.478e-143	471.0	2EFKN@1|root,339CX@2|Bacteria,1N8ST@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4763249_0	395495.Lcho_2991	2.535e-227	720.0	2EFKN@1|root,339CX@2|Bacteria,1N8ST@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4763249_2	614083.AWQR01000007_gene420	1.785e-87	293.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria,4AAN1@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_4805659_8	1121116.KB894774_gene1745	1.209e-06	58.0	COG4974@1|root,COG4974@2|Bacteria,1R1HJ@1224|Proteobacteria,2VP28@28216|Betaproteobacteria,4AD72@80864|Comamonadaceae	28216|Betaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PYH2_k127_4805659_2	395495.Lcho_0664	5.012e-173	548.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,1KJBI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH2_k127_4805659_6	864051.BurJ1DRAFT_1712	1.615e-75	272.0	COG2816@1|root,COG2816@2|Bacteria,1REUJ@1224|Proteobacteria,2VRF4@28216|Betaproteobacteria,1KKP4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nudix N-terminal	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,Nudix_N_2
PYH2_k127_4805659_7	420662.Mpe_A1134	6.653e-35	137.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,1KMF3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	sirA	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
PYH2_k127_4805659_3	983917.RGE_33980	6.029e-167	527.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,1KJ5H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
PYH2_k127_4805659_5	420662.Mpe_A1136	2.113e-118	389.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,2VK9F@28216|Betaproteobacteria,1KJYF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH2_k127_4805659_0	983917.RGE_33960	0.0	1511.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,1KJN2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
PYH2_k127_4805659_4	983917.RGE_33950	8.915e-119	397.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,2VKBJ@28216|Betaproteobacteria,1KN7U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ,PDZ_2,Peptidase_S41
PYH2_k127_4805659_1	983917.RGE_33930	3.219e-197	617.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,2VJMM@28216|Betaproteobacteria,1KIUP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides	guaC	-	1.7.1.7	ko:K00364	ko00230,map00230	-	R01134	RC00457	ko00000,ko00001,ko01000	-	-	-	IMPDH
PYH2_k127_4806016_2	688245.CtCNB1_0016	5.234e-96	325.0	COG1014@1|root,COG1014@2|Bacteria,1MV7Q@1224|Proteobacteria,2VMSN@28216|Betaproteobacteria,4ABYN@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
PYH2_k127_4806016_0	365046.Rta_13910	0.0	1159.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VK1K@28216|Betaproteobacteria,4AASY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	TPP_enzyme_C
PYH2_k127_4806016_3	203124.Tery_2076	1.694e-88	309.0	COG4782@1|root,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
PYH2_k127_4806016_1	1411123.JQNH01000001_gene3911	1.413e-166	554.0	COG3386@1|root,COG3386@2|Bacteria,1MU0C@1224|Proteobacteria,2TSXG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Gluconolactonase	-	-	3.1.1.17	ko:K01053,ko:K14274	ko00030,ko00040,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00040,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02427,R02933,R03751	RC00537,RC00713,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
PYH2_k127_4806016_4	1100720.ALKN01000045_gene318	8.324e-17	79.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,2VI60@28216|Betaproteobacteria,4A9Q2@80864|Comamonadaceae	28216|Betaproteobacteria	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
PYH2_k127_4815640_2	75379.Tint_3070	6.898e-108	355.0	COG0642@1|root,COG2205@2|Bacteria,1MUAK@1224|Proteobacteria,2WGJC@28216|Betaproteobacteria,1KPCI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PYH2_k127_4815640_1	189753.AXAS01000066_gene6109	8.777e-115	374.0	COG1028@1|root,COG1028@2|Bacteria,1MW46@1224|Proteobacteria,2TUTU@28211|Alphaproteobacteria,3JVSJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	KR domain	MA20_15935	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_4815640_0	1380394.JADL01000003_gene5175	6.354e-142	469.0	COG2421@1|root,COG2421@2|Bacteria,1MXKY@1224|Proteobacteria,2TSVA@28211|Alphaproteobacteria,2JR7H@204441|Rhodospirillales	204441|Rhodospirillales	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
PYH2_k127_4815640_6	983917.RGE_38630	3.07e-14	76.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,1KMKS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4815640_7	1541065.JRFE01000024_gene913	3.533e-08	63.0	COG2867@1|root,COG2867@2|Bacteria,1G6MA@1117|Cyanobacteria,3VJPC@52604|Pleurocapsales	1117|Cyanobacteria	I	PFAM Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
PYH2_k127_4815640_3	1123242.JH636437_gene6034	8.944e-89	314.0	COG1052@1|root,COG1052@2|Bacteria	2|Bacteria	CH	NAD binding	-	-	1.1.1.26,1.1.1.399,1.1.1.95	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00020	R00717,R01388,R01513	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH2_k127_4815640_4	1123229.AUBC01000012_gene2696	5.984e-71	249.0	COG3836@1|root,COG3836@2|Bacteria,1QY50@1224|Proteobacteria,2U2PU@28211|Alphaproteobacteria,3K41P@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.20	ko:K01630	ko00053,map00053	-	R02754,R03277	RC00307,RC00435	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
PYH2_k127_4815640_5	1380391.JIAS01000018_gene999	1.886e-67	237.0	2CB42@1|root,2Z7Y3@2|Bacteria,1PK1X@1224|Proteobacteria,2TVBX@28211|Alphaproteobacteria,2JVDF@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4816528_0	365046.Rta_00810	6.497e-161	528.0	COG2079@1|root,COG2079@2|Bacteria,1NECN@1224|Proteobacteria,2VN65@28216|Betaproteobacteria,4A9Q0@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
PYH2_k127_4816528_1	296591.Bpro_1270	1.412e-119	390.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VIGV@28216|Betaproteobacteria,4AB4M@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_4820823_2	94624.Bpet3496	3.855e-109	356.0	COG1012@1|root,COG1012@2|Bacteria,1MW72@1224|Proteobacteria,2VIBR@28216|Betaproteobacteria,3T3DW@506|Alcaligenaceae	28216|Betaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_4820823_1	1265502.KB905949_gene967	7.366e-196	616.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,4AA0A@80864|Comamonadaceae	28216|Betaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
PYH2_k127_4820823_0	1265502.KB905949_gene966	4.215e-233	728.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,4A9UG@80864|Comamonadaceae	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
PYH2_k127_4820823_3	864051.BurJ1DRAFT_4420	6.908e-14	72.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,1KKBH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
PYH2_k127_4823731_0	395495.Lcho_0061	5.955e-131	431.0	COG2143@1|root,COG2143@2|Bacteria,1RB3S@1224|Proteobacteria,2VX2X@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Thioredoxin-like	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	Thioredoxin_2
PYH2_k127_4823731_1	543728.Vapar_3832	7.45e-80	269.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VNJM@28216|Betaproteobacteria,4ACQK@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,PP-binding
PYH2_k127_4825612_20	864051.BurJ1DRAFT_2920	3.394e-32	126.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,1KK2B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	rRNA methyltransferase	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
PYH2_k127_4825612_10	864051.BurJ1DRAFT_2919	1.395e-139	447.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,1KJUU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	ydiA	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
PYH2_k127_4825612_0	1265502.KB905935_gene3031	0.0	1319.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VHQ3@28216|Betaproteobacteria,4AA18@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
PYH2_k127_4825612_21	580332.Slit_2491	3.313e-29	121.0	COG4327@1|root,COG4327@2|Bacteria,1PDE2@1224|Proteobacteria,2VW4R@28216|Betaproteobacteria,44WJQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
PYH2_k127_4825612_4	296591.Bpro_4144	3.565e-286	898.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,4AA9Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP_1	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
PYH2_k127_4825612_23	1123392.AQWL01000002_gene1810	4.815e-16	81.0	2EJDA@1|root,33D4B@2|Bacteria,1NJG2@1224|Proteobacteria,2VXQP@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4825612_12	420662.Mpe_A1523	6.074e-75	257.0	COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VR7H@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
PYH2_k127_4825612_19	1265502.KB905935_gene3028	2.772e-36	139.0	COG4327@1|root,COG4327@2|Bacteria,1NQBY@1224|Proteobacteria,2VV4C@28216|Betaproteobacteria,4AFHH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
PYH2_k127_4825612_2	1265502.KB905935_gene3027	0.0	1123.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,4AA9Z@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	actP_1	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
PYH2_k127_4825612_24	1318628.MARLIPOL_05420	1.892e-11	72.0	2DS4B@1|root,33EG1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4825612_1	1318628.MARLIPOL_05415	0.0	1268.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,46A0J@72275|Alteromonadaceae	1236|Gammaproteobacteria	ET	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
PYH2_k127_4825612_18	1318628.MARLIPOL_05410	1.402e-49	182.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,1SBB6@1236|Gammaproteobacteria,46B2G@72275|Alteromonadaceae	1236|Gammaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PYH2_k127_4825612_8	1318628.MARLIPOL_05405	8.897e-211	679.0	COG2176@1|root,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,1RV0N@1236|Gammaproteobacteria,46AKU@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	PAS_4,PAS_9,RNase_T
PYH2_k127_4825612_11	1265502.KB905948_gene1003	3.531e-92	315.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,4AC6C@80864|Comamonadaceae	28216|Betaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
PYH2_k127_4825612_16	864051.BurJ1DRAFT_2917	1.248e-60	211.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,1KKXS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
PYH2_k127_4825612_22	983917.RGE_27190	1.954e-25	109.0	COG2965@1|root,COG2965@2|Bacteria,1N98W@1224|Proteobacteria,2VVZ4@28216|Betaproteobacteria,1KMH3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Binds single-stranded DNA at the primosome assembly site (PAS)	priB	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SSB
PYH2_k127_4825612_17	864051.BurJ1DRAFT_2915	2.925e-52	186.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,1KM20@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
PYH2_k127_4825612_15	864051.BurJ1DRAFT_2914	8.235e-64	221.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,1KKZX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
PYH2_k127_4825612_6	864051.BurJ1DRAFT_2913	1.015e-228	730.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,1KJ8B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
PYH2_k127_4825612_9	864051.BurJ1DRAFT_2912	2.381e-173	552.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,1KJAR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PYH2_k127_4825612_5	864051.BurJ1DRAFT_2911	5.454e-281	878.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,2VMSK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
PYH2_k127_4825612_7	1538295.JY96_01480	6.128e-212	662.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,1KJVG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
PYH2_k127_4825612_3	983917.RGE_27120	0.0	1103.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,1KKDN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
PYH2_k127_4825612_14	864051.BurJ1DRAFT_2906	3.364e-65	228.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,1KKZ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
PYH2_k127_4825612_13	1265502.KB905930_gene1429	1.505e-72	258.0	COG5281@1|root,COG5281@2|Bacteria,1NZ1M@1224|Proteobacteria,2VS5T@28216|Betaproteobacteria,4AJE7@80864|Comamonadaceae	28216|Betaproteobacteria	D	sister chromatid segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4827882_3	861299.J421_1817	1.6e-06	53.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
PYH2_k127_4827882_0	1042163.BRLA_c023910	3.132e-269	859.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UYA0@1239|Firmicutes,4HA4F@91061|Bacilli,274Q0@186822|Paenibacillaceae	91061|Bacilli	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
PYH2_k127_4827882_1	1042163.BRLA_c023900	2.834e-114	379.0	COG5379@1|root,COG5379@2|Bacteria,1V1UP@1239|Firmicutes,4HX2Z@91061|Bacilli	91061|Bacilli	I	Protein of unknown function (DUF3419)	-	-	-	ko:K13622	ko00564,map00564	-	R09072	RC00021,RC01091	ko00000,ko00001	-	-	-	DUF3419
PYH2_k127_4827882_2	861299.J421_1814	4.676e-73	263.0	COG0170@1|root,COG0170@2|Bacteria	2|Bacteria	I	dolichyl monophosphate biosynthetic process	-	-	2.7.1.182,2.7.7.41	ko:K00981,ko:K18678	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799,R10659	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1,DUF92
PYH2_k127_4830923_1	365044.Pnap_3585	9.548e-72	244.0	COG3108@1|root,COG3108@2|Bacteria,1MWW2@1224|Proteobacteria,2VRCS@28216|Betaproteobacteria,4AE1P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidase M15	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_2
PYH2_k127_4830923_0	365046.Rta_18130	3.206e-154	498.0	COG0042@1|root,COG0042@2|Bacteria,1MUY1@1224|Proteobacteria,2VHCA@28216|Betaproteobacteria,4A9MT@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs	dusA	-	-	ko:K05539	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
PYH2_k127_4830923_2	296591.Bpro_1216	1.047e-19	93.0	COG3631@1|root,COG3631@2|Bacteria,1RI43@1224|Proteobacteria	1224|Proteobacteria	S	Ketosteroid isomerase-related protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4830923_3	497964.CfE428DRAFT_5116	0.0005464	46.0	2942H@1|root,2ZRH9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4834678_2	1286631.X805_31580	1.172e-38	145.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,2VHMT@28216|Betaproteobacteria,1KKI0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Lipocalin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
PYH2_k127_4834678_0	395495.Lcho_1262	5.103e-287	897.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,1KJ7I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PYH2_k127_4834678_1	983917.RGE_00860	3.564e-72	273.0	COG2885@1|root,COG2885@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria,1KKPK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the ompA family	yiaD_1	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA
PYH2_k127_4849496_0	666681.M301_0968	3.937e-242	757.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KMHU@206350|Nitrosomonadales	206350|Nitrosomonadales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
PYH2_k127_4849496_1	1166018.FAES_pFAES01098	5.286e-101	347.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,47KSB@768503|Cytophagia	976|Bacteroidetes	Q	PFAM multicopper oxidase type 3	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
PYH2_k127_4849496_2	358220.C380_05780	3.22e-11	70.0	29WKF@1|root,30I6Z@2|Bacteria,1RFAM@1224|Proteobacteria,2W3J1@28216|Betaproteobacteria,4AI1B@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_485920_0	864051.BurJ1DRAFT_4930	0.0	1569.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,1KJMG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
PYH2_k127_485920_2	420662.Mpe_A0100	7.909e-92	308.0	COG3917@1|root,COG3917@2|Bacteria,1MWB9@1224|Proteobacteria,2VKX5@28216|Betaproteobacteria,1KN0Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
PYH2_k127_485920_3	1157708.KB907464_gene482	6.473e-77	266.0	COG0412@1|root,COG0412@2|Bacteria,1MW88@1224|Proteobacteria,2VQD1@28216|Betaproteobacteria,4ACGY@80864|Comamonadaceae	28216|Betaproteobacteria	Q	dienelactone hydrolase	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
PYH2_k127_485920_1	864051.BurJ1DRAFT_4933	3.679e-127	413.0	COG3618@1|root,COG3618@2|Bacteria,1QWWJ@1224|Proteobacteria,2VMAE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
PYH2_k127_485920_5	864051.BurJ1DRAFT_4936	1.8e-45	171.0	COG5531@1|root,COG5531@2|Bacteria,1N3MD@1224|Proteobacteria,2VSPC@28216|Betaproteobacteria,1KMDW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	B	SWI complex, BAF60b domains	-	-	-	-	-	-	-	-	-	-	-	-	SWIB
PYH2_k127_485920_7	1265502.KB905937_gene2538	5.885e-25	107.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,2VJB9@28216|Betaproteobacteria,4AAWD@80864|Comamonadaceae	28216|Betaproteobacteria	P	membrane protein TerC	ygjT	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
PYH2_k127_485920_4	987059.RBXJA2T_13439	2.853e-46	172.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,1KMF8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM Membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
PYH2_k127_485920_8	864051.BurJ1DRAFT_4938	7.396e-24	104.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,1KKB2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase family M48	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
PYH2_k127_4903038_0	420662.Mpe_A0631	5.067e-207	652.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KJ12@119065|unclassified Burkholderiales	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	rhlE2	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
PYH2_k127_4903038_1	420662.Mpe_A0630	3.294e-104	343.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VIE1@28216|Betaproteobacteria,1KK36@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyl transferase, family 4	wecA	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
PYH2_k127_4903674_2	204773.HEAR1440	4.531e-120	394.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,2VHMU@28216|Betaproteobacteria,4740F@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	DnaJ C terminal domain	cbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
PYH2_k127_4903674_4	398527.Bphyt_6321	6.14e-26	112.0	COG0789@1|root,COG0789@2|Bacteria,1N9MT@1224|Proteobacteria,2VVPZ@28216|Betaproteobacteria,1K9TU@119060|Burkholderiaceae	28216|Betaproteobacteria	K	MerR HTH family regulatory protein	-	-	-	ko:K18997	-	-	-	-	ko00000,ko03036	-	-	-	MerR_2
PYH2_k127_4903674_1	338969.Rfer_2419	7.459e-142	457.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria,4AAJH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
PYH2_k127_4903674_0	1538295.JY96_08700	8.995e-229	717.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,1KJ8G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
PYH2_k127_4903674_6	1123255.JHYS01000020_gene2741	1.142e-06	56.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,4AJVP@80864|Comamonadaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_4903674_3	420662.Mpe_A3775	7.56e-32	136.0	COG3963@1|root,COG3963@2|Bacteria,1N1KB@1224|Proteobacteria,2VX9M@28216|Betaproteobacteria,1KP6D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Phospholipid N-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,RrnaAD
PYH2_k127_4929818_2	1538295.JY96_01725	1.908e-89	296.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,1KJSQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
PYH2_k127_4929818_1	983917.RGE_15010	1.33e-160	511.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,1KIY3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
PYH2_k127_4929818_0	614083.AWQR01000030_gene2802	1.785e-250	775.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,4A9T6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PYH2_k127_4929818_3	987059.RBXJA2T_12382	2.082e-34	133.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,1KMJY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
PYH2_k127_4929818_4	864051.BurJ1DRAFT_3707	2.32e-07	53.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,2VRT2@28216|Betaproteobacteria,1KKZ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
PYH2_k127_4944607_1	395495.Lcho_1692	1.176e-145	472.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,1KJCR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
PYH2_k127_4944607_0	987059.RBXJA2T_07373	2.466e-197	636.0	COG0837@1|root,COG1737@1|root,COG0837@2|Bacteria,COG1737@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,1KK56@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase,HTH_6,SIS
PYH2_k127_4944607_2	987059.RBXJA2T_07368	2.084e-16	85.0	COG0837@1|root,COG0837@2|Bacteria,1MVFI@1224|Proteobacteria,2VH5F@28216|Betaproteobacteria,1KK56@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the bacterial glucokinase family	glk	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucokinase
PYH2_k127_4948037_2	1384054.N790_09130	3.518e-33	130.0	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,1RZKS@1236|Gammaproteobacteria,1XC7A@135614|Xanthomonadales	135614|Xanthomonadales	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_4948037_1	1265502.KB905929_gene2251	3.695e-38	149.0	COG2913@1|root,COG2913@2|Bacteria,1N9H2@1224|Proteobacteria,2VVXE@28216|Betaproteobacteria,4AFFS@80864|Comamonadaceae	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	SmpA_OmlA
PYH2_k127_4948037_0	56780.SYN_01481	3.517e-143	471.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MQZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
PYH2_k127_4951176_0	1265502.KB905929_gene2273	3.757e-243	754.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,4A9QY@80864|Comamonadaceae	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH2_k127_4951176_3	420662.Mpe_A2158	2.077e-88	302.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,1KK51@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
PYH2_k127_4951176_2	420662.Mpe_A2159	1.449e-127	411.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,1KJ1J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
PYH2_k127_4951176_1	864051.BurJ1DRAFT_3941	4.68e-132	433.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,1KJ0A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
PYH2_k127_496451_1	1380394.JADL01000002_gene1228	1.839e-205	648.0	COG5310@1|root,COG5310@2|Bacteria,1MUZB@1224|Proteobacteria,2TRTR@28211|Alphaproteobacteria,2JR46@204441|Rhodospirillales	204441|Rhodospirillales	Q	Homospermidine synthase	hss	-	2.5.1.44	ko:K00808	ko00960,ko01110,map00960,map01110	-	R00018	RC00053	ko00000,ko00001,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
PYH2_k127_496451_2	296591.Bpro_0929	4.008e-66	247.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
PYH2_k127_496451_0	529818.AMSG_11344T0	1.208e-241	759.0	COG0282@1|root,2QSJJ@2759|Eukaryota	2759|Eukaryota	C	Acetate kinase	-	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
PYH2_k127_497096_3	864051.BurJ1DRAFT_1394	7.049e-23	112.0	COG1075@1|root,COG1075@2|Bacteria,1R88U@1224|Proteobacteria,2VPDJ@28216|Betaproteobacteria,1KN12@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PGAP1
PYH2_k127_497096_0	338969.Rfer_2533	1.294e-146	469.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VK4X@28216|Betaproteobacteria,4AE55@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_497096_2	1005048.CFU_4089	2.899e-34	136.0	COG2259@1|root,COG2259@2|Bacteria,1N06A@1224|Proteobacteria,2VU8E@28216|Betaproteobacteria,477WH@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
PYH2_k127_497096_1	1244869.H261_03453	2.497e-47	180.0	COG2267@1|root,COG2267@2|Bacteria,1QUZX@1224|Proteobacteria,2TWE4@28211|Alphaproteobacteria,2JZ48@204441|Rhodospirillales	204441|Rhodospirillales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH2_k127_497096_4	688245.CtCNB1_3368	1.238e-22	111.0	COG1802@1|root,COG1802@2|Bacteria,1RCFJ@1224|Proteobacteria,2W1UT@28216|Betaproteobacteria,4AH7G@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_497096_5	665942.HMPREF1022_02003	9.727e-07	54.0	COG0730@1|root,COG0730@2|Bacteria,1NAFA@1224|Proteobacteria,42Y8A@68525|delta/epsilon subdivisions,2WU4U@28221|Deltaproteobacteria,2MBAN@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
PYH2_k127_4982984_4	1121035.AUCH01000026_gene3357	2.154e-22	98.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,2KWNI@206389|Rhodocyclales	206389|Rhodocyclales	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
PYH2_k127_4982984_0	76114.ebA3841	3.591e-69	239.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,2KW6K@206389|Rhodocyclales	206389|Rhodocyclales	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
PYH2_k127_4982984_1	1247649.D560_1442	1.665e-60	214.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,3T3SI@506|Alcaligenaceae	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
PYH2_k127_4982984_3	1121004.ATVC01000003_gene514	5.865e-41	154.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,2KRHM@206351|Neisseriales	206351|Neisseriales	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
PYH2_k127_4982984_2	1266925.JHVX01000018_gene1811	5.386e-43	157.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,372JB@32003|Nitrosomonadales	28216|Betaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
PYH2_k127_4995234_10	395495.Lcho_2706	7.196e-62	217.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,1KM6B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinate dehydrogenase cytochrome b556 subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
PYH2_k127_4995234_9	395495.Lcho_2705	7.95e-64	220.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,1KKWA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinate dehydrogenase hydrophobic membrane anchor protein	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
PYH2_k127_4995234_2	987059.RBXJA2T_09909	0.0	1069.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,1KJ0V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PYH2_k127_4995234_6	1265502.KB905929_gene2262	1.441e-136	458.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,4AB1W@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
PYH2_k127_4995234_11	1265502.KB905929_gene2263	9.167e-29	118.0	COG2938@1|root,COG2938@2|Bacteria,1N2AS@1224|Proteobacteria,2VVYR@28216|Betaproteobacteria,4AFH3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
PYH2_k127_4995234_4	864051.BurJ1DRAFT_2093	2.397e-268	828.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,1KJII@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PYH2_k127_4995234_7	864051.BurJ1DRAFT_3956	4.277e-103	339.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,2VN1E@28216|Betaproteobacteria,1KJZK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_4995234_0	365046.Rta_18230	0.0	1259.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,4AA6N@80864|Comamonadaceae	28216|Betaproteobacteria	I	Methylmalonyl-CoA mutase large subunit	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
PYH2_k127_4995234_5	420662.Mpe_A1015	8.783e-165	523.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2VIRF@28216|Betaproteobacteria,1KJBP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
PYH2_k127_4995234_3	864051.BurJ1DRAFT_3953	9.568e-311	973.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VIYF@28216|Betaproteobacteria,1KK87@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
PYH2_k127_4995234_1	395495.Lcho_2693	0.0	1105.0	COG4770@1|root,COG4770@2|Bacteria,1P6RE@1224|Proteobacteria,2VH59@28216|Betaproteobacteria,1KJ3N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Biotin carboxylase C-terminal domain	pccA	-	6.4.1.3	ko:K01965	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
PYH2_k127_4995234_8	864051.BurJ1DRAFT_3951	2.014e-85	287.0	COG0346@1|root,COG0346@2|Bacteria,1RA9H@1224|Proteobacteria,2VQ0D@28216|Betaproteobacteria,1KKQ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase_4
PYH2_k127_4995234_12	667632.KB890185_gene478	2.068e-24	104.0	COG3360@1|root,COG3360@2|Bacteria,1PW6C@1224|Proteobacteria,2VXDE@28216|Betaproteobacteria,1KB0W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
PYH2_k127_5006380_7	543728.Vapar_2905	2.024e-94	318.0	COG1802@1|root,COG1802@2|Bacteria,1N7GE@1224|Proteobacteria,2VNZS@28216|Betaproteobacteria,4ABT8@80864|Comamonadaceae	28216|Betaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_5006380_0	595537.Varpa_3160	5.776e-222	702.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VI9Q@28216|Betaproteobacteria,4ADCR@80864|Comamonadaceae	28216|Betaproteobacteria	E	Aminotransferase class-V	sgaA	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
PYH2_k127_5006380_10	743299.Acife_1435	2.1e-35	143.0	COG0558@1|root,COG0558@2|Bacteria,1MZ8B@1224|Proteobacteria,1SAHT@1236|Gammaproteobacteria,2ND8Z@225057|Acidithiobacillales	225057|Acidithiobacillales	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
PYH2_k127_5006380_5	1007105.PT7_1573	5.446e-146	471.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH2_k127_5006380_9	1007105.PT7_1572	4.347e-36	154.0	COG3090@1|root,COG3090@2|Bacteria,1N0N7@1224|Proteobacteria	1224|Proteobacteria	G	COG3090 TRAP-type C4-dicarboxylate transport system small permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH2_k127_5006380_1	1007105.PT7_1571	9.852e-186	599.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH2_k127_5006380_6	1156919.QWC_30223	3.703e-114	373.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,3T393@506|Alcaligenaceae	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_5006380_3	94624.Bpet4355	6.622e-156	502.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VJJD@28216|Betaproteobacteria,3T2PV@506|Alcaligenaceae	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
PYH2_k127_5006380_12	224911.27354820	7.102e-28	125.0	2BJPK@1|root,32E16@2|Bacteria,1NNEC@1224|Proteobacteria,2UVPH@28211|Alphaproteobacteria,3K4NR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5006380_8	1267005.KB911255_gene2616	4.646e-72	257.0	COG3391@1|root,COG3391@2|Bacteria,1RGAJ@1224|Proteobacteria,2U5SB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
PYH2_k127_5006380_4	1157708.KB907453_gene4101	1.13e-147	474.0	COG1250@1|root,COG1250@2|Bacteria,1MVVD@1224|Proteobacteria,2WEBM@28216|Betaproteobacteria,4AJQZ@80864|Comamonadaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
PYH2_k127_5006380_2	595537.Varpa_1641	4.769e-184	583.0	COG0240@1|root,COG0240@2|Bacteria,1MXI9@1224|Proteobacteria,2VW0B@28216|Betaproteobacteria,4AJYR@80864|Comamonadaceae	28216|Betaproteobacteria	C	NAD NADP octopine nopaline dehydrogenase	-	-	1.5.1.28	ko:K04940	-	-	-	-	ko00000,ko01000	-	-	-	ApbA,NAD_Gly3P_dh_N,Octopine_DH
PYH2_k127_5006380_11	1522072.IL54_1686	3.446e-30	125.0	COG0251@1|root,COG0251@2|Bacteria,1N30R@1224|Proteobacteria,2UCQ8@28211|Alphaproteobacteria,2K5V4@204457|Sphingomonadales	204457|Sphingomonadales	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH2_k127_5006380_13	392499.Swit_0497	7.56e-23	103.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2K130@204457|Sphingomonadales	28211|Alphaproteobacteria	E	Threonine dehydratase	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PYH2_k127_5016748_1	1286631.X805_22860	4.661e-74	253.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,1KKXV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
PYH2_k127_5016748_0	864051.BurJ1DRAFT_4938	5.721e-111	368.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,1KKB2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase family M48	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
PYH2_k127_5037472_12	640081.Dsui_0870	1.744e-05	53.0	COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria,2KX7E@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
PYH2_k127_5037472_9	395494.Galf_2212	1.884e-21	98.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,44WIE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
PYH2_k127_5037472_3	864051.BurJ1DRAFT_0139	3.282e-78	267.0	COG2258@1|root,COG2258@2|Bacteria,1RAPM@1224|Proteobacteria,2VQFZ@28216|Betaproteobacteria,1KKJM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
PYH2_k127_5037472_6	864051.BurJ1DRAFT_3790	1.311e-57	212.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,2WEFV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	Lipase_GDSL_2
PYH2_k127_5037472_5	1286631.X805_40860	1.439e-66	231.0	COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,2VR7C@28216|Betaproteobacteria,1KM1Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Lysin motif	ygaU	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
PYH2_k127_5037472_7	1265502.KB905944_gene741	1.743e-47	183.0	COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,2VM18@28216|Betaproteobacteria,4AA9P@80864|Comamonadaceae	28216|Betaproteobacteria	S	Ammonia monooxygenase	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
PYH2_k127_5037472_10	1245471.PCA10_42840	1.171e-13	78.0	COG3180@1|root,COG3180@2|Bacteria,1MUFS@1224|Proteobacteria,1SC5I@1236|Gammaproteobacteria,1YEYP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Pfam:AmoA	-	-	-	ko:K07120	-	-	-	-	ko00000	-	-	-	AbrB
PYH2_k127_5037472_2	864051.BurJ1DRAFT_0120	1.068e-95	319.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,2VIYU@28216|Betaproteobacteria,1KJAU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PYH2_k127_5037472_11	748247.AZKH_0274	7.512e-09	61.0	COG4727@1|root,COG4727@2|Bacteria,1R6TR@1224|Proteobacteria,2VKYF@28216|Betaproteobacteria,2KZ8R@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized protein conserved in bacteria (DUF2145)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2145
PYH2_k127_5037472_1	748247.AZKH_0279	6.024e-114	384.0	COG2159@1|root,COG2159@2|Bacteria,1R7E1@1224|Proteobacteria,2VPY4@28216|Betaproteobacteria,2KVED@206389|Rhodocyclales	206389|Rhodocyclales	S	Amidohydrolase	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
PYH2_k127_5037472_0	420662.Mpe_A3732	8.135e-305	945.0	COG0204@1|root,COG0204@2|Bacteria,1MWDY@1224|Proteobacteria,2VJ4I@28216|Betaproteobacteria,1KK6V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Major facilitator superfamily	aas	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	Acyltransferase,MFS_1
PYH2_k127_5037472_4	864051.BurJ1DRAFT_0115	2.822e-77	264.0	COG1266@1|root,COG1266@2|Bacteria,1RJZQ@1224|Proteobacteria,2VSUQ@28216|Betaproteobacteria,1KNGN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
PYH2_k127_5037472_8	1538295.JY96_05230	8.42e-38	147.0	2DMT2@1|root,32TGY@2|Bacteria,1R3E1@1224|Proteobacteria,2VUA9@28216|Betaproteobacteria,1KMIT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5081468_0	1121861.KB899915_gene1893	1.947e-136	453.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TQQH@28211|Alphaproteobacteria,2JPYV@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
PYH2_k127_5081468_1	1095769.CAHF01000022_gene348	1.096e-110	366.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1MXA1@1224|Proteobacteria,2VNV5@28216|Betaproteobacteria,475N7@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Substrate binding domain of ABC-type glycine betaine transport system	opuBC	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
PYH2_k127_5086333_0	420662.Mpe_A1382	2.865e-288	889.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,1KIZQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
PYH2_k127_5108736_1	1122185.N792_05770	3.346e-44	166.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RP1N@1236|Gammaproteobacteria,1X6M0@135614|Xanthomonadales	135614|Xanthomonadales	S	LemA family	-	-	-	-	-	-	-	-	-	-	-	-	LemA
PYH2_k127_5108736_0	1384054.N790_09030	4.156e-124	418.0	COG4907@1|root,COG4907@2|Bacteria,1MXPY@1224|Proteobacteria,1RQUG@1236|Gammaproteobacteria,1X59Q@135614|Xanthomonadales	135614|Xanthomonadales	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
PYH2_k127_5116180_4	342113.DM82_3038	7.373e-57	213.0	COG1664@1|root,COG1664@2|Bacteria,1MUS9@1224|Proteobacteria	1224|Proteobacteria	M	Type ii and iii secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
PYH2_k127_5116180_2	1223521.BBJX01000014_gene312	3.37e-125	408.0	COG3621@1|root,COG3621@2|Bacteria,1R852@1224|Proteobacteria,2VM84@28216|Betaproteobacteria,4AEPA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
PYH2_k127_5116180_1	864051.BurJ1DRAFT_4017	2.678e-151	504.0	COG0845@1|root,COG0845@2|Bacteria,1PJHF@1224|Proteobacteria,2VIRN@28216|Betaproteobacteria,1KKJ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
PYH2_k127_5116180_0	1276756.AUEX01000006_gene3119	0.0	1122.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,2VKF8@28216|Betaproteobacteria,4ACQA@80864|Comamonadaceae	28216|Betaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_5116180_3	1276756.AUEX01000006_gene3120	1.34e-118	389.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJ7G@28216|Betaproteobacteria,4ABCH@80864|Comamonadaceae	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_5116180_5	543728.Vapar_2815	2.892e-24	107.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQAE@28216|Betaproteobacteria,4AE1K@80864|Comamonadaceae	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_5130632_0	522306.CAP2UW1_3052	4.967e-163	520.0	COG2207@1|root,COG2207@2|Bacteria,1PG77@1224|Proteobacteria,2W9CD@28216|Betaproteobacteria,1KQXQ@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
PYH2_k127_5130632_2	76114.ebA6730	2.809e-128	424.0	2CCCK@1|root,2Z7UH@2|Bacteria,1R3SV@1224|Proteobacteria,2W0ZB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5130632_1	1097668.BYI23_B013350	9.042e-137	441.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2VJM3@28216|Betaproteobacteria,1K5G7@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	Methionine biosynthesis protein MetW	ubiE_1	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
PYH2_k127_5130632_3	269799.Gmet_2981	1.487e-79	274.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,42QRD@68525|delta/epsilon subdivisions,2WMYW@28221|Deltaproteobacteria,43T5G@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
PYH2_k127_5132642_1	864051.BurJ1DRAFT_1515	1.859e-67	242.0	COG1629@1|root,COG4771@2|Bacteria,1QWIP@1224|Proteobacteria,2VKD5@28216|Betaproteobacteria,1KKH8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Outer membrane protein beta-barrel family	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH2_k127_5132642_0	1000565.METUNv1_01336	3.259e-199	629.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,2KUMY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
PYH2_k127_5132642_2	864051.BurJ1DRAFT_3968	2.077e-37	145.0	COG0726@1|root,COG0726@2|Bacteria,1R5QW@1224|Proteobacteria,2W4EB@28216|Betaproteobacteria	28216|Betaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5158779_28	864051.BurJ1DRAFT_4371	1.582e-09	59.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,1KK3Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
PYH2_k127_5158779_25	983917.RGE_42460	6.225e-27	118.0	2E58M@1|root,33011@2|Bacteria,1NFX1@1224|Proteobacteria,2VWUP@28216|Betaproteobacteria,1KMKA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5158779_21	983917.RGE_42470	1.08e-52	187.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,1KM0C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
PYH2_k127_5158779_27	1538295.JY96_07060	1.219e-13	72.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,1KJ82@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
PYH2_k127_5158779_29	1071679.BG57_07070	2.052e-07	55.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,1K08A@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186,ko:K16875	ko00130,ko00365,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R10213,R11225	RC00391,RC00814,RC03086,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
PYH2_k127_5158779_14	420662.Mpe_A0518	1.935e-93	312.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria,1KJ0X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
PYH2_k127_5158779_1	864051.BurJ1DRAFT_4376	3.173e-315	972.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,1KK5E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
PYH2_k127_5158779_13	1265502.KB905938_gene2499	2.595e-105	348.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,4AB18@80864|Comamonadaceae	28216|Betaproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
PYH2_k127_5158779_6	864051.BurJ1DRAFT_4378	8.871e-193	609.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,1KK4B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
PYH2_k127_5158779_8	983917.RGE_42530	4.18e-188	593.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,1KJGU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
PYH2_k127_5158779_24	1538295.JY96_15200	3.03e-38	144.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,1KMAC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
PYH2_k127_5158779_23	1538295.JY96_15195	8.543e-49	175.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,1KM31@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
PYH2_k127_5158779_9	864051.BurJ1DRAFT_4382	1.407e-151	485.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,1KIXF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
PYH2_k127_5158779_30	224911.27350827	0.0004217	42.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5158779_2	864051.BurJ1DRAFT_4384	5.744e-307	947.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KJB3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	TIGRFAM type IV-A pilus assembly ATPase PilB	pilB	-	-	ko:K02454,ko:K02504,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
PYH2_k127_5158779_4	983917.RGE_42620	9.157e-210	657.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,1KJSN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
PYH2_k127_5158779_10	420662.Mpe_A0507	9.086e-137	439.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,1KIZ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
PYH2_k127_5158779_19	983917.RGE_42640	2.333e-66	233.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,1KKZP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
PYH2_k127_5158779_12	1265502.KB905938_gene2488	6.501e-117	380.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,4AAE5@80864|Comamonadaceae	28216|Betaproteobacteria	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
PYH2_k127_5158779_26	983917.RGE_42660	2.49e-15	89.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,1KMRT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
PYH2_k127_5158779_15	395495.Lcho_2406	2.764e-92	306.0	COG0663@1|root,COG0663@2|Bacteria,1MVUI@1224|Proteobacteria,2VH4Y@28216|Betaproteobacteria,1KJ2X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	paaY	-	-	ko:K02617,ko:K08279	-	-	-	-	ko00000	-	-	-	Hexapep
PYH2_k127_5158779_17	1157708.KB907452_gene3752	1.285e-75	263.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2VHE9@28216|Betaproteobacteria,4ACR5@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
PYH2_k127_5158779_20	1123504.JQKD01000013_gene1026	8.674e-64	222.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,2VRC2@28216|Betaproteobacteria,4AEJU@80864|Comamonadaceae	28216|Betaproteobacteria	Q	phenylacetic acid degradation protein PaaD	paaI	GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
PYH2_k127_5158779_3	395495.Lcho_2403	3.809e-242	752.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VI46@28216|Betaproteobacteria,1KJ6S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
PYH2_k127_5158779_5	1123504.JQKD01000013_gene1024	2.718e-194	608.0	COG3396@1|root,COG3396@2|Bacteria,1MVQ7@1224|Proteobacteria,2VHQZ@28216|Betaproteobacteria,4A9YX@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM phenylacetic acid catabolic family protein	paaA	-	1.14.13.149	ko:K02609	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
PYH2_k127_5158779_22	1158292.JPOE01000002_gene3133	1.121e-51	183.0	COG3460@1|root,COG3460@2|Bacteria,1RHM5@1224|Proteobacteria,2VSR2@28216|Betaproteobacteria,1KM6E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	TIGRFAM phenylacetate-CoA oxygenase, PaaH subunit	paaB	-	-	ko:K02610	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	PaaB
PYH2_k127_5158779_11	398578.Daci_0812	6.855e-118	383.0	COG3396@1|root,COG3396@2|Bacteria,1MVYQ@1224|Proteobacteria,2VJ03@28216|Betaproteobacteria,4AAF2@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM phenylacetic acid catabolic family protein	paaC	-	1.14.13.149	ko:K02611	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001,ko01000	-	-	-	PaaA_PaaC
PYH2_k127_5158779_18	1123504.JQKD01000013_gene1021	1.227e-69	240.0	COG2151@1|root,COG2151@2|Bacteria,1RF3S@1224|Proteobacteria,2VQI0@28216|Betaproteobacteria,4AE5G@80864|Comamonadaceae	28216|Betaproteobacteria	L	TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit	paaD	-	-	ko:K02612	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FeS_assembly_P
PYH2_k127_5158779_7	395495.Lcho_3569	9.108e-192	606.0	COG1018@1|root,COG1018@2|Bacteria,1MY2Q@1224|Proteobacteria,2VKK1@28216|Betaproteobacteria,1KJ3K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	TIGRFAM phenylacetate-CoA oxygenase reductase, PaaK subunit	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
PYH2_k127_5158779_16	395495.Lcho_2402	5.605e-79	269.0	COG1309@1|root,COG1309@2|Bacteria,1QYD4@1224|Proteobacteria,2VMMD@28216|Betaproteobacteria,1KKNT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	paaR	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
PYH2_k127_5158779_0	543728.Vapar_1226	0.0	1074.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,2VH7K@28216|Betaproteobacteria,4AGME@80864|Comamonadaceae	28216|Betaproteobacteria	CI	MaoC like domain	paaN	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,MaoC_dehydratas
PYH2_k127_5159558_0	864051.BurJ1DRAFT_2800	8.499e-222	702.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,1KJX0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
PYH2_k127_517178_0	1504672.669787431	2.783e-208	654.0	COG1012@1|root,COG1012@2|Bacteria,1QUBI@1224|Proteobacteria,2VM1C@28216|Betaproteobacteria,4ABP0@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dehydrogenase	-	-	1.2.1.81	ko:K15515	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
PYH2_k127_517178_1	595537.Varpa_4410	5.269e-133	438.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VNJM@28216|Betaproteobacteria,4ACQK@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,PP-binding
PYH2_k127_5193188_8	1218075.BAYA01000052_gene6851	4.845e-39	148.0	COG2963@1|root,COG2963@2|Bacteria,1N06K@1224|Proteobacteria,2VUF3@28216|Betaproteobacteria,1K8JG@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
PYH2_k127_5193188_1	224911.27349795	4.561e-124	403.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,2TRX0@28211|Alphaproteobacteria,3JW35@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
PYH2_k127_5193188_15	5341.XP_007331603.1	0.0001609	47.0	2CXRU@1|root,2RZAA@2759|Eukaryota,3AKC6@33154|Opisthokonta,3PDD5@4751|Fungi,3V7F4@5204|Basidiomycota,22FI0@155619|Agaricomycetes,3WA42@5338|Agaricales	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5193188_14	89187.ISM_09556	2.698e-10	65.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,46S10@74030|Roseovarius	28211|Alphaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	csbD	-	-	-	-	-	-	-	-	-	-	-	CsbD
PYH2_k127_5193188_13	983917.RGE_10150	1.307e-11	72.0	COG2823@1|root,COG2823@2|Bacteria	2|Bacteria	S	hyperosmotic response	-	-	-	-	-	-	-	-	-	-	-	-	BON
PYH2_k127_5193188_5	267608.RSc0292	1.43e-68	239.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VME6@28216|Betaproteobacteria,1K3H4@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH2_k127_5193188_12	1267211.KI669560_gene2237	1.934e-12	75.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	GerE,Response_reg,TauD
PYH2_k127_5193188_6	1235457.C404_19695	1.544e-58	221.0	COG4585@1|root,COG5278@1|root,COG4585@2|Bacteria,COG5278@2|Bacteria,1MWPN@1224|Proteobacteria,2VJR2@28216|Betaproteobacteria,1K4ZR@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Histidine kinase	vsrA	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	CHASE3,HATPase_c,HisKA_3
PYH2_k127_5193188_10	1163398.AJJP01000036_gene414	5.237e-30	128.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,1S2G2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Bacterioferritin	IV02_12050	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
PYH2_k127_5193188_9	1265502.KB905933_gene1997	1.31e-33	133.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VUCR@28216|Betaproteobacteria,4AJJA@80864|Comamonadaceae	28216|Betaproteobacteria	S	BON domain	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
PYH2_k127_5193188_2	864051.BurJ1DRAFT_3133	9.04e-113	374.0	COG0657@1|root,COG0657@2|Bacteria,1MV3J@1224|Proteobacteria,2VNRV@28216|Betaproteobacteria,1KKZ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxylesterase family	-	-	3.5.1.9	ko:K01432	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_3,COesterase
PYH2_k127_5193188_4	864051.BurJ1DRAFT_3132	4.734e-82	274.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,2VQ31@28216|Betaproteobacteria,1KKQS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH2_k127_5193188_0	864051.BurJ1DRAFT_3131	1.239e-263	815.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,2VJ6T@28216|Betaproteobacteria,1KJDG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3501
PYH2_k127_5193188_3	395495.Lcho_2672	7.62e-84	299.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,2VQUX@28216|Betaproteobacteria,1KJPT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
PYH2_k127_5193188_11	289376.THEYE_A0161	2.562e-18	94.0	COG1592@1|root,COG1592@2|Bacteria,3J0RY@40117|Nitrospirae	40117|Nitrospirae	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH2_k127_5193188_7	864051.BurJ1DRAFT_2881	9.973e-51	186.0	28JVP@1|root,2Z9KK@2|Bacteria,1R4DG@1224|Proteobacteria,2VPKF@28216|Betaproteobacteria,1KKJP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5202263_1	420324.KI911952_gene3297	3.696e-110	366.0	COG0715@1|root,COG0715@2|Bacteria,1MW0S@1224|Proteobacteria,2VFHT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_2
PYH2_k127_5202263_0	1353531.AZNX01000032_gene5905	2.892e-161	543.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,4BM4C@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1
PYH2_k127_5240649_3	1163617.SCD_n00973	1.671e-37	157.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
PYH2_k127_5240649_0	1123487.KB892863_gene1982	1.294e-106	378.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5240649_1	864051.BurJ1DRAFT_2541	1.746e-69	254.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,1KKAY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Cytochrome c-type biogenesis protein	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
PYH2_k127_5240649_6	292.DM42_1564	2.208e-14	81.0	2E5QB@1|root,330EW@2|Bacteria,1N890@1224|Proteobacteria,2VVXS@28216|Betaproteobacteria,1K8E0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2844
PYH2_k127_5240649_2	1169143.KB911034_gene1037	1.659e-67	249.0	28I2U@1|root,2Z86S@2|Bacteria,1P33F@1224|Proteobacteria,2VP36@28216|Betaproteobacteria,1K5DT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3443)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3443
PYH2_k127_5240649_5	926550.CLDAP_07830	1.189e-17	98.0	COG4447@1|root,COG4447@2|Bacteria,2G66V@200795|Chloroflexi	200795|Chloroflexi	G	glycosyl hydrolase, BNR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
PYH2_k127_5240649_4	159087.Daro_2711	2.652e-30	124.0	COG0810@1|root,COG1193@1|root,COG3064@1|root,COG0810@2|Bacteria,COG1193@2|Bacteria,COG3064@2|Bacteria,1REKC@1224|Proteobacteria,2VRYT@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TonB C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_2
PYH2_k127_5271399_3	1504672.669784578	5.27e-72	247.0	COG0715@1|root,COG0715@2|Bacteria,1NUUC@1224|Proteobacteria,2VJ53@28216|Betaproteobacteria,4ABAQ@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
PYH2_k127_5271399_0	1504672.669784579	4.414e-135	444.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2VMYS@28216|Betaproteobacteria,4AC3X@80864|Comamonadaceae	28216|Betaproteobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PYH2_k127_5271399_1	1504672.669784580	1.628e-119	389.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2VN22@28216|Betaproteobacteria,4ADCK@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PYH2_k127_5271399_2	1504672.669784581	6.505e-111	363.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2WEZF@28216|Betaproteobacteria,4ADME@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PYH2_k127_5277505_6	395495.Lcho_1715	9.197e-59	212.0	COG1752@1|root,COG1752@2|Bacteria,1NRDT@1224|Proteobacteria,2W0SN@28216|Betaproteobacteria,1KNFT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
PYH2_k127_5277505_3	864051.BurJ1DRAFT_0304	2.235e-113	369.0	COG2872@1|root,COG2872@2|Bacteria,1MY0P@1224|Proteobacteria,2VMEB@28216|Betaproteobacteria,1KNEM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	related to alanyl-tRNA synthetase HxxxH domain	alaS_2	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
PYH2_k127_5277505_7	395495.Lcho_3537	1.718e-49	181.0	COG3909@1|root,COG3909@2|Bacteria,1N1E5@1224|Proteobacteria,2VSGD@28216|Betaproteobacteria,1KM1U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM Cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_2
PYH2_k127_5277505_4	864051.BurJ1DRAFT_0306	8.329e-84	284.0	COG3658@1|root,COG3658@2|Bacteria,1RIG7@1224|Proteobacteria,2VQQ0@28216|Betaproteobacteria,1KKNF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
PYH2_k127_5277505_5	420662.Mpe_A0188	4.429e-71	246.0	COG0454@1|root,COG0456@2|Bacteria,1PNX8@1224|Proteobacteria,2VR63@28216|Betaproteobacteria,1KKZ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PYH2_k127_5277505_2	864051.BurJ1DRAFT_0308	5.801e-115	379.0	COG3836@1|root,COG3836@2|Bacteria,1MUSG@1224|Proteobacteria,2VK64@28216|Betaproteobacteria,1KN9V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.2.20	ko:K01630	ko00053,map00053	-	R02754,R03277	RC00307,RC00435	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
PYH2_k127_5277505_1	395495.Lcho_3534	2.968e-122	411.0	COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,2VMAD@28216|Betaproteobacteria,1KJBD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	SMP-30 Gluconolaconase	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
PYH2_k127_5277505_0	983917.RGE_02320	1.114e-198	629.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,1KJK1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
PYH2_k127_5279862_3	698761.RTCIAT899_CH05850	3.649e-15	79.0	COG2114@1|root,COG2888@1|root,COG3899@1|root,COG2114@2|Bacteria,COG2888@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_16,DZR,Guanylate_cyc,TPR_12
PYH2_k127_5279862_1	522306.CAP2UW1_1845	7.201e-56	204.0	COG5010@1|root,COG5010@2|Bacteria,1R0QI@1224|Proteobacteria,2VX62@28216|Betaproteobacteria,1KR08@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	U	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5279862_4	864051.BurJ1DRAFT_3808	2.399e-06	59.0	2EGJB@1|root,33ABH@2|Bacteria,1NI1G@1224|Proteobacteria,2VXT5@28216|Betaproteobacteria,1KMR1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5279862_0	420324.KI912020_gene7416	3.406e-83	283.0	28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2TU05@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	MA20_08580	-	-	-	-	-	-	-	-	-	-	-	Endostatin
PYH2_k127_5279862_2	864051.BurJ1DRAFT_3807	3.68e-22	102.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,1KK83@119065|unclassified Burkholderiales	28216|Betaproteobacteria	JKL	Belongs to the DEAD box helicase family	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
PYH2_k127_528811_18	987059.RBXJA2T_19216	1.128e-37	153.0	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,1KM76@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
PYH2_k127_528811_19	983917.RGE_28090	1.337e-30	127.0	2E95F@1|root,333E6@2|Bacteria,1N8N7@1224|Proteobacteria,2VWX5@28216|Betaproteobacteria,1KMN7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3619)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3619
PYH2_k127_528811_15	864051.BurJ1DRAFT_3006	6.256e-94	311.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,1KKGY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	RNA polymerase sigma factor	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PYH2_k127_528811_1	864051.BurJ1DRAFT_3005	0.0	1074.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,1KKDF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	acetolactate synthase	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_528811_16	864051.BurJ1DRAFT_3004	4.425e-91	302.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,1KJVB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	synthase small subunit	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
PYH2_k127_528811_5	983917.RGE_28050	1.078e-195	613.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,1KIUF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
PYH2_k127_528811_12	1265502.KB905935_gene3130	9.497e-108	354.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria,4AH53@80864|Comamonadaceae	28216|Betaproteobacteria	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
PYH2_k127_528811_7	420662.Mpe_A2102	3.473e-141	452.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,1KJ76@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
PYH2_k127_528811_2	1265502.KB905935_gene3128	1.536e-287	890.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,4AAW6@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
PYH2_k127_528811_11	420662.Mpe_A2100	5.811e-124	406.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,1KJDZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
PYH2_k127_528811_10	983917.RGE_28010	1.109e-127	416.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,2VHB6@28216|Betaproteobacteria,1KIV2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	yiaJ	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
PYH2_k127_528811_8	864051.BurJ1DRAFT_2997	5.325e-135	448.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,1KJUT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Flavin containing amine oxidoreductase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
PYH2_k127_528811_6	864051.BurJ1DRAFT_2996	6.782e-145	464.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,1KIZ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	PFAM Squalene phytoene synthase	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
PYH2_k127_528811_14	1223521.BBJX01000009_gene1173	4.57e-106	352.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,4AA62@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Squalene phytoene synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
PYH2_k127_528811_9	420662.Mpe_A1289	4.842e-131	429.0	COG0845@1|root,COG0845@2|Bacteria,1NJDF@1224|Proteobacteria,2VIS6@28216|Betaproteobacteria,1KK79@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PYH2_k127_528811_0	864051.BurJ1DRAFT_2993	0.0	1654.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHZQ@28216|Betaproteobacteria,1KIUR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
PYH2_k127_528811_20	1080067.BAZH01000008_gene77	4.098e-05	46.0	2AYT6@1|root,31QYG@2|Bacteria,1QNH4@1224|Proteobacteria,1TM2S@1236|Gammaproteobacteria,3WZPT@544|Citrobacter	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_528811_4	983917.RGE_27950	1.42e-209	659.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,1KJCI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
PYH2_k127_528811_13	358220.C380_16070	8.64e-107	351.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,4AA4U@80864|Comamonadaceae	28216|Betaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
PYH2_k127_528811_3	864051.BurJ1DRAFT_2989	5.293e-248	770.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,1KJ1K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
PYH2_k127_528811_17	395495.Lcho_2542	1.164e-74	252.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,1KK9N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
PYH2_k127_5288788_0	1288494.EBAPG3_23620	0.0	1130.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VNZD@28216|Betaproteobacteria,371WU@32003|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
PYH2_k127_5288788_4	1123393.KB891326_gene68	6.163e-53	192.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,1KSJT@119069|Hydrogenophilales	119069|Hydrogenophilales	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5288788_6	380394.Lferr_0210	6.505e-47	172.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,1T9P7@1236|Gammaproteobacteria,2NDUI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
PYH2_k127_5288788_5	913325.N799_00910	4.207e-51	188.0	COG0526@1|root,COG0526@2|Bacteria,1QU2B@1224|Proteobacteria,1T1N1@1236|Gammaproteobacteria,1XD4R@135614|Xanthomonadales	135614|Xanthomonadales	O	Thioredoxin	-	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
PYH2_k127_5288788_3	1158292.JPOE01000005_gene217	5.319e-149	483.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VSBW@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
PYH2_k127_5288788_2	1157708.KB907462_gene884	1.168e-167	538.0	COG0277@1|root,COG0277@2|Bacteria,1N4UQ@1224|Proteobacteria,2W1U4@28216|Betaproteobacteria,4AHE1@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
PYH2_k127_5288788_1	1532558.JL39_10490	2.348e-270	842.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2TRII@28211|Alphaproteobacteria,4BID3@82115|Rhizobiaceae	28211|Alphaproteobacteria	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_5288788_7	1209072.ALBT01000012_gene3407	1.479e-14	78.0	COG4832@1|root,COG4832@2|Bacteria,1RBGY@1224|Proteobacteria,1SAGB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
PYH2_k127_5288788_8	1120956.JHZK01000014_gene1736	7.293e-10	61.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2TRW0@28211|Alphaproteobacteria,1JPV1@119043|Rhodobiaceae	28211|Alphaproteobacteria	C	Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
PYH2_k127_529043_1	1286631.X805_30830	5.458e-49	178.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VQN2@28216|Betaproteobacteria,1KKP7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
PYH2_k127_529043_0	420662.Mpe_A2774	0.0	1308.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,2VJ68@28216|Betaproteobacteria,1KJSB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	aminopeptidase N	pepN	-	3.4.11.2	ko:K01256	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,Peptidase_M1
PYH2_k127_5324248_4	864051.BurJ1DRAFT_2879	4.689e-25	107.0	COG1977@1|root,COG1977@2|Bacteria,1N6RG@1224|Proteobacteria,2VVVJ@28216|Betaproteobacteria,1KMQE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
PYH2_k127_5324248_0	983917.RGE_34300	5.368e-151	487.0	COG4447@1|root,COG4447@2|Bacteria,1ND1J@1224|Proteobacteria,2VMA5@28216|Betaproteobacteria,1KK27@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5324248_2	864051.BurJ1DRAFT_2877	1.691e-62	221.0	2AIHJ@1|root,318ZE@2|Bacteria,1Q18Q@1224|Proteobacteria,2W6AT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5324248_1	887062.HGR_15819	3.073e-64	224.0	COG1246@1|root,COG1846@1|root,COG1246@2|Bacteria,COG1846@2|Bacteria,1MWIC@1224|Proteobacteria,2VI7E@28216|Betaproteobacteria,4ABT5@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, MarR family with acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,MarR_2
PYH2_k127_5324248_3	983917.RGE_34260	3.168e-51	197.0	COG4544@1|root,COG4544@2|Bacteria,1MZQU@1224|Proteobacteria,2VUGI@28216|Betaproteobacteria,1KKX6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	-	-	ko:K13053,ko:K14160	-	-	-	-	ko00000,ko03036,ko03400	-	-	-	SulA
PYH2_k127_5324569_0	983917.RGE_09290	1.752e-286	893.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,1KKBE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ABC transporter	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PYH2_k127_5324569_3	987059.RBXJA2T_15733	7.966e-59	209.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,1KKXD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Thioesterase superfamily	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
PYH2_k127_5324569_1	1003200.AXXA_04468	1.413e-118	385.0	COG1028@1|root,COG1028@2|Bacteria,1PP5H@1224|Proteobacteria,2VJ4Y@28216|Betaproteobacteria,3T2MY@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH2_k127_5324569_2	420662.Mpe_A0143	1.239e-81	282.0	COG0744@1|root,COG0744@2|Bacteria,1NP1W@1224|Proteobacteria,2VKQK@28216|Betaproteobacteria	28216|Betaproteobacteria	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
PYH2_k127_5326501_3	1380394.JADL01000001_gene2373	7.683e-136	439.0	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2TTJ6@28211|Alphaproteobacteria,2JWWP@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC-type spermidine putrescine transport system, permease component I	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
PYH2_k127_5326501_4	1380394.JADL01000001_gene2374	4.714e-121	396.0	COG1177@1|root,COG1177@2|Bacteria,1MUQD@1224|Proteobacteria,2U1YB@28211|Alphaproteobacteria,2JWQU@204441|Rhodospirillales	204441|Rhodospirillales	E	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PYH2_k127_5326501_5	886293.Sinac_4401	9.066e-53	194.0	COG3871@1|root,COG3871@2|Bacteria,2J33T@203682|Planctomycetes	203682|Planctomycetes	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
PYH2_k127_5326501_6	1380390.JIAT01000003_gene5418	9.376e-06	56.0	COG0398@1|root,COG0398@2|Bacteria,2HP5Q@201174|Actinobacteria,4CQHS@84995|Rubrobacteria	84995|Rubrobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
PYH2_k127_5326501_2	296591.Bpro_3531	1.461e-136	443.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VIVP@28216|Betaproteobacteria,4AA44@80864|Comamonadaceae	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH2_k127_5326501_1	395495.Lcho_2217	3.65e-175	579.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,1KKFD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	polyphosphate kinase	ppk2	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
PYH2_k127_5326501_0	1265502.KB905932_gene1951	9.112e-233	730.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,4A9S8@80864|Comamonadaceae	28216|Betaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
PYH2_k127_5329693_3	420662.Mpe_A3064	7.249e-122	400.0	COG1256@1|root,COG1256@2|Bacteria,1MV2M@1224|Proteobacteria,2VH02@28216|Betaproteobacteria,1KJU1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	flagellar hook-associated protein	flgK	-	-	ko:K02396	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PYH2_k127_5329693_5	987059.RBXJA2T_04563	1.546e-84	300.0	COG1705@1|root,COG3951@1|root,COG1705@2|Bacteria,COG3951@2|Bacteria,1MX2W@1224|Proteobacteria,2VH35@28216|Betaproteobacteria,1KK43@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MNOU	TIGRFAM flagellar rod assembly protein muramidase FlgJ	flgJ	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Rod-binding
PYH2_k127_5329693_1	864051.BurJ1DRAFT_3985	9.636e-160	512.0	COG1706@1|root,COG1706@2|Bacteria,1MVKW@1224|Proteobacteria,2VJAZ@28216|Betaproteobacteria,1KIXV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgI	-	-	ko:K02394	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgI
PYH2_k127_5329693_6	420662.Mpe_A3067	1.001e-82	282.0	COG2063@1|root,COG2063@2|Bacteria,1RDEY@1224|Proteobacteria,2VRIC@28216|Betaproteobacteria,1KJYH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation	flgH	-	-	ko:K02393	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgH
PYH2_k127_5329693_2	864051.BurJ1DRAFT_3987	2.457e-131	423.0	COG4786@1|root,COG4786@2|Bacteria,1MVMA@1224|Proteobacteria,2VH7A@28216|Betaproteobacteria,1KJ3E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	flagellar basal-body rod protein	flgG	-	-	ko:K02392	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PYH2_k127_5329693_4	864051.BurJ1DRAFT_4084	9.542e-108	353.0	COG4787@1|root,COG4787@2|Bacteria,1NZWQ@1224|Proteobacteria,2VISC@28216|Betaproteobacteria,1KIXM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar basal-body rod protein FlgF	flgF	-	-	ko:K02391	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PYH2_k127_5329693_0	420662.Mpe_A3070	5.927e-193	609.0	COG1749@1|root,COG1749@2|Bacteria,1MU5J@1224|Proteobacteria,2VIV1@28216|Betaproteobacteria,1KKBK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar hook protein FlgE	flgE	-	-	ko:K02390	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlaE,Flg_bb_rod,Flg_bbr_C
PYH2_k127_5329693_9	983917.RGE_17220	6.998e-57	205.0	COG1843@1|root,COG1843@2|Bacteria,1MXCG@1224|Proteobacteria,2VSF6@28216|Betaproteobacteria,1KKSQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Required for flagellar hook formation. May act as a scaffolding protein	flgD	-	-	ko:K02389	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FLgD_tudor,FlgD,FlgD_ig
PYH2_k127_5329693_7	395495.Lcho_2733	4.521e-63	223.0	COG1558@1|root,COG1558@2|Bacteria,1RHI3@1224|Proteobacteria,2VSK1@28216|Betaproteobacteria,1KKVG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Belongs to the flagella basal body rod proteins family	flgC	-	-	ko:K02388	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod,Flg_bbr_C
PYH2_k127_5329693_10	420662.Mpe_A3073	1.414e-47	176.0	COG1815@1|root,COG1815@2|Bacteria,1MZ8P@1224|Proteobacteria,2VUJ4@28216|Betaproteobacteria,1KM2E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body	flgB	-	-	ko:K02387	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flg_bb_rod
PYH2_k127_5329693_8	420662.Mpe_A3074	3.588e-59	213.0	COG1261@1|root,COG1261@2|Bacteria,1N1SA@1224|Proteobacteria,2VR6V@28216|Betaproteobacteria,1KKTA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly	flgA	-	-	ko:K02386	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	ChapFlgA
PYH2_k127_5329693_13	983917.RGE_17180	3.125e-13	73.0	COG2747@1|root,COG2747@2|Bacteria,1Q0RZ@1224|Proteobacteria,2W8DZ@28216|Betaproteobacteria,1KMRK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	anti-sigma-28 factor	flgM	-	-	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlgM
PYH2_k127_5329693_11	987059.RBXJA2T_18183	4.903e-25	109.0	2E8WI@1|root,3336R@2|Bacteria,1NAVP@1224|Proteobacteria,2VWQJ@28216|Betaproteobacteria,1KMKP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5329693_12	987059.RBXJA2T_11428	1.544e-16	81.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07089,ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
PYH2_k127_5330350_5	420662.Mpe_A1948	3.855e-79	278.0	COG3170@1|root,COG3170@2|Bacteria,1R5KB@1224|Proteobacteria,2VMU6@28216|Betaproteobacteria,1KJDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5330350_1	983917.RGE_29190	2.46e-192	608.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VJD8@28216|Betaproteobacteria,1KJK5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM Aminotransferase class I and II	ybdL	-	2.6.1.88	ko:K14287	-	-	R08618	RC00006,RC00025	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH2_k127_5330350_2	1265502.KB905930_gene1510	2.106e-167	530.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,4A9K9@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	cysB	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_5330350_6	987059.RBXJA2T_03773	2.566e-37	145.0	COG2138@1|root,COG2138@2|Bacteria,1N00J@1224|Proteobacteria,2VTXE@28216|Betaproteobacteria,1KMFU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	CbiX	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
PYH2_k127_5330350_4	864051.BurJ1DRAFT_2714	1.869e-144	474.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria,1KJB9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Permease, YjgP YjgQ	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
PYH2_k127_5330350_3	864051.BurJ1DRAFT_2713	1.785e-159	509.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,1KJUE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Permease, YjgP YjgQ	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
PYH2_k127_5330350_0	420662.Mpe_A1942	1.212e-196	625.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,1KJV6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
PYH2_k127_5330350_7	338969.Rfer_2117	0.0002795	52.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria,4AEZE@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase III, chi subunit	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
PYH2_k127_5335667_3	391735.Veis_1910	1.501e-31	124.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VJNE@28216|Betaproteobacteria,4ACWM@80864|Comamonadaceae	28216|Betaproteobacteria	C	Homoaconitate hydratase family protein	leuC1	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
PYH2_k127_5335667_2	365046.Rta_18450	9.089e-67	236.0	COG0066@1|root,COG0066@2|Bacteria,1RBRQ@1224|Proteobacteria,2VQ2Z@28216|Betaproteobacteria,4ADUE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the LeuD family	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
PYH2_k127_5335667_0	365046.Rta_18440	1.205e-273	858.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2VJZV@28216|Betaproteobacteria,4ABSY@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM amidohydrolase	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
PYH2_k127_5335667_1	762376.AXYL_02698	3.041e-137	447.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2VINH@28216|Betaproteobacteria,3T557@506|Alcaligenaceae	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
PYH2_k127_5344530_12	358220.C380_06845	4.79e-08	60.0	29Z5J@1|root,30M3A@2|Bacteria,1RDK0@1224|Proteobacteria,2VS68@28216|Betaproteobacteria,4AE5V@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5344530_1	420662.Mpe_A1142	0.0	1250.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,1KJ39@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PYH2_k127_5344530_3	232348.ADXL01000058_gene2401	2.049e-159	529.0	COG0114@1|root,COG0114@2|Bacteria,1G0AD@1117|Cyanobacteria,1GYTD@1129|Synechococcus	1117|Cyanobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
PYH2_k127_5344530_9	987059.RBXJA2T_09332	2.167e-58	218.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria,1KMA0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5344530_4	1265502.KB905975_gene598	7.884e-147	470.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,4AB4K@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
PYH2_k127_5344530_11	395495.Lcho_1061	2.45e-17	85.0	2EC30@1|root,3361Z@2|Bacteria,1NB2T@1224|Proteobacteria,2VW1B@28216|Betaproteobacteria,1KMSJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5344530_0	864051.BurJ1DRAFT_3753	0.0	1394.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,1KJS6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
PYH2_k127_5344530_6	864051.BurJ1DRAFT_4817	5.697e-112	367.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria,1KK9F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
PYH2_k127_5344530_8	987059.RBXJA2T_00560	1.079e-64	224.0	COG0589@1|root,COG0589@2|Bacteria,1MZ3K@1224|Proteobacteria,2VSW6@28216|Betaproteobacteria,1KKTH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_5344530_7	1265502.KB905933_gene2047	1.375e-100	336.0	COG2897@1|root,COG2897@2|Bacteria,1MW4B@1224|Proteobacteria,2VHAX@28216|Betaproteobacteria,4AAE1@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM Rhodanese domain protein	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
PYH2_k127_5344530_2	420662.Mpe_A2634	1.065e-191	604.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,1KJBT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rieske 2Fe-2S	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
PYH2_k127_5344530_10	395495.Lcho_3371	9.336e-24	106.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,1KMJ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
PYH2_k127_5344530_5	864051.BurJ1DRAFT_4824	7.237e-118	387.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,1KJQ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
PYH2_k127_5372088_1	1265502.KB905956_gene161	1.855e-61	215.0	COG1522@1|root,COG1522@2|Bacteria,1RD38@1224|Proteobacteria,2VRBA@28216|Betaproteobacteria,4ADWA@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
PYH2_k127_5372088_0	1265502.KB905932_gene1941	2.968e-189	601.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria,4AADM@80864|Comamonadaceae	28216|Betaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
PYH2_k127_5372088_2	420662.Mpe_A3243	7.447e-48	173.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,1KJG0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PYH2_k127_5383_1	1458357.BG58_10210	1.216e-67	233.0	COG2863@1|root,COG2863@2|Bacteria,1N7W9@1224|Proteobacteria,2W0BP@28216|Betaproteobacteria,1K42R@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
PYH2_k127_5383_0	1538295.JY96_03010	4.508e-160	512.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria,1KJQ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	mechanosensitive ion channel	aefA	-	-	-	-	-	-	-	-	-	-	-	MS_channel
PYH2_k127_5397083_1	595537.Varpa_1072	2.324e-23	104.0	COG1176@1|root,COG1176@2|Bacteria,1MU1Y@1224|Proteobacteria,2VK8I@28216|Betaproteobacteria,4AD35@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
PYH2_k127_5397083_0	595537.Varpa_1073	2.259e-166	530.0	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2VICQ@28216|Betaproteobacteria,4AAM0@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
PYH2_k127_5397083_2	945543.VIBR0546_12222	1.01e-10	65.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,1RNPX@1236|Gammaproteobacteria,1XU0R@135623|Vibrionales	135623|Vibrionales	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
PYH2_k127_540559_0	987059.RBXJA2T_06995	4.59e-223	696.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,1KITH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
PYH2_k127_540559_1	395495.Lcho_0746	1.635e-195	621.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria,1KJ4N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
PYH2_k127_540559_2	864051.BurJ1DRAFT_1250	5.698e-189	600.0	COG0477@1|root,COG2814@2|Bacteria,1R3YS@1224|Proteobacteria,2VQBS@28216|Betaproteobacteria,1KNDV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_540559_3	987059.RBXJA2T_07015	3.171e-104	350.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2VKF6@28216|Betaproteobacteria,1KJVZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	ugpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
PYH2_k127_540559_4	864051.BurJ1DRAFT_1252	6.524e-51	183.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,1KKEZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	ugpC	-	3.6.3.20	ko:K05816,ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
PYH2_k127_5409511_0	266264.Rmet_3489	9.081e-271	840.0	COG0506@1|root,COG4230@1|root,COG0506@2|Bacteria,COG4230@2|Bacteria,1MV93@1224|Proteobacteria,2VITK@28216|Betaproteobacteria,1K323@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.3.8.7,1.5.5.2	ko:K00249,ko:K00294,ko:K13821	ko00071,ko00250,ko00280,ko00330,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00250,map00280,map00330,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00245,R00707,R00708,R00924,R01175,R01253,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04444,R04445,R04751,R04754,R05051	RC00052,RC00068,RC00076,RC00080,RC00083,RC00095,RC00148,RC00216,RC00242,RC00246,RC00255	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	Aldedh,Pro_dh,Pro_dh-DNA_bdg
PYH2_k127_542917_1	1265502.KB905936_gene2683	4.179e-124	402.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,4AARI@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
PYH2_k127_542917_2	864051.BurJ1DRAFT_2793	3.207e-91	306.0	COG2862@1|root,COG2862@2|Bacteria,1RANN@1224|Proteobacteria,2VK3P@28216|Betaproteobacteria,1KK23@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	UPF0114 protein	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
PYH2_k127_542917_0	338969.Rfer_2582	9.546e-165	528.0	COG3004@1|root,COG3004@2|Bacteria,1MW15@1224|Proteobacteria,2VIPV@28216|Betaproteobacteria,4ABFT@80864|Comamonadaceae	28216|Betaproteobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1,Thioredoxin_4
PYH2_k127_542917_3	395495.Lcho_3065	1.765e-13	71.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,1KIZQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
PYH2_k127_5440885_0	399795.CtesDRAFT_PD0869	0.0	1148.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,2VKDG@28216|Betaproteobacteria,4ABGP@80864|Comamonadaceae	28216|Betaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
PYH2_k127_5440885_6	543728.Vapar_4114	6.838e-82	278.0	COG2193@1|root,COG2193@2|Bacteria,1RAQ8@1224|Proteobacteria,2VQHR@28216|Betaproteobacteria,4ADG1@80864|Comamonadaceae	28216|Betaproteobacteria	P	Ferritin, Dps family protein	bfr3	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
PYH2_k127_5440885_8	338969.Rfer_2343	1.093e-35	139.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VUHT@28216|Betaproteobacteria,4AF5X@80864|Comamonadaceae	28216|Betaproteobacteria	S	SMART Transport-associated and nodulation region	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
PYH2_k127_5440885_7	1158292.JPOE01000002_gene1943	6.72e-36	138.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,1KNXM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
PYH2_k127_5440885_4	397945.Aave_3990	2.957e-129	420.0	COG1305@1|root,COG1305@2|Bacteria,1MWAI@1224|Proteobacteria,2VIWG@28216|Betaproteobacteria,4AAVQ@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PYH2_k127_5440885_1	296591.Bpro_2297	0.0	1006.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,4AAUE@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD3	-	4.2.1.25,4.2.1.82,4.2.1.9	ko:K01687,ko:K13875,ko:K22186	ko00040,ko00053,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00053,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R02522,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH2_k127_5440885_5	420324.KI911965_gene507	2.688e-128	412.0	COG0684@1|root,COG0684@2|Bacteria,1MUWV@1224|Proteobacteria,2TU1X@28211|Alphaproteobacteria,1JTAU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	H	Aldolase/RraA	MA20_39210	-	-	-	-	-	-	-	-	-	-	-	RraA-like
PYH2_k127_5440885_2	365046.Rta_15440	1.157e-149	479.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP9X@28216|Betaproteobacteria,4AA72@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_5440885_3	864051.BurJ1DRAFT_4619	1.555e-130	421.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,2W9V4@28216|Betaproteobacteria,1KMME@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Malate/L-lactate dehydrogenase	-	-	1.1.1.338	ko:K16844	ko00270,ko01120,map00270,map01120	-	R07137	RC00031	ko00000,ko00001,ko01000	-	-	-	Ldh_2
PYH2_k127_5450343_2	987059.RBXJA2T_14826	6.625e-134	434.0	COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,2VKGY@28216|Betaproteobacteria,1KKVM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Aldo/keto reductase family	ydhF	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PYH2_k127_5450343_0	987059.RBXJA2T_07933	6.286e-248	778.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2VJGS@28216|Betaproteobacteria,1KIX6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	major facilitator superfamily	emrB	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
PYH2_k127_5450343_1	358220.C380_12495	2.479e-158	510.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria,4AAZA@80864|Comamonadaceae	28216|Betaproteobacteria	V	secretion protein HlyD family	emrA	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
PYH2_k127_5450343_3	296591.Bpro_3236	1.582e-74	254.0	COG1538@1|root,COG1538@2|Bacteria,1MUZZ@1224|Proteobacteria,2VH6M@28216|Betaproteobacteria,4AAFH@80864|Comamonadaceae	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT	-	-	-	-	-	-	-	-	-	-	-	-	OEP
PYH2_k127_5464822_2	983917.RGE_44670	2.028e-17	88.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,2VQ2A@28216|Betaproteobacteria,1KMJM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
PYH2_k127_5464822_1	1286631.X805_40720	1.937e-118	384.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,1KITI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
PYH2_k127_5464822_0	420662.Mpe_A0269	1.164e-196	619.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,1KK40@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_5473073_0	864051.BurJ1DRAFT_3520	3.073e-166	530.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2VH3Z@28216|Betaproteobacteria,1KJRU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	alcohol dehydrogenase	qor	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_5473073_1	350054.Mflv_0928	8.842e-37	143.0	COG1848@1|root,COG1848@2|Bacteria,2IJ89@201174|Actinobacteria,239HU@1762|Mycobacteriaceae	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
PYH2_k127_5473073_3	1123065.ATWL01000025_gene1859	3.253e-16	81.0	2DSMH@1|root,33GPM@2|Bacteria,2GR8G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5473073_2	153948.NAL212_0060	4.046e-26	107.0	COG2944@1|root,COG2944@2|Bacteria,1PT1K@1224|Proteobacteria,2WAD4@28216|Betaproteobacteria,374HD@32003|Nitrosomonadales	28216|Betaproteobacteria	K	sequence-specific DNA binding	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	-
PYH2_k127_5480847_0	395495.Lcho_3844	0.0	1114.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,1KJWN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
PYH2_k127_5480847_4	983917.RGE_21880	8.044e-68	250.0	COG3016@1|root,COG3016@2|Bacteria,1NXYQ@1224|Proteobacteria,2VTNU@28216|Betaproteobacteria,1KPAY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
PYH2_k127_5480847_2	1265502.KB905932_gene1903	7.453e-211	669.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,2VICE@28216|Betaproteobacteria,4ABG9@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,NUDIX
PYH2_k127_5480847_1	864051.BurJ1DRAFT_3959	6.45e-211	661.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1KITF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_5480847_5	1121918.ARWE01000001_gene2240	6.79e-49	177.0	COG1359@1|root,COG1359@2|Bacteria,1N2BB@1224|Proteobacteria,42ZU2@68525|delta/epsilon subdivisions,2WVEC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5480847_3	1123504.JQKD01000029_gene4191	1.295e-127	419.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VHV1@28216|Betaproteobacteria,4ABAB@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldo keto reductase	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
PYH2_k127_5487819_1	420662.Mpe_A1615	1.97e-115	377.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2VHNW@28216|Betaproteobacteria,1KJ3A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
PYH2_k127_5487819_0	1235457.C404_10925	1.378e-196	631.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,1K3BG@119060|Burkholderiaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
PYH2_k127_5487819_2	864051.BurJ1DRAFT_2528	2.355e-81	275.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,2VJ2N@28216|Betaproteobacteria,1KKM7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Polyhydroxyalkanoate synthesis repressor	phaR	-	-	-	-	-	-	-	-	-	-	-	PHB_acc,PHB_acc_N
PYH2_k127_5487819_3	688245.CtCNB1_2006	8.899e-21	95.0	COG4974@1|root,COG4974@2|Bacteria,1R1HJ@1224|Proteobacteria,2VP28@28216|Betaproteobacteria,4AD72@80864|Comamonadaceae	28216|Betaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PYH2_k127_5516392_1	864051.BurJ1DRAFT_3647	2.201e-65	230.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria,2VK1S@28216|Betaproteobacteria,1KIZD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
PYH2_k127_5516392_0	1100720.ALKN01000045_gene223	2.708e-144	482.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,4AAJQ@80864|Comamonadaceae	28216|Betaproteobacteria	H	TonB-dependent receptor plug	btuB	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug,TonB_dep_Rec
PYH2_k127_5516392_4	395495.Lcho_2667	1.517e-18	97.0	2E3H4@1|root,32YFT@2|Bacteria,1N8PU@1224|Proteobacteria,2VVRT@28216|Betaproteobacteria,1KMMX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ZapB
PYH2_k127_5516392_3	420662.Mpe_A2311	1.195e-31	126.0	COG3027@1|root,COG3027@2|Bacteria,1PTHR@1224|Proteobacteria,2VTX2@28216|Betaproteobacteria,1KME5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
PYH2_k127_5516392_2	1123393.KB891316_gene2045	7.498e-61	213.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,1KS9K@119069|Hydrogenophilales	119069|Hydrogenophilales	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
PYH2_k127_5525940_6	666684.AfiDRAFT_3224	7.735e-14	72.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2TS02@28211|Alphaproteobacteria,3JV3Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008152,GO:0009987,GO:0015672,GO:0016491,GO:0017144,GO:0030001,GO:0034220,GO:0034641,GO:0042723,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071704,GO:0071804,GO:0071805,GO:0072527,GO:0098655,GO:0098660,GO:0098662,GO:1901360,GO:1901564	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
PYH2_k127_5525940_2	983917.RGE_35710	6.858e-94	311.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,1KITD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
PYH2_k127_5525940_4	395495.Lcho_4099	2.27e-50	188.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VRBJ@28216|Betaproteobacteria,1KKWN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_5525940_0	864051.BurJ1DRAFT_1656	0.0	1133.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,1KJBQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
PYH2_k127_5525940_5	1286631.X805_31290	3.698e-32	128.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,1KM8K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
PYH2_k127_5525940_1	864051.BurJ1DRAFT_1658	2.812e-103	343.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,1KJ6J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
PYH2_k127_5525940_3	864051.BurJ1DRAFT_1662	1.747e-62	217.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,1KJSS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
PYH2_k127_5583978_4	1219076.N646_0668	8.882e-25	123.0	COG2304@1|root,COG2931@1|root,COG3209@1|root,COG3391@1|root,COG4932@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,1RNK8@1236|Gammaproteobacteria,1XSBS@135623|Vibrionales	135623|Vibrionales	Q	COG2931 RTX toxins and related Ca2 -binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,He_PIG,HemolysinCabind,VWA_2
PYH2_k127_5583978_1	582744.Msip34_1011	2.347e-175	593.0	COG2304@1|root,COG2931@1|root,COG2304@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VKA9@28216|Betaproteobacteria,2KNPI@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind,VWA_2
PYH2_k127_5583978_0	420662.Mpe_A1878	1.249e-181	591.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1MUQV@1224|Proteobacteria,2VJ24@28216|Betaproteobacteria,1KJFT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	yfgF	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,LapD_MoxY_N
PYH2_k127_5583978_3	864051.BurJ1DRAFT_2236	8.369e-83	284.0	COG3672@1|root,COG3672@2|Bacteria,1RDQS@1224|Proteobacteria,2VR6A@28216|Betaproteobacteria,1KKQ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial transglutaminase-like cysteine proteinase BTLCP	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C93
PYH2_k127_5583978_2	420662.Mpe_A1880	7.093e-173	555.0	COG1538@1|root,COG1538@2|Bacteria,1MYX2@1224|Proteobacteria,2VKDN@28216|Betaproteobacteria,1KJZ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC family	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP,OmpA
PYH2_k127_5584049_2	420662.Mpe_A1031	7.64e-137	443.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2VIK1@28216|Betaproteobacteria,1KJ25@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Type II secretory pathway, component ExeA	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
PYH2_k127_5584049_0	987059.RBXJA2T_16177	7.098e-278	861.0	COG2010@1|root,COG3391@1|root,COG2010@2|Bacteria,COG3391@2|Bacteria,1PYK3@1224|Proteobacteria,2VIU7@28216|Betaproteobacteria,1KJHT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome D1 heme domain	nirN	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Cytochrome_CBB3
PYH2_k127_5584049_1	987059.RBXJA2T_16172	2.158e-205	643.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria,1KJZA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Radical SAM	nirJ	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
PYH2_k127_5584049_4	395495.Lcho_1447	3.925e-73	254.0	COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,2VR9X@28216|Betaproteobacteria,1KKV4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	transcriptional regulator AsnC family	nirH	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
PYH2_k127_5584049_5	748280.NH8B_1427	6.652e-52	192.0	COG1522@1|root,COG1522@2|Bacteria,1RCY6@1224|Proteobacteria,2VR9X@28216|Betaproteobacteria	28216|Betaproteobacteria	K	transcriptional regulator AsnC family	nirH	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
PYH2_k127_5584049_3	395495.Lcho_1445	7.176e-101	334.0	COG1522@1|root,COG1522@2|Bacteria,1NVYY@1224|Proteobacteria,2VHP8@28216|Betaproteobacteria,1KN1X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	COG1522 Transcriptional regulators	nirD	-	-	-	-	-	-	-	-	-	-	-	HTH_AsnC-type
PYH2_k127_5599113_4	1244869.H261_13384	6.122e-31	126.0	2CRRJ@1|root,32SPH@2|Bacteria,1NYMT@1224|Proteobacteria,2UTVD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3307)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3307
PYH2_k127_5599113_2	864051.BurJ1DRAFT_0727	2.51e-145	466.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,1KMYK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_5599113_3	859657.RPSI07_mp1259	9.137e-55	196.0	COG0346@1|root,COG0346@2|Bacteria,1RH3J@1224|Proteobacteria,2VRD4@28216|Betaproteobacteria,1K71G@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA3	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH2_k127_5599113_1	1095769.CAHF01000011_gene2120	8.65e-206	648.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2VI2F@28216|Betaproteobacteria,4762V@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
PYH2_k127_5599113_0	543728.Vapar_1312	5.554e-219	681.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VKD1@28216|Betaproteobacteria,4AADX@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Acyl-CoA dehydrogenase	acd12	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_5609634_2	864051.BurJ1DRAFT_2770	1.037e-87	293.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2W9GX@28216|Betaproteobacteria,1KNPZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
PYH2_k127_5609634_0	365046.Rta_12700	1.454e-257	813.0	COG4091@1|root,COG4091@2|Bacteria,1MUZX@1224|Proteobacteria,2VI2Z@28216|Betaproteobacteria,4AAKE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,NAD_binding_3,SAF
PYH2_k127_5609634_1	1157708.KB907450_gene6512	1.217e-161	512.0	COG5285@1|root,COG5285@2|Bacteria,1MWD5@1224|Proteobacteria,2VM24@28216|Betaproteobacteria,4ABN5@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	1.14.11.55	ko:K10674	ko00260,ko01120,map00260,map01120	-	R08050	RC00661	ko00000,ko00001,ko01000	-	-	-	PhyH
PYH2_k127_5609634_3	1288494.EBAPG3_12200	3.425e-30	126.0	COG2010@1|root,COG2010@2|Bacteria,1NF1C@1224|Proteobacteria,2VVP1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5609634_4	1100720.ALKN01000031_gene1210	2.718e-07	59.0	2BVW3@1|root,2Z7TB@2|Bacteria,1MY60@1224|Proteobacteria,2VJKN@28216|Betaproteobacteria,4AAV8@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM 5-nucleotidase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5-nucleotidase
PYH2_k127_5613361_6	983917.RGE_46700	1.159e-215	679.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,1KJ6W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
PYH2_k127_5613361_17	983917.RGE_46710	1.231e-60	218.0	28NWD@1|root,2ZBU8@2|Bacteria,1RGNH@1224|Proteobacteria,2VRUN@28216|Betaproteobacteria,1KKWS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
PYH2_k127_5613361_14	1005048.CFU_4126	6.096e-77	276.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,473A7@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
PYH2_k127_5613361_11	983917.RGE_46730	1.54e-129	417.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,1KJAC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	exodeoxyribonuclease III	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
PYH2_k127_5613361_12	395495.Lcho_4053	1.035e-109	357.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,2VHMC@28216|Betaproteobacteria,1KJIH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Metallo-beta-lactamase superfamily	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH2_k127_5613361_13	395495.Lcho_4104	1.212e-108	359.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,2VHTB@28216|Betaproteobacteria,1KK3K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
PYH2_k127_5613361_5	987059.RBXJA2T_07643	6.796e-251	782.0	COG4114@1|root,COG4114@2|Bacteria,1QZYT@1224|Proteobacteria,2WHQG@28216|Betaproteobacteria,1KK2K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	Acatn
PYH2_k127_5613361_16	864051.BurJ1DRAFT_4988	2.917e-64	230.0	COG5662@1|root,COG5662@2|Bacteria,1RK1X@1224|Proteobacteria,2VQDP@28216|Betaproteobacteria,1KMGD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	transmembrane transcriptional regulator (Anti-sigma factor)	prtR	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
PYH2_k127_5613361_18	864051.BurJ1DRAFT_4989	2.39e-54	196.0	COG1595@1|root,COG1595@2|Bacteria,1MZMC@1224|Proteobacteria,2VSEK@28216|Betaproteobacteria,1KMKJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE8	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PYH2_k127_5613361_15	420662.Mpe_A3697	1.335e-72	256.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2VQA1@28216|Betaproteobacteria,1KKWU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PYH2_k127_5613361_19	1179778.PMM47T1_12648	0.0007598	50.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,1S3GW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_5613361_2	864051.BurJ1DRAFT_4993	4.208e-281	895.0	COG0365@1|root,COG0365@2|Bacteria,1MUX7@1224|Proteobacteria,2VKAN@28216|Betaproteobacteria,1KJHP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
PYH2_k127_5613361_7	987059.RBXJA2T_07623	1.656e-201	653.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KJPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
PYH2_k127_5613361_3	983917.RGE_46790	2.041e-261	835.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KKIK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
PYH2_k127_5613361_0	987059.RBXJA2T_07623	0.0	1050.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KJPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
PYH2_k127_5613361_9	983917.RGE_46810	1.099e-157	505.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VN7U@28216|Betaproteobacteria,1KJSF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	gsiC_8	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_5613361_10	983917.RGE_46820	2.007e-156	517.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,1KKHI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH2_k127_5613361_1	987059.RBXJA2T_07608	8.408e-285	902.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,1KJMZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	gsiA	-	-	ko:K02031,ko:K02032,ko:K10823,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00349,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.21,3.A.1.5.24,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PYH2_k127_5613361_8	864051.BurJ1DRAFT_5004	2.791e-163	520.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1KN9J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_5613361_4	365044.Pnap_0267	4.211e-256	800.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VMJK@28216|Betaproteobacteria,4AG8M@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PYH2_k127_5617911_3	983917.RGE_39200	2.452e-131	427.0	COG0842@1|root,COG0842@2|Bacteria,1MVUG@1224|Proteobacteria,2VJWU@28216|Betaproteobacteria,1KJA6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
PYH2_k127_5617911_2	983917.RGE_40680	4.93e-132	431.0	COG0683@1|root,COG0683@2|Bacteria,1MWGW@1224|Proteobacteria,2VK6Q@28216|Betaproteobacteria,1KJ61@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH2_k127_5617911_4	395495.Lcho_3851	9.129e-121	395.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2VM1W@28216|Betaproteobacteria,1KK7W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,Lactonase
PYH2_k127_5617911_5	395495.Lcho_1793	5.903e-110	360.0	COG1131@1|root,COG1131@2|Bacteria,1MX56@1224|Proteobacteria,2VQIQ@28216|Betaproteobacteria,1KJDW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_5617911_7	864051.BurJ1DRAFT_0145	4.697e-103	336.0	COG1142@1|root,COG1142@2|Bacteria,1MWE1@1224|Proteobacteria,2VJ9U@28216|Betaproteobacteria,1KKF6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K05796	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_11,Fer4_4,Fer4_6,Fer4_9
PYH2_k127_5617911_0	1265502.KB905933_gene2062	0.0	1133.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,2VJ8P@28216|Betaproteobacteria,4AC24@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldehyde ferredoxin oxidoreductase	aorA	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
PYH2_k127_5617911_1	395495.Lcho_1818	3.181e-208	654.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,2WH5F@28216|Betaproteobacteria,1KPCV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
PYH2_k127_5617911_9	395495.Lcho_1819	1.685e-29	119.0	COG2104@1|root,COG2104@2|Bacteria,1N9VX@1224|Proteobacteria,2VVYE@28216|Betaproteobacteria,1KMP9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Mut7-C ubiquitin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS,Ub-Mut7C
PYH2_k127_5617911_10	395495.Lcho_1820	1.954e-25	109.0	2EBXW@1|root,335X8@2|Bacteria,1NBMB@1224|Proteobacteria,2VWB7@28216|Betaproteobacteria,1KMJ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5617911_6	1440774.Y900_010000	1.21e-108	362.0	COG2199@1|root,COG3706@2|Bacteria,2IB0W@201174|Actinobacteria,235JY@1762|Mycobacteriaceae	201174|Actinobacteria	T	Diguanylate cyclase with PAS PAC sensor	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF,PAS_3,PAS_4,PAS_8,PAS_9
PYH2_k127_5617911_8	1041139.KB902685_gene1322	1.413e-31	125.0	COG5470@1|root,COG5470@2|Bacteria,1PJI0@1224|Proteobacteria,2U9BT@28211|Alphaproteobacteria,4BG76@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
PYH2_k127_5617911_11	864051.BurJ1DRAFT_4935	5.391e-20	94.0	2BYHI@1|root,3432J@2|Bacteria,1NYUU@1224|Proteobacteria,2W3H2@28216|Betaproteobacteria,1KNRZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5635349_1	1158292.JPOE01000002_gene1844	3.743e-155	496.0	COG3961@1|root,COG3961@2|Bacteria,1MW2F@1224|Proteobacteria,2VIQN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the TPP enzyme family	ipdC	-	4.1.1.74	ko:K04103	ko00380,ko01100,map00380,map01100	-	R01974	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_5635349_0	1286631.X805_00270	0.0	1464.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,1KJC4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC
PYH2_k127_5638861_3	1380394.JADL01000013_gene735	2.947e-120	394.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,2JQ04@204441|Rhodospirillales	204441|Rhodospirillales	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PYH2_k127_5638861_2	391735.Veis_4148	1.476e-238	767.0	COG0624@1|root,COG0624@2|Bacteria,1MVUX@1224|Proteobacteria,2VHQ8@28216|Betaproteobacteria,4AAK9@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM amidase, hydantoinase carbamoylase family	amaB1	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
PYH2_k127_5638861_0	358220.C380_04155	1.501e-271	841.0	COG0044@1|root,COG0044@2|Bacteria,1MW10@1224|Proteobacteria,2VJZV@28216|Betaproteobacteria,4ABSY@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM amidohydrolase	dht	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
PYH2_k127_5638861_1	358220.C380_04145	1.596e-240	748.0	COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1MXER@1224|Proteobacteria,2VK6N@28216|Betaproteobacteria,4AD1V@80864|Comamonadaceae	28216|Betaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	yeiA	-	1.3.1.1,1.3.1.14	ko:K17723,ko:K17828	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046,M00051	R00977,R01414,R01869,R11026	RC00051,RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh,Fer4_21,Fer4_6
PYH2_k127_5638861_4	358220.C380_04140	2.663e-112	366.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VNEZ@28216|Betaproteobacteria,4AJ3N@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	yeiT	-	1.3.1.1	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	M00046	R00977,R01414,R11026	RC00072,RC00123	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,Pyr_redox_2
PYH2_k127_565678_1	1280950.HJO_02265	1.69e-35	144.0	2DX57@1|root,343DX@2|Bacteria,1P1B5@1224|Proteobacteria,2UV43@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_565678_0	1242864.D187_003640	1.421e-40	164.0	COG3055@1|root,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
PYH2_k127_5659942_3	420662.Mpe_A0810	4.19e-35	135.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,1KJBE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_5659942_1	395495.Lcho_1596	6.791e-148	478.0	COG2204@1|root,COG4585@1|root,COG2204@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,1KJJ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9,Response_reg
PYH2_k127_5659942_2	864051.BurJ1DRAFT_4779	6.034e-107	358.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ9H@28216|Betaproteobacteria,1KIX1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH2_k127_5659942_4	983917.RGE_16840	6.096e-34	136.0	COG1677@1|root,COG1677@2|Bacteria,1N6RZ@1224|Proteobacteria,2VVQF@28216|Betaproteobacteria,1KMDQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar hook-basal body complex protein FliE	fliE	-	-	ko:K02408	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliE
PYH2_k127_5659942_0	420662.Mpe_A0565	5.84e-149	477.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria,1KJ2E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
PYH2_k127_5665764_3	395495.Lcho_1801	2.795e-71	242.0	COG3181@1|root,COG3181@2|Bacteria,1N7C4@1224|Proteobacteria,2VHNI@28216|Betaproteobacteria,1KK7M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_5665764_2	472759.Nhal_0303	1.83e-78	265.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,1S1HV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH2_k127_5665764_1	1041139.KB902724_gene4151	4.075e-82	280.0	COG0625@1|root,COG0625@2|Bacteria,1RK1K@1224|Proteobacteria,2V5U1@28211|Alphaproteobacteria,4BGB5@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C,GST_N
PYH2_k127_5665764_0	864051.BurJ1DRAFT_4910	3.914e-150	481.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,2VHIK@28216|Betaproteobacteria,1KIZ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
PYH2_k127_5665764_4	395495.Lcho_1822	2.534e-63	220.0	COG1910@1|root,COG2005@1|root,COG1910@2|Bacteria,COG2005@2|Bacteria,1MVS4@1224|Proteobacteria,2VH5J@28216|Betaproteobacteria,1KK19@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PBP superfamily domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_1,PBP_like
PYH2_k127_5692573_0	1157708.KB907453_gene4394	1.763e-79	277.0	COG3391@1|root,COG3391@2|Bacteria,1R3YF@1224|Proteobacteria,2VMFE@28216|Betaproteobacteria,4AG1Y@80864|Comamonadaceae	28216|Betaproteobacteria	S	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
PYH2_k127_5692573_1	338969.Rfer_2330	6.334e-71	246.0	COG2050@1|root,COG2050@2|Bacteria,1N57X@1224|Proteobacteria,2VTJB@28216|Betaproteobacteria,4AHYH@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
PYH2_k127_5699794_5	1268622.AVS7_02538	1.437e-142	462.0	COG3616@1|root,COG3616@2|Bacteria,1MVQE@1224|Proteobacteria,2VIUU@28216|Betaproteobacteria,4ACPR@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM alanine racemase domain protein	-	-	4.1.2.42	ko:K19967	-	-	-	-	ko00000,ko01000	-	-	-	Ala_racemase_N,D-ser_dehydrat
PYH2_k127_5699794_8	204773.HEAR0393	6.529e-102	339.0	COG2116@1|root,COG2116@2|Bacteria,1MU0W@1224|Proteobacteria,2VKMF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Formate nitrite	-	-	-	ko:K02598,ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3,1.A.16.3	-	-	Form_Nir_trans
PYH2_k127_5699794_0	420662.Mpe_A0327	1.114e-191	604.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,1KKGH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
PYH2_k127_5699794_12	1123487.KB892839_gene152	5.772e-40	154.0	COG2847@1|root,COG2847@2|Bacteria,1MZ3M@1224|Proteobacteria,2VTY7@28216|Betaproteobacteria,2KWMU@206389|Rhodocyclales	206389|Rhodocyclales	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
PYH2_k127_5699794_9	864051.BurJ1DRAFT_4500	3.111e-82	278.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,1KJKB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
PYH2_k127_5699794_6	864051.BurJ1DRAFT_4499	1.6e-110	361.0	COG2197@1|root,COG2197@2|Bacteria,1RGXD@1224|Proteobacteria,2WEGP@28216|Betaproteobacteria,1KIYQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH2_k127_5699794_1	983917.RGE_44200	1.281e-181	587.0	COG4585@1|root,COG4585@2|Bacteria,1R1TC@1224|Proteobacteria,2VHUA@28216|Betaproteobacteria,1KIW1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3
PYH2_k127_5699794_4	987059.RBXJA2T_16292	7.741e-143	463.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,2VH9V@28216|Betaproteobacteria,1KJD3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PhoH-like protein	ybeZ	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
PYH2_k127_5699794_10	420662.Mpe_A3240	2.31e-54	197.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,1KKVR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
PYH2_k127_5699794_7	1100721.ALKO01000017_gene1649	1.204e-109	367.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VIII@28216|Betaproteobacteria,4ABDN@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_5699794_3	987059.RBXJA2T_16277	4.656e-156	499.0	COG0598@1|root,COG0598@2|Bacteria,1NWUN@1224|Proteobacteria,2VKVR@28216|Betaproteobacteria,1KK24@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
PYH2_k127_5699794_2	296591.Bpro_0245	1.558e-173	550.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,4AB2M@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the ALAD family	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
PYH2_k127_5699794_11	420662.Mpe_A0307	1.651e-53	194.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,1KKV6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
PYH2_k127_5699794_13	864051.BurJ1DRAFT_4492	1.936e-32	130.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,1KJNI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PYH2_k127_5706423_5	1454004.AW11_01658	1.925e-20	91.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Thiamine pyrophosphate	porB	-	1.2.1.58,1.2.7.1	ko:K00170,ko:K18356	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_11,Fer4_6,TPP_enzyme_C
PYH2_k127_5706423_0	864051.BurJ1DRAFT_4545	4.255e-228	716.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria,1KK3S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyruvate:ferredoxin oxidoreductase core domain II	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
PYH2_k127_5706423_2	395495.Lcho_2149	1.761e-90	305.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria,1KKPN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.1.58,1.2.7.1	ko:K00172,ko:K18357	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
PYH2_k127_5706423_1	1276756.AUEX01000006_gene3121	1.142e-104	351.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,2VJ5U@28216|Betaproteobacteria	28216|Betaproteobacteria	S	RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
PYH2_k127_5706423_3	861299.J421_0542	2.065e-64	228.0	COG3576@1|root,COG3576@2|Bacteria	2|Bacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
PYH2_k127_5706423_4	395495.Lcho_4061	2.399e-42	165.0	COG0346@1|root,COG0346@2|Bacteria,1RABQ@1224|Proteobacteria,2VS4J@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH2_k127_5706423_6	1318628.MARLIPOL_16289	1.233e-11	70.0	2F7U0@1|root,34084@2|Bacteria,1NZJ4@1224|Proteobacteria	1318628.MARLIPOL_16289|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5758157_3	420662.Mpe_A0595	8.38e-78	267.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria,1KK1P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
PYH2_k127_5758157_2	296591.Bpro_1122	4.299e-116	379.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2VJVA@28216|Betaproteobacteria,4A9TB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692,ko:K01715	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH2_k127_5758157_4	1265502.KB905932_gene1855	4.019e-58	207.0	COG0259@1|root,COG0259@2|Bacteria,1RIAU@1224|Proteobacteria,2VSMA@28216|Betaproteobacteria,4AICC@80864|Comamonadaceae	28216|Betaproteobacteria	H	Pyridoxamine 5'-phosphate oxidase	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	Putative_PNPOx,Pyridox_oxase_2
PYH2_k127_5758157_0	983917.RGE_41580	1.139e-254	795.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,1KJZM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
PYH2_k127_5758157_1	1121035.AUCH01000001_gene2089	6.223e-140	449.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,2KUMY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
PYH2_k127_575922_1	479433.Caci_6410	0.0002174	54.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,HTH_31,NB-ARC,TPR_12,Trans_reg_C
PYH2_k127_575922_0	1002340.AFCF01000033_gene3890	3.096e-264	834.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2TX3Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
PYH2_k127_5777011_0	887062.HGR_09915	3.174e-184	579.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,4AAZM@80864|Comamonadaceae	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
PYH2_k127_5780354_4	864051.BurJ1DRAFT_3697	1.084e-170	550.0	COG1994@1|root,COG1994@2|Bacteria,1MW9I@1224|Proteobacteria,2VIUH@28216|Betaproteobacteria,1KK98@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	membrane-associated Zn-dependent proteases 1	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2
PYH2_k127_5780354_3	864051.BurJ1DRAFT_3696	1.625e-188	606.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2VH3J@28216|Betaproteobacteria,1KM64@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23
PYH2_k127_5780354_27	644107.SL1157_0518	5.891e-11	63.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5780354_1	864051.BurJ1DRAFT_0397	1.232e-247	778.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,1KJ94@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
PYH2_k127_5780354_6	1265502.KB905956_gene147	1.268e-113	373.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,4AA20@80864|Comamonadaceae	28216|Betaproteobacteria	V	Transport permease protein	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
PYH2_k127_5780354_5	1265502.KB905956_gene146	9.695e-145	464.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,4ABWS@80864|Comamonadaceae	28216|Betaproteobacteria	V	Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
PYH2_k127_5780354_18	420662.Mpe_A3416	2.259e-62	216.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,1KKYA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
PYH2_k127_5780354_2	1265502.KB905956_gene144	6.17e-195	610.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,4AA16@80864|Comamonadaceae	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
PYH2_k127_5780354_7	864051.BurJ1DRAFT_0394	3.58e-112	364.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,1KIUD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
PYH2_k127_5780354_12	864051.BurJ1DRAFT_0393	1.422e-76	257.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,1KKRV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
PYH2_k127_5780354_16	987059.RBXJA2T_02235	1.023e-67	231.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,1KKTC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
PYH2_k127_5780354_26	987059.RBXJA2T_02230	2.608e-15	75.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria,1KMSK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
PYH2_k127_5780354_22	987059.RBXJA2T_02225	2.24e-40	149.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,1KM9P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
PYH2_k127_5780354_0	987059.RBXJA2T_02220	2.111e-258	799.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,1KJGH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
PYH2_k127_5780354_17	358220.C380_21865	1.269e-62	220.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,4ADGY@80864|Comamonadaceae	28216|Betaproteobacteria	J	binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
PYH2_k127_5780354_25	1121116.KB894766_gene251	6.735e-22	99.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,4AFGA@80864|Comamonadaceae	28216|Betaproteobacteria	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
PYH2_k127_5780354_9	983917.RGE_03470	1.232e-87	292.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,1KKM6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
PYH2_k127_5780354_20	1265502.KB905956_gene135	3.023e-48	175.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,4AE21@80864|Comamonadaceae	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
PYH2_k127_5780354_10	864051.BurJ1DRAFT_0383	1.386e-85	286.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,1KJY4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
PYH2_k127_5780354_15	420662.Mpe_A3429	2.402e-68	236.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,1KKUW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
PYH2_k127_5780354_21	864051.BurJ1DRAFT_0381	1.384e-46	169.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,1KM1V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
PYH2_k127_5780354_8	1286631.X805_36650	1.05e-98	331.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,1KJRC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
PYH2_k127_5780354_19	1538295.JY96_07620	2.715e-51	183.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,1KM1K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
PYH2_k127_5780354_14	420662.Mpe_A3432	8.459e-70	237.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2VR2N@28216|Betaproteobacteria,1KM02@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
PYH2_k127_5780354_11	864051.BurJ1DRAFT_0377	1.506e-79	271.0	COG0678@1|root,COG0678@2|Bacteria,1MU0H@1224|Proteobacteria,2VQDH@28216|Betaproteobacteria,1KKQ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Redoxin	ahp1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	Redoxin
PYH2_k127_5780354_23	864051.BurJ1DRAFT_0376	2.346e-35	145.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,1KMEY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
PYH2_k127_5780354_24	1265502.KB905956_gene126	2.79e-22	102.0	COG0255@1|root,COG0255@2|Bacteria,1N6PR@1224|Proteobacteria,2VVNT@28216|Betaproteobacteria,4AFHC@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
PYH2_k127_5780354_13	864051.BurJ1DRAFT_0374	6.426e-75	255.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,1KKJY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
PYH2_k127_5781841_5	1042377.AFPJ01000050_gene1322	1.079e-24	103.0	COG0050@1|root,COG0050@2|Bacteria	2|Bacteria	J	translation elongation factor activity	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
PYH2_k127_5781841_3	1123487.KB892835_gene3640	1.289e-55	196.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,2VSDQ@28216|Betaproteobacteria,2KWNB@206389|Rhodocyclales	206389|Rhodocyclales	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
PYH2_k127_5781841_1	76114.ebA3828	4.098e-97	322.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,2VJ3V@28216|Betaproteobacteria,2KV3R@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
PYH2_k127_5781841_2	497321.C664_09130	6.663e-87	293.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,2VHS6@28216|Betaproteobacteria,2KVFP@206389|Rhodocyclales	206389|Rhodocyclales	J	50S ribosomal protein L4	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
PYH2_k127_5781841_4	76114.ebB125	3.437e-37	152.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,2VU1C@28216|Betaproteobacteria,2KWRX@206389|Rhodocyclales	206389|Rhodocyclales	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
PYH2_k127_5781841_0	1123393.KB891318_gene2137	5.765e-113	368.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,1KRH9@119069|Hydrogenophilales	119069|Hydrogenophilales	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
PYH2_k127_5797259_0	887062.HGR_04998	9.279e-319	982.0	COG0644@1|root,COG2440@1|root,COG0644@2|Bacteria,COG2440@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,4AA63@80864|Comamonadaceae	28216|Betaproteobacteria	C	Electron transfer flavoprotein-ubiquinone oxidoreductase	etf	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	DAO,ETF_QO,FAD_binding_2,NAD_binding_8
PYH2_k127_5797259_1	420662.Mpe_A1440	0.0009086	50.0	28KUM@1|root,2ZABC@2|Bacteria,1R683@1224|Proteobacteria,2VPU1@28216|Betaproteobacteria,1KKMU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2868)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2868,DUF3482
PYH2_k127_5800546_3	983917.RGE_23800	1.374e-67	232.0	COG5473@1|root,COG5473@2|Bacteria,1MVRU@1224|Proteobacteria,2VK3K@28216|Betaproteobacteria,1KKMW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Predicted integral membrane protein (DUF2189)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2189
PYH2_k127_5800546_4	987059.RBXJA2T_08260	3.24e-28	122.0	2DNMC@1|root,32Y3R@2|Bacteria,1N8DI@1224|Proteobacteria,2VVNN@28216|Betaproteobacteria,1KMH0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2788
PYH2_k127_5800546_2	864051.BurJ1DRAFT_2248	2.715e-142	453.0	COG1028@1|root,COG1028@2|Bacteria,1MUEV@1224|Proteobacteria,2VH8R@28216|Betaproteobacteria,1KIVJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	phbB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464	1.1.1.36	ko:K00023	ko00630,ko00650,ko01120,ko01200,map00630,map00650,map01120,map01200	M00373	R01779,R01977	RC00103,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
PYH2_k127_5800546_1	420662.Mpe_A1869	1.34e-212	664.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1KJB6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	phbA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_5800546_0	864051.BurJ1DRAFT_2247	1.692e-267	833.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,2VH50@28216|Betaproteobacteria,1KJB7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Poly(R)-hydroxyalkanoic acid synthase, class I	phbC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PhaC_N
PYH2_k127_5800546_5	420662.Mpe_A1871	1.014e-19	89.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,1KKKZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
PYH2_k127_5812151_0	395019.Bmul_1647	2.783e-178	565.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VHV4@28216|Betaproteobacteria,1K04S@119060|Burkholderiaceae	28216|Betaproteobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_5812151_4	1123377.AUIV01000029_gene620	3.194e-30	123.0	COG3603@1|root,COG3603@2|Bacteria,1RI6G@1224|Proteobacteria,1S72Y@1236|Gammaproteobacteria,1X93I@135614|Xanthomonadales	135614|Xanthomonadales	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
PYH2_k127_5812151_3	323848.Nmul_A1210	5.704e-55	198.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,3731F@32003|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
PYH2_k127_5812151_5	323848.Nmul_A1211	7.394e-10	63.0	COG3114@1|root,COG3114@2|Bacteria,1NGBM@1224|Proteobacteria,2VY1Y@28216|Betaproteobacteria,373N5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	-	-	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	-	CcmD
PYH2_k127_5812151_1	1198452.Jab_1c17710	2.962e-116	380.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
PYH2_k127_5812151_2	1266925.JHVX01000001_gene2491	1.346e-75	259.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,371Q1@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
PYH2_k127_5816191_8	1504672.669786632	1.575e-29	120.0	COG0438@1|root,COG0438@2|Bacteria,1RB3J@1224|Proteobacteria,2VJNY@28216|Betaproteobacteria,4ACVF@80864|Comamonadaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
PYH2_k127_5816191_1	365046.Rta_33600	4.636e-169	542.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,4AAPT@80864|Comamonadaceae	28216|Betaproteobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
PYH2_k127_5816191_5	420662.Mpe_A2862	4.474e-86	295.0	COG5581@1|root,COG5581@2|Bacteria,1RFI4@1224|Proteobacteria,2W8A4@28216|Betaproteobacteria,1KKKD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility	ycgR	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR
PYH2_k127_5816191_7	864051.BurJ1DRAFT_1319	2.072e-39	150.0	COG1516@1|root,COG1516@2|Bacteria,1N4VX@1224|Proteobacteria,2VU8N@28216|Betaproteobacteria,1KM8H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar protein FliT	fliT	-	-	ko:K02423	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliT
PYH2_k127_5816191_6	864051.BurJ1DRAFT_1318	2.397e-47	175.0	COG1516@1|root,COG1516@2|Bacteria,1MZ3G@1224|Proteobacteria,2VU2S@28216|Betaproteobacteria,1KMEN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	flagellar protein FliS	fliS	-	-	ko:K02422	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliS
PYH2_k127_5816191_2	864051.BurJ1DRAFT_1317	1.145e-147	481.0	COG1345@1|root,COG1345@2|Bacteria,1MUVP@1224|Proteobacteria,2VHMK@28216|Betaproteobacteria,1KK2R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	fliD	-	-	ko:K02407	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_IN,FliD_C,FliD_N
PYH2_k127_5816191_3	232721.Ajs_3812	1.229e-114	376.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,4ADS1@80864|Comamonadaceae	28216|Betaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
PYH2_k127_5816191_4	1538295.JY96_16630	1.96e-114	374.0	COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,2VJTA@28216|Betaproteobacteria,1KKEX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella	fliC	-	-	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	-	-	-	ko00000,ko00001,ko02035	-	-	-	Flagellin_C,Flagellin_IN,Flagellin_N
PYH2_k127_5816191_0	864051.BurJ1DRAFT_1314	1.243e-227	723.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,1KJFC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
PYH2_k127_5816428_3	1286631.X805_35840	5.364e-63	218.0	COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,2VT83@28216|Betaproteobacteria,1KMRI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
PYH2_k127_5816428_1	864051.BurJ1DRAFT_3031	2.294e-150	486.0	COG1752@1|root,COG1752@2|Bacteria,1MU6Z@1224|Proteobacteria,2VHBX@28216|Betaproteobacteria,1KIVN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
PYH2_k127_5816428_0	420662.Mpe_A1888	0.0	1107.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,1KJAM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
PYH2_k127_5816428_2	983917.RGE_24530	2.759e-97	319.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,1KJ15@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
PYH2_k127_5816428_5	1538295.JY96_03205	3.878e-33	131.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,1KM9M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
PYH2_k127_5816428_4	864051.BurJ1DRAFT_3026	1.823e-60	210.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,1KKVN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
PYH2_k127_5816428_6	864051.BurJ1DRAFT_3025	5.125e-23	102.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,1KJGE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
PYH2_k127_5816991_2	864051.BurJ1DRAFT_3359	5.215e-147	472.0	COG1893@1|root,COG1893@2|Bacteria,1P0AW@1224|Proteobacteria,2VKYM@28216|Betaproteobacteria,1KKQN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	apbA	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
PYH2_k127_5816991_1	864051.BurJ1DRAFT_3358	2.573e-147	490.0	COG4857@1|root,COG4857@2|Bacteria,1PNY2@1224|Proteobacteria,2VQ33@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
PYH2_k127_5816991_0	864051.BurJ1DRAFT_3357	1.264e-210	666.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,1KIVQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno2	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PYH2_k127_5816991_6	338969.Rfer_4077	2.05e-26	112.0	COG4654@1|root,COG4654@2|Bacteria,1MZJM@1224|Proteobacteria,2VV99@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pfam cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
PYH2_k127_5816991_5	395495.Lcho_1338	5.326e-55	201.0	COG3005@1|root,COG3005@2|Bacteria,1MWV2@1224|Proteobacteria,2VPKX@28216|Betaproteobacteria,1KMGA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	napC	-	-	ko:K02569	-	-	-	-	ko00000	-	-	-	Cytochrom_NNT
PYH2_k127_5816991_3	1283300.ATXB01000002_gene2886	7.404e-130	439.0	COG3637@1|root,COG3637@2|Bacteria,1R42W@1224|Proteobacteria,1RYPE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative outer membrane beta-barrel porin, MtrB/PioB	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB
PYH2_k127_5816991_4	1283300.ATXB01000002_gene2887	1.355e-89	301.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria,1RZUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
PYH2_k127_5825446_1	1504672.669786473	5.106e-31	132.0	COG3597@1|root,COG3597@2|Bacteria,1QG9J@1224|Proteobacteria,2VIRR@28216|Betaproteobacteria,4AATU@80864|Comamonadaceae	28216|Betaproteobacteria	P	Tellurite resistance protein TerB	-	-	-	-	-	-	-	-	-	-	-	-	DUF533,TerB
PYH2_k127_5825446_0	1123024.AUII01000024_gene228	1.662e-108	368.0	COG2890@1|root,COG2890@2|Bacteria	2|Bacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	ko:K21786	ko00333,ko01130,map00333,map01130	M00837,M00838	R11670	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25,Methyltransf_31
PYH2_k127_5825446_2	1454004.AW11_03982	2.336e-06	59.0	2DZRB@1|root,32VGU@2|Bacteria,1NK4X@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5833301_1	864051.BurJ1DRAFT_0205	9.161e-91	304.0	COG1379@1|root,COG1379@2|Bacteria,1MVED@1224|Proteobacteria,2VJM0@28216|Betaproteobacteria,1KJW4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
PYH2_k127_5833301_2	420662.Mpe_A0248	3.275e-33	129.0	2EGTE@1|root,33AJI@2|Bacteria,1N5DW@1224|Proteobacteria,2VUCZ@28216|Betaproteobacteria,1KMN4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
PYH2_k127_5833301_0	864051.BurJ1DRAFT_0202	3.701e-245	766.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,2VK9Z@28216|Betaproteobacteria,1KJ98@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
PYH2_k127_5838665_1	365046.Rta_11770	2.709e-62	222.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria,4AD7H@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1
PYH2_k127_5838665_0	983917.RGE_46270	2.751e-128	414.0	COG3227@1|root,COG3227@2|Bacteria,1R61F@1224|Proteobacteria,2VUWX@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Thermolysin metallopeptidase, alpha-helical domain	-	-	-	ko:K20273	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
PYH2_k127_5851977_2	75379.Tint_2075	3.372e-53	190.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,2VHDY@28216|Betaproteobacteria,1KJMY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
PYH2_k127_5851977_0	864051.BurJ1DRAFT_2280	6.009e-140	452.0	COG1028@1|root,COG1028@2|Bacteria,1MXWI@1224|Proteobacteria,2VJIU@28216|Betaproteobacteria,1KJR4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	short-chain dehydrogenase	gno2	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH2_k127_5851977_1	987059.RBXJA2T_13179	7.747e-69	238.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,1KKKN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0502 family	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
PYH2_k127_5860199_8	987059.RBXJA2T_15538	9.453e-11	63.0	COG3017@1|root,COG3017@2|Bacteria,1N2F2@1224|Proteobacteria,2VUJH@28216|Betaproteobacteria,1KM9Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
PYH2_k127_5860199_1	983917.RGE_08720	2.422e-122	401.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,1KJR7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
PYH2_k127_5860199_0	987059.RBXJA2T_15528	3.1e-182	573.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,1KJRH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
PYH2_k127_5860199_2	987059.RBXJA2T_15523	4.225e-101	333.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,1KK92@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
PYH2_k127_5860199_3	768671.ThimaDRAFT_3709	2.526e-98	329.0	COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,1RQA1@1236|Gammaproteobacteria,1X0AG@135613|Chromatiales	135613|Chromatiales	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PYH2_k127_5860199_4	420662.Mpe_A3227	2.993e-89	310.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,1KJEQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
PYH2_k127_5860199_6	420662.Mpe_A3225	1.106e-41	154.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,1KMCZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
PYH2_k127_5860199_5	987059.RBXJA2T_15503	2.241e-84	286.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,1KKNP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PYH2_k127_5860199_7	365046.Rta_33480	3.697e-12	68.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,4ADP4@80864|Comamonadaceae	28216|Betaproteobacteria	L	Methyltransferase	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
PYH2_k127_5860631_21	640081.Dsui_0527	5.642e-23	101.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VVSV@28216|Betaproteobacteria,2KX9P@206389|Rhodocyclales	206389|Rhodocyclales	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
PYH2_k127_5860631_15	864051.BurJ1DRAFT_3652	1.216e-67	233.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,1KKX4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
PYH2_k127_5860631_10	395495.Lcho_2670	3.763e-122	396.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,1KJBZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH2_k127_5860631_8	1122604.JONR01000032_gene70	2.116e-168	536.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,1RY75@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
PYH2_k127_5860631_0	1411123.JQNH01000001_gene2121	0.0	1200.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2TQYI@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	CoA binding domain	MA20_15065	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
PYH2_k127_5860631_16	1297863.APJF01000005_gene1828	1.02e-61	220.0	2AI77@1|root,318MJ@2|Bacteria,1MXJB@1224|Proteobacteria,2TW9U@28211|Alphaproteobacteria,3JUTF@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5860631_2	224911.27356237	2.858e-259	807.0	COG3391@1|root,COG3391@2|Bacteria,1MXDX@1224|Proteobacteria,2TQRB@28211|Alphaproteobacteria,3JURQ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	56kDa selenium binding protein (SBP56)	-	-	-	ko:K17285	-	-	-	-	ko00000,ko04147	-	-	-	SBP56
PYH2_k127_5860631_6	375286.mma_2347	4.525e-183	582.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHB0@28216|Betaproteobacteria,476TX@75682|Oxalobacteraceae	28216|Betaproteobacteria	H	CoA-transferase family III	-	-	2.8.3.16,2.8.3.22	ko:K07749,ko:K14471,ko:K14472	ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200	M00376	R00406,R03154	RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
PYH2_k127_5860631_4	28444.JODQ01000008_gene970	1.829e-201	657.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4EI6J@85012|Streptosporangiales	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_5860631_12	1005048.CFU_2015	7.731e-91	302.0	COG0664@1|root,COG0664@2|Bacteria,1R64V@1224|Proteobacteria,2VJXN@28216|Betaproteobacteria,472QZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
PYH2_k127_5860631_13	595537.Varpa_5203	5.25e-90	304.0	COG2823@1|root,COG2823@2|Bacteria,1N42J@1224|Proteobacteria,2VK5B@28216|Betaproteobacteria,4AHC6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	BON,Cytidylate_kin2
PYH2_k127_5860631_1	1458275.AZ34_11045	4.124e-273	847.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,4AAW5@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
PYH2_k127_5860631_18	543728.Vapar_4492	2.947e-53	201.0	2BKYI@1|root,32FF5@2|Bacteria,1MY1A@1224|Proteobacteria,2VRUQ@28216|Betaproteobacteria,4AERJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
PYH2_k127_5860631_9	864051.BurJ1DRAFT_3669	4.525e-167	531.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VKSV@28216|Betaproteobacteria,1KN7P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_5860631_11	864051.BurJ1DRAFT_3671	1.919e-93	320.0	COG2199@1|root,COG2199@2|Bacteria,1R1VQ@1224|Proteobacteria,2VPRA@28216|Betaproteobacteria,1KKEC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
PYH2_k127_5860631_5	748247.AZKH_2527	1.715e-184	582.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VJ9X@28216|Betaproteobacteria	28216|Betaproteobacteria	CE	Tartrate dehydrogenase	-	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
PYH2_k127_5860631_7	1265502.KB905931_gene1685	2.322e-182	579.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VH8N@28216|Betaproteobacteria,4AAGJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
PYH2_k127_5860631_20	983917.RGE_15280	8.283e-35	134.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,1KM8X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
PYH2_k127_5860631_17	1265502.KB905931_gene1683	1.828e-59	209.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,4ADG9@80864|Comamonadaceae	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
PYH2_k127_5860631_19	1265502.KB905931_gene1682	1.05e-40	154.0	COG3453@1|root,COG3453@2|Bacteria,1N9AF@1224|Proteobacteria,2VU0V@28216|Betaproteobacteria,4AIBJ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
PYH2_k127_5860631_14	395495.Lcho_1781	1.382e-78	269.0	COG4665@1|root,COG4665@2|Bacteria,1RHBW@1224|Proteobacteria,2VRCB@28216|Betaproteobacteria,1KKVD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Tripartite ATP-independent periplasmic transporter DctQ	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH2_k127_5860631_3	395495.Lcho_1780	1.439e-219	687.0	COG4664@1|root,COG4664@2|Bacteria,1R4MZ@1224|Proteobacteria,2VHHD@28216|Betaproteobacteria,1KJ5Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	TRAP dicarboxylate transporter, DctM subunit	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	DctM
PYH2_k127_58716_3	94624.Bpet1147	6.464e-36	144.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,2VH6U@28216|Betaproteobacteria,3T870@506|Alcaligenaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve
PYH2_k127_58716_2	935567.JAES01000020_gene574	1.584e-66	235.0	COG3795@1|root,COG3795@2|Bacteria,1RCZT@1224|Proteobacteria,1S69N@1236|Gammaproteobacteria,1X6M5@135614|Xanthomonadales	135614|Xanthomonadales	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
PYH2_k127_58716_4	1458357.BG58_19285	1.815e-12	71.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,2VKYD@28216|Betaproteobacteria,1K58P@119060|Burkholderiaceae	28216|Betaproteobacteria	K	RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
PYH2_k127_58716_1	987059.RBXJA2T_04253	1.712e-79	275.0	28I7A@1|root,2Z8A6@2|Bacteria,1NNDP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_58716_0	395495.Lcho_3544	5.901e-151	489.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VMMZ@28216|Betaproteobacteria,1KMB6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	pleD	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
PYH2_k127_58716_5	395495.Lcho_3543	6.57e-11	67.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3829@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,1KJCZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
PYH2_k127_5871868_10	420662.Mpe_A3527	1.453e-15	82.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,2VK1C@28216|Betaproteobacteria,1KKI4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH2_k127_5871868_9	889378.Spiaf_0930	5.189e-22	98.0	COG2110@1|root,COG2110@2|Bacteria,2J6ZA@203691|Spirochaetes	203691|Spirochaetes	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
PYH2_k127_5871868_11	279714.FuraDRAFT_3037	2.488e-14	79.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria,2KR3W@206351|Neisseriales	206351|Neisseriales	S	Macro domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
PYH2_k127_5871868_1	1265502.KB905951_gene844	2.67e-163	520.0	COG0715@1|root,COG0715@2|Bacteria,1MVZE@1224|Proteobacteria,2VJ88@28216|Betaproteobacteria,4A9W3@80864|Comamonadaceae	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
PYH2_k127_5871868_4	1265502.KB905951_gene843	4.417e-132	430.0	COG1116@1|root,COG1116@2|Bacteria,1N7FP@1224|Proteobacteria,2VHGX@28216|Betaproteobacteria,4ACTB@80864|Comamonadaceae	28216|Betaproteobacteria	P	SMART AAA ATPase	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PYH2_k127_5871868_2	1265502.KB905951_gene842	2.027e-146	469.0	COG0600@1|root,COG0600@2|Bacteria,1MVD2@1224|Proteobacteria,2VI9N@28216|Betaproteobacteria,4AC9H@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PYH2_k127_5871868_5	298654.FraEuI1c_4557	1.428e-58	227.0	2DMP1@1|root,32SS8@2|Bacteria,2IMQ1@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0311 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
PYH2_k127_5871868_0	420662.Mpe_A3524	8.591e-294	906.0	COG1012@1|root,COG1012@2|Bacteria,1MUHV@1224|Proteobacteria,2VI0N@28216|Betaproteobacteria,1KK5P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	methylmalonate-semialdehyde dehydrogenase	mmsA_2	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_5871868_7	1441930.Z042_14460	2.294e-53	199.0	COG1309@1|root,COG1309@2|Bacteria,1N11B@1224|Proteobacteria,1S8PU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PYH2_k127_5871868_3	1223521.BBJX01000001_gene1020	8.923e-139	454.0	COG0778@1|root,COG0778@2|Bacteria,1NTK9@1224|Proteobacteria,2VYQ2@28216|Betaproteobacteria,4AGFC@80864|Comamonadaceae	28216|Betaproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
PYH2_k127_5871868_6	983917.RGE_01130	1.433e-57	209.0	COG3318@1|root,COG3318@2|Bacteria,1QF7R@1224|Proteobacteria,2VP9G@28216|Betaproteobacteria,1KJUA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0149)	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	SEC-C,UPF0149
PYH2_k127_5871868_8	420662.Mpe_A3516	7.026e-34	136.0	COG3540@1|root,COG3540@2|Bacteria,1MWAF@1224|Proteobacteria,2VKX4@28216|Betaproteobacteria,1KJ03@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD2	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
PYH2_k127_5873182_0	1157708.KB907450_gene5757	0.0	1605.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VHCG@28216|Betaproteobacteria,4ABUZ@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
PYH2_k127_589035_2	1408164.MOLA814_01776	4.795e-173	580.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VH9Y@28216|Betaproteobacteria	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_589035_0	296591.Bpro_3015	2.436e-195	638.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VHMS@28216|Betaproteobacteria,4ABPG@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_589035_1	358220.C380_03360	6.296e-192	610.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,4AAB0@80864|Comamonadaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB2	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH2_k127_5901600_3	543728.Vapar_3449	4.469e-50	183.0	COG3172@1|root,COG3172@2|Bacteria,1RI98@1224|Proteobacteria,2VSFE@28216|Betaproteobacteria,4AESQ@80864|Comamonadaceae	28216|Betaproteobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
PYH2_k127_5901600_5	661478.OP10G_0345	7.252e-21	97.0	2EMQ2@1|root,33FCI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5901600_2	159087.Daro_3438	4.883e-59	209.0	COG3324@1|root,COG3324@2|Bacteria,1N1P5@1224|Proteobacteria,2W3PV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
PYH2_k127_5901600_1	987059.RBXJA2T_12377	1.488e-74	257.0	COG3201@1|root,COG3201@2|Bacteria,1MXN4@1224|Proteobacteria,2VRT2@28216|Betaproteobacteria,1KKZ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Nicotinamide mononucleotide transporter	pnuC	-	-	ko:K03811	-	-	-	-	ko00000,ko02000	4.B.1.1	-	-	NMN_transporter
PYH2_k127_5901600_4	1265502.KB905931_gene1665	8.252e-30	120.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,4AFFP@80864|Comamonadaceae	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
PYH2_k127_5901600_0	365046.Rta_25820	1.579e-79	266.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,4A9T6@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PYH2_k127_5904396_6	420662.Mpe_A1972	1.207e-94	322.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,1KJM6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	zinc metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
PYH2_k127_5904396_0	395495.Lcho_2844	2.138e-168	540.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,1KJI9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
PYH2_k127_5904396_5	395495.Lcho_2845	5.311e-96	324.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,1KJZN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
PYH2_k127_5904396_4	864051.BurJ1DRAFT_2931	2.851e-122	395.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,1KIUJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
PYH2_k127_5904396_7	1265502.KB905935_gene3045	7.473e-89	303.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,4ABF3@80864|Comamonadaceae	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
PYH2_k127_5904396_2	864051.BurJ1DRAFT_2933	2.165e-133	431.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,1KJU7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PYH2_k127_5904396_3	987059.RBXJA2T_18006	2.389e-133	433.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,1KJ30@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
PYH2_k127_5904396_1	987059.RBXJA2T_18001	1.257e-134	431.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,1KJMP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
PYH2_k127_5904396_8	983917.RGE_27400	8.982e-14	75.0	COG0154@1|root,COG0154@2|Bacteria,1MU51@1224|Proteobacteria,2VJN4@28216|Betaproteobacteria,1KK89@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Amidase	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH2_k127_5946886_11	614083.AWQR01000007_gene353	0.0002758	45.0	2DBRJ@1|root,2ZAMD@2|Bacteria,1R498@1224|Proteobacteria,2VMV1@28216|Betaproteobacteria,4ACAB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
PYH2_k127_5946886_0	614083.AWQR01000007_gene354	7.499e-255	807.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,2WGER@28216|Betaproteobacteria,4AD7W@80864|Comamonadaceae	28216|Betaproteobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
PYH2_k127_5946886_9	420662.Mpe_A1564	2.907e-87	293.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria,1KKKC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	DSBA oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
PYH2_k127_5946886_4	1100720.ALKN01000033_gene732	1.285e-140	452.0	COG4177@1|root,COG4177@2|Bacteria,1MWP3@1224|Proteobacteria,2VJA3@28216|Betaproteobacteria,4ABMN@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_5946886_2	1100720.ALKN01000033_gene731	1.207e-154	492.0	COG0559@1|root,COG0559@2|Bacteria,1MY1E@1224|Proteobacteria,2VIR5@28216|Betaproteobacteria,4A9SI@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_5946886_1	1100720.ALKN01000033_gene730	7.963e-200	629.0	COG0683@1|root,COG0683@2|Bacteria,1MUCB@1224|Proteobacteria,2VHXC@28216|Betaproteobacteria,4AB9R@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_5946886_7	296591.Bpro_4076	6.791e-111	363.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2VJA0@28216|Betaproteobacteria,4ABV2@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_5946886_5	264198.Reut_A3371	2.531e-129	417.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VJN5@28216|Betaproteobacteria,1K0H1@119060|Burkholderiaceae	28216|Betaproteobacteria	E	abc transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_5946886_10	1265502.KB905929_gene2224	1.341e-15	83.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,4AG0G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5946886_6	1205680.CAKO01000038_gene1996	4.082e-117	385.0	COG2175@1|root,COG2175@2|Bacteria,1MV5K@1224|Proteobacteria,2TQTZ@28211|Alphaproteobacteria,2JSGW@204441|Rhodospirillales	204441|Rhodospirillales	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	ko:K22303	-	-	-	-	ko00000,ko01000	-	-	-	TauD
PYH2_k127_5946886_8	395495.Lcho_0012	8.648e-100	335.0	COG0767@1|root,COG0767@2|Bacteria,1NSBS@1224|Proteobacteria,2VKK9@28216|Betaproteobacteria,1KN8P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
PYH2_k127_5946886_3	395495.Lcho_0011	5.142e-148	483.0	COG1463@1|root,COG1463@2|Bacteria,1R565@1224|Proteobacteria,2VK63@28216|Betaproteobacteria,1KN9M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
PYH2_k127_5947467_1	177439.DPPB38	5.535e-138	445.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2WJ1R@28221|Deltaproteobacteria,2MMYC@213118|Desulfobacterales	28221|Deltaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
PYH2_k127_5947467_0	930171.Asphe3_00700	6.71e-145	475.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria	201174|Actinobacteria	C	Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
PYH2_k127_5947467_2	468059.AUHA01000003_gene1722	1.02e-21	109.0	COG0508@1|root,COG0508@2|Bacteria,4NE41@976|Bacteroidetes,1IVKR@117747|Sphingobacteriia	976|Bacteroidetes	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH2_k127_5977153_1	864051.BurJ1DRAFT_2867	1.168e-122	398.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,1KJ1H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
PYH2_k127_5977153_2	1265502.KB905929_gene2292	1.452e-92	310.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,4AAHT@80864|Comamonadaceae	28216|Betaproteobacteria	O	Methyltransferase type 11	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
PYH2_k127_5977153_0	420662.Mpe_A1041	1.012e-148	487.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,1KK6Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC family	tolC	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
PYH2_k127_5977153_3	1380391.JIAS01000014_gene2149	5.001e-87	304.0	COG5267@1|root,COG5267@2|Bacteria,1MWJK@1224|Proteobacteria,2TSY7@28211|Alphaproteobacteria,2JQ8U@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
PYH2_k127_5980304_1	296591.Bpro_0639	2.599e-235	732.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2VJUW@28216|Betaproteobacteria,4ABFK@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	cobZ	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
PYH2_k127_5980304_2	279714.FuraDRAFT_2544	1.26e-176	561.0	COG1146@1|root,COG1146@2|Bacteria,1MU2I@1224|Proteobacteria,2VJHI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CitB domain protein	citB	-	-	ko:K13795	-	-	-	-	ko00000	-	-	-	-
PYH2_k127_5980304_3	420662.Mpe_A2495	1.107e-148	482.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,1KK2P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
PYH2_k127_5980304_5	1538295.JY96_00810	1.807e-40	156.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,1KJ6Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_7,PAS_8,PAS_9,PilJ,Response_reg
PYH2_k127_5980304_4	864051.BurJ1DRAFT_2898	4.713e-130	422.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,1KJIW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc
PYH2_k127_5980304_0	864051.BurJ1DRAFT_2897	0.0	1152.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,1KJFB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
PYH2_k127_5983341_0	420662.Mpe_A3359	9.439e-206	643.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,1KJ65@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxyl transferase domain	accB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
PYH2_k127_5983341_2	1123504.JQKD01000002_gene3714	1.061e-75	258.0	COG2318@1|root,COG2318@2|Bacteria,1RD3M@1224|Proteobacteria,2VRXA@28216|Betaproteobacteria,4ADY9@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM DinB family protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB
PYH2_k127_5983341_1	864051.BurJ1DRAFT_4740	1.962e-122	404.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,1KJZJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.18	ko:K13766,ko:K15312	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	ECH_1
PYH2_k127_5983341_3	420662.Mpe_A3357	9.153e-47	179.0	28JRZ@1|root,2Z9HI@2|Bacteria,1R52Z@1224|Proteobacteria,2VRVF@28216|Betaproteobacteria,1KKSB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
PYH2_k127_5983849_4	314287.GB2207_04817	8.083e-31	130.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,1J4T5@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_11,TPR_16,TPR_19,TPR_8
PYH2_k127_5983849_3	1487953.JMKF01000059_gene4891	2.022e-32	142.0	2DBXS@1|root,2ZBR1@2|Bacteria,1G9A8@1117|Cyanobacteria,1HFXF@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5983849_2	387093.SUN_0406	1.73e-59	223.0	COG4461@1|root,COG4461@2|Bacteria,1PFFH@1224|Proteobacteria,43ABM@68525|delta/epsilon subdivisions,2YR0C@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
PYH2_k127_5983849_0	1123519.PSJM300_04655	4.046e-151	496.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,1RMIF@1236|Gammaproteobacteria,1Z1W2@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	I	COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	clsC	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PYH2_k127_5983849_6	420662.Mpe_A3091	1.073e-18	90.0	COG4520@1|root,COG4520@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	17kDa_Anti_2,SH3_3
PYH2_k127_5983849_5	522306.CAP2UW1_0134	1.561e-23	106.0	2CHK6@1|root,333A9@2|Bacteria,1N9I7@1224|Proteobacteria,2VWH1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5983849_1	1232410.KI421426_gene1482	4.418e-65	224.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2WKQV@28221|Deltaproteobacteria,43V5R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
PYH2_k127_5984214_0	987059.RBXJA2T_04503	0.0	2577.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VI87@28216|Betaproteobacteria,1KJJ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA2	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
PYH2_k127_5984214_1	864073.HFRIS_017397	4.683e-26	110.0	COG0590@1|root,COG0590@2|Bacteria,1RHM4@1224|Proteobacteria,2VQ13@28216|Betaproteobacteria,4773A@75682|Oxalobacteraceae	28216|Betaproteobacteria	FJ	Guanine deaminase (Guanase) (Guanine aminase) (Guanine aminohydrolase) (GAH) (GDEase)	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
PYH2_k127_5988065_1	1300345.LF41_902	1.516e-46	179.0	COG2067@1|root,COG2067@2|Bacteria,1RJIQ@1224|Proteobacteria,1SAC1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5988065_2	338966.Ppro_1433	2.443e-06	50.0	COG2930@1|root,COG2930@2|Bacteria,1RAIB@1224|Proteobacteria,42S9D@68525|delta/epsilon subdivisions,2X2H8@28221|Deltaproteobacteria,43VFB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
PYH2_k127_5988065_0	640511.BC1002_5549	1.715e-93	317.0	COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,2WI17@28216|Betaproteobacteria,1KG8X@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
PYH2_k127_5994696_3	909663.KI867150_gene2800	1.645e-187	597.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria,2MQYI@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Carbohydrate phosphorylase	-	-	2.4.1.1,2.4.1.11	ko:K00688,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R00292,R02111	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT3,GT35	-	DUF3417,Phosphorylase
PYH2_k127_5994696_0	1123392.AQWL01000007_gene1019	0.0	1306.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,1KSK1@119069|Hydrogenophilales	119069|Hydrogenophilales	G	XFP C-terminal domain	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
PYH2_k127_5994696_1	395495.Lcho_3847	2.314e-284	882.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,1KIZA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
PYH2_k127_5994696_5	395495.Lcho_3846	9.286e-16	83.0	2EJUE@1|root,33DJ2@2|Bacteria,1NJVX@1224|Proteobacteria,2VY2W@28216|Betaproteobacteria,1KMQ6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_5994696_2	395495.Lcho_1925	8.831e-229	718.0	COG2918@1|root,COG2918@2|Bacteria,1MW9B@1224|Proteobacteria,2VKVU@28216|Betaproteobacteria,1KK05@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	Glu_cys_ligase
PYH2_k127_5994696_6	62928.azo3127	2.99e-08	62.0	2DZ51@1|root,34CFR@2|Bacteria,1P4XD@1224|Proteobacteria,2W5BH@28216|Betaproteobacteria,2KZF2@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
PYH2_k127_6004809_2	67356.KL575625_gene877	1.071e-11	69.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
PYH2_k127_6004809_5	1040989.AWZU01000127_gene1263	1.904e-07	64.0	COG3710@1|root,COG3710@2|Bacteria	2|Bacteria	K	Transcriptional regulator	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Trans_reg_C
PYH2_k127_6004809_0	161528.ED21_25988	1.097e-64	244.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1N7YB@1224|Proteobacteria,2V7CZ@28211|Alphaproteobacteria,2K2SU@204457|Sphingomonadales	204457|Sphingomonadales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
PYH2_k127_6004809_3	296591.Bpro_1379	4.438e-11	72.0	COG2771@1|root,COG2771@2|Bacteria,1MWC0@1224|Proteobacteria,2VX4W@28216|Betaproteobacteria,4AFSX@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PYH2_k127_6004809_4	1502851.FG93_05281	3.584e-10	64.0	COG2771@1|root,COG2771@2|Bacteria,1MWC0@1224|Proteobacteria,2U1YZ@28211|Alphaproteobacteria,3K716@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PYH2_k127_6004809_1	261292.Nit79A3_3314	1.124e-44	171.0	COG5549@1|root,COG5549@2|Bacteria,1PE84@1224|Proteobacteria,2WC16@28216|Betaproteobacteria,37458@32003|Nitrosomonadales	28216|Betaproteobacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_600573_22	864051.BurJ1DRAFT_2418	1.132e-29	120.0	COG0725@1|root,COG0725@2|Bacteria,1NY9R@1224|Proteobacteria,2VRYF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
PYH2_k127_600573_13	1276756.AUEX01000004_gene2353	1.069e-91	311.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_600573_4	375286.mma_0818	9.016e-163	518.0	COG2267@1|root,COG2267@2|Bacteria,1MV7P@1224|Proteobacteria,2VPTY@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
PYH2_k127_600573_10	1349767.GJA_818	1.022e-110	374.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2VIR2@28216|Betaproteobacteria,473W0@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Coenzyme A transferase	pcaI	-	2.8.3.6	ko:K01031	ko00362,ko01100,ko01120,map00362,map01100,map01120	-	R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH2_k127_600573_11	1265502.KB905934_gene3250	2.31e-107	354.0	COG2057@1|root,COG2057@2|Bacteria,1MWW1@1224|Proteobacteria,2VIBE@28216|Betaproteobacteria,4ABU9@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Coenzyme A transferase	pcaJ	-	2.8.3.6	ko:K01032	ko00362,ko01100,ko01120,map00362,map01100,map01120	-	R02990	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH2_k127_600573_12	420662.Mpe_A2889	8.575e-105	347.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,1KJM5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the pirin family	yhhW_2	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
PYH2_k127_600573_6	1218084.BBJK01000078_gene5422	7.233e-151	490.0	COG0665@1|root,COG0665@2|Bacteria,1MVGP@1224|Proteobacteria,2VIFN@28216|Betaproteobacteria,1K00B@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM FAD dependent oxidoreductase	-	-	-	ko:K09471	ko00330,ko01100,map00330,map01100	M00136	R07415	RC00062	ko00000,ko00001,ko00002,ko01000	-	-	-	DAO
PYH2_k127_600573_5	1042876.PPS_0528	2.783e-154	494.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,1RN24@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	L-2-hydroxyglutarate oxidase LhgO	-	-	-	-	-	-	-	-	-	-	-	-	DAO
PYH2_k127_600573_2	1265502.KB905938_gene2458	3.411e-209	663.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,2W3XP@28216|Betaproteobacteria,4AK16@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
PYH2_k127_600573_1	420662.Mpe_A3163	3.028e-213	666.0	COG2170@1|root,COG2170@2|Bacteria,1MX4N@1224|Proteobacteria,2VK27@28216|Betaproteobacteria,1KK9H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity	ybdK	-	-	ko:K06048	-	-	-	-	ko00000,ko01000	-	-	-	GCS2
PYH2_k127_600573_7	420662.Mpe_A3162	1.431e-136	449.0	COG0475@1|root,COG0475@2|Bacteria,1R9PF@1224|Proteobacteria,2VKV2@28216|Betaproteobacteria,1KKRF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
PYH2_k127_600573_3	864051.BurJ1DRAFT_1682	1.286e-188	596.0	COG1840@1|root,COG1840@2|Bacteria,1MXZ8@1224|Proteobacteria,2VKTZ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6
PYH2_k127_600573_0	987059.RBXJA2T_14451	0.0	1045.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,1KJN9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
PYH2_k127_600573_9	864051.BurJ1DRAFT_1062	1.132e-130	425.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,1KK3E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
PYH2_k127_600573_15	864051.BurJ1DRAFT_1063	5.213e-82	281.0	2C9ES@1|root,32HUV@2|Bacteria,1RKUI@1224|Proteobacteria,2VSTQ@28216|Betaproteobacteria,1KM4N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726
PYH2_k127_600573_19	1265502.KB905945_gene612	1.702e-70	250.0	COG0454@1|root,COG0456@2|Bacteria,1QUZC@1224|Proteobacteria,2WGMV@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_3
PYH2_k127_600573_16	864051.BurJ1DRAFT_1065	6.045e-80	270.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,1KKPH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
PYH2_k127_600573_18	864051.BurJ1DRAFT_1066	4.472e-71	242.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,1KKPA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
PYH2_k127_600573_14	864051.BurJ1DRAFT_1067	2.492e-86	293.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria,1KKMJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_600573_21	864051.BurJ1DRAFT_1068	7.281e-54	192.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,1KM73@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
PYH2_k127_600573_20	864051.BurJ1DRAFT_1069	3.042e-63	218.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,1KKSP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
PYH2_k127_600573_8	420662.Mpe_A3152	1.042e-132	436.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria,1KKAK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
PYH2_k127_600573_17	1286631.X805_33530	1.422e-71	246.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,1KIVP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
PYH2_k127_6033083_0	987059.RBXJA2T_02587	5.974e-166	530.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,1KJDF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
PYH2_k127_6033083_2	420662.Mpe_A0273	1.223e-59	212.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,1KM6N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
PYH2_k127_6033083_1	1265502.KB905952_gene811	9.73e-63	223.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,4A9SK@80864|Comamonadaceae	28216|Betaproteobacteria	T	Signal transduction histidine kinase	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
PYH2_k127_6055122_2	543728.Vapar_5477	2.37e-180	571.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria,4ACNH@80864|Comamonadaceae	28216|Betaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH2_k127_6055122_0	1157708.KB907453_gene4250	0.0	1011.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2VIEB@28216|Betaproteobacteria,4A9VY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
PYH2_k127_6055122_1	595537.Varpa_2455	9.054e-266	824.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,4AD4V@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	korC	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_7,Pyr_redox_2,Pyr_redox_3
PYH2_k127_6066970_0	483219.LILAB_15690	7.293e-105	376.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
PYH2_k127_6066970_1	313603.FB2170_10516	1.776e-09	65.0	2DPHC@1|root,32UM4@2|Bacteria,4NT51@976|Bacteroidetes,1I4TT@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6066970_2	1301098.PKB_4072	2.09e-05	51.0	COG0596@1|root,COG0596@2|Bacteria,1RDP1@1224|Proteobacteria,1S67D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1
PYH2_k127_6071229_1	1123073.KB899241_gene2886	2.338e-98	332.0	2DNAS@1|root,32WH6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phi_1
PYH2_k127_6071229_0	626418.bglu_1g32540	0.0	1478.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VN0R@28216|Betaproteobacteria,1K2NT@119060|Burkholderiaceae	28216|Betaproteobacteria	C	oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
PYH2_k127_6084357_1	497321.C664_18579	1.172e-250	779.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,2KVI2@206389|Rhodocyclales	206389|Rhodocyclales	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
PYH2_k127_6084357_7	1144275.COCOR_08075	1.47e-25	117.0	COG0346@1|root,COG0346@2|Bacteria,1RGVH@1224|Proteobacteria	1224|Proteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	yycE	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Glyoxalase
PYH2_k127_6084357_4	1286631.X805_14180	1.047e-103	343.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,2VK8J@28216|Betaproteobacteria,1KJRS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
PYH2_k127_6084357_2	420662.Mpe_A3288	9.018e-155	496.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,1KJJJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
PYH2_k127_6084357_5	983917.RGE_04950	6.158e-97	321.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,2VJZE@28216|Betaproteobacteria,1KK6Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	5-formyltetrahydrofolate cyclo-ligase	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
PYH2_k127_6084357_6	395495.Lcho_0114	1.559e-32	134.0	COG3070@1|root,COG3070@2|Bacteria,1N8X8@1224|Proteobacteria,2VVUD@28216|Betaproteobacteria,1KMNK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	TfoX N-terminal domain	tfoX	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
PYH2_k127_6084357_9	420662.Mpe_A3293	7.877e-10	64.0	2EPBS@1|root,33GYH@2|Bacteria,1NMAQ@1224|Proteobacteria,2VZ11@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2917)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2917
PYH2_k127_6084357_3	987059.RBXJA2T_17821	1.299e-122	400.0	COG0583@1|root,COG0583@2|Bacteria,1MWY0@1224|Proteobacteria,2VIST@28216|Betaproteobacteria,1KJK6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR family	-	-	-	ko:K03566	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_6084357_0	420662.Mpe_A3295	4.468e-259	815.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,1KJ7Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lytic transglycosylase catalytic	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
PYH2_k127_6084357_8	987059.RBXJA2T_17831	1.126e-24	109.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,1KJ0U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
PYH2_k127_6087245_1	365044.Pnap_1238	9.987e-112	372.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,1NTIV@1224|Proteobacteria,2VKDX@28216|Betaproteobacteria,4ACW5@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Fibronectin type III domain protein	phaZ	-	3.1.1.75	ko:K05973	ko00650,map00650	-	R05118	-	ko00000,ko00001,ko01000	-	-	-	Esterase_phd,fn3
PYH2_k127_6087245_0	977880.RALTA_A1802	3.069e-158	500.0	COG0683@1|root,COG0683@2|Bacteria,1N1MX@1224|Proteobacteria,2VJMT@28216|Betaproteobacteria,1KGRT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	amino acid	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_6087318_1	388051.AUFE01000043_gene3294	9.965e-164	520.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria,1K556@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NADH dehydrogenase	hyfD	-	-	-	-	-	-	-	-	-	-	-	NADHdh
PYH2_k127_6087318_2	296591.Bpro_0918	6.045e-100	346.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria,4AC7I@80864|Comamonadaceae	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
PYH2_k127_6087318_0	1366050.N234_08435	3.768e-278	860.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria,1K2R7@119060|Burkholderiaceae	28216|Betaproteobacteria	CP	Proton-conducting membrane transporter	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
PYH2_k127_6087318_3	381666.H16_A2200	1.352e-09	61.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria,1K61J@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
PYH2_k127_6088534_1	518766.Rmar_1606	2.628e-78	274.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
PYH2_k127_6088534_0	1211115.ALIQ01000108_gene1209	3.081e-104	378.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,3NAFU@45404|Beijerinckiaceae	28211|Alphaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
PYH2_k127_6088534_2	1452718.JBOY01000105_gene425	2.704e-72	253.0	COG0745@1|root,COG0745@2|Bacteria,1MY3D@1224|Proteobacteria,1RPKN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PYH2_k127_6088534_4	1163617.SCD_n01425	1.864e-05	51.0	2CM31@1|root,32SD0@2|Bacteria,1N2TZ@1224|Proteobacteria,2VUNK@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_61365_2	292415.Tbd_1586	6.2e-48	176.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
PYH2_k127_61365_1	580332.Slit_1846	2.252e-176	563.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
PYH2_k127_61365_3	935567.JAES01000004_gene134	1.644e-43	167.0	2BWJV@1|root,32U7J@2|Bacteria,1N47S@1224|Proteobacteria,1S8XJ@1236|Gammaproteobacteria,1X7VT@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_61365_0	420662.Mpe_A2083	5.543e-212	670.0	COG2186@1|root,COG2186@2|Bacteria,1QZYM@1224|Proteobacteria,2VI66@28216|Betaproteobacteria,1KJZ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Domain of unknown function (DUF5117)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4953,DUF5117,DUF5118
PYH2_k127_6173020_1	543728.Vapar_3996	2.42e-169	535.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI98@28216|Betaproteobacteria,4AAQC@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PYH2_k127_6173020_2	189753.AXAS01000041_gene2534	1.088e-63	231.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_6173020_3	420324.KI912071_gene8169	5.495e-47	182.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,1JUDJ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_6173020_4	864051.BurJ1DRAFT_3207	5.495e-05	48.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,2VQRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
PYH2_k127_6173020_0	264198.Reut_B4712	4.763e-297	917.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VNB8@28216|Betaproteobacteria,1KGH9@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
PYH2_k127_6267838_1	1123248.KB893370_gene5116	2.431e-67	239.0	COG2084@1|root,COG2084@2|Bacteria	2|Bacteria	I	phosphogluconate dehydrogenase (decarboxylating) activity	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
PYH2_k127_6267838_0	161528.ED21_25988	8.418e-73	269.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1N7YB@1224|Proteobacteria,2V7CZ@28211|Alphaproteobacteria,2K2SU@204457|Sphingomonadales	204457|Sphingomonadales	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
PYH2_k127_6267838_2	1429851.X548_20120	2.037e-18	100.0	COG0457@1|root,COG2114@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,1P8ZU@1224|Proteobacteria,1S6BW@1236|Gammaproteobacteria,1X4FC@135614|Xanthomonadales	135614|Xanthomonadales	T	Pfam Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_19
PYH2_k127_6276960_8	983917.RGE_13200	1.607e-47	192.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VIVH@28216|Betaproteobacteria,1KJKC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
PYH2_k127_6276960_4	864051.BurJ1DRAFT_3738	6.118e-167	538.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,1KKCI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	NMT1-like family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
PYH2_k127_6276960_6	522306.CAP2UW1_2358	1.119e-111	370.0	COG4188@1|root,COG4188@2|Bacteria,1R9J5@1224|Proteobacteria	1224|Proteobacteria	S	Platelet-activating factor acetylhydrolase plasma intracellular isoform II	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,PAF-AH_p_II
PYH2_k127_6276960_5	296591.Bpro_3590	7.246e-157	497.0	COG3483@1|root,COG3483@2|Bacteria,1MW68@1224|Proteobacteria,2VJG3@28216|Betaproteobacteria,4ACUT@80864|Comamonadaceae	28216|Betaproteobacteria	E	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety	kynA	GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	1.13.11.11	ko:K00453	ko00380,ko01100,map00380,map01100	M00038	R00678	RC00356	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_dioxygenase
PYH2_k127_6276960_1	1265502.KB905934_gene3236	3.516e-207	653.0	COG3844@1|root,COG3844@2|Bacteria,1MUKN@1224|Proteobacteria,2VIP0@28216|Betaproteobacteria,4AAXE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively	kynU	-	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
PYH2_k127_6276960_7	358220.C380_18715	6.781e-96	323.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,2VHG4@28216|Betaproteobacteria,4ABNH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation	kynB	GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
PYH2_k127_6276960_9	1286631.X805_07110	6.167e-45	166.0	COG0727@1|root,COG0727@2|Bacteria,1N027@1224|Proteobacteria,2VU3Y@28216|Betaproteobacteria,1KMDH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
PYH2_k127_6276960_3	983917.RGE_13320	2.24e-179	578.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,1KJGX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
PYH2_k127_6276960_2	420662.Mpe_A3029	1.114e-206	654.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,1KJFK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	acetylornithine	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_6276960_11	864051.BurJ1DRAFT_3109	2.244e-27	117.0	COG0454@1|root,COG0456@2|Bacteria,1N7JM@1224|Proteobacteria,2VU1F@28216|Betaproteobacteria,1KM0F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
PYH2_k127_6276960_10	864051.BurJ1DRAFT_3108	6.177e-40	153.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,1KMD3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
PYH2_k127_6276960_0	420662.Mpe_A3026	1.916e-208	658.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,1KK6B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
PYH2_k127_629568_1	1458357.BG58_40735	2.821e-74	251.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2VQ3M@28216|Betaproteobacteria,1KGKC@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	KR domain	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
PYH2_k127_629568_0	1265502.KB905930_gene1543	2.7e-141	464.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKRZ@28216|Betaproteobacteria,4AAEX@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.18	ko:K00822	ko00280,ko00410,ko00640,ko01100,map00280,map00410,map00640,map01100	-	R00907,R04187	RC00008,RC00062,RC00160	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_6314408_7	709797.CSIRO_3921	1.574e-28	122.0	COG0683@1|root,COG0683@2|Bacteria,1MWH7@1224|Proteobacteria,2TS8K@28211|Alphaproteobacteria,3JUFA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_6314408_0	864051.BurJ1DRAFT_2265	1.962e-317	986.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VGZE@28216|Betaproteobacteria,1KIY7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	alkK	-	6.2.1.44	ko:K20034	ko00920,map00920	-	R10820	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_6314408_8	983917.RGE_24310	3.959e-24	115.0	COG0397@1|root,COG0397@2|Bacteria,1MVK3@1224|Proteobacteria,2VH7S@28216|Betaproteobacteria,1KIV6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0061 (SELO) family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0061
PYH2_k127_6314408_6	1265502.KB905940_gene3007	1.258e-60	220.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,4AE0C@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
PYH2_k127_6314408_4	420662.Mpe_A1766	4.536e-85	286.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,1KKPT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
PYH2_k127_6314408_9	987059.RBXJA2T_08940	2.836e-22	106.0	COG0271@1|root,COG0271@2|Bacteria,1MZG5@1224|Proteobacteria,2VVNP@28216|Betaproteobacteria,1KMJC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Belongs to the BolA IbaG family	bolA	-	-	ko:K05527	-	-	-	-	ko00000,ko03000	-	-	-	BolA
PYH2_k127_6314408_2	1538295.JY96_19865	1.495e-102	346.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,1KJ83@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	peptidylprolyl isomerase	cbf2	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N_3
PYH2_k127_6314408_3	420662.Mpe_A1816	2.258e-102	336.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,1KIVG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	ATPases associated with a variety of cellular activities	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_6314408_5	864051.BurJ1DRAFT_2260	8.199e-84	290.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2VRIQ@28216|Betaproteobacteria,1KKPU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
PYH2_k127_6314408_1	296591.Bpro_3196	1.911e-196	614.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,2VMDX@28216|Betaproteobacteria,4ADVR@80864|Comamonadaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
PYH2_k127_6320692_1	94624.Bpet3944	1.21e-90	301.0	COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,2VJVQ@28216|Betaproteobacteria,3T3DY@506|Alcaligenaceae	28216|Betaproteobacteria	IQ	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases	-	-	-	ko:K18335	ko00051,ko01120,map00051,map01120	-	R10690	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
PYH2_k127_6320692_0	1532557.JL37_19835	8.65e-154	489.0	COG0179@1|root,COG0179@2|Bacteria,1MUPF@1224|Proteobacteria,2VI5Z@28216|Betaproteobacteria,3T1ZZ@506|Alcaligenaceae	28216|Betaproteobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-17-dioic acid hydratase (catechol pathway)	-	-	-	ko:K18336	ko00051,ko01120,map00051,map01120	-	R10691	RC00326,RC03236	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
PYH2_k127_6320692_2	864051.BurJ1DRAFT_3909	3.049e-41	156.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VHJB@28216|Betaproteobacteria,1KJ14@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	D-galactarate dehydratase Altronate hydrolase	uxaA	-	4.2.1.7,4.4.1.24	ko:K01685,ko:K16846	ko00040,ko00270,ko01100,map00040,map00270,map01100	M00631	R01540,R07633	RC00543,RC01785	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
PYH2_k127_6351967_3	316057.RPD_1523	3.556e-50	183.0	COG1319@1|root,COG1319@2|Bacteria,1MVJS@1224|Proteobacteria,2TRAR@28211|Alphaproteobacteria,3JR53@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	MA20_09760	-	1.17.1.4,1.3.7.9	ko:K04109,ko:K11178	ko00230,ko00362,ko00627,ko01100,ko01120,ko01220,map00230,map00362,map00627,map01100,map01120,map01220	M00546	R01768,R02103,R05316	RC00143,RC00490	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH2_k127_6351967_5	1238182.C882_1438	1.364e-18	93.0	2E0AX@1|root,32VY8@2|Bacteria,1N21Q@1224|Proteobacteria,2UECC@28211|Alphaproteobacteria,2JTNW@204441|Rhodospirillales	204441|Rhodospirillales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
PYH2_k127_6351967_2	1244869.H261_21688	1.256e-69	248.0	COG0454@1|root,COG0456@2|Bacteria,1RGZ2@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PYH2_k127_6351967_4	1163617.SCD_n00448	3.967e-29	127.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VUA0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
PYH2_k127_6351967_1	640081.Dsui_0624	1.441e-103	351.0	COG4243@1|root,COG4243@2|Bacteria,1MW9C@1224|Proteobacteria,2VPG2@28216|Betaproteobacteria,2KU9P@206389|Rhodocyclales	206389|Rhodocyclales	S	Vitamin k epoxide reductase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6351967_0	296591.Bpro_4727	3.626e-166	549.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,4ACDU@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM NnrS family protein	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
PYH2_k127_6351967_6	420662.Mpe_A1076	1.812e-14	74.0	COG4772@1|root,COG4772@2|Bacteria,1MUIH@1224|Proteobacteria,2VKC9@28216|Betaproteobacteria,1KJ2Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	TonB dependent receptor	yncD	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH2_k127_6352342_6	987059.RBXJA2T_12677	7.527e-66	226.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,1KKSA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
PYH2_k127_6352342_3	395495.Lcho_1502	7.115e-101	331.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,1KK8V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
PYH2_k127_6352342_4	987059.RBXJA2T_12687	1.101e-97	322.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,1KJ3B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
PYH2_k127_6352342_1	864051.BurJ1DRAFT_3606	2.375e-260	815.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,1KJQN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
PYH2_k127_6352342_5	420662.Mpe_A1407	2.236e-74	252.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,1KKQE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADH dehydrogenase	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
PYH2_k127_6352342_0	1265502.KB905936_gene2659	2.75e-269	833.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,4AAFV@80864|Comamonadaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
PYH2_k127_6352342_2	1265502.KB905936_gene2658	1.245e-238	742.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,4AC2I@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM NADH-quinone oxidoreductase, chain G	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
PYH2_k127_637399_2	395495.Lcho_0055	2.06e-78	269.0	COG3850@1|root,COG3850@2|Bacteria,1QW6N@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	2.7.13.3,4.6.1.1	ko:K01768,ko:K07678	ko00230,ko02020,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02025,map02026,map04113,map04213,map05111	M00475,M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF2222,GAF_2,Guanylate_cyc,HAMP,dCache_1
PYH2_k127_637399_7	189753.AXAS01000008_gene6759	8.634e-09	58.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JUJ0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_637399_6	1121439.dsat_2621	9.766e-12	72.0	COG4118@1|root,COG4118@2|Bacteria,1Q43S@1224|Proteobacteria,42VPT@68525|delta/epsilon subdivisions,2WS3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
PYH2_k127_637399_5	251221.35211194	1.36e-17	84.0	COG4113@1|root,COG4113@2|Bacteria,1G71V@1117|Cyanobacteria	1117|Cyanobacteria	S	to nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
PYH2_k127_637399_8	886293.Sinac_4101	5.32e-05	49.0	COG4113@1|root,COG4113@2|Bacteria,2J4AP@203682|Planctomycetes	203682|Planctomycetes	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_637399_1	189753.AXAS01000030_gene7102	2.51e-81	282.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_637399_3	1126627.BAWE01000002_gene856	3.07e-65	237.0	COG2984@1|root,COG2984@2|Bacteria,1R7C2@1224|Proteobacteria,2TZKG@28211|Alphaproteobacteria,3JXR0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
PYH2_k127_637399_0	338969.Rfer_2479	1.585e-278	865.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VMJK@28216|Betaproteobacteria,4AG8M@80864|Comamonadaceae	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
PYH2_k127_637399_4	189753.AXAS01000023_gene881	1.473e-28	119.0	COG2984@1|root,COG2984@2|Bacteria,1P0YU@1224|Proteobacteria,2UVTN@28211|Alphaproteobacteria,3K4UC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind
PYH2_k127_6422979_8	296591.Bpro_1509	7.935e-39	146.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VHC1@28216|Betaproteobacteria,4AJ6S@80864|Comamonadaceae	28216|Betaproteobacteria	C	Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0)	-	-	1.16.1.1	ko:K00520,ko:K21739	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
PYH2_k127_6422979_10	983917.RGE_11050	1.494e-29	132.0	COG3152@1|root,COG3152@2|Bacteria,1QECM@1224|Proteobacteria,2VXXF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
PYH2_k127_6422979_4	420662.Mpe_A1073	1.006e-157	508.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,1KJH6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PYH2_k127_6422979_5	1265502.KB905942_gene2805	7.728e-122	395.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,4ACBH@80864|Comamonadaceae	28216|Betaproteobacteria	L	Endonuclease exonuclease phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
PYH2_k127_6422979_7	420662.Mpe_A1071	8.361e-74	252.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,1KKSR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nudix hydrolase	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
PYH2_k127_6422979_3	395019.Bmul_3232	6.623e-180	590.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,2VH4W@28216|Betaproteobacteria,1JZW3@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
PYH2_k127_6422979_0	420662.Mpe_A1070	0.0	1046.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,1KITM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
PYH2_k127_6422979_6	420662.Mpe_A1069	2.23e-107	351.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,1KIU7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
PYH2_k127_6422979_9	864051.BurJ1DRAFT_1303	3.686e-35	136.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,1KMDJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
PYH2_k127_6422979_2	864051.BurJ1DRAFT_1302	9.564e-209	660.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,1KMQC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
PYH2_k127_6422979_1	864051.BurJ1DRAFT_1300	1.301e-247	772.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,1KIWJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
PYH2_k127_643891_1	1157708.KB907451_gene4945	4.958e-175	566.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VI73@28216|Betaproteobacteria,4ABXD@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM monooxygenase FAD-binding	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
PYH2_k127_643891_5	864051.BurJ1DRAFT_0764	3.324e-18	87.0	2E3JP@1|root,32YI0@2|Bacteria,1N6ZI@1224|Proteobacteria,2VWGY@28216|Betaproteobacteria,1KMSM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2783
PYH2_k127_643891_0	1192124.LIG30_4307	1.698e-275	856.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2VI73@28216|Betaproteobacteria,1K3XK@119060|Burkholderiaceae	28216|Betaproteobacteria	CH	PFAM monooxygenase FAD-binding	-	-	1.14.13.127	ko:K05712	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06786,R06787	RC00236	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
PYH2_k127_643891_3	1123504.JQKD01000008_gene5307	6.114e-97	320.0	COG0346@1|root,COG0346@2|Bacteria,1MWCV@1224|Proteobacteria,2VNZN@28216|Betaproteobacteria,4ABGD@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
PYH2_k127_643891_2	1265502.KB905934_gene3254	1.014e-172	545.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,2VI82@28216|Betaproteobacteria,4ABA1@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH2_k127_643891_4	322710.Avin_00670	1.396e-22	98.0	2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,1SFHW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
PYH2_k127_6483801_0	296591.Bpro_0275	3.953e-134	432.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VKC1@28216|Betaproteobacteria,4ABYH@80864|Comamonadaceae	28216|Betaproteobacteria	C	e3 binding domain	bkdB	-	2.3.1.168	ko:K09699	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R02662,R03174,R04097,R10998	RC00004,RC02727,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH2_k127_6483801_2	292415.Tbd_2162	2.87e-71	246.0	COG2230@1|root,COG2230@2|Bacteria	2|Bacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.265	ko:K16868	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_25
PYH2_k127_6483801_1	76114.ebA822	1.336e-116	379.0	COG1656@1|root,COG1656@2|Bacteria,1R442@1224|Proteobacteria,2VN8Q@28216|Betaproteobacteria,2KYAP@206389|Rhodocyclales	206389|Rhodocyclales	S	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
PYH2_k127_6483801_3	420662.Mpe_A1032	3.258e-25	108.0	2CEXV@1|root,32S0S@2|Bacteria,1MZKB@1224|Proteobacteria,2VU8J@28216|Betaproteobacteria,1KMC0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Type II secretion system protein B	gspB	-	-	ko:K02451	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	T2SSB
PYH2_k127_6484755_2	395495.Lcho_0047	2.123e-222	699.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1N58A@1224|Proteobacteria,2VHVP@28216|Betaproteobacteria,1KN51@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	yfhK	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
PYH2_k127_6484755_4	395495.Lcho_0046	1.865e-49	183.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,2VVWD@28216|Betaproteobacteria,1KPCJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
PYH2_k127_6484755_3	395495.Lcho_0045	1.523e-158	518.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
PYH2_k127_6484755_1	318996.AXAZ01000015_gene3633	7.563e-228	728.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,3JR8W@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,TPR_8,TolB_N
PYH2_k127_6484755_0	1041159.AZUW01000008_gene4443	1.426e-230	758.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1
PYH2_k127_6518706_1	1265502.KB905954_gene428	2.67e-130	430.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,4ADJN@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PYH2_k127_6518706_8	420662.Mpe_A1150	1.49e-15	88.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,1KJAN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PYH2_k127_6518706_3	420662.Mpe_A1151	6.628e-92	316.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,1KJ2T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	epsR	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH2_k127_6518706_7	1265502.KB905954_gene425	1.897e-63	228.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,2VQFV@28216|Betaproteobacteria,4ADKH@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM MaoC domain protein dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
PYH2_k127_6518706_4	864051.BurJ1DRAFT_4871	3.599e-85	287.0	COG2249@1|root,COG2249@2|Bacteria,1MXFT@1224|Proteobacteria,2VMX3@28216|Betaproteobacteria,1KPAW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Flavodoxin-like fold	kefF	-	1.6.5.2	ko:K00355,ko:K11746,ko:K11748	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000,ko02000	2.A.37.1.1,2.A.37.1.2	-	-	Flavodoxin_2
PYH2_k127_6518706_0	864051.BurJ1DRAFT_4872	9.111e-256	802.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,1KJ0K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefC	-	-	ko:K03455,ko:K11745,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.1,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_N
PYH2_k127_6518706_2	420662.Mpe_A1099	1.921e-103	347.0	COG0730@1|root,COG0730@2|Bacteria,1MVY3@1224|Proteobacteria,2VIZS@28216|Betaproteobacteria,1KKHP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH2_k127_6518706_5	1265502.KB905954_gene421	1.968e-64	224.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,4ADZM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
PYH2_k127_6518706_6	471854.Dfer_3275	2.976e-64	244.0	COG2114@1|root,COG2114@2|Bacteria,4NKWT@976|Bacteroidetes,47XVT@768503|Cytophagia	976|Bacteroidetes	T	Protein of unknown function (DUF2652)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2652
PYH2_k127_6527998_12	543728.Vapar_3492	5.221e-46	173.0	COG1846@1|root,COG1846@2|Bacteria,1N7BV@1224|Proteobacteria,2VU53@28216|Betaproteobacteria,4AE94@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	marR	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
PYH2_k127_6527998_8	338969.Rfer_4072	9.427e-71	243.0	COG4635@1|root,COG4635@2|Bacteria,1RAH2@1224|Proteobacteria,2VSTC@28216|Betaproteobacteria,4AHVS@80864|Comamonadaceae	28216|Betaproteobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
PYH2_k127_6527998_13	998674.ATTE01000001_gene3700	6.228e-20	100.0	COG3245@1|root,COG3245@2|Bacteria,1MZBZ@1224|Proteobacteria,1S9Z9@1236|Gammaproteobacteria,4618P@72273|Thiotrichales	72273|Thiotrichales	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH2_k127_6527998_4	420662.Mpe_A1468	8.177e-137	438.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,1KK3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
PYH2_k127_6527998_6	983917.RGE_21460	1.789e-98	328.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,1KJE1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
PYH2_k127_6527998_0	543728.Vapar_2357	0.0	1190.0	COG2885@1|root,COG3808@1|root,COG2885@2|Bacteria,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,4AA75@80864|Comamonadaceae	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
PYH2_k127_6527998_5	864051.BurJ1DRAFT_3016	1.138e-99	327.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,1KJXW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
PYH2_k127_6527998_1	420662.Mpe_A2119	0.0	1169.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,1KJ2V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
PYH2_k127_6527998_3	420662.Mpe_A2114	1.47e-166	537.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,1KIYB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
PYH2_k127_6527998_2	864051.BurJ1DRAFT_3013	6.226e-275	854.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,1KJCK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
PYH2_k127_6527998_9	1265502.KB905935_gene3140	2.334e-58	208.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,4ADYB@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
PYH2_k127_6527998_7	983917.RGE_28130	7.865e-71	244.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,1KKNM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
PYH2_k127_6527998_11	864051.BurJ1DRAFT_3010	1.646e-49	181.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,1KM3N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
PYH2_k127_6527998_10	864051.BurJ1DRAFT_3009	1.883e-57	206.0	COG1714@1|root,COG1714@2|Bacteria,1REEC@1224|Proteobacteria,2VRE0@28216|Betaproteobacteria,1KM4U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
PYH2_k127_6527998_14	395495.Lcho_2896	0.0001071	44.0	2E3UK@1|root,32YRY@2|Bacteria,1N74J@1224|Proteobacteria,2VVQ2@28216|Betaproteobacteria,1KM76@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
PYH2_k127_6543241_11	1095769.CAHF01000011_gene2191	1.865e-25	107.0	COG1028@1|root,COG1028@2|Bacteria,1MVYJ@1224|Proteobacteria,2VH22@28216|Betaproteobacteria,475T6@75682|Oxalobacteraceae	28216|Betaproteobacteria	IQ	KR domain	gno1	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
PYH2_k127_6543241_1	1286631.X805_35780	2.117e-315	973.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VH3R@28216|Betaproteobacteria,1KJXM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Acetyl-CoA dehydrogenase C-terminal like	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
PYH2_k127_6543241_10	1278309.KB907101_gene588	9.835e-36	140.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,1S5X4@1236|Gammaproteobacteria,1XKVF@135619|Oceanospirillales	135619|Oceanospirillales	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH2_k127_6543241_6	1280947.HY30_03170	4.308e-116	381.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,2TSK5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	dhmA	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
PYH2_k127_6543241_3	1265502.KB905940_gene2998	1.999e-216	676.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,4AA4T@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_6543241_2	614083.AWQR01000018_gene1736	5.174e-228	715.0	COG0624@1|root,COG0624@2|Bacteria,1MWJS@1224|Proteobacteria,2VHMV@28216|Betaproteobacteria,4AAI9@80864|Comamonadaceae	28216|Betaproteobacteria	E	peptidase dimerisation domain protein	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
PYH2_k127_6543241_0	1265502.KB905940_gene2999	0.0	1154.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VH0Y@28216|Betaproteobacteria,4AAYN@80864|Comamonadaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase NAD-binding	fadB	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH2_k127_6543241_7	1205680.CAKO01000007_gene4392	1.249e-113	371.0	COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria,2JQ14@204441|Rhodospirillales	204441|Rhodospirillales	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_6543241_8	859657.RPSI07_1794	1.637e-110	376.0	COG0411@1|root,COG0411@2|Bacteria,1MX51@1224|Proteobacteria,2VIKW@28216|Betaproteobacteria,1JZVH@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_6543241_5	426117.M446_3167	6.52e-149	484.0	COG4177@1|root,COG4177@2|Bacteria,1MY3V@1224|Proteobacteria,2U0TU@28211|Alphaproteobacteria,1JXQ1@119045|Methylobacteriaceae	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_6543241_9	75379.Tint_0905	2.174e-75	263.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VJAM@28216|Betaproteobacteria,1KJNC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_6543241_4	258594.RPA4034	1.506e-149	479.0	COG0683@1|root,COG0683@2|Bacteria,1MWH7@1224|Proteobacteria,2TS8K@28211|Alphaproteobacteria,3JUFA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Periplasmic binding protein domain	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_6543507_0	1353531.AZNX01000032_gene5905	1.657e-94	334.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,4BM4C@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA,dCache_1
PYH2_k127_6545646_11	886293.Sinac_2077	1.731e-07	55.0	COG1020@1|root,COG1020@2|Bacteria	2|Bacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KR,PP-binding,Thioesterase
PYH2_k127_6545646_7	1051632.TPY_0530	5.737e-82	289.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
PYH2_k127_6545646_10	864051.BurJ1DRAFT_4617	4.535e-14	74.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2VNJ6@28216|Betaproteobacteria,1KN3N@119065|unclassified Burkholderiales	1224|Proteobacteria	E	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
PYH2_k127_6545646_8	76114.ebA6033	2.803e-51	183.0	COG4226@1|root,COG4226@2|Bacteria,1MZYR@1224|Proteobacteria,2VUYG@28216|Betaproteobacteria,2KZMH@206389|Rhodocyclales	206389|Rhodocyclales	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
PYH2_k127_6545646_9	1245471.PCA10_06910	3.563e-30	121.0	2BHA9@1|root,32BBU@2|Bacteria,1PXUQ@1224|Proteobacteria,1TCH6@1236|Gammaproteobacteria,1YKBT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
PYH2_k127_6545646_6	1380394.JADL01000002_gene1161	4.25e-102	339.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2TSE7@28211|Alphaproteobacteria,2JUYN@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_6545646_4	1380394.JADL01000002_gene1160	7.834e-106	348.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2U1BU@28211|Alphaproteobacteria,2JW92@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PYH2_k127_6545646_3	1380394.JADL01000002_gene1159	8.567e-134	435.0	COG0559@1|root,COG0559@2|Bacteria,1MXGK@1224|Proteobacteria,2TVKT@28211|Alphaproteobacteria,2JVW1@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH2_k127_6545646_1	1380394.JADL01000002_gene1158	4.406e-141	473.0	COG4177@1|root,COG4177@2|Bacteria,1P0DF@1224|Proteobacteria,2TUBF@28211|Alphaproteobacteria,2JUXE@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH2_k127_6545646_0	1380394.JADL01000002_gene1156	9.596e-191	602.0	COG0683@1|root,COG0683@2|Bacteria,1MV1Z@1224|Proteobacteria,2TRTD@28211|Alphaproteobacteria,2JT93@204441|Rhodospirillales	204441|Rhodospirillales	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH2_k127_6545646_2	420662.Mpe_A3317	3.616e-135	436.0	COG0583@1|root,COG0583@2|Bacteria,1MUNN@1224|Proteobacteria,2VKER@28216|Betaproteobacteria,1KKXA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_6545646_5	1198452.Jab_2c03540	8.718e-104	343.0	COG1018@1|root,COG3576@1|root,COG1018@2|Bacteria,COG3576@2|Bacteria,1NBWC@1224|Proteobacteria,2VKQ8@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pyridoxamine 5'-phosphate	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
PYH2_k127_6596506_2	864051.BurJ1DRAFT_1546	6.353e-180	570.0	COG1638@1|root,COG1638@2|Bacteria,1MVHI@1224|Proteobacteria,2VHPP@28216|Betaproteobacteria,1KNBY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	PFAM Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH2_k127_6596506_4	395495.Lcho_1332	1.17e-53	194.0	COG3090@1|root,COG3090@2|Bacteria,1N9D4@1224|Proteobacteria,2VT71@28216|Betaproteobacteria,1KMMI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PYH2_k127_6596506_1	1265502.KB905934_gene3261	3.339e-211	669.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VIE2@28216|Betaproteobacteria,4ACB3@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	-	-	-	-	-	-	-	-	-	DctM
PYH2_k127_6596506_3	345341.KUTG_00976	1.74e-134	461.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DYN9@85010|Pseudonocardiales	201174|Actinobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
PYH2_k127_6596506_5	566466.NOR53_1720	2.524e-06	60.0	2AGHX@1|root,316QI@2|Bacteria,1RI7I@1224|Proteobacteria,1S8W9@1236|Gammaproteobacteria,1J9ZI@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6596506_0	864051.BurJ1DRAFT_4157	4.886e-230	719.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,1KJVF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
PYH2_k127_6616431_1	595537.Varpa_5383	3.018e-94	317.0	COG2186@1|root,COG2186@2|Bacteria,1MUP9@1224|Proteobacteria,2VZB1@28216|Betaproteobacteria,4ACMQ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
PYH2_k127_6616431_0	296591.Bpro_1257	4.959e-182	575.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,4ADBU@80864|Comamonadaceae	28216|Betaproteobacteria	P	TOBE domain	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
PYH2_k127_6616431_2	864051.BurJ1DRAFT_0687	4.716e-91	304.0	COG1653@1|root,COG1653@2|Bacteria,1MU64@1224|Proteobacteria,2VJYY@28216|Betaproteobacteria	28216|Betaproteobacteria	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
PYH2_k127_6617005_0	420662.Mpe_A2005	4.924e-132	428.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,1KJVW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KL	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
PYH2_k127_6617005_2	864051.BurJ1DRAFT_2964	1.865e-113	371.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KK72@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
PYH2_k127_6617005_1	987059.RBXJA2T_08048	6.585e-132	430.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,1KJ8M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PYH2_k127_6617005_3	420662.Mpe_A2002	5.537e-87	294.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,1KK1G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
PYH2_k127_6624250_13	411463.EUBVEN_01982	1.354e-09	68.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,25W2D@186806|Eubacteriaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PYH2_k127_6624250_2	76114.ebA3141	3.236e-281	881.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VZ4I@28216|Betaproteobacteria,2KYDZ@206389|Rhodocyclales	206389|Rhodocyclales	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ppcB	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
PYH2_k127_6624250_6	748247.AZKH_p0131	1.23e-83	298.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,2VY80@28216|Betaproteobacteria,2KXI3@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain in cystathionine beta-synthase and other proteins.	ppsC	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
PYH2_k127_6624250_4	76114.ebA3143	5.562e-177	562.0	COG0574@1|root,COG0574@2|Bacteria,1MU0R@1224|Proteobacteria,2W1M2@28216|Betaproteobacteria,2KXQ3@206389|Rhodocyclales	206389|Rhodocyclales	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
PYH2_k127_6624250_0	76114.ebA3144	0.0	1084.0	COG3848@1|root,COG3848@2|Bacteria,1MV5C@1224|Proteobacteria,2VZBP@28216|Betaproteobacteria,2KYFA@206389|Rhodocyclales	206389|Rhodocyclales	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
PYH2_k127_6624250_1	76114.ebA3145	1.316e-282	878.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,2VIKD@28216|Betaproteobacteria,2KUEW@206389|Rhodocyclales	206389|Rhodocyclales	K	Fis family transcriptional regulator	poxR	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
PYH2_k127_6624250_7	76114.ebA3146	2.051e-55	203.0	COG3787@1|root,COG3787@2|Bacteria,1PV3C@1224|Proteobacteria,2WB2H@28216|Betaproteobacteria,2KYQQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K09979	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
PYH2_k127_6624250_8	395495.Lcho_2391	3.283e-55	199.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_6624250_3	420662.Mpe_A1307	3.901e-214	677.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria,1KK66@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
PYH2_k127_6624250_14	748280.NH8B_4056	1.155e-07	56.0	2E08V@1|root,32VWG@2|Bacteria,1N52T@1224|Proteobacteria,2VU56@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6624250_12	296591.Bpro_1275	4.146e-24	106.0	COG4274@1|root,COG4274@2|Bacteria,1RKGA@1224|Proteobacteria	1224|Proteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
PYH2_k127_6624250_5	420662.Mpe_A3342	4.673e-84	284.0	COG4372@1|root,COG4372@2|Bacteria,1RKIE@1224|Proteobacteria,2VSID@28216|Betaproteobacteria,1KNHZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6624250_10	1538295.JY96_06415	6.968e-31	123.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1KMII@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Cold shock protein	cspC	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
PYH2_k127_6624250_9	983917.RGE_38020	1.288e-36	139.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria,1KMDV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA1	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
PYH2_k127_6624250_11	196367.JNFG01000022_gene5083	1.643e-28	118.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,1K37E@119060|Burkholderiaceae	28216|Betaproteobacteria	C	oxidoreductase	porG	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
PYH2_k127_663369_12	886293.Sinac_3852	5.964e-33	129.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061,ko:K07100	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
PYH2_k127_663369_2	864051.BurJ1DRAFT_1545	1.051e-201	631.0	COG0620@1|root,COG0620@2|Bacteria,1MV2Z@1224|Proteobacteria,2VKXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Methionine synthase	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
PYH2_k127_663369_7	296591.Bpro_2056	3.366e-74	256.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	cpeZ	-	-	ko:K05384,ko:K05386	ko00196,ko01100,map00196,map01100	-	-	-	ko00000,ko00001,ko00194	-	-	-	HEAT_2
PYH2_k127_663369_13	1123367.C666_15525	8.909e-29	126.0	2BSVP@1|root,32MZ8@2|Bacteria,1N04T@1224|Proteobacteria,2VX8Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
PYH2_k127_663369_6	1415630.U771_26865	2.787e-87	308.0	COG2199@1|root,COG2199@2|Bacteria,1MXY1@1224|Proteobacteria,1RXYD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	yfiN	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0032153,GO:0032879,GO:0033554,GO:0036460,GO:0040012,GO:0040013,GO:0042802,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051270,GO:0051271,GO:0051716,GO:0052621,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146	2.7.7.65	ko:K20956,ko:K21021	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001,ko01000	-	-	-	CHASE,CHASE8,GGDEF,PAS_4
PYH2_k127_663369_11	266264.Rmet_2246	7.731e-38	147.0	COG2885@1|root,COG2885@2|Bacteria,1RJ05@1224|Proteobacteria,2VTXD@28216|Betaproteobacteria,1K9U6@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
PYH2_k127_663369_15	1100720.ALKN01000045_gene434	6.713e-07	56.0	COG0697@1|root,COG0697@2|Bacteria,1MXVF@1224|Proteobacteria,2VKMQ@28216|Betaproteobacteria,4ACBS@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Permeases of the drug metabolite transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_663369_5	1005048.CFU_1981	2.557e-120	400.0	COG0457@1|root,COG0457@2|Bacteria,1MUTV@1224|Proteobacteria,2VSDY@28216|Betaproteobacteria,475DB@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
PYH2_k127_663369_4	1157708.KB907453_gene4113	6.827e-153	495.0	COG1878@1|root,COG1878@2|Bacteria,1MWWB@1224|Proteobacteria,2VJXW@28216|Betaproteobacteria,4ADDF@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM cyclase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
PYH2_k127_663369_1	543728.Vapar_1497	8.575e-232	723.0	COG1028@1|root,COG1545@1|root,COG1028@2|Bacteria,COG1545@2|Bacteria,1QVCC@1224|Proteobacteria,2WHP0@28216|Betaproteobacteria,4ABTV@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc,adh_short
PYH2_k127_663369_3	543728.Vapar_1496	1.256e-199	649.0	COG0183@1|root,COG0183@2|Bacteria,1MUZV@1224|Proteobacteria,2VM79@28216|Betaproteobacteria,4ADCU@80864|Comamonadaceae	28216|Betaproteobacteria	I	acetyl-coa acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_663369_0	1157708.KB907453_gene4110	2.633e-250	783.0	COG0318@1|root,COG0318@2|Bacteria,1MWSD@1224|Proteobacteria,2VJYZ@28216|Betaproteobacteria,4AC18@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_663369_16	243233.MCA3006	3.588e-05	48.0	COG2002@1|root,COG2002@2|Bacteria,1NAGM@1224|Proteobacteria,1SE22@1236|Gammaproteobacteria,1XGPD@135618|Methylococcales	135618|Methylococcales	K	prlF antitoxin for toxin YhaV_toxin	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_663369_8	748247.AZKH_p0451	5.922e-67	234.0	COG0625@1|root,COG0625@2|Bacteria,1PPF9@1224|Proteobacteria,2VQQZ@28216|Betaproteobacteria,2KYGR@206389|Rhodocyclales	206389|Rhodocyclales	O	Glutathione S-transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GST_C_3,GST_N
PYH2_k127_663369_14	379066.GAU_1183	5.839e-17	95.0	COG0664@1|root,COG0664@2|Bacteria,1ZTHA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_663369_9	1192034.CAP_2543	3.947e-65	244.0	COG0574@1|root,COG0574@2|Bacteria,1Q9MN@1224|Proteobacteria,434GW@68525|delta/epsilon subdivisions,2WYU9@28221|Deltaproteobacteria,2Z0MI@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
PYH2_k127_663369_10	68223.JNZY01000062_gene1108	2.142e-43	163.0	COG3848@1|root,COG3848@2|Bacteria,2IE61@201174|Actinobacteria	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
PYH2_k127_663990_3	420662.Mpe_A1420	1.776e-10	68.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,1KJIS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
PYH2_k127_663990_2	1458275.AZ34_08190	1.123e-30	138.0	COG3308@1|root,COG3308@2|Bacteria,1N1EF@1224|Proteobacteria,2VU3C@28216|Betaproteobacteria,4AECU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2069)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2069
PYH2_k127_663990_0	420662.Mpe_A1422	6.738e-169	540.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,1KJDV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	UPF0761 membrane protein	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
PYH2_k127_663990_1	864051.BurJ1DRAFT_0723	3.625e-128	433.0	COG1960@1|root,COG1960@2|Bacteria,1MVAH@1224|Proteobacteria,2VKD1@28216|Betaproteobacteria,1KMYQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	acd12	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_6640066_0	765420.OSCT_0266	5.641e-127	419.0	COG0475@1|root,COG0475@2|Bacteria,2G6B0@200795|Chloroflexi,375SB@32061|Chloroflexia	32061|Chloroflexia	P	PFAM sodium hydrogen exchanger	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
PYH2_k127_6640066_1	864051.BurJ1DRAFT_2219	2.259e-117	387.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VMN7@28216|Betaproteobacteria,1KKDP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.215,1.1.1.79,1.1.1.81	ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH2_k127_6640629_12	864051.BurJ1DRAFT_4942	2.653e-102	340.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,1KK52@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
PYH2_k127_6640629_11	1538295.JY96_14480	4.778e-106	347.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,1KJ7M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
PYH2_k127_6640629_9	864051.BurJ1DRAFT_4944	2.882e-124	422.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,1KKAB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	phosphatase	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
PYH2_k127_6640629_13	420662.Mpe_A0069	1.755e-84	293.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,1KJ47@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	PFAM Protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
PYH2_k127_6640629_7	420662.Mpe_A0071	3.619e-172	544.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,1KJK8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013	6.2.1.5,6.2.1.9	ko:K01902,ko:K08692	ko00020,ko00630,ko00640,ko00660,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00630,map00640,map00660,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00346,M00374,M00620	R00405,R01256,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
PYH2_k127_6640629_3	983917.RGE_12340	1.862e-199	631.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,1KIU3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
PYH2_k127_6640629_18	420662.Mpe_A0074	4.931e-35	141.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,1KMD0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
PYH2_k127_6640629_4	1265502.KB905944_gene708	1.176e-198	623.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,4AANZ@80864|Comamonadaceae	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
PYH2_k127_6640629_8	864051.BurJ1DRAFT_4953	2.268e-124	400.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,1KK1U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PFAM response regulator receiver	basR_3	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH2_k127_6640629_5	420662.Mpe_A0077	3.984e-197	626.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGRW@28216|Betaproteobacteria,1KK18@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	two-component sensor kinase	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
PYH2_k127_6640629_15	1100720.ALKN01000030_gene1176	7.754e-79	272.0	COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,2VKIK@28216|Betaproteobacteria,4AACB@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31,1.1.1.411	ko:K00020,ko:K08319	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
PYH2_k127_6640629_6	864051.BurJ1DRAFT_4956	2.634e-195	617.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,1KJS3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
PYH2_k127_6640629_0	864051.BurJ1DRAFT_4957	0.0	1021.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,1KIXY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
PYH2_k127_6640629_14	420662.Mpe_A0081	3.219e-80	271.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,1KKT1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Rod shape-determining protein mreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
PYH2_k127_6640629_10	864051.BurJ1DRAFT_4959	1.956e-113	373.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,1KJT7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
PYH2_k127_6640629_2	864051.BurJ1DRAFT_4960	1.531e-215	671.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,1KJW1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
PYH2_k127_6640629_17	864051.BurJ1DRAFT_4961	4.015e-37	144.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,1KM98@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
PYH2_k127_6640629_1	864051.BurJ1DRAFT_4962	3.356e-241	761.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,1KJ1C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH2_k127_6640629_16	983917.RGE_46700	1.584e-68	239.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,1KJ6W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
PYH2_k127_667152_2	1411123.JQNH01000001_gene2724	3.923e-42	160.0	COG1638@1|root,COG1638@2|Bacteria,1NTFS@1224|Proteobacteria,2U1QM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	DctP
PYH2_k127_667152_3	1231391.AMZF01000029_gene227	9.071e-35	144.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	ko:K07013,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	V4R
PYH2_k127_667152_0	338969.Rfer_1643	3.544e-154	493.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,4A9RA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_667152_1	1538295.JY96_09425	4.051e-63	237.0	COG0431@1|root,COG0431@2|Bacteria,1QU9C@1224|Proteobacteria,2WGJP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PYH2_k127_6674432_1	420662.Mpe_A1225	1.619e-245	770.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,2VZ4H@28216|Betaproteobacteria,1KN47@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
PYH2_k127_6674432_0	420662.Mpe_A1224	7.366e-261	817.0	COG0457@1|root,COG0457@2|Bacteria,1MXSS@1224|Proteobacteria,2VZB4@28216|Betaproteobacteria,1KN0Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6674432_2	420662.Mpe_A1223	7.659e-89	294.0	2B4XH@1|root,31XQC@2|Bacteria,1RHJF@1224|Proteobacteria,2W1BJ@28216|Betaproteobacteria,1KNAC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6680491_7	511062.GU3_00290	7.768e-16	86.0	COG3915@1|root,COG3915@2|Bacteria,1RHJS@1224|Proteobacteria,1S0M5@1236|Gammaproteobacteria,1Y6E2@135624|Aeromonadales	135624|Aeromonadales	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6680491_6	686578.AFFX01000001_gene1507	1.246e-74	272.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1T23Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1,dCache_3
PYH2_k127_6680491_3	365046.Rta_16580	9.097e-95	314.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,4AA3R@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
PYH2_k127_6680491_5	864051.BurJ1DRAFT_3644	6.174e-80	285.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,2VJ7T@28216|Betaproteobacteria,1KMIG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	btuF	-	-	ko:K02016,ko:K06858	ko02010,map02010	M00240,M00241	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.13,3.A.1.14	-	-	Peripla_BP_2
PYH2_k127_6680491_0	420662.Mpe_A0899	1.652e-113	388.0	COG0604@1|root,COG0604@2|Bacteria,1MXRX@1224|Proteobacteria,2VKQT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_6680491_1	420662.Mpe_A1818	1.519e-109	359.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,2VKM0@28216|Betaproteobacteria,1KJAF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
PYH2_k127_6680491_4	395495.Lcho_1904	3.753e-94	315.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2VNKF@28216|Betaproteobacteria,1KKPR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
PYH2_k127_6680491_2	1265502.KB905940_gene2951	1.259e-108	356.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,4AAVB@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
PYH2_k127_6696505_4	395495.Lcho_1955	3.931e-09	61.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,2VSQW@28216|Betaproteobacteria,1KNPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
PYH2_k127_6696505_1	395495.Lcho_2216	1.314e-175	565.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VKKF@28216|Betaproteobacteria,1KJTI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
PYH2_k127_6696505_0	420662.Mpe_A1336	1.237e-259	812.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,2VIJY@28216|Betaproteobacteria,1KJ6Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF853)	yjgR	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853
PYH2_k127_6696505_2	1265502.KB905929_gene2230	2.166e-130	418.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,4AANU@80864|Comamonadaceae	28216|Betaproteobacteria	K	transcriptional regulatory protein	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
PYH2_k127_6696505_3	1265502.KB905929_gene2231	6.056e-73	249.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,4A9X8@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
PYH2_k127_6710803_5	1265502.KB905979_gene498	1.394e-09	62.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VI0I@28216|Betaproteobacteria,4AB4Z@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
PYH2_k127_6710803_3	987059.RBXJA2T_01655	2.514e-75	260.0	2AYXV@1|root,31R3M@2|Bacteria,1RHPG@1224|Proteobacteria,2VS4A@28216|Betaproteobacteria,1KKT6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6710803_4	420662.Mpe_A0351	5.062e-45	169.0	2DQ04@1|root,33466@2|Bacteria,1NA4M@1224|Proteobacteria,2VTGQ@28216|Betaproteobacteria,1KMNS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TAT_signal
PYH2_k127_6710803_0	420662.Mpe_A0350	2.344e-247	777.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,2VHUP@28216|Betaproteobacteria,1KIYI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	GMC family oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
PYH2_k127_6710803_2	1265502.KB905979_gene501	4.517e-104	349.0	COG1075@1|root,COG1075@2|Bacteria,1R75P@1224|Proteobacteria,2VU4P@28216|Betaproteobacteria,4ADQ9@80864|Comamonadaceae	28216|Betaproteobacteria	S	PGAP1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,PGAP1
PYH2_k127_6710803_1	420662.Mpe_A0346	2.828e-212	662.0	COG3185@1|root,COG3185@2|Bacteria,1MUVZ@1224|Proteobacteria,2VJCK@28216|Betaproteobacteria,1KJ27@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	PFAM Glyoxalase bleomycin resistance protein dioxygenase	hppD	-	1.13.11.27	ko:K00457	ko00130,ko00350,ko00360,ko01100,map00130,map00350,map00360,map01100	M00044	R01372,R02521	RC00505,RC00738	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
PYH2_k127_6743659_3	522306.CAP2UW1_2978	8.62e-136	437.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PYH2_k127_6743659_4	614083.AWQR01000047_gene3258	2.441e-95	320.0	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,2VN94@28216|Betaproteobacteria,4AF6F@80864|Comamonadaceae	28216|Betaproteobacteria	G	Strictosidine synthase	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2,SGL,Str_synth
PYH2_k127_6743659_7	358220.C380_18915	2.417e-62	220.0	COG3386@1|root,COG3386@2|Bacteria,1MX7V@1224|Proteobacteria,2VN94@28216|Betaproteobacteria,4AF6F@80864|Comamonadaceae	28216|Betaproteobacteria	G	Strictosidine synthase	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2,SGL,Str_synth
PYH2_k127_6743659_9	666685.R2APBS1_2752	7.775e-46	169.0	2E31J@1|root,32Y1Y@2|Bacteria,1N745@1224|Proteobacteria,1SCMM@1236|Gammaproteobacteria,1X8QA@135614|Xanthomonadales	135614|Xanthomonadales	S	MAPEG family	-	-	-	-	-	-	-	-	-	-	-	-	MAPEG
PYH2_k127_6743659_12	443598.AUFA01000127_gene7209	1.25e-09	64.0	COG2984@1|root,COG2984@2|Bacteria,1RDUT@1224|Proteobacteria,2U8XC@28211|Alphaproteobacteria,3JYZA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_6743659_5	338969.Rfer_3456	2.712e-95	321.0	COG3228@1|root,COG3228@2|Bacteria,1RAHF@1224|Proteobacteria,2VJTJ@28216|Betaproteobacteria,4ACNB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the MtfA family	mtfA	-	-	ko:K09933	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M90
PYH2_k127_6743659_1	1454004.AW11_03331	3.455e-188	603.0	COG1226@1|root,COG1226@2|Bacteria,1R4J8@1224|Proteobacteria	1224|Proteobacteria	P	Ion transport 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2,TrkA_C,TrkA_N
PYH2_k127_6743659_6	1100720.ALKN01000030_gene1161	4.182e-64	222.0	COG1917@1|root,COG1917@2|Bacteria,1NNBT@1224|Proteobacteria,2VWRN@28216|Betaproteobacteria,4AJDV@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_6743659_2	1038866.KB902793_gene6132	7.062e-184	589.0	COG0471@1|root,COG0471@2|Bacteria,1MUSA@1224|Proteobacteria,2TU0C@28211|Alphaproteobacteria,3JRI4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Sodium:sulfate symporter transmembrane region	-	-	-	ko:K03319,ko:K09477,ko:K11106,ko:K14445	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.47,2.A.47.1,2.A.47.3.2,2.A.47.3.3	-	-	Na_sulph_symp
PYH2_k127_6743659_0	1379270.AUXF01000003_gene3635	1.771e-189	610.0	COG0154@1|root,COG0154@2|Bacteria,1ZUIB@142182|Gemmatimonadetes	142182|Gemmatimonadetes	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
PYH2_k127_6743659_8	313606.M23134_02908	6.681e-50	195.0	COG0123@1|root,COG0123@2|Bacteria,4P0MF@976|Bacteroidetes,47TW8@768503|Cytophagia	976|Bacteroidetes	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
PYH2_k127_6743659_10	314285.KT71_08545	2.35e-32	132.0	COG1418@1|root,COG1418@2|Bacteria,1N6F4@1224|Proteobacteria,1SF9A@1236|Gammaproteobacteria,1J99R@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
PYH2_k127_6743659_11	522306.CAP2UW1_2155	2.726e-30	125.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria	1224|Proteobacteria	S	von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
PYH2_k127_6760725_5	1121440.AUMA01000006_gene1422	8.787e-26	109.0	COG0739@1|root,COG0739@2|Bacteria,1NESH@1224|Proteobacteria,42MGB@68525|delta/epsilon subdivisions,2WJ7F@28221|Deltaproteobacteria,2M7ZK@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
PYH2_k127_6760725_4	1117647.M5M_17045	7.348e-36	144.0	COG0625@1|root,COG0625@2|Bacteria,1QEZP@1224|Proteobacteria,1S3EZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-transferase, C-terminal domain	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3,GST_N
PYH2_k127_6760725_1	365046.Rta_23940	6.263e-129	419.0	COG3181@1|root,COG3181@2|Bacteria,1P25R@1224|Proteobacteria,2VMA6@28216|Betaproteobacteria,4ABJH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_6760725_3	316057.RPD_1533	2.496e-36	145.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2UG0Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
PYH2_k127_6760725_2	85643.Tmz1t_2948	2.22e-111	368.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,2VSQQ@28216|Betaproteobacteria,2KXX8@206389|Rhodocyclales	206389|Rhodocyclales	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	1.3.7.8	ko:K04115	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
PYH2_k127_6760725_0	1187851.A33M_3198	9.728e-190	602.0	COG1924@1|root,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2U1DN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Benzoyl-CoA reductase subunit	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
PYH2_k127_6765256_7	1041159.AZUW01000008_gene4443	4.145e-59	211.0	COG2114@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2TQVN@28211|Alphaproteobacteria,4B81Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,DZR,Guanylate_cyc,SAM_1
PYH2_k127_6765256_10	1286631.X805_36050	3.565e-08	57.0	COG2721@1|root,COG2721@2|Bacteria,1MU9V@1224|Proteobacteria,2VHJB@28216|Betaproteobacteria,1KJ14@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	D-galactarate dehydratase Altronate hydrolase	garD	-	4.2.1.42,4.4.1.24	ko:K01708,ko:K16846	ko00053,ko00270,map00053,map00270	-	R05608,R07633	RC00543,RC01785	ko00000,ko00001,ko01000	-	-	-	GD_AH_C,SAF
PYH2_k127_6765256_0	1265502.KB905948_gene994	8.219e-260	811.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VHCV@28216|Betaproteobacteria,4ABBW@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH2_k127_6765256_4	479434.Sthe_0848	2.785e-117	396.0	COG0001@1|root,COG0001@2|Bacteria,2G67D@200795|Chloroflexi	2|Bacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	atrB	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_6765256_9	1202962.KB907152_gene1115	1.674e-08	64.0	COG3637@1|root,COG3637@2|Bacteria,1RICQ@1224|Proteobacteria,1SF8S@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
PYH2_k127_6765256_2	1238182.C882_3646	5.481e-161	518.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2U4I6@28211|Alphaproteobacteria,2JRIG@204441|Rhodospirillales	204441|Rhodospirillales	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
PYH2_k127_6765256_6	95619.PM1_0214080	2.229e-59	215.0	COG1028@1|root,COG1028@2|Bacteria,1QTU9@1224|Proteobacteria,1T1HD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH2_k127_6765256_3	316055.RPE_3197	3.798e-119	415.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,2U1A9@28211|Alphaproteobacteria,3JXC0@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
PYH2_k127_6765256_5	316055.RPE_3198	3.722e-114	375.0	COG0385@1|root,COG0385@2|Bacteria,1MXF3@1224|Proteobacteria,2U2YW@28211|Alphaproteobacteria,3JYK9@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
PYH2_k127_6765256_1	1002809.SSIL_2408	3.443e-226	718.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli,26DUZ@186818|Planococcaceae	91061|Bacilli	E	COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_6765256_8	76114.ebA2047	2.12e-50	184.0	COG1802@1|root,COG1802@2|Bacteria,1RISU@1224|Proteobacteria,2VVD4@28216|Betaproteobacteria	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_6795902_17	1123355.JHYO01000001_gene3226	3.016e-18	86.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
PYH2_k127_6795902_5	85643.Tmz1t_2956	2.826e-129	421.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,2VIQM@28216|Betaproteobacteria,2KY5Y@206389|Rhodocyclales	206389|Rhodocyclales	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH2_k127_6795902_16	187272.Mlg_0695	5.549e-30	136.0	COG1633@1|root,COG1633@2|Bacteria,1RJFW@1224|Proteobacteria,1S85V@1236|Gammaproteobacteria,1WZFW@135613|Chromatiales	135613|Chromatiales	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PYH2_k127_6795902_14	1244869.H261_12176	2.651e-49	185.0	COG0251@1|root,COG0251@2|Bacteria,1RHSP@1224|Proteobacteria,2U9A9@28211|Alphaproteobacteria,2JSX2@204441|Rhodospirillales	204441|Rhodospirillales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH2_k127_6795902_11	927677.ALVU02000006_gene450	1.625e-86	295.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	ydjP	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH2_k127_6795902_6	365044.Pnap_0299	2.991e-126	415.0	COG0683@1|root,COG0683@2|Bacteria,1MWR8@1224|Proteobacteria,2VHH6@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Extracellular ligand-binding receptor	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH2_k127_6795902_12	522306.CAP2UW1_1398	5.271e-68	241.0	COG3338@1|root,COG3338@2|Bacteria,1PEA6@1224|Proteobacteria,2VI5K@28216|Betaproteobacteria	28216|Betaproteobacteria	P	carbonic anhydrase	cah	-	4.2.1.1	ko:K01674	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Carb_anhydrase,VPEP
PYH2_k127_6795902_8	522306.CAP2UW1_1397	7.354e-117	388.0	COG3386@1|root,COG3386@2|Bacteria	2|Bacteria	G	gluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
PYH2_k127_6795902_15	522306.CAP2UW1_1396	8.022e-31	136.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	wapA	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	AhpC-TSA,NHL,RHS_repeat,Thioredoxin_8
PYH2_k127_6795902_9	1123504.JQKD01000042_gene4657	1.959e-113	370.0	COG0410@1|root,COG0410@2|Bacteria,1MVYI@1224|Proteobacteria,2VHGT@28216|Betaproteobacteria,4ACSD@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_6795902_10	543728.Vapar_0084	1.115e-110	371.0	COG0411@1|root,COG0411@2|Bacteria,1MXHT@1224|Proteobacteria,2VKUM@28216|Betaproteobacteria,4ABGV@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_6795902_4	1157708.KB907451_gene4615	2.001e-137	448.0	COG4177@1|root,COG4177@2|Bacteria,1MUPI@1224|Proteobacteria,2VK9Y@28216|Betaproteobacteria,4AA2K@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_6795902_2	1157708.KB907451_gene4614	2.826e-148	474.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,4AB0U@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_6795902_1	1392838.AWNM01000066_gene1357	2.097e-178	566.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VIK5@28216|Betaproteobacteria,3T31H@506|Alcaligenaceae	28216|Betaproteobacteria	E	ABC-type branched-chain amino acid transport systems periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_6795902_7	296591.Bpro_1623	6.546e-122	401.0	COG2267@1|root,COG2267@2|Bacteria,1NK3M@1224|Proteobacteria,2VKPD@28216|Betaproteobacteria,4ACDS@80864|Comamonadaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH2_k127_6795902_0	1157708.KB907451_gene4611	1.365e-269	844.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VJJS@28216|Betaproteobacteria,4AC26@80864|Comamonadaceae	28216|Betaproteobacteria	I	Benzoate-CoA ligase family	-	-	6.2.1.25	ko:K04110	ko00362,ko00627,ko01100,ko01120,map00362,map00627,map01100,map01120	-	R01422	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_6795902_13	381666.H16_B1916	1.576e-66	229.0	COG1012@1|root,COG1012@2|Bacteria,1QYJ1@1224|Proteobacteria,2WHFK@28216|Betaproteobacteria,1KINX@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Domain of unknown function (DUF4863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4863
PYH2_k127_6795902_3	1157708.KB907451_gene4608	4.339e-140	450.0	COG0703@1|root,COG0703@2|Bacteria,1MX66@1224|Proteobacteria,2VK91@28216|Betaproteobacteria,4ABJG@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK_2	-	-	ko:K15546	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31,SKI
PYH2_k127_6801554_8	395495.Lcho_1692	6.4e-83	276.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,1KJCR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
PYH2_k127_6801554_5	983917.RGE_15900	1.083e-148	492.0	COG0395@1|root,COG0395@2|Bacteria,1MUT9@1224|Proteobacteria,2VIMR@28216|Betaproteobacteria,1KKG7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17317	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
PYH2_k127_6801554_4	1265502.KB905936_gene2634	2.209e-157	500.0	COG1175@1|root,COG1175@2|Bacteria,1MU84@1224|Proteobacteria,2VJFE@28216|Betaproteobacteria,4AAH9@80864|Comamonadaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17316	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	BPD_transp_1
PYH2_k127_6801554_0	983917.RGE_15920	4.46e-220	687.0	COG1653@1|root,COG1653@2|Bacteria,1MUYE@1224|Proteobacteria,2VJ0D@28216|Betaproteobacteria,1KKCQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17315	ko02010,map02010	M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.24,3.A.1.1.30	-	-	SBP_bac_1
PYH2_k127_6801554_6	1268622.AVS7_00615	1.71e-123	403.0	COG4638@1|root,COG4638@2|Bacteria,1MXXI@1224|Proteobacteria,2VNQF@28216|Betaproteobacteria,4AD2M@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
PYH2_k127_6801554_1	420662.Mpe_A0806	1.029e-193	611.0	COG1744@1|root,COG1744@2|Bacteria,1MWTM@1224|Proteobacteria,2VH5W@28216|Betaproteobacteria,1KJ01@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	basic membrane	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
PYH2_k127_6801554_3	420662.Mpe_A0805	4.406e-158	503.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2VHBU@28216|Betaproteobacteria,1KJZ8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PYH2_k127_6801554_2	420662.Mpe_A0804	9.35e-169	537.0	COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,2VH2R@28216|Betaproteobacteria,1KJQH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PYH2_k127_6801554_7	983917.RGE_39990	6.019e-88	293.0	COG3845@1|root,COG3845@2|Bacteria,1NT0H@1224|Proteobacteria,2WGJY@28216|Betaproteobacteria,1KJQ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
PYH2_k127_6801672_0	864051.BurJ1DRAFT_4089	6.4e-323	992.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,1KJ6P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
PYH2_k127_6801672_1	1265502.KB905932_gene1819	5.688e-144	466.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,4AA5K@80864|Comamonadaceae	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PYH2_k127_6801672_2	864051.BurJ1DRAFT_4087	1.332e-98	329.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,1KJ06@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	HAD-hyrolase-like	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PYH2_k127_6801672_3	420662.Mpe_A0659	7.896e-43	161.0	COG2146@1|root,COG2146@2|Bacteria,1N72F@1224|Proteobacteria,2VTX8@28216|Betaproteobacteria,1KMA9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
PYH2_k127_6844015_8	395495.Lcho_0314	1.809e-143	460.0	COG0807@1|root,COG0807@2|Bacteria,1MWUM@1224|Proteobacteria,2VJRX@28216|Betaproteobacteria,1KJRK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Protein of unknown function (DUF1688)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1688
PYH2_k127_6844015_11	983917.RGE_45450	9.162e-112	369.0	COG0035@1|root,COG0035@2|Bacteria,1MV4N@1224|Proteobacteria,2VKM0@28216|Betaproteobacteria,1KJJU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
PYH2_k127_6844015_4	1384054.N790_11960	9.173e-213	685.0	COG0657@1|root,COG2072@1|root,COG0657@2|Bacteria,COG2072@2|Bacteria,1MUQH@1224|Proteobacteria,1RPJY@1236|Gammaproteobacteria,1X6KD@135614|Xanthomonadales	135614|Xanthomonadales	IP	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,FMO-like,Pyr_redox_3
PYH2_k127_6844015_3	983917.RGE_45440	2.868e-226	713.0	COG0402@1|root,COG0402@2|Bacteria,1MX34@1224|Proteobacteria,2VMF2@28216|Betaproteobacteria,1KJH4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Amidohydrolase family	codA	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
PYH2_k127_6844015_13	987059.RBXJA2T_04748	5.938e-107	349.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,1KJKI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glutathione S-transferase	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
PYH2_k127_6844015_5	1265502.KB905962_gene373	1.043e-204	644.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,4AAW1@80864|Comamonadaceae	28216|Betaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
PYH2_k127_6844015_14	1286631.X805_21240	1.1e-104	342.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2VMPA@28216|Betaproteobacteria,1KKGN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
PYH2_k127_6844015_15	1121015.N789_13075	2.425e-97	329.0	COG2267@1|root,COG2267@2|Bacteria,1MWDA@1224|Proteobacteria,1RRJP@1236|Gammaproteobacteria,1X60E@135614|Xanthomonadales	135614|Xanthomonadales	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
PYH2_k127_6844015_10	987059.RBXJA2T_04773	5.027e-113	372.0	COG1024@1|root,COG1024@2|Bacteria,1PJ4R@1224|Proteobacteria,2VKXI@28216|Betaproteobacteria,1KM7G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH2_k127_6844015_2	987059.RBXJA2T_04778	1.067e-250	781.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2VIT5@28216|Betaproteobacteria,1KKBA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_6844015_7	987059.RBXJA2T_02912	1.318e-149	479.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,1KJBW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Phosphotransferase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
PYH2_k127_6844015_1	864051.BurJ1DRAFT_4666	1.046e-271	857.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,1KJYE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
PYH2_k127_6844015_6	983917.RGE_45300	1.149e-155	502.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,1KJ74@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
PYH2_k127_6844015_12	987059.RBXJA2T_02897	5.847e-109	361.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,1KJFN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
PYH2_k127_6844015_16	864051.BurJ1DRAFT_4663	1.634e-71	243.0	COG2732@1|root,COG2732@2|Bacteria,1RD25@1224|Proteobacteria,2VR9C@28216|Betaproteobacteria,1KKU0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
PYH2_k127_6844015_19	983917.RGE_45260	2.564e-43	167.0	COG4290@1|root,COG4290@2|Bacteria,1MZEZ@1224|Proteobacteria,2VTZ7@28216|Betaproteobacteria,1KM9H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Ribonuclease	rnaSA	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
PYH2_k127_6844015_0	1223521.BBJX01000002_gene2881	0.0	1212.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,4AAXI@80864|Comamonadaceae	28216|Betaproteobacteria	C	Phosphate acetyl butaryl transferase	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_DH,Malic_M,PTA_PTB,malic
PYH2_k127_6844015_9	1265502.KB905939_gene2331	5.358e-125	426.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,4AABK@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
PYH2_k127_6844015_17	596154.Alide2_4422	2.768e-62	219.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,4ADZU@80864|Comamonadaceae	28216|Betaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
PYH2_k127_6844015_18	420662.Mpe_A0212	4.234e-46	179.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,1KM1A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
PYH2_k127_687437_2	745411.B3C1_14440	1.653e-15	77.0	COG1028@1|root,COG1028@2|Bacteria,1PFUB@1224|Proteobacteria,1RS3G@1236|Gammaproteobacteria,1J55Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PYH2_k127_687437_1	523791.Kkor_1536	1.339e-141	466.0	COG5316@1|root,COG5316@2|Bacteria,1QCVP@1224|Proteobacteria,1RQFF@1236|Gammaproteobacteria,1XICC@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
PYH2_k127_687437_0	1122247.C731_3574	1.056e-160	512.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,23291@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_6964218_2	1090319.KE386571_gene3284	3.937e-58	214.0	COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,2TSUQ@28211|Alphaproteobacteria,2K0GU@204457|Sphingomonadales	204457|Sphingomonadales	O	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
PYH2_k127_6964218_0	1286631.X805_07550	3.962e-239	755.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,1KKB8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
PYH2_k127_6964218_1	1265502.KB905932_gene1921	6.374e-225	704.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,4ACJH@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
PYH2_k127_698138_6	1265502.KB905932_gene1927	2.823e-54	194.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria,2VRED@28216|Betaproteobacteria,4ADYC@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
PYH2_k127_698138_1	365046.Rta_05640	1.111e-238	740.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHD3@28216|Betaproteobacteria,4A9Q4@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM acyl-CoA dehydrogenase domain protein	ivd	-	1.3.8.4	ko:K00253	ko00280,ko01100,map00280,map01100	M00036	R04095	RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_698138_4	864051.BurJ1DRAFT_0508	1.166e-110	361.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VIBS@28216|Betaproteobacteria,1KJR5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Pro_CA
PYH2_k127_698138_0	1265502.KB905932_gene1925	3.812e-320	986.0	COG4579@1|root,COG4579@2|Bacteria,1MVRB@1224|Proteobacteria,2VJMA@28216|Betaproteobacteria,4ABTR@80864|Comamonadaceae	28216|Betaproteobacteria	F	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation	aceK	-	2.7.11.5	ko:K00906	-	-	-	-	ko00000,ko01000	-	-	-	AceK
PYH2_k127_698138_5	864051.BurJ1DRAFT_0510	4.816e-73	251.0	29A26@1|root,2ZX3K@2|Bacteria,1RFE8@1224|Proteobacteria,2VRJJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_698138_2	983917.RGE_43520	1.092e-209	656.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VH4C@28216|Betaproteobacteria,1KJCD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_698138_7	395495.Lcho_4206	0.0003759	49.0	COG1280@1|root,COG1280@2|Bacteria,1MWA1@1224|Proteobacteria,2VNUR@28216|Betaproteobacteria,1KMA4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Lysine exporter protein LysE	leuE_1	-	-	ko:K11250	-	-	-	-	ko00000,ko02000	2.A.76.1.5	-	-	LysE
PYH2_k127_698138_3	864051.BurJ1DRAFT_0513	3.238e-127	410.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,1KIW7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_7011329_3	983917.RGE_37730	4.191e-51	185.0	COG2199@1|root,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	2.7.7.65	ko:K21021	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,PAS_4,PAS_9
PYH2_k127_7011329_6	1157708.KB907458_gene1860	1.364e-14	78.0	COG5487@1|root,COG5487@2|Bacteria,1NGAH@1224|Proteobacteria,2VXNN@28216|Betaproteobacteria,4AFXM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
PYH2_k127_7011329_0	614083.AWQR01000005_gene1112	2.715e-156	505.0	COG4585@1|root,COG5278@1|root,COG4585@2|Bacteria,COG5278@2|Bacteria,1MWPN@1224|Proteobacteria,2VJR2@28216|Betaproteobacteria,4ABHZ@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	vsrA	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	CHASE3,HATPase_c,HisKA_3
PYH2_k127_7011329_1	338969.Rfer_1873	1.844e-112	366.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VHQ0@28216|Betaproteobacteria,4ACM6@80864|Comamonadaceae	28216|Betaproteobacteria	K	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH2_k127_7011329_2	864051.BurJ1DRAFT_1100	1.121e-53	196.0	COG2197@1|root,COG2197@2|Bacteria,1NDQC@1224|Proteobacteria,2VRW4@28216|Betaproteobacteria,1KNSS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PYH2_k127_7011329_5	296591.Bpro_0109	1.141e-31	126.0	COG3115@1|root,COG3115@2|Bacteria,1QWGJ@1224|Proteobacteria,2WGZ3@28216|Betaproteobacteria,4AH94@80864|Comamonadaceae	28216|Betaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7011329_4	338969.Rfer_3394	5.847e-51	181.0	COG3115@1|root,COG3115@2|Bacteria,1QWGJ@1224|Proteobacteria,2WGZ3@28216|Betaproteobacteria,4AH94@80864|Comamonadaceae	28216|Betaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7039022_3	987059.RBXJA2T_04053	4.066e-74	254.0	COG1305@1|root,COG1305@2|Bacteria,1MVMI@1224|Proteobacteria,2VH3S@28216|Betaproteobacteria,1KK4X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,Transglut_core
PYH2_k127_7039022_0	1265502.KB905936_gene2702	2.912e-276	853.0	COG2308@1|root,COG2308@2|Bacteria,1MUAD@1224|Proteobacteria,2VI55@28216|Betaproteobacteria,4ABXM@80864|Comamonadaceae	28216|Betaproteobacteria	S	Circularly permuted ATP-grasp type 2	-	-	-	-	-	-	-	-	-	-	-	-	CP_ATPgrasp_2
PYH2_k127_7039022_1	987059.RBXJA2T_04043	4.59e-170	541.0	COG2307@1|root,COG2307@2|Bacteria,1MVZK@1224|Proteobacteria,2VIB5@28216|Betaproteobacteria,1KJY3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E
PYH2_k127_7039022_2	864051.BurJ1DRAFT_2801	8.702e-131	428.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2VJGZ@28216|Betaproteobacteria,1KK54@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Lytic murein transglycosylase B	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
PYH2_k127_7057366_0	395495.Lcho_0523	5.224e-203	636.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,1KJRM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PYH2_k127_7057366_1	358220.C380_03760	4.164e-162	515.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,4AANC@80864|Comamonadaceae	28216|Betaproteobacteria	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
PYH2_k127_7057366_2	987059.RBXJA2T_14256	5.439e-64	224.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,1KKBH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
PYH2_k127_7057613_7	595537.Varpa_1321	6.34e-65	225.0	COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2VH2P@28216|Betaproteobacteria,4A9RF@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
PYH2_k127_7057613_3	398578.Daci_0575	5.085e-113	372.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VJNG@28216|Betaproteobacteria,4ADN9@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_7057613_4	859657.RPSI07_0959	1.073e-74	262.0	COG0697@1|root,COG0697@2|Bacteria,1MZQM@1224|Proteobacteria,2VI5H@28216|Betaproteobacteria,1K0M9@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	Drug metabolite transporter (DMT) superfamily	yijE_1	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_7057613_1	420662.Mpe_A2577	1.377e-262	816.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2VHQD@28216|Betaproteobacteria,1KNDM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_7057613_6	338969.Rfer_3849	3.488e-70	245.0	COG1278@1|root,COG1544@1|root,COG1278@2|Bacteria,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,4AHJK@80864|Comamonadaceae	28216|Betaproteobacteria	J	'Cold-shock' DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
PYH2_k127_7057613_0	338969.Rfer_0863	2.895e-310	974.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHII@28216|Betaproteobacteria,4AJXE@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding	-	-	1.3.99.16	ko:K00256	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH2_k127_7057613_5	338969.Rfer_0864	1.08e-70	243.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VRBT@28216|Betaproteobacteria,4AE1V@80864|Comamonadaceae	28216|Betaproteobacteria	C	2Fe-2S -binding domain protein	iorA	-	1.17.2.1	ko:K18029	ko00760,ko01120,map00760,map01120	M00622	R09473	RC00589	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_7057613_8	1123371.ATXH01000003_gene1941	5.31e-52	199.0	COG2930@1|root,COG2930@2|Bacteria,2GI8Q@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
PYH2_k127_7057613_2	595537.Varpa_4397	3.894e-166	526.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2VJSC@28216|Betaproteobacteria,4AD30@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM SMP-30 Gluconolaconase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
PYH2_k127_7057613_9	177439.DP2467	1.737e-49	187.0	COG3021@1|root,COG3021@2|Bacteria,1MVPP@1224|Proteobacteria,42TM7@68525|delta/epsilon subdivisions,2WS2K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
PYH2_k127_7078382_4	1265502.KB905941_gene2905	8.548e-291	916.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4ABCW@80864|Comamonadaceae	28216|Betaproteobacteria	T	ATP-binding region, ATPase domain protein	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
PYH2_k127_7078382_2	420662.Mpe_A3187	7.213e-301	941.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,1KJWM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NT	Type IV pili methyl-accepting chemotaxis transducer N-term	pilJ	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
PYH2_k127_7078382_37	1265502.KB905941_gene2907	3.53e-56	201.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,4ADYW@80864|Comamonadaceae	28216|Betaproteobacteria	NT	PFAM CheW domain protein	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
PYH2_k127_7078382_35	864051.BurJ1DRAFT_4238	5.071e-61	212.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,1KKZF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KT	PFAM response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
PYH2_k127_7078382_32	1265502.KB905941_gene2909	4.225e-68	233.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria,4ADYR@80864|Comamonadaceae	28216|Betaproteobacteria	T	response regulator, receiver	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
PYH2_k127_7078382_41	864051.BurJ1DRAFT_4240	2.492e-31	122.0	COG1773@1|root,COG1773@2|Bacteria,1N731@1224|Proteobacteria,2VVP4@28216|Betaproteobacteria,1KMIY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	rubredoxin	rubA	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
PYH2_k127_7078382_22	1286631.X805_18440	7.889e-122	400.0	COG0351@1|root,COG0351@2|Bacteria,1QUEP@1224|Proteobacteria,2WEGK@28216|Betaproteobacteria,1KKCE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
PYH2_k127_7078382_9	864051.BurJ1DRAFT_4242	6.858e-223	698.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,1KJX3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_7078382_20	987059.RBXJA2T_07140	1.428e-139	452.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,1KN35@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	dppF	-	-	ko:K12372	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH2_k127_7078382_15	987059.RBXJA2T_07135	2.051e-158	505.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,1KMZ4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K12371	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH2_k127_7078382_19	864051.BurJ1DRAFT_4972	4.185e-141	453.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VHX8@28216|Betaproteobacteria,1KMXX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	ABC-type dipeptide oligopeptide nickel transport system, permease component	-	-	-	ko:K02034,ko:K12370	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH2_k127_7078382_12	983917.RGE_11010	1.263e-191	602.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VHND@28216|Betaproteobacteria,1KPHP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K12369	ko02010,map02010	M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_7078382_3	864051.BurJ1DRAFT_4970	5.346e-295	912.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VJWW@28216|Betaproteobacteria,1KN2C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	dppA	-	-	ko:K02035,ko:K12368	ko02010,ko02024,ko02030,map02010,map02024,map02030	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH2_k127_7078382_18	399795.CtesDRAFT_PD4020	7.199e-142	458.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,4ABRW@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
PYH2_k127_7078382_6	864051.BurJ1DRAFT_4243	1.148e-235	746.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,1KJCV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PYH2_k127_7078382_30	395495.Lcho_3978	1.616e-79	270.0	COG3150@1|root,COG3150@2|Bacteria,1MVJF@1224|Proteobacteria,2VRCD@28216|Betaproteobacteria,1KKK4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0227)	yqiA	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
PYH2_k127_7078382_23	864051.BurJ1DRAFT_4245	1.046e-120	393.0	COG1028@1|root,COG1028@2|Bacteria,1N907@1224|Proteobacteria,2VJ81@28216|Betaproteobacteria,1KJSH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	Short-chain dehydrogenase reductase SDR	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_7078382_1	864051.BurJ1DRAFT_4246	3.497e-320	992.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,1KIW8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	RNB	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
PYH2_k127_7078382_24	983917.RGE_42200	2.247e-108	358.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,1KJAB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
PYH2_k127_7078382_25	1286631.X805_18220	1.532e-106	357.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,1KKDH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
PYH2_k127_7078382_27	395495.Lcho_3982	2.724e-98	332.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,1KJAT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
PYH2_k127_7078382_34	395495.Lcho_3983	4.922e-62	222.0	2DBKI@1|root,2Z9TC@2|Bacteria,1N3UD@1224|Proteobacteria,2WH5C@28216|Betaproteobacteria,1KPD2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7078382_39	1265502.KB905932_gene1864	2.355e-41	162.0	COG0526@1|root,COG0526@2|Bacteria,1MZ5J@1224|Proteobacteria,2VU93@28216|Betaproteobacteria,4ADYS@80864|Comamonadaceae	28216|Betaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
PYH2_k127_7078382_36	420662.Mpe_A3206	5.501e-59	210.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,1KKUJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
PYH2_k127_7078382_5	420662.Mpe_A3207	6.633e-269	831.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,1KJKR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Biotin carboxylase	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
PYH2_k127_7078382_26	987059.RBXJA2T_11758	7.513e-105	351.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,1KJ9A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
PYH2_k127_7078382_33	420662.Mpe_A3209	1.81e-66	240.0	2A4J7@1|root,30APC@2|Bacteria,1QVHR@1224|Proteobacteria,2VX8G@28216|Betaproteobacteria,1KKW8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TIGRFAM MJ0042 family finger-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_5
PYH2_k127_7078382_16	1265502.KB905932_gene1870	9.638e-144	461.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,4AB09@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM PfkB domain protein	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PYH2_k127_7078382_43	420662.Mpe_A3212	1.232e-20	95.0	2ANGV@1|root,31DFK@2|Bacteria,1RJ5C@1224|Proteobacteria,2VSDR@28216|Betaproteobacteria,1KM8N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	hctB	-	-	ko:K11275	-	-	-	-	ko00000,ko03036	-	-	-	HC2
PYH2_k127_7078382_10	420662.Mpe_A3213	4.218e-220	686.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,1KIUU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
PYH2_k127_7078382_0	420662.Mpe_A3214	0.0	1590.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,1KIWA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
PYH2_k127_7078382_29	983917.RGE_42330	5.75e-80	271.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,1KKNN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Negative regulator of	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
PYH2_k127_7078382_21	75379.Tint_0523	3.413e-136	452.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,1KK0F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
PYH2_k127_7078382_13	1265502.KB905932_gene1876	1.497e-181	587.0	COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,2WGR4@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
PYH2_k127_7078382_44	477228.YO5_07362	6.287e-09	63.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,1SGHN@1236|Gammaproteobacteria,1Z3D9@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
PYH2_k127_7078382_28	1265502.KB905932_gene1878	1.648e-89	304.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,4A9WR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Cytochrome C assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
PYH2_k127_7078382_8	864051.BurJ1DRAFT_4308	2.614e-230	719.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,1KJF8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
PYH2_k127_7078382_38	395495.Lcho_0375	2.472e-50	187.0	2BYGQ@1|root,32R3D@2|Bacteria,1QEGG@1224|Proteobacteria,2VT4X@28216|Betaproteobacteria,1KMA6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726
PYH2_k127_7078382_17	420662.Mpe_A3222	2.417e-142	458.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,1KJTF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
PYH2_k127_7078382_40	1265502.KB905933_gene2010	3.846e-40	153.0	2EEJ7@1|root,338D7@2|Bacteria,1NCQP@1224|Proteobacteria,2VWTW@28216|Betaproteobacteria,4AFS6@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7078382_7	1265502.KB905933_gene2009	2.394e-231	724.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,4ABG0@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
PYH2_k127_7078382_42	983917.RGE_42420	1.913e-22	99.0	2ECC1@1|root,336AE@2|Bacteria,1N89B@1224|Proteobacteria,2VXK8@28216|Betaproteobacteria,1KMMY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7078382_11	864051.BurJ1DRAFT_4369	4.12e-193	610.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,1KKAQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
PYH2_k127_7078382_14	983917.RGE_42440	2.526e-165	528.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,1KJST@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
PYH2_k127_7078382_31	987059.RBXJA2T_11668	1.858e-68	241.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria,1KK3Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
PYH2_k127_712138_1	113395.AXAI01000001_gene3373	5.55e-137	441.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TV11@28211|Alphaproteobacteria,3JWJD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	6.3.5.6,6.3.5.7	ko:K02433,ko:K21801	ko00380,ko00970,ko01100,map00380,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH2_k127_712138_3	1265502.KB905932_gene1915	1.044e-48	191.0	COG0607@1|root,COG0607@2|Bacteria,1RHQZ@1224|Proteobacteria,2VRMK@28216|Betaproteobacteria,4AEPK@80864|Comamonadaceae	28216|Betaproteobacteria	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PYH2_k127_712138_2	1054213.HMPREF9946_02315	3.313e-49	181.0	COG2318@1|root,COG2318@2|Bacteria,1R974@1224|Proteobacteria,2U4ZA@28211|Alphaproteobacteria,2JWDS@204441|Rhodospirillales	204441|Rhodospirillales	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
PYH2_k127_712138_0	290397.Adeh_2791	5.706e-206	649.0	COG0493@1|root,COG0543@1|root,COG1633@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,COG1633@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WKB4@28221|Deltaproteobacteria,2YTUD@29|Myxococcales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
PYH2_k127_7194992_0	1380394.JADL01000011_gene3977	6.283e-138	451.0	COG0404@1|root,COG0446@1|root,COG0404@2|Bacteria,COG0446@2|Bacteria,1MVEK@1224|Proteobacteria,2TTD7@28211|Alphaproteobacteria,2JR1W@204441|Rhodospirillales	204441|Rhodospirillales	E	2Fe-2S iron-sulfur cluster binding domain	-	-	1.5.99.5	ko:K22086	ko00680,ko01120,map00680,map01120	-	R00609	RC00190,RC00557	ko00000,ko00001,ko01000	-	-	-	FAD_oxidored,Fer2_4,GCV_T,GCV_T_C,Pyr_redox_2
PYH2_k127_7194992_3	285514.JNWO01000007_gene3499	4.02e-21	101.0	COG4583@1|root,COG4583@2|Bacteria,2HJE7@201174|Actinobacteria	201174|Actinobacteria	E	Sarcosine oxidase, gamma subunit	soxG	-	1.5.3.1	ko:K00305	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	SoxG
PYH2_k127_7194992_1	1238182.C882_3625	4.574e-136	447.0	COG2079@1|root,COG2079@2|Bacteria,1R5UM@1224|Proteobacteria,2U1F8@28211|Alphaproteobacteria,2JTNS@204441|Rhodospirillales	204441|Rhodospirillales	S	MmgE/PrpD family	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
PYH2_k127_7194992_2	1458357.BG58_22130	2.137e-80	271.0	COG1732@1|root,COG1732@2|Bacteria,1MV9N@1224|Proteobacteria,2VMNF@28216|Betaproteobacteria,1K54P@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycine betaine ABC transporter substrate-binding protein	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
PYH2_k127_7196237_3	316057.RPD_1509	1.002e-07	54.0	COG3302@1|root,COG3302@2|Bacteria,1N8SU@1224|Proteobacteria,2US30@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	-	-	-	ko:K18363	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	DmsC
PYH2_k127_7196237_0	316055.RPE_0981	7.246e-178	570.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2TRVF@28211|Alphaproteobacteria,3K64X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
PYH2_k127_7196237_2	316057.RPD_1525	1.091e-69	242.0	COG2080@1|root,COG2080@2|Bacteria,1MWA6@1224|Proteobacteria,2TS73@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	MA20_13960	-	1.2.5.3,1.3.7.9	ko:K03518,ko:K04107	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316,R11168	RC00490,RC02800	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_7196237_1	1187851.A33M_3188	8.791e-147	477.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TWGU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3,1.3.7.9	ko:K03520,ko:K04108	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316,R11168	RC00490,RC02800	ko00000,ko00001,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH2_k127_7204232_6	93220.LV28_05745	3.721e-09	57.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2VINH@28216|Betaproteobacteria,1K6TB@119060|Burkholderiaceae	28216|Betaproteobacteria	C	FAD binding domain	-	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2
PYH2_k127_7204232_2	1094980.Mpsy_0015	4.652e-100	344.0	COG2133@1|root,COG3794@1|root,arCOG10180@1|root,arCOG02796@2157|Archaea,arCOG02929@2157|Archaea,arCOG10180@2157|Archaea,2XT1Q@28890|Euryarchaeota,2NADP@224756|Methanomicrobia	224756|Methanomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
PYH2_k127_7204232_5	522306.CAP2UW1_4074	4.842e-18	93.0	COG2331@1|root,COG2331@2|Bacteria,1PVEY@1224|Proteobacteria,2VYJG@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
PYH2_k127_7204232_1	358220.C380_11800	2.479e-143	460.0	COG2513@1|root,COG2513@2|Bacteria,1N4VT@1224|Proteobacteria,2VI8S@28216|Betaproteobacteria,4ACX9@80864|Comamonadaceae	28216|Betaproteobacteria	G	Isocitrate lyase and phosphorylmutase	-	-	5.4.2.9	ko:K01841	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R00661	RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
PYH2_k127_7204232_0	864051.BurJ1DRAFT_3288	8.663e-179	565.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,2VI56@28216|Betaproteobacteria,1KKGG@119065|unclassified Burkholderiales	1224|Proteobacteria	F	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
PYH2_k127_7204232_4	1299327.I546_5559	3.239e-26	111.0	COG3415@1|root,COG3415@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07494	-	-	-	-	ko00000	-	-	-	DDE_3,HTH_23,HTH_28,HTH_29,HTH_32,LZ_Tnp_IS481
PYH2_k127_7204232_3	1299327.I546_5558	4.331e-82	280.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria,23B0M@1762|Mycobacteriaceae	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
PYH2_k127_7208731_0	262724.TT_P0211	5.206e-124	409.0	COG1373@1|root,COG1373@2|Bacteria,1WJIW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PYH2_k127_7208731_1	2074.JNYD01000015_gene4604	1.345e-65	237.0	COG3848@1|root,COG3848@2|Bacteria,2H2J1@201174|Actinobacteria	201174|Actinobacteria	T	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers
PYH2_k127_7212323_0	864051.BurJ1DRAFT_3572	2.981e-286	887.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,1KJNP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
PYH2_k127_7212323_2	420662.Mpe_A1621	8.601e-189	599.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VKJ3@28216|Betaproteobacteria,1KIWH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1
PYH2_k127_7212323_1	987059.RBXJA2T_14696	1.975e-267	828.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,1KIYR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
PYH2_k127_7212323_6	864051.BurJ1DRAFT_3575	6.296e-34	138.0	2BCK1@1|root,32662@2|Bacteria,1RHH4@1224|Proteobacteria,2VSPG@28216|Betaproteobacteria,1KMDU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
PYH2_k127_7212323_7	159450.NH14_23015	2e-13	76.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,1K8F3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
PYH2_k127_7212323_4	1538295.JY96_00050	1.628e-62	218.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,1KKXZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	cyclase dehydrase	ratA	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
PYH2_k127_7212323_3	864051.BurJ1DRAFT_3578	2.293e-74	252.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,1KKJN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
PYH2_k127_7212323_5	395495.Lcho_2056	3.395e-43	160.0	COG0626@1|root,COG0626@2|Bacteria,1MU9E@1224|Proteobacteria,2VHNW@28216|Betaproteobacteria,1KJ3A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
PYH2_k127_7252675_1	1123229.AUBC01000013_gene2611	2.015e-75	265.0	COG0154@1|root,COG0410@1|root,COG0154@2|Bacteria,COG0410@2|Bacteria,1MUVQ@1224|Proteobacteria,2TU7H@28211|Alphaproteobacteria,3JSWU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	ABC_tran,Amidase
PYH2_k127_7252675_0	314262.MED193_19919	1.234e-85	290.0	COG4674@1|root,COG4674@2|Bacteria,1PHYH@1224|Proteobacteria,2TVYS@28211|Alphaproteobacteria,2P5A5@2433|Roseobacter	28211|Alphaproteobacteria	S	ABC-type transport system, ATPase component	-	-	-	ko:K01995,ko:K11962	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_7257076_4	420662.Mpe_A0181	1.102e-21	96.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,1KJ0G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PYH2_k127_7257076_1	983917.RGE_02430	1.16e-93	313.0	29SCQ@1|root,30DHC@2|Bacteria,1RGDC@1224|Proteobacteria,2VSB9@28216|Betaproteobacteria,1KKY4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7257076_0	1286631.X805_03690	1.226e-106	351.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VH8F@28216|Betaproteobacteria,1KJ58@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
PYH2_k127_7257076_2	864051.BurJ1DRAFT_0299	2.038e-32	138.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VH8F@28216|Betaproteobacteria,1KJ58@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
PYH2_k127_7257076_3	338969.Rfer_3728	3.996e-27	114.0	COG0697@1|root,COG0697@2|Bacteria,1MVHN@1224|Proteobacteria,2VI21@28216|Betaproteobacteria,4AD5E@80864|Comamonadaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_7284945_1	522306.CAP2UW1_0229	1.225e-06	51.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,1KR44@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
PYH2_k127_7284945_0	395495.Lcho_3744	0.0	1675.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,1KJIC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
PYH2_k127_7284945_2	1458357.BG58_16485	2.281e-05	51.0	COG1226@1|root,COG1226@2|Bacteria,1QY40@1224|Proteobacteria,2VUSI@28216|Betaproteobacteria,1K5RQ@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2
PYH2_k127_7296930_6	864051.BurJ1DRAFT_3323	2.029e-96	321.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,1KKQX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
PYH2_k127_7296930_2	864051.BurJ1DRAFT_3324	2.466e-175	556.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,2VK76@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
PYH2_k127_7296930_4	864051.BurJ1DRAFT_3325	2.704e-122	398.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
PYH2_k127_7296930_10	864051.BurJ1DRAFT_3326	2.095e-40	156.0	2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7296930_0	864051.BurJ1DRAFT_3327	0.0	1132.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,1KKEG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADPH-dependent glutamate synthase beta	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
PYH2_k127_7296930_1	864051.BurJ1DRAFT_3329	5.517e-281	868.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria,1KN5P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Fe-S oxidoreductase	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
PYH2_k127_7296930_5	864051.BurJ1DRAFT_3330	1.112e-113	373.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
PYH2_k127_7296930_8	864051.BurJ1DRAFT_3331	5.57e-56	208.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2VSFJ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
PYH2_k127_7296930_11	1123393.KB891316_gene1847	4.007e-33	130.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria,1KT55@119069|Hydrogenophilales	119069|Hydrogenophilales	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
PYH2_k127_7296930_9	864051.BurJ1DRAFT_3333	1.213e-55	196.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,2VSQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Sulfur relay protein TusC DsrF	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
PYH2_k127_7296930_7	864051.BurJ1DRAFT_3334	1.702e-62	216.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,2VR8N@28216|Betaproteobacteria	28216|Betaproteobacteria	P	sulfur relay protein TusD DsrE	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
PYH2_k127_7296930_3	864051.BurJ1DRAFT_3335	2.564e-122	392.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
PYH2_k127_7307610_1	443598.AUFA01000127_gene7209	4.903e-16	80.0	COG2984@1|root,COG2984@2|Bacteria,1RDUT@1224|Proteobacteria,2U8XC@28211|Alphaproteobacteria,3JYZA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_7307610_0	395495.Lcho_2118	1.902e-258	803.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,1KJ65@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Carboxyl transferase domain	accB	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
PYH2_k127_7310464_3	987059.RBXJA2T_08023	1.548e-17	85.0	29XD7@1|root,30J34@2|Bacteria,1PQBQ@1224|Proteobacteria,2W9N2@28216|Betaproteobacteria,1KMS3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7310464_1	420662.Mpe_A2009	6.755e-192	603.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2VHQX@28216|Betaproteobacteria,1KJD6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	AFG1-like ATPase	yhcM	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
PYH2_k127_7310464_0	987059.RBXJA2T_08013	6.648e-247	775.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,1KJ4Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase	odhL	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
PYH2_k127_7310464_2	987059.RBXJA2T_08003	1.653e-146	466.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,1KIX4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH2_k127_7331770_0	1265502.KB905940_gene2956	2.911e-320	994.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,4AB5A@80864|Comamonadaceae	28216|Betaproteobacteria	S	peptidase S45, penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
PYH2_k127_7331770_7	983917.RGE_14860	5.692e-60	211.0	COG1522@1|root,COG1522@2|Bacteria,1MXVU@1224|Proteobacteria,2VRE2@28216|Betaproteobacteria,1KMAE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix ASNC type	lrp	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
PYH2_k127_7331770_1	983917.RGE_14870	7.795e-198	623.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,1KMYC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Aminotransferase class-III	rocD	-	2.6.1.13	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R00667	RC00006,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_3,Arginase
PYH2_k127_7331770_6	864051.BurJ1DRAFT_0606	2.684e-119	387.0	COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,2VNIW@28216|Betaproteobacteria	28216|Betaproteobacteria	ET	belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PYH2_k127_7331770_4	296591.Bpro_0402	8.849e-122	395.0	COG0765@1|root,COG0765@2|Bacteria,1QN80@1224|Proteobacteria,2VKTN@28216|Betaproteobacteria,4ACMV@80864|Comamonadaceae	28216|Betaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
PYH2_k127_7331770_3	864051.BurJ1DRAFT_0604	4.682e-122	411.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2VHIC@28216|Betaproteobacteria,1KK1S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
PYH2_k127_7331770_5	1223521.BBJX01000002_gene2653	1.538e-121	414.0	COG2911@1|root,COG2911@2|Bacteria,1NHQB@1224|Proteobacteria,2VN2Q@28216|Betaproteobacteria,4ABVZ@80864|Comamonadaceae	28216|Betaproteobacteria	S	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_2
PYH2_k127_7331770_2	388051.AUFE01000057_gene4922	4.434e-162	524.0	COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2VN2I@28216|Betaproteobacteria	28216|Betaproteobacteria	E	peptidase dimerisation domain protein	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
PYH2_k127_7331770_8	232721.Ajs_1711	3.268e-24	110.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VI90@28216|Betaproteobacteria,4A9Y2@80864|Comamonadaceae	28216|Betaproteobacteria	C	alcohol dehydrogenase	gbd1	-	1.1.1.1,1.1.1.61	ko:K00043,ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00071,map00350,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01200,map01220	-	R00623,R00754,R01644,R04880,R05233,R05234,R06917,R06927	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
PYH2_k127_7341985_1	1265313.HRUBRA_00321	7.331e-61	220.0	COG1252@1|root,COG1252@2|Bacteria,1MX96@1224|Proteobacteria,1RM9I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH dehydrogenase	ndh	GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0036094,GO:0042592,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044464,GO:0045333,GO:0048037,GO:0048878,GO:0050136,GO:0050660,GO:0050662,GO:0050801,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:0098771,GO:0098796,GO:1901265,GO:1901363,GO:1902494	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iECIAI39_1322.ECIAI39_2051,iPC815.YPO1617	Pyr_redox_2
PYH2_k127_7341985_2	748247.AZKH_2010	1.196e-20	98.0	2AF6U@1|root,3155S@2|Bacteria,1PV6C@1224|Proteobacteria,2WB41@28216|Betaproteobacteria,2KZ86@206389|Rhodocyclales	206389|Rhodocyclales	S	Glycine zipper 2TM domain	-	-	-	ko:K04062	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
PYH2_k127_7341985_0	502025.Hoch_5996	1.112e-67	238.0	COG1075@1|root,COG1075@2|Bacteria,1QTCH@1224|Proteobacteria,437VW@68525|delta/epsilon subdivisions,2WYPR@28221|Deltaproteobacteria,2YUCF@29|Myxococcales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7388424_0	983917.RGE_34660	9.084e-304	946.0	COG2307@1|root,COG2308@1|root,COG2307@2|Bacteria,COG2308@2|Bacteria,1MX5P@1224|Proteobacteria,2VJEU@28216|Betaproteobacteria,1KJV9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	A predicted alpha-helical domain with a conserved ER motif.	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-E,CP_ATPgrasp_2
PYH2_k127_7389966_1	864051.BurJ1DRAFT_3124	2.711e-138	445.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,2VHFX@28216|Betaproteobacteria,1KJC5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	RNA-metabolising metallo-beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,RMMBL
PYH2_k127_7389966_4	864051.BurJ1DRAFT_3125	7.773e-42	162.0	2FEFF@1|root,346F4@2|Bacteria,1NZUX@1224|Proteobacteria,2W4QF@28216|Betaproteobacteria,1KNVR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7389966_3	402626.Rpic_1248	1.784e-121	399.0	COG1804@1|root,COG1804@2|Bacteria,1MW1H@1224|Proteobacteria,2VJBJ@28216|Betaproteobacteria,1KGIS@119060|Burkholderiaceae	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH2_k127_7389966_2	395495.Lcho_2651	8.504e-131	424.0	COG3751@1|root,COG3751@2|Bacteria,1NG7K@1224|Proteobacteria,2VK5Y@28216|Betaproteobacteria,1KJ8U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Prolyl 4-hydroxylase alpha subunit homologues.	-	-	1.14.11.2	ko:K00472	ko00330,ko01100,map00330,map01100	-	R01252	RC00478	ko00000,ko00001,ko01000	-	-	-	2OG-FeII_Oxy_3
PYH2_k127_7389966_0	983917.RGE_13120	0.0	1463.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,1KJT4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
PYH2_k127_739230_3	864051.BurJ1DRAFT_4523	1.28e-105	352.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,2VIM5@28216|Betaproteobacteria,1KJWJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PYH2_k127_739230_5	983917.RGE_14830	1.526e-53	194.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,1KNN8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
PYH2_k127_739230_0	864051.BurJ1DRAFT_4521	7.78e-157	505.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKQJ@28216|Betaproteobacteria,1KKBI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_739230_1	983917.RGE_14850	2.548e-139	465.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,1KK8I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Tyrosine recombinase XerD	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PYH2_k127_739230_6	983917.RGE_23960	7.205e-31	123.0	2CHW3@1|root,32S6N@2|Bacteria,1N0I3@1224|Proteobacteria,2VW65@28216|Betaproteobacteria,1KMGW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pathogenicity locus	mcrB	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	Cdd1
PYH2_k127_739230_2	983917.RGE_23970	8.371e-115	374.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VHTZ@28216|Betaproteobacteria,1KJT0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
PYH2_k127_739230_4	1265502.KB905963_gene397	5.559e-102	340.0	COG0252@1|root,COG0252@2|Bacteria,1MWIR@1224|Proteobacteria,2VJI2@28216|Betaproteobacteria,4AAGM@80864|Comamonadaceae	28216|Betaproteobacteria	EJ	PFAM Asparaginase glutaminase	ansB	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
PYH2_k127_739230_7	983917.RGE_24010	2.098e-19	89.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,1KIZX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PYH2_k127_7398630_4	986075.CathTA2_0425	1.834e-46	173.0	COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli	91061|Bacilli	J	Belongs to the amidase family	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH2_k127_7398630_1	765952.PUV_21230	2.64e-115	392.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
PYH2_k127_7398630_3	765952.PUV_21240	7.627e-64	229.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	-	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran,FtsX
PYH2_k127_7398630_0	1173028.ANKO01000111_gene4995	3.813e-123	415.0	COG0318@1|root,COG0318@2|Bacteria,1G4CE@1117|Cyanobacteria,1H8QS@1150|Oscillatoriales	1117|Cyanobacteria	IQ	Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C,PP-binding
PYH2_k127_7398630_2	861299.J421_1813	1.924e-78	269.0	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_6,Acetyltransf_9
PYH2_k127_7407936_4	1454004.AW11_02644	6.281e-44	166.0	COG2062@1|root,COG2062@2|Bacteria,1RIC8@1224|Proteobacteria,2VUGF@28216|Betaproteobacteria,1KR15@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	T	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PYH2_k127_7407936_3	1158292.JPOE01000005_gene1152	3.825e-71	253.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
PYH2_k127_7407936_5	1163617.SCD_n00048	1.15e-36	149.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2VNM5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7407936_2	269796.Rru_A1419	2.905e-107	365.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2TTSQ@28211|Alphaproteobacteria,2JWR3@204441|Rhodospirillales	204441|Rhodospirillales	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	-	-	-	-	-	-	-	-	-	UbiD
PYH2_k127_7407936_0	1265502.KB905930_gene1447	1.91e-168	539.0	COG0683@1|root,COG0683@2|Bacteria,1MVV2@1224|Proteobacteria,2VJE6@28216|Betaproteobacteria,4AB9N@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_7407936_1	397945.Aave_3173	6.903e-110	362.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2VK6C@28216|Betaproteobacteria,4ACRR@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_7418784_4	864051.BurJ1DRAFT_0667	2.146e-121	396.0	COG0697@1|root,COG0697@2|Bacteria,1MV7Y@1224|Proteobacteria,2VR8Q@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_7418784_10	748247.AZKH_3436	5.002e-27	124.0	COG3427@1|root,COG3427@2|Bacteria,1N55Y@1224|Proteobacteria,2VTZD@28216|Betaproteobacteria,2KX5B@206389|Rhodocyclales	206389|Rhodocyclales	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
PYH2_k127_7418784_12	1267533.KB906739_gene2493	1.058e-11	75.0	2E74W@1|root,331P9@2|Bacteria,3Y8XR@57723|Acidobacteria	57723|Acidobacteria	S	Protein of unknown function (DUF2490)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2490
PYH2_k127_7418784_11	1458427.BAWN01000017_gene1127	3.406e-13	78.0	COG1487@1|root,COG1487@2|Bacteria,1N9J5@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
PYH2_k127_7418784_9	177439.DP2816	3.595e-46	176.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,42TN0@68525|delta/epsilon subdivisions,2WQ75@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
PYH2_k127_7418784_7	335543.Sfum_2428	5.039e-99	337.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,42NU4@68525|delta/epsilon subdivisions,2WKV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
PYH2_k127_7418784_0	1458357.BG58_05605	0.0	1060.0	COG3243@1|root,COG3243@2|Bacteria,1MUNE@1224|Proteobacteria,2VJZW@28216|Betaproteobacteria,1K3Z3@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Protein of unknown function (DUF3141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3141
PYH2_k127_7418784_2	1454004.AW11_03031	1.485e-163	518.0	COG0280@1|root,COG0280@2|Bacteria,1QTXP@1224|Proteobacteria,2VJ4B@28216|Betaproteobacteria	28216|Betaproteobacteria	C	phosphate	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
PYH2_k127_7418784_1	322710.Avin_44030	2.291e-174	555.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
PYH2_k127_7418784_5	414684.RC1_1846	1.367e-113	371.0	COG1028@1|root,COG1028@2|Bacteria,1MU5Y@1224|Proteobacteria,2TRNQ@28211|Alphaproteobacteria,2JQYQ@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.30	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	M00088	R01361	RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short,adh_short_C2
PYH2_k127_7418784_6	864069.MicloDRAFT_00018950	1.002e-102	337.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,2TTE6@28211|Alphaproteobacteria,1JUG5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	TIGRFAM 3-oxoacid CoA-transferase, A subunit	-	-	2.8.3.8,2.8.3.9	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH2_k127_7418784_8	1040989.AWZU01000001_gene5634	1.09e-96	331.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,2TQS5@28211|Alphaproteobacteria,3JV6J@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Coenzyme A transferase	-	-	2.8.3.5,2.8.3.8,2.8.3.9	ko:K01029,ko:K01035	ko00072,ko00280,ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00072,map00280,map00310,map00627,map00640,map00650,map01100,map01120,map02020	-	R00410,R01179,R01359,R01365,R07832	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH2_k127_7418784_3	1458357.BG58_05620	7.787e-135	445.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VJQ0@28216|Betaproteobacteria,1JZNA@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI_1	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_7427921_3	748247.AZKH_p0136	2.582e-12	71.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VQCJ@28216|Betaproteobacteria,2KY98@206389|Rhodocyclales	206389|Rhodocyclales	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
PYH2_k127_7427921_2	76114.ebD5	3.234e-32	126.0	2ENWT@1|root,33GHR@2|Bacteria,1NH7H@1224|Proteobacteria,2W4MF@28216|Betaproteobacteria,2KZ6F@206389|Rhodocyclales	206389|Rhodocyclales	S	Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma)	ppcD	-	-	-	-	-	-	-	-	-	-	-	Phenyl_P_gamma
PYH2_k127_7427921_0	748247.AZKH_p0134	5.35e-303	932.0	COG0043@1|root,COG0043@2|Bacteria,1PZMY@1224|Proteobacteria,2W1PG@28216|Betaproteobacteria,2KYBP@206389|Rhodocyclales	206389|Rhodocyclales	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	ppcA	-	-	-	-	-	-	-	-	-	-	-	UbiD
PYH2_k127_7427921_1	76114.ebD6	6.24e-80	272.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,2KXX4@206389|Rhodocyclales	206389|Rhodocyclales	S	haloacid dehalogenase-like hydrolase	ppcC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
PYH2_k127_7483661_4	864051.BurJ1DRAFT_1136	5.932e-46	169.0	COG3203@1|root,COG3203@2|Bacteria,1R5T2@1224|Proteobacteria,2VMH6@28216|Betaproteobacteria,1KPGF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Gram-negative porin	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
PYH2_k127_7483661_2	864051.BurJ1DRAFT_1135	2.831e-76	262.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,1KKP3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
PYH2_k127_7483661_3	1265502.KB905948_gene1000	9.566e-68	233.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,4ADIX@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
PYH2_k127_7483661_0	1265502.KB905948_gene1001	3.099e-258	804.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,4ABVC@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
PYH2_k127_7483661_1	864051.BurJ1DRAFT_1132	3.132e-155	501.0	COG2038@1|root,COG2038@2|Bacteria,1R4EY@1224|Proteobacteria,2VPTK@28216|Betaproteobacteria,1KJFY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Phosphoribosyltransferase	-	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
PYH2_k127_7501079_2	384765.SIAM614_28362	8.451e-122	396.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PYH2_k127_7501079_4	84531.JMTZ01000038_gene3588	6.53e-07	53.0	2EFPP@1|root,339FP@2|Bacteria,1NA60@1224|Proteobacteria,1SH3I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
PYH2_k127_7501079_6	1054213.HMPREF9946_03165	7.344e-05	45.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria	1224|Proteobacteria	L	nuclease	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
PYH2_k127_7501079_5	1169154.KB897777_gene3520	1.383e-06	55.0	COG3251@1|root,COG3251@2|Bacteria,2GQIK@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	ko:K05375	ko00261,ko01130,map00261,map01130	M00736	R10880	RC00064,RC00141,RC03296,RC03297,RC03298	ko00000,ko00001,ko00002	-	-	-	MbtH
PYH2_k127_7501079_3	570967.JMLV01000007_gene875	3.07e-94	324.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2TSQI@28211|Alphaproteobacteria,2JPPT@204441|Rhodospirillales	204441|Rhodospirillales	E	FAD dependent oxidoreductase	-	-	1.4.5.1	ko:K00285	ko00360,map00360	-	R01374,R09493	RC00006,RC00025	ko00000,ko00001,ko01000	-	-	-	DAO
PYH2_k127_7501079_0	1502851.FG93_05266	8.541e-193	606.0	COG0687@1|root,COG0687@2|Bacteria,1MU0I@1224|Proteobacteria,2TSJT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Spermidine putrescine-binding periplasmic protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
PYH2_k127_7501079_1	1380394.JADL01000001_gene2372	3.299e-135	464.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,2JQQC@204441|Rhodospirillales	204441|Rhodospirillales	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
PYH2_k127_7502028_3	1123229.AUBC01000012_gene2693	6.276e-53	194.0	COG1653@1|root,COG1653@2|Bacteria,1R4UG@1224|Proteobacteria,2TUMF@28211|Alphaproteobacteria,3JWW5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
PYH2_k127_7502028_4	189753.AXAS01000056_gene5959	2.364e-13	70.0	COG2984@1|root,COG2984@2|Bacteria,1RDUT@1224|Proteobacteria,2U8XC@28211|Alphaproteobacteria,3JYZA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_7502028_1	379066.GAU_1919	2.076e-104	345.0	COG0584@1|root,COG0584@2|Bacteria,1ZTMT@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
PYH2_k127_7502028_0	1100720.ALKN01000045_gene329	1.948e-151	488.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,2VIUC@28216|Betaproteobacteria,4AC4C@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM 2-nitropropane dioxygenase NPD	-	-	-	-	-	-	-	-	-	-	-	-	NMO
PYH2_k127_7502028_2	765911.Thivi_3235	9.905e-103	345.0	COG0661@1|root,COG0661@2|Bacteria,1MW1J@1224|Proteobacteria,1RYAY@1236|Gammaproteobacteria,1WW8Z@135613|Chromatiales	135613|Chromatiales	S	pfam abc1	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
PYH2_k127_7505002_3	864051.BurJ1DRAFT_1693	2.13e-20	94.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,2VM6W@28216|Betaproteobacteria,1KJE7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	PFAM response regulator receiver	ompR2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PYH2_k127_7505002_2	420662.Mpe_A2644	5.962e-38	152.0	COG3678@1|root,COG3678@2|Bacteria,1NBYM@1224|Proteobacteria,2VXG9@28216|Betaproteobacteria,1KMIK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NPTU	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
PYH2_k127_7505002_0	864051.BurJ1DRAFT_1691	3.809e-87	299.0	2DVPK@1|root,32UZW@2|Bacteria,1PYS7@1224|Proteobacteria,2VXY8@28216|Betaproteobacteria,1KN0G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7505002_4	1131813.AQVT01000001_gene2141	4.451e-13	78.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,1JR05@119045|Methylobacteriaceae	28211|Alphaproteobacteria	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
PYH2_k127_7505002_1	1267533.KB906733_gene3192	9.413e-58	213.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PYH2_k127_7522434_0	864051.BurJ1DRAFT_3699	4.523e-90	309.0	COG0845@1|root,COG0845@2|Bacteria,1RC4B@1224|Proteobacteria,2VSI9@28216|Betaproteobacteria,1KNGQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
PYH2_k127_7522434_1	864051.BurJ1DRAFT_3698	5.579e-40	156.0	COG0653@1|root,COG0653@2|Bacteria,1MX0P@1224|Proteobacteria,2VZG2@28216|Betaproteobacteria,1KMX1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	SecA preprotein cross-linking domain	-	-	-	-	-	-	-	-	-	-	-	-	SecA_DEAD,SecA_PP_bind
PYH2_k127_7543809_1	395495.Lcho_0238	1.15e-233	733.0	COG2176@1|root,COG2176@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,1KNCN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	LT	DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
PYH2_k127_7543809_3	365044.Pnap_3249	2.321e-153	491.0	COG1752@1|root,COG1752@2|Bacteria,1MVHW@1224|Proteobacteria,2VH3I@28216|Betaproteobacteria,4AA4W@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
PYH2_k127_7543809_5	296591.Bpro_2641	1.221e-99	331.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae	28216|Betaproteobacteria	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
PYH2_k127_7543809_0	1038869.AXAN01000063_gene4605	2.366e-301	936.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria,1K56K@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
PYH2_k127_7543809_2	358220.C380_21550	1.022e-212	675.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,2VH3E@28216|Betaproteobacteria,4AJ9Z@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
PYH2_k127_7543809_4	1095769.CAHF01000019_gene852	1.564e-111	369.0	COG4221@1|root,COG4221@2|Bacteria,1MWXS@1224|Proteobacteria,2VHSZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PYH2_k127_757004_5	420662.Mpe_A0420	1.465e-89	303.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,2VKE3@28216|Betaproteobacteria,1KJ4I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	regulatory	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PYH2_k127_757004_3	93220.LV28_13020	1.348e-105	360.0	COG1893@1|root,COG1893@2|Bacteria,1MVZ1@1224|Proteobacteria,2VJFW@28216|Betaproteobacteria,1K23R@119060|Burkholderiaceae	28216|Betaproteobacteria	H	2-dehydropantoate 2-reductase	panE2	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
PYH2_k127_757004_7	498211.CJA_0423	7.845e-25	118.0	COG1716@1|root,COG1716@2|Bacteria,1MXT7@1224|Proteobacteria,1SAKZ@1236|Gammaproteobacteria,1FG6I@10|Cellvibrio	1236|Gammaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
PYH2_k127_757004_2	864051.BurJ1DRAFT_0518	7.321e-195	618.0	COG0265@1|root,COG0265@2|Bacteria,1NXB0@1224|Proteobacteria,2VJB7@28216|Betaproteobacteria,1KN05@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
PYH2_k127_757004_4	1265502.KB905945_gene652	1.912e-104	340.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,2VKQH@28216|Betaproteobacteria,4AB9G@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
PYH2_k127_757004_0	338969.Rfer_3852	2.613e-249	775.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,4AFB1@80864|Comamonadaceae	28216|Betaproteobacteria	S	tRNA-splicing ligase RtcB	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
PYH2_k127_757004_6	338969.Rfer_3853	2.97e-57	202.0	COG1371@1|root,COG1371@2|Bacteria,1RJU0@1224|Proteobacteria,2VU90@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
PYH2_k127_757004_1	1266925.JHVX01000001_gene2629	1.798e-209	669.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2WGHZ@28216|Betaproteobacteria,37225@32003|Nitrosomonadales	28216|Betaproteobacteria	IQ	AMP-dependent synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
PYH2_k127_7585117_3	1123355.JHYO01000017_gene3613	7.498e-106	357.0	COG2010@1|root,COG2010@2|Bacteria,1REKI@1224|Proteobacteria,2UA53@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH2_k127_7585117_6	338969.Rfer_4085	4.575e-37	144.0	COG4654@1|root,COG4654@2|Bacteria,1MZJM@1224|Proteobacteria,2VV99@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Pfam cytochrome c	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
PYH2_k127_7585117_0	338969.Rfer_4073	2.758e-260	820.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,2VKG8@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7585117_5	864051.BurJ1DRAFT_3465	5.329e-72	249.0	COG2128@1|root,COG2128@2|Bacteria,1MVWP@1224|Proteobacteria,2WFTT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
PYH2_k127_7585117_2	296591.Bpro_1056	2.554e-144	466.0	COG3181@1|root,COG3181@2|Bacteria,1QVZV@1224|Proteobacteria,2VMXW@28216|Betaproteobacteria,4AAEP@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_7585117_4	1121015.N789_12855	7.663e-96	317.0	COG3369@1|root,COG3592@1|root,COG3369@2|Bacteria,COG3592@2|Bacteria,1RCN9@1224|Proteobacteria,1SZZ4@1236|Gammaproteobacteria,1X90I@135614|Xanthomonadales	135614|Xanthomonadales	S	Divergent 4Fe-4S mono-cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_19,zf-CDGSH
PYH2_k127_7585117_1	983917.RGE_43340	4.549e-173	557.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,1KJYM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Putative nucleotidyltransferase substrate binding domain	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
PYH2_k127_7592097_1	1411123.JQNH01000001_gene3179	2.407e-105	347.0	COG1250@1|root,COG1250@2|Bacteria,1MV8M@1224|Proteobacteria,2TRAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH,3HCDH_N
PYH2_k127_7592097_0	1502851.FG93_03076	1.172e-166	534.0	COG3246@1|root,COG3246@2|Bacteria,1MZTP@1224|Proteobacteria,2TQKN@28211|Alphaproteobacteria,3JS9Q@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	beta-keto acid cleavage enzyme	-	-	-	-	-	-	-	-	-	-	-	-	BKACE
PYH2_k127_7592097_2	1366050.N234_34995	9.194e-40	151.0	2E9FY@1|root,333P7@2|Bacteria,1N8S6@1224|Proteobacteria,2VWAN@28216|Betaproteobacteria,1K4AW@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7605697_0	1265502.KB905933_gene2106	0.0	1384.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria,4A9YM@80864|Comamonadaceae	28216|Betaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
PYH2_k127_7605697_1	864051.BurJ1DRAFT_1371	2.779e-71	244.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,1KK8R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
PYH2_k127_7631787_0	1286631.X805_08920	1.008e-195	615.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIA6@28216|Betaproteobacteria,1KKA9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_7631787_5	404589.Anae109_1967	1.103e-15	79.0	COG0500@1|root,COG2226@2|Bacteria,1R79J@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
PYH2_k127_7631787_3	395495.Lcho_2128	1.831e-58	213.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,2VSHT@28216|Betaproteobacteria,1KKVC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
PYH2_k127_7631787_4	864051.BurJ1DRAFT_3846	5.391e-20	94.0	COG2388@1|root,COG2388@2|Bacteria,1N8AQ@1224|Proteobacteria,2VW02@28216|Betaproteobacteria,1KMIR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
PYH2_k127_7631787_1	358220.C380_04660	5.423e-142	459.0	COG3181@1|root,COG3181@2|Bacteria,1R7W8@1224|Proteobacteria,2VP6R@28216|Betaproteobacteria,4AB7J@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_7631787_8	1120953.AUBH01000001_gene812	4.859e-05	54.0	COG3832@1|root,COG3832@2|Bacteria,1RDGX@1224|Proteobacteria,1S4FQ@1236|Gammaproteobacteria,4675R@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
PYH2_k127_7631787_6	864051.BurJ1DRAFT_3840	3.781e-12	76.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,2VRWE@28216|Betaproteobacteria,1KNRF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
PYH2_k127_7631787_2	987059.RBXJA2T_01565	1.398e-63	224.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VIE8@28216|Betaproteobacteria,1KMZ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Peptidase family M3	dcp	-	3.4.15.5	ko:K01284	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
PYH2_k127_7649126_2	1286631.X805_01930	2.567e-115	377.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,1KJ45@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
PYH2_k127_7649126_3	864051.BurJ1DRAFT_4648	1.972e-95	316.0	COG0811@1|root,COG0811@2|Bacteria,1RFIG@1224|Proteobacteria,2VN8T@28216|Betaproteobacteria,1KK0C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
PYH2_k127_7649126_5	864051.BurJ1DRAFT_4649	5.867e-43	161.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VSMV@28216|Betaproteobacteria,1KM6I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
PYH2_k127_7649126_0	1265502.KB905939_gene2336	0.0	1382.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,4A9UD@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
PYH2_k127_7649126_4	420662.Mpe_A0217	2.214e-54	201.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,1KM9B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
PYH2_k127_7649126_1	864051.BurJ1DRAFT_4654	4.543e-154	494.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,1KJ0R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
PYH2_k127_7672918_0	414684.RC1_0300	2.987e-113	372.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2TRZD@28211|Alphaproteobacteria,2JUZE@204441|Rhodospirillales	204441|Rhodospirillales	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PYH2_k127_7672918_2	1121405.dsmv_1121	1.198e-32	129.0	COG4274@1|root,COG4274@2|Bacteria,1N83R@1224|Proteobacteria,431NX@68525|delta/epsilon subdivisions,2WWPF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GYD domain	-	-	-	-	-	-	-	-	-	-	-	-	GYD
PYH2_k127_7672918_1	545264.KB898744_gene2154	1.101e-60	216.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,1RSI9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
PYH2_k127_7682204_16	439235.Dalk_3104	5.305e-39	154.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WISF@28221|Deltaproteobacteria,2MIAR@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
PYH2_k127_7682204_20	749927.AMED_4572	1.551e-05	48.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4DXSQ@85010|Pseudonocardiales	201174|Actinobacteria	C	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate	frc	-	2.8.3.15,2.8.3.16	ko:K07544,ko:K07749	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
PYH2_k127_7682204_18	1123504.JQKD01000027_gene4104	6.149e-24	102.0	COG1942@1|root,COG1942@2|Bacteria,1N8I6@1224|Proteobacteria,2VW8C@28216|Betaproteobacteria,4AFEI@80864|Comamonadaceae	28216|Betaproteobacteria	G	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
PYH2_k127_7682204_11	1123504.JQKD01000027_gene4105	7.61e-120	390.0	COG0235@1|root,COG0235@2|Bacteria,1MWP9@1224|Proteobacteria,2VKWQ@28216|Betaproteobacteria,4AHJP@80864|Comamonadaceae	28216|Betaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
PYH2_k127_7682204_1	395495.Lcho_1140	3.625e-255	794.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,2VJ4R@28216|Betaproteobacteria,1KJED@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Amidohydrolase family	atzB	-	3.5.4.32	ko:K18456	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_1
PYH2_k127_7682204_2	1504672.669784496	1.44e-249	779.0	COG2233@1|root,COG2233@2|Bacteria,1MUN9@1224|Proteobacteria,2VGZR@28216|Betaproteobacteria,4AC1E@80864|Comamonadaceae	28216|Betaproteobacteria	F	PFAM Xanthine uracil vitamin C permease	-	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
PYH2_k127_7682204_3	1286631.X805_10080	2.001e-227	708.0	COG3748@1|root,COG3748@2|Bacteria,1MWHB@1224|Proteobacteria,2VIC0@28216|Betaproteobacteria,1KJ02@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Urate oxidase N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Urate_ox_N
PYH2_k127_7682204_9	864051.BurJ1DRAFT_4050	1.967e-148	487.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VNHK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_7682204_15	1504672.669784500	1.188e-51	186.0	COG2351@1|root,COG2351@2|Bacteria,1RH84@1224|Proteobacteria,2VUG8@28216|Betaproteobacteria,4ADZY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily	uraH	-	3.5.2.17	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R06601	RC03393	ko00000,ko00001,ko00002,ko01000,ko02000	9.B.35.1.2,9.B.35.2	-	-	Transthyretin
PYH2_k127_7682204_12	864051.BurJ1DRAFT_4052	2.163e-96	322.0	COG1802@1|root,COG1802@2|Bacteria,1R96W@1224|Proteobacteria,2VIQU@28216|Betaproteobacteria,1KJ1M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_7682204_5	864051.BurJ1DRAFT_4053	3.106e-192	608.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2VJQR@28216|Betaproteobacteria,1KK5H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	deacetylase	-	-	3.5.1.41	ko:K01452	ko00520,ko01100,map00520,map01100	-	R02333	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
PYH2_k127_7682204_0	1504672.669784503	6.4e-323	1011.0	COG0624@1|root,COG3195@1|root,COG0624@2|Bacteria,COG3195@2|Bacteria,1MVUX@1224|Proteobacteria,2VIGB@28216|Betaproteobacteria,4AB68@80864|Comamonadaceae	28216|Betaproteobacteria	E	Amidase, hydantoinase carbamoylase family	uraD	-	3.5.1.6,3.5.1.87,3.5.3.9	ko:K02083,ko:K06016	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	M00046	R00905,R02423,R04666	RC00064,RC00096	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	M20_dimer,OHCU_decarbox,Peptidase_M20,Peptidase_M28
PYH2_k127_7682204_4	1504672.669784504	1.642e-220	692.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,2VK9D@28216|Betaproteobacteria,4A9VN@80864|Comamonadaceae	28216|Betaproteobacteria	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_7682204_8	395495.Lcho_1097	1.229e-155	519.0	COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2VIMG@28216|Betaproteobacteria,1KJXF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
PYH2_k127_7682204_19	391735.Veis_2127	1.258e-07	59.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2VMJ5@28216|Betaproteobacteria,4ABP8@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PYH2_k127_7682204_14	614083.AWQR01000002_gene2987	7.229e-66	231.0	COG0590@1|root,COG0590@2|Bacteria,1RCXB@1224|Proteobacteria,2VQ7B@28216|Betaproteobacteria,4ADWG@80864|Comamonadaceae	28216|Betaproteobacteria	FJ	Cmp dcmp deaminase zinc-binding	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
PYH2_k127_7682204_7	243365.CV_0752	1.704e-172	559.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,2KRIN@206351|Neisseriales	206351|Neisseriales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
PYH2_k127_7682204_17	1123261.AXDW01000002_gene1684	6.425e-35	138.0	COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria,1SE8Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7682204_6	243365.CV_0750	4.868e-173	556.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,2KRGW@206351|Neisseriales	206351|Neisseriales	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
PYH2_k127_7682204_10	243365.CV_0749	8.957e-142	475.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,2KRG3@206351|Neisseriales	206351|Neisseriales	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
PYH2_k127_7682204_13	1123261.AXDW01000002_gene1687	2.009e-83	293.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,1S9RQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Formyl transferase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_C,Formyl_trans_N
PYH2_k127_7693083_4	420662.Mpe_A3116	1.297e-125	405.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,1KJUP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
PYH2_k127_7693083_0	1265502.KB905948_gene991	1.927e-177	560.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2W19X@28216|Betaproteobacteria,4ABCC@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH2_k127_7693083_1	864051.BurJ1DRAFT_1140	6.089e-176	555.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria,1KKHF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH2_k127_7693083_3	987059.RBXJA2T_01120	3.176e-162	516.0	COG1173@1|root,COG1173@2|Bacteria,1MUG0@1224|Proteobacteria,2VIN2@28216|Betaproteobacteria,1KJH2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	N-terminal TM domain of oligopeptide transport permease C	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PYH2_k127_7693083_2	1265502.KB905948_gene996	5.355e-165	524.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VHEF@28216|Betaproteobacteria,4ABQ2@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_7701369_1	1157708.KB907453_gene4278	2.441e-38	149.0	2BZ0R@1|root,2Z7U0@2|Bacteria,1MX37@1224|Proteobacteria,2VN75@28216|Betaproteobacteria,4AH58@80864|Comamonadaceae	28216|Betaproteobacteria	E	Nitrile hydratase, alpha chain	nthA	-	4.2.1.84	ko:K01721	ko00364,ko00380,ko00627,ko00643,ko01120,map00364,map00380,map00627,map00643,map01120	-	R02828,R04020,R05379,R05596,R07780,R07854	RC00483,RC00792,RC01345,RC01432	ko00000,ko00001,ko01000	-	-	-	NHase_alpha
PYH2_k127_7701369_0	1232437.KL661978_gene3781	5.933e-58	213.0	COG0457@1|root,COG3712@1|root,COG0457@2|Bacteria,COG3712@2|Bacteria,1RJUD@1224|Proteobacteria,42P27@68525|delta/epsilon subdivisions,2WK9Y@28221|Deltaproteobacteria,2MJZE@213118|Desulfobacterales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_8,TonB_dep_Rec,zinc_ribbon_4
PYH2_k127_7713237_0	864051.BurJ1DRAFT_0835	5.559e-172	550.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,2VTTR@28216|Betaproteobacteria,1KIVH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Tryptophan halogenase	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
PYH2_k127_7713237_2	864051.BurJ1DRAFT_0244	2.517e-45	174.0	2CD1X@1|root,345HP@2|Bacteria,1P1WD@1224|Proteobacteria,2W4MV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7713237_1	402626.Rpic_1236	6.917e-109	355.0	COG2225@1|root,COG2225@2|Bacteria,1MVEV@1224|Proteobacteria,2VJK0@28216|Betaproteobacteria,1K4T4@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Belongs to the malate synthase family	aceB	-	2.3.3.9	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	M00012	R00472	RC00004,RC00308,RC02747	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_synthase
PYH2_k127_7721380_3	261292.Nit79A3_2068	2.34e-25	106.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,2VW5A@28216|Betaproteobacteria,373PD@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
PYH2_k127_7721380_1	172088.AUGA01000048_gene907	5.513e-67	237.0	COG4278@1|root,COG4278@2|Bacteria,1RBTS@1224|Proteobacteria,2U33M@28211|Alphaproteobacteria,3JWV5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	phenylacetate-CoA ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7721380_0	1265503.KB905169_gene332	2.926e-81	299.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,1RMFJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH2_k127_7721380_4	420662.Mpe_A1593	0.0001658	50.0	COG2010@1|root,COG2010@2|Bacteria,1N4RA@1224|Proteobacteria,2VVFA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
PYH2_k127_7721380_2	1094980.Mpsy_0015	1.954e-50	187.0	COG2133@1|root,COG3794@1|root,arCOG10180@1|root,arCOG02796@2157|Archaea,arCOG02929@2157|Archaea,arCOG10180@2157|Archaea,2XT1Q@28890|Euryarchaeota,2NADP@224756|Methanomicrobia	224756|Methanomicrobia	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
PYH2_k127_7734264_3	1182590.BN5_00542	5.241e-12	76.0	COG2199@1|root,COG2199@2|Bacteria,1QTT5@1224|Proteobacteria,1T1G8@1236|Gammaproteobacteria,1YDQJ@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	T	7TM diverse intracellular signalling	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,GGDEF
PYH2_k127_7734264_2	296591.Bpro_4840	8.732e-20	93.0	2E7T6@1|root,3328B@2|Bacteria,1N8UT@1224|Proteobacteria,2VVWC@28216|Betaproteobacteria,4AG0G@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7734264_0	1123487.KB892845_gene359	7.967e-103	337.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria,2KVEQ@206389|Rhodocyclales	206389|Rhodocyclales	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
PYH2_k127_7738724_0	1265502.KB905929_gene2316	1.231e-292	905.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,4AAU8@80864|Comamonadaceae	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PYH2_k127_7738724_1	1286631.X805_04320	2.503e-86	291.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,1KJ9J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
PYH2_k127_7743175_17	1071679.BG57_32990	1.487e-27	113.0	COG3415@1|root,COG3415@2|Bacteria,1NB90@1224|Proteobacteria,2W6FF@28216|Betaproteobacteria,1KAC9@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Winged helix-turn helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_29,HTH_33
PYH2_k127_7743175_5	983917.RGE_34140	6.033e-112	368.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,2VKF3@28216|Betaproteobacteria,1KK8S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator, Crp Fnr family	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
PYH2_k127_7743175_3	1265502.KB905933_gene2025	1.261e-182	574.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,4A9J5@80864|Comamonadaceae	28216|Betaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PYH2_k127_7743175_15	420662.Mpe_A1117	1.538e-39	149.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,1KMD7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
PYH2_k127_7743175_18	580332.Slit_0699	1.821e-24	102.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,44W27@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
PYH2_k127_7743175_1	1265502.KB905933_gene2022	7.282e-202	643.0	COG1398@1|root,COG1398@2|Bacteria,1N2MA@1224|Proteobacteria,2VHRS@28216|Betaproteobacteria,4AB2U@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM fatty acid desaturase	-	-	1.14.19.1	ko:K00507	ko01040,ko01212,ko03320,ko04152,ko04212,map01040,map01212,map03320,map04152,map04212	-	R02222	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	DDE_Tnp_ISL3,FA_desaturase
PYH2_k127_7743175_2	1265502.KB905933_gene2021	4.755e-184	595.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,4A9KC@80864|Comamonadaceae	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
PYH2_k127_7743175_7	1265502.KB905933_gene2020	1.311e-90	304.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,4AC47@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
PYH2_k127_7743175_0	395495.Lcho_0739	3.583e-209	659.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,1KISX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
PYH2_k127_7743175_9	864051.BurJ1DRAFT_3715	1.674e-68	236.0	COG2030@1|root,COG2030@2|Bacteria,1RIBV@1224|Proteobacteria,2VTGX@28216|Betaproteobacteria,1KKWK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
PYH2_k127_7743175_13	1504672.669784883	4.302e-46	174.0	COG0671@1|root,COG0671@2|Bacteria,1R6RS@1224|Proteobacteria,2WFTD@28216|Betaproteobacteria,4AI0A@80864|Comamonadaceae	28216|Betaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
PYH2_k127_7743175_6	420662.Mpe_A0054	1.133e-102	343.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,1KKS0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
PYH2_k127_7743175_4	296591.Bpro_2738	4.147e-157	502.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2WC2E@28216|Betaproteobacteria,4AIRV@80864|Comamonadaceae	28216|Betaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	-	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
PYH2_k127_7743175_8	1454004.AW11_01869	1.85e-71	248.0	COG4094@1|root,COG4094@2|Bacteria,1RDHB@1224|Proteobacteria,2VQBI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NnrUfamily protein	nnrU	-	-	-	-	-	-	-	-	-	-	-	NnrU
PYH2_k127_7743175_12	272560.BPSL3088	5.293e-51	186.0	COG5608@1|root,COG5608@2|Bacteria,1N15F@1224|Proteobacteria,2VUHP@28216|Betaproteobacteria,1K8Y1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Water Stress and Hypersensitive response	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
PYH2_k127_7743175_10	216591.BCAS0746	3.046e-56	207.0	COG0317@1|root,COG0317@2|Bacteria,1RGUA@1224|Proteobacteria,2VQUA@28216|Betaproteobacteria,1K6XY@119060|Burkholderiaceae	28216|Betaproteobacteria	KT	SMART metal-dependent phosphohydrolase, HD region	-	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	HD_4
PYH2_k127_7743175_14	1128421.JAGA01000001_gene2006	1.621e-45	169.0	COG2363@1|root,COG2363@2|Bacteria,2NRMS@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF423)	ywdK	-	-	-	-	-	-	-	-	-	-	-	DUF423
PYH2_k127_7743175_11	296591.Bpro_2637	3.049e-52	193.0	COG5579@1|root,COG5579@2|Bacteria,1RGXV@1224|Proteobacteria,2VV4U@28216|Betaproteobacteria,4AF66@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1810
PYH2_k127_7743175_16	595494.Tola_0686	5.554e-30	122.0	COG2327@1|root,COG2327@2|Bacteria,1R84F@1224|Proteobacteria,1SG0C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
PYH2_k127_7753714_3	767817.Desgi_3962	1.657e-15	79.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,263JY@186807|Peptococcaceae	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH2_k127_7753714_2	502025.Hoch_4147	7.114e-52	188.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1MUEA@1224|Proteobacteria,42MER@68525|delta/epsilon subdivisions,2WIYV@28221|Deltaproteobacteria,2YW7P@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
PYH2_k127_7753714_1	987059.RBXJA2T_08660	2.941e-72	251.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VQBC@28216|Betaproteobacteria,1KNPC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Class II Aldolase and Adducin N-terminal domain	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
PYH2_k127_7753714_0	987059.RBXJA2T_08665	9.453e-119	387.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2VI2X@28216|Betaproteobacteria,1KNB2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
PYH2_k127_77550_11	338969.Rfer_4079	6.92e-10	67.0	COG3303@1|root,COG3303@2|Bacteria,1NT38@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_77550_3	864051.BurJ1DRAFT_0795	6.182e-106	349.0	COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria,2VQPA@28216|Betaproteobacteria,1KN88@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
PYH2_k127_77550_0	522306.CAP2UW1_0926	3.7e-322	993.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VKSM@28216|Betaproteobacteria,1KR8N@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Fumarate reductase flavoprotein C-term	frdA	-	1.3.5.4	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PYH2_k127_77550_2	522306.CAP2UW1_0925	1.056e-127	414.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VNVE@28216|Betaproteobacteria,1KR8I@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	frdB	-	1.3.5.4	ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
PYH2_k127_77550_7	748247.AZKH_0531	2.025e-44	176.0	COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,2VTQJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Fumarate reductase subunit C	frdC	-	-	ko:K00246	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_C
PYH2_k127_77550_5	1454004.AW11_01462	9.574e-52	193.0	COG3080@1|root,COG3080@2|Bacteria,1RDZD@1224|Proteobacteria,2VTX9@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane	frdD	-	-	ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00150,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Fumarate_red_D
PYH2_k127_77550_4	580332.Slit_1215	2.178e-57	203.0	28PZA@1|root,2ZCIS@2|Bacteria,1RCMD@1224|Proteobacteria,2VYEF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_77550_6	1123401.JHYQ01000030_gene3083	2.656e-49	179.0	COG1569@1|root,COG1569@2|Bacteria,1N1T4@1224|Proteobacteria,1S7J5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxin-antitoxin system, toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
PYH2_k127_77550_8	1140.Synpcc7942_0541	5.309e-24	102.0	2C16Q@1|root,330H3@2|Bacteria,1G90Z@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HicB,RHH_1
PYH2_k127_77550_10	1504672.669784323	3.935e-20	95.0	2DS4B@1|root,33EG1@2|Bacteria,1NJ4Q@1224|Proteobacteria,2VYF7@28216|Betaproteobacteria,4AFXF@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_77550_1	1265502.KB905946_gene1152	1.47e-263	822.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,4AAXQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
PYH2_k127_7768897_0	748247.AZKH_p0136	5.053e-166	529.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VQCJ@28216|Betaproteobacteria,2KY98@206389|Rhodocyclales	206389|Rhodocyclales	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
PYH2_k127_7768897_1	76114.ebA3133	1.586e-98	324.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VRU7@28216|Betaproteobacteria,2KY85@206389|Rhodocyclales	206389|Rhodocyclales	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	-	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
PYH2_k127_7768897_2	1198449.ACAM_1322	0.0004358	48.0	COG1339@1|root,arCOG01904@2157|Archaea,2XR2X@28889|Crenarchaeota	28889|Crenarchaeota	H	Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN)	ribK	-	2.7.1.161	ko:K07732	ko00740,ko01100,map00740,map01100	-	R08574	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CTP-dep_RFKase,HTH_24,MarR_2
PYH2_k127_7771952_2	1265502.KB905937_gene2595	1.465e-99	330.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VJ8W@28216|Betaproteobacteria,4ACID@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	dmlR2	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_7771952_3	1538295.JY96_12885	2.968e-55	197.0	COG3556@1|root,COG3556@2|Bacteria,1PSJ4@1224|Proteobacteria,2WA8W@28216|Betaproteobacteria,1KP5Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2214)	-	-	-	ko:K08983	-	-	-	-	ko00000	-	-	-	DUF2214
PYH2_k127_7771952_5	1304883.KI912532_gene887	7.164e-18	89.0	2EGQC@1|root,33AGI@2|Bacteria,1NGA3@1224|Proteobacteria,2VY93@28216|Betaproteobacteria,2KZKF@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
PYH2_k127_7771952_1	1538295.JY96_12895	1.437e-210	667.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,1KJ5A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
PYH2_k127_7771952_0	420662.Mpe_A0153	1.156e-281	873.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,1KJQ9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Arginyl-tRNA synthetase	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
PYH2_k127_7771952_4	420662.Mpe_A0152	1.056e-25	109.0	COG3087@1|root,COG3087@2|Bacteria,1RI6A@1224|Proteobacteria,2VR10@28216|Betaproteobacteria,1KKS6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Sporulation related domain	ftsN	-	-	-	-	-	-	-	-	-	-	-	SPOR
PYH2_k127_7775050_0	864051.BurJ1DRAFT_2518	1.266e-239	747.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,1KIW5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PYH2_k127_7775050_1	1286631.X805_02570	4.962e-107	364.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,1KKX1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaC	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
PYH2_k127_7775050_2	864051.BurJ1DRAFT_2519	4.412e-53	204.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,1KK38@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
PYH2_k127_7783780_1	1218084.BBJK01000086_gene5764	2.523e-177	560.0	COG1804@1|root,COG1804@2|Bacteria,1MU5U@1224|Proteobacteria,2VJB6@28216|Betaproteobacteria,1K1NA@119060|Burkholderiaceae	28216|Betaproteobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH2_k127_7783780_5	543728.Vapar_5729	5.449e-124	403.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,2VJSY@28216|Betaproteobacteria,4AC5T@80864|Comamonadaceae	28216|Betaproteobacteria	P	Membrane protein TerC	terC	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,TerC
PYH2_k127_7783780_2	1504672.669784495	5.598e-149	476.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VIZP@28216|Betaproteobacteria,4A9RC@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_7783780_0	543913.D521_0884	0.0	1024.0	COG3960@1|root,COG3960@2|Bacteria,1MV88@1224|Proteobacteria,2VHT9@28216|Betaproteobacteria,1KR7A@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	gcl	-	4.1.1.47	ko:K01608	ko00630,ko01100,map00630,map01100	-	R00013	RC00899	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PYH2_k127_7783780_4	296591.Bpro_4562	4.448e-126	436.0	COG3622@1|root,COG3622@2|Bacteria,1MV53@1224|Proteobacteria,2VJ19@28216|Betaproteobacteria,4ACR0@80864|Comamonadaceae	28216|Betaproteobacteria	G	Belongs to the hyi family	hyi	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
PYH2_k127_7783780_3	296591.Bpro_3102	9.252e-137	444.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,2VIVI@28216|Betaproteobacteria,4AAME@80864|Comamonadaceae	28216|Betaproteobacteria	I	6-phosphogluconate dehydrogenase, NAD-binding	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
PYH2_k127_7791081_1	1207063.P24_00620	1.305e-93	315.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,2TTGM@28211|Alphaproteobacteria,2JPI4@204441|Rhodospirillales	204441|Rhodospirillales	E	Peptidase family M20/M25/M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_7791081_2	887062.HGR_13124	3.769e-45	167.0	COG2329@1|root,COG2329@2|Bacteria,1N078@1224|Proteobacteria,2VSX8@28216|Betaproteobacteria,4AER0@80864|Comamonadaceae	28216|Betaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
PYH2_k127_7791081_5	1123355.JHYO01000014_gene1048	2.757e-38	148.0	COG1959@1|root,COG1959@2|Bacteria,1PZ79@1224|Proteobacteria,2UCUA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
PYH2_k127_7791081_3	1150469.RSPPHO_01831	1.04e-43	165.0	COG0454@1|root,COG0456@2|Bacteria,1N43K@1224|Proteobacteria,2UDB6@28211|Alphaproteobacteria,2JTG2@204441|Rhodospirillales	204441|Rhodospirillales	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PYH2_k127_7791081_4	1380394.JADL01000002_gene1592	1.151e-43	163.0	COG5496@1|root,COG5496@2|Bacteria,1RKFT@1224|Proteobacteria,2U5DE@28211|Alphaproteobacteria,2JUEU@204441|Rhodospirillales	204441|Rhodospirillales	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7791081_0	85643.Tmz1t_2959	0.0	1279.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VMWP@28216|Betaproteobacteria,2KVYZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.5.1,3.1.2.25	ko:K18361	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001,ko01000	-	-	-	Molybdopterin,Molydop_binding
PYH2_k127_7803824_3	1265502.KB905932_gene1907	3.115e-99	330.0	COG0265@1|root,COG0265@2|Bacteria,1QWA4@1224|Proteobacteria,2VK6X@28216|Betaproteobacteria,4A9X2@80864|Comamonadaceae	28216|Betaproteobacteria	O	peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
PYH2_k127_7803824_0	1504672.669783784	2.655e-166	537.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AD31@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
PYH2_k127_7803824_2	365046.Rta_32000	4.98e-123	404.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,2VJHU@28216|Betaproteobacteria,4A9S6@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
PYH2_k127_7803824_1	864051.BurJ1DRAFT_3538	7.242e-144	465.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,1KKCR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
PYH2_k127_7803824_4	106370.Francci3_2192	1.32e-26	112.0	COG1669@1|root,COG1669@2|Bacteria,2IQTT@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
PYH2_k127_7803824_6	42256.RradSPS_1874	7.593e-21	96.0	COG2361@1|root,COG2361@2|Bacteria,2INJK@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
PYH2_k127_7803824_5	1286631.X805_14520	1.657e-23	100.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,1KJKV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Ammonium Transporter	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
PYH2_k127_7808074_0	983917.RGE_16760	1.198e-169	537.0	COG1868@1|root,COG1868@2|Bacteria,1MX01@1224|Proteobacteria,2VI0A@28216|Betaproteobacteria,1KK5A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar motor switch	fliM	-	-	ko:K02416	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliM,FliMN_C
PYH2_k127_7808074_1	864051.BurJ1DRAFT_0264	7.68e-49	180.0	COG1580@1|root,COG1580@2|Bacteria,1RARK@1224|Proteobacteria,2VTGH@28216|Betaproteobacteria,1KKTE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Controls the rotational direction of flagella during chemotaxis	fliL	-	-	ko:K02415	-	-	-	-	ko00000,ko02035	-	-	-	FliL
PYH2_k127_7813248_2	864051.BurJ1DRAFT_0218	2.656e-05	46.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,2VMMY@28216|Betaproteobacteria,1KKHK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	frk	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PYH2_k127_7813248_1	420662.Mpe_A0244	4.68e-112	370.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,1KJD9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
PYH2_k127_7813248_0	864051.BurJ1DRAFT_4621	2.14e-276	871.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,1KJV8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
PYH2_k127_7815675_2	395495.Lcho_0043	1.098e-62	235.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1QVGV@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PYH2_k127_7815675_4	1380390.JIAT01000010_gene4968	1.878e-34	138.0	COG3631@1|root,COG3631@2|Bacteria,2GRE5@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
PYH2_k127_7815675_1	748247.AZKH_p0192	7.499e-188	592.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2VI6J@28216|Betaproteobacteria,2KVJH@206389|Rhodocyclales	28216|Betaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_7815675_6	264198.Reut_A0536	2.867e-17	91.0	2DP14@1|root,3303I@2|Bacteria,1N7JW@1224|Proteobacteria,2VW7N@28216|Betaproteobacteria,1KANT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7815675_5	1304883.KI912532_gene508	2.195e-27	120.0	2CESE@1|root,32S0D@2|Bacteria,1RHTD@1224|Proteobacteria,2VSJ5@28216|Betaproteobacteria,2KWQC@206389|Rhodocyclales	206389|Rhodocyclales	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA,Gly-zipper_YMGG
PYH2_k127_7815675_0	1288494.EBAPG3_4550	0.0	1245.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,371RW@32003|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
PYH2_k127_7815675_7	1163409.UUA_09091	4.491e-12	70.0	2EHXM@1|root,33BP4@2|Bacteria,1NGZB@1224|Proteobacteria,1STAC@1236|Gammaproteobacteria,1X8Z6@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF3606)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3606
PYH2_k127_7815675_3	498211.CJA_3229	6.673e-35	139.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,1SF5B@1236|Gammaproteobacteria,1FH89@10|Cellvibrio	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
PYH2_k127_7825005_3	887062.HGR_00951	3.625e-07	52.0	COG2371@1|root,COG2371@2|Bacteria,1MZQZ@1224|Proteobacteria,2VMRF@28216|Betaproteobacteria,4A9Z2@80864|Comamonadaceae	28216|Betaproteobacteria	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
PYH2_k127_7825005_2	1286631.X805_11270	1.591e-89	302.0	COG0830@1|root,COG0830@2|Bacteria,1MW8Q@1224|Proteobacteria,2VRF6@28216|Betaproteobacteria,1KIX3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
PYH2_k127_7825005_1	395495.Lcho_0585	3.736e-118	390.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VH2U@28216|Betaproteobacteria,1KJRE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KO	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG	ureG	-	-	ko:K03189	-	-	-	-	ko00000	-	-	-	cobW
PYH2_k127_7825005_0	983917.RGE_40870	1.932e-140	451.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,1KKE2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	OU	peptidase S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
PYH2_k127_7825216_2	987059.RBXJA2T_16507	9.816e-41	152.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,1KK6W@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
PYH2_k127_7825216_1	1265502.KB905934_gene3183	6.154e-155	494.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,4AAQ0@80864|Comamonadaceae	28216|Betaproteobacteria	E	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
PYH2_k127_7825216_0	1265502.KB905934_gene3182	3.614e-198	621.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,4AABX@80864|Comamonadaceae	28216|Betaproteobacteria	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
PYH2_k127_7841448_6	941449.dsx2_0625	3.911e-06	50.0	COG1319@1|root,COG1319@2|Bacteria,1RCRH@1224|Proteobacteria,42TSE@68525|delta/epsilon subdivisions,2WQWM@28221|Deltaproteobacteria,2MB7C@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	CO dehydrogenase flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
PYH2_k127_7841448_5	76114.ebA2063	2.001e-77	262.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ75@28216|Betaproteobacteria,2KW1Q@206389|Rhodocyclales	28216|Betaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3,1.3.7.9	ko:K03518,ko:K04107	ko00362,ko00627,ko01100,ko01120,ko01220,map00362,map00627,map01100,map01120,map01220	-	R05316,R11168	RC00490,RC02800	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_7841448_1	76114.ebA2064	0.0	1373.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2VIR8@28216|Betaproteobacteria,2KYPD@206389|Rhodocyclales	206389|Rhodocyclales	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH2_k127_7841448_2	76114.ebA2066	7.371e-206	646.0	COG1804@1|root,COG1804@2|Bacteria,1MU2K@1224|Proteobacteria,2VHFW@28216|Betaproteobacteria,2KXPJ@206389|Rhodocyclales	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH2_k127_7841448_3	1244869.H261_14140	4.694e-122	397.0	COG1028@1|root,COG1028@2|Bacteria,1MXFZ@1224|Proteobacteria,2TQZ9@28211|Alphaproteobacteria,2JRAG@204441|Rhodospirillales	204441|Rhodospirillales	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_7841448_0	748247.AZKH_3649	0.0	1437.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,2KY8I@206389|Rhodocyclales	206389|Rhodocyclales	C	COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
PYH2_k127_7841448_4	76114.ebA2079	2.971e-82	282.0	COG3213@1|root,COG3213@2|Bacteria,1MUJK@1224|Proteobacteria,2VJ75@28216|Betaproteobacteria,2KU72@206389|Rhodocyclales	206389|Rhodocyclales	P	protein involved in response to NO	-	-	-	ko:K07234	-	-	-	-	ko00000	-	-	-	NnrS
PYH2_k127_7843287_1	987059.RBXJA2T_07328	1.552e-38	156.0	2D1A4@1|root,32XQB@2|Bacteria,1N5B0@1224|Proteobacteria,2VV8M@28216|Betaproteobacteria,1KNXU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
PYH2_k127_7843287_0	946483.Cenrod_1459	1.746e-150	482.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2VJUV@28216|Betaproteobacteria,4AC86@80864|Comamonadaceae	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
PYH2_k127_7856535_1	614083.AWQR01000007_gene420	3.598e-50	183.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,2VHF0@28216|Betaproteobacteria,4AAN1@80864|Comamonadaceae	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_7856535_3	522306.CAP2UW1_2179	5.848e-16	82.0	COG1544@1|root,COG1544@2|Bacteria,1N8CQ@1224|Proteobacteria,2VVX7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
PYH2_k127_7856535_0	420662.Mpe_A1726	7.236e-82	281.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,1KKRG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the BI1 family	yccA	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
PYH2_k127_7856535_2	1159870.KB907784_gene2498	8.932e-17	83.0	COG1595@1|root,COG1595@2|Bacteria,1N00E@1224|Proteobacteria,2VQNP@28216|Betaproteobacteria,3T4G8@506|Alcaligenaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
PYH2_k127_7861651_5	62928.azo2599	5.088e-45	168.0	COG0662@1|root,COG0662@2|Bacteria,1N40H@1224|Proteobacteria,2VWGU@28216|Betaproteobacteria,2KZHA@206389|Rhodocyclales	206389|Rhodocyclales	G	Auxin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7861651_2	1538295.JY96_09285	8.322e-112	376.0	COG0583@1|root,COG0583@2|Bacteria,1MV06@1224|Proteobacteria,2VHGD@28216|Betaproteobacteria,1KM0G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K18900	-	M00698	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_7861651_6	365044.Pnap_2414	2.471e-33	138.0	2CDK0@1|root,32YHE@2|Bacteria,1NAHY@1224|Proteobacteria,2VWGS@28216|Betaproteobacteria,4AFT5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7861651_7	543728.Vapar_2352	6.807e-33	128.0	2EFGB@1|root,33990@2|Bacteria,1N7I5@1224|Proteobacteria,2VWTQ@28216|Betaproteobacteria,4AEZU@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7861651_1	1163617.SCD_n01992	1.648e-180	574.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
PYH2_k127_7861651_3	977880.RALTA_B1327	4.146e-96	327.0	COG3181@1|root,COG3181@2|Bacteria,1N00G@1224|Proteobacteria,2VN46@28216|Betaproteobacteria,1KCCT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_7861651_0	1216976.AX27061_4363	6.648e-253	788.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,2VQVS@28216|Betaproteobacteria,3T1F9@506|Alcaligenaceae	28216|Betaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
PYH2_k127_7861651_8	864051.BurJ1DRAFT_3757	9.102e-11	75.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,2VI8X@28216|Betaproteobacteria,1KJC3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	helicase superfamily c-terminal domain	lhr	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
PYH2_k127_7861651_4	864051.BurJ1DRAFT_3764	1.574e-51	188.0	COG1525@1|root,COG1525@2|Bacteria,1PQ4N@1224|Proteobacteria,2W9KT@28216|Betaproteobacteria,1KMJ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Staphylococcal nuclease homologue	-	-	-	-	-	-	-	-	-	-	-	-	SNase
PYH2_k127_7882299_0	358220.C380_03070	0.0	1064.0	COG3320@1|root,COG4221@1|root,COG3320@2|Bacteria,COG4221@2|Bacteria,1QSHC@1224|Proteobacteria,2VKRX@28216|Betaproteobacteria,4AB29@80864|Comamonadaceae	28216|Betaproteobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4,adh_short
PYH2_k127_7882299_3	595537.Varpa_2954	3.864e-37	148.0	2DXN5@1|root,345NS@2|Bacteria,1P1QC@1224|Proteobacteria,2W488@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7882299_1	296591.Bpro_0189	1.027e-79	271.0	COG3791@1|root,COG3791@2|Bacteria,1RFBP@1224|Proteobacteria,2VQN8@28216|Betaproteobacteria,4AE1T@80864|Comamonadaceae	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GFA
PYH2_k127_7882299_4	1255043.TVNIR_1335	5.275e-19	91.0	COG1872@1|root,COG1872@2|Bacteria	2|Bacteria	I	DUF167	CP_0257	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
PYH2_k127_7882299_5	987059.RBXJA2T_06870	1.105e-17	84.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2VHDA@28216|Betaproteobacteria,1KPAR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
PYH2_k127_7904636_1	365044.Pnap_1105	1.944e-274	860.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,4AB99@80864|Comamonadaceae	28216|Betaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
PYH2_k127_7904636_0	543728.Vapar_0415	3.504e-301	939.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria,4ACF1@80864|Comamonadaceae	28216|Betaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48,Glyco_hydro_77
PYH2_k127_7904678_4	420662.Mpe_A2512	1.104e-30	126.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2VN4R@28216|Betaproteobacteria,1KKG6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	LysE type translocator	-	-	-	ko:K05834	-	-	-	-	ko00000,ko02000	2.A.76.1.1	-	-	LysE
PYH2_k127_7904678_0	420662.Mpe_A3556	3.964e-241	750.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,1KIWT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
PYH2_k127_7904678_6	395495.Lcho_3716	1.842e-23	101.0	COG3339@1|root,COG3339@2|Bacteria,1NHKG@1224|Proteobacteria,2VX0A@28216|Betaproteobacteria,1KPHB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
PYH2_k127_7904678_3	1265502.KB905955_gene459	2.654e-38	149.0	2ASHY@1|root,31HYC@2|Bacteria,1RIM4@1224|Proteobacteria,2VSD6@28216|Betaproteobacteria,4AEK4@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7904678_1	864051.BurJ1DRAFT_0196	1.39e-180	567.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,1KJXS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
PYH2_k127_7904678_5	1286631.X805_40780	5.952e-28	113.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2VVV6@28216|Betaproteobacteria,1KMKD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
PYH2_k127_7904678_2	1286631.X805_40790	1.534e-68	241.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,1KKPX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02841,ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
PYH2_k127_7921383_0	1000565.METUNv1_00490	2.543e-173	557.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,2KU93@206389|Rhodocyclales	206389|Rhodocyclales	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
PYH2_k127_7952766_4	1123504.JQKD01000005_gene4750	4.273e-25	109.0	COG1082@1|root,COG1082@2|Bacteria,1R87Z@1224|Proteobacteria,2VQ98@28216|Betaproteobacteria,4AITZ@80864|Comamonadaceae	28216|Betaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
PYH2_k127_7952766_2	1192868.CAIU01000016_gene2098	2.935e-98	344.0	COG1116@1|root,COG1116@2|Bacteria,1MUIM@1224|Proteobacteria,2TRHM@28211|Alphaproteobacteria,43JUU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component	MA20_28765	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PYH2_k127_7952766_0	1205680.CAKO01000007_gene4346	1.806e-153	493.0	COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2TSHF@28211|Alphaproteobacteria,2JQCD@204441|Rhodospirillales	204441|Rhodospirillales	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
PYH2_k127_7952766_1	1205680.CAKO01000007_gene4347	2.876e-104	354.0	COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2TSAS@28211|Alphaproteobacteria	1224|Proteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	MA20_28785	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PYH2_k127_7952766_3	1137271.AZUM01000003_gene3754	3.569e-51	187.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4E68P@85010|Pseudonocardiales	201174|Actinobacteria	M	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain	-	-	5.5.1.1	ko:K01856	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R05300,R05390,R06989,R08116,R09229	RC00903,RC01038,RC01108,RC01321,RC01356	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
PYH2_k127_7968138_2	1027273.GZ77_21095	3.17e-10	64.0	2EMCZ@1|root,33F1W@2|Bacteria,1QTAY@1224|Proteobacteria,1SUNK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Excisionase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_7968138_3	296591.Bpro_5541	3.035e-09	63.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
PYH2_k127_7968138_1	1504672.669784423	7.439e-51	185.0	COG3436@1|root,COG3436@2|Bacteria,1RHJ1@1224|Proteobacteria,2VTHQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM IS66 Orf2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	TnpB_IS66
PYH2_k127_7968138_0	1504672.669786924	4.956e-218	689.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,2VKSJ@28216|Betaproteobacteria,4ACTJ@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
PYH2_k127_796838_2	420662.Mpe_A1439	3.28e-99	329.0	COG3596@1|root,COG3596@2|Bacteria,1R01T@1224|Proteobacteria,2WHSI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF3482)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3482,MMR_HSR1
PYH2_k127_796838_3	1380387.JADM01000020_gene3728	1.093e-66	244.0	COG1960@1|root,COG1960@2|Bacteria,1N2Q3@1224|Proteobacteria,1SHNN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_M
PYH2_k127_796838_4	365044.Pnap_1306	7.281e-30	128.0	2D78S@1|root,32TNJ@2|Bacteria,1N0VB@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4864)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4864
PYH2_k127_796838_1	420662.Mpe_A1436	6.704e-117	385.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,1KJZ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	enoyl-CoA hydratase	fadB3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_796838_0	420662.Mpe_A1435	6.803e-315	970.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,2VIJ8@28216|Betaproteobacteria,1KJ4H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_797810_0	525904.Tter_1321	5.278e-104	346.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
PYH2_k127_797810_1	365046.Rta_19980	5.561e-89	298.0	COG3239@1|root,COG3239@2|Bacteria,1MUHK@1224|Proteobacteria,2VSCY@28216|Betaproteobacteria,4AEWX@80864|Comamonadaceae	28216|Betaproteobacteria	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
PYH2_k127_8009686_14	1265502.KB905929_gene2301	4e-66	243.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,4AACE@80864|Comamonadaceae	28216|Betaproteobacteria	O	protein-L-isoaspartate O-methyltransferase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
PYH2_k127_8009686_9	864051.BurJ1DRAFT_2444	1.021e-122	398.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,1KJMJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
PYH2_k127_8009686_7	1265502.KB905929_gene2299	2.613e-162	520.0	COG0604@1|root,COG0604@2|Bacteria,1MWRK@1224|Proteobacteria,2VJ1C@28216|Betaproteobacteria,4A9W7@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_8009686_11	864051.BurJ1DRAFT_2442	2.852e-109	358.0	COG2197@1|root,COG2197@2|Bacteria,1Q7GF@1224|Proteobacteria,2VN5C@28216|Betaproteobacteria,1KKI8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
PYH2_k127_8009686_1	420662.Mpe_A1248	8.608e-238	757.0	COG4585@1|root,COG4585@2|Bacteria,1R8DN@1224|Proteobacteria,2VPJ9@28216|Betaproteobacteria,1KKHD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
PYH2_k127_8009686_15	395495.Lcho_3748	1.642e-45	177.0	COG0640@1|root,COG0640@2|Bacteria,1Q9DY@1224|Proteobacteria,2VVWF@28216|Betaproteobacteria,1KMER@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
PYH2_k127_8009686_10	266264.Rmet_1517	1.731e-112	382.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,1K4K1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
PYH2_k127_8009686_2	1265502.KB905959_gene258	8.873e-212	665.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,4AB3S@80864|Comamonadaceae	28216|Betaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
PYH2_k127_8009686_4	1538295.JY96_14505	3.494e-192	602.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,1KKA5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
PYH2_k127_8009686_12	266264.Rmet_1514	7.909e-92	308.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,1KDR9@119060|Burkholderiaceae	28216|Betaproteobacteria	G	haloacid dehalogenase-like hydrolase	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PYH2_k127_8009686_0	266264.Rmet_1513	0.0	1059.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,1KCWD@119060|Burkholderiaceae	28216|Betaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
PYH2_k127_8009686_6	395495.Lcho_3754	1.958e-176	561.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,1KIVW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Phosphoribulokinase	cbbP	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
PYH2_k127_8009686_3	987059.RBXJA2T_18688	6.458e-207	647.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,1KKER@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp1	-	3.1.3.11,3.1.3.37	ko:K01086,ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R01845,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
PYH2_k127_8009686_8	983917.RGE_36030	3.215e-158	504.0	COG0464@1|root,COG0464@2|Bacteria,1MUCN@1224|Proteobacteria,2VIA8@28216|Betaproteobacteria,1KJSZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	cbbX	-	-	-	-	-	-	-	-	-	-	-	AAA
PYH2_k127_8009686_13	983917.RGE_36050	7.786e-77	261.0	COG4451@1|root,COG4451@2|Bacteria,1R9ZE@1224|Proteobacteria,2VQKV@28216|Betaproteobacteria,1KKJ2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Ribulose bisphosphate carboxylase, small chain	cbbS	-	4.1.1.39	ko:K01602	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_small
PYH2_k127_8009686_5	987059.RBXJA2T_18708	9.311e-187	584.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria,1KJRD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbL	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
PYH2_k127_8014261_0	1265502.KB905931_gene1662	1.209e-146	479.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,4AB41@80864|Comamonadaceae	28216|Betaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
PYH2_k127_8014261_3	358220.C380_07910	4.796e-60	218.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,4AB7W@80864|Comamonadaceae	28216|Betaproteobacteria	S	transferase hexapeptide	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
PYH2_k127_8014261_2	983917.RGE_14930	3.081e-104	345.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2VIX0@28216|Betaproteobacteria,1KK4N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
PYH2_k127_8014261_1	864051.BurJ1DRAFT_0597	6.5e-125	406.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,2VQG9@28216|Betaproteobacteria,1KMAN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_8016711_0	864051.BurJ1DRAFT_3702	7.768e-248	768.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,1KJSQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
PYH2_k127_8016711_3	864051.BurJ1DRAFT_3695	4.472e-110	363.0	COG2267@1|root,COG2267@2|Bacteria,1RFE1@1224|Proteobacteria,2VHIU@28216|Betaproteobacteria,1KJWK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
PYH2_k127_8016711_6	1454004.AW11_00806	9.093e-23	112.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
PYH2_k127_8016711_4	864051.BurJ1DRAFT_3660	3.38e-92	318.0	COG0861@1|root,COG0861@2|Bacteria,1QZU6@1224|Proteobacteria,2VJDD@28216|Betaproteobacteria,1KPIP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	membrane protein, terc	-	-	-	-	-	-	-	-	-	-	-	-	TerC
PYH2_k127_8016711_2	1117943.SFHH103_04113	6.058e-126	426.0	COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,TPR_8
PYH2_k127_8016711_5	1038859.AXAU01000005_gene5142	1.118e-32	133.0	COG3350@1|root,COG3350@2|Bacteria,1N0GC@1224|Proteobacteria,2UBRM@28211|Alphaproteobacteria,3JXT6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YHS domain protein	-	-	-	-	-	-	-	-	-	-	-	-	YHS
PYH2_k127_8016711_1	864051.BurJ1DRAFT_3694	1.093e-142	457.0	COG3484@1|root,COG3484@2|Bacteria,1N057@1224|Proteobacteria,2VHD7@28216|Betaproteobacteria,1KKEW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	-	ko:K07395	-	-	-	-	ko00000	-	-	-	Proteasome
PYH2_k127_8016711_7	1265502.KB905931_gene1671	3.677e-08	55.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,4A9P0@80864|Comamonadaceae	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
PYH2_k127_8033482_4	1265502.KB905933_gene1982	6.151e-85	289.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,4ABGB@80864|Comamonadaceae	28216|Betaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
PYH2_k127_8033482_6	935567.JAES01000028_gene2671	3.202e-45	179.0	COG0251@1|root,COG0251@2|Bacteria,1MZ5K@1224|Proteobacteria,1S5WM@1236|Gammaproteobacteria,1X6UX@135614|Xanthomonadales	135614|Xanthomonadales	J	translation initiation inhibitor, yjgF family	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
PYH2_k127_8033482_3	420662.Mpe_A2757	1.639e-111	362.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,1KKES@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the SUA5 family	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
PYH2_k127_8033482_1	420662.Mpe_A2756	7.717e-139	447.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,1KJWE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	phosphoesterase, PHP	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
PYH2_k127_8033482_0	76114.ebA6077	6.783e-147	474.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria,2KV9P@206389|Rhodocyclales	206389|Rhodocyclales	G	COG2133 Glucose sorbosone dehydrogenases	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
PYH2_k127_8033482_2	426114.THI_2279	2.175e-132	438.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria,1KK4Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Glucose sorbosone	yliI	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
PYH2_k127_8033482_5	395495.Lcho_4315	2.094e-61	213.0	COG2133@1|root,COG2133@2|Bacteria,1MV2E@1224|Proteobacteria,2VH6H@28216|Betaproteobacteria,1KK4Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Glucose sorbosone	yliI	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	GSDH
PYH2_k127_8049264_4	864051.BurJ1DRAFT_1686	4.729e-98	324.0	COG0410@1|root,COG0410@2|Bacteria,1R5HF@1224|Proteobacteria,2VS8X@28216|Betaproteobacteria	28216|Betaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_8049264_3	864051.BurJ1DRAFT_1687	6.974e-103	367.0	COG0411@1|root,COG0411@2|Bacteria,1R5MA@1224|Proteobacteria,2VQBK@28216|Betaproteobacteria	28216|Betaproteobacteria	E	abc transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_8049264_2	864051.BurJ1DRAFT_1688	4.267e-144	463.0	COG4177@1|root,COG4177@2|Bacteria,1QF6I@1224|Proteobacteria,2VRRP@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PYH2_k127_8049264_1	864051.BurJ1DRAFT_1689	4.148e-157	499.0	COG0559@1|root,COG0559@2|Bacteria,1MYEW@1224|Proteobacteria,2VKZN@28216|Betaproteobacteria	28216|Betaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_8049264_0	864051.BurJ1DRAFT_1690	1.23e-251	781.0	COG0683@1|root,COG0683@2|Bacteria,1MWNB@1224|Proteobacteria,2VKVZ@28216|Betaproteobacteria	28216|Betaproteobacteria	E	abc-type branched-chain amino acid transport	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_8049264_5	864051.BurJ1DRAFT_3900	2.95e-82	278.0	COG2186@1|root,COG2186@2|Bacteria,1MY1K@1224|Proteobacteria,2VP3Y@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PYH2_k127_8052690_1	420662.Mpe_A0338	5.341e-142	452.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VIMM@28216|Betaproteobacteria,1KK63@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	fdwB	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
PYH2_k127_8052690_0	864051.BurJ1DRAFT_1510	0.0	1067.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,2VP2Q@28216|Betaproteobacteria,1KJAE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Formate dehydrogenase, alpha subunit	fdhA1	-	1.17.1.9,1.17.99.7	ko:K00123,ko:K22015	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
PYH2_k127_8076918_3	59538.XP_005979423.1	1.438e-06	50.0	COG0277@1|root,KOG1231@2759|Eukaryota,38FXH@33154|Opisthokonta,3BEEV@33208|Metazoa,3CRTP@33213|Bilateria,4801S@7711|Chordata,492UT@7742|Vertebrata,3JDRF@40674|Mammalia,4J43Y@91561|Cetartiodactyla	33208|Metazoa	C	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
PYH2_k127_8076918_2	987059.RBXJA2T_08765	4.773e-49	179.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,1KM47@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	regulatory protein, MerR	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
PYH2_k127_8076918_1	420662.Mpe_A1882	4.807e-58	203.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,1KM26@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PYH2_k127_8076918_0	395495.Lcho_1750	0.0	1029.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,1KJ89@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
PYH2_k127_8078764_0	748247.AZKH_1501	3.062e-272	849.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,2KVAY@206389|Rhodocyclales	28216|Betaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
PYH2_k127_8090392_1	420662.Mpe_A0800	3.628e-133	433.0	COG0583@1|root,COG0583@2|Bacteria,1N663@1224|Proteobacteria,2VJ6D@28216|Betaproteobacteria,1KJXD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PYH2_k127_8090392_0	1123504.JQKD01000013_gene1057	1.315e-209	662.0	COG4630@1|root,COG4630@2|Bacteria,1MWI1@1224|Proteobacteria,2VI0J@28216|Betaproteobacteria,4AAFW@80864|Comamonadaceae	28216|Betaproteobacteria	C	CO dehydrogenase flavoprotein domain protein	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
PYH2_k127_8090392_2	595537.Varpa_4513	1.027e-49	180.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,4AB6W@80864|Comamonadaceae	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH2_k127_8107446_2	240015.ACP_0367	1.433e-17	85.0	COG2755@1|root,COG5301@1|root,COG2755@2|Bacteria,COG5301@2|Bacteria,3Y82Q@57723|Acidobacteria,2JN5M@204432|Acidobacteriia	204432|Acidobacteriia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8107446_1	557598.LHK_01273	4.249e-42	173.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
PYH2_k127_8107446_0	983917.RGE_24230	1.62e-262	812.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,1KIX7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
PYH2_k127_8117637_5	1123392.AQWL01000004_gene2720	2.338e-151	494.0	COG2067@1|root,COG2067@2|Bacteria,1MV7W@1224|Proteobacteria,2VKWX@28216|Betaproteobacteria,1KT8K@119069|Hydrogenophilales	119069|Hydrogenophilales	I	Outer membrane protein transport protein (OMPP1/FadL/TodX)	-	-	-	-	-	-	-	-	-	-	-	-	Toluene_X
PYH2_k127_8117637_9	864051.BurJ1DRAFT_3307	3.95e-107	349.0	COG0599@1|root,COG2146@1|root,COG0599@2|Bacteria,COG2146@2|Bacteria,1RCCG@1224|Proteobacteria	1224|Proteobacteria	P	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Rieske
PYH2_k127_8117637_2	1123392.AQWL01000001_gene1443	2.242e-230	737.0	COG0659@1|root,COG0659@2|Bacteria,1MWDF@1224|Proteobacteria,2VHKJ@28216|Betaproteobacteria,1KSX1@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
PYH2_k127_8117637_7	1123368.AUIS01000031_gene1418	1.997e-138	448.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,1T8C8@1236|Gammaproteobacteria,2NCKI@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PYH2_k127_8117637_14	1123368.AUIS01000031_gene1419	3.783e-16	82.0	2EGXE@1|root,329EB@2|Bacteria,1NIPX@1224|Proteobacteria,1SHV3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8117637_8	1163617.SCD_n01211	4.559e-135	438.0	COG3302@1|root,COG3302@2|Bacteria,1MWY1@1224|Proteobacteria,2VN4W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K21309	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	DmsC
PYH2_k127_8117637_6	580332.Slit_1710	1.913e-140	463.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44W9R@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	ko:K21308	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4
PYH2_k127_8117637_0	580332.Slit_1711	0.0	1735.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44WAX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.8.5.6	ko:K21307	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R11487	RC00168	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
PYH2_k127_8117637_12	545264.KB898754_gene1831	7.332e-63	222.0	COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,1S2YE@1236|Gammaproteobacteria,1WY1W@135613|Chromatiales	135613|Chromatiales	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
PYH2_k127_8117637_3	1163617.SCD_n01884	1.057e-194	616.0	COG1148@1|root,COG1148@2|Bacteria,1Q0ZF@1224|Proteobacteria,2VUBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Glucose inhibited division protein A	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388,ko:K16885	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored
PYH2_k127_8117637_1	1163617.SCD_n01883	0.0	1080.0	COG1148@1|root,COG1908@1|root,COG1148@2|Bacteria,COG1908@2|Bacteria,1MWAG@1224|Proteobacteria,2WEVG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	ko:K16886	-	-	-	-	ko00000	-	-	-	Fer4,FlpD,Pyr_redox_2
PYH2_k127_8117637_10	1163617.SCD_n01882	1.165e-97	323.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
PYH2_k127_8117637_4	1123392.AQWL01000008_gene1153	1.5e-153	490.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
PYH2_k127_8117637_11	1454004.AW11_00293	2.926e-89	302.0	COG1024@1|root,COG1024@2|Bacteria,1MUJ7@1224|Proteobacteria,2VIP5@28216|Betaproteobacteria,1KQB6@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	fadB3	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_8117637_13	1095769.CAHF01000005_gene1585	1.224e-51	188.0	COG4257@1|root,COG4257@2|Bacteria,1QR8W@1224|Proteobacteria,2VX5D@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid	vgb	-	-	ko:K18235	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	-
PYH2_k127_8117752_4	1458427.BAWN01000007_gene494	4.45e-20	93.0	COG0411@1|root,COG0411@2|Bacteria,1MVAU@1224|Proteobacteria,2VP5B@28216|Betaproteobacteria,4AAZV@80864|Comamonadaceae	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_8117752_3	887062.HGR_05324	2.327e-145	468.0	COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,2VNRM@28216|Betaproteobacteria,4AAJ7@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_8117752_2	614083.AWQR01000007_gene375	5.492e-147	471.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2VHAJ@28216|Betaproteobacteria,4AB5H@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_8117752_1	1100720.ALKN01000040_gene2167	1.199e-210	664.0	COG0683@1|root,COG0683@2|Bacteria,1NHBN@1224|Proteobacteria,2VPWN@28216|Betaproteobacteria,4AC19@80864|Comamonadaceae	28216|Betaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_8117752_0	365046.Rta_16200	2.545e-249	781.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIJX@28216|Betaproteobacteria,4AA7T@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	matB	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_8117752_5	296591.Bpro_2093	8.24e-11	64.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,2VICM@28216|Betaproteobacteria,4ACFI@80864|Comamonadaceae	28216|Betaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_8125633_4	864051.BurJ1DRAFT_1672	1.131e-102	347.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,2VRTK@28216|Betaproteobacteria,1KIZN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	D	Belongs to the ParA family	fleN	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,ParA
PYH2_k127_8125633_5	864051.BurJ1DRAFT_1671	1.916e-90	310.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VKPP@28216|Betaproteobacteria,1KIUE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PYH2_k127_8125633_0	420662.Mpe_A2703	6.232e-183	579.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,1KKAT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
PYH2_k127_8125633_6	987059.RBXJA2T_18553	7.013e-82	285.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,1KKJK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
PYH2_k127_8125633_3	420662.Mpe_A2705	6.43e-116	377.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,1KJ3P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
PYH2_k127_8125633_1	864051.BurJ1DRAFT_1664	3.611e-169	534.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,1KIYH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	phosphatase	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
PYH2_k127_8125633_2	420662.Mpe_A2707	4.299e-166	524.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,2VHMW@28216|Betaproteobacteria,1KJQ3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	KLT	Serine threonine protein kinase	spkD	-	-	-	-	-	-	-	-	-	-	-	Pkinase
PYH2_k127_8126414_2	614083.AWQR01000055_gene1969	7.082e-32	130.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,4A9MA@80864|Comamonadaceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
PYH2_k127_8126414_1	614083.AWQR01000055_gene1970	1.029e-93	322.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Pfam ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PYH2_k127_8126414_0	614083.AWQR01000055_gene1971	2.731e-178	566.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,4AJVP@80864|Comamonadaceae	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PYH2_k127_8127569_4	1286631.X805_33570	5.928e-119	383.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHET@28216|Betaproteobacteria,1KJ16@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_8127569_7	1265502.KB905934_gene3301	6.78e-22	98.0	2EBRC@1|root,33J4P@2|Bacteria,1NNUS@1224|Proteobacteria,2VYRX@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8127569_1	1286631.X805_33560	1.18e-208	656.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2VHRJ@28216|Betaproteobacteria,1KKCG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	AMP-binding enzyme	paaK_2	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
PYH2_k127_8127569_2	395495.Lcho_3442	1.738e-177	559.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,2VHVS@28216|Betaproteobacteria,1KJ67@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	tctC4	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_8127569_6	983917.RGE_07650	4.391e-56	201.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,2VR31@28216|Betaproteobacteria,1KM0A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
PYH2_k127_8127569_3	864051.BurJ1DRAFT_1073	2.449e-153	488.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,1KK7U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
PYH2_k127_8127569_0	420662.Mpe_A3150	2.978e-215	674.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,1KK1I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
PYH2_k127_8127569_5	983917.RGE_07620	1.831e-92	312.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,1KIVP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
PYH2_k127_8138216_0	1123392.AQWL01000008_gene1153	1.14e-145	476.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,2VV9S@28216|Betaproteobacteria,1KSCV@119069|Hydrogenophilales	119069|Hydrogenophilales	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
PYH2_k127_8138216_1	1123393.KB891317_gene2470	6.951e-90	299.0	COG1150@1|root,COG1150@2|Bacteria,1RHH3@1224|Proteobacteria,2W0PC@28216|Betaproteobacteria,1KSVN@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S dicluster domain	-	-	-	ko:K16887	-	-	-	-	ko00000	-	-	-	Fer4_17
PYH2_k127_8235637_4	1499967.BAYZ01000046_gene2637	3.251e-12	68.0	COG0444@1|root,COG0444@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	dppD	-	-	ko:K02031,ko:K02032,ko:K12371	ko02010,ko02024,map02010,map02024	M00239,M00324	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PYH2_k127_8235637_1	1293054.HSACCH_00337	2.017e-99	331.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WAI0@53433|Halanaerobiales	186801|Clostridia	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain	appF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PYH2_k127_8235637_0	864051.BurJ1DRAFT_0140	7.049e-254	790.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2VKA4@28216|Betaproteobacteria,1KMX8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	ABC-type dipeptide transport system, periplasmic component	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH2_k127_8235637_3	543728.Vapar_0482	4.136e-59	209.0	COG3631@1|root,COG3631@2|Bacteria,1RDED@1224|Proteobacteria,2VS1C@28216|Betaproteobacteria,4AE6M@80864|Comamonadaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
PYH2_k127_8235637_2	1156919.QWC_21589	3.252e-74	254.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2VKAQ@28216|Betaproteobacteria,3T3RA@506|Alcaligenaceae	28216|Betaproteobacteria	J	COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases	-	-	3.5.1.4,6.3.5.6,6.3.5.7	ko:K01426,ko:K02433	ko00330,ko00360,ko00380,ko00627,ko00643,ko00970,ko01100,ko01120,map00330,map00360,map00380,map00627,map00643,map00970,map01100,map01120	-	R02540,R03096,R03180,R03905,R03909,R04212,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PYH2_k127_8253530_2	420662.Mpe_A0332	2.521e-08	56.0	2E54A@1|root,32ZX9@2|Bacteria,1N8HJ@1224|Proteobacteria,2VVW9@28216|Betaproteobacteria,1KMNY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1840)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1840
PYH2_k127_8253530_0	1265502.KB905948_gene980	1.462e-104	343.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VJ4C@28216|Betaproteobacteria,4ADIA@80864|Comamonadaceae	28216|Betaproteobacteria	S	Phosphatidylethanolamine-binding protein	bbsI	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
PYH2_k127_8253530_1	420662.Mpe_A0330	5.033e-80	271.0	COG0406@1|root,COG0406@2|Bacteria,1NPC4@1224|Proteobacteria,2VQTE@28216|Betaproteobacteria,1KKM9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	phosphoglycerate mutase	gpmB	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
PYH2_k127_8290736_5	864051.BurJ1DRAFT_3854	1.17e-51	189.0	COG2271@1|root,COG2271@2|Bacteria,1QVKZ@1224|Proteobacteria,2WHHX@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_8290736_6	296591.Bpro_1595	1.645e-48	197.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VS6Z@28216|Betaproteobacteria,4ADJG@80864|Comamonadaceae	28216|Betaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	gag-asp_proteas
PYH2_k127_8290736_3	1265502.KB905964_gene1386	5.878e-64	228.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,4ADFY@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
PYH2_k127_8290736_1	987059.RBXJA2T_16722	2.144e-179	572.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2VI7I@28216|Betaproteobacteria,1KJJE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
PYH2_k127_8290736_0	864051.BurJ1DRAFT_2065	1.628e-257	798.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,1KJ2B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 2 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
PYH2_k127_8290736_2	296591.Bpro_1464	5.989e-96	323.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria,2VJKU@28216|Betaproteobacteria,4AB6Q@80864|Comamonadaceae	28216|Betaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
PYH2_k127_8290736_4	864051.BurJ1DRAFT_3847	8.846e-52	210.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VIA6@28216|Betaproteobacteria,1KKA9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
PYH2_k127_8304135_1	243365.CV_0745	2.815e-116	381.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,2VKEP@28216|Betaproteobacteria,2KRMF@206351|Neisseriales	206351|Neisseriales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
PYH2_k127_8304135_0	243365.CV_0747	2.876e-171	548.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2VJV2@28216|Betaproteobacteria,2KSJ3@206351|Neisseriales	206351|Neisseriales	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
PYH2_k127_8304135_2	1120999.JONM01000005_gene3783	4.361e-09	60.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,2VKAI@28216|Betaproteobacteria,2KSMS@206351|Neisseriales	206351|Neisseriales	J	Formyl transferase, C-terminal domain	-	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
PYH2_k127_8320510_1	172088.AUGA01000014_gene3003	6.589e-160	513.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TUKZ@28211|Alphaproteobacteria,3JST2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Belongs to the amidase family	MA20_08725	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
PYH2_k127_8320510_2	313606.M23134_08425	5.649e-51	192.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,4P2KW@976|Bacteroidetes	976|Bacteroidetes	M	Glycosyltransferase family 17	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_17
PYH2_k127_8320510_0	666685.R2APBS1_3701	2.499e-171	542.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,1RNJD@1236|Gammaproteobacteria,1X3HX@135614|Xanthomonadales	135614|Xanthomonadales	GM	dehydratase	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
PYH2_k127_8327918_0	765914.ThisiDRAFT_1164	2.867e-86	292.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,1RMGJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related proteins	-	-	1.3.99.23	ko:K09516	ko00830,map00830	-	R07163	RC01835	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase,FAD_binding_6,NAD_binding_1,NAD_binding_8
PYH2_k127_8327918_1	543728.Vapar_2831	2.911e-81	279.0	COG1376@1|root,COG1376@2|Bacteria,1RAMJ@1224|Proteobacteria,2VQ9N@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8330896_0	56780.SYN_01931	1.155e-145	472.0	COG2885@1|root,COG2982@1|root,COG2885@2|Bacteria,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria,2MQYM@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
PYH2_k127_8330896_6	1163617.SCD_n01516	5.77e-33	146.0	COG3218@1|root,COG3218@2|Bacteria,1NCG2@1224|Proteobacteria,2VWSK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
PYH2_k127_8330896_4	614083.AWQR01000025_gene3665	1.812e-54	219.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,4AAHD@80864|Comamonadaceae	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
PYH2_k127_8330896_2	1163617.SCD_n01514	6.028e-113	369.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Abc transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
PYH2_k127_8330896_1	1163617.SCD_n01513	7.685e-120	405.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
PYH2_k127_8330896_7	748280.NH8B_0787	2.488e-18	96.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,2VWZD@28216|Betaproteobacteria	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
PYH2_k127_8330896_8	748280.NH8B_0787	2.63e-09	61.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,2VWZD@28216|Betaproteobacteria	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
PYH2_k127_8330896_5	1458275.AZ34_10875	1.733e-45	169.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,2VUGY@28216|Betaproteobacteria,4AJHU@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
PYH2_k127_8330896_3	338969.Rfer_2330	1.404e-74	252.0	COG2050@1|root,COG2050@2|Bacteria,1N57X@1224|Proteobacteria,2VTJB@28216|Betaproteobacteria,4AHYH@80864|Comamonadaceae	28216|Betaproteobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
PYH2_k127_8358965_3	983917.RGE_26110	7.236e-52	187.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,1KJWV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
PYH2_k127_8358965_0	420662.Mpe_A1864	8.081e-123	406.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,2VQK6@28216|Betaproteobacteria,1KJ3H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
PYH2_k127_8358965_1	1265502.KB905940_gene2983	7.827e-120	401.0	COG0824@1|root,COG2153@1|root,COG0824@2|Bacteria,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,4A9NN@80864|Comamonadaceae	28216|Betaproteobacteria	S	Thioesterase superfamily protein	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
PYH2_k127_8358965_2	215803.DB30_0841	1.904e-102	366.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,438M3@68525|delta/epsilon subdivisions,2X1ZS@28221|Deltaproteobacteria,2YX8A@29|Myxococcales	28221|Deltaproteobacteria	T	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,Guanylate_cyc,TPR_12
PYH2_k127_8390068_2	269799.Gmet_2150	4.821e-75	273.0	COG1024@1|root,COG1024@2|Bacteria,1R8QP@1224|Proteobacteria,42S3Y@68525|delta/epsilon subdivisions,2WNXJ@28221|Deltaproteobacteria,43UFV@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	bamR	-	4.2.1.100	ko:K07537	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05597	RC03168	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH2_k127_8390068_0	1187851.A33M_3194	2.818e-178	572.0	COG1024@1|root,COG1024@2|Bacteria,1QY95@1224|Proteobacteria,2U4PY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	3.7.1.21	ko:K07539	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05593,R05594,R10696	RC01430,RC01431,RC03237	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
PYH2_k127_8390068_1	1121918.ARWE01000001_gene3595	2.413e-159	510.0	COG1064@1|root,COG1064@2|Bacteria,1QVIH@1224|Proteobacteria,42NMX@68525|delta/epsilon subdivisions,2WJGB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	bamQ	-	1.1.1.368	ko:K07538	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R05581	RC00850	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_8390068_3	1123355.JHYO01000001_gene3226	9.333e-14	74.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,2TU21@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N,Transketolase_C
PYH2_k127_8392187_3	983917.RGE_16800	2.162e-28	126.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2VHQ5@28216|Betaproteobacteria,1KIVI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
PYH2_k127_8392187_2	983917.RGE_16810	1.264e-54	200.0	COG1317@1|root,COG1317@2|Bacteria,1NMQE@1224|Proteobacteria,2VSQ0@28216|Betaproteobacteria,1KKT2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar assembly protein FliH	fliH	-	-	ko:K02411	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	FliH
PYH2_k127_8392187_0	983917.RGE_16820	1.248e-163	520.0	COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,2VI19@28216|Betaproteobacteria,1KK1Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	flagellar motor switch protein	fliG	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
PYH2_k127_8392187_1	864051.BurJ1DRAFT_0258	8.738e-78	266.0	COG1766@1|root,COG1766@2|Bacteria,1MUQR@1224|Proteobacteria,2VI9M@28216|Betaproteobacteria,1KJ2E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	The M ring may be actively involved in energy transduction	fliF	-	-	ko:K02409	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	YscJ_FliF,YscJ_FliF_C
PYH2_k127_8422122_7	930169.B5T_00826	1.667e-09	58.0	COG1012@1|root,COG2030@1|root,COG1012@2|Bacteria,COG2030@2|Bacteria,1MWD4@1224|Proteobacteria,1RVX0@1236|Gammaproteobacteria,1XISM@135619|Oceanospirillales	135619|Oceanospirillales	CI	Aldehyde dehydrogenase	-	-	1.2.1.91,3.3.2.12	ko:K02618	ko00360,ko01120,map00360,map01120	-	R09820,R09836	RC00080,RC02667	ko00000,ko00001,ko01000	-	-	-	Aldedh,MaoC_dehydratas
PYH2_k127_8422122_3	864051.BurJ1DRAFT_4391	1.71e-52	186.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,1KM4M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
PYH2_k127_8422122_0	365046.Rta_35150	1.34e-301	930.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,4A9QT@80864|Comamonadaceae	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
PYH2_k127_8422122_2	378806.STAUR_6017	2.041e-93	329.0	COG0520@1|root,COG0520@2|Bacteria,1QU0N@1224|Proteobacteria,42YS3@68525|delta/epsilon subdivisions,2WU59@28221|Deltaproteobacteria,2YTT1@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
PYH2_k127_8422122_5	1223521.BBJX01000002_gene2857	3.975e-26	126.0	COG1612@1|root,COG1612@2|Bacteria,1NDQQ@1224|Proteobacteria,2VWPV@28216|Betaproteobacteria,4AGYI@80864|Comamonadaceae	28216|Betaproteobacteria	O	Cytochrome oxidase assembly protein	-	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
PYH2_k127_8422122_1	1223521.BBJX01000002_gene2865	3.132e-163	529.0	COG0843@1|root,COG0843@2|Bacteria,1QJ23@1224|Proteobacteria,2VKFW@28216|Betaproteobacteria,4AH9U@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome C and Quinol oxidase polypeptide I	-	-	-	-	-	-	-	-	-	-	-	-	COX1
PYH2_k127_8422122_4	1437824.BN940_02361	9.489e-39	150.0	2CB7M@1|root,31H4T@2|Bacteria,1MYWT@1224|Proteobacteria,2VSTJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8422122_6	1223521.BBJX01000002_gene2863	7.621e-22	99.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2VNFS@28216|Betaproteobacteria,4AH2R@80864|Comamonadaceae	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,Fer4_7,FlpD
PYH2_k127_8447480_1	864051.BurJ1DRAFT_0521	0.0	1012.0	COG1960@1|root,COG1960@2|Bacteria,1MU20@1224|Proteobacteria,2VIJU@28216|Betaproteobacteria,1KJ7P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
PYH2_k127_8447480_4	420662.Mpe_A0418	4.34e-62	216.0	COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,2VS9I@28216|Betaproteobacteria,1KM82@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
PYH2_k127_8447480_0	1265502.KB905945_gene648	0.0	1281.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VHS7@28216|Betaproteobacteria,4AAU6@80864|Comamonadaceae	28216|Betaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	fadB	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
PYH2_k127_8447480_2	420662.Mpe_A0416	7.093e-207	648.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,1KJKX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_8447480_3	987059.RBXJA2T_15688	1.593e-112	372.0	COG1024@1|root,COG1024@2|Bacteria,1Q67Q@1224|Proteobacteria,2VJC1@28216|Betaproteobacteria,1KITU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
PYH2_k127_8447480_5	388051.AUFE01000012_gene2816	3.011e-59	208.0	COG1764@1|root,COG1764@2|Bacteria,1RI5C@1224|Proteobacteria,2WFNG@28216|Betaproteobacteria,1KI45@119060|Burkholderiaceae	28216|Betaproteobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
PYH2_k127_8447480_6	983917.RGE_09190	9.698e-55	197.0	COG2755@1|root,COG2755@2|Bacteria,1RE1B@1224|Proteobacteria,2VUB8@28216|Betaproteobacteria,1KMNC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PYH2_k127_8453463_3	522306.CAP2UW1_1327	2.115e-112	374.0	COG1145@1|root,COG1290@1|root,COG1908@1|root,COG1145@2|Bacteria,COG1290@2|Bacteria,COG1908@2|Bacteria,1QSPU@1224|Proteobacteria,2VNFS@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,Fer4_7,FlpD
PYH2_k127_8453463_7	522306.CAP2UW1_1788	2.366e-60	221.0	COG1999@1|root,COG1999@2|Bacteria,1N6WC@1224|Proteobacteria,2VMIP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
PYH2_k127_8453463_6	1223521.BBJX01000002_gene2861	9.583e-75	276.0	COG0109@1|root,COG0109@2|Bacteria,1MW3S@1224|Proteobacteria,2VM89@28216|Betaproteobacteria,4AHA1@80864|Comamonadaceae	28216|Betaproteobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
PYH2_k127_8453463_0	1223521.BBJX01000002_gene2860	8.621e-256	799.0	COG0843@1|root,COG0843@2|Bacteria,1R57U@1224|Proteobacteria,2VJ1N@28216|Betaproteobacteria,4AHFT@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM Cytochrome c oxidase, subunit I	cbaA	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
PYH2_k127_8453463_5	1437824.BN940_02346	7.141e-89	295.0	COG1622@1|root,COG1622@2|Bacteria,1NZNI@1224|Proteobacteria,2VNRT@28216|Betaproteobacteria	28216|Betaproteobacteria	C	cytochrome c oxidase (Subunit II)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
PYH2_k127_8453463_8	1123360.thalar_02883	1.128e-12	70.0	2ERCE@1|root,33IY3@2|Bacteria,1NNN9@1224|Proteobacteria,2UXY5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8453463_1	522306.CAP2UW1_1324	1.926e-225	715.0	COG0543@1|root,COG1018@1|root,COG1290@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,COG1290@2|Bacteria,1MV72@1224|Proteobacteria,2VI6M@28216|Betaproteobacteria,1KR75@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b(N-terminal)/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_B,FAD_binding_6,Fer2,NAD_binding_1
PYH2_k127_8453463_4	395495.Lcho_1454	1.944e-103	348.0	COG0664@1|root,COG0664@2|Bacteria,1R5P7@1224|Proteobacteria,2VIQI@28216|Betaproteobacteria,1KKH6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	dnrD	-	-	ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PYH2_k127_8453463_2	864051.BurJ1DRAFT_1541	5.144e-155	494.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VHQF@28216|Betaproteobacteria,1KK8H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Trypsin	-	-	1.3.1.74	ko:K08070	-	-	-	-	ko00000,ko01000	-	-	-	PDZ_2,Trypsin_2
PYH2_k127_8461180_11	395495.Lcho_1989	1.823e-27	112.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,2VMN7@28216|Betaproteobacteria,1KKDP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.215,1.1.1.79,1.1.1.81	ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R01739	RC00031,RC00042,RC00084	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH2_k127_8461180_2	864051.BurJ1DRAFT_2220	0.0	1040.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,2VHB9@28216|Betaproteobacteria,1KJ3Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH2_k127_8461180_8	395495.Lcho_1987	8.078e-78	263.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VQ9M@28216|Betaproteobacteria,1KKYN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	2Fe-2S -binding domain	iorA	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PYH2_k127_8461180_4	420662.Mpe_A1514	3.247e-210	663.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,1KK8Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
PYH2_k127_8461180_6	420662.Mpe_A1515	4.541e-133	435.0	COG0477@1|root,COG2814@2|Bacteria,1R3WC@1224|Proteobacteria,2VKT9@28216|Betaproteobacteria,1KKFE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_8461180_9	1265502.KB905931_gene1723	7.54e-47	175.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria,4ADKN@80864|Comamonadaceae	28216|Betaproteobacteria	O	PFAM Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
PYH2_k127_8461180_3	1265502.KB905931_gene1724	5e-323	1000.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,4AAI1@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
PYH2_k127_8461180_5	358220.C380_11395	1.144e-142	458.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,4AAPJ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
PYH2_k127_8461180_7	864051.BurJ1DRAFT_2227	3.583e-115	386.0	COG4566@1|root,COG4566@2|Bacteria,1N6WR@1224|Proteobacteria,2VM61@28216|Betaproteobacteria,1KIT8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Regulator	fixJ	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K13041	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
PYH2_k127_8461180_1	420662.Mpe_A2129	0.0	1158.0	COG3290@1|root,COG4191@1|root,COG3290@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria,1KK93@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	fixL	-	2.7.13.3	ko:K11711	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9
PYH2_k127_8461180_0	983917.RGE_23650	0.0	1613.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,1KK2I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
PYH2_k127_8461180_10	883126.HMPREF9710_01761	5.692e-35	135.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,2VIHA@28216|Betaproteobacteria,4733P@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceF	-	1.8.1.4,2.3.1.12	ko:K00382,ko:K00627	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R02569,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834,RC02857	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH2_k127_8468880_0	640081.Dsui_0605	3.176e-198	622.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,2KU9J@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
PYH2_k127_8468880_1	76114.ebA1770	1.11e-74	252.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,2KVBG@206389|Rhodocyclales	206389|Rhodocyclales	NU	twitching motility protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
PYH2_k127_8532975_3	395495.Lcho_3496	1.303e-27	115.0	COG3017@1|root,COG3017@2|Bacteria,1N2F2@1224|Proteobacteria,2VUJH@28216|Betaproteobacteria,1KM9Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
PYH2_k127_8532975_0	987059.RBXJA2T_15543	2.942e-199	636.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,1KJG2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
PYH2_k127_8532975_2	864051.BurJ1DRAFT_4447	6.983e-114	374.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,1KJ6R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
PYH2_k127_8532975_1	420662.Mpe_A3234	6.072e-186	591.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,2VKA1@28216|Betaproteobacteria,1KJS4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
PYH2_k127_8536412_0	987059.RBXJA2T_03364	8.324e-170	540.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,1KJDJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
PYH2_k127_8536412_1	983917.RGE_26910	1.026e-86	306.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,1KJBS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
PYH2_k127_8536412_3	316055.RPE_1625	1.658e-31	141.0	COG0346@1|root,COG0346@2|Bacteria,1MZRH@1224|Proteobacteria,2UD6G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH2_k127_8536412_2	1123504.JQKD01000032_gene4479	8.19e-70	241.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,4ADJH@80864|Comamonadaceae	28216|Betaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
PYH2_k127_8540939_3	338969.Rfer_0385	4.998e-11	64.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,2VN6N@28216|Betaproteobacteria,4AEZ2@80864|Comamonadaceae	28216|Betaproteobacteria	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
PYH2_k127_8540939_2	1429046.RR21198_2000	1.332e-19	93.0	COG0236@1|root,COG0236@2|Bacteria,2GR2W@201174|Actinobacteria,4G799@85025|Nocardiaceae	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
PYH2_k127_8540939_0	189753.AXAS01000041_gene2530	7.134e-66	230.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2UEAM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NT	Single cache domain 3	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2
PYH2_k127_8540939_1	266264.Rmet_5588	1.046e-48	184.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,1K38N@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PYH2_k127_8562036_0	864051.BurJ1DRAFT_3973	1.483e-246	789.0	COG5434@1|root,COG5434@2|Bacteria,1R1VR@1224|Proteobacteria	1224|Proteobacteria	M	Heparinase II/III N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
PYH2_k127_8562036_1	864051.BurJ1DRAFT_3974	4.395e-148	475.0	COG0438@1|root,COG0438@2|Bacteria,1MVKK@1224|Proteobacteria,2VMU1@28216|Betaproteobacteria,1KMEA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	PFAM Glycosyl transferases group 1	epsN	-	2.4.1.348	ko:K12995	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
PYH2_k127_8569649_0	76114.ebA4202	4.788e-146	510.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2VJB8@28216|Betaproteobacteria,2KUFW@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
PYH2_k127_8569649_1	76114.ebA1189	2.278e-126	433.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2VHW1@28216|Betaproteobacteria,2KV5Q@206389|Rhodocyclales	206389|Rhodocyclales	M	surface antigen (D15)	-	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA
PYH2_k127_8569649_2	180281.CPCC7001_2088	2.1e-05	58.0	COG0385@1|root,COG0385@2|Bacteria,1GJMH@1117|Cyanobacteria,22TH4@167375|Cyanobium	1117|Cyanobacteria	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
PYH2_k127_8575400_3	1123368.AUIS01000028_gene1325	9.066e-68	236.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
PYH2_k127_8575400_2	323848.Nmul_A2158	5.026e-87	312.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,2VHYS@28216|Betaproteobacteria,373YE@32003|Nitrosomonadales	28216|Betaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
PYH2_k127_8575400_0	395495.Lcho_4020	4.748e-171	545.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,1KJF0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
PYH2_k127_8575400_1	296591.Bpro_1025	2.192e-122	396.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VJXE@28216|Betaproteobacteria,4AB6I@80864|Comamonadaceae	28216|Betaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
PYH2_k127_8577950_2	864051.BurJ1DRAFT_1337	2.627e-105	345.0	COG2321@1|root,COG2321@2|Bacteria,1MU4U@1224|Proteobacteria,2VH8U@28216|Betaproteobacteria,1KJJ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
PYH2_k127_8577950_0	388051.AUFE01000065_gene3879	9.469e-281	876.0	COG4670@1|root,COG4670@2|Bacteria,1MUJW@1224|Proteobacteria,2VH8B@28216|Betaproteobacteria,1K4Y9@119060|Burkholderiaceae	28216|Betaproteobacteria	I	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons	-	-	2.8.3.1	ko:K01026	ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120	-	R00928,R01449,R05508	RC00012,RC00014,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
PYH2_k127_8577950_3	196367.JNFG01000201_gene2810	5.301e-94	316.0	COG3897@1|root,COG3897@2|Bacteria,1MUWA@1224|Proteobacteria,2VQPT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Lysine methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_16,Methyltransf_23
PYH2_k127_8577950_1	257313.BP1980	1.547e-133	433.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VM2H@28216|Betaproteobacteria,3T57X@506|Alcaligenaceae	28216|Betaproteobacteria	L	Superfamily I DNA and RNA helicases	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PYH2_k127_8578901_0	76114.ebA6298	7.78e-126	434.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,2VIKY@28216|Betaproteobacteria,2KV0V@206389|Rhodocyclales	206389|Rhodocyclales	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
PYH2_k127_8578901_3	1342301.JASD01000003_gene5	1.511e-08	66.0	COG2931@1|root,COG5549@1|root,COG2931@2|Bacteria,COG5549@2|Bacteria,1NBPA@1224|Proteobacteria,2UI74@28211|Alphaproteobacteria	28211|Alphaproteobacteria	OQ	Domain of unknown function (DUF4214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,Peptidase_M10
PYH2_k127_8578901_2	983917.RGE_30180	1.716e-34	138.0	2DNV8@1|root,32ZAX@2|Bacteria,1R3MW@1224|Proteobacteria,2VWAR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
PYH2_k127_8578901_1	76114.ebA1984	1.751e-93	316.0	COG0625@1|root,COG0625@2|Bacteria,1N8XH@1224|Proteobacteria,2VIYW@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Glutathione S-transferase	gstP	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3
PYH2_k127_8588567_0	1288494.EBAPG3_5980	1.476e-137	462.0	COG3523@1|root,COG3523@2|Bacteria,1MV3D@1224|Proteobacteria,2VJ0M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	type VI secretion protein	icmF	-	-	ko:K11891	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	IcmF-related,IcmF_C,ImcF-related_N
PYH2_k127_8588567_2	765911.Thivi_2303	1.014e-36	152.0	COG3913@1|root,COG3913@2|Bacteria,1N01G@1224|Proteobacteria,1S6EQ@1236|Gammaproteobacteria,1WYTI@135613|Chromatiales	135613|Chromatiales	S	Uncharacterized protein conserved in bacteria (DUF2094)	-	-	-	ko:K11890	ko02025,map02025	-	-	-	ko00000,ko00001,ko02044	-	-	-	DUF2094
PYH2_k127_8588567_1	522306.CAP2UW1_2357	1.049e-68	253.0	COG4249@1|root,COG4249@2|Bacteria,1R3WZ@1224|Proteobacteria,2VSB5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
PYH2_k127_8591654_0	296591.Bpro_4696	2.838e-286	887.0	COG1178@1|root,COG1178@2|Bacteria,1MXZZ@1224|Proteobacteria,2VI17@28216|Betaproteobacteria,4ACCU@80864|Comamonadaceae	28216|Betaproteobacteria	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
PYH2_k127_8591654_1	296591.Bpro_4697	6.346e-16	79.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VKXZ@28216|Betaproteobacteria,4A9K4@80864|Comamonadaceae	28216|Betaproteobacteria	H	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily	phnW	-	2.6.1.37	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R04152	RC00008,RC00062	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5
PYH2_k127_8600091_4	1504672.669787493	1.405e-10	67.0	COG1716@1|root,COG3456@1|root,COG1716@2|Bacteria,COG3456@2|Bacteria,1R3R7@1224|Proteobacteria,2VPTI@28216|Betaproteobacteria,4AEAN@80864|Comamonadaceae	28216|Betaproteobacteria	T	FHA domain	-	-	-	ko:K07169,ko:K11913	ko02025,ko03070,map02025,map03070	-	-	-	ko00000,ko00001,ko02044	-	-	-	FHA
PYH2_k127_8600091_3	395495.Lcho_0402	1.308e-48	186.0	2BWWN@1|root,32XHS@2|Bacteria,1N289@1224|Proteobacteria,2VU35@28216|Betaproteobacteria,1KMCN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FecR
PYH2_k127_8600091_0	864051.BurJ1DRAFT_0167	5.907e-113	371.0	COG2770@1|root,COG2770@2|Bacteria,1QZYS@1224|Proteobacteria,2VJTC@28216|Betaproteobacteria,1KJFF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Protein of unknown function (DUF3365)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HAMP
PYH2_k127_8600091_1	1123504.JQKD01000002_gene3754	7.125e-104	354.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,4AD1S@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
PYH2_k127_8600091_2	1288494.EBAPG3_5990	4.276e-57	209.0	COG1360@1|root,COG3455@1|root,COG1360@2|Bacteria,COG3455@2|Bacteria,1MU13@1224|Proteobacteria,2VMB4@28216|Betaproteobacteria	28216|Betaproteobacteria	N	TIGRFAM type IV VI secretion system protein, DotU family	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DotU,OmpA
PYH2_k127_8616802_4	864051.BurJ1DRAFT_3942	8.102e-50	184.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,1KJ0A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	COG3170 Tfp pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
PYH2_k127_8616802_1	1223521.BBJX01000006_gene1743	2.109e-209	654.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,4AAJE@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
PYH2_k127_8616802_2	864051.BurJ1DRAFT_3944	3.078e-199	627.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,1KJSC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
PYH2_k127_8616802_3	864051.BurJ1DRAFT_3945	3.097e-127	408.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,1KK7A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
PYH2_k127_8616802_6	543728.Vapar_1424	1.222e-05	57.0	COG5510@1|root,COG5510@2|Bacteria	2|Bacteria	S	response to toxic substance	encAB	-	-	-	-	-	-	-	-	-	-	-	Entericidin
PYH2_k127_8616802_0	395495.Lcho_1675	2.675e-282	871.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,1KIWD@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
PYH2_k127_8616802_5	1038866.KB902773_gene863	8.97e-21	107.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TTJ0@28211|Alphaproteobacteria,3JS5D@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_7,dCache_1
PYH2_k127_8616941_23	864051.BurJ1DRAFT_4273	3.844e-37	144.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,1KMG3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789,ko:K14742	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
PYH2_k127_8616941_21	864051.BurJ1DRAFT_4274	3.35e-52	194.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,1KM57@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Peptidase M22, glycoprotease	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
PYH2_k127_8616941_24	864051.BurJ1DRAFT_4277	1.053e-32	140.0	COG3240@1|root,COG3240@2|Bacteria,1RI6H@1224|Proteobacteria,2VTGG@28216|Betaproteobacteria,1KM0N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	lipase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8616941_14	864051.BurJ1DRAFT_4278	4.661e-121	396.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,1KIY9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
PYH2_k127_8616941_7	1265502.KB905959_gene265	3.357e-168	537.0	COG0026@1|root,COG0026@2|Bacteria,1MU70@1224|Proteobacteria,2VI6V@28216|Betaproteobacteria,4AAU4@80864|Comamonadaceae	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)	purK	-	6.3.4.18	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07404	RC01927	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp
PYH2_k127_8616941_20	395495.Lcho_0365	7.903e-66	245.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,1KKMV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
PYH2_k127_8616941_12	864051.BurJ1DRAFT_4281	1.398e-141	460.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,1KKF3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
PYH2_k127_8616941_19	420662.Mpe_A0293	9.524e-70	252.0	COG0457@1|root,COG0457@2|Bacteria,1RGF8@1224|Proteobacteria,2VS52@28216|Betaproteobacteria,1KKV1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8616941_11	420662.Mpe_A0292	1.963e-146	471.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,1KJ3Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	phosphoribosylaminoimidazole-succinocarboxamide synthase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
PYH2_k127_8616941_4	420662.Mpe_A0291	6.512e-196	623.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,1KJFJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Fructose-bisphosphate aldolase, class II, Calvin cycle subtype	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
PYH2_k127_8616941_9	123899.JPQP01000022_gene3289	7.729e-158	510.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VKC7@28216|Betaproteobacteria,3T757@506|Alcaligenaceae	28216|Betaproteobacteria	E	Threonine dehydratase	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
PYH2_k127_8616941_3	395495.Lcho_0360	1.084e-251	782.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,1KK7K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
PYH2_k127_8616941_0	395495.Lcho_0359	0.0	1201.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,1KJ6F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
PYH2_k127_8616941_25	864051.BurJ1DRAFT_4292	1.161e-30	128.0	2E6EI@1|root,33120@2|Bacteria,1NA6C@1224|Proteobacteria,2VW1M@28216|Betaproteobacteria,1KMDA@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8616941_10	420662.Mpe_A0285	1.066e-146	467.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,1KJAQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
PYH2_k127_8616941_15	596154.Alide2_4612	4.793e-111	370.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,4AC2V@80864|Comamonadaceae	28216|Betaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
PYH2_k127_8616941_17	420662.Mpe_A0283	2.154e-81	274.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,1KKJ5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PYH2_k127_8616941_8	1265502.KB905960_gene308	2.509e-162	521.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,4AAX7@80864|Comamonadaceae	28216|Betaproteobacteria	S	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM
PYH2_k127_8616941_13	420662.Mpe_A0281	2.307e-138	450.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,1KK7C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	LU	TIGRFAM DNA protecting protein DprA	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
PYH2_k127_8616941_18	420662.Mpe_A0280	4.402e-72	246.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,1KKTZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the Smg family	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
PYH2_k127_8616941_2	864051.BurJ1DRAFT_4285	2.401e-319	993.0	COG4223@1|root,COG4223@2|Bacteria,1N10X@1224|Proteobacteria,2VNCR@28216|Betaproteobacteria,1KKHC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1631)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
PYH2_k127_8616941_5	864051.BurJ1DRAFT_4284	2.639e-172	547.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,1KJQZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
PYH2_k127_8616941_1	420662.Mpe_A0277	0.0	1020.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,1KJEI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
PYH2_k127_8616941_22	1265502.KB905960_gene314	2.767e-47	177.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,4AEH1@80864|Comamonadaceae	28216|Betaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
PYH2_k127_8616941_6	864051.BurJ1DRAFT_3701	1.751e-169	547.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VVBP@28216|Betaproteobacteria,1KNAJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PYH2_k127_8616941_26	1538295.JY96_16965	1.691e-06	62.0	COG2304@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG2304@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
PYH2_k127_8616941_16	330214.NIDE3135	1.076e-94	343.0	COG0726@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG0726@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	3.2.1.156	ko:K13735,ko:K15125,ko:K15531	ko05100,ko05133,map05100,map05133	-	-	-	ko00000,ko00001,ko00536,ko01000	-	GH8	-	DUF4347,PATR,VPEP
PYH2_k127_8625107_0	1265502.KB905942_gene2844	0.0	1252.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,4A9NT@80864|Comamonadaceae	28216|Betaproteobacteria	C	FAD linked oxidase domain protein	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
PYH2_k127_8625107_1	1223521.BBJX01000011_gene53	3.708e-250	781.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,2VH0F@28216|Betaproteobacteria,4AA3S@80864|Comamonadaceae	28216|Betaproteobacteria	G	PFAM extracellular solute-binding protein family 1	ugpB	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
PYH2_k127_8625107_2	338969.Rfer_1286	4.523e-151	481.0	COG1175@1|root,COG1175@2|Bacteria,1MVAP@1224|Proteobacteria,2VH0I@28216|Betaproteobacteria,4ACEG@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	ugpA	-	-	ko:K05814	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
PYH2_k127_8625107_3	987059.RBXJA2T_07025	1.025e-145	466.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,2VICF@28216|Betaproteobacteria,1KMFN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	probably responsible for the translocation of the substrate across the membrane	ugpE	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
PYH2_k127_8625107_4	864051.BurJ1DRAFT_1252	9.874e-138	441.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,1KKEZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system	ugpC	-	3.6.3.20	ko:K05816,ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00198,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1,3.A.1.1.3	-	-	ABC_tran,TOBE_2
PYH2_k127_8625657_4	864051.BurJ1DRAFT_4759	5.767e-16	78.0	COG0095@1|root,COG0095@2|Bacteria,1MZGC@1224|Proteobacteria,2VQIA@28216|Betaproteobacteria,1KNIZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	lipoate-protein ligase A	-	-	-	-	-	-	-	-	-	-	-	-	BPL_LplA_LipB
PYH2_k127_8625657_2	1158292.JPOE01000002_gene2344	3.522e-162	535.0	COG0508@1|root,COG0596@1|root,COG0508@2|Bacteria,COG0596@2|Bacteria,1NU1Q@1224|Proteobacteria,2VNCN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM alpha beta hydrolase fold	acoC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6,Biotin_lipoyl
PYH2_k127_8625657_0	864051.BurJ1DRAFT_4761	7.864e-199	623.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,2VKQ0@28216|Betaproteobacteria,1KK33@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Transketolase, pyrimidine binding domain	acoB	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
PYH2_k127_8625657_1	426114.THI_0482	6.802e-175	556.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,2VN57@28216|Betaproteobacteria,1KK8N@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase E1 component	acoA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
PYH2_k127_8625657_3	420662.Mpe_A1603	1.193e-28	116.0	COG1597@1|root,COG1597@2|Bacteria,1QV26@1224|Proteobacteria,2WHT0@28216|Betaproteobacteria,1KKIY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
PYH2_k127_8635977_2	595537.Varpa_5622	1.622e-64	223.0	COG0657@1|root,COG0657@2|Bacteria,1NEXK@1224|Proteobacteria,2VJSB@28216|Betaproteobacteria,4AGR7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
PYH2_k127_8635977_1	498211.CJA_0422	2.657e-76	268.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,1FHRD@10|Cellvibrio	1236|Gammaproteobacteria	S	Phosphatidylethanolamine-binding protein	ybcL	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
PYH2_k127_8635977_0	864051.BurJ1DRAFT_0860	2.538e-109	362.0	COG0679@1|root,COG0679@2|Bacteria,1MY23@1224|Proteobacteria,2VI9B@28216|Betaproteobacteria,1KJU6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PYH2_k127_8640895_6	338969.Rfer_3851	3.073e-64	224.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,2VIGZ@28216|Betaproteobacteria,4AEVE@80864|Comamonadaceae	28216|Betaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	Mur_ligase_M,PGA_cap
PYH2_k127_8640895_1	365044.Pnap_0820	3.248e-235	742.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,4AGM6@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
PYH2_k127_8640895_8	1229205.BUPH_01564	4.713e-35	142.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,1K7M3@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
PYH2_k127_8640895_3	1205680.CAKO01000008_gene4108	2.641e-105	357.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,2TQZC@28211|Alphaproteobacteria,2JQDS@204441|Rhodospirillales	204441|Rhodospirillales	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
PYH2_k127_8640895_5	189753.AXAS01000041_gene2534	1.61e-64	232.0	COG2984@1|root,COG2984@2|Bacteria,1MW5D@1224|Proteobacteria,2TSG1@28211|Alphaproteobacteria,3JSYZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PYH2_k127_8640895_2	1205680.CAKO01000037_gene1234	8.869e-161	515.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2JPY3@204441|Rhodospirillales	204441|Rhodospirillales	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_8640895_0	257310.BB1100	0.0	1259.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,3T2V3@506|Alcaligenaceae	28216|Betaproteobacteria	P	COG0474 Cation transport ATPase	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PYH2_k127_8640895_4	580332.Slit_0074	4.817e-91	308.0	COG0726@1|root,COG0726@2|Bacteria,1RG9W@1224|Proteobacteria,2VRGD@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
PYH2_k127_8640895_7	1144319.PMI16_02558	3.189e-54	198.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,2VRBT@28216|Betaproteobacteria,477JC@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Fer2_2
PYH2_k127_8656848_6	56107.Cylst_1620	2.971e-150	497.0	COG1020@1|root,COG3319@1|root,COG1020@2|Bacteria,COG3319@2|Bacteria,1G3NP@1117|Cyanobacteria,1HIUE@1161|Nostocales	1117|Cyanobacteria	Q	Thioesterase domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding,Thioesterase
PYH2_k127_8656848_12	1265502.KB905946_gene1128	1.689e-20	95.0	28WGJ@1|root,2ZIGP@2|Bacteria,1P9DI@1224|Proteobacteria,2W5VH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8656848_1	62928.azo2544	3.365e-199	625.0	COG2828@1|root,COG2828@2|Bacteria,1MXVV@1224|Proteobacteria,2VJAW@28216|Betaproteobacteria,2KY5J@206389|Rhodocyclales	206389|Rhodocyclales	S	PrpF protein	-	-	5.3.2.8	ko:K16514	ko00362,ko01120,map00362,map01120	-	R07839	RC02426	ko00000,ko00001,ko01000	-	-	-	PrpF
PYH2_k127_8656848_0	62928.azo2542	1.29e-207	671.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,2VIM3@28216|Betaproteobacteria,2KXPR@206389|Rhodocyclales	206389|Rhodocyclales	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
PYH2_k127_8656848_9	316058.RPB_0876	1.647e-121	393.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TTGT@28211|Alphaproteobacteria,3JSDX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Aldolase/RraA	ligK	-	4.1.3.17	ko:K02553,ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000,ko03019	-	-	-	RraA-like
PYH2_k127_8656848_8	1245469.S58_52600	3.245e-138	443.0	COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,2TVBS@28211|Alphaproteobacteria,3JTCY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	Domain of unknown function (DUF1932)	MA20_26655	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
PYH2_k127_8656848_2	358220.C380_22710	4.55e-189	591.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2VIDM@28216|Betaproteobacteria,4AAPG@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Amidohydrolase 2	-	-	3.1.1.57	ko:K10221	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R04277	RC03110	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
PYH2_k127_8656848_11	935863.AWZR01000001_gene1907	3.815e-81	271.0	COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,1S8CE@1236|Gammaproteobacteria,1XAYW@135614|Xanthomonadales	135614|Xanthomonadales	S	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	-	-	-	-	-	-	-	-	-	-	LigA
PYH2_k127_8656848_4	1158292.JPOE01000005_gene198	6.017e-164	519.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2VI4U@28216|Betaproteobacteria,1KKIV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ligB	-	1.13.11.57,1.13.11.8	ko:K04099,ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA,LigB
PYH2_k127_8656848_3	497321.C664_11505	2.849e-170	550.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,2VIRJ@28216|Betaproteobacteria,2KYJV@206389|Rhodocyclales	206389|Rhodocyclales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
PYH2_k127_8656848_7	1123367.C666_09800	1.05e-147	483.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2VH1Q@28216|Betaproteobacteria,2KVKF@206389|Rhodocyclales	206389|Rhodocyclales	C	oxidoreductases (related to aryl-alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PYH2_k127_8656848_10	1286631.X805_24410	6.58e-105	367.0	COG3181@1|root,COG3181@2|Bacteria,1NBZ9@1224|Proteobacteria,2VH6P@28216|Betaproteobacteria,1KNE1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_8656848_5	864051.BurJ1DRAFT_2770	2.663e-154	494.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2W9GX@28216|Betaproteobacteria,1KNPZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
PYH2_k127_8656979_1	864051.BurJ1DRAFT_2807	2.124e-111	367.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,1KKBX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
PYH2_k127_8656979_0	983917.RGE_34670	0.0	1845.0	COG1305@1|root,COG4196@1|root,COG1305@2|Bacteria,COG4196@2|Bacteria,1MVAG@1224|Proteobacteria,2VKKZ@28216|Betaproteobacteria,1KJ9V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Putative amidoligase enzyme (DUF2126)	-	-	-	-	-	-	-	-	-	-	-	-	Bact_transglu_N,DUF2126,Transglut_core
PYH2_k127_8658270_3	864051.BurJ1DRAFT_4068	8.065e-25	115.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,1KIV3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Succinyl-CoA ligase like flavodoxin domain	-	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
PYH2_k127_8658270_1	1336243.JAEA01000007_gene663	3.328e-66	236.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2U5HS@28211|Alphaproteobacteria,1JTD3@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Erythro_esteras,Pribosyltran
PYH2_k127_8658270_4	748280.NH8B_2002	1.538e-05	55.0	COG0589@1|root,COG3945@1|root,COG0589@2|Bacteria,COG3945@2|Bacteria,1MZ3K@1224|Proteobacteria,2VQ5J@28216|Betaproteobacteria	28216|Betaproteobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Usp
PYH2_k127_8658270_2	338969.Rfer_3850	6.222e-53	192.0	COG2905@1|root,COG2905@2|Bacteria,1QVY2@1224|Proteobacteria,2VT7K@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
PYH2_k127_8658270_0	1123393.KB891326_gene77	5.697e-126	420.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,1KSG6@119069|Hydrogenophilales	119069|Hydrogenophilales	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
PYH2_k127_8676023_2	864051.BurJ1DRAFT_0205	4.57e-105	348.0	COG1379@1|root,COG1379@2|Bacteria,1MVED@1224|Proteobacteria,2VJM0@28216|Betaproteobacteria,1KJW4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
PYH2_k127_8676023_0	420662.Mpe_A0246	1.899e-188	602.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,2VJ2P@28216|Betaproteobacteria,1KJEH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,SHOCT
PYH2_k127_8676023_1	1265502.KB905939_gene2373	3.298e-150	484.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria	28216|Betaproteobacteria	CH	Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
PYH2_k127_8676023_4	395495.Lcho_2225	3.366e-06	59.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1MVGQ@1224|Proteobacteria,2VHF5@28216|Betaproteobacteria,1KKIP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
PYH2_k127_8676023_5	1286631.X805_29470	0.0003443	44.0	COG1940@1|root,COG1940@2|Bacteria,1MVGQ@1224|Proteobacteria,2VHF5@28216|Betaproteobacteria,1KKIP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
PYH2_k127_8676023_3	864051.BurJ1DRAFT_0218	1.818e-76	263.0	COG0524@1|root,COG0524@2|Bacteria,1MX38@1224|Proteobacteria,2VMMY@28216|Betaproteobacteria,1KKHK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	frk	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PYH2_k127_8676545_2	1123504.JQKD01000016_gene1897	9.215e-38	148.0	COG0477@1|root,COG2814@2|Bacteria,1MVHG@1224|Proteobacteria,2VHCU@28216|Betaproteobacteria,4ABJD@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_8676545_0	713586.KB900536_gene1208	1.065e-136	477.0	COG4191@1|root,COG5000@1|root,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1WZX9@135613|Chromatiales	135613|Chromatiales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PYH2_k127_8676545_1	502025.Hoch_1823	3.663e-39	156.0	COG2267@1|root,COG2267@2|Bacteria,1R72P@1224|Proteobacteria,42W88@68525|delta/epsilon subdivisions,2WRBX@28221|Deltaproteobacteria,2YV2M@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PYH2_k127_8676545_3	1038869.AXAN01000010_gene5139	3.113e-16	85.0	COG4166@1|root,COG4166@2|Bacteria,1MUVU@1224|Proteobacteria,2VHFM@28216|Betaproteobacteria,1K1NX@119060|Burkholderiaceae	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
PYH2_k127_8686855_4	395495.Lcho_2304	1.706e-37	142.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,1KJP2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	tctA4	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
PYH2_k127_8686855_2	864051.BurJ1DRAFT_3529	1.533e-69	240.0	29717@1|root,2ZU9N@2|Bacteria,1RJ7P@1224|Proteobacteria,2VT23@28216|Betaproteobacteria,1KM1I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
PYH2_k127_8686855_0	864051.BurJ1DRAFT_3530	2.822e-273	852.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,1KJ32@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE1	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
PYH2_k127_8686855_1	420662.Mpe_A3059	7.99e-107	358.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,1KIWR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Spermidine synthase	speE1	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
PYH2_k127_8686855_3	1286631.X805_04170	3.124e-67	232.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,2VH67@28216|Betaproteobacteria,1KJHX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	TatD related DNase	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
PYH2_k127_8702764_3	864051.BurJ1DRAFT_3323	1.115e-89	302.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,1KKQX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
PYH2_k127_8702764_4	187272.Mlg_0997	1.928e-48	177.0	COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria,1WWZ5@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
PYH2_k127_8702764_5	1163617.SCD_n02705	7.552e-20	95.0	COG0316@1|root,COG0316@2|Bacteria,1N8ZN@1224|Proteobacteria,2W5FR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Iron-sulphur cluster biosynthesis	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
PYH2_k127_8702764_0	522306.CAP2UW1_2490	9.744e-104	344.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,1KQCU@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
PYH2_k127_8702764_2	864051.BurJ1DRAFT_3321	2.236e-90	317.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,1KM2G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, luxR family	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
PYH2_k127_8702764_1	864051.BurJ1DRAFT_3320	9.666e-98	327.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria,1KK5B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
PYH2_k127_8703669_0	1121440.AUMA01000011_gene2309	1.39e-135	448.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2M7WE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
PYH2_k127_8703669_2	1288494.EBAPG3_6510	5.812e-92	315.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,371QK@32003|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	rbcR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_8703669_1	1454004.AW11_03278	4.782e-100	346.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
PYH2_k127_8704294_1	570952.ATVH01000011_gene637	4.269e-155	493.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,2JVK7@204441|Rhodospirillales	204441|Rhodospirillales	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
PYH2_k127_8704294_2	1532557.JL37_17190	3.009e-23	99.0	COG0346@1|root,COG0346@2|Bacteria,1RD0N@1224|Proteobacteria,2VRUG@28216|Betaproteobacteria	28216|Betaproteobacteria	E	COG0346 Lactoylglutathione lyase and related lyases	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
PYH2_k127_8704294_0	1537715.JQFJ01000002_gene1850	2.363e-184	588.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,2TSR0@28211|Alphaproteobacteria,2JZXX@204457|Sphingomonadales	204457|Sphingomonadales	Q	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
PYH2_k127_8716065_0	365044.Pnap_3815	3.667e-09	59.0	COG1053@1|root,COG1053@2|Bacteria,1MX5A@1224|Proteobacteria,2VJUW@28216|Betaproteobacteria,4ABFK@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	cobZ	-	-	ko:K13796	-	-	-	-	ko00000	-	-	-	FAD_binding_2
PYH2_k127_8725829_2	1163617.SCD_n02018	2.201e-175	566.0	COG1055@1|root,COG1055@2|Bacteria,1PUZK@1224|Proteobacteria,2VKEF@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Involved in arsenical resistance. Thought to form the channel of an arsenite pump	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8725829_3	420662.Mpe_A1507	2.43e-137	443.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VJ0T@28216|Betaproteobacteria,1KITT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	BQ	Histone deacetylase domain	acuC	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
PYH2_k127_8725829_4	864051.BurJ1DRAFT_2214	2.962e-75	258.0	COG5490@1|root,COG5490@2|Bacteria,1R4SV@1224|Proteobacteria,2VQP2@28216|Betaproteobacteria,1KKR1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	TIGRFAM phasin family protein	phaP	-	-	-	-	-	-	-	-	-	-	-	Phasin_2
PYH2_k127_8725829_5	1265502.KB905931_gene1736	1.711e-60	211.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,4AEDX@80864|Comamonadaceae	28216|Betaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_10,Fer4_4
PYH2_k127_8725829_1	420662.Mpe_A1496	1.889e-207	648.0	COG0492@1|root,COG0492@2|Bacteria,1MW14@1224|Proteobacteria,2VGZS@28216|Betaproteobacteria,1KJ6X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Ferredoxin--NADP reductase	trxB2	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
PYH2_k127_8725829_0	1265502.KB905931_gene1734	1.124e-229	732.0	COG4773@1|root,COG4773@2|Bacteria,1NZCG@1224|Proteobacteria,2VH0X@28216|Betaproteobacteria,4AEMG@80864|Comamonadaceae	28216|Betaproteobacteria	P	TonB dependent receptor	fatA1	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
PYH2_k127_8729654_0	864051.BurJ1DRAFT_4073	1.813e-146	471.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,2VHVZ@28216|Betaproteobacteria,1KJZI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	GTP-binding signal recognition particle	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
PYH2_k127_8729654_1	420662.Mpe_A3080	2.599e-55	214.0	COG0455@1|root,COG0455@2|Bacteria,1REDF@1224|Proteobacteria,2VRXX@28216|Betaproteobacteria,1KKTU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	bacterial-type flagellum organization	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	-
PYH2_k127_8734191_6	987059.RBXJA2T_16362	1.421e-18	87.0	2E54A@1|root,32ZX9@2|Bacteria,1N8HJ@1224|Proteobacteria,2VVW9@28216|Betaproteobacteria,1KMNY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1840)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1840
PYH2_k127_8734191_3	1265502.KB905948_gene978	8.467e-175	556.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria,4AA3P@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM Cyclopropane-fatty-acyl-phospholipid synthase	mmaA3	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
PYH2_k127_8734191_0	864051.BurJ1DRAFT_4511	1.375e-223	714.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,1KJDR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_8,PAS_9,SBP_bac_3
PYH2_k127_8734191_4	987059.RBXJA2T_16372	4.602e-137	451.0	COG2206@1|root,COG2206@2|Bacteria,1N5T4@1224|Proteobacteria,2VK22@28216|Betaproteobacteria,1KK1A@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
PYH2_k127_8734191_1	864051.BurJ1DRAFT_4513	2.379e-214	675.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,1KJ7G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	pcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
PYH2_k127_8734191_2	1265502.KB905948_gene1024	1.082e-203	638.0	COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2VIVU@28216|Betaproteobacteria,4A9N6@80864|Comamonadaceae	28216|Betaproteobacteria	CH	4-hydroxybenzoate 3-monooxygenase	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
PYH2_k127_8734191_5	398578.Daci_5831	8.093e-113	392.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2VKKY@28216|Betaproteobacteria,4AAUE@80864|Comamonadaceae	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD4	-	4.2.1.82,4.2.1.9	ko:K01687,ko:K22186	ko00040,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00040,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R02429,R04441,R05070	RC00468,RC00543,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PYH2_k127_8737801_2	1038859.AXAU01000024_gene4022	7.29e-66	228.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria,3JVA6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	NMT1-like family	MA20_34190	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
PYH2_k127_8737801_0	1245469.S58_59370	3.203e-125	404.0	COG0600@1|root,COG0600@2|Bacteria,1MWDJ@1224|Proteobacteria,2TRDG@28211|Alphaproteobacteria,3JRXD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	MA20_34185	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PYH2_k127_8737801_1	420324.KI911948_gene9123	6.835e-113	389.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,1JUFY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	P	PFAM ABC transporter	MA20_34180	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
PYH2_k127_8745526_4	1538295.JY96_02280	3.211e-24	106.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,1KIXP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PYH2_k127_8745526_2	426114.THI_2202	8.591e-70	246.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,1KKKW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
PYH2_k127_8745526_0	1223521.BBJX01000012_gene566	1.763e-182	576.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,4A9JD@80864|Comamonadaceae	28216|Betaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
PYH2_k127_8745526_1	864051.BurJ1DRAFT_2958	5.472e-90	312.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,1KKJ8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
PYH2_k127_8745526_3	864051.BurJ1DRAFT_2957	4.036e-31	130.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,1KM5I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
PYH2_k127_875370_0	296591.Bpro_4647	1.104e-169	535.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,2VJGC@28216|Betaproteobacteria,4AC8V@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	-	-	1.2.7.8	ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR,TPP_enzyme_C
PYH2_k127_875370_1	983917.RGE_02870	5.836e-154	502.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria,1KJY2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	MltA specific insert domain	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
PYH2_k127_875370_5	983917.RGE_02880	4.137e-08	61.0	2EMBE@1|root,33F0E@2|Bacteria,1NHTA@1224|Proteobacteria,2VY3W@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_875370_4	1286631.X805_25140	5.47e-51	185.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,1KM27@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
PYH2_k127_875370_2	1538295.JY96_12380	6.894e-121	391.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,1KJU5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
PYH2_k127_875370_3	420662.Mpe_A1603	6.248e-109	359.0	COG1597@1|root,COG1597@2|Bacteria,1QV26@1224|Proteobacteria,2WHT0@28216|Betaproteobacteria,1KKIY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
PYH2_k127_8758315_6	1122603.ATVI01000006_gene268	1.173e-65	231.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,1RR6K@1236|Gammaproteobacteria,1X5BS@135614|Xanthomonadales	135614|Xanthomonadales	M	heptosyltransferase	opsX	-	-	ko:K12982	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
PYH2_k127_8758315_9	1437824.BN940_13436	1.307e-09	70.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VKMH@28216|Betaproteobacteria,3T24H@506|Alcaligenaceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
PYH2_k127_8758315_8	640081.Dsui_2596	2.691e-46	175.0	COG0500@1|root,COG0500@2|Bacteria,1R1AJ@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8758315_7	1117318.PRUB_10947	1.68e-49	188.0	2EB90@1|root,3359I@2|Bacteria,1Q4FD@1224|Proteobacteria,1SGFF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
PYH2_k127_8758315_3	1286631.X805_10330	4.617e-98	328.0	COG1216@1|root,COG1216@2|Bacteria,1R4ZP@1224|Proteobacteria,2VMIZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PYH2_k127_8758315_2	338969.Rfer_2083	3.185e-134	443.0	2C9BY@1|root,32IIJ@2|Bacteria,1MYQZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8758315_4	1286631.X805_10350	1.291e-94	316.0	COG2128@1|root,COG2128@2|Bacteria,1MUDM@1224|Proteobacteria,2VIMU@28216|Betaproteobacteria,1KJ5G@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
PYH2_k127_8758315_0	864051.BurJ1DRAFT_1999	2.673e-237	756.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,1KJ0P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
PYH2_k127_8758315_5	1286631.X805_10360	3.698e-88	304.0	COG1216@1|root,COG1216@2|Bacteria,1QU2Q@1224|Proteobacteria,2WGZN@28216|Betaproteobacteria,1KPMW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
PYH2_k127_8758315_1	420662.Mpe_A1346	9.444e-199	626.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,1KJYN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
PYH2_k127_875954_6	420662.Mpe_A1216	4.86e-58	204.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,1KM0J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
PYH2_k127_875954_0	420662.Mpe_A1217	0.0	1496.0	COG0823@1|root,COG0823@2|Bacteria,1R3VN@1224|Proteobacteria,2W0AD@28216|Betaproteobacteria,1KMY4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	COG0823 Periplasmic component of the Tol biopolymer transport system	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_875954_4	420662.Mpe_A1218	1.871e-79	287.0	2ESGA@1|root,33K10@2|Bacteria,1NNJA@1224|Proteobacteria,2W3CW@28216|Betaproteobacteria,1KNRV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_875954_2	420662.Mpe_A1219	1.279e-117	384.0	COG3807@1|root,COG3807@2|Bacteria,1RE8W@1224|Proteobacteria,2W17I@28216|Betaproteobacteria,1KN07@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
PYH2_k127_875954_3	420662.Mpe_A1220	3.761e-89	300.0	COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,2W2BF@28216|Betaproteobacteria,1KNIB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_875954_5	420662.Mpe_A1221	2.344e-68	240.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,2WF1B@28216|Betaproteobacteria,1KPKM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_875954_1	420662.Mpe_A1222	2.658e-155	502.0	COG2067@1|root,COG2067@2|Bacteria,1PXPC@1224|Proteobacteria	1224|Proteobacteria	I	Protein of unknown function (DUF3570)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3570
PYH2_k127_8765852_1	1458427.BAWN01000013_gene815	3.456e-58	203.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2VNF8@28216|Betaproteobacteria,4AG4P@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PYH2_k127_8765852_2	1458427.BAWN01000013_gene815	4.481e-16	78.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,2VNF8@28216|Betaproteobacteria,4AG4P@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PYH2_k127_8765852_0	1187851.A33M_2769	5.795e-195	612.0	COG4799@1|root,COG4799@2|Bacteria,1Q9BU@1224|Proteobacteria	1224|Proteobacteria	I	PFAM carboxyl transferase	gcdA	-	4.1.1.70	ko:K01615	ko00362,ko00650,ko01120,map00362,map00650,map01120	-	R03028	RC00832	ko00000,ko00001,ko01000,ko02000	3.B.1.1.3	-	-	Carboxyl_trans
PYH2_k127_8817467_7	595537.Varpa_0820	0.0001645	52.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VKKX@28216|Betaproteobacteria,4AB5R@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_8817467_6	358220.C380_11755	1.429e-108	357.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2VMBS@28216|Betaproteobacteria,4ABHD@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.22	ko:K01995,ko:K10822	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PYH2_k127_8817467_4	358220.C380_11750	1.042e-142	458.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,2VIFR@28216|Betaproteobacteria,4ADC4@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_8817467_3	358220.C380_11745	3.089e-149	475.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,2VHAJ@28216|Betaproteobacteria,4AB5H@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_8817467_0	358220.C380_11740	3.089e-217	691.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,2VJ1E@28216|Betaproteobacteria,4ACV2@80864|Comamonadaceae	28216|Betaproteobacteria	E	Extracellular liganD-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PYH2_k127_8817467_5	358220.C380_11735	8.737e-109	357.0	COG2188@1|root,COG2188@2|Bacteria,1MX3T@1224|Proteobacteria,2VHCX@28216|Betaproteobacteria,4AA5B@80864|Comamonadaceae	28216|Betaproteobacteria	K	UbiC transcription regulator-associated	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
PYH2_k127_8817467_1	395495.Lcho_3014	2.949e-172	548.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,1KJ6I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
PYH2_k127_8817467_2	864051.BurJ1DRAFT_2067	7.379e-162	527.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,1KMB7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH2_k127_8827978_3	864051.BurJ1DRAFT_4228	1.691e-49	179.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,1KM0U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
PYH2_k127_8827978_2	1265502.KB905941_gene2900	6.893e-72	246.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,2VSNM@28216|Betaproteobacteria,4ADHM@80864|Comamonadaceae	28216|Betaproteobacteria	F	phosphoribosyltransferase	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
PYH2_k127_8827978_0	395495.Lcho_3959	4.992e-183	577.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,1KIWV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
PYH2_k127_8827978_1	420662.Mpe_A0709	8.069e-176	557.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,1KJM4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Amidohydrolase family	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
PYH2_k127_8830611_1	987059.RBXJA2T_06785	5.351e-109	357.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,1KJT1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	aminotransferase class I and II	aspC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
PYH2_k127_8830611_0	1265502.KB905943_gene2723	1.085e-134	436.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,4AD1S@80864|Comamonadaceae	28216|Betaproteobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
PYH2_k127_8849364_0	1265502.KB905960_gene300	1.223e-173	552.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,4AAWR@80864|Comamonadaceae	28216|Betaproteobacteria	J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
PYH2_k127_8849364_1	420662.Mpe_A3297	3.456e-98	325.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,1KJJ1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glutathione S-transferase	gst8	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_C_3,GST_C_4,GST_N_3
PYH2_k127_8849364_2	983917.RGE_04900	1.592e-83	282.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,2VIBZ@28216|Betaproteobacteria,1KJ0U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	Epimerase,NAD_binding_10
PYH2_k127_8853489_3	420662.Mpe_A3078	3.258e-145	469.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2VHVC@28216|Betaproteobacteria,1KJHC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
PYH2_k127_8853489_4	420662.Mpe_A3077	1.414e-126	415.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,2VIH0@28216|Betaproteobacteria,1KIWM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhB	-	-	ko:K02401	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2	-	-	Bac_export_2
PYH2_k127_8853489_1	983917.RGE_17070	1.077e-153	492.0	COG1360@1|root,COG1360@2|Bacteria,1MW1Y@1224|Proteobacteria,2VHMJ@28216|Betaproteobacteria,1KK2S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Membrane MotB of proton-channel complex MotA/MotB	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
PYH2_k127_8853489_2	987059.RBXJA2T_14526	1.19e-147	473.0	COG1291@1|root,COG1291@2|Bacteria,1MXK3@1224|Proteobacteria,2VHPX@28216|Betaproteobacteria,1KJE3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	MotA/TolQ/ExbB proton channel family	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
PYH2_k127_8853489_5	395495.Lcho_0152	1.154e-101	332.0	2DBG4@1|root,2Z927@2|Bacteria,1N7I6@1224|Proteobacteria,2VQ2P@28216|Betaproteobacteria,1KJ7E@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways	flhC	-	-	ko:K02402	ko02020,ko02024,ko02026,ko02040,map02020,map02024,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlhC
PYH2_k127_8853489_6	420662.Mpe_A2869	4.192e-51	184.0	2AX91@1|root,31P80@2|Bacteria,1N25K@1224|Proteobacteria,2VSYQ@28216|Betaproteobacteria,1KM49@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways	flhD	-	-	ko:K02403	ko02020,ko02024,ko02026,ko02040,map02020,map02024,map02026,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FlhD
PYH2_k127_8853489_0	987059.RBXJA2T_13694	2.248e-196	625.0	COG4627@1|root,COG4627@2|Bacteria,1QZYD@1224|Proteobacteria,2VIYK@28216|Betaproteobacteria,1KJM8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
PYH2_k127_8853489_7	864051.BurJ1DRAFT_1314	8.907e-08	55.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,1KJFC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
PYH2_k127_8860701_6	864051.BurJ1DRAFT_2032	1.068e-98	325.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,2VMBM@28216|Betaproteobacteria,1KPHS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	adhA	-	1.1.1.1	ko:K13953,ko:K18382	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10703	RC00050,RC00087,RC00088,RC00099,RC00116,RC00545,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
PYH2_k127_8860701_5	420662.Mpe_A1803	1.258e-104	352.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,1KK6C@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
PYH2_k127_8860701_3	420662.Mpe_A1804	1.877e-179	568.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,1KJN0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_8860701_2	420662.Mpe_A1805	1.415e-188	595.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,1KJ3V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	NU	twitching motility protein	pilT2	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
PYH2_k127_8860701_4	420662.Mpe_A1806	2.442e-145	477.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,1KJWR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
PYH2_k127_8860701_1	420662.Mpe_A1807	9.297e-196	625.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,1KJJX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Aminotransferase	dapC	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PYH2_k127_8860701_8	395495.Lcho_1540	1.095e-72	261.0	COG1142@1|root,COG1142@2|Bacteria,1RIXA@1224|Proteobacteria,2VRX3@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8860701_0	395495.Lcho_1541	9.782e-261	818.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2VPQ6@28216|Betaproteobacteria	28216|Betaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
PYH2_k127_8860701_7	666681.M301_0439	2.118e-79	292.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
PYH2_k127_8871812_6	287.DR97_3417	6.968e-91	306.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,1RN3U@1236|Gammaproteobacteria,1YF0S@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
PYH2_k127_8871812_3	1095769.CAHF01000011_gene2145	4.001e-113	372.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria,472U3@75682|Oxalobacteraceae	28216|Betaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
PYH2_k127_8871812_5	365044.Pnap_1116	2.878e-93	312.0	COG4221@1|root,COG4221@2|Bacteria,1QXBX@1224|Proteobacteria,2WH93@28216|Betaproteobacteria,4AEPB@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
PYH2_k127_8871812_9	365044.Pnap_1117	3.524e-17	81.0	COG3186@1|root,COG3186@2|Bacteria,1MU29@1224|Proteobacteria,2VMHF@28216|Betaproteobacteria,4AABV@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aromatic amino acid	phhA	GO:0003674,GO:0003824,GO:0004497,GO:0004505,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016714,GO:0055114	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
PYH2_k127_8871812_8	395495.Lcho_2044	6.024e-51	190.0	COG0179@1|root,COG0179@2|Bacteria,1MW82@1224|Proteobacteria,2VJAE@28216|Betaproteobacteria,1KMZC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
PYH2_k127_8871812_1	196367.JNFG01000040_gene7980	3.223e-163	522.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,2VI9Q@28216|Betaproteobacteria,1K19V@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
PYH2_k127_8871812_10	1287116.X734_23635	5.111e-05	55.0	2AFJQ@1|root,315KK@2|Bacteria,1NDYJ@1224|Proteobacteria,2UIRQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8871812_2	1041159.AZUW01000054_gene5606	2.925e-151	501.0	COG0457@1|root,COG5616@1|root,COG0457@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Adenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
PYH2_k127_8871812_7	1349767.GJA_5128	2.492e-66	249.0	COG0457@1|root,COG0457@2|Bacteria	1349767.GJA_5128|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8871812_4	395495.Lcho_3462	1.904e-98	329.0	COG1975@1|root,COG1975@2|Bacteria,1R3RT@1224|Proteobacteria,2VKME@28216|Betaproteobacteria,1KJ5R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	TIGRFAM xanthine dehydrogenase accessory protein XdhC	xdhC	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
PYH2_k127_8871812_0	543728.Vapar_3906	0.0	1015.0	COG4631@1|root,COG4631@2|Bacteria,1NQSR@1224|Proteobacteria,2VHYR@28216|Betaproteobacteria,4AB6W@80864|Comamonadaceae	28216|Betaproteobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	xdhB	-	1.17.1.4	ko:K13482	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PYH2_k127_8899140_4	1265502.KB905930_gene1532	1.162e-52	192.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,4ABC7@80864|Comamonadaceae	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
PYH2_k127_8899140_2	420662.Mpe_A1924	1.179e-129	418.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VIHE@28216|Betaproteobacteria,1KK4T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PYH2_k127_8899140_0	864051.BurJ1DRAFT_2680	0.0	1397.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,1KITN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM Orn Lys Arg decarboxylase	adi	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
PYH2_k127_8899140_3	420662.Mpe_A1926	1.957e-58	209.0	COG1585@1|root,COG1585@2|Bacteria,1N474@1224|Proteobacteria,2VWDX@28216|Betaproteobacteria,1KM99@119065|unclassified Burkholderiales	28216|Betaproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
PYH2_k127_8899140_1	420662.Mpe_A1927	2.473e-160	526.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,1KK44@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	C-terminal region of band_7	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
PYH2_k127_8899140_5	987059.RBXJA2T_19316	5.182e-50	195.0	COG3651@1|root,COG3651@2|Bacteria,1RH68@1224|Proteobacteria,2VSN3@28216|Betaproteobacteria,1KM4X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2237)	-	-	-	ko:K09966	-	-	-	-	ko00000	-	-	-	DUF2237
PYH2_k127_8920775_1	1430440.MGMSRv2_3154	6.522e-39	164.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U26R@28211|Alphaproteobacteria,2JPQ3@204441|Rhodospirillales	204441|Rhodospirillales	M	AsmA family	-	-	-	ko:K07289,ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2
PYH2_k127_8920775_0	85643.Tmz1t_1472	1.191e-122	412.0	28HK0@1|root,2Z7V0@2|Bacteria,1MXSJ@1224|Proteobacteria,2VKGU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
PYH2_k127_8926894_10	595537.Varpa_4645	1.324e-11	64.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI98@28216|Betaproteobacteria,4AAQC@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PYH2_k127_8926894_1	1454004.AW11_03482	1.408e-242	768.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Ferrous iron transport protein B	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
PYH2_k127_8926894_11	864051.BurJ1DRAFT_4038	7.285e-05	51.0	COG0464@1|root,COG0464@2|Bacteria,1RFP5@1224|Proteobacteria	1224|Proteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,BCS1_N
PYH2_k127_8926894_7	382464.ABSI01000010_gene3722	4.568e-102	340.0	COG1028@1|root,COG1028@2|Bacteria	382464.ABSI01000010_gene3722|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8926894_3	1442599.JAAN01000019_gene2432	1.679e-195	632.0	COG3243@1|root,COG3243@2|Bacteria,1MU68@1224|Proteobacteria,1RPVQ@1236|Gammaproteobacteria,1X53T@135614|Xanthomonadales	135614|Xanthomonadales	I	Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus	-	-	-	ko:K03821	ko00650,map00650	-	R04254	RC00004	ko00000,ko00001,ko01000	-	-	-	PHBC_N,PhaC_N
PYH2_k127_8926894_0	595537.Varpa_4653	1.909e-245	762.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,2VNA3@28216|Betaproteobacteria,4AH62@80864|Comamonadaceae	28216|Betaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	4.1.1.64	ko:K00596	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_3
PYH2_k127_8926894_5	670292.JH26_01350	2.268e-126	413.0	COG2159@1|root,COG2159@2|Bacteria,1MXI7@1224|Proteobacteria,2U256@28211|Alphaproteobacteria,1JYIK@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
PYH2_k127_8926894_2	859657.RPSI07_mp0990	8.853e-204	637.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VHN0@28216|Betaproteobacteria,1K2HI@119060|Burkholderiaceae	28216|Betaproteobacteria	CE	Tartrate dehydrogenase	-	-	1.1.1.83,1.1.1.93,4.1.1.73	ko:K07246	ko00630,ko00650,map00630,map00650	-	R00215,R01751,R02545,R06180	RC00084,RC00105,RC00594	ko00000,ko00001,ko01000	-	-	-	Iso_dh
PYH2_k127_8926894_4	296591.Bpro_1433	1.509e-160	518.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VP8D@28216|Betaproteobacteria,4AGBG@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_8926894_6	375286.mma_1296	1.142e-107	353.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,2VHG8@28216|Betaproteobacteria,472KK@75682|Oxalobacteraceae	28216|Betaproteobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
PYH2_k127_8926894_8	795666.MW7_0585	5.05e-90	307.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VHK8@28216|Betaproteobacteria,1K6UF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_8926894_9	388051.AUFE01000110_gene4319	5.517e-61	223.0	COG2214@1|root,COG2214@2|Bacteria,1RDYT@1224|Proteobacteria,2VMYD@28216|Betaproteobacteria,1K52E@119060|Burkholderiaceae	28216|Betaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8939854_4	1504672.669786146	2.458e-140	457.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,4ACAA@80864|Comamonadaceae	28216|Betaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
PYH2_k127_8939854_2	365044.Pnap_1106	2.938e-233	727.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,4ABK0@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
PYH2_k127_8939854_0	365044.Pnap_1105	0.0	1185.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,4AB99@80864|Comamonadaceae	28216|Betaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
PYH2_k127_8939854_1	42256.RradSPS_0193	1.448e-285	902.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
PYH2_k127_8939854_3	1121127.JAFA01000002_gene1668	8.523e-221	709.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,2VH8E@28216|Betaproteobacteria,1K1A3@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 13 family	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
PYH2_k127_8939854_5	1504672.669786140	5.402e-46	169.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2VJUV@28216|Betaproteobacteria,4AC86@80864|Comamonadaceae	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
PYH2_k127_8953490_9	358220.C380_13670	1.184e-30	121.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,1MU2Y@1224|Proteobacteria,2VJUZ@28216|Betaproteobacteria,4A9UC@80864|Comamonadaceae	28216|Betaproteobacteria	EQ	5-oxoprolinase	oplaH	-	3.5.2.9	ko:K01469	ko00480,map00480	-	R00251	RC00553	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
PYH2_k127_8953490_6	1144342.PMI40_02259	3.998e-90	307.0	COG0697@1|root,COG0697@2|Bacteria,1R5XP@1224|Proteobacteria,2VPGM@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_8953490_5	987059.RBXJA2T_18718	1.056e-116	399.0	COG0204@1|root,COG0204@2|Bacteria,1MVWG@1224|Proteobacteria,2VI6Y@28216|Betaproteobacteria,1KN0M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Phosphate acyltransferases	yihG	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
PYH2_k127_8953490_8	887898.HMPREF0551_2224	1.41e-79	289.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VIII@28216|Betaproteobacteria,1K5V6@119060|Burkholderiaceae	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_8953490_7	123899.JPQP01000018_gene239	2.116e-84	288.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,2VN37@28216|Betaproteobacteria,3T8PH@506|Alcaligenaceae	28216|Betaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	3.5.1.68	ko:K01458	ko00340,ko00630,map00340,map00630	-	R00525	RC00165,RC00323	ko00000,ko00001,ko01000	-	-	-	FGase
PYH2_k127_8953490_0	1207063.P24_14229	4.499e-275	861.0	COG0747@1|root,COG0747@2|Bacteria,1MUP8@1224|Proteobacteria,2TQXX@28211|Alphaproteobacteria,2JZHD@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH2_k127_8953490_2	1207063.P24_14234	1.355e-158	517.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TSF3@28211|Alphaproteobacteria,2JV0Q@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PYH2_k127_8953490_4	1207063.P24_14239	1.594e-144	463.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2TTEV@28211|Alphaproteobacteria,2JVNR@204441|Rhodospirillales	204441|Rhodospirillales	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
PYH2_k127_8953490_3	1121861.KB899930_gene198	1.269e-156	511.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales	204441|Rhodospirillales	EP	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
PYH2_k127_8953490_1	1207063.P24_14249	1.496e-171	559.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,2JPRD@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
PYH2_k127_8953490_10	693444.D782_3141	1.04e-08	66.0	COG2039@1|root,COG2039@2|Bacteria,1MWYG@1224|Proteobacteria,1RPYK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Removes 5-oxoproline from various penultimate amino acid residues except L-proline	pcp	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	3.4.19.3	ko:K01304	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C15
PYH2_k127_8967244_11	1502852.FG94_04161	7.328e-39	148.0	COG2267@1|root,COG2267@2|Bacteria,1Q6AF@1224|Proteobacteria,2VJQ3@28216|Betaproteobacteria,472AB@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,FSH1
PYH2_k127_8967244_2	1265502.KB905936_gene2642	1.777e-232	725.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,4AB52@80864|Comamonadaceae	28216|Betaproteobacteria	E	TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PYH2_k127_8967244_7	864051.BurJ1DRAFT_0843	1.795e-73	250.0	COG0517@1|root,COG0517@2|Bacteria,1N0H3@1224|Proteobacteria,2VQEB@28216|Betaproteobacteria,1KKNW@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
PYH2_k127_8967244_4	1265502.KB905936_gene2640	3.679e-196	619.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,4AADA@80864|Comamonadaceae	28216|Betaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
PYH2_k127_8967244_13	420662.Mpe_A2058	6.184e-32	129.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,1KPJS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
PYH2_k127_8967244_12	864051.BurJ1DRAFT_3125	9.096e-34	139.0	2FEFF@1|root,346F4@2|Bacteria,1NZUX@1224|Proteobacteria,2W4QF@28216|Betaproteobacteria,1KNVR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8967244_1	1265502.KB905936_gene2627	1.413e-246	766.0	COG1760@1|root,COG1760@2|Bacteria,1MUZN@1224|Proteobacteria,2VH8K@28216|Betaproteobacteria,4AA7J@80864|Comamonadaceae	28216|Betaproteobacteria	E	serine dehydratase beta chain	sdaA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
PYH2_k127_8967244_10	1121352.JHZP01000001_gene537	8.565e-53	198.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,2WERU@28216|Betaproteobacteria,2KRVT@206351|Neisseriales	206351|Neisseriales	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
PYH2_k127_8967244_0	420662.Mpe_A1431	0.0	1527.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,1KJKP@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
PYH2_k127_8967244_9	864051.BurJ1DRAFT_3586	7.615e-59	215.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,1KM0D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
PYH2_k127_8967244_5	395495.Lcho_1561	9.178e-176	557.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,1KJGF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Glycine cleavage system T protein	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
PYH2_k127_8967244_8	864051.BurJ1DRAFT_3584	2.332e-67	235.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	coa-binding	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
PYH2_k127_8967244_3	864051.BurJ1DRAFT_3583	1.363e-228	713.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2VHYA@28216|Betaproteobacteria,1KJP9@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	PFAM Cys Met metabolism	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PYH2_k127_8967244_6	1157708.KB907455_gene3400	2.154e-172	559.0	COG1502@1|root,COG1502@2|Bacteria,1MUDJ@1224|Proteobacteria,2VHSI@28216|Betaproteobacteria,4AAIW@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Phospholipase D Transphosphatidylase	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PYH2_k127_8973309_1	1265502.KB905929_gene2146	9.811e-14	77.0	COG2882@1|root,COG2882@2|Bacteria,1N819@1224|Proteobacteria,2VWDT@28216|Betaproteobacteria,4AFPA@80864|Comamonadaceae	28216|Betaproteobacteria	N	Flagellar FliJ protein	-	-	-	ko:K02413	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliJ
PYH2_k127_8973309_0	864051.BurJ1DRAFT_0261	1.33e-187	589.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,2VHQ5@28216|Betaproteobacteria,1KIVI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Flagellar protein export ATPase FliI	fliI	-	3.6.3.14	ko:K02412	ko02040,map02040	-	-	-	ko00000,ko00001,ko01000,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
PYH2_k127_8976400_4	864051.BurJ1DRAFT_2953	2.196e-22	99.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,1KK5S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
PYH2_k127_8976400_2	983917.RGE_27540	6.114e-83	284.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,1KKMF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
PYH2_k127_8976400_1	987059.RBXJA2T_17921	5.275e-205	649.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,1KJ7J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
PYH2_k127_8976400_0	420662.Mpe_A1996	2.703e-224	700.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,1KK5J@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
PYH2_k127_8976400_3	864051.BurJ1DRAFT_2957	3.912e-25	108.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,1KM5I@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
PYH2_k127_8978597_1	864051.BurJ1DRAFT_3335	4.304e-119	411.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
PYH2_k127_8978597_0	864051.BurJ1DRAFT_3336	2.684e-263	814.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	sulfite reductase, dissimilatory-type alpha subunit	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
PYH2_k127_8978597_2	864051.BurJ1DRAFT_3337	1.061e-23	103.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8989756_2	1123504.JQKD01000002_gene3997	8.398e-60	209.0	COG5476@1|root,COG5476@2|Bacteria,1MX4P@1224|Proteobacteria,2VJ0J@28216|Betaproteobacteria,4AD4F@80864|Comamonadaceae	28216|Betaproteobacteria	E	Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1485,MlrC_C
PYH2_k127_8989756_0	864051.BurJ1DRAFT_4606	3.102e-188	603.0	COG0747@1|root,COG0747@2|Bacteria,1MWBH@1224|Proteobacteria,2VHY1@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Extracellular solute-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH2_k127_8989756_1	1231391.AMZF01000009_gene1749	2.152e-132	428.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VJJU@28216|Betaproteobacteria,3T8WN@506|Alcaligenaceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_8993189_14	1265502.KB905935_gene3103	3.435e-17	89.0	COG2887@1|root,COG2887@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria,4AB66@80864|Comamonadaceae	28216|Betaproteobacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
PYH2_k127_8993189_10	864051.BurJ1DRAFT_2470	1.434e-60	210.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,1KM5F@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PYH2_k127_8993189_1	420662.Mpe_A1282	2.428e-250	775.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,1KJE2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
PYH2_k127_8993189_13	983917.RGE_33110	4.706e-46	169.0	COG0254@1|root,COG0254@2|Bacteria,1MZ4D@1224|Proteobacteria,2VU3I@28216|Betaproteobacteria,1KMAZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL31 family	rpmE2	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
PYH2_k127_8993189_2	1265502.KB905935_gene3107	1.331e-201	646.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,4A9MR@80864|Comamonadaceae	28216|Betaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	arnT	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_8993189_3	420662.Mpe_A1278	7.548e-183	597.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,1KJ2K@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	TIGRFAM phosphate regulon sensor kinase PhoR	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
PYH2_k127_8993189_8	420662.Mpe_A1277	8.394e-110	367.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,1KIU0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	K	phosphate regulon transcriptional regulatory protein PhoB	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PYH2_k127_8993189_9	420662.Mpe_A1276	2.62e-107	363.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,1KIW3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
PYH2_k127_8993189_7	395495.Lcho_1657	1.501e-149	476.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,1KK41@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
PYH2_k127_8993189_5	395495.Lcho_1656	1.012e-161	516.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,2VH6Y@28216|Betaproteobacteria,1KNU3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
PYH2_k127_8993189_6	395495.Lcho_1655	2.827e-150	482.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,1KNKG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
PYH2_k127_8993189_4	395495.Lcho_1654	3.036e-167	531.0	COG0226@1|root,COG0226@2|Bacteria,1MUH9@1224|Proteobacteria,2VKAU@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TIGRFAM phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like,PBP_like_2
PYH2_k127_8993189_0	1123504.JQKD01000002_gene3546	7.53e-276	864.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,4A9NH@80864|Comamonadaceae	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
PYH2_k127_8993189_11	987059.RBXJA2T_09372	2.932e-52	190.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,1KM0H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
PYH2_k127_8993189_12	1349767.GJA_4042	3.151e-51	191.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2VM3G@28216|Betaproteobacteria,473UX@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
PYH2_k127_8993219_0	414684.RC1_3562	0.0	1030.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2TR38@28211|Alphaproteobacteria,2JR8S@204441|Rhodospirillales	204441|Rhodospirillales	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
PYH2_k127_9014745_2	983917.RGE_14070	1.288e-49	181.0	COG1960@1|root,COG1960@2|Bacteria,1MUBH@1224|Proteobacteria,2VHX0@28216|Betaproteobacteria,1KJJR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_9014745_0	864051.BurJ1DRAFT_3855	2.217e-218	685.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2VIQT@28216|Betaproteobacteria,1KK7B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
PYH2_k127_9014745_1	864051.BurJ1DRAFT_3854	3.92e-67	233.0	COG2271@1|root,COG2271@2|Bacteria,1QVKZ@1224|Proteobacteria,2WHHX@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_9015814_1	864051.BurJ1DRAFT_2950	4.024e-171	550.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,1KJBX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
PYH2_k127_9015814_3	1265502.KB905935_gene3059	6.206e-41	153.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,4AEZ7@80864|Comamonadaceae	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
PYH2_k127_9015814_0	420662.Mpe_A1992	5.041e-227	713.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,1KJJ0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
PYH2_k127_9015814_2	864051.BurJ1DRAFT_2953	9.663e-122	396.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,1KK5S@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
PYH2_k127_9015905_1	420662.Mpe_A3737	4.545e-218	684.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,1KJNN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
PYH2_k127_9015905_2	1265502.KB905944_gene690	6.974e-162	526.0	COG0583@1|root,COG0583@2|Bacteria,1MVA1@1224|Proteobacteria,2VIBJ@28216|Betaproteobacteria,4A9KZ@80864|Comamonadaceae	28216|Betaproteobacteria	K	Transcriptional regulator	oxyR	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
PYH2_k127_9015905_3	1223521.BBJX01000013_gene378	9.543e-81	273.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,4ABZ5@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the Dps family	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
PYH2_k127_9015905_4	1245471.PCA10_34820	2.442e-74	255.0	COG0693@1|root,COG0693@2|Bacteria,1MYS4@1224|Proteobacteria,1RZUY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	DJ-1 PfpI family protein	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
PYH2_k127_9015905_5	748247.AZKH_p0027	1.34e-66	238.0	COG3248@1|root,COG3248@2|Bacteria,1RB5M@1224|Proteobacteria	1224|Proteobacteria	M	Nucleoside-binding outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Channel_Tsx,DUF5020
PYH2_k127_9015905_0	987059.RBXJA2T_05188	3.086e-294	909.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2VIV3@28216|Betaproteobacteria,1KIZE@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
PYH2_k127_9017084_5	864051.BurJ1DRAFT_4216	6.856e-58	208.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,1KM58@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	PFAM Phosphoribosyltransferase	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
PYH2_k127_9017084_4	987059.RBXJA2T_00120	3.801e-65	231.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,1KKJI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
PYH2_k127_9017084_1	420662.Mpe_A0717	1.062e-127	416.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,1KJ5M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
PYH2_k127_9017084_3	864051.BurJ1DRAFT_4219	5.451e-70	240.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,1KKTQ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
PYH2_k127_9017084_7	1538295.JY96_07355	1.664e-34	139.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,1KM9Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
PYH2_k127_9017084_6	420662.Mpe_A0714	3.599e-45	167.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,1KM9T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	glpE	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
PYH2_k127_9017084_0	987059.RBXJA2T_00150	1.075e-130	420.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,2VHEK@28216|Betaproteobacteria,1KJZT@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
PYH2_k127_9017084_2	1265502.KB905941_gene2897	4.168e-83	285.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,4AB54@80864|Comamonadaceae	28216|Betaproteobacteria	I	PFAM Phospholipid glycerol acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PYH2_k127_9017084_8	420662.Mpe_A0709	7.338e-15	75.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,1KJM4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Amidohydrolase family	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
PYH2_k127_9021919_1	1156935.QWE_07766	3.362e-39	156.0	COG0154@1|root,COG0154@2|Bacteria,1MWWQ@1224|Proteobacteria,2TSN9@28211|Alphaproteobacteria,4B8YD@82115|Rhizobiaceae	28211|Alphaproteobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
PYH2_k127_9021919_0	1121861.KB899924_gene3568	8.999e-181	581.0	COG4948@1|root,COG4948@2|Bacteria,1MV2S@1224|Proteobacteria,2TTFB@28211|Alphaproteobacteria,2JVX4@204441|Rhodospirillales	204441|Rhodospirillales	M	Mandelate Racemase Muconate Lactonizing	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C
PYH2_k127_9021919_2	1411123.JQNH01000001_gene3165	1.419e-36	139.0	COG1082@1|root,COG1082@2|Bacteria,1R87Z@1224|Proteobacteria,2U45F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
PYH2_k127_9024405_6	1123020.AUIE01000003_gene654	1.443e-44	163.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,1RN2C@1236|Gammaproteobacteria,1YDB4@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
PYH2_k127_9024405_5	365046.Rta_28880	1.412e-51	190.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2VSD1@28216|Betaproteobacteria,4AEND@80864|Comamonadaceae	28216|Betaproteobacteria	K	TIGRFAM Cu(I)-responsive transcriptional regulator	cueR	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind
PYH2_k127_9024405_7	28072.Nos7524_1820	5.514e-42	156.0	COG1324@1|root,COG1324@2|Bacteria,1G7PJ@1117|Cyanobacteria,1HP9B@1161|Nostocales	1117|Cyanobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
PYH2_k127_9024405_4	1265502.KB905954_gene417	6.227e-87	293.0	COG2863@1|root,COG2863@2|Bacteria,1MZU1@1224|Proteobacteria,2VU50@28216|Betaproteobacteria,4AAKY@80864|Comamonadaceae	28216|Betaproteobacteria	C	Cytochrome c class I	cytC2	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
PYH2_k127_9024405_1	1123504.JQKD01000021_gene5700	3.813e-166	524.0	COG0714@1|root,COG0714@2|Bacteria,1MV5I@1224|Proteobacteria,2VH9H@28216|Betaproteobacteria,4A9TQ@80864|Comamonadaceae	28216|Betaproteobacteria	S	ATPase associated with various cellular activities, AAA_5	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
PYH2_k127_9024405_3	864051.BurJ1DRAFT_1409	4.543e-92	306.0	COG1670@1|root,COG1670@2|Bacteria,1MXEE@1224|Proteobacteria,2VKTD@28216|Betaproteobacteria,1KJ0Q@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
PYH2_k127_9024405_0	864051.BurJ1DRAFT_1406	1.628e-234	729.0	COG3825@1|root,COG3825@2|Bacteria,1MUAJ@1224|Proteobacteria,2VJ99@28216|Betaproteobacteria,1KJD4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	ko:K09989	-	-	-	-	ko00000	-	-	-	VWA_CoxE
PYH2_k127_9024405_2	1205680.CAKO01000002_gene3078	1.973e-157	504.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2JPND@204441|Rhodospirillales	204441|Rhodospirillales	P	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PYH2_k127_9035972_5	864051.BurJ1DRAFT_2673	4.649e-30	122.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,1KK3D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
PYH2_k127_9035972_0	1158292.JPOE01000002_gene1867	0.0	1043.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,1KJBB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
PYH2_k127_9035972_3	987059.RBXJA2T_19271	1.123e-108	361.0	COG0697@1|root,COG0697@2|Bacteria,1RFZW@1224|Proteobacteria,2VJS5@28216|Betaproteobacteria,1KJ5V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PYH2_k127_9035972_1	1122603.ATVI01000008_gene2252	2.448e-242	772.0	COG2759@1|root,COG2759@2|Bacteria,1MUR8@1224|Proteobacteria,1RME6@1236|Gammaproteobacteria,1X97G@135614|Xanthomonadales	135614|Xanthomonadales	F	Formate--tetrahydrofolate ligase	-	-	-	-	-	-	-	-	-	-	-	-	FTHFS
PYH2_k127_9035972_2	864051.BurJ1DRAFT_2670	8.657e-161	523.0	COG1020@1|root,COG1020@2|Bacteria,1N7HY@1224|Proteobacteria,2VMJZ@28216|Betaproteobacteria,1KN20@119065|unclassified Burkholderiales	28216|Betaproteobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
PYH2_k127_9035972_4	983917.RGE_26410	1.616e-83	283.0	COG2267@1|root,COG2267@2|Bacteria,1R41P@1224|Proteobacteria,2VNV3@28216|Betaproteobacteria,1KNAN@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
PYH2_k127_9040147_0	864051.BurJ1DRAFT_4072	1.701e-189	595.0	COG1298@1|root,COG1298@2|Bacteria,1MUF3@1224|Proteobacteria,2VHVC@28216|Betaproteobacteria,1KJHC@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	flhA	-	-	ko:K02400	ko02040,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FHIPEP
PYH2_k127_9040147_1	983917.RGE_17120	1.256e-30	124.0	COG1419@1|root,COG1419@2|Bacteria,1MUQW@1224|Proteobacteria,2VHVZ@28216|Betaproteobacteria,1KJZI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	N	GTP-binding signal recognition particle	flhF	-	-	ko:K02404	-	-	-	-	ko00000,ko02035	-	-	-	SRP54
PYH2_k127_9049481_8	266265.Bxe_C0034	1.309e-73	251.0	COG3552@1|root,COG3552@2|Bacteria,1MUHH@1224|Proteobacteria,2VNH5@28216|Betaproteobacteria,1K1YF@119060|Burkholderiaceae	28216|Betaproteobacteria	S	VWA domain containing CoxE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	VWA_CoxE
PYH2_k127_9049481_6	1100721.ALKO01000018_gene1170	7.164e-93	315.0	COG1975@1|root,COG1975@2|Bacteria,1MWFN@1224|Proteobacteria,2VX75@28216|Betaproteobacteria	28216|Betaproteobacteria	O	XdhC and CoxI family	-	-	-	-	-	-	-	-	-	-	-	-	XdhC_C,XdhC_CoxI
PYH2_k127_9049481_7	1100721.ALKO01000018_gene1169	3.25e-90	302.0	COG2068@1|root,COG2068@2|Bacteria,1MW0X@1224|Proteobacteria,2VT4G@28216|Betaproteobacteria,4AERD@80864|Comamonadaceae	28216|Betaproteobacteria	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
PYH2_k127_9049481_5	864051.BurJ1DRAFT_3431	3.339e-122	399.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VKRU@28216|Betaproteobacteria,1KKDY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
PYH2_k127_9049481_9	987059.RBXJA2T_16912	1.613e-70	240.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,1KKT3@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
PYH2_k127_9049481_1	365046.Rta_03610	2.505e-278	860.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,4AAUZ@80864|Comamonadaceae	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
PYH2_k127_9049481_3	420662.Mpe_A0196	7.9e-142	454.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,1KKE4@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
PYH2_k127_9049481_0	987059.RBXJA2T_16897	2.106e-308	948.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,1KJ5T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
PYH2_k127_9049481_11	395495.Lcho_3529	1.759e-54	197.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,1KKV0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
PYH2_k127_9049481_10	864051.BurJ1DRAFT_0315	2.396e-59	211.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,1KKTM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
PYH2_k127_9049481_13	987059.RBXJA2T_16882	4.228e-38	145.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria,1KMBR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
PYH2_k127_9049481_4	987059.RBXJA2T_16877	6.722e-133	429.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,1KJR2@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
PYH2_k127_9049481_12	420662.Mpe_A0190	3.636e-38	148.0	COG3312@1|root,COG3312@2|Bacteria,1RJ13@1224|Proteobacteria,2VT87@28216|Betaproteobacteria,1KM6R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
PYH2_k127_9049481_2	1458275.AZ34_06815	5.351e-144	465.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,2VKI0@28216|Betaproteobacteria,4AA08@80864|Comamonadaceae	28216|Betaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
PYH2_k127_9049481_14	983917.RGE_02320	1.532e-29	119.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,1KJK1@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
PYH2_k127_9055040_2	1392838.AWNM01000037_gene1054	2.585e-27	114.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,3T309@506|Alcaligenaceae	28216|Betaproteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_9055040_1	420662.Mpe_A1751	1.607e-161	514.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,1KJGJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_9055040_0	395495.Lcho_2033	4.4e-323	1000.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,1KJH8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
PYH2_k127_9070037_5	1408164.MOLA814_02057	3.335e-51	184.0	COG2084@1|root,COG2084@2|Bacteria,1MUD0@1224|Proteobacteria,2VKIK@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Dehydrogenase	-	-	1.1.1.31,1.1.1.411	ko:K00020,ko:K08319	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
PYH2_k127_9070037_2	987059.RBXJA2T_04313	1.152e-137	470.0	COG0784@1|root,COG2202@1|root,COG4251@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,1NC9X@1224|Proteobacteria,2WHTA@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_7,Response_reg
PYH2_k127_9070037_1	365046.Rta_18290	1.634e-185	583.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,2VJ6S@28216|Betaproteobacteria,4AA2B@80864|Comamonadaceae	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	acdS	-	3.5.99.7,4.4.1.15,4.4.1.25	ko:K01505,ko:K05396,ko:K17950	ko00270,map00270	-	R00997,R01874,R07634	RC00382,RC00419,RC01784	ko00000,ko00001,ko01000	-	-	-	PALP
PYH2_k127_9070037_4	864051.BurJ1DRAFT_3886	1.331e-58	211.0	2AN43@1|root,31D1U@2|Bacteria,1RICI@1224|Proteobacteria,2VT3P@28216|Betaproteobacteria,1KM1P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_9070037_3	864051.BurJ1DRAFT_3887	4.4e-119	387.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,2VIXS@28216|Betaproteobacteria,1KNH5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	IQ	KR domain	kduD	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
PYH2_k127_9070037_0	864051.BurJ1DRAFT_3894	0.0	1064.0	COG0129@1|root,COG0129@2|Bacteria,1MV4I@1224|Proteobacteria,2W9CY@28216|Betaproteobacteria,1KNBF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EG	Belongs to the IlvD Edd family	-	-	4.2.1.82	ko:K22186	ko00040,map00040	-	R02429	RC00543	ko00000,ko00001,ko01000	-	-	-	ILVD_EDD
PYH2_k127_9070037_6	543728.Vapar_3755	1.154e-25	109.0	COG0624@1|root,COG0624@2|Bacteria,1MW2W@1224|Proteobacteria,2VK08@28216|Betaproteobacteria,4ADDT@80864|Comamonadaceae	28216|Betaproteobacteria	E	Peptidase dimerisation domain	-	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
PYH2_k127_9070407_3	1123229.AUBC01000013_gene2606	5.128e-34	136.0	COG2268@1|root,COG2268@2|Bacteria,1P50K@1224|Proteobacteria,2TTVY@28211|Alphaproteobacteria,3JTXC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Flotillin	MA20_29840	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
PYH2_k127_9070407_0	388739.RSK20926_00750	3.961e-153	496.0	COG0683@1|root,COG0683@2|Bacteria,1MUZU@1224|Proteobacteria,2TS7Z@28211|Alphaproteobacteria,2P57V@2433|Roseobacter	28211|Alphaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_5
PYH2_k127_9070407_1	83219.PM02_16385	7.652e-112	368.0	COG0559@1|root,COG0559@2|Bacteria,1MVND@1224|Proteobacteria,2TRMA@28211|Alphaproteobacteria,3ZVBV@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PYH2_k127_9070407_2	314270.RB2083_1522	4.035e-98	356.0	COG4177@1|root,COG4177@2|Bacteria,1MWRD@1224|Proteobacteria,2TS03@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
PYH2_k127_9116818_1	1449049.JONW01000008_gene520	7.522e-07	57.0	2E5SP@1|root,330H2@2|Bacteria,1Q9TH@1224|Proteobacteria,2UGZT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
PYH2_k127_9116818_0	1380391.JIAS01000006_gene2539	7.707e-31	132.0	COG2982@1|root,COG2982@2|Bacteria,1MUAN@1224|Proteobacteria,2U26R@28211|Alphaproteobacteria,2JPQ3@204441|Rhodospirillales	204441|Rhodospirillales	M	AsmA family	-	-	-	ko:K07289,ko:K07290	-	-	-	-	ko00000	9.B.121	-	-	AsmA,AsmA_2
PYH2_k127_9165107_0	477184.KYC_01829	3.058e-152	486.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VJNE@28216|Betaproteobacteria,3T5YB@506|Alcaligenaceae	28216|Betaproteobacteria	C	3-isopropylmalate dehydratase large subunit	leuC1	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
PYH2_k127_9165107_1	1157708.KB907459_gene2137	9.049e-114	370.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VKKX@28216|Betaproteobacteria,4AB5R@80864|Comamonadaceae	28216|Betaproteobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PYH2_k127_917613_0	1265502.KB905934_gene3223	2.023e-237	742.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,4A9Z5@80864|Comamonadaceae	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
PYH2_k127_917613_2	1265502.KB905934_gene3224	7.453e-89	299.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,4AAAK@80864|Comamonadaceae	28216|Betaproteobacteria	E	HAD-superfamily hydrolase, subfamily IB, PSPase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD
PYH2_k127_917613_3	983917.RGE_13380	8.166e-77	266.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,1KKNJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Belongs to the DnaA family	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
PYH2_k127_917613_1	420662.Mpe_A3024	3.274e-123	403.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,2VMIR@28216|Betaproteobacteria,1KKIU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
PYH2_k127_917613_4	395495.Lcho_0670	5.565e-08	55.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,1KK6B@119065|unclassified Burkholderiales	28216|Betaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
PYH2_k127_920106_7	767817.Desgi_1127	3.396e-06	49.0	COG0674@1|root,COG0674@2|Bacteria,1VS48@1239|Firmicutes,25E5U@186801|Clostridia,261NS@186807|Peptococcaceae	186801|Clostridia	C	2-oxoacid ferredoxin oxidoreductase, alpha subunit	porA	GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.2.7.1,1.2.7.10	ko:K00169,ko:K19070	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
PYH2_k127_920106_1	1232410.KI421423_gene1909	2.421e-105	352.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,43UKU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1	ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
PYH2_k127_920106_8	449447.MAE_04350	0.0004845	45.0	2C1SS@1|root,32YN6@2|Bacteria,1G9HK@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_920106_4	153948.NAL212_0565	4.365e-11	66.0	2E90H@1|root,3339X@2|Bacteria,1PZ36@1224|Proteobacteria,2W6KH@28216|Betaproteobacteria,374DK@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_920106_5	864051.BurJ1DRAFT_3207	5.854e-08	55.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,2VQRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
PYH2_k127_920106_0	1121106.JQKB01000010_gene445	8.079e-148	477.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,2JRVP@204441|Rhodospirillales	204441|Rhodospirillales	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253	ko00980,ko04976,ko05204,map00980,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
PYH2_k127_920106_3	1217718.ALOU01000047_gene3800	1.56e-11	71.0	2E7II@1|root,3320V@2|Bacteria,1N91Y@1224|Proteobacteria,2VW18@28216|Betaproteobacteria,1K8QZ@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_920106_2	1255043.TVNIR_2999	2.135e-92	325.0	COG0457@1|root,COG0457@2|Bacteria,1N01S@1224|Proteobacteria,1S0RI@1236|Gammaproteobacteria,1X05M@135613|Chromatiales	135613|Chromatiales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_9253345_4	983917.RGE_38500	2.707e-56	199.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,1KKVU@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
PYH2_k127_9253345_2	864051.BurJ1DRAFT_3775	8.072e-68	241.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,1KM1Y@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PYH2_k127_9253345_0	987059.RBXJA2T_00245	5.951e-159	510.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,1KJMH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
PYH2_k127_9253345_3	1100721.ALKO01000003_gene2175	1.022e-59	216.0	COG0204@1|root,COG0204@2|Bacteria,1RJMS@1224|Proteobacteria,2VT33@28216|Betaproteobacteria,4AEK7@80864|Comamonadaceae	28216|Betaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
PYH2_k127_9253345_1	864051.BurJ1DRAFT_3778	4.073e-154	492.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,1KJD8@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
PYH2_k127_9265619_0	864051.BurJ1DRAFT_2232	1.908e-283	875.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,1KIY6@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Dehydrogenase	lpdA	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
PYH2_k127_9268224_7	395495.Lcho_1908	8.406e-08	56.0	COG2366@1|root,COG2366@2|Bacteria,1MVMH@1224|Proteobacteria,2VIWI@28216|Betaproteobacteria,1KM79@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Penicillin amidase	-	-	3.5.1.11	ko:K01434	ko00311,ko01130,map00311,map01130	-	R02170	RC00166,RC00328	ko00000,ko00001,ko01000,ko01002	-	-	-	Penicil_amidase
PYH2_k127_9268224_4	864051.BurJ1DRAFT_1972	5.392e-55	198.0	COG3812@1|root,COG3812@2|Bacteria,1RGUV@1224|Proteobacteria,2VS54@28216|Betaproteobacteria,1KM4Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1993)	-	-	-	ko:K09983	-	-	-	-	ko00000	-	-	-	DUF1993
PYH2_k127_9268224_0	864051.BurJ1DRAFT_1971	7.36e-182	572.0	COG0111@1|root,COG0111@2|Bacteria,1MW0R@1224|Proteobacteria,2VHIZ@28216|Betaproteobacteria,1KJI5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PYH2_k127_9268224_2	1286631.X805_41330	1.569e-140	472.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VITW@28216|Betaproteobacteria,1KJ4U@119065|unclassified Burkholderiales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PYH2_k127_9268224_3	864051.BurJ1DRAFT_1969	4.826e-60	213.0	COG2059@1|root,COG2059@2|Bacteria,1MZHQ@1224|Proteobacteria,2VQS5@28216|Betaproteobacteria,1KM4R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
PYH2_k127_9268224_5	76114.ebA4644	3.396e-53	201.0	COG2059@1|root,COG2059@2|Bacteria,1RAZW@1224|Proteobacteria,2VQ9R@28216|Betaproteobacteria,2KW68@206389|Rhodocyclales	206389|Rhodocyclales	P	Chromate transporter	chrA	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
PYH2_k127_9268224_6	522306.CAP2UW1_2715	3.662e-09	60.0	2CIC8@1|root,33JK4@2|Bacteria,1NH5Z@1224|Proteobacteria,2VYDU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_9268224_1	864051.BurJ1DRAFT_2871	1.008e-153	501.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2VIKH@28216|Betaproteobacteria,1KKYK@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	imuB	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
PYH2_k127_9268816_1	1502851.FG93_06077	3.368e-54	199.0	COG0760@1|root,COG0760@2|Bacteria,1R4ZR@1224|Proteobacteria,2U874@28211|Alphaproteobacteria,3JRK1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
PYH2_k127_9268816_0	395492.Rleg2_5109	1.392e-87	306.0	COG2370@1|root,COG2370@2|Bacteria,1MV6Z@1224|Proteobacteria,2TSX2@28211|Alphaproteobacteria,4BA0J@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	HupE / UreJ protein	-	-	-	-	-	-	-	-	-	-	-	-	HupE_UreJ_2
PYH2_k127_9275039_1	1297865.APJD01000005_gene3518	8.089e-150	479.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TR0N@28211|Alphaproteobacteria,3JUIB@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	MA20_16775	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PYH2_k127_9275039_0	1380394.JADL01000008_gene3592	1.21e-184	601.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TR1D@28211|Alphaproteobacteria,2JVA4@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PYH2_k127_9275039_2	1380394.JADL01000008_gene3593	9.304e-146	468.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,2TQTV@28211|Alphaproteobacteria,2JPRD@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
PYH2_k127_9295458_0	365044.Pnap_1249	5.946e-172	545.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9PT@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
PYH2_k127_9295458_1	1276756.AUEX01000018_gene3003	1.088e-159	513.0	COG1541@1|root,COG1541@2|Bacteria,1P22K@1224|Proteobacteria,2WGC2@28216|Betaproteobacteria,4ACC7@80864|Comamonadaceae	28216|Betaproteobacteria	H	coenzyme F390 synthetase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
PYH2_k127_946184_3	864051.BurJ1DRAFT_3686	6.566e-20	92.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,1KM7T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Belongs to the UPF0307 family	yjgA	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
PYH2_k127_946184_1	864051.BurJ1DRAFT_3687	5.141e-98	325.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,1KJPI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	molybdenum cofactor	mogA	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
PYH2_k127_946184_0	1286631.X805_38120	6.215e-135	433.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,1KK2Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	serine O-acetyltransferase	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
PYH2_k127_946184_2	983917.RGE_15180	3.102e-84	282.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,1KKBY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
PYH2_k127_947750_0	426114.THI_0805	1.16e-299	921.0	COG2987@1|root,COG2987@2|Bacteria,1MU4W@1224|Proteobacteria,2VK3E@28216|Betaproteobacteria,1KMZR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
PYH2_k127_947750_1	426114.THI_0804	4.478e-83	280.0	COG2986@1|root,COG2986@2|Bacteria,1MU6K@1224|Proteobacteria,2VJB1@28216|Betaproteobacteria,1KMXV@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
PYH2_k127_961317_9	864051.BurJ1DRAFT_2820	4.013e-13	72.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VI23@28216|Betaproteobacteria,1KMWM@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
PYH2_k127_961317_4	365044.Pnap_0077	6.132e-159	511.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,4AJ83@80864|Comamonadaceae	28216|Betaproteobacteria	NU	twitching motility protein	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
PYH2_k127_961317_1	864051.BurJ1DRAFT_2821	1.987e-244	760.0	COG0015@1|root,COG0015@2|Bacteria,1MXNN@1224|Proteobacteria,2VID3@28216|Betaproteobacteria,1KKNG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Adenylosuccinate lyase C-terminus	-	-	5.5.1.2	ko:K01857	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03307	RC00902	ko00000,ko00001,ko01000	-	-	-	ADSL_C,Lyase_1
PYH2_k127_961317_2	864051.BurJ1DRAFT_2822	1.154e-215	674.0	COG1804@1|root,COG1804@2|Bacteria,1MU4A@1224|Proteobacteria,2VKDA@28216|Betaproteobacteria,1KMZH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
PYH2_k127_961317_5	395495.Lcho_2415	6.406e-149	476.0	COG3777@1|root,COG3777@2|Bacteria,1P96N@1224|Proteobacteria,2VIUS@28216|Betaproteobacteria,1KKUZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	N-terminal half of MaoC dehydratase	-	-	4.2.1.153,4.2.1.56	ko:K09709,ko:K18291	ko00660,ko00720,ko01120,ko01200,map00660,map00720,map01120,map01200	M00376	R02491,R09282	RC00730,RC02479	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydrat_N
PYH2_k127_961317_6	1276756.AUEX01000030_gene200	3.103e-88	305.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2VQ0V@28216|Betaproteobacteria,4AGUW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PYH2_k127_961317_0	1286631.X805_38400	2.155e-271	842.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,2VHKU@28216|Betaproteobacteria,1KJUJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
PYH2_k127_961317_7	595537.Varpa_3454	1.169e-68	237.0	2C1K4@1|root,30F52@2|Bacteria,1REDQ@1224|Proteobacteria,2VRSY@28216|Betaproteobacteria,4ADXR@80864|Comamonadaceae	28216|Betaproteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	ko:K07794	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctB
PYH2_k127_961317_3	296591.Bpro_2009	2.007e-166	529.0	COG3181@1|root,COG3181@2|Bacteria,1MXEX@1224|Proteobacteria,2VJTU@28216|Betaproteobacteria,4AAYT@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	ko:K07795	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctC
PYH2_k127_961317_8	426114.THI_1592	1.158e-37	157.0	2DP5N@1|root,330MP@2|Bacteria,1NEVU@1224|Proteobacteria,2VWCM@28216|Betaproteobacteria,1KMHS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_979851_10	497321.C664_04842	3.312e-12	67.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2VJB8@28216|Betaproteobacteria,2KUFW@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
PYH2_k127_979851_8	522306.CAP2UW1_3209	5.214e-24	109.0	2DP14@1|root,3303I@2|Bacteria,1N7JW@1224|Proteobacteria,2W98X@28216|Betaproteobacteria,1KR4Z@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_979851_7	522306.CAP2UW1_3208	6.417e-30	135.0	2CESE@1|root,32S0D@2|Bacteria,1RHTD@1224|Proteobacteria,2VSJ5@28216|Betaproteobacteria,1KQXW@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA,Gly-zipper_YMGG
PYH2_k127_979851_9	1077972.ARGLB_113_00300	5.524e-15	83.0	COG4319@1|root,COG4319@2|Bacteria,2IHRK@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_3
PYH2_k127_979851_5	296591.Bpro_1187	1.204e-72	251.0	COG2181@1|root,COG2181@2|Bacteria,1QQCT@1224|Proteobacteria,2VU6P@28216|Betaproteobacteria	28216|Betaproteobacteria	C	nitrate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PYH2_k127_979851_1	864051.BurJ1DRAFT_3315	6.84e-227	723.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,2VJGA@28216|Betaproteobacteria,1KN5P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Fe-S oxidoreductase	-	-	-	ko:K21834	-	-	-	-	ko00000	-	-	-	CCG,DUF3483,Fer4_8
PYH2_k127_979851_2	864051.BurJ1DRAFT_3346	6.141e-171	543.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,2VKGG@28216|Betaproteobacteria,1KNC0@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
PYH2_k127_979851_4	864051.BurJ1DRAFT_3347	4.018e-77	260.0	COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,2VS0Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	DsrE/DsrF/DrsH-like family	-	-	-	-	-	-	-	-	-	-	-	-	DrsE_2
PYH2_k127_979851_6	864051.BurJ1DRAFT_3348	3.888e-35	134.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
PYH2_k127_979851_0	395495.Lcho_3778	0.0	1017.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,2VJTS@28216|Betaproteobacteria,1KK3V@119065|unclassified Burkholderiales	28216|Betaproteobacteria	F	Belongs to the 5'-nucleotidase family	soxB	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C
PYH2_k127_979851_3	420662.Mpe_A2433	7.112e-80	269.0	COG2010@1|root,COG2010@2|Bacteria,1P1GY@1224|Proteobacteria,2VP4W@28216|Betaproteobacteria,1KMCY@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome c	soxX	-	-	ko:K17223	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
## 3964 queries scanned
## Total time (seconds): 47.48635411262512
## Rate: 83.48 q/s