## Thu Oct 17 15:35:03 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/REGS1_bin.25.fa -m mmseqs --itype genome -o REGS1_bin.25 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/REGS1_bin.25 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
REGS1_k127_1003814_1	580332.Slit_1882	1.827e-279	863.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria,44V29@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_1003814_0	580332.Slit_1881	0.0	1134.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,44VG6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
REGS1_k127_1003814_2	580332.Slit_1594	4.27e-66	229.0	COG2202@1|root,COG2203@1|root,COG2972@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2972@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2WEET@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_9,dCache_1
REGS1_k127_1107464_8	1304883.KI912532_gene615	2.334e-16	80.0	COG1819@1|root,COG1819@2|Bacteria,1MVJM@1224|Proteobacteria,2VME8@28216|Betaproteobacteria,2KXTJ@206389|Rhodocyclales	206389|Rhodocyclales	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1107464_9	550540.Fbal_0621	1.427e-09	65.0	COG2050@1|root,COG2050@2|Bacteria,1RGVP@1224|Proteobacteria,1S5WY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl- CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA)	menI	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0061522,GO:0071704,GO:1901576,GO:1901661,GO:1901663	3.1.2.28	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07262	RC00004,RC00174	ko00000,ko00001,ko00002,ko01000	-	-	-	4HBT
REGS1_k127_1107464_7	1048834.TC41_1040	8.266e-19	88.0	COG2050@1|root,COG2050@2|Bacteria,1V7G2@1239|Firmicutes,4HIIA@91061|Bacilli	91061|Bacilli	Q	protein possibly involved in aromatic compounds catabolism	yuxO	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_1107464_1	395494.Galf_2161	4.329e-204	638.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,44VHG@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
REGS1_k127_1107464_2	580332.Slit_1047	3.463e-194	618.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,44W96@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
REGS1_k127_1107464_3	580332.Slit_1048	5.113e-144	460.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria,44VMV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
REGS1_k127_1107464_0	580332.Slit_1049	3.107e-272	845.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,44VHC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
REGS1_k127_1107464_6	580332.Slit_1050	4.708e-45	166.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,44W20@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
REGS1_k127_1107464_4	580332.Slit_1051	3.553e-138	445.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,44VID@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
REGS1_k127_1107464_5	580332.Slit_1052	6.147e-84	281.0	COG0515@1|root,COG0515@2|Bacteria,1NN82@1224|Proteobacteria,2VXXH@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1139451_5	580332.Slit_2574	1.248e-59	207.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,2VP40@28216|Betaproteobacteria,44W53@713636|Nitrosomonadales	28216|Betaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_1139451_2	580332.Slit_2573	2.277e-109	358.0	COG2834@1|root,COG2834@2|Bacteria,1RE9C@1224|Proteobacteria,2VSUX@28216|Betaproteobacteria,44W9W@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
REGS1_k127_1139451_0	580332.Slit_2571	6.374e-173	554.0	2BS95@1|root,32MAT@2|Bacteria,1RHA2@1224|Proteobacteria,2VYR6@28216|Betaproteobacteria,44WC5@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1139451_7	1244869.H261_08013	5.382e-10	69.0	COG4249@1|root,COG4249@2|Bacteria,1REY7@1224|Proteobacteria,2U87J@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Peptidase_C14,Sel1
REGS1_k127_1139451_4	1028800.RG540_PA12910	1.087e-100	338.0	COG0596@1|root,COG0596@2|Bacteria,1N252@1224|Proteobacteria,2UHB3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
REGS1_k127_1139451_3	1485544.JQKP01000001_gene1043	2.601e-107	357.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VRIK@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
REGS1_k127_1139451_1	1485544.JQKP01000001_gene1044	1.05e-115	378.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2VKFT@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
REGS1_k127_1139451_6	580332.Slit_2569	2.189e-10	62.0	COG4623@1|root,COG4623@2|Bacteria,1MWDS@1224|Proteobacteria,2VKSN@28216|Betaproteobacteria,44V11@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella	mltF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K18691	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	SBP_bac_3,SLT
REGS1_k127_1169432_5	580332.Slit_2248	2.904e-27	111.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,2VREE@28216|Betaproteobacteria,44VV0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
REGS1_k127_1169432_4	580332.Slit_2249	1.251e-30	122.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,44W1N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Iron-sulphur cluster assembly	iscX	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
REGS1_k127_1169432_3	580332.Slit_2250	6.721e-59	207.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,44VW0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM ferredoxin, 2Fe-2S type, ISC system	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
REGS1_k127_1169432_0	580332.Slit_2251	0.0	1033.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,44VHV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
REGS1_k127_1169432_1	580332.Slit_2252	6.775e-68	235.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,44VVM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
REGS1_k127_1169432_2	580332.Slit_2253	1.067e-61	213.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,44VWW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM iron-sulfur cluster assembly protein IscA	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
REGS1_k127_1169432_6	580332.Slit_2254	5.091e-12	65.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,44VSJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
REGS1_k127_1173648_4	580332.Slit_2620	9.023e-107	349.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,44V6E@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
REGS1_k127_1173648_3	580332.Slit_2621	1.634e-158	519.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,44VHE@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_1173648_1	580332.Slit_2622	1.647e-243	758.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,44VD5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
REGS1_k127_1173648_6	580332.Slit_2623	4.422e-54	194.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,2VT9E@28216|Betaproteobacteria,44W2C@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1173648_5	1485544.JQKP01000012_gene2149	1.297e-106	350.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,44UZK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
REGS1_k127_1173648_2	580332.Slit_0424	9.157e-235	730.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,44VCF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
REGS1_k127_1173648_0	395494.Galf_0272	1.454e-264	819.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,44V78@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_1173648_8	395494.Galf_0270	1.929e-35	141.0	2AG2G@1|root,3166U@2|Bacteria,1PWZ6@1224|Proteobacteria,2WCH4@28216|Betaproteobacteria,44W2R@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1173648_7	395494.Galf_0269	4.155e-42	156.0	2DB6R@1|root,2Z7I2@2|Bacteria,1R7AG@1224|Proteobacteria,2VQZS@28216|Betaproteobacteria,44VTJ@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1175500_3	580332.Slit_1746	2.379e-28	114.0	COG2965@1|root,COG2965@2|Bacteria,1PXB0@1224|Proteobacteria,2WCSV@28216|Betaproteobacteria,44WM5@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA replication, synthesis of RNA primer	-	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
REGS1_k127_1175500_2	580332.Slit_1745	6.784e-48	172.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,44VYS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
REGS1_k127_1175500_1	580332.Slit_1744	9.21e-74	250.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,44VTS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L9, N-terminal domain	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
REGS1_k127_1175500_0	580332.Slit_1743	2.491e-162	514.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,44VPB@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
REGS1_k127_1180816_3	580332.Slit_2925	8.558e-189	593.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,44VKA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
REGS1_k127_1180816_6	580332.Slit_2924	2.838e-55	197.0	2ADYZ@1|root,313R9@2|Bacteria,1Q78X@1224|Proteobacteria,2WABJ@28216|Betaproteobacteria,44WNK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
REGS1_k127_1180816_1	580332.Slit_2923	1.699e-304	934.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,44V72@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Glutamine synthetase, catalytic domain	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
REGS1_k127_1180816_2	580332.Slit_2922	8.495e-212	662.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,44V0Z@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD1	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
REGS1_k127_1180816_5	580332.Slit_2921	3.58e-71	243.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,44VYE@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_1180816_4	395494.Galf_2862	6.459e-122	396.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,44VJP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
REGS1_k127_1180816_9	580332.Slit_2919	1.704e-20	96.0	COG3313@1|root,COG3313@2|Bacteria,1Q968@1224|Proteobacteria,2WCHA@28216|Betaproteobacteria,44W3E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
REGS1_k127_1180816_7	266264.Rmet_2707	3.771e-37	147.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,1K9G0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
REGS1_k127_1180816_0	580332.Slit_2915	0.0	1222.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,44VN2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
REGS1_k127_1183743_6	1485545.JQLW01000012_gene1702	4.144e-07	53.0	COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Ubie_methyltran
REGS1_k127_1183743_4	580332.Slit_0130	8.639e-81	272.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,44WFV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
REGS1_k127_1183743_2	580332.Slit_0131	6.58e-234	727.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,44WAZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
REGS1_k127_1183743_3	580332.Slit_0132	4.742e-85	286.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,44WH8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
REGS1_k127_1183743_5	580332.Slit_2494	2.856e-42	158.0	COG2319@1|root,COG2319@2|Bacteria,1QZ0Z@1224|Proteobacteria	1224|Proteobacteria	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
REGS1_k127_1183743_0	1485544.JQKP01000002_gene1496	1.813e-281	871.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,44VKV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
REGS1_k127_1183743_1	580332.Slit_0134	6.962e-253	782.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,44VJ6@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
REGS1_k127_1186381_7	580332.Slit_2579	1.468e-98	325.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,44VR2@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
REGS1_k127_1186381_0	580332.Slit_2580	0.0	1351.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,44VA1@713636|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
REGS1_k127_1186381_6	580332.Slit_2581	6.29e-100	330.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,44VVH@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_1186381_1	580332.Slit_2582	1.132e-210	670.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,44VY8@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_1186381_11	580332.Slit_2583	3.745e-75	259.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,44VTT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
REGS1_k127_1186381_5	580332.Slit_2584	9.198e-130	417.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,2VINE@28216|Betaproteobacteria,44VB0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
REGS1_k127_1186381_10	1485544.JQKP01000002_gene1547	8.25e-83	284.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,44VS6@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
REGS1_k127_1186381_4	580332.Slit_2586	1.913e-165	522.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,44VH3@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
REGS1_k127_1186381_8	1485544.JQKP01000002_gene1549	1.348e-95	320.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,44VRK@713636|Nitrosomonadales	28216|Betaproteobacteria	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
REGS1_k127_1186381_2	580332.Slit_2588	4.333e-208	651.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,44VN1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_1186381_3	580332.Slit_2589	2.278e-187	589.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,44VIK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
REGS1_k127_1186381_9	580332.Slit_2590	1.517e-92	310.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,44VV3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Phosphoribosyltransferase	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
REGS1_k127_1186381_12	395494.Galf_0241	8.043e-51	187.0	COG0457@1|root,COG0457@2|Bacteria,1N260@1224|Proteobacteria,2VTG6@28216|Betaproteobacteria,44VWA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	ko:K12284	-	-	-	-	ko00000,ko02044	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
REGS1_k127_1203373_5	580332.Slit_0632	3.064e-10	61.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,44W2X@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_1203373_3	580332.Slit_0633	1.452e-43	162.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,44W0W@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_1203373_2	395494.Galf_0443	1.581e-115	376.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,44VAY@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
REGS1_k127_1203373_0	1485544.JQKP01000017_gene615	2.88e-192	606.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,44V4R@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_1203373_1	580332.Slit_0636	1.262e-135	434.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,44V8N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	NIF3 (NGG1p interacting factor 3)	ybgI	-	-	-	-	-	-	-	-	-	-	-	NIF3
REGS1_k127_1203373_4	580332.Slit_2494	5.047e-23	103.0	COG2319@1|root,COG2319@2|Bacteria,1QZ0Z@1224|Proteobacteria	1224|Proteobacteria	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
REGS1_k127_1204718_4	580332.Slit_1865	4.827e-106	346.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,44VI6@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM heavy metal efflux pump, CzcA family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
REGS1_k127_1204718_6	592316.Pat9b_2630	3.247e-28	121.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SCX4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
REGS1_k127_1204718_1	580332.Slit_1864	4.135e-234	743.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,44VFA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM efflux transporter, RND family, MFP subunit	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	CusF_Ec,HlyD_D23
REGS1_k127_1204718_2	580332.Slit_1863	5.942e-207	649.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,44VGB@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_1204718_5	580332.Slit_1862	8.486e-45	166.0	2BUWG@1|root,32Q8K@2|Bacteria,1PJWU@1224|Proteobacteria,2W88K@28216|Betaproteobacteria,44WJH@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2946
REGS1_k127_1204718_0	580332.Slit_1861	0.0	1319.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,44VAG@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
REGS1_k127_1204718_3	580332.Slit_1860	1.644e-138	443.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2VM6G@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
REGS1_k127_1204718_7	580332.Slit_1859	5.312e-17	83.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,44V2C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
REGS1_k127_1212616_17	580332.Slit_1067	8.244e-97	323.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,44V16@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_1212616_13	395494.Galf_2146	1.213e-121	394.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,44V2M@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
REGS1_k127_1212616_27	580332.Slit_1069	4.243e-43	160.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,44W05@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
REGS1_k127_1212616_16	580332.Slit_1071	2.216e-98	321.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,44VDZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
REGS1_k127_1212616_14	580332.Slit_1072	6.898e-111	360.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,44VSK@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
REGS1_k127_1212616_4	580332.Slit_1073	1.514e-265	818.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,44V6Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
REGS1_k127_1212616_20	580332.Slit_1074	1.945e-88	293.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,44VSP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
REGS1_k127_1212616_5	580332.Slit_1075	1.157e-264	819.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,44VM8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_1212616_0	580332.Slit_1076	0.0	1299.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,44UZF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
REGS1_k127_1212616_9	580332.Slit_1077	3.919e-181	571.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,44V52@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
REGS1_k127_1212616_18	580332.Slit_1078	1.072e-93	310.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,44V2Y@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
REGS1_k127_1212616_22	580332.Slit_1079	7.452e-86	289.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,44VQ4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
REGS1_k127_1212616_26	580332.Slit_1080	8.848e-48	172.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,44VWX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
REGS1_k127_1212616_1	580332.Slit_1081	0.0	1148.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,44V2B@713636|Nitrosomonadales	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
REGS1_k127_1212616_3	580332.Slit_1082	7.133e-275	850.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,44VBV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
REGS1_k127_1212616_6	580332.Slit_1083	2.915e-251	781.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,44VEU@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
REGS1_k127_1212616_21	1485544.JQKP01000010_gene816	1.279e-87	291.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,44VPW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
REGS1_k127_1212616_7	395494.Galf_2121	3.121e-233	724.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,44V4J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
REGS1_k127_1212616_12	395494.Galf_1588	1.055e-135	457.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,44WKU@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
REGS1_k127_1212616_24	395494.Galf_1848	4.15e-76	267.0	COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,2VSU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transport system periplasmic component	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
REGS1_k127_1212616_25	395494.Galf_2334	2.947e-66	243.0	COG2199@1|root,COG4192@1|root,COG2199@2|Bacteria,COG4192@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K03406,ko:K05875,ko:K07647	ko02020,ko02030,map02020,map02030	M00455	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	4HB_MCP_1,EAL,GGDEF,HAMP,HATPase_c,HisKA,MCPsignal,PAS_3,PAS_9,Response_reg
REGS1_k127_1212616_19	580332.Slit_2052	5.733e-91	309.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria,44V7N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
REGS1_k127_1212616_23	580332.Slit_2051	3.554e-83	279.0	COG3038@1|root,COG3038@2|Bacteria,1MZ7X@1224|Proteobacteria,2VS28@28216|Betaproteobacteria,44VU1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome	cybB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
REGS1_k127_1212616_10	580332.Slit_2050	1.149e-165	524.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,44VBA@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
REGS1_k127_1212616_15	580332.Slit_2049	3.338e-106	349.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,44VPX@713636|Nitrosomonadales	28216|Betaproteobacteria	M	MlaA lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
REGS1_k127_1212616_11	580332.Slit_1262	2.578e-165	523.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,2VHAG@28216|Betaproteobacteria,44VBP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
REGS1_k127_1212616_2	1485544.JQKP01000003_gene277	3.433e-297	916.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,2VIP7@28216|Betaproteobacteria,44V54@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumA	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
REGS1_k127_1212616_8	580332.Slit_1265	3.416e-204	638.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,44V5X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
REGS1_k127_1226262_4	580332.Slit_2279	1.344e-94	311.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,44V5T@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_1226262_1	580332.Slit_2280	8.634e-165	521.0	COG0240@1|root,COG0240@2|Bacteria,1RED0@1224|Proteobacteria,2W2AD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase	-	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
REGS1_k127_1226262_5	580332.Slit_2272	4.45e-89	297.0	COG3751@1|root,COG3751@2|Bacteria,1RD3H@1224|Proteobacteria,2VV8V@28216|Betaproteobacteria,44W5D@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SMART Prolyl 4-hydroxylase alpha subunit	-	-	-	ko:K07394	-	-	-	-	ko00000	-	-	-	2OG-FeII_Oxy_3
REGS1_k127_1226262_6	580332.Slit_2284	2.934e-87	289.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,44VUC@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_1226262_8	1485544.JQKP01000013_gene1849	4.835e-75	254.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria,44WEK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Bacterial protein of unknown function (DUF899)	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_1226262_0	580332.Slit_2286	3.555e-190	599.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,44V9M@713636|Nitrosomonadales	28216|Betaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
REGS1_k127_1226262_7	580332.Slit_2287	4.826e-82	275.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria,44WH3@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1226262_3	580332.Slit_2288	5.263e-119	386.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,44V64@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
REGS1_k127_1226262_9	580332.Slit_2289	5.704e-40	164.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,44W4F@713636|Nitrosomonadales	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
REGS1_k127_1226262_2	580332.Slit_2290	3.742e-162	513.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,44VGM@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
REGS1_k127_1300791_3	748247.AZKH_p0369	6.968e-82	275.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,2KWAS@206389|Rhodocyclales	28216|Betaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
REGS1_k127_1300791_2	666681.M301_1732	4.2e-106	351.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJK6@28216|Betaproteobacteria,2KMTR@206350|Nitrosomonadales	206350|Nitrosomonadales	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
REGS1_k127_1300791_1	748247.AZKH_p0367	1.148e-157	505.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VH5N@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
REGS1_k127_1300791_4	580332.Slit_0872	2.872e-58	211.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2VS6R@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1300791_0	768671.ThimaDRAFT_4264	2.055e-184	582.0	COG1979@1|root,COG1979@2|Bacteria,1QUBJ@1224|Proteobacteria,1RP7C@1236|Gammaproteobacteria,1WX8P@135613|Chromatiales	135613|Chromatiales	C	Iron-containing alcohol dehydrogenase	-	-	-	ko:K08325	ko00640,map00640	-	R02528	RC00739	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
REGS1_k127_1304123_4	1132855.KB913035_gene1726	1.386e-55	195.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,2VK65@28216|Betaproteobacteria,2KNHW@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
REGS1_k127_1304123_7	1131462.DCF50_p201	5.012e-10	68.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
REGS1_k127_1304123_6	1158292.JPOE01000002_gene3584	7.257e-45	170.0	2DMHQ@1|root,32RMG@2|Bacteria,1RI3A@1224|Proteobacteria,2VSJE@28216|Betaproteobacteria,1KP2R@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Arsenical resistance operon trans-acting repressor ArsD	arsD	-	-	-	-	-	-	-	-	-	-	-	ArsD
REGS1_k127_1304123_2	1485544.JQKP01000018_gene582	1.866e-97	319.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria,44VDD@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART Protein-tyrosine phosphatase, low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
REGS1_k127_1304123_5	395494.Galf_2398	8.961e-49	175.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,44W07@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
REGS1_k127_1304123_0	1266925.JHVX01000009_gene30	4.072e-265	863.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,2VJB8@28216|Betaproteobacteria,372U8@32003|Nitrosomonadales	28216|Betaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	tamB	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
REGS1_k127_1304123_1	1131553.JIBI01000001_gene1517	2.342e-156	512.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,2VHW1@28216|Betaproteobacteria,372KY@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Surface antigen	tama	-	-	ko:K07278	-	-	-	-	ko00000,ko02000	1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
REGS1_k127_1304123_3	1395571.TMS3_0122845	1.332e-58	207.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite permeases	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
REGS1_k127_1337094_6	580332.Slit_0863	3.181e-17	81.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,44UYJ@713636|Nitrosomonadales	1224|Proteobacteria	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
REGS1_k127_1337094_5	580332.Slit_0864	2.953e-43	159.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VU9E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
REGS1_k127_1337094_4	1121035.AUCH01000008_gene1046	7.222e-48	173.0	2EQH0@1|root,33I30@2|Bacteria,1NJ7T@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1337094_0	1485544.JQKP01000005_gene305	1.274e-274	848.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VGZY@28216|Betaproteobacteria,44W8D@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
REGS1_k127_1337094_1	1485544.JQKP01000005_gene304	2.095e-254	791.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,2VHRH@28216|Betaproteobacteria,44WCF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	IG-like fold at C-terminal of FixG, putative oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
REGS1_k127_1337094_3	580332.Slit_0876	3.246e-57	210.0	COG2703@1|root,COG2703@2|Bacteria,1MZJ3@1224|Proteobacteria,2VVGT@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1337094_7	580332.Slit_0348	6.52e-09	66.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,44VK7@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_1337094_2	580332.Slit_0877	1.13e-177	558.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,2VM9W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
REGS1_k127_1367702_6	395494.Galf_0230	1.015e-53	194.0	COG4970@1|root,COG4970@2|Bacteria,1N8HW@1224|Proteobacteria,2VWJK@28216|Betaproteobacteria,44W3X@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K10926	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	GspH,N_methyl
REGS1_k127_1367702_7	697282.Mettu_3216	1.501e-52	192.0	COG4967@1|root,COG4967@2|Bacteria,1RKKA@1224|Proteobacteria	1224|Proteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K10927	ko05111,map05111	-	-	-	ko00000,ko00001,ko02044	-	-	-	N_methyl
REGS1_k127_1367702_5	640081.Dsui_1285	3.513e-58	216.0	COG2165@1|root,COG2165@2|Bacteria,1RHHG@1224|Proteobacteria,2VT5N@28216|Betaproteobacteria,2KWMN@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K12285	-	-	-	-	ko00000,ko02044	-	-	-	N_methyl
REGS1_k127_1367702_8	292415.Tbd_0758	3.164e-21	98.0	COG4726@1|root,COG4726@2|Bacteria,1N9C7@1224|Proteobacteria,2VWCD@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	ko:K12286	-	-	-	-	ko00000,ko02044	-	-	-	-
REGS1_k127_1367702_0	395494.Galf_0234	3.558e-232	767.0	COG3420@1|root,COG3420@2|Bacteria,1NGRY@1224|Proteobacteria,2WHER@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Conserved repeat domain	-	-	-	ko:K12287	-	-	-	-	ko00000,ko02044	-	-	-	Laminin_G_3
REGS1_k127_1367702_1	580332.Slit_2597	8.702e-138	444.0	COG4972@1|root,COG4972@2|Bacteria,1N0HS@1224|Proteobacteria,2VQYY@28216|Betaproteobacteria,44VPT@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein	-	-	-	ko:K12279	-	-	-	-	ko00000,ko02044	-	-	-	PilM_2
REGS1_k127_1367702_4	580332.Slit_2596	9.01e-76	260.0	COG3166@1|root,COG3166@2|Bacteria,1RHH0@1224|Proteobacteria,2WB06@28216|Betaproteobacteria,44W3U@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Fimbrial assembly protein (PilN)	-	-	-	-	-	-	-	-	-	-	-	-	PilN
REGS1_k127_1367702_3	580332.Slit_2595	4.965e-86	293.0	COG3167@1|root,COG3167@2|Bacteria,1N1KE@1224|Proteobacteria,2VV3H@28216|Betaproteobacteria,44W3R@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	ko:K12280	-	-	-	-	ko00000,ko02044	-	-	-	T2SSM
REGS1_k127_1367702_9	1163617.SCD_n02672	1.313e-10	72.0	2DR7A@1|root,33AIK@2|Bacteria,1NGEC@1224|Proteobacteria,2VY5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	ko:K12281	-	-	-	-	ko00000,ko02044	-	-	-	-
REGS1_k127_1367702_2	580332.Slit_2593	1.458e-87	295.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMZA@28216|Betaproteobacteria,44VH7@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II and III secretion system protein	-	-	-	ko:K02453,ko:K12282	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N_2
REGS1_k127_136981_1	580332.Slit_1320	2.431e-107	351.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2VHXT@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
REGS1_k127_136981_5	580332.Slit_1319	6.703e-77	260.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2VRAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
REGS1_k127_136981_2	580332.Slit_1872	1.876e-98	323.0	COG3548@1|root,COG3548@2|Bacteria,1PGBQ@1224|Proteobacteria,2W8V4@28216|Betaproteobacteria,44WNB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
REGS1_k127_136981_3	580332.Slit_1317	4.013e-98	322.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2VQ0V@28216|Betaproteobacteria,44WMG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
REGS1_k127_136981_6	398527.Bphyt_3116	1.582e-10	70.0	2EFVN@1|root,339MW@2|Bacteria,1R005@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_136981_4	290398.Csal_2369	1.03e-89	306.0	COG1192@1|root,COG1192@2|Bacteria,1R6KZ@1224|Proteobacteria,1S9NU@1236|Gammaproteobacteria,1XQ2M@135619|Oceanospirillales	135619|Oceanospirillales	D	ATPase MipZ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
REGS1_k127_136981_8	580332.Slit_1315	6.046e-05	46.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,44VAI@713636|Nitrosomonadales	28216|Betaproteobacteria	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
REGS1_k127_136981_7	338966.Ppro_1115	3.934e-07	57.0	COG3668@1|root,COG3668@2|Bacteria,1N7G9@1224|Proteobacteria,42XIR@68525|delta/epsilon subdivisions,2WTHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_136981_0	580332.Slit_1315	2.054e-209	656.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,44VAI@713636|Nitrosomonadales	28216|Betaproteobacteria	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
REGS1_k127_1382813_10	1123508.JH636456_gene154	2.176e-57	205.0	COG0711@1|root,COG0711@2|Bacteria,2IZ3I@203682|Planctomycetes	203682|Planctomycetes	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
REGS1_k127_1382813_0	1163617.SCD_n00693	1.26e-262	816.0	COG0056@1|root,COG0056@2|Bacteria,1MVHM@1224|Proteobacteria,2VPGJ@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA2	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
REGS1_k127_1382813_6	857087.Metme_2527	2.049e-74	255.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1XGFF@135618|Methylococcales	135618|Methylococcales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
REGS1_k127_1382813_16	1387312.BAUS01000002_gene923	1.829e-06	59.0	2EATY@1|root,334VP@2|Bacteria,1NB0C@1224|Proteobacteria,2VYZU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1382813_3	338969.Rfer_1169	1.328e-114	376.0	COG0224@1|root,COG0224@2|Bacteria,1N4GR@1224|Proteobacteria,2VJRE@28216|Betaproteobacteria,4AD00@80864|Comamonadaceae	28216|Betaproteobacteria	C	ATP synthase	-	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
REGS1_k127_1382813_14	1122605.KB893626_gene2818	3.19e-38	151.0	COG1309@1|root,COG1309@2|Bacteria,4NPEQ@976|Bacteroidetes,1ISAU@117747|Sphingobacteriia	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
REGS1_k127_1382813_1	485918.Cpin_0157	1.063e-176	563.0	COG0304@1|root,COG0304@2|Bacteria,4NDVU@976|Bacteroidetes	976|Bacteroidetes	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_1382813_9	62928.azo0191	1.422e-62	219.0	COG2030@1|root,COG2030@2|Bacteria,1RGUP@1224|Proteobacteria,2VRWK@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM MaoC domain protein dehydratase	maoC	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
REGS1_k127_1382813_11	697284.ERIC2_c17450	1.543e-51	192.0	COG1028@1|root,COG1028@2|Bacteria,1TS27@1239|Firmicutes,4HDAK@91061|Bacilli,26TE6@186822|Paenibacillaceae	91061|Bacilli	IQ	related to short-chain alcohol	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
REGS1_k127_1382813_8	1268622.AVS7_01068	4.398e-64	226.0	COG0454@1|root,COG0454@2|Bacteria,1QXKI@1224|Proteobacteria	1224|Proteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_1382813_4	380394.Lferr_1674	7.322e-82	276.0	COG1305@1|root,COG1305@2|Bacteria,1R4TK@1224|Proteobacteria,1RYNT@1236|Gammaproteobacteria,2NC8J@225057|Acidithiobacillales	225057|Acidithiobacillales	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
REGS1_k127_1382813_12	202955.BBND01000015_gene1708	2.649e-51	184.0	COG1942@1|root,COG1942@2|Bacteria,1N2V3@1224|Proteobacteria,1SFKB@1236|Gammaproteobacteria,3NN6Y@468|Moraxellaceae	1236|Gammaproteobacteria	S	Tautomerase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
REGS1_k127_1382813_13	338969.Rfer_3871	9.368e-40	152.0	COG0789@1|root,COG0789@2|Bacteria,1N9D2@1224|Proteobacteria,2VX4F@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
REGS1_k127_1382813_5	436717.AOLE_00935	1.137e-78	271.0	COG0300@1|root,COG0300@2|Bacteria,1RG9T@1224|Proteobacteria,1S48Y@1236|Gammaproteobacteria,3NJ51@468|Moraxellaceae	1236|Gammaproteobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
REGS1_k127_1382813_2	395494.Galf_1515	2.55e-174	554.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,44VA2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_1382813_7	667632.KB890175_gene4081	3.525e-70	243.0	COG3467@1|root,COG3467@2|Bacteria,1MWQE@1224|Proteobacteria,2VJNR@28216|Betaproteobacteria,1K4J4@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
REGS1_k127_1382813_15	644281.MFS40622_0470	3.374e-16	79.0	COG1476@1|root,arCOG01864@2157|Archaea,2XZS8@28890|Euryarchaeota,23R7U@183939|Methanococci	183939|Methanococci	K	PFAM helix-turn-helix domain protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
REGS1_k127_1403073_9	580332.Slit_1011	0.0003328	44.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,44VWK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_1403073_5	580332.Slit_1017	5.095e-82	277.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,44VU8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
REGS1_k127_1403073_6	580332.Slit_1018	4.183e-79	273.0	COG0671@1|root,COG0671@2|Bacteria,1PSM7@1224|Proteobacteria,2WB4I@28216|Betaproteobacteria,44WMP@713636|Nitrosomonadales	28216|Betaproteobacteria	I	SMART phosphoesterase PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_1403073_4	395494.Galf_1998	7.481e-89	295.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,44VS5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF520)	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
REGS1_k127_1403073_7	580332.Slit_1020	7.122e-49	183.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,2VSCI@28216|Betaproteobacteria,44W28@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
REGS1_k127_1403073_2	580332.Slit_1021	4.634e-91	305.0	COG2110@1|root,COG2110@2|Bacteria,1MVYN@1224|Proteobacteria,2VH7H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Appr-1-p processing	-	-	-	-	-	-	-	-	-	-	-	-	Macro
REGS1_k127_1403073_0	580332.Slit_1022	3.016e-262	809.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,44V8H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
REGS1_k127_1403073_8	521719.ATXQ01000004_gene1718	5.977e-14	74.0	2EH60@1|root,33AXW@2|Bacteria,1NGBT@1224|Proteobacteria,1SGHD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2798)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
REGS1_k127_1403073_1	580332.Slit_1023	8.577e-194	606.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,44VFG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_1403073_3	395494.Galf_1990	3.042e-89	296.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,44VA2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_1417705_1	395494.Galf_2172	1.495e-87	293.0	COG0500@1|root,COG0500@2|Bacteria,1REJ2@1224|Proteobacteria,2VQ90@28216|Betaproteobacteria,44W5P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
REGS1_k127_1417705_0	1168067.JAGP01000001_gene837	4.912e-91	308.0	COG2199@1|root,COG3706@2|Bacteria,1QVPY@1224|Proteobacteria,1T2GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	CZB,GGDEF
REGS1_k127_1417705_2	313612.L8106_22119	4.259e-18	89.0	COG3668@1|root,COG3668@2|Bacteria,1G8WD@1117|Cyanobacteria,1HDM2@1150|Oscillatoriales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_1417705_3	272134.KB731324_gene1610	4.553e-09	60.0	2E7NY@1|root,3324J@2|Bacteria,1G9PZ@1117|Cyanobacteria,1HCY8@1150|Oscillatoriales	1117|Cyanobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
REGS1_k127_1441280_0	640081.Dsui_3325	1.397e-242	762.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,2KV11@206389|Rhodocyclales	206389|Rhodocyclales	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
REGS1_k127_1441280_2	580332.Slit_0960	8.811e-44	162.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,44VZC@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
REGS1_k127_1441280_1	580332.Slit_0959	2.361e-156	494.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,44VPG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
REGS1_k127_1455919_0	580332.Slit_2950	0.0	1118.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,44V8M@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
REGS1_k127_1462161_14	279714.FuraDRAFT_2096	1.266e-48	186.0	COG2197@1|root,COG2197@2|Bacteria,1R6Y9@1224|Proteobacteria,2VV7Q@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
REGS1_k127_1462161_13	318167.Sfri_1018	2.941e-59	236.0	COG4932@1|root,COG5492@1|root,COG4932@2|Bacteria,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,1RZEW@1236|Gammaproteobacteria,2QASD@267890|Shewanellaceae	1236|Gammaproteobacteria	N	PFAM Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566
REGS1_k127_1462161_18	1408444.JHYC01000004_gene692	9.011e-11	76.0	COG2706@1|root,COG2706@2|Bacteria,1RB38@1224|Proteobacteria,1SNAF@1236|Gammaproteobacteria,1JE2M@118969|Legionellales	118969|Legionellales	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1462161_6	1123073.KB899241_gene1791	4.085e-195	653.0	COG3055@1|root,COG3170@1|root,COG4625@1|root,COG3055@2|Bacteria,COG3170@2|Bacteria,COG4625@2|Bacteria,1R9K3@1224|Proteobacteria,1S1R4@1236|Gammaproteobacteria,1X91T@135614|Xanthomonadales	135614|Xanthomonadales	NU	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6
REGS1_k127_1462161_17	580332.Slit_2306	1.247e-24	108.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
REGS1_k127_1462161_11	903818.KI912268_gene2380	1.093e-73	258.0	COG2885@1|root,COG2885@2|Bacteria,3Y5IQ@57723|Acidobacteria	57723|Acidobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF937,OmpA
REGS1_k127_1462161_4	580332.Slit_2101	9.818e-279	863.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,2VJ29@28216|Betaproteobacteria,44VB5@713636|Nitrosomonadales	28216|Betaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	algC	GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_1462161_8	580332.Slit_2100	1.596e-171	542.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,44UZE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
REGS1_k127_1462161_16	580332.Slit_2099	3.769e-35	134.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2WAN7@28216|Betaproteobacteria,44W2Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
REGS1_k127_1462161_7	580332.Slit_2098	1.196e-191	599.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,44VFU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
REGS1_k127_1462161_5	580332.Slit_2097	3.706e-229	715.0	COG2114@1|root,COG2114@2|Bacteria,1QWNC@1224|Proteobacteria,2VHX9@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.2	ko:K01769	ko00230,map00230	-	R00434	RC00295	ko00000,ko00001,ko01000	-	-	-	Guanylate_cyc
REGS1_k127_1462161_2	580332.Slit_2096	0.0	1332.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,44V1N@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
REGS1_k127_1462161_0	580332.Slit_2095	0.0	1375.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,44VDF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
REGS1_k127_1462161_9	580332.Slit_2094	4.325e-165	521.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,44VJE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
REGS1_k127_1462161_3	580332.Slit_2093	6.007e-290	894.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,44V5K@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_1462161_12	580332.Slit_1236	8.073e-72	256.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2W303@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,dCache_1
REGS1_k127_1462161_15	1485544.JQKP01000017_gene638	7e-43	161.0	COG2703@1|root,COG2703@2|Bacteria,1N9YV@1224|Proteobacteria	1224|Proteobacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_1462161_10	1485544.JQKP01000002_gene1385	4.314e-125	407.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,44VNX@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
REGS1_k127_1462161_1	580332.Slit_2090	0.0	1364.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,44V7X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
REGS1_k127_14657_3	580332.Slit_0959	1.93e-95	313.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,44VPG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
REGS1_k127_14657_1	580332.Slit_0958	2.277e-165	525.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,44V4D@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
REGS1_k127_14657_4	580332.Slit_0955	3.542e-87	288.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,44VT0@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_14657_0	580332.Slit_0954	1.563e-205	643.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,44VAS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
REGS1_k127_14657_2	1163617.SCD_n00492	4.864e-122	400.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2VJCC@28216|Betaproteobacteria	28216|Betaproteobacteria	M	mechanosensitive ion channel	ynaI	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
REGS1_k127_14657_8	1485544.JQKP01000001_gene1003	4.131e-05	49.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2VJNA@28216|Betaproteobacteria,44W97@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifN	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
REGS1_k127_14657_5	580332.Slit_0953	6.582e-26	108.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,44VN3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
REGS1_k127_1478427_3	580332.Slit_0673	3.532e-163	515.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,44V1S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
REGS1_k127_1478427_7	395494.Galf_2330	3.251e-111	368.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,44V9I@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
REGS1_k127_1478427_1	395494.Galf_2331	9.542e-180	569.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,44V3Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_1478427_11	1485544.JQKP01000001_gene883	4.658e-83	281.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,44VQD@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
REGS1_k127_1478427_9	1485544.JQKP01000001_gene882	1.775e-100	332.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,44VBW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
REGS1_k127_1478427_0	395494.Galf_1866	3.401e-265	820.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,44VI7@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
REGS1_k127_1478427_10	748247.AZKH_1521	2.778e-98	336.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria,2KUUB@206389|Rhodocyclales	206389|Rhodocyclales	V	Biotin-lipoyl like	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_1478427_5	1562701.BBOF01000059_gene1764	5.751e-151	493.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2VJGS@28216|Betaproteobacteria,1K0CB@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Major facilitator superfamily	emrB	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
REGS1_k127_1478427_8	580332.Slit_2343	2.574e-101	337.0	COG1711@1|root,COG1711@2|Bacteria,1RIA0@1224|Proteobacteria,2VIHJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3014)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3014
REGS1_k127_1478427_21	1265502.KB905938_gene2432	3.551e-09	61.0	2DT41@1|root,33IK2@2|Bacteria,1NNPM@1224|Proteobacteria,2W6H7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1478427_14	580332.Slit_2018	6.771e-45	164.0	2DBSM@1|root,32TY0@2|Bacteria,1N5UN@1224|Proteobacteria,2VV1Y@28216|Betaproteobacteria,44WI0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
REGS1_k127_1478427_18	580332.Slit_2018	1.739e-24	106.0	2DBSM@1|root,32TY0@2|Bacteria,1N5UN@1224|Proteobacteria,2VV1Y@28216|Betaproteobacteria,44WI0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
REGS1_k127_1478427_15	176280.SE_2204	3.506e-35	156.0	COG0497@1|root,COG0497@2|Bacteria	2|Bacteria	L	DNA recombination	-	-	-	ko:K15482,ko:K20345	ko02024,ko05134,map02024,map05134	-	-	-	ko00000,ko00001,ko02000	3.A.1.112,8.A.1	-	-	AAA_11,AAA_12,HlyD_3,MotA_ExbB,Tubulin_2,zf-C4_Topoisom
REGS1_k127_1478427_4	1265503.KB905166_gene934	1.695e-162	517.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
REGS1_k127_1478427_6	268407.PWYN_22775	1.949e-142	458.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26TF8@186822|Paenibacillaceae	91061|Bacilli	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
REGS1_k127_1478427_17	1485544.JQKP01000005_gene342	1.43e-29	120.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,44VZU@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_1478427_19	1502770.JQMG01000001_gene1744	4.525e-14	77.0	2FJZ4@1|root,34BMG@2|Bacteria,1P0NJ@1224|Proteobacteria,2W405@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1478427_2	1249480.B649_01625	2.061e-178	580.0	COG2203@1|root,COG2206@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1RAQS@1224|Proteobacteria,42QQI@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HD,HD_5,PAS,PAS_4,PAS_8,PAS_9,Response_reg,sCache_2
REGS1_k127_1478427_13	314345.SPV1_05158	3.177e-45	169.0	COG2703@1|root,COG2703@2|Bacteria,1NHAX@1224|Proteobacteria	1224|Proteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
REGS1_k127_1478427_16	580332.Slit_2211	7.762e-30	129.0	COG4254@1|root,COG4254@2|Bacteria,1PGBS@1224|Proteobacteria,2VQEE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
REGS1_k127_1478427_12	580332.Slit_2212	6.621e-69	252.0	COG0457@1|root,COG0457@2|Bacteria,1P464@1224|Proteobacteria,2VMYZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF560)	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
REGS1_k127_1478427_20	641524.ADICYQ_0104	1.639e-10	72.0	COG2373@1|root,COG3291@1|root,COG3386@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,4NT8Z@976|Bacteroidetes,47UGR@768503|Cytophagia	976|Bacteroidetes	G	PFAM SMP-30 Gluconolaconase	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
REGS1_k127_1486191_22	395494.Galf_1932	8.654e-19	88.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2W14Y@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_1486191_10	395494.Galf_1931	2.516e-81	276.0	COG2128@1|root,COG2128@2|Bacteria,1RBG0@1224|Proteobacteria,2VKY2@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
REGS1_k127_1486191_4	395494.Galf_1930	2.17e-149	477.0	COG2207@1|root,COG2207@2|Bacteria,1N0FA@1224|Proteobacteria,2VKR0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
REGS1_k127_1486191_29	1515746.HR45_07860	4.487e-11	66.0	COG5660@1|root,COG5660@2|Bacteria,1NH4R@1224|Proteobacteria,1SH4J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Transmembrane anti-sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
REGS1_k127_1486191_12	381666.H16_B2413	1.712e-57	207.0	COG1595@1|root,COG1595@2|Bacteria,1RHKM@1224|Proteobacteria,2VRMP@28216|Betaproteobacteria,1K198@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_1486191_20	666685.R2APBS1_3162	9.509e-21	93.0	COG1225@1|root,COG1225@2|Bacteria,1NBR9@1224|Proteobacteria,1SDMZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_1486191_16	1123228.AUIH01000001_gene1294	7.886e-30	122.0	COG1225@1|root,COG1225@2|Bacteria,1NBR9@1224|Proteobacteria,1SDMZ@1236|Gammaproteobacteria,1XQQH@135619|Oceanospirillales	135619|Oceanospirillales	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_1486191_3	580332.Slit_1776	2.74e-236	735.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	Bac_surface_Ag
REGS1_k127_1486191_17	525897.Dbac_2257	2.129e-26	110.0	COG2161@1|root,COG2161@2|Bacteria,1N6YR@1224|Proteobacteria,42TJ9@68525|delta/epsilon subdivisions,2WRWA@28221|Deltaproteobacteria,2MCPH@213115|Desulfovibrionales	28221|Deltaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	ko:K18923	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
REGS1_k127_1486191_13	580332.Slit_1771	5.192e-48	172.0	COG2026@1|root,COG2026@2|Bacteria,1MZ76@1224|Proteobacteria,2VV06@28216|Betaproteobacteria	28216|Betaproteobacteria	DJ	TIGRFAM Addiction module toxin, RelE StbE	relE	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
REGS1_k127_1486191_1	580332.Slit_1765	0.0	1260.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,44VCB@713636|Nitrosomonadales	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
REGS1_k127_1486191_11	555778.Hneap_1674	1.952e-76	270.0	COG0582@1|root,COG0582@2|Bacteria,1MX7E@1224|Proteobacteria,1RNX5@1236|Gammaproteobacteria,1X192@135613|Chromatiales	135613|Chromatiales	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
REGS1_k127_1486191_32	1218075.BAYA01000007_gene2727	1.898e-05	52.0	2BGVX@1|root,32AVR@2|Bacteria,1PXHB@1224|Proteobacteria,2WCX6@28216|Betaproteobacteria,1KBFD@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Excisionase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Exc
REGS1_k127_1486191_7	395494.Galf_1511	3.436e-126	415.0	COG0582@1|root,COG0582@2|Bacteria,1MXUB@1224|Proteobacteria,2VTJQ@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_1,Phage_int_SAM_2
REGS1_k127_1486191_0	522306.CAP2UW1_4386	0.0	2669.0	COG1132@1|root,COG5635@1|root,COG1132@2|Bacteria,COG5635@2|Bacteria,1MY1P@1224|Proteobacteria,2VU3B@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1486191_2	1123393.KB891326_gene20	1.306e-257	807.0	COG0210@1|root,COG1074@1|root,COG0210@2|Bacteria,COG1074@2|Bacteria,1MWW6@1224|Proteobacteria,2VM7D@28216|Betaproteobacteria,1KTI1@119069|Hydrogenophilales	119069|Hydrogenophilales	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UvrD_C
REGS1_k127_1486191_14	395494.Galf_1948	7.01e-39	146.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,44VZM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_1486191_8	395494.Galf_1945	8.689e-108	354.0	28MXA@1|root,2ZB4D@2|Bacteria,1R8JI@1224|Proteobacteria,2W45A@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1486191_27	1121091.AUMP01000045_gene787	2.376e-13	73.0	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4HZRC@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_1486191_28	589865.DaAHT2_1402	5.811e-12	68.0	2DNER@1|root,32X4S@2|Bacteria,1NB0B@1224|Proteobacteria	1224|Proteobacteria	S	ParD-like antitoxin of type II bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ParD_like
REGS1_k127_1486191_15	177437.HRM2_25470	1.136e-34	135.0	COG2026@1|root,COG2026@2|Bacteria,1N07K@1224|Proteobacteria,42V8I@68525|delta/epsilon subdivisions,2WS41@28221|Deltaproteobacteria,2MP6T@213118|Desulfobacterales	28221|Deltaproteobacteria	DJ	ParE-like toxin of type II bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ParE-like_toxin
REGS1_k127_1486191_21	497321.C664_05421	1.348e-19	89.0	2EK34@1|root,33DTI@2|Bacteria,1NGT0@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
REGS1_k127_1486191_23	395494.Galf_0854	5.576e-18	85.0	COG4190@1|root,COG4190@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
REGS1_k127_1486191_24	290315.Clim_0655	2.177e-16	80.0	COG3093@1|root,COG3093@2|Bacteria,1FFJY@1090|Chlorobi	1090|Chlorobi	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
REGS1_k127_1486191_9	395494.Galf_1465	3.635e-106	347.0	COG4974@1|root,COG4974@2|Bacteria,1R6F9@1224|Proteobacteria,2W3AX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM integrase family protein	-	-	-	ko:K07357,ko:K07358	-	-	-	-	ko00000	-	-	-	Phage_integrase
REGS1_k127_1486191_6	439235.Dalk_4800	2.365e-129	430.0	COG2251@1|root,COG2251@2|Bacteria,1QUUG@1224|Proteobacteria,43CSJ@68525|delta/epsilon subdivisions,2X807@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function(DUF2779)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2779
REGS1_k127_1486191_19	395494.Galf_1448	1.502e-21	99.0	COG2771@1|root,COG2771@2|Bacteria,1N6UR@1224|Proteobacteria,2WGVQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K18304	ko02024,ko02025,map02024,map02025	M00644,M00769	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Autoind_bind,GerE
REGS1_k127_1486191_30	1437882.AZRU01000027_gene842	1.258e-10	76.0	COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,1RMZW@1236|Gammaproteobacteria,1YHF1@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	Q	von willebrand factor, type A	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,VCBS
REGS1_k127_1486191_5	715451.ambt_03875	1.142e-129	458.0	COG2911@1|root,COG3209@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,1R1M5@1224|Proteobacteria,1RQBW@1236|Gammaproteobacteria,465Y0@72275|Alteromonadaceae	1236|Gammaproteobacteria	A	Protein conserved in bacteria	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	-
REGS1_k127_1502439_2	580332.Slit_2319	8.395e-67	229.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2VIV3@28216|Betaproteobacteria,44VP9@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
REGS1_k127_1502439_0	580332.Slit_0649	2.361e-143	458.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,44VB2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma-70 factor, region 1.2	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
REGS1_k127_1502439_3	580332.Slit_0648	2.779e-66	228.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,44W0U@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
REGS1_k127_1502439_1	580332.Slit_0647	6.217e-120	386.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,44VQB@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
REGS1_k127_1544025_9	1502770.JQMG01000001_gene2088	2.345e-83	279.0	COG1087@1|root,COG1087@2|Bacteria,1QYRM@1224|Proteobacteria,2WHYI@28216|Betaproteobacteria	28216|Betaproteobacteria	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1544025_6	1485544.JQKP01000002_gene1524	2.145e-98	337.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_1544025_2	580332.Slit_2871	8.418e-144	460.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,44VCX@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
REGS1_k127_1544025_7	709032.Sulku_2137	4.212e-90	321.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42YQC@68525|delta/epsilon subdivisions,2YRKN@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
REGS1_k127_1544025_10	1121035.AUCH01000002_gene1549	4.271e-44	163.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
REGS1_k127_1544025_5	580332.Slit_0038	1.095e-100	347.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,44V31@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
REGS1_k127_1544025_0	395494.Galf_0153	1.017e-247	767.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,44V4H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_1544025_8	580332.Slit_0040	3.999e-86	289.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,44VTH@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
REGS1_k127_1544025_1	580332.Slit_0041	1.897e-165	524.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,44V55@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
REGS1_k127_1544025_4	580332.Slit_0042	3.839e-137	439.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,44V3F@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
REGS1_k127_1544025_3	395494.Galf_0147	1.661e-139	449.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,44V0P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
REGS1_k127_1546716_4	580332.Slit_2060	2.416e-61	213.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,44V1X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
REGS1_k127_1546716_0	580332.Slit_2061	0.0	1023.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,44VC3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
REGS1_k127_1546716_2	580332.Slit_2062	5.842e-149	475.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,44VG3@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
REGS1_k127_1546716_1	580332.Slit_2063	7.136e-213	662.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VH85@28216|Betaproteobacteria,44VHR@713636|Nitrosomonadales	28216|Betaproteobacteria	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
REGS1_k127_1546716_3	580332.Slit_2064	5.321e-110	357.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,44V48@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_1550392_4	580332.Slit_0715	3.109e-18	89.0	28RKJ@1|root,2ZDZE@2|Bacteria,1P9QH@1224|Proteobacteria,2W6JD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1550392_3	580332.Slit_1880	2.656e-61	215.0	2ED3M@1|root,3370H@2|Bacteria,1NB6I@1224|Proteobacteria,2VWPI@28216|Betaproteobacteria,44W2P@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1550392_1	1485544.JQKP01000001_gene973	2.632e-91	304.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,44VNG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_1550392_0	1217648.F933_02573	3.273e-214	676.0	COG1012@1|root,COG1012@2|Bacteria,1MVGW@1224|Proteobacteria,1RN53@1236|Gammaproteobacteria,3NJP9@468|Moraxellaceae	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	calB	-	1.2.1.68	ko:K00154	-	-	-	-	ko00000,ko01000	-	-	-	Aldedh
REGS1_k127_1550392_2	395494.Galf_2655	1.269e-76	259.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,44VSW@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_1578307_2	580332.Slit_1006	6.038e-108	353.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,44UZW@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
REGS1_k127_1578307_1	580332.Slit_1007	1.707e-211	660.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,44VGK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
REGS1_k127_1578307_5	580332.Slit_1008	2.491e-43	158.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,44VZX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
REGS1_k127_1578307_4	580332.Slit_1009	1.347e-52	186.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,44VX7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
REGS1_k127_1578307_0	580332.Slit_1010	2.882e-264	816.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,44VCZ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
REGS1_k127_1578307_3	580332.Slit_1011	1.083e-65	225.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,44VWK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_1642461_7	580332.Slit_0426	1.052e-26	112.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
REGS1_k127_1642461_0	580332.Slit_0350	5.512e-214	669.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,2VJR3@28216|Betaproteobacteria,44W7Z@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	fabB	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_1642461_2	580332.Slit_0351	1.865e-130	421.0	COG0304@1|root,COG0304@2|Bacteria,1NP8M@1224|Proteobacteria,2VJDN@28216|Betaproteobacteria,44W98@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2
REGS1_k127_1642461_6	402626.Rpic_0301	2.188e-36	147.0	COG4706@1|root,COG4706@2|Bacteria,1RIH4@1224|Proteobacteria,2VT0K@28216|Betaproteobacteria,1K7TQ@119060|Burkholderiaceae	28216|Betaproteobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1642461_3	1485544.JQKP01000003_gene225	6.608e-125	405.0	COG1028@1|root,COG1028@2|Bacteria,1MUPY@1224|Proteobacteria,2VK19@28216|Betaproteobacteria,44W6C@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	KR domain	fabG2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
REGS1_k127_1642461_4	580332.Slit_0354	1.185e-40	152.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,2VWKA@28216|Betaproteobacteria,44WMD@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_1642461_5	580332.Slit_0355	1.704e-40	152.0	COG0236@1|root,COG0236@2|Bacteria,1NEMA@1224|Proteobacteria,2VW0X@28216|Betaproteobacteria,44WHU@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_1642461_1	580332.Slit_0356	7.394e-152	487.0	COG0304@1|root,COG0304@2|Bacteria,1R6NI@1224|Proteobacteria,2VN43@28216|Betaproteobacteria,44WC0@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_1642461_8	580332.Slit_0357	1.08e-09	63.0	2CXZK@1|root,32T31@2|Bacteria,1N3V0@1224|Proteobacteria,2VUNI@28216|Betaproteobacteria,44WGY@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1653037_5	1265503.KB905161_gene3344	4.954e-24	110.0	COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1SZT1@1236|Gammaproteobacteria,2Q7XM@267889|Colwelliaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
REGS1_k127_1653037_1	580332.Slit_1401	1.134e-114	376.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,44VIT@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
REGS1_k127_1653037_0	580332.Slit_1402	4.129e-232	722.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,44V56@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
REGS1_k127_1653037_4	1390370.O203_23930	9.804e-43	166.0	2937U@1|root,2ZQQR@2|Bacteria,1P5NC@1224|Proteobacteria,1SU2U@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1653037_3	864069.MicloDRAFT_00063120	9.692e-44	162.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2UEUU@28211|Alphaproteobacteria,1JY2Z@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
REGS1_k127_1653037_6	1123399.AQVE01000001_gene654	3.779e-21	95.0	COG4456@1|root,COG4456@2|Bacteria	2|Bacteria	-	-	vapB1	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
REGS1_k127_1653037_2	580332.Slit_0497	1.421e-63	221.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,44VBF@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Type II secretion system F domain	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
REGS1_k127_1695946_1	580332.Slit_2689	1.856e-98	323.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,2VJM6@28216|Betaproteobacteria,44VMX@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_1695946_0	580332.Slit_2687	1.364e-120	390.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,2VHYN@28216|Betaproteobacteria,44VCV@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_1695946_2	580332.Slit_2685	2.421e-92	308.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,44V3G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
REGS1_k127_1712892_9	580332.Slit_1452	1.78e-151	481.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,44VEC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
REGS1_k127_1712892_13	395494.Galf_1707	8.324e-56	199.0	COG0346@1|root,COG0346@2|Bacteria,1PVYI@1224|Proteobacteria,2VVCZ@28216|Betaproteobacteria,44VXU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_1712892_6	580332.Slit_1454	9.333e-198	620.0	COG1485@1|root,COG1485@2|Bacteria,1MUUW@1224|Proteobacteria,2VHQX@28216|Betaproteobacteria,44W5R@713636|Nitrosomonadales	28216|Betaproteobacteria	S	AFG1-like ATPase	yhcM	-	-	ko:K06916	-	-	-	-	ko00000,ko03036	-	-	-	AFG1_ATPase
REGS1_k127_1712892_8	580332.Slit_1457	7.049e-188	597.0	COG0667@1|root,COG0667@2|Bacteria,1MV2Y@1224|Proteobacteria,2VI7D@28216|Betaproteobacteria,44V9C@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM aldo keto reductase	tas	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_1712892_7	580332.Slit_1459	3.994e-188	593.0	COG3287@1|root,COG3287@2|Bacteria,1R825@1224|Proteobacteria,2VPKS@28216|Betaproteobacteria,44W6E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	FIST_C	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
REGS1_k127_1712892_2	580332.Slit_1460	0.0	1101.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W78@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS,PAS_9,dCache_2
REGS1_k127_1712892_5	395494.Galf_0102	1.788e-243	793.0	COG2202@1|root,COG5000@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_4,PAS_9,dCache_1
REGS1_k127_1712892_1	395494.Galf_1313	0.0	1197.0	COG3221@1|root,COG5001@1|root,COG3221@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VZNB@28216|Betaproteobacteria,44W9B@713636|Nitrosomonadales	28216|Betaproteobacteria	T	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_8,Phosphonate-bd
REGS1_k127_1712892_11	580332.Slit_1461	3.655e-86	285.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,44VQN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
REGS1_k127_1712892_0	580332.Slit_1462	0.0	1840.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,44V0B@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
REGS1_k127_1712892_4	580332.Slit_1465	2.585e-293	903.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,44VBE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
REGS1_k127_1712892_3	580332.Slit_1466	0.0	1041.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,44V7R@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
REGS1_k127_1712892_10	580332.Slit_1447	1.242e-141	454.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2WHYC@28216|Betaproteobacteria,44WNC@713636|Nitrosomonadales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
REGS1_k127_1721269_8	580332.Slit_2290	0.0002146	51.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,44VGM@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
REGS1_k127_1721269_7	395494.Galf_2202	2.507e-21	98.0	COG1918@1|root,COG1918@2|Bacteria,1NA6D@1224|Proteobacteria,2VY9N@28216|Betaproteobacteria,44W2B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
REGS1_k127_1721269_0	580332.Slit_2292	6.717e-319	985.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,2VIRG@28216|Betaproteobacteria,44VA4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
REGS1_k127_1721269_1	580332.Slit_2295	5.982e-109	359.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,2VKZV@28216|Betaproteobacteria,44VNR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	-	-	-	ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
REGS1_k127_1721269_4	580332.Slit_2322	6.98e-52	185.0	COG0640@1|root,COG0640@2|Bacteria,1RH5P@1224|Proteobacteria,2VU68@28216|Betaproteobacteria	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
REGS1_k127_1721269_6	1340493.JNIF01000003_gene3430	2.34e-26	110.0	2E5NA@1|root,330D3@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4287)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4287
REGS1_k127_1721269_2	580332.Slit_2325	5.013e-60	209.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria,44WGC@713636|Nitrosomonadales	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_1736555_5	580332.Slit_2081	3.958e-96	316.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2WAJ5@28216|Betaproteobacteria,44VDR@713636|Nitrosomonadales	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
REGS1_k127_1736555_2	580332.Slit_2080	9.772e-193	608.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
REGS1_k127_1736555_4	580332.Slit_2079	9.755e-124	400.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria,44VNJ@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_1736555_0	580332.Slit_2078	8.283e-225	705.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_1736555_1	580332.Slit_2077	8.658e-225	700.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,44UZP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_1736555_3	395494.Galf_1543	5.063e-137	440.0	COG2961@1|root,COG2961@2|Bacteria,1MWGA@1224|Proteobacteria,2VHM4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Specifically methylates the adenine in position 2030 of 23S rRNA	rlmJ	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
REGS1_k127_1736555_6	395494.Galf_1434	1.946e-46	172.0	COG0845@1|root,COG0845@2|Bacteria,1MUI8@1224|Proteobacteria,2VIAA@28216|Betaproteobacteria,44W4P@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM type I secretion membrane fusion protein, HlyD family	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
REGS1_k127_1737426_8	580332.Slit_2411	3e-70	240.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria,44VZ8@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DNA polymerase III chi subunit HolC	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
REGS1_k127_1737426_11	1123354.AUDR01000016_gene1353	1.369e-36	142.0	COG1708@1|root,COG1708@2|Bacteria,1QAUR@1224|Proteobacteria,2VX91@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
REGS1_k127_1737426_9	443144.GM21_2646	7.372e-59	207.0	COG1708@1|root,COG1708@2|Bacteria,1N97U@1224|Proteobacteria	1224|Proteobacteria	S	nucleotidyltransferase substrate binding protein, HI0074 family	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2,NTase_sub_bind
REGS1_k127_1737426_1	580332.Slit_2410	3.591e-278	860.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,44V6F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
REGS1_k127_1737426_3	580332.Slit_2409	5.171e-169	548.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,44V0Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
REGS1_k127_1737426_4	580332.Slit_2408	6.719e-161	513.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria,44UYI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
REGS1_k127_1737426_10	580332.Slit_2407	3.225e-37	144.0	2E3UK@1|root,32YRY@2|Bacteria,1PSPV@1224|Proteobacteria,2WAA7@28216|Betaproteobacteria,44W36@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
REGS1_k127_1737426_5	580332.Slit_2405	2.022e-86	291.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,44VVF@713636|Nitrosomonadales	28216|Betaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_1737426_0	580332.Slit_2404	0.0	1043.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,44V6P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM thiamine pyrophosphate	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
REGS1_k127_1737426_6	580332.Slit_2403	2.762e-85	286.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,44VPP@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
REGS1_k127_1737426_2	580332.Slit_2402	5.926e-213	662.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,44V1V@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
REGS1_k127_1737426_7	580332.Slit_2401	3.573e-81	271.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
REGS1_k127_1744808_4	580332.Slit_2848	4.185e-57	201.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,44VZ0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
REGS1_k127_1744808_1	580332.Slit_2849	1.457e-187	589.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,44VB7@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
REGS1_k127_1744808_6	580332.Slit_2850	2.724e-45	171.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,44VZ7@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
REGS1_k127_1744808_0	580332.Slit_2851	8.829e-305	942.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,44VF5@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
REGS1_k127_1744808_2	580332.Slit_2853	9.867e-79	264.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,44VUG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
REGS1_k127_1744808_3	580332.Slit_2854	6.752e-68	234.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,44VSU@713636|Nitrosomonadales	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
REGS1_k127_1744808_5	580332.Slit_2856	1.436e-56	198.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,44VMS@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
REGS1_k127_180993_1	580332.Slit_1663	0.0	1044.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,44VJV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
REGS1_k127_180993_4	580332.Slit_1662	2.64e-158	502.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,44VG0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Metallopeptidase family M24	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
REGS1_k127_180993_2	580332.Slit_1660	5.924e-264	819.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VC4@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
REGS1_k127_180993_5	580332.Slit_1659	3.695e-148	473.0	COG3221@1|root,COG3221@2|Bacteria,1MX7I@1224|Proteobacteria,2VP4Q@28216|Betaproteobacteria,44VB1@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_180993_3	580332.Slit_1658	1.45e-262	819.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHIC@28216|Betaproteobacteria,44WDC@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_3,PAS_4,sCache_3_2
REGS1_k127_180993_0	1485544.JQKP01000010_gene837	0.0	1086.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,44VEJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
REGS1_k127_180993_6	580332.Slit_1657	2.513e-32	126.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,44V6R@713636|Nitrosomonadales	28216|Betaproteobacteria	T	elongation factor Tu domain 2 protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_1839100_3	580332.Slit_2953	4.526e-47	169.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,44VMC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
REGS1_k127_1839100_2	580332.Slit_0170	3.109e-76	270.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	DUF1573,OmpA,OmpA_membrane,PsaA_PsaB,TSP_3
REGS1_k127_1839100_0	1485544.JQKP01000001_gene1063	2.954e-192	611.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1Q94S@1224|Proteobacteria,2VIVY@28216|Betaproteobacteria,44W9I@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8,Pkinase,Pkinase_Tyr
REGS1_k127_1839100_4	580332.Slit_2955	1.543e-41	154.0	COG5626@1|root,COG5626@2|Bacteria,1N8QB@1224|Proteobacteria,2VWJM@28216|Betaproteobacteria,44W22@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
REGS1_k127_1839100_1	580332.Slit_2956	6.198e-99	326.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,44VMU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
REGS1_k127_1839100_5	866536.Belba_2373	1.428e-20	95.0	COG3668@1|root,COG3668@2|Bacteria	2|Bacteria	D	Plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_1844710_3	1485544.JQKP01000020_gene55	1.095e-34	132.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,44V8V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	rmlA	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
REGS1_k127_1844710_1	580332.Slit_0046	5.684e-200	625.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,44VMI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
REGS1_k127_1844710_0	580332.Slit_0045	1.577e-276	880.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,44V59@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
REGS1_k127_1844710_2	580332.Slit_0044	9.104e-188	595.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,44VEF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
REGS1_k127_1844710_4	580332.Slit_0043	2.87e-15	78.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,44V0P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
REGS1_k127_1845667_3	580332.Slit_0538	1.58e-27	114.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,44W47@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
REGS1_k127_1845667_1	580332.Slit_0537	1.489e-271	844.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,1MV37@1224|Proteobacteria,2VJ21@28216|Betaproteobacteria,44W5N@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
REGS1_k127_1845667_0	580332.Slit_0536	0.0	1442.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44VNC@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GAF,T2SSE,T2SSE_N
REGS1_k127_1845667_2	580332.Slit_0535	1.968e-123	398.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,2VQGZ@28216|Betaproteobacteria	28216|Betaproteobacteria	PT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
REGS1_k127_1858946_1	580332.Slit_1850	6.96e-184	577.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,44VHW@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_1858946_4	338969.Rfer_0025	1.164e-71	250.0	COG4849@1|root,COG4849@2|Bacteria,1RDHG@1224|Proteobacteria,2VVB8@28216|Betaproteobacteria,4AF0B@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1858946_5	1116472.MGMO_86c00200	2.898e-42	161.0	28W7P@1|root,2ZI89@2|Bacteria,1N2SJ@1224|Proteobacteria,1SA34@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1858946_2	1485544.JQKP01000015_gene2101	6.986e-181	570.0	COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,2VJU6@28216|Betaproteobacteria,44WHT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
REGS1_k127_1858946_3	1132855.KB913035_gene571	2.41e-79	277.0	2DPCB@1|root,331HJ@2|Bacteria,1NED4@1224|Proteobacteria,2W5J1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
REGS1_k127_1858946_0	580332.Slit_1856	0.0	1514.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VHS7@28216|Betaproteobacteria,44V1M@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
REGS1_k127_1858946_6	338969.Rfer_2706	2.258e-18	85.0	COG2067@1|root,COG2067@2|Bacteria,1MUU4@1224|Proteobacteria,2VHI3@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Outer membrane protein transport protein, Ompp1 FadL TodX	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
REGS1_k127_194126_7	580332.Slit_1505	5.388e-38	142.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,44VNW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
REGS1_k127_194126_2	580332.Slit_1504	1.702e-204	644.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
REGS1_k127_194126_3	580332.Slit_1503	1.027e-192	606.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria,44VCA@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_194126_4	580332.Slit_1502	4.054e-172	550.0	2CG46@1|root,2Z7W3@2|Bacteria,1NFW3@1224|Proteobacteria,2VN3X@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_194126_5	279714.FuraDRAFT_0305	1.203e-58	211.0	28KTK@1|root,2ZAAP@2|Bacteria,1RCI8@1224|Proteobacteria,2VQ6W@28216|Betaproteobacteria,2KQZ8@206351|Neisseriales	206351|Neisseriales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_194126_0	580332.Slit_1500	0.0	1394.0	COG1196@1|root,COG1196@2|Bacteria,1NGZ2@1224|Proteobacteria,2VIWY@28216|Betaproteobacteria	28216|Betaproteobacteria	D	SMC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_29,SMC_N
REGS1_k127_194126_6	864073.HFRIS_021441	7.544e-47	184.0	2DZNC@1|root,32VEI@2|Bacteria,1N426@1224|Proteobacteria,2VVJB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function C-terminus (DUF2399)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2399
REGS1_k127_194126_1	580332.Slit_1499	3.23e-297	915.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,44V4E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM tRNA synthetase class II (D K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
REGS1_k127_195348_0	580332.Slit_2103	2.125e-281	868.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,44VM0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
REGS1_k127_195348_4	755731.Clo1100_3397	1.283e-92	307.0	COG1403@1|root,COG1403@2|Bacteria,1UUDX@1239|Firmicutes,256GS@186801|Clostridia	186801|Clostridia	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_195348_3	232721.Ajs_4252	2.156e-148	475.0	COG0270@1|root,COG0270@2|Bacteria,1MV9H@1224|Proteobacteria,2VIFH@28216|Betaproteobacteria,4AFP0@80864|Comamonadaceae	28216|Betaproteobacteria	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
REGS1_k127_195348_6	395494.Galf_0509	4.101e-60	213.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,44VWH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
REGS1_k127_195348_2	1485544.JQKP01000014_gene1886	3.683e-189	597.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,44V3M@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
REGS1_k127_195348_5	580332.Slit_2106	2.887e-80	276.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,44VUA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
REGS1_k127_195348_1	580332.Slit_2107	1.575e-233	724.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,44VB6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_195348_7	215803.DB30_4135	5.873e-51	187.0	COG2808@1|root,COG2808@2|Bacteria,1N1B9@1224|Proteobacteria,42WNY@68525|delta/epsilon subdivisions,2WRMA@28221|Deltaproteobacteria,2Z050@29|Myxococcales	28221|Deltaproteobacteria	K	Putative FMN-binding domain	paiB	-	-	ko:K07734	-	-	-	-	ko00000,ko03000	-	-	-	FMN_bind_2
REGS1_k127_1993445_3	580332.Slit_1512	7.375e-116	374.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,2VH1Z@28216|Betaproteobacteria,44V0V@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
REGS1_k127_1993445_1	580332.Slit_1514	5.126e-202	636.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VH8N@28216|Betaproteobacteria,44V3E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
REGS1_k127_1993445_4	580332.Slit_1515	2.336e-113	367.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,2VHT5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LemA Family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
REGS1_k127_1993445_6	580332.Slit_1516	1.152e-63	227.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
REGS1_k127_1993445_2	580332.Slit_1516	6.704e-117	382.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria	28216|Betaproteobacteria	S	COG1512 Beta-propeller domains of methanol dehydrogenase type	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
REGS1_k127_1993445_5	580332.Slit_1517	2.293e-82	275.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2VRJE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
REGS1_k127_1993445_0	580332.Slit_1518	3.402e-253	787.0	COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,1MY43@1224|Proteobacteria,2VM3G@28216|Betaproteobacteria,44W8Z@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD,CYTH
REGS1_k127_2016011_1	395494.Galf_1605	7.098e-138	446.0	COG1181@1|root,COG1181@2|Bacteria,1QWAW@1224|Proteobacteria,2VITI@28216|Betaproteobacteria,44W75@713636|Nitrosomonadales	28216|Betaproteobacteria	M	RimK-like ATP-grasp domain	cphA2	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK
REGS1_k127_2016011_0	395494.Galf_1604	7.76e-250	778.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,2VJMQ@28216|Betaproteobacteria,44WAI@713636|Nitrosomonadales	28216|Betaproteobacteria	HJM	RimK-like ATP-grasp domain	cphA1	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
REGS1_k127_2310640_2	580332.Slit_1427	1.194e-255	791.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,44UYF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
REGS1_k127_2310640_0	580332.Slit_1426	7.744e-280	861.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,44VE3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
REGS1_k127_2310640_7	580332.Slit_1425	1.459e-191	603.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,44V4A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
REGS1_k127_2310640_13	580332.Slit_1424	1.767e-21	95.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,44WN4@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
REGS1_k127_2310640_9	580332.Slit_1423	1.625e-147	471.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,44VKJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
REGS1_k127_2310640_6	580332.Slit_1422	1.42e-193	610.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,44VCI@713636|Nitrosomonadales	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
REGS1_k127_2310640_5	580332.Slit_1421	6.056e-211	659.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,44V2X@713636|Nitrosomonadales	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
REGS1_k127_2310640_12	580332.Slit_1420	4.175e-40	149.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,44VYC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
REGS1_k127_2310640_14	640081.Dsui_0493	6.341e-20	98.0	2EFF1@1|root,3397W@2|Bacteria,1N9PW@1224|Proteobacteria,2VX4Q@28216|Betaproteobacteria,2KXE8@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2310640_1	580332.Slit_1418	5.445e-272	840.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,44V5G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
REGS1_k127_2310640_8	580332.Slit_1417	6.031e-179	567.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,44VFV@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
REGS1_k127_2310640_10	580332.Slit_1416	2.207e-99	327.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,44VUI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
REGS1_k127_2310640_3	580332.Slit_1415	3.343e-253	784.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,44VJ4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
REGS1_k127_2310640_4	580332.Slit_1414	8.981e-238	739.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,44VKE@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
REGS1_k127_2310640_11	580332.Slit_1413	6.819e-54	202.0	COG1426@1|root,COG3266@1|root,COG1426@2|Bacteria,COG3266@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,44VYD@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
REGS1_k127_2310640_16	580332.Slit_1412	8.834e-07	50.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,44VS2@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
REGS1_k127_2347787_4	395494.Galf_2272	1.345e-70	239.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,44VG4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
REGS1_k127_2347787_2	580332.Slit_0702	3.53e-143	458.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,44V07@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
REGS1_k127_2347787_5	580332.Slit_0701	2.701e-56	211.0	2CU7M@1|root,32SUS@2|Bacteria,1N1WF@1224|Proteobacteria,2VUS0@28216|Betaproteobacteria,44VVW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
REGS1_k127_2347787_7	580332.Slit_0699	3.101e-26	108.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,44W27@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
REGS1_k127_2347787_6	580332.Slit_0698	9.739e-43	157.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,44W1P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
REGS1_k127_2347787_1	580332.Slit_0697	4.247e-245	760.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,44V4T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
REGS1_k127_2347787_3	580332.Slit_0696	2.057e-121	391.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,44V3X@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
REGS1_k127_2347787_0	580332.Slit_0695	1.588e-247	767.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,44VFJ@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
REGS1_k127_2347787_9	1144319.PMI16_02332	1.529e-06	50.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,2VXUB@28216|Betaproteobacteria,4750K@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	STAS domain	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
REGS1_k127_2423356_3	316067.Geob_3322	9.737e-304	948.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,42MP9@68525|delta/epsilon subdivisions,2WJWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.106,3.A.1.109,3.A.1.109.1,3.A.1.109.2,3.A.1.21	-	-	ABC_membrane,ABC_tran,Peptidase_C39
REGS1_k127_2423356_10	1454004.AW11_03578	5.711e-56	206.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria	1224|Proteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Peptidase_M23
REGS1_k127_2423356_13	1408444.JHYC01000013_gene2473	7.432e-15	77.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2423356_7	580332.Slit_1493	1.671e-92	306.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,2VQI2@28216|Betaproteobacteria,44VU9@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_2423356_2	580332.Slit_1492	0.0	1085.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,44VII@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
REGS1_k127_2423356_9	420662.Mpe_B0252	8.548e-71	247.0	COG1573@1|root,COG1573@2|Bacteria,1RBA6@1224|Proteobacteria,2VRBX@28216|Betaproteobacteria,1KP1H@119065|unclassified Burkholderiales	28216|Betaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
REGS1_k127_2423356_0	580332.Slit_1486	0.0	1297.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,2VI1P@28216|Betaproteobacteria,44V9N@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
REGS1_k127_2423356_11	580332.Slit_1485	6.666e-47	169.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,2VU1D@28216|Betaproteobacteria,44VZI@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
REGS1_k127_2423356_6	580332.Slit_1484	8.576e-163	516.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,44UZ4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
REGS1_k127_2423356_12	335283.Neut_1645	1.255e-35	139.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,373CA@32003|Nitrosomonadales	28216|Betaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
REGS1_k127_2423356_1	1485544.JQKP01000015_gene2071	0.0	1219.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,44V5A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
REGS1_k127_2423356_4	580332.Slit_1481	2.779e-291	897.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,44VCN@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
REGS1_k127_2423356_8	580332.Slit_1480	1.884e-73	251.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,44VTX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
REGS1_k127_2423356_5	1485544.JQKP01000003_gene281	3.809e-180	572.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,2VI2X@28216|Betaproteobacteria,44VQZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	IF-2B
REGS1_k127_2424810_1	580332.Slit_0281	4.07e-136	445.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VIMC@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	dctB	-	2.7.13.3	ko:K10125	ko02020,map02020	M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,dCache_1
REGS1_k127_2424810_0	1485544.JQKP01000001_gene960	1.936e-137	438.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,44V7D@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
REGS1_k127_2424810_2	1485544.JQKP01000001_gene958	7.076e-120	387.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,44V8F@713636|Nitrosomonadales	28216|Betaproteobacteria	G	HAD-hyrolase-like	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_2424810_3	580332.Slit_0278	2.464e-102	336.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,44V45@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
REGS1_k127_2445777_1	580332.Slit_2691	2.105e-136	437.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,2VJAS@28216|Betaproteobacteria,44VDS@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_2445777_0	580332.Slit_2692	5.483e-219	683.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,2VH55@28216|Betaproteobacteria,44V9D@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_2445777_3	1485544.JQKP01000002_gene1652	9.609e-43	159.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_2445777_4	1538295.JY96_04190	7.883e-19	94.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,1KM92@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Cytochrome	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C
REGS1_k127_2445777_2	580332.Slit_2695	5.076e-60	208.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria,44VQX@713636|Nitrosomonadales	28216|Betaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
REGS1_k127_2505206_1	314345.SPV1_05507	8.922e-99	329.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg
REGS1_k127_2505206_0	580332.Slit_2545	1.153e-263	816.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,44VGF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_2546732_0	686340.Metal_0256	8.079e-259	829.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
REGS1_k127_2546732_1	292415.Tbd_1838	3.565e-146	477.0	COG3746@1|root,COG3746@2|Bacteria,1R8Q0@1224|Proteobacteria,2VZAK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
REGS1_k127_2570988_6	1485544.JQKP01000002_gene1561	3.806e-19	91.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VR34@28216|Betaproteobacteria,44VSI@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Carbonic anhydrase	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
REGS1_k127_2570988_2	580332.Slit_0027	1.053e-178	562.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,2VGZK@28216|Betaproteobacteria,44VFI@713636|Nitrosomonadales	28216|Betaproteobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
REGS1_k127_2570988_5	580332.Slit_0026	3.924e-86	287.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,2VQ1I@28216|Betaproteobacteria,44VPK@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
REGS1_k127_2570988_1	395494.Galf_0037	6.644e-212	659.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,44V03@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
REGS1_k127_2570988_0	580332.Slit_0024	0.0	1324.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,44VJG@713636|Nitrosomonadales	28216|Betaproteobacteria	P	SMART von Willebrand factor type A	cbbO2	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
REGS1_k127_2570988_3	395494.Galf_0035	9.797e-159	503.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,44UZJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ATPase associated with various cellular activities AAA_5	cbbQ2	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
REGS1_k127_2570988_4	1163617.SCD_n02850	1.602e-116	375.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbM	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
REGS1_k127_2615300_5	395494.Galf_1757	3.106e-51	181.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,44W5X@713636|Nitrosomonadales	28216|Betaproteobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
REGS1_k127_2615300_2	697282.Mettu_0437	5.749e-159	512.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,1RMKB@1236|Gammaproteobacteria,1XF17@135618|Methylococcales	135618|Methylococcales	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
REGS1_k127_2615300_0	580332.Slit_0275	4.096e-321	994.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,44W7H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
REGS1_k127_2615300_3	314345.SPV1_04948	1.752e-139	466.0	COG2203@1|root,COG2206@1|root,COG3829@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1RAQS@1224|Proteobacteria	1224|Proteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HD,HD_5,PAS,PAS_4,PAS_9,Response_reg
REGS1_k127_2615300_4	580332.Slit_1327	4.401e-91	324.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,2WHFM@28216|Betaproteobacteria,44WPK@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
REGS1_k127_2615300_1	580332.Slit_0276	6.078e-190	597.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,44VJ3@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
REGS1_k127_2653077_10	261292.Nit79A3_2987	4.34e-26	109.0	COG4190@1|root,COG4190@2|Bacteria,1N3VQ@1224|Proteobacteria,2VUVX@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2653077_11	396588.Tgr7_1986	3.183e-20	93.0	2E33J@1|root,32Y3P@2|Bacteria,1N9JJ@1224|Proteobacteria,1SCAK@1236|Gammaproteobacteria,1WZDJ@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2653077_0	580332.Slit_2199	6.685e-175	557.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,44VGY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the radical SAM superfamily. RlmN family	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
REGS1_k127_2653077_1	580332.Slit_2201	2.444e-100	331.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,2VQQC@28216|Betaproteobacteria,44WFH@713636|Nitrosomonadales	28216|Betaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
REGS1_k127_2653077_7	580332.Slit_2201	8e-36	141.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,2VQQC@28216|Betaproteobacteria,44WFH@713636|Nitrosomonadales	28216|Betaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
REGS1_k127_2653077_12	375286.mma_3587	1.152e-16	85.0	2EP1T@1|root,315BD@2|Bacteria,1PVCW@1224|Proteobacteria,2WB83@28216|Betaproteobacteria,4757Y@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2653077_5	580332.Slit_2196	1.982e-43	162.0	2EJUZ@1|root,333IS@2|Bacteria,1NFIG@1224|Proteobacteria,2VWAA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative prokaryotic signal transducing protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
REGS1_k127_2653077_13	497321.C664_13719	1.654e-11	68.0	2C8AW@1|root,33ACI@2|Bacteria,1NGTZ@1224|Proteobacteria,2VXMK@28216|Betaproteobacteria,2KXIX@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2653077_4	323848.Nmul_A0727	4.117e-56	212.0	COG4585@1|root,COG4585@2|Bacteria,1N0Y7@1224|Proteobacteria,2W29U@28216|Betaproteobacteria,371M2@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
REGS1_k127_2653077_3	1131553.JIBI01000068_gene1061	2.015e-71	248.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRK9@28216|Betaproteobacteria,372UB@32003|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM Signal transduction response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_2653077_6	395494.Galf_0299	1.576e-37	144.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_2653077_9	580332.Slit_2494	6.039e-28	117.0	COG2319@1|root,COG2319@2|Bacteria,1QZ0Z@1224|Proteobacteria	1224|Proteobacteria	S	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
REGS1_k127_2653077_2	1163617.SCD_n00601	9.108e-88	294.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petA	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
REGS1_k127_2653077_8	582744.Msip34_0283	2.331e-33	130.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,2KKSW@206350|Nitrosomonadales	206350|Nitrosomonadales	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
REGS1_k127_2656489_3	28229.ND2E_0206	3.923e-77	279.0	COG1629@1|root,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,1SZT1@1236|Gammaproteobacteria,2Q7XM@267889|Colwelliaceae	1236|Gammaproteobacteria	P	TonB dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
REGS1_k127_2656489_0	395494.Galf_2548	2.217e-180	572.0	COG2890@1|root,COG2890@2|Bacteria,1MV12@1224|Proteobacteria,2VJVT@28216|Betaproteobacteria	28216|Betaproteobacteria	J	methyltransferase small	hemK1	-	-	-	-	-	-	-	-	-	-	-	MTS
REGS1_k127_2656489_2	580332.Slit_2069	9.344e-132	422.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,44UZN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
REGS1_k127_2656489_4	1163617.SCD_n01022	1.413e-69	242.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphoglycolate phosphatase	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_2656489_1	580332.Slit_2071	3.983e-161	525.0	COG2114@1|root,COG2703@1|root,COG2114@2|Bacteria,COG2703@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,44WAE@713636|Nitrosomonadales	28216|Betaproteobacteria	PT	SMART adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
REGS1_k127_2657693_12	580332.Slit_0494	1.516e-46	170.0	COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria	1224|Proteobacteria	NU	General secretion pathway protein I	gspI	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
REGS1_k127_2657693_10	580332.Slit_0493	3.298e-56	205.0	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
REGS1_k127_2657693_5	580332.Slit_0492	5.167e-109	362.0	COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,2VS9P@28216|Betaproteobacteria	28216|Betaproteobacteria	U	general secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
REGS1_k127_2657693_6	580332.Slit_0491	7.438e-107	360.0	COG3297@1|root,COG3297@2|Bacteria	2|Bacteria	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
REGS1_k127_2657693_16	580332.Slit_0490	2.291e-33	136.0	COG3149@1|root,COG3149@2|Bacteria,1NAXX@1224|Proteobacteria,2VY4T@28216|Betaproteobacteria	28216|Betaproteobacteria	U	General secretion pathway	gspM	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
REGS1_k127_2657693_15	1485544.JQKP01000005_gene334	5.624e-37	140.0	COG3617@1|root,COG3617@2|Bacteria,1QX1C@1224|Proteobacteria,2WIF0@28216|Betaproteobacteria	28216|Betaproteobacteria	K	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
REGS1_k127_2657693_13	1454004.AW11_01193	1.581e-44	180.0	COG1864@1|root,COG2931@1|root,COG3179@1|root,COG3209@1|root,COG3391@1|root,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3179@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,1RC1P@1224|Proteobacteria,2VUZC@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19
REGS1_k127_2657693_7	580332.Slit_1403	1.591e-97	328.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria,44VSA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
REGS1_k127_2657693_0	580332.Slit_1404	2.707e-250	781.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria,1R6J6@1224|Proteobacteria,2VPCU@28216|Betaproteobacteria,44W84@713636|Nitrosomonadales	28216|Betaproteobacteria	MT	MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
REGS1_k127_2657693_14	199310.c0222	1.299e-37	154.0	2E33Z@1|root,32Y42@2|Bacteria,1NDBD@1224|Proteobacteria,1SNMD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2657693_2	580332.Slit_1406	2.294e-198	626.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,44UY8@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
REGS1_k127_2657693_3	580332.Slit_1407	4.354e-190	596.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,2VHPJ@28216|Betaproteobacteria,44W99@713636|Nitrosomonadales	28216|Betaproteobacteria	G	TIGRFAM TRAP dicarboxylate transporter, DctP subunit	dctP	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
REGS1_k127_2657693_8	580332.Slit_1408	4.092e-94	310.0	COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,2VQMP@28216|Betaproteobacteria,44WFI@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM Tripartite ATP-independent periplasmic transporter DctQ component	dctQ	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
REGS1_k127_2657693_1	580332.Slit_1409	2.01e-247	767.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VHJP@28216|Betaproteobacteria,44W7G@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	dctM	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
REGS1_k127_2657693_9	395494.Galf_1398	1.019e-78	264.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,44VQP@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
REGS1_k127_2657693_4	580332.Slit_1411	3.465e-180	565.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,44V7I@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
REGS1_k127_26713_4	580332.Slit_2713	2.051e-29	117.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,44VGJ@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
REGS1_k127_26713_1	580332.Slit_2712	2.294e-182	577.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,44V9K@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
REGS1_k127_26713_5	395494.Galf_0342	4.356e-12	68.0	2AG2M@1|root,3166Z@2|Bacteria,1PWZE@1224|Proteobacteria,2WCHD@28216|Betaproteobacteria,44W3K@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_26713_3	580332.Slit_2710	2.53e-38	148.0	COG4701@1|root,COG4701@2|Bacteria,1N8HR@1224|Proteobacteria,2VW5Y@28216|Betaproteobacteria,44W40@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
REGS1_k127_26713_2	580332.Slit_2709	2.009e-134	434.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,44WCE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
REGS1_k127_26713_0	580332.Slit_2708	0.0	1582.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,44V1H@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
REGS1_k127_26713_6	580332.Slit_2707	3.873e-08	55.0	COG0664@1|root,COG0664@2|Bacteria,1NBRS@1224|Proteobacteria,2WCFJ@28216|Betaproteobacteria,44VZA@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_2692152_2	395494.Galf_2724	1.118e-28	124.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VKX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
REGS1_k127_2692152_1	395494.Galf_2722	1.992e-61	219.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2692152_3	296591.Bpro_1181	4.336e-21	97.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2692152_0	395494.Galf_2724	0.0	1060.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VKX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
REGS1_k127_2709999_4	1485544.JQKP01000001_gene1144	1.536e-98	325.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,2WAP5@28216|Betaproteobacteria,44WER@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
REGS1_k127_2709999_8	398579.Spea_2747	3.926e-40	158.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,1RSJI@1236|Gammaproteobacteria,2QDTN@267890|Shewanellaceae	1236|Gammaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GGDEF
REGS1_k127_2709999_11	349521.HCH_05560	1.945e-11	70.0	COG0596@1|root,COG0596@2|Bacteria,1MUSF@1224|Proteobacteria,1RZNC@1236|Gammaproteobacteria,1XPMR@135619|Oceanospirillales	135619|Oceanospirillales	L	Alpha beta hydrolase superfamily	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
REGS1_k127_2709999_10	580332.Slit_2267	8.604e-32	124.0	COG4728@1|root,COG4728@2|Bacteria,1NEUX@1224|Proteobacteria,2VX3S@28216|Betaproteobacteria,44W2S@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
REGS1_k127_2709999_7	580332.Slit_2266	9.37e-51	183.0	2CHAX@1|root,32ZC9@2|Bacteria,1N6X2@1224|Proteobacteria,2VW2I@28216|Betaproteobacteria,44W1M@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3301)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3301
REGS1_k127_2709999_5	290317.Cpha266_0793	1.687e-93	310.0	COG2201@1|root,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	cheB	-	2.1.1.80,3.1.1.61,3.5.1.44	ko:K03412,ko:K03413,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_9,Response_reg
REGS1_k127_2709999_3	497964.CfE428DRAFT_1677	1.084e-111	368.0	COG3315@1|root,COG3315@2|Bacteria	2|Bacteria	Q	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
REGS1_k127_2709999_9	1121381.JNIV01000015_gene1695	1.706e-36	148.0	COG0177@1|root,COG0177@2|Bacteria	2|Bacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
REGS1_k127_2709999_6	1121935.AQXX01000080_gene858	2.229e-81	281.0	COG3279@1|root,COG3279@2|Bacteria,1NH0K@1224|Proteobacteria,1SUCS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2709999_1	1207075.PputUW4_04190	3.258e-220	709.0	COG0323@1|root,COG4191@1|root,COG0323@2|Bacteria,COG4191@2|Bacteria,1ND4X@1224|Proteobacteria,1RQA7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_3
REGS1_k127_2709999_2	525257.HMPREF0204_11710	2.26e-115	385.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes,1HZAK@117743|Flavobacteriia,3ZSNS@59732|Chryseobacterium	976|Bacteroidetes	L	C-5 cytosine-specific DNA methylase	dcm	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,Eco57I
REGS1_k127_2709999_0	580332.Slit_2262	3.357e-266	825.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,44V6H@713636|Nitrosomonadales	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
REGS1_k127_2711672_1	580332.Slit_1198	5.493e-189	594.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,44W68@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
REGS1_k127_2711672_0	580332.Slit_2154	0.0	1305.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria,44W4Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
REGS1_k127_2711672_5	580332.Slit_2155	7.892e-51	184.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
REGS1_k127_2711672_3	580332.Slit_2156	5.108e-96	318.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,44WFC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2711672_6	395494.Galf_1373	4.465e-16	81.0	2EIC1@1|root,33C3D@2|Bacteria,1NHMH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
REGS1_k127_2711672_2	580332.Slit_1204	2.518e-101	332.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,44VKR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_2755902_0	580332.Slit_0333	5.04e-280	866.0	COG0247@1|root,COG0277@1|root,COG0479@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG0479@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,44VCD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF3400)	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
REGS1_k127_2755902_4	580332.Slit_0334	3.165e-72	249.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,44WH9@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
REGS1_k127_2755902_1	1123487.KB892834_gene2793	4.492e-114	376.0	COG0598@1|root,COG0598@2|Bacteria,1MWMP@1224|Proteobacteria,2VHH3@28216|Betaproteobacteria,2M014@206389|Rhodocyclales	206389|Rhodocyclales	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
REGS1_k127_2755902_2	1121403.AUCV01000015_gene4697	2.42e-100	342.0	2DN4D@1|root,32VFV@2|Bacteria,1N32J@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2755902_3	580332.Slit_1599	7.734e-99	343.0	COG0739@1|root,COG2931@1|root,COG0739@2|Bacteria,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria,2VHFJ@28216|Betaproteobacteria,44W46@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Hemolysin-type calcium-binding region	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_66,HCBP_related,He_PIG,HemolysinCabind
REGS1_k127_2755902_5	580332.Slit_0336	8.776e-68	231.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,2VJPP@28216|Betaproteobacteria,44V5M@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeB	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
REGS1_k127_276843_0	338969.Rfer_0396	2.613e-187	589.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria,4AGJH@80864|Comamonadaceae	28216|Betaproteobacteria	C	Radical SAM superfamily	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_276843_5	580332.Slit_2177	1.423e-79	269.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2VT5I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
REGS1_k127_276843_1	1485544.JQKP01000004_gene521	1.95e-164	527.0	COG1075@1|root,COG1075@2|Bacteria,1NM55@1224|Proteobacteria,2VNDC@28216|Betaproteobacteria,44W8R@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Alpha/beta hydrolase of unknown function (DUF900)	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_276843_7	580332.Slit_2296	4.261e-49	177.0	2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,2WCFP@28216|Betaproteobacteria,44VZH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM HopJ type III effector protein	-	-	-	-	-	-	-	-	-	-	-	-	HopJ
REGS1_k127_276843_2	580332.Slit_0020	2.274e-155	494.0	COG0697@1|root,COG0697@2|Bacteria,1NEYM@1224|Proteobacteria,2VPAG@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	permeases of the drug metabolite transporter (Dmt) superfamily	yijE_2	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_276843_6	709797.CSIRO_0311	3.229e-50	186.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,2U71S@28211|Alphaproteobacteria,3JUB2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
REGS1_k127_276843_8	1122963.AUHB01000005_gene2668	1.366e-43	164.0	COG4319@1|root,COG4319@2|Bacteria,1N8K3@1224|Proteobacteria,2UXUT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
REGS1_k127_276843_4	338969.Rfer_3467	2.415e-114	377.0	COG4977@1|root,COG4977@2|Bacteria,1MXAU@1224|Proteobacteria,2WEWY@28216|Betaproteobacteria,4AF1U@80864|Comamonadaceae	28216|Betaproteobacteria	K	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
REGS1_k127_276843_3	580332.Slit_2180	1.958e-135	445.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2VH2B@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
REGS1_k127_2792818_1	580332.Slit_2279	2.26e-171	541.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,44V5T@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_2792818_2	179408.Osc7112_5017	1.253e-105	351.0	COG0633@1|root,COG2114@1|root,COG0633@2|Bacteria,COG2114@2|Bacteria,1G45F@1117|Cyanobacteria,1H867@1150|Oscillatoriales	1117|Cyanobacteria	CT	PFAM adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2,Guanylate_cyc
REGS1_k127_2792818_0	1288494.EBAPG3_17870	1.102e-205	644.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,2VJSV@28216|Betaproteobacteria,372DS@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	camA	-	1.18.1.3	ko:K00529,ko:K18227,ko:K18249	ko00071,ko00360,ko00622,ko00627,ko01120,ko01220,map00071,map00360,map00622,map00627,map01120,map01220	M00539,M00545,M00637	R00823,R00825,R02000,R05247,R06782,R06783	RC00098,RC00192,RC00267	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
REGS1_k127_2792818_3	395494.Galf_2656	1.303e-29	117.0	COG3781@1|root,COG3781@2|Bacteria,1MX91@1224|Proteobacteria,2VHY9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
REGS1_k127_2817389_0	365046.Rta_19330	5.409e-305	954.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4AGK7@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_2817389_10	1249627.D779_2645	6.044e-08	61.0	2EVMX@1|root,33P1X@2|Bacteria,1NK24@1224|Proteobacteria,1SIT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CheW
REGS1_k127_2817389_5	1144319.PMI16_02510	4.329e-33	134.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,472U1@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
REGS1_k127_2817389_8	1298920.KI911353_gene3155	8.028e-22	96.0	COG4430@1|root,COG5646@1|root,COG4430@2|Bacteria,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,24K4J@186801|Clostridia,2217F@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801,OmdA
REGS1_k127_2817389_3	338969.Rfer_0151	2.01e-75	259.0	COG2378@1|root,COG2378@2|Bacteria,1MXS8@1224|Proteobacteria,2VP6N@28216|Betaproteobacteria,4AEAT@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM Helix-turn-helix, type 11 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
REGS1_k127_2817389_1	338969.Rfer_0150	2.495e-157	503.0	COG4335@1|root,COG4335@2|Bacteria,1P0C1@1224|Proteobacteria,2VISN@28216|Betaproteobacteria,4ADJS@80864|Comamonadaceae	28216|Betaproteobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation,HEAT
REGS1_k127_2817389_4	1005048.CFU_2830	2.124e-62	219.0	COG0431@1|root,COG0431@2|Bacteria,1N305@1224|Proteobacteria,2VTD8@28216|Betaproteobacteria,477C1@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_2817389_9	338969.Rfer_0152	1.511e-13	74.0	2EGVV@1|root,30IU2@2|Bacteria,1Q0HK@1224|Proteobacteria,2W5BF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2817389_6	1485544.JQKP01000013_gene1788	1.419e-27	113.0	COG3070@1|root,COG3070@2|Bacteria,1NEFA@1224|Proteobacteria,2VYN2@28216|Betaproteobacteria	28216|Betaproteobacteria	K	TfoX C-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C
REGS1_k127_2817389_2	1536774.H70357_22890	1.398e-89	304.0	COG3214@1|root,COG3214@2|Bacteria,1UYQ5@1239|Firmicutes,4HE15@91061|Bacilli,26U3N@186822|Paenibacillaceae	91061|Bacilli	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
REGS1_k127_2839815_1	580332.Slit_1999	3.508e-109	359.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,44VIY@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_2839815_7	580332.Slit_1998	3.291e-45	167.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria,44VZV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YCII-related domain	yciI	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
REGS1_k127_2839815_2	580332.Slit_1997	1.076e-89	297.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria,44VRS@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Intracellular septation protein A	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
REGS1_k127_2839815_6	580332.Slit_1996	1.404e-73	254.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,44VWV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	SelR
REGS1_k127_2839815_0	580332.Slit_1994	5.494e-286	882.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,44VHZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
REGS1_k127_2839815_4	580332.Slit_1993	5.64e-81	271.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,44VTM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_2839815_5	580332.Slit_1991	5.767e-79	265.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,44VT1@713636|Nitrosomonadales	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
REGS1_k127_2839815_3	580332.Slit_1990	1.774e-83	279.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,44VUE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_2839815_8	580332.Slit_1989	2.437e-12	67.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,44VYG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
REGS1_k127_2930248_4	580332.Slit_0933	1.448e-114	376.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,44WFA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_2930248_0	580332.Slit_0934	0.0	1634.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44VNU@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_2930248_5	580332.Slit_2208	1.236e-102	336.0	COG2230@1|root,COG2230@2|Bacteria,1QXKQ@1224|Proteobacteria,2WHPJ@28216|Betaproteobacteria,44VP5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_2930248_3	1123269.NX02_28525	7.493e-123	409.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,2U7R9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	COG1541 Coenzyme F390 synthetase	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding
REGS1_k127_2930248_9	1287116.X734_27750	8.228e-56	205.0	2CDRQ@1|root,32RYB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_2930248_11	349521.HCH_01678	7.398e-23	104.0	COG3185@1|root,COG3185@2|Bacteria,1QZ9S@1224|Proteobacteria,1S9NN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
REGS1_k127_2930248_1	312153.Pnuc_1096	7.841e-213	682.0	COG0457@1|root,COG0859@1|root,COG3118@1|root,COG0457@2|Bacteria,COG0859@2|Bacteria,COG3118@2|Bacteria,1PEV4@1224|Proteobacteria,2W92U@28216|Betaproteobacteria,1K1Y1@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,TPR_1,TPR_10,TPR_16,TPR_2,TPR_8
REGS1_k127_2930248_2	754477.Q7C_1866	1.875e-169	600.0	COG3210@1|root,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,1RSAX@1236|Gammaproteobacteria,4608F@72273|Thiotrichales	72273|Thiotrichales	U	haemagglutination activity domain	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
REGS1_k127_2930248_6	365044.Pnap_4013	3.688e-92	323.0	COG2831@1|root,COG2831@2|Bacteria,1PRBP@1224|Proteobacteria,2VHDS@28216|Betaproteobacteria,4A9SS@80864|Comamonadaceae	28216|Betaproteobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA,POTRA_2,ShlB
REGS1_k127_2930248_8	946483.Cenrod_0211	3.858e-64	238.0	COG4254@1|root,COG4254@2|Bacteria,1NBPR@1224|Proteobacteria,2VWWI@28216|Betaproteobacteria,4AH9S@80864|Comamonadaceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
REGS1_k127_2930248_7	580332.Slit_2205	3.282e-77	259.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,2VR2G@28216|Betaproteobacteria,44VT6@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thioredoxin	trxC	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
REGS1_k127_2930248_10	580332.Slit_2204	5.646e-39	146.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,44V18@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
REGS1_k127_2942156_5	395494.Galf_1210	1.388e-65	224.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,44W5Y@713636|Nitrosomonadales	28216|Betaproteobacteria	P	K+ potassium transporter	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
REGS1_k127_2942156_2	580332.Slit_2391	2.139e-110	359.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VH0C@28216|Betaproteobacteria,44VIU@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
REGS1_k127_2942156_4	580332.Slit_2392	3.126e-103	340.0	COG2878@1|root,COG2878@2|Bacteria,1MUWU@1224|Proteobacteria,2VN5I@28216|Betaproteobacteria,44VN8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4_21
REGS1_k127_2942156_0	580332.Slit_2393	3.464e-274	851.0	COG4656@1|root,COG4656@2|Bacteria,1PJVF@1224|Proteobacteria,2VM4P@28216|Betaproteobacteria,44VIW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_17,Fer4_8,RnfC_N,SLBB
REGS1_k127_2942156_1	580332.Slit_2394	2.124e-200	627.0	COG4658@1|root,COG4658@2|Bacteria,1MVY6@1224|Proteobacteria,2VJZJ@28216|Betaproteobacteria,44VB4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
REGS1_k127_2942156_3	580332.Slit_2395	3.307e-109	364.0	COG4659@1|root,COG4659@2|Bacteria,1RDEP@1224|Proteobacteria,2VS39@28216|Betaproteobacteria,44VR1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
REGS1_k127_2942156_6	580332.Slit_2396	2.731e-34	132.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,44UYJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
REGS1_k127_2955011_2	580332.Slit_0939	1.996e-164	519.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,44VJF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
REGS1_k127_2955011_1	580332.Slit_2526	1.12e-193	612.0	COG0387@1|root,COG0387@2|Bacteria,1MWD8@1224|Proteobacteria,2VJQM@28216|Betaproteobacteria,44V5W@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM sodium calcium exchanger membrane region	-	-	-	ko:K07300	-	-	-	-	ko00000,ko02000	2.A.19	-	-	Na_Ca_ex
REGS1_k127_2955011_5	580332.Slit_0927	4.411e-99	325.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria,44VST@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_2955011_6	62928.azo0048	1.042e-95	320.0	COG4676@1|root,COG4676@2|Bacteria,1R4HE@1224|Proteobacteria,2VP30@28216|Betaproteobacteria,2KXYF@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized protein conserved in bacteria (DUF2135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2135
REGS1_k127_2955011_7	29581.BW37_03582	6.455e-94	314.0	COG4676@1|root,COG4676@2|Bacteria,1R801@1224|Proteobacteria,2VPGN@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2135)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2135
REGS1_k127_2955011_3	95619.PM1_0206235	1.113e-137	457.0	COG5445@1|root,COG5445@2|Bacteria,1QBHH@1224|Proteobacteria,1S0FA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Stage II sporulation protein	yfaQ	-	-	-	-	-	-	-	-	-	-	-	DUF2300,SpoIID
REGS1_k127_2955011_0	29581.BW37_03584	0.0	1607.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VMEI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM alpha-2-macroglobulin domain protein	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Thiol-ester_cl
REGS1_k127_2955011_11	1440052.EAKF1_ch3752	1.348e-56	204.0	COG3234@1|root,COG3234@2|Bacteria,1R6VA@1224|Proteobacteria,1RXXS@1236|Gammaproteobacteria,3XNZE@561|Escherichia	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1175)	yfaT	-	-	ko:K09934	-	-	-	-	ko00000	-	-	-	DUF1175
REGS1_k127_2955011_4	29581.BW37_03586	5.738e-121	406.0	COG4685@1|root,COG4685@2|Bacteria,1MY31@1224|Proteobacteria,2VNU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2138)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2138
REGS1_k127_2955011_8	580332.Slit_1558	5.137e-79	269.0	arCOG05203@1|root,31A0K@2|Bacteria,1RHZR@1224|Proteobacteria,2VX85@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2955011_9	1121935.AQXX01000142_gene2325	6.254e-72	250.0	28I6Z@1|root,2Z89U@2|Bacteria,1R8YM@1224|Proteobacteria,1S0GG@1236|Gammaproteobacteria,1XNAN@135619|Oceanospirillales	135619|Oceanospirillales	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2955011_10	1122194.AUHU01000003_gene2002	1.439e-67	238.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria,1RSAN@1236|Gammaproteobacteria,4642U@72275|Alteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3020697_2	580332.Slit_2630	2.162e-31	124.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,44VEE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
REGS1_k127_3020697_0	580332.Slit_2631	0.0	1753.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,44VK0@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
REGS1_k127_3020697_1	1485544.JQKP01000001_gene1021	5.87e-65	224.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,44VTD@713636|Nitrosomonadales	28216|Betaproteobacteria	V	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
REGS1_k127_3084995_2	580332.Slit_0323	2.299e-38	145.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3084995_1	1120971.AUCA01000058_gene2773	2.705e-94	318.0	COG0384@1|root,COG0384@2|Bacteria,1UZGV@1239|Firmicutes,4HA56@91061|Bacilli	91061|Bacilli	S	Phenazine biosynthesis-like protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
REGS1_k127_3084995_0	596151.DesfrDRAFT_0706	4.997e-122	413.0	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43D68@68525|delta/epsilon subdivisions,2X8CY@28221|Deltaproteobacteria,2MHGD@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_3084995_3	580332.Slit_2188	0.0002039	47.0	COG0500@1|root,COG2226@2|Bacteria,1PPKI@1224|Proteobacteria	1224|Proteobacteria	Q	Methyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
REGS1_k127_311973_3	580332.Slit_1835	2.437e-95	315.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,44VD6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	2-oxoglutarate dehydrogenase N-terminus	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
REGS1_k127_311973_0	580332.Slit_1836	2.043e-253	785.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,44VKZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
REGS1_k127_311973_5	580332.Slit_1837	4.898e-28	117.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,2VY7W@28216|Betaproteobacteria,44W4H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
REGS1_k127_311973_1	580332.Slit_1838	3.731e-148	471.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,44VM4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
REGS1_k127_311973_4	644282.Deba_2541	3.427e-46	171.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42U5G@68525|delta/epsilon subdivisions,2WQ28@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
REGS1_k127_311973_2	580332.Slit_1839	2.527e-125	402.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,44V9G@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_3128268_4	1163617.SCD_n00720	2.923e-49	182.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,2VH1V@28216|Betaproteobacteria	28216|Betaproteobacteria	K	crp fnr family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
REGS1_k127_3128268_5	713587.THITH_10875	5.451e-25	111.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,1RP04@1236|Gammaproteobacteria,1WW77@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	-	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
REGS1_k127_3128268_2	686340.Metal_3166	6.104e-109	364.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
REGS1_k127_3128268_0	580332.Slit_2313	2.238e-183	575.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,44VKS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
REGS1_k127_3128268_1	1163617.SCD_n02134	3.322e-115	373.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,2VI2Y@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1,3.1.11.6	ko:K03601,ko:K04564	ko03430,ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map03430,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Sod_Fe_C,Sod_Fe_N
REGS1_k127_3128268_3	580332.Slit_2311	5.137e-90	300.0	COG4252@1|root,COG4252@2|Bacteria,1R9GK@1224|Proteobacteria,2VKE8@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM CHASE2 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2
REGS1_k127_3132871_1	580332.Slit_0442	5.462e-201	634.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,44VNP@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
REGS1_k127_3132871_4	1485544.JQKP01000001_gene1186	3.743e-155	496.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,44V7U@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
REGS1_k127_3132871_8	580332.Slit_0440	1.496e-97	319.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,44VQ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_3
REGS1_k127_3132871_11	580332.Slit_0439	5.933e-64	224.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,44VWE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
REGS1_k127_3132871_13	395494.Galf_0278	5.849e-48	178.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,44VXS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
REGS1_k127_3132871_6	580332.Slit_0437	1.197e-136	436.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,44V0H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_3132871_0	580332.Slit_0436	3.28e-245	765.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,44UZ8@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
REGS1_k127_3132871_12	580332.Slit_0435	1.424e-54	192.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,44W0Q@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
REGS1_k127_3132871_10	580332.Slit_0434	1.627e-81	272.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,44VUH@713636|Nitrosomonadales	28216|Betaproteobacteria	GT	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
REGS1_k127_3132871_3	580332.Slit_0433	6.985e-166	525.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,44V87@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
REGS1_k127_3132871_5	580332.Slit_0432	6.012e-137	442.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,44V0U@713636|Nitrosomonadales	28216|Betaproteobacteria	S	P-loop ATPase protein family	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
REGS1_k127_3132871_16	1000565.METUNv1_03287	2.597e-19	93.0	COG5341@1|root,COG5341@2|Bacteria,1N1PN@1224|Proteobacteria,2VUW8@28216|Betaproteobacteria,2KWYI@206389|Rhodocyclales	206389|Rhodocyclales	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
REGS1_k127_3132871_9	580332.Slit_0430	1.485e-88	295.0	COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,2VRM1@28216|Betaproteobacteria,44VVI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
REGS1_k127_3132871_7	580332.Slit_0429	7.389e-119	384.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,44VAK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
REGS1_k127_3132871_14	234267.Acid_3152	2.274e-34	141.0	2C5YZ@1|root,334J2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3132871_2	580332.Slit_0427	7.514e-196	613.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,44VDA@713636|Nitrosomonadales	28216|Betaproteobacteria	L	endonuclease III	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
REGS1_k127_3226174_0	580332.Slit_0126	0.0	1065.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,44V7S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
REGS1_k127_3226174_1	1123257.AUFV01000003_gene987	9.583e-152	499.0	COG0596@1|root,COG2771@1|root,COG0596@2|Bacteria,COG2771@2|Bacteria,1RGAP@1224|Proteobacteria,1S1M7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,GerE
REGS1_k127_322728_7	580332.Slit_2925	7.051e-10	59.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,44VKA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
REGS1_k127_322728_0	580332.Slit_2926	1.277e-265	822.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,44V04@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Nitrogen metabolism transcriptional regulator, NtrC, Fis Family	ntrC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_322728_2	580332.Slit_2927	1.175e-128	419.0	COG3511@1|root,COG3511@2|Bacteria,1RCY1@1224|Proteobacteria,2WEZW@28216|Betaproteobacteria,44WCM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
REGS1_k127_322728_4	1485544.JQKP01000002_gene1595	1.18e-64	221.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,2VSKS@28216|Betaproteobacteria,44VY9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
REGS1_k127_322728_5	1120999.JONM01000004_gene3562	5.248e-35	136.0	COG3668@1|root,COG3668@2|Bacteria,1PSEU@1224|Proteobacteria,2WATI@28216|Betaproteobacteria,2KTQW@206351|Neisseriales	206351|Neisseriales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_322728_6	580332.Slit_2970	4.437e-28	115.0	COG3905@1|root,COG3905@2|Bacteria,1N7SQ@1224|Proteobacteria,2VVRJ@28216|Betaproteobacteria,44WJZ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_322728_3	626418.bglu_2g16070	7.55e-127	414.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VP05@28216|Betaproteobacteria,1K8AN@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_322728_1	580332.Slit_2969	6.844e-144	458.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,44VA7@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
REGS1_k127_3426334_0	580332.Slit_0105	2.056e-280	868.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,44VJY@713636|Nitrosomonadales	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
REGS1_k127_3454309_3	580332.Slit_2081	1.111e-83	282.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2WAJ5@28216|Betaproteobacteria,44VDR@713636|Nitrosomonadales	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
REGS1_k127_3454309_7	395494.Galf_0171	7.453e-47	172.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,44W29@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
REGS1_k127_3454309_6	395494.Galf_0170	6.192e-51	188.0	COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VV1S@28216|Betaproteobacteria,44W1X@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
REGS1_k127_3454309_8	395494.Galf_0169	2.426e-36	143.0	COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria,44W3Z@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
REGS1_k127_3454309_2	395494.Galf_0168	4.514e-88	304.0	COG4966@1|root,COG4966@2|Bacteria,1RDRS@1224|Proteobacteria,2WFYC@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV Pilus-assembly protein W	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilW
REGS1_k127_3454309_4	395494.Galf_0167	1.273e-71	248.0	COG4726@1|root,COG4726@2|Bacteria,1N9CE@1224|Proteobacteria,2VWPP@28216|Betaproteobacteria,44W26@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3454309_0	395494.Galf_0166	0.0	1482.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,44V4V@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
REGS1_k127_3454309_1	580332.Slit_2088	2.171e-172	544.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,44V90@713636|Nitrosomonadales	28216|Betaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
REGS1_k127_3454309_5	1485544.JQKP01000002_gene1383	7.432e-59	208.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,44VXG@713636|Nitrosomonadales	28216|Betaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
REGS1_k127_3454309_9	1156919.QWC_30358	3.132e-16	78.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,3T1IX@506|Alcaligenaceae	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
REGS1_k127_347724_10	1403819.BATR01000075_gene2206	1.234e-25	110.0	2E1H4@1|root,32WVB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_347724_1	580332.Slit_1331	7.302e-276	850.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,44VI7@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
REGS1_k127_347724_3	580332.Slit_1330	9.623e-175	559.0	COG0745@1|root,COG2206@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1RAQS@1224|Proteobacteria,2VQE0@28216|Betaproteobacteria,44WFJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,PAS_4
REGS1_k127_347724_7	580332.Slit_1329	6.995e-82	276.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
REGS1_k127_347724_8	272123.Anacy_5295	5.973e-71	259.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4251@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4251@2|Bacteria,1GQ9E@1117|Cyanobacteria,1HIP0@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,Pkinase
REGS1_k127_347724_5	395494.Galf_1845	1.581e-95	332.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHI5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
REGS1_k127_347724_2	580332.Slit_1327	3.849e-230	751.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,2WHFM@28216|Betaproteobacteria,44WPK@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
REGS1_k127_347724_6	395494.Galf_0103	5.001e-94	318.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,2W9A5@28216|Betaproteobacteria,44WGW@713636|Nitrosomonadales	28216|Betaproteobacteria	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	-
REGS1_k127_347724_0	580332.Slit_1326	2.023e-308	949.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,44V1K@713636|Nitrosomonadales	28216|Betaproteobacteria	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
REGS1_k127_347724_4	580332.Slit_1325	5.143e-101	331.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,44V88@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
REGS1_k127_3504806_7	1123392.AQWL01000007_gene993	2.68e-117	384.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,2VJCC@28216|Betaproteobacteria,1KSWE@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
REGS1_k127_3504806_0	580332.Slit_0953	2.185e-276	852.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,44VN3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
REGS1_k127_3504806_14	580332.Slit_2211	2.19e-26	128.0	COG4254@1|root,COG4254@2|Bacteria,1PGBS@1224|Proteobacteria,2VQEE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
REGS1_k127_3504806_11	580332.Slit_2212	5.563e-77	277.0	COG0457@1|root,COG0457@2|Bacteria,1P464@1224|Proteobacteria,2VMYZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF560)	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
REGS1_k127_3504806_13	580332.Slit_0952	1.213e-64	223.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,2VSDU@28216|Betaproteobacteria,44VUZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
REGS1_k127_3504806_3	580332.Slit_0951	1.113e-133	439.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,2VHF1@28216|Betaproteobacteria,44V75@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
REGS1_k127_3504806_4	580332.Slit_0950	1.487e-131	426.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,44V0C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
REGS1_k127_3504806_8	580332.Slit_0949	1.296e-114	372.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,44W91@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
REGS1_k127_3504806_10	580332.Slit_0948	7.906e-81	274.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,44VXI@713636|Nitrosomonadales	28216|Betaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
REGS1_k127_3504806_1	580332.Slit_0947	4.374e-256	797.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,44VAR@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
REGS1_k127_3504806_6	580332.Slit_0946	1.866e-121	392.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,44VMB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
REGS1_k127_3504806_15	1205908.AKXW01000021_gene980	3.601e-25	119.0	28IW1@1|root,2Z8UB@2|Bacteria,1N1QM@1224|Proteobacteria,1RR0J@1236|Gammaproteobacteria,1XSR0@135623|Vibrionales	135623|Vibrionales	S	F plasmid transfer operon, TraF, protein	-	-	-	-	-	-	-	-	-	-	-	-	TraF_2
REGS1_k127_3504806_9	580332.Slit_0944	1.254e-99	331.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,44VQF@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bacterial dnaA  protein	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
REGS1_k127_3504806_5	395494.Galf_0603	1.885e-130	426.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2VHDW@28216|Betaproteobacteria,44WDZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	AI-2E family transporter	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_3504806_2	580332.Slit_0943	2.487e-217	677.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,44VG1@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
REGS1_k127_3504806_12	580332.Slit_0942	1.649e-76	259.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,44VND@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
REGS1_k127_3517473_9	580332.Slit_0105	1.482e-44	162.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,44VJY@713636|Nitrosomonadales	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
REGS1_k127_3517473_8	1123487.KB892842_gene4222	3.174e-45	171.0	COG2391@1|root,COG2391@2|Bacteria,1MZC0@1224|Proteobacteria,2VT72@28216|Betaproteobacteria,2KXG5@206389|Rhodocyclales	206389|Rhodocyclales	S	transporter component	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3517473_7	1123487.KB892842_gene4221	2.528e-48	177.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2VSDD@28216|Betaproteobacteria,2KX6D@206389|Rhodocyclales	206389|Rhodocyclales	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_3517473_4	395494.Galf_0010	5.215e-100	331.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,44V67@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
REGS1_k127_3517473_1	580332.Slit_0036	1.966e-226	704.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,44V9X@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
REGS1_k127_3517473_3	580332.Slit_0035	3.358e-109	356.0	COG2890@1|root,COG2890@2|Bacteria,1R0WI@1224|Proteobacteria	1224|Proteobacteria	J	TIGRFAM methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	MetW
REGS1_k127_3517473_0	580332.Slit_0034	2.218e-228	711.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,44VM1@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
REGS1_k127_3517473_13	1349767.GJA_2765	8.934e-14	74.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2VIX0@28216|Betaproteobacteria,473DG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF455)	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
REGS1_k127_3517473_10	312153.Pnuc_0687	1.104e-24	106.0	COG4456@1|root,COG4456@2|Bacteria,1N7E4@1224|Proteobacteria,2VW9G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K18829	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
REGS1_k127_3517473_6	1387312.BAUS01000002_gene583	1.974e-58	205.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2VWH6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
REGS1_k127_3517473_2	1163617.SCD_n02366	2.406e-121	396.0	COG2833@1|root,COG2833@2|Bacteria,1MW0V@1224|Proteobacteria,2VIX0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF455
REGS1_k127_3517473_5	580332.Slit_0032	2.189e-95	320.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,2VRSR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Predicted membrane protein (DUF2238)	yjdF	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
REGS1_k127_3517473_12	713587.THITH_03440	1.745e-19	91.0	COG2442@1|root,COG2442@2|Bacteria,1N7GJ@1224|Proteobacteria,1SCUP@1236|Gammaproteobacteria,1WZKZ@135613|Chromatiales	135613|Chromatiales	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
REGS1_k127_352532_2	580332.Slit_2413	2.608e-55	194.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,44V9P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
REGS1_k127_352532_6	1385935.N836_07065	1.91e-08	60.0	COG4828@1|root,COG4828@2|Bacteria,1G7QK@1117|Cyanobacteria,1HCE7@1150|Oscillatoriales	1117|Cyanobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
REGS1_k127_352532_4	395494.Galf_2529	1.669e-26	115.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria,44WKX@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	TusA
REGS1_k127_352532_3	580332.Slit_2415	4.812e-47	171.0	COG0607@1|root,COG0607@2|Bacteria,1QAME@1224|Proteobacteria,2W7JQ@28216|Betaproteobacteria,44VZW@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_352532_1	580332.Slit_2416	2.231e-209	658.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_352532_0	580332.Slit_2417	1.396e-213	672.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,44VK3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M48	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
REGS1_k127_3534584_2	580332.Slit_1254	5.55e-137	440.0	COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,2VN44@28216|Betaproteobacteria,44VEW@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_3534584_3	395494.Galf_2264	1.19e-136	439.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
REGS1_k127_3534584_7	556269.ACDQ01000002_gene979	1.126e-16	83.0	2E6BG@1|root,330Z9@2|Bacteria,1N126@1224|Proteobacteria,2VW8F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3534584_0	580332.Slit_1259	4.952e-268	837.0	COG0665@1|root,COG4121@1|root,COG0665@2|Bacteria,COG4121@2|Bacteria,1MZW5@1224|Proteobacteria,2VHGY@28216|Betaproteobacteria,44WDQ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	S-adenosyl-L-methionine-dependent methyltransferase	mnmC	-	2.1.1.61	ko:K15461	-	-	R00601,R08702	RC00003,RC00053,RC00060,RC01483	ko00000,ko01000,ko03016	-	-	-	DAO,Methyltransf_30
REGS1_k127_3534584_1	580332.Slit_1260	4.304e-159	503.0	COG2518@1|root,COG2518@2|Bacteria,1NMMQ@1224|Proteobacteria,2VH3B@28216|Betaproteobacteria,44VBR@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
REGS1_k127_3534584_5	580332.Slit_1261	4.239e-63	218.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,44VWR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
REGS1_k127_3534584_4	580332.Slit_2040	1.297e-93	311.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,44VSH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Nudix N-terminal	nudC_1	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
REGS1_k127_3534584_6	580332.Slit_2039	2.86e-60	211.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,44V65@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
REGS1_k127_3535747_2	580332.Slit_0141	2.188e-135	437.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,44VIA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
REGS1_k127_3535747_1	395494.Galf_2795	4.117e-175	562.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,44VDN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
REGS1_k127_3535747_0	580332.Slit_0139	2.16e-318	987.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,44VBN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
REGS1_k127_3535747_4	580332.Slit_0138	1.176e-87	292.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,44VW1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
REGS1_k127_3535747_3	580332.Slit_0137	6.791e-130	421.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,44VN9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
REGS1_k127_3541216_1	580332.Slit_0718	4.467e-186	586.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,44WA4@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_3541216_9	269482.Bcep1808_0165	4.396e-11	68.0	2EGYW@1|root,33AR0@2|Bacteria,1NM8U@1224|Proteobacteria,2VZ2G@28216|Betaproteobacteria,1K974@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3541216_6	580332.Slit_0717	2.343e-72	247.0	COG2050@1|root,COG2050@2|Bacteria,1NCGT@1224|Proteobacteria,2VYRW@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
REGS1_k127_3541216_3	580332.Slit_0507	1.516e-115	379.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,44VI1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
REGS1_k127_3541216_0	580332.Slit_0508	0.0	1086.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,44VP2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	RNB	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
REGS1_k127_3541216_7	580332.Slit_0509	3.059e-52	190.0	COG5126@1|root,COG5126@2|Bacteria,1PTFF@1224|Proteobacteria,2WAHF@28216|Betaproteobacteria,44WMJ@713636|Nitrosomonadales	28216|Betaproteobacteria	DTZ	SMART Calcium-binding EF-hand-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
REGS1_k127_3541216_8	580332.Slit_0510	8.755e-27	113.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44W1Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_3541216_2	580332.Slit_0511	5.571e-140	455.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,44VFD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
REGS1_k127_3541216_5	580332.Slit_0512	1.275e-96	317.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,44VRQ@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
REGS1_k127_3541216_4	580332.Slit_0513	1.886e-108	356.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,2VJX1@28216|Betaproteobacteria,44VIP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
REGS1_k127_3544999_2	580332.Slit_1307	3.573e-108	352.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2VJGS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
REGS1_k127_3544999_1	580332.Slit_1308	1.538e-149	483.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria	28216|Betaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	HlyD_3
REGS1_k127_3544999_3	580332.Slit_1309	4.901e-60	210.0	COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria	1224|Proteobacteria	K	Transcription regulator that can specifically activate or repress expression of target genes	slyA	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
REGS1_k127_3544999_0	580332.Slit_1315	0.0	1048.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,44VAI@713636|Nitrosomonadales	28216|Betaproteobacteria	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
REGS1_k127_3566983_2	1163617.SCD_n01887	7.491e-156	494.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase,OmpA
REGS1_k127_3566983_1	1266925.JHVX01000002_gene896	2.519e-164	526.0	COG2200@1|root,COG3279@1|root,COG2200@2|Bacteria,COG3279@2|Bacteria,1N299@1224|Proteobacteria,2VKSH@28216|Betaproteobacteria,372CK@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,Response_reg
REGS1_k127_3566983_0	1288494.EBAPG3_25000	5.129e-217	727.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,374RC@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
REGS1_k127_3566983_3	395494.Galf_1848	1.569e-52	193.0	COG2984@1|root,COG2984@2|Bacteria,1NACH@1224|Proteobacteria,2VSU8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	transport system periplasmic component	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
REGS1_k127_3581570_3	1485544.JQKP01000013_gene1812	6.624e-40	152.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,44VYG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
REGS1_k127_3581570_2	580332.Slit_1988	3.418e-97	323.0	COG3235@1|root,COG3235@2|Bacteria,1RDHR@1224|Proteobacteria,2VRKF@28216|Betaproteobacteria,44VUS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cobalt uptake substrate-specific transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CbiM
REGS1_k127_3581570_1	580332.Slit_1987	5.725e-131	428.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,44V6Z@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM glycine cleavage T protein (aminomethyl transferase)	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
REGS1_k127_3581570_0	395494.Galf_2216	0.0	1142.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,44W8T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
REGS1_k127_3581570_6	1163617.SCD_n00701	4.035e-21	93.0	2ENM6@1|root,33G8J@2|Bacteria,1NI7V@1224|Proteobacteria,2W533@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3602575_0	580332.Slit_1367	4.914e-196	616.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,44VD3@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
REGS1_k127_3602575_2	580332.Slit_1366	2.134e-102	336.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,44V9Z@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
REGS1_k127_3602575_3	580332.Slit_1365	4.642e-57	201.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,44VVS@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
REGS1_k127_3602575_1	580332.Slit_1364	3.711e-159	506.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,44UYT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
REGS1_k127_3602575_4	580332.Slit_1363	6.156e-25	107.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,44W2Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Trm112p-like protein	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
REGS1_k127_3602575_5	580332.Slit_1362	1.166e-22	100.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,44VH9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
REGS1_k127_3632229_1	580332.Slit_0265	2.989e-64	232.0	2AFYG@1|root,31628@2|Bacteria,1PWQT@1224|Proteobacteria,2WC9D@28216|Betaproteobacteria,44VMT@713636|Nitrosomonadales	580332.Slit_0265|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3632229_3	395961.Cyan7425_4757	2.177e-17	85.0	2EA6P@1|root,334BF@2|Bacteria,1G9KH@1117|Cyanobacteria,3KKHT@43988|Cyanothece	1117|Cyanobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
REGS1_k127_3632229_2	1173027.Mic7113_4762	3.703e-30	122.0	COG3668@1|root,COG3668@2|Bacteria,1G7UC@1117|Cyanobacteria,1HDRH@1150|Oscillatoriales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_3632229_0	580332.Slit_0445	0.0	1823.0	COG1643@1|root,COG2852@1|root,COG1643@2|Bacteria,COG2852@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,44VDV@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
REGS1_k127_3635575_4	580332.Slit_0365	4.122e-19	87.0	COG0764@1|root,COG0764@2|Bacteria,1N8Q8@1224|Proteobacteria,2VVQ1@28216|Betaproteobacteria,44WKG@713636|Nitrosomonadales	28216|Betaproteobacteria	I	FabA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	FabA
REGS1_k127_3635575_2	580332.Slit_0366	1.242e-148	477.0	COG4261@1|root,COG4261@2|Bacteria,1MVXJ@1224|Proteobacteria,2VHP0@28216|Betaproteobacteria,44W9Y@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Lip_A_acyltrans
REGS1_k127_3635575_3	1485544.JQKP01000005_gene400	7.91e-80	271.0	COG2834@1|root,COG2834@2|Bacteria,1RHYN@1224|Proteobacteria,2VSXY@28216|Betaproteobacteria,44WC9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	LolA
REGS1_k127_3635575_0	580332.Slit_0368	0.0	1071.0	COG4258@1|root,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,2VHXY@28216|Betaproteobacteria,44WBH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
REGS1_k127_3635575_1	1485544.JQKP01000005_gene402	1.876e-234	729.0	COG0475@1|root,COG0475@2|Bacteria,1PK6U@1224|Proteobacteria,2WAEY@28216|Betaproteobacteria,44WJS@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
REGS1_k127_3690015_18	580332.Slit_1629	1.639e-14	74.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,44VHQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
REGS1_k127_3690015_7	395494.Galf_1597	1.146e-153	490.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,44VHP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DNA polymerase alpha chain like domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
REGS1_k127_3690015_16	580332.Slit_1631	1.327e-42	159.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,44VZ5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
REGS1_k127_3690015_13	580332.Slit_1632	4.04e-64	223.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,44VUY@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	ratA	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
REGS1_k127_3690015_11	580332.Slit_1633	3.408e-82	274.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,44VSM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
REGS1_k127_3690015_9	580332.Slit_1634	2.469e-89	297.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VKRT@28216|Betaproteobacteria,44VRJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
REGS1_k127_3690015_14	580332.Slit_1636	1.383e-63	224.0	COG5615@1|root,COG5615@2|Bacteria,1N3BK@1224|Proteobacteria,2VQHM@28216|Betaproteobacteria,44WI1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Copper resistance protein D	-	-	-	-	-	-	-	-	-	-	-	-	CopD
REGS1_k127_3690015_8	580332.Slit_1637	3.615e-98	325.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,44VRD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
REGS1_k127_3690015_3	580332.Slit_1638	1.394e-207	649.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,44VEA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
REGS1_k127_3690015_5	580332.Slit_1639	2.804e-156	495.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria,44V5C@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
REGS1_k127_3690015_10	580332.Slit_1640	6.349e-88	294.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,44VTF@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
REGS1_k127_3690015_4	580332.Slit_1641	2.567e-185	583.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,44V3V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
REGS1_k127_3690015_12	580332.Slit_1642	4.847e-65	227.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,44VX8@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
REGS1_k127_3690015_0	580332.Slit_1643	0.0	1166.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,44V63@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
REGS1_k127_3690015_1	580332.Slit_1644	1.498e-233	728.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,44V27@713636|Nitrosomonadales	28216|Betaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
REGS1_k127_3690015_2	580332.Slit_1645	1.373e-214	672.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,44V71@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
REGS1_k127_3690015_15	1266925.JHVX01000003_gene470	3.483e-48	183.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,3729J@32003|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
REGS1_k127_3690015_6	580332.Slit_1647	1.562e-154	489.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,44V2T@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
REGS1_k127_3690015_19	265072.Mfla_1527	6.57e-11	63.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,2KM1Y@206350|Nitrosomonadales	206350|Nitrosomonadales	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
REGS1_k127_3695811_6	748449.Halha_0394	9.999e-40	151.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3WBCA@53433|Halanaerobiales	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_3695811_3	580332.Slit_2116	1.258e-103	340.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria,44VEB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
REGS1_k127_3695811_2	580332.Slit_2118	5.371e-144	461.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,44V8K@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
REGS1_k127_3695811_5	580332.Slit_2119	6.756e-81	275.0	COG0619@1|root,COG0619@2|Bacteria,1N7EI@1224|Proteobacteria,2VWJT@28216|Betaproteobacteria,44VYV@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	-	-	-	-	-	-	-	-	-	CbiQ
REGS1_k127_3695811_0	580332.Slit_2120	1.64e-242	779.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,44VR7@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
REGS1_k127_3695811_1	580332.Slit_2121	5.529e-224	696.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,44W4D@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_3695811_4	580332.Slit_2122	2.116e-97	319.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,44VCP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_3708131_1	1125863.JAFN01000001_gene796	2.325e-88	304.0	COG2067@1|root,COG2067@2|Bacteria,1NUFX@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3708131_2	653733.Selin_1274	1.784e-61	222.0	COG4784@1|root,COG4784@2|Bacteria	2|Bacteria	S	Peptidase m48 ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_3708131_4	653733.Selin_1275	9.053e-17	87.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	2.7.11.1	ko:K02450,ko:K12132	-	M00331	-	-	ko00000,ko00002,ko01000,ko01001,ko02044	9.B.42	-	-	CHAP,DUF1302,Glucosaminidase,Pkinase,SH3_3,SH3_5,SLH
REGS1_k127_3708131_0	653733.Selin_1276	4.646e-128	432.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria	2|Bacteria	T	Chase2 domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_3708131_3	395494.Galf_1165	2.392e-35	135.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VNAZ@28216|Betaproteobacteria,44W6M@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
REGS1_k127_3724729_3	580332.Slit_1325	3.697e-73	248.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,44V88@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
REGS1_k127_3724729_2	1123261.AXDW01000001_gene1393	6.951e-76	267.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,1S4XC@1236|Gammaproteobacteria,1X548@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_3724729_0	266264.Rmet_2800	4.991e-98	330.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,2VMS5@28216|Betaproteobacteria,1K3TH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
REGS1_k127_3724729_1	580332.Slit_1324	6.96e-81	273.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,44WF4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
REGS1_k127_3724729_5	395494.Galf_0407	5.296e-53	190.0	COG1858@1|root,COG1858@2|Bacteria,1QVT1@1224|Proteobacteria,2WGTP@28216|Betaproteobacteria,44WIA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
REGS1_k127_3724729_4	580332.Slit_1322	2.329e-55	201.0	2FG6B@1|root,3482S@2|Bacteria,1P2BQ@1224|Proteobacteria,2W87X@28216|Betaproteobacteria,44WHR@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3761087_5	580332.Slit_2142	1.598e-58	206.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,44VAB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
REGS1_k127_3761087_1	580332.Slit_2143	1.485e-223	697.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,44VJQ@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	lplT	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_3761087_6	864051.BurJ1DRAFT_0044	1.349e-26	109.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,1KMJF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
REGS1_k127_3761087_4	395494.Galf_2002	1.237e-58	205.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	XK27_07670	-	-	-	-	-	-	-	-	-	-	-	OsmC
REGS1_k127_3761087_0	580332.Slit_2351	1.913e-227	706.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,44VKN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
REGS1_k127_3761087_2	580332.Slit_2352	3.01e-111	361.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,44VSB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
REGS1_k127_3761087_3	580332.Slit_2353	1.783e-107	351.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,44VSG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
REGS1_k127_3790849_19	580332.Slit_1367	1.185e-35	138.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,44VD3@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
REGS1_k127_3790849_5	580332.Slit_1375	9.22e-169	532.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,2VKEP@28216|Betaproteobacteria,44VD4@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	arnD	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_3790849_9	717772.THIAE_09070	1.151e-115	393.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1RPPS@1236|Gammaproteobacteria,46100@72273|Thiotrichales	72273|Thiotrichales	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_3790849_16	1163617.SCD_n01748	7.371e-51	190.0	COG0671@1|root,COG0671@2|Bacteria,1NAJ7@1224|Proteobacteria,2VX11@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_3790849_14	580332.Slit_1378	6.276e-62	217.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2VTC8@28216|Betaproteobacteria,44WK9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
REGS1_k127_3790849_12	580332.Slit_1379	2.671e-89	297.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,2VRGS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
REGS1_k127_3790849_22	269797.Mbar_A2123	2.84e-22	102.0	COG1403@1|root,arCOG03898@2157|Archaea	2157|Archaea	V	COG1403 Restriction endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
REGS1_k127_3790849_6	580332.Slit_1380	2.179e-161	515.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,44VBB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
REGS1_k127_3790849_3	580332.Slit_1381	2.877e-226	706.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VJXD@28216|Betaproteobacteria,44V3C@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
REGS1_k127_3790849_21	933262.AXAM01000175_gene2922	7.023e-30	130.0	2DP71@1|root,330U0@2|Bacteria,1R5A0@1224|Proteobacteria,42X0W@68525|delta/epsilon subdivisions,2WSIB@28221|Deltaproteobacteria,2MMBG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
REGS1_k127_3790849_18	857087.Metme_4106	1.056e-36	140.0	COG1669@1|root,COG1669@2|Bacteria,1N17I@1224|Proteobacteria,1SDT6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
REGS1_k127_3790849_0	580332.Slit_1383	9.874e-311	968.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,44V5V@713636|Nitrosomonadales	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
REGS1_k127_3790849_8	640081.Dsui_2875	2.564e-119	398.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,2VHU4@28216|Betaproteobacteria,2KXX0@206389|Rhodocyclales	206389|Rhodocyclales	M	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_3790849_7	395494.Galf_1760	3.338e-151	488.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,44V0M@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
REGS1_k127_3790849_11	640081.Dsui_2877	7.466e-112	366.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria,2KXSK@206389|Rhodocyclales	206389|Rhodocyclales	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_3790849_4	395494.Galf_1762	4.384e-190	604.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,44VN6@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_3790849_17	395494.Galf_0299	2.906e-39	151.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_3790849_13	580332.Slit_1388	4.081e-82	277.0	COG0810@1|root,COG0810@2|Bacteria,1MZPX@1224|Proteobacteria,2WA18@28216|Betaproteobacteria,44W3V@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
REGS1_k127_3790849_10	580332.Slit_1389	1.534e-114	371.0	COG0811@1|root,COG0811@2|Bacteria,1NMPB@1224|Proteobacteria,2VJ4U@28216|Betaproteobacteria,44VYJ@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
REGS1_k127_3790849_15	580332.Slit_1390	1.611e-60	212.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,2VU7B@28216|Betaproteobacteria,44W2H@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559,ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.1,1.A.30.2.2	-	-	ExbD
REGS1_k127_3790849_1	1485544.JQKP01000001_gene1315	1.076e-283	877.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,44VIH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N,PNTB_4TM
REGS1_k127_3790849_2	395494.Galf_1320	9.821e-272	839.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,44VMQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
REGS1_k127_3790849_20	1112274.KI911560_gene150	6.374e-34	133.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria,2KMQM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
REGS1_k127_3806429_0	580332.Slit_0364	4.98e-190	601.0	COG0318@1|root,COG0318@2|Bacteria,1MXPB@1224|Proteobacteria,2VJ3A@28216|Betaproteobacteria,44W5T@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
REGS1_k127_3806429_2	580332.Slit_0363	3.58e-90	301.0	COG4648@1|root,COG4648@2|Bacteria,1RII0@1224|Proteobacteria,2VSMC@28216|Betaproteobacteria,44WCB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3806429_1	580332.Slit_0362	1.432e-133	434.0	COG0500@1|root,COG2226@2|Bacteria,1MVXG@1224|Proteobacteria,2VM9F@28216|Betaproteobacteria,44W6K@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
REGS1_k127_3842706_1	580332.Slit_2699	3.374e-171	540.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,44VBF@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
REGS1_k127_3842706_0	395494.Galf_0294	3.794e-199	628.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria,44V5P@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Domain of unknown function DUF21	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
REGS1_k127_3842706_3	395494.Galf_2495	2.205e-101	344.0	COG2829@1|root,COG2829@2|Bacteria,1PC8I@1224|Proteobacteria,2VKGK@28216|Betaproteobacteria,44WAC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Phospholipase A1	pldA	-	3.1.1.32,3.1.1.4	ko:K01058	ko00564,ko00565,ko00590,ko00591,ko00592,ko01100,ko01110,map00564,map00565,map00590,map00591,map00592,map01100,map01110	-	R01315,R01316,R01317,R02053,R02054,R04034,R07064,R07379,R07387,R07859,R07860	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko01000	-	-	-	PLA1
REGS1_k127_3842706_2	580332.Slit_2697	1.686e-159	505.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,44V26@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
REGS1_k127_3887900_2	395494.Galf_2935	5.432e-51	182.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,44V6D@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
REGS1_k127_3887900_0	580332.Slit_2982	1.962e-162	513.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,2VJBW@28216|Betaproteobacteria,44V00@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
REGS1_k127_3887900_1	580332.Slit_2981	1.047e-66	228.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,44V86@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
REGS1_k127_3899909_2	580332.Slit_0129	9.611e-84	280.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,44UYR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_3899909_1	580332.Slit_0128	7.972e-96	317.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,44VUB@713636|Nitrosomonadales	28216|Betaproteobacteria	O	DSBA-like thioredoxin domain	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
REGS1_k127_3899909_3	580332.Slit_0127	1.088e-43	167.0	COG3087@1|root,COG3087@2|Bacteria,1N4QG@1224|Proteobacteria,2VUXF@28216|Betaproteobacteria,44VZ6@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
REGS1_k127_3899909_0	580332.Slit_0126	0.0	1023.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,44V7S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
REGS1_k127_3915834_7	580332.Slit_2353	7.599e-13	68.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,44VSG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
REGS1_k127_3915834_2	580332.Slit_2354	6.207e-181	568.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,44VJC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
REGS1_k127_3915834_3	580332.Slit_2355	1.395e-155	501.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,44V4C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
REGS1_k127_3915834_5	580332.Slit_2356	1.631e-63	222.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
REGS1_k127_3915834_1	580332.Slit_2357	9.635e-220	697.0	COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,44VNS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
REGS1_k127_3915834_0	1485544.JQKP01000002_gene1421	0.0	1589.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VKKR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
REGS1_k127_3915834_4	1485544.JQKP01000002_gene1420	2.984e-119	394.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VI8Z@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
REGS1_k127_3915834_6	1485544.JQKP01000002_gene1419	3.552e-40	153.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VHFP@28216|Betaproteobacteria,44WDN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_3919331_6	1123368.AUIS01000009_gene2509	1.814e-72	251.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RQ3P@1236|Gammaproteobacteria,2NCP7@225057|Acidithiobacillales	225057|Acidithiobacillales	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
REGS1_k127_3919331_1	580332.Slit_1807	7.078e-306	946.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria,44VA8@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
REGS1_k127_3919331_2	580332.Slit_1808	1.483e-254	788.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,44V10@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
REGS1_k127_3919331_3	580332.Slit_1809	2.597e-239	747.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,44V0E@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Starch synthase catalytic domain	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
REGS1_k127_3919331_4	517418.Ctha_1613	1.046e-228	720.0	COG0166@1|root,COG0166@2|Bacteria,1FDEJ@1090|Chlorobi	1090|Chlorobi	F	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
REGS1_k127_3919331_0	580332.Slit_1811	0.0	1358.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
REGS1_k127_3919331_8	1120963.KB894491_gene1107	4.107e-09	57.0	2DE24@1|root,2ZK69@2|Bacteria,1P9N5@1224|Proteobacteria,1SU0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3919331_5	580332.Slit_1833	8.471e-177	558.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,44WDD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_3919331_7	118168.MC7420_5350	3.925e-15	78.0	COG3668@1|root,COG3668@2|Bacteria,1G8P7@1117|Cyanobacteria,1HC8S@1150|Oscillatoriales	1117|Cyanobacteria	S	Addiction module toxin, RelE StbE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_4002527_0	580332.Slit_1214	5.029e-58	202.0	COG3668@1|root,COG3668@2|Bacteria,1PJWP@1224|Proteobacteria,2W88C@28216|Betaproteobacteria,44WJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_4002527_1	395494.Galf_2610	4.278e-35	135.0	COG2161@1|root,COG2161@2|Bacteria,1NEWX@1224|Proteobacteria,2WCQS@28216|Betaproteobacteria,44WIC@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_4002527_2	1485544.JQKP01000020_gene75	1.124e-26	109.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,2VR7G@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
REGS1_k127_4050499_2	1485544.JQKP01000017_gene644	4.927e-79	265.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,44VDJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
REGS1_k127_4050499_1	768671.ThimaDRAFT_1500	9.044e-101	333.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,1RQYI@1236|Gammaproteobacteria,1WYF0@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
REGS1_k127_4050499_3	1454004.AW11_01193	0.0002404	51.0	COG1864@1|root,COG2931@1|root,COG3179@1|root,COG3209@1|root,COG3391@1|root,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3179@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,1RC1P@1224|Proteobacteria,2VUZC@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19
REGS1_k127_4050499_0	1038869.AXAN01000063_gene4617	1.18e-167	531.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,2W5BV@28216|Betaproteobacteria,1K5NQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_4110944_4	1163617.SCD_n02025	3.735e-38	149.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria	28216|Betaproteobacteria	CP	NADH Ubiquinone plastoquinone (Complex I)	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
REGS1_k127_4110944_3	580332.Slit_2562	2.346e-108	354.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria,44W5S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
REGS1_k127_4110944_2	580332.Slit_2563	1.854e-158	506.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria,44W66@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH dehydrogenase	hyfD	-	-	-	-	-	-	-	-	-	-	-	NADHdh
REGS1_k127_4110944_1	580332.Slit_2564	0.0	1076.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,2VMAN@28216|Betaproteobacteria,44WCY@713636|Nitrosomonadales	28216|Betaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	hyfB	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
REGS1_k127_4110944_0	580332.Slit_2567	0.0	2101.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,44VF6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
REGS1_k127_4110944_5	543728.Vapar_3939	1.255e-26	110.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,2VJHC@28216|Betaproteobacteria,4ADQU@80864|Comamonadaceae	28216|Betaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	wbiG	-	1.1.1.219,5.1.3.2	ko:K00091,ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_421343_0	580332.Slit_0807	9.882e-177	556.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VIRD@28216|Betaproteobacteria,44WCU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	HMGL-like	nifV	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
REGS1_k127_421343_1	1485544.JQKP01000001_gene984	8.776e-141	449.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VMGF@28216|Betaproteobacteria,44WCG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	nifP	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
REGS1_k127_421343_2	580332.Slit_0809	1.436e-84	282.0	COG0457@1|root,COG0457@2|Bacteria,1R714@1224|Proteobacteria,2VRZB@28216|Betaproteobacteria,44WD3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_421343_4	580332.Slit_0810	1.872e-53	189.0	2E67S@1|root,330W8@2|Bacteria,1NA3E@1224|Proteobacteria,2VX71@28216|Betaproteobacteria,44WGB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nitrogen fixation protein NifW	nifW	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
REGS1_k127_421343_3	580332.Slit_0811	2.518e-83	278.0	COG0760@1|root,COG0760@2|Bacteria,1QUCX@1224|Proteobacteria,2WGPH@28216|Betaproteobacteria,44WFU@713636|Nitrosomonadales	28216|Betaproteobacteria	O	NifZ domain	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
REGS1_k127_4282785_7	1485544.JQKP01000002_gene1627	8.272e-172	547.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,44UZV@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
REGS1_k127_4282785_3	580332.Slit_2721	4.841e-243	756.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,44V6N@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
REGS1_k127_4282785_4	580332.Slit_2722	2.864e-221	691.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,44V5Q@713636|Nitrosomonadales	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
REGS1_k127_4282785_9	395494.Galf_0330	4.294e-167	537.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,44VA0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_4282785_2	580332.Slit_2724	1.115e-259	808.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,44VE4@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_4282785_0	580332.Slit_2725	1.468e-292	906.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,44VFB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
REGS1_k127_4282785_16	580332.Slit_2726	8.356e-34	133.0	COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria,44W2Z@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
REGS1_k127_4282785_8	580332.Slit_2727	9.846e-169	533.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,44VNN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
REGS1_k127_4282785_14	580332.Slit_2728	1.571e-83	278.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,44VXJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
REGS1_k127_4282785_5	640081.Dsui_0668	5.639e-200	654.0	COG5373@1|root,COG5373@2|Bacteria,1N08V@1224|Proteobacteria,2VKJT@28216|Betaproteobacteria,2KVH0@206389|Rhodocyclales	206389|Rhodocyclales	C	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
REGS1_k127_4282785_15	1123228.AUIH01000007_gene2520	1.378e-49	185.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S739@1236|Gammaproteobacteria,1XKC3@135619|Oceanospirillales	135619|Oceanospirillales	D	COG1192 ATPases involved in chromosome partitioning	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
REGS1_k127_4282785_12	580332.Slit_0260	3.077e-133	427.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2WEFP@28216|Betaproteobacteria,44V6W@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LytTr DNA-binding domain	algR	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
REGS1_k127_4282785_11	580332.Slit_0259	4.929e-135	440.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,44VQA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine kinase	algZ	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
REGS1_k127_4282785_1	580332.Slit_0258	1.313e-271	841.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,44VK4@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
REGS1_k127_4282785_13	1163617.SCD_n00466	2.469e-86	295.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
REGS1_k127_4282785_6	572477.Alvin_0977	5.79e-176	567.0	COG2199@1|root,COG2199@2|Bacteria,1R3XS@1224|Proteobacteria,1SKQU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
REGS1_k127_4282785_10	580332.Slit_0256	1.929e-159	503.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,44VAN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_4519404_8	1129794.C427_4423	2.812e-31	135.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,DUF285,MucBP,SdrD_B
REGS1_k127_4519404_4	323848.Nmul_A0517	1.086e-46	175.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,2VKFN@28216|Betaproteobacteria,374M7@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Domain of unknown function (DUF4124)	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
REGS1_k127_4519404_3	365044.Pnap_4542	9.919e-54	196.0	2C6BU@1|root,32S87@2|Bacteria,1NIFE@1224|Proteobacteria,2VRGB@28216|Betaproteobacteria,4AGT5@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4519404_7	1552758.NC00_13465	1.123e-32	128.0	COG3905@1|root,COG3905@2|Bacteria,1NB4C@1224|Proteobacteria,1SEYQ@1236|Gammaproteobacteria,1X8YZ@135614|Xanthomonadales	135614|Xanthomonadales	K	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
REGS1_k127_4519404_6	62928.azo3077	9.372e-37	143.0	COG3668@1|root,COG3668@2|Bacteria,1N9C2@1224|Proteobacteria,2VWK0@28216|Betaproteobacteria,2KXN9@206389|Rhodocyclales	206389|Rhodocyclales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_4519404_2	316067.Geob_3253	4.601e-80	282.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_4519404_0	580332.Slit_2782	0.0	1386.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,44V8A@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
REGS1_k127_4519404_5	1123399.AQVE01000006_gene3563	2.474e-37	147.0	2DNKW@1|root,32Y18@2|Bacteria,1ND1M@1224|Proteobacteria,1SQBD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4519404_1	580332.Slit_2781	0.0	1221.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,44V5N@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
REGS1_k127_4581857_3	1123368.AUIS01000016_gene2549	1.508e-22	104.0	2E3Q5@1|root,32YN4@2|Bacteria,1NA23@1224|Proteobacteria,1SJGF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilN
REGS1_k127_4581857_6	1132855.KB913035_gene747	2.101e-08	55.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,2VKD6@28216|Betaproteobacteria,2KNE8@206350|Nitrosomonadales	206350|Nitrosomonadales	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
REGS1_k127_4581857_4	1408444.JHYC01000008_gene1427	5.283e-16	78.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4581857_0	580332.Slit_1539	9.55e-284	874.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,44V1T@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_4581857_2	1116472.MGMO_3c00020	2.795e-48	179.0	COG0642@1|root,COG2198@1|root,COG0642@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RX35@1236|Gammaproteobacteria,1XG3G@135618|Methylococcales	135618|Methylococcales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_4581857_5	318161.Sden_1918	1.106e-09	61.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1TCTI@1236|Gammaproteobacteria,2QDJ6@267890|Shewanellaceae	1236|Gammaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
REGS1_k127_4581857_1	1121918.ARWE01000001_gene2215	1.555e-126	411.0	COG2199@1|root,COG3706@2|Bacteria,1R5N6@1224|Proteobacteria	1224|Proteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_4631529_5	580332.Slit_2741	1.553e-08	57.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,44VCY@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
REGS1_k127_4631529_1	580332.Slit_2740	4.372e-141	452.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,44V5D@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome C assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_4631529_4	580332.Slit_2739	2.597e-44	165.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,44W0A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
REGS1_k127_4631529_2	580332.Slit_2738	8.855e-95	312.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,44VVG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
REGS1_k127_4631529_0	580332.Slit_2737	7.769e-156	493.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,44V1B@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
REGS1_k127_4631529_3	580332.Slit_2736	6.165e-64	221.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,44VSX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
REGS1_k127_4632352_0	1485544.JQKP01000001_gene922	2.298e-259	806.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,44VGZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
REGS1_k127_4632352_1	279714.FuraDRAFT_1304	1.362e-50	200.0	COG0288@1|root,COG0288@2|Bacteria,1RKKR@1224|Proteobacteria,2VTB7@28216|Betaproteobacteria,2KSCZ@206351|Neisseriales	206351|Neisseriales	P	Carbonic anhydrase	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
REGS1_k127_4637079_3	580332.Slit_0942	9.223e-41	151.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,44VND@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
REGS1_k127_4637079_2	1485544.JQKP01000003_gene154	1.427e-53	196.0	COG3147@1|root,COG3147@2|Bacteria,1R129@1224|Proteobacteria,2WHYD@28216|Betaproteobacteria,44VVT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
REGS1_k127_4637079_1	580332.Slit_0940	4.429e-71	253.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria,44VTY@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
REGS1_k127_4637079_0	580332.Slit_0939	9.672e-92	307.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,44VJF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
REGS1_k127_4640299_0	580332.Slit_0060	0.0	1130.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,44V3A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation region	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
REGS1_k127_4640299_2	580332.Slit_0061	2.247e-67	231.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_4640299_1	580332.Slit_0062	1.395e-289	892.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,44V3K@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
REGS1_k127_4646482_11	1229204.AMYY01000002_gene2550	1.036e-06	51.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2TUAH@28211|Alphaproteobacteria,4BRPB@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	MA20_25110	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
REGS1_k127_4646482_3	296591.Bpro_3095	1.516e-101	338.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria,4AAJH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
REGS1_k127_4646482_6	580332.Slit_2306	1.354e-24	108.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
REGS1_k127_4646482_4	903818.KI912268_gene2380	2.854e-68	244.0	COG2885@1|root,COG2885@2|Bacteria,3Y5IQ@57723|Acidobacteria	57723|Acidobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF937,OmpA
REGS1_k127_4646482_2	580332.Slit_1251	6.941e-103	337.0	COG0778@1|root,COG0778@2|Bacteria,1R9VX@1224|Proteobacteria,2VQ1J@28216|Betaproteobacteria,44VF8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM nitroreductase	-	-	-	ko:K09019	ko00240,ko01100,map00240,map01100	-	R09289	RC00087	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
REGS1_k127_4646482_5	580332.Slit_1238	1.975e-44	164.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,2VX81@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4646482_1	1163617.SCD_n01367	1.091e-229	719.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,2VHR4@28216|Betaproteobacteria	28216|Betaproteobacteria	E	aminoacyl-histidine dipeptidase	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_4646482_10	1541065.JRFE01000007_gene5148	1.335e-14	84.0	COG0484@1|root,COG0484@2|Bacteria,1G0V5@1117|Cyanobacteria,3VIV3@52604|Pleurocapsales	1117|Cyanobacteria	O	DnaJ-class molecular chaperone with C-terminal Zn finger domain	dnaJ3	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
REGS1_k127_4646482_8	159087.Daro_3953	3.27e-18	95.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,NERD
REGS1_k127_4646482_0	314345.SPV1_01352	0.0	1061.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_4664447_7	1380394.JADL01000016_gene405	7.655e-26	110.0	COG3569@1|root,COG3569@2|Bacteria,1MVJ9@1224|Proteobacteria,2TUAH@28211|Alphaproteobacteria,2JR0N@204441|Rhodospirillales	204441|Rhodospirillales	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_I
REGS1_k127_4664447_0	580332.Slit_2509	2.095e-254	791.0	28HIY@1|root,2Z7U8@2|Bacteria,1MY3K@1224|Proteobacteria,2VKE4@28216|Betaproteobacteria,44V51@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4664447_4	580332.Slit_1242	2.011e-48	176.0	COG0664@1|root,COG0664@2|Bacteria,1N6WV@1224|Proteobacteria,2VWSV@28216|Betaproteobacteria,44WIM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_4664447_6	580332.Slit_1244	1.948e-36	139.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,44W19@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
REGS1_k127_4664447_3	580332.Slit_1245	1.422e-51	186.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,44W18@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
REGS1_k127_4664447_5	1173028.ANKO01000114_gene6148	1.44e-43	183.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,1H7BV@1150|Oscillatoriales	1117|Cyanobacteria	S	COG0666 FOG Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
REGS1_k127_4664447_2	580332.Slit_1246	2.14e-103	338.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,44VRH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
REGS1_k127_4664447_1	395494.Galf_2603	4.296e-181	572.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,2WGS2@28216|Betaproteobacteria,44VBH@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_4664845_5	261292.Nit79A3_2192	1.221e-31	129.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VJKH@28216|Betaproteobacteria,37393@32003|Nitrosomonadales	28216|Betaproteobacteria	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
REGS1_k127_4664845_3	395494.Galf_1378	1.127e-73	257.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2VK9Q@28216|Betaproteobacteria,44WPJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,PAS_9,SnoaL_3
REGS1_k127_4664845_2	697282.Mettu_4312	4.918e-182	576.0	COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,1RY7N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	GfdT protein	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
REGS1_k127_4664845_4	395494.Galf_1579	1.436e-42	160.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,2VUFZ@28216|Betaproteobacteria,44WI7@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
REGS1_k127_4664845_0	395494.Galf_0059	0.0	1001.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,44V9S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_21,Pyr_redox_2,Pyr_redox_3
REGS1_k127_4664845_1	395494.Galf_0060	2.304e-192	605.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Thiamine pyrophosphate	porB	-	1.2.1.58,1.2.7.1	ko:K00170,ko:K18356	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_11,Fer4_6,TPP_enzyme_C
REGS1_k127_4664845_6	395494.Galf_0061	1.61e-17	81.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2W99Y@28216|Betaproteobacteria,44WKY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
REGS1_k127_4677767_0	580332.Slit_2413	0.0	1641.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,44V9P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
REGS1_k127_4692706_3	580332.Slit_0672	3.567e-39	153.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,44V9I@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
REGS1_k127_4692706_0	580332.Slit_0671	1.298e-193	609.0	COG3034@1|root,COG3034@2|Bacteria,1N2B6@1224|Proteobacteria,2VJXB@28216|Betaproteobacteria,44V3Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_4692706_2	580332.Slit_0670	2.526e-94	312.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,44VQD@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
REGS1_k127_4692706_1	580332.Slit_0669	4.714e-110	360.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,44VBW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
REGS1_k127_4692706_4	1232410.KI421416_gene2662	6.779e-10	64.0	2EB1N@1|root,3352G@2|Bacteria,1NDEY@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4713343_1	580332.Slit_2461	2.393e-155	496.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,2VN24@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
REGS1_k127_4713343_0	580332.Slit_2462	0.0	1036.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,2VI53@28216|Betaproteobacteria,44VCU@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	yjcC	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
REGS1_k127_4713343_2	580332.Slit_2464	2.353e-127	413.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,44W16@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_4713343_3	580332.Slit_2465	8.442e-22	98.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,44WCP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
REGS1_k127_4713838_6	580332.Slit_0538	0.0001663	48.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,44W47@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
REGS1_k127_4713838_1	580332.Slit_0539	7.993e-258	805.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,2VQUC@28216|Betaproteobacteria,44WD9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
REGS1_k127_4713838_5	580332.Slit_0978	1.397e-110	362.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,44VCG@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
REGS1_k127_4713838_2	580332.Slit_0979	5.423e-144	467.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,44V32@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
REGS1_k127_4713838_0	580332.Slit_0982	0.0	1030.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,44VCR@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_4713838_4	580332.Slit_0983	1.229e-119	391.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,44V9A@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
REGS1_k127_4713838_3	1395571.TMS3_0122845	1.92e-124	405.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite permeases	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
REGS1_k127_4737105_5	580332.Slit_2719	5.367e-06	48.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,44V43@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
REGS1_k127_4737105_0	580332.Slit_2718	4.886e-263	815.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,44VEH@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Mur ligase family, catalytic domain	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_4737105_3	580332.Slit_2717	1.178e-149	484.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2W9FB@28216|Betaproteobacteria,44WEF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	-	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
REGS1_k127_4737105_1	580332.Slit_2716	7.229e-170	537.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
REGS1_k127_4737105_4	580332.Slit_2715	3.783e-105	346.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,44VRY@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
REGS1_k127_4737105_2	580332.Slit_2714	1.827e-156	495.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,44UZY@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
REGS1_k127_4746253_1	580332.Slit_1728	2.077e-182	574.0	COG0446@1|root,COG0446@2|Bacteria,1QTP3@1224|Proteobacteria,2W9DC@28216|Betaproteobacteria,44WBG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_4746253_2	580332.Slit_2618	2.018e-147	473.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,44VMF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
REGS1_k127_4746253_4	404589.Anae109_3936	2.426e-24	117.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	CarboxypepD_reg,DUF11,LTD,SdrD_B
REGS1_k127_4746253_3	580332.Slit_2619	1.564e-44	164.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,44VY1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	bigR	-	-	-	-	-	-	-	-	-	-	-	HTH_5
REGS1_k127_4746253_0	580332.Slit_2620	1.319e-296	914.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,44V6E@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
REGS1_k127_4746253_5	580332.Slit_2621	1.078e-17	89.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,44VHE@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_4747464_2	580332.Slit_1579	4.31e-116	375.0	COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1QU8R@1224|Proteobacteria,2WHYG@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
REGS1_k127_4747464_1	580332.Slit_1754	3.167e-121	391.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,44UYP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_4747464_0	580332.Slit_1753	3.763e-173	546.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,44V82@713636|Nitrosomonadales	28216|Betaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
REGS1_k127_4747464_3	580332.Slit_1752	7.531e-08	53.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
REGS1_k127_4757977_5	580332.Slit_0736	2.257e-24	102.0	COG0637@1|root,COG0637@2|Bacteria,1QTWD@1224|Proteobacteria,2VNTW@28216|Betaproteobacteria,44UZ1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
REGS1_k127_4757977_2	580332.Slit_0737	3.95e-107	349.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,44WBD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
REGS1_k127_4757977_4	1116375.VEJY3_09640	1.625e-36	144.0	2BSER@1|root,32MGR@2|Bacteria,1RKCI@1224|Proteobacteria,1SIR9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4757977_0	580332.Slit_0739	2.053e-306	942.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,44V3P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
REGS1_k127_4757977_3	580332.Slit_0741	3.866e-95	316.0	COG0748@1|root,COG0748@2|Bacteria,1RFVC@1224|Proteobacteria,2VS07@28216|Betaproteobacteria,44VUT@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07226	-	-	-	-	ko00000	-	-	-	DUF2470,Putative_PNPOx,Pyrid_oxidase_2
REGS1_k127_4757977_1	580332.Slit_0742	3.208e-134	435.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,44VKC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
REGS1_k127_4779993_10	580332.Slit_0632	3.315e-30	120.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,44W2X@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_4779993_7	580332.Slit_0631	1.126e-61	215.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,44VY0@713636|Nitrosomonadales	28216|Betaproteobacteria	FG	HIT domain	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
REGS1_k127_4779993_8	580332.Slit_0630	2.604e-52	185.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,44W06@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
REGS1_k127_4779993_6	395494.Galf_0438	4.371e-71	243.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,44VV6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
REGS1_k127_4779993_3	580332.Slit_0628	1.747e-146	471.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,44VIE@713636|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
REGS1_k127_4779993_2	580332.Slit_0627	8.998e-154	486.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,44UZI@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
REGS1_k127_4779993_4	580332.Slit_0626	2.678e-119	387.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,44V1Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
REGS1_k127_4779993_5	580332.Slit_0625	2.57e-115	372.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,44VGH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
REGS1_k127_4779993_1	580332.Slit_0624	3.307e-187	590.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,44V69@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_4779993_9	580332.Slit_0977	1.049e-48	176.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,44VD1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
REGS1_k127_4779993_0	580332.Slit_0977	8.419e-217	676.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,44VD1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
REGS1_k127_4779993_11	395494.Galf_2461	2.098e-22	97.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,44VVC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	NUDIX domain	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
REGS1_k127_4805406_26	580332.Slit_1345	1.528e-08	55.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,44V2A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
REGS1_k127_4805406_11	580332.Slit_1344	3.022e-79	265.0	COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,2VTB0@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Putative thioesterase (yiiD_Cterm)	-	-	-	-	-	-	-	-	-	-	-	-	YiiD_C
REGS1_k127_4805406_13	580332.Slit_1342	2.61e-67	230.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,44WG5@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
REGS1_k127_4805406_14	580332.Slit_0389	2.697e-65	226.0	COG1656@1|root,COG1656@2|Bacteria	2|Bacteria	F	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
REGS1_k127_4805406_3	580332.Slit_1339	9.92e-153	487.0	COG0697@1|root,COG0697@2|Bacteria,1MYHQ@1224|Proteobacteria,2VJMU@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	eamA1	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_4805406_12	580332.Slit_1015	2.609e-69	237.0	COG2010@1|root,COG2010@2|Bacteria,1N1Z3@1224|Proteobacteria,2VU18@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
REGS1_k127_4805406_16	338969.Rfer_0745	3.458e-55	198.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,4AES2@80864|Comamonadaceae	28216|Betaproteobacteria	C	Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
REGS1_k127_4805406_8	1123401.JHYQ01000013_gene691	1.728e-102	337.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,1RQQ3@1236|Gammaproteobacteria,460MZ@72273|Thiotrichales	72273|Thiotrichales	T	PFAM Response regulator receiver domain	-	-	-	ko:K02483,ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_4805406_2	580332.Slit_1012	3.663e-209	657.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2VJBG@28216|Betaproteobacteria,44W7J@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	qseC	-	2.7.13.3	ko:K07645	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
REGS1_k127_4805406_22	395493.BegalDRAFT_2965	4.482e-26	113.0	2EVMX@1|root,33P1X@2|Bacteria,1NK24@1224|Proteobacteria,1SIT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CheW
REGS1_k127_4805406_0	765913.ThidrDRAFT_0025	8.762e-236	769.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_4805406_4	765913.ThidrDRAFT_0026	1.876e-140	457.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal
REGS1_k127_4805406_23	1196322.A370_04823	1.531e-23	107.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,24EYC@186801|Clostridia,36GXX@31979|Clostridiaceae	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
REGS1_k127_4805406_20	765913.ThidrDRAFT_0027	2.222e-37	150.0	COG0835@1|root,COG0835@2|Bacteria,1NF0B@1224|Proteobacteria,1SD1Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	CheW-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
REGS1_k127_4805406_18	765913.ThidrDRAFT_0028	1.147e-53	190.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_4805406_19	395493.BegalDRAFT_2974	6.062e-40	159.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S364@1236|Gammaproteobacteria,463EC@72273|Thiotrichales	72273|Thiotrichales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_4805406_7	1385517.N800_11095	1.648e-103	355.0	COG0633@1|root,COG1018@1|root,COG2346@1|root,COG0633@2|Bacteria,COG1018@2|Bacteria,COG2346@2|Bacteria,1REP4@1224|Proteobacteria,1T2XC@1236|Gammaproteobacteria,1XDHE@135614|Xanthomonadales	135614|Xanthomonadales	C	Bacterial-like globin	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin,FAD_binding_6,Fer2,NAD_binding_1
REGS1_k127_4805406_21	365044.Pnap_0367	4.053e-28	118.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
REGS1_k127_4805406_15	365044.Pnap_0368	1.168e-59	209.0	COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae	28216|Betaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4805406_9	1123504.JQKD01000117_gene390	8.082e-100	343.0	COG1120@1|root,COG2453@1|root,COG1120@2|Bacteria,COG2453@2|Bacteria,1P0GN@1224|Proteobacteria,2VNDH@28216|Betaproteobacteria,4AC63@80864|Comamonadaceae	28216|Betaproteobacteria	HPT	PFAM Dual specificity protein phosphatase	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	ABC_tran,DSPc
REGS1_k127_4805406_17	637389.Acaty_c2228	1.026e-54	197.0	COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,1S271@1236|Gammaproteobacteria,2NC84@225057|Acidithiobacillales	225057|Acidithiobacillales	S	small GTP-binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
REGS1_k127_4805406_25	1123368.AUIS01000022_gene1045	1.268e-10	70.0	2DBSQ@1|root,2ZATE@2|Bacteria,1N58C@1224|Proteobacteria,1SAPH@1236|Gammaproteobacteria,2NE6B@225057|Acidithiobacillales	225057|Acidithiobacillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4805406_1	395494.Galf_2528	6.174e-228	726.0	COG2202@1|root,COG5001@1|root,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WCD@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Phosphonate-bd
REGS1_k127_4805406_10	323848.Nmul_A0728	1.84e-83	283.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRK9@28216|Betaproteobacteria,372UB@32003|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM Signal transduction response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_4805406_5	395494.Galf_2729	1.052e-118	404.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VJV5@28216|Betaproteobacteria,44VNA@713636|Nitrosomonadales	1224|Proteobacteria	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA_3,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_4805406_6	62928.azo0702	4.733e-104	350.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,2VIXN@28216|Betaproteobacteria,2KV6G@206389|Rhodocyclales	206389|Rhodocyclales	V	Inner membrane protein CreD	-	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
REGS1_k127_4819410_1	395494.Galf_2691	1.554e-114	375.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,44V5F@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	NAD(P)H-binding	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
REGS1_k127_4819410_0	580332.Slit_0273	5.49e-184	579.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,44V1J@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain protein	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
REGS1_k127_4850782_5	580332.Slit_0881	1.132e-81	273.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,2VIK4@28216|Betaproteobacteria	28216|Betaproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
REGS1_k127_4850782_1	580332.Slit_0882	6.467e-305	937.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,2VHMG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Nitrogenase molybdenum-iron protein alpha chain	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
REGS1_k127_4850782_0	580332.Slit_0883	0.0	1001.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,2VIUM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF3364,Oxidored_nitro
REGS1_k127_4850782_7	580332.Slit_0884	1.703e-33	131.0	COG5554@1|root,COG5554@2|Bacteria	2|Bacteria	Q	nitrogen fixation	nifT	-	-	ko:K02593	-	-	-	-	ko00000	-	-	-	NifT
REGS1_k127_4850782_9	580332.Slit_0885	8.925e-32	124.0	COG1145@1|root,COG1145@2|Bacteria,1N859@1224|Proteobacteria,2VXWM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_4850782_2	580332.Slit_0886	1.35e-119	387.0	COG1433@1|root,COG1433@2|Bacteria,1PW6J@1224|Proteobacteria,2WFJ3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DIMCO_N,Nitro_FeMo-Co
REGS1_k127_4850782_6	580332.Slit_0887	2.283e-39	148.0	2E4UR@1|root,32ZP4@2|Bacteria,1N83W@1224|Proteobacteria,2VYMU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4850782_8	435908.IDSA_10145	1.123e-32	128.0	COG1942@1|root,COG1942@2|Bacteria,1N6WW@1224|Proteobacteria,1SC97@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
REGS1_k127_4850782_3	580332.Slit_0897	1.997e-111	366.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,44W87@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
REGS1_k127_4850782_4	580332.Slit_0898	7.188e-109	355.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,44WE5@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
REGS1_k127_4877465_0	580332.Slit_1063	7.745e-162	513.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,44VBG@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_4877465_1	580332.Slit_2800	6.993e-83	284.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_4877465_2	1485544.JQKP01000004_gene504	2.116e-38	143.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,2VI4J@28216|Betaproteobacteria,44V97@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
REGS1_k127_4898899_10	267608.RSc0500	1.33e-181	572.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,1K2TQ@119060|Burkholderiaceae	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
REGS1_k127_4898899_2	596153.Alide_4626	1.308e-297	926.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2VGZB@28216|Betaproteobacteria,4ACRT@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM DNA methylase N-4 N-6	mod	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
REGS1_k127_4898899_3	596153.Alide_4625	5.331e-295	930.0	COG1061@1|root,COG1061@2|Bacteria,1R4TB@1224|Proteobacteria	1224|Proteobacteria	KL	PFAM Type III restriction enzyme, res subunit	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
REGS1_k127_4898899_8	1286631.X805_28020	2.975e-207	655.0	COG2865@1|root,COG2865@2|Bacteria,1R4MD@1224|Proteobacteria,2WFIY@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
REGS1_k127_4898899_22	580332.Slit_0516	4.089e-70	238.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,44VXM@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
REGS1_k127_4898899_15	580332.Slit_0517	5.466e-119	385.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,44VN7@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
REGS1_k127_4898899_23	580332.Slit_0518	6.544e-61	213.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria,44VVP@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
REGS1_k127_4898899_24	580332.Slit_0519	3.89e-59	214.0	COG0810@1|root,COG0810@2|Bacteria,1MZ9F@1224|Proteobacteria,2VKUS@28216|Betaproteobacteria	28216|Betaproteobacteria	M	TIGRFAM TonB family protein	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
REGS1_k127_4898899_9	580332.Slit_0520	3.645e-198	624.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,44V5U@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
REGS1_k127_4898899_26	580332.Slit_0521	3.696e-44	167.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,44W03@713636|Nitrosomonadales	28216|Betaproteobacteria	M	OmpA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
REGS1_k127_4898899_20	580332.Slit_0522	7.062e-85	288.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,44VUU@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
REGS1_k127_4898899_19	580332.Slit_0523	9.653e-112	363.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,44VIV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
REGS1_k127_4898899_13	580332.Slit_0524	8.593e-124	401.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,44V5Y@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
REGS1_k127_4898899_6	580332.Slit_0525	1.537e-231	722.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PPH1@1224|Proteobacteria,2W9GU@28216|Betaproteobacteria,44WKA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
REGS1_k127_4898899_14	580332.Slit_0870	1.548e-120	393.0	2DYMX@1|root,34AD8@2|Bacteria,1R128@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4898899_4	580332.Slit_1447	1.908e-241	760.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2WHYC@28216|Betaproteobacteria,44WNC@713636|Nitrosomonadales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
REGS1_k127_4898899_16	580332.Slit_0868	7.29e-119	391.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Cytochrome_C7,Paired_CXXCH_1
REGS1_k127_4898899_5	580332.Slit_0867	8.006e-237	752.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4898899_7	580332.Slit_0526	1.571e-214	671.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,44UZH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
REGS1_k127_4898899_11	580332.Slit_0527	8.602e-177	556.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,44V0Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
REGS1_k127_4898899_17	580332.Slit_0528	4.154e-118	383.0	COG0861@1|root,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,44VMY@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
REGS1_k127_4898899_25	580332.Slit_0529	5.627e-49	179.0	COG0589@1|root,COG0589@2|Bacteria,1N8EJ@1224|Proteobacteria,2VUAF@28216|Betaproteobacteria,44VW3@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_4898899_0	580332.Slit_0530	0.0	1347.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
REGS1_k127_4898899_12	580332.Slit_0531	1.562e-137	441.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,44W64@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART protein phosphatase 2C domain protein	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
REGS1_k127_4898899_18	580332.Slit_0532	3.678e-113	370.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,44WCZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
REGS1_k127_4898899_1	580332.Slit_0533	0.0	1157.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_4898899_21	580332.Slit_0535	1.949e-71	245.0	COG0607@1|root,COG0664@1|root,COG0607@2|Bacteria,COG0664@2|Bacteria,1R9Q1@1224|Proteobacteria,2VQGZ@28216|Betaproteobacteria	28216|Betaproteobacteria	PT	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,cNMP_binding
REGS1_k127_4906701_1	395494.Galf_2378	0.0	1122.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,44VP7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
REGS1_k127_4906701_4	1485544.JQKP01000004_gene471	6.413e-122	391.0	COG0717@1|root,COG0717@2|Bacteria,1MV2J@1224|Proteobacteria,2VIJ0@28216|Betaproteobacteria,44UYM@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	dUTPase
REGS1_k127_4906701_10	580332.Slit_2542	4.206e-26	109.0	2E8PT@1|root,3330W@2|Bacteria,1N796@1224|Proteobacteria,2VVUA@28216|Betaproteobacteria,44W2D@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4906701_0	580332.Slit_2541	0.0	1460.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,44VED@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Orn Lys Arg decarboxylase major region	adi	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
REGS1_k127_4906701_6	1157708.KB907455_gene3417	1.028e-85	297.0	COG0778@1|root,COG0778@2|Bacteria,1NTK9@1224|Proteobacteria,2VYQ2@28216|Betaproteobacteria,4AGFC@80864|Comamonadaceae	28216|Betaproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_4906701_8	1005999.GLGR_2723	2.799e-60	216.0	COG1309@1|root,COG1309@2|Bacteria,1N11B@1224|Proteobacteria,1S8PU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_4906701_11	1441930.Z042_14465	8.588e-25	111.0	2C5CR@1|root,2ZKH4@2|Bacteria,1P75Y@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
REGS1_k127_4906701_9	580332.Slit_2540	3.349e-55	198.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,44WID@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SMART RNA-binding S4 domain protein	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
REGS1_k127_4906701_3	580332.Slit_2157	3.02e-215	685.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,44WD0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
REGS1_k127_4906701_7	580332.Slit_2539	4.193e-79	268.0	COG0526@1|root,COG0526@2|Bacteria,1RHPC@1224|Proteobacteria,2VTSB@28216|Betaproteobacteria,44WEN@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin,Thioredoxin
REGS1_k127_4906701_2	580332.Slit_2807	1.739e-247	801.0	COG2461@1|root,COG5001@1|root,COG2461@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WBI@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,SBP_bac_3
REGS1_k127_4906701_5	580332.Slit_2532	2.298e-106	347.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,44V28@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
REGS1_k127_4951231_5	580332.Slit_2054	3.116e-60	209.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,44V6M@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
REGS1_k127_4951231_9	580332.Slit_2053	4.38e-37	144.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,2VVT0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Competence protein	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
REGS1_k127_4951231_3	316055.RPE_3624	5.401e-178	561.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2TS33@28211|Alphaproteobacteria,3JQMM@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_4951231_4	215803.DB30_6281	1.048e-90	316.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria,2YZ03@29|Myxococcales	28221|Deltaproteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,REJ
REGS1_k127_4951231_2	580332.Slit_1172	8.194e-179	561.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,44VI4@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_4951231_6	1163617.SCD_n02550	7.697e-50	192.0	COG4313@1|root,COG4313@2|Bacteria,1R5Z9@1224|Proteobacteria,2VKTG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
REGS1_k127_4951231_0	580332.Slit_1178	3.123e-206	648.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,44V74@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
REGS1_k127_4951231_7	1122236.KB905141_gene1012	1.604e-41	162.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,2KMRX@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
REGS1_k127_4951231_1	580332.Slit_1180	7.237e-205	645.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,2VI7V@28216|Betaproteobacteria,44VK1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
REGS1_k127_4951231_8	580332.Slit_2773	8.136e-39	145.0	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria,44WNR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4968545_3	395494.Galf_0608	1.514e-98	324.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,44VGQ@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
REGS1_k127_4968545_4	580332.Slit_2230	1.278e-83	279.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,44VPY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
REGS1_k127_4968545_2	580332.Slit_2229	1.002e-101	338.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,44VJ8@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_4968545_6	580332.Slit_2228	8.051e-67	232.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,44W02@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789,ko:K14742	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
REGS1_k127_4968545_1	580332.Slit_2227	4.724e-111	364.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,44VSC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_4968545_0	580332.Slit_2226	0.0	1358.0	COG2199@1|root,COG2202@1|root,COG5000@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG5000@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHI5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
REGS1_k127_4968545_5	580332.Slit_2224	2.259e-83	278.0	COG0720@1|root,COG0720@2|Bacteria,1RETG@1224|Proteobacteria,2VRBN@28216|Betaproteobacteria,44VRF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
REGS1_k127_4980283_1	395494.Galf_2272	1.871e-169	533.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,44VG4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
REGS1_k127_4980283_5	580332.Slit_0704	6.391e-29	119.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,44W3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
REGS1_k127_4980283_3	580332.Slit_0705	3.104e-143	459.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,44V0J@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_4980283_0	580332.Slit_0706	0.0	1035.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,44VC0@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
REGS1_k127_4980283_2	580332.Slit_0707	2.291e-154	489.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,44V3J@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Type I GTP cyclohydrolase folE2	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
REGS1_k127_4980283_4	580332.Slit_0709	1.701e-100	331.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria,44V94@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
REGS1_k127_4990689_4	395494.Galf_2846	3.029e-141	452.0	COG0451@1|root,COG0451@2|Bacteria,1R6NZ@1224|Proteobacteria	1224|Proteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_4990689_8	1286093.C266_19520	5.343e-95	329.0	COG2244@1|root,COG2244@2|Bacteria,1NCWY@1224|Proteobacteria,2W2YJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4990689_5	1286093.C266_19525	1.94e-126	419.0	COG4641@1|root,COG4641@2|Bacteria,1PF0D@1224|Proteobacteria,2W50C@28216|Betaproteobacteria,1KEW6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
REGS1_k127_4990689_9	563040.Saut_1496	1.509e-62	229.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_4990689_7	1286093.C266_19530	3.006e-108	363.0	2A3UF@1|root,30SCE@2|Bacteria,1R12C@1224|Proteobacteria,2VRQV@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10
REGS1_k127_4990689_6	1286093.C266_19455	8.164e-120	396.0	COG0438@1|root,COG0438@2|Bacteria,1Q04V@1224|Proteobacteria,2W93R@28216|Betaproteobacteria,1KF58@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
REGS1_k127_4990689_1	395494.Galf_2835	1.85e-217	680.0	COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,2VGZN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	glycosyl transferase group 1	-	-	-	ko:K03208	-	-	-	-	ko00000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
REGS1_k127_4990689_3	395494.Galf_2834	1.048e-148	475.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VKA8@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD2	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
REGS1_k127_4990689_2	1268068.PG5_59750	9.769e-167	529.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,1RNQ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	Polysaccharide biosynthesis protein	fnlA	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
REGS1_k127_4990689_0	395494.Galf_2832	1.752e-222	691.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2VJ5C@28216|Betaproteobacteria,44WNS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB1	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
REGS1_k127_4997984_2	1173028.ANKO01000014_gene1061	7.537e-26	115.0	COG4122@1|root,COG4122@2|Bacteria,1G5B0@1117|Cyanobacteria,1HB99@1150|Oscillatoriales	1117|Cyanobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24,TPR_2
REGS1_k127_4997984_0	1366050.N234_07665	6.567e-265	826.0	COG5421@1|root,COG5421@2|Bacteria,1R3NX@1224|Proteobacteria,2VNNI@28216|Betaproteobacteria,1K3QF@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
REGS1_k127_4997984_1	398578.Daci_4800	3.261e-161	514.0	COG1178@1|root,COG1178@2|Bacteria,1R0MN@1224|Proteobacteria,2VK7P@28216|Betaproteobacteria,4AD6E@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
REGS1_k127_5024205_3	580332.Slit_1757	2.473e-33	128.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,44VCM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_5024205_1	580332.Slit_1252	2.703e-187	595.0	COG0477@1|root,COG2814@2|Bacteria,1MU9G@1224|Proteobacteria,2VK6G@28216|Betaproteobacteria,44VCQ@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K19577	-	-	-	-	ko00000,ko02000	2.A.1.2.65	-	-	MFS_1,Sugar_tr
REGS1_k127_5024205_0	580332.Slit_1755	1.639e-189	597.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,2VJ71@28216|Betaproteobacteria,44VBJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	FtsJ-like methyltransferase	rlmM	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
REGS1_k127_5024205_2	1121035.AUCH01000001_gene1772	2.045e-55	201.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2VR9D@28216|Betaproteobacteria,2M021@206389|Rhodocyclales	206389|Rhodocyclales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
REGS1_k127_5059097_1	1134474.O59_000611	1.232e-87	292.0	COG5380@1|root,COG5380@2|Bacteria,1QG74@1224|Proteobacteria	1224|Proteobacteria	O	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
REGS1_k127_5059097_0	580332.Slit_0799	1.425e-242	755.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,44V0W@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	yajR	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
REGS1_k127_5059097_2	580332.Slit_0800	4.942e-87	288.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,44VVD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
REGS1_k127_5059097_3	365046.Rta_14960	2.204e-57	209.0	28HC9@1|root,2Z7P5@2|Bacteria,1R4BH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5065232_8	1238450.VIBNISOn1_1070054	9.024e-45	180.0	2BWG8@1|root,2Z8GJ@2|Bacteria,1RA2S@1224|Proteobacteria,1SMCN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5065232_1	1123399.AQVE01000001_gene753	2.535e-291	908.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,1RN0R@1236|Gammaproteobacteria,463PR@72273|Thiotrichales	72273|Thiotrichales	S	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
REGS1_k127_5065232_7	395494.Galf_2630	3.625e-53	188.0	COG3162@1|root,COG3162@2|Bacteria,1N9T2@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
REGS1_k127_5065232_5	395494.Galf_2631	1.951e-100	332.0	COG0847@1|root,COG0847@2|Bacteria,1RCPS@1224|Proteobacteria,2WEVE@28216|Betaproteobacteria,44WB3@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Exonuclease RNase T and DNA polymerase III	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
REGS1_k127_5065232_0	395494.Galf_2632	1.8e-322	996.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria,44WEE@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
REGS1_k127_5065232_6	580332.Slit_0149	2.097e-61	218.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,44WH5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
REGS1_k127_5065232_2	580332.Slit_0148	4.843e-151	480.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,44V70@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
REGS1_k127_5065232_4	580332.Slit_0147	1.965e-122	393.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,44VRV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
REGS1_k127_5065232_3	580332.Slit_0146	1.396e-148	478.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,44VAD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_5103333_2	395494.Galf_1923	1.949e-179	563.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,2VH92@28216|Betaproteobacteria,44VUJ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TOBE-like domain	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
REGS1_k127_5103333_6	745277.GRAQ_01392	1.02e-99	335.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,1RN7T@1236|Gammaproteobacteria,3FENZ@34037|Rahnella	1236|Gammaproteobacteria	K	Transcriptional regulator	cbl	GO:0006792,GO:0008150,GO:0045883,GO:0048518,GO:0050789,GO:0065007	-	ko:K13634,ko:K13635	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
REGS1_k127_5103333_8	1120999.JONM01000021_gene131	7.431e-40	149.0	COG5470@1|root,COG5470@2|Bacteria,1N7JA@1224|Proteobacteria,2VUU6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
REGS1_k127_5103333_10	1003200.AXXA_01425	1.587e-07	55.0	2EJJ9@1|root,33DA7@2|Bacteria,1NJCG@1224|Proteobacteria,2VXZJ@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5103333_4	580332.Slit_2362	3.32e-129	417.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,44VE9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
REGS1_k127_5103333_1	580332.Slit_2361	3.046e-195	617.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,2VMDE@28216|Betaproteobacteria,44VJT@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
REGS1_k127_5103333_7	580332.Slit_2360	7.198e-92	312.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,2VRRA@28216|Betaproteobacteria,44VS9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
REGS1_k127_5103333_5	580332.Slit_2359	3.184e-106	349.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VJ2B@28216|Betaproteobacteria,44V3I@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
REGS1_k127_5103333_0	1485544.JQKP01000004_gene528	4.079e-211	663.0	COG3659@1|root,COG3659@2|Bacteria,1Q8C7@1224|Proteobacteria,2VJFC@28216|Betaproteobacteria,44W6W@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Carbohydrate-selective porin, OprB family	oprB	-	-	-	-	-	-	-	-	-	-	-	OprB
REGS1_k127_5103333_3	1485544.JQKP01000002_gene1419	1.756e-146	475.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VHFP@28216|Betaproteobacteria,44WDN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_5125370_0	580332.Slit_1279	0.0	1112.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,2VHM5@28216|Betaproteobacteria,44V33@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
REGS1_k127_5125370_1	580332.Slit_1278	1.864e-218	683.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VI4Q@28216|Betaproteobacteria,44VH5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S1 and S6 chymotrypsin Hap	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_5143758_1	580332.Slit_1305	5.516e-87	291.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,44VIM@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
REGS1_k127_5143758_0	1163617.SCD_n00429	3.007e-265	848.0	COG3300@1|root,COG5001@1|root,COG3300@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS_9,dCache_2
REGS1_k127_5143758_2	395494.Galf_0405	6.226e-70	241.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2VQQ7@28216|Betaproteobacteria,44WFY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_5188957_7	580332.Slit_2460	8.251e-87	291.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
REGS1_k127_5188957_0	580332.Slit_2459	1.048e-258	806.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
REGS1_k127_5188957_2	580332.Slit_2458	4.936e-205	647.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
REGS1_k127_5188957_6	580332.Slit_2457	1.883e-88	293.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,44VQJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
REGS1_k127_5188957_8	580332.Slit_2456	1.912e-71	242.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,44VSY@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
REGS1_k127_5188957_3	580332.Slit_2455	4.478e-200	625.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,44V0R@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_5188957_5	580332.Slit_2454	8.415e-97	323.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria,44WF0@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5188957_10	580332.Slit_2453	4.631e-57	203.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,44WIP@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_5188957_9	580332.Slit_2452	6.488e-67	228.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,44VT4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
REGS1_k127_5188957_4	580332.Slit_2451	3.398e-183	585.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria,44V2W@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
REGS1_k127_5188957_1	580332.Slit_2450	1.826e-207	653.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,44V44@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_5242969_5	1127673.GLIP_1186	3.894e-66	245.0	COG3014@1|root,COG3014@2|Bacteria,1RA9U@1224|Proteobacteria	1224|Proteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5242969_6	1089552.KI911559_gene1855	6.801e-60	213.0	COG3417@1|root,COG3417@2|Bacteria,1RAWS@1224|Proteobacteria,2U5DC@28211|Alphaproteobacteria,2JWIR@204441|Rhodospirillales	204441|Rhodospirillales	M	Peptidoglycan-synthase activator LpoB	-	-	-	-	-	-	-	-	-	-	-	-	LpoB
REGS1_k127_5242969_2	580332.Slit_0659	2.615e-91	305.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,2VUA6@28216|Betaproteobacteria,44WFX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
REGS1_k127_5242969_7	748247.AZKH_4320	2.809e-54	195.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,2KW78@206389|Rhodocyclales	206389|Rhodocyclales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
REGS1_k127_5242969_1	580332.Slit_0657	1.531e-150	481.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,2VI0Q@28216|Betaproteobacteria,44VFP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
REGS1_k127_5242969_4	580332.Slit_0656	3.145e-68	235.0	COG0781@1|root,COG0781@2|Bacteria,1RHFZ@1224|Proteobacteria,2VSI6@28216|Betaproteobacteria,44VWD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
REGS1_k127_5242969_3	580332.Slit_0655	9.133e-69	235.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,2VQGE@28216|Betaproteobacteria,44VUK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
REGS1_k127_5242969_0	1485544.JQKP01000013_gene1853	4.777e-178	564.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,2VH6S@28216|Betaproteobacteria,44VKD@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribB	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
REGS1_k127_5242969_8	595537.Varpa_1317	1.928e-42	179.0	COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria,2VT4V@28216|Betaproteobacteria,4AFU0@80864|Comamonadaceae	28216|Betaproteobacteria	O	Ergosterol biosynthesis ERG4/ERG24 family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_5242969_9	580332.Slit_0653	6.51e-11	62.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,44V83@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
REGS1_k127_5251109_0	580332.Slit_1886	0.0	1060.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,2VHVA@28216|Betaproteobacteria,44VDY@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
REGS1_k127_5251109_2	580332.Slit_1885	3.268e-172	541.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,44VM7@713636|Nitrosomonadales	28216|Betaproteobacteria	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
REGS1_k127_5251109_1	580332.Slit_1884	2.631e-248	769.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,44VKW@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
REGS1_k127_5251109_4	1485544.JQKP01000003_gene263	4.913e-30	124.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,44W01@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
REGS1_k127_5251109_3	580332.Slit_1882	3.935e-52	185.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria,44V29@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_5258622_2	1485544.JQKP01000001_gene1144	2.483e-21	94.0	COG5587@1|root,COG5587@2|Bacteria,1R8B4@1224|Proteobacteria,2WAP5@28216|Betaproteobacteria,44WER@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
REGS1_k127_5258622_0	395494.Galf_1124	4.182e-195	621.0	COG2200@1|root,COG3829@1|root,COG2200@2|Bacteria,COG3829@2|Bacteria,1NTHT@1224|Proteobacteria,2W1FA@28216|Betaproteobacteria,44WAB@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	TIGRFAM PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PAS_4
REGS1_k127_5258622_1	395494.Galf_2656	9.681e-156	495.0	COG3781@1|root,COG3781@2|Bacteria,1MX91@1224|Proteobacteria,2VHY9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
REGS1_k127_5261056_3	292415.Tbd_1597	1.266e-15	85.0	COG5581@1|root,COG5581@2|Bacteria,1MX00@1224|Proteobacteria,2VQEK@28216|Betaproteobacteria,1KRTQ@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Flagellar regulator YcgR	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR
REGS1_k127_5261056_2	395494.Galf_1298	1.151e-40	153.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	dgkA	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
REGS1_k127_5261056_1	580332.Slit_2862	3.986e-90	299.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,2VQ18@28216|Betaproteobacteria,44W9Q@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
REGS1_k127_5261056_0	580332.Slit_2861	0.0	1091.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,44V7J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
REGS1_k127_532202_2	1162668.LFE_1385	2.643e-41	154.0	COG0633@1|root,COG0633@2|Bacteria	2|Bacteria	C	Ferredoxin	-	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
REGS1_k127_532202_1	595536.ADVE02000001_gene2934	3.179e-96	322.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,2U1GU@28211|Alphaproteobacteria,36Z6Y@31993|Methylocystaceae	28211|Alphaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
REGS1_k127_532202_0	395494.Galf_1924	1.938e-105	344.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,44WE7@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LysR substrate binding domain	cbl	-	-	ko:K13634,ko:K13635	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
REGS1_k127_5330079_0	580332.Slit_2833	0.0	1236.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,44V1E@713636|Nitrosomonadales	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
REGS1_k127_5330079_3	580332.Slit_2834	2.034e-143	456.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,44VF9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Possible lysine decarboxylase	yvdD_2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
REGS1_k127_5330079_6	580332.Slit_2835	1.881e-38	146.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,44VZF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
REGS1_k127_5330079_2	580332.Slit_2836	4.954e-168	531.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,44V2D@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
REGS1_k127_5330079_4	580332.Slit_2837	1.156e-92	312.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2WCG6@28216|Betaproteobacteria,44W0X@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5330079_5	580332.Slit_0053	1.843e-66	227.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,44VXF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
REGS1_k127_5330079_1	395494.Galf_0057	2.435e-251	782.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,44V06@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_5392492_34	1121004.ATVC01000003_gene521	6.18e-07	51.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,2VHQN@28216|Betaproteobacteria,2KQ2K@206351|Neisseriales	206351|Neisseriales	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
REGS1_k127_5392492_12	580332.Slit_0774	3.894e-78	262.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,2VQ0A@28216|Betaproteobacteria,44VY2@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
REGS1_k127_5392492_28	580332.Slit_0775	2.636e-25	106.0	COG0255@1|root,COG0255@2|Bacteria,1Q0ZP@1224|Proteobacteria,2WAPV@28216|Betaproteobacteria,44WN1@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
REGS1_k127_5392492_23	580332.Slit_0776	3.042e-40	150.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,2VU2G@28216|Betaproteobacteria,44VZD@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
REGS1_k127_5392492_17	580332.Slit_0777	3.307e-70	238.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,2VR2N@28216|Betaproteobacteria,44VU6@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
REGS1_k127_5392492_21	580332.Slit_0778	2.162e-51	183.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2VUC6@28216|Betaproteobacteria,44W10@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
REGS1_k127_5392492_8	580332.Slit_0779	6.42e-105	343.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,2VHCP@28216|Betaproteobacteria,44V6G@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
REGS1_k127_5392492_22	580332.Slit_0780	1.587e-50	180.0	COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,2VSVX@28216|Betaproteobacteria,44VZE@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
REGS1_k127_5392492_14	580332.Slit_0781	7.172e-73	246.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,2VRBD@28216|Betaproteobacteria,44VUF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
REGS1_k127_5392492_9	580332.Slit_0782	1.057e-96	317.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,2VQ4W@28216|Betaproteobacteria,44VQK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
REGS1_k127_5392492_20	580332.Slit_0783	1.655e-58	205.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,2VSH0@28216|Betaproteobacteria,44W0K@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
REGS1_k127_5392492_10	580332.Slit_0784	2.723e-96	316.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,44VR0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
REGS1_k127_5392492_29	1485544.JQKP01000001_gene1128	2.826e-23	99.0	COG1841@1|root,COG1841@2|Bacteria,1N6ZE@1224|Proteobacteria,2VVPT@28216|Betaproteobacteria,44W34@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
REGS1_k127_5392492_13	580332.Slit_0786	1.431e-74	252.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,44VVB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
REGS1_k127_5392492_2	580332.Slit_0787	3.419e-263	812.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,2VHQH@28216|Betaproteobacteria,44VIZ@713636|Nitrosomonadales	28216|Betaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
REGS1_k127_5392492_24	580332.Slit_0788	7.748e-39	145.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU9X@28216|Betaproteobacteria,44W0J@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
REGS1_k127_5392492_33	580332.Slit_0789	9.852e-16	78.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,2VXPQ@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
REGS1_k127_5392492_19	580332.Slit_0790	3.965e-68	232.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,2VR2K@28216|Betaproteobacteria,44VVQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
REGS1_k127_5392492_16	580332.Slit_0791	6.424e-72	243.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,44VTB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
REGS1_k127_5392492_7	580332.Slit_0792	3.201e-120	387.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,44VAX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
REGS1_k127_5392492_4	580332.Slit_0793	1.449e-187	589.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,44V49@713636|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
REGS1_k127_5392492_18	580332.Slit_0794	2.435e-69	237.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,44VXK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
REGS1_k127_5392492_26	580332.Slit_0795	4.443e-34	136.0	2E2UU@1|root,32XWR@2|Bacteria,1N192@1224|Proteobacteria,2VUA1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5392492_27	580332.Slit_0796	4.55e-26	116.0	2ED0C@1|root,336XB@2|Bacteria,1ND2K@1224|Proteobacteria,2VXBS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5392492_11	580332.Slit_0797	1.26e-82	282.0	COG2340@1|root,COG2340@2|Bacteria,1RI4E@1224|Proteobacteria,2VX53@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.	-	-	-	-	-	-	-	-	-	-	-	-	CAP
REGS1_k127_5392492_0	580332.Slit_0798	0.0	1775.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,44VAW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
REGS1_k127_5392492_31	1499686.BN1079_00796	2.1e-21	96.0	COG5302@1|root,COG5302@2|Bacteria,1NIFA@1224|Proteobacteria,1SD2V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid	ccdA	-	-	ko:K19164	-	-	-	-	ko00000,ko02048	-	-	-	CcdA
REGS1_k127_5392492_25	1123368.AUIS01000019_gene1228	1.096e-34	136.0	2DNNV@1|root,32YCB@2|Bacteria,1N7IN@1224|Proteobacteria,1S9V9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM CcdB protein	ccdB	-	-	ko:K19163	-	-	-	-	ko00000,ko02048	-	-	-	CcdB
REGS1_k127_5392492_30	743299.Acife_3122	1.744e-22	99.0	COG4453@1|root,COG4453@2|Bacteria,1NFP8@1224|Proteobacteria,1SEJE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1778)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1778
REGS1_k127_5392492_3	314275.MADE_1016850	5.465e-251	785.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,1RRVF@1236|Gammaproteobacteria,464SA@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	HsdM N-terminal domain	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
REGS1_k127_5392492_15	520709.F985_03813	1.551e-72	259.0	COG0732@1|root,COG0732@2|Bacteria,1Q4FB@1224|Proteobacteria,1S2MB@1236|Gammaproteobacteria,3NSKN@468|Moraxellaceae	1236|Gammaproteobacteria	V	Type I restriction modification DNA specificity domain	hsdS	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
REGS1_k127_5392492_1	314275.MADE_1016840	0.0	1322.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,465IV@72275|Alteromonadaceae	1236|Gammaproteobacteria	L	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,Helicase_C,ResIII
REGS1_k127_5392492_6	1163408.UU9_09042	5.48e-141	452.0	COG5380@1|root,COG5380@2|Bacteria,1QG74@1224|Proteobacteria	1224|Proteobacteria	O	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
REGS1_k127_5392492_5	330214.NIDE2620	1.082e-171	541.0	COG4096@1|root,COG4096@2|Bacteria,3J18J@40117|Nitrospirae	2|Bacteria	L	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
REGS1_k127_5507122_0	580332.Slit_1579	0.0	1227.0	COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1QU8R@1224|Proteobacteria,2WHYG@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
REGS1_k127_5507122_2	580332.Slit_1580	2.046e-168	531.0	COG0559@1|root,COG0559@2|Bacteria,1N0XX@1224|Proteobacteria,2VME0@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_5507122_1	580332.Slit_1581	9.528e-225	700.0	COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria,2VHQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_5507122_3	1121035.AUCH01000001_gene1772	1.944e-54	199.0	COG2860@1|root,COG2860@2|Bacteria,1RHQN@1224|Proteobacteria,2VR9D@28216|Betaproteobacteria,2M021@206389|Rhodocyclales	206389|Rhodocyclales	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
REGS1_k127_5507122_4	580332.Slit_1755	1.126e-06	57.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,2VJ71@28216|Betaproteobacteria,44VBJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	FtsJ-like methyltransferase	rlmM	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
REGS1_k127_5566877_3	580332.Slit_0496	7.058e-28	114.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR7N@28216|Betaproteobacteria	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_5566877_0	580332.Slit_0499	1.279e-267	841.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	general secretion pathway protein D	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
REGS1_k127_5566877_1	580332.Slit_0498	1.957e-261	812.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
REGS1_k127_5566877_2	580332.Slit_0497	5.439e-97	327.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,44VBF@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Type II secretion system F domain	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
REGS1_k127_5591412_4	580332.Slit_2888	1.366e-82	277.0	COG1087@1|root,COG1087@2|Bacteria,1QYRM@1224|Proteobacteria,2WHYI@28216|Betaproteobacteria	28216|Betaproteobacteria	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5591412_2	344747.PM8797T_05845	3.621e-93	317.0	COG1216@1|root,COG1216@2|Bacteria,2IZF5@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
REGS1_k127_5591412_3	344747.PM8797T_05850	4.8e-92	309.0	COG1216@1|root,COG1216@2|Bacteria,2IZV9@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_5591412_5	1485544.JQKP01000002_gene1469	5.646e-82	287.0	COG3307@1|root,COG3307@2|Bacteria,1R495@1224|Proteobacteria,2VKCN@28216|Betaproteobacteria	28216|Betaproteobacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
REGS1_k127_5591412_0	580332.Slit_2880	9.126e-307	951.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria,44VNM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM polysaccharide biosynthesis protein CapD	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
REGS1_k127_5591412_1	580332.Slit_2881	1.597e-166	527.0	COG0472@1|root,COG0472@2|Bacteria,1MWYW@1224|Proteobacteria,2VNAG@28216|Betaproteobacteria,44VBI@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM Glycosyl transferase, family 4, conserved region	wbiH	-	-	ko:K13007	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
REGS1_k127_5591412_6	395494.Galf_2832	1.782e-23	99.0	COG0381@1|root,COG0381@2|Bacteria,1MWZN@1224|Proteobacteria,2VJ5C@28216|Betaproteobacteria,44WNS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the UDP-N-acetylglucosamine 2-epimerase family	wecB1	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
REGS1_k127_5618400_0	580332.Slit_2741	1.222e-266	824.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,44VCY@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
REGS1_k127_5618400_2	580332.Slit_2742	3.091e-137	438.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,44VFS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
REGS1_k127_5618400_1	580332.Slit_2743	2.057e-227	707.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,44UZX@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
REGS1_k127_5666944_0	580332.Slit_1879	1.022e-133	428.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VKFG@28216|Betaproteobacteria,44VP1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
REGS1_k127_5666944_1	1173264.KI913949_gene572	3.918e-83	280.0	COG0625@1|root,COG0625@2|Bacteria	2|Bacteria	O	glutathione transferase activity	yfcF	GO:0000302,GO:0003674,GO:0003824,GO:0004364,GO:0006950,GO:0006979,GO:0008150,GO:0009636,GO:0010035,GO:0016740,GO:0016765,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050896,GO:1901700	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	iECW_1372.ECW_m2490,iWFL_1372.ECW_m2490	GST_C_4,GST_N,GST_N_3
REGS1_k127_5666944_2	522306.CAP2UW1_1849	1.298e-82	280.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2VQH1@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	creB	-	-	ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_5666944_3	1121035.AUCH01000005_gene233	4.906e-23	102.0	COG0642@1|root,COG2205@2|Bacteria,1N17V@1224|Proteobacteria,2VH7Q@28216|Betaproteobacteria,2KVP8@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
REGS1_k127_569609_4	580332.Slit_1442	6.046e-167	525.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,44VFW@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
REGS1_k127_569609_2	580332.Slit_1441	6.025e-209	654.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,44W5Q@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	pilT2	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_569609_12	580332.Slit_1440	1.293e-59	208.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2VUB7@28216|Betaproteobacteria,44W1U@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ArsC family	yffB	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
REGS1_k127_569609_1	580332.Slit_1439	7.546e-216	673.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,44VKT@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_569609_5	580332.Slit_1438	2.376e-149	477.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,44VM3@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue	prmB	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
REGS1_k127_569609_6	580332.Slit_1437	6.333e-143	457.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,44VE7@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
REGS1_k127_569609_9	1120999.JONM01000005_gene3774	2.141e-119	389.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,2KPBY@206351|Neisseriales	206351|Neisseriales	I	Squalene synthase HpnD	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
REGS1_k127_569609_3	580332.Slit_1435	1.357e-206	653.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,44V02@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin containing amine oxidoreductase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
REGS1_k127_569609_8	580332.Slit_1433	2.007e-123	401.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,44UZS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
REGS1_k127_569609_11	580332.Slit_1432	3.022e-70	241.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420,ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	Abi,HTH_Crp_2,PrsW-protease,cNMP_binding
REGS1_k127_569609_7	580332.Slit_1430	1.548e-125	408.0	COG1192@1|root,COG1192@2|Bacteria,1N3GB@1224|Proteobacteria,2VSGK@28216|Betaproteobacteria,44VBZ@713636|Nitrosomonadales	28216|Betaproteobacteria	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
REGS1_k127_569609_13	580332.Slit_1429	1.323e-24	104.0	2DGZJ@1|root,2ZXVD@2|Bacteria,1PA8Z@1224|Proteobacteria,2W5F6@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_569609_10	640081.Dsui_1899	2.889e-102	340.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,2KV2Q@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
REGS1_k127_569609_0	580332.Slit_1427	4.789e-223	693.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,44UYF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
REGS1_k127_5737587_16	580332.Slit_0501	5.214e-34	132.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,44VR9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
REGS1_k127_5737587_14	580332.Slit_0485	6.277e-46	172.0	2DG9F@1|root,32U6V@2|Bacteria,1N0HX@1224|Proteobacteria,2VTXA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
REGS1_k127_5737587_7	580332.Slit_0484	2.117e-129	418.0	COG0745@1|root,COG0745@2|Bacteria,1PFQS@1224|Proteobacteria,2W982@28216|Betaproteobacteria,44WHJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Two component transcriptional regulator, winged helix family	-	-	-	ko:K02483,ko:K07662	ko01503,ko02020,map01503,map02020	M00447,M00727,M00728	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_5737587_4	580332.Slit_0483	3.442e-196	621.0	COG0642@1|root,COG2205@2|Bacteria,1PFQP@1224|Proteobacteria,2W8ZK@28216|Betaproteobacteria,44WJR@713636|Nitrosomonadales	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07711	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_5737587_6	580332.Slit_0482	2.227e-136	437.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,44V22@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
REGS1_k127_5737587_8	580332.Slit_0481	6.611e-126	409.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,44VDB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
REGS1_k127_5737587_2	580332.Slit_0479	3.242e-267	828.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,2VI29@28216|Betaproteobacteria,44W65@713636|Nitrosomonadales	28216|Betaproteobacteria	P	MgtE intracellular N domain	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
REGS1_k127_5737587_0	1485544.JQKP01000001_gene1165	0.0	1551.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44VNU@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	acrD4	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
REGS1_k127_5737587_9	1485544.JQKP01000001_gene1164	1.443e-112	374.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K18306	ko02024,map02024	M00644	-	-	ko00000,ko00001,ko00002,ko02000	2.A.6.2.20,2.A.6.2.32,8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_5737587_3	580332.Slit_0475	6.135e-236	738.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,2VI3M@28216|Betaproteobacteria,44VK2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
REGS1_k127_5737587_5	580332.Slit_0474	5.738e-161	520.0	COG1965@1|root,COG3577@1|root,COG1965@2|Bacteria,COG3577@2|Bacteria	2|Bacteria	S	aspartic-type endopeptidase activity	cyaY	GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564	1.16.3.1	ko:K06202,ko:K06985,ko:K19054	ko00860,ko04112,map00860,map04112	-	R00078	RC02758	ko00000,ko00001,ko01000,ko03029	-	-	iECW_1372.ECW_m4108,iEKO11_1354.EKO11_4552,iWFL_1372.ECW_m4108	Frataxin_Cyay,gag-asp_proteas
REGS1_k127_5737587_15	580332.Slit_0473	1.436e-38	147.0	COG1965@1|root,COG1965@2|Bacteria,1RH9A@1224|Proteobacteria,2VVS3@28216|Betaproteobacteria,44W1B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Frataxin-like domain	cyaY	-	-	ko:K06202	-	-	-	-	ko00000	-	-	-	Frataxin_Cyay
REGS1_k127_5737587_10	580332.Slit_0472	2.525e-111	364.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,44VS3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
REGS1_k127_5737587_11	580332.Slit_0471	1.409e-99	330.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,44VFK@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Phosphate acyltransferases	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_5737587_12	580332.Slit_0470	5.45e-94	311.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,44VFT@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Polynucleotide kinase 3 phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_like,PNK3P
REGS1_k127_5737587_1	580332.Slit_0469	0.0	1189.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,44VBX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
REGS1_k127_5737587_13	580332.Slit_0468	1.194e-86	287.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria,44VDK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
REGS1_k127_5777543_2	1485544.JQKP01000001_gene1097	9.463e-99	331.0	COG1450@1|root,COG1450@2|Bacteria,1MVNC@1224|Proteobacteria,2VMT1@28216|Betaproteobacteria,44V3S@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II and III secretion system protein	exeD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N_2
REGS1_k127_5777543_0	580332.Slit_0688	8.965e-201	639.0	COG3266@1|root,COG3267@1|root,COG3266@2|Bacteria,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,2W9RR@28216|Betaproteobacteria,44WF1@713636|Nitrosomonadales	28216|Betaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
REGS1_k127_5777543_1	580332.Slit_0689	4.472e-121	393.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2W994@28216|Betaproteobacteria,44WD7@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
REGS1_k127_5801944_2	497321.C664_10373	1.575e-81	275.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,2VSFW@28216|Betaproteobacteria,2KWV1@206389|Rhodocyclales	206389|Rhodocyclales	S	Acyl carrier protein phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
REGS1_k127_5801944_0	338969.Rfer_3972	1.24e-178	564.0	COG4990@1|root,COG4990@2|Bacteria,1MVC4@1224|Proteobacteria,2VJT2@28216|Betaproteobacteria,4ACVE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Butirosin biosynthesis protein H, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
REGS1_k127_5801944_3	338969.Rfer_3973	2.378e-53	197.0	2CE7N@1|root,30Q80@2|Bacteria,1MZ6U@1224|Proteobacteria,2VSFG@28216|Betaproteobacteria,4AFAC@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5801944_1	580332.Slit_0359	1.07e-96	318.0	COG0332@1|root,COG0332@2|Bacteria,1NAGY@1224|Proteobacteria,2VK97@28216|Betaproteobacteria,44WA7@713636|Nitrosomonadales	28216|Betaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III_C,ketoacyl-synt
REGS1_k127_5810593_1	580332.Slit_2467	8.025e-70	239.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2W931@28216|Betaproteobacteria,44WM2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_5810593_2	580332.Slit_2466	9.715e-59	208.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,44WG1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
REGS1_k127_5810593_0	580332.Slit_2465	1.878e-139	444.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,44WCP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
REGS1_k127_5823864_16	338969.Rfer_3547	2.808e-11	64.0	COG2199@1|root,COG3706@2|Bacteria,1R5N6@1224|Proteobacteria,2VJQU@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_5823864_7	580332.Slit_1537	3.987e-138	441.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,44V7Z@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TatD related DNase	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
REGS1_k127_5823864_2	580332.Slit_1536	8.4e-182	572.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,44VBK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
REGS1_k127_5823864_8	580332.Slit_1535	3.668e-108	353.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,44VRC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
REGS1_k127_5823864_5	580332.Slit_1534	2.698e-143	460.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,44VGR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
REGS1_k127_5823864_10	1485544.JQKP01000013_gene1820	3.566e-76	263.0	COG0115@1|root,COG0115@2|Bacteria,1MZAK@1224|Proteobacteria,2VRAS@28216|Betaproteobacteria,44VRZ@713636|Nitrosomonadales	28216|Betaproteobacteria	EH	Amino-transferase class IV	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
REGS1_k127_5823864_0	580332.Slit_1532	4.926e-237	736.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,44V9T@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_5823864_13	580332.Slit_1531	1.384e-36	139.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,44VYH@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_5823864_6	580332.Slit_1530	6.017e-139	444.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,44VP6@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	KR domain	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_5823864_3	580332.Slit_1529	1.108e-179	565.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,44V99@713636|Nitrosomonadales	28216|Betaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K13935,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
REGS1_k127_5823864_4	580332.Slit_1528	1.104e-171	542.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,44VNK@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_5823864_1	580332.Slit_1527	4.081e-191	601.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,44VJN@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
REGS1_k127_5823864_14	580332.Slit_1526	1.123e-31	123.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,44W39@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
REGS1_k127_5823864_12	580332.Slit_1525	1.783e-54	196.0	COG1399@1|root,COG1399@2|Bacteria,1PIWK@1224|Proteobacteria,2W7FZ@28216|Betaproteobacteria,44VYP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
REGS1_k127_5823864_9	580332.Slit_1524	2.09e-83	281.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,44VRW@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
REGS1_k127_5823864_11	580332.Slit_1523	4.609e-74	252.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VQR5@28216|Betaproteobacteria,44VXB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
REGS1_k127_5823864_17	637389.Acaty_c1804	1.174e-09	69.0	COG3637@1|root,COG3637@2|Bacteria,1NG4D@1224|Proteobacteria,1SR3J@1236|Gammaproteobacteria,2NDZJ@225057|Acidithiobacillales	1236|Gammaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5823864_15	653733.Selin_1273	5.625e-31	126.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	OprB,PorP_SprF,SLH,Toluene_X
REGS1_k127_5827783_7	1245471.PCA10_49940	1.443e-34	143.0	2DM2X@1|root,31HF3@2|Bacteria,1RIYM@1224|Proteobacteria,1TBIG@1236|Gammaproteobacteria,1YHQY@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5827783_0	1163617.SCD_n02809	1.909e-241	757.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	-	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
REGS1_k127_5827783_2	1123368.AUIS01000016_gene2552	2.652e-144	470.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RNV0@1236|Gammaproteobacteria,2NCMQ@225057|Acidithiobacillales	1236|Gammaproteobacteria	NU	PFAM type II secretion system	pilC	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
REGS1_k127_5827783_3	323848.Nmul_A2590	1.623e-63	222.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR66@28216|Betaproteobacteria,37356@32003|Nitrosomonadales	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_5827783_6	1163617.SCD_n02834	2.525e-42	161.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,2VU7P@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type II secretory pathway, pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5827783_5	580332.Slit_1823	2.082e-42	159.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria,44WJA@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_5827783_4	666681.M301_0467	8.996e-56	200.0	COG4968@1|root,COG4968@2|Bacteria,1QVCD@1224|Proteobacteria,2WGQ3@28216|Betaproteobacteria,2KMZU@206350|Nitrosomonadales	206350|Nitrosomonadales	U	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
REGS1_k127_5827783_1	1144319.PMI16_01877	2.132e-229	732.0	COG4796@1|root,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,472RY@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Secretin and TonB N terminus short domain	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Cohesin,STN,Secretin,Secretin_N
REGS1_k127_5827783_9	580332.Slit_1826	3.887e-22	102.0	2E5FR@1|root,3307F@2|Bacteria,1N89J@1224|Proteobacteria,2VVS4@28216|Betaproteobacteria,44WJM@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5827783_8	1144319.PMI16_01875	3.521e-34	138.0	COG3167@1|root,COG3167@2|Bacteria,1NKE0@1224|Proteobacteria,2VXXU@28216|Betaproteobacteria,4787S@75682|Oxalobacteraceae	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	-	-	-	-	-	-	-	-	-	PilO
REGS1_k127_5836509_1	580332.Slit_0181	5.881e-250	771.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,44VAJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
REGS1_k127_5836509_2	580332.Slit_0183	3.888e-244	762.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,44VJM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
REGS1_k127_5836509_0	580332.Slit_0184	4.483e-250	776.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,44VNF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_5836509_3	1163617.SCD_n00490	5.151e-43	158.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
REGS1_k127_5836509_4	580332.Slit_0187	5.563e-28	113.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,44VNT@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
REGS1_k127_5881064_2	580332.Slit_0187	2.119e-227	706.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,44VNT@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
REGS1_k127_5881064_10	663321.REG_0561	0.0001373	48.0	COG1484@1|root,COG4584@1|root,COG1484@2|Bacteria,COG4584@2|Bacteria,1MU2G@1224|Proteobacteria,1RQA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,rve
REGS1_k127_5881064_9	1121121.KB894333_gene4598	1.117e-06	52.0	2ED1A@1|root,336Y8@2|Bacteria,1VNP3@1239|Firmicutes,4HRCX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5881064_3	1485544.JQKP01000007_gene2008	2.915e-157	501.0	COG0582@1|root,COG0582@2|Bacteria,1QB64@1224|Proteobacteria,2W8R9@28216|Betaproteobacteria,44WM9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
REGS1_k127_5881064_6	666681.M301_0131	7.551e-41	160.0	COG2944@1|root,COG2944@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K18830	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
REGS1_k127_5881064_5	666681.M301_0132	4.582e-76	271.0	2D784@1|root,32TNH@2|Bacteria,1N098@1224|Proteobacteria,2VX0M@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5881064_4	1541065.JRFE01000062_gene5907	1.412e-81	280.0	2BXU9@1|root,32R22@2|Bacteria,1G7ES@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF3800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
REGS1_k127_5881064_1	580332.Slit_0252	4.639e-303	942.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_5881064_0	580332.Slit_0253	0.0	1331.0	COG0457@1|root,COG1305@1|root,COG3391@1|root,COG4733@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,1R42S@1224|Proteobacteria	1224|Proteobacteria	E	fibronectin type III domain protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_5907932_1	580332.Slit_0060	1.123e-174	548.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,44V3A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation region	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
REGS1_k127_5907932_5	671143.DAMO_1279	5.615e-05	53.0	2ECDB@1|root,336BJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5907932_2	580332.Slit_0058	1.134e-138	441.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,44VE1@713636|Nitrosomonadales	28216|Betaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_5907932_4	395494.Galf_0063	3.922e-59	209.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,44WGS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_5907932_3	580332.Slit_2980	2.348e-71	243.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,44VV1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
REGS1_k127_5907932_0	580332.Slit_2981	3.944e-243	752.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,44V86@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
REGS1_k127_5930683_2	580332.Slit_2061	2.196e-179	564.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,44VC3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
REGS1_k127_5930683_0	580332.Slit_2060	0.0	1077.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,44V1X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
REGS1_k127_5930683_6	580332.Slit_2059	9.153e-50	178.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,44VZM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_5930683_7	580332.Slit_2058	2.823e-32	129.0	COG5416@1|root,COG5416@2|Bacteria,1N4UI@1224|Proteobacteria,2VU63@28216|Betaproteobacteria,44W2U@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pfam:DUF1049	-	-	-	ko:K08992	-	-	-	-	ko00000	-	-	-	LapA_dom
REGS1_k127_5930683_1	580332.Slit_2057	4.272e-206	645.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,44UYA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_7
REGS1_k127_5930683_5	580332.Slit_2056	8.322e-111	364.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria,44VEZ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
REGS1_k127_5930683_3	580332.Slit_2055	6.492e-171	546.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,2VHNS@28216|Betaproteobacteria,44VK8@713636|Nitrosomonadales	28216|Betaproteobacteria	M	pfkB family carbohydrate kinase	rfaE	-	2.7.1.167,2.7.7.70	ko:K03272,ko:K21344	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
REGS1_k127_5930683_4	580332.Slit_2054	1.878e-140	448.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,44V6M@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
REGS1_k127_5950962_2	580332.Slit_0672	1.182e-75	259.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,44V9I@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
REGS1_k127_5950962_0	580332.Slit_0673	0.0	1097.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,44V1S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
REGS1_k127_5950962_8	580332.Slit_2153	1.38e-26	119.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,44W1F@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_5950962_1	580332.Slit_0675	1.902e-259	804.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,44VP0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
REGS1_k127_5950962_4	1485544.JQKP01000001_gene1089	5.326e-55	201.0	COG2165@1|root,COG2165@2|Bacteria,1RHE1@1224|Proteobacteria,2VSJ6@28216|Betaproteobacteria,44W1C@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	general secretion pathway protein	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
REGS1_k127_5950962_5	1112274.KI911560_gene1251	2.63e-40	166.0	2DNAT@1|root,32WH7@2|Bacteria,1QWGY@1224|Proteobacteria,2WGZE@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5950962_7	580332.Slit_0681	7.803e-28	119.0	2A8Z0@1|root,30Y2T@2|Bacteria,1PJYF@1224|Proteobacteria,2W8A2@28216|Betaproteobacteria,44WNZ@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5950962_3	580332.Slit_0682	4.822e-68	239.0	2BUX7@1|root,32Q9G@2|Bacteria,1PJYB@1224|Proteobacteria,2W8A0@28216|Betaproteobacteria,44WNV@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5950962_6	580332.Slit_0683	1.053e-32	128.0	2CG4C@1|root,2Z8MQ@2|Bacteria,1R6PQ@1224|Proteobacteria,2VHKG@28216|Betaproteobacteria,44WGT@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5952321_0	580332.Slit_1345	2.743e-172	542.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,44V2A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
REGS1_k127_5952321_1	580332.Slit_1346	4.68e-116	374.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,44VV7@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
REGS1_k127_5952321_2	1502770.JQMG01000001_gene535	3.74e-93	336.0	COG2199@1|root,COG2202@1|root,COG5001@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
REGS1_k127_5952321_3	1173028.ANKO01000168_gene4365	2.81e-39	169.0	COG0642@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1FZYQ@1117|Cyanobacteria,1H8X5@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_5952321_4	402777.KB235903_gene1837	2.054e-22	98.0	COG0467@1|root,COG0467@2|Bacteria,1G2R3@1117|Cyanobacteria,1HA0C@1150|Oscillatoriales	1117|Cyanobacteria	T	in signal transduction	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
REGS1_k127_5971165_1	261292.Nit79A3_3068	5.744e-183	586.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	DHOR
REGS1_k127_5971165_6	330214.NIDE2826	6.55e-63	231.0	COG1459@1|root,COG1459@2|Bacteria,3J0HZ@40117|Nitrospirae	40117|Nitrospirae	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
REGS1_k127_5971165_0	443143.GM18_1138	5.696e-191	613.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WTUB@28221|Deltaproteobacteria,43T1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-1	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
REGS1_k127_5971165_2	648757.Rvan_1818	3.265e-105	370.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2TY55@28211|Alphaproteobacteria	28211|Alphaproteobacteria	U	Bacterial type II and III secretion system protein	pilQ	-	-	ko:K02453,ko:K02666	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	Secretin,Secretin_N
REGS1_k127_5971165_9	338966.Ppro_2414	6.665e-36	142.0	COG2165@1|root,COG2165@2|Bacteria,1RGZZ@1224|Proteobacteria,4303Z@68525|delta/epsilon subdivisions,2WVCX@28221|Deltaproteobacteria,43V07@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Prokaryotic N-terminal methylation motif	pulG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
REGS1_k127_5971165_10	322710.Avin_29080	4.539e-31	129.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,1S8T4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	U	Type II secretion system protein G	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_5971165_8	555779.Dthio_PD2708	3.603e-42	160.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2MCQM@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	PFAM type II secretion system protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_5971165_11	1268068.PG5_14140	2.755e-26	115.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,1SBEY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Type II secretory pathway pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5971165_13	580332.Slit_2045	5.712e-19	86.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VW9W@28216|Betaproteobacteria,44WPG@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_5971165_12	580332.Slit_2044	6.787e-20	89.0	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria,44WNR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5971165_14	637390.AFOH01000120_gene556	5.831e-13	69.0	COG0384@1|root,COG0384@2|Bacteria,1R9X4@1224|Proteobacteria,1RZ0R@1236|Gammaproteobacteria,2NCTG@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
REGS1_k127_5971165_4	580332.Slit_1760	6.79e-80	269.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,44VTI@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
REGS1_k127_5971165_7	887062.HGR_11700	9.612e-47	170.0	COG3759@1|root,COG3759@2|Bacteria,1MZ4F@1224|Proteobacteria,2VUPP@28216|Betaproteobacteria,4AEWT@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF1304)	-	-	-	ko:K08987	-	-	-	-	ko00000	-	-	-	DUF1304
REGS1_k127_5971165_5	316067.Geob_3253	5.134e-64	235.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_5971165_3	580332.Slit_1759	1.461e-99	327.0	COG0729@1|root,COG0729@2|Bacteria,1QVQI@1224|Proteobacteria,2W0WR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5993829_1	580332.Slit_2978	3.86e-185	580.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,44VF7@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
REGS1_k127_5993829_0	580332.Slit_2976	1.024e-294	908.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,44V6Y@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
REGS1_k127_5993829_2	1485544.JQKP01000001_gene919	1.682e-98	326.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,44VJS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM import inner membrane translocase subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
REGS1_k127_6028231_21	580332.Slit_2468	1.345e-49	178.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,2VTYD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
REGS1_k127_6028231_25	580332.Slit_2471	3.698e-31	123.0	2DJVG@1|root,307GH@2|Bacteria,1RG4V@1224|Proteobacteria,2VS8I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
REGS1_k127_6028231_22	1038869.AXAN01000053_gene726	6.361e-38	145.0	COG2076@1|root,COG2076@2|Bacteria,1NHR2@1224|Proteobacteria,2VXSA@28216|Betaproteobacteria,1K9SK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_6028231_5	1038869.AXAN01000053_gene727	7.876e-142	456.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,2VIE6@28216|Betaproteobacteria,1K5J5@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_6028231_12	580332.Slit_2472	9.604e-115	374.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,44W6B@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
REGS1_k127_6028231_18	580332.Slit_2473	2.664e-73	249.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,2VR62@28216|Betaproteobacteria,44VTK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	OsmC-like protein	yhfA	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
REGS1_k127_6028231_10	580332.Slit_2474	1.656e-118	383.0	COG2941@1|root,COG2941@2|Bacteria,1RAA1@1224|Proteobacteria,2VQRE@28216|Betaproteobacteria,44V79@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol	coq7	-	-	ko:K06134	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R04984,R08775	RC01254	ko00000,ko00001,ko00002,ko01000	-	-	-	COQ7
REGS1_k127_6028231_16	580332.Slit_2477	1.935e-83	290.0	COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria	1224|Proteobacteria	M	Outer membrane protein (Porin)	-	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03285	-	-	-	-	ko00000	1.B.1	-	-	Porin_4
REGS1_k127_6028231_14	580332.Slit_2478	2.521e-90	309.0	COG3203@1|root,COG3203@2|Bacteria,1MWUN@1224|Proteobacteria,2VT8P@28216|Betaproteobacteria,44VYA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM porin Gram-negative type	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
REGS1_k127_6028231_11	580332.Slit_2505	4.643e-118	405.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,44V9E@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
REGS1_k127_6028231_4	580332.Slit_2506	9.334e-232	722.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,44V7E@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_6028231_27	269796.Rru_A2995	1.978e-21	98.0	2DVSG@1|root,32V02@2|Bacteria,1N360@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6028231_13	686340.Metal_0741	1.409e-93	322.0	COG0455@1|root,COG0455@2|Bacteria	2|Bacteria	D	bacterial-type flagellum organization	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CBP_BcsQ,CbiA,ParA,TPR_2,TPR_8
REGS1_k127_6028231_9	686340.Metal_0740	1.781e-120	402.0	COG1192@1|root,COG1192@2|Bacteria,1MX85@1224|Proteobacteria,1RSBA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	Involved in chromosome partitioning	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6028231_1	395494.Galf_0424	5.87e-300	927.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,44V98@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
REGS1_k127_6028231_19	1485544.JQKP01000002_gene1666	8.969e-72	243.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,2VUM5@28216|Betaproteobacteria,44VVX@713636|Nitrosomonadales	28216|Betaproteobacteria	S	membrane	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_6028231_24	653733.Selin_2381	1.005e-35	145.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
REGS1_k127_6028231_15	580332.Slit_2625	2.954e-89	301.0	COG0627@1|root,COG0627@2|Bacteria,1MY73@1224|Proteobacteria,2VS12@28216|Betaproteobacteria,44WA1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
REGS1_k127_6028231_3	1485544.JQKP01000005_gene293	2.037e-273	851.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2VMB2@28216|Betaproteobacteria,44W3T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
REGS1_k127_6028231_6	580332.Slit_2627	5.19e-129	416.0	COG0726@1|root,COG0726@2|Bacteria,1PJQG@1224|Proteobacteria,2VIG8@28216|Betaproteobacteria,44WAA@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	-	-	3.5.1.41	ko:K01452	ko00520,ko01100,map00520,map01100	-	R02333	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
REGS1_k127_6028231_8	580332.Slit_2628	1.589e-121	394.0	COG1352@1|root,COG1352@2|Bacteria,1QVIR@1224|Proteobacteria,2WGT0@28216|Betaproteobacteria	28216|Betaproteobacteria	NT	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_6028231_7	395494.Galf_0224	5.762e-122	400.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,44VMG@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
REGS1_k127_6028231_20	580332.Slit_2611	3.528e-53	194.0	COG3807@1|root,COG3807@2|Bacteria,1MZIA@1224|Proteobacteria,2VUTD@28216|Betaproteobacteria,44W2W@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
REGS1_k127_6028231_17	580332.Slit_2612	2.135e-74	252.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,44VTN@713636|Nitrosomonadales	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
REGS1_k127_6028231_23	666681.M301_0572	1.616e-36	142.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,2KN2J@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
REGS1_k127_6028231_26	243159.AFE_2364	2.188e-26	113.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,1S8ZI@1236|Gammaproteobacteria,2NCVA@225057|Acidithiobacillales	225057|Acidithiobacillales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_6028231_2	580332.Slit_2615	5.021e-278	865.0	COG3307@1|root,COG3307@2|Bacteria,1RA1F@1224|Proteobacteria,2VQ8F@28216|Betaproteobacteria,44V2K@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Virulence factor membrane-bound polymerase, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PglL_A,Wzy_C,Wzy_C_2
REGS1_k127_6028231_28	743299.Acife_2416	5.288e-19	91.0	2ADNI@1|root,313DE@2|Bacteria,1QCY3@1224|Proteobacteria,1T8S4@1236|Gammaproteobacteria,2NDBY@225057|Acidithiobacillales	225057|Acidithiobacillales	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
REGS1_k127_6028231_0	580332.Slit_2617	0.0	1397.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,44VJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_6037035_1	1288494.EBAPG3_25000	2.797e-117	400.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,374RC@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
REGS1_k127_6037035_2	1408419.JHYG01000013_gene2090	1.129e-32	132.0	COG4251@1|root,COG4251@2|Bacteria,1N1KJ@1224|Proteobacteria,2UD2F@28211|Alphaproteobacteria,2JXKX@204441|Rhodospirillales	204441|Rhodospirillales	T	KaiB domain	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
REGS1_k127_6037035_0	1159870.KB907784_gene2606	2.121e-238	748.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,2VIKV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
REGS1_k127_6049971_2	580332.Slit_2122	9.739e-64	219.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,44VCP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_6049971_1	580332.Slit_2123	4.322e-125	401.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,44V73@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
REGS1_k127_6049971_4	1123393.KB891316_gene1198	4.691e-24	104.0	29246@1|root,2ZPP6@2|Bacteria,1PARR@1224|Proteobacteria,2W68C@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6049971_0	395494.Galf_0490	4.728e-264	819.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,44V0G@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
REGS1_k127_6049971_3	1348657.M622_11625	6.092e-52	189.0	COG1943@1|root,COG1943@2|Bacteria,1P19I@1224|Proteobacteria,2VKZ3@28216|Betaproteobacteria,2KX0Z@206389|Rhodocyclales	206389|Rhodocyclales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
REGS1_k127_6084125_2	395494.Galf_0140	2.238e-22	96.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,44VA6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
REGS1_k127_6084125_1	580332.Slit_2929	1.297e-62	219.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Pfam Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
REGS1_k127_6084125_0	395494.Galf_0139	0.0	1077.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,44VER@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
REGS1_k127_6128533_1	580332.Slit_2419	4.168e-135	435.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,44W8A@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM AIR synthase related protein domain protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
REGS1_k127_6128533_3	243233.MCA0550	2.087e-43	162.0	COG2189@1|root,COG2852@1|root,COG2189@2|Bacteria,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SA4A@1236|Gammaproteobacteria,1XFUA@135618|Methylococcales	135618|Methylococcales	L	Protein of unknown function (DUF559)	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
REGS1_k127_6128533_6	1485544.JQKP01000020_gene55	3.373e-06	51.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,44V8V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	rmlA	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
REGS1_k127_6128533_0	580332.Slit_2421	3.741e-216	675.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,2VHKM@28216|Betaproteobacteria,44W7R@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
REGS1_k127_6128533_4	640081.Dsui_1160	3.004e-28	115.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,2VVZH@28216|Betaproteobacteria,2KX70@206389|Rhodocyclales	206389|Rhodocyclales	O	Hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
REGS1_k127_6128533_2	338969.Rfer_4097	2.217e-68	240.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,4AAIC@80864|Comamonadaceae	28216|Betaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Carbam_trans_N,Sua5_yciO_yrdC,zf-HYPF
REGS1_k127_6140012_2	395494.Galf_1932	2.644e-117	382.0	COG1225@1|root,COG1225@2|Bacteria,1MWFZ@1224|Proteobacteria,2W14Y@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_6140012_5	614083.AWQR01000009_gene530	7.613e-32	128.0	COG5460@1|root,COG5460@2|Bacteria,1PTUZ@1224|Proteobacteria,2VV0Z@28216|Betaproteobacteria,4AF9I@80864|Comamonadaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
REGS1_k127_6140012_1	580332.Slit_1782	8.152e-157	498.0	COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Response_reg
REGS1_k127_6140012_0	580332.Slit_1783	1.362e-229	719.0	COG0517@1|root,COG4191@1|root,COG0517@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,HATPase_c,HisKA,Response_reg,dCache_1
REGS1_k127_6140012_3	1237149.C900_05070	2.148e-93	322.0	2CF5E@1|root,2ZFJ4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
REGS1_k127_6140012_6	395494.Galf_1646	7.301e-22	96.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria,44W13@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
REGS1_k127_618400_3	580332.Slit_1970	3.402e-148	477.0	COG0845@1|root,COG0845@2|Bacteria,1QN99@1224|Proteobacteria,2VQR3@28216|Betaproteobacteria,44V5R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM efflux transporter, RND family, MFP subunit	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
REGS1_k127_618400_0	395494.Galf_1163	0.0	1709.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,44V2S@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
REGS1_k127_618400_6	395494.Galf_1162	5.756e-52	186.0	2EQBS@1|root,30WRI@2|Bacteria,1PWXX@1224|Proteobacteria,2WCFU@28216|Betaproteobacteria,44W00@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3240)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3240
REGS1_k127_618400_4	580332.Slit_1973	3.01e-147	479.0	COG1538@1|root,COG1538@2|Bacteria,1R9PU@1224|Proteobacteria,2VPEH@28216|Betaproteobacteria,44VFY@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_618400_7	395494.Galf_1160	4.052e-34	134.0	COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,2VVPU@28216|Betaproteobacteria,44VZK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
REGS1_k127_618400_1	580332.Slit_1976	0.0	1275.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,44V5I@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
REGS1_k127_618400_2	580332.Slit_1977	3.212e-190	613.0	COG0741@1|root,COG1388@1|root,COG3170@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,COG3170@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,44V2P@713636|Nitrosomonadales	28216|Betaproteobacteria	M	LysM domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
REGS1_k127_618400_5	580332.Slit_1981	1.013e-72	247.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,44V4B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	dppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
REGS1_k127_6185896_3	545264.KB898756_gene1621	0.0001383	51.0	COG3637@1|root,COG3637@2|Bacteria,1RJMJ@1224|Proteobacteria,1S7PC@1236|Gammaproteobacteria,1WZJW@135613|Chromatiales	135613|Chromatiales	M	OmpA-like transmembrane domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
REGS1_k127_6185896_0	1165096.ARWF01000001_gene557	1.654e-304	942.0	COG1944@1|root,COG1944@2|Bacteria,1MV7K@1224|Proteobacteria,2VHZY@28216|Betaproteobacteria,2KKTK@206350|Nitrosomonadales	206350|Nitrosomonadales	O	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC,YcaO
REGS1_k127_6185896_1	314345.SPV1_01352	5.574e-121	392.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_6217246_1	1485544.JQKP01000005_gene403	4.698e-137	438.0	COG0644@1|root,COG0644@2|Bacteria,1MZVI@1224|Proteobacteria,2VH6J@28216|Betaproteobacteria	28216|Betaproteobacteria	C	fad dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,Trp_halogenase
REGS1_k127_6217246_0	580332.Slit_0372	1.216e-151	486.0	COG0251@1|root,COG0251@2|Bacteria,1NQGP@1224|Proteobacteria,2VMPK@28216|Betaproteobacteria,44WCX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	pteridine-dependent deoxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
REGS1_k127_6217246_2	580332.Slit_0374	2.567e-119	388.0	COG0204@1|root,COG0204@2|Bacteria,1RDN7@1224|Proteobacteria,2VNX6@28216|Betaproteobacteria,44W4K@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
REGS1_k127_6217246_3	580332.Slit_0375	9.065e-116	375.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,2VKU3@28216|Betaproteobacteria,44W4I@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K00786	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
REGS1_k127_6223019_0	395494.Galf_1210	4.651e-263	818.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,44W5Y@713636|Nitrosomonadales	28216|Betaproteobacteria	P	K+ potassium transporter	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
REGS1_k127_6223019_10	460265.Mnod_7349	2.631e-58	221.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
REGS1_k127_6223019_13	580332.Slit_2475	2.832e-19	89.0	COG4634@1|root,COG4634@2|Bacteria,1NAN6@1224|Proteobacteria,2VVRB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6223019_9	1122915.AUGY01000055_gene536	2.579e-59	216.0	COG1266@1|root,COG1266@2|Bacteria,1UHWB@1239|Firmicutes,4IURF@91061|Bacilli,277Q3@186822|Paenibacillaceae	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
REGS1_k127_6223019_11	580332.Slit_2475	5.357e-56	199.0	COG4634@1|root,COG4634@2|Bacteria,1NAN6@1224|Proteobacteria,2VVRB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6223019_12	580332.Slit_2476	1.107e-36	140.0	COG2442@1|root,COG2442@2|Bacteria,1N7GJ@1224|Proteobacteria,2VWIS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
REGS1_k127_6223019_3	580332.Slit_2387	6.642e-179	569.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,44VPF@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
REGS1_k127_6223019_8	395494.Galf_2361	1.423e-78	275.0	2B3KG@1|root,31W9T@2|Bacteria,1PWY8@1224|Proteobacteria,2WCG4@28216|Betaproteobacteria,44W0P@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6223019_5	580332.Slit_2385	2.053e-111	369.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,44V40@713636|Nitrosomonadales	28216|Betaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
REGS1_k127_6223019_4	580332.Slit_2384	1.122e-111	366.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,44VGV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
REGS1_k127_6223019_2	580332.Slit_2383	2.416e-202	642.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6223019_7	1485544.JQKP01000004_gene494	2.988e-84	284.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,44VRU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
REGS1_k127_6223019_6	580332.Slit_2379	4.239e-94	310.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,2VSGZ@28216|Betaproteobacteria,44VT9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF615)	yjgA	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
REGS1_k127_6223019_1	580332.Slit_2378	3.437e-255	791.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,2VHJ4@28216|Betaproteobacteria,44VHH@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM peptidase U62 modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_6244379_2	580332.Slit_2203	5.766e-63	216.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,44VJZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_6244379_6	1441930.Z042_14465	1.264e-27	120.0	2C5CR@1|root,2ZKH4@2|Bacteria,1P75Y@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
REGS1_k127_6244379_1	665571.STHERM_c22460	4.951e-75	258.0	COG1136@1|root,COG1136@2|Bacteria,2J5PI@203691|Spirochaetes	203691|Spirochaetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_6244379_9	1167006.UWK_00539	1.636e-12	79.0	28IZT@1|root,2Z8X3@2|Bacteria,1R4RF@1224|Proteobacteria,42QV2@68525|delta/epsilon subdivisions,2WMYU@28221|Deltaproteobacteria,2MJR5@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6244379_7	305700.B447_02848	6.981e-17	90.0	COG2834@1|root,COG2834@2|Bacteria,1RE9C@1224|Proteobacteria,2VPGB@28216|Betaproteobacteria,2KVYY@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
REGS1_k127_6244379_3	909663.KI867150_gene764	2.798e-39	162.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42NUK@68525|delta/epsilon subdivisions,2WKP4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_6244379_5	1408473.JHXO01000005_gene1473	1.064e-28	130.0	COG4591@1|root,COG4591@2|Bacteria,4NGJ3@976|Bacteroidetes,2FS1D@200643|Bacteroidia	976|Bacteroidetes	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
REGS1_k127_6244379_8	1124780.ANNU01000019_gene1767	9.804e-14	78.0	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,47S7U@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
REGS1_k127_6244379_4	1040986.ATYO01000002_gene4213	1.57e-38	153.0	COG1309@1|root,COG1309@2|Bacteria,1NCT4@1224|Proteobacteria,2UGEC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_6244379_0	395494.Galf_1809	4.782e-78	262.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,44VJZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_6245349_6	1116472.MGMO_96c00150	2.091e-18	85.0	COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria,1XFER@135618|Methylococcales	135618|Methylococcales	M	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
REGS1_k127_6245349_5	1134474.O59_002886	2.795e-21	94.0	2E4YG@1|root,32ZSB@2|Bacteria,1N74T@1224|Proteobacteria,1TB8R@1236|Gammaproteobacteria,1FIGQ@10|Cellvibrio	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3309)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3309
REGS1_k127_6245349_4	395494.Galf_2212	6.1e-30	121.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,44WIE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
REGS1_k127_6245349_7	1348657.M622_00745	4.377e-13	74.0	COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria,2KWJ8@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
REGS1_k127_6245349_1	1144343.PMI41_03760	9.749e-140	448.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,2TRUA@28211|Alphaproteobacteria,43JM2@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
REGS1_k127_6245349_0	1123508.JH636439_gene1093	8.647e-252	782.0	COG1858@1|root,COG1858@2|Bacteria,2IY6Q@203682|Planctomycetes	203682|Planctomycetes	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6245349_3	338969.Rfer_2368	4.491e-94	310.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2VKQS@28216|Betaproteobacteria,4AC8E@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM NADPH-dependent FMN reductase	azr	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
REGS1_k127_6245349_2	1158292.JPOE01000002_gene2576	4.535e-117	381.0	COG0580@1|root,COG0580@2|Bacteria	2|Bacteria	U	water channel activity	glpF	-	-	ko:K02440,ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8,1.A.8.1,1.A.8.2	-	-	MIP
REGS1_k127_6254014_11	580332.Slit_0445	8.277e-108	350.0	COG1643@1|root,COG2852@1|root,COG1643@2|Bacteria,COG2852@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,44VDV@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
REGS1_k127_6254014_3	395494.Galf_0098	4.616e-271	839.0	COG0579@1|root,COG0579@2|Bacteria,1MUCC@1224|Proteobacteria,2VHAA@28216|Betaproteobacteria,44VHN@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Malate:quinone oxidoreductase (Mqo)	mqo	-	1.1.5.4	ko:K00116	ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00360,R00361,R01257	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Mqo
REGS1_k127_6254014_0	580332.Slit_0450	0.0	1244.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,44VKP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_DH,Malic_M,PTA_PTB,malic
REGS1_k127_6254014_20	580332.Slit_0451	1.458e-24	104.0	2CHG9@1|root,3332K@2|Bacteria,1NCD5@1224|Proteobacteria,2VWRB@28216|Betaproteobacteria,44W1I@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6254014_7	580332.Slit_0452	9.164e-181	572.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
REGS1_k127_6254014_10	580332.Slit_0453	5.345e-135	437.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,44VHY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
REGS1_k127_6254014_13	580332.Slit_0454	2.373e-96	320.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,44VXV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
REGS1_k127_6254014_16	580332.Slit_0455	2.186e-68	241.0	2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,2VVZ5@28216|Betaproteobacteria,44VYM@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
REGS1_k127_6254014_5	580332.Slit_0458	1.082e-253	786.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,44V1C@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_6254014_17	580332.Slit_0460	6.069e-68	233.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,44VUQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
REGS1_k127_6254014_8	580332.Slit_0461	7.848e-153	486.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,44VD2@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
REGS1_k127_6254014_14	322710.Avin_01350	9.319e-94	313.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,1S22Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
REGS1_k127_6254014_18	1123487.KB892857_gene2506	7.403e-63	224.0	28IT1@1|root,2Z8S1@2|Bacteria,1PUT6@1224|Proteobacteria,2VTT1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
REGS1_k127_6254014_1	1121035.AUCH01000022_gene3191	0.0	1029.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
REGS1_k127_6254014_6	580332.Slit_0462	5.469e-191	604.0	COG0477@1|root,COG0477@2|Bacteria,1QUAG@1224|Proteobacteria,2WHA4@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08227	-	-	-	-	ko00000,ko02000	2.A.1.42	-	-	MFS_1
REGS1_k127_6254014_15	240016.ABIZ01000001_gene629	1.085e-68	250.0	COG0204@1|root,COG0204@2|Bacteria,46V7K@74201|Verrucomicrobia,2IVRK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
REGS1_k127_6254014_19	240016.ABIZ01000001_gene630	8.364e-59	215.0	COG0671@1|root,COG0671@2|Bacteria,46V6Y@74201|Verrucomicrobia,2IW2E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
REGS1_k127_6254014_2	497964.CfE428DRAFT_3364	6.304e-310	970.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,46SVA@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_6254014_9	580332.Slit_0463	2.068e-141	451.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria,44VGU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S4 RNA-binding domain	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_6254014_12	580332.Slit_0464	4.555e-99	327.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2VIBH@28216|Betaproteobacteria	28216|Betaproteobacteria	U	UPF0056 inner membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
REGS1_k127_6254014_4	580332.Slit_0466	4.889e-259	807.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,44VMW@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
REGS1_k127_6281417_5	580332.Slit_1736	1.537e-51	183.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,44VQU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
REGS1_k127_6281417_7	580332.Slit_1735	3.636e-28	115.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,44W2J@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
REGS1_k127_6281417_3	580332.Slit_1734	2.371e-61	212.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,44VWN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
REGS1_k127_6281417_1	580332.Slit_1733	1.112e-208	649.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,44VDW@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
REGS1_k127_6281417_0	580332.Slit_1731	0.0	1264.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,44V1R@713636|Nitrosomonadales	28216|Betaproteobacteria	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
REGS1_k127_6281417_4	580332.Slit_1730	5.595e-57	199.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,44VWJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_6281417_6	1123487.KB892867_gene1101	1.518e-45	167.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,2KWMH@206389|Rhodocyclales	206389|Rhodocyclales	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
REGS1_k127_6281417_2	395494.Galf_1165	8.592e-186	583.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,2VNAZ@28216|Betaproteobacteria,44W6M@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
REGS1_k127_6283394_1	697282.Mettu_2058	3.315e-284	890.0	COG2203@1|root,COG5001@1|root,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1XDYH@135618|Methylococcales	135618|Methylococcales	T	Diguanylate cyclase phosphodiesterase with PAS PAC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF
REGS1_k127_6283394_7	395494.Galf_0101	5.883e-112	369.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_6283394_4	580332.Slit_0071	5.001e-176	554.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria,44UYK@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
REGS1_k127_6283394_13	580332.Slit_0072	6.365e-35	136.0	2A8Y5@1|root,30Y1T@2|Bacteria,1PJX0@1224|Proteobacteria,2W3X5@28216|Betaproteobacteria,44WJX@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6283394_17	1479238.JQMZ01000001_gene869	3.52e-05	53.0	2AKQE@1|root,31BH5@2|Bacteria,1Q7C2@1224|Proteobacteria,2UX8A@28211|Alphaproteobacteria,43YU2@69657|Hyphomonadaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6283394_3	395494.Galf_1710	6.737e-251	785.0	COG2199@1|root,COG5000@1|root,COG2199@2|Bacteria,COG5000@2|Bacteria,1RGCV@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CHASE,CHASE8,EAL,GGDEF,HAMP,PAS,PAS_3,PAS_4,PAS_7,PAS_8,PAS_9
REGS1_k127_6283394_9	580332.Slit_0050	5.791e-93	314.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,44WHA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
REGS1_k127_6283394_6	580332.Slit_0096	2.483e-116	380.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2VQ46@28216|Betaproteobacteria,44UYG@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
REGS1_k127_6283394_0	580332.Slit_0097	0.0	1008.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,44VKU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_6283394_15	652103.Rpdx1_1939	2.074e-11	73.0	28VT5@1|root,33M73@2|Bacteria,1NKJD@1224|Proteobacteria,2UXQX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6283394_10	614083.AWQR01000038_gene1432	3.405e-50	183.0	2DHFK@1|root,32U96@2|Bacteria,1N6CG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6283394_8	580332.Slit_0099	1.469e-98	323.0	COG3545@1|root,COG3545@2|Bacteria,1RDB7@1224|Proteobacteria,2VQ1M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	esterase of the alpha beta hydrolase fold	-	-	-	ko:K07002	-	-	-	-	ko00000	-	-	-	Ser_hydrolase
REGS1_k127_6283394_2	580332.Slit_0100	2.123e-252	782.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,2VHD9@28216|Betaproteobacteria,44V1Q@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Glutamate-cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
REGS1_k127_6283394_5	580332.Slit_0101	9.62e-164	533.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,44VGN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	rnfF	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
REGS1_k127_6283394_11	395494.Galf_0111	2.204e-49	180.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,44W0H@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	manX	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
REGS1_k127_6283394_12	1485544.JQKP01000002_gene1563	1.616e-40	151.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,44VZQ@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PTS HPr component phosphorylation site	ptsH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
REGS1_k127_6368054_2	402777.KB235903_gene1652	9.188e-60	227.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1G4ED@1117|Cyanobacteria,1HA0Q@1150|Oscillatoriales	1117|Cyanobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Guanylate_cyc
REGS1_k127_6368054_1	580332.Slit_0289	1.405e-117	382.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,44VQC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
REGS1_k127_6368054_0	580332.Slit_0290	1.413e-203	638.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,44V5S@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiF	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
REGS1_k127_6413827_12	580332.Slit_1656	5.249e-39	146.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,2VTN7@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
REGS1_k127_6413827_2	580332.Slit_1655	5.907e-221	691.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,44W4C@713636|Nitrosomonadales	28216|Betaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
REGS1_k127_6413827_1	1288494.EBAPG3_25040	9.117e-293	914.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,2VK1A@28216|Betaproteobacteria,371Y7@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6413827_0	580332.Slit_1654	2.755e-297	917.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,44V57@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
REGS1_k127_6413827_11	1485544.JQKP01000011_gene722	1.134e-59	207.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,44VU5@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
REGS1_k127_6413827_13	395494.Galf_0727	2.232e-37	145.0	2D4HK@1|root,32TH5@2|Bacteria,1N3UQ@1224|Proteobacteria,2W3Y0@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6413827_14	631362.Thi970DRAFT_03964	1.546e-29	126.0	COG1396@1|root,COG1396@2|Bacteria,1N3RQ@1224|Proteobacteria,1S3WE@1236|Gammaproteobacteria,1X115@135613|Chromatiales	135613|Chromatiales	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	-	-	-	-	-	-	-	-	-	MqsA_antitoxin
REGS1_k127_6413827_9	580332.Slit_2676	1.315e-81	276.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,44VZ1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Smr domain	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
REGS1_k127_6413827_3	1485544.JQKP01000005_gene378	1.298e-186	586.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,44VC9@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_6413827_5	580332.Slit_2674	3.455e-140	451.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2VJGZ@28216|Betaproteobacteria,44VFF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transglycosylase SLT domain	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
REGS1_k127_6413827_10	580332.Slit_2673	1.298e-64	224.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,44VY3@713636|Nitrosomonadales	28216|Betaproteobacteria	M	NlpC/P60 family	-	-	-	ko:K19303	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
REGS1_k127_6413827_6	580332.Slit_0324	1.911e-134	432.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,44V2Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
REGS1_k127_6413827_7	580332.Slit_0325	1.495e-113	370.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,44VA5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_6413827_8	580332.Slit_0326	1.331e-104	349.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,44VQ0@713636|Nitrosomonadales	28216|Betaproteobacteria	DM	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
REGS1_k127_6413827_4	580332.Slit_0327	3.294e-146	466.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,44VI2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_6413827_15	666681.M301_0436	6.685e-14	83.0	29TFP@1|root,30ENV@2|Bacteria,1RG86@1224|Proteobacteria,2VS6R@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6427801_6	580332.Slit_2707	1.059e-24	106.0	COG0664@1|root,COG0664@2|Bacteria,1NBRS@1224|Proteobacteria,2WCFJ@28216|Betaproteobacteria,44VZA@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_6427801_1	580332.Slit_1039	1.138e-163	521.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,44UZ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
REGS1_k127_6427801_4	580332.Slit_1040	5.591e-56	197.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria	28216|Betaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
REGS1_k127_6427801_5	580332.Slit_1041	2.037e-29	128.0	COG3474@1|root,COG3474@2|Bacteria,1NIH9@1224|Proteobacteria,2WHPP@28216|Betaproteobacteria,44W35@713636|Nitrosomonadales	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
REGS1_k127_6427801_0	580332.Slit_1042	6.666e-210	659.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,44VFZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
REGS1_k127_6427801_3	580332.Slit_1043	1.747e-101	342.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,44VDX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
REGS1_k127_6427801_2	1485544.JQKP01000018_gene571	3.284e-116	383.0	COG1819@1|root,COG1819@2|Bacteria,1MVJM@1224|Proteobacteria,2VME8@28216|Betaproteobacteria,44V3H@713636|Nitrosomonadales	28216|Betaproteobacteria	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6457885_3	580332.Slit_2848	2.513e-24	109.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,44VZ0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
REGS1_k127_6457885_0	1485544.JQKP01000002_gene1453	0.0	1423.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,44V3Z@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
REGS1_k127_6457885_2	395494.Galf_2873	1.079e-175	553.0	COG3954@1|root,COG3954@2|Bacteria,1MWN9@1224|Proteobacteria,2VHZD@28216|Betaproteobacteria,44VEV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Phosphoribulokinase / Uridine kinase family	cbbP	-	2.7.1.19	ko:K00855	ko00710,ko01100,ko01120,ko01200,map00710,map01100,map01120,map01200	M00165,M00166	R01523	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PRK
REGS1_k127_6457885_1	580332.Slit_2844	9.549e-215	671.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,44VHM@713636|Nitrosomonadales	28216|Betaproteobacteria	L	UvrD-like helicase C-terminal domain	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_6536370_0	580332.Slit_1474	0.0	1043.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VM9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
REGS1_k127_6536370_1	580332.Slit_1475	4.279e-174	548.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,44V13@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_6536370_2	580332.Slit_1476	5.195e-111	363.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VQBC@28216|Betaproteobacteria,44VVE@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM class II aldolase adducin family protein	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
REGS1_k127_6536370_3	580332.Slit_1477	2.518e-101	332.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2VI7G@28216|Betaproteobacteria,44VQ2@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
REGS1_k127_6536370_4	1538295.JY96_09755	4.298e-61	237.0	28KDG@1|root,2Z9ZZ@2|Bacteria,1R86C@1224|Proteobacteria,2W193@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6558531_0	580332.Slit_0965	0.0	1098.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,44VIS@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM ATP-dependent Clp protease, ATP-binding subunit clpA	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_6558531_2	1280001.BAOA01000135_gene1922	6.917e-52	187.0	2CFS9@1|root,32Y2C@2|Bacteria,1NNYX@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6558531_1	580332.Slit_0964	1.935e-95	315.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,44VQH@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_6629651_0	580332.Slit_2861	3.247e-249	773.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria,44V7J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
REGS1_k127_6629651_2	580332.Slit_2860	1.471e-69	237.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,44VU2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
REGS1_k127_6629651_1	1485544.JQKP01000002_gene1535	3.03e-212	665.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,44VKF@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
REGS1_k127_6653254_2	580332.Slit_2262	2.041e-188	600.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,44V6H@713636|Nitrosomonadales	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
REGS1_k127_6653254_8	1005048.CFU_2947	7.851e-97	332.0	2AEFS@1|root,314AU@2|Bacteria,1RKTV@1224|Proteobacteria,2VSSU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6653254_5	1005048.CFU_2946	5.663e-117	384.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,2W992@28216|Betaproteobacteria,476PH@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_6653254_6	1485544.JQKP01000001_gene1153	6.628e-110	358.0	COG1392@1|root,COG1392@2|Bacteria,1NDTG@1224|Proteobacteria,2VJ5F@28216|Betaproteobacteria,44W8U@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
REGS1_k127_6653254_1	1485544.JQKP01000001_gene1154	4.31e-194	608.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,2VI71@28216|Betaproteobacteria,44W3P@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
REGS1_k127_6653254_3	580332.Slit_2259	1.019e-148	473.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,44V7M@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
REGS1_k127_6653254_7	395494.Galf_0641	1.132e-108	358.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,44VDH@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_6653254_4	580332.Slit_2257	1.6e-145	462.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,44VK5@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
REGS1_k127_6653254_10	580332.Slit_2256	5.828e-66	228.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,44VWG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
REGS1_k127_6653254_0	580332.Slit_2255	7.063e-239	741.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,44V1D@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
REGS1_k127_6653254_9	580332.Slit_2254	1.01e-81	272.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,44VSJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
REGS1_k127_6655185_2	580332.Slit_2828	3.343e-90	299.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJGY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_9,TarH
REGS1_k127_6655185_4	580332.Slit_2827	2.419e-72	245.0	COG0745@1|root,COG0745@2|Bacteria,1RD6H@1224|Proteobacteria,2W433@28216|Betaproteobacteria,44WKS@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_6655185_1	580332.Slit_2826	1.51e-189	605.0	COG0745@1|root,COG2202@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHVM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	PAS,Response_reg
REGS1_k127_6655185_3	425104.Ssed_3748	6.865e-88	297.0	2B14P@1|root,31TII@2|Bacteria,1QR95@1224|Proteobacteria,1SN3G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
REGS1_k127_6655185_5	425104.Ssed_3748	1.181e-25	107.0	2B14P@1|root,31TII@2|Bacteria,1QR95@1224|Proteobacteria,1SN3G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
REGS1_k127_6655185_0	580332.Slit_2241	0.0	1432.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,44WDB@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
REGS1_k127_67202_0	580332.Slit_2775	3.751e-100	336.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2VUQP@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_67202_2	580332.Slit_2776	6.617e-34	137.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,2VVRU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
REGS1_k127_6722098_19	261292.Nit79A3_0089	6.734e-50	183.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,2VU39@28216|Betaproteobacteria,37493@32003|Nitrosomonadales	28216|Betaproteobacteria	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
REGS1_k127_6722098_16	580332.Slit_1397	1.576e-75	260.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,44VXR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
REGS1_k127_6722098_3	580332.Slit_1396	0.0	1099.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,44UYC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
REGS1_k127_6722098_7	580332.Slit_1787	5.108e-232	721.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,44VPA@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_6722098_8	580332.Slit_1789	2.546e-229	741.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	sprD	-	-	-	-	-	-	-	-	-	-	-	DivIVA,PorP_SprF
REGS1_k127_6722098_4	1163617.SCD_n01679	4.48e-309	954.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,2VHBY@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Asparagine synthase	-	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
REGS1_k127_6722098_10	580332.Slit_1790	4.829e-155	499.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,44V8W@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmI	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
REGS1_k127_6722098_18	1485544.JQKP01000007_gene1987	4.54e-61	213.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,44VXQ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Cytochrome C biogenesis protein	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
REGS1_k127_6722098_15	395494.Galf_1767	1.709e-84	286.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,44VSS@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
REGS1_k127_6722098_2	580332.Slit_1793	0.0	1165.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,44VEM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
REGS1_k127_6722098_17	580332.Slit_1794	5.691e-71	243.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,44VV9@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
REGS1_k127_6722098_21	580332.Slit_1795	1.832e-14	82.0	COG3114@1|root,COG3114@2|Bacteria	2|Bacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735	CcmD
REGS1_k127_6722098_11	580332.Slit_1796	7.747e-140	448.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,44VN4@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
REGS1_k127_6722098_13	580332.Slit_1797	1.915e-116	379.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,44VAM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
REGS1_k127_6722098_14	580332.Slit_1798	6.054e-95	316.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,44V0F@713636|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
REGS1_k127_6722098_6	580332.Slit_1800	2.867e-244	769.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,44V8Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SurA N-terminal domain	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_6722098_22	1454202.PPBDW_120198___1	5.444e-10	63.0	2DP07@1|root,3300A@2|Bacteria,1N90I@1224|Proteobacteria,1SFUI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6722098_0	580332.Slit_1802	0.0	1461.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,44VGG@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_6722098_5	580332.Slit_1803	2.492e-252	781.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,44V8T@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
REGS1_k127_6722098_12	580332.Slit_1804	7.589e-119	383.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,44VMK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
REGS1_k127_6722098_9	580332.Slit_1805	2.082e-220	689.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,44V5B@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
REGS1_k127_6722098_1	580332.Slit_1806	0.0	1375.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,44WD2@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_6722098_20	1123368.AUIS01000009_gene2509	1.513e-26	111.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,1RQ3P@1236|Gammaproteobacteria,2NCP7@225057|Acidithiobacillales	225057|Acidithiobacillales	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
REGS1_k127_6723_4	580332.Slit_2064	3.357e-127	407.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,44V48@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_6723_2	580332.Slit_2065	1.173e-202	635.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,44UYW@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Chorismate mutase type II	pheA	-	4.2.1.51,4.2.1.91,5.4.99.5	ko:K01713,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
REGS1_k127_6723_3	335283.Neut_1571	2.574e-155	499.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,2VIHG@28216|Betaproteobacteria,371V7@32003|Nitrosomonadales	28216|Betaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
REGS1_k127_6723_1	580332.Slit_2067	3.667e-226	703.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,44VKB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
REGS1_k127_6723_0	580332.Slit_2068	0.0	1566.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,44VGS@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
REGS1_k127_6735971_6	1485544.JQKP01000012_gene2152	1.547e-113	372.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,44V6X@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Amidohydrolase family	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
REGS1_k127_6735971_4	580332.Slit_2932	7.373e-191	597.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,44VME@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_6735971_10	580332.Slit_2933	1.879e-73	250.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,44VTU@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
REGS1_k127_6735971_8	580332.Slit_2935	3.95e-105	342.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,44VSQ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
REGS1_k127_6735971_0	580332.Slit_2936	0.0	1936.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,44W8H@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
REGS1_k127_6735971_3	580332.Slit_2937	3.3e-194	627.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,44W5A@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	pilJ	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
REGS1_k127_6735971_13	580332.Slit_2938	7.3e-57	203.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,44WGG@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
REGS1_k127_6735971_14	1121035.AUCH01000003_gene1375	7.654e-45	165.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,2KWTI@206389|Rhodocyclales	206389|Rhodocyclales	T	response regulator receiver	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_6735971_11	580332.Slit_2940	2.276e-65	225.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria,44WGJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	cheY-homologous receiver domain	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_6735971_1	580332.Slit_2941	1.033e-270	838.0	COG0168@1|root,COG0168@2|Bacteria,1MUIJ@1224|Proteobacteria,2VH82@28216|Betaproteobacteria,44W7S@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
REGS1_k127_6735971_2	580332.Slit_2942	1.644e-249	779.0	COG0569@1|root,COG0569@2|Bacteria,1MW8R@1224|Proteobacteria,2VIH1@28216|Betaproteobacteria,44W83@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM TrkA-N domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
REGS1_k127_6735971_5	580332.Slit_2943	4.498e-114	370.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria,44VDM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_6735971_7	580332.Slit_2944	3.341e-106	349.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,44VQY@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
REGS1_k127_6735971_15	580332.Slit_2947	1.793e-26	122.0	COG1942@1|root,COG1942@2|Bacteria,1NC22@1224|Proteobacteria,2VWHU@28216|Betaproteobacteria,44WJF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
REGS1_k127_6735971_12	460265.Mnod_2480	8.566e-62	233.0	COG0457@1|root,COG4249@1|root,COG0457@2|Bacteria,COG4249@2|Bacteria,1RKBA@1224|Proteobacteria,2TRAV@28211|Alphaproteobacteria,1JXI4@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
REGS1_k127_6735971_9	580332.Slit_2948	1.071e-98	326.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,44V7Q@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
REGS1_k127_6737056_3	580332.Slit_1186	2.972e-23	99.0	COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,2VTBD@28216|Betaproteobacteria,44WHB@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6737056_2	580332.Slit_1197	6.139e-103	339.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,44VA5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_6737056_1	243233.MCA2787	1.421e-146	476.0	COG0695@1|root,COG0695@2|Bacteria,1QVSK@1224|Proteobacteria,1T3G3@1236|Gammaproteobacteria,1XDZF@135618|Methylococcales	135618|Methylococcales	O	PFAM glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
REGS1_k127_6737056_0	580332.Slit_1198	3.992e-273	850.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,44W68@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.9	ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
REGS1_k127_6775323_0	580332.Slit_2108	1.18e-316	971.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,44VHT@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
REGS1_k127_6775323_3	580332.Slit_2109	1.753e-71	244.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,44W0T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
REGS1_k127_6775323_4	580332.Slit_2110	6.351e-57	205.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,44VYQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sporulation related domain	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
REGS1_k127_6775323_1	580332.Slit_2111	7.04e-255	790.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,44V34@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Mur ligase middle domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
REGS1_k127_6775323_5	1226322.HMPREF1545_02190	6.124e-16	79.0	2F2Z4@1|root,33VUG@2|Bacteria,1VVGK@1239|Firmicutes,251AI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6775323_2	580332.Slit_2113	4.943e-166	524.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,44VH8@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
REGS1_k127_685665_0	580332.Slit_1835	0.0	1530.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,44VD6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	2-oxoglutarate dehydrogenase N-terminus	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
REGS1_k127_685665_1	580332.Slit_1834	1.599e-124	405.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,44VDJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
REGS1_k127_68825_5	580332.Slit_2366	7.138e-60	211.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,44VUP@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
REGS1_k127_68825_1	395494.Galf_0463	4.327e-188	597.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,44UZ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_68825_0	580332.Slit_2368	8.93e-222	694.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,44VBT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_68825_2	580332.Slit_2369	1.478e-168	533.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,44V41@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
REGS1_k127_68825_3	580332.Slit_2370	2.196e-131	420.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,44VG7@713636|Nitrosomonadales	28216|Betaproteobacteria	D	TIGRFAM cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
REGS1_k127_68825_4	580332.Slit_2371	6.849e-86	287.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,44VHS@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
REGS1_k127_6890810_15	395494.Galf_0766	1.681e-49	185.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2VT7Q@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	nsrR	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
REGS1_k127_6890810_19	1121094.KB894644_gene2083	3.511e-36	145.0	COG2846@1|root,COG2846@2|Bacteria,4NE9M@976|Bacteroidetes,2FQ3S@200643|Bacteroidia,4APKF@815|Bacteroidaceae	976|Bacteroidetes	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	ric	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
REGS1_k127_6890810_5	395494.Galf_2482	7.728e-84	281.0	COG1622@1|root,COG1622@2|Bacteria,1RHZD@1224|Proteobacteria,2VZ0B@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase subunit II, periplasmic domain	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2
REGS1_k127_6890810_0	395494.Galf_2481	2.915e-251	781.0	COG0843@1|root,COG0843@2|Bacteria,1PVEV@1224|Proteobacteria,2VK5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome C oxidase subunit I	coxA2	-	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
REGS1_k127_6890810_6	395494.Galf_2480	1.266e-82	278.0	COG1999@1|root,COG1999@2|Bacteria,1N17T@1224|Proteobacteria,2VQFQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SCO1/SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
REGS1_k127_6890810_13	395494.Galf_2479	2.557e-65	233.0	2CFGU@1|root,32SXK@2|Bacteria,1MZBH@1224|Proteobacteria,2VRJH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6890810_11	1485544.JQKP01000001_gene1204	5.111e-69	241.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria,44W1J@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM HPP family protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
REGS1_k127_6890810_18	580332.Slit_2246	2.486e-45	166.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,44WIJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Invasion gene expression up-regulator, SirB	sirB	-	-	-	-	-	-	-	-	-	-	-	SirB
REGS1_k127_6890810_14	1485544.JQKP01000003_gene98	1.949e-53	197.0	COG3945@1|root,COG3945@2|Bacteria,1N0BD@1224|Proteobacteria,2VUY4@28216|Betaproteobacteria,44WHW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
REGS1_k127_6890810_1	580332.Slit_2244	5.892e-204	643.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VIGJ@28216|Betaproteobacteria,44V7G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
REGS1_k127_6890810_10	580332.Slit_2245	1.77e-71	246.0	COG3038@1|root,COG3038@2|Bacteria,1PIVP@1224|Proteobacteria,2W7F3@28216|Betaproteobacteria,44VYF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_6890810_21	1163617.SCD_n01783	1.03e-32	131.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6890810_8	228410.NE0717	5.278e-80	271.0	COG1278@1|root,COG3326@1|root,COG1278@2|Bacteria,COG3326@2|Bacteria,1N6YM@1224|Proteobacteria,2VQXP@28216|Betaproteobacteria	28216|Betaproteobacteria	K	DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	CSD,DUF1294
REGS1_k127_6890810_23	666685.R2APBS1_3901	1.553e-31	130.0	2FHZU@1|root,349SS@2|Bacteria,1P0AP@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6890810_2	580332.Slit_0830	1.765e-202	642.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria,44WDH@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM UMUC domain protein DNA-repair protein	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
REGS1_k127_6890810_7	580332.Slit_0831	3.925e-80	269.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2VU86@28216|Betaproteobacteria,44WF8@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Peptidase S24 S26A S26B, conserved region	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
REGS1_k127_6890810_4	580332.Slit_2300	2.474e-103	339.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VS2C@28216|Betaproteobacteria,44VHF@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM Peptidase S24 S26A S26B, conserved region	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
REGS1_k127_6890810_3	1236959.BAMT01000001_gene1684	1.531e-150	481.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VIY2@28216|Betaproteobacteria,2KPA2@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
REGS1_k127_6890810_20	1101195.Meth11DRAFT_1647	4.593e-36	141.0	COG2246@1|root,COG2246@2|Bacteria,1N6WN@1224|Proteobacteria,2VW0C@28216|Betaproteobacteria,2KN76@206350|Nitrosomonadales	206350|Nitrosomonadales	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
REGS1_k127_6890810_12	1101195.Meth11DRAFT_1646	1.032e-68	246.0	COG3394@1|root,COG3394@2|Bacteria,1MX3P@1224|Proteobacteria,2VSK0@28216|Betaproteobacteria,2KMMB@206350|Nitrosomonadales	206350|Nitrosomonadales	G	YdjC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YdjC
REGS1_k127_6890810_17	580332.Slit_2364	8.376e-46	166.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,44W12@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
REGS1_k127_6890810_9	580332.Slit_2365	2.162e-79	267.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,44VPS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_6890810_22	580332.Slit_2366	3.624e-32	127.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,44VUP@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
REGS1_k127_6899975_1	580332.Slit_1751	1.104e-90	301.0	COG2755@1|root,COG2755@2|Bacteria,1RCXZ@1224|Proteobacteria,2VRIQ@28216|Betaproteobacteria,44VVJ@713636|Nitrosomonadales	28216|Betaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	tesA	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL_2
REGS1_k127_6899975_0	580332.Slit_1752	0.0	1126.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
REGS1_k127_6909480_1	580332.Slit_1759	0.0	1172.0	COG0729@1|root,COG0729@2|Bacteria,1QVQI@1224|Proteobacteria,2W0WR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6909480_0	580332.Slit_1758	0.0	1210.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,44V30@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
REGS1_k127_6909480_2	580332.Slit_1757	5.367e-172	543.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,44VCM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_6919951_1	1288494.EBAPG3_8880	1.94e-228	718.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria,3724W@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
REGS1_k127_6919951_5	580332.Slit_2870	9.475e-46	166.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
REGS1_k127_6919951_6	580332.Slit_2869	1.645e-35	138.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VV0X@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_6919951_3	1123393.KB891316_gene1217	1.26e-137	448.0	28KSV@1|root,2ZAA5@2|Bacteria,1R8PW@1224|Proteobacteria,2VMYF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6919951_4	1288494.EBAPG3_2120	1.338e-49	181.0	COG1132@1|root,COG1132@2|Bacteria,1RDIA@1224|Proteobacteria,2VR6J@28216|Betaproteobacteria,3737R@32003|Nitrosomonadales	28216|Betaproteobacteria	V	Domain of unknown function (DUF1854)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1854
REGS1_k127_6919951_0	395494.Galf_1606	0.0	1138.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,44W70@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_6919951_2	395494.Galf_1605	1.1e-224	702.0	COG1181@1|root,COG1181@2|Bacteria,1QWAW@1224|Proteobacteria,2VITI@28216|Betaproteobacteria,44W75@713636|Nitrosomonadales	28216|Betaproteobacteria	M	RimK-like ATP-grasp domain	cphA2	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	CPSase_L_D2,Mur_ligase_C,Mur_ligase_M,RimK
REGS1_k127_7017497_4	1485544.JQKP01000017_gene615	2.241e-142	456.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,44V4R@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_7017497_5	580332.Slit_0636	2.288e-122	396.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,44V8N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	NIF3 (NGG1p interacting factor 3)	ybgI	-	-	-	-	-	-	-	-	-	-	-	NIF3
REGS1_k127_7017497_9	1485544.JQKP01000017_gene617	1.07e-57	207.0	2AG1B@1|root,3165E@2|Bacteria,1PWWQ@1224|Proteobacteria,2WCF3@28216|Betaproteobacteria,44VY6@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7017497_6	580332.Slit_0640	1.717e-101	335.0	COG2010@1|root,COG2010@2|Bacteria,1P88Q@1224|Proteobacteria,2W4CG@28216|Betaproteobacteria,44VXH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7017497_0	580332.Slit_0641	0.0	1072.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44V4I@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
REGS1_k127_7017497_3	395494.Galf_0450	2.666e-160	507.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44V6V@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
REGS1_k127_7017497_1	580332.Slit_0643	6.748e-281	866.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,2VWU7@28216|Betaproteobacteria,44VHA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
REGS1_k127_7017497_7	1485544.JQKP01000017_gene623	2.988e-95	314.0	2DSXF@1|root,33HTI@2|Bacteria,1NHAS@1224|Proteobacteria,2WCC6@28216|Betaproteobacteria,44VSE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
REGS1_k127_7017497_8	580332.Slit_0645	2.957e-73	250.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria,2WCCQ@28216|Betaproteobacteria,44VT7@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
REGS1_k127_7017497_2	580332.Slit_0646	1.1e-164	523.0	COG5557@1|root,COG5557@2|Bacteria,1QZY1@1224|Proteobacteria,2W53W@28216|Betaproteobacteria,44V2N@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7043812_1	580332.Slit_2026	1.116e-140	453.0	COG0063@1|root,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,44VJ1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
REGS1_k127_7043812_5	580332.Slit_2027	4.009e-71	244.0	2BWTE@1|root,32YDB@2|Bacteria,1N0HE@1224|Proteobacteria,2VYW4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2937
REGS1_k127_7043812_4	395494.Galf_0522	3.843e-119	388.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,44V2F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Spermine synthase	speE1	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_7043812_12	580332.Slit_2029	2.414e-15	80.0	2ENVQ@1|root,33GGS@2|Bacteria,1NGVT@1224|Proteobacteria,2VY6X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
REGS1_k127_7043812_9	580332.Slit_2030	7.649e-49	176.0	COG1993@1|root,COG1993@2|Bacteria,1RH30@1224|Proteobacteria,2WFX5@28216|Betaproteobacteria,44W30@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1993	-	-	-	-	-	-	-	-	-	-	-	-	DUF190
REGS1_k127_7043812_6	1485544.JQKP01000019_gene24	2.982e-70	239.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria,44VTA@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
REGS1_k127_7043812_8	580332.Slit_2032	2.094e-55	194.0	COG0727@1|root,COG0727@2|Bacteria,1N027@1224|Proteobacteria,2VV5B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
REGS1_k127_7043812_0	580332.Slit_2033	3.849e-269	831.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,44V4G@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_7043812_2	741091.Rahaq_2868	7.829e-135	434.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,1RNS2@1236|Gammaproteobacteria,3FHF2@34037|Rahnella	1236|Gammaproteobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
REGS1_k127_7043812_3	580332.Slit_2034	9.987e-126	407.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria,44UZT@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
REGS1_k127_7043812_7	857087.Metme_0429	2.455e-64	223.0	COG2337@1|root,COG2337@2|Bacteria,1PVJ9@1224|Proteobacteria,1TM47@1236|Gammaproteobacteria,1XGTH@135618|Methylococcales	135618|Methylococcales	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
REGS1_k127_7043812_11	857087.Metme_0430	1.485e-32	127.0	COG2336@1|root,COG2336@2|Bacteria,1N7DX@1224|Proteobacteria,1STBB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Antidote-toxin recognition MazE, bacterial antitoxin	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
REGS1_k127_7043812_10	1454004.AW11_01193	8.259e-39	162.0	COG1864@1|root,COG2931@1|root,COG3179@1|root,COG3209@1|root,COG3391@1|root,COG1864@2|Bacteria,COG2931@2|Bacteria,COG3179@2|Bacteria,COG3209@2|Bacteria,COG3391@2|Bacteria,1RC1P@1224|Proteobacteria,2VUZC@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Chitinase class I	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Glyco_hydro_19
REGS1_k127_7043812_13	1323663.AROI01000015_gene603	5.119e-09	57.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,1RSCP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_7069199_0	580332.Slit_1982	2.518e-186	591.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,44VGE@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_7069199_1	580332.Slit_1983	4.394e-181	569.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,44VB3@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_7069199_2	580332.Slit_1984	3.508e-115	374.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
REGS1_k127_7069199_4	580332.Slit_1985	1.485e-86	290.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	DSBA Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
REGS1_k127_7069199_3	335283.Neut_0487	2.732e-90	302.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,372CA@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
REGS1_k127_7084292_6	580332.Slit_1320	1.097e-129	416.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2VHXT@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
REGS1_k127_7084292_12	1123368.AUIS01000005_gene353	5.43e-13	70.0	28XT8@1|root,2ZJPP@2|Bacteria,1P53A@1224|Proteobacteria,1SVUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF3330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3330
REGS1_k127_7084292_1	580332.Slit_2137	5.143e-201	631.0	COG0741@1|root,COG0741@2|Bacteria,1MW2T@1224|Proteobacteria,2VZZ3@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Domain of unknown function (DUF3393)	-	-	-	ko:K08306	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT
REGS1_k127_7084292_0	580332.Slit_2138	0.0	1094.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,44V96@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter C-terminal domain	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
REGS1_k127_7084292_9	395494.Galf_2043	6.342e-53	190.0	2A86F@1|root,30X7C@2|Bacteria,1PJ0W@1224|Proteobacteria,2W7KJ@28216|Betaproteobacteria,44W04@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7084292_8	580332.Slit_2140	5.664e-94	310.0	COG1225@1|root,COG1225@2|Bacteria,1RH4P@1224|Proteobacteria,2VT1P@28216|Betaproteobacteria,44WFG@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_7084292_5	580332.Slit_2147	6.926e-137	441.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,2VI8F@28216|Betaproteobacteria	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_7084292_11	1343740.M271_13980	3.387e-32	128.0	COG1917@1|root,COG1917@2|Bacteria,2IKKG@201174|Actinobacteria	201174|Actinobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
REGS1_k127_7084292_10	292415.Tbd_2410	3.209e-44	166.0	COG3791@1|root,COG3791@2|Bacteria,1N031@1224|Proteobacteria,2VUC4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Glutathione-dependent formaldehyde-activating	-	-	-	-	-	-	-	-	-	-	-	-	GFA
REGS1_k127_7084292_2	1304883.KI912532_gene1874	4.054e-172	550.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1R53C@1224|Proteobacteria,2VNCZ@28216|Betaproteobacteria,2KW0J@206389|Rhodocyclales	206389|Rhodocyclales	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
REGS1_k127_7084292_3	395494.Galf_1704	2.061e-169	537.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,44VM5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
REGS1_k127_7084292_4	395494.Galf_1705	1.527e-151	489.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,44VMP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Rhodanese Homology Domain	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
REGS1_k127_7084292_7	580332.Slit_2142	4.999e-124	401.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria,44VAB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
REGS1_k127_7139231_22	1163617.SCD_n01011	6.732e-16	80.0	2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,2VX4M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
REGS1_k127_7139231_6	580332.Slit_1559	7.448e-129	419.0	COG2199@1|root,COG3706@2|Bacteria,1REIE@1224|Proteobacteria,2W3W6@28216|Betaproteobacteria,44WHE@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,cNMP_binding
REGS1_k127_7139231_13	1121921.KB898706_gene3386	2.227e-60	227.0	COG0457@1|root,COG0457@2|Bacteria	1121921.KB898706_gene3386|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7139231_20	999541.bgla_1g11010	6.427e-22	98.0	2A8EN@1|root,30XGG@2|Bacteria,1PJBR@1224|Proteobacteria,2W7VQ@28216|Betaproteobacteria,1KF8B@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2188)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2188
REGS1_k127_7139231_19	395494.Galf_1208	5.722e-33	132.0	COG0484@1|root,COG0484@2|Bacteria,1N2YE@1224|Proteobacteria,2VU46@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
REGS1_k127_7139231_18	1198452.Jab_1c16720	1.985e-40	155.0	2A7IB@1|root,30WG3@2|Bacteria,1PI53@1224|Proteobacteria,2W6R3@28216|Betaproteobacteria,47752@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7139231_16	1144342.PMI40_04776	3.021e-54	197.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria,473E2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
REGS1_k127_7139231_7	580332.Slit_2135	3.815e-111	366.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
REGS1_k127_7139231_11	580332.Slit_2275	5.833e-77	260.0	COG2199@1|root,COG2199@2|Bacteria,1N5XD@1224|Proteobacteria,2VVIH@28216|Betaproteobacteria	28216|Betaproteobacteria	T	diguanylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_7139231_4	580332.Slit_1573	8.308e-173	544.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria,44W51@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SMART band 7 protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
REGS1_k127_7139231_12	580332.Slit_1574	7.492e-62	216.0	COG1585@1|root,COG1585@2|Bacteria,1PT3V@1224|Proteobacteria,2WADK@28216|Betaproteobacteria,44W42@713636|Nitrosomonadales	28216|Betaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
REGS1_k127_7139231_14	1485544.JQKP01000019_gene8	1.026e-59	231.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_7139231_3	580332.Slit_1540	1.03e-173	548.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria,44W72@713636|Nitrosomonadales	28216|Betaproteobacteria	BQ	PFAM histone deacetylase superfamily	hda	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
REGS1_k127_7139231_1	580332.Slit_1541	0.0	1575.0	COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria,44WDS@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM CoA-binding domain protein	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
REGS1_k127_7139231_17	640081.Dsui_3335	9.976e-44	171.0	COG2204@1|root,COG2204@2|Bacteria,1QXKB@1224|Proteobacteria,2WI0Q@28216|Betaproteobacteria,2KZY5@206389|Rhodocyclales	28216|Betaproteobacteria	T	Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_7139231_2	395494.Galf_0835	2.955e-207	656.0	COG2703@1|root,COG4191@1|root,COG2703@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,44WDU@713636|Nitrosomonadales	28216|Betaproteobacteria	PT	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Hemerythrin,HisKA,PAS_4
REGS1_k127_7139231_0	395494.Galf_0833	0.0	1592.0	COG2202@1|root,COG2203@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W4W@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
REGS1_k127_7139231_15	580332.Slit_2419	3.254e-57	200.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,44W8A@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM AIR synthase related protein domain protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
REGS1_k127_7144304_6	580332.Slit_0976	2.41e-59	209.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,44VVC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	NUDIX domain	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
REGS1_k127_7144304_7	580332.Slit_0975	3.527e-48	179.0	COG2732@1|root,COG2732@2|Bacteria,1PCTM@1224|Proteobacteria,2WA4A@28216|Betaproteobacteria,44WMH@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
REGS1_k127_7144304_5	580332.Slit_0974	9.335e-60	210.0	COG4290@1|root,COG4290@2|Bacteria,1MZEZ@1224|Proteobacteria,2VTZ7@28216|Betaproteobacteria,44W1Y@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM guanine-specific ribonuclease N1 and T1	rnaSA	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
REGS1_k127_7144304_1	580332.Slit_0973	0.0	1144.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,44V9U@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
REGS1_k127_7144304_3	580332.Slit_0972	7.588e-108	353.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,44VQ6@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
REGS1_k127_7144304_10	395494.Galf_2466	3.328e-29	118.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,44W49@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
REGS1_k127_7144304_4	580332.Slit_0969	1.718e-91	303.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2VQAQ@28216|Betaproteobacteria,44UYV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
REGS1_k127_7144304_0	395494.Galf_2246	0.0	1223.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,44VC6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	icd_2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
REGS1_k127_7144304_9	580332.Slit_0967	7.623e-37	139.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,44VZU@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_7144304_8	580332.Slit_0966	3.212e-46	171.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,44VZ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
REGS1_k127_7144304_2	580332.Slit_0965	1.522e-122	394.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,44VIS@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM ATP-dependent Clp protease, ATP-binding subunit clpA	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_7160083_3	580332.Slit_2350	1.452e-10	61.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VDC@713636|Nitrosomonadales	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
REGS1_k127_7160083_0	748247.AZKH_1543	2.915e-193	609.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VHE6@28216|Betaproteobacteria,2KVS3@206389|Rhodocyclales	206389|Rhodocyclales	EK	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
REGS1_k127_7160083_2	748247.AZKH_1544	2.697e-65	226.0	COG1846@1|root,COG1846@2|Bacteria,1RIX7@1224|Proteobacteria,2VUFV@28216|Betaproteobacteria,2KX57@206389|Rhodocyclales	206389|Rhodocyclales	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
REGS1_k127_7160083_1	580332.Slit_0997	1.263e-73	249.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,44VD8@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
REGS1_k127_7193005_0	1485544.JQKP01000002_gene1351	1.87e-223	699.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VDC@713636|Nitrosomonadales	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
REGS1_k127_7193005_5	580332.Slit_2349	1.136e-98	324.0	COG3310@1|root,COG3310@2|Bacteria,1RDE0@1224|Proteobacteria,2VQ9D@28216|Betaproteobacteria,44WFP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1415)	-	-	-	ko:K09941	-	-	-	-	ko00000	-	-	-	DUF1415
REGS1_k127_7193005_10	316056.RPC_1461	2.03e-13	76.0	COG5346@1|root,COG5346@2|Bacteria,1N9PG@1224|Proteobacteria,2UIX7@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Predicted membrane protein (DUF2335)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2335
REGS1_k127_7193005_2	580332.Slit_2348	1.756e-198	619.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,44V37@713636|Nitrosomonadales	28216|Betaproteobacteria	H	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
REGS1_k127_7193005_7	580332.Slit_2346	4.782e-60	209.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria,44VZG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
REGS1_k127_7193005_6	1163617.SCD_n01089	1.011e-84	286.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria	1224|Proteobacteria	E	Glycine cleavage system	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
REGS1_k127_7193005_9	243090.RB11418	2.013e-21	96.0	COG3837@1|root,COG3837@2|Bacteria	2|Bacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3,HTH_31
REGS1_k127_7193005_4	1301098.PKB_0937	1.368e-115	381.0	COG0697@1|root,COG0697@2|Bacteria,1MVHN@1224|Proteobacteria,1RM9P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	transporter	ydeK	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_7193005_1	1294143.H681_19570	4.171e-215	676.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,1RMQ0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
REGS1_k127_7193005_8	1120999.JONM01000001_gene1464	4.107e-33	133.0	2CGWB@1|root,34C2K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7193005_3	1120999.JONM01000001_gene1465	8.518e-167	530.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,2VWVQ@28216|Betaproteobacteria	28216|Betaproteobacteria	GM	Male sterility protein	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
REGS1_k127_7320971_3	580332.Slit_1514	1.762e-192	606.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,2VH8N@28216|Betaproteobacteria,44V3E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HI0933-like protein	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
REGS1_k127_7320971_4	580332.Slit_1513	7.678e-150	480.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VJF9@28216|Betaproteobacteria,44VN5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Dienelactone hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
REGS1_k127_7320971_13	380394.Lferr_0564	2.229e-63	229.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,1RNHQ@1236|Gammaproteobacteria,2NCDB@225057|Acidithiobacillales	225057|Acidithiobacillales	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
REGS1_k127_7320971_10	580332.Slit_1511	3.137e-85	283.0	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2VR4W@28216|Betaproteobacteria,44VTC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
REGS1_k127_7320971_6	580332.Slit_1510	3.108e-127	415.0	COG0500@1|root,COG2226@2|Bacteria,1QTWC@1224|Proteobacteria,2VQ89@28216|Betaproteobacteria,44VMR@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_7320971_8	580332.Slit_1509	1.52e-114	381.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,2VGZG@28216|Betaproteobacteria,44VPU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
REGS1_k127_7320971_1	580332.Slit_2864	0.0	1286.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,44WA6@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
REGS1_k127_7320971_0	580332.Slit_1455	0.0	1306.0	COG0834@1|root,COG2203@1|root,COG5001@1|root,COG0834@2|Bacteria,COG2203@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WBU@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC and GAF sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9,SBP_bac_3
REGS1_k127_7320971_9	1144319.PMI16_00348	2.24e-86	293.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,472KF@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	ydiA	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
REGS1_k127_7320971_7	580332.Slit_1623	5.816e-126	407.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,44VNV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SpoU rRNA Methylase family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_7320971_11	395494.Galf_1592	8.661e-75	259.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,44VTG@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Segregation and condensation complex subunit ScpB	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
REGS1_k127_7320971_5	580332.Slit_1625	6.807e-140	449.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,44VJ2@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
REGS1_k127_7320971_2	580332.Slit_1626	1.282e-246	763.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,44V3N@713636|Nitrosomonadales	28216|Betaproteobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
REGS1_k127_7320971_12	1485544.JQKP01000003_gene139	7.073e-66	226.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,44VNY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
REGS1_k127_7364284_6	580332.Slit_2962	1.522e-34	133.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,44V8U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
REGS1_k127_7364284_0	580332.Slit_2963	5.189e-124	411.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,2VSUT@28216|Betaproteobacteria,44W8F@713636|Nitrosomonadales	28216|Betaproteobacteria	M	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
REGS1_k127_7364284_5	580332.Slit_2964	1.877e-39	149.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,44VYK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
REGS1_k127_7364284_1	580332.Slit_2965	1.881e-96	318.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,44VMZ@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
REGS1_k127_7364284_4	580332.Slit_2966	6.038e-50	183.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,44VX2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
REGS1_k127_7364284_2	580332.Slit_2967	6.349e-87	289.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,2VR6S@28216|Betaproteobacteria,44VQT@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	aut	-	2.7.7.70	ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_7364284_3	580332.Slit_2968	1.762e-61	213.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,44VXY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
REGS1_k127_7394451_4	580332.Slit_2828	1.815e-138	445.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJGY@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS,PAS_9,TarH
REGS1_k127_7394451_6	399795.CtesDRAFT_PD0569	2.99e-102	351.0	COG1117@1|root,COG2453@1|root,COG1117@2|Bacteria,COG2453@2|Bacteria,1P0GN@1224|Proteobacteria,2VNDH@28216|Betaproteobacteria,4AC63@80864|Comamonadaceae	28216|Betaproteobacteria	HPT	PFAM Dual specificity protein phosphatase	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	ABC_tran,DSPc
REGS1_k127_7394451_12	398578.Daci_1596	9.072e-55	194.0	COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae	28216|Betaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7394451_15	580332.Slit_0715	5.466e-27	117.0	28RKJ@1|root,2ZDZE@2|Bacteria,1P9QH@1224|Proteobacteria,2W6JD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7394451_9	748247.AZKH_2201	6.205e-90	320.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,2VP8Q@28216|Betaproteobacteria,2KV6N@206389|Rhodocyclales	206389|Rhodocyclales	T	PAC sensor signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_4
REGS1_k127_7394451_13	338969.Rfer_3572	1.625e-34	152.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,4A9QK@80864|Comamonadaceae	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
REGS1_k127_7394451_5	338969.Rfer_3573	1.216e-110	361.0	COG2204@1|root,COG2204@2|Bacteria,1N46F@1224|Proteobacteria,2W4ZF@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_7394451_7	338969.Rfer_3574	4.253e-100	337.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VP9Y@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_7394451_10	1223521.BBJX01000013_gene412	3.745e-67	235.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2WEW6@28216|Betaproteobacteria,4AJRT@80864|Comamonadaceae	28216|Betaproteobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_7394451_2	640081.Dsui_1429	1.117e-178	591.0	COG5000@1|root,COG5001@1|root,COG5000@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KV9J@206389|Rhodocyclales	206389|Rhodocyclales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_4,PAS_9,dCache_1
REGS1_k127_7394451_11	580332.Slit_0061	1.602e-59	209.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_7394451_1	580332.Slit_1450	9.034e-218	677.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,2VPZ0@28216|Betaproteobacteria,44W77@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
REGS1_k127_7394451_3	580332.Slit_2242	4.449e-155	493.0	COG0679@1|root,COG0679@2|Bacteria,1N1X9@1224|Proteobacteria,2VIM5@28216|Betaproteobacteria	28216|Betaproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
REGS1_k127_7394451_0	580332.Slit_2243	2.03e-246	767.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44V4Y@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
REGS1_k127_7394451_8	452637.Oter_2265	1.003e-92	317.0	COG3391@1|root,COG3391@2|Bacteria,46UA2@74201|Verrucomicrobia	74201|Verrucomicrobia	O	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Ig_3,NHL
REGS1_k127_7394451_14	580332.Slit_1214	7.653e-30	118.0	COG3668@1|root,COG3668@2|Bacteria,1PJWP@1224|Proteobacteria,2W88C@28216|Betaproteobacteria,44WJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_7394451_16	395494.Galf_2470	2.453e-26	110.0	COG5592@1|root,COG5592@2|Bacteria,1N4TJ@1224|Proteobacteria,2VU5X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
REGS1_k127_7409439_1	395494.Galf_0469	2.718e-254	792.0	COG2703@1|root,COG3437@1|root,COG2703@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,44VG5@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	DUF3369,HD,HD_5,Response_reg
REGS1_k127_7409439_2	395494.Galf_2061	7.886e-102	334.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VQ9H@28216|Betaproteobacteria,44VRB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_7409439_0	395494.Galf_2062	3.526e-270	868.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	EAL,GAF_2,GGDEF,HATPase_c,HisKA_2,HisKA_3,PAS_3,PAS_4,PAS_8,PAS_9,SpoIIE,dCache_1
REGS1_k127_7409439_4	159087.Daro_2521	2.258e-24	109.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,2VIUT@28216|Betaproteobacteria,2KUKV@206389|Rhodocyclales	206389|Rhodocyclales	K	RNA polymerase sigma	rpoS	-	-	ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_7409439_3	697282.Mettu_0564	2.261e-37	143.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria,1XDPT@135618|Methylococcales	135618|Methylococcales	K	SMART HTH transcriptional regulator, Crp	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
REGS1_k127_7420461_2	580332.Slit_0735	5.038e-66	228.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,44V2H@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
REGS1_k127_7420461_3	580332.Slit_0733	3.44e-60	213.0	COG2847@1|root,COG2847@2|Bacteria	2|Bacteria	P	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
REGS1_k127_7420461_4	580332.Slit_0732	7.769e-36	142.0	COG2847@1|root,COG2847@2|Bacteria,1PWY4@1224|Proteobacteria,2WCG0@28216|Betaproteobacteria,44W0E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
REGS1_k127_7420461_0	580332.Slit_0731	0.0	1106.0	COG1629@1|root,COG4771@2|Bacteria,1MW7D@1224|Proteobacteria,2VIV2@28216|Betaproteobacteria,44WKC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TonB dependent receptor	nosA	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
REGS1_k127_7420461_1	580332.Slit_0730	2.261e-175	559.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,44V9Q@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
REGS1_k127_7442971_4	580332.Slit_2814	1.246e-80	270.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,44UYX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	THUMP	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
REGS1_k127_7442971_5	580332.Slit_2815	2.819e-76	261.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,44VVU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterised protein family (UPF0093)	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
REGS1_k127_7442971_1	580332.Slit_2816	1.877e-142	456.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,44W6T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC-2 type transporter	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
REGS1_k127_7442971_6	580332.Slit_2817	4.371e-71	243.0	COG0824@1|root,COG0824@2|Bacteria,1RCSP@1224|Proteobacteria,2VXA8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
REGS1_k127_7442971_0	580332.Slit_2818	1.083e-178	561.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,44VG9@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
REGS1_k127_7442971_3	580332.Slit_2819	1.409e-108	358.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,44VV2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
REGS1_k127_7442971_7	395494.Galf_2735	6.064e-53	190.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,44VZ4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
REGS1_k127_7442971_2	580332.Slit_2821	1.69e-140	454.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,44V77@713636|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
REGS1_k127_7496241_3	580332.Slit_1006	1.529e-102	335.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,44UZW@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
REGS1_k127_7496241_2	580332.Slit_2161	8.819e-173	550.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,2VH7E@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
REGS1_k127_7496241_4	580332.Slit_2169	1.445e-96	321.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,2WEFV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	3.1.2.20	ko:K01073	-	-	-	-	ko00000,ko01000	-	-	-	Lipase_GDSL_2
REGS1_k127_7496241_5	580332.Slit_2172	1.002e-36	141.0	2E75R@1|root,331PX@2|Bacteria,1NAGT@1224|Proteobacteria,2W4DV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7496241_1	580332.Slit_1665	2.597e-180	570.0	COG0687@1|root,COG0687@2|Bacteria,1MUYW@1224|Proteobacteria,2VJ59@28216|Betaproteobacteria	28216|Betaproteobacteria	E	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K02055,ko:K11069	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.11.1	-	-	SBP_bac_8
REGS1_k127_7496241_0	580332.Slit_1666	0.0	1399.0	COG2203@1|root,COG4191@1|root,COG5001@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,SBP_bac_3
REGS1_k127_7509283_4	748247.AZKH_p0369	2.822e-64	224.0	COG1463@1|root,COG1463@2|Bacteria,1MU4B@1224|Proteobacteria,2VJHA@28216|Betaproteobacteria,2KWAS@206389|Rhodocyclales	28216|Betaproteobacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
REGS1_k127_7509283_3	748247.AZKH_p0370	6.039e-79	270.0	COG3218@1|root,COG3218@2|Bacteria,1NCG2@1224|Proteobacteria,2VWSK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ABC-type transport auxiliary lipoprotein component	-	-	-	ko:K18480	-	M00669	-	-	ko00000,ko00002,ko02000	3.A.1.27.1	-	-	ABC_trans_aux
REGS1_k127_7509283_9	395494.Galf_1911	0.0005787	45.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,2VHIN@28216|Betaproteobacteria,44WAM@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
REGS1_k127_7509283_2	697282.Mettu_0562	1.094e-121	396.0	COG3437@1|root,COG3437@2|Bacteria,1QYY0@1224|Proteobacteria,1S16I@1236|Gammaproteobacteria,1XG7Y@135618|Methylococcales	135618|Methylococcales	KT	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_7509283_1	381666.H16_B0376	4.578e-146	471.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria,1KBXM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
REGS1_k127_7509283_0	314345.SPV1_10851	2.093e-161	514.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
REGS1_k127_7509283_6	264198.Reut_C6414	2.745e-49	180.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria,1KBXM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
REGS1_k127_7509283_8	1121430.JMLG01000024_gene76	2.456e-13	81.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	divK	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
REGS1_k127_7509283_5	381666.H16_B0376	9.296e-61	222.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria,1KBXM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
REGS1_k127_7509283_7	697282.Mettu_0563	1.226e-33	131.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RX1M@1236|Gammaproteobacteria,1XG7H@135618|Methylococcales	135618|Methylococcales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_7546250_3	580332.Slit_0118	1.764e-79	268.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,44UY9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
REGS1_k127_7546250_2	580332.Slit_0117	1.334e-211	659.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,44V4K@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
REGS1_k127_7546250_1	580332.Slit_0116	2.944e-306	942.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,44VJA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
REGS1_k127_7546250_0	580332.Slit_0115	0.0	1140.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,44VD7@713636|Nitrosomonadales	28216|Betaproteobacteria	E	glutamate synthase alpha subunit domain protein	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
REGS1_k127_7618660_5	1163617.SCD_n01991	2.075e-69	242.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,2VQ65@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7618660_3	1485544.JQKP01000015_gene2077	1.551e-90	307.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,44WEY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF480	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
REGS1_k127_7618660_0	1123392.AQWL01000003_gene252	1.649e-170	575.0	COG1752@1|root,COG1752@2|Bacteria,1Q82E@1224|Proteobacteria,2VMYV@28216|Betaproteobacteria,1KRYD@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7618660_7	443598.AUFA01000073_gene6349	8.644e-56	202.0	COG0583@1|root,COG0583@2|Bacteria,1NSZV@1224|Proteobacteria,2UR45@28211|Alphaproteobacteria,3K2Z2@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LysR_substrate
REGS1_k127_7618660_8	246197.MXAN_7312	9.18e-17	85.0	COG0583@1|root,COG0583@2|Bacteria,1NSZV@1224|Proteobacteria,43452@68525|delta/epsilon subdivisions,2X59G@28221|Deltaproteobacteria,2Z0AJ@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
REGS1_k127_7618660_1	314345.SPV1_02247	5.097e-154	491.0	COG0491@1|root,COG0491@2|Bacteria,1MUSY@1224|Proteobacteria	1224|Proteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_7618660_2	402626.Rpic_1123	5.434e-100	340.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria,1K1X2@119060|Burkholderiaceae	28216|Betaproteobacteria	V	PFAM secretion protein HlyD family protein	emrA	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
REGS1_k127_7618660_6	469617.FUAG_01173	1.382e-57	205.0	COG0477@1|root,COG0477@2|Bacteria,379GV@32066|Fusobacteria	32066|Fusobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
REGS1_k127_7693147_1	580332.Slit_2377	9.939e-36	139.0	COG3255@1|root,COG3255@2|Bacteria,1N93W@1224|Proteobacteria	1224|Proteobacteria	I	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
REGS1_k127_7693147_0	580332.Slit_0746	1.963e-280	864.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,44VAV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
REGS1_k127_7712601_2	580332.Slit_0712	4.028e-75	258.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria,44V4X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	AAA domain	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
REGS1_k127_7712601_0	580332.Slit_0086	9.26e-207	647.0	28ZQY@1|root,2ZMFW@2|Bacteria,1R9S7@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3800
REGS1_k127_7712601_8	580332.Slit_0717	1.488e-08	56.0	COG2050@1|root,COG2050@2|Bacteria,1NCGT@1224|Proteobacteria,2VYRW@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
REGS1_k127_7712601_5	748247.AZKH_4123	5.796e-27	112.0	COG3668@1|root,COG3668@2|Bacteria,1PUJD@1224|Proteobacteria,2WAUE@28216|Betaproteobacteria,2KZHN@206389|Rhodocyclales	206389|Rhodocyclales	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_7712601_6	13249.RPRC009738-PA	8.522e-20	104.0	COG0666@1|root,KOG4369@1|root,KOG0504@2759|Eukaryota,KOG4369@2759|Eukaryota,38I05@33154|Opisthokonta,3BHRH@33208|Metazoa,3CU4I@33213|Bilateria,41XRM@6656|Arthropoda,3SIQV@50557|Insecta,3E9DQ@33342|Paraneoptera	33208|Metazoa	T	K homology RNA-binding domain	ANKRD17	GO:0000785,GO:0001568,GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0001817,GO:0001819,GO:0001944,GO:0001955,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002831,GO:0002833,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0006275,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007346,GO:0007399,GO:0007423,GO:0007492,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009653,GO:0009887,GO:0009888,GO:0009889,GO:0009892,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009987,GO:0010506,GO:0010507,GO:0010556,GO:0010564,GO:0010639,GO:0010646,GO:0010647,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0012505,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0021700,GO:0022008,GO:0022607,GO:0023051,GO:0023052,GO:0023056,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031329,GO:0031330,GO:0031347,GO:0031349,GO:0031430,GO:0031672,GO:0031674,GO:0031965,GO:0031967,GO:0031975,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0039531,GO:0039533,GO:0039535,GO:0040011,GO:0042692,GO:0042742,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043122,GO:0043123,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043292,GO:0043900,GO:0043902,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045214,GO:0045595,GO:0045596,GO:0045787,GO:0045931,GO:0046530,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050688,GO:0050776,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051052,GO:0051093,GO:0051128,GO:0051129,GO:0051146,GO:0051147,GO:0051148,GO:0051150,GO:0051151,GO:0051171,GO:0051239,GO:0051240,GO:0051704,GO:0051707,GO:0051716,GO:0051726,GO:0055001,GO:0055002,GO:0060255,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071695,GO:0071840,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090068,GO:0090596,GO:0097435,GO:0098542,GO:0099080,GO:0099081,GO:0099512,GO:1900087,GO:1900245,GO:1900246,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902531,GO:1902533,GO:1902806,GO:1902808,GO:1903146,GO:1903147,GO:2000045,GO:2000112	-	ko:K16726	-	-	-	-	ko00000,ko03036	-	-	-	Ank_2,Ank_4,KH_1
REGS1_k127_7712601_4	580332.Slit_0717	8.816e-67	231.0	COG2050@1|root,COG2050@2|Bacteria,1NCGT@1224|Proteobacteria,2VYRW@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
REGS1_k127_7712601_3	666681.M301_2749	5.445e-72	248.0	2BNSJ@1|root,32HG4@2|Bacteria,1MV5R@1224|Proteobacteria,2VR61@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
REGS1_k127_7712601_1	580332.Slit_0718	4.914e-196	616.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,44WA4@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_7712601_7	269482.Bcep1808_0165	1.549e-10	66.0	2EGYW@1|root,33AR0@2|Bacteria,1NM8U@1224|Proteobacteria,2VZ2G@28216|Betaproteobacteria,1K974@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7797198_6	580332.Slit_0907	5.013e-77	258.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,2VQYS@28216|Betaproteobacteria,44WBZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF269	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
REGS1_k127_7797198_9	580332.Slit_0906	3.294e-55	201.0	COG3086@1|root,COG3086@2|Bacteria,1NMXY@1224|Proteobacteria,2W88E@28216|Betaproteobacteria,44WJ3@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Positive regulator of sigma(E), RseC/MucC	-	-	-	ko:K03803	-	-	-	-	ko00000,ko03021	-	-	-	RseC_MucC
REGS1_k127_7797198_7	580332.Slit_0905	2.322e-67	237.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,2VUUQ@28216|Betaproteobacteria,44WF9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
REGS1_k127_7797198_1	580332.Slit_0904	7.113e-258	805.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2VJNA@28216|Betaproteobacteria,44W97@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifN	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
REGS1_k127_7797198_0	580332.Slit_0903	3.859e-296	910.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,2VJ11@28216|Betaproteobacteria,44WB6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifE	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
REGS1_k127_7797198_5	358220.C380_11925	4.029e-115	382.0	COG1106@1|root,COG1106@2|Bacteria,1MVU0@1224|Proteobacteria,2VMJQ@28216|Betaproteobacteria,4ACCE@80864|Comamonadaceae	28216|Betaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
REGS1_k127_7797198_11	1123367.C666_14635	1.596e-23	102.0	COG3609@1|root,COG3609@2|Bacteria,1PDAR@1224|Proteobacteria,2VYMZ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH	-	-	-	-	-	-	-	-	-	-	-	-	ParD_antitoxin
REGS1_k127_7797198_2	580332.Slit_0902	4.493e-172	543.0	2E2KC@1|root,32XPP@2|Bacteria,1R4ZI@1224|Proteobacteria,2VM8Z@28216|Betaproteobacteria,44WDX@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7797198_3	580332.Slit_0901	3.346e-130	421.0	COG1413@1|root,COG1413@2|Bacteria,1N94K@1224|Proteobacteria,2VIQ1@28216|Betaproteobacteria,44W8M@713636|Nitrosomonadales	28216|Betaproteobacteria	C	LRV protein FeS4 cluster	-	-	-	-	-	-	-	-	-	-	-	-	LRV,LRV_FeS
REGS1_k127_7797198_8	580332.Slit_0900	7.599e-66	229.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,2VUTI@28216|Betaproteobacteria,44WGX@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_7797198_4	580332.Slit_0899	5.049e-128	411.0	COG4148@1|root,COG4148@2|Bacteria,1MU8K@1224|Proteobacteria,2VJ3B@28216|Betaproteobacteria,44W54@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TOBE domain	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran,TOBE
REGS1_k127_7844124_7	580332.Slit_2240	5.449e-48	175.0	2DE4Z@1|root,2ZKI5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gal_Lectin
REGS1_k127_7844124_1	580332.Slit_2239	3.524e-149	475.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2VKZJ@28216|Betaproteobacteria,44UYY@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Haloacid dehalogenase domain protein hydrolase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	DUF4072,HAD
REGS1_k127_7844124_3	395494.Galf_2157	4.634e-127	415.0	COG3129@1|root,COG3129@2|Bacteria,1MUI4@1224|Proteobacteria,2VKKW@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Specifically methylates the adenine in position 1618 of 23S rRNA	rlmF	-	2.1.1.181	ko:K06970	-	-	R07232	RC00003,RC00335	ko00000,ko01000,ko03009	-	-	-	Methyltransf_10
REGS1_k127_7844124_10	1173020.Cha6605_0777	1.453e-07	59.0	2BXHP@1|root,33F0K@2|Bacteria,1GG8M@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7844124_6	404380.Gbem_2876	1.252e-54	194.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,42SZ8@68525|delta/epsilon subdivisions,2WP2Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
REGS1_k127_7844124_2	580332.Slit_2237	4.062e-149	475.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,2VM5Q@28216|Betaproteobacteria,44WCW@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
REGS1_k127_7844124_9	322710.Avin_40590	1.514e-44	163.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,1SC8G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_7844124_8	322710.Avin_40600	1.022e-44	164.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,1SCNC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
REGS1_k127_7844124_0	1485544.JQKP01000002_gene1598	0.0	1913.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,44UYD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
REGS1_k127_7844124_4	1430440.MGMSRv2_3810	1e-63	234.0	COG4251@1|root,COG5001@1|root,COG4251@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,MASE2,PAS,PAS_3,PAS_4,PAS_8,PAS_9
REGS1_k127_7878473_0	1283300.ATXB01000001_gene42	6.75e-274	851.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RQMD@1236|Gammaproteobacteria,1XGZF@135618|Methylococcales	135618|Methylococcales	G	Carbohydrate phosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphorylase
REGS1_k127_7878473_1	580332.Slit_1867	1.238e-219	689.0	COG2230@1|root,COG2230@2|Bacteria,1MX3U@1224|Proteobacteria,2VIPR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
REGS1_k127_7878473_2	580332.Slit_1866	4.443e-33	131.0	COG5569@1|root,COG5569@2|Bacteria,1NGSZ@1224|Proteobacteria,2VXT4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Copper binding periplasmic protein CusF	-	-	-	-	-	-	-	-	-	-	-	-	CusF_Ec
REGS1_k127_7878473_3	580332.Slit_1865	7.043e-09	57.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,44VI6@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM heavy metal efflux pump, CzcA family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
REGS1_k127_7889707_2	1163617.SCD_n00718	1.022e-128	416.0	COG3437@1|root,COG3437@2|Bacteria,1PDX2@1224|Proteobacteria,2VMIS@28216|Betaproteobacteria	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
REGS1_k127_7889707_1	338969.Rfer_2356	4.291e-188	604.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJNX@28216|Betaproteobacteria,4AJWE@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
REGS1_k127_7889707_0	697282.Mettu_4224	0.0	1289.0	COG1196@1|root,COG1352@1|root,COG2201@1|root,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,1T2RH@1236|Gammaproteobacteria,1XE6G@135618|Methylococcales	135618|Methylococcales	NT	PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
REGS1_k127_7889707_3	697282.Mettu_0564	9.599e-121	392.0	COG0664@1|root,COG0664@2|Bacteria,1NEQM@1224|Proteobacteria,1RP0B@1236|Gammaproteobacteria,1XDPT@135618|Methylococcales	135618|Methylococcales	K	SMART HTH transcriptional regulator, Crp	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2
REGS1_k127_7889707_8	28229.ND2E_0198	2.5e-05	48.0	COG3275@1|root,COG5001@1|root,COG3275@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,CHASE,EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_9,dCache_1,sCache_3_2
REGS1_k127_7889707_6	1123401.JHYQ01000006_gene67	2.24e-33	134.0	COG3461@1|root,COG3461@2|Bacteria,1MZZN@1224|Proteobacteria,1S688@1236|Gammaproteobacteria,460V9@72273|Thiotrichales	72273|Thiotrichales	S	Evidence 4 Homologs of previously reported genes of	-	-	-	ko:K09700	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_7889707_7	338969.Rfer_3274	6.83e-16	81.0	COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria,2VXPK@28216|Betaproteobacteria,4AFXD@80864|Comamonadaceae	28216|Betaproteobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
REGS1_k127_7889707_4	1120999.JONM01000001_gene1495	1.685e-103	347.0	COG1295@1|root,COG1295@2|Bacteria,1R9UY@1224|Proteobacteria,2VJV0@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
REGS1_k127_7889707_5	331869.BAL199_00165	3.935e-86	295.0	COG1262@1|root,COG4249@1|root,COG1262@2|Bacteria,COG4249@2|Bacteria,1MXFD@1224|Proteobacteria,2TRW5@28211|Alphaproteobacteria,4BQPK@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	M	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PG_binding_1,Peptidase_C14,SH3_3
REGS1_k127_7929736_4	580332.Slit_2370	5.793e-66	225.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,44VG7@713636|Nitrosomonadales	28216|Betaproteobacteria	D	TIGRFAM cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
REGS1_k127_7929736_2	580332.Slit_2371	6.888e-147	469.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,44VHS@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
REGS1_k127_7929736_3	580332.Slit_2173	4.218e-75	262.0	2DMIH@1|root,32RT1@2|Bacteria,1RDKU@1224|Proteobacteria,2VR1F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7929736_0	580332.Slit_2298	1.665e-250	777.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,44VEY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
REGS1_k127_7929736_5	1485544.JQKP01000013_gene1836	1.986e-50	181.0	COG5652@1|root,COG5652@2|Bacteria,1NGE7@1224|Proteobacteria,2W5S7@28216|Betaproteobacteria,44WK1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
REGS1_k127_7929736_1	580332.Slit_2299	2.292e-159	504.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,44V01@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
REGS1_k127_7929736_6	580332.Slit_2301	4.888e-41	153.0	2DMT2@1|root,32TGY@2|Bacteria,1R3E1@1224|Proteobacteria,2VUA9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7988706_2	580332.Slit_0311	2.502e-29	117.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,44V3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
REGS1_k127_7988706_0	580332.Slit_0310	4.899e-157	498.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,44VQ9@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
REGS1_k127_7988706_1	580332.Slit_0305	4.372e-86	288.0	COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,2VHJI@28216|Betaproteobacteria,44VQR@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ferritin-like domain	dps	-	-	ko:K04047	-	-	-	-	ko00000,ko03036	-	-	-	Ferritin
REGS1_k127_7988706_3	580332.Slit_0300	7.995e-25	106.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,44VSW@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_8094966_2	580332.Slit_2445	8.033e-254	788.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,44V8P@713636|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
REGS1_k127_8094966_1	580332.Slit_2444	0.0	1077.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,44V7T@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_8094966_5	580332.Slit_2442	6.709e-32	125.0	COG3360@1|root,COG3360@2|Bacteria,1PW6C@1224|Proteobacteria,2VXDE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
REGS1_k127_8094966_4	1198452.Jab_2c13890	4.471e-58	206.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,2VW7M@28216|Betaproteobacteria	28216|Betaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
REGS1_k127_8094966_0	290315.Clim_0129	0.0	1349.0	COG4096@1|root,COG4096@2|Bacteria	2|Bacteria	L	type I site-specific deoxyribonuclease activity	hsdR_2	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
REGS1_k127_8094966_3	278957.ABEA03000106_gene1790	4.081e-123	411.0	28HAW@1|root,2Z7N4@2|Bacteria	2|Bacteria	S	PFAM KilA, N-terminal APSES-type HTH, DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	KilA-N
REGS1_k127_8109976_9	580332.Slit_1281	2.482e-41	155.0	29X95@1|root,30IYK@2|Bacteria,1Q9AG@1224|Proteobacteria,2WCGR@28216|Betaproteobacteria,44W1V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845
REGS1_k127_8109976_6	580332.Slit_1282	2.703e-109	357.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,2VI4M@28216|Betaproteobacteria,44VQ8@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
REGS1_k127_8109976_2	580332.Slit_1283	2.229e-171	540.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,2VHYP@28216|Betaproteobacteria,44VDI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
REGS1_k127_8109976_4	1485544.JQKP01000003_gene269	7.082e-117	379.0	COG1381@1|root,COG1381@2|Bacteria,1RHIC@1224|Proteobacteria,2VJUC@28216|Betaproteobacteria,44V76@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
REGS1_k127_8109976_3	580332.Slit_1285	3.383e-138	443.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,2VHY7@28216|Betaproteobacteria,44VH1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
REGS1_k127_8109976_8	580332.Slit_1286	9.174e-52	191.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,2VT0P@28216|Betaproteobacteria,44VYY@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
REGS1_k127_8109976_1	580332.Slit_1287	3.113e-201	631.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,44V3T@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
REGS1_k127_8109976_5	580332.Slit_1291	4.935e-113	374.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,44VC1@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
REGS1_k127_8109976_0	1485544.JQKP01000013_gene1796	5e-324	1004.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,44VJW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
REGS1_k127_8109976_7	580332.Slit_1294	2.233e-97	320.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,44VRI@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
REGS1_k127_8109976_10	580332.Slit_1295	4.306e-41	151.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,44VB8@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphorylase superfamily	mtaP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_8136163_0	395494.Galf_2497	0.0	1070.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,44VCD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF3400)	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
REGS1_k127_8136163_3	580332.Slit_0332	3.857e-202	642.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria,44W4N@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8136163_4	580332.Slit_0331	3.622e-198	625.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,44VNZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	TIGRFAM phosphate regulon sensor kinase PhoR	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
REGS1_k127_8136163_5	580332.Slit_0330	7.695e-134	430.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,44V17@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Two component transcriptional regulator PhoB, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_8136163_2	395494.Galf_2501	7.819e-246	766.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,44V0T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
REGS1_k127_8136163_10	324057.Pjdr2_0698	6.674e-05	53.0	COG3170@1|root,COG4099@1|root,COG4932@1|root,COG3170@2|Bacteria,COG4099@2|Bacteria,COG4932@2|Bacteria,1UJE7@1239|Firmicutes,4IT6J@91061|Bacilli,2778B@186822|Paenibacillaceae	91061|Bacilli	M	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,SLH
REGS1_k127_8136163_6	580332.Slit_2677	8.125e-119	383.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,2VI7T@28216|Betaproteobacteria,44VNE@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
REGS1_k127_8136163_8	580332.Slit_2678	4.714e-78	263.0	COG2703@1|root,COG2703@2|Bacteria,1RK9A@1224|Proteobacteria,2VT8G@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_8136163_1	580332.Slit_2679	9.066e-290	898.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,44V3U@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_8136163_9	580332.Slit_2680	3.135e-73	252.0	2ARZT@1|root,31HBY@2|Bacteria,1RM6G@1224|Proteobacteria,2VT5G@28216|Betaproteobacteria,44WIK@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8136163_7	1192124.LIG30_1561	1.375e-112	381.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,1K0NI@119060|Burkholderiaceae	28216|Betaproteobacteria	H	receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
REGS1_k127_8164609_8	395494.Galf_2691	5.658e-12	66.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,44V5F@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	NAD(P)H-binding	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
REGS1_k127_8164609_7	1408445.JHXP01000009_gene2783	4.144e-13	78.0	COG5492@1|root,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,1SZNY@1236|Gammaproteobacteria,1JFM8@118969|Legionellales	1224|Proteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3494
REGS1_k127_8164609_6	161528.ED21_23761	5.008e-71	253.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2UBMV@28211|Alphaproteobacteria,2K6P2@204457|Sphingomonadales	204457|Sphingomonadales	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8164609_2	580332.Slit_1351	8.892e-157	498.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VICP@28216|Betaproteobacteria,44VDG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
REGS1_k127_8164609_3	580332.Slit_1350	1.204e-156	497.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,44VG8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
REGS1_k127_8164609_5	395494.Galf_1490	4.661e-82	277.0	COG2353@1|root,COG2353@2|Bacteria,1RJFZ@1224|Proteobacteria,2VQHC@28216|Betaproteobacteria,44VSZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
REGS1_k127_8164609_4	580332.Slit_1348	2.159e-95	316.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria,44V7N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
REGS1_k127_8164609_1	580332.Slit_1347	6.479e-197	618.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,44V89@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
REGS1_k127_8164609_0	395494.Galf_1757	0.0	1439.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria,44W5X@713636|Nitrosomonadales	28216|Betaproteobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
REGS1_k127_8173910_5	580332.Slit_1266	6.723e-52	184.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,44VXA@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
REGS1_k127_8173910_4	580332.Slit_1267	8.134e-112	362.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,44VGC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
REGS1_k127_8173910_3	580332.Slit_1268	3.565e-149	477.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,44V60@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_8173910_2	580332.Slit_1269	2.066e-160	514.0	COG2114@1|root,COG2114@2|Bacteria,1RD0X@1224|Proteobacteria,2VS0D@28216|Betaproteobacteria,44VWF@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,PEGA
REGS1_k127_8173910_6	580332.Slit_1270	2.719e-40	153.0	COG3063@1|root,COG3063@2|Bacteria,1N7DT@1224|Proteobacteria,2VW37@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8173910_1	580332.Slit_1271	6.799e-179	568.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
REGS1_k127_8173910_7	580332.Slit_1272	1.173e-17	88.0	2DU64@1|root,33P2Y@2|Bacteria,1PVCP@1224|Proteobacteria,2WBNR@28216|Betaproteobacteria,44WP5@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8173910_0	580332.Slit_1273	1.601e-185	582.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,2VHA7@28216|Betaproteobacteria,44VJB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_8200229_2	580332.Slit_2520	1.557e-166	524.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,44VCH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
REGS1_k127_8200229_3	395494.Galf_0418	1.853e-78	266.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,44VR3@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
REGS1_k127_8200229_0	522306.CAP2UW1_2424	2.189e-266	830.0	COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,2VIMQ@28216|Betaproteobacteria,1KQHI@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	S	SbmA/BacA-like family	-	-	-	ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.203.11,3.A.1.203.4	-	-	ABC_membrane_2,ABC_tran
REGS1_k127_8200229_4	580332.Slit_1187	4.359e-11	64.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VI3T@28216|Betaproteobacteria,44W74@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.17	ko:K01908	ko00640,ko01100,map00640,map01100	-	R00926,R01354	RC00004,RC00043,RC00070,RC02816	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
REGS1_k127_8200229_1	580332.Slit_2532	1.171e-265	822.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,44V28@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
REGS1_k127_8201852_0	580332.Slit_0267	2.707e-191	598.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,44V8C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
REGS1_k127_8201852_3	1288494.EBAPG3_8860	1.919e-62	223.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,371TG@32003|Nitrosomonadales	28216|Betaproteobacteria	H	uroporphyrinogen III synthase	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
REGS1_k127_8201852_2	580332.Slit_0269	6.592e-134	436.0	COG2959@1|root,COG2959@2|Bacteria,1MY3A@1224|Proteobacteria,2VMG1@28216|Betaproteobacteria,44V4N@713636|Nitrosomonadales	28216|Betaproteobacteria	H	HemX, putative uroporphyrinogen-III C-methyltransferase	hemX	-	2.1.1.107,4.2.1.75	ko:K02496,ko:K13543	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,HemX
REGS1_k127_8201852_1	580332.Slit_0270	5.35e-163	521.0	COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,2VK6P@28216|Betaproteobacteria,44VZN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	HemY protein N-terminus	hemY	-	-	ko:K02498	-	-	-	-	ko00000	-	-	-	HemY_N,TPR_12
REGS1_k127_8250572_16	28229.ND2E_3150	3.319e-19	89.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,1RYX7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve
REGS1_k127_8250572_4	580332.Slit_1036	1.218e-167	530.0	COG1270@1|root,COG1270@2|Bacteria,1MWCK@1224|Proteobacteria,2VH7X@28216|Betaproteobacteria,44VR6@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
REGS1_k127_8250572_2	395494.Galf_1977	4.642e-235	731.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,44VMN@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Elongation factor Tu GTP binding domain	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
REGS1_k127_8250572_3	580332.Slit_1034	4.731e-185	581.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2VJH9@28216|Betaproteobacteria,44V50@713636|Nitrosomonadales	28216|Betaproteobacteria	EH	Phosphoadenosine phosphosulfate reductase family	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
REGS1_k127_8250572_8	1485544.JQKP01000003_gene207	6.437e-123	400.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2VIR0@28216|Betaproteobacteria,44V6T@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
REGS1_k127_8250572_11	153948.NAL212_0643	1.119e-69	241.0	COG3749@1|root,COG3749@2|Bacteria,1RJR9@1224|Proteobacteria,2VSQB@28216|Betaproteobacteria,3741S@32003|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Uncharacterised conserved protein UCP030820	-	-	-	-	-	-	-	-	-	-	-	-	DUF934
REGS1_k127_8250572_0	395494.Galf_1981	1.426e-307	949.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,44VXW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein	cysI	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
REGS1_k127_8250572_7	395494.Galf_1983	4.571e-130	419.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2VMUD@28216|Betaproteobacteria,44VN0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
REGS1_k127_8250572_5	580332.Slit_1030	4.645e-154	490.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,44V21@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
REGS1_k127_8250572_10	1123487.KB892835_gene3297	1.96e-95	323.0	COG0778@1|root,COG0778@2|Bacteria,1NIJ8@1224|Proteobacteria,2VNBD@28216|Betaproteobacteria,2KXG2@206389|Rhodocyclales	206389|Rhodocyclales	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_8250572_1	580332.Slit_1028	6.416e-263	817.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,44V0N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
REGS1_k127_8250572_12	580332.Slit_1027	3.104e-61	213.0	COG0454@1|root,COG0456@2|Bacteria,1PWZN@1224|Proteobacteria,2WCHN@28216|Betaproteobacteria,44W43@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
REGS1_k127_8250572_15	580332.Slit_1027	2.769e-28	118.0	COG0454@1|root,COG0456@2|Bacteria,1PWZN@1224|Proteobacteria,2WCHN@28216|Betaproteobacteria,44W43@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Protein of unknown function (DUF3579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3579
REGS1_k127_8250572_9	614083.AWQR01000025_gene3676	7.619e-98	333.0	COG2199@1|root,COG3706@2|Bacteria,1RCJQ@1224|Proteobacteria,2VUTS@28216|Betaproteobacteria,4AHMR@80864|Comamonadaceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_8250572_14	1485544.JQKP01000018_gene594	1.605e-35	137.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,44W0I@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
REGS1_k127_8250572_6	580332.Slit_1024	2.006e-140	449.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,44VA2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_8252192_2	580332.Slit_2396	7.02e-91	302.0	COG4660@1|root,COG4660@2|Bacteria,1MW6N@1224|Proteobacteria,2VNWT@28216|Betaproteobacteria,44UYJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03613	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
REGS1_k127_8252192_1	580332.Slit_2397	9.622e-117	383.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,2VIRB@28216|Betaproteobacteria,44VCE@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
REGS1_k127_8252192_4	580332.Slit_2398	7.276e-80	267.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,44VU7@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
REGS1_k127_8252192_3	580332.Slit_2399	4.412e-80	271.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,2VQ7P@28216|Betaproteobacteria,44WG0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cobalamin adenosyltransferase	yvqK	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
REGS1_k127_8252192_6	870187.Thini_4253	1.408e-17	90.0	COG0517@1|root,COG0517@2|Bacteria,1RJTX@1224|Proteobacteria,1S6K2@1236|Gammaproteobacteria,461DK@72273|Thiotrichales	72273|Thiotrichales	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
REGS1_k127_8252192_0	580332.Slit_2400	2.862e-140	449.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,2VIME@28216|Betaproteobacteria,44VGT@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_8252192_5	580332.Slit_2401	9.089e-64	219.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,2VHHT@28216|Betaproteobacteria	28216|Betaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
REGS1_k127_8374527_1	1288494.EBAPG3_25000	2.104e-53	193.0	COG0642@1|root,COG0784@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,374RC@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HAMP,HATPase_c,HisKA,Hpt,MHYT,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
REGS1_k127_8374527_0	395494.Galf_1588	1.395e-168	551.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2VH4X@28216|Betaproteobacteria,44WKU@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM TonB-dependent receptor plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
REGS1_k127_8391645_0	580332.Slit_0650	2.779e-259	801.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,44V8Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
REGS1_k127_8391645_3	580332.Slit_0651	1.386e-85	286.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,44VU0@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
REGS1_k127_8391645_1	580332.Slit_0652	4.111e-171	543.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,44VG2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
REGS1_k127_8391645_2	580332.Slit_0653	2.452e-106	346.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,44V83@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
REGS1_k127_8393411_4	580332.Slit_0742	6.442e-52	185.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,44VKC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
REGS1_k127_8393411_1	395494.Galf_2310	5.799e-88	294.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,2VRH2@28216|Betaproteobacteria,44VS8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
REGS1_k127_8393411_3	580332.Slit_0744	6.77e-69	237.0	COG0526@1|root,COG0526@2|Bacteria,1N4HY@1224|Proteobacteria,2VSKM@28216|Betaproteobacteria,44VXP@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Glutathione peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_8393411_0	580332.Slit_0745	3.862e-104	348.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria,44VRN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
REGS1_k127_8393411_2	580332.Slit_0746	4.582e-84	279.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,44VAV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
REGS1_k127_8416201_2	580332.Slit_1520	3.286e-271	837.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,44VBY@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_8416201_0	580332.Slit_1608	0.0	1066.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VHW2@28216|Betaproteobacteria,44W82@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	hoxF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_8416201_4	580332.Slit_1609	3.779e-154	489.0	COG1034@1|root,COG1034@2|Bacteria,1QVC7@1224|Proteobacteria,2VI6U@28216|Betaproteobacteria,44W9N@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	hoxU	-	1.12.1.2	ko:K18006	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
REGS1_k127_8416201_5	580332.Slit_1610	1.391e-114	370.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,2VJH8@28216|Betaproteobacteria,44WAW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	hoxY	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
REGS1_k127_8416201_1	580332.Slit_1611	9.792e-313	959.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,44WEG@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hoxH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
REGS1_k127_8416201_10	1089447.RHAA1_00939	1.966e-09	58.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,1S9CP@1236|Gammaproteobacteria,1Y91X@135625|Pasteurellales	135625|Pasteurellales	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
REGS1_k127_8416201_8	1502770.JQMG01000001_gene2163	2.062e-32	129.0	COG3093@1|root,COG3093@2|Bacteria,1N2TD@1224|Proteobacteria,2WFU8@28216|Betaproteobacteria	28216|Betaproteobacteria	K	TIGRFAM Addiction module antidote protein, HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
REGS1_k127_8416201_7	580332.Slit_1612	3.487e-61	214.0	COG0680@1|root,COG0680@2|Bacteria,1MZE1@1224|Proteobacteria,2VTPX@28216|Betaproteobacteria,44WKQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase maturation protease	hoxW	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8416201_6	338969.Rfer_2187	1.826e-76	261.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria,4AHE5@80864|Comamonadaceae	28216|Betaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	porC	-	1.2.1.58,1.2.7.1	ko:K00172,ko:K18357	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
REGS1_k127_8416201_3	395494.Galf_0061	1.021e-238	741.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2W99Y@28216|Betaproteobacteria,44WKY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	-	-	1.2.7.1	ko:K00169,ko:K03737	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034,R10866	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
REGS1_k127_8454170_3	580332.Slit_0855	4.042e-33	130.0	2E5WI@1|root,330KJ@2|Bacteria,1N6RI@1224|Proteobacteria,2VXJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Nif11 domain	-	-	-	-	-	-	-	-	-	-	-	-	Nif11
REGS1_k127_8454170_0	580332.Slit_0856	1.101e-307	945.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,2WHK4@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Nif-specific regulatory protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
REGS1_k127_8454170_1	580332.Slit_0857	2.686e-273	850.0	COG4191@1|root,COG4191@2|Bacteria,1MXRR@1224|Proteobacteria,2VN7B@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS PAC sensor signal transduction histidine kinase	-	-	2.7.13.1	ko:K05962	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c,PAS
REGS1_k127_8454170_2	580332.Slit_0858	1.418e-88	295.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VH0C@28216|Betaproteobacteria,44VIU@713636|Nitrosomonadales	1224|Proteobacteria	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
REGS1_k127_8460934_3	580332.Slit_0665	9.987e-84	280.0	COG1451@1|root,COG1451@2|Bacteria,1RDJ9@1224|Proteobacteria,2VR4I@28216|Betaproteobacteria,44VT2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	WLM domain	ygjP	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
REGS1_k127_8460934_0	580332.Slit_0667	6.934e-257	799.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VP3@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	dbpA	GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	3.6.4.13	ko:K05591	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DEAD,DbpA,Helicase_C
REGS1_k127_8460934_2	580332.Slit_2824	3.079e-102	338.0	COG1187@1|root,COG1187@2|Bacteria,1PYTZ@1224|Proteobacteria,2VNU1@28216|Betaproteobacteria,44VFC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	-	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	S4
REGS1_k127_8460934_5	580332.Slit_2825	1.298e-31	124.0	COG4628@1|root,COG4628@2|Bacteria,1N7DG@1224|Proteobacteria,2VW2Y@28216|Betaproteobacteria,44W1K@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DNA-binding protein VF530	-	-	-	-	-	-	-	-	-	-	-	-	VF530
REGS1_k127_8460934_1	261292.Nit79A3_0765	8.222e-146	470.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,2VJ0H@28216|Betaproteobacteria,372PD@32003|Nitrosomonadales	28216|Betaproteobacteria	DT	PFAM RIO-like kinase	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
REGS1_k127_8460934_4	580332.Slit_2775	1.093e-40	151.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2VUQP@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_8464807_2	580332.Slit_0254	7.299e-35	136.0	COG1729@1|root,COG1729@2|Bacteria,1P69R@1224|Proteobacteria,2W622@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8464807_0	580332.Slit_0255	3.049e-233	726.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,44VIX@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
REGS1_k127_8464807_1	580332.Slit_0256	4.921e-69	239.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,44VAN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_8467240_6	580332.Slit_0290	1.481e-09	60.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,44V5S@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiF	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
REGS1_k127_8467240_3	580332.Slit_0291	5.6e-187	587.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,44UYZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
REGS1_k127_8467240_5	580332.Slit_0292	9.954e-43	156.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,44W2K@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory protein, Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
REGS1_k127_8467240_0	580332.Slit_0293	7.043e-318	975.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,44VKQ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme formylation region	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
REGS1_k127_8467240_1	580332.Slit_0294	4.034e-261	807.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,44V8B@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
REGS1_k127_8467240_4	580332.Slit_0295	1.406e-92	309.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,44VTE@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
REGS1_k127_8467240_2	580332.Slit_0296	6.195e-205	638.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,44VJH@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
REGS1_k127_8467240_7	580332.Slit_0538	0.0003164	47.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,44W47@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
REGS1_k127_8476720_2	365046.Rta_19320	9.074e-104	359.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2W05Y@28216|Betaproteobacteria,4AGS3@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	HAMP,MCPsignal,dCache_1
REGS1_k127_8476720_10	365046.Rta_19310	3.437e-35	141.0	COG0835@1|root,COG0835@2|Bacteria,1Q0RG@1224|Proteobacteria,2W5MM@28216|Betaproteobacteria,4AIWF@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_8476720_9	365046.Rta_19290	1.157e-46	172.0	COG0745@1|root,COG0745@2|Bacteria	365046.Rta_19290|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8476720_6	365046.Rta_19280	9.456e-68	239.0	COG0745@1|root,COG0745@2|Bacteria,1N2T7@1224|Proteobacteria,2VSUA@28216|Betaproteobacteria,4AIKH@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_8476720_1	580332.Slit_2685	7.283e-109	358.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,44V3G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
REGS1_k127_8476720_5	697282.Mettu_1476	2.467e-75	258.0	COG3916@1|root,COG3916@2|Bacteria,1RB3V@1224|Proteobacteria,1S404@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Acyl-homoserine-lactone synthase	vanI	-	2.3.1.184	ko:K13060,ko:K13061	ko00270,ko01100,ko02020,ko02024,ko02025,map00270,map01100,map02020,map02024,map02025	-	R08939,R08940	RC00021,RC00039	ko00000,ko00001,ko01000	-	-	-	Autoind_synth
REGS1_k127_8476720_11	697282.Mettu_1480	3.641e-28	118.0	2E2SJ@1|root,32XUU@2|Bacteria,1N2UD@1224|Proteobacteria,1SF8J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4902)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4902
REGS1_k127_8476720_3	1005048.CFU_1957	3.39e-85	288.0	COG2197@1|root,COG2197@2|Bacteria,1R4TP@1224|Proteobacteria,2VQJX@28216|Betaproteobacteria,4777P@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Autoinducer binding domain	-	-	-	ko:K07782	ko02020,ko02024,ko02026,map02020,map02024,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	Autoind_bind,GerE
REGS1_k127_8476720_4	649639.Bcell_3136	7.979e-83	286.0	COG1809@1|root,COG1809@2|Bacteria,1V20V@1239|Firmicutes,4HDSM@91061|Bacilli,1ZEWC@1386|Bacillus	91061|Bacilli	S	synthase	yitD	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
REGS1_k127_8476720_8	1120972.AUMH01000004_gene1526	3.916e-56	203.0	COG3565@1|root,COG3565@2|Bacteria,1V6AX@1239|Firmicutes,4HIET@91061|Bacilli	91061|Bacilli	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
REGS1_k127_8476720_7	1382358.JHVN01000011_gene2017	1.241e-59	214.0	COG2045@1|root,COG2045@2|Bacteria,1TTEV@1239|Firmicutes,4HGDY@91061|Bacilli	91061|Bacilli	H	Belongs to the ComB family	-	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
REGS1_k127_8476720_12	1112212.JH584235_gene387	8.764e-12	70.0	COG1403@1|root,COG1403@2|Bacteria,1NEG4@1224|Proteobacteria,2UUVK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8476720_0	580332.Slit_1305	0.0	1220.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,44VIM@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
REGS1_k127_8521538_2	1234364.AMSF01000055_gene1089	1.924e-73	254.0	COG0745@1|root,COG0745@2|Bacteria,1RA00@1224|Proteobacteria,1S23N@1236|Gammaproteobacteria,1X3BY@135614|Xanthomonadales	135614|Xanthomonadales	K	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_8521538_1	580332.Slit_0262	2.421e-172	552.0	COG4251@1|root,COG4251@2|Bacteria,1QZS1@1224|Proteobacteria,2WHY8@28216|Betaproteobacteria	28216|Betaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_8521538_0	580332.Slit_0264	5.841e-180	574.0	2AFYG@1|root,31628@2|Bacteria,1PWQT@1224|Proteobacteria,2WC9D@28216|Betaproteobacteria,44VMT@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8521538_3	580332.Slit_2858	1.74e-42	157.0	2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria,44W3F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
REGS1_k127_8536234_0	580332.Slit_1850	2.379e-220	685.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,44VHW@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_8536234_2	580332.Slit_1849	6.237e-52	190.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,44W0B@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
REGS1_k127_8536234_3	580332.Slit_1849	2.16e-47	176.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,44W0B@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
REGS1_k127_8536234_1	580332.Slit_1848	1.28e-155	501.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,44V9V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8553319_2	395494.Galf_1821	7.557e-59	204.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,44V1P@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_8553319_3	580332.Slit_2220	2.24e-52	188.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,44VYU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
REGS1_k127_8553319_0	580332.Slit_2221	3.181e-183	574.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities AAA_3	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_8553319_1	580332.Slit_2222	1.355e-87	290.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria,44WBQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_8570078_0	580332.Slit_2866	1.051e-193	606.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,44V4U@713636|Nitrosomonadales	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
REGS1_k127_8570078_2	580332.Slit_2868	2.886e-134	432.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,2VN04@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
REGS1_k127_8570078_4	580332.Slit_2753	8.598e-46	166.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VW9W@28216|Betaproteobacteria,44WPG@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_8570078_5	580332.Slit_2773	1.139e-36	139.0	COG2345@1|root,COG2345@2|Bacteria,1N9W3@1224|Proteobacteria,2VWG0@28216|Betaproteobacteria,44WNR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8570078_3	580332.Slit_1159	1.151e-60	210.0	2AY99@1|root,31QBJ@2|Bacteria,1RI92@1224|Proteobacteria,2VSPH@28216|Betaproteobacteria,44WGF@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8570078_1	1216976.AX27061_1584	1.192e-147	472.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,1MVN2@1224|Proteobacteria,2VJMQ@28216|Betaproteobacteria,3T3BM@506|Alcaligenaceae	28216|Betaproteobacteria	HJM	Belongs to the	cphA1	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
REGS1_k127_8574290_0	580332.Slit_2036	1.483e-189	595.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VHKK@28216|Betaproteobacteria,44VMM@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
REGS1_k127_8574290_6	1123261.AXDW01000011_gene573	1.902e-18	98.0	COG2771@1|root,COG2771@2|Bacteria,1MWC0@1224|Proteobacteria,1RSD4@1236|Gammaproteobacteria,1X4BS@135614|Xanthomonadales	135614|Xanthomonadales	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
REGS1_k127_8574290_7	292415.Tbd_1111	8.37e-10	64.0	2E445@1|root,32Z0E@2|Bacteria,1N7FY@1224|Proteobacteria,2VWT7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8574290_2	1163617.SCD_n00731	9.569e-113	372.0	COG0457@1|root,COG0457@2|Bacteria,1QV5B@1224|Proteobacteria,2WGRP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2,TPR_16
REGS1_k127_8574290_5	1121935.AQXX01000101_gene676	2.806e-23	108.0	COG4625@1|root,COG4625@2|Bacteria,1RDX6@1224|Proteobacteria,1S53I@1236|Gammaproteobacteria,1XR4I@135619|Oceanospirillales	135619|Oceanospirillales	S	Autotransporter beta-domain	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
REGS1_k127_8574290_3	1485544.JQKP01000003_gene108	1.273e-92	310.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,44VHJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
REGS1_k127_8574290_1	580332.Slit_2038	1.289e-173	548.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,44V1W@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_8574290_4	522306.CAP2UW1_3923	3.93e-49	180.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,1KQ3X@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
REGS1_k127_8626507_3	580332.Slit_2759	6.379e-59	204.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,44V93@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	pilT	-	-	ko:K02669,ko:K12203	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2,3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
REGS1_k127_8626507_1	580332.Slit_2758	4.9e-103	340.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,44V25@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
REGS1_k127_8626507_0	580332.Slit_2757	1.611e-114	376.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,44V7F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
REGS1_k127_8626507_2	580332.Slit_2756	9.63e-83	278.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria,44VT3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
REGS1_k127_8626507_4	580332.Slit_1173	1.963e-06	51.0	28HEC@1|root,2Z7QS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8652528_8	1288494.EBAPG3_5360	6.295e-29	121.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,372FF@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
REGS1_k127_8652528_4	28229.ND2E_4233	4.604e-92	322.0	COG2199@1|root,COG4191@1|root,COG3706@2|Bacteria,COG4191@2|Bacteria,1MZV7@1224|Proteobacteria,1T23Z@1236|Gammaproteobacteria,2Q7N3@267889|Colwelliaceae	1236|Gammaproteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1,dCache_3
REGS1_k127_8652528_7	1123401.JHYQ01000014_gene811	2.861e-50	186.0	COG0727@1|root,COG0727@2|Bacteria,1RGTX@1224|Proteobacteria,1S6FY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
REGS1_k127_8652528_5	395494.Galf_1244	7.665e-89	301.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,44V2F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Spermine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_8652528_3	580332.Slit_2559	1.92e-97	320.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2VP8A@28216|Betaproteobacteria,44W9X@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	hyfI	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
REGS1_k127_8652528_1	580332.Slit_2560	4.691e-277	858.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,2VJ0R@28216|Betaproteobacteria,44W90@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 30 kDa subunit	hyfG	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
REGS1_k127_8652528_0	580332.Slit_2561	1.233e-286	883.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria,44W60@713636|Nitrosomonadales	28216|Betaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	hyfF	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
REGS1_k127_8652528_2	580332.Slit_2562	6.169e-104	341.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,2VJTI@28216|Betaproteobacteria,44W5S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase 4 membrane	hyfE	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
REGS1_k127_8652528_6	1454004.AW11_01545	2.913e-87	291.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,2VKBD@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADH dehydrogenase	hyfD	-	-	-	-	-	-	-	-	-	-	-	NADHdh
REGS1_k127_8666148_10	1121123.AUAO01000002_gene382	8.698e-08	55.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,2KFGH@204458|Caulobacterales	204458|Caulobacterales	T	TIGRFAM diguanylate cyclase	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
REGS1_k127_8666148_7	580332.Slit_0171	1.925e-82	276.0	COG2731@1|root,COG2731@2|Bacteria,1RJ5F@1224|Proteobacteria,2VTSG@28216|Betaproteobacteria,44VXN@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
REGS1_k127_8666148_4	580332.Slit_0169	1.823e-172	542.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,44VEK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
REGS1_k127_8666148_6	1485544.JQKP01000002_gene1396	2.483e-121	393.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,44VK9@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_8666148_3	580332.Slit_0167	2.711e-200	629.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,44V36@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
REGS1_k127_8666148_8	580332.Slit_0166	1.676e-65	230.0	COG3663@1|root,COG3663@2|Bacteria,1REPV@1224|Proteobacteria,2VRAT@28216|Betaproteobacteria,44WHS@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Uracil DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_8666148_9	551789.ATVJ01000001_gene2570	3.423e-40	166.0	2FAR1@1|root,342YE@2|Bacteria,1NXK0@1224|Proteobacteria,2UT7M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PIN_4
REGS1_k127_8666148_1	580332.Slit_0165	2.455e-241	748.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,44V0A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
REGS1_k127_8666148_0	580332.Slit_0164	1.686e-268	840.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,44VGW@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Soluble lytic murein transglycosylase L domain	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
REGS1_k127_8666148_2	580332.Slit_2672	7.808e-204	638.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,44V7W@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
REGS1_k127_8666148_5	580332.Slit_1672	1.619e-132	425.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,44V38@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
REGS1_k127_874561_4	580332.Slit_1062	6.992e-44	162.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,44V46@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
REGS1_k127_874561_0	580332.Slit_1061	0.0	1127.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,44VHK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
REGS1_k127_874561_1	580332.Slit_1060	1.404e-116	377.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,44UZM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
REGS1_k127_874561_3	580332.Slit_1059	1.347e-48	177.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,44VYX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	CRS1_YhbY	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
REGS1_k127_874561_2	580332.Slit_1058	1.648e-61	213.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,44VQE@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_8806162_0	580332.Slit_0311	1.34e-306	953.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,44V3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
REGS1_k127_8806162_3	580332.Slit_0313	1.956e-63	219.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,44VX5@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
REGS1_k127_8806162_1	580332.Slit_0312	3.179e-199	628.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_8806162_2	1485544.JQKP01000011_gene765	1.699e-64	223.0	COG0859@1|root,COG0859@2|Bacteria,1PRP7@1224|Proteobacteria,2VMYH@28216|Betaproteobacteria,44VET@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
REGS1_k127_8916109_9	1123487.KB892835_gene3571	6.34e-17	82.0	COG4580@1|root,COG4580@2|Bacteria,1MX77@1224|Proteobacteria,2VNI7@28216|Betaproteobacteria,2KXGT@206389|Rhodocyclales	28216|Betaproteobacteria	G	LamB porin	-	-	-	-	-	-	-	-	-	-	-	-	LamB
REGS1_k127_8916109_4	1265502.KB905930_gene1526	8.079e-144	464.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2VGZM@28216|Betaproteobacteria,4AD80@80864|Comamonadaceae	28216|Betaproteobacteria	P	TOBE domain	-	-	-	ko:K10111	ko02010,map02010	M00194,M00200,M00204,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
REGS1_k127_8916109_1	1265502.KB905930_gene1525	1.066e-182	578.0	COG2182@1|root,COG2182@2|Bacteria,1N9AE@1224|Proteobacteria,2VMD1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein	malE	-	-	ko:K10108	ko02010,ko02030,map02010,map02030	M00194	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22	-	-	SBP_bac_8
REGS1_k127_8916109_2	1265502.KB905930_gene1524	2.739e-182	585.0	COG1175@1|root,COG1175@2|Bacteria,1MXKR@1224|Proteobacteria,2VIPP@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Maltose transport system permease protein MalF P2 domain	malF	-	-	ko:K10109	ko02010,map02010	M00194	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22	-	-	BPD_transp_1,MalF_P2
REGS1_k127_8916109_5	29581.BW37_04586	1.832e-139	448.0	COG3833@1|root,COG3833@2|Bacteria,1QA3Z@1224|Proteobacteria,2VN8B@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	malG	-	-	ko:K10110	ko02010,map02010	M00194	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.1,3.A.1.1.22	-	-	BPD_transp_1
REGS1_k127_8916109_7	1265502.KB905930_gene1522	1.814e-33	134.0	COG1523@1|root,COG1523@2|Bacteria,1NFW8@1224|Proteobacteria,2VXFE@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial pullanase-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	PUD
REGS1_k127_8916109_0	1120999.JONM01000013_gene2201	2.476e-268	835.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,2VHF6@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Alpha amylase, catalytic domain	malS	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
REGS1_k127_8916109_6	926561.KB900623_gene885	4.544e-96	322.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia	186801|Clostridia	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_8916109_3	861299.J421_4127	5.616e-182	584.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	-	-	3.2.1.1,3.2.1.41	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	-	R02108,R02111,R02112,R11262	-	ko00000,ko00001,ko01000	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM26,CBM_20,CBM_25,CBM_48,PUD
REGS1_k127_8916109_8	1123487.KB892840_gene8	5.792e-21	102.0	2D1A4@1|root,32XQB@2|Bacteria,1N5B0@1224|Proteobacteria,2VV8M@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
REGS1_k127_8918452_7	1485544.JQKP01000001_gene1021	9.869e-27	113.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,44VTD@713636|Nitrosomonadales	28216|Betaproteobacteria	V	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
REGS1_k127_8918452_3	580332.Slit_2633	4.623e-219	686.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,44VDT@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM sigma-54 factor interaction domain-containing protein	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_8918452_1	580332.Slit_2634	1.766e-245	770.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,2WHEY@28216|Betaproteobacteria,44V0X@713636|Nitrosomonadales	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
REGS1_k127_8918452_8	580332.Slit_2635	2.421e-20	93.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,44W3C@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_8918452_9	224911.27350827	0.0001548	46.0	2F0SV@1|root,33TUX@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8918452_4	580332.Slit_0321	4.545e-180	566.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,44V15@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Polyprenyl synthetase	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_8918452_2	580332.Slit_0320	8.458e-226	704.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VIPI@28216|Betaproteobacteria,44WDF@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	proP	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_8918452_6	580332.Slit_0319	5.091e-32	136.0	2ETRW@1|root,33M9C@2|Bacteria,1NEBE@1224|Proteobacteria,2VXIY@28216|Betaproteobacteria,44W11@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8918452_5	580332.Slit_0318	8.651e-180	578.0	COG4692@1|root,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2VMXN@28216|Betaproteobacteria,44VCC@713636|Nitrosomonadales	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
REGS1_k127_8918452_0	580332.Slit_0317	3.968e-255	793.0	COG1807@1|root,COG1807@2|Bacteria,1R7N1@1224|Proteobacteria,2VPJR@28216|Betaproteobacteria,44V9W@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
REGS1_k127_8927691_3	1123487.KB892835_gene3571	3.776e-71	256.0	COG4580@1|root,COG4580@2|Bacteria,1MX77@1224|Proteobacteria,2VNI7@28216|Betaproteobacteria,2KXGT@206389|Rhodocyclales	28216|Betaproteobacteria	G	LamB porin	-	-	-	-	-	-	-	-	-	-	-	-	LamB
REGS1_k127_8927691_2	580332.Slit_0050	8.468e-121	395.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,44WHA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
REGS1_k127_8927691_0	580332.Slit_0049	1.728e-210	659.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,44V7V@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
REGS1_k127_8927691_1	580332.Slit_0048	1.201e-207	648.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,44VB9@713636|Nitrosomonadales	28216|Betaproteobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
REGS1_k127_8940078_2	580332.Slit_1750	1.978e-115	375.0	COG4181@1|root,COG4181@2|Bacteria,1MXG9@1224|Proteobacteria,2VI54@28216|Betaproteobacteria,44VF1@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ABC transporter	lolD	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_8940078_3	395494.Galf_0346	7.801e-23	105.0	COG0664@1|root,COG0664@2|Bacteria,1NBRS@1224|Proteobacteria,2WCFJ@28216|Betaproteobacteria,44VZA@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_8940078_0	686340.Metal_0607	0.0	1407.0	COG1111@1|root,COG4889@1|root,COG1111@2|Bacteria,COG4889@2|Bacteria,1QZFK@1224|Proteobacteria	1224|Proteobacteria	L	type iii restriction	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,Mrr_cat_2,N6_Mtase,ResIII
REGS1_k127_8940078_1	580332.Slit_1748	0.0	1211.0	COG3127@1|root,COG3127@2|Bacteria,1MU9R@1224|Proteobacteria,2VHHQ@28216|Betaproteobacteria,44VBM@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_9082143_10	580332.Slit_2629	4.361e-24	103.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
REGS1_k127_9082143_7	580332.Slit_0387	1.33e-103	338.0	COG5405@1|root,COG5405@2|Bacteria,1RAFD@1224|Proteobacteria,2VMEF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM 20S proteasome, A and B subunits	-	-	3.4.25.2	ko:K01419	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Proteasome
REGS1_k127_9082143_2	395494.Galf_0384	9.879e-170	544.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VP8B@28216|Betaproteobacteria,44VEG@713636|Nitrosomonadales	28216|Betaproteobacteria	EH	Anthranilate synthase component I domain protein	-	-	2.6.1.85	ko:K01665,ko:K13950	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind,GATase
REGS1_k127_9082143_0	580332.Slit_0398	0.0	1170.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,44V8Q@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
REGS1_k127_9082143_9	580332.Slit_0399	4.504e-32	125.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,44W31@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
REGS1_k127_9082143_8	395494.Galf_0389	5.308e-96	317.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,44VSD@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
REGS1_k127_9082143_4	580332.Slit_0401	2.524e-129	419.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,44VKK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
REGS1_k127_9082143_5	580332.Slit_0402	1.061e-127	413.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,44WCA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART protein phosphatase 2C domain protein	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
REGS1_k127_9082143_3	580332.Slit_0403	4.396e-132	424.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,44V1Y@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
REGS1_k127_9082143_6	580332.Slit_0404	6.548e-106	347.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,44VFE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
REGS1_k127_9082143_1	580332.Slit_0405	3.302e-182	574.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,44V6C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_9094885_1	580332.Slit_0895	1.06e-119	391.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ABC transporter, periplasmic molybdate-binding protein	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
REGS1_k127_9094885_0	85643.Tmz1t_2726	9.601e-144	462.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2VHDA@28216|Betaproteobacteria,2KVFY@206389|Rhodocyclales	206389|Rhodocyclales	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
REGS1_k127_9094885_2	580332.Slit_1337	1.802e-32	127.0	2E588@1|root,3300P@2|Bacteria,1N79I@1224|Proteobacteria,2W3RS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF5062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5062
REGS1_k127_9095211_6	580332.Slit_1848	3.632e-20	90.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,44V9V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9095211_8	28229.ND2E_4177	0.0003889	48.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal,PAS_3
REGS1_k127_9095211_7	261292.Nit79A3_2565	1.402e-08	57.0	COG1180@1|root,COG1180@2|Bacteria,1R8XY@1224|Proteobacteria,2WFUM@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_9095211_3	292415.Tbd_1586	1.227e-64	228.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
REGS1_k127_9095211_2	580332.Slit_1844	5.52e-125	404.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,44W5F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
REGS1_k127_9095211_1	1485544.JQKP01000014_gene1874	3.104e-187	588.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,44VIC@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
REGS1_k127_9095211_4	580332.Slit_1841	5.531e-58	203.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,44W0Z@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM succinate dehydrogenase, cytochrome b556 subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
REGS1_k127_9095211_5	261292.Nit79A3_2532	2.534e-32	134.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,373DV@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
REGS1_k127_9095211_0	580332.Slit_1839	3.739e-269	832.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,44V9G@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
## 2263 queries scanned
## Total time (seconds): 39.25232553482056
## Rate: 57.65 q/s