## Mon Nov 11 21:04:31 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/R/REGS1_bin.1.fa -m mmseqs --itype genome -o REGS1_bin.1 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/REGS1_bin.1 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
REGS1_k127_1016058_3	1122963.AUHB01000003_gene4159	0.0001056	46.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2TV4H@28211|Alphaproteobacteria,36ZPK@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Biotin-lipoyl like	macA	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_1016058_2	1121479.AUBS01000047_gene797	8.131e-14	84.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2TV4H@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	macA	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_D23
REGS1_k127_1016058_0	926569.ANT_07920	2.154e-83	284.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_1016058_1	926569.ANT_07930	1.608e-21	96.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_1023695_0	1379698.RBG1_1C00001G0858	1.494e-54	203.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C
REGS1_k127_1023695_1	1499967.BAYZ01000118_gene3269	5.218e-07	58.0	COG5001@1|root,COG5001@2|Bacteria,2NP1A@2323|unclassified Bacteria	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4084,EAL,GGDEF,MASE3,PAS
REGS1_k127_1041368_5	1304874.JAFY01000002_gene574	1.602e-88	303.0	COG5598@1|root,COG5598@2|Bacteria,3TC8U@508458|Synergistetes	508458|Synergistetes	H	Trimethylamine methyltransferase (MTTB)	-	-	-	-	-	-	-	-	-	-	-	-	MTTB
REGS1_k127_1041368_2	1047013.AQSP01000134_gene1338	1.605e-113	383.0	COG5598@1|root,COG5598@2|Bacteria,2NQTC@2323|unclassified Bacteria	2|Bacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
REGS1_k127_1041368_3	926550.CLDAP_01290	2.547e-112	374.0	COG1473@1|root,COG1473@2|Bacteria,2G7D3@200795|Chloroflexi	200795|Chloroflexi	S	peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_1041368_7	1487923.DP73_21445	1.498e-83	286.0	COG1410@1|root,COG1410@2|Bacteria,1VRVS@1239|Firmicutes,25EJA@186801|Clostridia,267HQ@186807|Peptococcaceae	186801|Clostridia	E	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind
REGS1_k127_1041368_0	1121430.JMLG01000016_gene367	4.051e-177	576.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,260RG@186807|Peptococcaceae	186801|Clostridia	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
REGS1_k127_1041368_8	903818.KI912269_gene107	2.003e-68	244.0	COG0646@1|root,COG0646@2|Bacteria,3Y7SY@57723|Acidobacteria	57723|Acidobacteria	E	Homocysteine S-methyltransferase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	S-methyl_trans
REGS1_k127_1041368_4	926569.ANT_11580	6.399e-105	352.0	COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
REGS1_k127_1041368_9	1382356.JQMP01000004_gene363	2.422e-58	210.0	COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia	189775|Thermomicrobia	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_1041368_1	926569.ANT_11560	1.133e-123	412.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_1094157_3	926569.ANT_15730	0.0008731	44.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
REGS1_k127_1094157_2	555079.Toce_0227	1.625e-43	160.0	COG3829@1|root,COG3829@2|Bacteria,1VBSS@1239|Firmicutes	1239|Firmicutes	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1094157_0	926569.ANT_15720	6.525e-159	512.0	COG0535@1|root,COG0535@2|Bacteria,2G5XT@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
REGS1_k127_109553_0	909663.KI867150_gene476	4.01e-268	860.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,43789@68525|delta/epsilon subdivisions,2X2AW@28221|Deltaproteobacteria,2MS3Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
REGS1_k127_109553_1	383372.Rcas_2645	3.439e-196	650.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
REGS1_k127_109553_3	1173028.ANKO01000065_gene5643	4.357e-61	216.0	COG0288@1|root,COG0288@2|Bacteria,1G3RZ@1117|Cyanobacteria,1H9V9@1150|Oscillatoriales	1117|Cyanobacteria	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
REGS1_k127_109553_2	926550.CLDAP_34850	4.158e-102	338.0	COG0647@1|root,COG0647@2|Bacteria,2G60W@200795|Chloroflexi	200795|Chloroflexi	G	COGs COG0647 sugar phosphatase of the HAD superfamily	-	-	-	ko:K02566	-	-	-	-	ko00000	-	-	-	Hydrolase_6,Hydrolase_like
REGS1_k127_1178578_2	926569.ANT_18350	5.111e-24	106.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_1178578_1	926569.ANT_18350	3.766e-33	137.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_1178578_0	926569.ANT_18360	3.519e-138	446.0	COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi	200795|Chloroflexi	S	ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_1197205_14	357808.RoseRS_0609	8.016e-69	246.0	COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,375JB@32061|Chloroflexia	32061|Chloroflexia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
REGS1_k127_1197205_13	357808.RoseRS_0608	1.078e-70	247.0	COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,375FI@32061|Chloroflexia	32061|Chloroflexia	P	Ferric reductase like transmembrane component	-	-	-	-	-	-	-	-	-	-	-	-	Ferric_reduct
REGS1_k127_1197205_7	926569.ANT_21040	1.077e-147	482.0	COG0297@1|root,COG0297@2|Bacteria,2G60C@200795|Chloroflexi	200795|Chloroflexi	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
REGS1_k127_1197205_4	987059.RBXJA2T_07463	3.528e-166	536.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,2VJUV@28216|Betaproteobacteria,1KK55@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
REGS1_k127_1197205_18	926569.ANT_30840	2.928e-21	98.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Fer4_7,HTH_Crp_2,cNMP_binding
REGS1_k127_1197205_17	1200792.AKYF01000008_gene755	9.788e-30	126.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,26XRF@186822|Paenibacillaceae	91061|Bacilli	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_1197205_16	926550.CLDAP_23690	3.653e-39	150.0	COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi	200795|Chloroflexi	O	PFAM OsmC family protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
REGS1_k127_1197205_5	926569.ANT_12080	4.096e-161	522.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
REGS1_k127_1197205_6	926569.ANT_12100	2.84e-157	512.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,OapA,OapA_N,Peptidase_M23
REGS1_k127_1197205_9	926569.ANT_12110	2.779e-139	466.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	2.7.7.6	ko:K03046,ko:K03641,ko:K08642	ko00230,ko00240,ko01100,ko02024,ko03020,map00230,map00240,map01100,map02024,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko01002,ko02000,ko03021,ko03400	2.C.1.2	-	-	Glyco_hydro_18,LysM,OapA,PD40,Peptidase_M23
REGS1_k127_1197205_11	926569.ANT_02710	3.097e-79	276.0	COG1526@1|root,COG1526@2|Bacteria,2G74E@200795|Chloroflexi	200795|Chloroflexi	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
REGS1_k127_1197205_3	926569.ANT_11210	7.852e-178	571.0	COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,2G64T@200795|Chloroflexi	200795|Chloroflexi	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5,4.3.1.4	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R02302,R03189	RC00165,RC00221,RC00223,RC00688,RC00870	ko00000,ko00001,ko01000,ko03036,ko04147	-	-	-	FTCD,FTCD_C,FTCD_N
REGS1_k127_1197205_10	926569.ANT_11190	5.163e-104	339.0	COG0717@1|root,COG0717@2|Bacteria,2G7HJ@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
REGS1_k127_1197205_2	926569.ANT_07350	1.064e-181	586.0	COG2898@1|root,COG2898@2|Bacteria,2G6KJ@200795|Chloroflexi	200795|Chloroflexi	S	conserved protein (DUF2156)	-	-	2.3.2.3	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504	2.A.1.3.37	-	-	DUF2156,LPG_synthase_TM
REGS1_k127_1197205_8	926550.CLDAP_02910	1.745e-147	479.0	COG2270@1|root,COG2270@2|Bacteria,2G633@200795|Chloroflexi	200795|Chloroflexi	S	Vacuole effluxer Atg22 like	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
REGS1_k127_1197205_0	926569.ANT_09980	0.0	2035.0	COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
REGS1_k127_1197205_12	926569.ANT_09990	4.782e-71	241.0	COG0048@1|root,COG0048@2|Bacteria,2G6EX@200795|Chloroflexi	200795|Chloroflexi	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
REGS1_k127_1197205_15	926569.ANT_10000	2.196e-59	209.0	COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
REGS1_k127_1197205_1	926569.ANT_10010	8.484e-192	605.0	COG0480@1|root,COG0480@2|Bacteria,2G63B@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_120909_1	869210.Marky_1921	2.578e-27	115.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
REGS1_k127_120909_0	1047013.AQSP01000144_gene839	4.862e-34	149.0	COG1807@1|root,COG1807@2|Bacteria,2NRV3@2323|unclassified Bacteria	2|Bacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723,PMT_2
REGS1_k127_1216868_4	428126.CLOSPI_02359	6.923e-09	60.0	COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes,3VQ5U@526524|Erysipelotrichia	526524|Erysipelotrichia	GM	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
REGS1_k127_1216868_1	1267535.KB906767_gene2539	6.546e-81	287.0	COG0279@1|root,COG0279@2|Bacteria,3Y49P@57723|Acidobacteria,2JMTY@204432|Acidobacteriia	204432|Acidobacteriia	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
REGS1_k127_1216868_2	234267.Acid_0421	1.206e-58	221.0	COG0241@1|root,COG0241@2|Bacteria,3Y7VH@57723|Acidobacteria	57723|Acidobacteria	E	HAD-hyrolase-like	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_like
REGS1_k127_1216868_0	671143.DAMO_0942	3.233e-97	323.0	COG0176@1|root,COG0176@2|Bacteria,2NP61@2323|unclassified Bacteria	2|Bacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
REGS1_k127_1216868_3	1340493.JNIF01000003_gene2034	1.931e-12	72.0	COG2804@1|root,COG2804@2|Bacteria,3Y2IS@57723|Acidobacteria	57723|Acidobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_1223682_1	1267533.KB906740_gene367	1.061e-52	194.0	COG1629@1|root,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,TonB_dep_Rec
REGS1_k127_1223682_0	1267533.KB906736_gene852	7.627e-59	209.0	COG0634@1|root,COG0634@2|Bacteria,3Y7PS@57723|Acidobacteria,2JMQY@204432|Acidobacteriia	204432|Acidobacteriia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
REGS1_k127_1236952_3	589924.Ferp_1759	7.197e-29	123.0	COG1765@1|root,arCOG03686@2157|Archaea,2XYGU@28890|Euryarchaeota	28890|Euryarchaeota	O	redox protein, regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
REGS1_k127_1236952_1	589924.Ferp_1758	3.727e-98	331.0	COG0407@1|root,arCOG03323@2157|Archaea,2XV21@28890|Euryarchaeota	28890|Euryarchaeota	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	2.1.1.246,4.1.1.37	ko:K01599,ko:K14080	ko00680,ko00860,ko01100,ko01110,ko01120,ko01200,map00680,map00860,map01100,map01110,map01120,map01200	M00121,M00356	R03197,R04972,R09098,R10000	RC00035,RC00872,RC01144,RC02440	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
REGS1_k127_1236952_0	760568.Desku_0057	5.466e-238	762.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,260RG@186807|Peptococcaceae	186801|Clostridia	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
REGS1_k127_1236952_2	760568.Desku_0058	2.671e-76	261.0	COG1962@1|root,COG1962@2|Bacteria,1UYYD@1239|Firmicutes,24AC2@186801|Clostridia,26150@186807|Peptococcaceae	186801|Clostridia	H	Tetrahydromethanopterin S-methyltransferase MtrH subunit	-	-	2.1.1.86	ko:K00584	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00357,M00567	R04347	RC00035,RC00113,RC02892	ko00000,ko00001,ko00002,ko01000	-	-	-	MtrH
REGS1_k127_123757_1	926569.ANT_23330	2.824e-104	353.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
REGS1_k127_123757_2	926569.ANT_23310	6.153e-104	346.0	COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
REGS1_k127_123757_4	926569.ANT_23300	1.989e-40	154.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
REGS1_k127_123757_0	1128421.JAGA01000002_gene694	1.662e-107	356.0	COG1092@1|root,COG1092@2|Bacteria	2|Bacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
REGS1_k127_123757_5	1173264.KI913949_gene683	1.448e-05	57.0	28MCN@1|root,2ZAQR@2|Bacteria,1G1C5@1117|Cyanobacteria,1H8NJ@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_123757_3	378806.STAUR_7924	1.277e-75	267.0	COG1181@1|root,COG1181@2|Bacteria,1Q3H4@1224|Proteobacteria,4399M@68525|delta/epsilon subdivisions,2X4H1@28221|Deltaproteobacteria,2YZ01@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
REGS1_k127_1253318_3	278957.ABEA03000130_gene1695	5.539e-07	52.0	COG0564@1|root,COG0564@2|Bacteria,46ZAW@74201|Verrucomicrobia,3K7AJ@414999|Opitutae	414999|Opitutae	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
REGS1_k127_1253318_0	926569.ANT_22990	1.185e-171	548.0	COG4198@1|root,COG4198@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015,SusD-like,SusD-like_2
REGS1_k127_1253318_1	387631.Asulf_00760	1.792e-91	311.0	COG0111@1|root,arCOG01754@2157|Archaea,2XU9V@28890|Euryarchaeota,246MG@183980|Archaeoglobi	183980|Archaeoglobi	E	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
REGS1_k127_1253318_2	926569.ANT_30620	7.663e-86	290.0	COG1932@1|root,COG1932@2|Bacteria,2G7RM@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
REGS1_k127_1253935_1	589865.DaAHT2_0700	6.154e-61	229.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MPI2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
REGS1_k127_1253935_2	443143.GM18_4304	4.169e-31	138.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
REGS1_k127_1253935_0	1123023.JIAI01000002_gene5476	8.62e-85	287.0	COG0030@1|root,COG0030@2|Bacteria,2GIZ8@201174|Actinobacteria,4DYTH@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_1259567_5	330214.NIDE0829	2.706e-28	116.0	COG5459@1|root,COG5459@2|Bacteria,3J16W@40117|Nitrospirae	40117|Nitrospirae	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
REGS1_k127_1259567_4	330214.NIDE0832	2.862e-39	151.0	COG2453@1|root,COG2453@2|Bacteria	2|Bacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	DSPc
REGS1_k127_1259567_1	330214.NIDE0833	5.079e-110	362.0	COG0266@1|root,COG0266@2|Bacteria,3J17X@40117|Nitrospirae	40117|Nitrospirae	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
REGS1_k127_1259567_0	330214.NIDE0834	1.103e-238	740.0	COG0045@1|root,COG0045@2|Bacteria,3J185@40117|Nitrospirae	40117|Nitrospirae	H	ATP citrate lyase citrate-binding	-	-	2.3.3.8	ko:K15231	ko00020,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00720,map01100,map01110,map01120,map01130,map01200	M00173	R00352	RC00004,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Citrate_bind
REGS1_k127_1259567_2	330214.NIDE0835	9.958e-83	276.0	COG0074@1|root,COG0372@1|root,COG0074@2|Bacteria,COG0372@2|Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	-	-	2.3.3.8,6.2.1.5	ko:K01902,ko:K15230,ko:K15233	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00352,R00405,R01322,R02404	RC00004,RC00014,RC00067	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0306	Citrate_synt,CoA_binding,Ligase_CoA,Succ_CoA_lig
REGS1_k127_1267311_0	926569.ANT_25450	1.427e-163	519.0	COG2896@1|root,COG2896@2|Bacteria,2G5JT@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
REGS1_k127_1267311_1	1125863.JAFN01000001_gene2910	8.084e-19	95.0	COG1011@1|root,COG1011@2|Bacteria,1NIPN@1224|Proteobacteria	1224|Proteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
REGS1_k127_1270752_4	272123.Anacy_0958	7.712e-05	55.0	COG2755@1|root,COG2755@2|Bacteria,1FZYY@1117|Cyanobacteria,1HK2Z@1161|Nostocales	1117|Cyanobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1574
REGS1_k127_1270752_1	999541.bgla_2g16090	5.466e-68	248.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2VISD@28216|Betaproteobacteria,1K5Z8@119060|Burkholderiaceae	28216|Betaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	pacA	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
REGS1_k127_1270752_0	204669.Acid345_0734	2.053e-113	386.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
REGS1_k127_1270752_5	1171373.PACID_19450	8.505e-05	48.0	COG0236@1|root,COG0236@2|Bacteria,2H7G5@201174|Actinobacteria,4DW64@85009|Propionibacteriales	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1270752_3	536019.Mesop_2606	1.152e-15	85.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.7.8.20	ko:K01002,ko:K20534	ko01100,map01100	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	GT87,Glycos_transf_2
REGS1_k127_1270752_2	204669.Acid345_0416	4.062e-16	82.0	COG4447@1|root,COG4447@2|Bacteria,3Y4R8@57723|Acidobacteria,2JMPX@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1312209_0	1121405.dsmv_3003	0.0	1557.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_1312209_5	1173025.GEI7407_0476	5.635e-11	65.0	COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria,1H7CT@1150|Oscillatoriales	1117|Cyanobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
REGS1_k127_1312209_2	179408.Osc7112_5083	2.115e-150	477.0	COG3957@1|root,COG3957@2|Bacteria,1G0B2@1117|Cyanobacteria,1H7CT@1150|Oscillatoriales	1117|Cyanobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
REGS1_k127_1312209_3	1267534.KB906755_gene4240	4.749e-70	242.0	COG0406@1|root,COG0406@2|Bacteria,3Y4QW@57723|Acidobacteria,2JJB8@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
REGS1_k127_1312209_1	671143.DAMO_2785	1.788e-175	553.0	COG0115@1|root,COG0115@2|Bacteria,2NP1Q@2323|unclassified Bacteria	2|Bacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
REGS1_k127_1312209_4	269799.Gmet_0955	1.327e-30	126.0	COG0745@1|root,COG0745@2|Bacteria,1NER5@1224|Proteobacteria,42VHC@68525|delta/epsilon subdivisions,2WSGQ@28221|Deltaproteobacteria,43UMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_1320801_1	330214.NIDE4381	1.612e-86	291.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	MA20_24420	-	-	ko:K06889,ko:K07000	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,Hydrolase_4,UPF0227
REGS1_k127_1320801_0	330214.NIDE4382	1.444e-102	338.0	COG0400@1|root,COG0400@2|Bacteria,3J1DU@40117|Nitrospirae	40117|Nitrospirae	S	Alpha/beta hydrolase family	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
REGS1_k127_1320801_2	330214.NIDE4383	1.686e-36	148.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_13420_2	1267535.KB906767_gene1609	7.6e-62	224.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
REGS1_k127_13420_1	861299.J421_5887	3.259e-69	245.0	arCOG07533@1|root,2ZF5I@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4386
REGS1_k127_13420_4	234267.Acid_4150	3.5e-25	105.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
REGS1_k127_13420_0	639030.JHVA01000001_gene3035	2.503e-190	603.0	COG0841@1|root,COG0841@2|Bacteria,3Y2SK@57723|Acidobacteria,2JM25@204432|Acidobacteriia	204432|Acidobacteriia	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_1355717_9	926569.ANT_15960	1.147e-23	100.0	COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi	200795|Chloroflexi	F	PFAM metal-dependent phosphohydrolase, HD sub domain	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
REGS1_k127_1355717_7	926569.ANT_15970	3.298e-47	173.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_1355717_4	926569.ANT_15980	1.42e-68	245.0	28T1C@1|root,2ZFAN@2|Bacteria,2G9NB@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1355717_0	926569.ANT_15990	0.0	1107.0	COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi	200795|Chloroflexi	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
REGS1_k127_1355717_3	926569.ANT_16000	2.51e-118	390.0	COG0836@1|root,COG0836@2|Bacteria,2G5WW@200795|Chloroflexi	200795|Chloroflexi	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
REGS1_k127_1355717_2	926569.ANT_16010	8.57e-121	398.0	COG0758@1|root,COG0758@2|Bacteria,2G5UA@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA protecting protein DprA	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
REGS1_k127_1355717_6	926569.ANT_16020	4.668e-48	178.0	COG0806@1|root,COG0806@2|Bacteria,2G707@200795|Chloroflexi	200795|Chloroflexi	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
REGS1_k127_1355717_10	926569.ANT_16030	5.536e-21	96.0	COG1837@1|root,COG1837@2|Bacteria,2G7DU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
REGS1_k127_1355717_8	926569.ANT_16040	2.358e-37	143.0	COG0228@1|root,COG0228@2|Bacteria,2G7A3@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
REGS1_k127_1355717_1	926569.ANT_16050	5.358e-185	587.0	COG0541@1|root,COG0541@2|Bacteria,2G627@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
REGS1_k127_1355717_5	429009.Adeg_1695	1.508e-50	186.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,42FBT@68295|Thermoanaerobacterales	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
REGS1_k127_1379768_0	926569.ANT_20250	1.555e-99	334.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi	200795|Chloroflexi	M	Short-chain dehydrogenase reductase SDR	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_1379768_1	509190.Cseg_1870	9.722e-70	244.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,2U7DN@28211|Alphaproteobacteria,2KGAG@204458|Caulobacterales	204458|Caulobacterales	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
REGS1_k127_1379768_2	525904.Tter_0154	1.119e-29	123.0	COG0279@1|root,COG0279@2|Bacteria,2NR5H@2323|unclassified Bacteria	2|Bacteria	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
REGS1_k127_1389535_23	556261.HMPREF0240_03903	5.245e-13	71.0	COG0407@1|root,COG0407@2|Bacteria,1TSSK@1239|Firmicutes,24CHA@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
REGS1_k127_1389535_2	1499967.BAYZ01000190_gene3853	1.611e-152	488.0	COG0407@1|root,COG0407@2|Bacteria,2NPXG@2323|unclassified Bacteria	2|Bacteria	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
REGS1_k127_1389535_15	1499967.BAYZ01000080_gene956	1.067e-68	240.0	COG5012@1|root,COG5012@2|Bacteria,2NQTJ@2323|unclassified Bacteria	2|Bacteria	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
REGS1_k127_1389535_12	457424.BFAG_04162	2.788e-71	249.0	COG1180@1|root,COG1180@2|Bacteria,4NIUZ@976|Bacteroidetes,2FP2R@200643|Bacteroidia,4AM94@815|Bacteroidaceae	976|Bacteroidetes	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
REGS1_k127_1389535_1	180332.JTGN01000004_gene2630	1.024e-181	591.0	COG1882@1|root,COG1882@2|Bacteria	2|Bacteria	C	formate C-acetyltransferase activity	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Dyp_perox,Gly_radical,PFL-like
REGS1_k127_1389535_0	1128421.JAGA01000001_gene2416	7.498e-203	641.0	COG2160@1|root,COG2160@2|Bacteria	2|Bacteria	G	L-arabinose isomerase activity	araA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008733,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1922,iB21_1397.B21_00063,iBWG_1329.BWG_0058,iE2348C_1286.E2348C_0063,iECBD_1354.ECBD_3555,iECD_1391.ECD_00064,iECED1_1282.ECED1_0061,iECIAI1_1343.ECIAI1_0062,iECNA114_1301.ECNA114_0050,iECO103_1326.ECO103_0063,iECO26_1355.ECO26_0064,iECOK1_1307.ECOK1_0061,iECP_1309.ECP_0063,iECS88_1305.ECS88_0065,iECSE_1348.ECSE_0062,iECW_1372.ECW_m0060,iEKO11_1354.EKO11_3852,iEcE24377_1341.EcE24377A_0064,iEcHS_1320.EcHS_A0066,iEcSMS35_1347.EcSMS35_0064,iEcolC_1368.EcolC_3595,iLF82_1304.LF82_0105,iLJ478.TM0276,iNRG857_1313.NRG857_00320,iSBO_1134.SBO_0049,iSSON_1240.SSON_0068,iUMN146_1321.UM146_23095,iUTI89_1310.UTI89_C0067,iWFL_1372.ECW_m0060	Arabinose_Iso_C,Arabinose_Isome
REGS1_k127_1389535_21	484770.UFO1_3750	2.285e-21	94.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,4H3WT@909932|Negativicutes	909932|Negativicutes	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
REGS1_k127_1389535_22	1499967.BAYZ01000073_gene2030	2.053e-15	82.0	COG0006@1|root,COG0006@2|Bacteria	2|Bacteria	E	proline dipeptidase activity	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	Creatinase_N,Peptidase_M24
REGS1_k127_1389535_16	457421.CBFG_01578	3.226e-64	224.0	COG0432@1|root,COG0432@2|Bacteria	2|Bacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
REGS1_k127_1389535_14	457421.CBFG_01579	4.048e-69	247.0	COG0149@1|root,COG0149@2|Bacteria,1UZAR@1239|Firmicutes,248T5@186801|Clostridia	186801|Clostridia	G	triosephosphate isomerase	-	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
REGS1_k127_1389535_18	1370121.AUWS01000024_gene2537	5.595e-51	190.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, DeoR family	-	-	-	ko:K02081,ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
REGS1_k127_1389535_6	1499967.BAYZ01000032_gene1136	4.134e-117	392.0	COG2407@1|root,COG2407@2|Bacteria,2NR9P@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the conversion of L-arabinose to L-ribulose	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Isome,Fucose_iso_C
REGS1_k127_1389535_4	742733.HMPREF9469_04646	2.133e-134	445.0	COG1070@1|root,COG1070@2|Bacteria,1UICT@1239|Firmicutes,25EHS@186801|Clostridia,21YFF@1506553|Lachnoclostridium	186801|Clostridia	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
REGS1_k127_1389535_20	42256.RradSPS_3024	2.903e-33	139.0	COG1830@1|root,COG1830@2|Bacteria,2IB09@201174|Actinobacteria	201174|Actinobacteria	G	Aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
REGS1_k127_1389535_9	1367847.JCM7686_2805	7.158e-93	319.0	COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,2TS7Y@28211|Alphaproteobacteria,2PUGR@265|Paracoccus	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
REGS1_k127_1389535_7	686340.Metal_0215	3.827e-106	362.0	2DUCG@1|root,33PYM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1389535_8	485913.Krac_4682	6.291e-100	347.0	COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,TOBE_2
REGS1_k127_1389535_19	768704.Desmer_4506	3.971e-43	168.0	COG1177@1|root,COG1177@2|Bacteria,1V0UU@1239|Firmicutes,24AKA@186801|Clostridia,2631E@186807|Peptococcaceae	186801|Clostridia	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_1389535_13	357808.RoseRS_0792	1.796e-70	248.0	COG4132@1|root,COG4132@2|Bacteria,2G69Y@200795|Chloroflexi,376SV@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_1389535_5	1340493.JNIF01000003_gene2132	5.034e-128	426.0	COG0153@1|root,COG0153@2|Bacteria,3Y36C@57723|Acidobacteria	57723|Acidobacteria	G	GHMP kinases C terminal	-	-	-	-	-	-	-	-	-	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
REGS1_k127_1389535_17	1367847.JCM7686_2802	5.864e-57	207.0	COG1234@1|root,COG1234@2|Bacteria,1R64Z@1224|Proteobacteria,2TU6T@28211|Alphaproteobacteria,2PXZY@265|Paracoccus	28211|Alphaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
REGS1_k127_1389535_10	1367847.JCM7686_2803	1.097e-87	298.0	COG4132@1|root,COG4132@2|Bacteria,1NF20@1224|Proteobacteria,2U0S4@28211|Alphaproteobacteria,2PVG3@265|Paracoccus	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	-
REGS1_k127_1389535_11	1367847.JCM7686_2804	2.96e-79	274.0	COG1177@1|root,COG1177@2|Bacteria,1MV4A@1224|Proteobacteria,2TUA3@28211|Alphaproteobacteria,2PUMG@265|Paracoccus	1224|Proteobacteria	E	Binding-protein-dependent transport system inner membrane component	IV02_22295	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_1389535_3	1367847.JCM7686_2805	4.166e-147	474.0	COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,2TS7Y@28211|Alphaproteobacteria,2PUGR@265|Paracoccus	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
REGS1_k127_1392466_1	1128421.JAGA01000003_gene3696	3.463e-199	638.0	COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria	2|Bacteria	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
REGS1_k127_1392466_0	926569.ANT_13300	1.837e-201	639.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	200795|Chloroflexi	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9
REGS1_k127_1420664_5	264732.Moth_1992	1.38e-18	91.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1420664_3	926550.CLDAP_14450	6.783e-46	176.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
REGS1_k127_1420664_0	1128421.JAGA01000002_gene1308	3.904e-62	224.0	COG2197@1|root,COG2197@2|Bacteria,2NPMZ@2323|unclassified Bacteria	2|Bacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_1420664_2	525904.Tter_0301	3.61e-48	186.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
REGS1_k127_1420664_7	869210.Marky_1036	1.603e-14	79.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
REGS1_k127_1420664_1	1117108.PAALTS15_28541	1.867e-49	185.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,4HJYK@91061|Bacilli,26TVZ@186822|Paenibacillaceae	91061|Bacilli	Q	O-methyltransferase	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Ubie_methyltran
REGS1_k127_1420664_6	869210.Marky_1036	8.583e-17	81.0	COG3350@1|root,COG3350@2|Bacteria,1WN5Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	YHS domain	-	-	-	-	-	-	-	-	-	-	-	-	YHS
REGS1_k127_1420664_4	751944.HALDL1_00145	2.448e-29	122.0	COG2217@1|root,arCOG01576@2157|Archaea,2XT3T@28890|Euryarchaeota,23S6X@183963|Halobacteria	183963|Halobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
REGS1_k127_1454712_1	926569.ANT_25330	1.371e-64	231.0	COG1502@1|root,COG1502@2|Bacteria,2G8RC@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipase D Transphosphatidylase	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
REGS1_k127_1454712_2	326427.Cagg_3759	1.198e-31	132.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
REGS1_k127_1454712_3	326427.Cagg_3758	3.325e-18	97.0	COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia	32061|Chloroflexia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1454712_0	926569.ANT_13770	2.079e-67	232.0	COG0056@1|root,COG0056@2|Bacteria,2G5YQ@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
REGS1_k127_1462512_3	926550.CLDAP_21250	1.423e-64	224.0	COG4974@1|root,COG4974@2|Bacteria,2G7RJ@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
REGS1_k127_1462512_7	1200792.AKYF01000010_gene2058	1e-26	126.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4HC54@91061|Bacilli,2758S@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
REGS1_k127_1462512_10	1150599.MPHLEI_17332	3.72e-06	50.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,2379J@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,UPF0114
REGS1_k127_1462512_6	670487.Ocepr_0954	2.168e-27	128.0	2CP7W@1|root,32MRP@2|Bacteria,1WKBJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1462512_5	869210.Marky_1416	1.204e-29	135.0	2CP7W@1|root,32MRP@2|Bacteria,1WKBJ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1462512_9	278963.ATWD01000001_gene3739	3.988e-07	56.0	COG2963@1|root,COG2963@2|Bacteria,3Y86J@57723|Acidobacteria,2JN6K@204432|Acidobacteriia	204432|Acidobacteriia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
REGS1_k127_1462512_8	314225.ELI_14895	5.767e-08	57.0	COG2963@1|root,COG2963@2|Bacteria,1RGZ5@1224|Proteobacteria,2UAIS@28211|Alphaproteobacteria,2K5CA@204457|Sphingomonadales	204457|Sphingomonadales	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
REGS1_k127_1462512_2	1134413.ANNK01000133_gene2639	5.541e-81	276.0	COG4126@1|root,COG4126@2|Bacteria,1V0N4@1239|Firmicutes,4HP78@91061|Bacilli,1ZEWI@1386|Bacillus	91061|Bacilli	E	Hydantoin racemase	-	-	5.1.99.3	ko:K16841	ko00230,ko01120,map00230,map01120	-	R03925	RC01027	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
REGS1_k127_1462512_0	159450.NH14_25260	3.326e-239	751.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VITF@28216|Betaproteobacteria,1K3N4@119060|Burkholderiaceae	28216|Betaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
REGS1_k127_1462512_1	1535287.JP74_00955	7.266e-192	610.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,3N6U9@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14,6.4.1.6	ko:K01473,ko:K10855	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
REGS1_k127_1486593_2	1469613.JT55_05230	6.555e-113	381.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2TSTD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
REGS1_k127_1486593_1	926569.ANT_27900	9.745e-132	433.0	COG4603@1|root,COG4603@2|Bacteria,2G6MU@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
REGS1_k127_1486593_0	926569.ANT_27890	2.016e-213	674.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
REGS1_k127_1486593_6	1547437.LL06_20730	2.886e-103	348.0	COG1744@1|root,COG1744@2|Bacteria,1NGHH@1224|Proteobacteria,2TR36@28211|Alphaproteobacteria,43GX8@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	ABC-type transport system, periplasmic component surface lipoprotein	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
REGS1_k127_1486593_7	1254432.SCE1572_44715	1.987e-69	248.0	COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
REGS1_k127_1486593_4	926569.ANT_28060	6.318e-107	351.0	COG0336@1|root,COG0336@2|Bacteria,2G5MY@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
REGS1_k127_1486593_5	926569.ANT_00870	3.07e-104	353.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
REGS1_k127_1486593_3	926569.ANT_00860	1.955e-108	368.0	COG0457@1|root,COG0457@2|Bacteria,2G94P@200795|Chloroflexi	200795|Chloroflexi	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
REGS1_k127_148989_1	246197.MXAN_5824	4.957e-24	117.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_148989_0	1123248.KB893315_gene3000	2.053e-52	192.0	294EW@1|root,2ZRUR@2|Bacteria,4NPA3@976|Bacteroidetes,1ITCX@117747|Sphingobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF1569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1569
REGS1_k127_1550880_5	926569.ANT_19020	4.261e-22	95.0	COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi	200795|Chloroflexi	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
REGS1_k127_1550880_3	926569.ANT_10030	5.289e-54	192.0	COG0051@1|root,COG0051@2|Bacteria,2G6RB@200795|Chloroflexi	200795|Chloroflexi	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
REGS1_k127_1550880_1	926569.ANT_10040	1.838e-99	327.0	COG0087@1|root,COG0087@2|Bacteria,2G6DQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
REGS1_k127_1550880_2	926569.ANT_10050	3.126e-78	273.0	COG0088@1|root,COG0088@2|Bacteria,2G6K2@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
REGS1_k127_1550880_4	926569.ANT_10060	1.303e-29	120.0	COG0089@1|root,COG0089@2|Bacteria,2G73T@200795|Chloroflexi	200795|Chloroflexi	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
REGS1_k127_1550880_0	926569.ANT_10070	5.837e-122	394.0	COG0090@1|root,COG0090@2|Bacteria,2G65E@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
REGS1_k127_158152_2	483219.LILAB_22875	2.362e-05	56.0	COG3307@1|root,COG3307@2|Bacteria,1PX0E@1224|Proteobacteria,42VMH@68525|delta/epsilon subdivisions,2WS8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
REGS1_k127_158152_1	383372.Rcas_0468	8.766e-37	157.0	COG1807@1|root,COG1807@2|Bacteria,2G7Q8@200795|Chloroflexi,3782W@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_158152_0	435591.BDI_3232	2.886e-49	183.0	COG1216@1|root,COG1216@2|Bacteria,4NKAZ@976|Bacteroidetes,2FRDA@200643|Bacteroidia,22XTK@171551|Porphyromonadaceae	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_1587119_0	330214.NIDE0232	0.0	1151.0	COG3383@1|root,COG3383@2|Bacteria,3J0UR@40117|Nitrospirae	2|Bacteria	C	Molydopterin dinucleotide binding domain	hcnA	-	1.4.99.5,1.5.3.1	ko:K00302,ko:K10814	ko00260,ko00460,ko01100,ko01110,map00260,map00460,map01100,map01110	-	R00374,R00610,R05704	RC00060,RC00557,RC02808	ko00000,ko00001,ko01000,ko02042	-	-	-	Fer2_4
REGS1_k127_1601105_6	1382306.JNIM01000001_gene2947	1.405e-09	61.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_1601105_3	1128421.JAGA01000003_gene3534	3.102e-50	186.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.3,3.1.3.73,5.4.2.12	ko:K02226,ko:K15634,ko:K22305	ko00010,ko00260,ko00680,ko00860,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map00860,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00122	R00582,R01518,R04594,R11173	RC00017,RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
REGS1_k127_1601105_0	926569.ANT_00900	1.005e-203	643.0	COG2256@1|root,COG2256@2|Bacteria,2G5JC@200795|Chloroflexi	200795|Chloroflexi	L	PFAM AAA ATPase central domain protein	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
REGS1_k127_1601105_7	1184609.KILIM_069_00290	6.165e-06	53.0	COG1366@1|root,COG1366@2|Bacteria,2HPDK@201174|Actinobacteria,4F787@85018|Dermatophilaceae	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
REGS1_k127_1601105_5	1034769.KB910518_gene1906	1.114e-16	89.0	COG1011@1|root,COG1011@2|Bacteria,1TS3W@1239|Firmicutes,4HADE@91061|Bacilli,26QMB@186822|Paenibacillaceae	91061|Bacilli	S	haloacid dehalogenase	ysaA	-	3.1.3.5,3.8.1.2	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R05287	RC00017,RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_1601105_2	329726.AM1_4674	2.335e-56	208.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
REGS1_k127_1601105_1	926569.ANT_02010	4.745e-125	407.0	COG2057@1|root,COG2057@2|Bacteria,2G6MS@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
REGS1_k127_1601105_4	324602.Caur_2048	4.893e-32	134.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
REGS1_k127_1650849_3	401526.TcarDRAFT_1939	2.105e-21	101.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,4H595@909932|Negativicutes	909932|Negativicutes	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	-	-	-	-	-	-	-	-	-	-	ApbA,ApbA_C
REGS1_k127_1650849_1	477974.Daud_0100	6.305e-103	343.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,260CY@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
REGS1_k127_1650849_5	926569.ANT_23670	8.588e-07	53.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
REGS1_k127_1650849_2	926569.ANT_23140	2.473e-87	302.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_1650849_0	926550.CLDAP_35420	1.839e-170	546.0	COG1004@1|root,COG1004@2|Bacteria,2G62F@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
REGS1_k127_1650849_4	926569.ANT_27790	4.657e-10	60.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_165375_0	316274.Haur_2527	4.059e-30	122.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
REGS1_k127_165375_2	204669.Acid345_1799	1.288e-18	97.0	2DMUF@1|root,32TR1@2|Bacteria,3Y98H@57723|Acidobacteria,2JMXW@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_165375_1	996637.SGM_2559	5.028e-27	121.0	2E9JR@1|root,333SK@2|Bacteria,2GJVC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1666012_0	748449.Halha_1743	2.634e-209	659.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
REGS1_k127_1666012_1	926550.CLDAP_28230	5.865e-127	416.0	COG0006@1|root,COG0006@2|Bacteria,2G6N9@200795|Chloroflexi	200795|Chloroflexi	E	Metallopeptidase family M24	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	Peptidase_M24
REGS1_k127_1666012_2	28444.JODQ01000017_gene6503	1.147e-07	57.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,4EPJ4@85012|Streptosporangiales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14,1.1.1.264,1.1.1.303,1.1.1.4	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	M00014	R00875,R01896,R02855,R02946,R05684,R10504	RC00085,RC00089,RC00102,RC00205,RC00525	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_1679407_2	926569.ANT_15870	4.242e-153	505.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	PMT_2
REGS1_k127_1679407_6	926569.ANT_15880	2.819e-86	293.0	COG0500@1|root,COG2226@2|Bacteria,2G8SE@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_1679407_4	324602.Caur_3475	3.918e-133	434.0	COG0438@1|root,COG0438@2|Bacteria,2G84C@200795|Chloroflexi,375HH@32061|Chloroflexia	32061|Chloroflexia	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11
REGS1_k127_1679407_12	404380.Gbem_1627	6.353e-29	133.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	Cu-binding_MopE,Sulfatase
REGS1_k127_1679407_13	1552123.EP57_01470	9.142e-15	80.0	2C5NY@1|root,340BZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1679407_3	867845.KI911784_gene1969	3.22e-135	438.0	COG0451@1|root,COG0451@2|Bacteria,2G6ET@200795|Chloroflexi,375HU@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_1679407_10	926569.ANT_25890	2.431e-70	244.0	COG0705@1|root,COG0705@2|Bacteria,2G6J5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
REGS1_k127_1679407_11	926569.ANT_15900	1.389e-32	140.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
REGS1_k127_1679407_0	926569.ANT_15910	6.123e-305	944.0	COG0481@1|root,COG0481@2|Bacteria,2G5K2@200795|Chloroflexi	200795|Chloroflexi	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
REGS1_k127_1679407_8	926569.ANT_15920	1.677e-81	283.0	COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal RNA methyltransferase RrmJ FtsJ	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
REGS1_k127_1679407_5	926569.ANT_15930	1.129e-111	376.0	COG0382@1|root,COG0382@2|Bacteria,2G5WY@200795|Chloroflexi	200795|Chloroflexi	H	PFAM UbiA prenyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
REGS1_k127_1679407_7	926550.CLDAP_02720	1.064e-85	294.0	COG1577@1|root,COG1577@2|Bacteria,2G6DY@200795|Chloroflexi	200795|Chloroflexi	I	TIGRFAM mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
REGS1_k127_1679407_9	1382356.JQMP01000003_gene1688	3.972e-74	264.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27XXT@189775|Thermomicrobia	189775|Thermomicrobia	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
REGS1_k127_1679407_1	1396418.BATQ01000184_gene2632	1.761e-194	639.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
REGS1_k127_1681159_2	234267.Acid_2204	2.316e-28	120.0	COG0698@1|root,COG0698@2|Bacteria	2|Bacteria	G	galactose-6-phosphate isomerase activity	upp	-	2.4.2.9,5.3.1.6	ko:K00761,ko:K01808	ko00030,ko00051,ko00240,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00240,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R00966,R01056,R09030	RC00063,RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB,UPRTase
REGS1_k127_1681159_0	439292.Bsel_0177	3.746e-52	194.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,26NSA@186821|Sporolactobacillaceae	91061|Bacilli	K	UTRA	yvoA	-	-	ko:K03710,ko:K11922	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_1681159_1	485913.Krac_10537	3.757e-38	149.0	COG0274@1|root,COG0274@2|Bacteria,2G7HC@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
REGS1_k127_1681159_3	552396.HMPREF0863_02022	0.0005415	49.0	2E706@1|root,331J5@2|Bacteria,1VIFN@1239|Firmicutes,3VTV3@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_168497_0	926569.ANT_22850	0.0	1542.0	COG0060@1|root,COG0060@2|Bacteria,2G5SN@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
REGS1_k127_168497_4	1122194.AUHU01000007_gene315	1.653e-41	156.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1S5YX@1236|Gammaproteobacteria,467XF@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
REGS1_k127_168497_1	926569.ANT_18060	1.169e-288	913.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
REGS1_k127_168497_3	926569.ANT_18070	1.122e-47	179.0	COG0698@1|root,COG0698@2|Bacteria,2G6SM@200795|Chloroflexi	200795|Chloroflexi	G	Ribose/Galactose Isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
REGS1_k127_168497_2	926569.ANT_18080	1.074e-147	477.0	COG0021@1|root,COG0021@2|Bacteria,2G63Z@200795|Chloroflexi	200795|Chloroflexi	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
REGS1_k127_1701091_1	926569.ANT_15270	4.45e-192	617.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi	200795|Chloroflexi	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
REGS1_k127_1701091_13	316274.Haur_0363	7.382e-45	174.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,3776W@32061|Chloroflexia	32061|Chloroflexia	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
REGS1_k127_1701091_0	926569.ANT_15250	1.548e-206	656.0	COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Dak phosphatase	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
REGS1_k127_1701091_17	926569.ANT_15240	2.347e-35	138.0	COG1302@1|root,COG1302@2|Bacteria,2G76I@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
REGS1_k127_1701091_21	926569.ANT_15230	9.872e-17	84.0	COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi	200795|Chloroflexi	J	ribosomal protein L28	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
REGS1_k127_1701091_20	309807.SRU_0007	1.179e-19	91.0	COG0036@1|root,COG0036@2|Bacteria,4NDXB@976|Bacteroidetes,1FJ3C@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
REGS1_k127_1701091_14	378806.STAUR_6856	9.17e-44	164.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2YURC@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
REGS1_k127_1701091_5	926569.ANT_15210	7.669e-98	332.0	COG0515@1|root,COG0515@2|Bacteria,2G67H@200795|Chloroflexi	200795|Chloroflexi	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
REGS1_k127_1701091_16	926550.CLDAP_06200	1.635e-41	166.0	COG1597@1|root,COG1597@2|Bacteria,2G70R@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
REGS1_k127_1701091_4	926569.ANT_15200	1.364e-114	382.0	COG0387@1|root,COG0387@2|Bacteria,2G6GE@200795|Chloroflexi	200795|Chloroflexi	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
REGS1_k127_1701091_19	926569.ANT_15190	6.553e-29	123.0	2DTJR@1|root,33KPB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1701091_15	926569.ANT_15180	9.487e-42	159.0	COG3536@1|root,COG3536@2|Bacteria,2G7H1@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
REGS1_k127_1701091_8	926569.ANT_04450	1.031e-63	223.0	COG2078@1|root,COG2078@2|Bacteria	2|Bacteria	S	ferrous iron binding	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
REGS1_k127_1701091_18	926569.ANT_04460	2.491e-35	140.0	COG1853@1|root,COG1853@2|Bacteria,2G6XG@200795|Chloroflexi	200795|Chloroflexi	S	PFAM flavin reductase domain protein, FMN-binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
REGS1_k127_1701091_6	926569.ANT_30110	1.911e-70	247.0	COG0860@1|root,COG0860@2|Bacteria,2G7IE@200795|Chloroflexi	200795|Chloroflexi	M	PFAM cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
REGS1_k127_1701091_7	926569.ANT_30120	7.578e-69	249.0	COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi	200795|Chloroflexi	M	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_1701091_9	926569.ANT_30130	1.562e-63	235.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,YkuD
REGS1_k127_1701091_12	926569.ANT_30300	1.494e-53	191.0	2FH2K@1|root,348XD@2|Bacteria,2G93E@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1701091_2	926569.ANT_22760	2.25e-135	443.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	ko:K02532	-	-	-	-	ko00000,ko02000	2.A.1.5	-	-	MFS_1
REGS1_k127_1701091_11	945713.IALB_0056	1.288e-56	208.0	COG1028@1|root,COG1028@2|Bacteria	945713.IALB_0056|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1701091_3	765420.OSCT_1132	1.828e-123	402.0	COG2141@1|root,COG2141@2|Bacteria,2GB4X@200795|Chloroflexi,3779M@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
REGS1_k127_1701091_10	1434325.AZQN01000001_gene483	2.617e-57	207.0	COG5587@1|root,COG5587@2|Bacteria,4NNS3@976|Bacteroidetes,47J8W@768503|Cytophagia	976|Bacteroidetes	S	TIGRFAM TIGR02453 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
REGS1_k127_1701091_22	1242864.D187_001078	1.789e-07	52.0	COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,4343X@68525|delta/epsilon subdivisions,2X531@28221|Deltaproteobacteria,2Z01F@29|Myxococcales	28221|Deltaproteobacteria	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
REGS1_k127_1729987_2	517418.Ctha_2147	1.445e-32	141.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
REGS1_k127_1729987_0	1479238.JQMZ01000001_gene1911	4.69e-280	877.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1MZIG@1224|Proteobacteria,2UB61@28211|Alphaproteobacteria,43YUF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_1729987_1	1131269.AQVV01000034_gene2266	2.128e-86	290.0	COG0107@1|root,COG0107@2|Bacteria	2|Bacteria	E	imidazoleglycerol-phosphate synthase activity	hisF2	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
REGS1_k127_173157_3	909663.KI867149_gene3212	0.0002154	53.0	COG3103@1|root,COG3103@2|Bacteria,1R90G@1224|Proteobacteria,42YW1@68525|delta/epsilon subdivisions,2WTI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
REGS1_k127_173157_0	765420.OSCT_0159	2.715e-52	192.0	COG0637@1|root,COG0637@2|Bacteria,2G6ZZ@200795|Chloroflexi,377EF@32061|Chloroflexia	32061|Chloroflexia	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_173157_1	1124780.ANNU01000036_gene60	6.225e-49	193.0	COG4745@1|root,COG4745@2|Bacteria,4P4EE@976|Bacteroidetes	976|Bacteroidetes	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_173157_2	525904.Tter_0583	1.887e-32	136.0	2AZDP@1|root,31RMA@2|Bacteria,2NRKB@2323|unclassified Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
REGS1_k127_178448_2	1168034.FH5T_14775	1.551e-12	72.0	2EFWM@1|root,339NX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_178448_3	203119.Cthe_0073	1.805e-11	73.0	COG4758@1|root,COG4758@2|Bacteria,1UITP@1239|Firmicutes,24NAQ@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
REGS1_k127_178448_4	1286171.EAL2_c08220	4.294e-05	54.0	COG4758@1|root,COG4758@2|Bacteria,1UITP@1239|Firmicutes,24NAQ@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2154,Toast_rack_N
REGS1_k127_178448_1	485913.Krac_4117	7.663e-16	79.0	2DNVA@1|root,32ZBE@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_178448_0	1122927.KB895414_gene5084	1.744e-26	114.0	COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	GerE
REGS1_k127_1786051_0	1173025.GEI7407_3637	5.016e-53	189.0	COG1047@1|root,COG1047@2|Bacteria,1G5R4@1117|Cyanobacteria,1HBDB@1150|Oscillatoriales	1117|Cyanobacteria	O	PFAM FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
REGS1_k127_1786051_2	1306990.BARG01000044_gene5177	8.696e-05	53.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,2GJQI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_29,HTH_32
REGS1_k127_1786051_1	68219.JNXI01000003_gene4467	4.823e-48	183.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
REGS1_k127_1799463_1	926569.ANT_13070	3.021e-58	209.0	COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi	200795|Chloroflexi	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
REGS1_k127_1799463_2	443143.GM18_3157	1.135e-18	94.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_1799463_0	1121430.JMLG01000004_gene880	2.766e-291	905.0	COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24DPN@186801|Clostridia	186801|Clostridia	I	TIGRFAM Acetoacetyl-CoA synthase	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
REGS1_k127_1811875_3	1200792.AKYF01000010_gene2268	2.132e-25	112.0	COG1510@1|root,COG1510@2|Bacteria,1W1SP@1239|Firmicutes,4I07X@91061|Bacilli,26YW9@186822|Paenibacillaceae	91061|Bacilli	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11
REGS1_k127_1811875_0	765420.OSCT_2137	2.411e-111	372.0	COG4591@1|root,COG4591@2|Bacteria,2G85M@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
REGS1_k127_1811875_1	765420.OSCT_2138	1.555e-94	325.0	COG4591@1|root,COG4591@2|Bacteria,2G7ZF@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
REGS1_k127_1811875_2	765420.OSCT_2139	2.437e-63	220.0	COG1136@1|root,COG1136@2|Bacteria,2G7XA@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_1813942_2	247490.KSU1_C0653	1.251e-17	85.0	COG3237@1|root,COG3237@2|Bacteria,2J0JU@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
REGS1_k127_1813942_3	1128421.JAGA01000002_gene949	3.088e-17	83.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
REGS1_k127_1813942_1	479434.Sthe_2550	2.614e-18	91.0	COG0762@1|root,COG0762@2|Bacteria,2G9JK@200795|Chloroflexi,27ZAJ@189775|Thermomicrobia	189775|Thermomicrobia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1813942_4	289376.THEYE_A0128	8.332e-06	52.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
REGS1_k127_1813942_6	1246626.BleG1_3504	0.00085	45.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1813942_5	485913.Krac_7080	0.0001545	47.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,LUD_dom,SnoaL_3,SnoaL_4
REGS1_k127_1813942_0	479431.Namu_2437	1.7e-20	103.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4ETWR@85013|Frankiales	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_1820856_0	1380391.JIAS01000004_gene2960	1.449e-140	464.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,2JP86@204441|Rhodospirillales	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_1820856_1	1380391.JIAS01000004_gene2960	5.136e-131	436.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,2JP86@204441|Rhodospirillales	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_1820856_2	376686.Fjoh_2094	6.005e-37	143.0	COG0161@1|root,COG0161@2|Bacteria,4PMIJ@976|Bacteroidetes,1I86I@117743|Flavobacteriia,2NW82@237|Flavobacterium	976|Bacteroidetes	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
REGS1_k127_1825512_2	307480.IW16_13640	5.145e-14	80.0	COG0671@1|root,COG0671@2|Bacteria,4NI23@976|Bacteroidetes,1HYR2@117743|Flavobacteriia,3ZQMN@59732|Chryseobacterium	976|Bacteroidetes	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
REGS1_k127_1825512_4	1121929.KB898662_gene499	1.347e-06	58.0	2950P@1|root,2ZYQG@2|Bacteria,1V5HG@1239|Firmicutes,4HI30@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1825512_0	926569.ANT_26690	1.409e-48	177.0	COG1720@1|root,COG1720@2|Bacteria,2G799@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
REGS1_k127_1825512_3	357808.RoseRS_3519	9.225e-11	67.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,3776W@32061|Chloroflexia	32061|Chloroflexia	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
REGS1_k127_188731_5	926569.ANT_06480	8.645e-24	104.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_188731_4	272558.10176004	2.619e-27	122.0	COG0457@1|root,COG0457@2|Bacteria,1U9ZE@1239|Firmicutes,4IK7A@91061|Bacilli,1ZFKG@1386|Bacillus	91061|Bacilli	S	Sulfotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_1
REGS1_k127_188731_2	926569.ANT_06470	7.152e-130	422.0	COG2089@1|root,COG2089@2|Bacteria,2G8IV@200795|Chloroflexi	200795|Chloroflexi	M	NeuB family	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB
REGS1_k127_188731_0	926569.ANT_06460	2.923e-154	497.0	COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria	2|Bacteria	S	3-deoxy-manno-octulosonate-8-phosphatase activity	neuA	-	2.7.7.43,3.1.3.45	ko:K00983,ko:K03270	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
REGS1_k127_188731_3	926569.ANT_06450	2.211e-107	354.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
REGS1_k127_188731_6	1353531.AZNX01000012_gene3947	3.015e-19	102.0	2C1UQ@1|root,33VUD@2|Bacteria,1RM45@1224|Proteobacteria,2UBKR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_188731_1	326427.Cagg_1550	6.433e-133	428.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi,376A2@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
REGS1_k127_1897792_5	158500.BV97_02752	2.289e-28	123.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,2TTNG@28211|Alphaproteobacteria,2K8S6@204457|Sphingomonadales	204457|Sphingomonadales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_1897792_0	411489.CLOL250_02945	1.093e-73	258.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia,36EKX@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
REGS1_k127_1897792_4	411467.BACCAP_01544	1.258e-28	117.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,269AT@186813|unclassified Clostridiales	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
REGS1_k127_1897792_6	926569.ANT_07150	1.336e-22	100.0	COG4576@1|root,COG4576@2|Bacteria	2|Bacteria	CQ	ethanolamine utilization protein EutN carboxysome structural protein Ccml	ccmL	-	-	ko:K04028,ko:K08697	-	-	-	-	ko00000	-	-	-	EutN_CcmL
REGS1_k127_1897792_1	553973.CLOHYLEM_04358	7.097e-59	211.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
REGS1_k127_1897792_3	526218.Sterm_1038	8.736e-29	120.0	COG4577@1|root,COG4577@2|Bacteria,37AEM@32066|Fusobacteria	32066|Fusobacteria	CQ	PFAM microcompartments protein	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
REGS1_k127_1897792_2	1111728.ATYS01000007_gene1123	3.003e-41	164.0	COG0269@1|root,COG0269@2|Bacteria,1QWE4@1224|Proteobacteria,1RPV5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization	ulaD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0019852,GO:0019854,GO:0033982,GO:0042365,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046872,GO:0051186,GO:0051187,GO:0071704,GO:1901575	4.1.1.85	ko:K03078	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R07125	RC01721	ko00000,ko00001,ko00002,ko01000	-	-	iAF1260.b4196,iAPECO1_1312.APECO1_2196,iBWG_1329.BWG_3908,iE2348C_1286.E2348C_4519,iECDH10B_1368.ECDH10B_4391,iECDH1ME8569_1439.ECDH1ME8569_4053,iECED1_1282.ECED1_4983,iECIAI1_1343.ECIAI1_4429,iECNA114_1301.ECNA114_4412,iECOK1_1307.ECOK1_4710,iECP_1309.ECP_4441,iECS88_1305.ECS88_4782,iECSE_1348.ECSE_4494,iECSF_1327.ECSF_4082,iEcDH1_1363.EcDH1_3797,iJO1366.b4196,iJR904.b4196,iLF82_1304.LF82_2375,iNRG857_1313.NRG857_21325,iUMN146_1321.UM146_21220,iY75_1357.Y75_RS21850	OMPdecase
REGS1_k127_191853_16	1123487.KB892834_gene2720	2.484e-79	273.0	COG1122@1|root,COG1122@2|Bacteria,1QWP9@1224|Proteobacteria	1224|Proteobacteria	P	Pfam ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
REGS1_k127_191853_1	926569.ANT_28140	2.43e-213	667.0	COG0192@1|root,COG0192@2|Bacteria,2G5X0@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
REGS1_k127_191853_10	926569.ANT_19820	4.209e-111	375.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
REGS1_k127_191853_17	1230341.MJ3_08801	1.532e-62	227.0	COG0863@1|root,COG0863@2|Bacteria,1VC9K@1239|Firmicutes,4HSVW@91061|Bacilli	91061|Bacilli	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
REGS1_k127_191853_22	926569.ANT_28920	8.496e-35	143.0	28XMW@1|root,2ZJIW@2|Bacteria,2G9GS@200795|Chloroflexi	926569.ANT_28920|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_191853_9	926550.CLDAP_24920	1.086e-118	391.0	COG0451@1|root,COG0451@2|Bacteria,2G8B1@200795|Chloroflexi	200795|Chloroflexi	GM	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_191853_18	926569.ANT_28020	2.501e-52	196.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_4
REGS1_k127_191853_21	1293054.HSACCH_02053	7.249e-36	140.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3WBSP@53433|Halanaerobiales	186801|Clostridia	FG	Histidine triad (HIT) protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
REGS1_k127_191853_15	926569.ANT_12120	3.065e-81	285.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1
REGS1_k127_191853_12	926569.ANT_12120	3.221e-93	321.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Cadherin,HemolysinCabind,Peptidase_M10_C,Polysacc_deac_1
REGS1_k127_191853_2	926569.ANT_12130	3.583e-196	616.0	COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi	200795|Chloroflexi	I	Myo-inositol-1-phosphate synthase, GAPDH domain protein	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
REGS1_k127_191853_14	926569.ANT_16140	2.489e-82	284.0	COG0524@1|root,COG0524@2|Bacteria,2G9QW@200795|Chloroflexi	200795|Chloroflexi	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
REGS1_k127_191853_13	867845.KI911784_gene1475	1.797e-91	315.0	COG0624@1|root,COG0624@2|Bacteria,2G63E@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
REGS1_k127_191853_3	926569.ANT_23640	4.113e-182	586.0	COG2114@1|root,COG2203@1|root,COG5002@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,2G6X8@200795|Chloroflexi	200795|Chloroflexi	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF_2,GAF_3,Guanylate_cyc,PAS
REGS1_k127_191853_8	926569.ANT_23650	6.487e-119	411.0	COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
REGS1_k127_191853_4	926569.ANT_22580	2.257e-181	593.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria,2G8F8@200795|Chloroflexi	200795|Chloroflexi	KLTU	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Pkinase
REGS1_k127_191853_7	926569.ANT_25070	1.597e-121	398.0	COG1420@1|root,COG1420@2|Bacteria,2G6AQ@200795|Chloroflexi	200795|Chloroflexi	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
REGS1_k127_191853_20	926569.ANT_25060	2.844e-38	151.0	COG0576@1|root,COG0576@2|Bacteria,2G77I@200795|Chloroflexi	200795|Chloroflexi	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
REGS1_k127_191853_0	926569.ANT_25050	1.509e-315	977.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
REGS1_k127_191853_6	867845.KI911784_gene1691	3.485e-124	407.0	COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi,374VC@32061|Chloroflexia	32061|Chloroflexia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
REGS1_k127_191853_5	926569.ANT_17710	1.986e-130	423.0	COG1216@1|root,COG1216@2|Bacteria,2G961@200795|Chloroflexi	200795|Chloroflexi	H	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_191853_11	926569.ANT_27790	1.664e-109	361.0	COG0375@1|root,COG0500@1|root,COG0375@2|Bacteria,COG2226@2|Bacteria,2G8EN@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_1941425_8	926569.ANT_14350	5.79e-35	138.0	COG1610@1|root,COG1610@2|Bacteria,2G7B8@200795|Chloroflexi	200795|Chloroflexi	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
REGS1_k127_1941425_0	926569.ANT_14340	1.909e-193	625.0	COG1480@1|root,COG1480@2|Bacteria,2G5WC@200795|Chloroflexi	200795|Chloroflexi	S	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
REGS1_k127_1941425_9	926569.ANT_14330	1.094e-27	119.0	COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi	200795|Chloroflexi	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
REGS1_k127_1941425_7	926569.ANT_14320	1.385e-41	156.0	COG0818@1|root,COG0818@2|Bacteria,2G75I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
REGS1_k127_1941425_2	926569.ANT_14310	5.258e-114	375.0	COG0648@1|root,COG0648@2|Bacteria	2|Bacteria	L	deoxyribonuclease IV (phage-T4-induced) activity	-	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
REGS1_k127_1941425_10	1384049.CD29_07285	6.97e-06	56.0	2A6RZ@1|root,30VK4@2|Bacteria,1V5GS@1239|Firmicutes,4HHIA@91061|Bacilli,3J005@400634|Lysinibacillus	91061|Bacilli	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
REGS1_k127_1941425_3	926569.ANT_12930	6.303e-78	273.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
REGS1_k127_1941425_4	290317.Cpha266_1159	2.804e-61	218.0	COG2738@1|root,COG2738@2|Bacteria,1FEE1@1090|Chlorobi	1090|Chlorobi	S	PFAM peptidase, membrane zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
REGS1_k127_1941425_1	926569.ANT_12940	2.299e-149	484.0	COG0793@1|root,COG0793@2|Bacteria,2G6HR@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
REGS1_k127_1941425_5	926569.ANT_12960	1.006e-46	178.0	COG1011@1|root,COG1011@2|Bacteria,2G979@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
REGS1_k127_1941425_6	926569.ANT_12970	1.191e-43	164.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
REGS1_k127_1963048_0	926569.ANT_18700	2.372e-99	349.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
REGS1_k127_1963048_1	926569.ANT_22870	6.876e-20	90.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
REGS1_k127_196904_4	649638.Trad_2226	4.689e-25	114.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	lpqG	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
REGS1_k127_196904_1	926569.ANT_30470	1.361e-66	242.0	COG1630@1|root,COG1630@2|Bacteria,2G68Z@200795|Chloroflexi	200795|Chloroflexi	S	NurA	-	-	-	-	-	-	-	-	-	-	-	-	NurA
REGS1_k127_197748_0	926550.CLDAP_23290	2.2e-85	292.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi	200795|Chloroflexi	V	ABC transporter, transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_1981055_9	926569.ANT_27550	8.313e-16	82.0	COG5032@1|root,COG5032@2|Bacteria,2G6FZ@200795|Chloroflexi	200795|Chloroflexi	BDLTU	phosphatidylinositol kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	PI3_PI4_kinase
REGS1_k127_1981055_5	926569.ANT_04570	3.186e-63	222.0	298YA@1|root,2ZW25@2|Bacteria,2G6UQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
REGS1_k127_1981055_0	357808.RoseRS_0214	1.646e-252	789.0	COG1884@1|root,COG1884@2|Bacteria,2G62T@200795|Chloroflexi,374XE@32061|Chloroflexia	32061|Chloroflexia	I	TIGRFAM methylmalonyl-CoA mutase, large subunit	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
REGS1_k127_1981055_4	926569.ANT_05010	1.661e-128	419.0	COG1234@1|root,COG1234@2|Bacteria,2G6YW@200795|Chloroflexi	200795|Chloroflexi	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
REGS1_k127_1981055_1	926569.ANT_12840	1.27e-226	725.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
REGS1_k127_1981055_3	926569.ANT_12730	1.708e-169	545.0	COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
REGS1_k127_1981055_7	604331.AUHY01000005_gene808	4.179e-41	156.0	COG0589@1|root,COG0589@2|Bacteria,1WJW6@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Universal stress protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_1981055_6	926569.ANT_29910	4.484e-48	184.0	COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi	200795|Chloroflexi	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,NTPase_1
REGS1_k127_1981055_2	926569.ANT_29620	1.567e-169	539.0	COG1180@1|root,COG1180@2|Bacteria,2G6B2@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_1981055_8	1123288.SOV_4c04230	3.232e-40	158.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_1996602_4	1123247.AUIJ01000026_gene632	5.38e-40	154.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Belongs to the GcvT family	sardh	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
REGS1_k127_1996602_0	1298880.AUEV01000002_gene1744	2.506e-76	267.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria	201174|Actinobacteria	M	Choline ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH,Choline_kinase
REGS1_k127_1996602_3	309801.trd_1316	5.145e-45	184.0	COG0531@1|root,COG0531@2|Bacteria,2G76Z@200795|Chloroflexi	200795|Chloroflexi	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_1996602_1	338963.Pcar_0940	2.38e-56	206.0	COG1349@1|root,COG1349@2|Bacteria,1MXW2@1224|Proteobacteria,42VAF@68525|delta/epsilon subdivisions,2WRBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	DeoR C terminal sensor domain	-	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
REGS1_k127_1996602_2	309801.trd_1320	6.912e-47	179.0	arCOG06048@1|root,31EJQ@2|Bacteria,2G6TM@200795|Chloroflexi,27Z2Z@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1996602_6	1454004.AW11_01670	1.83e-14	83.0	COG0604@1|root,COG2905@1|root,COG0604@2|Bacteria,COG2905@2|Bacteria,1MXIK@1224|Proteobacteria,2W1P8@28216|Betaproteobacteria	28216|Betaproteobacteria	CT	Domain in cystathionine beta-synthase and other proteins.	-	-	1.3.1.85	ko:K14446	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09291	RC02481	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N,CBS
REGS1_k127_1996602_5	1402135.SUH3_11060	3.053e-28	115.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,1MUXJ@1224|Proteobacteria,2TRGS@28211|Alphaproteobacteria,3ZVHC@60136|Sulfitobacter	28211|Alphaproteobacteria	E	Belongs to the GcvT family	sardh	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
REGS1_k127_1997990_0	926569.ANT_07480	7.843e-63	229.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
REGS1_k127_1997990_1	525904.Tter_0403	6.912e-60	220.0	COG0600@1|root,COG0600@2|Bacteria,2NR30@2323|unclassified Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
REGS1_k127_2004754_1	215803.DB30_8568	4.029e-55	201.0	COG0702@1|root,COG0702@2|Bacteria,1N12V@1224|Proteobacteria,4398G@68525|delta/epsilon subdivisions,2X4FP@28221|Deltaproteobacteria,2YYXG@29|Myxococcales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
REGS1_k127_2004754_0	316274.Haur_1815	1.045e-191	625.0	COG1716@1|root,COG1716@2|Bacteria,2G8A1@200795|Chloroflexi,377ZW@32061|Chloroflexia	32061|Chloroflexia	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
REGS1_k127_2010732_1	1304284.L21TH_1525	4.461e-34	139.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N,RCC1_2
REGS1_k127_2010732_0	324602.Caur_2783	9.952e-80	276.0	COG0601@1|root,COG0601@2|Bacteria,2G662@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_2010732_2	1122947.FR7_3894	1.027e-20	102.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,4H2KV@909932|Negativicutes	909932|Negativicutes	E	ABC transporter substrate-binding protein	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_2063003_1	130081.XP_005709258.1	5.678e-22	98.0	COG1804@1|root,KOG3957@2759|Eukaryota	2759|Eukaryota	C	alpha-methylacyl-CoA racemase activity	SUGCT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008410,GO:0016740,GO:0016782,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0047369	2.8.3.13	ko:K18703	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
REGS1_k127_2063003_3	525903.Taci_1498	1.803e-10	62.0	COG3311@1|root,COG3311@2|Bacteria,3TCF2@508458|Synergistetes	508458|Synergistetes	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
REGS1_k127_2063003_0	350688.Clos_1827	2.492e-33	139.0	COG4974@1|root,COG4974@2|Bacteria,1UTX8@1239|Firmicutes,24DFG@186801|Clostridia,36E3B@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
REGS1_k127_2063003_2	511051.CSE_07130	3.003e-18	88.0	2ATRB@1|root,31JA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2063098_3	130081.XP_005709258.1	5.678e-22	98.0	COG1804@1|root,KOG3957@2759|Eukaryota	2759|Eukaryota	C	alpha-methylacyl-CoA racemase activity	SUGCT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0008410,GO:0016740,GO:0016782,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0047369	2.8.3.13	ko:K18703	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
REGS1_k127_2063098_8	525903.Taci_1498	2.017e-07	53.0	COG3311@1|root,COG3311@2|Bacteria,3TCF2@508458|Synergistetes	508458|Synergistetes	L	TIGRFAM DNA binding domain protein, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
REGS1_k127_2063098_4	350688.Clos_1827	2.118e-17	87.0	COG4974@1|root,COG4974@2|Bacteria,1UTX8@1239|Firmicutes,24DFG@186801|Clostridia,36E3B@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
REGS1_k127_2063098_9	161156.JQKW01000007_gene635	1.192e-05	52.0	COG4974@1|root,COG4974@2|Bacteria,2GGT8@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_2063098_6	448385.sce7791	5.467e-15	80.0	COG1846@1|root,COG1846@2|Bacteria,1Q1FN@1224|Proteobacteria,43161@68525|delta/epsilon subdivisions,2WX0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
REGS1_k127_2063098_1	243164.DET1179	4.732e-253	803.0	COG1132@1|root,COG1132@2|Bacteria,2G5RC@200795|Chloroflexi,34D3X@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_2063098_0	1121342.AUCO01000008_gene142	7.811e-291	903.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,36E4P@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_2063098_5	443254.Marpi_1685	5.216e-16	78.0	2ATRB@1|root,31JA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2063098_7	511051.CSE_07130	6.125e-10	60.0	2ATRB@1|root,31JA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2063098_10	443254.Marpi_1685	0.0008007	44.0	2ATRB@1|root,31JA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2063098_2	926569.ANT_05660	4.222e-26	112.0	COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi	200795|Chloroflexi	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
REGS1_k127_2064252_1	926569.ANT_16300	4.698e-103	342.0	COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
REGS1_k127_2064252_3	926569.ANT_13760	4.576e-58	207.0	COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
REGS1_k127_2064252_4	926569.ANT_13740	1.797e-55	198.0	COG0817@1|root,COG0817@2|Bacteria,2G6MA@200795|Chloroflexi	200795|Chloroflexi	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
REGS1_k127_2064252_0	926569.ANT_13730	4.495e-104	343.0	COG0217@1|root,COG0217@2|Bacteria,2G6AI@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulatory protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
REGS1_k127_2064252_2	926569.ANT_18610	1.482e-73	257.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
REGS1_k127_207809_1	926569.ANT_19100	2.985e-87	294.0	COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM conserved	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
REGS1_k127_207809_6	926569.ANT_03600	5.649e-44	165.0	COG1225@1|root,COG1225@2|Bacteria,2G9KJ@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_207809_3	926569.ANT_30100	1.006e-80	290.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Lactamase_B,Lactamase_B_2,cNMP_binding
REGS1_k127_207809_4	926569.ANT_31550	2.892e-62	219.0	COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi	200795|Chloroflexi	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
REGS1_k127_207809_7	1444309.JAQG01000033_gene2939	2.175e-42	161.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,4HIQX@91061|Bacilli,26YQD@186822|Paenibacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) family	yxbD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Acetyltransf_1
REGS1_k127_207809_0	926569.ANT_31560	3.647e-149	483.0	COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi	200795|Chloroflexi	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
REGS1_k127_207809_9	573413.Spirs_4158	4.846e-31	128.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
REGS1_k127_207809_8	382464.ABSI01000011_gene2976	3.873e-41	157.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_207809_10	1304875.JAFZ01000002_gene391	2.975e-05	49.0	COG1528@1|root,COG1528@2|Bacteria,3TB3G@508458|Synergistetes	508458|Synergistetes	P	Iron-storage protein	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
REGS1_k127_207809_11	1121438.JNJA01000019_gene2766	0.0007322	46.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,2MBEX@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Iron-storage protein	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
REGS1_k127_207809_5	1172188.KB911822_gene707	6.326e-55	207.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4FFYD@85021|Intrasporangiaceae	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GAF_2,HAMP,HATPase_c,HisKA,Response_reg
REGS1_k127_207809_2	926569.ANT_12920	1.458e-85	297.0	COG0455@1|root,COG0745@1|root,COG0455@2|Bacteria,COG0745@2|Bacteria,2G8KV@200795|Chloroflexi	200795|Chloroflexi	KT	AAA domain	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_2113939_0	1120951.AUBG01000007_gene246	1.208e-195	629.0	28HYV@1|root,2Z846@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2113939_2	309801.trd_A0173	9.889e-10	66.0	2A4V4@1|root,30TGQ@2|Bacteria,2GA4W@200795|Chloroflexi,27Z90@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2113939_1	1382356.JQMP01000003_gene1540	5.428e-35	135.0	COG0640@1|root,COG0640@2|Bacteria,2G9T1@200795|Chloroflexi,27ZA0@189775|Thermomicrobia	189775|Thermomicrobia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
REGS1_k127_214262_3	1128421.JAGA01000001_gene2037	9.205e-26	111.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2NRQE@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS,STAS_2
REGS1_k127_214262_2	926569.ANT_27430	8.341e-33	130.0	COG1366@1|root,COG1366@2|Bacteria,2G9DJ@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
REGS1_k127_214262_0	926569.ANT_06180	3.503e-77	277.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
REGS1_k127_225155_3	479434.Sthe_2485	3.176e-24	103.0	COG1225@1|root,COG1225@2|Bacteria,2G95Y@200795|Chloroflexi,27YNE@189775|Thermomicrobia	189775|Thermomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_225155_2	1382356.JQMP01000001_gene1154	2.099e-74	256.0	COG1573@1|root,COG1573@2|Bacteria,2G8DF@200795|Chloroflexi,27YTA@189775|Thermomicrobia	189775|Thermomicrobia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_225155_4	290317.Cpha266_1585	9.61e-19	97.0	COG3621@1|root,COG3621@2|Bacteria	2|Bacteria	AT	Patatin-like phospholipase	-	-	-	ko:K06900	-	-	-	-	ko00000	-	-	-	DUF1735,Laminin_G_3,Patatin
REGS1_k127_225155_1	926569.ANT_19880	2.474e-130	426.0	COG0809@1|root,COG0809@2|Bacteria,2G5UZ@200795|Chloroflexi	200795|Chloroflexi	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
REGS1_k127_225155_5	1123288.SOV_4c01010	7.394e-10	63.0	2DNS1@1|root,32YVX@2|Bacteria,1VEGC@1239|Firmicutes,4H60B@909932|Negativicutes	909932|Negativicutes	S	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
REGS1_k127_225155_0	926569.ANT_19870	3.144e-156	499.0	COG2255@1|root,COG2255@2|Bacteria,2G5QQ@200795|Chloroflexi	200795|Chloroflexi	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
REGS1_k127_2255114_1	180332.JTGN01000003_gene1955	2.23e-48	178.0	COG0395@1|root,COG0395@2|Bacteria,1TSKG@1239|Firmicutes,25C53@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
REGS1_k127_2255114_0	180332.JTGN01000003_gene1954	3.117e-108	364.0	COG4209@1|root,COG4209@2|Bacteria,1TQ64@1239|Firmicutes,24YP3@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
REGS1_k127_2255114_2	180332.JTGN01000003_gene1953	2.187e-15	78.0	COG1653@1|root,COG1653@2|Bacteria,1V8AW@1239|Firmicutes	1239|Firmicutes	G	transport	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
REGS1_k127_2277536_8	1307759.JOMJ01000004_gene2493	2.238e-46	183.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,42T55@68525|delta/epsilon subdivisions,2WPW2@28221|Deltaproteobacteria,2MG3X@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_2277536_7	518766.Rmar_0575	4.505e-50	190.0	COG1215@1|root,COG1215@2|Bacteria,4PM5V@976|Bacteroidetes,1FKEK@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_2277536_6	521011.Mpal_1996	1.957e-51	201.0	COG0438@1|root,arCOG01415@2157|Archaea,2XV2Q@28890|Euryarchaeota,2NA9V@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_2277536_1	443144.GM21_3507	8.483e-94	326.0	COG0438@1|root,COG0438@2|Bacteria,1R6BX@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_2,Glycos_transf_1
REGS1_k127_2277536_3	349161.Dred_1399	3.435e-60	220.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.12	ko:K00694,ko:K11936,ko:K20541	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.2,4.D.1.1.3,4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	BcsB,Glycos_transf_2
REGS1_k127_2277536_2	865937.Gilli_1081	5.349e-75	262.0	COG1216@1|root,COG1216@2|Bacteria,4NK0K@976|Bacteroidetes,1I0UB@117743|Flavobacteriia	976|Bacteroidetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2277536_5	649747.HMPREF0083_02816	2.521e-55	205.0	COG1216@1|root,COG1216@2|Bacteria,1UZHB@1239|Firmicutes,4HFCT@91061|Bacilli,26QB2@186822|Paenibacillaceae	91061|Bacilli	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2277536_4	56780.SYN_02664	1.234e-55	206.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,1RD8N@1224|Proteobacteria,42SZD@68525|delta/epsilon subdivisions,2WPYH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Glycosyl transferase, family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
REGS1_k127_2277536_11	653045.Strvi_8389	6.446e-14	84.0	COG0463@1|root,COG1215@1|root,COG1887@1|root,COG0463@2|Bacteria,COG1215@2|Bacteria,COG1887@2|Bacteria,2I343@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
REGS1_k127_2277536_9	1321815.HMPREF9193_00021	4.021e-37	151.0	2DT0V@1|root,33I77@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2277536_0	118173.KB235914_gene3925	2.23e-124	411.0	COG1134@1|root,COG1134@2|Bacteria,1G28R@1117|Cyanobacteria,1H8CS@1150|Oscillatoriales	1117|Cyanobacteria	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran,Wzt_C
REGS1_k127_2277536_10	521011.Mpal_2173	1.245e-18	86.0	COG1682@1|root,arCOG04339@2157|Archaea,2Y2VQ@28890|Euryarchaeota,2NA8H@224756|Methanomicrobia	224756|Methanomicrobia	P	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
REGS1_k127_2331707_2	926569.ANT_05100	1.342e-69	240.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
REGS1_k127_2331707_1	926569.ANT_00470	2.123e-103	345.0	COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_2331707_0	926569.ANT_02270	6.788e-200	641.0	COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi	200795|Chloroflexi	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
REGS1_k127_2343948_0	749927.AMED_1867	2.344e-47	185.0	COG1807@1|root,COG1807@2|Bacteria,2IASE@201174|Actinobacteria,4E1F3@85010|Pseudonocardiales	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2344149_14	706587.Desti_1382	2.101e-08	59.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,42URY@68525|delta/epsilon subdivisions,2WQYF@28221|Deltaproteobacteria,2MRYS@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_2344149_13	646529.Desaci_3274	1.094e-17	94.0	2ENTF@1|root,33GEM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2344149_9	926569.ANT_27650	1.03e-26	114.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
REGS1_k127_2344149_5	926569.ANT_15430	6.173e-64	226.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
REGS1_k127_2344149_2	1303518.CCALI_01252	6.322e-126	420.0	COG2203@1|root,COG3437@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HATPase_c,HD,HD_5,HWE_HK,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_2344149_11	926569.ANT_02090	3.467e-22	103.0	29Z2W@1|root,30M0E@2|Bacteria,2G9IN@200795|Chloroflexi	200795|Chloroflexi	S	Family of unknown function (DUF5317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5317
REGS1_k127_2344149_0	926569.ANT_04770	8.716e-217	711.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2G6RU@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12
REGS1_k127_2344149_4	926569.ANT_05880	8.858e-75	261.0	COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Inositol monophosphatase	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
REGS1_k127_2344149_3	1128421.JAGA01000001_gene2047	1.17e-112	371.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	rocF	GO:0003674,GO:0003824,GO:0004053,GO:0006082,GO:0006520,GO:0006525,GO:0006807,GO:0008150,GO:0008152,GO:0009064,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
REGS1_k127_2344149_12	388401.RB2150_05393	5.493e-22	104.0	COG3038@1|root,COG3038@2|Bacteria,1PP9T@1224|Proteobacteria,2V9B2@28211|Alphaproteobacteria,3ZIMG@58840|unclassified Rhodobacteraceae	28211|Alphaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_2344149_1	926569.ANT_24850	1.444e-162	523.0	COG1228@1|root,COG1228@2|Bacteria,2G5KM@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM amidohydrolase	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
REGS1_k127_2344149_8	237368.SCABRO_03062	6.902e-36	143.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
REGS1_k127_2344149_6	1121405.dsmv_3084	9.526e-55	208.0	COG0477@1|root,COG2814@2|Bacteria,1R842@1224|Proteobacteria,42QBY@68525|delta/epsilon subdivisions,2WKB6@28221|Deltaproteobacteria,2MHNH@213118|Desulfobacterales	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_2344149_10	926569.ANT_30350	3.84e-24	118.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2344149_7	861299.J421_2299	3.206e-51	192.0	COG4127@1|root,COG4127@2|Bacteria,1ZV3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
REGS1_k127_2344149_15	379066.GAU_3646	3.691e-06	51.0	COG4447@1|root,COG4447@2|Bacteria,1ZSWZ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2352103_0	926569.ANT_11960	0.0	1047.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
REGS1_k127_2352103_1	439235.Dalk_2449	2.861e-36	155.0	COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,42XJQ@68525|delta/epsilon subdivisions,2WSMN@28221|Deltaproteobacteria,2MP2F@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2352103_2	398525.KB900701_gene3756	3.897e-20	104.0	COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,2TSZG@28211|Alphaproteobacteria,3JU5Y@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	MA20_15725	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_2362606_3	177437.HRM2_32130	1.139e-09	66.0	COG0664@1|root,COG0664@2|Bacteria,1N5RB@1224|Proteobacteria,42TH6@68525|delta/epsilon subdivisions,2WQZQ@28221|Deltaproteobacteria,2MKQ7@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_2362606_1	525904.Tter_1443	1.79e-90	305.0	COG3694@1|root,COG3694@2|Bacteria,2NQKI@2323|unclassified Bacteria	2|Bacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
REGS1_k127_2362606_2	1382306.JNIM01000001_gene1764	6.652e-77	266.0	COG4587@1|root,COG4587@2|Bacteria,2G9N0@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
REGS1_k127_2362606_0	525904.Tter_1441	4.68e-140	453.0	COG4586@1|root,COG4586@2|Bacteria,2NP49@2323|unclassified Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_2373376_5	1298867.AUES01000041_gene914	1.741e-07	62.0	2EH3D@1|root,33AVD@2|Bacteria,1QR7N@1224|Proteobacteria,2TUZ2@28211|Alphaproteobacteria,3JXFI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3592)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3592
REGS1_k127_2373376_6	926550.CLDAP_19050	3.242e-05	49.0	COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_2373376_2	926569.ANT_09340	5.752e-84	294.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	1.3.1.74,3.4.21.107	ko:K04771,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_2373376_0	926550.CLDAP_19050	6.469e-186	590.0	COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_2373376_1	926569.ANT_13270	5.223e-92	314.0	COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi	200795|Chloroflexi	GK	PFAM ROK family protein	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
REGS1_k127_2373376_3	1131451.O1K_10967	1.954e-09	70.0	COG0457@1|root,COG0457@2|Bacteria,1R8UZ@1224|Proteobacteria,1RQ7E@1236|Gammaproteobacteria,1X4WX@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
REGS1_k127_238642_2	1304875.JAFZ01000002_gene325	1.533e-64	223.0	COG1132@1|root,COG1132@2|Bacteria,3TA8S@508458|Synergistetes	508458|Synergistetes	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
REGS1_k127_238642_3	1304885.AUEY01000090_gene2886	6.848e-61	213.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2MJPY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
REGS1_k127_238642_0	926569.ANT_03590	8.666e-192	628.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
REGS1_k127_238642_1	926569.ANT_14560	1.838e-79	282.0	COG0790@1|root,COG3359@1|root,COG0790@2|Bacteria,COG3359@2|Bacteria,2G6TK@200795|Chloroflexi	200795|Chloroflexi	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
REGS1_k127_238642_4	696747.NIES39_R00580	0.0001938	48.0	COG1366@1|root,COG1366@2|Bacteria,1G7NW@1117|Cyanobacteria,1HCQQ@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	-	-	-	-	-	-	-	-	-	STAS
REGS1_k127_2386539_0	351160.RCIX2731	2.496e-203	644.0	COG0557@1|root,arCOG04686@2157|Archaea,2XT2E@28890|Euryarchaeota,2NA9N@224756|Methanomicrobia	224756|Methanomicrobia	K	PFAM ribonuclease II	-	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
REGS1_k127_2386539_1	926550.CLDAP_00330	1.337e-79	268.0	COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
REGS1_k127_2401969_4	871968.DESME_07925	6.399e-64	228.0	COG0697@1|root,COG0697@2|Bacteria,1V1H0@1239|Firmicutes,24BBW@186801|Clostridia	186801|Clostridia	EG	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_2401969_1	316274.Haur_4997	7.665e-110	365.0	COG1092@1|root,COG1092@2|Bacteria,2G7Y9@200795|Chloroflexi,3767A@32061|Chloroflexia	32061|Chloroflexia	H	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
REGS1_k127_2401969_6	1499967.BAYZ01000013_gene6423	6.127e-13	77.0	COG4576@1|root,COG4576@2|Bacteria,2NS06@2323|unclassified Bacteria	2|Bacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	eutN	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
REGS1_k127_2401969_8	207559.Dde_3273	4.544e-07	55.0	COG4576@1|root,COG4576@2|Bacteria,1N82T@1224|Proteobacteria,42V6S@68525|delta/epsilon subdivisions,2WRZT@28221|Deltaproteobacteria,2MCQ4@213115|Desulfovibrionales	28221|Deltaproteobacteria	CQ	PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
REGS1_k127_2401969_2	926569.ANT_07270	1.257e-95	317.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BMC
REGS1_k127_2401969_3	926569.ANT_07260	2.937e-87	297.0	COG4820@1|root,COG4820@2|Bacteria	2|Bacteria	E	ethanolamine catabolic process	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,HSP70,MreB_Mbl,PilM_2
REGS1_k127_2401969_5	926569.ANT_07230	3.406e-40	152.0	COG4577@1|root,COG4577@2|Bacteria	2|Bacteria	CQ	ethanolamine catabolic process	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
REGS1_k127_2401969_0	196162.Noca_4031	1.013e-168	542.0	COG1012@1|root,COG1012@2|Bacteria,2GJI2@201174|Actinobacteria,4DQ06@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.10	ko:K00132	ko00620,ko00650,ko01100,ko01120,map00620,map00650,map01100,map01120	-	R00228,R01172	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
REGS1_k127_2401969_7	1203605.HMPREF1531_00752	3.237e-10	61.0	COG4576@1|root,COG4576@2|Bacteria,2GT97@201174|Actinobacteria,4DVTC@85009|Propionibacteriales	201174|Actinobacteria	CQ	Ethanolamine utilisation protein EutN/carboxysome	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
REGS1_k127_2402659_2	690850.Desaf_3456	9.088e-31	127.0	2C6MB@1|root,32951@2|Bacteria,1P561@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2402659_1	234267.Acid_2103	3.971e-147	477.0	COG2382@1|root,COG2382@2|Bacteria,3Y2ZN@57723|Acidobacteria	2|Bacteria	GP	Putative esterase	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase,Glyco_hydro_10
REGS1_k127_2402659_0	861299.J421_5761	1.711e-193	620.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C
REGS1_k127_2406299_2	1172181.KB911699_gene1394	2.156e-31	126.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
REGS1_k127_2406299_1	926569.ANT_29480	3.357e-58	211.0	COG1051@1|root,COG1051@2|Bacteria,2G77J@200795|Chloroflexi	200795|Chloroflexi	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_2406299_0	926569.ANT_07440	5.475e-95	318.0	COG1355@1|root,COG1355@2|Bacteria,2G6V0@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
REGS1_k127_2406299_3	1274374.CBLK010000053_gene2282	4.829e-16	88.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli,26R54@186822|Paenibacillaceae	91061|Bacilli	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
REGS1_k127_2426288_1	326427.Cagg_1164	3.722e-53	199.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi,376N2@32061|Chloroflexia	32061|Chloroflexia	HP	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
REGS1_k127_2426288_2	351160.RCIX701	1.373e-32	130.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
REGS1_k127_2426288_0	926569.ANT_11960	1.726e-176	560.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi	200795|Chloroflexi	H	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13,2.1.1.258	ko:K00548,ko:K15023	ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230	M00017,M00377	R00946,R02289,R09365,R10243	RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
REGS1_k127_2427102_1	926569.ANT_09890	4.171e-172	560.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
REGS1_k127_2427102_9	926569.ANT_09880	4.249e-79	274.0	COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi	2|Bacteria	J	PFAM RNA binding S1 domain protein	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
REGS1_k127_2427102_0	926569.ANT_09870	1.041e-183	594.0	COG1595@1|root,COG1595@2|Bacteria,2GBP1@200795|Chloroflexi	200795|Chloroflexi	K	N-terminal 7TM region of histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
REGS1_k127_2427102_12	926569.ANT_09860	3.229e-32	132.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yyaR	-	-	ko:K06889,ko:K19273	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
REGS1_k127_2427102_11	926569.ANT_09850	8.014e-37	148.0	28RJQ@1|root,2ZDYJ@2|Bacteria,2G9S7@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2427102_7	926569.ANT_09840	2.747e-110	364.0	COG0005@1|root,COG0005@2|Bacteria,2G5KQ@200795|Chloroflexi	200795|Chloroflexi	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_2427102_8	926569.ANT_09820	3.919e-94	332.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,2G97C@200795|Chloroflexi	200795|Chloroflexi	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_2427102_4	926569.ANT_09810	2.38e-129	421.0	COG2008@1|root,COG2008@2|Bacteria,2G5XG@200795|Chloroflexi	200795|Chloroflexi	E	aromatic amino acid beta-eliminating lyase threonine aldolase	gly1	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
REGS1_k127_2427102_6	926569.ANT_09800	9.332e-117	383.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_2427102_10	926569.ANT_09790	1.588e-39	153.0	COG0597@1|root,COG0597@2|Bacteria,2G740@200795|Chloroflexi	200795|Chloroflexi	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
REGS1_k127_2427102_5	1191523.MROS_0930	1.477e-117	389.0	COG0787@1|root,COG0787@2|Bacteria	2|Bacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
REGS1_k127_2427102_3	1128421.JAGA01000004_gene2611	3.604e-144	472.0	COG0031@1|root,COG0031@2|Bacteria,2NP1M@2323|unclassified Bacteria	2|Bacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
REGS1_k127_2427102_2	518766.Rmar_1680	8.459e-151	485.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,4NFUD@976|Bacteroidetes,1FIWE@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	HP	ThiF family	moeZ	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
REGS1_k127_2428780_4	665571.STHERM_c12790	2.378e-105	348.0	COG0438@1|root,COG0438@2|Bacteria,2J6VH@203691|Spirochaetes	203691|Spirochaetes	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
REGS1_k127_2428780_2	926550.CLDAP_06960	4.528e-137	447.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.270	ko:K21369	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_2428780_0	926550.CLDAP_06970	1.156e-198	635.0	COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gpgS	-	2.4.1.266,2.4.1.268	ko:K09118,ko:K13693,ko:K21349	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2,Usp
REGS1_k127_2428780_1	926569.ANT_14450	7.836e-179	563.0	COG2141@1|root,COG2141@2|Bacteria,2G727@200795|Chloroflexi	200795|Chloroflexi	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
REGS1_k127_2428780_3	768706.Desor_1364	2.97e-133	437.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,26000@186807|Peptococcaceae	186801|Clostridia	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	ssnA	-	3.5.4.28,3.5.4.31,3.5.4.40	ko:K12960,ko:K20810	ko00130,ko00270,ko01100,ko01110,map00130,map00270,map01100,map01110	-	R09660,R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
REGS1_k127_2428780_5	459349.CLOAM1631	2.851e-41	155.0	COG0167@1|root,COG0493@1|root,COG1148@1|root,COG0167@2|Bacteria,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	pds	-	1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9	ko:K00207,ko:K00219,ko:K00317,ko:K02293,ko:K10797,ko:K12527,ko:K17723	ko00240,ko00360,ko00410,ko00450,ko00680,ko00770,ko00906,ko00983,ko01100,ko01110,ko01120,ko01200,map00240,map00360,map00410,map00450,map00680,map00770,map00906,map00983,map01100,map01110,map01120,map01200	M00046,M00097	R00977,R00978,R01414,R01415,R01588,R02252,R02511,R04786,R04787,R07229,R07510,R08226,R09652,R09653,R09654,R11026	RC00072,RC00123,RC00185,RC00556,RC00557,RC00669,RC00732,RC01214,RC01958,RC02245,RC02420,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4,Fer4_4,Pyr_redox_2
REGS1_k127_24289_0	404589.Anae109_0223	6.601e-37	144.0	COG4914@1|root,COG4914@2|Bacteria,1N1W1@1224|Proteobacteria,42VPD@68525|delta/epsilon subdivisions,2WS3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_24289_1	395965.Msil_3917	2.24e-24	115.0	COG3409@1|root,COG3409@2|Bacteria,1P10K@1224|Proteobacteria,2UV2K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_24289_2	1121106.JQKB01000122_gene3952	8.969e-07	51.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,2TQWC@28211|Alphaproteobacteria,2JX0B@204441|Rhodospirillales	204441|Rhodospirillales	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	-	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
REGS1_k127_2430912_2	926569.ANT_15310	3.549e-77	267.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_2430912_0	926569.ANT_15320	1.927e-135	445.0	COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cytoplasmic peptidoglycan synthetase domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
REGS1_k127_2430912_3	479432.Sros_0687	1.689e-27	116.0	COG0537@1|root,COG0537@2|Bacteria	2|Bacteria	FG	bis(5'-adenosyl)-triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4269
REGS1_k127_2430912_4	926569.ANT_22500	1.099e-25	108.0	COG1550@1|root,COG1550@2|Bacteria,2G765@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
REGS1_k127_2430912_1	335543.Sfum_1736	1.261e-100	337.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,43DN9@68525|delta/epsilon subdivisions,2X25J@28221|Deltaproteobacteria,2MS0P@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
REGS1_k127_2430912_5	706587.Desti_4722	3.419e-18	85.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
REGS1_k127_2452095_1	926569.ANT_23780	1.678e-23	111.0	COG1388@1|root,COG2340@1|root,COG1388@2|Bacteria,COG2340@2|Bacteria,2G9SX@200795|Chloroflexi	200795|Chloroflexi	M	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
REGS1_k127_2452095_0	926569.ANT_29930	1.025e-88	301.0	COG2116@1|root,COG2116@2|Bacteria,2G967@200795|Chloroflexi	200795|Chloroflexi	P	Formate/nitrite transporter	-	-	-	ko:K06212	-	-	-	-	ko00000,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	Form_Nir_trans
REGS1_k127_2460560_1	864051.BurJ1DRAFT_2685	6.272e-121	400.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_2460560_0	864051.BurJ1DRAFT_2684	2.349e-223	702.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,2VKHA@28216|Betaproteobacteria,1KN5Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
REGS1_k127_2460560_2	926569.ANT_27650	8.393e-28	117.0	COG0640@1|root,COG0640@2|Bacteria,2G9FC@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
REGS1_k127_2460560_3	926569.ANT_15430	1.163e-12	69.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,2G7GS@200795|Chloroflexi	200795|Chloroflexi	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
REGS1_k127_2467978_1	926569.ANT_29500	2.274e-62	221.0	COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi	200795|Chloroflexi	K	sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_2467978_3	266117.Rxyl_1923	2.493e-05	50.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
REGS1_k127_2467978_2	710686.Mycsm_03429	3.037e-28	119.0	COG4747@1|root,COG4747@2|Bacteria	2|Bacteria	-	-	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
REGS1_k127_2467978_0	926569.ANT_04940	2.081e-75	256.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
REGS1_k127_2475614_2	1234409.C683_0811	9.913e-08	58.0	COG1388@1|root,COG1388@2|Bacteria,1VA10@1239|Firmicutes,4HMUH@91061|Bacilli,4B62W@81852|Enterococcaceae	91061|Bacilli	M	LysM domain	lytE	-	-	-	-	-	-	-	-	-	-	-	LysM
REGS1_k127_2475614_1	926569.ANT_13230	1.239e-18	93.0	COG0268@1|root,COG0268@2|Bacteria,2G7AK@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
REGS1_k127_2475614_0	926569.ANT_13220	9.279e-176	569.0	COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi	200795|Chloroflexi	J	Arginyl-tRNA synthetase	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
REGS1_k127_2476464_0	926569.ANT_14080	1.155e-160	510.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_2476464_3	926569.ANT_26550	2.05e-65	235.0	COG3212@1|root,COG3212@2|Bacteria	2|Bacteria	T	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
REGS1_k127_2476464_2	926569.ANT_26560	2.421e-92	308.0	COG0745@1|root,COG0745@2|Bacteria,2G8EK@200795|Chloroflexi	200795|Chloroflexi	K	PFAM response regulator receiver	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_2476464_1	926569.ANT_26570	9.169e-113	376.0	COG5002@1|root,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	2.7.13.3	ko:K10819	-	-	-	-	ko00000,ko01000	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_2476464_4	1192034.CAP_7043	4.858e-50	194.0	2C4HX@1|root,2Z9XP@2|Bacteria,1MY22@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2476464_5	926569.ANT_17350	2.155e-42	165.0	COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
REGS1_k127_2478668_5	1120746.CCNL01000017_gene2423	1.331e-10	68.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
REGS1_k127_2478668_2	1313172.YM304_06270	4.523e-73	266.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
REGS1_k127_2478668_0	1128421.JAGA01000002_gene314	6.876e-95	321.0	COG1131@1|root,COG1131@2|Bacteria,2NQPB@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_2478668_3	1120746.CCNL01000017_gene2423	4.762e-73	258.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
REGS1_k127_2478668_8	196490.AUEZ01000028_gene1937	8.782e-05	48.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,2TSUK@28211|Alphaproteobacteria,3JUZP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Zinc-binding dehydrogenase	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_2478668_4	717605.Theco_2490	9.024e-14	83.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli,26R7U@186822|Paenibacillaceae	91061|Bacilli	S	Permease	yrrI	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_2478668_1	1128421.JAGA01000002_gene1281	3.016e-83	291.0	COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria	2|Bacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_2478668_6	682795.AciX8_0654	5.398e-09	60.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2478668_9	289376.THEYE_A0128	0.0003809	48.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
REGS1_k127_2492364_4	926569.ANT_15750	4.208e-90	306.0	COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_2492364_3	479434.Sthe_1933	2.718e-99	338.0	COG0508@1|root,COG0508@2|Bacteria,2G619@200795|Chloroflexi,27Y2C@189775|Thermomicrobia	189775|Thermomicrobia	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
REGS1_k127_2492364_1	926569.ANT_14270	1.01e-180	571.0	COG0022@1|root,COG0022@2|Bacteria,2G60F@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Transketolase central region	-	-	1.2.4.1,1.2.4.4	ko:K00162,ko:K11381,ko:K21417	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
REGS1_k127_2492364_2	926569.ANT_14260	4.159e-147	472.0	COG1071@1|root,COG1071@2|Bacteria,2G5SF@200795|Chloroflexi	200795|Chloroflexi	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
REGS1_k127_2492364_5	525904.Tter_2170	1.176e-46	175.0	COG0778@1|root,COG0778@2|Bacteria,2NRS1@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	ydjA	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_2492364_0	926569.ANT_14230	2.242e-219	688.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2G5W2@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_2512044_2	1123251.ATWM01000001_gene706	9.158e-57	209.0	COG3302@1|root,COG3302@2|Bacteria,2GV8F@201174|Actinobacteria	201174|Actinobacteria	S	DMSO reductase anchor subunit (DmsC)	dmsC	-	-	ko:K07308	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	DmsC
REGS1_k127_2512044_1	1123251.ATWM01000001_gene707	8.434e-83	279.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria,4FF0K@85021|Intrasporangiaceae	201174|Actinobacteria	C	4Fe-4S dicluster domain	dmsB	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11,Fer4_3,Fer4_4
REGS1_k127_2512044_0	264732.Moth_1389	0.0	1112.0	COG0243@1|root,COG0243@2|Bacteria,1TPZG@1239|Firmicutes,247JV@186801|Clostridia,42HRB@68295|Thermoanaerobacterales	186801|Clostridia	C	Molydopterin dinucleotide binding domain	-	-	1.7.2.3,1.8.5.3	ko:K07306,ko:K07812	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko01000,ko02000	5.A.3.3,5.A.3.4	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
REGS1_k127_2513282_3	1532557.JL37_22530	1.847e-09	69.0	2DV6A@1|root,33UBF@2|Bacteria,1NVFT@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2513282_0	926569.ANT_05370	1.277e-172	552.0	COG2723@1|root,COG2723@2|Bacteria,2G5QE@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase, family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
REGS1_k127_2513282_2	383372.Rcas_1195	1.357e-09	64.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2G93H@200795|Chloroflexi,375J3@32061|Chloroflexia	32061|Chloroflexia	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	2.7.11.1	ko:K04749,ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,STAS
REGS1_k127_2513282_1	926569.ANT_30550	2.291e-77	267.0	COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
REGS1_k127_2530926_0	338969.Rfer_3659	4.253e-156	501.0	COG2271@1|root,COG2271@2|Bacteria,1QZ70@1224|Proteobacteria,2WHIE@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_2530926_1	911045.PSE_p0146	2.908e-62	228.0	COG3385@1|root,COG3385@2|Bacteria,1RCTP@1224|Proteobacteria,2UPV7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
REGS1_k127_2531483_0	330214.NIDE3296	7.281e-292	899.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
REGS1_k127_2531483_1	330214.NIDE3299	1.503e-61	214.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
REGS1_k127_25370_3	682795.AciX8_0654	2.637e-07	54.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_25370_5	1232410.KI421424_gene1753	5.647e-05	50.0	COG4980@1|root,COG4980@2|Bacteria,1NEPD@1224|Proteobacteria,42WE2@68525|delta/epsilon subdivisions,2WRDT@28221|Deltaproteobacteria,43SRZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
REGS1_k127_25370_0	479434.Sthe_2550	4.166e-21	98.0	COG0762@1|root,COG0762@2|Bacteria,2G9JK@200795|Chloroflexi,27ZAJ@189775|Thermomicrobia	189775|Thermomicrobia	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_25370_2	1128421.JAGA01000002_gene949	2.844e-16	81.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	mltA	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
REGS1_k127_25370_1	247490.KSU1_C0653	8.374e-17	84.0	COG3237@1|root,COG3237@2|Bacteria,2J0JU@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
REGS1_k127_2543870_2	2002.JOEQ01000005_gene3526	2.474e-40	156.0	2CBRB@1|root,33SV2@2|Bacteria,2IJ64@201174|Actinobacteria,4EJ8Z@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2543870_5	926550.CLDAP_34200	2.029e-20	92.0	2E5PY@1|root,330EK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2543870_1	1128421.JAGA01000002_gene351	6.915e-102	339.0	COG0414@1|root,COG0414@2|Bacteria,2NP0J@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
REGS1_k127_2543870_0	292564.Cyagr_0200	9.345e-119	391.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
REGS1_k127_2543870_7	1286093.C266_24318	1.595e-15	85.0	COG0454@1|root,COG0456@2|Bacteria,1QU9D@1224|Proteobacteria,2VUVY@28216|Betaproteobacteria,1KIF4@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
REGS1_k127_2543870_3	316274.Haur_3232	1.516e-38	162.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,Trans_reg_C
REGS1_k127_2543870_8	1120972.AUMH01000013_gene2438	6.493e-10	63.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,4HIHA@91061|Bacilli,27A34@186823|Alicyclobacillaceae	91061|Bacilli	S	Cyclic-di-AMP receptor	yaaQ	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
REGS1_k127_2543870_4	926569.ANT_04420	7.627e-30	123.0	COG3870@1|root,COG3870@2|Bacteria	2|Bacteria	S	Cyclic-di-AMP receptor	-	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
REGS1_k127_2543870_6	316274.Haur_2980	1.132e-16	94.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	ko:K12204	-	-	-	-	ko00000,ko02044	3.A.7.10.1,3.A.7.9.1	-	-	DUF2235,FecR,LysM
REGS1_k127_2543870_9	926550.CLDAP_12350	4.185e-06	57.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
REGS1_k127_2562456_6	926569.ANT_28150	2.195e-10	64.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
REGS1_k127_2562456_2	926569.ANT_22510	3.849e-88	299.0	COG1028@1|root,COG1028@2|Bacteria,2G6GQ@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.140	ko:K00059,ko:K00068	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R05607,R07759,R07763,R10116,R10120,R11671	RC00029,RC00085,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_2562456_1	706587.Desti_4719	1.66e-144	464.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
REGS1_k127_2562456_0	706587.Desti_4720	1.363e-147	473.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42V9Y@68525|delta/epsilon subdivisions,2WND5@28221|Deltaproteobacteria,2MS8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	D	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
REGS1_k127_2562456_4	706587.Desti_4721	1.125e-36	140.0	2DZFA@1|root,32V98@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2562456_5	706587.Desti_4721	4.032e-22	104.0	2DZFA@1|root,32V98@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2562456_7	1128421.JAGA01000003_gene3244	1.934e-08	63.0	2EMGM@1|root,33F5A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2562456_3	706587.Desti_4722	2.993e-61	227.0	COG1966@1|root,COG1966@2|Bacteria,1MWF9@1224|Proteobacteria,42NBI@68525|delta/epsilon subdivisions,2WM33@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	carbon starvation protein CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
REGS1_k127_2568572_26	926569.ANT_06810	5.518e-39	147.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_06810|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2568572_10	1128421.JAGA01000002_gene1836	2.549e-86	300.0	COG2189@1|root,COG2189@2|Bacteria,2NP0F@2323|unclassified Bacteria	2|Bacteria	L	PFAM DNA methylase N-4 N-6	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
REGS1_k127_2568572_13	926569.ANT_15760	9.311e-79	276.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_2568572_29	479434.Sthe_3345	4.237e-32	132.0	COG1595@1|root,COG1595@2|Bacteria,2G6UE@200795|Chloroflexi,27YF3@189775|Thermomicrobia	189775|Thermomicrobia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_2568572_31	1463895.JODA01000010_gene7071	9.978e-21	101.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria	201174|Actinobacteria	K	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
REGS1_k127_2568572_30	448385.sce0138	2.575e-23	101.0	COG4430@1|root,COG4430@2|Bacteria,1NASK@1224|Proteobacteria,43202@68525|delta/epsilon subdivisions,2WX2P@28221|Deltaproteobacteria,2Z2U2@29|Myxococcales	28221|Deltaproteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
REGS1_k127_2568572_15	649638.Trad_0250	5.723e-72	249.0	COG2258@1|root,COG2258@2|Bacteria,1WMGC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
REGS1_k127_2568572_17	381666.H16_A2890	5.062e-66	246.0	2CMVP@1|root,32SFM@2|Bacteria,1N5AA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2568572_0	552811.Dehly_0399	2.34e-248	781.0	COG1132@1|root,COG1132@2|Bacteria,2G5P7@200795|Chloroflexi,34CKH@301297|Dehalococcoidia	301297|Dehalococcoidia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_2568572_34	485913.Krac_8476	9.678e-13	74.0	COG3794@1|root,COG3794@2|Bacteria,2G7GX@200795|Chloroflexi	200795|Chloroflexi	C	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1
REGS1_k127_2568572_28	1121933.AUHH01000024_gene2921	1.001e-34	139.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
REGS1_k127_2568572_9	357808.RoseRS_2229	2.23e-88	314.0	COG0515@1|root,COG0515@2|Bacteria,2G7ZS@200795|Chloroflexi,3757W@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
REGS1_k127_2568572_8	926569.ANT_14140	1.954e-94	316.0	COG0313@1|root,COG0313@2|Bacteria,2G6E3@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
REGS1_k127_2568572_4	1128421.JAGA01000001_gene2141	7.36e-193	614.0	COG2939@1|root,COG2939@2|Bacteria	2|Bacteria	E	PFAM Peptidase S10, serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
REGS1_k127_2568572_33	292459.STH1911	4.893e-16	91.0	2DTCK@1|root,33JQD@2|Bacteria,1VNW3@1239|Firmicutes,24X19@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2568572_21	765420.OSCT_1998	7.694e-53	206.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_2568572_24	926569.ANT_06510	2.533e-46	187.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	PMT_2
REGS1_k127_2568572_6	926569.ANT_14150	6.072e-103	350.0	COG0449@1|root,COG0449@2|Bacteria	2|Bacteria	M	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	-	-	2.6.1.16,5.3.1.8,5.3.1.9	ko:K00820,ko:K15916	ko00010,ko00030,ko00051,ko00250,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko04931,map00010,map00030,map00051,map00250,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map04931	M00001,M00004,M00114	R00768,R01819,R02739,R02740,R03321	RC00010,RC00163,RC00376,RC00563,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	SIS
REGS1_k127_2568572_7	926569.ANT_05580	5.017e-98	327.0	COG0496@1|root,COG0496@2|Bacteria,2G6XI@200795|Chloroflexi	200795|Chloroflexi	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
REGS1_k127_2568572_5	880073.Calab_0989	5.514e-149	478.0	COG0667@1|root,COG0667@2|Bacteria,2NP23@2323|unclassified Bacteria	2|Bacteria	C	Aldo/keto reductase family	yghZ	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
REGS1_k127_2568572_32	1304275.C41B8_02372	3.222e-19	91.0	COG3695@1|root,COG3695@2|Bacteria,1N7J2@1224|Proteobacteria,1SCIZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	methylated DNA-protein cysteine methyltransferase	ybaZ	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
REGS1_k127_2568572_22	671143.DAMO_0654	1.519e-52	190.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
REGS1_k127_2568572_3	671143.DAMO_0652	5.888e-221	692.0	COG0183@1|root,COG0183@2|Bacteria,2NP9T@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_2568572_27	1121481.AUAS01000006_gene588	6.387e-38	148.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
REGS1_k127_2568572_35	522373.Smlt0450	4.712e-10	67.0	2DQJ5@1|root,3376Z@2|Bacteria,1QZPW@1224|Proteobacteria,1SU5N@1236|Gammaproteobacteria,1XBMZ@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2568572_14	32507.XP_006788221.1	1.853e-78	271.0	COG2301@1|root,2QQPK@2759|Eukaryota,38GJH@33154|Opisthokonta,3BAH3@33208|Metazoa,3CUC8@33213|Bilateria,482FQ@7711|Chordata,48Z08@7742|Vertebrata,49RTX@7898|Actinopterygii	33208|Metazoa	F	Citrate lyase	CLYBL	GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0019222,GO:0022607,GO:0030656,GO:0031323,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0046912,GO:0047777,GO:0050789,GO:0050794,GO:0051171,GO:0051193,GO:0051259,GO:0051260,GO:0062012,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0071840,GO:0106064,GO:1901401	-	ko:K11390	-	-	-	-	ko00000,ko01000	-	-	-	HpcH_HpaI
REGS1_k127_2568572_11	1173026.Glo7428_2690	2.829e-84	288.0	COG1028@1|root,COG1028@2|Bacteria,1G67A@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_2568572_18	439235.Dalk_5022	2.791e-64	230.0	COG0697@1|root,COG0697@2|Bacteria,1R03B@1224|Proteobacteria,42S5I@68525|delta/epsilon subdivisions,2WNXS@28221|Deltaproteobacteria,2MNCD@213118|Desulfobacterales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_2568572_19	1089551.KE386572_gene3286	5.119e-59	213.0	COG1028@1|root,COG1028@2|Bacteria,1MXVZ@1224|Proteobacteria,2VFPM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
REGS1_k127_2568572_36	543632.JOJL01000007_gene5501	1.645e-07	59.0	COG1846@1|root,COG1846@2|Bacteria,2GPQ8@201174|Actinobacteria,4DFCW@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
REGS1_k127_2568572_2	316274.Haur_0948	2.099e-232	738.0	COG1132@1|root,COG1132@2|Bacteria,2G5RP@200795|Chloroflexi,376W8@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_2568572_1	926550.CLDAP_22330	1.949e-242	766.0	COG1132@1|root,COG1132@2|Bacteria,2G63W@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_2568572_12	765698.Mesci_1804	9.21e-79	281.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2TSS7@28211|Alphaproteobacteria,43GTD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Osmosensitive K channel histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
REGS1_k127_2568572_16	1957.JODX01000028_gene5850	1.485e-70	250.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_2568572_23	671143.DAMO_1519	9.961e-52	208.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_2568572_20	671143.DAMO_1520	3.239e-57	207.0	COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
REGS1_k127_2568572_25	1105031.HMPREF1141_1721	3.109e-39	149.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,36ERV@31979|Clostridiaceae	186801|Clostridia	P	domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
REGS1_k127_258498_6	485913.Krac_8232	3.315e-24	109.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_258498_3	1379698.RBG1_1C00001G0533	1.158e-82	287.0	COG0454@1|root,COG0456@2|Bacteria,2NNUP@2323|unclassified Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_258498_4	1499967.BAYZ01000009_gene5260	3.131e-43	166.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_258498_0	926550.CLDAP_06400	0.0	1091.0	COG3383@1|root,COG3383@2|Bacteria,2GBH3@200795|Chloroflexi	200795|Chloroflexi	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
REGS1_k127_258498_2	926550.CLDAP_05930	6.053e-101	333.0	COG3383@1|root,COG3383@2|Bacteria	2|Bacteria	C	formate dehydrogenase (NAD+) activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_7,Molybdop_Fe4S4,cNMP_binding
REGS1_k127_258498_1	1121385.AQXW01000004_gene1609	6.267e-160	524.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.17.1.9,1.6.5.3	ko:K00122,ko:K00335	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_258498_5	404380.Gbem_1627	9.189e-38	160.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	Cu-binding_MopE,Sulfatase
REGS1_k127_259974_1	1382356.JQMP01000003_gene2462	1.314e-75	259.0	COG0626@1|root,COG0626@2|Bacteria,2G684@200795|Chloroflexi,27Y2Y@189775|Thermomicrobia	189775|Thermomicrobia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.11	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_259974_0	926569.ANT_15490	6.46e-223	702.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_2610677_0	1100721.ALKO01000020_gene911	5.059e-148	474.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9Z9@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_2610677_1	926569.ANT_08530	2.657e-146	468.0	COG1087@1|root,COG1087@2|Bacteria,2G8A8@200795|Chloroflexi	200795|Chloroflexi	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_2610677_3	926569.ANT_08510	7.837e-62	220.0	COG2094@1|root,COG2094@2|Bacteria,2G77D@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
REGS1_k127_2610677_2	383372.Rcas_3406	5.263e-99	332.0	COG0623@1|root,COG0623@2|Bacteria,2G6ED@200795|Chloroflexi,375AJ@32061|Chloroflexia	32061|Chloroflexia	I	Enoyl- acyl-carrier-protein reductase NADH	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_2619263_1	329726.AM1_0728	2.014e-57	207.0	COG0300@1|root,COG0300@2|Bacteria,1GQJ4@1117|Cyanobacteria	1117|Cyanobacteria	L	KR domain	-	-	1.1.1.102	ko:K04708	ko00600,ko01100,map00600,map01100	M00094,M00099	R02978	RC00089	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short
REGS1_k127_2619263_2	1123392.AQWL01000002_gene2115	4.112e-20	91.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,1KRT0@119069|Hydrogenophilales	119069|Hydrogenophilales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_2619263_0	926569.ANT_27410	8.253e-165	527.0	COG0525@1|root,COG0525@2|Bacteria,2G5VS@200795|Chloroflexi	200795|Chloroflexi	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
REGS1_k127_2632089_1	195253.Syn6312_1966	1.061e-09	64.0	COG1487@1|root,COG1487@2|Bacteria	195253.Syn6312_1966|-	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2632089_0	1382359.JIAL01000001_gene1665	6.312e-117	386.0	COG1626@1|root,COG1626@2|Bacteria,3Y3SJ@57723|Acidobacteria,2JIHN@204432|Acidobacteriia	204432|Acidobacteriia	G	Trehalase	-	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase
REGS1_k127_2654923_5	880073.Calab_1356	2.541e-16	91.0	COG1305@1|root,COG1305@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	TIG,Transglut_core
REGS1_k127_2654923_2	1121127.JAFA01000007_gene5326	1.417e-98	333.0	COG1879@1|root,COG1879@2|Bacteria,1MV17@1224|Proteobacteria,2W9DW@28216|Betaproteobacteria,1K6GW@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
REGS1_k127_2654923_1	1121127.JAFA01000007_gene5325	2.133e-100	338.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2WAQR@28216|Betaproteobacteria,1K3VE@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
REGS1_k127_2654923_3	349163.Acry_0319	3.613e-87	297.0	COG1129@1|root,COG1129@2|Bacteria,1MW4I@1224|Proteobacteria,2VFEX@28211|Alphaproteobacteria,2JWD2@204441|Rhodospirillales	204441|Rhodospirillales	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
REGS1_k127_2654923_4	580327.Tthe_0668	1.339e-85	288.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,42FT4@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Class II aldolase adducin	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
REGS1_k127_2654923_0	926569.ANT_13670	8.246e-281	872.0	COG1069@1|root,COG1069@2|Bacteria,2G8AT@200795|Chloroflexi	200795|Chloroflexi	C	FGGY family of carbohydrate kinases, N-terminal domain	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
REGS1_k127_2655585_2	485913.Krac_5562	6.948e-154	490.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	200795|Chloroflexi	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_2655585_13	926569.ANT_31280	1.809e-51	187.0	COG4087@1|root,COG4087@2|Bacteria,2G99M@200795|Chloroflexi	200795|Chloroflexi	S	Haloacid dehalogenase domain protein hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
REGS1_k127_2655585_14	926569.ANT_31270	4.036e-49	192.0	COG1808@1|root,COG1808@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF389
REGS1_k127_2655585_0	926569.ANT_31260	1.687e-228	716.0	COG1109@1|root,COG1109@2|Bacteria,2G5PR@200795|Chloroflexi	200795|Chloroflexi	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_2655585_18	1340493.JNIF01000004_gene1024	1.596e-21	109.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
REGS1_k127_2655585_5	489825.LYNGBM3L_57620	1.125e-107	373.0	COG1807@1|root,COG1807@2|Bacteria,1G0W2@1117|Cyanobacteria,1H9QQ@1150|Oscillatoriales	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_2655585_7	926569.ANT_00400	1.666e-87	301.0	28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2655585_3	926569.ANT_00390	4.045e-139	462.0	COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi	200795|Chloroflexi	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	MutL
REGS1_k127_2655585_15	926569.ANT_00380	1.847e-37	149.0	2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2655585_9	926569.ANT_00370	1.125e-64	249.0	COG1187@1|root,COG1187@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	rluB	-	5.4.99.19,5.4.99.20,5.4.99.22	ko:K06178,ko:K06181,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_2655585_16	926569.ANT_00360	4.605e-33	137.0	2EA58@1|root,334A5@2|Bacteria,2G7FD@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2655585_12	926569.ANT_00350	1.363e-54	200.0	28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2655585_10	926569.ANT_12670	1.217e-61	214.0	COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi	200795|Chloroflexi	I	PFAM cobalamin B12-binding domain protein	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
REGS1_k127_2655585_6	926569.ANT_12660	3.902e-99	335.0	COG1703@1|root,COG1703@2|Bacteria,2G670@200795|Chloroflexi	200795|Chloroflexi	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
REGS1_k127_2655585_11	926569.ANT_12640	3.261e-61	217.0	COG1670@1|root,COG1670@2|Bacteria,2G73Y@200795|Chloroflexi	200795|Chloroflexi	J	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
REGS1_k127_2655585_4	926569.ANT_12630	8.254e-129	420.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
REGS1_k127_2655585_8	926569.ANT_12620	7.089e-87	295.0	COG0266@1|root,COG0266@2|Bacteria,2G6BB@200795|Chloroflexi	200795|Chloroflexi	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
REGS1_k127_2655585_20	1382356.JQMP01000003_gene2296	2.174e-19	96.0	COG0406@1|root,COG0406@2|Bacteria,2G726@200795|Chloroflexi,27Z7X@189775|Thermomicrobia	189775|Thermomicrobia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
REGS1_k127_2655585_17	926550.CLDAP_06540	7.015e-27	122.0	COG1985@1|root,COG1985@2|Bacteria	2|Bacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_2655585_1	235985.BBPN01000040_gene354	5.609e-193	614.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria,2NKRD@228398|Streptacidiphilus	201174|Actinobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
REGS1_k127_2698891_0	1121405.dsmv_3003	0.0	2409.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_270331_2	56110.Oscil6304_3951	4.058e-07	55.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_7,PAS_8,PAS_9,Response_reg
REGS1_k127_270331_1	420662.Mpe_A0582	1.914e-22	113.0	COG0784@1|root,COG4585@1|root,COG0784@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,1KJJ7@119065|unclassified Burkholderiales	28216|Betaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_3,PAS_9,Response_reg
REGS1_k127_270331_0	331113.SNE_B24410	2.331e-219	701.0	COG0058@1|root,COG0058@2|Bacteria,2JFEH@204428|Chlamydiae	204428|Chlamydiae	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_2713424_3	765420.OSCT_2611	5.258e-18	87.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,376G0@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
REGS1_k127_2713424_0	383372.Rcas_3796	2.607e-166	529.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,376PX@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
REGS1_k127_2713424_2	357808.RoseRS_0973	2.988e-27	115.0	COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi,377Q5@32061|Chloroflexia	32061|Chloroflexia	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
REGS1_k127_2713424_1	926569.ANT_17860	6.385e-116	384.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
REGS1_k127_2722317_3	926569.ANT_30890	2.834e-58	212.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
REGS1_k127_2722317_0	926569.ANT_23480	0.0	1283.0	COG0209@1|root,COG0209@2|Bacteria,2G5PW@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Intein_splicing,Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
REGS1_k127_2722317_2	926569.ANT_23470	1.296e-63	221.0	COG1327@1|root,COG1327@2|Bacteria,2G6QI@200795|Chloroflexi	200795|Chloroflexi	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
REGS1_k127_2722317_1	754252.PFREUD_03340	2.38e-73	256.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4DQX3@85009|Propionibacteriales	201174|Actinobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
REGS1_k127_2765528_6	693986.MOC_5737	8.993e-20	103.0	COG4564@1|root,COG4564@2|Bacteria,1N7FX@1224|Proteobacteria,2V00M@28211|Alphaproteobacteria,1JV8U@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	Cache_2	-	-	-	-	-	-	-	-	-	-	-	-	dCache_2
REGS1_k127_2765528_2	1165841.SULAR_03802	6.632e-63	233.0	COG4564@1|root,COG4564@2|Bacteria,1N7NM@1224|Proteobacteria,42W17@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM Cache	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	dCache_2,sCache_2
REGS1_k127_2765528_4	267608.RSc0133	7.955e-30	121.0	COG4274@1|root,COG4274@2|Bacteria,1MZVV@1224|Proteobacteria,2VUPM@28216|Betaproteobacteria,1K8BT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM GYD family protein	-	-	-	-	-	-	-	-	-	-	-	-	GYD
REGS1_k127_2765528_5	1454004.AW11_02570	1.374e-29	120.0	COG4274@1|root,COG4274@2|Bacteria,1MZVV@1224|Proteobacteria,2VUPM@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM GYD family protein	-	-	-	-	-	-	-	-	-	-	-	-	GYD
REGS1_k127_2765528_3	1031711.RSPO_c03231	4.446e-31	125.0	COG4274@1|root,COG4274@2|Bacteria,1MZVV@1224|Proteobacteria,2VUPM@28216|Betaproteobacteria,1K8BT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM GYD family protein	-	-	-	-	-	-	-	-	-	-	-	-	GYD
REGS1_k127_2765528_1	1173028.ANKO01000020_gene5550	2.682e-93	316.0	COG0596@1|root,COG0596@2|Bacteria,1G3EV@1117|Cyanobacteria,1HIAJ@1150|Oscillatoriales	1117|Cyanobacteria	E	Serine aminopeptidase, S33	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
REGS1_k127_2765528_0	330214.NIDE0049	1.25e-107	353.0	COG1028@1|root,COG1028@2|Bacteria,3J0J6@40117|Nitrospirae	330214.NIDE0049|-	IQ	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
REGS1_k127_2769467_0	1041522.MCOL_V208920	9.185e-264	824.0	COG2224@1|root,COG2224@2|Bacteria,2I926@201174|Actinobacteria,232A9@1762|Mycobacteriaceae	201174|Actinobacteria	C	Isocitrate lyase	aceAb	GO:0003674,GO:0003824,GO:0004451,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0006102,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046421,GO:0046487,GO:0071704,GO:0072350	4.1.3.1	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	M00012	R00479	RC00311,RC00313	ko00000,ko00001,ko00002,ko01000	-	-	-	ICL
REGS1_k127_2769467_3	234267.Acid_7011	0.0002242	50.0	COG0628@1|root,COG0628@2|Bacteria,3Y4N5@57723|Acidobacteria	57723|Acidobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_2769467_1	1095769.CAHF01000022_gene153	3.232e-80	284.0	COG0586@1|root,COG0671@1|root,COG0586@2|Bacteria,COG0671@2|Bacteria,1R0F3@1224|Proteobacteria,2VTF9@28216|Betaproteobacteria	28216|Betaproteobacteria	I	SNARE associated Golgi protein	yabI_1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LssY_C,PAP2,SNARE_assoc
REGS1_k127_2769467_2	234267.Acid_7306	1.512e-66	231.0	29PPX@1|root,30AN2@2|Bacteria,3Y4HQ@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2801099_2	632245.CLP_0389	8.204e-53	199.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,36DY8@31979|Clostridiaceae	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
REGS1_k127_2801099_1	926569.ANT_02970	5.527e-137	445.0	COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi	200795|Chloroflexi	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	-	-	-	-	-	-	-	-	-	Bmp
REGS1_k127_2801099_0	926569.ANT_02980	1.354e-149	483.0	COG3845@1|root,COG3845@2|Bacteria	2|Bacteria	P	ABC transporter	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
REGS1_k127_2804905_1	926569.ANT_25980	2.108e-61	216.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
REGS1_k127_2804905_0	926569.ANT_25960	1.148e-160	513.0	COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
REGS1_k127_2804905_2	587753.EY04_18950	1.001e-26	109.0	COG0166@1|root,COG0166@2|Bacteria,1PQU4@1224|Proteobacteria,1RVUJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the GPI family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
REGS1_k127_2820062_3	760192.Halhy_1193	1.93e-66	239.0	COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,1IXTS@117747|Sphingobacteriia	976|Bacteroidetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_2820062_4	1379698.RBG1_1C00001G0658	2.547e-65	230.0	arCOG08955@1|root,2ZN6H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2820062_2	1282361.ABAC402_17765	5.103e-71	249.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
REGS1_k127_2820062_6	1150398.JIBJ01000003_gene1491	3.975e-34	135.0	COG3832@1|root,COG3832@2|Bacteria,2I61C@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
REGS1_k127_2820062_1	1242864.D187_000281	5.247e-81	289.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,42WQU@68525|delta/epsilon subdivisions,2WTEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Inosine-uridine preferring nucleoside hydrolase	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
REGS1_k127_2820062_5	1192124.LIG30_3482	1.799e-47	181.0	COG1357@1|root,COG1357@2|Bacteria,1NGZN@1224|Proteobacteria	1224|Proteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
REGS1_k127_2820062_0	335543.Sfum_1736	1.748e-91	310.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,43DN9@68525|delta/epsilon subdivisions,2X25J@28221|Deltaproteobacteria,2MS0P@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
REGS1_k127_2825577_13	1122138.AQUZ01000040_gene6209	3.411e-06	54.0	COG0346@1|root,COG0346@2|Bacteria,2IS4J@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_2825577_9	926569.ANT_28110	1.943e-19	91.0	COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi	200795|Chloroflexi	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
REGS1_k127_2825577_11	502025.Hoch_0529	7.538e-15	76.0	COG3526@1|root,COG3526@2|Bacteria	2|Bacteria	O	Rdx family	-	-	-	ko:K07401	-	-	-	-	ko00000	-	-	-	Rdx
REGS1_k127_2825577_1	926569.ANT_01090	5.533e-153	488.0	COG0180@1|root,COG0180@2|Bacteria,2G6CG@200795|Chloroflexi	200795|Chloroflexi	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
REGS1_k127_2825577_4	309801.trd_1722	4.714e-51	186.0	COG1490@1|root,COG1490@2|Bacteria,2G6P5@200795|Chloroflexi,27YAD@189775|Thermomicrobia	189775|Thermomicrobia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
REGS1_k127_2825577_7	926569.ANT_08190	1.502e-29	119.0	COG1278@1|root,COG1278@2|Bacteria,2G7EU@200795|Chloroflexi	200795|Chloroflexi	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_2825577_5	926569.ANT_09400	3.411e-39	157.0	COG0167@1|root,COG0167@2|Bacteria	2|Bacteria	F	dihydroorotate dehydrogenase activity	-	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
REGS1_k127_2825577_2	926569.ANT_25190	6.545e-143	469.0	COG0493@1|root,COG0493@2|Bacteria,2G6SR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_2825577_8	926569.ANT_25180	9.344e-29	125.0	2FF2N@1|root,3470Y@2|Bacteria,2G9SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2825577_0	926569.ANT_25170	1.445e-164	527.0	COG0612@1|root,COG0612@2|Bacteria,2G5N3@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_2825577_3	926569.ANT_25160	3.503e-136	448.0	COG0612@1|root,COG0612@2|Bacteria,2G68H@200795|Chloroflexi	200795|Chloroflexi	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_2825577_6	926569.ANT_25150	1.845e-31	128.0	COG0736@1|root,COG0736@2|Bacteria,2G73N@200795|Chloroflexi	200795|Chloroflexi	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
REGS1_k127_286645_0	926569.ANT_18180	1.677e-112	374.0	COG1473@1|root,COG1473@2|Bacteria,2G5WT@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase dimerisation domain protein	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_286645_1	702450.CUW_2401	1.642e-08	58.0	COG0551@1|root,COG0551@2|Bacteria,1VBQG@1239|Firmicutes	1239|Firmicutes	L	Protein of unknown function (DUF2726)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726,zf-C4_Topoisom
REGS1_k127_2875960_2	452637.Oter_4523	8.515e-15	75.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,PAP2
REGS1_k127_2875960_1	1229780.BN381_750002	1.27e-19	93.0	2C62F@1|root,335K1@2|Bacteria,2GS5K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2875960_0	1170562.Cal6303_5638	4.733e-80	291.0	COG3464@1|root,COG3464@2|Bacteria,1G6BF@1117|Cyanobacteria	1117|Cyanobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2875960_3	1122915.AUGY01000091_gene5388	2.741e-13	71.0	COG3385@1|root,COG3385@2|Bacteria,1VDW5@1239|Firmicutes,4HMDF@91061|Bacilli,26SXH@186822|Paenibacillaceae	91061|Bacilli	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_4
REGS1_k127_2912751_3	1030157.AFMP01000062_gene3579	1.376e-09	63.0	COG1807@1|root,COG1807@2|Bacteria,1R7IS@1224|Proteobacteria,2U51N@28211|Alphaproteobacteria,2KDIS@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_2912751_2	926569.ANT_01810	1.536e-134	436.0	COG0673@1|root,COG0673@2|Bacteria,2G8FU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_2912751_1	926569.ANT_26630	4.028e-158	503.0	COG0667@1|root,COG0667@2|Bacteria,2G5VT@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_2912751_0	867845.KI911784_gene693	1.927e-169	540.0	COG4214@1|root,COG4214@2|Bacteria,2G8H9@200795|Chloroflexi,376ZS@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
REGS1_k127_2913118_2	204669.Acid345_1359	4.142e-20	93.0	COG3250@1|root,COG3250@2|Bacteria,3Y2PR@57723|Acidobacteria,2JIC7@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolases family 2	-	-	3.2.1.165	ko:K15855	ko00520,ko01100,map00520,map01100	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
REGS1_k127_2913118_3	314278.NB231_06626	5.398e-09	60.0	COG3385@1|root,COG3385@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	Dimer_Tnp_Tn5
REGS1_k127_2913118_0	1255043.TVNIR_2321	1.718e-123	422.0	COG3385@1|root,COG3385@2|Bacteria,1MXYG@1224|Proteobacteria,1S0CA@1236|Gammaproteobacteria,1WXQT@135613|Chromatiales	135613|Chromatiales	L	Transposase IS4 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DUF4338,Dimer_Tnp_Tn5,Tnp_DNA_bind
REGS1_k127_2913118_1	1267535.KB906767_gene5008	2.716e-62	226.0	COG4447@1|root,COG4447@2|Bacteria,3Y2MX@57723|Acidobacteria,2JMA6@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2927437_3	926569.ANT_30160	1.329e-60	210.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_2927437_1	290397.Adeh_2106	1.334e-115	381.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7V@28221|Deltaproteobacteria,2Z1U0@29|Myxococcales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
REGS1_k127_2927437_4	1121448.DGI_0755	0.0002028	49.0	COG1366@1|root,COG1366@2|Bacteria,1N7D9@1224|Proteobacteria,42V1I@68525|delta/epsilon subdivisions,2WRH0@28221|Deltaproteobacteria,2MD3V@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS
REGS1_k127_2927437_2	15368.BRADI1G03250.2	5.727e-97	334.0	COG3511@1|root,2QPJ0@2759|Eukaryota,37HUZ@33090|Viridiplantae,3GH2N@35493|Streptophyta,3KW8G@4447|Liliopsida,3IC9G@38820|Poales	35493|Streptophyta	M	Phosphoesterase family	-	GO:0003674,GO:0003824,GO:0003993,GO:0004620,GO:0004629,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009395,GO:0009405,GO:0009987,GO:0016042,GO:0016298,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044403,GO:0044419,GO:0046434,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:1901575	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
REGS1_k127_2927437_0	926569.ANT_00880	4.461e-203	653.0	COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
REGS1_k127_296660_3	926569.ANT_13170	4.918e-10	69.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_296660_0	926569.ANT_00970	1.067e-196	624.0	COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi	200795|Chloroflexi	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI
REGS1_k127_296660_1	247490.KSU1_C1426	1.541e-92	315.0	COG0042@1|root,COG0042@2|Bacteria,2IYI5@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
REGS1_k127_296660_2	251229.Chro_1451	1.959e-72	248.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,3VIV0@52604|Pleurocapsales	1117|Cyanobacteria	KOT	Response regulator receiver domain	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Response_reg
REGS1_k127_2983730_0	1254432.SCE1572_34585	9.12e-16	89.0	COG3547@1|root,COG3547@2|Bacteria	2|Bacteria	L	Transposase (IS116 IS110 IS902 family)	tnp3510a	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_3014590_2	485913.Krac_9360	1.956e-63	221.0	COG1071@1|root,COG1071@2|Bacteria,2G7RR@200795|Chloroflexi	200795|Chloroflexi	C	PFAM dehydrogenase E1 component	-	-	-	ko:K21416	-	-	-	-	ko00000,ko01000	-	-	-	E1_dh
REGS1_k127_3014590_0	485913.Krac_9361	2.442e-119	392.0	COG2084@1|root,COG2084@2|Bacteria,2G8RG@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 6-phosphogluconate dehydrogenase NAD-binding	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
REGS1_k127_3014590_1	1382306.JNIM01000001_gene2430	4.978e-69	243.0	COG2186@1|root,COG2186@2|Bacteria,2G959@200795|Chloroflexi	200795|Chloroflexi	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
REGS1_k127_3029898_8	671143.DAMO_0966	9.03e-136	442.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2NPE1@2323|unclassified Bacteria	2|Bacteria	S	Peptidase family M50	spoIVFB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K06212,ko:K06402	-	-	-	-	ko00000,ko01000,ko01002,ko02000	1.A.16.1.1,1.A.16.1.3	-	-	CBS,Form_Nir_trans,Peptidase_M50
REGS1_k127_3029898_17	1206732.BAGD01000032_gene983	2.539e-33	134.0	COG3576@1|root,COG3576@2|Bacteria,2I3R7@201174|Actinobacteria,4G1T9@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
REGS1_k127_3029898_6	1163617.SCD_n02069	4.411e-142	461.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
REGS1_k127_3029898_5	697282.Mettu_0616	4.167e-144	470.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
REGS1_k127_3029898_13	1250232.JQNJ01000001_gene172	2.464e-63	224.0	COG0053@1|root,COG0053@2|Bacteria,4NJRM@976|Bacteroidetes,1HXI5@117743|Flavobacteriia	976|Bacteroidetes	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
REGS1_k127_3029898_18	1536775.H70737_09230	2.835e-17	89.0	COG2764@1|root,COG2764@2|Bacteria,1TQ8R@1239|Firmicutes,4HQUZ@91061|Bacilli,26SZ4@186822|Paenibacillaceae	91061|Bacilli	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_3029898_3	926569.ANT_23460	2.38e-166	534.0	COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi	200795|Chloroflexi	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
REGS1_k127_3029898_2	926569.ANT_23450	3.693e-177	563.0	COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi	200795|Chloroflexi	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
REGS1_k127_3029898_15	926569.ANT_23440	2.272e-41	165.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	6.3.2.4	ko:K01921,ko:K03589	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
REGS1_k127_3029898_4	926569.ANT_23430	7.914e-145	468.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
REGS1_k127_3029898_11	926569.ANT_23420	6.332e-101	338.0	COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
REGS1_k127_3029898_9	926569.ANT_23400	1.118e-131	437.0	COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_3029898_10	926569.ANT_23380	1.712e-123	406.0	COG0707@1|root,COG0707@2|Bacteria,2G6EH@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
REGS1_k127_3029898_14	1304880.JAGB01000002_gene1518	6.895e-59	222.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
REGS1_k127_3029898_1	926569.ANT_23360	2.507e-179	572.0	COG0771@1|root,COG0771@2|Bacteria,2G5VE@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
REGS1_k127_3029898_7	926569.ANT_23350	7.164e-140	455.0	COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi	200795|Chloroflexi	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
REGS1_k127_3029898_0	926569.ANT_23340	1.662e-179	576.0	COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi	200795|Chloroflexi	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_3029898_12	926569.ANT_23330	1.257e-69	241.0	COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi	200795|Chloroflexi	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
REGS1_k127_3034445_4	926569.ANT_18580	0.0002712	53.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
REGS1_k127_3034445_0	926569.ANT_26490	2.395e-67	242.0	COG0760@1|root,COG0760@2|Bacteria,2G9A4@200795|Chloroflexi	200795|Chloroflexi	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_3,SurA_N_3
REGS1_k127_3034445_1	1167006.UWK_00322	5.468e-62	218.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria,2MJZ5@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_3034445_3	522306.CAP2UW1_3042	2.414e-14	75.0	COG1639@1|root,COG2114@1|root,COG1639@2|Bacteria,COG2114@2|Bacteria,1RASR@1224|Proteobacteria,2VR0D@28216|Betaproteobacteria	28216|Betaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HDOD
REGS1_k127_3139115_8	926550.CLDAP_11010	1.176e-22	98.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
REGS1_k127_3139115_1	926550.CLDAP_11020	6.82e-155	500.0	COG1173@1|root,COG1173@2|Bacteria,2G841@200795|Chloroflexi	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
REGS1_k127_3139115_4	926550.CLDAP_11030	5.16e-138	448.0	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	appB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_3139115_0	713587.THITH_04495	3.095e-177	589.0	COG0747@1|root,COG3889@1|root,COG0747@2|Bacteria,COG3889@2|Bacteria,1R6EI@1224|Proteobacteria	1224|Proteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_3139115_10	1040989.AWZU01000035_gene1774	1.484e-07	63.0	COG3258@1|root,COG3258@2|Bacteria,1QTYW@1224|Proteobacteria,2TWPT@28211|Alphaproteobacteria,3JVV3@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
REGS1_k127_3139115_6	1009370.ALO_00310	1.085e-81	284.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4H1VB@909932|Negativicutes	909932|Negativicutes	EP	Permease	oppC	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
REGS1_k127_3139115_5	1449126.JQKL01000004_gene567	1.677e-92	316.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,268KP@186813|unclassified Clostridiales	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
REGS1_k127_3139115_7	744872.Spica_2539	1.121e-77	282.0	COG4166@1|root,COG4166@2|Bacteria,2J687@203691|Spirochaetes	203691|Spirochaetes	E	extracellular solute-binding protein, family 5	oppA-1	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
REGS1_k127_3139115_2	489825.LYNGBM3L_13050	1.487e-147	475.0	COG4608@1|root,COG4608@2|Bacteria,1G1Q0@1117|Cyanobacteria,1HA59@1150|Oscillatoriales	1117|Cyanobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
REGS1_k127_3139115_3	926550.CLDAP_11120	5.123e-140	451.0	COG0444@1|root,COG0444@2|Bacteria,2G61B@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
REGS1_k127_3139115_9	349520.PPE_00566	5.508e-19	89.0	COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli,26YAQ@186822|Paenibacillaceae	91061|Bacilli	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
REGS1_k127_3187840_1	1280001.BAOA01000121_gene165	9.429e-07	53.0	COG4948@1|root,COG4948@2|Bacteria,1REK2@1224|Proteobacteria,1S4AA@1236|Gammaproteobacteria,1XYIG@135623|Vibrionales	135623|Vibrionales	M	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
REGS1_k127_3187840_0	391625.PPSIR1_16130	5.031e-150	488.0	COG3039@1|root,COG3039@2|Bacteria,1R70H@1224|Proteobacteria,42Y58@68525|delta/epsilon subdivisions,2WTVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Transposase domain (DUF772)	-	-	-	ko:K07487	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
REGS1_k127_3195866_1	1535287.JP74_00955	8.053e-193	613.0	COG0145@1|root,COG0145@2|Bacteria,1MU2Y@1224|Proteobacteria,2TQZ6@28211|Alphaproteobacteria,3N6U9@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	-	-	3.5.2.14,6.4.1.6	ko:K01473,ko:K10855	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
REGS1_k127_3195866_0	159450.NH14_25260	3.352e-236	742.0	COG0146@1|root,COG0146@2|Bacteria,1QU46@1224|Proteobacteria,2VITF@28216|Betaproteobacteria,1K3N4@119060|Burkholderiaceae	28216|Betaproteobacteria	EQ	Hydantoinase B/oxoprolinase	-	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
REGS1_k127_3195866_2	1134413.ANNK01000133_gene2639	3.311e-79	271.0	COG4126@1|root,COG4126@2|Bacteria,1V0N4@1239|Firmicutes,4HP78@91061|Bacilli,1ZEWI@1386|Bacillus	91061|Bacilli	E	Hydantoin racemase	-	-	5.1.99.3	ko:K16841	ko00230,ko01120,map00230,map01120	-	R03925	RC01027	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
REGS1_k127_3195866_7	926569.ANT_26900	1.656e-06	61.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	4.6.1.13	ko:K01771	ko00562,map00562	-	R03332	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PD40,PI-PLC-X
REGS1_k127_3195866_4	926569.ANT_26890	8.475e-30	126.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	2|Bacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
REGS1_k127_3195866_3	383372.Rcas_1915	2.489e-42	162.0	COG1595@1|root,COG1595@2|Bacteria,2GB53@200795|Chloroflexi,377AG@32061|Chloroflexia	32061|Chloroflexia	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_3195866_6	926569.ANT_26900	2.816e-26	123.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	4.6.1.13	ko:K01771	ko00562,map00562	-	R03332	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	PD40,PI-PLC-X
REGS1_k127_324360_2	1120959.ATXF01000009_gene730	2.373e-29	121.0	COG4747@1|root,COG4747@2|Bacteria,2HTE7@201174|Actinobacteria,4FT5U@85023|Microbacteriaceae	201174|Actinobacteria	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_324360_3	1173025.GEI7407_1711	1.311e-08	61.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1HABM@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Response_reg
REGS1_k127_324360_0	504728.K649_00575	1.377e-133	439.0	COG0477@1|root,COG2814@2|Bacteria,1WJGK@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_324360_1	926569.ANT_06730	2.043e-33	134.0	2E4Y1@1|root,32ZRZ@2|Bacteria,2G9AY@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3258947_1	330214.NIDE0143	5.481e-109	359.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
REGS1_k127_3258947_2	330214.NIDE0143	2.395e-50	181.0	COG3387@1|root,COG3387@2|Bacteria	2|Bacteria	G	glucan 1,4-alpha-glucosidase activity	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glyco_hydro_15
REGS1_k127_3258947_0	330214.NIDE0144	0.0	1074.0	COG0380@1|root,COG0380@2|Bacteria,3J109@40117|Nitrospirae	40117|Nitrospirae	M	Glycosyltransferase family 20	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
REGS1_k127_3258947_3	330214.NIDE0145	1.993e-47	179.0	COG1877@1|root,COG1877@2|Bacteria,3J0UY@40117|Nitrospirae	40117|Nitrospirae	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
REGS1_k127_3311211_0	1487953.JMKF01000036_gene3256	0.0	1186.0	COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,1H7RX@1150|Oscillatoriales	1117|Cyanobacteria	M	Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
REGS1_k127_3311211_1	383372.Rcas_3054	1.827e-70	246.0	COG0229@1|root,COG0229@2|Bacteria,2G78V@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Methionine sulfoxide reductase B	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
REGS1_k127_3335661_3	926569.ANT_22950	8.45e-45	166.0	COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi	200795|Chloroflexi	C	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
REGS1_k127_3335661_2	118163.Ple7327_2167	2.55e-56	219.0	2EWXB@1|root,33Q8Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3335661_1	1293054.HSACCH_00981	5.023e-75	264.0	COG0395@1|root,COG0395@2|Bacteria,1V3Y9@1239|Firmicutes,25C5H@186801|Clostridia,3WBP0@53433|Halanaerobiales	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
REGS1_k127_3335661_0	1293054.HSACCH_00980	2.681e-84	289.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3WBQ6@53433|Halanaerobiales	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
REGS1_k127_3335661_4	1500301.JQMF01000011_gene2464	1.183e-06	53.0	COG1653@1|root,COG1653@2|Bacteria,1MX9J@1224|Proteobacteria,2U3N0@28211|Alphaproteobacteria,4B732@82115|Rhizobiaceae	28211|Alphaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
REGS1_k127_3368069_1	926569.ANT_22190	1.577e-44	170.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
REGS1_k127_3368069_3	926569.ANT_15080	4.252e-26	119.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
REGS1_k127_3368069_2	926569.ANT_22190	6.697e-36	148.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
REGS1_k127_3368069_0	926569.ANT_27910	1.851e-86	291.0	COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
REGS1_k127_338798_6	926569.ANT_14860	3.38e-48	174.0	COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi	200795|Chloroflexi	EK	PFAM Aminotransferase class I and II	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
REGS1_k127_338798_8	1268072.PSAB_21310	1.34e-36	147.0	COG1309@1|root,COG1309@2|Bacteria,1V1R2@1239|Firmicutes,4HPVA@91061|Bacilli,274GN@186822|Paenibacillaceae	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_338798_4	1123368.AUIS01000003_gene1806	3.608e-56	203.0	COG4319@1|root,COG4319@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,LUD_dom,SnoaL_3,SnoaL_4
REGS1_k127_338798_3	1183438.GKIL_0974	2.26e-77	271.0	COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria	1117|Cyanobacteria	C	NADPH quinone reductase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
REGS1_k127_338798_11	1120972.AUMH01000003_gene2931	1.768e-07	60.0	COG1846@1|root,COG1846@2|Bacteria,1VACT@1239|Firmicutes,4HMWN@91061|Bacilli,278HM@186823|Alicyclobacillaceae	91061|Bacilli	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
REGS1_k127_338798_1	765420.OSCT_0044	8.007e-101	342.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,37723@32061|Chloroflexia	32061|Chloroflexia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
REGS1_k127_338798_9	357808.RoseRS_2104	1.848e-35	155.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G93B@200795|Chloroflexi,3764W@32061|Chloroflexia	32061|Chloroflexia	MV	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23
REGS1_k127_338798_2	926550.CLDAP_07700	1.238e-90	311.0	COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_338798_0	765420.OSCT_0041	4.788e-104	347.0	COG1131@1|root,COG1131@2|Bacteria,2G7U7@200795|Chloroflexi,37725@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_338798_5	1122223.KB890701_gene2339	9.268e-56	200.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006996,GO:0007010,GO:0007015,GO:0008092,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044877,GO:0046983,GO:0051015,GO:0051259,GO:0065003,GO:0071840,GO:0097435	6.5.1.1	ko:K01971,ko:K03086,ko:K06867,ko:K06886	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03021,ko03400	-	-	-	Ank,Ank_2,Ank_4,Ank_5
REGS1_k127_338798_7	1144275.COCOR_05767	8.494e-40	163.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_342148_3	643648.Slip_1694	7.49e-40	158.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia,42JYS@68298|Syntrophomonadaceae	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
REGS1_k127_342148_2	926550.CLDAP_18870	1.769e-97	348.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,2G6G7@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
REGS1_k127_342148_0	1089550.ATTH01000001_gene2135	8.228e-147	479.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
REGS1_k127_342148_1	518766.Rmar_1606	5.621e-123	413.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
REGS1_k127_3464221_0	926550.CLDAP_32740	1.632e-245	778.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi	2|Bacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	bisC	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
REGS1_k127_3466929_0	1121405.dsmv_3003	1.151e-278	869.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_3485584_3	1380391.JIAS01000004_gene2960	1.518e-58	209.0	COG0747@1|root,COG0747@2|Bacteria,1MUPE@1224|Proteobacteria,2TS4U@28211|Alphaproteobacteria,2JP86@204441|Rhodospirillales	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_3485584_2	1380391.JIAS01000004_gene2961	1.052e-98	332.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2TSIY@28211|Alphaproteobacteria,2JR5B@204441|Rhodospirillales	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_3485584_1	1380391.JIAS01000004_gene2962	6.604e-99	332.0	COG1173@1|root,COG1173@2|Bacteria,1MU0P@1224|Proteobacteria,2VF9K@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_3485584_0	1380391.JIAS01000004_gene2963	3.1e-169	549.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2TQNH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
REGS1_k127_3490328_4	926569.ANT_20910	1.49e-100	336.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
REGS1_k127_3490328_1	1121468.AUBR01000034_gene1374	2.628e-196	628.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
REGS1_k127_3490328_0	926569.ANT_20890	2.637e-287	893.0	COG0465@1|root,COG0465@2|Bacteria,2G5J3@200795|Chloroflexi	200795|Chloroflexi	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
REGS1_k127_3490328_5	926569.ANT_16430	5.238e-37	145.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_16430|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3490328_6	926569.ANT_16420	1.56e-25	112.0	COG1430@1|root,COG1430@2|Bacteria	2|Bacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
REGS1_k127_3490328_3	926569.ANT_16410	1.904e-114	385.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G901@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
REGS1_k127_3490328_2	926550.CLDAP_11320	5.946e-121	400.0	COG0683@1|root,COG0683@2|Bacteria,2G6Q3@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_3506918_1	330214.NIDE1489	2.693e-75	258.0	COG2197@1|root,COG2197@2|Bacteria,3J12Q@40117|Nitrospirae	40117|Nitrospirae	K	Product type r regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_3506918_2	56780.SYN_01954	5.69e-50	201.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42RUN@68525|delta/epsilon subdivisions,2WNJZ@28221|Deltaproteobacteria,2MR4S@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,HAMP,HATPase_c,HisKA_3,PAS_3,PAS_4,PAS_9
REGS1_k127_3506918_3	926560.KE387027_gene261	5.964e-26	125.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1WMF2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
REGS1_k127_3506918_7	1123277.KB893239_gene1082	0.0002323	46.0	2EFZF@1|root,339RM@2|Bacteria,4NXMV@976|Bacteroidetes,47SRN@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TspO_MBR
REGS1_k127_3506918_0	1499967.BAYZ01000038_gene2261	1.495e-94	314.0	COG0705@1|root,COG0705@2|Bacteria,2NPGI@2323|unclassified Bacteria	2|Bacteria	S	(Rhomboid) family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
REGS1_k127_3506918_6	1246626.BleG1_3504	2.095e-06	50.0	2EFZF@1|root,339RM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3506918_5	977880.RALTA_B0382	7.291e-17	82.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,1K9H1@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
REGS1_k127_3506918_4	1254432.SCE1572_00115	1.065e-18	90.0	COG0776@1|root,COG0776@2|Bacteria,1N6FS@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the bacterial histone-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
REGS1_k127_3507039_1	1121405.dsmv_2307	4.191e-217	683.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,2MJ57@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_3507039_4	118166.JH976538_gene5111	2.828e-50	184.0	2AWZQ@1|root,31NXM@2|Bacteria,1G6ZZ@1117|Cyanobacteria,1HBW7@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3507039_2	485913.Krac_2299	2.573e-98	337.0	COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
REGS1_k127_3507039_6	357808.RoseRS_4245	0.0007654	48.0	COG1787@1|root,COG1787@2|Bacteria,2G7E4@200795|Chloroflexi,3761Z@32061|Chloroflexia	32061|Chloroflexia	V	PFAM restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat,SH3_3
REGS1_k127_3507039_0	926569.ANT_31720	3.71e-314	966.0	COG2987@1|root,COG2987@2|Bacteria,2G5PQ@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
REGS1_k127_3507039_3	926569.ANT_00140	7.893e-52	186.0	COG1959@1|root,COG1959@2|Bacteria,2G8ZH@200795|Chloroflexi	200795|Chloroflexi	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
REGS1_k127_3507039_5	926569.ANT_13170	1.628e-39	154.0	COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi	200795|Chloroflexi	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3512849_11	324602.Caur_2859	1.985e-25	110.0	COG1893@1|root,COG1893@2|Bacteria	2|Bacteria	H	2-dehydropantoate 2-reductase activity	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
REGS1_k127_3512849_9	926569.ANT_26960	2.822e-31	134.0	2EH75@1|root,33AYZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3512849_8	525904.Tter_0301	1.63e-41	171.0	COG2203@1|root,COG3284@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3284@2|Bacteria,COG4585@2|Bacteria,2NPMD@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07777,ko:K19661,ko:K21405	ko02020,map02020	M00478,M00772	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03000	-	-	-	GAF,GAF_2,HATPase_c,HisKA,HisKA_3,Lactamase_B_2,PAS,PAS_4,PAS_9
REGS1_k127_3512849_5	485913.Krac_6669	2.909e-69	242.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_3512849_14	1123020.AUIE01000002_gene1380	1.92e-13	81.0	COG0457@1|root,COG0457@2|Bacteria,1MX2U@1224|Proteobacteria,1RPD2@1236|Gammaproteobacteria,1YFCT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,HEAT_2,Paired_CXXCH_1,TPR_16,TPR_19,TPR_20,TPR_8
REGS1_k127_3512849_7	62928.azo1947	1.473e-54	200.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,2KXUS@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	ko:K18362	ko00360,map00360	-	R07222,R07294	RC00004,RC01844,RC01903	ko00000,ko00001	-	-	-	-
REGS1_k127_3512849_6	1121920.AUAU01000012_gene2648	3.303e-57	216.0	COG5557@1|root,COG5557@2|Bacteria,3Y3RF@57723|Acidobacteria	57723|Acidobacteria	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
REGS1_k127_3512849_0	926569.ANT_21940	6.094e-190	608.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrom_c3_2
REGS1_k127_3512849_15	575540.Isop_0042	2.221e-07	64.0	COG2319@1|root,COG2319@2|Bacteria,2IY5Q@203682|Planctomycetes	203682|Planctomycetes	M	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,PSCyt1,PSCyt2,PSD1,WD40
REGS1_k127_3512849_13	1384056.N787_10295	4.198e-18	99.0	COG0607@1|root,COG2010@1|root,COG0607@2|Bacteria,COG2010@2|Bacteria,1R6Z0@1224|Proteobacteria,1RXZ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,Rhodanese
REGS1_k127_3512849_12	929712.KI912613_gene1096	6.927e-25	121.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,2HDYV@201174|Actinobacteria,4CQSB@84995|Rubrobacteria	84995|Rubrobacteria	C	Cytochrome b subunit of the bc	-	-	-	ko:K03888	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_CBB3
REGS1_k127_3512849_4	330214.NIDE3889	9.58e-72	248.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
REGS1_k127_3512849_10	491915.Aflv_1113	2.976e-26	114.0	COG0723@1|root,COG0723@2|Bacteria,1TQUH@1239|Firmicutes,4HBX1@91061|Bacilli,21WF9@150247|Anoxybacillus	91061|Bacilli	C	Rieske [2Fe-2S] domain	qcrA	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	CytB6-F_Fe-S,Rieske
REGS1_k127_3512849_2	926569.ANT_26970	9.739e-113	377.0	COG2010@1|root,COG2864@1|root,COG2010@2|Bacteria,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB,PSCyt1
REGS1_k127_3512849_3	926569.ANT_26980	1.495e-112	376.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrom_c3_2,Paired_CXXCH_1
REGS1_k127_3512849_1	926569.ANT_21930	3.878e-154	498.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.81,3.2.1.97	ko:K01219,ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	Big_2,CBM_6,Cytochrome_C7,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,WxL
REGS1_k127_3534932_7	1173028.ANKO01000124_gene2870	0.0003718	44.0	COG2026@1|root,COG2026@2|Bacteria,1GAIF@1117|Cyanobacteria	1117|Cyanobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
REGS1_k127_3534932_6	383372.Rcas_1470	6.275e-07	54.0	293XT@1|root,2ZRCU@2|Bacteria	2|Bacteria	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_3534932_0	1040989.AWZU01000028_gene3001	7.586e-94	316.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,2TTSG@28211|Alphaproteobacteria,3JRZP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
REGS1_k127_3534932_5	107636.JQNK01000009_gene1742	1.015e-40	156.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2UBP8@28211|Alphaproteobacteria,37053@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Haem-degrading	-	-	-	ko:K11477	-	-	-	-	ko00000	-	-	-	Haem_degrading
REGS1_k127_3534932_4	96561.Dole_1205	1.848e-51	186.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,42T2P@68525|delta/epsilon subdivisions,2WPQ3@28221|Deltaproteobacteria,2MKI3@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
REGS1_k127_3534932_1	886293.Sinac_3443	6.186e-70	239.0	COG0225@1|root,COG0225@2|Bacteria,2IZ67@203682|Planctomycetes	203682|Planctomycetes	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
REGS1_k127_3534932_3	1192034.CAP_7743	4.863e-52	193.0	COG2050@1|root,COG2050@2|Bacteria,1RGVD@1224|Proteobacteria	1224|Proteobacteria	Q	protein possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_3534932_2	1123320.KB889683_gene2060	3.375e-68	237.0	COG2346@1|root,COG3369@1|root,COG3592@1|root,COG2346@2|Bacteria,COG3369@2|Bacteria,COG3592@2|Bacteria,2I95U@201174|Actinobacteria	201174|Actinobacteria	S	Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin,Fer4_19,zf-CDGSH
REGS1_k127_3540265_0	1382306.JNIM01000001_gene329	2.966e-91	306.0	COG0183@1|root,COG0183@2|Bacteria,2G5YW@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_3540265_3	1382306.JNIM01000001_gene3604	1.609e-43	175.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	nanA	GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,Gram_pos_anchor,Sialidase,YSIRK_signal
REGS1_k127_3540265_1	926569.ANT_03090	7.5e-90	308.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
REGS1_k127_3540265_2	926569.ANT_17990	2.453e-79	271.0	COG2345@1|root,COG2345@2|Bacteria,2G79S@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein, ArsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
REGS1_k127_3540265_4	926569.ANT_18000	1.845e-30	126.0	COG2151@1|root,COG2151@2|Bacteria,2G9UF@200795|Chloroflexi	200795|Chloroflexi	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
REGS1_k127_3575165_1	1121918.ARWE01000001_gene3102	1.822e-186	592.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42PNI@68525|delta/epsilon subdivisions,2WJNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
REGS1_k127_3575165_3	1304885.AUEY01000013_gene3126	1.894e-64	233.0	COG0589@1|root,COG0589@2|Bacteria,1QR0W@1224|Proteobacteria,42SGI@68525|delta/epsilon subdivisions,2WPQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_3575165_2	481448.Minf_2378	5.752e-84	294.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria,46WTS@74201|Verrucomicrobia,37G3H@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin,VIT1
REGS1_k127_3575165_0	926569.ANT_19970	1.084e-266	829.0	COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi	200795|Chloroflexi	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
REGS1_k127_3582242_6	383372.Rcas_1228	5.117e-07	56.0	COG2197@1|root,COG2197@2|Bacteria,2G73R@200795|Chloroflexi,377PI@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
REGS1_k127_3582242_2	1128421.JAGA01000002_gene1676	3.416e-77	269.0	COG0265@1|root,COG0265@2|Bacteria,2NQV1@2323|unclassified Bacteria	2|Bacteria	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_3582242_5	926569.ANT_16590	1.715e-37	145.0	29ATW@1|root,2ZXTA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3582242_3	926569.ANT_16600	1.775e-76	276.0	COG0544@1|root,COG0544@2|Bacteria,2G6GA@200795|Chloroflexi	200795|Chloroflexi	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
REGS1_k127_3582242_0	926569.ANT_16610	7.107e-94	314.0	COG0740@1|root,COG0740@2|Bacteria,2G6BN@200795|Chloroflexi	200795|Chloroflexi	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
REGS1_k127_3582242_1	309801.trd_A0702	2.122e-91	311.0	COG3342@1|root,COG3342@2|Bacteria,2G663@200795|Chloroflexi,27Y6W@189775|Thermomicrobia	189775|Thermomicrobia	S	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1028,PG_binding_2
REGS1_k127_3582242_4	926569.ANT_16620	2.884e-65	230.0	COG0647@1|root,COG0647@2|Bacteria,2G6G5@200795|Chloroflexi	200795|Chloroflexi	G	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	3.1.3.41	ko:K01101	ko00627,ko01120,map00627,map01120	-	R03024	RC00151	ko00000,ko00001,ko01000	-	-	-	Hydrolase_6,Hydrolase_like
REGS1_k127_3586579_1	344747.PM8797T_12993	1.402e-36	146.0	COG1402@1|root,COG1402@2|Bacteria	2|Bacteria	I	creatininase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
REGS1_k127_3586579_0	344747.PM8797T_30581	1.434e-119	401.0	COG4948@1|root,COG4948@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.1.6	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	M00552	R03033	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4433,MR_MLE_C
REGS1_k127_3586579_2	1380391.JIAS01000005_gene2424	1.406e-07	57.0	28Q55@1|root,2ZCN6@2|Bacteria,1P7CW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3595428_0	247490.KSU1_C0704	5.457e-144	464.0	COG0841@1|root,COG0841@2|Bacteria,2IY6W@203682|Planctomycetes	203682|Planctomycetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07788	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2	-	-	ACR_tran
REGS1_k127_3595428_5	234267.Acid_4496	2.489e-07	58.0	COG2318@1|root,COG2318@2|Bacteria,3Y8UQ@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
REGS1_k127_3595428_1	1173028.ANKO01000102_gene5411	5.563e-80	275.0	COG1656@1|root,COG1656@2|Bacteria,1G344@1117|Cyanobacteria,1HAHV@1150|Oscillatoriales	1117|Cyanobacteria	S	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
REGS1_k127_3595428_3	234267.Acid_5054	2.49e-41	157.0	COG2318@1|root,COG2318@2|Bacteria,3Y579@57723|Acidobacteria	57723|Acidobacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
REGS1_k127_3595428_2	204669.Acid345_1820	3.43e-78	267.0	COG0549@1|root,COG0549@2|Bacteria,3Y7CP@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
REGS1_k127_3595428_4	204669.Acid345_1820	1.562e-31	128.0	COG0549@1|root,COG0549@2|Bacteria,3Y7CP@57723|Acidobacteria	57723|Acidobacteria	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
REGS1_k127_3598578_14	926569.ANT_18350	1.415e-64	233.0	COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_3598578_12	1089550.ATTH01000001_gene925	1.199e-84	293.0	COG0491@1|root,COG0491@2|Bacteria,4NHXR@976|Bacteroidetes,1FJDJ@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.5.2.6	ko:K17837	ko01501,map01501	-	R06363	RC01499	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
REGS1_k127_3598578_4	926569.ANT_18090	1.553e-152	488.0	COG0078@1|root,COG0078@2|Bacteria,2G5Z9@200795|Chloroflexi	200795|Chloroflexi	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_3598578_2	926569.ANT_18100	6.267e-208	651.0	COG4992@1|root,COG4992@2|Bacteria	2|Bacteria	E	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	rocD	GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.6.1.11,2.6.1.13,2.6.1.17	ko:K00819,ko:K00821	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00667,R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iYO844.BSU40340	Aminotran_3
REGS1_k127_3598578_10	1278073.MYSTI_03806	4.466e-97	329.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,42MSF@68525|delta/epsilon subdivisions,2WKJ5@28221|Deltaproteobacteria,2YU7F@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1099	AlaDh_PNT_C,AlaDh_PNT_N
REGS1_k127_3598578_3	1232410.KI421419_gene2455	8.546e-203	641.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,43UGV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
REGS1_k127_3598578_8	926569.ANT_18110	1.724e-138	460.0	COG0469@1|root,COG0469@2|Bacteria,2G5YE@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
REGS1_k127_3598578_17	696369.KI912183_gene1317	2.75e-54	201.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,249RU@186801|Clostridia,264YK@186807|Peptococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_3598578_27	1121927.GOHSU_04_00230	5.922e-12	70.0	COG1983@1|root,COG1983@2|Bacteria,2GQG0@201174|Actinobacteria,4GF7U@85026|Gordoniaceae	201174|Actinobacteria	KT	PspC domain	pspC1	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
REGS1_k127_3598578_30	926550.CLDAP_35480	5.224e-06	55.0	COG3103@1|root,COG3693@1|root,COG3103@2|Bacteria,COG3693@2|Bacteria,COG4991@2|Bacteria,2GBGU@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase,Glyco_hydro_42
REGS1_k127_3598578_32	643648.Slip_0268	0.0007277	50.0	COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,COG4991@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,42K1M@68298|Syntrophomonadaceae	186801|Clostridia	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,Cu_amine_oxidN1,SH3_3
REGS1_k127_3598578_20	247490.KSU1_C0604	5.672e-36	142.0	COG1186@1|root,COG1186@2|Bacteria,2J05G@203682|Planctomycetes	203682|Planctomycetes	J	chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
REGS1_k127_3598578_7	926569.ANT_18140	1.402e-143	463.0	COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi	200795|Chloroflexi	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
REGS1_k127_3598578_1	926569.ANT_18150	2.842e-245	773.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2G69H@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
REGS1_k127_3598578_15	926569.ANT_18160	2.217e-63	224.0	COG2186@1|root,COG2186@2|Bacteria,2G8XU@200795|Chloroflexi	200795|Chloroflexi	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD
REGS1_k127_3598578_6	926569.ANT_16400	2.244e-146	480.0	2EYH8@1|root,33RR4@2|Bacteria,2G7WE@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3598578_19	926569.ANT_16390	9.212e-40	156.0	2FJCP@1|root,34B2I@2|Bacteria,2G94J@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3598578_29	1173264.KI913949_gene2492	3.315e-07	63.0	COG4632@1|root,COG4632@2|Bacteria,1G20S@1117|Cyanobacteria,1H89D@1150|Oscillatoriales	1117|Cyanobacteria	G	periplasmic protein (DUF2233)	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
REGS1_k127_3598578_31	208444.JNYY01000016_gene952	8.175e-05	54.0	COG3757@1|root,COG3757@2|Bacteria,2GKS0@201174|Actinobacteria,4DX99@85010|Pseudonocardiales	201174|Actinobacteria	M	lysozyme	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25
REGS1_k127_3598578_26	264732.Moth_1271	1.978e-17	92.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,24S59@186801|Clostridia,42J2N@68295|Thermoanaerobacterales	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
REGS1_k127_3598578_22	926569.ANT_31070	1.038e-31	132.0	COG0551@1|root,COG0551@2|Bacteria	2|Bacteria	L	DNA topological change	-	-	-	-	-	-	-	-	-	-	-	-	DUF2726,zf-C4_Topoisom
REGS1_k127_3598578_16	1521187.JPIM01000016_gene3688	3.635e-63	222.0	COG2077@1|root,COG2077@2|Bacteria,2G8IQ@200795|Chloroflexi	200795|Chloroflexi	O	Redoxin	-	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	-
REGS1_k127_3598578_24	926569.ANT_18300	6.782e-27	114.0	COG0071@1|root,COG0071@2|Bacteria,2G7BB@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
REGS1_k127_3598578_0	926569.ANT_18310	0.0	1137.0	COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi	200795|Chloroflexi	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_3598578_25	926569.ANT_18320	2.623e-20	94.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K03413,ko:K07719	ko02020,ko02030,map02020,map02030	M00506,M00518	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HATPase_c,Response_reg,YcbB
REGS1_k127_3598578_23	1122221.JHVI01000011_gene1006	1.232e-27	117.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	ypeA	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
REGS1_k127_3598578_18	926569.ANT_18330	3.724e-54	196.0	COG0521@1|root,COG0521@2|Bacteria,2G7HV@200795|Chloroflexi	200795|Chloroflexi	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
REGS1_k127_3598578_13	926569.ANT_20860	3.496e-74	255.0	COG0231@1|root,COG0231@2|Bacteria,2G6PY@200795|Chloroflexi	200795|Chloroflexi	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
REGS1_k127_3598578_11	926569.ANT_20880	3.129e-92	317.0	COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_3598578_5	1341151.ASZU01000004_gene111	4.293e-148	479.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,27B4D@186824|Thermoactinomycetaceae	91061|Bacilli	IQ	Beta-ketoacyl synthase, C-terminal domain	fabF3	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_3598578_9	926550.CLDAP_06710	8.97e-116	383.0	COG0332@1|root,COG0332@2|Bacteria,2G630@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_3614472_0	926569.ANT_00200	2.632e-120	394.0	COG2133@1|root,COG2133@2|Bacteria,2G62S@200795|Chloroflexi	200795|Chloroflexi	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	GSDH
REGS1_k127_3614472_2	1121468.AUBR01000024_gene3019	6.4e-60	216.0	COG3842@1|root,COG3842@2|Bacteria,1V5RM@1239|Firmicutes,24IMD@186801|Clostridia,42GAV@68295|Thermoanaerobacterales	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.55	ko:K06857	ko02010,map02010	M00186	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran,TOBE_2
REGS1_k127_3614472_1	671143.DAMO_1144	1.095e-84	286.0	COG4662@1|root,COG4662@2|Bacteria,2NPF5@2323|unclassified Bacteria	2|Bacteria	H	Binding-protein-dependent transport system inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
REGS1_k127_3614472_3	370438.PTH_0602	1.088e-38	147.0	COG2998@1|root,COG2998@2|Bacteria,1TQA9@1239|Firmicutes,249EZ@186801|Clostridia,2605W@186807|Peptococcaceae	186801|Clostridia	H	PBP superfamily domain	tupA	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
REGS1_k127_3627798_0	1174684.EBMC1_01280	3.018e-144	467.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1MVH7@1224|Proteobacteria,2TRNA@28211|Alphaproteobacteria,2K05E@204457|Sphingomonadales	204457|Sphingomonadales	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
REGS1_k127_3627798_2	391595.RLO149_c028220	2.698e-19	94.0	2E8HV@1|root,332VX@2|Bacteria,1NB2K@1224|Proteobacteria,2UFU2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3627798_1	189753.AXAS01000029_gene6895	1.087e-90	315.0	COG5362@1|root,COG5410@1|root,COG5362@2|Bacteria,COG5410@2|Bacteria,1NKZK@1224|Proteobacteria,2U0EG@28211|Alphaproteobacteria,3JXF7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Terminase RNaseH-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_6C
REGS1_k127_3628910_3	1123487.KB892834_gene2720	7.978e-33	130.0	COG1122@1|root,COG1122@2|Bacteria,1QWP9@1224|Proteobacteria	1224|Proteobacteria	P	Pfam ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,DUF3744
REGS1_k127_3628910_2	525904.Tter_0883	8.325e-59	214.0	COG0619@1|root,COG0619@2|Bacteria,2NRVG@2323|unclassified Bacteria	2|Bacteria	P	PFAM Cobalt transport protein	cbiQ	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
REGS1_k127_3628910_1	1122963.AUHB01000016_gene4361	3.191e-94	322.0	COG0310@1|root,COG0310@2|Bacteria,1NTQK@1224|Proteobacteria,2U0RQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
REGS1_k127_3628910_6	926569.ANT_12680	4.455e-05	53.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
REGS1_k127_3628910_7	926569.ANT_12680	6.939e-05	52.0	COG0735@1|root,COG0735@2|Bacteria,2G723@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
REGS1_k127_3628910_5	1233950.IW22_17980	1.945e-06	59.0	2DBYB@1|root,2ZBUC@2|Bacteria,4NRE9@976|Bacteroidetes,1I3UH@117743|Flavobacteriia,3ZR1V@59732|Chryseobacterium	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3628910_0	926569.ANT_00850	1.222e-226	709.0	COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi	200795|Chloroflexi	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_3628910_4	314282.PCNPT3_12835	2.015e-32	143.0	28MUJ@1|root,30IRJ@2|Bacteria,1QJ4Q@1224|Proteobacteria,1TH25@1236|Gammaproteobacteria,2QJ7S@267894|Psychromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3628910_8	1457393.AZ09_09900	0.0001659	47.0	COG2939@1|root,COG2939@2|Bacteria,1MW05@1224|Proteobacteria,2TS7R@28211|Alphaproteobacteria,2JVR3@204441|Rhodospirillales	204441|Rhodospirillales	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
REGS1_k127_3639605_1	351160.RCIX51	1.205e-91	307.0	COG1131@1|root,arCOG00194@2157|Archaea,2XT0T@28890|Euryarchaeota	28890|Euryarchaeota	E	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_3639605_0	42256.RradSPS_0358	2.878e-135	464.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
REGS1_k127_3652936_0	272134.KB731324_gene3814	3.793e-88	304.0	COG5433@1|root,COG5433@2|Bacteria,1G0VN@1117|Cyanobacteria,1H992@1150|Oscillatoriales	1117|Cyanobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
REGS1_k127_3652936_1	398578.Daci_2444	1.884e-34	138.0	COG3181@1|root,COG3181@2|Bacteria,1MU58@1224|Proteobacteria,2VKCY@28216|Betaproteobacteria,4A9R1@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	TctC
REGS1_k127_3661989_4	1403819.BATR01000181_gene6068	7.11e-85	289.0	COG1442@1|root,COG1442@2|Bacteria,46VJK@74201|Verrucomicrobia	74201|Verrucomicrobia	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3661989_1	1123072.AUDH01000008_gene194	5.818e-115	382.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2TRIQ@28211|Alphaproteobacteria,2JQZ9@204441|Rhodospirillales	204441|Rhodospirillales	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_3661989_0	326427.Cagg_2150	3.67e-163	518.0	COG0451@1|root,COG0451@2|Bacteria,2G7KN@200795|Chloroflexi,375A6@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_3661989_7	1304877.KI519400_gene374	1.797e-47	180.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Methyltransf_11,Methyltransf_25,Methyltransf_31
REGS1_k127_3661989_2	189753.AXAS01000005_gene649	2.776e-95	326.0	COG4641@1|root,COG4641@2|Bacteria,1R62R@1224|Proteobacteria,2TVHD@28211|Alphaproteobacteria,3JWFP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
REGS1_k127_3661989_3	755178.Cyan10605_1198	5.431e-94	332.0	COG0438@1|root,COG0463@1|root,COG0438@2|Bacteria,COG0463@2|Bacteria,1G2T9@1117|Cyanobacteria	1117|Cyanobacteria	M	glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_3661989_8	643867.Ftrac_2216	2.789e-36	157.0	COG2230@1|root,COG2230@2|Bacteria,4PM0J@976|Bacteroidetes	976|Bacteroidetes	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
REGS1_k127_3661989_6	329726.AM1_1908	2.542e-58	211.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
REGS1_k127_3661989_5	525904.Tter_2802	4.217e-75	263.0	COG1134@1|root,COG1134@2|Bacteria,2NP4S@2323|unclassified Bacteria	2|Bacteria	GM	ATPases associated with a variety of cellular activities	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
REGS1_k127_3675878_2	358823.DF19_10230	7.95e-12	74.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_3675878_0	383372.Rcas_3097	1.534e-38	163.0	COG0297@1|root,COG0297@2|Bacteria,2GBMD@200795|Chloroflexi,37794@32061|Chloroflexia	32061|Chloroflexia	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_3675878_1	373994.Riv7116_5679	2.39e-21	102.0	COG1216@1|root,COG1216@2|Bacteria,1G2ZC@1117|Cyanobacteria,1HKUT@1161|Nostocales	1117|Cyanobacteria	S	glycosyl transferase family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_3688949_3	1410653.JHVC01000003_gene3897	0.0002177	44.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
REGS1_k127_3688949_0	926569.ANT_18650	3.797e-126	412.0	COG1131@1|root,COG1131@2|Bacteria,2G5PC@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
REGS1_k127_3688949_2	926569.ANT_18660	5.889e-71	247.0	COG1277@1|root,COG1277@2|Bacteria	2|Bacteria	-	-	yxlG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
REGS1_k127_3688949_1	926569.ANT_18670	6.261e-125	419.0	COG3225@1|root,COG3225@2|Bacteria	2|Bacteria	-	-	gldG	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
REGS1_k127_3699213_1	926569.ANT_11330	1.266e-45	170.0	COG2606@1|root,COG2606@2|Bacteria,2G73X@200795|Chloroflexi	200795|Chloroflexi	J	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
REGS1_k127_3699213_0	926550.CLDAP_38680	2.436e-228	715.0	COG1690@1|root,COG1690@2|Bacteria,2G5NT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
REGS1_k127_3699213_2	926550.CLDAP_38690	2.813e-39	150.0	COG1371@1|root,COG1371@2|Bacteria,2G7BQ@200795|Chloroflexi	200795|Chloroflexi	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
REGS1_k127_3699213_3	926569.ANT_28330	1.358e-22	106.0	COG0608@1|root,COG0608@2|Bacteria,2G7JK@200795|Chloroflexi	200795|Chloroflexi	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
REGS1_k127_3706254_8	196162.Noca_1631	6.291e-34	132.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4DV65@85009|Propionibacteriales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_3706254_6	926569.ANT_01230	3.383e-73	254.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_3706254_1	926569.ANT_01220	4.089e-247	776.0	COG1001@1|root,COG1001@2|Bacteria,2G64P@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
REGS1_k127_3706254_2	926569.ANT_01210	2.702e-216	679.0	COG0402@1|root,COG0402@2|Bacteria,2G5X1@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
REGS1_k127_3706254_11	269799.Gmet_2656	0.000842	46.0	2EG51@1|root,339WY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3706254_0	402777.KB235903_gene1681	1.71e-252	794.0	COG1506@1|root,COG1506@2|Bacteria,1G200@1117|Cyanobacteria,1H8T3@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Prolyl oligopeptidase family	dap2	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
REGS1_k127_3706254_4	926550.CLDAP_35510	6.438e-144	467.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	200795|Chloroflexi	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
REGS1_k127_3706254_9	945713.IALB_1306	1.509e-05	56.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
REGS1_k127_3706254_5	926569.ANT_02380	5.485e-117	383.0	COG0190@1|root,COG0190@2|Bacteria,2G6BA@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
REGS1_k127_3706254_3	926569.ANT_16230	3.961e-153	496.0	COG0621@1|root,COG0621@2|Bacteria,2G5UI@200795|Chloroflexi	200795|Chloroflexi	J	modification enzyme, MiaB family	-	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
REGS1_k127_3713443_16	926569.ANT_10350	8.951e-50	180.0	COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
REGS1_k127_3713443_17	243274.THEMA_07045	2.388e-48	177.0	COG0102@1|root,COG0102@2|Bacteria,2GD15@200918|Thermotogae	200918|Thermotogae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
REGS1_k127_3713443_8	926569.ANT_10330	1.812e-70	246.0	COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi	200795|Chloroflexi	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
REGS1_k127_3713443_18	926569.ANT_10320	3.581e-46	171.0	COG0203@1|root,COG0203@2|Bacteria,2G79I@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
REGS1_k127_3713443_1	926569.ANT_10310	1.846e-162	515.0	COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
REGS1_k127_3713443_4	926569.ANT_10300	5.072e-88	295.0	COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
REGS1_k127_3713443_11	926569.ANT_10290	1.88e-60	211.0	COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi	200795|Chloroflexi	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
REGS1_k127_3713443_14	926569.ANT_10280	7.829e-59	205.0	COG0099@1|root,COG0099@2|Bacteria,2G6PF@200795|Chloroflexi	200795|Chloroflexi	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
REGS1_k127_3713443_25	926569.ANT_10270	5.695e-13	70.0	COG0257@1|root,COG0257@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
REGS1_k127_3713443_2	926569.ANT_10260	2.242e-107	353.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi	200795|Chloroflexi	J	TIGRFAM methionine aminopeptidase, type I	-	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
REGS1_k127_3713443_6	926569.ANT_10250	1.868e-77	265.0	COG0563@1|root,COG0563@2|Bacteria,2G6GP@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
REGS1_k127_3713443_0	926569.ANT_10240	1.052e-165	532.0	COG0201@1|root,COG0201@2|Bacteria,2G5X4@200795|Chloroflexi	200795|Chloroflexi	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
REGS1_k127_3713443_15	926569.ANT_10230	9.612e-56	198.0	COG0200@1|root,COG0200@2|Bacteria,2G6XY@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
REGS1_k127_3713443_24	926569.ANT_10220	1.71e-16	82.0	COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L30	rpmD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
REGS1_k127_3713443_7	926569.ANT_10210	4.674e-71	247.0	COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi	200795|Chloroflexi	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
REGS1_k127_3713443_19	926569.ANT_10200	9.248e-43	160.0	COG0256@1|root,COG0256@2|Bacteria,2G6Y4@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
REGS1_k127_3713443_9	926569.ANT_10190	2.092e-70	243.0	COG0097@1|root,COG0097@2|Bacteria,2G6HZ@200795|Chloroflexi	200795|Chloroflexi	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
REGS1_k127_3713443_12	926569.ANT_10180	3.722e-59	210.0	COG0096@1|root,COG0096@2|Bacteria,2G6XS@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
REGS1_k127_3713443_22	926569.ANT_10170	3.433e-26	108.0	COG0199@1|root,COG0199@2|Bacteria,2G74J@200795|Chloroflexi	200795|Chloroflexi	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
REGS1_k127_3713443_5	926569.ANT_10160	8.88e-84	282.0	COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi	200795|Chloroflexi	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
REGS1_k127_3713443_20	926569.ANT_10150	1.123e-40	155.0	COG0198@1|root,COG0198@2|Bacteria,2G750@200795|Chloroflexi	200795|Chloroflexi	J	One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplX	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
REGS1_k127_3713443_13	926569.ANT_10140	4.529e-59	208.0	COG0093@1|root,COG0093@2|Bacteria,2G6MZ@200795|Chloroflexi	200795|Chloroflexi	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
REGS1_k127_3713443_23	926569.ANT_10130	4.839e-26	113.0	COG0186@1|root,COG0186@2|Bacteria,2G722@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
REGS1_k127_3713443_26	926569.ANT_10120	4.794e-12	68.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
REGS1_k127_3713443_10	926569.ANT_10110	2.309e-62	217.0	COG0197@1|root,COG0197@2|Bacteria,2G6NA@200795|Chloroflexi	200795|Chloroflexi	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
REGS1_k127_3713443_3	926569.ANT_10100	2.658e-100	332.0	COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi	200795|Chloroflexi	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
REGS1_k127_3713443_21	926569.ANT_10090	7.225e-37	143.0	COG0091@1|root,COG0091@2|Bacteria,2G6ZQ@200795|Chloroflexi	200795|Chloroflexi	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
REGS1_k127_3713443_27	257314.LJ_0343	1.08e-08	56.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,3F6XP@33958|Lactobacillaceae	91061|Bacilli	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
REGS1_k127_3721192_1	926569.ANT_27130	2.936e-57	204.0	COG0592@1|root,COG0592@2|Bacteria,2G641@200795|Chloroflexi	200795|Chloroflexi	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
REGS1_k127_3721192_0	1174528.JH992887_gene6172	2.251e-66	231.0	COG0317@1|root,COG0317@2|Bacteria,1G68U@1117|Cyanobacteria	1117|Cyanobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
REGS1_k127_3721192_3	1380346.JNIH01000003_gene2020	5.166e-05	50.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4190
REGS1_k127_3721192_2	1347368.HG964404_gene5184	3.622e-17	87.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,4HNK6@91061|Bacilli,1ZHF1@1386|Bacillus	91061|Bacilli	L	Replication initiation and membrane attachment	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_2,Phg_2220_C
REGS1_k127_3725721_8	926569.ANT_02430	1.759e-23	107.0	2A1JS@1|root,30PTP@2|Bacteria,2G9H1@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3725721_4	926569.ANT_06220	1.437e-54	195.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
REGS1_k127_3725721_11	1144313.PMI10_02092	3.203e-13	74.0	COG4191@1|root,COG4191@2|Bacteria,4NSNP@976|Bacteroidetes,1I323@117743|Flavobacteriia,2NWR6@237|Flavobacterium	976|Bacteroidetes	T	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
REGS1_k127_3725721_3	926569.ANT_06230	1.488e-74	257.0	COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi	200795|Chloroflexi	J	PFAM Translin	-	-	-	ko:K07477	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_3725721_7	1121920.AUAU01000013_gene1720	2.581e-29	121.0	COG3613@1|root,COG3613@2|Bacteria	2|Bacteria	F	nucleoside 2-deoxyribosyltransferase	-	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	-	-	-	-	-	-	-	-	-	-	Nuc_deoxyrib_tr
REGS1_k127_3725721_1	391587.KAOT1_06197	1.073e-88	303.0	COG1216@1|root,COG1216@2|Bacteria,4PMN7@976|Bacteroidetes,1IJVF@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_3725721_5	391587.KAOT1_06182	1.195e-39	156.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
REGS1_k127_3725721_0	926569.ANT_25740	4.16e-136	460.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
REGS1_k127_3725721_10	926569.ANT_22190	4.064e-15	87.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
REGS1_k127_3725721_12	1150599.MPHLEI_21449	2.518e-11	75.0	COG2340@1|root,COG2340@2|Bacteria,2HS1Y@201174|Actinobacteria,23A5D@1762|Mycobacteriaceae	201174|Actinobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
REGS1_k127_3725721_6	1202962.KB907168_gene2246	1.366e-33	138.0	COG3714@1|root,COG3714@2|Bacteria,1PN0I@1224|Proteobacteria,1RNUV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane	yhhN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	YhhN
REGS1_k127_3725721_2	546414.Deide_03660	3.552e-85	291.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
REGS1_k127_3725721_9	1121352.JHZP01000006_gene1190	5.438e-20	91.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,2KPYD@206351|Neisseriales	206351|Neisseriales	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
REGS1_k127_3736010_3	1429046.RR21198_0288	1.506e-33	136.0	2CH4Q@1|root,338ZX@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4255)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4255
REGS1_k127_3736010_2	489825.LYNGBM3L_17620	6.296e-34	138.0	COG5126@1|root,COG5126@2|Bacteria,1G7DT@1117|Cyanobacteria,1HBQS@1150|Oscillatoriales	1117|Cyanobacteria	DTZ	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
REGS1_k127_3736010_4	1128421.JAGA01000002_gene45	2.118e-09	61.0	COG3847@1|root,COG3847@2|Bacteria	2|Bacteria	U	Flp Fap pilin component	pilA	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Class_IIIsignal,Flp_Fap
REGS1_k127_3736010_1	485913.Krac_0393	1.119e-36	149.0	COG1266@1|root,COG1266@2|Bacteria,2G772@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi
REGS1_k127_3736010_0	661478.OP10G_0321	2.177e-44	165.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	ykkB	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
REGS1_k127_3740903_0	926569.ANT_08450	4.308e-169	539.0	COG0399@1|root,COG0399@2|Bacteria,2G7Y0@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_3740903_1	1128421.JAGA01000002_gene331	6.097e-49	181.0	COG0442@1|root,COG0442@2|Bacteria,2NNNH@2323|unclassified Bacteria	2|Bacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
REGS1_k127_3749195_14	926569.ANT_22890	3.204e-10	60.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
REGS1_k127_3749195_1	216595.PFLU_1903	2.922e-199	628.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RQ8R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
REGS1_k127_3749195_5	926569.ANT_13990	1.405e-89	303.0	COG0524@1|root,COG0524@2|Bacteria,2G6PQ@200795|Chloroflexi	200795|Chloroflexi	G	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
REGS1_k127_3749195_2	926569.ANT_13980	3.035e-112	368.0	COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Cobyrinic acid a,c-diamide synthase	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
REGS1_k127_3749195_7	926569.ANT_13970	5.256e-80	275.0	COG1475@1|root,COG1475@2|Bacteria,2G6EK@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
REGS1_k127_3749195_15	926569.ANT_13960	9.909e-09	60.0	COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Amidohydrolase 3	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
REGS1_k127_3749195_10	1125863.JAFN01000001_gene577	1.861e-47	184.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
REGS1_k127_3749195_3	926569.ANT_13900	1.237e-111	377.0	COG0642@1|root,COG2205@2|Bacteria	926569.ANT_13900|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3749195_4	926569.ANT_13890	7.406e-104	342.0	COG0745@1|root,COG0745@2|Bacteria,2G8EP@200795|Chloroflexi	200795|Chloroflexi	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_3749195_11	926569.ANT_13860	8.956e-43	166.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
REGS1_k127_3749195_13	926569.ANT_13850	3.277e-24	108.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_13850|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3749195_8	926569.ANT_13840	7.191e-49	186.0	COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi	200795|Chloroflexi	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_3749195_6	1449126.JQKL01000016_gene2859	2.806e-89	302.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
REGS1_k127_3749195_12	1382356.JQMP01000003_gene1647	3.25e-37	150.0	COG1651@1|root,COG1651@2|Bacteria,2G8TG@200795|Chloroflexi,27YB4@189775|Thermomicrobia	189775|Thermomicrobia	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
REGS1_k127_3749195_0	234267.Acid_1182	4.448e-234	731.0	COG0076@1|root,COG0076@2|Bacteria,3Y2SW@57723|Acidobacteria	57723|Acidobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
REGS1_k127_3749195_9	926569.ANT_11280	1.39e-47	176.0	COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
REGS1_k127_3749195_16	7918.ENSLOCP00000000358	1.053e-06	54.0	KOG4475@1|root,KOG4475@2759|Eukaryota,39TF4@33154|Opisthokonta,3BK7M@33208|Metazoa,3D1ZY@33213|Bilateria,487GM@7711|Chordata,49KUS@7742|Vertebrata,49YEZ@7898|Actinopterygii	33208|Metazoa	P	Von Willebrand factor A domain-containing protein 7-like	-	-	-	-	-	-	-	-	-	-	-	-	Het-C,VWA_2
REGS1_k127_3751965_5	926550.CLDAP_37010	7.919e-75	259.0	COG0500@1|root,COG2226@2|Bacteria,2G6GD@200795|Chloroflexi	200795|Chloroflexi	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
REGS1_k127_3751965_8	304371.MCP_0717	4.154e-29	118.0	arCOG06908@1|root,arCOG06908@2157|Archaea,2Y41J@28890|Euryarchaeota,2NB0E@224756|Methanomicrobia	224756|Methanomicrobia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_3751965_4	1094980.Mpsy_0587	9.652e-110	363.0	COG1456@1|root,arCOG06909@2157|Archaea,2Y2FW@28890|Euryarchaeota,2NAAQ@224756|Methanomicrobia	224756|Methanomicrobia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhD
REGS1_k127_3751965_9	926550.CLDAP_36710	8.755e-27	113.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
REGS1_k127_3751965_2	926569.ANT_29900	2.69e-133	435.0	COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi	200795|Chloroflexi	S	Putative pyruvate format-lyase activating enzyme (DUF1786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1786
REGS1_k127_3751965_0	926569.ANT_16800	1.142e-227	715.0	COG1003@1|root,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
REGS1_k127_3751965_1	926569.ANT_16790	1.554e-182	581.0	COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
REGS1_k127_3751965_7	926569.ANT_16780	1.919e-29	121.0	COG0509@1|root,COG0509@2|Bacteria,2G6XE@200795|Chloroflexi	200795|Chloroflexi	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
REGS1_k127_3751965_10	926569.ANT_20810	2.631e-17	85.0	COG4818@1|root,COG4818@2|Bacteria,2G9PA@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4870)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870
REGS1_k127_3751965_3	926569.ANT_20820	6.774e-111	366.0	COG0223@1|root,COG0223@2|Bacteria,2G69J@200795|Chloroflexi	200795|Chloroflexi	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
REGS1_k127_3751965_6	926569.ANT_27610	1.022e-70	242.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	200795|Chloroflexi	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
REGS1_k127_3759809_1	926550.CLDAP_31520	1.511e-43	161.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi	200795|Chloroflexi	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
REGS1_k127_3759809_0	224325.AF_2036	8.205e-44	171.0	COG0109@1|root,arCOG00479@2157|Archaea,2XUEM@28890|Euryarchaeota,247C6@183980|Archaeoglobi	183980|Archaeoglobi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
REGS1_k127_3765389_0	1068980.ARVW01000001_gene4454	2.506e-135	440.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,4DX61@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Cys Met metabolism	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
REGS1_k127_3765389_1	335543.Sfum_4027	8.824e-105	354.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,2MQDN@213462|Syntrophobacterales	1224|Proteobacteria	KT	Stage II sporulation	icfG	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c_2,SpoIIE,dCache_1,dCache_2,sCache_2
REGS1_k127_3765389_2	926569.ANT_13390	1.257e-97	326.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
REGS1_k127_3765389_3	32264.tetur05g07830.1	4.307e-14	80.0	KOG4351@1|root,KOG4351@2759|Eukaryota,38HHX@33154|Opisthokonta,3B9X5@33208|Metazoa,3CU75@33213|Bilateria,41Z0F@6656|Arthropoda	33208|Metazoa	S	Ig-like domain from next to BRCA1 gene	C6orf106	GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919	-	-	-	-	-	-	-	-	-	-	N_BRCA1_IG,UBA_4
REGS1_k127_3803870_2	1410665.JNKR01000001_gene492	4.416e-65	225.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H2E8@909932|Negativicutes	909932|Negativicutes	E	ABC transporter, ATP-binding protein	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
REGS1_k127_3803870_1	926569.ANT_11730	1.344e-112	374.0	COG0416@1|root,COG0416@2|Bacteria,2G5Z8@200795|Chloroflexi	200795|Chloroflexi	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
REGS1_k127_3803870_4	926569.ANT_11720	3.132e-41	162.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NERD
REGS1_k127_3803870_0	926569.ANT_15410	0.0	1086.0	COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,2G5P4@200795|Chloroflexi	200795|Chloroflexi	L	PFAM Exonuclease, RNase T and DNA polymerase III	-	-	2.7.7.7,3.6.4.12	ko:K02342,ko:K03722	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RNase_T
REGS1_k127_3803870_8	439235.Dalk_3192	2.244e-13	76.0	COG1028@1|root,COG2030@1|root,COG3255@1|root,COG1028@2|Bacteria,COG2030@2|Bacteria,COG3255@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria,2MHRA@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas,SCP2,adh_short
REGS1_k127_3803870_6	926569.ANT_20480	3.31e-25	111.0	2ESS5@1|root,33KAI@2|Bacteria,2G7C4@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3803870_7	926569.ANT_20470	2.986e-20	95.0	COG4980@1|root,COG4980@2|Bacteria	2|Bacteria	D	gas vesicle protein	XK27_07760	-	-	-	-	-	-	-	-	-	-	-	YtxH
REGS1_k127_3803870_5	1128421.JAGA01000002_gene1700	8.094e-36	149.0	COG0500@1|root,COG2226@2|Bacteria,2NRJA@2323|unclassified Bacteria	2|Bacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
REGS1_k127_3803870_3	37659.JNLN01000001_gene188	2.79e-57	208.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,36HYG@31979|Clostridiaceae	186801|Clostridia	S	channel protein, hemolysin III family	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
REGS1_k127_381094_1	1121403.AUCV01000004_gene1965	2.131e-98	329.0	COG1299@1|root,COG1445@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,1MXFN@1224|Proteobacteria,42YSY@68525|delta/epsilon subdivisions,2WTNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PTS system, Lactose/Cellobiose specific IIB subunit	-	-	2.7.1.202	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIC,PTS_IIB
REGS1_k127_381094_2	765913.ThidrDRAFT_0839	9.48e-97	325.0	COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,1RP6K@1236|Gammaproteobacteria,1X2EI@135613|Chromatiales	135613|Chromatiales	H	belongs to the carbohydrate kinase PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
REGS1_k127_381094_0	765913.ThidrDRAFT_0838	1.462e-110	361.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,1WXBA@135613|Chromatiales	135613|Chromatiales	G	PEP-utilising enzyme, mobile	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr,PTS_EIIA_2
REGS1_k127_381094_3	666681.M301_1127	2.856e-25	105.0	COG1080@1|root,COG1925@1|root,COG4668@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG4668@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,2KKUE@206350|Nitrosomonadales	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
REGS1_k127_3812248_18	926569.ANT_13190	6.003e-56	201.0	COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_3812248_32	765420.OSCT_2858	7.661e-20	102.0	COG0515@1|root,COG0515@2|Bacteria,2GACY@200795|Chloroflexi,375GK@32061|Chloroflexia	32061|Chloroflexia	KLT	SMART tyrosine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
REGS1_k127_3812248_40	700508.D174_25155	1.24e-07	59.0	2E8H6@1|root,332VD@2|Bacteria,2II1R@201174|Actinobacteria,238XJ@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
REGS1_k127_3812248_12	485916.Dtox_1611	2.27e-112	369.0	COG0535@1|root,COG0535@2|Bacteria,1URM8@1239|Firmicutes,24XB8@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
REGS1_k127_3812248_34	1276920.ADIAG_03626	1.201e-10	72.0	COG1266@1|root,COG1266@2|Bacteria,2IID1@201174|Actinobacteria,1W9ZD@1268|Micrococcaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
REGS1_k127_3812248_13	926569.ANT_19840	2.573e-101	334.0	COG0035@1|root,COG0035@2|Bacteria,2G6CS@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
REGS1_k127_3812248_19	1499686.BN1079_02482	2.446e-55	199.0	COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria,1SGBM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_3812248_5	56780.SYN_01159	9.071e-134	435.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WMDC@28221|Deltaproteobacteria,2MREJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_3812248_39	1210884.HG799463_gene9840	7.497e-08	58.0	COG3070@1|root,COG3070@2|Bacteria,2J0Y3@203682|Planctomycetes	203682|Planctomycetes	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
REGS1_k127_3812248_38	1089552.KI911559_gene670	6.609e-08	57.0	COG4106@1|root,COG4106@2|Bacteria,1R04W@1224|Proteobacteria,2U5VR@28211|Alphaproteobacteria,2JRTB@204441|Rhodospirillales	204441|Rhodospirillales	S	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_3812248_22	316058.RPB_3231	2.356e-50	202.0	2DM0M@1|root,3175D@2|Bacteria,1MYGG@1224|Proteobacteria,2UA4C@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3812248_20	926569.ANT_19290	9.237e-55	200.0	2EV3Q@1|root,33NIR@2|Bacteria,2G9SC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3812248_15	926569.ANT_19280	1.893e-85	290.0	COG0149@1|root,COG0149@2|Bacteria,2G69W@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
REGS1_k127_3812248_42	1131814.JAFO01000001_gene1639	0.0003293	49.0	2EAED@1|root,334HY@2|Bacteria,1NBI0@1224|Proteobacteria,2UG13@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3812248_3	926550.CLDAP_03690	1.535e-155	501.0	COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
REGS1_k127_3812248_7	273068.TTE1762	9.499e-127	415.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,42F8D@68295|Thermoanaerobacterales	186801|Clostridia	C	TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
REGS1_k127_3812248_0	926569.ANT_13260	9.515e-164	527.0	COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi	200795|Chloroflexi	S	Required for morphogenesis under gluconeogenic growth conditions	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
REGS1_k127_3812248_6	926569.ANT_08950	2.159e-128	439.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,2GA77@200795|Chloroflexi	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
REGS1_k127_3812248_26	861299.J421_1282	1.312e-44	178.0	COG2911@1|root,COG3209@1|root,COG4625@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_5,CHU_C,Calx-beta,DUF4347,HemolysinCabind,PATR
REGS1_k127_3812248_24	479434.Sthe_2302	1.102e-46	188.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
REGS1_k127_3812248_8	926569.ANT_08920	5.685e-122	398.0	COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_3812248_14	926569.ANT_08910	1.615e-89	312.0	COG0037@1|root,COG0037@2|Bacteria,2G6AD@200795|Chloroflexi	200795|Chloroflexi	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	2.4.2.8,6.3.4.19	ko:K00760,ko:K04075,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245,R09597	RC00063,RC00122,RC02633,RC02634	ko00000,ko00001,ko01000,ko03016	-	-	-	ATP_bind_3,Pribosyltran,TilS,TilS_C
REGS1_k127_3812248_25	926569.ANT_02700	3.913e-45	168.0	COG0346@1|root,COG0346@2|Bacteria,2G79M@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
REGS1_k127_3812248_21	7897.ENSLACP00000010670	3.153e-51	186.0	COG1437@1|root,KOG2589@2759|Eukaryota,3A4QC@33154|Opisthokonta,3BRFI@33208|Metazoa,3D8WI@33213|Bilateria,48EHS@7711|Chordata,49BAX@7742|Vertebrata	33208|Metazoa	F	CYTH domain	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
REGS1_k127_3812248_17	478741.JAFS01000001_gene1555	1.92e-67	239.0	28I4Y@1|root,2Z88D@2|Bacteria,46VRF@74201|Verrucomicrobia,37GMA@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3812248_28	926560.KE387023_gene2407	3.371e-39	152.0	COG1832@1|root,COG1832@2|Bacteria	2|Bacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
REGS1_k127_3812248_29	357808.RoseRS_4198	1.188e-30	129.0	2E64T@1|root,330TJ@2|Bacteria,2G93I@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3812248_36	485917.Phep_3458	1.117e-09	68.0	2AX7X@1|root,31P6Q@2|Bacteria,4NGGX@976|Bacteroidetes,1IURY@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3812248_33	768671.ThimaDRAFT_1522	9.911e-17	87.0	2DRNI@1|root,33CD9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3812248_4	357808.RoseRS_0975	7.734e-142	460.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,376G0@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
REGS1_k127_3812248_10	326427.Cagg_0709	3.509e-115	383.0	COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,377SH@32061|Chloroflexia	32061|Chloroflexia	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
REGS1_k127_3812248_16	926569.ANT_17320	3.701e-85	291.0	29XJU@1|root,30JAW@2|Bacteria,2G9DS@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3812248_27	326427.Cagg_1297	7.498e-40	160.0	COG0204@1|root,COG0204@2|Bacteria,2G92W@200795|Chloroflexi,3779N@32061|Chloroflexia	32061|Chloroflexia	I	PFAM phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
REGS1_k127_3812248_23	251221.35213751	3.279e-50	192.0	COG0363@1|root,COG0363@2|Bacteria,1G20H@1117|Cyanobacteria	1117|Cyanobacteria	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
REGS1_k127_3812248_9	1267533.KB906734_gene3722	2.165e-117	387.0	COG1023@1|root,COG1023@2|Bacteria,3Y2ZP@57723|Acidobacteria,2JHSA@204432|Acidobacteriia	204432|Acidobacteriia	G	6-phosphogluconate dehydrogenase (Decarboxylating)	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
REGS1_k127_3812248_2	595460.RRSWK_00040	3.468e-161	521.0	COG0364@1|root,COG0364@2|Bacteria,2IXCV@203682|Planctomycetes	203682|Planctomycetes	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
REGS1_k127_3812248_30	484770.UFO1_1184	4.296e-29	129.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,1UZZ7@1239|Firmicutes,4H3PK@909932|Negativicutes	909932|Negativicutes	V	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
REGS1_k127_3812248_31	926569.ANT_01110	6.131e-26	120.0	COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
REGS1_k127_3812248_11	357808.RoseRS_3212	5.253e-113	376.0	COG0664@1|root,COG1136@1|root,COG0664@2|Bacteria,COG1136@2|Bacteria,2G6C9@200795|Chloroflexi,37685@32061|Chloroflexia	32061|Chloroflexia	V	ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,cNMP_binding
REGS1_k127_3812248_1	697282.Mettu_4284	9.263e-163	541.0	COG0577@1|root,COG0577@2|Bacteria,1PJZX@1224|Proteobacteria,1RU56@1236|Gammaproteobacteria,1XDTW@135618|Methylococcales	135618|Methylococcales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_3812248_37	1071679.BG57_15620	2.353e-09	65.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VJ2I@28216|Betaproteobacteria,1K4EU@119060|Burkholderiaceae	28216|Betaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
REGS1_k127_3812248_35	1134474.O59_003510	9.18e-10	71.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1S5PP@1236|Gammaproteobacteria,1FGCV@10|Cellvibrio	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, crp family	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Crp,HTH_Crp_2,cNMP_binding
REGS1_k127_3812248_41	391623.TERMP_00740	5.111e-05	55.0	COG0477@1|root,arCOG00135@2157|Archaea,2XYRS@28890|Euryarchaeota,242QK@183968|Thermococci	183968|Thermococci	G	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2
REGS1_k127_3846106_0	926569.ANT_15860	0.0	1198.0	COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi	200795|Chloroflexi	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298,PMT_2,TPR_16,TPR_19,TPR_8
REGS1_k127_3846106_2	1042163.BRLA_c040090	1.901e-26	113.0	COG3502@1|root,COG3502@2|Bacteria,1V8W5@1239|Firmicutes,4HQG5@91061|Bacilli,2708U@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
REGS1_k127_3846106_1	926550.CLDAP_30390	2.823e-86	302.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
REGS1_k127_3867618_12	926569.ANT_11750	8.406e-56	205.0	COG0745@1|root,COG0745@2|Bacteria,2G8W7@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_3867618_5	926569.ANT_11740	2.654e-137	454.0	COG2203@1|root,COG2204@1|root,COG4191@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG4191@2|Bacteria,2G6UY@200795|Chloroflexi	200795|Chloroflexi	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
REGS1_k127_3867618_13	357808.RoseRS_0231	1.296e-51	209.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,2G7Y4@200795|Chloroflexi,374VX@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,Response_reg
REGS1_k127_3867618_2	926569.ANT_16920	1.141e-180	577.0	COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	-	-	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
REGS1_k127_3867618_9	926569.ANT_16930	3.247e-84	288.0	COG2234@1|root,COG2234@2|Bacteria,2G6WJ@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
REGS1_k127_3867618_1	926569.ANT_16960	2.212e-186	593.0	COG2262@1|root,COG2262@2|Bacteria,2G634@200795|Chloroflexi	200795|Chloroflexi	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
REGS1_k127_3867618_16	326427.Cagg_2825	8.363e-15	88.0	COG1807@1|root,COG1807@2|Bacteria,2GAAY@200795|Chloroflexi,374TV@32061|Chloroflexia	32061|Chloroflexia	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_3867618_0	945713.IALB_1079	1.238e-227	717.0	COG1866@1|root,COG1866@2|Bacteria	2|Bacteria	H	phosphoenolpyruvate carboxykinase (ATP) activity	pckA	GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
REGS1_k127_3867618_4	1191523.MROS_1373	1.617e-142	464.0	COG0436@1|root,COG0436@2|Bacteria	2|Bacteria	E	Aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_3867618_11	997346.HMPREF9374_0897	3.099e-69	246.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli,27BCT@186824|Thermoactinomycetaceae	91061|Bacilli	I	Acyl transferase domain	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
REGS1_k127_3867618_15	926569.ANT_16980	3.431e-24	104.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
REGS1_k127_3867618_10	926569.ANT_16730	7.922e-81	276.0	COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi	200795|Chloroflexi	KT	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
REGS1_k127_3867618_14	926569.ANT_16750	7.891e-25	109.0	COG0125@1|root,COG0125@2|Bacteria,2GBP3@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3867618_7	926569.ANT_16760	2.535e-133	441.0	COG0342@1|root,COG0342@2|Bacteria,2G5K5@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
REGS1_k127_3867618_8	926569.ANT_16770	1.706e-87	299.0	COG0341@1|root,COG0341@2|Bacteria,2G696@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
REGS1_k127_3867618_6	1192034.CAP_6029	2.64e-135	437.0	COG1611@1|root,COG1611@2|Bacteria,1R7TB@1224|Proteobacteria,43F31@68525|delta/epsilon subdivisions,2X36V@28221|Deltaproteobacteria,2YUKD@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3867618_3	1499967.BAYZ01000159_gene536	1.116e-145	467.0	COG3384@1|root,COG3384@2|Bacteria	2|Bacteria	S	3-carboxyethylcatechol 2,3-dioxygenase activity	-	-	1.13.11.8	ko:K04100	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigA,LigB
REGS1_k127_3868608_4	926569.ANT_13780	5.214e-22	96.0	COG0224@1|root,COG0224@2|Bacteria,2G69I@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
REGS1_k127_3868608_0	926569.ANT_13790	1.304e-242	755.0	COG0055@1|root,COG0055@2|Bacteria,2G5JI@200795|Chloroflexi	200795|Chloroflexi	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
REGS1_k127_3868608_3	926569.ANT_13800	1.413e-49	180.0	COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi	200795|Chloroflexi	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
REGS1_k127_3868608_1	926550.CLDAP_05030	2.54e-104	351.0	COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
REGS1_k127_3868608_2	926569.ANT_13820	2.069e-75	258.0	COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi	200795|Chloroflexi	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
REGS1_k127_3894587_6	926569.ANT_17290	1.175e-34	137.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
REGS1_k127_3894587_4	926569.ANT_17280	2.877e-97	325.0	COG1028@1|root,COG1028@2|Bacteria,2G8P1@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_3894587_7	926569.ANT_17270	8.46e-28	117.0	COG1547@1|root,COG1547@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF309)	ypuF	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
REGS1_k127_3894587_8	926569.ANT_09570	3.44e-16	89.0	2ECS5@1|root,336PT@2|Bacteria,2G96H@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
REGS1_k127_3894587_10	1499967.BAYZ01000089_gene5036	2.769e-06	57.0	293D3@1|root,2ZQVN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3894587_1	383372.Rcas_2912	4.739e-135	436.0	COG0714@1|root,COG0714@2|Bacteria,2G8BI@200795|Chloroflexi,377XH@32061|Chloroflexia	32061|Chloroflexia	S	PFAM ATPase associated with various cellular activities, AAA_3	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_3894587_3	357808.RoseRS_3183	6.628e-105	355.0	COG1721@1|root,COG1721@2|Bacteria,2G7JJ@200795|Chloroflexi	200795|Chloroflexi	M	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_3894587_0	2045.KR76_16090	1.748e-142	466.0	COG0160@1|root,COG0160@2|Bacteria,2I2F3@201174|Actinobacteria,4DP1H@85009|Propionibacteriales	201174|Actinobacteria	E	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
REGS1_k127_3894587_2	324602.Caur_2066	5.647e-106	352.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi,376IE@32061|Chloroflexia	32061|Chloroflexia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_3894587_5	357808.RoseRS_0253	1.746e-58	207.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,374VR@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
REGS1_k127_3904986_1	926569.ANT_22530	5.819e-43	165.0	COG5011@1|root,COG5011@2|Bacteria,2G71I@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
REGS1_k127_3904986_0	765420.OSCT_3068	1.103e-81	283.0	COG2339@1|root,COG2339@2|Bacteria,2G946@200795|Chloroflexi,375Y0@32061|Chloroflexia	32061|Chloroflexia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
REGS1_k127_3904986_4	1004785.AMBLS11_13975	2.163e-14	89.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,1S3NR@1236|Gammaproteobacteria,466TA@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iECP_1309.ECP_0104	CoaE
REGS1_k127_3904986_2	926692.AZYG01000038_gene1071	1.712e-28	135.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WBJC@53433|Halanaerobiales	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_3915187_0	926569.ANT_01520	2.208e-182	576.0	COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi	200795|Chloroflexi	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
REGS1_k127_3915187_2	926569.ANT_23030	1.152e-94	330.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_3,Peptidase_M23
REGS1_k127_3915187_1	926569.ANT_23020	3.966e-150	496.0	COG0823@1|root,COG0823@2|Bacteria,2G8PZ@200795|Chloroflexi	200795|Chloroflexi	U	WD40 domain protein beta Propeller	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
REGS1_k127_3915187_3	926569.ANT_30620	3.397e-90	300.0	COG1932@1|root,COG1932@2|Bacteria,2G7RM@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
REGS1_k127_3929599_3	1499967.BAYZ01000067_gene6045	2.142e-71	250.0	COG0395@1|root,COG0395@2|Bacteria,2NPBC@2323|unclassified Bacteria	2|Bacteria	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
REGS1_k127_3929599_4	1499967.BAYZ01000067_gene6044	9.432e-62	223.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
REGS1_k127_3929599_5	1122919.KB905571_gene3065	2.006e-48	191.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,4HA0U@91061|Bacilli,26VZR@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
REGS1_k127_3929599_1	1303518.CCALI_00632	5.833e-114	381.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_3929599_0	383372.Rcas_2791	8.68e-141	456.0	COG0673@1|root,COG0673@2|Bacteria,2G7YW@200795|Chloroflexi	200795|Chloroflexi	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_3929599_6	1089548.KI783301_gene231	2.967e-43	167.0	COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,4HFJQ@91061|Bacilli,3WFT5@539002|Bacillales incertae sedis	91061|Bacilli	S	GlcNAc-PI de-N-acetylase	bshB1	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
REGS1_k127_3929599_2	1499967.BAYZ01000109_gene2967	3.436e-104	346.0	COG1028@1|root,COG1028@2|Bacteria,2NPDM@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_3960941_3	926569.ANT_20420	1.063e-106	361.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
REGS1_k127_3960941_4	926569.ANT_20430	1.094e-73	252.0	COG0193@1|root,COG0193@2|Bacteria,2G6SW@200795|Chloroflexi	200795|Chloroflexi	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
REGS1_k127_3960941_7	926569.ANT_20440	3.033e-16	87.0	COG1376@1|root,COG1376@2|Bacteria,2G9TK@200795|Chloroflexi	200795|Chloroflexi	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3960941_6	926569.ANT_03760	4.732e-47	172.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
REGS1_k127_3960941_0	926569.ANT_25410	1.657e-267	834.0	COG0504@1|root,COG0504@2|Bacteria,2G5U0@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
REGS1_k127_3960941_1	926569.ANT_20720	5.524e-174	552.0	COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
REGS1_k127_3960941_2	649638.Trad_2961	9.099e-164	530.0	COG0366@1|root,COG0366@2|Bacteria,1WIU5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	PFAM alpha amylase, catalytic	-	-	3.2.1.133,3.2.1.135,3.2.1.54	ko:K01208	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
REGS1_k127_3960941_5	395493.BegalDRAFT_3427	2.794e-72	248.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,1RMX5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	cobB	GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
REGS1_k127_3994196_6	78345.BMERY_3013	0.0002412	49.0	COG3311@1|root,COG3311@2|Bacteria	2|Bacteria	K	DNA excision	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17,Response_reg
REGS1_k127_3994196_1	573413.Spirs_3930	1.545e-57	205.0	COG0454@1|root,COG0456@2|Bacteria,2J948@203691|Spirochaetes	203691|Spirochaetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_10
REGS1_k127_3994196_0	994573.T472_0218755	5.947e-109	363.0	28PJ3@1|root,2ZC8W@2|Bacteria,1V220@1239|Firmicutes,24IPD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3994196_3	869210.Marky_1921	3.779e-26	114.0	COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
REGS1_k127_3994196_5	446465.Bfae_31740	0.0001622	48.0	2DEA8@1|root,2ZM5C@2|Bacteria,2HM1J@201174|Actinobacteria,4FD8Z@85020|Dermabacteraceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3994196_2	304371.MCP_2791	2.023e-40	164.0	COG0477@1|root,arCOG00130@2157|Archaea,2XX8J@28890|Euryarchaeota,2NB8J@224756|Methanomicrobia	224756|Methanomicrobia	G	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like
REGS1_k127_3995138_0	926569.ANT_14080	1.044e-275	883.0	COG0542@1|root,COG0542@2|Bacteria,2G5QU@200795|Chloroflexi	200795|Chloroflexi	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_3995138_1	180332.JTGN01000001_gene4745	1.347e-95	329.0	COG1653@1|root,COG1653@2|Bacteria,1W04F@1239|Firmicutes,2543W@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
REGS1_k127_3995138_2	1284352.AOIG01000010_gene1994	9.53e-09	60.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HBZ4@91061|Bacilli,274SP@186822|Paenibacillaceae	91061|Bacilli	P	ABC-type sugar transport systems, permease components	ugpA3	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
REGS1_k127_4039996_1	926569.ANT_28330	2.525e-151	497.0	COG0608@1|root,COG0608@2|Bacteria,2G7JK@200795|Chloroflexi	200795|Chloroflexi	L	DHH family	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
REGS1_k127_4039996_0	1174528.JH992892_gene6439	1.05e-203	643.0	COG3033@1|root,COG3033@2|Bacteria,1G33V@1117|Cyanobacteria	1117|Cyanobacteria	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Beta_elim_lyase
REGS1_k127_4039996_2	1242864.D187_001151	7.321e-58	212.0	COG1181@1|root,COG1181@2|Bacteria,1Q3H4@1224|Proteobacteria,4399M@68525|delta/epsilon subdivisions,2X4H1@28221|Deltaproteobacteria,2YZ01@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
REGS1_k127_4130825_2	926569.ANT_13310	1.121e-102	350.0	2DMUC@1|root,32TQR@2|Bacteria,2G6MF@200795|Chloroflexi	200795|Chloroflexi	S	CpXC protein	-	-	-	-	-	-	-	-	-	-	-	-	CpXC
REGS1_k127_4130825_4	479434.Sthe_2989	1.105e-74	266.0	COG0477@1|root,COG2814@2|Bacteria,2G6D7@200795|Chloroflexi	2|Bacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
REGS1_k127_4130825_5	926569.ANT_16090	2.562e-58	209.0	COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi	200795|Chloroflexi	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_4130825_3	926569.ANT_16080	8.282e-84	291.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,MFS_3,Sugar_tr
REGS1_k127_4130825_6	402777.KB235904_gene3327	3.039e-38	160.0	2ECWT@1|root,30T28@2|Bacteria,1GDVQ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4130825_1	926569.ANT_16070	5.333e-118	389.0	COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M24	-	-	3.4.13.9	ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Creatinase_N,Peptidase_M24
REGS1_k127_4130825_0	926569.ANT_15300	1.175e-203	641.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_4140568_4	477974.Daud_1296	4.867e-71	249.0	2ASZS@1|root,31IFG@2|Bacteria,1V50D@1239|Firmicutes,24PRN@186801|Clostridia,262PV@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4140568_2	290512.Paes_1663	5.414e-155	501.0	COG1271@1|root,COG1271@2|Bacteria,1FDQV@1090|Chlorobi	1090|Chlorobi	C	PFAM cytochrome bd ubiquinol oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
REGS1_k127_4140568_3	880073.Calab_0286	7.665e-128	417.0	COG1294@1|root,COG1294@2|Bacteria,2NS31@2323|unclassified Bacteria	2|Bacteria	C	PFAM Cytochrome bd ubiquinol oxidase, subunit II	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,iYO844.BSU38750,ic_1306.c1120	Cyt_bd_oxida_II
REGS1_k127_4140568_0	765420.OSCT_1692	7.913e-249	813.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2G7JB@200795|Chloroflexi	200795|Chloroflexi	CO	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	-	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
REGS1_k127_4140568_1	926569.ANT_09360	2.582e-219	686.0	COG1158@1|root,COG1158@2|Bacteria,2G5UQ@200795|Chloroflexi	200795|Chloroflexi	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
REGS1_k127_4140568_5	926569.ANT_09370	5.838e-57	213.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
REGS1_k127_4140568_6	1122609.AUGT01000013_gene4183	2.217e-10	64.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,4DQT5@85009|Propionibacteriales	201174|Actinobacteria	H	Biotin/lipoate A/B protein ligase family	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
REGS1_k127_41639_6	1150600.ADIARSV_3703	5.511e-15	79.0	COG1005@1|root,COG1005@2|Bacteria,4NGK7@976|Bacteroidetes,1IR49@117747|Sphingobacteriia	976|Bacteroidetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
REGS1_k127_41639_3	926569.ANT_08370	5.441e-81	272.0	COG1143@1|root,COG1143@2|Bacteria,2G6P8@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
REGS1_k127_41639_4	926569.ANT_08380	6.013e-38	149.0	COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the complex I subunit 6 family	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
REGS1_k127_41639_5	1521187.JPIM01000094_gene1025	4.556e-33	130.0	COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi,375TW@32061|Chloroflexia	32061|Chloroflexia	F	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
REGS1_k127_41639_0	926569.ANT_08400	2.384e-222	710.0	COG1009@1|root,COG1009@2|Bacteria,2G5NJ@200795|Chloroflexi	200795|Chloroflexi	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
REGS1_k127_41639_1	926569.ANT_08410	3.375e-216	681.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
REGS1_k127_41639_2	926569.ANT_08420	5.843e-155	502.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
REGS1_k127_4193767_7	1340434.AXVA01000033_gene10	9.069e-08	57.0	COG1814@1|root,COG1814@2|Bacteria,1V011@1239|Firmicutes,4I36W@91061|Bacilli,1ZE9R@1386|Bacillus	91061|Bacilli	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
REGS1_k127_4193767_8	1033802.SSPSH_002681	4.328e-05	51.0	2CIUH@1|root,32S8I@2|Bacteria,1N51U@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4193767_4	1120746.CCNL01000017_gene2423	8.189e-69	247.0	COG1597@1|root,COG1597@2|Bacteria	2|Bacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
REGS1_k127_4193767_5	1120746.CCNL01000017_gene2422	4.922e-51	191.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	pgpB1	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
REGS1_k127_4193767_3	1459636.NTE_03442	2.957e-73	250.0	COG5483@1|root,arCOG00723@2157|Archaea	2157|Archaea	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
REGS1_k127_4193767_6	1713.JOFV01000004_gene3311	1.091e-13	79.0	2EG8Z@1|root,332XF@2|Bacteria,2GTHG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4193767_9	1382356.JQMP01000004_gene226	0.0003759	47.0	COG3427@1|root,COG3427@2|Bacteria,2G6U6@200795|Chloroflexi,27YFP@189775|Thermomicrobia	189775|Thermomicrobia	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
REGS1_k127_4193767_2	765420.OSCT_2447	2.224e-84	292.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi,37650@32061|Chloroflexia	32061|Chloroflexia	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
REGS1_k127_4193767_1	1382356.JQMP01000004_gene357	4.012e-122	398.0	COG1079@1|root,COG1079@2|Bacteria,2GAAR@200795|Chloroflexi,27Z2F@189775|Thermomicrobia	189775|Thermomicrobia	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
REGS1_k127_4193767_0	1382356.JQMP01000004_gene358	8.899e-124	406.0	COG4603@1|root,COG4603@2|Bacteria,2GA3M@200795|Chloroflexi,27Z1Y@189775|Thermomicrobia	189775|Thermomicrobia	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
REGS1_k127_4198232_1	1123242.JH636438_gene5776	3.788e-10	63.0	COG0110@1|root,COG0663@1|root,COG1020@1|root,COG0110@2|Bacteria,COG0663@2|Bacteria,COG1020@2|Bacteria,2IZDX@203682|Planctomycetes	203682|Planctomycetes	Q	Amino acid adenylation domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
REGS1_k127_4198232_0	324925.Ppha_2593	9.972e-191	611.0	COG5421@1|root,COG5421@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
REGS1_k127_4203887_0	330214.NIDE3303	1.831e-286	891.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
REGS1_k127_4265651_4	926569.ANT_05540	4.473e-23	106.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
REGS1_k127_4265651_3	926550.CLDAP_25160	2.811e-42	163.0	COG2030@1|root,COG2030@2|Bacteria,2G6Y9@200795|Chloroflexi	200795|Chloroflexi	I	MaoC domain protein dehydratase	-	-	2.3.1.19,4.2.1.55	ko:K00634,ko:K17865	ko00630,ko00650,ko01100,ko01120,ko01200,map00630,map00650,map01100,map01120,map01200	M00373	R01174,R03027	RC00004,RC00831,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	MaoC_dehydratas,PTA_PTB
REGS1_k127_4265651_0	243231.GSU1966	5.172e-185	587.0	COG4310@1|root,COG4310@2|Bacteria,1NDWT@1224|Proteobacteria,42PN9@68525|delta/epsilon subdivisions,2WPQV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47,Peptidase_M28
REGS1_k127_4265651_1	511.JT27_09380	9.639e-94	317.0	COG2746@1|root,COG2746@2|Bacteria,1PXFA@1224|Proteobacteria,2WCVN@28216|Betaproteobacteria,3T8E8@506|Alcaligenaceae	28216|Betaproteobacteria	V	Aminoglycoside 3-N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Antibiotic_NAT
REGS1_k127_4265651_2	767817.Desgi_4716	4.786e-54	212.0	COG1807@1|root,COG1807@2|Bacteria,1VXPG@1239|Firmicutes,251Y3@186801|Clostridia	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_427516_3	234267.Acid_0752	3.989e-06	49.0	COG0517@1|root,COG0517@2|Bacteria,3Y8IB@57723|Acidobacteria	57723|Acidobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
REGS1_k127_427516_1	1123393.KB891326_gene87	8.18e-288	891.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_427516_2	269799.Gmet_2621	9.36e-14	75.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42ZZI@68525|delta/epsilon subdivisions,2WV7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Ribose galactose isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2621	LacAB_rpiB
REGS1_k127_427516_0	706587.Desti_2109	5.243e-295	925.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions,2WIXQ@28221|Deltaproteobacteria,2MRG0@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
REGS1_k127_4275315_2	383372.Rcas_3422	3.55e-05	51.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	ko:K09766	-	-	-	-	ko00000	-	-	-	YSIRK_signal
REGS1_k127_4275315_1	1045855.DSC_10500	1.153e-17	88.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,1RMW9@1236|Gammaproteobacteria,1X3E9@135614|Xanthomonadales	135614|Xanthomonadales	G	COG3459 Cellobiose phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_4275315_0	765420.OSCT_2127	1.532e-107	365.0	2CVPW@1|root,32SXZ@2|Bacteria,2G7DV@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4299048_0	1288963.ADIS_1517	6.109e-21	94.0	COG1061@1|root,COG1061@2|Bacteria,4NJ7R@976|Bacteroidetes,47NCC@768503|Cytophagia	976|Bacteroidetes	L	Type III restriction enzyme, res subunit	-	-	3.1.21.5	ko:K01156	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	ResIII
REGS1_k127_4299048_1	1304865.JAGF01000001_gene965	3.769e-16	83.0	2EG8Z@1|root,33A0S@2|Bacteria,2I8BH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4299048_3	926569.ANT_23800	0.000488	48.0	COG4974@1|root,COG4974@2|Bacteria	926569.ANT_23800|-	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	-
REGS1_k127_4299048_2	1166018.FAES_1437	4.655e-07	57.0	2EEN1@1|root,338FZ@2|Bacteria,4NX91@976|Bacteroidetes,47SDH@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4326538_0	926569.ANT_30000	3.984e-178	575.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
REGS1_k127_4326538_1	926569.ANT_05600	8.59e-07	55.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_43638_1	2340.JV46_02070	7.284e-05	57.0	COG3202@1|root,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	-	-	-	ko:K03301	-	-	-	-	ko00000	2.A.12	-	-	HEAT_2,TLC,cNMP_binding
REGS1_k127_43638_0	2340.JV46_02050	6.52e-59	234.0	COG0664@1|root,COG3202@1|root,COG0664@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria	1224|Proteobacteria	CT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
REGS1_k127_4367592_2	1128421.JAGA01000003_gene3664	3.593e-66	231.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	steT	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
REGS1_k127_4367592_1	1128421.JAGA01000003_gene3665	6.753e-108	357.0	COG2129@1|root,COG2129@2|Bacteria	2|Bacteria	L	metallophosphoesterase	-	-	-	ko:K07096,ko:K07496	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2,Metallophos_3
REGS1_k127_4367592_0	1487923.DP73_19985	4.528e-170	544.0	COG5598@1|root,COG5598@2|Bacteria,1V08E@1239|Firmicutes,24BDE@186801|Clostridia,263XC@186807|Peptococcaceae	186801|Clostridia	H	Trimethylamine methyltransferase	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
REGS1_k127_4387019_5	886293.Sinac_4680	3.559e-11	75.0	COG4932@1|root,COG4932@2|Bacteria,2IYDU@203682|Planctomycetes	203682|Planctomycetes	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
REGS1_k127_4387019_2	272557.APE_0122.1	1.017e-52	191.0	COG0537@1|root,arCOG00419@2157|Archaea,2XQK8@28889|Crenarchaeota	28889|Crenarchaeota	F	PFAM histidine triad (HIT) protein	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
REGS1_k127_4387019_0	926569.ANT_26230	3.446e-125	412.0	COG1570@1|root,COG1570@2|Bacteria,2G5M3@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
REGS1_k127_4387019_4	926569.ANT_26240	1.444e-11	67.0	COG1722@1|root,COG1722@2|Bacteria,2G7IN@200795|Chloroflexi	200795|Chloroflexi	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
REGS1_k127_4387019_3	926569.ANT_26250	6.773e-47	173.0	COG1963@1|root,COG1963@2|Bacteria,2G6XC@200795|Chloroflexi	200795|Chloroflexi	S	Divergent PAP2 family	-	-	-	ko:K09775	-	-	-	-	ko00000	-	-	-	DUF212
REGS1_k127_4387019_1	926569.ANT_25910	3.14e-71	248.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	2|Bacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
REGS1_k127_4442648_13	665571.STHERM_c14960	2.317e-06	53.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4442648_9	330214.NIDE3890	2.829e-24	108.0	COG0723@1|root,COG0723@2|Bacteria,3J0TT@40117|Nitrospirae	40117|Nitrospirae	C	Rieske [2Fe-2S] domain	-	-	1.10.9.1	ko:K02636,ko:K03886	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00151,M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	-	Rieske
REGS1_k127_4442648_3	926554.KI912648_gene4944	1.589e-155	510.0	COG1164@1|root,COG1164@2|Bacteria,1WIRX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Oligoendopeptidase, pepF M3 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3,Peptidase_M3_N
REGS1_k127_4442648_0	926569.ANT_06270	6.584e-223	697.0	COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the Glu Leu Phe Val dehydrogenases family	-	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
REGS1_k127_4442648_2	926569.ANT_24690	5.788e-171	551.0	COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
REGS1_k127_4442648_4	751994.AGIG01000035_gene318	1.55e-84	293.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,1RMCP@1236|Gammaproteobacteria,1J4J6@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_1029,iECIAI39_1322.ECIAI39_2202,iECUMN_1333.ECUMN_1134,iEcSMS35_1347.EcSMS35_2174,iPC815.YPO1415,iYL1228.KPN_00974	DHO_dh
REGS1_k127_4442648_7	768706.Desor_3591	4.094e-29	123.0	COG2318@1|root,COG2318@2|Bacteria,1V51W@1239|Firmicutes	1239|Firmicutes	S	DinB family	dinB	-	-	-	-	-	-	-	-	-	-	-	DinB
REGS1_k127_4442648_1	1192034.CAP_3742	7.48e-214	672.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_4442648_14	1117379.BABA_07866	0.0001055	55.0	COG3258@1|root,COG3258@2|Bacteria,1W16W@1239|Firmicutes,4I68F@91061|Bacilli,1ZEIM@1386|Bacillus	91061|Bacilli	C	COG2010 Cytochrome c, mono- and diheme variants	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
REGS1_k127_4442648_10	234267.Acid_6208	1.348e-18	100.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3Y4F0@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_C,Cytochrome_B
REGS1_k127_4442648_5	330214.NIDE3889	7.021e-66	233.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3J0Q6@40117|Nitrospirae	2|Bacteria	C	Cytochrome b/b6/petB	qcrC	-	-	ko:K00412,ko:K03888	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B,Cytochrome_CBB3
REGS1_k127_4442648_8	234267.Acid_6209	1.316e-25	113.0	COG0723@1|root,COG0723@2|Bacteria,3Y7YJ@57723|Acidobacteria	57723|Acidobacteria	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03886	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
REGS1_k127_4442648_12	886293.Sinac_6655	4.49e-10	66.0	COG2009@1|root,COG2009@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	ko:K00241,ko:K00247	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
REGS1_k127_4481407_6	862751.SACTE_2228	4.051e-33	138.0	COG2203@1|root,COG2203@2|Bacteria,2I97I@201174|Actinobacteria	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2
REGS1_k127_4481407_4	1370125.AUWT01000032_gene1634	3.543e-87	295.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	Peptidase_S8
REGS1_k127_4481407_1	926550.CLDAP_39790	6.812e-210	668.0	COG1164@1|root,COG1164@2|Bacteria,2G5JB@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M3A and M3B, thimet oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
REGS1_k127_4481407_5	485913.Krac_8232	3.304e-33	147.0	COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi	200795|Chloroflexi	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4481407_11	227086.JGI_V11_91565	1.101e-05	58.0	COG0664@1|root,KOG0614@2759|Eukaryota	2759|Eukaryota	T	cGMP-dependent protein kinase activity	-	-	2.7.11.12	ko:K07376,ko:K19477	ko04022,ko04270,ko04540,ko04611,ko04713,ko04714,ko04730,ko04740,ko04923,ko04924,ko04970,map04022,map04270,map04540,map04611,map04713,map04714,map04730,map04740,map04923,map04924,map04970	M00694	-	-	ko00000,ko00001,ko00002,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_4481407_2	497964.CfE428DRAFT_0631	8.917e-169	563.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
REGS1_k127_4481407_12	479433.Caci_1095	0.0006466	48.0	COG2909@1|root,COG2909@2|Bacteria,2GM1B@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
REGS1_k127_4481407_10	2903.EOD35075	1.357e-06	52.0	COG1233@1|root,KOG4254@2759|Eukaryota	2759|Eukaryota	Q	all-trans-retinol 13,14-reductase activity	-	-	1.3.99.30	ko:K15745	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R07518,R09692	RC01214,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
REGS1_k127_4481407_9	694427.Palpr_0130	1.294e-16	85.0	COG1233@1|root,COG1233@2|Bacteria,4NF7K@976|Bacteroidetes,2FRUW@200643|Bacteroidia,22Y1X@171551|Porphyromonadaceae	976|Bacteroidetes	Q	Flavin containing amine oxidoreductase	-	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
REGS1_k127_4481407_3	314345.SPV1_07149	4.78e-103	353.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria	1224|Proteobacteria	FP	Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities	gppA	GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c42590,iECED1_1282.ECED1_4463,iECIAI39_1322.ECIAI39_2643	HD,Ppx-GppA
REGS1_k127_4481407_7	857087.Metme_0945	1.177e-32	140.0	COG5607@1|root,COG5607@2|Bacteria	2|Bacteria	F	PFAM CHAD domain containing protein	sixA-2	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	CHAD,His_Phos_1
REGS1_k127_4481407_8	1049564.TevJSym_ad00820	3.951e-23	105.0	COG2062@1|root,COG2062@2|Bacteria,1PKQU@1224|Proteobacteria,1TKA9@1236|Gammaproteobacteria,1J754@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
REGS1_k127_4481407_0	1183438.GKIL_2776	2.172e-210	672.0	COG0855@1|root,COG0855@2|Bacteria,1G1WA@1117|Cyanobacteria	1117|Cyanobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
REGS1_k127_4482017_0	926569.ANT_09720	2.566e-212	679.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
REGS1_k127_4482017_4	926569.ANT_09730	1.144e-58	211.0	COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi	200795|Chloroflexi	D	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization	minC	-	-	ko:K03610	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinC_C,MinC_N
REGS1_k127_4482017_2	926569.ANT_09740	1.742e-116	380.0	COG2894@1|root,COG2894@2|Bacteria,2G5YF@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the ParA family	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
REGS1_k127_4482017_5	592015.HMPREF1705_01323	2.749e-13	73.0	COG0851@1|root,COG0851@2|Bacteria,3TBIQ@508458|Synergistetes	508458|Synergistetes	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
REGS1_k127_4482017_3	926569.ANT_09760	9.214e-115	380.0	COG0772@1|root,COG0772@2|Bacteria,2G6GW@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
REGS1_k127_4482017_1	926569.ANT_09770	7.431e-191	604.0	COG0008@1|root,COG0008@2|Bacteria,2G5WU@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_4512600_0	926550.CLDAP_36980	1.826e-18	96.0	COG0845@1|root,COG0845@2|Bacteria,2G8X1@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
REGS1_k127_4512600_1	383372.Rcas_2709	2.125e-16	89.0	COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G8X1@200795|Chloroflexi,376YI@32061|Chloroflexia	32061|Chloroflexia	MV	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
REGS1_k127_4518603_0	211114.JOEF01000003_gene3012	1.798e-156	512.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4E8J5@85010|Pseudonocardiales	201174|Actinobacteria	E	FAD dependent oxidoreductase central domain	-	-	1.5.3.19	ko:K19191	ko00760,ko01120,map00760,map01120	-	R10102	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
REGS1_k127_4518603_1	1116369.KB890025_gene5283	1.893e-106	359.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2TSJ5@28211|Alphaproteobacteria,43GYK@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K00479	-	-	-	-	ko00000	-	-	-	Rieske,Ring_hydroxyl_A
REGS1_k127_4518603_2	41431.PCC8801_0885	7.317e-22	98.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.1.1.72,2.7.1.15,2.7.1.4	ko:K00571,ko:K00847,ko:K00852	ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100	-	R00760,R00867,R01051,R02750,R03920	RC00002,RC00017	ko00000,ko00001,ko01000,ko02048	-	-	-	PfkB
REGS1_k127_4534336_2	926569.ANT_08340	2.452e-37	143.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_4534336_0	926569.ANT_08350	1.749e-307	963.0	COG0243@1|root,COG1034@1|root,COG0243@2|Bacteria,COG1034@2|Bacteria	2|Bacteria	C	ATP synthesis coupled electron transport	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
REGS1_k127_4534336_1	926569.ANT_08360	4.507e-79	269.0	COG1005@1|root,COG1005@2|Bacteria,2G62Y@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
REGS1_k127_4535143_1	1408164.MOLA814_00698	5.658e-91	310.0	COG1216@1|root,COG1216@2|Bacteria,1PI1U@1224|Proteobacteria,2VI9D@28216|Betaproteobacteria,1KR4W@119066|unclassified Betaproteobacteria	2|Bacteria	S	overlaps another CDS with the same product name	wbbL_2	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
REGS1_k127_4535143_2	857087.Metme_1193	1.692e-50	192.0	COG1216@1|root,COG1216@2|Bacteria,1NG6M@1224|Proteobacteria,1S851@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Glycosyl transferase, family 2	wbbL	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glyco_transf_7C,Glycos_transf_2
REGS1_k127_4535143_0	1122176.KB903548_gene1179	4.273e-169	573.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,4NUFW@976|Bacteroidetes,1IZ0P@117747|Sphingobacteriia	976|Bacteroidetes	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
REGS1_k127_4539275_4	443144.GM21_4041	5.001e-09	68.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,43U5F@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ParB domain protein nuclease	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
REGS1_k127_4539275_1	1121468.AUBR01000078_gene859	4.636e-57	220.0	COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,25D02@186801|Clostridia,42FJ4@68295|Thermoanaerobacterales	186801|Clostridia	L	COGs COG4584 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Mu-transpos_C,rve
REGS1_k127_4539275_2	85643.Tmz1t_1082	3.239e-41	168.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2VMBN@28216|Betaproteobacteria,2KWWT@206389|Rhodocyclales	206389|Rhodocyclales	L	Bacterial dnaA  protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
REGS1_k127_4539275_0	439235.Dalk_2985	3.926e-62	223.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,2MM3S@213118|Desulfobacterales	28221|Deltaproteobacteria	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
REGS1_k127_4560793_3	926569.ANT_20910	1.631e-11	66.0	COG0324@1|root,COG0324@2|Bacteria,2G5S7@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
REGS1_k127_4560793_2	926569.ANT_20920	2.502e-24	106.0	COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi	200795|Chloroflexi	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
REGS1_k127_4560793_1	926569.ANT_20930	1.425e-78	278.0	COG0438@1|root,COG0438@2|Bacteria,2G61C@200795|Chloroflexi	200795|Chloroflexi	M	glycosyl transferase group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_4560793_5	639282.DEFDS_0603	0.0004207	45.0	COG2104@1|root,COG2104@2|Bacteria,2GG4W@200930|Deferribacteres	200930|Deferribacteres	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_4560793_0	1449080.JQMV01000003_gene1639	2.844e-89	303.0	COG0037@1|root,COG0037@2|Bacteria,1WIQC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	D	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	2.8.1.15	ko:K14058,ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
REGS1_k127_4560793_4	926550.CLDAP_20690	1.933e-06	52.0	COG0577@1|root,COG0577@2|Bacteria,2G6RX@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
REGS1_k127_4605201_0	393921.HQ45_00770	4.114e-08	58.0	COG0457@1|root,COG0642@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,COG2205@2|Bacteria,4NDXU@976|Bacteroidetes,2FMVV@200643|Bacteroidia,231SR@171551|Porphyromonadaceae	976|Bacteroidetes	T	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,PEPcase,Reg_prop,Response_reg,TPR_12,TPR_7,TPR_8,Y_Y_Y
REGS1_k127_4605201_1	547559.Nmag_2352	5.936e-07	57.0	COG1917@1|root,arCOG02999@2157|Archaea,2XZ6F@28890|Euryarchaeota,23WVC@183963|Halobacteria	183963|Halobacteria	S	PFAM Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_4605201_2	1408418.JNJH01000002_gene2890	0.0003809	48.0	COG0715@1|root,COG0715@2|Bacteria,1PI1C@1224|Proteobacteria,2V7PA@28211|Alphaproteobacteria,2JY77@204441|Rhodospirillales	204441|Rhodospirillales	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4625860_2	290317.Cpha266_0841	2.337e-200	635.0	COG1132@1|root,COG1132@2|Bacteria,1FD6W@1090|Chlorobi	1090|Chlorobi	P	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_4625860_1	290317.Cpha266_0842	7.498e-226	714.0	COG1132@1|root,COG1132@2|Bacteria	2|Bacteria	V	(ABC) transporter	yfiB	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_4625860_14	711393.AYRX01000033_gene37	2.665e-06	55.0	COG1846@1|root,COG1846@2|Bacteria,2IKZU@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
REGS1_k127_4625860_8	338966.Ppro_0727	1.758e-46	173.0	COG0655@1|root,COG0655@2|Bacteria,1N3NQ@1224|Proteobacteria,42TRR@68525|delta/epsilon subdivisions,2WQ13@28221|Deltaproteobacteria,43VWV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_4625860_7	696281.Desru_3228	6.063e-48	184.0	29Y33@1|root,30JW2@2|Bacteria,1W3SV@1239|Firmicutes,254NF@186801|Clostridia,266AP@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4625860_6	1234664.AMRO01000026_gene1207	9.201e-86	293.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli,1WF9Y@129337|Geobacillus	91061|Bacilli	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
REGS1_k127_4625860_9	1128421.JAGA01000002_gene1167	7.344e-46	170.0	COG0801@1|root,COG0801@2|Bacteria,2NPPF@2323|unclassified Bacteria	2|Bacteria	H	7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM0041	FolB,HPPK
REGS1_k127_4625860_15	1449069.JMLO01000033_gene12	0.0007193	49.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4FWJQ@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the thiolase family	fadA6_1	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_4625860_11	660470.Theba_1980	5.284e-37	149.0	COG0546@1|root,COG0546@2|Bacteria,2GE3E@200918|Thermotogae	200918|Thermotogae	S	PFAM haloacid	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
REGS1_k127_4625860_13	665959.HMPREF1013_03288	3.732e-12	73.0	COG2318@1|root,COG2318@2|Bacteria,1V95A@1239|Firmicutes,4IDNB@91061|Bacilli,1ZCII@1386|Bacillus	91061|Bacilli	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_4625860_4	404380.Gbem_1628	6.044e-104	360.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,42PUB@68525|delta/epsilon subdivisions,2WMH5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM type I phosphodiesterase nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
REGS1_k127_4625860_5	926569.ANT_10690	5.461e-97	323.0	COG1402@1|root,COG1402@2|Bacteria,2G7B0@200795|Chloroflexi	200795|Chloroflexi	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
REGS1_k127_4625860_0	926569.ANT_30500	0.0	1128.0	COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase, family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
REGS1_k127_4625860_12	926550.CLDAP_10960	1.235e-36	145.0	COG2030@1|root,COG2030@2|Bacteria,2G966@200795|Chloroflexi	200795|Chloroflexi	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
REGS1_k127_4636424_28	926569.ANT_15370	9.21e-25	111.0	COG2068@1|root,COG2068@2|Bacteria,2G6W9@200795|Chloroflexi	200795|Chloroflexi	S	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
REGS1_k127_4636424_14	926569.ANT_14520	4.615e-74	259.0	COG3608@1|root,COG3608@2|Bacteria,2G71G@200795|Chloroflexi	200795|Chloroflexi	S	succinylglutamate desuccinylase aspartoacylase	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_4636424_26	497964.CfE428DRAFT_3478	1.319e-36	149.0	COG4330@1|root,COG4330@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1361)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1361
REGS1_k127_4636424_13	439235.Dalk_1565	2.399e-74	262.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42P9B@68525|delta/epsilon subdivisions,2WMCP@28221|Deltaproteobacteria,2MMBX@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
REGS1_k127_4636424_0	926569.ANT_14510	6.074e-285	892.0	COG1529@1|root,COG1529@2|Bacteria,2G5PH@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
REGS1_k127_4636424_2	926569.ANT_14490	3.121e-165	533.0	COG1319@1|root,COG2080@1|root,COG1319@2|Bacteria,COG2080@2|Bacteria,2G5XD@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
REGS1_k127_4636424_21	926569.ANT_20600	1.133e-46	174.0	arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4636424_5	861299.J421_2874	2.294e-145	475.0	COG0191@1|root,COG0191@2|Bacteria,1ZSZE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	G	Fructose-bisphosphate aldolase class-II	-	-	-	-	-	-	-	-	-	-	-	-	F_bP_aldolase
REGS1_k127_4636424_25	926569.ANT_11610	1.873e-37	147.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.7.53,3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K13669,ko:K19710	ko00230,map00230	-	R00126,R01054,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000,ko01003,ko03400	-	GT87	-	GT87,NUDIX
REGS1_k127_4636424_11	926569.ANT_03540	1.593e-78	265.0	COG1839@1|root,COG1839@2|Bacteria,2G6BH@200795|Chloroflexi	200795|Chloroflexi	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
REGS1_k127_4636424_18	1380390.JIAT01000010_gene4351	5.677e-61	222.0	COG3511@1|root,COG3511@2|Bacteria,2II4P@201174|Actinobacteria	201174|Actinobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
REGS1_k127_4636424_17	926569.ANT_11620	3.123e-61	218.0	COG0742@1|root,COG0742@2|Bacteria,2G6Y8@200795|Chloroflexi	200795|Chloroflexi	L	Methyltransferase	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
REGS1_k127_4636424_7	926569.ANT_11630	8.034e-124	406.0	COG0407@1|root,COG0407@2|Bacteria,2G6BE@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
REGS1_k127_4636424_23	439235.Dalk_2449	1.719e-43	177.0	COG1807@1|root,COG1807@2|Bacteria,1NSSV@1224|Proteobacteria,42XJQ@68525|delta/epsilon subdivisions,2WSMN@28221|Deltaproteobacteria,2MP2F@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4636424_24	479434.Sthe_0091	1.695e-41	157.0	COG1607@1|root,COG1607@2|Bacteria,2G7A6@200795|Chloroflexi	200795|Chloroflexi	I	PFAM thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_4636424_22	926569.ANT_11660	1.861e-44	169.0	COG2246@1|root,COG2246@2|Bacteria,2G7BJ@200795|Chloroflexi	200795|Chloroflexi	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
REGS1_k127_4636424_4	926569.ANT_11670	9.307e-156	497.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_4636424_6	926569.ANT_11680	7.459e-141	464.0	COG0823@1|root,COG3583@1|root,COG0823@2|Bacteria,COG3583@2|Bacteria	2|Bacteria	S	pathogenesis	-	-	-	ko:K21471,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	G5,NLPC_P60,Peptidase_M26_C,YSIRK_signal
REGS1_k127_4636424_19	926569.ANT_11700	3.646e-57	204.0	COG1386@1|root,COG1386@2|Bacteria,2G6V6@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
REGS1_k127_4636424_8	926569.ANT_11710	1.688e-90	304.0	COG1187@1|root,COG1187@2|Bacteria,2G6HU@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.20,5.4.99.22	ko:K06178,ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_4636424_1	926569.ANT_19690	3.066e-205	650.0	COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M20	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_4636424_20	926569.ANT_19700	1.641e-51	188.0	COG1238@1|root,COG1238@2|Bacteria,2G932@200795|Chloroflexi	200795|Chloroflexi	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_4636424_16	1128421.JAGA01000002_gene981	1.579e-70	244.0	COG0652@1|root,COG0652@2|Bacteria,2NPSW@2323|unclassified Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
REGS1_k127_4636424_10	926569.ANT_19710	1.101e-83	283.0	COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi	200795|Chloroflexi	F	Cytidine monophosphokinase	udk	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
REGS1_k127_4636424_9	926569.ANT_22980	2.92e-90	305.0	COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM DegV family protein	-	-	-	-	-	-	-	-	-	-	-	-	DegV
REGS1_k127_4636424_3	926569.ANT_09690	2.54e-159	509.0	COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi	200795|Chloroflexi	D	TIGRFAM cell shape determining protein, MreB Mrl family	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
REGS1_k127_4636424_12	926569.ANT_09700	5.696e-78	269.0	COG1792@1|root,COG1792@2|Bacteria,2G743@200795|Chloroflexi	200795|Chloroflexi	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
REGS1_k127_4636424_15	926569.ANT_09720	4.594e-72	259.0	COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi	200795|Chloroflexi	M	PFAM penicillin-binding protein transpeptidase	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
REGS1_k127_4637415_2	1170562.Cal6303_2580	1.052e-06	51.0	COG0477@1|root,COG0477@2|Bacteria,1G174@1117|Cyanobacteria,1HRAE@1161|Nostocales	1117|Cyanobacteria	EGP	Transmembrane secretion effector	-	-	-	ko:K07785	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.1.31	-	-	MFS_1
REGS1_k127_4637415_0	335543.Sfum_1461	1.349e-97	328.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,2MQWV@213462|Syntrophobacterales	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
REGS1_k127_4637415_1	279714.FuraDRAFT_2138	2.804e-89	312.0	COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,2VKTY@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
REGS1_k127_464988_0	204669.Acid345_3016	3.624e-172	550.0	COG0531@1|root,COG0531@2|Bacteria,3Y3GY@57723|Acidobacteria,2JHIT@204432|Acidobacteriia	204432|Acidobacteriia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease
REGS1_k127_464988_1	234267.Acid_7527	2.662e-102	339.0	COG3250@1|root,COG3250@2|Bacteria,3Y2PR@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.165	ko:K15855	ko00520,ko01100,map00520,map01100	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2
REGS1_k127_4653384_0	926550.CLDAP_11260	1.599e-140	459.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
REGS1_k127_4653384_1	867845.KI911784_gene1086	5.146e-129	420.0	COG1132@1|root,COG1132@2|Bacteria,2G7J5@200795|Chloroflexi,3758C@32061|Chloroflexia	32061|Chloroflexia	V	PFAM ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_4653844_1	1379698.RBG1_1C00001G0857	3.622e-82	298.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4653844_3	929556.Solca_2233	1.241e-51	206.0	COG0437@1|root,COG0437@2|Bacteria,4NI8R@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
REGS1_k127_4653844_5	1380390.JIAT01000010_gene3975	0.0006895	50.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
REGS1_k127_4653844_4	204773.HEAR1641	0.000372	51.0	COG2010@1|root,COG2010@2|Bacteria,1MUCW@1224|Proteobacteria,2VHGS@28216|Betaproteobacteria,4726F@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex	ccoP	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
REGS1_k127_4653844_2	105559.Nwat_1866	2.834e-75	259.0	COG0432@1|root,COG0432@2|Bacteria,1RA5G@1224|Proteobacteria,1S3N1@1236|Gammaproteobacteria,1X23J@135613|Chromatiales	135613|Chromatiales	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
REGS1_k127_4653844_0	518766.Rmar_0492	8.113e-109	359.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,1FJPN@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
REGS1_k127_4670987_4	1123284.KB899046_gene2246	7.506e-05	50.0	COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli,26P7K@186821|Sporolactobacillaceae	91061|Bacilli	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
REGS1_k127_4670987_2	1041930.Mtc_0244	3.897e-74	258.0	COG1131@1|root,arCOG00194@2157|Archaea,2XUK9@28890|Euryarchaeota,2N95K@224756|Methanomicrobia	224756|Methanomicrobia	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_4670987_3	1173028.ANKO01000193_gene5867	1.142e-64	237.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria	1117|Cyanobacteria	KLT	Serine Threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,WD40
REGS1_k127_4670987_0	316274.Haur_3631	2.923e-102	343.0	COG3868@1|root,COG3868@2|Bacteria,2G7U5@200795|Chloroflexi,3775X@32061|Chloroflexia	32061|Chloroflexia	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
REGS1_k127_4670987_1	1299327.I546_5504	4.277e-80	273.0	COG0778@1|root,COG0778@2|Bacteria,2GM9M@201174|Actinobacteria,235BZ@1762|Mycobacteriaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_4676342_8	1480694.DC28_12360	3.216e-75	263.0	COG1175@1|root,COG1175@2|Bacteria,2J5SW@203691|Spirochaetes	203691|Spirochaetes	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10233	ko02010,map02010	M00201,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.32,3.A.1.1.8	-	-	BPD_transp_1
REGS1_k127_4676342_1	1280390.CBQR020000054_gene1064	9.316e-169	542.0	COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes,4HT5T@91061|Bacilli,26RVV@186822|Paenibacillaceae	91061|Bacilli	G	ABC transporter substrate-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
REGS1_k127_4676342_7	326427.Cagg_1685	2.431e-79	276.0	COG1609@1|root,COG1609@2|Bacteria,2G6DT@200795|Chloroflexi,376ZH@32061|Chloroflexia	32061|Chloroflexia	K	periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
REGS1_k127_4676342_6	926569.ANT_14920	7.831e-80	271.0	COG3000@1|root,COG3000@2|Bacteria	2|Bacteria	I	iron ion binding	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
REGS1_k127_4676342_2	926550.CLDAP_01130	2.807e-167	545.0	COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
REGS1_k127_4676342_9	926569.ANT_29880	8.012e-56	199.0	COG0782@1|root,COG0782@2|Bacteria,2G6U9@200795|Chloroflexi	200795|Chloroflexi	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_4676342_10	926569.ANT_00330	2.815e-43	168.0	COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM LmbE family protein	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
REGS1_k127_4676342_5	926550.CLDAP_22240	5.433e-117	396.0	COG1215@1|root,COG1215@2|Bacteria,2G952@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glyco_tranf_2_3,T2SSE_N
REGS1_k127_4676342_3	926569.ANT_24830	7.701e-162	521.0	COG2230@1|root,COG2230@2|Bacteria,2G8QA@200795|Chloroflexi	200795|Chloroflexi	H	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
REGS1_k127_4676342_0	1128421.JAGA01000003_gene2953	0.0	1032.0	COG0366@1|root,COG0366@2|Bacteria,2NQQN@2323|unclassified Bacteria	2|Bacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
REGS1_k127_4676342_11	1036674.A28LD_1242	1.395e-27	113.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,1SCA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_4676342_4	1521187.JPIM01000001_gene834	4.876e-158	506.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	yghO	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_4676342_12	479433.Caci_8266	1.017e-07	57.0	COG3104@1|root,COG3104@2|Bacteria,2I63Y@201174|Actinobacteria	201174|Actinobacteria	E	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_4684878_3	926550.CLDAP_20840	2.513e-49	178.0	COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
REGS1_k127_4684878_8	667014.Thein_1747	2.939e-30	122.0	COG2827@1|root,COG2827@2|Bacteria	2|Bacteria	L	Endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
REGS1_k127_4684878_7	1173026.Glo7428_1565	7.529e-35	144.0	COG1670@1|root,COG1670@2|Bacteria,1G6BV@1117|Cyanobacteria	1117|Cyanobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
REGS1_k127_4684878_1	926569.ANT_02480	1.492e-73	256.0	COG0290@1|root,COG0290@2|Bacteria,2G6N2@200795|Chloroflexi	200795|Chloroflexi	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
REGS1_k127_4684878_9	926569.ANT_00600	4.156e-24	103.0	COG0291@1|root,COG0291@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
REGS1_k127_4684878_4	926569.ANT_00590	9.055e-47	170.0	COG0292@1|root,COG0292@2|Bacteria,2G6V4@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
REGS1_k127_4684878_5	688269.Theth_1877	1.112e-41	161.0	COG2110@1|root,COG2110@2|Bacteria,2GD2K@200918|Thermotogae	200918|Thermotogae	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
REGS1_k127_4684878_6	240292.Ava_0352	4.871e-35	139.0	29WKC@1|root,30I6W@2|Bacteria,1GDBN@1117|Cyanobacteria,1HNA1@1161|Nostocales	1117|Cyanobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
REGS1_k127_4684878_2	926569.ANT_26460	3.131e-65	233.0	COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
REGS1_k127_4684878_0	395961.Cyan7425_4809	9.61e-82	280.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,3KGBC@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_4714118_1	330214.NIDE4289	1.553e-45	169.0	COG2732@1|root,COG2732@2|Bacteria	2|Bacteria	K	(Barnase) inhibitor	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
REGS1_k127_4714118_2	330214.NIDE4288	3.339e-27	116.0	COG4290@1|root,COG4290@2|Bacteria	2|Bacteria	F	endoribonuclease activity	-	GO:0005575,GO:0005576	-	ko:K03628,ko:K15125	ko03018,ko05133,map03018,map05133	-	-	-	ko00000,ko00001,ko00536,ko03019,ko03021	-	-	-	Ribonuclease
REGS1_k127_4714118_0	330214.NIDE4287	4.96e-248	777.0	COG0205@1|root,COG0406@1|root,COG0205@2|Bacteria,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	pfkA	-	2.7.1.11,2.7.1.90	ko:K00850,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R00764,R02073,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	His_Phos_1,PFK
REGS1_k127_4761167_4	316274.Haur_2761	7.33e-174	562.0	COG0477@1|root,COG0477@2|Bacteria,2G856@200795|Chloroflexi,375QC@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_4761167_1	926569.ANT_04080	3.116e-272	848.0	COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi	200795|Chloroflexi	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
REGS1_k127_4761167_15	1144305.PMI02_02984	1.108e-09	70.0	2CIPC@1|root,2Z9HB@2|Bacteria,1R3W8@1224|Proteobacteria,2TST7@28211|Alphaproteobacteria,2K56C@204457|Sphingomonadales	204457|Sphingomonadales	S	Glycosyltransferase family 87	-	-	-	-	-	-	-	-	-	-	-	-	GT87
REGS1_k127_4761167_13	926569.ANT_04110	1.218e-40	158.0	COG1399@1|root,COG1399@2|Bacteria	2|Bacteria	K	metal-binding, possibly nucleic acid-binding protein	yceD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
REGS1_k127_4761167_7	926569.ANT_14700	1.031e-109	364.0	COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	hepT	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_4761167_11	926550.CLDAP_39380	2.461e-65	233.0	COG0084@1|root,COG0084@2|Bacteria,2G6F2@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
REGS1_k127_4761167_2	926569.ANT_14720	3.217e-215	678.0	COG1109@1|root,COG1109@2|Bacteria,2G5Y4@200795|Chloroflexi	200795|Chloroflexi	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_4761167_6	926569.ANT_14730	1.83e-131	431.0	COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi	200795|Chloroflexi	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
REGS1_k127_4761167_5	926569.ANT_14740	1.537e-132	431.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
REGS1_k127_4761167_9	926569.ANT_30870	7.062e-85	286.0	COG0586@1|root,COG0586@2|Bacteria,2G79V@200795|Chloroflexi	200795|Chloroflexi	S	SNARE associated Golgi protein	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
REGS1_k127_4761167_3	926550.CLDAP_18930	2.779e-180	575.0	COG0017@1|root,COG0017@2|Bacteria,2G6PN@200795|Chloroflexi	200795|Chloroflexi	J	tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
REGS1_k127_4761167_0	926569.ANT_12650	9.194e-280	870.0	COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi	200795|Chloroflexi	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
REGS1_k127_4761167_8	926569.ANT_15400	8.518e-97	326.0	COG0667@1|root,COG0667@2|Bacteria,2G6QZ@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_4761167_10	926569.ANT_22460	4.156e-81	277.0	COG0571@1|root,COG0571@2|Bacteria,2G6PD@200795|Chloroflexi	200795|Chloroflexi	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
REGS1_k127_4761167_12	926569.ANT_22450	3.716e-44	163.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
REGS1_k127_4772448_16	880526.KE386488_gene1778	6.061e-34	133.0	COG1917@1|root,COG1917@2|Bacteria,4NSB6@976|Bacteroidetes,2FT3R@200643|Bacteroidia,22VFI@171550|Rikenellaceae	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_4772448_3	926569.ANT_29200	1.075e-220	704.0	COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi	200795|Chloroflexi	S	Immune inhibitor A peptidase M6	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M6
REGS1_k127_4772448_0	926569.ANT_04140	0.0	1286.0	COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi	200795|Chloroflexi	O	ATPase associated with various cellular activities, AAA_5	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_4772448_12	926569.ANT_04150	1.137e-52	201.0	COG0454@1|root,COG0456@2|Bacteria,2G9GA@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_4772448_18	926569.ANT_04160	5.791e-25	111.0	COG1950@1|root,COG1950@2|Bacteria,2G7E6@200795|Chloroflexi	200795|Chloroflexi	S	PFAM membrane protein of	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
REGS1_k127_4772448_9	1304880.JAGB01000002_gene1805	1.827e-105	351.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,24AVR@186801|Clostridia	186801|Clostridia	EQ	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
REGS1_k127_4772448_10	926569.ANT_14100	4.676e-93	319.0	COG0628@1|root,COG0628@2|Bacteria,2G6TV@200795|Chloroflexi	200795|Chloroflexi	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_4772448_17	926569.ANT_14090	3.224e-27	119.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
REGS1_k127_4772448_13	1157490.EL26_15670	1.286e-46	177.0	COG0321@1|root,COG0321@2|Bacteria,1V44P@1239|Firmicutes,4HH4H@91061|Bacilli,279KG@186823|Alicyclobacillaceae	91061|Bacilli	H	Biotin/lipoate A/B protein ligase family	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
REGS1_k127_4772448_21	1121378.KB899728_gene4132	4.321e-10	62.0	COG1249@1|root,COG1249@2|Bacteria,1WI3A@1297|Deinococcus-Thermus	2|Bacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)	sthA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_4772448_6	1303518.CCALI_01587	4.578e-138	456.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	dprE1	GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576	1.1.3.8,1.1.98.3	ko:K00103,ko:K16653	ko00053,ko01100,map00053,map01100	M00129	R00647,R03184,R10053	RC00195,RC00346,RC00869	ko00000,ko00001,ko00002,ko01000	-	-	-	ALO,FAD_binding_4
REGS1_k127_4772448_11	1192034.CAP_3530	5.75e-63	225.0	COG0300@1|root,COG0300@2|Bacteria,1NGXF@1224|Proteobacteria,42Q5Q@68525|delta/epsilon subdivisions,2WNMS@28221|Deltaproteobacteria,2YV1C@29|Myxococcales	28221|Deltaproteobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,adh_short
REGS1_k127_4772448_2	1128421.JAGA01000002_gene557	7.734e-262	816.0	COG2866@1|root,COG2866@2|Bacteria,2NPI7@2323|unclassified Bacteria	2|Bacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
REGS1_k127_4772448_14	358681.BBR47_44360	3.106e-41	154.0	COG0662@1|root,COG0662@2|Bacteria,1V7K2@1239|Firmicutes,4HN60@91061|Bacilli,26WT8@186822|Paenibacillaceae	91061|Bacilli	G	Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_4772448_4	926569.ANT_01770	1.298e-155	500.0	COG0438@1|root,COG0438@2|Bacteria,2G6KX@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
REGS1_k127_4772448_5	926569.ANT_01740	7.788e-148	491.0	COG5360@1|root,COG5360@2|Bacteria	2|Bacteria	S	Heparinase II/III-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Hepar_II_III,Hepar_II_III_N
REGS1_k127_4772448_1	926569.ANT_30270	1.312e-269	848.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,2G75J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_4772448_7	926569.ANT_29410	4.165e-135	440.0	COG2309@1|root,COG2309@2|Bacteria,2G62B@200795|Chloroflexi	200795|Chloroflexi	E	peptidase M29 aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
REGS1_k127_4772448_20	57918.XP_004291731.1	4.017e-17	85.0	COG0476@1|root,KOG2017@2759|Eukaryota,37JB8@33090|Viridiplantae,3G8N0@35493|Streptophyta,4JFWN@91835|fabids	35493|Streptophyta	H	rhodanese-like PpiC domain-containing protein	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009719,GO:0009725,GO:0009735,GO:0010033,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050896	-	-	-	-	-	-	-	-	-	-	Rhodanese,Rotamase_3
REGS1_k127_4772448_15	350688.Clos_0555	1.209e-35	143.0	COG4843@1|root,COG4843@2|Bacteria,1V14J@1239|Firmicutes,24J7S@186801|Clostridia,36IGD@31979|Clostridiaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
REGS1_k127_4772448_8	926569.ANT_05040	4.21e-125	406.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
REGS1_k127_4783158_2	926569.ANT_23150	2.732e-52	190.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_4783158_3	1123389.ATXJ01000003_gene331	3.338e-33	133.0	COG4319@1|root,COG4319@2|Bacteria,1WJSX@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM Calcium calmodulin dependent protein kinase II	-	-	-	-	-	-	-	-	-	-	-	-	CaMKII_AD
REGS1_k127_4783158_0	926569.ANT_02410	1.129e-91	314.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pelF	-	-	ko:K21011,ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glyco_trans_1_4,Glycos_transf_1
REGS1_k127_4783158_1	926569.ANT_31760	6.615e-90	302.0	COG1428@1|root,COG1428@2|Bacteria	2|Bacteria	F	Deoxynucleoside kinase	dgk	-	2.7.1.113	ko:K15518	ko00230,map00230	-	R01967	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	HPPK,dNK
REGS1_k127_4789614_4	926569.ANT_00530	3.072e-52	188.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
REGS1_k127_4789614_7	926569.ANT_00520	1.937e-32	132.0	COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi	200795|Chloroflexi	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	zf-B_box
REGS1_k127_4789614_1	926569.ANT_00510	5.582e-90	305.0	COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi	200795|Chloroflexi	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
REGS1_k127_4789614_2	926569.ANT_06250	1.782e-53	192.0	COG1468@1|root,COG1468@2|Bacteria,2G6VA@200795|Chloroflexi	200795|Chloroflexi	L	Domain of unknown function DUF83	-	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
REGS1_k127_4789614_3	1227360.C176_00815	2.163e-53	195.0	COG1413@1|root,COG1413@2|Bacteria,1VTQX@1239|Firmicutes,4HTH7@91061|Bacilli	91061|Bacilli	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4789614_5	1116369.KB890024_gene4140	1.174e-44	177.0	COG1680@1|root,COG1680@2|Bacteria,1MY01@1224|Proteobacteria,2U35E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF3471
REGS1_k127_4789614_6	1192034.CAP_7043	6.769e-43	172.0	2C4HX@1|root,2Z9XP@2|Bacteria,1MY22@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4789614_0	1121377.KB906402_gene3271	1.597e-110	368.0	COG0747@1|root,COG0747@2|Bacteria,1WIYQ@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_478977_10	237368.SCABRO_01358	1.761e-11	66.0	COG1682@1|root,COG1682@2|Bacteria,2IYXC@203682|Planctomycetes	203682|Planctomycetes	U	COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
REGS1_k127_478977_8	926569.ANT_06280	6.988e-19	93.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	DUF4388,HTH_24,MarR_2
REGS1_k127_478977_5	1047013.AQSP01000144_gene899	1.006e-67	241.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
REGS1_k127_478977_9	56780.SYN_02355	4.981e-12	74.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
REGS1_k127_478977_1	43989.cce_1406	1.078e-161	519.0	COG0399@1|root,COG0399@2|Bacteria,1G0XH@1117|Cyanobacteria,3KH3K@43988|Cyanothece	1117|Cyanobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_478977_7	118163.Ple7327_1392	3.563e-56	199.0	2BWTW@1|root,315N7@2|Bacteria,1G5TV@1117|Cyanobacteria,3VMQC@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_478977_11	1111479.AXAR01000002_gene1961	1.278e-09	70.0	COG1807@1|root,COG1807@2|Bacteria,1V114@1239|Firmicutes,4HB64@91061|Bacilli	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_478977_0	596151.DesfrDRAFT_0632	2.498e-187	609.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2M88F@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
REGS1_k127_478977_4	573370.DMR_42770	4.125e-97	330.0	COG0438@1|root,COG0438@2|Bacteria,1RH5W@1224|Proteobacteria,42UY3@68525|delta/epsilon subdivisions,2WQ9B@28221|Deltaproteobacteria,2MA2D@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_478977_6	926569.ANT_06160	5.139e-58	213.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
REGS1_k127_478977_2	926569.ANT_06170	1.421e-138	447.0	COG0463@1|root,COG0463@2|Bacteria,2G5X5@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_4802112_0	926569.ANT_28860	3.463e-201	642.0	COG1198@1|root,COG1198@2|Bacteria,2G60J@200795|Chloroflexi	200795|Chloroflexi	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
REGS1_k127_4802112_12	304371.MCP_2443	3.499e-21	105.0	arCOG08211@1|root,arCOG08211@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4802112_9	926569.ANT_01450	8.114e-68	234.0	COG2236@1|root,COG2236@2|Bacteria,2G6Y5@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
REGS1_k127_4802112_2	926569.ANT_23160	2.047e-175	582.0	COG0419@1|root,COG0419@2|Bacteria,2G682@200795|Chloroflexi	200795|Chloroflexi	L	PFAM SMC domain protein	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,Rad50_zn_hook,SbcCD_C
REGS1_k127_4802112_6	926569.ANT_05520	1.333e-121	400.0	COG1363@1|root,COG1363@2|Bacteria,2G5WS@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
REGS1_k127_4802112_5	926569.ANT_05530	2.15e-125	412.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
REGS1_k127_4802112_10	926569.ANT_25530	1.305e-34	143.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
REGS1_k127_4802112_3	926569.ANT_05540	2.028e-136	443.0	COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi	200795|Chloroflexi	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
REGS1_k127_4802112_11	926569.ANT_23620	1.349e-25	113.0	COG2839@1|root,COG2839@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF456)	yqgC	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
REGS1_k127_4802112_1	926569.ANT_23610	1.804e-190	606.0	COG0172@1|root,COG0172@2|Bacteria,2G5PD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
REGS1_k127_4802112_8	926569.ANT_01070	2.586e-81	274.0	COG2148@1|root,COG2148@2|Bacteria,2G7P3@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
REGS1_k127_4802112_7	926569.ANT_28720	1.193e-113	371.0	COG0745@1|root,COG0745@2|Bacteria,2G5TG@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07669	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_4802112_4	926569.ANT_28730	2.603e-135	447.0	COG2770@1|root,COG5002@1|root,COG2770@2|Bacteria,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_4802112_13	870187.Thini_1990	2.073e-11	72.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,1S8R3@1236|Gammaproteobacteria,460FY@72273|Thiotrichales	72273|Thiotrichales	M	PFAM Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,SLT
REGS1_k127_4804582_2	105425.BBPL01000029_gene3936	9.083e-22	101.0	29BBV@1|root,2ZYA6@2|Bacteria,2ICWN@201174|Actinobacteria,2NG4P@228398|Streptacidiphilus	201174|Actinobacteria	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
REGS1_k127_4804582_0	589865.DaAHT2_0700	2.451e-109	372.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2MPI2@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
REGS1_k127_4804582_1	56780.SYN_02059	7.291e-48	179.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MQHV@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
REGS1_k127_4806246_1	926569.ANT_22620	7.43e-121	398.0	COG1086@1|root,COG1086@2|Bacteria,2G5M8@200795|Chloroflexi	200795|Chloroflexi	GM	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
REGS1_k127_4806246_3	246194.CHY_1057	1.487e-78	273.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,25EDZ@186801|Clostridia,42JFW@68295|Thermoanaerobacterales	186801|Clostridia	M	RmlD substrate binding domain	-	-	4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7	ko:K01784,ko:K02473,ko:K03274,ko:K08678	ko00052,ko00520,ko00540,ko01100,map00052,map00520,map00540,map01100	M00064,M00361,M00362,M00632	R00291,R00418,R01384,R02984,R05176	RC00289,RC00508,RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,GDP_Man_Dehyd
REGS1_k127_4806246_0	926569.ANT_22630	1.4e-134	445.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G6DJ@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
REGS1_k127_4806246_2	926569.ANT_22640	5.797e-118	389.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wblJ	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
REGS1_k127_4806246_5	1254432.SCE1572_26460	0.0001846	44.0	COG1196@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CHASE3,CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_4806246_4	401526.TcarDRAFT_0666	1.375e-42	160.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4H4UD@909932|Negativicutes	909932|Negativicutes	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
REGS1_k127_4823129_1	246197.MXAN_0784	8.736e-25	104.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
REGS1_k127_4823129_3	398578.Daci_1508	0.0003204	50.0	COG0745@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3829@1|root,COG4251@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1NC9X@1224|Proteobacteria,2WGIN@28216|Betaproteobacteria,4AJX3@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_4823129_0	234267.Acid_2646	2.135e-81	278.0	COG2834@1|root,COG2834@2|Bacteria,3Y7NW@57723|Acidobacteria	57723|Acidobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4823129_2	234267.Acid_2647	1.234e-07	56.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,3Y6ZR@57723|Acidobacteria	57723|Acidobacteria	M	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
REGS1_k127_4824396_2	926569.ANT_18490	2.969e-59	207.0	COG0785@1|root,COG0785@2|Bacteria,2G6V3@200795|Chloroflexi	200795|Chloroflexi	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
REGS1_k127_4824396_0	926569.ANT_18470	4.866e-86	295.0	COG0625@1|root,COG3815@1|root,COG0625@2|Bacteria,COG3815@2|Bacteria,2G73B@200795|Chloroflexi	200795|Chloroflexi	O	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
REGS1_k127_4824396_1	926569.ANT_18460	4.625e-69	243.0	COG1496@1|root,COG1496@2|Bacteria,2G6N5@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
REGS1_k127_4824396_3	1415756.JQMY01000001_gene279	3.315e-07	56.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2TR5Z@28211|Alphaproteobacteria,2PDCP@252301|Oceanicola	28211|Alphaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
REGS1_k127_4824848_2	485913.Krac_9623	2.32e-134	436.0	COG0258@1|root,COG0258@2|Bacteria	2|Bacteria	L	nuclease activity	polA	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
REGS1_k127_4824848_3	526227.Mesil_0712	1.263e-120	402.0	COG1167@1|root,COG1167@2|Bacteria,1WI0K@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
REGS1_k127_4824848_0	926550.CLDAP_03390	1.256e-211	676.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2G5X6@200795|Chloroflexi	200795|Chloroflexi	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Nitrate_red_gam
REGS1_k127_4824848_4	926569.ANT_19390	9.474e-58	203.0	COG0755@1|root,COG0755@2|Bacteria,2G6SI@200795|Chloroflexi	200795|Chloroflexi	O	PFAM Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
REGS1_k127_4848635_2	926569.ANT_19420	8.039e-66	243.0	COG2010@1|root,COG2010@2|Bacteria,2G741@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cytochrome_CBB3
REGS1_k127_4848635_8	926569.ANT_19430	2.772e-25	111.0	2DRD8@1|root,33BA3@2|Bacteria,2G7EV@200795|Chloroflexi	200795|Chloroflexi	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
REGS1_k127_4848635_5	926550.CLDAP_40040	3.446e-45	171.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
REGS1_k127_4848635_6	926569.ANT_19460	2.311e-40	158.0	COG3088@1|root,COG3088@2|Bacteria,2G72W@200795|Chloroflexi	200795|Chloroflexi	O	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
REGS1_k127_4848635_1	671143.DAMO_1588	2.373e-160	528.0	COG1138@1|root,COG1138@2|Bacteria,2NNYV@2323|unclassified Bacteria	2|Bacteria	O	Cytochrome C assembly protein	ccmF	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564	-	ko:K02198,ko:K04016	-	-	R05712	RC00176	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
REGS1_k127_4848635_3	926569.ANT_19490	5.325e-65	226.0	COG2332@1|root,COG2332@2|Bacteria,2G7CS@200795|Chloroflexi	200795|Chloroflexi	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	-	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
REGS1_k127_4848635_4	1382306.JNIM01000001_gene1045	8.875e-54	196.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi	200795|Chloroflexi	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_4848635_7	309801.trd_1817	4.697e-37	158.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G7ZR@200795|Chloroflexi,27YV8@189775|Thermomicrobia	189775|Thermomicrobia	T	Histidine kinase	-	-	2.7.13.3	ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
REGS1_k127_4848635_0	926569.ANT_21930	1.005e-204	659.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	3.2.1.81,3.2.1.97	ko:K01219,ko:K17624	-	-	-	-	ko00000,ko01000	-	GH101	-	Big_2,CBM_6,Cytochrome_C7,F5_F8_type_C,Glyco_hyd_101C,Glyco_hydro_101,WxL
REGS1_k127_4869956_2	247490.KSU1_D1051	1.024e-20	93.0	COG2317@1|root,COG2317@2|Bacteria,2IXSU@203682|Planctomycetes	203682|Planctomycetes	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
REGS1_k127_4869956_1	379731.PST_0581	1.125e-72	254.0	COG1484@1|root,COG1484@2|Bacteria,1MVU2@1224|Proteobacteria,1RNUA@1236|Gammaproteobacteria,1Z0CJ@136846|Pseudomonas stutzeri group	1236|Gammaproteobacteria	L	ISPsy14, transposition helper protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
REGS1_k127_4869956_0	351348.Maqu_3187	1.095e-176	568.0	COG2771@1|root,COG4584@1|root,COG2771@2|Bacteria,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria,46A5W@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	PFAM Integrase, catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_24,rve
REGS1_k127_4869956_3	1085623.GNIT_2596	8.369e-05	49.0	COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria,465X7@72275|Alteromonadaceae	1236|Gammaproteobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,GDE_C
REGS1_k127_4870063_1	1487921.DP68_06660	2.879e-23	111.0	2ET8I@1|root,3147J@2|Bacteria,1USUA@1239|Firmicutes,24ZT1@186801|Clostridia,36QDI@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4870063_0	926569.ANT_15080	2.104e-25	119.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
REGS1_k127_4919177_4	1380370.JIBA01000010_gene2364	2.525e-77	263.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FFZ1@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_4919177_1	1535287.JP74_09390	2.559e-109	361.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,2TTDX@28211|Alphaproteobacteria,3N7PV@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function DUF58	MA20_44650	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_4919177_2	987059.RBXJA2T_01620	6.893e-82	283.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,1KKCR@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
REGS1_k127_4919177_3	675635.Psed_0414	2.318e-77	271.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DYPB@85010|Pseudonocardiales	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA,VWA_2
REGS1_k127_4919177_0	1121920.AUAU01000020_gene2550	2.145e-205	650.0	COG0433@1|root,COG0433@2|Bacteria,3Y69X@57723|Acidobacteria	57723|Acidobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	-	-	-	-	-	-	-	-	-	DUF853
REGS1_k127_4919177_6	1230343.CANP01000029_gene2273	5.486e-41	156.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,1SBIG@1236|Gammaproteobacteria,1JGNB@118969|Legionellales	118969|Legionellales	G	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_4919177_5	648996.Theam_1507	4.277e-41	154.0	COG3743@1|root,COG3743@2|Bacteria,2G52I@200783|Aquificae	200783|Aquificae	S	Domain of unknown function (DUF4332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
REGS1_k127_492887_1	926569.ANT_04320	1.1e-120	392.0	COG0491@1|root,COG0491@2|Bacteria,2G8XN@200795|Chloroflexi	200795|Chloroflexi	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_492887_0	926569.ANT_12970	5.736e-170	545.0	COG0323@1|root,COG0323@2|Bacteria,2G5XU@200795|Chloroflexi	200795|Chloroflexi	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
REGS1_k127_4967876_19	926569.ANT_17280	4.241e-13	69.0	COG1028@1|root,COG1028@2|Bacteria,2G8P1@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.104	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R01404,R04430,R04725,R04956,R04959,R04962,R04967,R04970	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_4967876_3	926569.ANT_17290	9.586e-121	407.0	COG2843@1|root,COG2843@2|Bacteria,2G78I@200795|Chloroflexi	200795|Chloroflexi	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
REGS1_k127_4967876_2	383372.Rcas_2438	2.178e-129	422.0	COG4948@1|root,COG4948@2|Bacteria,2G704@200795|Chloroflexi,3771P@32061|Chloroflexia	32061|Chloroflexia	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
REGS1_k127_4967876_10	926569.ANT_14000	1.422e-63	222.0	COG1933@1|root,COG1933@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease I activity	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DZR,PLDc_N,zf-ribbon_3,zinc_ribbon_2
REGS1_k127_4967876_1	867845.KI911784_gene1240	1.194e-195	621.0	COG1027@1|root,COG1027@2|Bacteria,2G5IV@200795|Chloroflexi,37644@32061|Chloroflexia	32061|Chloroflexia	C	PFAM fumarate lyase	-	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
REGS1_k127_4967876_11	926569.ANT_23510	2.201e-53	205.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
REGS1_k127_4967876_5	926569.ANT_00310	4.806e-90	313.0	COG0651@1|root,COG0651@2|Bacteria,2G9I2@200795|Chloroflexi	200795|Chloroflexi	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
REGS1_k127_4967876_9	926569.ANT_25090	1.546e-67	244.0	COG4942@1|root,COG4942@2|Bacteria,2G960@200795|Chloroflexi	200795|Chloroflexi	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4967876_0	926569.ANT_25100	1.354e-213	682.0	COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi	200795|Chloroflexi	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
REGS1_k127_4967876_8	251229.Chro_4000	6.442e-68	237.0	COG2135@1|root,COG2135@2|Bacteria,1G1SA@1117|Cyanobacteria,3VK4S@52604|Pleurocapsales	1117|Cyanobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
REGS1_k127_4967876_4	926569.ANT_07430	5.651e-94	322.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi	200795|Chloroflexi	M	Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23,SH3_3
REGS1_k127_4967876_15	1254432.SCE1572_05510	5.523e-35	145.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_4967876_13	1382356.JQMP01000003_gene1897	7.073e-45	168.0	COG3358@1|root,COG3358@2|Bacteria,2G9CX@200795|Chloroflexi,27Z2J@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1684)	-	-	-	ko:K09164	-	-	-	-	ko00000	-	-	-	DUF1684
REGS1_k127_4967876_14	926569.ANT_08670	8.324e-45	169.0	COG1514@1|root,COG1514@2|Bacteria,2G76S@200795|Chloroflexi	200795|Chloroflexi	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
REGS1_k127_4967876_16	926569.ANT_08660	9.994e-34	132.0	COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi	200795|Chloroflexi	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
REGS1_k127_4967876_7	926569.ANT_18710	8.881e-70	239.0	COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi	200795|Chloroflexi	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
REGS1_k127_4967876_18	926569.ANT_18700	1.48e-13	79.0	COG0457@1|root,COG0457@2|Bacteria,2G70Z@200795|Chloroflexi	200795|Chloroflexi	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r1_1,TPR_16,TPR_19,TPR_8
REGS1_k127_4968441_2	448385.sce5828	5.039e-24	109.0	COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,42UR3@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	TIGRFAM geranylgeranyl reductase	-	-	1.3.1.111,1.3.1.83	ko:K10960	ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110	-	R02063,R08754,R08755,R08756,R11226,R11518	RC00212,RC00522,RC01823	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3,FAD_oxidored
REGS1_k127_4968441_1	666686.B1NLA3E_20030	5.042e-41	165.0	COG3274@1|root,COG3274@2|Bacteria,1V0QX@1239|Firmicutes,4HFH3@91061|Bacilli,1ZHG6@1386|Bacillus	91061|Bacilli	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
REGS1_k127_4968441_0	926569.ANT_08730	4.533e-90	298.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
REGS1_k127_4990832_4	926569.ANT_18580	8.228e-09	59.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
REGS1_k127_4990832_2	926569.ANT_18580	1.213e-36	147.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	SH3_3
REGS1_k127_4990832_3	309801.trd_1553	1.422e-14	78.0	COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi,27YEW@189775|Thermomicrobia	189775|Thermomicrobia	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
REGS1_k127_4990832_0	1195236.CTER_0541	3.454e-296	927.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3WHVU@541000|Ruminococcaceae	186801|Clostridia	C	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
REGS1_k127_4990832_1	658655.HMPREF0988_01739	1.661e-71	261.0	28MZN@1|root,2ZB6B@2|Bacteria,1TTSM@1239|Firmicutes,24A84@186801|Clostridia,27SEB@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5018236_0	1382359.JIAL01000001_gene1899	0.0	1083.0	COG1629@1|root,COG1629@2|Bacteria,3Y9BW@57723|Acidobacteria,2JP0H@204432|Acidobacteriia	204432|Acidobacteriia	P	PFAM TonB-dependent Receptor Plug	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Plug
REGS1_k127_5018236_1	572480.Arnit_0841	4.033e-07	59.0	COG1846@1|root,COG1846@2|Bacteria,1N75F@1224|Proteobacteria,42VDI@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	transcriptional regulator (MarR	-	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
REGS1_k127_5018615_2	926569.ANT_27610	1.879e-179	567.0	COG0554@1|root,COG0554@2|Bacteria,2G5TV@200795|Chloroflexi	200795|Chloroflexi	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
REGS1_k127_5018615_4	1312959.KI914645_gene983	1.853e-168	546.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,1W8QW@1268|Micrococcaceae	201174|Actinobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
REGS1_k127_5018615_8	926569.ANT_20140	1.54e-83	289.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	2|Bacteria	M	PFAM Glycosyl transferase family 2	wcqE	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
REGS1_k127_5018615_10	375451.RD1_0571	2.607e-56	205.0	COG0224@1|root,COG0224@2|Bacteria,1QUME@1224|Proteobacteria	1224|Proteobacteria	C	PFAM WbqC-like family protein	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
REGS1_k127_5018615_3	926569.ANT_20160	1.766e-178	566.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	wecE	GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	iE2348C_1286.E2348C_4092,iEC55989_1330.EC55989_4263,iECIAI1_1343.ECIAI1_3978,iECIAI39_1322.ECIAI39_2996,iECO103_1326.ECO103_4373,iECO111_1330.ECO111_4617,iECO26_1355.ECO26_4795,iECUMN_1333.ECUMN_4316,iECW_1372.ECW_m4089,iEKO11_1354.EKO11_4565,iSSON_1240.SSON_3963,iWFL_1372.ECW_m4089	DegT_DnrJ_EryC1
REGS1_k127_5018615_6	926569.ANT_29590	8.001e-111	367.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
REGS1_k127_5018615_7	926569.ANT_20830	1.762e-106	356.0	COG1893@1|root,COG1893@2|Bacteria,2G718@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
REGS1_k127_5018615_0	452637.Oter_2238	1.23e-213	677.0	COG0441@1|root,COG0572@1|root,COG0441@2|Bacteria,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
REGS1_k127_5018615_11	879212.DespoDRAFT_00594	3.146e-51	187.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2WNEN@28221|Deltaproteobacteria,2MK2I@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
REGS1_k127_5018615_9	706587.Desti_2991	2.165e-71	251.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_11,RrnaAD
REGS1_k127_5018615_5	269799.Gmet_2573	4.784e-147	476.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43T9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
REGS1_k127_5018615_1	1100721.ALKO01000020_gene911	3.088e-204	650.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4A9Z9@80864|Comamonadaceae	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_5020081_0	42256.RradSPS_0358	4.279e-159	543.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
REGS1_k127_5020081_1	1121035.AUCH01000004_gene310	1.393e-42	181.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate Guanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
REGS1_k127_5075642_3	926569.ANT_13350	7.663e-16	79.0	COG1171@1|root,COG1171@2|Bacteria,2G6ME@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_5075642_0	926569.ANT_13340	3.105e-256	818.0	COG1472@1|root,COG1472@2|Bacteria,2G7PD@200795|Chloroflexi	200795|Chloroflexi	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
REGS1_k127_5075642_1	926569.ANT_13330	2.885e-138	447.0	COG0515@1|root,COG0515@2|Bacteria,2G850@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_5075642_2	926569.ANT_13320	2.78e-23	100.0	COG0745@1|root,COG1716@1|root,COG0745@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Guanylate_cyc,RDD,Trans_reg_C,Yop-YscD_cpl
REGS1_k127_5090885_1	926569.ANT_08110	4.649e-117	383.0	COG1940@1|root,COG1940@2|Bacteria	2|Bacteria	GK	ROK family	-	-	2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9	ko:K00845,ko:K13967,ko:K19979,ko:K20433	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko00525,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map00525,map01100,map01110,map01120,map01130,map01200	M00001,M00549,M00814,M00815	R00299,R01600,R01786,R02087,R02705,R11185,R11234	RC00002,RC00017,RC00290	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
REGS1_k127_5090885_0	926569.ANT_08120	2.073e-143	467.0	COG1940@1|root,COG1940@2|Bacteria,2G7R1@200795|Chloroflexi	200795|Chloroflexi	K	PFAM ROK family protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
REGS1_k127_5090885_3	324602.Caur_0124	1.741e-68	243.0	COG4223@1|root,COG4223@2|Bacteria	2|Bacteria	DZ	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631
REGS1_k127_5090885_5	1370121.AUWS01000024_gene2537	3.15e-48	184.0	COG1349@1|root,COG1349@2|Bacteria,2H5X4@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, DeoR family	-	-	-	ko:K02081,ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
REGS1_k127_5090885_4	180332.JTGN01000001_gene4743	4.327e-64	229.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249S6@186801|Clostridia	1239|Firmicutes	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
REGS1_k127_5090885_2	180332.JTGN01000001_gene4744	8.584e-95	319.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
REGS1_k127_5194389_6	926569.ANT_27260	1.381e-47	186.0	COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
REGS1_k127_5194389_7	926569.ANT_15850	7.872e-37	158.0	COG4745@1|root,COG4745@2|Bacteria,2G9RB@200795|Chloroflexi	200795|Chloroflexi	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5194389_4	926569.ANT_10810	1.596e-78	269.0	COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
REGS1_k127_5194389_10	1303518.CCALI_02615	1.757e-26	118.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	cmk	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase,Cytidylate_kin
REGS1_k127_5194389_0	671143.DAMO_0407	5.94e-277	867.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_5194389_1	671143.DAMO_0407	3.622e-266	834.0	COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria	2|Bacteria	E	Amino acid permease	ydaO	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_5194389_5	671143.DAMO_1520	4.408e-70	244.0	COG0569@1|root,COG0569@2|Bacteria,2NPXT@2323|unclassified Bacteria	2|Bacteria	P	TrkA-N domain	ceoB	-	-	ko:K03499,ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6,2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
REGS1_k127_5194389_3	671143.DAMO_1521	7.591e-80	273.0	COG0569@1|root,COG0569@2|Bacteria,2NPN3@2323|unclassified Bacteria	2|Bacteria	P	TrkA-C domain	trkA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
REGS1_k127_5194389_13	926569.ANT_22940	1.062e-20	92.0	COG0230@1|root,COG0230@2|Bacteria	2|Bacteria	J	Ribosomal protein L34	rpmH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
REGS1_k127_5194389_11	926569.ANT_22930	3.238e-22	101.0	COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi	200795|Chloroflexi	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
REGS1_k127_5194389_8	926569.ANT_22920	2.576e-36	140.0	COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi	200795|Chloroflexi	S	Could be involved in insertion of integral membrane proteins into the membrane	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
REGS1_k127_5194389_12	1306990.BARG01000042_gene4905	3.136e-21	106.0	COG1520@1|root,COG4249@1|root,COG1520@2|Bacteria,COG4249@2|Bacteria,2IAM3@201174|Actinobacteria	201174|Actinobacteria	U	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
REGS1_k127_5194389_2	926569.ANT_22900	1.782e-81	280.0	COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi	200795|Chloroflexi	U	PFAM 60 kDa inner membrane insertion protein	-	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
REGS1_k127_5194389_9	926569.ANT_22890	3.046e-28	121.0	COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
REGS1_k127_52178_1	926569.ANT_17120	2.469e-82	276.0	COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi	200795|Chloroflexi	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441,ko:K10545,ko:K10548	ko02010,map02010	M00212,M00215,M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4,3.A.1.2.5	-	-	ABC_tran
REGS1_k127_52178_0	926569.ANT_17110	1.052e-165	530.0	COG4214@1|root,COG4214@2|Bacteria,2G8H9@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10544,ko:K10547	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	BPD_transp_2
REGS1_k127_5220199_5	926569.ANT_22190	1.37e-10	72.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
REGS1_k127_5220199_3	926569.ANT_22190	4.05e-22	104.0	COG1572@1|root,COG1572@2|Bacteria,2G9M8@200795|Chloroflexi	2|Bacteria	S	Ig-like domain from next to BRCA1 gene	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,N_BRCA1_IG
REGS1_k127_5220199_0	926569.ANT_23050	3.791e-109	364.0	COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Dehalogenase,Fer4_16,HEAT_2
REGS1_k127_5220199_1	926569.ANT_04120	1.472e-72	252.0	COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi	200795|Chloroflexi	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
REGS1_k127_5220199_2	926550.CLDAP_16010	4.011e-56	205.0	COG2267@1|root,COG2267@2|Bacteria,2G6W2@200795|Chloroflexi	200795|Chloroflexi	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
REGS1_k127_5220199_4	65393.PCC7424_5869	5.931e-13	76.0	2CGDF@1|root,34388@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_522280_3	926569.ANT_15070	5.026e-61	227.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	-
REGS1_k127_522280_4	545693.BMQ_2855	1.183e-60	218.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,1ZDR0@1386|Bacillus	91061|Bacilli	K	Transcriptional regulator	kipR	-	-	ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
REGS1_k127_522280_0	1380355.JNIJ01000042_gene5157	3.596e-158	513.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria,3JTBD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_522280_1	1380355.JNIJ01000042_gene5158	8.584e-158	512.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,3JQYV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10441,ko:K10562	ko02010,map02010	M00212,M00220	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	ABC_tran
REGS1_k127_522280_2	1380355.JNIJ01000042_gene5159	3.687e-102	343.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2U0D6@28211|Alphaproteobacteria,3JW92@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Branched-chain amino acid transport system / permease component	MA20_14315	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
REGS1_k127_5242968_2	926569.ANT_01830	3.678e-47	171.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
REGS1_k127_5242968_1	926569.ANT_01830	0.0	1060.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
REGS1_k127_5242968_0	926569.ANT_25290	0.0	1394.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
REGS1_k127_5259245_5	309801.trd_0489	2.158e-51	191.0	COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi,27XM3@189775|Thermomicrobia	189775|Thermomicrobia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
REGS1_k127_5259245_2	926569.ANT_18190	9.747e-106	352.0	COG1774@1|root,COG1774@2|Bacteria,2G6AJ@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
REGS1_k127_5259245_1	926569.ANT_18200	3.22e-159	508.0	COG0489@1|root,COG0489@2|Bacteria,2G60P@200795|Chloroflexi	200795|Chloroflexi	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
REGS1_k127_5259245_4	926569.ANT_18220	9.66e-83	279.0	COG1143@1|root,COG1143@2|Bacteria,2G6SE@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.6.5.3	ko:K00338,ko:K03615	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
REGS1_k127_5259245_0	926569.ANT_18230	4.145e-259	818.0	COG0649@1|root,COG0852@1|root,COG0649@2|Bacteria,COG0852@2|Bacteria,2G5JF@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
REGS1_k127_5259245_3	926569.ANT_18240	1.289e-100	333.0	COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
REGS1_k127_5259245_6	123899.JPQP01000001_gene1660	1.764e-08	59.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,3T86B@506|Alcaligenaceae	28216|Betaproteobacteria	S	Iron-sulphur cluster assembly	iscX	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
REGS1_k127_5302907_11	329726.AM1_G0164	1.513e-09	59.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	NB-ARC,WD40
REGS1_k127_5302907_12	1410653.JHVC01000013_gene3610	0.0001428	52.0	2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,36IC8@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5302907_6	926569.ANT_30350	6.214e-66	246.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5302907_10	1218084.BBJK01000145_gene7434	1.294e-19	91.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,2VVQ9@28216|Betaproteobacteria,1K9G8@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
REGS1_k127_5302907_4	926569.ANT_30070	2.872e-91	307.0	COG0357@1|root,COG0357@2|Bacteria,2G6HF@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
REGS1_k127_5302907_7	926569.ANT_11900	9.398e-51	193.0	COG5662@1|root,COG5662@2|Bacteria,2GBKH@200795|Chloroflexi	200795|Chloroflexi	K	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
REGS1_k127_5302907_5	926569.ANT_11910	1.715e-81	278.0	COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi	200795|Chloroflexi	T	PFAM metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
REGS1_k127_5302907_1	504728.K649_12305	4.947e-146	472.0	COG0452@1|root,COG0452@2|Bacteria,1WIH0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
REGS1_k127_5302907_8	321327.CYA_2243	1.898e-50	190.0	COG1881@1|root,COG1881@2|Bacteria,1G5SZ@1117|Cyanobacteria,1H1NJ@1129|Synechococcus	1117|Cyanobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
REGS1_k127_5302907_9	886293.Sinac_6048	3.005e-41	158.0	COG0454@1|root,COG0454@2|Bacteria,2J01A@203682|Planctomycetes	203682|Planctomycetes	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K18816	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	Acetyltransf_1
REGS1_k127_5302907_0	926569.ANT_10870	1.421e-280	886.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
REGS1_k127_5302907_2	926569.ANT_08960	6.494e-113	376.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,2G8NY@200795|Chloroflexi	200795|Chloroflexi	K	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
REGS1_k127_5302907_3	1293054.HSACCH_00979	4.203e-107	363.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,249WU@186801|Clostridia,3WB1M@53433|Halanaerobiales	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
REGS1_k127_5326138_0	1267535.KB906767_gene5363	9.699e-73	251.0	COG3547@1|root,COG3547@2|Bacteria,3Y6PK@57723|Acidobacteria	57723|Acidobacteria	L	PFAM transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_5326138_1	903818.KI912268_gene2586	2.472e-25	109.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg
REGS1_k127_5333925_11	926569.ANT_15270	1.97e-45	166.0	COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi	200795|Chloroflexi	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
REGS1_k127_5333925_5	926569.ANT_15280	1.032e-70	243.0	COG0669@1|root,COG0669@2|Bacteria,2G6NZ@200795|Chloroflexi	200795|Chloroflexi	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_5333925_10	926569.ANT_15290	4.923e-51	186.0	COG0711@1|root,COG0711@2|Bacteria,2G79J@200795|Chloroflexi	200795|Chloroflexi	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5333925_3	926550.CLDAP_35910	1.402e-88	299.0	COG2521@1|root,COG2521@2|Bacteria,2G7RX@200795|Chloroflexi	200795|Chloroflexi	S	Methyltransferase domain	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_11
REGS1_k127_5333925_0	269799.Gmet_3493	0.0	1053.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome c oxidase, subunit I	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
REGS1_k127_5333925_1	909663.KI867150_gene2869	1.577e-156	501.0	COG0006@1|root,COG0006@2|Bacteria,1QNPN@1224|Proteobacteria,431BA@68525|delta/epsilon subdivisions,2WW9X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
REGS1_k127_5333925_4	65393.PCC7424_0063	1.144e-87	298.0	COG3386@1|root,COG3386@2|Bacteria,1G2S8@1117|Cyanobacteria,3KJY9@43988|Cyanothece	1117|Cyanobacteria	G	PFAM SMP-30 Gluconolaconase LRE domain protein	-	-	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
REGS1_k127_5333925_2	1265505.ATUG01000003_gene681	8.112e-99	338.0	COG1228@1|root,COG1228@2|Bacteria,1MVAF@1224|Proteobacteria,42MKS@68525|delta/epsilon subdivisions,2WKIH@28221|Deltaproteobacteria,2MI42@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	PFAM amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
REGS1_k127_5333925_6	1123401.JHYQ01000002_gene2696	3.946e-69	248.0	COG0223@1|root,COG0223@2|Bacteria,1NN5V@1224|Proteobacteria,1SAZA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5333925_7	383372.Rcas_2439	4.617e-60	218.0	COG3375@1|root,COG3375@2|Bacteria,2G8MH@200795|Chloroflexi,37765@32061|Chloroflexia	32061|Chloroflexia	M	carboxylic acid catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5333925_8	926569.ANT_17350	2.525e-58	215.0	COG0702@1|root,COG0702@2|Bacteria,2G6I7@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
REGS1_k127_5368204_2	926569.ANT_10910	1.831e-41	165.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_5368204_0	1131269.AQVV01000004_gene636	1.398e-49	191.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	phnD	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_5368204_1	1307761.L21SP2_1483	2.097e-45	168.0	COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes	203691|Spirochaetes	P	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system	phnC	-	3.6.3.28	ko:K02041	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.9	-	-	ABC_tran
REGS1_k127_5372259_2	350058.Mvan_1114	1.836e-36	155.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria,236NP@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
REGS1_k127_5372259_0	350054.Mflv_4645	2.665e-45	178.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria,2374G@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_5372259_1	518766.Rmar_0977	2.05e-39	161.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1FJ4P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
REGS1_k127_5372259_4	509191.AEDB02000080_gene5152	8.955e-06	55.0	COG3464@1|root,COG3464@2|Bacteria,1VFE7@1239|Firmicutes,24U01@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5372259_3	1254432.SCE1572_31350	2.101e-08	59.0	COG1695@1|root,COG1695@2|Bacteria	2|Bacteria	K	negative regulation of transcription, DNA-templated	-	-	-	-	-	-	-	-	-	-	-	-	DUF4180,PadR
REGS1_k127_5376487_3	1124780.ANNU01000036_gene2	8.598e-36	149.0	299R9@1|root,2ZWTI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5376487_0	880073.Calab_0341	9.596e-246	775.0	COG2986@1|root,COG2986@2|Bacteria,2NQHF@2323|unclassified Bacteria	2|Bacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
REGS1_k127_5376487_1	383372.Rcas_2918	1.487e-71	253.0	COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,374Z1@32061|Chloroflexia	32061|Chloroflexia	BQ	PFAM histone deacetylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
REGS1_k127_5376487_4	926569.ANT_01320	7.849e-30	124.0	COG3688@1|root,COG3688@2|Bacteria,2G95S@200795|Chloroflexi	200795|Chloroflexi	S	YacP-like NYN domain	-	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	NYN_YacP
REGS1_k127_5376487_2	926569.ANT_28850	4.415e-49	182.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	ycaO	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
REGS1_k127_5403984_0	521011.Mpal_1491	8.577e-22	100.0	arCOG01662@1|root,arCOG01662@2157|Archaea,2XX49@28890|Euryarchaeota,2N9SA@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
REGS1_k127_5403984_1	1179773.BN6_79940	7.607e-12	76.0	COG1073@1|root,COG1073@2|Bacteria,2IDQ6@201174|Actinobacteria,4DZ15@85010|Pseudonocardiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH,Hydrolase_4
REGS1_k127_5403984_2	863239.AFIZ01000024_gene2554	0.0003341	44.0	COG2202@1|root,COG2202@2|Bacteria,2I5CA@201174|Actinobacteria,22NIH@1653|Corynebacteriaceae	201174|Actinobacteria	T	FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
REGS1_k127_5417342_1	926569.ANT_18990	2.559e-97	319.0	COG0250@1|root,COG0250@2|Bacteria,2G6A3@200795|Chloroflexi	200795|Chloroflexi	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
REGS1_k127_5417342_3	926569.ANT_18980	1.398e-69	239.0	COG0080@1|root,COG0080@2|Bacteria,2G6FF@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
REGS1_k127_5417342_0	926569.ANT_18970	4.887e-104	344.0	COG0081@1|root,COG0081@2|Bacteria,2G6AW@200795|Chloroflexi	200795|Chloroflexi	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
REGS1_k127_5417342_4	926569.ANT_18960	1.09e-48	179.0	COG0244@1|root,COG0244@2|Bacteria,2G6XJ@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
REGS1_k127_5417342_5	926569.ANT_18950	1.052e-45	169.0	COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi	200795|Chloroflexi	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
REGS1_k127_5417342_6	1385520.N802_17975	7.411e-08	64.0	COG2186@1|root,COG2186@2|Bacteria,2HQFA@201174|Actinobacteria,4FE6B@85021|Intrasporangiaceae	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
REGS1_k127_5417342_2	886293.Sinac_1731	3.479e-71	252.0	COG0476@1|root,COG0476@2|Bacteria,2IY9K@203682|Planctomycetes	203682|Planctomycetes	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
REGS1_k127_5438895_6	926550.CLDAP_35820	4.736e-22	103.0	COG3255@1|root,COG3255@2|Bacteria,2G95B@200795|Chloroflexi	200795|Chloroflexi	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
REGS1_k127_5438895_0	926550.CLDAP_18740	2.637e-104	349.0	COG0834@1|root,COG0834@2|Bacteria	2|Bacteria	ET	amino acid transport	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
REGS1_k127_5438895_1	926550.CLDAP_18750	6.141e-95	319.0	COG0765@1|root,COG0765@2|Bacteria,2G6IJ@200795|Chloroflexi	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
REGS1_k127_5438895_2	1121422.AUMW01000005_gene665	4.272e-87	295.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,261BM@186807|Peptococcaceae	186801|Clostridia	E	ABC transporter	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
REGS1_k127_5438895_4	1382306.JNIM01000001_gene4136	2.65e-48	186.0	COG0834@1|root,COG0834@2|Bacteria,2G7BD@200795|Chloroflexi	200795|Chloroflexi	ET	COGs COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
REGS1_k127_5438895_3	1449346.JQMO01000002_gene397	2.725e-71	250.0	COG0765@1|root,COG0765@2|Bacteria,2GJJ9@201174|Actinobacteria,2M0ZK@2063|Kitasatospora	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
REGS1_k127_5438895_5	1380391.JIAS01000012_gene3972	1.221e-45	168.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,2TQX2@28211|Alphaproteobacteria,2JV02@204441|Rhodospirillales	204441|Rhodospirillales	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
REGS1_k127_5465293_2	330214.NIDE4075	3.263e-24	104.0	COG1826@1|root,COG1826@2|Bacteria,3J1A4@40117|Nitrospirae	40117|Nitrospirae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_5465293_1	330214.NIDE4074	3.752e-38	144.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_5465293_0	330214.NIDE4073	4.307e-241	758.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	VPA1441	-	-	-	-	-	-	-	-	-	-	-	Alginate_exp,FG-GAP_2,OprD,Porin_4
REGS1_k127_5500220_4	1205680.CAKO01000006_gene3394	0.000703	51.0	2BJ7Y@1|root,32DHE@2|Bacteria,1NTKD@1224|Proteobacteria,2UPK5@28211|Alphaproteobacteria	1205680.CAKO01000006_gene3394|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5500220_1	870187.Thini_3469	3.115e-83	289.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
REGS1_k127_5500220_2	1205680.CAKO01000038_gene1840	5.323e-35	138.0	2E3ZS@1|root,32YWP@2|Bacteria,1NAZV@1224|Proteobacteria,2UGW3@28211|Alphaproteobacteria,2JXCF@204441|Rhodospirillales	204441|Rhodospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5500220_3	1123355.JHYO01000003_gene2881	5.627e-14	72.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,2UJXH@28211|Alphaproteobacteria,37108@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5500220_0	1244869.H261_07753	7.337e-302	936.0	COG2192@1|root,COG2192@2|Bacteria,1MWBA@1224|Proteobacteria,2TV6G@28211|Alphaproteobacteria,2JRX0@204441|Rhodospirillales	204441|Rhodospirillales	O	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
REGS1_k127_5519895_3	1306990.BARG01000031_gene3411	5.212e-43	169.0	COG0815@1|root,COG0815@2|Bacteria,2GP8X@201174|Actinobacteria	201174|Actinobacteria	M	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
REGS1_k127_5519895_0	926569.ANT_05360	1.655e-234	743.0	COG1243@1|root,COG1243@2|Bacteria,2G5ZZ@200795|Chloroflexi	200795|Chloroflexi	BK	Radical_SAM C-terminal domain	-	-	2.3.1.48	ko:K07739	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	Acetyltransf_1,Radical_SAM,Radical_SAM_C
REGS1_k127_5519895_2	926569.ANT_05350	7.298e-50	186.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
REGS1_k127_5519895_1	215803.DB30_0760	9.244e-57	203.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,42PPN@68525|delta/epsilon subdivisions,2WK8S@28221|Deltaproteobacteria,2Z1ED@29|Myxococcales	28221|Deltaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
REGS1_k127_5529927_4	479434.Sthe_2019	2.478e-09	65.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi,27Y6A@189775|Thermomicrobia	189775|Thermomicrobia	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_5529927_1	926569.ANT_11940	3.431e-116	379.0	COG1521@1|root,COG1521@2|Bacteria,2G6B4@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
REGS1_k127_5529927_3	344747.PM8797T_15953	1.365e-14	87.0	2A5HC@1|root,30U7J@2|Bacteria,2J2HM@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5529927_0	926569.ANT_11950	3.952e-264	826.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,2G674@200795|Chloroflexi	200795|Chloroflexi	H	Homocysteine S-methyltransferase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR,S-methyl_trans
REGS1_k127_5529927_2	1128427.KB904821_gene157	2.959e-23	106.0	COG1807@1|root,COG1807@2|Bacteria,1GCBE@1117|Cyanobacteria,1HE3B@1150|Oscillatoriales	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5536950_2	926569.ANT_05390	0.0005016	42.0	COG1240@1|root,COG1240@2|Bacteria,2G7UF@200795|Chloroflexi	200795|Chloroflexi	H	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2
REGS1_k127_5536950_1	521098.Aaci_2319	1.187e-23	115.0	COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9UE@91061|Bacilli,278Q8@186823|Alicyclobacillaceae	91061|Bacilli	EGP	MFS/sugar transport protein	-	-	-	ko:K08161	-	-	-	-	ko00000,ko02000	2.A.1.2.20	-	-	MFS_1,MFS_1_like,Sugar_tr
REGS1_k127_5536950_0	926569.ANT_19600	6.32e-114	373.0	COG2189@1|root,COG2189@2|Bacteria,2G7K2@200795|Chloroflexi	200795|Chloroflexi	L	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
REGS1_k127_5548595_1	234267.Acid_6086	5.417e-56	197.0	COG0457@1|root,COG0457@2|Bacteria	234267.Acid_6086|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5548595_2	1033734.CAET01000065_gene2187	2.905e-40	154.0	2DB7A@1|root,2Z7KK@2|Bacteria,1TQ2C@1239|Firmicutes,4HFKE@91061|Bacilli,1ZBHA@1386|Bacillus	91061|Bacilli	S	Glycosyl hydrolase family 115	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_115
REGS1_k127_5548595_3	1122222.AXWR01000010_gene77	3.848e-05	52.0	COG2115@1|root,COG2115@2|Bacteria,1WJGE@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
REGS1_k127_5548595_0	204669.Acid345_0904	3.914e-103	339.0	COG1070@1|root,COG1070@2|Bacteria,3Y2V6@57723|Acidobacteria,2JJ35@204432|Acidobacteriia	204432|Acidobacteriia	G	FGGY family of carbohydrate kinases, N-terminal domain	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
REGS1_k127_5552505_1	1216932.CM240_3316	3.977e-09	66.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,36FZK@31979|Clostridiaceae	186801|Clostridia	M	family 25	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
REGS1_k127_5552505_0	926569.ANT_23100	0.0	1373.0	COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
REGS1_k127_5559820_5	882086.SacxiDRAFT_3512	2.966e-11	64.0	COG1977@1|root,COG1977@2|Bacteria,2IQJJ@201174|Actinobacteria,4E613@85010|Pseudonocardiales	201174|Actinobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	ThiS
REGS1_k127_5559820_3	331113.SNE_A20910	1.37e-30	128.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
REGS1_k127_5559820_2	1267535.KB906767_gene3397	3.157e-43	159.0	COG1977@1|root,COG1977@2|Bacteria,3Y5J3@57723|Acidobacteria,2JJVU@204432|Acidobacteriia	204432|Acidobacteriia	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5559820_1	1504981.KO116_2129	2.187e-47	178.0	2ABSC@1|root,3118T@2|Bacteria,1RDBX@1224|Proteobacteria,1S5RV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5559820_4	1278307.KB906976_gene1627	1.387e-14	82.0	2EJVS@1|root,33DKH@2|Bacteria,1NJHZ@1224|Proteobacteria,1T694@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5559820_0	639030.JHVA01000001_gene1853	1.33e-108	352.0	COG4447@1|root,COG4447@2|Bacteria,3Y3TM@57723|Acidobacteria,2JHSZ@204432|Acidobacteriia	204432|Acidobacteriia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
REGS1_k127_5563724_0	926550.CLDAP_29790	2.324e-100	339.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_5563724_1	1128421.JAGA01000002_gene1294	3.726e-30	127.0	COG0683@1|root,COG0683@2|Bacteria,2NPSN@2323|unclassified Bacteria	2|Bacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_5608164_3	1380355.JNIJ01000041_gene5260	6.711e-26	107.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
REGS1_k127_5608164_4	1353528.DT23_18755	7.431e-10	61.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria,2XKI8@285107|Thioclava	28211|Alphaproteobacteria	L	Homeodomain-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
REGS1_k127_5608164_2	485913.Krac_6524	3.967e-32	129.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
REGS1_k127_5608164_1	1297742.A176_04294	4.987e-44	169.0	COG4977@1|root,COG4977@2|Bacteria,1MUDK@1224|Proteobacteria,42QRG@68525|delta/epsilon subdivisions,2WJ5Z@28221|Deltaproteobacteria,2YZ40@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
REGS1_k127_5608164_0	485913.Krac_5076	9.781e-104	346.0	COG0243@1|root,COG0243@2|Bacteria,2G5X7@200795|Chloroflexi	485913.Krac_5076|-	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5620454_0	1267535.KB906767_gene4070	4.94e-74	261.0	COG3570@1|root,COG3570@2|Bacteria	2|Bacteria	V	aminoglycoside hydroxyurea antibiotic resistance kinase	strB	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
REGS1_k127_5620454_3	1382306.JNIM01000001_gene3668	2.18e-16	90.0	COG0454@1|root,COG0456@2|Bacteria,2G9G9@200795|Chloroflexi	200795|Chloroflexi	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_5620454_2	1118054.CAGW01000032_gene684	6.047e-36	154.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,4HC54@91061|Bacilli,2758S@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
REGS1_k127_5620454_1	373903.Hore_13850	7.492e-58	207.0	COG1573@1|root,COG1573@2|Bacteria,1V1SU@1239|Firmicutes,24E7B@186801|Clostridia	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
REGS1_k127_56576_0	926569.ANT_25010	1.737e-189	594.0	COG1509@1|root,COG1509@2|Bacteria,2G7ZT@200795|Chloroflexi	200795|Chloroflexi	H	Lysine-2,3-aminomutase	-	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,LAM_C,Radical_SAM
REGS1_k127_5734813_9	485913.Krac_9872	2.57e-06	50.0	COG5485@1|root,COG5485@2|Bacteria,2G7DA@200795|Chloroflexi	200795|Chloroflexi	P	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
REGS1_k127_5734813_1	926550.CLDAP_40620	2.437e-129	421.0	COG0169@1|root,COG0169@2|Bacteria,2G8BG@200795|Chloroflexi	200795|Chloroflexi	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5734813_6	926550.CLDAP_40630	9.399e-81	276.0	COG0800@1|root,COG0800@2|Bacteria,2G8MI@200795|Chloroflexi	200795|Chloroflexi	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
REGS1_k127_5734813_2	926550.CLDAP_40640	6.192e-129	424.0	COG0111@1|root,COG0111@2|Bacteria,2G7NG@200795|Chloroflexi	200795|Chloroflexi	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
REGS1_k127_5734813_8	926550.CLDAP_40650	3.614e-61	217.0	COG2140@1|root,COG2140@2|Bacteria,2G9AT@200795|Chloroflexi	200795|Chloroflexi	G	Glucose-6-phosphate isomerase (GPI)	-	-	5.3.1.9	ko:K06859	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	GPI
REGS1_k127_5734813_7	1382306.JNIM01000001_gene2964	3.008e-61	223.0	COG1735@1|root,COG1735@2|Bacteria	2|Bacteria	S	zinc ion binding	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
REGS1_k127_5734813_3	1304865.JAGF01000001_gene2276	1.084e-96	327.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	tdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_5734813_4	1304865.JAGF01000001_gene2275	3.8e-96	325.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4F2YX@85016|Cellulomonadaceae	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_5734813_0	926550.CLDAP_32900	8.794e-167	539.0	COG1070@1|root,COG1070@2|Bacteria	2|Bacteria	G	xylulokinase activity	-	-	2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5	ko:K00848,ko:K00851,ko:K00854,ko:K00862	ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200	M00014	R01639,R01737,R01902,R03014,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
REGS1_k127_5734813_5	926550.CLDAP_32840	7.947e-92	310.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_5742196_12	404589.Anae109_2774	4.959e-13	69.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_5742196_2	1123073.KB899242_gene1152	1.256e-144	469.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,1RMMJ@1236|Gammaproteobacteria,1X2XI@135614|Xanthomonadales	135614|Xanthomonadales	I	acyl-CoA dehydrogenase	acdA	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_5742196_7	525904.Tter_0351	4.289e-58	213.0	COG2362@1|root,COG2362@2|Bacteria,2NPDW@2323|unclassified Bacteria	2|Bacteria	E	D-aminopeptidase	-	-	-	ko:K16203	-	-	-	-	ko00000,ko01000,ko01002	3.A.1.5.2	-	-	Peptidase_M55
REGS1_k127_5742196_0	321332.CYB_1464	9.346e-172	548.0	COG0687@1|root,COG0687@2|Bacteria,1G0DM@1117|Cyanobacteria	1117|Cyanobacteria	E	Extracellular solute-binding protein	-	-	-	ko:K02055,ko:K11069	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	SBP_bac_8
REGS1_k127_5742196_3	926550.CLDAP_19330	1.613e-136	443.0	COG3842@1|root,COG3842@2|Bacteria	2|Bacteria	P	ATPase activity	ydcT	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
REGS1_k127_5742196_4	395961.Cyan7425_3620	3.17e-115	378.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria,3KIME@43988|Cyanothece	1117|Cyanobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
REGS1_k127_5742196_5	926550.CLDAP_19350	4.752e-103	342.0	COG1177@1|root,COG1177@2|Bacteria	2|Bacteria	P	DNA import into cell involved in transformation	ydcV	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657	-	ko:K02053,ko:K11070	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	iEC55989_1330.EC55989_1575,iECIAI1_1343.ECIAI1_1439,iECO111_1330.ECO111_1832,iECO26_1355.ECO26_2042,iECW_1372.ECW_m1571,iECs_1301.ECs2047,iEKO11_1354.EKO11_2376,iUMNK88_1353.UMNK88_1846,iWFL_1372.ECW_m1571,iZ_1308.Z2276,ic_1306.c1867	BPD_transp_1
REGS1_k127_5742196_8	926569.ANT_22220	9.009e-54	196.0	COG2940@1|root,COG2940@2|Bacteria,2G9DE@200795|Chloroflexi	200795|Chloroflexi	S	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain	-	-	-	-	-	-	-	-	-	-	-	-	SET
REGS1_k127_5742196_11	667014.Thein_1743	5.927e-14	85.0	COG1807@1|root,COG1807@2|Bacteria,2GIEC@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5742196_6	357808.RoseRS_3747	2.328e-72	249.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
REGS1_k127_5742196_10	1082933.MEA186_23816	8.517e-17	87.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.1.1.137,2.3.1.1	ko:K00537,ko:K00619,ko:K07755	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,C_GCAxxG_C_C
REGS1_k127_5742196_9	1121952.ATXT01000011_gene3001	1.287e-36	145.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4FPAM@85023|Microbacteriaceae	201174|Actinobacteria	L	SLBB domain	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
REGS1_k127_5742196_1	926550.CLDAP_27570	6.621e-164	524.0	COG1960@1|root,COG1960@2|Bacteria,2G5K3@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_5769892_2	318161.Sden_2935	6.143e-39	154.0	COG2020@1|root,COG2020@2|Bacteria,1MZ7S@1224|Proteobacteria,1S8Y4@1236|Gammaproteobacteria,2QCNX@267890|Shewanellaceae	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_5769892_3	1192124.LIG30_4445	2.829e-06	53.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,2VXXB@28216|Betaproteobacteria,1K9C3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
REGS1_k127_5769892_0	330214.NIDE1132	3.981e-293	914.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
REGS1_k127_5769892_1	1337936.IJ00_01175	1.43e-48	174.0	COG1452@1|root,COG1452@2|Bacteria,1G0TW@1117|Cyanobacteria,1HKTW@1161|Nostocales	1117|Cyanobacteria	M	PFAM Mannosyl oligosaccharide glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
REGS1_k127_5782341_13	926569.ANT_25980	9.962e-51	187.0	COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi	200795|Chloroflexi	O	NfeD-like C-terminal, partner-binding	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
REGS1_k127_5782341_10	525898.Sdel_1856	6.468e-78	273.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2YMQ7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
REGS1_k127_5782341_2	1499967.BAYZ01000028_gene1313	5.01e-103	344.0	COG0581@1|root,COG0581@2|Bacteria,2NPJS@2323|unclassified Bacteria	2|Bacteria	P	phosphate transport system permease protein	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
REGS1_k127_5782341_7	1499967.BAYZ01000028_gene1314	2.436e-88	304.0	COG0573@1|root,COG0573@2|Bacteria,2NPS2@2323|unclassified Bacteria	2|Bacteria	P	probably responsible for the translocation of the substrate across the membrane	-	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
REGS1_k127_5782341_5	593750.Metfor_0423	3.841e-90	307.0	COG0226@1|root,arCOG00213@2157|Archaea,2XW2U@28890|Euryarchaeota	28890|Euryarchaeota	P	ABC-type phosphate transport system, periplasmic component	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_5782341_15	316067.Geob_1650	3.407e-44	165.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,43ABU@68525|delta/epsilon subdivisions,2WVAV@28221|Deltaproteobacteria,43UYX@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
REGS1_k127_5782341_14	926550.CLDAP_06330	5.128e-46	170.0	COG2606@1|root,COG2606@2|Bacteria,2G931@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
REGS1_k127_5782341_6	926569.ANT_00170	1.513e-89	299.0	COG0177@1|root,COG0177@2|Bacteria,2G6QA@200795|Chloroflexi	200795|Chloroflexi	L	FES	-	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
REGS1_k127_5782341_3	926569.ANT_03120	4.771e-97	328.0	COG4448@1|root,COG4448@2|Bacteria	2|Bacteria	E	L-asparaginase II	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase_II
REGS1_k127_5782341_4	926569.ANT_03110	5.655e-91	308.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_5782341_0	926569.ANT_06880	2.239e-131	436.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
REGS1_k127_5782341_1	1144275.COCOR_02328	3.037e-129	427.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WPYW@28221|Deltaproteobacteria,2Z30A@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_5782341_12	926569.ANT_19610	2.242e-59	218.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_5782341_11	926569.ANT_13490	1.359e-69	255.0	COG0477@1|root,COG2814@2|Bacteria,2G6DM@200795|Chloroflexi	200795|Chloroflexi	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
REGS1_k127_5782341_8	629773.AORY01000014_gene2476	3.382e-84	288.0	COG1024@1|root,COG1024@2|Bacteria,1MWZC@1224|Proteobacteria,2TRYS@28211|Alphaproteobacteria,2K12I@204457|Sphingomonadales	204457|Sphingomonadales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
REGS1_k127_5782341_16	345341.KUTG_08687	5.916e-24	110.0	COG2020@1|root,COG2020@2|Bacteria,2HPCN@201174|Actinobacteria,4E7YM@85010|Pseudonocardiales	201174|Actinobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
REGS1_k127_5782341_9	926569.ANT_29760	3.651e-81	282.0	COG2746@1|root,COG2746@2|Bacteria	2|Bacteria	V	aminoglycoside 3-N-acetyltransferase activity	yokD	-	2.3.1.81	ko:K00662	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Antibiotic_NAT
REGS1_k127_5807208_1	1340493.JNIF01000003_gene3558	1.149e-140	449.0	COG1164@1|root,COG1164@2|Bacteria,3Y2SB@57723|Acidobacteria	57723|Acidobacteria	E	Angiotensin-converting enzyme	-	-	3.4.15.1	ko:K01283	ko04614,ko04924,ko05142,ko05410,map04614,map04924,map05142,map05410	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M2
REGS1_k127_5807208_0	1267535.KB906767_gene640	9.525e-163	520.0	COG0004@1|root,COG0004@2|Bacteria,3Y2VR@57723|Acidobacteria,2JHMR@204432|Acidobacteriia	204432|Acidobacteriia	P	Ammonium Transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
REGS1_k127_5827866_0	926569.ANT_24980	2.388e-182	583.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2G5QR@200795|Chloroflexi	200795|Chloroflexi	J	phenylalanyl-tRNA synthetase beta subunit	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
REGS1_k127_5827866_1	1382306.JNIM01000001_gene3886	5.616e-103	347.0	COG0016@1|root,COG0016@2|Bacteria,2G5T1@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
REGS1_k127_5827866_2	926550.CLDAP_32470	2.237e-49	198.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_5827866_4	1116232.AHBF01000137_gene1924	3.721e-15	83.0	2AYAN@1|root,31QD6@2|Bacteria,2H0HE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5827866_3	926569.ANT_04240	3.245e-35	143.0	COG0726@1|root,COG0726@2|Bacteria,2G6VJ@200795|Chloroflexi	200795|Chloroflexi	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_5835284_9	926569.ANT_06350	1.123e-70	247.0	COG1091@1|root,COG1091@2|Bacteria,2G9A2@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
REGS1_k127_5835284_14	344747.PM8797T_23856	1.448e-41	173.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_5835284_2	926569.ANT_06360	5.801e-156	499.0	COG2089@1|root,COG2089@2|Bacteria,2G8PB@200795|Chloroflexi	200795|Chloroflexi	M	SAF	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	NeuB,SAF
REGS1_k127_5835284_4	926569.ANT_06370	1.472e-118	392.0	COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_5835284_8	926569.ANT_06380	1.52e-75	263.0	COG1861@1|root,COG1861@2|Bacteria,2G8I7@200795|Chloroflexi	200795|Chloroflexi	M	Cytidylyltransferase	-	-	-	ko:K07257	-	-	-	-	ko00000	-	-	-	CTP_transf_3
REGS1_k127_5835284_7	926569.ANT_06390	8.937e-96	322.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
REGS1_k127_5835284_3	926569.ANT_06400	3.557e-133	430.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
REGS1_k127_5835284_1	926569.ANT_06410	1.539e-177	569.0	COG1887@1|root,COG1887@2|Bacteria	2|Bacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
REGS1_k127_5835284_16	1192868.CAIU01000013_gene1616	2.82e-22	98.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,2UKPX@28211|Alphaproteobacteria,43QUB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
REGS1_k127_5835284_15	398512.JQKC01000037_gene4525	9.497e-38	147.0	arCOG06631@1|root,32RY6@2|Bacteria,1V8RP@1239|Firmicutes,24MV5@186801|Clostridia,3WQ51@541000|Ruminococcaceae	186801|Clostridia	S	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_5835284_12	266117.Rxyl_3108	5.629e-49	188.0	COG4714@1|root,COG4714@2|Bacteria	2|Bacteria	EGP	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
REGS1_k127_5835284_11	926569.ANT_14460	1.143e-51	192.0	COG1319@1|root,COG1319@2|Bacteria,2G9PS@200795|Chloroflexi	200795|Chloroflexi	C	FAD binding domain in molybdopterin dehydrogenase	-	-	1.2.5.3	ko:K03519,ko:K12529	ko00450,map00450	-	R07229,R11168	RC02420,RC02800	ko00000,ko00001,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
REGS1_k127_5835284_10	926569.ANT_25970	8.683e-61	219.0	COG2050@1|root,COG2050@2|Bacteria,2G751@200795|Chloroflexi	200795|Chloroflexi	Q	Thioesterase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_5835284_6	383372.Rcas_3272	3.162e-102	347.0	COG2379@1|root,COG2379@2|Bacteria,2G5RZ@200795|Chloroflexi,374XG@32061|Chloroflexia	32061|Chloroflexia	C	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
REGS1_k127_5835284_5	1128421.JAGA01000002_gene1219	1.734e-118	389.0	COG1052@1|root,COG1052@2|Bacteria,2NNZP@2323|unclassified Bacteria	2|Bacteria	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	gyaR	-	1.1.1.26	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	-	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
REGS1_k127_5835284_0	926550.CLDAP_09870	4.833e-178	575.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	ycjM	-	2.4.1.7	ko:K00690	ko00500,map00500	-	R00803	RC00028	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
REGS1_k127_5835284_13	639282.DEFDS_1138	3.112e-46	171.0	COG0438@1|root,COG0438@2|Bacteria,2GGAH@200930|Deferribacteres	200930|Deferribacteres	H	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
REGS1_k127_5843964_3	926569.ANT_29800	2.972e-19	89.0	COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_5843964_0	357808.RoseRS_0235	0.0	1146.0	COG1048@1|root,COG1048@2|Bacteria,2G5NG@200795|Chloroflexi,374T1@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
REGS1_k127_5843964_1	926569.ANT_05570	2.523e-130	424.0	COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi	200795|Chloroflexi	F	PFAM Adenosine AMP deaminase	-	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
REGS1_k127_5843964_2	926569.ANT_25290	5.653e-34	137.0	COG0653@1|root,COG0653@2|Bacteria,2G603@200795|Chloroflexi	200795|Chloroflexi	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
REGS1_k127_5870468_1	530564.Psta_3695	9.608e-39	148.0	COG3436@1|root,COG3436@2|Bacteria,2J11P@203682|Planctomycetes	203682|Planctomycetes	L	PFAM IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
REGS1_k127_5870468_0	530564.Psta_3696	1.285e-209	666.0	COG4372@1|root,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,DUF3084,LZ_Tnp_IS66,zf-IS66
REGS1_k127_5870468_2	1408224.SAMCCGM7_c2709	5.308e-20	99.0	2FJDR@1|root,34B3I@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5870468_4	195250.CM001776_gene2834	2.1e-08	68.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,RHS_repeat,VCBS
REGS1_k127_5870734_4	1121939.L861_02465	2.057e-26	110.0	COG4310@1|root,COG4310@2|Bacteria,1NDWT@1224|Proteobacteria,1RRQM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF2172)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47
REGS1_k127_5870734_1	926562.Oweho_1399	7.049e-110	364.0	COG0451@1|root,COG0451@2|Bacteria,4NI4N@976|Bacteroidetes	976|Bacteroidetes	GM	NAD-dependent epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_5870734_0	661478.OP10G_3277	4.016e-125	419.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_5870734_3	91464.S7335_2636	5.258e-73	265.0	2F27U@1|root,33V60@2|Bacteria,1GDNF@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5870734_2	1396418.BATQ01000166_gene1923	2.695e-95	325.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K13000	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
REGS1_k127_5870734_5	497964.CfE428DRAFT_2209	1.038e-09	60.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	pssI	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,Sulfatase
REGS1_k127_5879306_1	411684.HPDFL43_01980	8.632e-108	360.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,43H5X@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
REGS1_k127_5879306_2	981384.AEYW01000001_gene1472	2.854e-86	299.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2U0D6@28211|Alphaproteobacteria,4NCGV@97050|Ruegeria	28211|Alphaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
REGS1_k127_5879306_0	1174528.JH992893_gene5997	3.795e-172	546.0	COG2017@1|root,COG2017@2|Bacteria,1GGS7@1117|Cyanobacteria	1117|Cyanobacteria	G	converts alpha-aldose to the beta-anomer	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5879306_3	35841.BT1A1_0987	4.99e-33	140.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,4HCS4@91061|Bacilli,1ZCPA@1386|Bacillus	91061|Bacilli	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_5879306_4	457421.CBFG_04356	3.817e-13	71.0	2EZ3K@1|root,33S9T@2|Bacteria,1VSQ5@1239|Firmicutes,24ZIX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5885558_6	313624.NSP_2420	4.127e-17	91.0	COG4928@1|root,COG4928@2|Bacteria,1G0KU@1117|Cyanobacteria,1HM31@1161|Nostocales	1117|Cyanobacteria	S	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
REGS1_k127_5885558_1	926550.CLDAP_08440	1.193e-61	219.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_5885558_3	926569.ANT_23300	1.073e-33	135.0	COG2001@1|root,COG2001@2|Bacteria,2G6ZC@200795|Chloroflexi	200795|Chloroflexi	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
REGS1_k127_5885558_2	926550.CLDAP_08440	1.506e-56	206.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_5885558_5	1121451.DESAM_22148	8.515e-31	141.0	COG4585@1|root,COG4585@2|Bacteria,1PG7K@1224|Proteobacteria,439XZ@68525|delta/epsilon subdivisions,2X1V5@28221|Deltaproteobacteria,2MA1M@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
REGS1_k127_5885558_7	204669.Acid345_4603	0.0008341	51.0	COG0457@1|root,COG0457@2|Bacteria,3Y35N@57723|Acidobacteria,2JHIM@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8
REGS1_k127_5885558_0	861299.J421_2299	1.237e-68	243.0	COG4127@1|root,COG4127@2|Bacteria,1ZV3T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Mrr_cat
REGS1_k127_5885558_4	926569.ANT_30350	1.559e-33	137.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_30350|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5905942_2	446470.Snas_3888	7.684e-14	73.0	COG0702@1|root,COG0702@2|Bacteria,2GK1A@201174|Actinobacteria,4EZGJ@85014|Glycomycetales	201174|Actinobacteria	GM	PFAM NmrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
REGS1_k127_5905942_1	926569.ANT_13710	8.59e-106	350.0	COG0179@1|root,COG0179@2|Bacteria,2G6H8@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2437,FAA_hydrolase
REGS1_k127_5905942_0	926569.ANT_14870	1.661e-180	575.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
REGS1_k127_5923446_3	388739.RSK20926_21215	4.753e-53	192.0	COG1176@1|root,COG1176@2|Bacteria,1PFEG@1224|Proteobacteria,2V9DK@28211|Alphaproteobacteria,2P4WC@2433|Roseobacter	28211|Alphaproteobacteria	P	COG1176 ABC-type spermidine putrescine transport system, permease component I	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
REGS1_k127_5923446_1	935261.JAGL01000005_gene3409	5.626e-57	212.0	COG1177@1|root,COG1177@2|Bacteria,1MVC5@1224|Proteobacteria,2TRRJ@28211|Alphaproteobacteria,43H7C@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
REGS1_k127_5923446_2	586416.GZ22_13910	1.051e-56	212.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli	91061|Bacilli	P	spermidine putrescine ABC transporter	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iSB619.SA_RS05395	SBP_bac_8
REGS1_k127_5923446_0	204669.Acid345_3113	1.065e-137	449.0	COG0665@1|root,COG0665@2|Bacteria,3Y8UA@57723|Acidobacteria	57723|Acidobacteria	E	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO
REGS1_k127_594972_1	794903.OPIT5_14440	2.908e-91	306.0	COG0439@1|root,COG0439@2|Bacteria,46SIE@74201|Verrucomicrobia,3K78R@414999|Opitutae	74201|Verrucomicrobia	I	acetyl-CoA carboxylase	-	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
REGS1_k127_594972_0	926550.CLDAP_21610	4.793e-242	765.0	COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi	200795|Chloroflexi	I	PFAM carboxyl transferase	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
REGS1_k127_594972_2	926569.ANT_00730	4.993e-83	301.0	COG1287@1|root,COG1287@2|Bacteria,2G9P1@200795|Chloroflexi	200795|Chloroflexi	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_594972_3	926550.CLDAP_21600	4.29e-66	232.0	COG0604@1|root,COG0604@2|Bacteria,2G6DS@200795|Chloroflexi	200795|Chloroflexi	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_5982753_0	497964.CfE428DRAFT_0631	1.921e-184	601.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
REGS1_k127_6004886_3	926569.ANT_03400	1.34e-08	59.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_6004886_0	926569.ANT_10570	3.188e-319	992.0	COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi	200795|Chloroflexi	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
REGS1_k127_6004886_1	926569.ANT_10580	3.193e-30	121.0	COG0184@1|root,COG0184@2|Bacteria,2G791@200795|Chloroflexi	200795|Chloroflexi	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
REGS1_k127_6004886_2	485913.Krac_9014	6.593e-13	71.0	COG0846@1|root,COG0846@2|Bacteria	2|Bacteria	K	NAD+ binding	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
REGS1_k127_6015299_1	759914.BP951000_1517	4.263e-06	55.0	COG0457@1|root,COG0457@2|Bacteria	759914.BP951000_1517|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6015299_0	981369.JQMJ01000001_gene7013	9.36e-54	201.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria,2NMDB@228398|Streptacidiphilus	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_29,HTH_32
REGS1_k127_6020067_1	309801.trd_0039	6.425e-100	333.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,27Y45@189775|Thermomicrobia	189775|Thermomicrobia	C	Acyl- CoA dehydrogenase type 2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_6020067_0	926569.ANT_03530	5.116e-255	795.0	COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi	200795|Chloroflexi	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
REGS1_k127_6022874_4	518766.Rmar_0472	3.791e-123	405.0	COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,1FIXF@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Transketolase, thiamine diphosphate binding domain	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
REGS1_k127_6022874_13	326427.Cagg_0605	3.066e-51	190.0	COG3186@1|root,COG3186@2|Bacteria,2GAHQ@200795|Chloroflexi,37677@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aromatic amino acid hydroxylase	-	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
REGS1_k127_6022874_15	1499967.BAYZ01000145_gene6206	4.052e-27	115.0	COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
REGS1_k127_6022874_16	425104.Ssed_1079	2.946e-20	97.0	COG0801@1|root,COG0801@2|Bacteria,1RHNN@1224|Proteobacteria,1S62M@1236|Gammaproteobacteria,2QBJS@267890|Shewanellaceae	1236|Gammaproteobacteria	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK2	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
REGS1_k127_6022874_10	1128421.JAGA01000002_gene938	5.111e-69	241.0	COG0302@1|root,COG0302@2|Bacteria,2NPAT@2323|unclassified Bacteria	2|Bacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
REGS1_k127_6022874_12	926569.ANT_20690	2.42e-53	194.0	COG1544@1|root,COG1544@2|Bacteria,2G6Z4@200795|Chloroflexi	200795|Chloroflexi	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
REGS1_k127_6022874_14	335543.Sfum_3894	1.897e-41	162.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2MRUJ@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
REGS1_k127_6022874_6	926569.ANT_20670	5.53e-107	356.0	COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi	200795|Chloroflexi	NU	PFAM type II secretion system protein	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
REGS1_k127_6022874_7	926569.ANT_20660	6.07e-97	330.0	COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
REGS1_k127_6022874_0	926569.ANT_20650	6.64e-223	700.0	COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi	200795|Chloroflexi	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
REGS1_k127_6022874_1	926569.ANT_20640	2.435e-150	486.0	COG2201@1|root,COG4963@1|root,COG2201@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi	200795|Chloroflexi	D	PFAM response regulator receiver	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA,Response_reg
REGS1_k127_6022874_11	926569.ANT_20630	6.076e-59	218.0	COG3745@1|root,COG3745@2|Bacteria	2|Bacteria	U	Flp pilus assembly protein CpaB	cpaB	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
REGS1_k127_6022874_2	926569.ANT_17720	1.407e-146	478.0	COG0124@1|root,COG0124@2|Bacteria,2G64E@200795|Chloroflexi	200795|Chloroflexi	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
REGS1_k127_6022874_17	58123.JOFJ01000014_gene5033	4.15e-19	93.0	COG0664@1|root,COG0664@2|Bacteria,2IRJW@201174|Actinobacteria,4EQ5B@85012|Streptosporangiales	201174|Actinobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_6022874_5	1123242.JH636435_gene1526	7.797e-113	376.0	COG0479@1|root,COG0479@2|Bacteria,2IWTB@203682|Planctomycetes	203682|Planctomycetes	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
REGS1_k127_6022874_9	344747.PM8797T_02809	3.659e-90	307.0	COG0543@1|root,COG0543@2|Bacteria,2IYBB@203682|Planctomycetes	203682|Planctomycetes	C	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
REGS1_k127_6022874_8	518766.Rmar_2589	1.055e-91	308.0	COG1941@1|root,COG1941@2|Bacteria	2|Bacteria	C	coenzyme F420 hydrogenase activity	hoxY	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
REGS1_k127_6022874_3	272134.KB731324_gene5864	1.056e-137	450.0	COG3259@1|root,COG3259@2|Bacteria,1G1C8@1117|Cyanobacteria,1H7NU@1150|Oscillatoriales	1117|Cyanobacteria	C	Coenzyme F420-reducing hydrogenase, alpha subunit	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
REGS1_k127_6026727_1	196490.AUEZ01000042_gene7227	1.38e-131	427.0	COG1529@1|root,COG1529@2|Bacteria,1MUEA@1224|Proteobacteria,2TQMW@28211|Alphaproteobacteria,3JSZE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
REGS1_k127_6026727_4	926569.ANT_05700	3.496e-74	255.0	COG2080@1|root,COG2080@2|Bacteria,2G8E9@200795|Chloroflexi	200795|Chloroflexi	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
REGS1_k127_6026727_2	926569.ANT_05690	2.127e-91	309.0	COG1319@1|root,COG1319@2|Bacteria	2|Bacteria	C	xanthine dehydrogenase activity	-	-	1.2.5.3,1.5.99.4	ko:K03519,ko:K19818	ko00760,ko01120,map00760,map01120	M00810	R02860,R07946,R11168	RC00589,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
REGS1_k127_6026727_5	479434.Sthe_3097	8.009e-17	87.0	2BQKI@1|root,32JGJ@2|Bacteria,2G9SN@200795|Chloroflexi,27YIJ@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF1572)	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_6026727_3	926569.ANT_05740	1.286e-74	264.0	COG0702@1|root,COG0702@2|Bacteria,2G78J@200795|Chloroflexi	200795|Chloroflexi	GM	PFAM NmrA family protein	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
REGS1_k127_6026727_0	926569.ANT_05680	6.546e-162	511.0	COG1878@1|root,COG1878@2|Bacteria,2G8DE@200795|Chloroflexi	2|Bacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
REGS1_k127_6030062_0	1469607.KK073768_gene1009	1.465e-91	319.0	COG3039@1|root,COG3039@2|Bacteria,1G3YX@1117|Cyanobacteria	1117|Cyanobacteria	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	ko:K07481	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DUF772
REGS1_k127_6030062_1	42256.RradSPS_0358	5.853e-84	299.0	COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
REGS1_k127_6042115_24	1041930.Mtc_2235	7.341e-08	54.0	COG2414@1|root,arCOG00706@2157|Archaea,2XTUP@28890|Euryarchaeota,2N9BJ@224756|Methanomicrobia	224756|Methanomicrobia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	aor-2	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
REGS1_k127_6042115_5	926569.ANT_20460	1.483e-156	511.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2G5Y8@200795|Chloroflexi	200795|Chloroflexi	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
REGS1_k127_6042115_4	926569.ANT_20590	4.637e-164	522.0	COG4260@1|root,COG4260@2|Bacteria,2G6J2@200795|Chloroflexi	200795|Chloroflexi	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,HTH_17,zinc_ribbon_2
REGS1_k127_6042115_11	926569.ANT_14480	2.567e-102	342.0	COG1975@1|root,COG1975@2|Bacteria,2G6H0@200795|Chloroflexi	200795|Chloroflexi	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
REGS1_k127_6042115_23	194439.CT0636	2.192e-17	94.0	COG0823@1|root,COG0823@2|Bacteria,1FEIQ@1090|Chlorobi	1090|Chlorobi	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
REGS1_k127_6042115_16	357808.RoseRS_4240	1.103e-44	181.0	COG1807@1|root,COG1807@2|Bacteria,2G7Q8@200795|Chloroflexi,3782W@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6042115_0	926569.ANT_14470	0.0	1449.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G5NF@200795|Chloroflexi	200795|Chloroflexi	C	COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs	xdh	-	-	ko:K12528	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
REGS1_k127_6042115_6	1047013.AQSP01000100_gene587	4.787e-149	482.0	COG2271@1|root,COG2271@2|Bacteria	2|Bacteria	G	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_6042115_19	926550.CLDAP_18620	6.906e-33	133.0	COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
REGS1_k127_6042115_10	525897.Dbac_0080	5.36e-105	348.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria,2M987@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM RarD protein, DMT superfamily transporter	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
REGS1_k127_6042115_9	720554.Clocl_3061	1.574e-111	374.0	COG0451@1|root,COG0451@2|Bacteria,1TPYA@1239|Firmicutes,24A39@186801|Clostridia,3WHQG@541000|Ruminococcaceae	186801|Clostridia	GM	NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_6042115_3	204669.Acid345_1623	3.24e-195	615.0	COG0205@1|root,COG0205@2|Bacteria,3Y4A9@57723|Acidobacteria,2JKQ8@204432|Acidobacteriia	204432|Acidobacteriia	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
REGS1_k127_6042115_22	1449126.JQKL01000002_gene1553	3.174e-20	97.0	COG0680@1|root,COG0680@2|Bacteria	2|Bacteria	C	spore germination	hybD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
REGS1_k127_6042115_2	909663.KI867150_gene1871	3.525e-230	721.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42N63@68525|delta/epsilon subdivisions,2WJPA@28221|Deltaproteobacteria,2MQRM@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM nickel-dependent hydrogenase, large subunit	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
REGS1_k127_6042115_7	1379698.RBG1_1C00001G0048	1.205e-112	375.0	COG1941@1|root,COG1941@2|Bacteria,2NQP6@2323|unclassified Bacteria	2|Bacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Fe_hyd_lg_C,Fer4,FlpD,Oxidored_q6
REGS1_k127_6042115_15	429009.Adeg_1784	2.142e-54	195.0	COG1894@1|root,COG1908@1|root,COG1894@2|Bacteria,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,42GG4@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,NADH_4Fe-4S
REGS1_k127_6042115_1	693661.Arcve_1567	4.51e-244	771.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_6042115_14	1379698.RBG1_1C00001G0051	4.501e-72	260.0	COG2048@1|root,COG2048@2|Bacteria,2NQP7@2323|unclassified Bacteria	2|Bacteria	C	Heterodisulfide reductase subunit B	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
REGS1_k127_6042115_18	1449126.JQKL01000002_gene1547	5.351e-34	138.0	COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
REGS1_k127_6042115_8	926569.ANT_03090	3.185e-112	372.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
REGS1_k127_6042115_12	926569.ANT_03090	1.078e-97	330.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
REGS1_k127_6042115_17	926569.ANT_03100	2.927e-39	156.0	2BBY6@1|root,325GN@2|Bacteria,2G746@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6042115_13	926569.ANT_19030	5.878e-90	301.0	COG2220@1|root,COG2220@2|Bacteria,2G6IQ@200795|Chloroflexi	200795|Chloroflexi	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
REGS1_k127_6042115_21	926569.ANT_19040	2.829e-31	125.0	2EUFH@1|root,31CAS@2|Bacteria,2G9NZ@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6042115_25	344747.PM8797T_16887	0.0003527	54.0	COG1807@1|root,COG1807@2|Bacteria,2IZ75@203682|Planctomycetes	203682|Planctomycetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_6042115_20	292459.STH1727	4.243e-32	128.0	COG1051@1|root,COG1194@1|root,COG1051@2|Bacteria,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia	186801|Clostridia	L	A G-specific adenine glycosylase	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
REGS1_k127_6050317_3	1158050.KB895455_gene1724	1.205e-33	131.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
REGS1_k127_6050317_4	926569.ANT_04790	8.754e-16	86.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	3.5.1.104	ko:K07273,ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_25,LysM
REGS1_k127_6050317_2	926569.ANT_04780	1.079e-47	179.0	COG0494@1|root,COG0494@2|Bacteria,2G7A1@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
REGS1_k127_6050317_0	926569.ANT_28320	0.0	1358.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
REGS1_k127_6052389_1	1379270.AUXF01000003_gene3886	4.369e-157	501.0	COG1089@1|root,COG1089@2|Bacteria,1ZSR1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_6052389_4	926569.ANT_00620	7.423e-97	329.0	COG0438@1|root,COG0438@2|Bacteria,2G9D7@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4
REGS1_k127_6052389_14	1163398.AJJP01000217_gene3045	5.235e-07	62.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C
REGS1_k127_6052389_2	926569.ANT_31620	5.534e-124	404.0	COG0451@1|root,COG0451@2|Bacteria,2G6S4@200795|Chloroflexi	200795|Chloroflexi	M	Short-chain dehydrogenase reductase SDR	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
REGS1_k127_6052389_0	926569.ANT_31630	3.302e-205	647.0	COG0677@1|root,COG0677@2|Bacteria,2G5PP@200795|Chloroflexi	200795|Chloroflexi	M	PFAM UDP-glucose GDP-mannose dehydrogenase	-	-	1.1.1.136	ko:K13015	ko00520,map00520	-	R00421	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
REGS1_k127_6052389_7	926569.ANT_31640	9.521e-77	263.0	COG1573@1|root,COG1573@2|Bacteria,2G6BR@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM phage SPO1 DNA polymerase-related protein	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_6052389_10	926569.ANT_31650	8.971e-38	147.0	COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi	200795|Chloroflexi	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
REGS1_k127_6052389_8	926569.ANT_31660	2.571e-65	233.0	COG1214@1|root,COG1214@2|Bacteria,2G6VT@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase M22 glycoprotease	-	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_6052389_9	926569.ANT_31670	6.039e-63	220.0	COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi	200795|Chloroflexi	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
REGS1_k127_6052389_3	1035308.AQYY01000002_gene479	1.68e-110	369.0	COG0707@1|root,COG0707@2|Bacteria,1UZ4A@1239|Firmicutes,249EE@186801|Clostridia	186801|Clostridia	M	PFAM Monogalactosyldiacylglycerol synthase	-	-	2.4.1.315	ko:K03429	ko00561,ko01100,map00561,map01100	-	R02689,R04377	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT28	-	Glyco_tran_28_C,Glyco_trans_1_4,MGDG_synth
REGS1_k127_6052389_13	479434.Sthe_0412	9.833e-22	96.0	COG4481@1|root,COG4481@2|Bacteria,2G9W8@200795|Chloroflexi,27YMV@189775|Thermomicrobia	189775|Thermomicrobia	S	Bacterial protein of unknown function (DUF951)	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
REGS1_k127_6052389_5	926569.ANT_00640	3.511e-88	294.0	COG0503@1|root,COG0503@2|Bacteria,2G8J8@200795|Chloroflexi	200795|Chloroflexi	F	Phosphoribosyl transferase domain	-	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
REGS1_k127_6052389_11	926569.ANT_00650	1.207e-24	109.0	COG2827@1|root,COG2827@2|Bacteria,2G9H6@200795|Chloroflexi	200795|Chloroflexi	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
REGS1_k127_6052389_12	926569.ANT_00660	7.033e-22	103.0	COG0287@1|root,COG0287@2|Bacteria,2G9BH@200795|Chloroflexi	200795|Chloroflexi	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
REGS1_k127_6065252_20	926569.ANT_03400	9.066e-16	80.0	COG0477@1|root,COG2814@2|Bacteria,2GA6M@200795|Chloroflexi	200795|Chloroflexi	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_6065252_12	485913.Krac_0932	1.384e-60	216.0	COG1670@1|root,COG1670@2|Bacteria,2G6X6@200795|Chloroflexi	200795|Chloroflexi	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
REGS1_k127_6065252_2	926569.ANT_10550	4.217e-205	651.0	COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_6065252_11	1144275.COCOR_04108	3.123e-61	218.0	COG2085@1|root,COG2085@2|Bacteria,1NF95@1224|Proteobacteria,4380B@68525|delta/epsilon subdivisions,2X3AC@28221|Deltaproteobacteria,2YURK@29|Myxococcales	28221|Deltaproteobacteria	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
REGS1_k127_6065252_15	1150474.JQJI01000025_gene1664	4.6e-39	158.0	COG1394@1|root,COG1394@2|Bacteria,2GD6P@200918|Thermotogae	200918|Thermotogae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
REGS1_k127_6065252_3	1499967.BAYZ01000009_gene5291	3.023e-190	605.0	COG1156@1|root,COG1156@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
REGS1_k127_6065252_0	1499967.BAYZ01000009_gene5290	1.855e-241	759.0	COG1155@1|root,COG1155@2|Bacteria,2NNYK@2323|unclassified Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
REGS1_k127_6065252_19	186497.PF0179	5.724e-17	89.0	COG1390@1|root,arCOG00869@2157|Archaea,2XWGX@28890|Euryarchaeota,243A6@183968|Thermococci	183968|Thermococci	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
REGS1_k127_6065252_22	869209.Tresu_1622	2.181e-11	68.0	COG1436@1|root,COG1436@2|Bacteria,2J8AJ@203691|Spirochaetes	203691|Spirochaetes	C	-ATPase subunit F	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
REGS1_k127_6065252_18	663278.Ethha_2017	1.235e-18	91.0	COG0636@1|root,COG0636@2|Bacteria,1VF4U@1239|Firmicutes,25CR4@186801|Clostridia,3WJIE@541000|Ruminococcaceae	186801|Clostridia	C	ATP synthase subunit C	ntpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
REGS1_k127_6065252_8	1499967.BAYZ01000009_gene5286	3.614e-90	324.0	COG1269@1|root,COG1269@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
REGS1_k127_6065252_13	1499967.BAYZ01000009_gene5285	4.148e-44	174.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
REGS1_k127_6065252_24	1151117.AJLF01000002_gene233	8.658e-05	49.0	COG2811@1|root,arCOG03363@2157|Archaea,2Y4VV@28890|Euryarchaeota,244QM@183968|Thermococci	183968|Thermococci	C	H subunit	-	-	-	ko:K02107	ko00190,map00190	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
REGS1_k127_6065252_10	926569.ANT_10540	5.143e-74	256.0	COG0711@1|root,COG0712@1|root,COG0711@2|Bacteria,COG0712@2|Bacteria,2G76T@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
REGS1_k127_6065252_16	926569.ANT_10530	2.537e-32	126.0	COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi	200795|Chloroflexi	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
REGS1_k127_6065252_9	926569.ANT_10520	2.034e-87	299.0	COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi	200795|Chloroflexi	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
REGS1_k127_6065252_5	926569.ANT_10480	1.842e-138	454.0	COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
REGS1_k127_6065252_4	1128421.JAGA01000002_gene1909	6.257e-144	472.0	COG1008@1|root,COG1008@2|Bacteria,2NQKN@2323|unclassified Bacteria	2|Bacteria	C	Proton-conducting membrane transporter	ndhD	-	1.6.5.3	ko:K00342,ko:K05575	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iJN678.ndhD2	Oxidored_q5_N,Proton_antipo_M
REGS1_k127_6065252_1	926569.ANT_10460	5.069e-215	677.0	COG1008@1|root,COG1008@2|Bacteria,2G5VU@200795|Chloroflexi	200795|Chloroflexi	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
REGS1_k127_6065252_6	161156.JQKW01000009_gene1593	2.633e-131	445.0	COG1009@1|root,COG1009@2|Bacteria,2GHMS@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CP	NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
REGS1_k127_6065252_17	926550.CLDAP_08800	5.803e-30	123.0	COG0713@1|root,COG0713@2|Bacteria,2G782@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340,ko:K05576	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
REGS1_k127_6065252_21	512565.AMIS_2920	5.758e-13	77.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4D9YY@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
REGS1_k127_6065252_7	926569.ANT_10420	6.02e-104	351.0	COG1005@1|root,COG1005@2|Bacteria,2G60S@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
REGS1_k127_6065252_14	926569.ANT_10410	7.984e-43	161.0	COG0838@1|root,COG0838@2|Bacteria,2G71E@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
REGS1_k127_6070301_0	1123073.KB899242_gene1305	5.61e-58	206.0	COG5646@1|root,COG5646@2|Bacteria,1QB2A@1224|Proteobacteria,1T6JI@1236|Gammaproteobacteria,1X7N4@135614|Xanthomonadales	135614|Xanthomonadales	S	InterPro IPR014922	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
REGS1_k127_6070301_2	1140.Synpcc7942_1067	3.049e-13	78.0	COG3722@1|root,COG3722@2|Bacteria,1GEGF@1117|Cyanobacteria	1117|Cyanobacteria	K	fumarate hydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4145
REGS1_k127_6070301_3	555500.I215_05712	1.487e-06	57.0	COG2318@1|root,COG2318@2|Bacteria,4NRAP@976|Bacteroidetes,1I3NC@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_6070301_1	670487.Ocepr_1254	3.99e-44	169.0	2DN4A@1|root,32VFK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6070301_4	118161.KB235922_gene474	9.515e-05	50.0	COG2319@1|root,COG2319@2|Bacteria,1G4U3@1117|Cyanobacteria,3VIQN@52604|Pleurocapsales	1117|Cyanobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,WD40
REGS1_k127_6105971_12	1122947.FR7_3972	1.017e-61	223.0	COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H46S@909932|Negativicutes	909932|Negativicutes	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	-	ko:K03387	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_6105971_1	1480694.DC28_13880	3.954e-194	617.0	COG0281@1|root,COG0281@2|Bacteria,2J5DN@203691|Spirochaetes	203691|Spirochaetes	C	Malic enzyme, NAD binding domain	mdh	-	1.1.1.38,1.1.1.40	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	M00169,M00172	R00214,R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
REGS1_k127_6105971_11	1232410.KI421424_gene1692	1.468e-70	259.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,43V05@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF-1	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
REGS1_k127_6105971_0	555779.Dthio_PD3239	5.421e-207	668.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
REGS1_k127_6105971_16	1298880.AUEV01000016_gene2142	2.294e-06	56.0	COG3832@1|root,COG3832@2|Bacteria,2IHP6@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
REGS1_k127_6105971_15	525897.Dbac_0803	4.755e-12	69.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria,2MCID@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
REGS1_k127_6105971_14	1123401.JHYQ01000026_gene3279	2.557e-18	87.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,1SCKA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
REGS1_k127_6105971_13	926569.ANT_28790	1.869e-61	222.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
REGS1_k127_6105971_6	926569.ANT_28800	1.13e-138	451.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_6105971_5	926569.ANT_28810	2.334e-173	549.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
REGS1_k127_6105971_2	926569.ANT_28820	2.344e-184	593.0	COG1257@1|root,COG1257@2|Bacteria,2G5QV@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the HMG-CoA reductase family	mvaA	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
REGS1_k127_6105971_4	926569.ANT_24720	2.524e-176	568.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G88D@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_3
REGS1_k127_6105971_3	926569.ANT_19080	1.438e-181	578.0	COG0593@1|root,COG0593@2|Bacteria,2G5W8@200795|Chloroflexi	200795|Chloroflexi	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
REGS1_k127_6105971_7	926569.ANT_31030	1.684e-119	394.0	COG0052@1|root,COG0052@2|Bacteria,2G5J2@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
REGS1_k127_6105971_10	926569.ANT_31020	4.924e-72	251.0	COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi	200795|Chloroflexi	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
REGS1_k127_6105971_8	926569.ANT_31010	6.014e-101	334.0	COG0528@1|root,COG0528@2|Bacteria,2G5RG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
REGS1_k127_6105971_9	926569.ANT_03510	1.405e-77	263.0	COG0233@1|root,COG0233@2|Bacteria,2G6FY@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
REGS1_k127_6106011_0	1116369.KB890025_gene5021	1.606e-14	81.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2TTB8@28211|Alphaproteobacteria,43IRY@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport	MA20_34190	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
REGS1_k127_6121261_0	1038859.AXAU01000025_gene4067	3.747e-164	530.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2TU7H@28211|Alphaproteobacteria,3JSWU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	J	Amidase	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
REGS1_k127_6121261_1	632245.CLP_0660	1.158e-05	48.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,36DME@31979|Clostridiaceae	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
REGS1_k127_6122498_2	351016.RAZWK3B_13899	4.406e-07	61.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
REGS1_k127_6122498_1	710696.Intca_1127	4.691e-10	72.0	COG4409@1|root,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR,BNR_2,DUF11,SBBP
REGS1_k127_6122498_0	886293.Sinac_2020	3.538e-12	66.0	COG0364@1|root,COG0364@2|Bacteria,2IYER@203682|Planctomycetes	203682|Planctomycetes	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
REGS1_k127_6139745_1	266117.Rxyl_1005	2.906e-126	417.0	28HJF@1|root,2Z7UK@2|Bacteria,2ICK7@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6139745_3	671143.DAMO_1476	2.147e-28	116.0	COG5470@1|root,COG5470@2|Bacteria,2NQ81@2323|unclassified Bacteria	2|Bacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
REGS1_k127_6139745_2	765910.MARPU_14415	2.062e-48	180.0	COG0457@1|root,COG0457@2|Bacteria,1N4EF@1224|Proteobacteria,1SRCF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6139745_0	926569.ANT_10860	0.0	1551.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi	200795|Chloroflexi	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
REGS1_k127_6156306_0	1267535.KB906767_gene5230	3.661e-162	528.0	COG0501@1|root,COG0501@2|Bacteria,3Y3FX@57723|Acidobacteria,2JHYR@204432|Acidobacteriia	204432|Acidobacteriia	O	Belongs to the peptidase M48B family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_6156306_1	204669.Acid345_4767	2.181e-45	167.0	COG2329@1|root,COG2329@2|Bacteria,3Y5V2@57723|Acidobacteria,2JK53@204432|Acidobacteriia	204432|Acidobacteriia	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6156306_3	1042375.AFPL01000048_gene3779	0.0003928	52.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1MX32@1224|Proteobacteria,1S0RD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
REGS1_k127_6172760_0	926569.ANT_14870	2.445e-239	757.0	COG0112@1|root,COG0404@1|root,COG0112@2|Bacteria,COG0404@2|Bacteria,2G624@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
REGS1_k127_6172760_1	7739.XP_002589078.1	1.738e-16	85.0	COG3119@1|root,KOG3731@2759|Eukaryota,38FCG@33154|Opisthokonta,3BBI1@33208|Metazoa,3CU4U@33213|Bilateria,480KF@7711|Chordata	33208|Metazoa	G	esophagus smooth muscle contraction	SULF1	GO:0000902,GO:0000904,GO:0001501,GO:0001502,GO:0001655,GO:0001817,GO:0001819,GO:0001822,GO:0001889,GO:0001936,GO:0001937,GO:0002062,GO:0002063,GO:0003002,GO:0003008,GO:0003012,GO:0003014,GO:0003094,GO:0003156,GO:0003674,GO:0003824,GO:0004065,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005794,GO:0005795,GO:0005886,GO:0006022,GO:0006029,GO:0006082,GO:0006355,GO:0006357,GO:0006790,GO:0006807,GO:0006928,GO:0006935,GO:0006936,GO:0006939,GO:0006950,GO:0007154,GO:0007155,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007389,GO:0007399,GO:0007409,GO:0007411,GO:0007444,GO:0007447,GO:0007450,GO:0008037,GO:0008038,GO:0008039,GO:0008045,GO:0008146,GO:0008150,GO:0008152,GO:0008284,GO:0008285,GO:0008449,GO:0008484,GO:0008589,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009605,GO:0009611,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009953,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010468,GO:0010556,GO:0010574,GO:0010575,GO:0010646,GO:0010647,GO:0010648,GO:0012505,GO:0014831,GO:0014846,GO:0015012,GO:0015015,GO:0016020,GO:0016043,GO:0016201,GO:0016525,GO:0016740,GO:0016782,GO:0016787,GO:0016788,GO:0017095,GO:0019219,GO:0019222,GO:0019538,GO:0021675,GO:0022008,GO:0022603,GO:0022610,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030111,GO:0030154,GO:0030166,GO:0030177,GO:0030178,GO:0030182,GO:0030198,GO:0030201,GO:0030202,GO:0030203,GO:0030334,GO:0030336,GO:0030510,GO:0030513,GO:0031099,GO:0031100,GO:0031175,GO:0031323,GO:0031326,GO:0031984,GO:0032501,GO:0032502,GO:0032835,GO:0032836,GO:0032879,GO:0032989,GO:0032990,GO:0034483,GO:0034645,GO:0035107,GO:0035108,GO:0035220,GO:0035222,GO:0035295,GO:0035860,GO:0036022,GO:0040011,GO:0040012,GO:0040013,GO:0040036,GO:0040037,GO:0042058,GO:0042059,GO:0042127,GO:0042221,GO:0042330,GO:0043009,GO:0043062,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044281,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045121,GO:0045765,GO:0045879,GO:0045880,GO:0045992,GO:0045995,GO:0048010,GO:0048190,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048660,GO:0048661,GO:0048666,GO:0048667,GO:0048699,GO:0048705,GO:0048706,GO:0048731,GO:0048732,GO:0048736,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050678,GO:0050680,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0050919,GO:0051093,GO:0051171,GO:0051216,GO:0051239,GO:0051240,GO:0051241,GO:0051252,GO:0051270,GO:0051271,GO:0051716,GO:0060173,GO:0060255,GO:0060348,GO:0060384,GO:0060429,GO:0060685,GO:0060686,GO:0060688,GO:0060828,GO:0061008,GO:0061448,GO:0061564,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072001,GO:0072006,GO:0080090,GO:0090090,GO:0090092,GO:0090100,GO:0090263,GO:0090287,GO:0090288,GO:0097205,GO:0097421,GO:0097485,GO:0098589,GO:0098743,GO:0098791,GO:0098805,GO:0098857,GO:0120036,GO:0120039,GO:1901135,GO:1901137,GO:1901184,GO:1901185,GO:1901342,GO:1901343,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1903510,GO:1905330,GO:1905331,GO:2000026,GO:2000027,GO:2000112,GO:2000145,GO:2000146,GO:2000181,GO:2000241,GO:2000242,GO:2000345,GO:2001141	-	ko:K14607	-	-	-	-	ko00000,ko01000	-	-	-	DUF3740,Sulfatase
REGS1_k127_6173460_17	1122917.KB899659_gene5939	5.311e-08	56.0	COG4585@1|root,COG4585@2|Bacteria,1UZXT@1239|Firmicutes,4HB4Q@91061|Bacilli,26S1J@186822|Paenibacillaceae	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K11617	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA_3
REGS1_k127_6173460_7	926550.CLDAP_08440	3.675e-72	250.0	COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_6173460_16	429009.Adeg_1040	1.633e-16	85.0	COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,1UF2S@1239|Firmicutes,248CD@186801|Clostridia,42FVJ@68295|Thermoanaerobacterales	186801|Clostridia	D	ATPase MipZ	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,ParA,Response_reg
REGS1_k127_6173460_12	926569.ANT_13140	3.298e-42	162.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_6173460_11	926569.ANT_22780	7.074e-45	172.0	COG1047@1|root,COG1047@2|Bacteria,2G744@200795|Chloroflexi	200795|Chloroflexi	G	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_6173460_2	383372.Rcas_0998	5.493e-106	357.0	COG0153@1|root,COG0153@2|Bacteria,2G6CE@200795|Chloroflexi,375CJ@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
REGS1_k127_6173460_5	926569.ANT_10920	2.206e-84	288.0	COG0095@1|root,COG0095@2|Bacteria,2G6P9@200795|Chloroflexi	200795|Chloroflexi	H	PFAM Biotin lipoate A B protein ligase	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
REGS1_k127_6173460_9	326427.Cagg_1818	7.242e-50	190.0	COG0329@1|root,COG0329@2|Bacteria,2G6U3@200795|Chloroflexi,375WI@32061|Chloroflexia	32061|Chloroflexia	EM	PFAM dihydrodipicolinate synthetase	-	-	3.5.4.22,4.3.3.7	ko:K01714,ko:K21062	ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R02280,R10147	RC00679,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
REGS1_k127_6173460_8	1128421.JAGA01000001_gene2083	1.035e-71	256.0	COG1475@1|root,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria	2|Bacteria	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,ParBc
REGS1_k127_6173460_10	326427.Cagg_0444	4.471e-49	184.0	COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi,375QR@32061|Chloroflexia	32061|Chloroflexia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
REGS1_k127_6173460_0	926569.ANT_15160	2.545e-278	876.0	COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2G5NM@200795|Chloroflexi	200795|Chloroflexi	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PQQ_3,Pkinase
REGS1_k127_6173460_6	926569.ANT_15150	3.813e-77	272.0	COG0631@1|root,COG0631@2|Bacteria,2G8RD@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
REGS1_k127_6173460_3	926569.ANT_15140	3.588e-101	347.0	COG0484@1|root,COG2304@1|root,COG0484@2|Bacteria,COG2304@2|Bacteria,2G8H5@200795|Chloroflexi	200795|Chloroflexi	O	PFAM von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
REGS1_k127_6173460_13	926569.ANT_15130	4.146e-34	139.0	COG1716@1|root,COG1716@2|Bacteria,2G9CS@200795|Chloroflexi	200795|Chloroflexi	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
REGS1_k127_6173460_15	926569.ANT_15120	1.534e-19	94.0	2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6173460_4	383372.Rcas_4344	7.039e-97	321.0	COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,376TC@32061|Chloroflexia	32061|Chloroflexia	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_6173460_14	926550.CLDAP_01300	3.922e-31	127.0	COG0071@1|root,COG0071@2|Bacteria,2G71M@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
REGS1_k127_6173460_1	926569.ANT_14300	3.016e-106	350.0	COG2197@1|root,COG2197@2|Bacteria,2G80G@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_6174219_1	330214.NIDE4341	4.475e-88	292.0	COG1249@1|root,COG1249@2|Bacteria,3J11P@40117|Nitrospirae	40117|Nitrospirae	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_6174219_2	330214.NIDE4340	8.406e-78	268.0	COG0457@1|root,COG0457@2|Bacteria	330214.NIDE4340|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6174219_0	330214.NIDE4337	1.174e-117	383.0	COG0668@1|root,COG0668@2|Bacteria	2|Bacteria	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
REGS1_k127_617806_1	926569.ANT_24820	1.756e-143	467.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
REGS1_k127_617806_7	1120985.AUMI01000004_gene1316	2.094e-66	235.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,4H3CN@909932|Negativicutes	909932|Negativicutes	E	Allophanate hydrolase subunit 1	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
REGS1_k127_617806_6	345219.Bcoa_1683	1.275e-67	241.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,4HACC@91061|Bacilli,1ZCFE@1386|Bacillus	91061|Bacilli	E	Allophanate hydrolase subunit 2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
REGS1_k127_617806_5	926569.ANT_23200	4.139e-88	297.0	COG1540@1|root,COG1540@2|Bacteria,2G8DT@200795|Chloroflexi	200795|Chloroflexi	S	Belongs to the UPF0271 (lamB) family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
REGS1_k127_617806_9	926569.ANT_27670	3.119e-44	182.0	COG4713@1|root,COG4713@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
REGS1_k127_617806_3	926569.ANT_24710	3.854e-102	335.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
REGS1_k127_617806_2	926569.ANT_25850	2.626e-112	374.0	COG0265@1|root,COG0265@2|Bacteria,2G6KG@200795|Chloroflexi	200795|Chloroflexi	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_617806_4	926569.ANT_25840	5.467e-100	334.0	COG0484@1|root,COG0484@2|Bacteria,2G61V@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock protein DnaJ domain protein	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
REGS1_k127_617806_8	1112217.PPL19_23359	6.647e-58	211.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,1S4C3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
REGS1_k127_617806_10	1408444.JHYC01000004_gene698	8.351e-20	100.0	COG0726@1|root,COG0726@2|Bacteria,1NHC2@1224|Proteobacteria,1SGBD@1236|Gammaproteobacteria,1JCCV@118969|Legionellales	118969|Legionellales	G	Protein of unknown function (DUF3298)	yjeA	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
REGS1_k127_617806_0	926569.ANT_14570	1.952e-297	935.0	COG1111@1|root,COG1205@1|root,COG1403@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,COG1403@2|Bacteria,2G605@200795|Chloroflexi	200795|Chloroflexi	L	DEAD DEAH box helicase domain protein	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,HNH,Helicase_C
REGS1_k127_6178187_3	926569.ANT_01420	4.167e-16	84.0	COG0745@1|root,COG0745@2|Bacteria	926569.ANT_01420|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6178187_0	926569.ANT_01410	1.462e-164	526.0	COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
REGS1_k127_6178187_1	926569.ANT_01400	4.211e-158	504.0	COG0444@1|root,COG0444@2|Bacteria,2G5PT@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
REGS1_k127_6178187_2	381764.Fnod_1168	9.119e-44	181.0	COG0747@1|root,COG0747@2|Bacteria,2GC1T@200918|Thermotogae	200918|Thermotogae	E	PFAM extracellular solute-binding protein, family 5	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
REGS1_k127_6178187_4	926569.ANT_31100	2.313e-09	58.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_6181002_2	479434.Sthe_2294	1.077e-111	376.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,2G5ZQ@200795|Chloroflexi,27XZV@189775|Thermomicrobia	189775|Thermomicrobia	C	FAD linked oxidases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_17
REGS1_k127_6181002_1	1121439.dsat_2819	4.245e-115	376.0	COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,42PJM@68525|delta/epsilon subdivisions,2WKJN@28221|Deltaproteobacteria,2M970@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
REGS1_k127_6181002_0	926569.ANT_20730	0.0	1136.0	COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi	200795|Chloroflexi	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
REGS1_k127_6181002_3	1382356.JQMP01000003_gene2108	2.931e-68	247.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
REGS1_k127_6186272_23	926569.ANT_02260	7.86e-34	132.0	COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi	200795|Chloroflexi	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
REGS1_k127_6186272_0	926569.ANT_02250	6.945e-255	797.0	COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
REGS1_k127_6186272_19	926569.ANT_02240	4.897e-40	154.0	COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi	200795|Chloroflexi	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
REGS1_k127_6186272_10	926569.ANT_02230	1.083e-88	304.0	COG0618@1|root,COG0618@2|Bacteria,2G6RF@200795|Chloroflexi	200795|Chloroflexi	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
REGS1_k127_6186272_3	926569.ANT_02220	2.265e-143	459.0	COG0130@1|root,COG0130@2|Bacteria,2G6F4@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
REGS1_k127_6186272_14	926569.ANT_02900	1.355e-75	263.0	COG0196@1|root,COG0196@2|Bacteria,2G6JF@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
REGS1_k127_6186272_2	926569.ANT_02910	8.26e-159	514.0	COG1351@1|root,COG1351@2|Bacteria,2G8EZ@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
REGS1_k127_6186272_4	339670.Bamb_2251	1.002e-140	454.0	COG0667@1|root,COG0667@2|Bacteria,1MU1S@1224|Proteobacteria,2VMYU@28216|Betaproteobacteria,1K2AM@119060|Burkholderiaceae	28216|Betaproteobacteria	C	aldo keto reductase	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
REGS1_k127_6186272_21	926569.ANT_25240	1.544e-35	147.0	COG1388@1|root,COG1388@2|Bacteria,2G9RQ@200795|Chloroflexi	200795|Chloroflexi	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
REGS1_k127_6186272_9	926569.ANT_06790	4.29e-101	336.0	COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
REGS1_k127_6186272_11	926569.ANT_06780	1.323e-85	286.0	COG2229@1|root,COG2229@2|Bacteria,2G8FZ@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
REGS1_k127_6186272_17	1499967.BAYZ01000184_gene4564	8.034e-49	181.0	COG1564@1|root,COG1564@2|Bacteria,2NPUG@2323|unclassified Bacteria	2|Bacteria	H	Thiamin pyrophosphokinase, vitamin B1 binding domain	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
REGS1_k127_6186272_5	926569.ANT_06700	1.093e-136	443.0	COG4143@1|root,COG4143@2|Bacteria,2G615@200795|Chloroflexi	200795|Chloroflexi	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02064	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	SBP_bac_6
REGS1_k127_6186272_1	926569.ANT_06710	4.485e-173	561.0	COG1178@1|root,COG1178@2|Bacteria,2G63A@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02063	ko02010,map02010	M00191	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.19	-	-	BPD_transp_1
REGS1_k127_6186272_8	926569.ANT_23590	6.365e-102	342.0	COG3842@1|root,COG3842@2|Bacteria,2G62Z@200795|Chloroflexi	200795|Chloroflexi	P	TOBE domain	-	-	3.6.3.31	ko:K02062,ko:K11072	ko02010,map02010	M00191,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1,3.A.1.19	-	-	ABC_tran,TOBE_2
REGS1_k127_6186272_22	926569.ANT_23580	1.313e-34	137.0	COG3557@1|root,COG3557@2|Bacteria,2G79G@200795|Chloroflexi	200795|Chloroflexi	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
REGS1_k127_6186272_16	926569.ANT_23560	5.946e-56	201.0	2DM5T@1|root,31U0Y@2|Bacteria,2G78W@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF4126)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4126
REGS1_k127_6186272_18	926569.ANT_23520	1.638e-46	179.0	2E3IJ@1|root,32YH0@2|Bacteria,2G7AM@200795|Chloroflexi	200795|Chloroflexi	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
REGS1_k127_6186272_13	926569.ANT_18930	1.885e-77	278.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	ftsZ	-	-	ko:K03531,ko:K03832	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko02048,ko03036,ko04812	2.C.1.1	-	-	DUF3747,DUF4173,FtsK_4TM,HAMP,HATPase_c,HisKA,TonB_C
REGS1_k127_6186272_7	926569.ANT_02890	4.238e-102	337.0	COG1738@1|root,COG1738@2|Bacteria,2G6BZ@200795|Chloroflexi	200795|Chloroflexi	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
REGS1_k127_6186272_15	765420.OSCT_1893	3.889e-57	211.0	COG0697@1|root,COG0697@2|Bacteria,2G9RG@200795|Chloroflexi,377CV@32061|Chloroflexia	32061|Chloroflexia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_6186272_6	867903.ThesuDRAFT_01142	1.764e-121	415.0	COG1139@1|root,COG1556@1|root,COG1139@2|Bacteria,COG1556@2|Bacteria,1TREQ@1239|Firmicutes,24BXS@186801|Clostridia	186801|Clostridia	C	Iron-sulfur cluster-binding protein	-	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
REGS1_k127_6186272_12	525897.Dbac_1216	7.122e-78	271.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PNX@68525|delta/epsilon subdivisions,2WK8F@28221|Deltaproteobacteria,2M8X5@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cysteine-rich domain	-	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
REGS1_k127_6186272_20	926569.ANT_05040	2.323e-39	152.0	COG0058@1|root,COG0058@2|Bacteria,2G5KG@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
REGS1_k127_6195300_2	747365.Thena_0402	4.982e-23	114.0	COG1215@1|root,COG1215@2|Bacteria,1UI5W@1239|Firmicutes,25EJ5@186801|Clostridia,42JFV@68295|Thermoanaerobacterales	186801|Clostridia	M	COGs COG0463 Glycosyltransferase involved in cell wall biogenesis	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
REGS1_k127_6195300_0	1122939.ATUD01000006_gene1677	8.034e-86	302.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4CPM5@84995|Rubrobacteria	84995|Rubrobacteria	M	UDP binding domain	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
REGS1_k127_6195300_1	1283299.AUKG01000001_gene2252	3.049e-28	119.0	COG0451@1|root,COG0451@2|Bacteria,2GP0W@201174|Actinobacteria,4CPIC@84995|Rubrobacteria	84995|Rubrobacteria	M	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_6208715_4	926569.ANT_21060	2.477e-28	115.0	COG1058@1|root,COG1058@2|Bacteria,2G6DU@200795|Chloroflexi	200795|Chloroflexi	S	PFAM molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CinA,MoCF_biosynth
REGS1_k127_6208715_5	309801.trd_0889	1.334e-17	87.0	COG0665@1|root,COG0665@2|Bacteria,2G6HT@200795|Chloroflexi,27YWR@189775|Thermomicrobia	189775|Thermomicrobia	E	NAD(P)-binding Rossmann-like domain	-	-	1.5.3.1	ko:K00303	ko00260,ko01100,map00260,map01100	-	R00610	RC00060,RC00557	ko00000,ko00001,ko01000	-	-	-	DAO
REGS1_k127_6208715_2	525904.Tter_0589	1.333e-91	306.0	COG0410@1|root,COG0410@2|Bacteria,2NNXF@2323|unclassified Bacteria	2|Bacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
REGS1_k127_6208715_0	926550.CLDAP_29810	3.026e-101	336.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi	200795|Chloroflexi	E	PFAM ABC transporter related	-	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_6208715_1	309801.trd_A0636	4.293e-95	331.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi,27Z3V@189775|Thermomicrobia	189775|Thermomicrobia	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_6208715_3	926550.CLDAP_29790	9.991e-54	192.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_6214523_1	324925.Ppha_1183	8.363e-57	207.0	COG1914@1|root,COG1914@2|Bacteria	2|Bacteria	P	metal ion transmembrane transporter activity	mntH	-	-	-	-	-	-	-	-	-	-	-	Nramp
REGS1_k127_6214523_2	69042.WH5701_08719	7.66e-54	198.0	COG3335@1|root,COG3335@2|Bacteria,1G60T@1117|Cyanobacteria,1H3RV@1129|Synechococcus	1117|Cyanobacteria	L	COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23
REGS1_k127_6214523_0	644966.Tmar_1443	6.522e-70	247.0	COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,24GWH@186801|Clostridia	186801|Clostridia	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
REGS1_k127_6214523_4	633131.TR2A62_0542	9.002e-20	95.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria,2TRQF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_32,rve,rve_3
REGS1_k127_6214523_3	247634.GPB2148_14	8.485e-25	104.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1PBHA@1224|Proteobacteria	1224|Proteobacteria	L	Transposase and inactivated derivatives	-	-	2.7.7.49	ko:K00986,ko:K07497	-	-	-	-	ko00000,ko01000	-	-	-	HTH_32,rve,rve_3
REGS1_k127_6216493_2	926569.ANT_28150	7.096e-111	374.0	COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi	200795|Chloroflexi	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	-	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
REGS1_k127_6216493_3	926569.ANT_03890	2.048e-64	235.0	COG0457@1|root,COG0457@2|Bacteria	926569.ANT_03890|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6216493_6	926569.ANT_03880	1.974e-35	140.0	COG5615@1|root,COG5615@2|Bacteria	2|Bacteria	L	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CopD
REGS1_k127_6216493_0	926569.ANT_03860	4.232e-198	629.0	COG0621@1|root,COG0621@2|Bacteria,2G5ZJ@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_6216493_4	926569.ANT_03850	4.972e-53	205.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi	200795|Chloroflexi	T	SMART helix-turn-helix domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
REGS1_k127_6216493_7	926569.ANT_03850	7.19e-14	78.0	COG1426@1|root,COG1426@2|Bacteria,2G773@200795|Chloroflexi	200795|Chloroflexi	T	SMART helix-turn-helix domain protein	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
REGS1_k127_6216493_5	926569.ANT_03840	1.207e-51	191.0	COG0359@1|root,COG0359@2|Bacteria,2G6V2@200795|Chloroflexi	200795|Chloroflexi	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
REGS1_k127_6216493_8	1521187.JPIM01000017_gene340	0.0001799	49.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	ftsB	GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
REGS1_k127_6216493_1	926550.CLDAP_31520	4.851e-115	383.0	COG0019@1|root,COG0019@2|Bacteria,2G5RR@200795|Chloroflexi	200795|Chloroflexi	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
REGS1_k127_6228401_2	926569.ANT_08340	1.774e-166	531.0	COG1894@1|root,COG1894@2|Bacteria,2G5W1@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_6228401_4	926569.ANT_08330	6.552e-61	214.0	COG1905@1|root,COG1905@2|Bacteria,2G70Y@200795|Chloroflexi	200795|Chloroflexi	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
REGS1_k127_6228401_0	926569.ANT_08320	7.578e-196	625.0	COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
REGS1_k127_6228401_5	926569.ANT_08310	4.392e-53	191.0	COG0852@1|root,COG0852@2|Bacteria,2G6WD@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
REGS1_k127_6228401_3	926569.ANT_08300	2.317e-87	289.0	COG0377@1|root,COG0377@2|Bacteria,2G6GB@200795|Chloroflexi	200795|Chloroflexi	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB1	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
REGS1_k127_6228401_1	926569.ANT_09200	4.12e-173	560.0	COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi	200795|Chloroflexi	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_6243181_2	189425.PGRAT_03670	2.155e-98	344.0	COG1807@1|root,COG1807@2|Bacteria,1UZUR@1239|Firmicutes,4HWIA@91061|Bacilli,26T7F@186822|Paenibacillaceae	91061|Bacilli	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_6243181_3	99598.Cal7507_2915	2.136e-72	260.0	COG5542@1|root,COG5542@2|Bacteria,1GDW7@1117|Cyanobacteria,1HIN0@1161|Nostocales	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6243181_4	643473.KB235930_gene1765	9.211e-70	252.0	COG5542@1|root,COG5542@2|Bacteria,1GDW7@1117|Cyanobacteria,1HIN0@1161|Nostocales	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6243181_0	555079.Toce_1364	6.082e-211	678.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,42F3U@68295|Thermoanaerobacterales	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
REGS1_k127_6243181_1	926569.ANT_16690	4.091e-106	359.0	COG0303@1|root,COG0303@2|Bacteria,2G667@200795|Chloroflexi	200795|Chloroflexi	H	MoeA N-terminal region (domain I and II)	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
REGS1_k127_6243181_6	330779.Saci_1138	2.273e-07	58.0	COG4243@1|root,arCOG03749@2157|Archaea,2XRJ5@28889|Crenarchaeota	28889|Crenarchaeota	S	VKc	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
REGS1_k127_6244224_2	713586.KB900536_gene1113	2.689e-17	87.0	2EKTI@1|root,33EH9@2|Bacteria,1PYIF@1224|Proteobacteria,1SHX2@1236|Gammaproteobacteria,1X1YZ@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6244224_1	713586.KB900536_gene1112	4.17e-53	192.0	COG4083@1|root,COG4083@2|Bacteria,1RI8D@1224|Proteobacteria,1S812@1236|Gammaproteobacteria,1X10E@135613|Chromatiales	135613|Chromatiales	S	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
REGS1_k127_6244224_0	472759.Nhal_3648	4.736e-154	514.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,1RPJS@1236|Gammaproteobacteria,1WVZW@135613|Chromatiales	135613|Chromatiales	NU	Type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
REGS1_k127_6302011_0	330214.NIDE0551	1.041e-255	809.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria	2|Bacteria	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_16,TPR_7,TPR_8
REGS1_k127_6302011_1	330214.NIDE0550	2.969e-29	122.0	COG3087@1|root,COG3087@2|Bacteria	2|Bacteria	D	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	-	-	-	-	-	-	-	-	-	-	-	-	DUF928,NYN
REGS1_k127_6319563_27	926569.ANT_01230	1.67e-23	102.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_6319563_13	196162.Noca_1631	4.34e-136	439.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4DV65@85009|Propionibacteriales	201174|Actinobacteria	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_6319563_7	926569.ANT_01250	9.424e-166	531.0	COG0078@1|root,COG0078@2|Bacteria,2G7QE@200795|Chloroflexi	200795|Chloroflexi	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	-	-	2.1.3.9	ko:K09065	ko00220,ko01100,ko01230,map00220,map01100,map01230	M00845	R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_6319563_12	926569.ANT_01260	1.802e-143	461.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi	200795|Chloroflexi	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
REGS1_k127_6319563_4	926569.ANT_04720	1.659e-201	634.0	COG1744@1|root,COG1744@2|Bacteria,2G6CN@200795|Chloroflexi	200795|Chloroflexi	M	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K02058,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Bmp
REGS1_k127_6319563_2	926569.ANT_04710	1.049e-224	708.0	COG3845@1|root,COG3845@2|Bacteria,2G68B@200795|Chloroflexi	200795|Chloroflexi	S	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
REGS1_k127_6319563_8	926569.ANT_04700	1.153e-158	508.0	COG4603@1|root,COG4603@2|Bacteria,2G686@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
REGS1_k127_6319563_5	926569.ANT_04690	1.224e-167	530.0	COG1079@1|root,COG1079@2|Bacteria,2G6CY@200795|Chloroflexi	200795|Chloroflexi	S	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
REGS1_k127_6319563_19	926569.ANT_14800	1.81e-88	300.0	COG1319@1|root,COG1319@2|Bacteria,2G8QC@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
REGS1_k127_6319563_0	926569.ANT_14810	0.0	1206.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2G65D@200795|Chloroflexi	200795|Chloroflexi	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
REGS1_k127_6319563_6	926569.ANT_04670	2.466e-167	535.0	COG0498@1|root,COG0498@2|Bacteria,2G6D6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_6319563_11	926569.ANT_04660	9.787e-146	467.0	COG0463@1|root,COG0463@2|Bacteria,2G5JH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
REGS1_k127_6319563_20	479434.Sthe_2389	1.978e-81	277.0	COG4122@1|root,COG4122@2|Bacteria,2G990@200795|Chloroflexi,27ZCN@189775|Thermomicrobia	189775|Thermomicrobia	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
REGS1_k127_6319563_1	926569.ANT_04650	1.658e-240	751.0	COG0031@1|root,COG0031@2|Bacteria,2G8GE@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
REGS1_k127_6319563_23	926569.ANT_04640	3.682e-59	210.0	COG2852@1|root,COG2852@2|Bacteria,2G78G@200795|Chloroflexi	200795|Chloroflexi	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6319563_16	324602.Caur_0607	1.35e-115	394.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,2G7T5@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
REGS1_k127_6319563_3	926569.ANT_00270	2.363e-213	677.0	COG0044@1|root,COG0044@2|Bacteria,2G5N4@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	3.5.2.2,3.5.2.5	ko:K01464,ko:K01466	ko00230,ko00240,ko00410,ko00770,ko00983,ko01100,ko01120,map00230,map00240,map00410,map00770,map00983,map01100,map01120	M00046,M00546	R02269,R02425,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
REGS1_k127_6319563_24	926569.ANT_30860	7.361e-47	177.0	COG0204@1|root,COG0204@2|Bacteria,2G78P@200795|Chloroflexi	200795|Chloroflexi	I	PFAM phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_6319563_10	926569.ANT_17310	2.976e-150	484.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_6319563_18	316274.Haur_3936	7.43e-105	355.0	COG0477@1|root,COG2223@1|root,COG2223@2|Bacteria,COG2814@2|Bacteria,2GA7I@200795|Chloroflexi,3780K@32061|Chloroflexia	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_6319563_25	926550.CLDAP_07730	2.762e-46	173.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_10010	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_6319563_14	926550.CLDAP_07720	8.419e-121	398.0	COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
REGS1_k127_6319563_15	926550.CLDAP_07700	7.773e-118	387.0	COG1131@1|root,COG1131@2|Bacteria,2G7Q5@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_6319563_17	926550.CLDAP_07690	5.766e-107	356.0	COG1131@1|root,COG1131@2|Bacteria,2G7U7@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_6319563_30	390989.JOEG01000025_gene47	1.55e-12	69.0	COG1983@1|root,COG1983@2|Bacteria,2IRZU@201174|Actinobacteria,4DFHJ@85008|Micromonosporales	201174|Actinobacteria	KT	PspC domain	-	-	-	ko:K03973	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	PspC
REGS1_k127_6319563_26	304371.MCP_0732	3.547e-44	167.0	COG0432@1|root,arCOG04214@2157|Archaea,2XYW0@28890|Euryarchaeota,2N9WB@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
REGS1_k127_6319563_22	1035308.AQYY01000001_gene2006	1.471e-61	220.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,264ZM@186807|Peptococcaceae	186801|Clostridia	S	conserved protein (DUF2174)	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
REGS1_k127_6319563_21	1121406.JAEX01000007_gene2388	1.575e-67	241.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2M80Z@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
REGS1_k127_6323490_5	926569.ANT_30000	1.605e-78	270.0	COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
REGS1_k127_6323490_3	502025.Hoch_3258	2.452e-88	298.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,4385Z@68525|delta/epsilon subdivisions,2X3FT@28221|Deltaproteobacteria,2YVWY@29|Myxococcales	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
REGS1_k127_6323490_7	1089550.ATTH01000001_gene1187	7.962e-29	127.0	COG3339@1|root,COG3339@2|Bacteria,4NRQP@976|Bacteroidetes,1FK9F@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
REGS1_k127_6323490_6	926569.ANT_27110	4.534e-63	225.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6323490_0	1128421.JAGA01000002_gene1310	5.709e-153	493.0	COG0436@1|root,COG0436@2|Bacteria,2NP1C@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase	yugH	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_6323490_2	926569.ANT_03150	1.052e-110	367.0	COG1208@1|root,COG1208@2|Bacteria,2G5KH@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Nucleotidyl transferase	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
REGS1_k127_6323490_8	1282876.BAOK01000001_gene1190	6.625e-26	113.0	COG1051@1|root,COG1051@2|Bacteria,1N0YW@1224|Proteobacteria,2UC2E@28211|Alphaproteobacteria,4BSK1@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_6323490_1	1267535.KB906767_gene4461	4.582e-147	471.0	COG0667@1|root,COG0667@2|Bacteria,3Y35T@57723|Acidobacteria,2JK73@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_6323490_4	926569.ANT_25570	5.78e-82	279.0	COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi	200795|Chloroflexi	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_6372450_1	926569.ANT_21000	2.847e-47	174.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
REGS1_k127_6372450_0	926569.ANT_11400	6.61e-96	329.0	COG0768@1|root,COG0772@1|root,COG0768@2|Bacteria,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi	200795|Chloroflexi	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
REGS1_k127_6379699_10	315730.BcerKBAB4_3882	8.596e-06	49.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus	91061|Bacilli	K	transcriptional	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_6379699_1	525904.Tter_0202	4.716e-82	287.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
REGS1_k127_6379699_8	797209.ZOD2009_18884	7.423e-21	96.0	COG4392@1|root,arCOG06625@2157|Archaea,2XZ4G@28890|Euryarchaeota,23WTM@183963|Halobacteria	183963|Halobacteria	S	Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
REGS1_k127_6379699_5	485913.Krac_5262	1.717e-56	211.0	COG1296@1|root,COG1296@2|Bacteria,2G6SG@200795|Chloroflexi	200795|Chloroflexi	E	PFAM AzlC family protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
REGS1_k127_6379699_2	525904.Tter_0202	3.488e-79	274.0	COG2141@1|root,COG2141@2|Bacteria	2|Bacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
REGS1_k127_6379699_4	515635.Dtur_0647	2.266e-58	212.0	COG0800@1|root,COG0800@2|Bacteria	2|Bacteria	G	2-dehydro-3-deoxy-phosphogluconate aldolase activity	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
REGS1_k127_6379699_11	1122611.KB903952_gene5924	0.0002281	47.0	COG2329@1|root,COG2329@2|Bacteria,2GQ3W@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
REGS1_k127_6379699_7	1408254.T458_27215	2.711e-49	185.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,275EV@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
REGS1_k127_6379699_6	411684.HPDFL43_02000	1.251e-55	203.0	COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TUCX@28211|Alphaproteobacteria,43JDI@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
REGS1_k127_6379699_3	639030.JHVA01000001_gene115	3.916e-65	237.0	COG0006@1|root,COG0006@2|Bacteria,3Y3IN@57723|Acidobacteria,2JI8R@204432|Acidobacteriia	2|Bacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.5.3.3	ko:K08688	ko00260,ko00330,ko01100,map00260,map00330,map01100	-	R01566	RC00548,RC00549	ko00000,ko00001,ko01000	-	-	-	Creatinase_N,Peptidase_M24
REGS1_k127_6379699_0	1174528.JH992893_gene5998	4.367e-109	359.0	COG1028@1|root,COG1028@2|Bacteria,1G2YY@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
REGS1_k127_6379699_9	1124780.ANNU01000008_gene2694	5.349e-07	58.0	COG0524@1|root,COG0524@2|Bacteria,4NFH8@976|Bacteroidetes,47KKJ@768503|Cytophagia	976|Bacteroidetes	G	PFAM PfkB	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
REGS1_k127_641313_1	269797.Mbar_A2478	1.378e-27	126.0	COG1073@1|root,arCOG01661@2157|Archaea,2XVIC@28890|Euryarchaeota,2NANZ@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S9
REGS1_k127_641313_2	63737.Npun_R6524	1.322e-16	80.0	COG1100@1|root,COG4886@1|root,COG1100@2|Bacteria,COG4886@2|Bacteria,1G05B@1117|Cyanobacteria,1HK2M@1161|Nostocales	1117|Cyanobacteria	S	C-terminal of Roc, COR, domain	-	-	-	-	-	-	-	-	-	-	-	-	COR,LRR_4,LRR_8,Roc
REGS1_k127_641313_0	404589.Anae109_2186	1.225e-221	693.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_6426148_3	401526.TcarDRAFT_2729	4.891e-06	55.0	COG3464@1|root,COG3464@2|Bacteria,1VFE7@1239|Firmicutes	1239|Firmicutes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6426148_1	1089550.ATTH01000001_gene2411	2.195e-34	145.0	COG0358@1|root,COG0358@2|Bacteria,4NENT@976|Bacteroidetes,1FJ4P@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
REGS1_k127_6426148_0	1229780.BN381_600013	3.012e-43	171.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_6426148_2	350058.Mvan_1114	5.538e-34	143.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria,236NP@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
REGS1_k127_6441004_7	358220.C380_13035	2.197e-12	78.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2VHTM@28216|Betaproteobacteria,4AC1V@80864|Comamonadaceae	28216|Betaproteobacteria	G	SMP-30 Gluconolaconase	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
REGS1_k127_6441004_3	1157490.EL26_15890	1.531e-48	180.0	COG1051@1|root,COG1051@2|Bacteria,1V6D5@1239|Firmicutes,4HJTU@91061|Bacilli	91061|Bacilli	F	Nudix hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_6441004_2	765869.BDW_12865	2.402e-59	218.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2MTST@213481|Bdellovibrionales,2WQCC@28221|Deltaproteobacteria	213481|Bdellovibrionales	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
REGS1_k127_6441004_4	1140.Synpcc7942_0124	2.551e-42	164.0	COG0500@1|root,COG0500@2|Bacteria,1G56P@1117|Cyanobacteria,1H0ID@1129|Synechococcus	1117|Cyanobacteria	Q	Thiopurine S-methyltransferase (TPMT)	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	TPMT
REGS1_k127_6441004_1	926560.KE387023_gene1407	3.698e-61	228.0	COG1030@1|root,COG1030@2|Bacteria,1WKAY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6441004_6	1210908.HSB1_33070	3.675e-17	93.0	arCOG09492@1|root,arCOG09492@2157|Archaea,2Y1Y1@28890|Euryarchaeota	28890|Euryarchaeota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6441004_5	317936.Nos7107_3521	4.675e-30	124.0	2BK9M@1|root,32EPT@2|Bacteria,1G703@1117|Cyanobacteria,1HS5Z@1161|Nostocales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6441004_0	926569.ANT_11970	2.935e-116	382.0	COG1148@1|root,COG1148@2|Bacteria,2G7GY@200795|Chloroflexi	200795|Chloroflexi	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6455546_8	247634.GPB2148_963	2.364e-36	156.0	2AMTK@1|root,31CQ4@2|Bacteria,1P2SV@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6455546_7	1382306.JNIM01000001_gene758	1.375e-38	156.0	COG0697@1|root,COG0697@2|Bacteria,2G8R9@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_6455546_6	304371.MCP_1048	2.729e-46	176.0	COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,2N96I@224756|Methanomicrobia	224756|Methanomicrobia	H	PFAM bifunctional deaminase-reductase domain protein	-	-	1.1.1.302	ko:K14654	ko00740,ko01100,map00740,map01100	-	R09375,R09376	RC00933	ko00000,ko00001,ko01000	-	-	-	RibD_C
REGS1_k127_6455546_5	1121272.KB903259_gene6573	8.823e-53	197.0	COG0726@1|root,COG0726@2|Bacteria,2I132@201174|Actinobacteria,4DHHE@85008|Micromonosporales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_6455546_3	926569.ANT_26640	8.46e-72	252.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
REGS1_k127_6455546_1	926569.ANT_26640	2.629e-99	342.0	COG0308@1|root,COG0308@2|Bacteria,2G75V@200795|Chloroflexi	200795|Chloroflexi	E	PFAM peptidase M1, membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
REGS1_k127_6455546_11	1218108.KB908292_gene1642	2.759e-06	55.0	COG1670@1|root,COG1670@2|Bacteria,4NRSJ@976|Bacteroidetes,1IJDN@117743|Flavobacteriia	976|Bacteroidetes	J	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
REGS1_k127_6455546_0	357808.RoseRS_1256	1.016e-101	339.0	COG1108@1|root,COG1108@2|Bacteria,2G6GH@200795|Chloroflexi,376AB@32061|Chloroflexia	32061|Chloroflexia	P	ABC-3 protein	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
REGS1_k127_6455546_2	383372.Rcas_1590	1.46e-94	316.0	COG1121@1|root,COG1121@2|Bacteria,2G7X2@200795|Chloroflexi,377ZC@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
REGS1_k127_6455546_4	1128421.JAGA01000003_gene3096	4.41e-68	244.0	COG0803@1|root,COG0803@2|Bacteria,2NP5U@2323|unclassified Bacteria	2|Bacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077,ko:K09818	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
REGS1_k127_6455546_9	877455.Metbo_1631	2.128e-23	101.0	COG1917@1|root,arCOG02994@2157|Archaea	2157|Archaea	JM	conserved protein, contains double-stranded beta-helix domain	-	-	1.13.11.4,4.2.1.108	ko:K00450,ko:K06720	ko00260,ko00350,ko01100,ko01120,map00260,map00350,map01100,map01120	M00033	R02656,R06979	RC00764,RC01729	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,Ectoine_synth
REGS1_k127_648757_2	926569.ANT_25700	2.551e-28	121.0	COG0265@1|root,COG0642@1|root,COG2203@1|root,COG0265@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,2G7SE@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
REGS1_k127_648757_3	765420.OSCT_1064	4.362e-06	57.0	COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia	32061|Chloroflexia	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
REGS1_k127_648757_0	926569.ANT_30670	2.061e-293	911.0	COG0443@1|root,COG0443@2|Bacteria,2G5U5@200795|Chloroflexi	200795|Chloroflexi	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
REGS1_k127_648757_1	926569.ANT_23190	1.868e-114	383.0	COG0457@1|root,COG0457@2|Bacteria,2G8PU@200795|Chloroflexi	200795|Chloroflexi	S	Peptidase_C39 like family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
REGS1_k127_6532148_0	886293.Sinac_1249	0.0	1262.0	COG3459@1|root,COG3459@2|Bacteria,2IYJ0@203682|Planctomycetes	203682|Planctomycetes	G	Putative glucoamylase	-	-	-	ko:K13688	-	-	-	-	ko00000,ko01000,ko01003	-	GH94,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_6532148_12	1111728.ATYS01000025_gene4243	3.559e-21	104.0	2DC1F@1|root,2ZCE5@2|Bacteria,1RCQ9@1224|Proteobacteria,1S28C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
REGS1_k127_6532148_13	748727.CLJU_c23620	1.312e-17	88.0	COG1545@1|root,COG1545@2|Bacteria	2|Bacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	phlB	-	-	ko:K07068,ko:K07549	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05587	RC00004,RC01428,RC02904	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF35_N,OB_aCoA_assoc
REGS1_k127_6532148_7	748727.CLJU_c23630	2.57e-137	447.0	COG0183@1|root,COG0183@2|Bacteria,1TT8U@1239|Firmicutes,24FFI@186801|Clostridia	186801|Clostridia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_6532148_10	748727.CLJU_c23640	5.457e-69	241.0	2ATRB@1|root,31JA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6532148_5	926569.ANT_05840	2.117e-165	522.0	COG1878@1|root,COG1878@2|Bacteria,2G8DE@200795|Chloroflexi	200795|Chloroflexi	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
REGS1_k127_6532148_1	926569.ANT_05790	0.0	1104.0	COG1529@1|root,COG1529@2|Bacteria,2G7M5@200795|Chloroflexi	200795|Chloroflexi	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
REGS1_k127_6532148_11	926569.ANT_05780	6.192e-68	235.0	COG2080@1|root,COG2080@2|Bacteria,2G6NT@200795|Chloroflexi	200795|Chloroflexi	C	2Fe-2S -binding domain protein	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
REGS1_k127_6532148_9	926569.ANT_05770	5.164e-111	366.0	COG1319@1|root,COG1319@2|Bacteria,2G8QI@200795|Chloroflexi	200795|Chloroflexi	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
REGS1_k127_6532148_6	479434.Sthe_3301	4.813e-153	493.0	COG1804@1|root,COG1804@2|Bacteria,2G7MX@200795|Chloroflexi,27YZQ@189775|Thermomicrobia	189775|Thermomicrobia	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
REGS1_k127_6532148_8	350688.Clos_0875	1.427e-113	375.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,36KEG@31979|Clostridiaceae	186801|Clostridia	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
REGS1_k127_6532148_3	926569.ANT_05660	1.087e-223	707.0	COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi	200795|Chloroflexi	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
REGS1_k127_6532148_4	926569.ANT_05670	9.738e-207	649.0	COG0074@1|root,COG0074@2|Bacteria,2G7UI@200795|Chloroflexi	200795|Chloroflexi	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
REGS1_k127_6532148_2	926569.ANT_05680	3.955e-294	906.0	COG1878@1|root,COG1878@2|Bacteria,2G8DE@200795|Chloroflexi	2|Bacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
REGS1_k127_6540121_2	383372.Rcas_2403	6.212e-78	263.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	pfpI	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
REGS1_k127_6540121_0	498761.HM1_2746	2.549e-98	332.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia	186801|Clostridia	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
REGS1_k127_6540121_1	498761.HM1_2746	1.468e-87	298.0	COG0306@1|root,COG0306@2|Bacteria,1TQ3D@1239|Firmicutes,247ZC@186801|Clostridia	186801|Clostridia	P	phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
REGS1_k127_6546781_1	926569.ANT_30340	1.699e-106	349.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2G5J0@200795|Chloroflexi	200795|Chloroflexi	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
REGS1_k127_6546781_0	926569.ANT_30330	1.679e-191	623.0	COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi	200795|Chloroflexi	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
REGS1_k127_65481_1	926569.ANT_30160	1.724e-148	475.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_65481_2	926569.ANT_25670	2.135e-135	451.0	2EDFC@1|root,3366P@2|Bacteria,2G7IW@200795|Chloroflexi	200795|Chloroflexi	S	Helicase conserved C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C_3
REGS1_k127_65481_3	926569.ANT_25680	2.754e-96	324.0	COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi	200795|Chloroflexi	I	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
REGS1_k127_65481_0	1265505.ATUG01000001_gene3075	2.198e-154	497.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MKR@68525|delta/epsilon subdivisions,2WIS3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_65481_5	1321778.HMPREF1982_02159	2.339e-28	123.0	COG0500@1|root,COG2226@2|Bacteria,1V3T6@1239|Firmicutes,24GHB@186801|Clostridia,26AWP@186813|unclassified Clostridiales	186801|Clostridia	Q	AdoMet dependent proline di-methyltransferase	smtA	-	-	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00609	R10404	RC00003	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
REGS1_k127_65481_4	926569.ANT_30560	1.98e-57	204.0	COG0215@1|root,COG0215@2|Bacteria,2G5Z0@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
REGS1_k127_6553353_1	926550.CLDAP_22060	2.956e-83	290.0	COG0438@1|root,COG0438@2|Bacteria,2G8P6@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_6553353_2	926550.CLDAP_37480	6.82e-31	130.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	yohD	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944	3.6.1.27,4.1.3.25	ko:K03975,ko:K18292,ko:K19302	ko00550,ko00660,ko01100,map00550,map00660,map01100	-	R00237,R05627	RC00002,RC00502,RC01205	ko00000,ko00001,ko01000,ko01011	-	-	-	Rhodanese,SNARE_assoc
REGS1_k127_6553353_0	926550.CLDAP_11260	2.349e-88	295.0	COG1132@1|root,COG1132@2|Bacteria,2G7QN@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
REGS1_k127_6555320_3	511051.CSE_07130	2.899e-10	61.0	2ATRB@1|root,31JA4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6555320_0	926569.ANT_05660	2.04e-212	675.0	COG0074@1|root,COG0074@2|Bacteria,2G7NQ@200795|Chloroflexi	200795|Chloroflexi	C	CoA-ligase	-	-	-	ko:K02381	-	-	-	-	ko00000	-	-	-	CoA_binding,Ligase_CoA
REGS1_k127_6555320_4	566466.NOR53_2755	6.96e-08	59.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Integrase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
REGS1_k127_6555320_1	926569.ANT_05670	8.595e-208	651.0	COG0074@1|root,COG0074@2|Bacteria,2G7UI@200795|Chloroflexi	200795|Chloroflexi	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1116
REGS1_k127_6555320_2	926569.ANT_05680	4.694e-40	150.0	COG1878@1|root,COG1878@2|Bacteria,2G8DE@200795|Chloroflexi	2|Bacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
REGS1_k127_659459_0	926550.CLDAP_22400	9.963e-224	700.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	iECABU_c1320.ECABU_c30720,ic_1306.c3371	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
REGS1_k127_659459_6	697281.Mahau_2055	1.766e-36	149.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,42GT1@68295|Thermoanaerobacterales	186801|Clostridia	K	transcriptional regulator (GntR	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_659459_5	309801.trd_1316	1.073e-43	179.0	COG0531@1|root,COG0531@2|Bacteria,2G76Z@200795|Chloroflexi	200795|Chloroflexi	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_659459_3	1382306.JNIM01000001_gene2131	1.839e-75	265.0	COG2129@1|root,COG2129@2|Bacteria,2G7X0@200795|Chloroflexi	200795|Chloroflexi	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_659459_4	1128421.JAGA01000003_gene3663	4.623e-46	176.0	arCOG06048@1|root,31EJQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_659459_2	1499967.BAYZ01000117_gene3321	3.928e-79	277.0	COG0079@1|root,COG0079@2|Bacteria,2NNZK@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	hisD	-	1.1.1.23,2.6.1.9	ko:K00013,ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03243	RC00006,RC00099,RC00242,RC00463,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,Histidinol_dh
REGS1_k127_659459_1	1304866.K413DRAFT_1467	2.204e-106	363.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,36F3K@31979|Clostridiaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
REGS1_k127_659459_7	479434.Sthe_0660	7.238e-13	78.0	2EHA5@1|root,33B21@2|Bacteria,2G7H6@200795|Chloroflexi,27YSP@189775|Thermomicrobia	189775|Thermomicrobia	S	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
REGS1_k127_6637070_3	1243664.CAVL020000032_gene2745	7.168e-06	48.0	COG0454@1|root,COG0456@2|Bacteria,1V9FV@1239|Firmicutes,4HNZV@91061|Bacilli,1ZGNN@1386|Bacillus	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_6637070_0	926569.ANT_01730	1.402e-164	528.0	COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi	200795|Chloroflexi	M	PFAM glycosyl transferase group 1	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_6637070_2	926569.ANT_26870	3.971e-89	300.0	COG1432@1|root,COG1432@2|Bacteria,2G7FS@200795|Chloroflexi	200795|Chloroflexi	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
REGS1_k127_6637070_1	526227.Mesil_2412	1.645e-151	491.0	COG0665@1|root,COG0665@2|Bacteria,1WI96@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
REGS1_k127_6700703_2	926569.ANT_21050	5.169e-75	258.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
REGS1_k127_6700703_1	926569.ANT_22320	3.312e-95	323.0	COG1559@1|root,COG1559@2|Bacteria,2G6G8@200795|Chloroflexi	200795|Chloroflexi	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
REGS1_k127_6700703_4	926569.ANT_22310	7.475e-31	127.0	COG0816@1|root,COG0816@2|Bacteria,2G74F@200795|Chloroflexi	200795|Chloroflexi	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
REGS1_k127_6700703_3	926569.ANT_22300	1.11e-69	255.0	COG3299@1|root,COG3299@2|Bacteria	2|Bacteria	S	Baseplate J-like protein	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Baseplate_J,PA14,fn3
REGS1_k127_6700703_0	926569.ANT_16840	0.0	1110.0	COG0013@1|root,COG0013@2|Bacteria,2G5KW@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
REGS1_k127_6710920_10	926569.ANT_29550	1.482e-61	220.0	COG0631@1|root,COG0631@2|Bacteria,2G6R4@200795|Chloroflexi	200795|Chloroflexi	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
REGS1_k127_6710920_6	926569.ANT_29560	1.903e-91	326.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	CP_0034	-	-	-	-	-	-	-	-	-	-	-	BON,FHA,FTSW_RODA_SPOVE,Yop-YscD_cpl
REGS1_k127_6710920_12	926569.ANT_25500	1.345e-51	195.0	2DFV5@1|root,2ZT9W@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6710920_2	557598.LHK_00777	1.877e-174	561.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,2KPJ8@206351|Neisseriales	206351|Neisseriales	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
REGS1_k127_6710920_9	926569.ANT_25520	1.02e-77	265.0	COG0503@1|root,COG0503@2|Bacteria,2G71F@200795|Chloroflexi	200795|Chloroflexi	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
REGS1_k127_6710920_11	926569.ANT_02780	5.924e-59	214.0	COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi	200795|Chloroflexi	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
REGS1_k127_6710920_0	926569.ANT_02790	1.939e-203	659.0	COG0768@1|root,COG0768@2|Bacteria,2G7WI@200795|Chloroflexi	200795|Chloroflexi	M	NTF2-like N-terminal transpeptidase domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
REGS1_k127_6710920_3	926569.ANT_02800	9.278e-111	365.0	COG1162@1|root,COG1162@2|Bacteria,2G5IS@200795|Chloroflexi	200795|Chloroflexi	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
REGS1_k127_6710920_5	926569.ANT_02540	2.968e-103	345.0	COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
REGS1_k127_6710920_13	35754.JNYJ01000011_gene809	1.692e-13	72.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria,4DEUQ@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
REGS1_k127_6710920_7	926569.ANT_07470	2.005e-87	296.0	COG1116@1|root,COG1116@2|Bacteria,2G8C7@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
REGS1_k127_6710920_4	926569.ANT_07480	1.096e-110	366.0	COG0715@1|root,COG0715@2|Bacteria,2G6E9@200795|Chloroflexi	200795|Chloroflexi	P	PFAM NMT1 THI5 like domain protein	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
REGS1_k127_6710920_8	926569.ANT_07490	4.594e-83	286.0	COG0600@1|root,COG0600@2|Bacteria,2G6HW@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
REGS1_k127_6710920_1	926569.ANT_18040	2.209e-186	591.0	COG0156@1|root,COG0156@2|Bacteria,2G65Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_6710920_14	102232.GLO73106DRAFT_00012770	1.542e-09	61.0	COG1028@1|root,COG1028@2|Bacteria,1G3UI@1117|Cyanobacteria	1117|Cyanobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.102	ko:K04708	ko00600,ko01100,map00600,map01100	M00094,M00099	R02978	RC00089	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short
REGS1_k127_6711834_2	926550.CLDAP_31600	2.118e-76	265.0	COG1063@1|root,COG1063@2|Bacteria,2G6FN@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
REGS1_k127_6711834_3	1089550.ATTH01000001_gene798	1.488e-74	257.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,4PIWG@976|Bacteroidetes,1FK0G@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydro2,RibD_C
REGS1_k127_6711834_7	926550.CLDAP_07570	1.664e-41	168.0	COG0392@1|root,COG0392@2|Bacteria,2G96G@200795|Chloroflexi	200795|Chloroflexi	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
REGS1_k127_6711834_6	1123504.JQKD01000008_gene5341	1.676e-45	175.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
REGS1_k127_6711834_9	357808.RoseRS_2245	9.518e-19	90.0	COG2127@1|root,COG2127@2|Bacteria,2G9F8@200795|Chloroflexi,375WT@32061|Chloroflexia	32061|Chloroflexia	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
REGS1_k127_6711834_5	1231241.Mc24_02863	1.519e-67	239.0	COG0656@1|root,COG0656@2|Bacteria,2GCHS@200918|Thermotogae	200918|Thermotogae	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_6711834_4	926569.ANT_04520	5.151e-70	242.0	COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porG	-	1.2.7.1,1.2.7.3	ko:K00172,ko:K00177	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00307,M00374,M00620	R01196,R01197,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
REGS1_k127_6711834_1	926569.ANT_04510	2.553e-130	420.0	COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi	200795|Chloroflexi	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
REGS1_k127_6711834_0	926569.ANT_04500	2.13e-169	539.0	COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi	200795|Chloroflexi	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
REGS1_k127_6711834_8	926569.ANT_04490	3.4e-28	115.0	COG1146@1|root,COG1146@2|Bacteria,2G7ES@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
REGS1_k127_6712602_1	1380394.JADL01000007_gene4482	2.503e-127	415.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria,2JRDX@204441|Rhodospirillales	204441|Rhodospirillales	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
REGS1_k127_6712602_2	1207063.P24_03930	9.588e-115	375.0	COG1028@1|root,COG1028@2|Bacteria,1MUFX@1224|Proteobacteria,2TRWN@28211|Alphaproteobacteria,2JRJC@204441|Rhodospirillales	204441|Rhodospirillales	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
REGS1_k127_6712602_0	234267.Acid_6581	3.654e-203	638.0	COG0183@1|root,COG0183@2|Bacteria,3Y7RP@57723|Acidobacteria	57723|Acidobacteria	I	Thiolase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_6712602_6	292.DM42_4392	0.0008835	45.0	COG2267@1|root,COG2267@2|Bacteria,1MW9H@1224|Proteobacteria,2VMHB@28216|Betaproteobacteria,1K32Y@119060|Burkholderiaceae	28216|Betaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
REGS1_k127_6712602_4	1005048.CFU_0218	5.061e-08	55.0	COG2267@1|root,COG2267@2|Bacteria,1REM6@1224|Proteobacteria,2VPYQ@28216|Betaproteobacteria,4758X@75682|Oxalobacteraceae	28216|Betaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
REGS1_k127_6712602_5	1279009.ADICEAN_01090	0.0002039	47.0	COG2267@1|root,COG2267@2|Bacteria,4NF80@976|Bacteroidetes,47KEX@768503|Cytophagia	976|Bacteroidetes	I	alpha/beta hydrolase fold	pcbD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
REGS1_k127_6712602_3	1173026.Glo7428_3910	2.118e-09	62.0	COG2267@1|root,COG2267@2|Bacteria,1G4F2@1117|Cyanobacteria	1117|Cyanobacteria	I	COGs COG0596 hydrolase or acyltransferase (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
REGS1_k127_671262_6	765420.OSCT_1126	3.99e-17	85.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
REGS1_k127_671262_2	926569.ANT_02020	1.648e-148	475.0	COG1788@1|root,COG1788@2|Bacteria,2G6IM@200795|Chloroflexi	200795|Chloroflexi	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
REGS1_k127_671262_0	926569.ANT_02040	3.136e-240	756.0	COG1012@1|root,COG1012@2|Bacteria,2G61H@200795|Chloroflexi	200795|Chloroflexi	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
REGS1_k127_671262_3	926569.ANT_15610	1.374e-77	269.0	COG1912@1|root,COG1912@2|Bacteria,2G6NI@200795|Chloroflexi	200795|Chloroflexi	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
REGS1_k127_671262_1	926569.ANT_15620	7.87e-189	604.0	COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
REGS1_k127_671262_5	926569.ANT_15630	5.381e-30	131.0	COG4720@1|root,COG4720@2|Bacteria,2G91D@200795|Chloroflexi	200795|Chloroflexi	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16924	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.29	-	-	ECF-ribofla_trS
REGS1_k127_671262_4	926569.ANT_15640	3.499e-61	227.0	COG0619@1|root,COG0619@2|Bacteria,2G8RH@200795|Chloroflexi	200795|Chloroflexi	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
REGS1_k127_6718231_10	1173028.ANKO01000038_gene4765	1.293e-14	77.0	2E4G4@1|root,32ZB9@2|Bacteria,1G9UK@1117|Cyanobacteria,1HD1D@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6718231_1	63737.Npun_F5602	2.076e-130	428.0	COG3227@1|root,COG3227@2|Bacteria,1G3KW@1117|Cyanobacteria,1HMHN@1161|Nostocales	1117|Cyanobacteria	E	PFAM Thermolysin metallopeptidase, alpha-helical domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,Peptidase_M4,Peptidase_M4_C
REGS1_k127_6718231_3	926569.ANT_04560	2.133e-99	331.0	COG0796@1|root,COG0796@2|Bacteria,2G8GN@200795|Chloroflexi	200795|Chloroflexi	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
REGS1_k127_6718231_6	926569.ANT_04550	5.465e-63	224.0	COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi	200795|Chloroflexi	S	PFAM glutamine amidotransferase class-I	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
REGS1_k127_6718231_9	926569.ANT_04540	6.661e-38	145.0	COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi	200795|Chloroflexi	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
REGS1_k127_6718231_2	485916.Dtox_1182	7.409e-129	424.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,2602N@186807|Peptococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_6718231_5	641491.DND132_1124	1.253e-65	237.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WPYW@28221|Deltaproteobacteria,2MC7X@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_6718231_4	926569.ANT_22470	7.236e-66	227.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi	200795|Chloroflexi	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
REGS1_k127_6718231_12	756272.Plabr_3958	2.035e-12	70.0	COG1977@1|root,COG1977@2|Bacteria,2J18K@203682|Planctomycetes	203682|Planctomycetes	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_6718231_8	926569.ANT_22480	5.171e-59	209.0	COG0315@1|root,COG0315@2|Bacteria,2G6PC@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
REGS1_k127_6718231_7	926569.ANT_22490	2.653e-59	221.0	COG1354@1|root,COG1354@2|Bacteria,2G6WU@200795|Chloroflexi	200795|Chloroflexi	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
REGS1_k127_6718231_11	986075.CathTA2_2041	2.078e-14	80.0	COG5652@1|root,COG5652@2|Bacteria,1VGDJ@1239|Firmicutes,4HNZ0@91061|Bacilli	91061|Bacilli	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
REGS1_k127_6718231_14	1173025.GEI7407_3330	0.0001806	52.0	COG0515@1|root,COG0515@2|Bacteria,1G0HV@1117|Cyanobacteria,1H80G@1150|Oscillatoriales	1117|Cyanobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_6718231_0	926569.ANT_11410	6.009e-217	694.0	COG1331@1|root,COG1331@2|Bacteria,2G5R1@200795|Chloroflexi	200795|Chloroflexi	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
REGS1_k127_6728400_0	234267.Acid_6681	1.465e-245	764.0	COG1271@1|root,COG1271@2|Bacteria,3Y44V@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
REGS1_k127_6728400_1	234267.Acid_6682	1.66e-170	540.0	COG1294@1|root,COG1294@2|Bacteria,3Y3UT@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome d ubiquinol oxidase, subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
REGS1_k127_6750545_1	251221.35211789	4.033e-24	103.0	COG0115@1|root,COG0115@2|Bacteria,1G1GM@1117|Cyanobacteria	1117|Cyanobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
REGS1_k127_6750545_0	1403819.BATR01000022_gene806	1.548e-184	608.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
REGS1_k127_678495_0	251221.35211202	2.316e-99	338.0	COG3119@1|root,COG3119@2|Bacteria,1G5IZ@1117|Cyanobacteria	1117|Cyanobacteria	P	Arylsulfatase a	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	DUF4976,Sulfatase,Sulfatase_C
REGS1_k127_680318_1	926569.ANT_03170	7.351e-118	385.0	COG0154@1|root,COG0154@2|Bacteria,2G5T0@200795|Chloroflexi	200795|Chloroflexi	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
REGS1_k127_680318_11	926550.CLDAP_12350	4.016e-05	55.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	3.4.21.107,3.5.1.28	ko:K01448,ko:K04771	ko01503,ko02020,map01503,map02020	M00727,M00728	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko03036,ko03110	-	-	-	SH3_3
REGS1_k127_680318_3	765420.OSCT_1396	3.513e-114	377.0	COG1087@1|root,COG1087@2|Bacteria,2G5QM@200795|Chloroflexi,3754S@32061|Chloroflexia	32061|Chloroflexia	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_680318_4	1173027.Mic7113_0692	1.948e-60	216.0	COG0457@1|root,COG1994@1|root,COG0457@2|Bacteria,COG1994@2|Bacteria,1G1EH@1117|Cyanobacteria,1HAWT@1150|Oscillatoriales	1117|Cyanobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
REGS1_k127_680318_0	1122947.FR7_0942	1.427e-142	464.0	COG1252@1|root,COG1252@2|Bacteria,1TR6X@1239|Firmicutes,4H3UJ@909932|Negativicutes	909932|Negativicutes	C	pyridine nucleotide-disulfide oxidoreductase	-	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_680318_8	56780.SYN_01375	3.547e-36	140.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,42U37@68525|delta/epsilon subdivisions,2WQ9M@28221|Deltaproteobacteria,2MRZA@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
REGS1_k127_680318_9	1116472.MGMO_8c00150	6.157e-35	138.0	2E3V1@1|root,32YSA@2|Bacteria,1N7HB@1224|Proteobacteria,1SF7K@1236|Gammaproteobacteria,1XGMP@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_680318_6	1462527.CCDM010000004_gene3609	2.694e-57	211.0	COG0122@1|root,COG0122@2|Bacteria	2|Bacteria	L	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
REGS1_k127_680318_5	266117.Rxyl_2427	8.797e-58	212.0	2DBRF@1|root,2ZAKB@2|Bacteria,2IIVX@201174|Actinobacteria,4CQPW@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_680318_7	66874.JOFS01000010_gene4904	5.815e-43	162.0	COG2606@1|root,COG2606@2|Bacteria,2IMZE@201174|Actinobacteria	201174|Actinobacteria	G	Aminoacyl-tRNA editing domain	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
REGS1_k127_680318_10	315750.BPUM_3683	2.128e-33	134.0	COG0454@1|root,COG0456@2|Bacteria,1VAU8@1239|Firmicutes,4HMA6@91061|Bacilli,1ZFP4@1386|Bacillus	91061|Bacilli	K	Acetyltransferase	yycN	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_680318_2	517418.Ctha_2426	2.176e-117	385.0	COG0366@1|root,COG0366@2|Bacteria,1FFH6@1090|Chlorobi	1090|Chlorobi	C	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
REGS1_k127_6818566_3	1306990.BARG01000121_gene10170	2.73e-23	106.0	COG1653@1|root,COG1653@2|Bacteria,2H1PF@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
REGS1_k127_6818566_2	345341.KUTG_08740	4.713e-64	232.0	COG1175@1|root,COG1175@2|Bacteria,2IAEF@201174|Actinobacteria,4E9CM@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
REGS1_k127_6818566_1	33876.JNXY01000002_gene346	7.631e-83	285.0	COG0395@1|root,COG0395@2|Bacteria,2GJPZ@201174|Actinobacteria,4DBAP@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
REGS1_k127_6818566_0	926550.CLDAP_12850	2.104e-217	682.0	COG1486@1|root,COG1486@2|Bacteria,2G5KA@200795|Chloroflexi	200795|Chloroflexi	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
REGS1_k127_6824445_1	926550.CLDAP_11000	1.214e-90	302.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
REGS1_k127_6824445_0	926569.ANT_31100	3.227e-149	490.0	COG0747@1|root,COG0747@2|Bacteria,2G7MC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_6843038_3	926550.CLDAP_11310	1.33e-85	289.0	COG0559@1|root,COG0559@2|Bacteria,2G6FM@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_6843038_0	926550.CLDAP_11300	1.262e-137	451.0	COG4177@1|root,COG4177@2|Bacteria,2G6D8@200795|Chloroflexi	200795|Chloroflexi	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_6843038_1	1521187.JPIM01000109_gene950	3.864e-98	327.0	COG0411@1|root,COG0411@2|Bacteria,2G5W6@200795|Chloroflexi,374Z9@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_6843038_2	383372.Rcas_1896	1.078e-95	319.0	COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374YI@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
REGS1_k127_6896746_1	926550.CLDAP_40040	1.111e-33	141.0	COG0526@1|root,COG0526@2|Bacteria,2G737@200795|Chloroflexi	200795|Chloroflexi	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,DnaJ
REGS1_k127_6896746_2	926569.ANT_26580	7.102e-15	77.0	COG3462@1|root,COG3462@2|Bacteria	2|Bacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
REGS1_k127_6896746_0	926550.CLDAP_14470	1.11e-264	826.0	COG2217@1|root,COG2217@2|Bacteria	2|Bacteria	P	Heavy metal translocating P-type atpase	copB	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase
REGS1_k127_6924643_8	497964.CfE428DRAFT_3398	7.119e-47	186.0	COG3966@1|root,COG3966@2|Bacteria	2|Bacteria	M	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)	dltD	-	-	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	DltD
REGS1_k127_6924643_11	646529.Desaci_3378	4.509e-15	77.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	dltC	GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K02078,ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	PP-binding
REGS1_k127_6924643_1	383372.Rcas_0076	4.035e-160	528.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2G5QB@200795|Chloroflexi,3756Y@32061|Chloroflexia	32061|Chloroflexia	C	TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
REGS1_k127_6924643_9	1121272.KB903249_gene2255	4.068e-41	158.0	COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_6924643_2	926569.ANT_11990	2.067e-151	492.0	COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi	200795|Chloroflexi	H	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	-	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
REGS1_k127_6924643_5	926569.ANT_12000	4.627e-106	363.0	COG0006@1|root,COG0006@2|Bacteria,2G5J6@200795|Chloroflexi	200795|Chloroflexi	C	Metallopeptidase family M24	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
REGS1_k127_6924643_4	926569.ANT_12010	1.1e-137	447.0	COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi	200795|Chloroflexi	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_6924643_7	1382359.JIAL01000001_gene24	2.999e-50	186.0	COG0009@1|root,COG0009@2|Bacteria,3Y3VW@57723|Acidobacteria,2JHTT@204432|Acidobacteriia	204432|Acidobacteriia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
REGS1_k127_6924643_6	926569.ANT_09630	1.221e-73	257.0	COG2890@1|root,COG2890@2|Bacteria,2G6I8@200795|Chloroflexi	200795|Chloroflexi	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
REGS1_k127_6924643_3	926569.ANT_09640	7.757e-149	480.0	COG0216@1|root,COG0216@2|Bacteria,2G5UD@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_6924643_0	926569.ANT_05230	1.42e-275	859.0	COG0322@1|root,COG0322@2|Bacteria,2G651@200795|Chloroflexi	200795|Chloroflexi	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
REGS1_k127_6924643_12	926550.CLDAP_15590	2.962e-07	58.0	2FKQZ@1|root,30TRG@2|Bacteria,2G9KN@200795|Chloroflexi	200795|Chloroflexi	S	Yip1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Yip1
REGS1_k127_6961437_0	251229.Chro_2922	3.555e-177	565.0	28IMC@1|root,2Z8MV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6961437_1	1449126.JQKL01000008_gene239	2.484e-85	292.0	COG0413@1|root,COG0413@2|Bacteria,1TPZA@1239|Firmicutes,248RR@186801|Clostridia	186801|Clostridia	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
REGS1_k127_6961437_2	1382356.JQMP01000004_gene492	9.233e-82	284.0	COG1506@1|root,COG1506@2|Bacteria,2G8QF@200795|Chloroflexi,27YT1@189775|Thermomicrobia	189775|Thermomicrobia	E	Alpha/beta hydrolase of unknown function (DUF1100)	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
REGS1_k127_6966807_2	765420.OSCT_2955	7.182e-91	310.0	COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,374SV@32061|Chloroflexia	32061|Chloroflexia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
REGS1_k127_6966807_1	5039.XP_002622471.1	6.079e-167	540.0	COG0520@1|root,KOG2142@2759|Eukaryota,38F30@33154|Opisthokonta,3NY5Z@4751|Fungi,3QREF@4890|Ascomycota,20FDX@147545|Eurotiomycetes,3B2AK@33183|Onygenales	4751|Fungi	H	Molybdenum cofactor sulfurase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
REGS1_k127_6966807_3	1395587.P364_0110155	4.415e-23	100.0	COG4895@1|root,COG4895@2|Bacteria,1VEG3@1239|Firmicutes,4HNJA@91061|Bacilli,26ZRV@186822|Paenibacillaceae	91061|Bacilli	S	Uncharacterized conserved protein (DUF2196)	ywbE	-	-	-	-	-	-	-	-	-	-	-	DUF2196
REGS1_k127_6966807_5	1463879.JOHP01000009_gene689	1.654e-08	61.0	COG0346@1|root,COG0346@2|Bacteria,2II62@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_6966807_0	1499967.BAYZ01000060_gene6002	1.074e-182	597.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
REGS1_k127_6966807_4	658086.HMPREF0994_02145	5.626e-14	76.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,27IG8@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
REGS1_k127_6984605_2	926569.ANT_27830	3.554e-117	390.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
REGS1_k127_6984605_13	926569.ANT_17460	3.038e-39	163.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027,ko:K10117,ko:K17318	ko02010,map02010	M00196,M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
REGS1_k127_6984605_12	1121380.JNIW01000099_gene65	1.561e-39	163.0	COG0477@1|root,COG2814@2|Bacteria,1WJCM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
REGS1_k127_6984605_7	926569.ANT_13140	1.499e-52	193.0	COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM sigma-70 region 2 domain protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_6984605_11	926569.ANT_13160	1.317e-42	169.0	COG1664@1|root,COG1664@2|Bacteria,2G7EZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_6984605_9	309801.trd_1743	1.164e-48	188.0	COG4927@1|root,COG4927@2|Bacteria,2GA59@200795|Chloroflexi,27ZAW@189775|Thermomicrobia	189775|Thermomicrobia	S	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
REGS1_k127_6984605_6	926569.ANT_06830	8.484e-63	222.0	COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi	200795|Chloroflexi	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
REGS1_k127_6984605_0	926569.ANT_06840	1.427e-198	628.0	COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi	200795|Chloroflexi	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
REGS1_k127_6984605_14	1128421.JAGA01000004_gene2549	5.298e-28	123.0	COG3935@1|root,COG3935@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K02086	-	-	-	-	ko00000	-	-	-	DnaB_2,HTH_36,RepA_N
REGS1_k127_6984605_1	926569.ANT_06860	5.187e-164	528.0	COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi	200795|Chloroflexi	L	PFAM IstB domain protein ATP-binding protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
REGS1_k127_6984605_5	318424.EU78_28035	1.624e-67	238.0	COG0428@1|root,COG0428@2|Bacteria,2IBHZ@201174|Actinobacteria,238Q9@1762|Mycobacteriaceae	201174|Actinobacteria	P	Zinc permease	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
REGS1_k127_6984605_10	926569.ANT_00450	9.7e-45	166.0	COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi	200795|Chloroflexi	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	HTH_5,LMWPc
REGS1_k127_6984605_4	1382356.JQMP01000004_gene657	2.95e-71	248.0	COG0704@1|root,COG0704@2|Bacteria,2G6HD@200795|Chloroflexi,27XPS@189775|Thermomicrobia	189775|Thermomicrobia	P	Plays a role in the regulation of phosphate uptake	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
REGS1_k127_6984605_3	552811.Dehly_1322	3.986e-108	356.0	COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi,34D5U@301297|Dehalococcoidia	301297|Dehalococcoidia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
REGS1_k127_6984605_8	448385.sce2944	1.047e-49	184.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WMUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
REGS1_k127_6995129_0	56110.Oscil6304_3204	4.218e-81	305.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria	2|Bacteria	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_7,PAS_9,Response_reg
REGS1_k127_7013536_4	926569.ANT_04230	3.207e-107	357.0	COG0303@1|root,COG0303@2|Bacteria,2G6F6@200795|Chloroflexi	200795|Chloroflexi	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
REGS1_k127_7013536_15	324602.Caur_3426	7.78e-11	72.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.39,2.5.1.42,2.5.1.74	ko:K02548,ko:K03179,ko:K17105	ko00130,ko00564,ko01100,ko01110,map00130,map00564,map01100,map01110	M00116,M00117	R04520,R05000,R05615,R05617,R06858,R10757	RC00209,RC01171,RC02895,RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	Flavodoxin_2,UbiA
REGS1_k127_7013536_16	558152.IQ37_11810	0.0005507	48.0	2AYX9@1|root,31R2Z@2|Bacteria,4NNS4@976|Bacteroidetes,1I8KU@117743|Flavobacteriia	976|Bacteroidetes	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_7013536_10	316274.Haur_2919	6.809e-46	174.0	COG1028@1|root,COG1028@2|Bacteria,2G8K5@200795|Chloroflexi,3779V@32061|Chloroflexia	32061|Chloroflexia	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
REGS1_k127_7013536_5	926569.ANT_04210	1.728e-101	339.0	COG0506@1|root,COG0506@2|Bacteria,2G6B6@200795|Chloroflexi	200795|Chloroflexi	C	Proline dehydrogenase	-	-	-	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	-	R10507	RC00083	ko00000,ko00001,ko01000	-	-	-	Pro_dh
REGS1_k127_7013536_2	926569.ANT_12990	4.476e-153	505.0	COG2367@1|root,COG2367@2|Bacteria,2G75H@200795|Chloroflexi	200795|Chloroflexi	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
REGS1_k127_7013536_12	926569.ANT_18410	4.243e-41	161.0	COG1579@1|root,COG1579@2|Bacteria,2G775@200795|Chloroflexi	200795|Chloroflexi	S	Zn-ribbon protein possibly nucleic acid-binding	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
REGS1_k127_7013536_14	926569.ANT_18420	2.367e-21	103.0	COG1413@1|root,COG5635@1|root,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	DNA_alkylation,GUN4,HEAT_2,Mrr_cat,NACHT
REGS1_k127_7013536_1	926569.ANT_14390	1.14e-174	559.0	COG0402@1|root,COG0402@2|Bacteria,2G7M9@200795|Chloroflexi	200795|Chloroflexi	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
REGS1_k127_7013536_7	926569.ANT_14400	6.033e-76	261.0	COG2085@1|root,COG2085@2|Bacteria,2G7DD@200795|Chloroflexi	200795|Chloroflexi	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
REGS1_k127_7013536_6	926569.ANT_14410	3.996e-94	316.0	COG1478@1|root,COG1478@2|Bacteria,2G5TU@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM F420-dependent oxidoreductase	-	-	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase
REGS1_k127_7013536_13	926569.ANT_04680	3.823e-29	120.0	COG3467@1|root,COG3467@2|Bacteria,2G77X@200795|Chloroflexi	200795|Chloroflexi	S	PFAM pyridoxamine 5'-phosphate oxidase-related	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
REGS1_k127_7013536_9	926550.CLDAP_12770	3.289e-48	179.0	COG0778@1|root,COG0778@2|Bacteria,2G693@200795|Chloroflexi	200795|Chloroflexi	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_7013536_3	926569.ANT_14430	2.924e-112	376.0	COG0391@1|root,COG0391@2|Bacteria,2G5S2@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM LPPG domain protein containing protein	cofD	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
REGS1_k127_7013536_11	926569.ANT_14440	5.209e-43	164.0	COG1920@1|root,COG1920@2|Bacteria,2G76R@200795|Chloroflexi	200795|Chloroflexi	H	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC
REGS1_k127_7013536_0	459349.CLOAM1631	4.42e-176	570.0	COG0167@1|root,COG0493@1|root,COG1148@1|root,COG0167@2|Bacteria,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	pds	-	1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9	ko:K00207,ko:K00219,ko:K00317,ko:K02293,ko:K10797,ko:K12527,ko:K17723	ko00240,ko00360,ko00410,ko00450,ko00680,ko00770,ko00906,ko00983,ko01100,ko01110,ko01120,ko01200,map00240,map00360,map00410,map00450,map00680,map00770,map00906,map00983,map01100,map01110,map01120,map01200	M00046,M00097	R00977,R00978,R01414,R01415,R01588,R02252,R02511,R04786,R04787,R07229,R07510,R08226,R09652,R09653,R09654,R11026	RC00072,RC00123,RC00185,RC00556,RC00557,RC00669,RC00732,RC01214,RC01958,RC02245,RC02420,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4,Fer4_4,Pyr_redox_2
REGS1_k127_7020680_2	926569.ANT_01460	3.482e-49	179.0	COG1159@1|root,COG1159@2|Bacteria,2G69C@200795|Chloroflexi	200795|Chloroflexi	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
REGS1_k127_7020680_0	926569.ANT_02930	5.06e-108	358.0	COG1284@1|root,COG1284@2|Bacteria,2G6SY@200795|Chloroflexi	200795|Chloroflexi	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
REGS1_k127_7020680_1	5679.XP_010701054.1	5.843e-106	351.0	COG2084@1|root,KOG0409@2759|Eukaryota,3XS8U@5653|Kinetoplastida	5653|Kinetoplastida	E	2-hydroxy-3-oxopropionate reductase	-	-	1.1.1.60	ko:K00042	ko00630,ko01100,map00630,map01100	-	R01745,R01747	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
REGS1_k127_7034520_13	926569.ANT_29210	8.385e-26	123.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	-	-	-	-	-	-	-	-	-	Wzy_C
REGS1_k127_7034520_1	926569.ANT_06580	2.177e-121	394.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
REGS1_k127_7034520_10	118168.MC7420_7338	3.231e-60	219.0	2DTTJ@1|root,32UVW@2|Bacteria,1G8TS@1117|Cyanobacteria,1HCTF@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
REGS1_k127_7034520_6	926569.ANT_06560	1.047e-89	316.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
REGS1_k127_7034520_5	926569.ANT_06540	3.316e-90	309.0	COG1215@1|root,COG1215@2|Bacteria,2G8MG@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_7034520_9	926569.ANT_06560	2.661e-65	242.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
REGS1_k127_7034520_4	926569.ANT_06530	6.581e-98	326.0	COG2604@1|root,COG2604@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF115	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,DUF2920,MAF_flag10
REGS1_k127_7034520_3	926569.ANT_06520	3.726e-109	358.0	COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi	200795|Chloroflexi	IQ	PFAM short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
REGS1_k127_7034520_0	926569.ANT_06500	1.901e-130	423.0	COG0111@1|root,COG0111@2|Bacteria	2|Bacteria	EH	4-phosphoerythronate dehydrogenase activity	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
REGS1_k127_7034520_7	926569.ANT_06490	9.089e-84	284.0	COG1083@1|root,COG1083@2|Bacteria	2|Bacteria	M	cytidylyl-transferase	-	-	2.7.7.43	ko:K00983	ko00520,ko01100,map00520,map01100	-	R01117,R04215	RC00152	ko00000,ko00001,ko01000	-	-	-	CTP_transf_3,RraA-like
REGS1_k127_7034520_12	706587.Desti_2618	3.418e-33	150.0	COG0664@1|root,COG1413@1|root,COG3202@1|root,COG0664@2|Bacteria,COG1413@2|Bacteria,COG3202@2|Bacteria	2|Bacteria	C	ATP:ADP antiporter activity	CP_0465	-	-	ko:K15762	ko00623,ko00920,ko01100,ko01120,ko01220,map00623,map00920,map01100,map01120,map01220	M00538	R02550,R03562,R05666,R09513	RC00269,RC00490,RC02556	ko00000,ko00001,ko00002	-	-	-	HEAT_2,HTH_Crp_2,cNMP_binding
REGS1_k127_7034520_2	1101188.KI912155_gene1695	1.966e-117	391.0	COG3511@1|root,COG3511@2|Bacteria,2GKPN@201174|Actinobacteria	201174|Actinobacteria	M	phospholipase C	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
REGS1_k127_7049514_0	204669.Acid345_0397	1.222e-150	482.0	COG0726@1|root,COG1215@1|root,COG3858@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,COG3858@2|Bacteria,3Y3WI@57723|Acidobacteria,2JI39@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Polysacc_deac_1
REGS1_k127_7049514_1	204669.Acid345_3931	2.728e-28	115.0	COG3033@1|root,COG3033@2|Bacteria,3Y3QK@57723|Acidobacteria	57723|Acidobacteria	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
REGS1_k127_7060528_12	1211817.CCAT010000044_gene3323	6.297e-32	139.0	COG0687@1|root,COG1177@1|root,COG0687@2|Bacteria,COG1177@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,36DK4@31979|Clostridiaceae	186801|Clostridia	P	Spermidine putrescine-binding periplasmic protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
REGS1_k127_7060528_8	1183438.GKIL_2741	5.02e-101	337.0	COG1176@1|root,COG1176@2|Bacteria,1G127@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC-type spermidine putrescine transport system, permease component I	potB	-	-	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	BPD_transp_1
REGS1_k127_7060528_5	324602.Caur_1681	7.991e-132	430.0	COG3842@1|root,COG3842@2|Bacteria,2G62V@200795|Chloroflexi,3758E@32061|Chloroflexia	32061|Chloroflexia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
REGS1_k127_7060528_0	306281.AJLK01000030_gene1328	1.051e-218	688.0	COG1012@1|root,COG1012@2|Bacteria,1G09W@1117|Cyanobacteria,1JHZW@1189|Stigonemataceae	1117|Cyanobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_7060528_2	1121381.JNIV01000042_gene2024	2.538e-164	528.0	COG0161@1|root,COG0161@2|Bacteria,1WISD@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Aminotransferase class-III	-	-	2.6.1.55	ko:K15372	ko00410,ko00430,ko01100,map00410,map00430,map01100	-	R00908,R01684	RC00006,RC00062	ko00000,ko00001,ko01000	-	-	-	Aminotran_3
REGS1_k127_7060528_4	476272.RUMHYD_02346	3.426e-150	486.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_7060528_14	573063.Metin_1144	3.223e-12	74.0	COG1522@1|root,arCOG01580@2157|Archaea,2XX3W@28890|Euryarchaeota,23QY6@183939|Methanococci	183939|Methanococci	K	PFAM regulatory protein AsnC Lrp family	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
REGS1_k127_7060528_9	926569.ANT_25400	9.479e-56	204.0	COG0539@1|root,COG0539@2|Bacteria,2G90B@200795|Chloroflexi	200795|Chloroflexi	J	PFAM RNA binding S1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S1
REGS1_k127_7060528_6	1191523.MROS_0836	3.092e-118	400.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,PP-binding
REGS1_k127_7060528_15	1171373.PACID_19450	2.397e-05	49.0	COG0236@1|root,COG0236@2|Bacteria,2H7G5@201174|Actinobacteria,4DW64@85009|Propionibacteriales	201174|Actinobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7060528_11	1157490.EL26_06100	2.358e-48	191.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli,278S2@186823|Alicyclobacillaceae	91061|Bacilli	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
REGS1_k127_7060528_3	926569.ANT_16650	2.648e-152	488.0	COG1186@1|root,COG1186@2|Bacteria,2G5P6@200795|Chloroflexi	200795|Chloroflexi	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_7060528_7	926569.ANT_16640	2.69e-115	379.0	COG0552@1|root,COG0552@2|Bacteria,2G63M@200795|Chloroflexi	200795|Chloroflexi	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
REGS1_k127_7060528_10	926569.ANT_15100	3.397e-55	196.0	COG3118@1|root,COG3118@2|Bacteria,2G6U1@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the thioredoxin family	-	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_7060528_1	926569.ANT_11050	8.866e-198	624.0	COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi	200795|Chloroflexi	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
REGS1_k127_7060528_13	926569.ANT_14580	9.679e-32	133.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	comC	-	3.4.23.43	ko:K02236,ko:K02506,ko:K02654	-	M00331,M00429	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
REGS1_k127_708135_3	926569.ANT_26670	2.202e-19	87.0	COG0459@1|root,COG0459@2|Bacteria,2G65N@200795|Chloroflexi	200795|Chloroflexi	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
REGS1_k127_708135_1	1128421.JAGA01000003_gene2785	5.623e-55	205.0	COG0472@1|root,COG0472@2|Bacteria,2NR03@2323|unclassified Bacteria	2|Bacteria	M	Glycosyl transferase family 4	-	-	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	CoA_binding_3,Glycos_transf_4
REGS1_k127_708135_0	1249634.D781_1368	3.805e-84	287.0	COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,1MVN5@1224|Proteobacteria,1RP6D@1236|Gammaproteobacteria,40253@613|Serratia	1236|Gammaproteobacteria	L	Transposase	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
REGS1_k127_708135_2	608506.COB47_0049	1.275e-54	201.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,42J3Y@68295|Thermoanaerobacterales	186801|Clostridia	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
REGS1_k127_708135_4	1263831.F543_3950	1.877e-05	54.0	COG1134@1|root,COG1134@2|Bacteria,1MWWC@1224|Proteobacteria,1RN2T@1236|Gammaproteobacteria,1Y7MK@135625|Pasteurellales	135625|Pasteurellales	GM	ABC transporter ATP binding subunit of Bacteria UniRef RepID Q9AQB5_AGGAC	-	-	-	ko:K09691	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC_tran
REGS1_k127_7101453_4	196367.JNFG01000007_gene6765	7.501e-32	126.0	COG0526@1|root,COG0526@2|Bacteria,1RA5V@1224|Proteobacteria,2VQX7@28216|Betaproteobacteria,1KFIZ@119060|Burkholderiaceae	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
REGS1_k127_7101453_0	1521187.JPIM01000134_gene1347	2.29e-123	403.0	COG2041@1|root,COG2041@2|Bacteria,2G618@200795|Chloroflexi,375BB@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	msrP	-	-	ko:K07147	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_molyb
REGS1_k127_7101453_2	357808.RoseRS_1504	2.42e-48	181.0	COG2717@1|root,COG2717@2|Bacteria,2G6WP@200795|Chloroflexi,375NC@32061|Chloroflexia	32061|Chloroflexia	C	Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain	msrQ	-	-	ko:K17247	-	-	-	-	ko00000	-	-	-	Ferric_reduct
REGS1_k127_7101453_5	1321778.HMPREF1982_02132	4.365e-11	66.0	2AFI1@1|root,315IM@2|Bacteria,1UUJJ@1239|Firmicutes,256YF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7101453_3	290397.Adeh_3950	2.082e-39	158.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
REGS1_k127_7101453_1	926569.ANT_28360	1.13e-87	295.0	COG1428@1|root,COG1428@2|Bacteria,2G8PM@200795|Chloroflexi	200795|Chloroflexi	F	PFAM deoxynucleoside kinase	-	-	-	-	-	-	-	-	-	-	-	-	dNK
REGS1_k127_712952_1	383372.Rcas_1237	2.007e-105	345.0	COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi,37726@32061|Chloroflexia	32061|Chloroflexia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
REGS1_k127_712952_2	1381123.AYOD01000043_gene1445	9.925e-80	282.0	COG1177@1|root,COG1177@2|Bacteria,1MV4A@1224|Proteobacteria,2TUA3@28211|Alphaproteobacteria,43IW3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_712952_0	926569.ANT_31320	2.456e-111	368.0	COG4132@1|root,COG4132@2|Bacteria,2G69Y@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_712952_3	1122132.AQYH01000019_gene342	1.395e-15	78.0	COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,2TS7Y@28211|Alphaproteobacteria,4B8Z6@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
REGS1_k127_7135480_3	926569.ANT_21000	4.565e-48	178.0	COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi	200795|Chloroflexi	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
REGS1_k127_7135480_0	1449336.JQLO01000001_gene557	4.749e-87	293.0	COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli,27FDQ@186828|Carnobacteriaceae	91061|Bacilli	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodA	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
REGS1_k127_7135480_1	926569.ANT_21020	1.616e-65	236.0	COG0697@1|root,COG0697@2|Bacteria,2G70T@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_7135480_4	1242864.D187_003027	1.094e-45	171.0	COG2940@1|root,COG2940@2|Bacteria,1MWFB@1224|Proteobacteria	1224|Proteobacteria	S	Nuclear protein SET	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
REGS1_k127_7135480_5	926569.ANT_08490	1.806e-42	161.0	COG1664@1|root,COG1664@2|Bacteria,2G7DZ@200795|Chloroflexi	200795|Chloroflexi	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_7135480_2	926569.ANT_08470	2.103e-65	238.0	COG0442@1|root,COG0442@2|Bacteria,2G5Q6@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
REGS1_k127_7158235_1	198214.SF2952	6.721e-24	105.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,1RNAM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
REGS1_k127_7158235_2	1121929.KB898673_gene3944	5.723e-18	91.0	COG3090@1|root,COG3090@2|Bacteria,1VFA6@1239|Firmicutes,4HNAC@91061|Bacilli,4716J@74385|Gracilibacillus	91061|Bacilli	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
REGS1_k127_7158235_0	1124991.MU9_382	2.089e-31	128.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,1RPNJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	transporter	-	-	-	-	-	-	-	-	-	-	-	-	DctP
REGS1_k127_7188738_3	1267535.KB906767_gene1310	6.312e-15	75.0	COG0542@1|root,COG0542@2|Bacteria,3Y35D@57723|Acidobacteria,2JIRK@204432|Acidobacteriia	57723|Acidobacteria	O	Belongs to the ClpA ClpB family	-	-	-	-	-	-	-	-	-	-	-	-	Clp_N
REGS1_k127_7188738_2	1267535.KB906767_gene1033	4.249e-31	125.0	COG1993@1|root,COG1993@2|Bacteria,3Y605@57723|Acidobacteria,2JM1G@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
REGS1_k127_7188738_1	1267535.KB906767_gene1034	2.232e-77	267.0	COG1993@1|root,COG1993@2|Bacteria,3Y605@57723|Acidobacteria,2JM1G@204432|Acidobacteriia	204432|Acidobacteriia	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
REGS1_k127_7188738_0	234267.Acid_4547	2.484e-127	411.0	COG5285@1|root,COG5285@2|Bacteria,3Y7AJ@57723|Acidobacteria	57723|Acidobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
REGS1_k127_71944_9	706587.Desti_3197	0.0002298	44.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_71944_0	1121324.CLIT_10c01870	6.642e-156	507.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia	186801|Clostridia	V	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
REGS1_k127_71944_1	323848.Nmul_A0150	2.79e-120	416.0	COG0421@1|root,COG0477@1|root,COG0421@2|Bacteria,COG2814@2|Bacteria,1P220@1224|Proteobacteria,2VNDM@28216|Betaproteobacteria,372RG@32003|Nitrosomonadales	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_71944_4	1408473.JHXO01000008_gene2892	7.707e-65	231.0	COG2518@1|root,COG2518@2|Bacteria,4NMTP@976|Bacteroidetes,2FXTG@200643|Bacteroidia	976|Bacteroidetes	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_71944_3	485913.Krac_11703	4.338e-85	286.0	COG0302@1|root,COG0302@2|Bacteria,2G6VZ@200795|Chloroflexi	2|Bacteria	H	PFAM GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
REGS1_k127_71944_6	1381751.JAJB01000014_gene2137	2.016e-26	113.0	COG0346@1|root,COG0346@2|Bacteria,2IHNJ@201174|Actinobacteria,4FABY@85019|Brevibacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	gloA	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_71944_8	309801.trd_1501	6.549e-20	97.0	COG1595@1|root,COG1595@2|Bacteria,2G99U@200795|Chloroflexi,27YIE@189775|Thermomicrobia	189775|Thermomicrobia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_71944_7	383372.Rcas_2698	2.604e-25	119.0	COG5662@1|root,COG5662@2|Bacteria,2G7G7@200795|Chloroflexi	200795|Chloroflexi	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_71944_2	526227.Mesil_0789	6.994e-102	340.0	COG1131@1|root,COG1131@2|Bacteria,1WJ0H@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_71944_5	357808.RoseRS_3279	1.321e-57	214.0	COG1277@1|root,COG1277@2|Bacteria,2G79P@200795|Chloroflexi	200795|Chloroflexi	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
REGS1_k127_7194514_3	272631.ML0320	1.068e-10	68.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,234B7@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcription factor CarD	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
REGS1_k127_7194514_1	1191523.MROS_0149	2.314e-57	207.0	COG0558@1|root,COG0558@2|Bacteria	2|Bacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.39	ko:K17884	-	-	R10464	RC00002,RC00078	ko00000,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_7194514_2	926569.ANT_27210	8.671e-43	170.0	COG1560@1|root,COG1560@2|Bacteria	2|Bacteria	M	Kdo2-lipid A biosynthetic process	-	-	2.3.1.241,2.3.1.265	ko:K02517,ko:K20543,ko:K22311	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	1.B.55.3	-	-	Lip_A_acyltrans,TPR_19
REGS1_k127_7194514_0	926569.ANT_17670	2.409e-226	711.0	COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi	200795|Chloroflexi	O	PFAM magnesium chelatase ChlI subunit	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
REGS1_k127_7196015_11	926550.CLDAP_20690	1.679e-97	331.0	COG0577@1|root,COG0577@2|Bacteria,2G6RX@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
REGS1_k127_7196015_20	926550.CLDAP_20700	9.287e-76	268.0	COG1136@1|root,COG1136@2|Bacteria,2G6K8@200795|Chloroflexi	200795|Chloroflexi	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_7196015_4	1499967.BAYZ01000119_gene3222	3.187e-162	522.0	COG0174@1|root,COG0174@2|Bacteria,2NNY0@2323|unclassified Bacteria	2|Bacteria	E	glutamine synthetase	glnA2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
REGS1_k127_7196015_17	1227352.C173_27310	1.155e-79	275.0	COG0697@1|root,COG0697@2|Bacteria,1UZ6C@1239|Firmicutes,4HKQT@91061|Bacilli,26WER@186822|Paenibacillaceae	91061|Bacilli	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_7196015_14	1278073.MYSTI_06515	1.031e-90	308.0	COG0350@1|root,COG2207@1|root,COG0350@2|Bacteria,COG2207@2|Bacteria,1N2YQ@1224|Proteobacteria,42MQN@68525|delta/epsilon subdivisions,2WRJ0@28221|Deltaproteobacteria,2YZ2C@29|Myxococcales	28221|Deltaproteobacteria	K	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	DNA_binding_1,HTH_18,Methyltransf_1N
REGS1_k127_7196015_37	357808.RoseRS_2594	6.836e-14	74.0	COG1231@1|root,COG1231@2|Bacteria,2G942@200795|Chloroflexi	200795|Chloroflexi	E	PFAM amine oxidase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
REGS1_k127_7196015_21	926569.ANT_15050	3.68e-62	226.0	COG0805@1|root,COG0805@2|Bacteria,2G6SP@200795|Chloroflexi	200795|Chloroflexi	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
REGS1_k127_7196015_38	926569.ANT_15060	5.531e-12	71.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_7196015_22	926569.ANT_14610	7.021e-56	199.0	COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi	200795|Chloroflexi	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
REGS1_k127_7196015_36	926569.ANT_14620	4.509e-24	106.0	COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi	200795|Chloroflexi	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
REGS1_k127_7196015_19	1122216.AUHW01000012_gene1550	1.831e-76	263.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4H2JC@909932|Negativicutes	909932|Negativicutes	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_7196015_27	926569.ANT_20710	1.859e-43	169.0	COG4478@1|root,COG4478@2|Bacteria,2G9EA@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1461
REGS1_k127_7196015_3	926569.ANT_20700	1.159e-170	553.0	COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi	200795|Chloroflexi	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
REGS1_k127_7196015_24	1191523.MROS_0095	6.316e-50	186.0	COG0235@1|root,COG0235@2|Bacteria	2|Bacteria	G	Class ii aldolase	fucA	-	2.7.1.189,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K11216	ko00040,ko00051,ko00053,ko01100,ko01120,ko02024,map00040,map00051,map00053,map01100,map01120,map02024	M00550	R02262,R05850,R11183	RC00002,RC00017,RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
REGS1_k127_7196015_6	926569.ANT_16190	4.832e-126	412.0	COG0182@1|root,COG0182@2|Bacteria,2G5Z3@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
REGS1_k127_7196015_23	926569.ANT_14790	2.849e-55	202.0	COG1825@1|root,COG1825@2|Bacteria,2G7A4@200795|Chloroflexi	200795|Chloroflexi	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
REGS1_k127_7196015_25	926569.ANT_14780	3.627e-47	177.0	COG0494@1|root,COG0494@2|Bacteria,2G7AT@200795|Chloroflexi	200795|Chloroflexi	L	PFAM NUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_7196015_9	926569.ANT_14770	1.031e-104	347.0	COG2519@1|root,COG2519@2|Bacteria,2G8GD@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14
REGS1_k127_7196015_39	1172188.KB911824_gene3257	8.183e-06	58.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4FF1U@85021|Intrasporangiaceae	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
REGS1_k127_7196015_13	926569.ANT_30890	3.972e-94	327.0	COG0652@1|root,COG1651@1|root,COG0652@2|Bacteria,COG1651@2|Bacteria,2G8IA@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase,Thioredoxin_4
REGS1_k127_7196015_8	926569.ANT_30540	9.317e-119	395.0	2EZVX@1|root,33T0B@2|Bacteria,2G87X@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7196015_2	686340.Metal_0046	8.912e-177	559.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,1RP2I@1236|Gammaproteobacteria,1XF21@135618|Methylococcales	135618|Methylococcales	P	PFAM Bile acid sodium symporter	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
REGS1_k127_7196015_34	1114970.PSF113_2061	2.271e-25	108.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria	1224|Proteobacteria	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
REGS1_k127_7196015_30	643648.Slip_2185	7.608e-35	138.0	COG1764@1|root,COG1764@2|Bacteria,1VYMJ@1239|Firmicutes,2538T@186801|Clostridia	186801|Clostridia	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
REGS1_k127_7196015_31	643648.Slip_2186	2.241e-34	141.0	COG4273@1|root,COG4273@2|Bacteria,1UPTR@1239|Firmicutes,25HNZ@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
REGS1_k127_7196015_33	643648.Slip_2187	1.587e-27	117.0	COG4273@1|root,COG4273@2|Bacteria,1VBRH@1239|Firmicutes,24N2C@186801|Clostridia	186801|Clostridia	S	DGC domain	-	-	-	-	-	-	-	-	-	-	-	-	DGC
REGS1_k127_7196015_29	643648.Slip_2188	5.642e-38	147.0	COG0509@1|root,COG0509@2|Bacteria,1V6WV@1239|Firmicutes,24N5H@186801|Clostridia,42K4C@68298|Syntrophomonadaceae	186801|Clostridia	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	DGC,GCV_H
REGS1_k127_7196015_32	926569.ANT_03520	6.919e-28	118.0	COG0640@1|root,COG0640@2|Bacteria,2G980@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
REGS1_k127_7196015_7	477974.Daud_0551	3.127e-121	406.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,260CB@186807|Peptococcaceae	186801|Clostridia	C	glutamate synthase (NADPH), homotetrameric	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
REGS1_k127_7196015_16	926569.ANT_07670	2.359e-84	296.0	COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi	200795|Chloroflexi	M	PFAM secretion protein HlyD family protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_7196015_15	926550.CLDAP_19390	5.708e-86	293.0	COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi	200795|Chloroflexi	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_7196015_5	926569.ANT_07650	6.33e-161	516.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_7196015_10	926569.ANT_07000	5.015e-102	340.0	COG0111@1|root,COG0111@2|Bacteria,2G67B@200795|Chloroflexi	200795|Chloroflexi	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
REGS1_k127_7196015_0	926569.ANT_06990	9.473e-200	633.0	COG2317@1|root,COG2317@2|Bacteria,2G7UQ@200795|Chloroflexi	200795|Chloroflexi	E	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues	-	-	3.4.17.19	ko:K01299	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M32
REGS1_k127_7196015_35	926569.ANT_06090	4.869e-25	117.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,WXG100
REGS1_k127_7196015_12	386456.JQKN01000011_gene815	2.014e-97	333.0	COG2239@1|root,arCOG00634@2157|Archaea,2XWIB@28890|Euryarchaeota,23PEC@183925|Methanobacteria	183925|Methanobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
REGS1_k127_7196015_18	521460.Athe_0657	3.554e-78	280.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,24ACU@186801|Clostridia,42F5H@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
REGS1_k127_7196015_26	880073.Calab_2505	8.483e-45	166.0	COG2905@1|root,COG2905@2|Bacteria,2NQ7R@2323|unclassified Bacteria	2|Bacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
REGS1_k127_7196015_28	404380.Gbem_1627	1.32e-41	170.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	Cu-binding_MopE,Sulfatase
REGS1_k127_7218738_1	536227.CcarbDRAFT_4777	3.712e-37	141.0	COG2872@1|root,COG2872@2|Bacteria,1UHS6@1239|Firmicutes,24AK0@186801|Clostridia,36GRN@31979|Clostridiaceae	186801|Clostridia	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
REGS1_k127_7218738_2	335543.Sfum_2035	2.748e-05	51.0	COG1716@1|root,COG1716@2|Bacteria,1RGIT@1224|Proteobacteria,43BCI@68525|delta/epsilon subdivisions,2WQHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Clostripain family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C11
REGS1_k127_7218738_0	926550.CLDAP_10690	4.162e-138	450.0	COG3552@1|root,COG4372@1|root,COG3552@2|Bacteria,COG4372@2|Bacteria,2G60I@200795|Chloroflexi	200795|Chloroflexi	S	PFAM VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
REGS1_k127_7221504_1	330214.NIDE3296	4.237e-229	714.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
REGS1_k127_7221504_3	330214.NIDE3299	6.055e-129	419.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	40117|Nitrospirae	S	Evidence 4 Homologs of previously reported genes of	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase
REGS1_k127_7221504_2	330214.NIDE3300	1.692e-135	437.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_7221504_0	330214.NIDE3303	1.28e-301	933.0	COG1271@1|root,COG1271@2|Bacteria	2|Bacteria	C	aerobic electron transport chain	-	-	1.10.3.14	ko:K00425,ko:K08738	ko00190,ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00190,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00153,M00595	R10151,R11325	RC00061,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3,3.D.4.6	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
REGS1_k127_7246337_8	926550.CLDAP_05970	3.421e-48	175.0	COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi	200795|Chloroflexi	C	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_7246337_7	357808.RoseRS_2299	1.868e-48	183.0	COG2086@1|root,COG2086@2|Bacteria,2G6YY@200795|Chloroflexi,374W0@32061|Chloroflexia	32061|Chloroflexia	C	PFAM Electron transfer flavoprotein alpha beta-subunit	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
REGS1_k127_7246337_5	1449126.JQKL01000011_gene3577	4.001e-64	233.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia	186801|Clostridia	C	electron transfer flavoprotein	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4,Fer4_6,Fer4_7
REGS1_k127_7246337_14	1191523.MROS_1344	3.442e-22	98.0	COG1278@1|root,COG1278@2|Bacteria	2|Bacteria	K	Cold shock	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD,DUF1294
REGS1_k127_7246337_11	525904.Tter_0400	8.356e-40	157.0	COG0613@1|root,COG0613@2|Bacteria	2|Bacteria	Q	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	Glyco_trans_1_4,Glyco_transf_4,PHP,PHP_C
REGS1_k127_7246337_2	314265.R2601_24979	4.53e-88	301.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,2TUKT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
REGS1_k127_7246337_12	391603.FBALC1_14667	7.014e-38	149.0	COG5580@1|root,COG5580@2|Bacteria,4PK53@976|Bacteroidetes,1I3SX@117743|Flavobacteriia	976|Bacteroidetes	O	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
REGS1_k127_7246337_4	1121405.dsmv_0026	1.611e-64	226.0	COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,42RKY@68525|delta/epsilon subdivisions,2WNSM@28221|Deltaproteobacteria,2MJZR@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_7246337_6	926569.ANT_15950	1.251e-56	209.0	COG1608@1|root,COG1608@2|Bacteria,2G6TH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM aspartate glutamate uridylate kinase	-	-	2.7.4.26	ko:K06981	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R10093	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
REGS1_k127_7246337_0	926569.ANT_16290	1.13e-303	943.0	COG2759@1|root,COG2759@2|Bacteria,2G5QS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the formate--tetrahydrofolate ligase family	fhs	GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.5.1.5,3.5.4.9,6.3.4.3	ko:K00288,ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00141,M00377	R00943,R01220,R01655	RC00026,RC00111,RC00202,RC00578	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FTHFS
REGS1_k127_7246337_13	926569.ANT_05600	2.059e-31	140.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7246337_1	357808.RoseRS_3083	4.218e-155	503.0	COG0154@1|root,COG0154@2|Bacteria,2G7S4@200795|Chloroflexi,377YI@32061|Chloroflexia	32061|Chloroflexia	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
REGS1_k127_7246337_9	330214.NIDE4175	4.307e-41	171.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_7246337_10	330214.NIDE4175	5.307e-41	169.0	COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae	2|Bacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_7255277_0	457570.Nther_2059	3.65e-49	201.0	COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
REGS1_k127_7261290_0	926569.ANT_22520	5.933e-205	655.0	COG1032@1|root,COG1032@2|Bacteria,2G5N0@200795|Chloroflexi	200795|Chloroflexi	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_7261290_1	1173026.Glo7428_4685	4.54e-64	237.0	COG1664@1|root,COG1664@2|Bacteria,1G2TI@1117|Cyanobacteria	1117|Cyanobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_7261290_2	935557.ATYB01000009_gene951	4.168e-52	192.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2TV3A@28211|Alphaproteobacteria,4B8GB@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_7261290_3	926569.ANT_19350	1.52e-41	167.0	COG0642@1|root,COG3283@1|root,COG2205@2|Bacteria,COG3283@2|Bacteria	2|Bacteria	EK	Transcriptional regulator of aromatic amino acids metabolism	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	ANTAR,GAF_2,GGDEF,HATPase_c,HD_5,HisKA,LytTR,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_7261290_4	1379698.RBG1_1C00001G0857	2.306e-20	98.0	COG5557@1|root,COG5557@2|Bacteria,2NNNQ@2323|unclassified Bacteria	1379698.RBG1_1C00001G0857|-	C	Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7269804_0	1033739.CAEU01000006_gene1303	1.344e-55	199.0	COG0281@1|root,COG0281@2|Bacteria,1UYHB@1239|Firmicutes,4HDRG@91061|Bacilli,26EGN@186818|Planococcaceae	91061|Bacilli	C	Malic enzyme, N-terminal domain	mleA	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh_C,ACT_4,Malic_M,THF_DHG_CYH_C,malic
REGS1_k127_7269804_1	1449126.JQKL01000014_gene3022	5.496e-45	175.0	COG1307@1|root,COG1307@2|Bacteria,1TYCV@1239|Firmicutes,248JV@186801|Clostridia	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
REGS1_k127_7269804_2	1089548.KI783301_gene3216	0.0001212	48.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3WEVF@539002|Bacillales incertae sedis	91061|Bacilli	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
REGS1_k127_7284342_9	251221.35211967	1.025e-23	102.0	COG1177@1|root,COG1177@2|Bacteria,1G1B6@1117|Cyanobacteria	1117|Cyanobacteria	P	ABC-type spermidine putrescine transport system, permease component II	potC	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
REGS1_k127_7284342_5	1183438.GKIL_1130	1.895e-128	424.0	COG0687@1|root,COG0687@2|Bacteria,1G0DM@1117|Cyanobacteria	1117|Cyanobacteria	E	Extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_8
REGS1_k127_7284342_7	43759.JNWK01000020_gene7372	2.014e-81	280.0	COG0388@1|root,COG0388@2|Bacteria,2GP6F@201174|Actinobacteria	201174|Actinobacteria	S	Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
REGS1_k127_7284342_8	926550.CLDAP_37590	8.491e-46	171.0	COG1522@1|root,COG1522@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	asnC	-	-	ko:K03718,ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_AsnC-type
REGS1_k127_7284342_3	1121422.AUMW01000006_gene704	3.417e-163	528.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,26029@186807|Peptococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
REGS1_k127_7284342_1	1121324.CLIT_8c01210	6.551e-183	591.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,25U26@186804|Peptostreptococcaceae	186801|Clostridia	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
REGS1_k127_7284342_4	357808.RoseRS_3926	8.18e-162	520.0	COG0160@1|root,COG0160@2|Bacteria,2G5SK@200795|Chloroflexi,377Z7@32061|Chloroflexia	32061|Chloroflexia	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_7284342_2	868595.Desca_2486	1.187e-171	556.0	COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,2604P@186807|Peptococcaceae	186801|Clostridia	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
REGS1_k127_7284342_10	867903.ThesuDRAFT_02035	1.343e-13	81.0	COG1388@1|root,COG1388@2|Bacteria,1V10C@1239|Firmicutes,25PSQ@186801|Clostridia,3WDR3@538999|Clostridiales incertae sedis	186801|Clostridia	M	TIGRFAM spore coat assembly protein SafA	-	-	-	-	-	-	-	-	-	-	-	-	LysM
REGS1_k127_7284342_0	497964.CfE428DRAFT_0631	4.469e-191	629.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
REGS1_k127_7284342_6	1396418.BATQ01000184_gene2632	1.658e-102	345.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia	74201|Verrucomicrobia	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,NB-ARC
REGS1_k127_7290038_0	324602.Caur_2783	9.284e-79	274.0	COG0601@1|root,COG0601@2|Bacteria,2G662@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_7290038_1	269799.Gmet_1236	1.315e-74	261.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,43TPC@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
REGS1_k127_7290038_3	926569.ANT_30170	9.048e-56	205.0	COG0705@1|root,COG0705@2|Bacteria,2G7BZ@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Rhomboid family protein	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
REGS1_k127_7290038_2	926569.ANT_30180	3.593e-66	231.0	COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi	200795|Chloroflexi	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
REGS1_k127_7290038_4	926569.ANT_30190	1.793e-36	140.0	COG5319@1|root,COG5319@2|Bacteria,2GA9G@200795|Chloroflexi	200795|Chloroflexi	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
REGS1_k127_7303121_1	926569.ANT_06070	9.328e-101	336.0	COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
REGS1_k127_7303121_2	926569.ANT_03710	7.748e-39	153.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	2.1.1.334	ko:K21310	ko00920,map00920	-	R11546	RC02653	ko00000,ko00001,ko01000	-	-	-	NnrU,PEMT
REGS1_k127_7303121_0	926569.ANT_06210	3.13e-181	588.0	COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi	200795|Chloroflexi	V	PFAM VanW family protein	-	-	-	-	-	-	-	-	-	-	-	-	G5,PG_binding_4,VanW
REGS1_k127_7305406_1	234267.Acid_1495	1.507e-65	228.0	COG1131@1|root,COG1131@2|Bacteria,3Y7MA@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_7305406_0	234267.Acid_1494	1.1e-142	465.0	COG0842@1|root,COG1511@1|root,COG0842@2|Bacteria,COG1511@2|Bacteria,3Y8AT@57723|Acidobacteria	57723|Acidobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
REGS1_k127_7305406_2	1207063.P24_15876	7.894e-28	114.0	COG3093@1|root,COG3093@2|Bacteria,1N6H7@1224|Proteobacteria,2UBSK@28211|Alphaproteobacteria,2JXFQ@204441|Rhodospirillales	204441|Rhodospirillales	K	Helix-turn-helix	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
REGS1_k127_7305406_3	107635.AZUO01000001_gene2016	1.947e-27	113.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,2UD9W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Plasmid maintenance system killer	-	-	-	-	-	-	-	-	-	-	-	-	HigB-like_toxin
REGS1_k127_7305406_4	1226325.HMPREF1548_02797	5.495e-13	71.0	COG1309@1|root,COG1309@2|Bacteria,1TWE4@1239|Firmicutes,24C3H@186801|Clostridia,36DCK@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_7305924_1	1193181.BN10_140045	1.468e-16	85.0	COG1266@1|root,COG1266@2|Bacteria,2IGUR@201174|Actinobacteria,4FJ7Y@85021|Intrasporangiaceae	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
REGS1_k127_7305924_0	649831.L083_2698	3.66e-93	325.0	COG0596@1|root,COG0596@2|Bacteria,2GNK7@201174|Actinobacteria,4DHG1@85008|Micromonosporales	201174|Actinobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
REGS1_k127_7305924_2	397291.C804_01856	2.228e-09	68.0	COG2197@1|root,COG2197@2|Bacteria,1V0AE@1239|Firmicutes,24UWD@186801|Clostridia,27PP8@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
REGS1_k127_7317212_0	204669.Acid345_0265	2.113e-73	249.0	COG1028@1|root,COG1028@2|Bacteria,3Y3YM@57723|Acidobacteria,2JI6U@204432|Acidobacteriia	204432|Acidobacteriia	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_7317212_1	588596.U9TBB0	3.965e-27	126.0	COG0790@1|root,KOG1550@2759|Eukaryota	588596.U9TBB0|-	T	ERAD pathway	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7336472_3	926569.ANT_15730	1.268e-69	246.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
REGS1_k127_7336472_6	926569.ANT_15740	4.789e-36	148.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
REGS1_k127_7336472_5	926569.ANT_19230	1.351e-47	183.0	COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi	200795|Chloroflexi	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
REGS1_k127_7336472_2	485913.Krac_12461	6.683e-90	308.0	COG2355@1|root,COG2355@2|Bacteria,2G6FQ@200795|Chloroflexi	200795|Chloroflexi	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
REGS1_k127_7336472_1	1128421.JAGA01000002_gene455	1.431e-98	340.0	COG0539@1|root,COG0539@2|Bacteria,2NNTP@2323|unclassified Bacteria	2|Bacteria	J	Ribosomal protein S1	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
REGS1_k127_7336472_0	1128421.JAGA01000003_gene3520	9.18e-122	405.0	COG1239@1|root,COG1239@2|Bacteria	2|Bacteria	H	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX	chlI	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase
REGS1_k127_734561_8	926569.ANT_23510	6.101e-12	72.0	COG1470@1|root,COG1470@2|Bacteria,2G6XR@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF3048) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
REGS1_k127_734561_7	886293.Sinac_4680	6.674e-19	101.0	COG4932@1|root,COG4932@2|Bacteria,2IYDU@203682|Planctomycetes	203682|Planctomycetes	M	Cna B domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SdrD_B
REGS1_k127_734561_9	333138.LQ50_23125	0.0009107	52.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,4HBPI@91061|Bacilli,1ZB6W@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
REGS1_k127_734561_2	1379698.RBG1_1C00001G1459	4.915e-125	412.0	COG0183@1|root,COG0183@2|Bacteria,2NNU9@2323|unclassified Bacteria	2|Bacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_734561_6	1379698.RBG1_1C00001G1071	1.904e-47	175.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_734561_3	1430331.EP10_13765	1.205e-100	336.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,4HA59@91061|Bacilli,1WFG8@129337|Geobacillus	91061|Bacilli	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	mmgB	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
REGS1_k127_734561_1	1128421.JAGA01000002_gene1517	6.248e-145	476.0	COG3844@1|root,COG3844@2|Bacteria,2NS52@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class-V	kynU	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	3.7.1.3	ko:K01556	ko00380,ko01100,map00380,map01100	M00038	R00987,R02668,R03936	RC00284,RC00415	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
REGS1_k127_734561_0	765420.OSCT_2101	1.791e-210	668.0	COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi	200795|Chloroflexi	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
REGS1_k127_734561_4	1198452.Jab_2c25790	5.542e-77	265.0	COG0789@1|root,COG0789@2|Bacteria,1REB7@1224|Proteobacteria,2WEJ4@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
REGS1_k127_734561_5	926569.ANT_18630	1.366e-58	210.0	COG0564@1|root,COG0564@2|Bacteria,2G68N@200795|Chloroflexi	200795|Chloroflexi	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
REGS1_k127_7373163_0	1121405.dsmv_3003	0.0	2749.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_7373163_1	306281.AJLK01000173_gene5122	6.538e-16	79.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1JHSH@1189|Stigonemataceae	1117|Cyanobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
REGS1_k127_7403675_3	261292.Nit79A3_0025	1.5e-08	60.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2VUCR@28216|Betaproteobacteria,373FR@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM transport-associated	-	-	-	ko:K04065	-	-	-	-	ko00000	-	-	-	BON
REGS1_k127_7403675_2	768671.ThimaDRAFT_0514	1.761e-17	85.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,1SCQ6@1236|Gammaproteobacteria,1WZ8U@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
REGS1_k127_7403675_1	204773.HEAR2524	2.161e-28	117.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2VW2V@28216|Betaproteobacteria,4750Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
REGS1_k127_7403675_0	1390370.O203_19200	2.986e-29	125.0	COG1873@1|root,COG1873@2|Bacteria,1QTWZ@1224|Proteobacteria,1SABC@1236|Gammaproteobacteria,1YJS8@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	PRC-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	PRC
REGS1_k127_7407429_0	926569.ANT_21050	4.167e-228	714.0	COG0402@1|root,COG1437@1|root,COG0402@2|Bacteria,COG1437@2|Bacteria,2G6DG@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine	mtaD	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,CYTH
REGS1_k127_7407429_1	1283287.KB822583_gene2790	5.637e-18	96.0	COG2866@1|root,COG2866@2|Bacteria	2|Bacteria	E	metallocarboxypeptidase activity	-	-	-	ko:K14054	-	-	-	-	ko00000	-	-	-	Peptidase_M14
REGS1_k127_7413971_2	926569.ANT_09930	1.431e-73	256.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
REGS1_k127_7413971_1	926569.ANT_09920	9.71e-91	309.0	COG1131@1|root,COG1131@2|Bacteria,2G890@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_7413971_0	926569.ANT_09910	2.587e-95	321.0	COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi	200795|Chloroflexi	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
REGS1_k127_7413971_3	926569.ANT_09900	1.045e-53	195.0	COG0558@1|root,COG0558@2|Bacteria,2G6ZT@200795|Chloroflexi	200795|Chloroflexi	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_7413971_4	926569.ANT_09890	2.027e-49	179.0	COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi	200795|Chloroflexi	D	PFAM cell divisionFtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
REGS1_k127_7420271_0	1005058.UMN179_02020	1.82e-111	368.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,1RNEB@1236|Gammaproteobacteria,1Y87V@135625|Pasteurellales	135625|Pasteurellales	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
REGS1_k127_7420271_5	926569.ANT_01630	1.252e-26	115.0	2CMS6@1|root,339SN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_7420271_1	1128421.JAGA01000003_gene2893	2.233e-101	337.0	COG0730@1|root,COG0730@2|Bacteria,2NP64@2323|unclassified Bacteria	2|Bacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
REGS1_k127_7420271_2	926550.CLDAP_13470	1.118e-43	166.0	COG2087@1|root,COG2087@2|Bacteria,2G6SV@200795|Chloroflexi	200795|Chloroflexi	H	PFAM cobalbumin biosynthesis protein	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
REGS1_k127_7420271_4	1121428.DESHY_80044___1	9.572e-39	158.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24JDV@186801|Clostridia,261XP@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	pspA	-	3.1.3.3,3.1.3.73	ko:K02226,ko:K22305	ko00260,ko00680,ko00860,ko01100,ko01120,ko01130,map00260,map00680,map00860,map01100,map01120,map01130	M00122	R00582,R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
REGS1_k127_7420271_3	266117.Rxyl_0648	3.912e-40	158.0	COG0368@1|root,COG0368@2|Bacteria,2HP52@201174|Actinobacteria,4CQGW@84995|Rubrobacteria	84995|Rubrobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
REGS1_k127_7420271_6	983920.Y88_3427	4.365e-12	66.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,2TT92@28211|Alphaproteobacteria,2K227@204457|Sphingomonadales	204457|Sphingomonadales	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
REGS1_k127_7431649_0	926569.ANT_27830	1.663e-53	196.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
REGS1_k127_7431649_1	1033743.CAES01000085_gene2957	5.184e-33	147.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_17_28,CBM_2,CBM_3,CBM_6,Cellulase,F5_F8_type_C,Glyco_hydro_26,Glyco_hydro_8
REGS1_k127_7437214_0	330214.NIDE4097	4.379e-101	332.0	COG2804@1|root,COG2804@2|Bacteria,3J0XR@40117|Nitrospirae	40117|Nitrospirae	NU	Type II/IV secretion system protein	-	-	-	ko:K02454,ko:K02652	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
REGS1_k127_7437214_1	640511.BC1002_5732	7.797e-83	281.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,1K4KX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
REGS1_k127_7437214_2	640511.BC1002_5732	2.443e-38	150.0	COG2826@1|root,COG2826@2|Bacteria,1PP49@1224|Proteobacteria,2VI0E@28216|Betaproteobacteria,1K4KX@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
REGS1_k127_746509_1	1454004.AW11_02454	3.166e-51	204.0	COG2203@1|root,COG3437@1|root,COG4585@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2WIB4@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
REGS1_k127_746509_0	243164.DET1063	6.276e-53	194.0	COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi,34CR4@301297|Dehalococcoidia	301297|Dehalococcoidia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_7499256_2	263358.VAB18032_19430	9.499e-13	70.0	COG1175@1|root,COG1175@2|Bacteria,2GJZD@201174|Actinobacteria,4DE1N@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
REGS1_k127_7499256_0	28444.JODQ01000014_gene6633	1.26e-157	512.0	COG1653@1|root,COG1653@2|Bacteria,2GP9H@201174|Actinobacteria,4EK1W@85012|Streptosporangiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
REGS1_k127_7499256_1	926550.CLDAP_26530	2.22e-57	207.0	COG1609@1|root,COG1609@2|Bacteria,2G8C1@200795|Chloroflexi	200795|Chloroflexi	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
REGS1_k127_7537967_10	926569.ANT_29740	1.9e-13	81.0	COG1744@1|root,COG1744@2|Bacteria	2|Bacteria	ET	ABC transporter substrate-binding protein PnrA-like	med	-	-	ko:K02058,ko:K05519,ko:K07335	-	M00221	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1.2	-	-	Bmp
REGS1_k127_7537967_11	504728.K649_08035	2.389e-12	73.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
REGS1_k127_7537967_3	926569.ANT_29790	2.602e-75	259.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
REGS1_k127_7537967_9	1457250.BBMO01000001_gene1664	1.59e-27	125.0	COG1028@1|root,arCOG01259@2157|Archaea,2XYCI@28890|Euryarchaeota,23WAX@183963|Halobacteria	183963|Halobacteria	I	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
REGS1_k127_7537967_6	926569.ANT_03650	8.681e-46	171.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	-	R02029,R05627	RC00002,RC00017	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
REGS1_k127_7537967_4	926569.ANT_03640	3.313e-65	235.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.77	ko:K03752,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
REGS1_k127_7537967_0	926569.ANT_03630	8.143e-110	363.0	COG5322@1|root,COG5322@2|Bacteria,2G8N0@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Shikimate quinate 5-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Shikimate_DH
REGS1_k127_7537967_2	926569.ANT_19370	3.82e-87	299.0	COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi	200795|Chloroflexi	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
REGS1_k127_7537967_1	383372.Rcas_3156	1.413e-89	307.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7537967_7	204669.Acid345_2035	5.781e-43	171.0	COG1734@1|root,COG2208@1|root,COG1734@2|Bacteria,COG2208@2|Bacteria,3Y4RV@57723|Acidobacteria	57723|Acidobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
REGS1_k127_7537967_8	1121015.N789_03735	2.421e-35	136.0	COG1834@1|root,COG1834@2|Bacteria,1MZ9U@1224|Proteobacteria,1RN0M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Amidinotransferase	-	-	3.5.3.18	ko:K01482	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	Amidinotransf
REGS1_k127_7572870_2	1128421.JAGA01000003_gene3536	4.934e-35	142.0	COG5002@1|root,COG5002@2|Bacteria,2NS5D@2323|unclassified Bacteria	2|Bacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K02484,ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_7572870_0	1128421.JAGA01000003_gene3537	1e-90	304.0	COG0745@1|root,COG0745@2|Bacteria,2NPCK@2323|unclassified Bacteria	2|Bacteria	T	Two component transcriptional regulator, winged helix family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_7572870_1	926569.ANT_07930	9.615e-67	232.0	COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_7585097_1	246194.CHY_0618	5.691e-73	254.0	COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,249N1@186801|Clostridia,42ETF@68295|Thermoanaerobacterales	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_7585097_2	290315.Clim_1144	1.394e-68	236.0	COG1803@1|root,COG1803@2|Bacteria	2|Bacteria	G	methylglyoxal synthase activity	mgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	iECUMN_1333.ECUMN_1153,iYL1228.KPN_00992	MGS
REGS1_k127_7585097_3	304371.MCP_0795	1.312e-59	211.0	COG4430@1|root,arCOG10241@2157|Archaea,2XUJA@28890|Euryarchaeota	28890|Euryarchaeota	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
REGS1_k127_7585097_0	926569.ANT_20420	2.772e-315	982.0	COG1197@1|root,COG1197@2|Bacteria,2G5UW@200795|Chloroflexi	200795|Chloroflexi	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
REGS1_k127_7593354_0	330214.NIDE2980	6.084e-137	443.0	COG1830@1|root,COG1830@2|Bacteria,3J1DE@40117|Nitrospirae	40117|Nitrospirae	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
REGS1_k127_7593354_1	1123508.JH636456_gene143	1.759e-129	417.0	COG0033@1|root,COG0033@2|Bacteria,2IYG0@203682|Planctomycetes	203682|Planctomycetes	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_7593651_5	264732.Moth_1824	5.571e-17	89.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,42GJ7@68295|Thermoanaerobacterales	186801|Clostridia	P	TIGRFAM molybdenum ABC transporter, periplasmic	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
REGS1_k127_7593651_0	926569.ANT_04250	2.839e-274	858.0	COG0303@1|root,COG1910@1|root,COG0303@2|Bacteria,COG1910@2|Bacteria,2G64H@200795|Chloroflexi	200795|Chloroflexi	K	PBP superfamily domain	-	-	2.10.1.1	ko:K03750,ko:K07219	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	HTH_3,MoCF_biosynth,MoeA_C,MoeA_N,PBP_like
REGS1_k127_7593651_3	926569.ANT_04260	1.716e-63	225.0	COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi	200795|Chloroflexi	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_7593651_4	290397.Adeh_2275	2.568e-61	224.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,43AKU@68525|delta/epsilon subdivisions,2X60W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome C oxidase subunit II, transmembrane domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
REGS1_k127_7593651_1	926569.ANT_05300	6.231e-271	845.0	COG0843@1|root,COG0843@2|Bacteria,2G5XS@200795|Chloroflexi	200795|Chloroflexi	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
REGS1_k127_7593651_2	926569.ANT_05280	2.315e-68	242.0	COG1845@1|root,COG1845@2|Bacteria,2G74U@200795|Chloroflexi	200795|Chloroflexi	C	PFAM cytochrome c oxidase, subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
REGS1_k127_760878_3	1384484.AEQU_0667	2.137e-23	115.0	COG1807@1|root,COG1807@2|Bacteria,2GNXR@201174|Actinobacteria,4CVAP@84998|Coriobacteriia	84998|Coriobacteriia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_760878_7	1232410.KI421418_gene2357	8.762e-06	55.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_760878_0	1232437.KL661971_gene4894	2.399e-105	351.0	COG2423@1|root,COG2423@2|Bacteria,1MWH6@1224|Proteobacteria,42SUF@68525|delta/epsilon subdivisions,2WPJU@28221|Deltaproteobacteria,2MKU8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	1.4.1.1,4.3.1.12	ko:K01750,ko:K19244	ko00250,ko00330,ko00430,ko01100,ko01110,ko01130,ko01230,map00250,map00330,map00430,map01100,map01110,map01130,map01230	-	R00396,R00671	RC00008,RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
REGS1_k127_760878_5	765912.Thimo_2729	6.073e-10	68.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin,Rubrerythrin
REGS1_k127_760878_2	1499967.BAYZ01000120_gene3420	6.81e-60	217.0	COG2020@1|root,COG2020@2|Bacteria,2NR07@2323|unclassified Bacteria	2|Bacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_760878_1	1094508.Tsac_0271	8.7e-73	261.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia,42GDT@68295|Thermoanaerobacterales	186801|Clostridia	GK	pfam rok	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
REGS1_k127_760878_6	744872.Spica_2009	1.196e-07	57.0	COG4213@1|root,COG4213@2|Bacteria,2J5BZ@203691|Spirochaetes	203691|Spirochaetes	G	ABC-type xylose transport system, periplasmic component	-	-	-	ko:K10543,ko:K10546	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	Peripla_BP_4
REGS1_k127_7616252_4	378806.STAUR_6805	1.071e-35	142.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
REGS1_k127_7616252_3	324602.Caur_1725	9.272e-47	177.0	COG1075@1|root,COG1075@2|Bacteria	2|Bacteria	KLT	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,PGAP1
REGS1_k127_7616252_2	1229172.JQFA01000004_gene1792	3.442e-47	185.0	COG0451@1|root,COG0451@2|Bacteria,1G2DP@1117|Cyanobacteria,1H9EI@1150|Oscillatoriales	1117|Cyanobacteria	M	epimerase dehydratase	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
REGS1_k127_7616252_0	926569.ANT_26430	9.911e-224	722.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2G6IW@200795|Chloroflexi	200795|Chloroflexi	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_7616252_1	333138.LQ50_20840	3.884e-108	371.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HACS@91061|Bacilli,1ZATG@1386|Bacillus	91061|Bacilli	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
REGS1_k127_7616252_7	710685.MycrhN_4530	4.143e-09	69.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,232ZS@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyltransferase	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_7616252_6	888832.HMPREF9420_1700	1.618e-11	68.0	COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,2FTWG@200643|Bacteroidia	976|Bacteroidetes	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_7616252_8	398578.Daci_4515	0.0002394	53.0	COG0823@1|root,COG0841@1|root,COG1361@1|root,COG1572@1|root,COG1657@1|root,COG4733@1|root,COG0823@2|Bacteria,COG0841@2|Bacteria,COG1361@2|Bacteria,COG1572@2|Bacteria,COG1657@2|Bacteria,COG4733@2|Bacteria,1QVSF@1224|Proteobacteria	1224|Proteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,DUF11,DUF1566,Laminin_G_3,OmpA,OmpA_membrane,TIG
REGS1_k127_7616252_5	1206101.AZXC01000005_gene2844	2.085e-14	85.0	COG4188@1|root,COG4188@2|Bacteria,2I6N2@201174|Actinobacteria	201174|Actinobacteria	S	Chlorophyllase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2
REGS1_k127_7634039_1	926569.ANT_08710	2.872e-195	628.0	COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi	200795|Chloroflexi	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
REGS1_k127_7634039_0	926569.ANT_08730	0.0	1056.0	COG0751@1|root,COG0752@1|root,COG0751@2|Bacteria,COG0752@2|Bacteria,2G7V0@200795|Chloroflexi	200795|Chloroflexi	J	Glycyl-tRNA synthetase alpha subunit	glyQS	-	6.1.1.14	ko:K14164	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	tRNA-synt_2e,tRNA_synt_2f
REGS1_k127_7662483_8	926569.ANT_16630	4.765e-16	78.0	COG0820@1|root,COG0820@2|Bacteria,2G5SD@200795|Chloroflexi	200795|Chloroflexi	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
REGS1_k127_7662483_0	926569.ANT_12980	3.06e-322	1024.0	COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi	200795|Chloroflexi	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	NHL,PMT_2
REGS1_k127_7662483_1	926569.ANT_20580	4.349e-173	550.0	COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi	200795|Chloroflexi	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
REGS1_k127_7662483_2	926569.ANT_20570	1.04e-148	474.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi	200795|Chloroflexi	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
REGS1_k127_7662483_6	1408254.T458_16740	6.282e-24	102.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,26YZG@186822|Paenibacillaceae	91061|Bacilli	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_7662483_3	926569.ANT_20510	7.048e-129	420.0	COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi	200795|Chloroflexi	H	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
REGS1_k127_7662483_7	926569.ANT_25930	2.232e-18	96.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,VanY,YkuD
REGS1_k127_7662483_5	666685.R2APBS1_1319	1.078e-60	216.0	COG0637@1|root,COG0637@2|Bacteria,1QXCM@1224|Proteobacteria,1T47N@1236|Gammaproteobacteria,1X62V@135614|Xanthomonadales	135614|Xanthomonadales	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_7662483_4	926569.ANT_20520	5.671e-82	286.0	COG0142@1|root,COG0142@2|Bacteria,2G6BM@200795|Chloroflexi	200795|Chloroflexi	H	Belongs to the FPP GGPP synthase family	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_7779079_1	324602.Caur_2786	3.281e-26	119.0	COG1802@1|root,COG1802@2|Bacteria,2G993@200795|Chloroflexi,377MM@32061|Chloroflexia	32061|Chloroflexia	K	PFAM regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
REGS1_k127_7779079_0	1089553.Tph_c27670	1.916e-58	209.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,42FJI@68295|Thermoanaerobacterales	186801|Clostridia	S	Methionine synthase B12-binding module cap domain protein	-	-	2.1.1.13	ko:K00548,ko:K14084	ko00270,ko00450,ko00670,ko00680,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00680,map01100,map01110,map01120,map01200,map01230	M00017,M00563	R00946,R09124,R09365	RC00035,RC00113,RC00732,RC01241,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2
REGS1_k127_7779079_2	1408428.JNJP01000007_gene1900	1.641e-07	56.0	COG5598@1|root,COG5598@2|Bacteria,1MWJN@1224|Proteobacteria,42N1X@68525|delta/epsilon subdivisions,2WKMS@28221|Deltaproteobacteria,2MG0M@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
REGS1_k127_7794763_1	765420.OSCT_2981	2.654e-70	242.0	COG0039@1|root,COG0039@2|Bacteria,2G61S@200795|Chloroflexi,374VR@32061|Chloroflexia	32061|Chloroflexia	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
REGS1_k127_7794763_0	880073.Calab_0927	1.446e-165	533.0	COG0372@1|root,COG0372@2|Bacteria,2NP9P@2323|unclassified Bacteria	2|Bacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
REGS1_k127_7794763_2	926569.ANT_06510	1.992e-68	252.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	PMT_2
REGS1_k127_779600_10	644968.DFW101_2098	4.749e-16	89.0	COG2230@1|root,COG2230@2|Bacteria,1NKE6@1224|Proteobacteria,432ND@68525|delta/epsilon subdivisions,2WXTJ@28221|Deltaproteobacteria,2M8K4@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
REGS1_k127_779600_1	631362.Thi970DRAFT_02821	5.52e-174	561.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria,1QR54@1224|Proteobacteria,1SMRM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	MQ	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_779600_9	926569.ANT_06280	9.084e-55	196.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	DUF4388,HTH_24,MarR_2
REGS1_k127_779600_4	326427.Cagg_1543	1.294e-124	408.0	COG0451@1|root,COG0451@2|Bacteria,2GBWQ@200795|Chloroflexi,3774S@32061|Chloroflexia	32061|Chloroflexia	M	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_779600_3	926569.ANT_06290	1.902e-149	478.0	COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi	200795|Chloroflexi	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
REGS1_k127_779600_6	234267.Acid_4640	4.093e-111	365.0	COG1682@1|root,COG1682@2|Bacteria,3Y7JV@57723|Acidobacteria	57723|Acidobacteria	GM	ABC-2 type transporter	-	-	-	ko:K09690	ko02010,map02010	M00250	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.103	-	-	ABC2_membrane
REGS1_k127_779600_0	926569.ANT_06310	1.443e-187	594.0	COG1134@1|root,COG1134@2|Bacteria	2|Bacteria	GM	teichoic acid transport	-	-	3.6.3.38	ko:K01990,ko:K09689,ko:K09691	ko02010,map02010	M00249,M00250,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.101,3.A.1.103	-	-	ABC_tran,Wzt_C
REGS1_k127_779600_2	926569.ANT_06320	1.743e-165	535.0	COG0763@1|root,COG0763@2|Bacteria	2|Bacteria	M	lipid-A-disaccharide synthase activity	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	Capsule_synth
REGS1_k127_779600_7	926569.ANT_06330	2.19e-94	317.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
REGS1_k127_779600_5	926569.ANT_06340	2.019e-117	382.0	COG1086@1|root,COG1086@2|Bacteria,2G8BP@200795|Chloroflexi	200795|Chloroflexi	M	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt_2
REGS1_k127_782143_1	1449347.JQLN01000005_gene5455	6.089e-13	78.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria,2M5FE@2063|Kitasatospora	201174|Actinobacteria	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
REGS1_k127_782143_0	463191.SSEG_04317	3.251e-25	117.0	COG4932@1|root,COG4932@2|Bacteria,2GJ4T@201174|Actinobacteria	201174|Actinobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3494
REGS1_k127_783326_1	639030.JHVA01000001_gene134	2.772e-36	139.0	COG0380@1|root,COG0380@2|Bacteria,3Y3X7@57723|Acidobacteria,2JKGZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyltransferase family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_20
REGS1_k127_783326_0	639030.JHVA01000001_gene134	3.515e-176	560.0	COG0380@1|root,COG0380@2|Bacteria,3Y3X7@57723|Acidobacteria,2JKGZ@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyltransferase family 20	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_20
REGS1_k127_783326_4	883126.HMPREF9710_03752	1.735e-09	64.0	COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria,2VXPK@28216|Betaproteobacteria,4755V@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
REGS1_k127_783326_2	96561.Dole_2317	5.425e-18	85.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_783326_3	583355.Caka_1453	9.311e-10	59.0	COG2197@1|root,COG2197@2|Bacteria,46T2B@74201|Verrucomicrobia,3K7X9@414999|Opitutae	414999|Opitutae	K	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_7853343_4	926569.ANT_09480	2.334e-115	383.0	COG0237@1|root,COG0237@2|Bacteria,2G6RQ@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
REGS1_k127_7853343_6	926569.ANT_17840	2.969e-28	117.0	COG0375@1|root,COG0375@2|Bacteria,2G7H5@200795|Chloroflexi	200795|Chloroflexi	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
REGS1_k127_7853343_0	926569.ANT_17860	1.692e-261	828.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
REGS1_k127_7853343_7	1463936.JOJI01000024_gene1244	1.242e-26	111.0	COG0298@1|root,COG0298@2|Bacteria,2IMSQ@201174|Actinobacteria	201174|Actinobacteria	O	Hydrogenase expression formation protein	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
REGS1_k127_7853343_3	765420.OSCT_2610	9.796e-118	384.0	COG0409@1|root,COG0409@2|Bacteria,2G5MS@200795|Chloroflexi,376PX@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
REGS1_k127_7853343_5	886293.Sinac_4490	1.056e-36	140.0	COG0409@1|root,COG0409@2|Bacteria,2IYJ2@203682|Planctomycetes	203682|Planctomycetes	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
REGS1_k127_7853343_8	215803.DB30_2188	7.996e-25	118.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
REGS1_k127_7853343_1	926569.ANT_13120	2.3e-180	583.0	COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi	200795|Chloroflexi	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
REGS1_k127_7853343_2	316274.Haur_0632	7.474e-150	482.0	COG0343@1|root,COG0343@2|Bacteria,2G5RE@200795|Chloroflexi,3752Z@32061|Chloroflexia	32061|Chloroflexia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
REGS1_k127_7853343_9	1038859.AXAU01000004_gene4751	1.713e-12	70.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2TSUR@28211|Alphaproteobacteria,3JTTD@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
REGS1_k127_7886748_1	261292.Nit79A3_0034	5.52e-125	404.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,3743H@32003|Nitrosomonadales	28216|Betaproteobacteria	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_7886748_0	1340493.JNIF01000004_gene43	0.0	1414.0	COG0058@1|root,COG0058@2|Bacteria,3Y65H@57723|Acidobacteria	57723|Acidobacteria	G	PFAM glycosyl transferase, family 35	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
REGS1_k127_7886748_3	1123393.KB891326_gene87	1.541e-24	108.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_7886748_2	1340493.JNIF01000004_gene42	1.106e-34	134.0	COG0033@1|root,COG0033@2|Bacteria	2|Bacteria	G	Phosphoglucomutase	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_7946251_1	1242864.D187_007396	7.899e-54	194.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
REGS1_k127_7946251_0	1123376.AUIU01000012_gene1330	1.975e-153	503.0	COG0370@1|root,COG0370@2|Bacteria	2|Bacteria	P	ferrous iron transmembrane transporter activity	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
REGS1_k127_7946251_3	439235.Dalk_1640	8.954e-06	52.0	COG0735@1|root,COG1918@1|root,COG0735@2|Bacteria,COG1918@2|Bacteria,1RDWJ@1224|Proteobacteria,42P61@68525|delta/epsilon subdivisions,2X5PQ@28221|Deltaproteobacteria,2MJ7H@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR,FeoA
REGS1_k127_7946251_2	1280390.CBQR020000092_gene1970	3.667e-06	57.0	COG4346@1|root,COG5650@1|root,COG4346@2|Bacteria,COG5650@2|Bacteria,1TSHX@1239|Firmicutes,4HNW3@91061|Bacilli,27548@186822|Paenibacillaceae	91061|Bacilli	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT_2,PMT_4TMC
REGS1_k127_7991135_2	383372.Rcas_1237	8.836e-52	185.0	COG3842@1|root,COG3842@2|Bacteria,2G5JJ@200795|Chloroflexi,37726@32061|Chloroflexia	32061|Chloroflexia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
REGS1_k127_7991135_1	1192868.CAIU01000011_gene1307	3.685e-79	280.0	COG1177@1|root,COG1177@2|Bacteria,1MV4A@1224|Proteobacteria,2TUA3@28211|Alphaproteobacteria,43IW3@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	ABC-type spermidine putrescine transport system, permease component II	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_7991135_0	926569.ANT_31320	1.047e-115	380.0	COG4132@1|root,COG4132@2|Bacteria,2G69Y@200795|Chloroflexi	200795|Chloroflexi	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_7991135_3	1122132.AQYH01000019_gene342	1.395e-15	78.0	COG1840@1|root,COG1840@2|Bacteria,1Q13Q@1224|Proteobacteria,2TS7Y@28211|Alphaproteobacteria,4B8Z6@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type Fe3 transport system, periplasmic component	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_6
REGS1_k127_8030190_2	926550.CLDAP_32840	1.345e-91	308.0	COG2188@1|root,COG2188@2|Bacteria,2G781@200795|Chloroflexi	200795|Chloroflexi	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_8030190_1	1121481.AUAS01000003_gene3883	1.046e-155	500.0	COG0673@1|root,COG0673@2|Bacteria,4NGHW@976|Bacteroidetes,47XR6@768503|Cytophagia	976|Bacteroidetes	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_8030190_0	1499967.BAYZ01000159_gene503	2.688e-160	518.0	COG2407@1|root,COG2407@2|Bacteria	2|Bacteria	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8030190_3	344747.PM8797T_03174	2.085e-05	49.0	COG0673@1|root,COG0673@2|Bacteria,2IYW6@203682|Planctomycetes	203682|Planctomycetes	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
REGS1_k127_8045329_0	926569.ANT_01830	0.0	1062.0	COG0587@1|root,COG0587@2|Bacteria,2G5IY@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
REGS1_k127_8045329_1	1499967.BAYZ01000033_gene1106	1.96e-73	255.0	COG3382@1|root,COG3382@2|Bacteria	2|Bacteria	J	B3 4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B3_4
REGS1_k127_8085202_3	926569.ANT_10620	2.894e-08	60.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi	200795|Chloroflexi	H	Polynucleotide adenylyltransferase region	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
REGS1_k127_8085202_1	926569.ANT_14050	3.595e-49	182.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
REGS1_k127_8085202_0	926569.ANT_10600	3.505e-234	733.0	COG0442@1|root,COG0442@2|Bacteria,2G636@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
REGS1_k127_8085202_2	497964.CfE428DRAFT_3727	1.192e-30	127.0	2FH6M@1|root,34912@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
REGS1_k127_8085202_4	1382306.JNIM01000001_gene3986	7.376e-08	56.0	COG0619@1|root,COG0619@2|Bacteria,2G8RH@200795|Chloroflexi	200795|Chloroflexi	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
REGS1_k127_8088811_1	224911.27355976	4.61e-99	330.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
REGS1_k127_8088811_4	381666.H16_B0689	4.11e-22	99.0	2E7PS@1|root,3325B@2|Bacteria,1PVAH@1224|Proteobacteria,2VVUK@28216|Betaproteobacteria,1KAP4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8088811_5	1366050.N234_24345	5.078e-16	79.0	2E7PS@1|root,3325B@2|Bacteria,1PVAH@1224|Proteobacteria,2VVUK@28216|Betaproteobacteria,1KAP4@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8088811_2	869210.Marky_1615	2.385e-98	327.0	COG0479@1|root,COG0479@2|Bacteria,1WIEW@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
REGS1_k127_8088811_0	926569.ANT_22150	2.649e-298	924.0	COG1053@1|root,COG1053@2|Bacteria,2G5YB@200795|Chloroflexi	200795|Chloroflexi	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_8088811_6	105420.BBPO01000010_gene2382	0.0001225	49.0	COG2142@1|root,COG2142@2|Bacteria,2GNKE@201174|Actinobacteria,2NI1D@228398|Streptacidiphilus	201174|Actinobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
REGS1_k127_8089036_0	926569.ANT_27450	8.978e-237	768.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2G790@200795|Chloroflexi	200795|Chloroflexi	T	Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,SpoIIE
REGS1_k127_8101228_0	1123023.JIAI01000001_gene7302	5.27e-90	302.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4E12E@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
REGS1_k127_8101228_1	1502851.FG93_00482	5.795e-82	286.0	COG0395@1|root,COG0395@2|Bacteria,1QW7F@1224|Proteobacteria,2TR3V@28211|Alphaproteobacteria,3JSTC@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Binding-protein-dependent transport system inner membrane component	MA20_03695	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
REGS1_k127_8101228_2	402777.KB235903_gene1431	1.497e-81	288.0	COG1653@1|root,COG1653@2|Bacteria,1G04B@1117|Cyanobacteria,1H8YD@1150|Oscillatoriales	1117|Cyanobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
REGS1_k127_8127437_4	985255.APHJ01000027_gene889	5.006e-14	80.0	COG3340@1|root,COG3340@2|Bacteria,4NEXW@976|Bacteroidetes,1HXTK@117743|Flavobacteriia,2P5UJ@244698|Gillisia	976|Bacteroidetes	E	Peptidase family S51	pepE	-	3.4.13.21	ko:K05995	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
REGS1_k127_8127437_5	1536775.H70737_11420	3.68e-05	49.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli,26RI0@186822|Paenibacillaceae	91061|Bacilli	E	generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
REGS1_k127_8127437_3	497964.CfE428DRAFT_6673	2.387e-24	105.0	COG0724@1|root,COG0724@2|Bacteria,46VMU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM RNP-1 like RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
REGS1_k127_8127437_2	926569.ANT_01690	2.237e-74	255.0	COG0125@1|root,COG0125@2|Bacteria,2G6G2@200795|Chloroflexi	200795|Chloroflexi	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
REGS1_k127_8127437_0	479434.Sthe_0612	4.514e-88	304.0	COG0265@1|root,COG0265@2|Bacteria,2G8RK@200795|Chloroflexi,27Y6G@189775|Thermomicrobia	200795|Chloroflexi	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	1.3.1.74,3.4.21.107	ko:K04771,ko:K08070	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_8127437_1	926569.ANT_01680	3.801e-77	265.0	COG3854@1|root,COG3854@2|Bacteria,2G5P5@200795|Chloroflexi	200795|Chloroflexi	S	PFAM single-stranded nucleic acid binding R3H domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_30,R3H
REGS1_k127_8129047_5	326427.Cagg_2787	1.543e-65	233.0	COG0566@1|root,COG0566@2|Bacteria	2|Bacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	spoU	-	2.1.1.185	ko:K03218,ko:K03437	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
REGS1_k127_8129047_8	324602.Caur_2581	2.281e-24	108.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8129047_0	886293.Sinac_2608	8.889e-115	381.0	COG0075@1|root,COG0075@2|Bacteria,2IYEK@203682|Planctomycetes	203682|Planctomycetes	E	Aminotransferase class-V	-	-	2.6.1.44,2.6.1.45,2.6.1.51	ko:K00830	ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	M00346,M00532	R00369,R00372,R00585,R00588	RC00006,RC00008,RC00018	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
REGS1_k127_8129047_4	926569.ANT_03810	1.37e-80	283.0	COG3583@1|root,COG3584@1|root,COG3583@2|Bacteria,COG3584@2|Bacteria,2G8CU@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF348,G5
REGS1_k127_8129047_7	1120985.AUMI01000005_gene2506	1.944e-27	126.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4H30N@909932|Negativicutes	909932|Negativicutes	K	Cell envelope-like function transcriptional attenuator common domain protein	lytR	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
REGS1_k127_8129047_1	926569.ANT_03800	8.519e-89	301.0	COG0030@1|root,COG0030@2|Bacteria,2G6DA@200795|Chloroflexi	200795|Chloroflexi	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
REGS1_k127_8129047_2	926569.ANT_03790	2.38e-88	298.0	COG0463@1|root,COG0463@2|Bacteria,2GBP0@200795|Chloroflexi	200795|Chloroflexi	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
REGS1_k127_8129047_6	926569.ANT_03760	2.132e-52	188.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
REGS1_k127_8129047_3	926569.ANT_06130	6.054e-87	300.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,LysM,YkuD
REGS1_k127_8129406_7	404589.Anae109_3607	3.523e-09	57.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
REGS1_k127_8129406_6	571.MC52_20935	2.291e-23	102.0	COG1977@1|root,COG1977@2|Bacteria,1N15U@1224|Proteobacteria,1SAI1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_8129406_4	525904.Tter_2032	5.274e-34	133.0	COG2041@1|root,COG2041@2|Bacteria	2|Bacteria	V	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
REGS1_k127_8129406_5	545694.TREPR_3714	4.358e-33	132.0	COG1310@1|root,COG1310@2|Bacteria,2JAFD@203691|Spirochaetes	203691|Spirochaetes	S	JAB/MPN domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
REGS1_k127_8129406_1	1303518.CCALI_00534	1.078e-97	330.0	COG0031@1|root,COG0031@2|Bacteria	2|Bacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113,2.5.1.47	ko:K12339,ko:K21148	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122	M00021	R00897,R03132,R03601,R04859,R10610	RC00020,RC02814,RC02821,RC02876,RC03225	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_8129406_0	926569.ANT_14030	3.777e-299	932.0	COG0480@1|root,COG0480@2|Bacteria,2G680@200795|Chloroflexi	200795|Chloroflexi	J	elongation factor Tu domain 2 protein	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_8129406_3	926569.ANT_10650	9.651e-41	158.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.67	ko:K00569	ko00983,map00983	-	R08236,R08239,R08246	RC00003,RC00980,RC02277	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,TPMT
REGS1_k127_8129406_2	926550.CLDAP_34250	7.742e-77	267.0	COG0696@1|root,COG0696@2|Bacteria,2G7GD@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	-	-	-	-	-	-	-	-	-	-	-	-	Metalloenzyme
REGS1_k127_8137586_3	926569.ANT_04340	1.502e-21	99.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	mec	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
REGS1_k127_8137586_1	926569.ANT_04330	4.389e-50	188.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
REGS1_k127_814036_5	518766.Rmar_1606	9.175e-09	56.0	COG0702@1|root,COG0702@2|Bacteria,4NEJF@976|Bacteroidetes,1FIWH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,Epimerase,NAD_binding_10
REGS1_k127_814036_2	926569.ANT_02530	3.597e-84	291.0	COG0614@1|root,COG0614@2|Bacteria,2G6TS@200795|Chloroflexi	200795|Chloroflexi	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
REGS1_k127_814036_0	926569.ANT_02520	4.423e-123	403.0	COG0609@1|root,COG0609@2|Bacteria,2G6E8@200795|Chloroflexi	200795|Chloroflexi	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
REGS1_k127_814036_1	926569.ANT_02510	1.894e-84	287.0	COG1120@1|root,COG1120@2|Bacteria,2G6QS@200795|Chloroflexi	200795|Chloroflexi	P	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
REGS1_k127_814036_3	926550.CLDAP_16570	4.749e-70	242.0	COG2109@1|root,COG2109@2|Bacteria,2G6Q6@200795|Chloroflexi	200795|Chloroflexi	H	PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
REGS1_k127_8145143_3	195250.CM001776_gene2577	4.357e-61	216.0	COG0318@1|root,COG0318@2|Bacteria,1GQE8@1117|Cyanobacteria,1H02N@1129|Synechococcus	1117|Cyanobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R03383	RC00004,RC00014,RC00137	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
REGS1_k127_8145143_5	1218108.KB908296_gene3127	2.143e-26	117.0	COG0110@1|root,COG0110@2|Bacteria,4NNTF@976|Bacteroidetes,1I232@117743|Flavobacteriia	976|Bacteroidetes	S	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family	-	-	-	ko:K19429	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,NAD_binding_9
REGS1_k127_8145143_1	867845.KI911784_gene3077	8.383e-67	236.0	COG5522@1|root,COG5522@2|Bacteria	2|Bacteria	S	Integral membrane protein (intg_mem_TP0381)	ywaF	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
REGS1_k127_8145143_2	1007104.SUS17_1188	1.072e-64	234.0	COG1612@1|root,COG1612@2|Bacteria,1MVJ4@1224|Proteobacteria,2TR0M@28211|Alphaproteobacteria,2K0QN@204457|Sphingomonadales	204457|Sphingomonadales	O	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
REGS1_k127_8145143_0	926569.ANT_29100	2.002e-68	239.0	COG1656@1|root,COG1656@2|Bacteria,2G6GZ@200795|Chloroflexi	200795|Chloroflexi	H	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
REGS1_k127_8145143_6	1122925.KB895387_gene2807	0.0001307	48.0	2DREZ@1|root,33BFB@2|Bacteria,1UPXP@1239|Firmicutes,4IVCS@91061|Bacilli,2743X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8145143_4	926569.ANT_06130	1.285e-27	112.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011,LysM,YkuD
REGS1_k127_8157416_3	1173029.JH980292_gene614	2.021e-17	90.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
REGS1_k127_8157416_2	926560.KE387023_gene1157	1.745e-47	177.0	COG2128@1|root,COG2128@2|Bacteria,1WMFR@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
REGS1_k127_8157416_0	324602.Caur_2513	4.289e-201	631.0	COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi,3766I@32061|Chloroflexia	32061|Chloroflexia	Q	PFAM homogentisate 12-dioxygenase	-	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
REGS1_k127_8157416_4	1463887.KL589976_gene5943	0.0008033	50.0	COG1572@1|root,COG1572@2|Bacteria,2H1Z9@201174|Actinobacteria	201174|Actinobacteria	S	CARDB	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CARDB,F5_F8_type_C
REGS1_k127_8157416_1	926569.ANT_15490	1.776e-71	244.0	COG1217@1|root,COG1217@2|Bacteria,2G5NQ@200795|Chloroflexi	200795|Chloroflexi	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_8160065_1	326427.Cagg_2104	1.2e-20	96.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	ntcA	-	-	ko:K01420,ko:K10716,ko:K10914,ko:K16922	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko01002,ko02000,ko03000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_8160065_0	926550.CLDAP_17040	2.19e-93	332.0	COG5276@1|root,COG5276@2|Bacteria,2G8F2@200795|Chloroflexi	200795|Chloroflexi	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
REGS1_k127_8184178_3	926569.ANT_17130	1.243e-26	109.0	COG4213@1|root,COG4213@2|Bacteria,2G6C4@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K10543,ko:K10546	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	Peripla_BP_4
REGS1_k127_8184178_0	1499967.BAYZ01000170_gene5499	2.032e-201	639.0	COG1129@1|root,COG1129@2|Bacteria,2NPR8@2323|unclassified Bacteria	2|Bacteria	G	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	xylG	GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015148,GO:0015749,GO:0015750,GO:0015753,GO:0017076,GO:0019321,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042732,GO:0043167,GO:0043168,GO:0044238,GO:0044281,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363	3.6.3.17	ko:K02056,ko:K10545,ko:K10548	ko02010,map02010	M00215,M00216,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.4,3.A.1.2.5	-	iECABU_c1320.ECABU_c40100,iECP_1309.ECP_3670,iSF_1195.SF3611,iS_1188.S4158	ABC_tran
REGS1_k127_8184178_1	926569.ANT_17110	2.24e-159	513.0	COG4214@1|root,COG4214@2|Bacteria,2G8H9@200795|Chloroflexi	200795|Chloroflexi	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10544,ko:K10547	ko02010,map02010	M00215,M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4,3.A.1.2.5	-	-	BPD_transp_2
REGS1_k127_8184178_2	926569.ANT_28600	2.961e-97	323.0	COG1653@1|root,COG1653@2|Bacteria,2G72Y@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1
REGS1_k127_8186363_0	313628.LNTAR_12791	1.065e-98	336.0	COG3464@1|root,COG3464@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
REGS1_k127_8186363_1	1396418.BATQ01000024_gene5201	1.147e-05	49.0	COG4974@1|root,COG4974@2|Bacteria,46Z4R@74201|Verrucomicrobia,2IV5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	IS66 C-terminal element	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
REGS1_k127_8188195_0	391626.OAN307_c20090	9.324e-103	347.0	COG1653@1|root,COG1653@2|Bacteria,1N1NW@1224|Proteobacteria,2U094@28211|Alphaproteobacteria	2|Bacteria	G	ABC transporter	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	HTH_IclR,SBP_bac_1,SBP_bac_8
REGS1_k127_8188195_3	391626.OAN307_c20100	8.411e-77	267.0	COG1175@1|root,COG1175@2|Bacteria,1MVKC@1224|Proteobacteria,2U3RQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	COG1175 ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
REGS1_k127_8188195_1	391626.OAN307_c20110	7.953e-85	290.0	COG0395@1|root,COG0395@2|Bacteria,1MVVT@1224|Proteobacteria,2TU85@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K10229	ko02010,map02010	M00200,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.5	-	-	BPD_transp_1
REGS1_k127_8188195_2	1150474.JQJI01000027_gene987	4.618e-79	273.0	COG3842@1|root,COG3842@2|Bacteria,2GC81@200918|Thermotogae	200918|Thermotogae	P	ABC transporter	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE
REGS1_k127_8196651_10	926569.ANT_24820	2.365e-12	68.0	COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi	200795|Chloroflexi	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
REGS1_k127_8196651_4	926569.ANT_23120	4.415e-91	317.0	COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM peptidase C60, sortase A and B	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
REGS1_k127_8196651_7	926569.ANT_07030	7.935e-38	146.0	COG0824@1|root,COG0824@2|Bacteria,2G7HH@200795|Chloroflexi	200795|Chloroflexi	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT_2
REGS1_k127_8196651_3	383372.Rcas_3959	5.622e-110	365.0	COG2141@1|root,COG2141@2|Bacteria,2G5MF@200795|Chloroflexi,376CU@32061|Chloroflexia	32061|Chloroflexia	C	PFAM luciferase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
REGS1_k127_8196651_9	1163407.UU7_00150	6.393e-16	85.0	COG2020@1|root,COG2020@2|Bacteria,1N936@1224|Proteobacteria,1SCXB@1236|Gammaproteobacteria,1X823@135614|Xanthomonadales	135614|Xanthomonadales	O	Methyltransferase	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	PEMT
REGS1_k127_8196651_8	84588.SYNW1297	2.009e-35	141.0	COG1694@1|root,COG1694@2|Bacteria,1GA07@1117|Cyanobacteria,1H0RK@1129|Synechococcus	1117|Cyanobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
REGS1_k127_8196651_0	926550.CLDAP_19360	3.97e-308	964.0	COG0542@1|root,COG0542@2|Bacteria,2G5RA@200795|Chloroflexi	200795|Chloroflexi	O	ATPase AAA-2 domain protein	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,HTH_17,UVR
REGS1_k127_8196651_5	526227.Mesil_3100	1.841e-77	263.0	COG0225@1|root,COG0225@2|Bacteria,1WK2Z@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
REGS1_k127_8196651_6	1238182.C882_0141	4.844e-39	149.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,2TQW9@28211|Alphaproteobacteria,2JPGS@204441|Rhodospirillales	204441|Rhodospirillales	E	COG2873 O-acetylhomoserine sulfhydrylase	-	-	2.5.1.47,2.5.1.49	ko:K01738,ko:K01740	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R01287,R03601,R04859	RC00020,RC02814,RC02821,RC02848	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_2,Cys_Met_Meta_PP
REGS1_k127_8196651_2	926560.KE387023_gene2289	3.978e-124	413.0	COG3852@1|root,COG3852@2|Bacteria,1WMD2@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
REGS1_k127_8196651_1	926560.KE387023_gene1698	5.519e-179	574.0	COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1WM1W@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KOT	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Response_reg
REGS1_k127_8206034_0	330214.NIDE3777	9.266e-68	235.0	COG1488@1|root,COG1488@2|Bacteria	2|Bacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	iYO844.BSU31750	NAPRTase
REGS1_k127_8206034_1	1121033.AUCF01000003_gene3095	2.989e-33	146.0	COG1357@1|root,COG1357@2|Bacteria,1N7U9@1224|Proteobacteria,2U1FV@28211|Alphaproteobacteria,2JRHS@204441|Rhodospirillales	204441|Rhodospirillales	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
REGS1_k127_8212626_5	1499967.BAYZ01000117_gene3320	1.655e-58	205.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
REGS1_k127_8212626_1	1499967.BAYZ01000117_gene3321	7.352e-177	563.0	COG0079@1|root,COG0079@2|Bacteria,2NNZK@2323|unclassified Bacteria	2|Bacteria	E	Aminotransferase class I and II	hisD	-	1.1.1.23,2.6.1.9	ko:K00013,ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R01158,R01163,R03012,R03243	RC00006,RC00099,RC00242,RC00463,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,Histidinol_dh
REGS1_k127_8212626_2	1499967.BAYZ01000117_gene3322	1.835e-140	456.0	COG0191@1|root,COG0191@2|Bacteria,2NPSG@2323|unclassified Bacteria	2|Bacteria	G	Fructose-bisphosphate aldolase class-II	fba2	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,PHP
REGS1_k127_8212626_4	580331.Thit_1582	3.623e-86	299.0	COG0176@1|root,COG0176@2|Bacteria,1U9RA@1239|Firmicutes,24DCI@186801|Clostridia,42IE1@68295|Thermoanaerobacterales	186801|Clostridia	H	PFAM Transaldolase	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
REGS1_k127_8212626_6	1283299.AUKG01000002_gene4309	4.607e-55	205.0	COG0510@1|root,COG0510@2|Bacteria,2IAJ7@201174|Actinobacteria,4CR72@84995|Rubrobacteria	84995|Rubrobacteria	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase
REGS1_k127_8212626_3	1382306.JNIM01000001_gene2073	3.452e-89	306.0	COG2129@1|root,COG2129@2|Bacteria,2G7X0@200795|Chloroflexi	200795|Chloroflexi	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8212626_7	360911.EAT1b_2257	8.34e-45	171.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli	91061|Bacilli	K	transcriptional	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_8212626_0	1380390.JIAT01000010_gene3535	1.148e-263	833.0	COG0404@1|root,COG0665@1|root,COG0404@2|Bacteria,COG0665@2|Bacteria,2GNCW@201174|Actinobacteria,4CPSG@84995|Rubrobacteria	84995|Rubrobacteria	E	FAD dependent oxidoreductase central domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAO_M,GCV_T,GCV_T_C
REGS1_k127_8234831_1	926569.ANT_13370	1.083e-199	629.0	COG0464@1|root,COG0464@2|Bacteria,2G642@200795|Chloroflexi	200795|Chloroflexi	O	SMART AAA ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA
REGS1_k127_8234831_2	926569.ANT_13130	3.576e-103	340.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_8234831_0	926550.CLDAP_15280	5.772e-219	698.0	COG0793@1|root,COG3468@1|root,COG0793@2|Bacteria,COG3468@2|Bacteria,2G7PQ@200795|Chloroflexi	200795|Chloroflexi	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S41
REGS1_k127_8243508_3	1173029.JH980292_gene614	9.379e-09	66.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
REGS1_k127_8243508_2	1173029.JH980292_gene614	3.292e-20	101.0	COG3187@1|root,COG3187@2|Bacteria	2|Bacteria	O	response to heat	-	-	-	ko:K03668,ko:K09914	-	-	-	-	ko00000	-	-	-	META,YscW
REGS1_k127_8243508_0	485913.Krac_3644	1.435e-89	305.0	COG0179@1|root,COG0179@2|Bacteria,2G7MW@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM fumarylacetoacetate (FAA) hydrolase	-	-	3.7.1.2	ko:K16171	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000	-	-	-	FAA_hydrolase
REGS1_k127_8243508_1	1121382.JQKG01000026_gene2918	1.558e-71	243.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
REGS1_k127_8244153_1	485913.Krac_2372	1.493e-40	158.0	2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8244153_0	926569.ANT_25540	1.425e-205	654.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,2G5K6@200795|Chloroflexi	200795|Chloroflexi	L	PHP domain protein	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8,PHP
REGS1_k127_8244153_2	189426.PODO_02295	3.199e-32	131.0	2CH44@1|root,32S57@2|Bacteria,1VCKH@1239|Firmicutes,4HKXX@91061|Bacilli,26XPU@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8280825_0	926569.ANT_20750	1.679e-82	283.0	COG1307@1|root,COG1307@2|Bacteria	2|Bacteria	S	lipid binding	purD	-	-	-	-	-	-	-	-	-	-	-	DegV
REGS1_k127_8280825_1	926569.ANT_20740	4.113e-68	236.0	COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi	200795|Chloroflexi	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_8306530_1	1306174.JODP01000002_gene5612	6.84e-105	349.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria	201174|Actinobacteria	S	unusual protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
REGS1_k127_8306530_0	926569.ANT_19070	2.061e-225	710.0	COG0595@1|root,COG0595@2|Bacteria,2G611@200795|Chloroflexi	200795|Chloroflexi	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
REGS1_k127_8306530_2	926569.ANT_19060	2.464e-68	239.0	COG2518@1|root,COG2518@2|Bacteria,2G6NG@200795|Chloroflexi	200795|Chloroflexi	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_8306541_3	926569.ANT_09930	6.268e-37	149.0	COG1300@1|root,COG1668@1|root,COG1300@2|Bacteria,COG1668@2|Bacteria,2G8CN@200795|Chloroflexi	200795|Chloroflexi	CP	Stage II sporulation protein M	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC2_membrane_2,SpoIIM
REGS1_k127_8306541_2	518766.Rmar_1910	2.588e-46	176.0	COG1234@1|root,COG1234@2|Bacteria,4PM5W@976|Bacteroidetes,1FJ9T@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
REGS1_k127_8306541_1	926569.ANT_09940	2.049e-74	255.0	COG1403@1|root,COG1403@2|Bacteria,2G6RY@200795|Chloroflexi	200795|Chloroflexi	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
REGS1_k127_8306541_0	926550.CLDAP_29040	8.822e-76	264.0	COG1090@1|root,COG1090@2|Bacteria,2G69K@200795|Chloroflexi	200795|Chloroflexi	S	NAD-dependent epimerase dehydratase	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
REGS1_k127_8344412_0	1479238.JQMZ01000001_gene1911	3.914e-272	851.0	COG0673@1|root,COG1063@1|root,COG0673@2|Bacteria,COG1063@2|Bacteria,1MZIG@1224|Proteobacteria,2UB61@28211|Alphaproteobacteria,43YUF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_8344458_5	2340.JV46_02050	2.995e-31	132.0	COG0664@1|root,COG3202@1|root,COG0664@2|Bacteria,COG3202@2|Bacteria,1N61M@1224|Proteobacteria	1224|Proteobacteria	CT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TLC,cNMP_binding
REGS1_k127_8344458_0	926549.KI421517_gene3934	6.999e-312	974.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE4A@976|Bacteroidetes,47KBI@768503|Cytophagia	976|Bacteroidetes	C	Dehydrogenase E1 component	pdhB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
REGS1_k127_8344458_3	1128421.JAGA01000002_gene1768	3.926e-109	366.0	COG0508@1|root,COG0508@2|Bacteria,2NNZ8@2323|unclassified Bacteria	2|Bacteria	C	e3 binding domain	bfmBB	-	2.3.1.168,2.3.1.61	ko:K00658,ko:K09699	ko00020,ko00280,ko00310,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00280,map00310,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00036	R02570,R02571,R02662,R03174,R04097,R08549,R10998	RC00004,RC02727,RC02833,RC02870	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
REGS1_k127_8344458_6	1121946.AUAX01000016_gene4690	1.305e-27	117.0	COG2020@1|root,COG2020@2|Bacteria,2IP2M@201174|Actinobacteria,4DGDW@85008|Micromonosporales	201174|Actinobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_8344458_1	926569.ANT_00050	1.34e-217	683.0	COG1249@1|root,COG1249@2|Bacteria,2G5MR@200795|Chloroflexi	200795|Chloroflexi	C	Pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpd	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_8344458_2	926569.ANT_26630	2.821e-133	431.0	COG0667@1|root,COG0667@2|Bacteria,2G5VT@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_8344458_7	864565.HMPREF0379_1392	0.0009685	48.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,25RWM@186804|Peptostreptococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8344458_4	926569.ANT_05100	7.183e-50	181.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
REGS1_k127_8363396_10	867845.KI911784_gene654	4.939e-23	101.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
REGS1_k127_8363396_9	1379698.RBG1_1C00001G0504	2.989e-29	121.0	COG0629@1|root,COG0629@2|Bacteria,2NPP5@2323|unclassified Bacteria	2|Bacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
REGS1_k127_8363396_8	526222.Desal_2901	3.812e-40	156.0	COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_8363396_12	768710.DesyoDRAFT_1514	2.62e-15	78.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
REGS1_k127_8363396_14	1382359.JIAL01000001_gene1287	7.509e-09	60.0	COG0607@1|root,32YCZ@2|Bacteria,3Y5Z1@57723|Acidobacteria	57723|Acidobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
REGS1_k127_8363396_2	926569.ANT_24700	9.279e-153	492.0	COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi	200795|Chloroflexi	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
REGS1_k127_8363396_1	926569.ANT_28990	3.871e-174	555.0	COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
REGS1_k127_8363396_0	926569.ANT_31250	0.0	1090.0	COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi	200795|Chloroflexi	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_8363396_6	926569.ANT_01000	2.909e-53	196.0	COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi	200795|Chloroflexi	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
REGS1_k127_8363396_3	926569.ANT_00990	2.546e-86	295.0	COG1215@1|root,COG1215@2|Bacteria,2GA7S@200795|Chloroflexi	200795|Chloroflexi	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_8363396_15	386456.JQKN01000004_gene177	0.0002546	52.0	arCOG06670@1|root,arCOG06670@2157|Archaea,2Y58G@28890|Euryarchaeota	28890|Euryarchaeota	L	Nuclease-related domain	-	-	-	-	-	-	-	-	-	-	-	-	NERD
REGS1_k127_8363396_4	1218108.KB908292_gene1461	7.061e-62	230.0	28NBJ@1|root,2ZBEV@2|Bacteria,4NGUD@976|Bacteroidetes,1HXQ8@117743|Flavobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8363396_7	926569.ANT_28940	5.169e-50	189.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
REGS1_k127_8363396_11	1408254.T458_12965	3.154e-22	98.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli,26ZAP@186822|Paenibacillaceae	91061|Bacilli	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
REGS1_k127_8363396_5	479433.Caci_1318	4.024e-54	194.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
REGS1_k127_8365203_24	1128427.KB904821_gene807	7.92e-05	51.0	COG0617@1|root,COG0617@2|Bacteria,1G1NC@1117|Cyanobacteria,1H8N7@1150|Oscillatoriales	1117|Cyanobacteria	J	PFAM Poly A polymerase head domain	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
REGS1_k127_8365203_10	926569.ANT_14170	9.381e-73	250.0	COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi	200795|Chloroflexi	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
REGS1_k127_8365203_9	926569.ANT_14160	2.031e-86	289.0	COG1435@1|root,COG1435@2|Bacteria,2G6DP@200795|Chloroflexi	200795|Chloroflexi	F	PFAM thymidine kinase	tdk	GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.1.21	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01567,R02099,R08233	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TK
REGS1_k127_8365203_13	926569.ANT_25140	1.128e-56	205.0	COG0202@1|root,COG0254@1|root,COG0202@2|Bacteria,COG0254@2|Bacteria,2G75A@200795|Chloroflexi	200795|Chloroflexi	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
REGS1_k127_8365203_17	926569.ANT_25130	2.596e-34	133.0	COG0211@1|root,COG0211@2|Bacteria,2G7BE@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
REGS1_k127_8365203_19	926569.ANT_25120	1.623e-28	121.0	COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi	200795|Chloroflexi	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
REGS1_k127_8365203_21	1123373.ATXI01000006_gene185	9.442e-22	107.0	COG0616@1|root,COG0616@2|Bacteria,2GH6V@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
REGS1_k127_8365203_22	926690.KE386573_gene271	4.648e-21	107.0	arCOG01312@1|root,arCOG01312@2157|Archaea,2XVGY@28890|Euryarchaeota,23VD8@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
REGS1_k127_8365203_16	1382356.JQMP01000003_gene2027	2.5e-45	172.0	COG0412@1|root,COG0412@2|Bacteria,2G9WC@200795|Chloroflexi,27Z94@189775|Thermomicrobia	189775|Thermomicrobia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
REGS1_k127_8365203_1	926569.ANT_19800	2.404e-199	644.0	COG0210@1|root,COG0210@2|Bacteria,2G7VU@200795|Chloroflexi	200795|Chloroflexi	F	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8365203_14	103690.17133484	9.261e-56	212.0	COG5542@1|root,COG5542@2|Bacteria,1GDW7@1117|Cyanobacteria,1HIN0@1161|Nostocales	1117|Cyanobacteria	S	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8365203_0	926569.ANT_19790	5.241e-208	670.0	COG0210@1|root,COG0210@2|Bacteria,2G86J@200795|Chloroflexi	200795|Chloroflexi	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_8365203_6	1242864.D187_000739	7.806e-111	366.0	COG1940@1|root,COG1940@2|Bacteria,1R7YN@1224|Proteobacteria,42QSZ@68525|delta/epsilon subdivisions,2WN50@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
REGS1_k127_8365203_15	926569.ANT_19780	1.763e-54	204.0	COG2887@1|root,COG2887@2|Bacteria,2G8SQ@200795|Chloroflexi	200795|Chloroflexi	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
REGS1_k127_8365203_12	1192034.CAP_8495	1.005e-62	227.0	COG4632@1|root,COG4632@2|Bacteria,1PIAX@1224|Proteobacteria,43DRZ@68525|delta/epsilon subdivisions,2WYR4@28221|Deltaproteobacteria,2Z0EH@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
REGS1_k127_8365203_7	926569.ANT_14370	3.349e-107	355.0	COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi	200795|Chloroflexi	S	Protein of unknown function (DUF1385)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF1385
REGS1_k127_8365203_4	926569.ANT_14380	5.406e-169	543.0	COG0624@1|root,COG0624@2|Bacteria,2G5KY@200795|Chloroflexi	200795|Chloroflexi	E	peptidase dimerisation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_8365203_2	926569.ANT_11300	4.972e-193	617.0	COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi	200795|Chloroflexi	E	PFAM extracellular solute-binding protein, family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_8365203_23	926569.ANT_11310	1.098e-20	93.0	COG1314@1|root,COG1314@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secG	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
REGS1_k127_8365203_5	926569.ANT_11320	1.424e-118	391.0	COG0613@1|root,COG0613@2|Bacteria,2G9BU@200795|Chloroflexi	200795|Chloroflexi	S	SMART phosphoesterase PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8365203_20	926569.ANT_22410	8.051e-26	109.0	COG0360@1|root,COG0360@2|Bacteria,2G7DG@200795|Chloroflexi	200795|Chloroflexi	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
REGS1_k127_8365203_11	926569.ANT_22420	5.174e-64	221.0	COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi	200795|Chloroflexi	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
REGS1_k127_8365203_18	926569.ANT_22430	1.788e-29	119.0	COG0238@1|root,COG0238@2|Bacteria,2G756@200795|Chloroflexi	200795|Chloroflexi	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
REGS1_k127_8365203_8	926569.ANT_22440	7.224e-94	324.0	COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi	200795|Chloroflexi	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase,Rotamase_3,SurA_N_3
REGS1_k127_8365203_3	926569.ANT_22450	2.008e-182	600.0	COG1196@1|root,COG1196@2|Bacteria,2G64A@200795|Chloroflexi	200795|Chloroflexi	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
REGS1_k127_839289_10	887929.HMP0721_2517	5.02e-09	59.0	2DGK2@1|root,2ZWBC@2|Bacteria,1W4NY@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_839289_5	926569.ANT_01360	1.846e-85	286.0	COG0353@1|root,COG0353@2|Bacteria,2G6CT@200795|Chloroflexi	200795|Chloroflexi	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
REGS1_k127_839289_7	926569.ANT_01350	4.418e-34	133.0	COG0718@1|root,COG0718@2|Bacteria	2|Bacteria	S	YbaB/EbfC DNA-binding family	ybaB	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363	-	ko:K06187,ko:K09747	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	YbaB_DNA_bd
REGS1_k127_839289_1	926569.ANT_01340	4.292e-155	507.0	COG2812@1|root,COG2812@2|Bacteria,2G5PK@200795|Chloroflexi	200795|Chloroflexi	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
REGS1_k127_839289_9	1455608.JDTH01000001_gene3165	5.03e-11	70.0	COG1525@1|root,COG4945@1|root,arCOG08231@1|root,arCOG01310@2157|Archaea,arCOG03192@2157|Archaea,arCOG08231@2157|Archaea,2XTAN@28890|Euryarchaeota,23T0I@183963|Halobacteria	183963|Halobacteria	L	COG1525 Micrococcal nuclease (thermonuclease) homologs	-	-	-	-	-	-	-	-	-	-	-	-	LTD,SNase
REGS1_k127_839289_2	926569.ANT_25030	4.414e-101	339.0	COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
REGS1_k127_839289_0	338969.Rfer_0358	5.045e-175	558.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,4ADNV@80864|Comamonadaceae	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_839289_6	338969.Rfer_0357	1.124e-75	256.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,4ABCM@80864|Comamonadaceae	28216|Betaproteobacteria	P	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
REGS1_k127_839289_3	243233.MCA1900	9.535e-93	314.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,1RMR8@1236|Gammaproteobacteria,1XF2R@135618|Methylococcales	135618|Methylococcales	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
REGS1_k127_839289_8	1122917.KB899659_gene4942	5.676e-22	98.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli,2751D@186822|Paenibacillaceae	91061|Bacilli	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
REGS1_k127_839289_4	653733.Selin_1325	3.042e-87	312.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	cyaK	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_8423242_17	926569.ANT_31060	1.74e-31	131.0	COG1011@1|root,COG1011@2|Bacteria,2G787@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.10	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_8423242_11	383372.Rcas_4421	6.189e-60	224.0	COG0477@1|root,COG0477@2|Bacteria,2GBJF@200795|Chloroflexi,3770H@32061|Chloroflexia	32061|Chloroflexia	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_8423242_18	926569.ANT_29030	2.597e-26	111.0	2EAGR@1|root,334K0@2|Bacteria,2G730@200795|Chloroflexi	200795|Chloroflexi	S	PFAM zinc finger, SWIM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
REGS1_k127_8423242_8	525904.Tter_0098	3.254e-97	333.0	COG0477@1|root,COG2814@2|Bacteria,2NQP3@2323|unclassified Bacteria	2|Bacteria	EGP	Transmembrane secretion effector	entS	-	-	ko:K08225	-	-	-	-	ko00000,ko02000	2.A.1.38	-	-	MFS_1,MFS_3
REGS1_k127_8423242_9	398767.Glov_2228	1.657e-90	306.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,43VVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
REGS1_k127_8423242_5	926569.ANT_07760	3.239e-128	416.0	COG0388@1|root,COG0388@2|Bacteria,2G8XD@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
REGS1_k127_8423242_12	1283283.ATXA01000016_gene44	3.671e-41	156.0	COG3832@1|root,COG3832@2|Bacteria,2IKRU@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
REGS1_k127_8423242_13	456442.Mboo_0783	1.049e-36	141.0	arCOG09489@1|root,arCOG09489@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8423242_10	926569.ANT_02860	1.974e-90	310.0	COG0349@1|root,COG0349@2|Bacteria,2G74K@200795|Chloroflexi	200795|Chloroflexi	L	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
REGS1_k127_8423242_16	926569.ANT_29020	1.764e-33	135.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
REGS1_k127_8423242_3	926569.ANT_29010	1.184e-130	422.0	COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi	200795|Chloroflexi	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_8423242_14	926569.ANT_29000	1.8e-35	143.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
REGS1_k127_8423242_6	1235279.C772_00256	1.28e-126	418.0	COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4HAFY@91061|Bacilli,26DAP@186818|Planococcaceae	91061|Bacilli	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
REGS1_k127_8423242_1	926569.ANT_02400	5.74e-149	480.0	COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi	200795|Chloroflexi	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
REGS1_k127_8423242_15	926569.ANT_09420	5.849e-35	142.0	COG0543@1|root,COG0543@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	-	-	1.16.1.3,1.5.1.41	ko:K02823,ko:K05368	ko00240,ko00740,ko00860,ko01100,map00240,map00740,map00860,map01100	-	R00097,R05705	RC00126,RC00220	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
REGS1_k127_8423242_4	926569.ANT_09430	8.664e-129	419.0	COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi	200795|Chloroflexi	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
REGS1_k127_8423242_2	1173025.GEI7407_3289	3.841e-139	455.0	COG1253@1|root,COG1253@2|Bacteria,1G16U@1117|Cyanobacteria,1H75A@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM CBS domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
REGS1_k127_8423242_0	926550.CLDAP_27540	2.292e-173	561.0	COG0405@1|root,COG0405@2|Bacteria,2G5R2@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Gamma-glutamyltranspeptidase	-	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
REGS1_k127_8423242_7	926569.ANT_17240	2.227e-110	369.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,LysM,PG_binding_1,SH3_3
REGS1_k127_8437351_2	1250232.JQNJ01000001_gene3132	0.0005888	46.0	COG3677@1|root,COG3677@2|Bacteria,4NJC5@976|Bacteroidetes,1I0Y5@117743|Flavobacteriia	976|Bacteroidetes	L	ISXO2-like transposase domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
REGS1_k127_8437351_0	269482.Bcep1808_4285	3.205e-121	403.0	COG3328@1|root,COG3328@2|Bacteria,1R81T@1224|Proteobacteria,2W75T@28216|Betaproteobacteria,1KDWC@119060|Burkholderiaceae	28216|Betaproteobacteria	L	PFAM transposase, mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
REGS1_k127_8437351_1	452637.Oter_3511	5.627e-20	91.0	COG0673@1|root,COG0673@2|Bacteria,46U95@74201|Verrucomicrobia,3K969@414999|Opitutae	74201|Verrucomicrobia	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_8465388_0	926569.ANT_00530	7.888e-157	507.0	COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi	200795|Chloroflexi	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
REGS1_k127_8465388_1	1291050.JAGE01000001_gene886	1.156e-49	183.0	2BW4G@1|root,2ZAQH@2|Bacteria,1UZFJ@1239|Firmicutes,24DAB@186801|Clostridia,3WN0Q@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8465388_2	324602.Caur_2581	4.504e-30	123.0	COG4454@1|root,COG4454@2|Bacteria,2G9EX@200795|Chloroflexi	200795|Chloroflexi	P	Blue (Type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8465388_3	1382306.JNIM01000001_gene144	6.441e-21	97.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi	200795|Chloroflexi	L	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
REGS1_k127_8481257_4	1340434.AXVA01000031_gene2840	9.584e-08	54.0	2DIA4@1|root,302HW@2|Bacteria,1U5Y3@1239|Firmicutes,4IM9X@91061|Bacilli,1ZJJZ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8481257_3	926569.ANT_28270	3.398e-21	94.0	2DFYG@1|root,2ZTRA@2|Bacteria,2G9KK@200795|Chloroflexi	200795|Chloroflexi	J	Ribosomal protein S21	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
REGS1_k127_8481257_2	926569.ANT_28280	1.486e-34	133.0	COG0361@1|root,COG0361@2|Bacteria,2G7AQ@200795|Chloroflexi	200795|Chloroflexi	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
REGS1_k127_8481257_1	926569.ANT_28310	8.121e-129	419.0	COG0167@1|root,COG0167@2|Bacteria,2G5T6@200795|Chloroflexi	200795|Chloroflexi	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
REGS1_k127_8481257_0	926569.ANT_28320	4.053e-164	522.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1146@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1146@2|Bacteria,2G5M1@200795|Chloroflexi	200795|Chloroflexi	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porA	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
REGS1_k127_8495754_2	1158601.I585_02578	5.166e-33	135.0	COG2020@1|root,COG2020@2|Bacteria,1V0PB@1239|Firmicutes,4IA34@91061|Bacilli,4B51I@81852|Enterococcaceae	91061|Bacilli	O	Ergosterol biosynthesis ERG4/ERG24 family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
REGS1_k127_8495754_0	926569.ANT_30440	6.645e-57	212.0	COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi	200795|Chloroflexi	L	TIGRFAM DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
REGS1_k127_8495754_1	926569.ANT_30450	7.396e-37	146.0	28NSZ@1|root,337UE@2|Bacteria,2GA9H@200795|Chloroflexi	200795|Chloroflexi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8495754_3	1382306.JNIM01000001_gene144	5.83e-30	126.0	COG2452@1|root,COG2452@2|Bacteria,2G789@200795|Chloroflexi	200795|Chloroflexi	L	PFAM regulatory protein, MerR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
REGS1_k127_8548503_13	56107.Cylst_1497	7.283e-27	113.0	COG3453@1|root,COG3453@2|Bacteria,1G6UU@1117|Cyanobacteria,1HP49@1161|Nostocales	1117|Cyanobacteria	S	phosphatase (DUF442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF442
REGS1_k127_8548503_9	1382306.JNIM01000001_gene1923	1.335e-58	207.0	COG2606@1|root,COG2606@2|Bacteria,2G6MD@200795|Chloroflexi	200795|Chloroflexi	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
REGS1_k127_8548503_10	717606.PaecuDRAFT_4438	1.743e-56	205.0	COG0500@1|root,COG2226@2|Bacteria,1VR4R@1239|Firmicutes,4HUAS@91061|Bacilli,27563@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_8548503_5	868131.MSWAN_0806	1.645e-92	313.0	COG1741@1|root,arCOG02935@2157|Archaea,2XU8Z@28890|Euryarchaeota	28890|Euryarchaeota	S	Belongs to the Pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
REGS1_k127_8548503_7	1403819.BATR01000053_gene1643	1.444e-81	278.0	COG0406@1|root,COG0406@2|Bacteria,46T4J@74201|Verrucomicrobia,2IV5M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
REGS1_k127_8548503_3	604331.AUHY01000044_gene1780	1.792e-116	387.0	COG0624@1|root,COG0624@2|Bacteria,1WIA9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Peptidase family M20 M25 M40	-	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
REGS1_k127_8548503_8	485913.Krac_5165	9.772e-63	220.0	COG2320@1|root,COG2320@2|Bacteria	2|Bacteria	Q	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	-	-	-	-	-	-	-	-	-	-	-	-	GrpB
REGS1_k127_8548503_6	316274.Haur_3900	1.408e-87	295.0	COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia	32061|Chloroflexia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_8548503_0	197221.22295068	5.255e-161	515.0	COG0399@1|root,COG0399@2|Bacteria,1G3C6@1117|Cyanobacteria	1117|Cyanobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_8548503_11	197221.22295067	2.215e-49	180.0	COG0662@1|root,COG0662@2|Bacteria,1G9ZQ@1117|Cyanobacteria	1117|Cyanobacteria	G	WxcM-like, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
REGS1_k127_8548503_12	926550.CLDAP_32470	1.003e-48	194.0	COG1807@1|root,COG1807@2|Bacteria,2G8DG@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_8548503_2	926569.ANT_06420	3.461e-122	400.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	ptmF	-	2.7.7.82	ko:K18431	ko00520,map00520	-	R10182	RC00152	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_8548503_4	926569.ANT_06510	4.227e-105	361.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	PMT_2
REGS1_k127_8548503_1	357808.RoseRS_3336	1.559e-147	473.0	COG0529@1|root,COG2046@1|root,COG0529@2|Bacteria,COG2046@2|Bacteria,2G7JD@200795|Chloroflexi,376A2@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of activated sulfate	cysC	-	2.7.7.4	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,ATP-sulfurylase,PUA_2
REGS1_k127_8549598_3	926569.ANT_18550	7.913e-15	76.0	COG1752@1|root,COG1752@2|Bacteria,2G70S@200795|Chloroflexi	200795|Chloroflexi	S	PFAM Patatin	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
REGS1_k127_8549598_0	326427.Cagg_2502	2.071e-141	459.0	COG0520@1|root,COG0520@2|Bacteria,2G62I@200795|Chloroflexi,3770T@32061|Chloroflexia	32061|Chloroflexia	E	PFAM aminotransferase class V	-	-	5.1.1.17	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	M00673	R04147	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5
REGS1_k127_8549598_2	926569.ANT_18530	1.17e-60	212.0	COG0691@1|root,COG0691@2|Bacteria,2G6NE@200795|Chloroflexi	200795|Chloroflexi	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
REGS1_k127_8549598_1	243233.MCA2067	1.797e-70	240.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1XDJM@135618|Methylococcales	1236|Gammaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
REGS1_k127_8564786_3	1232410.KI421421_gene3466	4.451e-50	180.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2WQ2M@28221|Deltaproteobacteria,43V3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
REGS1_k127_8564786_8	1449353.JQMQ01000005_gene145	2.056e-08	62.0	COG2161@1|root,COG2161@2|Bacteria,2IQ72@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_8564786_6	322710.Avin_50230	2.862e-27	117.0	COG1669@1|root,COG1669@2|Bacteria,1N17I@1224|Proteobacteria,1SDT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
REGS1_k127_8564786_5	322710.Avin_50240	1.977e-39	149.0	COG2361@1|root,COG2361@2|Bacteria,1N6ZA@1224|Proteobacteria,1SBHC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
REGS1_k127_8564786_0	1174528.JH992888_gene253	3.768e-113	402.0	COG0553@1|root,COG0553@2|Bacteria,1G4KZ@1117|Cyanobacteria,1JM8Z@1189|Stigonemataceae	1117|Cyanobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
REGS1_k127_8564786_1	926550.CLDAP_21160	5.65e-112	372.0	COG2810@1|root,COG2810@2|Bacteria,2G83C@200795|Chloroflexi	200795|Chloroflexi	V	amidase activity	-	-	-	ko:K07504	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_8564786_7	1244869.H261_08843	7.394e-24	106.0	2E33J@1|root,32Y3P@2|Bacteria,1N9JJ@1224|Proteobacteria,2UFJ8@28211|Alphaproteobacteria,2JUF0@204441|Rhodospirillales	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8564786_4	247490.KSU1_C1415	1.446e-40	153.0	COG4190@1|root,COG4190@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
REGS1_k127_8564786_2	1232410.KI421421_gene3470	2.365e-108	355.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,43SB3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF3362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
REGS1_k127_863461_2	269797.Mbar_A2293	8.939e-28	122.0	arCOG01662@1|root,arCOG01662@2157|Archaea,2XX49@28890|Euryarchaeota,2N9SA@224756|Methanomicrobia	224756|Methanomicrobia	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
REGS1_k127_863461_3	269482.Bcep1808_0979	3.952e-06	58.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,2VNMX@28216|Betaproteobacteria,1K072@119060|Burkholderiaceae	28216|Betaproteobacteria	I	PFAM alpha beta hydrolase fold	pldB	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
REGS1_k127_863461_1	404589.Anae109_3857	1.08e-45	177.0	COG3829@1|root,COG3829@2|Bacteria,1QVJM@1224|Proteobacteria,43CC9@68525|delta/epsilon subdivisions,2X7N5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
REGS1_k127_863461_0	1121468.AUBR01000012_gene2593	1.366e-221	699.0	COG0365@1|root,COG0365@2|Bacteria,1UMN9@1239|Firmicutes,25GME@186801|Clostridia	186801|Clostridia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.32	ko:K08295	ko00627,ko01120,map00627,map01120	-	R00982	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
REGS1_k127_8678545_1	269799.Gmet_2437	6.331e-90	302.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_8678545_0	243231.GSU2483	8.87e-293	923.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
REGS1_k127_8678545_3	671143.DAMO_0413	1.415e-67	235.0	COG2156@1|root,COG2156@2|Bacteria,2NPIZ@2323|unclassified Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iEcE24377_1341.EcE24377A_0722,ic_1306.c0781	KdpC
REGS1_k127_8678545_2	243233.MCA2216	2.019e-88	294.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,1RPPF@1236|Gammaproteobacteria,1XER6@135618|Methylococcales	135618|Methylococcales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
REGS1_k127_8763793_2	525904.Tter_2128	4.766e-48	185.0	COG1477@1|root,COG1477@2|Bacteria,2NPJE@2323|unclassified Bacteria	2|Bacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
REGS1_k127_8763793_1	485913.Krac_4874	1.879e-83	282.0	COG0745@1|root,COG0745@2|Bacteria,2G6MM@200795|Chloroflexi	200795|Chloroflexi	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_8763793_0	485913.Krac_4875	7.541e-86	303.0	COG5002@1|root,COG5002@2|Bacteria,2G68T@200795|Chloroflexi	200795|Chloroflexi	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	2CSK_N,HAMP,HATPase_c,HisKA
REGS1_k127_8763793_3	109760.SPPG_04074T0	8.971e-32	132.0	2BD1A@1|root,2S11B@2759|Eukaryota,3A3GN@33154|Opisthokonta,3P3WI@4751|Fungi	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SET
REGS1_k127_8763793_4	525904.Tter_2446	3.823e-22	100.0	COG2197@1|root,COG2197@2|Bacteria,2NRIC@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
REGS1_k127_8796039_3	1128421.JAGA01000003_gene3641	7.71e-31	126.0	COG1999@1|root,COG1999@2|Bacteria,2NRAY@2323|unclassified Bacteria	2|Bacteria	S	SCO1/SenC	hyaE	GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277	-	ko:K03619,ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	HyaE,SCO1-SenC
REGS1_k127_8796039_2	926569.ANT_05250	1.461e-43	169.0	COG3346@1|root,COG3346@2|Bacteria	2|Bacteria	S	mitochondrial respiratory chain complex IV assembly	surf1	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	ko:K14998	-	-	-	-	ko00000,ko03029	3.D.4.8	-	-	SURF1
REGS1_k127_8796039_0	926569.ANT_05240	1.901e-134	445.0	COG0109@1|root,COG1612@1|root,COG0109@2|Bacteria,COG1612@2|Bacteria,2G5UC@200795|Chloroflexi	200795|Chloroflexi	H	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	COX15-CtaA,UbiA
REGS1_k127_8796039_1	1382356.JQMP01000003_gene2108	3.317e-80	289.0	COG5617@1|root,COG5617@2|Bacteria	2|Bacteria	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,PTPS_related
REGS1_k127_8870547_0	1382359.JIAL01000001_gene184	3.628e-30	121.0	COG1228@1|root,COG1228@2|Bacteria,3Y47R@57723|Acidobacteria,2JP2Q@204432|Acidobacteriia	204432|Acidobacteriia	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
REGS1_k127_8870547_3	485916.Dtox_0163	3.13e-07	55.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_37
REGS1_k127_8870547_2	648996.Theam_0037	5.966e-08	64.0	29WNC@1|root,30I97@2|Bacteria,2G5GG@200783|Aquificae	200783|Aquificae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8870547_1	706587.Desti_3408	4.253e-14	82.0	COG2887@1|root,COG2887@2|Bacteria,1RAZ0@1224|Proteobacteria,42R3A@68525|delta/epsilon subdivisions,2WN5C@28221|Deltaproteobacteria,2MSBW@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
REGS1_k127_8944577_0	926569.ANT_16350	4.145e-298	924.0	COG0449@1|root,COG0449@2|Bacteria,2G5T5@200795|Chloroflexi	200795|Chloroflexi	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
REGS1_k127_8944577_3	626939.HMPREF9443_02043	1.244e-07	64.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4H2A2@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_8944577_1	926569.ANT_08060	1.416e-126	413.0	COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi	200795|Chloroflexi	M	PFAM sugar isomerase (SIS)	-	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	SIS
REGS1_k127_8944577_2	926569.ANT_18250	4.272e-14	80.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_24,HTH_34
REGS1_k127_8944957_1	1121378.KB899756_gene3210	3.823e-16	89.0	COG3293@1|root,2ZJP3@2|Bacteria	2|Bacteria	L	DDE superfamily endonuclease	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_4,HTH_Tnp_4
REGS1_k127_8944957_0	1172188.KB911822_gene1054	3.041e-48	173.0	COG2132@1|root,COG2132@2|Bacteria,2ICI4@201174|Actinobacteria,4FIU6@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
REGS1_k127_8965752_1	1267533.KB906738_gene2407	1.488e-71	245.0	2FCTA@1|root,344W8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8965752_0	1267533.KB906738_gene2408	4.413e-120	389.0	COG1215@1|root,COG1215@2|Bacteria,3Y9FH@57723|Acidobacteria,2JP7S@204432|Acidobacteriia	204432|Acidobacteriia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_8965752_2	1267533.KB906738_gene2409	4.052e-62	219.0	COG3222@1|root,COG3222@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2064)	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
REGS1_k127_8969177_2	1155714.KB891987_gene3346	8.517e-05	55.0	COG3469@1|root,COG3469@2|Bacteria,2GJH0@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_18,fn3
REGS1_k127_8969177_0	1313172.YM304_08050	9.119e-39	163.0	2DFIR@1|root,2ZS07@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8969177_1	267608.RSp0476	4.591e-19	101.0	COG3209@1|root,COG4105@1|root,COG3209@2|Bacteria,COG4105@2|Bacteria,1MVV1@1224|Proteobacteria,2VMJI@28216|Betaproteobacteria,1K0C1@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Rhs_assc_core RHS repeat-associated core domain protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,PAAR_motif,Peptidase_C39,RHS,RHS_repeat
REGS1_k127_8970087_2	926569.ANT_30490	1.325e-48	179.0	COG0496@1|root,COG0496@2|Bacteria	2|Bacteria	P	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
REGS1_k127_8970087_4	292563.Cyast_1064	1.8e-32	129.0	COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria	1117|Cyanobacteria	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_8970087_3	316274.Haur_3982	2.815e-36	149.0	COG1028@1|root,COG1028@2|Bacteria,2G9VV@200795|Chloroflexi,377FY@32061|Chloroflexia	32061|Chloroflexia	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_8970087_1	1288484.APCS01000012_gene954	2.471e-53	194.0	COG2191@1|root,COG2191@2|Bacteria	2|Bacteria	C	Formylmethanofuran dehydrogenase, subunit e	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
REGS1_k127_8970087_5	522772.Dacet_1796	1.741e-19	94.0	COG2146@1|root,COG2146@2|Bacteria,2GG11@200930|Deferribacteres	200930|Deferribacteres	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
REGS1_k127_8970087_0	646529.Desaci_3265	5.848e-70	252.0	COG3303@1|root,COG3303@2|Bacteria,1VTAV@1239|Firmicutes,24ZND@186801|Clostridia,264N1@186807|Peptococcaceae	186801|Clostridia	P	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8980373_2	1382356.JQMP01000001_gene796	1.544e-16	81.0	COG1225@1|root,COG1225@2|Bacteria,2G95Y@200795|Chloroflexi,27YNE@189775|Thermomicrobia	189775|Thermomicrobia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_8980373_1	926569.ANT_20800	5.871e-105	351.0	COG0215@1|root,COG4242@1|root,COG0215@2|Bacteria,COG4242@2|Bacteria,2G6C3@200795|Chloroflexi	200795|Chloroflexi	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8980373_0	926569.ANT_22870	1.92e-178	566.0	COG0213@1|root,COG0213@2|Bacteria,2G64G@200795|Chloroflexi	200795|Chloroflexi	F	PFAM glycosyl transferase family 3	pdp	-	2.4.2.2	ko:K00756	ko00240,ko01100,map00240,map01100	-	R01570,R01876,R02296,R02484	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
REGS1_k127_8995091_4	926569.ANT_10380	4.476e-172	552.0	COG1694@1|root,COG3956@2|Bacteria,2G5WH@200795|Chloroflexi	200795|Chloroflexi	S	TIGRFAM MazG family protein	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG,TP_methylase
REGS1_k127_8995091_12	926569.ANT_12610	1.251e-28	122.0	COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi	200795|Chloroflexi	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
REGS1_k127_8995091_13	926569.ANT_12600	1.098e-16	82.0	COG2608@1|root,COG2608@2|Bacteria	2|Bacteria	P	mercury ion transmembrane transporter activity	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
REGS1_k127_8995091_0	926569.ANT_12590	4.341e-313	979.0	COG2217@1|root,COG2217@2|Bacteria,2G5J7@200795|Chloroflexi	200795|Chloroflexi	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
REGS1_k127_8995091_5	926569.ANT_17980	1.798e-132	426.0	COG0396@1|root,COG0396@2|Bacteria,2G5S6@200795|Chloroflexi	200795|Chloroflexi	O	PFAM ABC transporter related	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
REGS1_k127_8995091_1	926569.ANT_17970	9.648e-264	817.0	COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufB	sufB	-	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
REGS1_k127_8995091_3	926569.ANT_17960	4.135e-179	572.0	COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi	200795|Chloroflexi	O	TIGRFAM FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
REGS1_k127_8995091_2	926569.ANT_17940	3.347e-181	577.0	COG0520@1|root,COG0520@2|Bacteria,2G5T3@200795|Chloroflexi	200795|Chloroflexi	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
REGS1_k127_8995091_8	926569.ANT_17930	4.107e-61	213.0	COG0822@1|root,COG0822@2|Bacteria,2G71H@200795|Chloroflexi	200795|Chloroflexi	C	SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
REGS1_k127_8995091_9	926569.ANT_17920	1.258e-38	147.0	COG2146@1|root,COG2146@2|Bacteria,2G7AG@200795|Chloroflexi	200795|Chloroflexi	P	PFAM Rieske 2Fe-2S domain protein	-	-	1.7.1.15	ko:K00363,ko:K05710	ko00360,ko00910,ko01120,ko01220,map00360,map00910,map01120,map01220	M00530,M00545	R00787,R06782,R06783	RC00098,RC00176	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske
REGS1_k127_8995091_10	324602.Caur_1277	3.633e-36	147.0	2E65M@1|root,330UB@2|Bacteria,2G8DC@200795|Chloroflexi	200795|Chloroflexi	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_8995091_7	926569.ANT_17910	1.11e-90	303.0	COG2120@1|root,COG2120@2|Bacteria	2|Bacteria	S	N-acetylglucosaminylinositol deacetylase activity	yaiS	-	-	-	-	-	-	-	-	-	-	-	PIG-L,Response_reg
REGS1_k127_8995091_6	926569.ANT_17900	3.288e-93	314.0	COG0500@1|root,COG2226@2|Bacteria,2G78Q@200795|Chloroflexi	200795|Chloroflexi	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
REGS1_k127_8995091_14	1122165.AUHS01000020_gene1448	4.143e-08	59.0	COG0680@1|root,COG0680@2|Bacteria,1NA38@1224|Proteobacteria,1SIG2@1236|Gammaproteobacteria,1JGH0@118969|Legionellales	118969|Legionellales	C	Hydrogenase maturation protease	vhtD	-	-	-	-	-	-	-	-	-	-	-	HycI
REGS1_k127_9043784_0	743299.Acife_1530	5.407e-302	935.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,1RRFQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Arsenical pump-driving ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
REGS1_k127_9043784_4	78398.KS43_13845	1.291e-49	180.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,1S7NG@1236|Gammaproteobacteria,1MTU7@122277|Pectobacterium	1236|Gammaproteobacteria	S	Arsenical resistance operon trans-acting repressor ArsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
REGS1_k127_9043784_3	535289.Dtpsy_2141	3.022e-70	241.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria,4ADSW@80864|Comamonadaceae	28216|Betaproteobacteria	T	low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
REGS1_k127_9043784_1	330214.NIDE3708	1.782e-173	550.0	COG0798@1|root,COG0798@2|Bacteria,3J0XN@40117|Nitrospirae	40117|Nitrospirae	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
REGS1_k127_9043784_2	1267535.KB906767_gene5005	1.433e-101	334.0	COG0500@1|root,COG2226@2|Bacteria,3Y4HC@57723|Acidobacteria	57723|Acidobacteria	Q	Hypothetical methyltransferase	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
REGS1_k127_9119488_1	234267.Acid_0826	8.895e-77	261.0	COG0803@1|root,COG0803@2|Bacteria,3Y97A@57723|Acidobacteria	57723|Acidobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
REGS1_k127_9119488_0	234267.Acid_0825	2.81e-129	425.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9119488_2	204669.Acid345_0447	0.0001777	46.0	COG1538@1|root,COG1538@2|Bacteria,3Y4VV@57723|Acidobacteria,2JJGT@204432|Acidobacteriia	204432|Acidobacteriia	MU	Outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
REGS1_k127_97916_3	330214.NIDE4065	4.408e-37	141.0	COG2856@1|root,COG2856@2|Bacteria	2|Bacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
REGS1_k127_97916_1	330214.NIDE1834	4.584e-80	270.0	COG3547@1|root,COG3547@2|Bacteria,3J17W@40117|Nitrospirae	40117|Nitrospirae	L	hmm pf02371	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_97916_2	937777.Deipe_1890	3.081e-44	168.0	COG3547@1|root,COG3547@2|Bacteria,1WJNA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_97916_0	330214.NIDE4063	5.311e-159	505.0	COG1748@1|root,COG1748@2|Bacteria	2|Bacteria	E	saccharopine dehydrogenase activity	lysDH	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	ELFV_dehydrog,Sacchrp_dh_C,Sacchrp_dh_NADP
## 3054 queries scanned
## Total time (seconds): 430.53996181488037
## Rate: 7.09 q/s