## Tue Nov 12 01:09:07 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/R/REGS1_bin.30.fa -m mmseqs --itype genome -o REGS1_bin.30 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/REGS1_bin.30 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
REGS1_k127_1023346_3	28564.XP_002477883.1	3.489e-17	97.0	KOG1218@1|root,KOG1218@2759|Eukaryota	2759|Eukaryota	S	negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	-	-	-	-	-	-	-	-	-	-	-	-	EB,TIL
REGS1_k127_1023346_1	1149133.ppKF707_1108	5.637e-84	293.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,1RMB8@1236|Gammaproteobacteria,1YDHD@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	RmuC family	rmuC	GO:0006139,GO:0006259,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
REGS1_k127_1023346_2	404589.Anae109_0551	2.829e-77	275.0	28JIP@1|root,2Z82C@2|Bacteria,1R5N9@1224|Proteobacteria	1224|Proteobacteria	S	s1 p1 nuclease	-	-	3.1.30.1	ko:K05986	-	-	-	-	ko00000,ko01000	-	-	-	S1-P1_nuclease
REGS1_k127_1023346_0	903818.KI912268_gene1912	5.467e-101	344.0	COG5373@1|root,COG5373@2|Bacteria,3Y2GV@57723|Acidobacteria	57723|Acidobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
REGS1_k127_105208_1	1121918.ARWE01000001_gene2332	4.125e-49	176.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_105208_2	404589.Anae109_1581	2.864e-37	157.0	COG0425@1|root,COG0425@2|Bacteria,1N08X@1224|Proteobacteria,42RUG@68525|delta/epsilon subdivisions,2WNNK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	yedF	-	-	-	-	-	-	-	-	-	-	-	DrsE,TusA
REGS1_k127_105208_0	404589.Anae109_0912	1.26e-115	380.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_1061110_7	1232410.KI421412_gene383	2.335e-72	251.0	COG0778@1|root,COG0778@2|Bacteria,1RECN@1224|Proteobacteria,43DS9@68525|delta/epsilon subdivisions,2WNXD@28221|Deltaproteobacteria,43TGM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_1061110_14	290397.Adeh_3781	2.584e-07	63.0	COG3047@1|root,COG3047@2|Bacteria,1QAKM@1224|Proteobacteria,4355Q@68525|delta/epsilon subdivisions,2WZGM@28221|Deltaproteobacteria,2Z23W@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1061110_11	1123392.AQWL01000007_gene1017	5.542e-24	105.0	COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria,1KRW7@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
REGS1_k127_1061110_10	395494.Galf_2212	8.358e-26	110.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,44WIE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
REGS1_k127_1061110_4	404589.Anae109_3151	3.186e-75	271.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2WQNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
REGS1_k127_1061110_5	1304885.AUEY01000017_gene3733	4.779e-75	260.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1N47P@1224|Proteobacteria,42W9J@68525|delta/epsilon subdivisions,2WSBM@28221|Deltaproteobacteria,2MKZR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
REGS1_k127_1061110_0	1242864.D187_005734	3.058e-169	541.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2WK2U@28221|Deltaproteobacteria,2YTUH@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
REGS1_k127_1061110_13	1552758.NC00_06870	7.318e-20	94.0	2EE71@1|root,3381J@2|Bacteria,1NAS3@1224|Proteobacteria,1SJHX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	gas vesicle protein	gvpU	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1061110_6	935863.AWZR01000007_gene259	1.095e-73	272.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1RMHZ@1236|Gammaproteobacteria,1X3XJ@135614|Xanthomonadales	1236|Gammaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm2	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_1061110_1	903818.KI912268_gene1347	1.943e-154	501.0	COG0516@1|root,COG0516@2|Bacteria,3Y2I9@57723|Acidobacteria	2|Bacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaC	-	1.1.1.205,1.7.1.7	ko:K00088,ko:K00364	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R01134,R08240	RC00143,RC00457,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iSB619.SA_RS06660	IMPDH
REGS1_k127_1061110_2	404589.Anae109_3105	8.91e-112	376.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,42YSA@68525|delta/epsilon subdivisions,2WTWN@28221|Deltaproteobacteria,2YUWQ@29|Myxococcales	28221|Deltaproteobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
REGS1_k127_1061110_9	290397.Adeh_3202	1.076e-26	117.0	COG5612@1|root,COG5612@2|Bacteria	2|Bacteria	S	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
REGS1_k127_1061110_3	404589.Anae109_4233	9.629e-98	336.0	COG1752@1|root,COG1752@2|Bacteria,1RCDG@1224|Proteobacteria,43963@68525|delta/epsilon subdivisions,2X4CS@28221|Deltaproteobacteria,2YYRY@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
REGS1_k127_1061110_8	1192034.CAP_1358	1.971e-28	132.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
REGS1_k127_1068885_14	404589.Anae109_2551	5.74e-29	117.0	COG0546@1|root,COG0546@2|Bacteria,1QX7M@1224|Proteobacteria,438Y4@68525|delta/epsilon subdivisions,2X43J@28221|Deltaproteobacteria,2YY61@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
REGS1_k127_1068885_6	290397.Adeh_1215	8.634e-103	343.0	COG2912@1|root,COG2912@2|Bacteria,1MVJQ@1224|Proteobacteria,43824@68525|delta/epsilon subdivisions,2X3C7@28221|Deltaproteobacteria,2YVD2@29|Myxococcales	28221|Deltaproteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
REGS1_k127_1068885_9	1173025.GEI7407_1936	4.594e-58	210.0	2DK0G@1|root,30823@2|Bacteria,1G5HE@1117|Cyanobacteria,1HB9D@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM DNA RNA tunnel of bacterial DNA dependent RNA polymerase	-	-	-	-	-	-	-	-	-	-	-	-	Arr-ms
REGS1_k127_1068885_5	671143.DAMO_2638	9.657e-129	424.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
REGS1_k127_1068885_8	1007103.AFHW01000160_gene3089	4.964e-87	305.0	COG1162@1|root,COG1162@2|Bacteria,1TP8Q@1239|Firmicutes,4H9PJ@91061|Bacilli,26R2G@186822|Paenibacillaceae	91061|Bacilli	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA_2	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
REGS1_k127_1068885_4	404589.Anae109_0566	5.73e-175	560.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,43BQR@68525|delta/epsilon subdivisions,2X71T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_1068885_11	1123393.KB891327_gene316	1.084e-43	165.0	2E5C5@1|root,33046@2|Bacteria,1NNAA@1224|Proteobacteria,2W6KD@28216|Betaproteobacteria,1KT4P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
REGS1_k127_1068885_16	639282.DEFDS_1872	4.266e-09	64.0	2CIAQ@1|root,2ZXJG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1068885_0	118163.Ple7327_1680	6.538e-252	813.0	COG0474@1|root,COG0474@2|Bacteria,1G2YA@1117|Cyanobacteria	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_1068885_7	404589.Anae109_2562	4.095e-90	300.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,42VQ3@68525|delta/epsilon subdivisions,2WT1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
REGS1_k127_1068885_1	404589.Anae109_2563	6.322e-240	773.0	COG1156@1|root,COG1156@2|Bacteria,1R4RB@1224|Proteobacteria,42PJC@68525|delta/epsilon subdivisions,2WJB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
REGS1_k127_1068885_3	304371.MCP_2290	9.757e-178	580.0	COG1155@1|root,arCOG00868@2157|Archaea,2XT8I@28890|Euryarchaeota,2NANC@224756|Methanomicrobia	224756|Methanomicrobia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit	atpA-2	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
REGS1_k127_1068885_13	290397.Adeh_1201	7.135e-33	143.0	COG1436@1|root,COG1436@2|Bacteria	2|Bacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
REGS1_k127_1068885_10	290397.Adeh_1200	2.951e-52	199.0	COG1527@1|root,COG1527@2|Bacteria	2|Bacteria	C	subunit (C	atpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
REGS1_k127_1068885_15	404589.Anae109_2568	2.146e-26	109.0	COG0636@1|root,COG0636@2|Bacteria,1N5D3@1224|Proteobacteria,438SF@68525|delta/epsilon subdivisions,2WY87@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM H transporting two-sector ATPase C subunit	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
REGS1_k127_1068885_2	290397.Adeh_1197	2.11e-187	599.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
REGS1_k127_1091224_2	290397.Adeh_2572	3.354e-28	115.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WNNV@28221|Deltaproteobacteria,2Z08H@29|Myxococcales	28221|Deltaproteobacteria	C	Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
REGS1_k127_1091224_0	864051.BurJ1DRAFT_3207	1.056e-84	300.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,2VQRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
REGS1_k127_1091224_1	351160.RRC2	3.107e-31	128.0	arCOG06069@1|root,arCOG06069@2157|Archaea	2157|Archaea	S	TIGRFAM C_GCAxxG_C_C family	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
REGS1_k127_1107949_1	404589.Anae109_3381	2.927e-159	505.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_1107949_0	290397.Adeh_1183	0.0	1507.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
REGS1_k127_1107949_2	290397.Adeh_1184	8.025e-113	375.0	COG0845@1|root,COG0845@2|Bacteria,1RI9S@1224|Proteobacteria,42PDM@68525|delta/epsilon subdivisions,2WMKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
REGS1_k127_1107949_3	290397.Adeh_1185	1.78e-55	205.0	COG1309@1|root,COG1309@2|Bacteria,1NH8I@1224|Proteobacteria,42XD4@68525|delta/epsilon subdivisions,2WT25@28221|Deltaproteobacteria,2Z235@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_1107949_4	404589.Anae109_2569	1.857e-08	63.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,42UWC@68525|delta/epsilon subdivisions,2X5C3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM V-type ATPase 116 kDa	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
REGS1_k127_1175061_4	290397.Adeh_3927	5.166e-94	316.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2YZDA@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_1175061_9	1242864.D187_010102	1.966e-33	145.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42R06@68525|delta/epsilon subdivisions,2X1UD@28221|Deltaproteobacteria,2YZ3C@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
REGS1_k127_1175061_3	290397.Adeh_0471	1.921e-99	330.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KO	TIGRFAM Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
REGS1_k127_1175061_8	404589.Anae109_0514	1.06e-37	153.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
REGS1_k127_1175061_2	404589.Anae109_0515	6.677e-170	538.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2WJ8B@28221|Deltaproteobacteria,2YTZM@29|Myxococcales	28221|Deltaproteobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
REGS1_k127_1175061_1	404589.Anae109_0516	3.5e-176	562.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,2YTV5@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the HypD family	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
REGS1_k127_1175061_6	290397.Adeh_0475	6.108e-46	170.0	COG0298@1|root,COG0298@2|Bacteria	2|Bacteria	O	carbon dioxide binding	hypC	-	-	ko:K04653,ko:K04654	-	-	-	-	ko00000	-	-	-	HupF_HypC
REGS1_k127_1175061_5	290397.Adeh_0477	6.018e-56	200.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
REGS1_k127_1175061_0	290397.Adeh_0478	1.451e-295	914.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hybL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
REGS1_k127_1175061_7	290397.Adeh_0481	8.453e-46	168.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	hybS	-	1.12.2.1,1.12.99.6	ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
REGS1_k127_1190056_3	290397.Adeh_1896	2.925e-174	553.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
REGS1_k127_1190056_0	404589.Anae109_1963	2.861e-295	917.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,42PQK@68525|delta/epsilon subdivisions,2WJCT@28221|Deltaproteobacteria,2YUHK@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_1190056_10	502025.Hoch_2411	3.99e-18	95.0	2BB4A@1|root,324KN@2|Bacteria,1QAPV@1224|Proteobacteria,4357V@68525|delta/epsilon subdivisions,2X96M@28221|Deltaproteobacteria,2Z28J@29|Myxococcales	502025.Hoch_2411|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1190056_8	290397.Adeh_1899	4.721e-52	199.0	2DM7I@1|root,32UGD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1190056_4	398767.Glov_2511	9.338e-149	480.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
REGS1_k127_1190056_6	290397.Adeh_1901	1.928e-131	430.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_1190056_9	290397.Adeh_1902	3.368e-42	156.0	2CDR8@1|root,32ZSF@2|Bacteria,1NCBG@1224|Proteobacteria,42V4S@68525|delta/epsilon subdivisions,2WSDP@28221|Deltaproteobacteria,2YVN6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1190056_7	404589.Anae109_1956	1.301e-58	213.0	COG0484@1|root,COG1426@1|root,COG0484@2|Bacteria,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,HTH_25,TPR_14
REGS1_k127_1190056_5	290397.Adeh_1904	2.667e-147	508.0	COG0455@1|root,COG0455@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2YUZU@29|Myxococcales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
REGS1_k127_1190056_2	290397.Adeh_1906	7.288e-187	609.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,2YV6T@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_19,TPR_6,TPR_8
REGS1_k127_1190056_1	404589.Anae109_1952	1.281e-203	674.0	COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria,2YU4V@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
REGS1_k127_1214000_2	404589.Anae109_1472	6.955e-224	700.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YZR7@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
REGS1_k127_1214000_5	404589.Anae109_1471	3.432e-119	393.0	COG0457@1|root,COG0457@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,Zincin_1
REGS1_k127_1214000_11	682795.AciX8_1418	4.921e-05	55.0	COG1409@1|root,COG1409@2|Bacteria,3Y79E@57723|Acidobacteria,2JM0F@204432|Acidobacteriia	2|Bacteria	S	PFAM Calcineurin-like phosphoesterase	phoA	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos
REGS1_k127_1214000_6	1125863.JAFN01000001_gene1758	5.326e-103	355.0	COG2055@1|root,COG2055@2|Bacteria,1MWQY@1224|Proteobacteria,42SXH@68525|delta/epsilon subdivisions,2WP5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the LDH2 MDH2 oxidoreductase family	-	-	1.1.1.338	ko:K16844	ko00270,ko01120,map00270,map01120	-	R07137	RC00031	ko00000,ko00001,ko01000	-	-	-	Ldh_2
REGS1_k127_1214000_4	1122222.AXWR01000035_gene220	2.365e-130	423.0	COG0205@1|root,COG0205@2|Bacteria,1WM4B@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
REGS1_k127_1214000_0	290397.Adeh_2407	0.0	1156.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2YYKK@29|Myxococcales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_1214000_8	927658.AJUM01000037_gene2328	2.417e-70	252.0	COG3568@1|root,COG3568@2|Bacteria,4NV25@976|Bacteroidetes,2G248@200643|Bacteroidia,3XJNK@558415|Marinilabiliaceae	976|Bacteroidetes	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
REGS1_k127_1214000_7	290397.Adeh_2409	1.936e-83	291.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,2YVKY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
REGS1_k127_1214000_9	404589.Anae109_1463	8.397e-50	189.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
REGS1_k127_1214000_3	290397.Adeh_2411	5.031e-205	646.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2YUIN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
REGS1_k127_1214000_10	237727.NAP1_06320	6.17e-06	59.0	COG3063@1|root,COG3063@2|Bacteria,1N921@1224|Proteobacteria,2UHY2@28211|Alphaproteobacteria,2KE97@204457|Sphingomonadales	204457|Sphingomonadales	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16
REGS1_k127_1214000_1	290397.Adeh_2422	4.389e-245	768.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2WK5H@28221|Deltaproteobacteria,2YTYQ@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
REGS1_k127_1230775_1	290397.Adeh_0601	1.202e-84	309.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,2YX13@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR2	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
REGS1_k127_1230775_0	215803.DB30_8016	5.506e-156	512.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42Y7C@68525|delta/epsilon subdivisions,2WTJH@28221|Deltaproteobacteria,2YXEJ@29|Myxococcales	28221|Deltaproteobacteria	NT	Chemotaxis protein histidine kinase and related kinases	cheA2	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
REGS1_k127_1230775_3	290397.Adeh_0604	5.573e-57	213.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,42THA@68525|delta/epsilon subdivisions,2WNG6@28221|Deltaproteobacteria,2Z32W@29|Myxococcales	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
REGS1_k127_1230775_2	290397.Adeh_0605	1.586e-63	224.0	COG2203@1|root,COG2203@2|Bacteria,1P3F7@1224|Proteobacteria,4318K@68525|delta/epsilon subdivisions,2WWQB@28221|Deltaproteobacteria,2Z23F@29|Myxococcales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2
REGS1_k127_1246790_3	500632.CLONEX_04113	3.223e-05	51.0	COG4640@1|root,COG4640@2|Bacteria,1VEU9@1239|Firmicutes,24S06@186801|Clostridia	186801|Clostridia	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
REGS1_k127_1246790_4	500632.CLONEX_04113	0.0001189	50.0	COG4640@1|root,COG4640@2|Bacteria,1VEU9@1239|Firmicutes,24S06@186801|Clostridia	186801|Clostridia	S	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
REGS1_k127_1246790_2	290397.Adeh_1620	5.931e-59	205.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2YV05@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
REGS1_k127_1263472_0	404589.Anae109_3694	7.298e-149	491.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
REGS1_k127_1263472_1	404589.Anae109_3693	1.08e-122	403.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,42T8M@68525|delta/epsilon subdivisions,2WPBS@28221|Deltaproteobacteria,2Z198@29|Myxococcales	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	agmH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
REGS1_k127_1263472_2	1242864.D187_002807	1.044e-33	133.0	COG1664@1|root,COG1664@2|Bacteria,1ND4H@1224|Proteobacteria	1224|Proteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_128351_0	1125863.JAFN01000001_gene2272	3.497e-09	69.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
REGS1_k127_1292825_1	404589.Anae109_1357	5.369e-175	566.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJ30@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
REGS1_k127_1292825_5	243231.GSU2635	4.882e-19	102.0	COG2703@1|root,COG2703@2|Bacteria,1N8CS@1224|Proteobacteria,42VDH@68525|delta/epsilon subdivisions,2WRTV@28221|Deltaproteobacteria,43VEP@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_1292825_4	290397.Adeh_2162	6.079e-86	294.0	COG0500@1|root,COG2226@2|Bacteria,1MXDY@1224|Proteobacteria,437FY@68525|delta/epsilon subdivisions,2X2NJ@28221|Deltaproteobacteria,2Z076@29|Myxococcales	28221|Deltaproteobacteria	H	methyltransferase	-	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	-
REGS1_k127_1292825_0	290397.Adeh_2513	9.726e-250	803.0	COG3857@1|root,COG3857@2|Bacteria	2|Bacteria	L	exonuclease activity	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
REGS1_k127_1292825_6	1297742.A176_07375	2.603e-15	87.0	COG4932@1|root,COG4932@2|Bacteria,1PEGG@1224|Proteobacteria,43854@68525|delta/epsilon subdivisions,2X3F3@28221|Deltaproteobacteria,2YVTB@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
REGS1_k127_1292825_2	290397.Adeh_2848	9.606e-112	371.0	COG0354@1|root,COG0354@2|Bacteria,1QYGE@1224|Proteobacteria,43CCJ@68525|delta/epsilon subdivisions,2WYDB@28221|Deltaproteobacteria,2Z3H2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
REGS1_k127_1292825_3	880073.Calab_1764	2.052e-109	372.0	COG4191@1|root,COG4191@2|Bacteria,2NP93@2323|unclassified Bacteria	2|Bacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_1307222_1	404589.Anae109_3858	1.02e-137	448.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_1307222_5	290397.Adeh_3741	5.621e-38	153.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
REGS1_k127_1307222_3	404589.Anae109_3860	1.529e-122	397.0	COG1024@1|root,COG1024@2|Bacteria,1MXBB@1224|Proteobacteria,43AM0@68525|delta/epsilon subdivisions,2X615@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.1.1.41	ko:K11264	ko00640,map00640	-	R00923	RC00097	ko00000,ko00001,ko01000	-	-	-	ECH_1
REGS1_k127_1307222_4	290397.Adeh_3745	5.485e-90	309.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_1307222_6	1323663.AROI01000020_gene663	1.549e-08	64.0	2DQ04@1|root,33466@2|Bacteria,1NA4M@1224|Proteobacteria,1SEGC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1307222_0	1278073.MYSTI_06050	2.413e-158	518.0	COG2303@1|root,COG2303@2|Bacteria,1P9UF@1224|Proteobacteria,43A4M@68525|delta/epsilon subdivisions,2WYKE@28221|Deltaproteobacteria,2Z0NN@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
REGS1_k127_1307222_2	404589.Anae109_3865	1.645e-126	408.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_131273_0	404589.Anae109_0690	1.755e-245	765.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
REGS1_k127_1314296_5	443143.GM18_0604	1.158e-27	117.0	COG4393@1|root,COG4393@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
REGS1_k127_1314296_2	290397.Adeh_1997	8.706e-100	347.0	COG2197@1|root,COG2197@2|Bacteria,1R9GN@1224|Proteobacteria,42PU2@68525|delta/epsilon subdivisions,2X60T@28221|Deltaproteobacteria,2Z327@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_1314296_0	290397.Adeh_1998	8.291e-193	629.0	COG4585@1|root,COG4585@2|Bacteria,1N0JE@1224|Proteobacteria,42UG3@68525|delta/epsilon subdivisions,2WQFT@28221|Deltaproteobacteria,2Z1DF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3
REGS1_k127_1314296_1	404589.Anae109_1807	1.83e-114	379.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48,Peptidase_M56
REGS1_k127_1314296_4	246194.CHY_0355	8.992e-28	117.0	COG2864@1|root,COG2864@2|Bacteria,1V1XF@1239|Firmicutes,24GTD@186801|Clostridia	186801|Clostridia	C	PFAM Cytochrome b(N-terminal) b6 petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_1359028_3	279714.FuraDRAFT_1796	7.784e-64	224.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,2VQ72@28216|Betaproteobacteria,2KR4M@206351|Neisseriales	206351|Neisseriales	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
REGS1_k127_1359028_0	1192034.CAP_6024	0.0	1137.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,42NGX@68525|delta/epsilon subdivisions,2WJC0@28221|Deltaproteobacteria,2YWXY@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434	E1-E2_ATPase,Hydrolase
REGS1_k127_1359028_1	1192034.CAP_6025	1.056e-279	870.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,42NCD@68525|delta/epsilon subdivisions,2WJ03@28221|Deltaproteobacteria,2YWFC@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
REGS1_k127_1359028_2	404589.Anae109_3864	4.51e-100	332.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,42S4A@68525|delta/epsilon subdivisions,2WNE7@28221|Deltaproteobacteria,2Z30E@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
REGS1_k127_1359028_4	448385.sce5213	3.308e-07	63.0	COG3047@1|root,COG3047@2|Bacteria,1QAKM@1224|Proteobacteria,4355Q@68525|delta/epsilon subdivisions,2WZGM@28221|Deltaproteobacteria,2Z23W@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1373993_2	671143.DAMO_2737	1.759e-45	173.0	28IJY@1|root,2Z8KS@2|Bacteria	2|Bacteria	S	CRISPR-associated protein GSU0053 (Cas_GSU0053)	-	-	-	ko:K19131	-	-	-	-	ko00000,ko02048	-	-	-	Cas_GSU0053
REGS1_k127_1373993_1	278957.ABEA03000104_gene348	9.153e-120	410.0	28JGZ@1|root,2Z9AI@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K19136	-	-	-	-	ko00000,ko02048	-	-	-	-
REGS1_k127_1373993_0	555779.Dthio_PD1459	2.804e-156	515.0	COG1203@1|root,COG1203@2|Bacteria,1R8FD@1224|Proteobacteria,42NNV@68525|delta/epsilon subdivisions,2WMHK@28221|Deltaproteobacteria,2MGDF@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	-	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,Helicase_C
REGS1_k127_137429_1	1439940.BAY1663_02741	1.289e-42	158.0	COG2963@1|root,COG2963@2|Bacteria,1N1AA@1224|Proteobacteria,1SAUG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Escherichia coli O157 H7 ortholog	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
REGS1_k127_137429_0	596154.Alide2_1764	1.129e-133	433.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,2VHER@28216|Betaproteobacteria,4AGKJ@80864|Comamonadaceae	28216|Betaproteobacteria	L	PFAM Integrase catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
REGS1_k127_1375620_1	1242864.D187_001908	7.916e-59	222.0	COG4249@1|root,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,Peptidase_C14
REGS1_k127_1375620_2	290397.Adeh_3148	1.943e-47	178.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_1375620_5	1121935.AQXX01000042_gene4588	4.424e-26	124.0	COG4733@1|root,COG4733@2|Bacteria,1R55I@1224|Proteobacteria,1S5X2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1375620_4	404589.Anae109_0273	4.661e-34	132.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_1375620_0	404589.Anae109_0274	3.171e-105	346.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,43AEV@68525|delta/epsilon subdivisions,2X5YA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
REGS1_k127_1394474_1	330214.NIDE3675	2.165e-62	223.0	2DKWD@1|root,30KRK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
REGS1_k127_1394474_0	330214.NIDE3676	6.569e-66	241.0	2DBP7@1|root,2ZA82@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1394474_2	1232410.KI421412_gene143	0.0003395	53.0	2DYHM@1|root,349SC@2|Bacteria,1PD5T@1224|Proteobacteria,43127@68525|delta/epsilon subdivisions,2WWK1@28221|Deltaproteobacteria,43VFD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
REGS1_k127_1394943_0	290397.Adeh_1593	0.0	1921.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2YUJI@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
REGS1_k127_1394943_2	290397.Adeh_1594	4.716e-123	398.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
REGS1_k127_1394943_8	290397.Adeh_1595	3.471e-26	117.0	COG1317@1|root,COG1317@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	fliH	-	-	ko:K02411,ko:K03223	ko02040,ko03070,map02040,map03070	M00332,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliH,HrpE,NolV
REGS1_k127_1394943_1	290397.Adeh_1596	1.511e-172	561.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,42M0K@68525|delta/epsilon subdivisions,2WISR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM H transporting two-sector ATPase alpha beta subunit central region	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
REGS1_k127_1394943_6	290397.Adeh_1598	2.261e-35	148.0	COG0745@1|root,COG0745@2|Bacteria	290397.Adeh_1598|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1394943_3	290397.Adeh_1601	1.515e-114	377.0	COG2313@1|root,COG2313@2|Bacteria,1MUQU@1224|Proteobacteria,42ZS4@68525|delta/epsilon subdivisions,2WV20@28221|Deltaproteobacteria,2YUUK@29|Myxococcales	28221|Deltaproteobacteria	Q	Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway	psuG	-	4.2.1.70	ko:K16329	ko00240,map00240	-	R01055	RC00432,RC00433	ko00000,ko00001,ko01000	-	-	-	Indigoidine_A
REGS1_k127_1394943_4	404589.Anae109_2211	5.691e-106	365.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,2YVNW@29|Myxococcales	28221|Deltaproteobacteria	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
REGS1_k127_1394943_5	404589.Anae109_2210	1.258e-38	147.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria	1224|Proteobacteria	M	soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
REGS1_k127_139503_9	290397.Adeh_4307	5.637e-44	164.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
REGS1_k127_139503_3	404589.Anae109_4453	4.975e-88	302.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,2YW1G@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
REGS1_k127_139503_5	404589.Anae109_4454	8.865e-69	236.0	COG0848@1|root,COG0848@2|Bacteria,1QAS7@1224|Proteobacteria,43E3G@68525|delta/epsilon subdivisions,2WZKU@28221|Deltaproteobacteria,2Z2C1@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
REGS1_k127_139503_2	404589.Anae109_4455	8.295e-114	370.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,42TN7@68525|delta/epsilon subdivisions,2WQK7@28221|Deltaproteobacteria,2Z366@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
REGS1_k127_139503_7	404589.Anae109_4457	7.308e-66	233.0	COG4191@1|root,COG4191@2|Bacteria,1R9SH@1224|Proteobacteria,42QAE@68525|delta/epsilon subdivisions,2WM61@28221|Deltaproteobacteria,2Z2WP@29|Myxococcales	28221|Deltaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,dCache_1
REGS1_k127_139503_4	404589.Anae109_4460	1.893e-75	283.0	COG1776@1|root,COG1776@2|Bacteria	2|Bacteria	NT	chemotaxis	cheC	GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918	-	ko:K03410	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheC
REGS1_k127_139503_1	215803.DB30_8730	1.16e-183	599.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1NW7P@1224|Proteobacteria,42PGY@68525|delta/epsilon subdivisions,2WM89@28221|Deltaproteobacteria,2YXV2@29|Myxococcales	28221|Deltaproteobacteria	NT	P2 response regulator binding domain	difE	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
REGS1_k127_139503_6	404589.Anae109_4462	1.586e-66	231.0	COG2201@1|root,COG2201@2|Bacteria,1N5ZX@1224|Proteobacteria,42UU0@68525|delta/epsilon subdivisions,2WQAS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver domain	difD	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
REGS1_k127_139503_8	290397.Adeh_4318	3.412e-44	171.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	difC	-	-	ko:K02659,ko:K03408	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
REGS1_k127_139503_0	290397.Adeh_4319	7.873e-199	629.0	COG0840@1|root,COG0840@2|Bacteria,1RA20@1224|Proteobacteria,42QNV@68525|delta/epsilon subdivisions,2WMT1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
REGS1_k127_139503_10	404589.Anae109_4465	3.531e-20	94.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,2YVMB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
REGS1_k127_1409563_3	290397.Adeh_0847	1.592e-41	154.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,4331F@68525|delta/epsilon subdivisions,2WXKR@28221|Deltaproteobacteria,2YY54@29|Myxococcales	28221|Deltaproteobacteria	C	SUF system FeS assembly protein	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
REGS1_k127_1409563_1	290397.Adeh_0848	2.348e-63	223.0	COG2151@1|root,COG2151@2|Bacteria,1NAVI@1224|Proteobacteria,42U1H@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Iron-sulfur cluster assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
REGS1_k127_1409563_2	290397.Adeh_0849	1.599e-46	170.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	FHA,Yop-YscD_cpl
REGS1_k127_1409563_0	298653.Franean1_6327	9.907e-109	361.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4ETQ1@85013|Frankiales	201174|Actinobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_1411781_0	1120792.JAFV01000001_gene1018	1.686e-15	85.0	COG0526@1|root,COG0526@2|Bacteria,1PDVE@1224|Proteobacteria,2UDJR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CO	Thiol disulfide interchange protein	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
REGS1_k127_1459782_0	290397.Adeh_3878	0.0	1155.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42YWM@68525|delta/epsilon subdivisions,2WUQP@28221|Deltaproteobacteria,2YZTC@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
REGS1_k127_1459782_1	290397.Adeh_3877	4.225e-144	472.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QYGN@1224|Proteobacteria,43CCX@68525|delta/epsilon subdivisions,2WXED@28221|Deltaproteobacteria,2YZUY@29|Myxococcales	28221|Deltaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
REGS1_k127_1473685_1	404589.Anae109_2072	2.328e-200	627.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,2YUKG@29|Myxococcales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase ammonia chain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
REGS1_k127_1473685_4	404589.Anae109_2065	6.042e-75	254.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2YYUB@29|Myxococcales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_1473685_5	290397.Adeh_1733	9.441e-72	255.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WWMK@28221|Deltaproteobacteria,2Z2ZS@29|Myxococcales	28221|Deltaproteobacteria	L	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
REGS1_k127_1473685_2	404589.Anae109_2062	5.047e-112	371.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WMDZ@28221|Deltaproteobacteria,2YV35@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
REGS1_k127_1473685_0	290397.Adeh_1737	4.613e-311	979.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,42T02@68525|delta/epsilon subdivisions,2WPNU@28221|Deltaproteobacteria,2YUP3@29|Myxococcales	28221|Deltaproteobacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
REGS1_k127_1480389_0	292459.STH2286	2.931e-62	233.0	COG4584@1|root,COG4584@2|Bacteria,1UW0T@1239|Firmicutes,24AQA@186801|Clostridia	186801|Clostridia	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
REGS1_k127_1480389_1	986075.CathTA2_2389	1.673e-52	209.0	COG1484@1|root,COG1484@2|Bacteria,1TRWF@1239|Firmicutes,4HC07@91061|Bacilli	91061|Bacilli	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
REGS1_k127_1480841_4	290397.Adeh_3586	4.387e-51	184.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_1480841_3	589865.DaAHT2_0405	1.167e-79	276.0	COG3221@1|root,COG3221@2|Bacteria,1MXD8@1224|Proteobacteria,42UZB@68525|delta/epsilon subdivisions,2WQSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_1480841_1	272134.KB731324_gene3218	1.772e-129	451.0	COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,1H7V4@1150|Oscillatoriales	1117|Cyanobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MHYT,PAS,PAS_3,PAS_9
REGS1_k127_1480841_7	639282.DEFDS_1872	0.0004955	52.0	2CIAQ@1|root,2ZXJG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1480841_0	290397.Adeh_3588	1.392e-144	463.0	COG1484@1|root,COG1484@2|Bacteria	2|Bacteria	L	DNA-dependent DNA replication	dnaC	-	3.4.21.53	ko:K02315,ko:K04076	-	-	-	-	ko00000,ko01000,ko01002,ko03032	-	-	-	AAA,IstB_IS21,Lon_C
REGS1_k127_1480841_6	290397.Adeh_3590	1.764e-41	153.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria,2YW65@29|Myxococcales	28221|Deltaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
REGS1_k127_1480841_5	290397.Adeh_3593	2.903e-49	179.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
REGS1_k127_1498196_11	290397.Adeh_1515	4.312e-21	93.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,2Z2XF@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
REGS1_k127_1498196_4	404589.Anae109_2311	1.691e-167	531.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,2YU4X@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
REGS1_k127_1498196_6	404589.Anae109_2312	2.34e-124	409.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,42M7V@68525|delta/epsilon subdivisions,2WIUB@28221|Deltaproteobacteria,2YUX2@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
REGS1_k127_1498196_12	1049564.TevJSym_aj00090	9.801e-17	90.0	COG0526@1|root,COG0526@2|Bacteria,1MZ36@1224|Proteobacteria,1S8UU@1236|Gammaproteobacteria,1J6KV@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
REGS1_k127_1498196_2	290397.Adeh_1510	3.079e-216	683.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2YTVY@29|Myxococcales	28221|Deltaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
REGS1_k127_1498196_7	290397.Adeh_1509	5.902e-118	385.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2WJV9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the phosphatidylserine decarboxylase family	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
REGS1_k127_1498196_3	404589.Anae109_2320	9.661e-190	614.0	COG5316@1|root,COG5316@2|Bacteria,1N0IJ@1224|Proteobacteria,43BYT@68525|delta/epsilon subdivisions,2WMTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
REGS1_k127_1498196_9	404589.Anae109_2330	1.313e-56	221.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,42VU4@68525|delta/epsilon subdivisions,2WQBA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein family UPF0079, ATPase	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
REGS1_k127_1498196_1	404589.Anae109_2331	1.969e-224	708.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2YURF@29|Myxococcales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
REGS1_k127_1498196_10	290397.Adeh_1501	4.512e-45	167.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,2Z1VF@29|Myxococcales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
REGS1_k127_1498196_5	290397.Adeh_1500	6.893e-127	408.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2YVHT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
REGS1_k127_1498196_0	290397.Adeh_1499	1.139e-242	756.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,2YU3G@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_1498196_8	404589.Anae109_2337	1.693e-108	357.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
REGS1_k127_1558910_1	391625.PPSIR1_33354	7.011e-95	321.0	COG1028@1|root,COG1028@2|Bacteria,1REA0@1224|Proteobacteria	1224|Proteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_1558910_0	290397.Adeh_0365	7.792e-123	398.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2YVC9@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
REGS1_k127_1560326_2	404589.Anae109_0967	1.109e-225	706.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria,2Z3GW@29|Myxococcales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metY-1	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_1560326_0	404589.Anae109_0968	2.458e-283	881.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2YZ4W@29|Myxococcales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
REGS1_k127_1560326_4	1144275.COCOR_02836	8.642e-08	65.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_3,DUF4347,HemolysinCabind,Phosphoesterase,VCBS,fn3
REGS1_k127_1560326_1	404589.Anae109_3440	3.26e-249	777.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YUNQ@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_1576078_2	288000.BBta_5617	0.0007422	51.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,3JR8N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
REGS1_k127_1576078_0	1449069.JMLO01000050_gene2918	1.17e-37	149.0	COG0346@1|root,COG0346@2|Bacteria,2IK75@201174|Actinobacteria,4G0GX@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_1576078_1	1121106.JQKB01000016_gene5355	2.639e-25	112.0	2AJ2R@1|root,319M2@2|Bacteria,1RJXB@1224|Proteobacteria,2UA6I@28211|Alphaproteobacteria,2JY06@204441|Rhodospirillales	204441|Rhodospirillales	S	Conserved hypothetical protein (Lin0512_fam)	-	-	-	-	-	-	-	-	-	-	-	-	Lin0512_fam
REGS1_k127_1586752_3	290397.Adeh_0615	9.828e-125	425.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,43AKK@68525|delta/epsilon subdivisions,2X60J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16,TPR_19
REGS1_k127_1586752_2	290397.Adeh_0614	2.257e-151	510.0	COG2201@1|root,COG2201@2|Bacteria,1QBTV@1224|Proteobacteria,42Y53@68525|delta/epsilon subdivisions,2WTZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
REGS1_k127_1586752_0	378806.STAUR_4587	2.273e-197	640.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42QI6@68525|delta/epsilon subdivisions,2WKX0@28221|Deltaproteobacteria,2YY1F@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine Phosphotransfer domain	frzE	-	2.7.13.3	ko:K03407,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
REGS1_k127_1586752_1	404589.Anae109_0656	1.329e-177	569.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	frzCD	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal,dCache_3
REGS1_k127_1586752_5	404589.Anae109_0654	1.228e-77	264.0	COG0835@1|root,COG0835@2|Bacteria,1PBBT@1224|Proteobacteria	1224|Proteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_1586752_4	404589.Anae109_0653	1.211e-104	347.0	COG2199@1|root,COG3706@2|Bacteria,1P9YW@1224|Proteobacteria,433H2@68525|delta/epsilon subdivisions,2WXC9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_1602319_10	1173020.Cha6605_3372	2.239e-36	141.0	COG3548@1|root,COG3548@2|Bacteria,1G8WP@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF1211)	-	GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662	-	-	-	-	-	-	-	-	-	-	DUF1211
REGS1_k127_1602319_0	1244869.H261_06606	1.221e-313	996.0	COG1352@1|root,COG2201@1|root,COG2433@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2433@2|Bacteria,1NQTI@1224|Proteobacteria,2TRH8@28211|Alphaproteobacteria,2JQ72@204441|Rhodospirillales	204441|Rhodospirillales	NT	COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
REGS1_k127_1602319_7	640081.Dsui_2806	7.02e-71	267.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV5M@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
REGS1_k127_1602319_9	215803.DB30_0198	5.569e-41	162.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria,2YXSM@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
REGS1_k127_1602319_11	1267533.KB906740_gene184	2.728e-36	150.0	COG2227@1|root,COG2227@2|Bacteria,3Y8HG@57723|Acidobacteria,2JNJ7@204432|Acidobacteriia	204432|Acidobacteriia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
REGS1_k127_1602319_4	324602.Caur_3182	1.094e-151	494.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
REGS1_k127_1602319_12	1382359.JIAL01000001_gene2425	1.15e-28	130.0	COG0668@1|root,COG0668@2|Bacteria,3Y9BD@57723|Acidobacteria,2JP5U@204432|Acidobacteriia	204432|Acidobacteriia	M	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	TM_helix
REGS1_k127_1602319_6	404589.Anae109_2964	7.068e-88	308.0	COG0463@1|root,COG0463@2|Bacteria,1R547@1224|Proteobacteria,42PDC@68525|delta/epsilon subdivisions,2WKYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	glycosyl transferase family 2	-	-	2.4.1.268	ko:K21349	-	-	-	-	ko00000,ko01000	-	GT81	-	Glycos_transf_2
REGS1_k127_1602319_8	468059.AUHA01000006_gene2846	7.018e-42	171.0	COG1408@1|root,COG1408@2|Bacteria,4NKIS@976|Bacteroidetes	976|Bacteroidetes	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
REGS1_k127_1602319_3	404589.Anae109_3099	6.696e-187	591.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2WJBJ@28221|Deltaproteobacteria,2YUMX@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1034	Acetate_kinase
REGS1_k127_1602319_1	743720.Psefu_3377	1.866e-212	697.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria,1YXMS@136845|Pseudomonas putida group	1236|Gammaproteobacteria	C	belongs to the CobB CobQ family	pta	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006091,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008959,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017001,GO:0017144,GO:0018130,GO:0019413,GO:0019427,GO:0019438,GO:0019541,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046394,GO:0046395,GO:0046459,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070689,GO:0071616,GO:0071704,GO:0072329,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	iG2583_1286.G2583_2834,iYL1228.KPN_02688	AAA_26,DRTGG,PTA_PTB
REGS1_k127_1602319_5	1131812.JQMS01000001_gene1971	2.712e-91	307.0	COG1028@1|root,COG1028@2|Bacteria,4NGQY@976|Bacteroidetes,1HZ7N@117743|Flavobacteriia,2NTZG@237|Flavobacterium	976|Bacteroidetes	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
REGS1_k127_1602319_2	290397.Adeh_3044	1.21e-195	621.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2YU9C@29|Myxococcales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
REGS1_k127_1634282_1	1121346.KB899823_gene2347	1.23e-136	443.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,4H9TE@91061|Bacilli,26QVP@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	-	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
REGS1_k127_1634282_2	404589.Anae109_2665	4.547e-130	426.0	COG0657@1|root,COG0657@2|Bacteria,1MVRE@1224|Proteobacteria,42XSE@68525|delta/epsilon subdivisions,2WTGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Pectinacetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	PAE
REGS1_k127_1634282_3	215803.DB30_7132	1.249e-74	262.0	COG4850@1|root,COG4850@2|Bacteria,1NN5H@1224|Proteobacteria,42XIW@68525|delta/epsilon subdivisions,2WT89@28221|Deltaproteobacteria,2YZTJ@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
REGS1_k127_1634282_10	1041146.ATZB01000010_gene3963	4.673e-09	69.0	COG0454@1|root,COG0454@2|Bacteria,1QU4I@1224|Proteobacteria,2TU4A@28211|Alphaproteobacteria,4B93P@82115|Rhizobiaceae	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
REGS1_k127_1634282_0	404589.Anae109_0189	0.0	1541.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
REGS1_k127_1634282_6	391625.PPSIR1_28283	2.992e-56	224.0	COG0204@1|root,COG0204@2|Bacteria,1RF5A@1224|Proteobacteria,4300N@68525|delta/epsilon subdivisions,2WVIK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
REGS1_k127_1634282_4	1144275.COCOR_06403	1.363e-72	253.0	COG3384@1|root,COG3384@2|Bacteria,1RB6Z@1224|Proteobacteria,43ACS@68525|delta/epsilon subdivisions,2X5SK@28221|Deltaproteobacteria,2YXTW@29|Myxococcales	28221|Deltaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
REGS1_k127_1634282_5	290397.Adeh_3826	2.485e-68	237.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
REGS1_k127_1634282_9	330214.NIDE3905	6.429e-17	87.0	COG1814@1|root,COG1814@2|Bacteria	2|Bacteria	S	cellular manganese ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
REGS1_k127_1683642_0	404589.Anae109_0574	1.251e-189	606.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,2YUZ0@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx/GppA phosphatase family	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
REGS1_k127_1683642_1	1117318.PRUB_11996	1.018e-75	263.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,2Q397@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
REGS1_k127_1683642_3	1449353.JQMQ01000005_gene2819	3.433e-24	115.0	COG0494@1|root,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,2NJBK@228398|Streptacidiphilus	201174|Actinobacteria	L	NUDIX domain	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
REGS1_k127_1683642_4	222534.KB893719_gene1067	3.667e-13	75.0	COG0494@1|root,COG0494@2|Bacteria,2GNRV@201174|Actinobacteria,4EXC2@85013|Frankiales	201174|Actinobacteria	GL	NUDIX domain	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
REGS1_k127_1683642_2	861299.J421_3996	5.507e-57	225.0	COG2954@1|root,COG5607@1|root,COG2954@2|Bacteria,COG5607@2|Bacteria,1ZTYF@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
REGS1_k127_1683642_5	1340493.JNIF01000003_gene1925	1.232e-06	60.0	COG0855@1|root,COG0855@2|Bacteria,3Y2YI@57723|Acidobacteria	57723|Acidobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
REGS1_k127_1693712_4	448385.sce0211	2.435e-67	235.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,42PDX@68525|delta/epsilon subdivisions,2WKH4@28221|Deltaproteobacteria,2Z05J@29|Myxococcales	28221|Deltaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
REGS1_k127_1693712_5	926550.CLDAP_23850	2.833e-64	234.0	COG0079@1|root,COG1492@1|root,COG0079@2|Bacteria,COG1492@2|Bacteria,2G5PU@200795|Chloroflexi	200795|Chloroflexi	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
REGS1_k127_1693712_1	448385.sce0210	7.225e-179	590.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2WJ22@28221|Deltaproteobacteria,2YZHE@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Aminotran_1_2,CbiA,GATase_3,TP_methylase
REGS1_k127_1693712_8	1278073.MYSTI_00978	7.818e-43	175.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,42TXY@68525|delta/epsilon subdivisions,2WQ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
REGS1_k127_1693712_10	1278073.MYSTI_00977	4.034e-33	145.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,42SUD@68525|delta/epsilon subdivisions,2WP5H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Phosphoglycerate mutase	-	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
REGS1_k127_1693712_7	404589.Anae109_3557	2.252e-47	176.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	1.3.7.14,1.3.7.15	ko:K03088,ko:K11333	ko00860,ko01110,map00860,map01110	-	R09053,R09060	RC01008	ko00000,ko00001,ko01000,ko03021	-	-	-	Fer4_NifH,Glyco_hydro_cc,Laminin_G_3,Sigma70_r2,Sigma70_r4_2
REGS1_k127_1693712_3	404589.Anae109_4174	1.005e-96	334.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,43AQI@68525|delta/epsilon subdivisions,2X64F@28221|Deltaproteobacteria	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4384,PEGA,Pkinase,TPR_12
REGS1_k127_1693712_2	483219.LILAB_26365	1.726e-118	427.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
REGS1_k127_1693712_12	404589.Anae109_3900	2.737e-28	128.0	2EGEF@1|root,33A6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1693712_9	1125863.JAFN01000001_gene2324	1.347e-34	149.0	COG0729@1|root,COG0729@2|Bacteria	2|Bacteria	M	surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
REGS1_k127_1693712_11	690850.Desaf_1512	3.526e-29	117.0	COG1942@1|root,COG1942@2|Bacteria,1N6WW@1224|Proteobacteria,42V9V@68525|delta/epsilon subdivisions,2WRUI@28221|Deltaproteobacteria,2MD44@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	TIGRFAM 4-oxalocrotonate tautomerase	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
REGS1_k127_1693712_0	290397.Adeh_0008	4.744e-236	736.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2YUAI@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
REGS1_k127_1698796_2	404589.Anae109_0385	1.507e-146	474.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2YU3T@29|Myxococcales	28221|Deltaproteobacteria	G	pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_1698796_1	290397.Adeh_4045	9.155e-175	553.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
REGS1_k127_1698796_6	290397.Adeh_4046	6.455e-33	129.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,42VCF@68525|delta/epsilon subdivisions,2WRI6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
REGS1_k127_1698796_0	290397.Adeh_4049	4.807e-245	773.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
REGS1_k127_1698796_5	1122222.AXWR01000014_gene1245	4.412e-35	138.0	COG1970@1|root,COG1970@2|Bacteria,1WK0I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
REGS1_k127_1702818_4	398767.Glov_1379	3.466e-18	83.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,43UBB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
REGS1_k127_1702818_2	483219.LILAB_04305	9.876e-84	295.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
REGS1_k127_1702818_1	404589.Anae109_3801	1.168e-200	642.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,2YV19@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
REGS1_k127_1702818_0	290397.Adeh_3676	1.513e-296	914.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2YU1K@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2638	PEPCK_C,PEPCK_N
REGS1_k127_1705494_0	290397.Adeh_3458	2.015e-77	276.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2Z262@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
REGS1_k127_1705494_1	404589.Anae109_3568	7.155e-41	153.0	2E4KV@1|root,32ZFU@2|Bacteria,1NPD5@1224|Proteobacteria,42XQS@68525|delta/epsilon subdivisions,2WTAP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3467)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3467
REGS1_k127_1705494_2	404589.Anae109_3571	3.262e-27	119.0	COG1555@1|root,COG1555@2|Bacteria	2|Bacteria	L	photosystem II stabilization	comEA	-	2.4.1.21	ko:K00703,ko:K02237,ko:K02238	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00429,M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko02044	3.A.11.1,3.A.11.2	GT5	-	HHH_3,PLDc_2,SLBB
REGS1_k127_1705494_4	1120999.JONM01000008_gene2093	9.306e-05	56.0	COG5184@1|root,COG5184@2|Bacteria,1QXVA@1224|Proteobacteria	1224|Proteobacteria	DZ	IPT/TIG domain	-	-	-	-	-	-	-	-	-	-	-	-	RHS_repeat,TIG
REGS1_k127_1714999_0	215803.DB30_7610	0.0	1116.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
REGS1_k127_1734629_7	290397.Adeh_2157	6.336e-19	86.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YUEB@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_1734629_6	944435.AXAJ01000005_gene3655	3.084e-20	102.0	2CJCI@1|root,32VQ7@2|Bacteria,1N0T9@1224|Proteobacteria,2VVIE@28216|Betaproteobacteria,1K176@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1734629_0	404589.Anae109_0266	1.763e-208	677.0	COG0745@1|root,COG1196@1|root,COG0745@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	ko:K02557,ko:K03497	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035,ko03000,ko03036,ko04812	1.A.30.1	-	-	OmpA
REGS1_k127_1734629_1	290397.Adeh_0246	2.912e-124	403.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2WIVV@28221|Deltaproteobacteria,2Z2ZT@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
REGS1_k127_1734629_2	290397.Adeh_0247	1.781e-73	271.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,42R1A@68525|delta/epsilon subdivisions,2WMV6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
REGS1_k127_1734629_3	1242864.D187_004487	5.184e-53	192.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2Z0B0@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
REGS1_k127_1734629_5	883.DvMF_0806	1.052e-36	146.0	COG2207@1|root,COG2207@2|Bacteria,1QKC9@1224|Proteobacteria,42TIX@68525|delta/epsilon subdivisions,2WR22@28221|Deltaproteobacteria,2MB6S@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
REGS1_k127_175977_0	330214.NIDE2097	2.105e-109	372.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,3J0RD@40117|Nitrospirae	40117|Nitrospirae	H	protein methyltransferase activity	-	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	TP_methylase
REGS1_k127_175977_1	1254432.SCE1572_02075	8.574e-44	178.0	COG2082@1|root,COG2082@2|Bacteria,1MX1E@1224|Proteobacteria,42RIY@68525|delta/epsilon subdivisions,2WN0J@28221|Deltaproteobacteria,2YWW3@29|Myxococcales	28221|Deltaproteobacteria	H	Precorrin-8X methylmutase	cbiC	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
REGS1_k127_1764476_0	290397.Adeh_1221	6.894e-254	796.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
REGS1_k127_176482_0	215803.DB30_5662	3.136e-122	405.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,42NN7@68525|delta/epsilon subdivisions,2WJG7@28221|Deltaproteobacteria,2YUAP@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
REGS1_k127_176482_1	1144275.COCOR_02606	8.119e-41	152.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria,2YV5C@29|Myxococcales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
REGS1_k127_1782283_3	1038860.AXAP01000047_gene1017	7.862e-08	67.0	COG2931@1|root,COG4932@1|root,COG2931@2|Bacteria,COG4932@2|Bacteria,1MU7T@1224|Proteobacteria,2U0ME@28211|Alphaproteobacteria,3JW85@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	PQ	COG2931, RTX toxins and related Ca2 -binding proteins	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF4347,FG-GAP,Polysacc_lyase,W_rich_C
REGS1_k127_1782283_1	1278073.MYSTI_06788	1.371e-40	175.0	COG0402@1|root,COG1506@1|root,COG4447@1|root,COG4932@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,COG4447@2|Bacteria,COG4932@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
REGS1_k127_1782283_2	243090.RB2440	3.819e-09	71.0	COG2133@1|root,COG2133@2|Bacteria,2J14W@203682|Planctomycetes	203682|Planctomycetes	G	Glucose / Sorbosone dehydrogenase	-	-	-	ko:K21430	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,Calx-beta,DUF4347,GSDH,Lectin_legB
REGS1_k127_1782283_4	1297742.A176_01922	0.0009016	53.0	COG3266@1|root,COG3386@1|root,COG3266@2|Bacteria,COG3386@2|Bacteria,1QXUY@1224|Proteobacteria,43C7M@68525|delta/epsilon subdivisions,2X7HX@28221|Deltaproteobacteria,2Z10E@29|Myxococcales	28221|Deltaproteobacteria	E	Calcium-binding EGF domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,EGF_CA
REGS1_k127_1782283_0	1242864.D187_006668	1.682e-59	213.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,42TD5@68525|delta/epsilon subdivisions,2WP3U@28221|Deltaproteobacteria,2YZG5@29|Myxococcales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF5011,HYR,OMP_b-brl,OmpA,TSP_3
REGS1_k127_1787240_4	290397.Adeh_3945	5.197e-82	274.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2YV59@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
REGS1_k127_1787240_2	404589.Anae109_2906	6.305e-156	509.0	2F062@1|root,33T9N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1787240_5	404589.Anae109_2905	6.39e-55	214.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_1787240_0	404589.Anae109_2904	3.472e-305	963.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42M4Y@68525|delta/epsilon subdivisions,2WMHY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HD,HD_5,HisKA,Response_reg
REGS1_k127_1787240_1	290397.Adeh_3778	2.737e-187	592.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2YTTW@29|Myxococcales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
REGS1_k127_1787240_3	404589.Anae109_3893	1.075e-155	493.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
REGS1_k127_1791490_0	292459.STH886	8.544e-223	735.0	COG1201@1|root,COG1201@2|Bacteria,1UHYQ@1239|Firmicutes,25E79@186801|Clostridia	186801|Clostridia	L	DEAD DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
REGS1_k127_1791490_1	1223523.H340_28235	2.105e-16	90.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
REGS1_k127_1827747_1	290397.Adeh_0720	1.198e-155	502.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,2YUT2@29|Myxococcales	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
REGS1_k127_1827747_0	1297742.A176_04730	2.16e-233	744.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_1827747_3	290397.Adeh_0722	3.429e-84	287.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WSCV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
REGS1_k127_1827747_2	404589.Anae109_0764	5.888e-102	349.0	COG0328@1|root,COG0328@2|Bacteria,1MZD1@1224|Proteobacteria,42UI6@68525|delta/epsilon subdivisions,2WQSU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Ribonuclease H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
REGS1_k127_1827747_4	290397.Adeh_0311	1.954e-76	265.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,42MJV@68525|delta/epsilon subdivisions,2WMKH@28221|Deltaproteobacteria,2YV71@29|Myxococcales	28221|Deltaproteobacteria	E	Pfam:Methyltransf_26	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
REGS1_k127_1827747_5	404589.Anae109_4442	1.001e-57	205.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH
REGS1_k127_1828026_2	404589.Anae109_0329	3.236e-05	55.0	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,4340I@68525|delta/epsilon subdivisions,2X4FB@28221|Deltaproteobacteria,2Z047@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_1828026_1	290397.Adeh_0598	3.617e-35	140.0	COG0633@1|root,COG0633@2|Bacteria	2|Bacteria	C	Ferredoxin	fdx	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
REGS1_k127_1828026_0	404589.Anae109_0641	8.138e-135	433.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YUFN@29|Myxococcales	28221|Deltaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	-	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
REGS1_k127_185338_4	316067.Geob_3741	2.986e-53	216.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_185338_9	215803.DB30_5852	3.03e-16	94.0	COG3325@1|root,COG3391@1|root,COG4412@1|root,COG3325@2|Bacteria,COG3391@2|Bacteria,COG4412@2|Bacteria,1R3SG@1224|Proteobacteria,42SZZ@68525|delta/epsilon subdivisions,2WPD0@28221|Deltaproteobacteria,2YUKS@29|Myxococcales	28221|Deltaproteobacteria	E	Fungalysin metallopeptidase (M36)	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M36,REJ
REGS1_k127_185338_15	156578.ATW7_00515	9.901e-05	56.0	COG2931@1|root,COG3227@1|root,COG3266@1|root,COG2931@2|Bacteria,COG3227@2|Bacteria,COG3266@2|Bacteria,1P416@1224|Proteobacteria,1RR7I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Zinc metalloprotease (Elastase)	proA	GO:0005575,GO:0005576	3.4.24.25,3.4.24.26	ko:K01399,ko:K08604	ko01503,ko02024,ko05110,ko05111,map01503,map02024,map05110,map05111	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	FTP,PepSY,Peptidase_M4,Peptidase_M4_C
REGS1_k127_185338_12	1121920.AUAU01000024_gene2382	5.652e-07	63.0	COG3303@1|root,COG4733@1|root,COG3303@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	4.2.2.1	ko:K01727	-	-	-	-	ko00000,ko01000	-	PL8	-	Big_2,DUF285,HYR,Laminin_G_3,Lyase_8,Lyase_8_C,Lyase_8_N,Paired_CXXCH_1,SLH,fn3
REGS1_k127_185338_10	690850.Desaf_0428	1.057e-14	89.0	COG3266@1|root,COG3391@1|root,COG4870@1|root,COG3266@2|Bacteria,COG3391@2|Bacteria,COG4870@2|Bacteria,1NC9B@1224|Proteobacteria,42Z35@68525|delta/epsilon subdivisions,2WTVH@28221|Deltaproteobacteria,2MD34@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM Peptidase C1A, papain C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C1
REGS1_k127_185338_0	443143.GM18_0599	1.084e-219	692.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42MCH@68525|delta/epsilon subdivisions,2WJPZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_185338_3	596151.DesfrDRAFT_2459	1.817e-79	284.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_185338_7	443143.GM18_0616	6.991e-26	122.0	COG4346@1|root,COG4346@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT,PMT_2,PMT_4TMC
REGS1_k127_185338_1	290397.Adeh_2819	1.854e-97	347.0	COG1287@1|root,COG1287@2|Bacteria,1NYIS@1224|Proteobacteria,430I0@68525|delta/epsilon subdivisions,2WW3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
REGS1_k127_185338_6	929712.KI912613_gene1379	1.006e-41	171.0	COG0463@1|root,COG0463@2|Bacteria,2HG3W@201174|Actinobacteria,4CSN8@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_185338_13	314225.ELI_08325	7.316e-07	62.0	COG4346@1|root,COG4346@2|Bacteria,1QHX0@1224|Proteobacteria,2TVG5@28211|Alphaproteobacteria,2K03Y@204457|Sphingomonadales	204457|Sphingomonadales	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
REGS1_k127_185338_11	443144.GM21_3557	2.386e-09	69.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
REGS1_k127_185338_2	443144.GM21_3558	1.351e-80	280.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_185338_8	316067.Geob_0057	7.313e-26	123.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
REGS1_k127_1853470_3	404589.Anae109_0526	1.136e-149	481.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	hybS	-	1.12.2.1,1.12.99.6	ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
REGS1_k127_1853470_0	290397.Adeh_0486	0.0	1204.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1Q712@1224|Proteobacteria,433SV@68525|delta/epsilon subdivisions,2WYAY@28221|Deltaproteobacteria,2YXT0@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,Transglut_core
REGS1_k127_1853470_11	290397.Adeh_2058	1.037e-72	254.0	COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,42S7K@68525|delta/epsilon subdivisions,2WQI0@28221|Deltaproteobacteria,2YW7K@29|Myxococcales	28221|Deltaproteobacteria	S	DTW	-	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
REGS1_k127_1853470_10	1144275.COCOR_02212	2.288e-76	272.0	COG1234@1|root,COG1234@2|Bacteria,1RGTD@1224|Proteobacteria,42XDY@68525|delta/epsilon subdivisions,2WSS6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
REGS1_k127_1853470_14	404589.Anae109_4393	1.59e-26	115.0	COG4872@1|root,COG4872@2|Bacteria,1NF4D@1224|Proteobacteria,42XRT@68525|delta/epsilon subdivisions,2WXTA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
REGS1_k127_1853470_4	290397.Adeh_0503	1.338e-139	455.0	COG0642@1|root,COG2205@2|Bacteria	290397.Adeh_0503|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1853470_2	404589.Anae109_2379	8.27e-214	671.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_1853470_1	404589.Anae109_2593	5.616e-240	754.0	28K0F@1|root,2Z9QE@2|Bacteria,1R5C6@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c554 and c-prime	pccF	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
REGS1_k127_1853470_8	404589.Anae109_2595	7.631e-81	286.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,42QRV@68525|delta/epsilon subdivisions,2WMUE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_1853470_9	404589.Anae109_2596	1.711e-80	273.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,42URY@68525|delta/epsilon subdivisions,2WQYF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_1853470_5	404589.Anae109_1836	3.957e-114	396.0	COG3005@1|root,COG3005@2|Bacteria,1QYGG@1224|Proteobacteria,42NFU@68525|delta/epsilon subdivisions,2WKHN@28221|Deltaproteobacteria,2Z2AP@29|Myxococcales	28221|Deltaproteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_1853470_16	1121405.dsmv_3189	1.146e-25	119.0	COG1633@1|root,COG1633@2|Bacteria,1N54T@1224|Proteobacteria,42UVQ@68525|delta/epsilon subdivisions,2WQDG@28221|Deltaproteobacteria,2MKJN@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_1853470_6	1265505.ATUG01000001_gene4503	2.478e-97	331.0	COG1738@1|root,COG2199@1|root,COG1738@2|Bacteria,COG3706@2|Bacteria,1R2H3@1224|Proteobacteria,43DDN@68525|delta/epsilon subdivisions,2X8JF@28221|Deltaproteobacteria,2MI5V@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Membrane-associated sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	MASE3
REGS1_k127_1853470_13	290397.Adeh_2019	9.136e-35	140.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,43B6C@68525|delta/epsilon subdivisions,2WQY7@28221|Deltaproteobacteria,2Z2ZY@29|Myxococcales	28221|Deltaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
REGS1_k127_1853470_19	1089547.KB913013_gene3944	4.761e-06	53.0	COG1874@1|root,COG2911@1|root,COG3209@1|root,COG3656@1|root,COG1874@2|Bacteria,COG2911@2|Bacteria,COG3209@2|Bacteria,COG3656@2|Bacteria,4PKBQ@976|Bacteroidetes,47XXU@768503|Cytophagia	976|Bacteroidetes	M	SprB repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,SdrD_B,SprB
REGS1_k127_1878623_0	215803.DB30_4591	1.136e-180	587.0	COG5009@1|root,COG5009@2|Bacteria,1P2NY@1224|Proteobacteria,431XY@68525|delta/epsilon subdivisions,2WW86@28221|Deltaproteobacteria,2YYSF@29|Myxococcales	28221|Deltaproteobacteria	M	serine-type D-Ala-D-Ala carboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1878623_6	83406.HDN1F_14560	3.009e-35	139.0	COG2076@1|root,COG2076@2|Bacteria,1MZ54@1224|Proteobacteria,1S8SG@1236|Gammaproteobacteria,1J6RR@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	ko:K03297	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
REGS1_k127_1878623_7	33905.BTHE_1948	4.575e-35	140.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4D18P@85004|Bifidobacteriales	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
REGS1_k127_1878623_1	521674.Plim_2933	3.537e-157	506.0	COG0659@1|root,COG0659@2|Bacteria,2J2QM@203682|Planctomycetes	203682|Planctomycetes	P	Molybdate transporter of MFS superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_MOT1
REGS1_k127_1878623_4	1500257.JQNM01000005_gene2378	2.056e-35	142.0	COG3832@1|root,COG3832@2|Bacteria,1MZXG@1224|Proteobacteria,2UBQP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
REGS1_k127_1878623_2	215803.DB30_2824	5.408e-97	330.0	COG0697@1|root,COG0697@2|Bacteria,1N3FA@1224|Proteobacteria,42RW0@68525|delta/epsilon subdivisions,2WNEH@28221|Deltaproteobacteria,2YXRF@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_1878623_8	760142.Hipma_0398	1.565e-07	58.0	2APB3@1|root,31ED9@2|Bacteria,1P60F@1224|Proteobacteria,432R9@68525|delta/epsilon subdivisions,2WXG4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1878623_5	1137268.AZXF01000004_gene2224	2.938e-35	143.0	COG1309@1|root,COG1309@2|Bacteria,2HMJ5@201174|Actinobacteria,4EMVN@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_1878623_3	107635.AZUO01000001_gene2043	7.425e-56	203.0	COG2890@1|root,COG2890@2|Bacteria,1QW4Z@1224|Proteobacteria,2U65C@28211|Alphaproteobacteria,36ZBZ@31993|Methylocystaceae	28211|Alphaproteobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
REGS1_k127_189043_4	1242864.D187_010037	6.526e-23	102.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2WNWA@28221|Deltaproteobacteria,2YW6N@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_189043_2	313603.FB2170_11471	1.584e-30	136.0	arCOG14808@1|root,308PC@2|Bacteria,4NR4D@976|Bacteroidetes,1IJ0R@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
REGS1_k127_189043_3	1089547.KB913013_gene4018	8.402e-27	126.0	COG3025@1|root,COG3025@2|Bacteria,4NM6K@976|Bacteroidetes,47PAH@768503|Cytophagia	976|Bacteroidetes	S	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
REGS1_k127_189043_0	378806.STAUR_0675	3.309e-105	366.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,42QGZ@68525|delta/epsilon subdivisions,2WKE6@28221|Deltaproteobacteria,2YYP7@29|Myxococcales	28221|Deltaproteobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
REGS1_k127_189043_1	1254432.SCE1572_14990	9.892e-44	164.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,2YV07@29|Myxococcales	28221|Deltaproteobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
REGS1_k127_1927275_7	382464.ABSI01000010_gene3895	5.243e-05	51.0	COG3049@1|root,COG3049@2|Bacteria	2|Bacteria	M	Linear amide C-N hydrolases, choloylglycine hydrolase family	-	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
REGS1_k127_1927275_0	391625.PPSIR1_25966	1.973e-78	274.0	COG2207@1|root,COG2207@2|Bacteria,1MX23@1224|Proteobacteria,42UHJ@68525|delta/epsilon subdivisions,2WT4S@28221|Deltaproteobacteria,2YUXZ@29|Myxococcales	28221|Deltaproteobacteria	K	Arabinose-binding domain of AraC transcription regulator, N-term	oruR2	-	-	-	-	-	-	-	-	-	-	-	Arabinose_bd,HTH_18
REGS1_k127_1927275_1	290397.Adeh_2296	1.233e-66	249.0	COG3797@1|root,COG3797@2|Bacteria,1N0SN@1224|Proteobacteria,431H7@68525|delta/epsilon subdivisions,2WWTH@28221|Deltaproteobacteria,2Z202@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
REGS1_k127_1927275_5	38727.Pavir.J02682.1.p	1.877e-05	54.0	KOG0498@1|root,KOG0498@2759|Eukaryota,37I86@33090|Viridiplantae,3G92B@35493|Streptophyta,3KT2D@4447|Liliopsida,3IDKQ@38820|Poales	35493|Streptophyta	PT	Potassium channel SKOR	-	GO:0001101,GO:0003674,GO:0005215,GO:0005216,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006950,GO:0008150,GO:0008324,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009628,GO:0009719,GO:0009725,GO:0009737,GO:0009753,GO:0009987,GO:0010033,GO:0010035,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015271,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022832,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0033993,GO:0034220,GO:0042221,GO:0042391,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0055065,GO:0055067,GO:0055075,GO:0055080,GO:0055085,GO:0065007,GO:0065008,GO:0071804,GO:0071805,GO:0071944,GO:0097305,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1901700	-	ko:K21867	-	-	-	-	ko00000,ko02000	1.A.1.4	-	-	Ank_2,Ank_4,Ion_trans,KHA,cNMP_binding
REGS1_k127_1927275_4	886293.Sinac_7506	1.548e-06	62.0	COG1413@1|root,COG1413@2|Bacteria,2J011@203682|Planctomycetes	203682|Planctomycetes	C	E-Z type HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
REGS1_k127_1927275_3	1254432.SCE1572_21360	7.822e-09	68.0	COG0790@1|root,COG0790@2|Bacteria,1PFNI@1224|Proteobacteria,4346V@68525|delta/epsilon subdivisions,2X58N@28221|Deltaproteobacteria,2Z09P@29|Myxococcales	28221|Deltaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
REGS1_k127_1927275_6	1121946.AUAX01000017_gene5078	4.823e-05	55.0	COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria,4DJGB@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF5122) beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5122,HemolysinCabind
REGS1_k127_1951312_1	56780.SYN_01481	4.765e-146	491.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria,2MQZ2@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_1951312_0	404589.Anae109_2512	1.447e-170	578.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2YTTG@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
REGS1_k127_1951312_2	290397.Adeh_1254	4.82e-34	147.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2YVC1@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
REGS1_k127_1966827_0	404589.Anae109_1104	0.0	1465.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,2YU71@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
REGS1_k127_1966827_1	404589.Anae109_1103	6.947e-164	528.0	COG1752@1|root,COG1752@2|Bacteria,1R76S@1224|Proteobacteria	1224|Proteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
REGS1_k127_1966827_5	290397.Adeh_1051	6.089e-107	353.0	COG3177@1|root,COG3177@2|Bacteria,1Q2H9@1224|Proteobacteria,4383Y@68525|delta/epsilon subdivisions,2X3DX@28221|Deltaproteobacteria,2YVMK@29|Myxococcales	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
REGS1_k127_1966827_3	404589.Anae109_1100	2.008e-128	415.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2WJC7@28221|Deltaproteobacteria,2Z0QD@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
REGS1_k127_1966827_2	290397.Adeh_1049	1.67e-143	475.0	COG0618@1|root,COG0618@2|Bacteria,1N0JS@1224|Proteobacteria,42P1S@68525|delta/epsilon subdivisions,2WJV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
REGS1_k127_1966827_4	404589.Anae109_1097	3.842e-123	415.0	COG0515@1|root,COG0515@2|Bacteria	404589.Anae109_1097|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1966827_8	329726.AM1_0668	5.702e-08	64.0	COG0457@1|root,COG1994@1|root,COG0457@2|Bacteria,COG1994@2|Bacteria,1G1EH@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
REGS1_k127_1966827_6	290397.Adeh_1046	6.619e-53	193.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,42U47@68525|delta/epsilon subdivisions,2WQXE@28221|Deltaproteobacteria,2YVV5@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
REGS1_k127_1966827_7	404589.Anae109_1095	1.119e-27	113.0	COG1692@1|root,COG1692@2|Bacteria,1MW12@1224|Proteobacteria,42PCG@68525|delta/epsilon subdivisions,2WM8X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Metallophosphoesterase	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
REGS1_k127_1968414_8	1168065.DOK_04347	3.963e-10	63.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,1RNKF@1236|Gammaproteobacteria,1J53P@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	P	Ammonium Transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
REGS1_k127_1968414_4	404589.Anae109_3873	8.134e-137	444.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,42YTV@68525|delta/epsilon subdivisions,2WTY1@28221|Deltaproteobacteria,2YYJ0@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
REGS1_k127_1968414_5	290397.Adeh_3761	1.404e-69	239.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
REGS1_k127_1968414_3	290397.Adeh_3763	6.513e-151	482.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,2YUXX@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
REGS1_k127_1968414_7	290397.Adeh_3764	1.324e-23	115.0	COG3116@1|root,COG3116@2|Bacteria	2|Bacteria	D	cell division	ftsL	GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
REGS1_k127_1968414_0	404589.Anae109_3878	1.059e-237	751.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,2YTT3@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
REGS1_k127_1968414_1	290397.Adeh_3766	3.694e-226	729.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_1968414_2	290397.Adeh_3767	4.26e-170	578.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2YXRU@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_1968967_0	404589.Anae109_3444	1.584e-152	484.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria,2Z3J1@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
REGS1_k127_1968967_1	404589.Anae109_3445	1.15e-110	370.0	COG3637@1|root,COG3637@2|Bacteria,1Q8YQ@1224|Proteobacteria,42YH1@68525|delta/epsilon subdivisions,2WTT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1974707_5	644282.Deba_0532	2.966e-82	278.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,42R0Z@68525|delta/epsilon subdivisions,2WMNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NAD(P)H dehydrogenase (quinone)	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
REGS1_k127_1974707_7	1121920.AUAU01000007_gene543	4.032e-71	253.0	COG0604@1|root,COG0604@2|Bacteria,3Y4X4@57723|Acidobacteria	57723|Acidobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_1974707_4	1121413.JMKT01000014_gene2447	7.566e-125	404.0	COG2230@1|root,COG2230@2|Bacteria,1R1J6@1224|Proteobacteria,43DEG@68525|delta/epsilon subdivisions,2X8KD@28221|Deltaproteobacteria,2MHIT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_1974707_1	290397.Adeh_3919	1.402e-235	743.0	COG3203@1|root,COG3203@2|Bacteria,1MXEB@1224|Proteobacteria,42VNF@68525|delta/epsilon subdivisions,2WSCY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1302)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1302
REGS1_k127_1974707_2	290397.Adeh_3920	1.473e-217	682.0	28H52@1|root,2Z7HQ@2|Bacteria,1MXTF@1224|Proteobacteria,42NIU@68525|delta/epsilon subdivisions,2WJXK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1329)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1329
REGS1_k127_1974707_6	290397.Adeh_3921	1.667e-80	306.0	COG4447@1|root,COG4447@2|Bacteria,1R84R@1224|Proteobacteria,42RUQ@68525|delta/epsilon subdivisions,2WP02@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	protein related to plant photosystem II stability assembly factor	-	-	-	-	-	-	-	-	-	-	-	-	PSII_BNR
REGS1_k127_1974707_0	290397.Adeh_3922	6.031e-313	975.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42QGF@68525|delta/epsilon subdivisions,2WK2I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
REGS1_k127_1974707_3	290397.Adeh_3923	4.777e-179	578.0	COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,42U9J@68525|delta/epsilon subdivisions,2WQ39@28221|Deltaproteobacteria,2Z0NB@29|Myxococcales	28221|Deltaproteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	ko:K05548,ko:K05819,ko:K08195	-	-	-	-	ko00000,ko02000	2.A.1.15	-	-	MFS_1,MFS_4
REGS1_k127_1974707_8	292459.STH576	7.803e-39	157.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
REGS1_k127_1982462_0	215803.DB30_4593	1.16e-116	402.0	COG1305@1|root,COG3209@1|root,COG1305@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42R71@68525|delta/epsilon subdivisions,2WMW5@28221|Deltaproteobacteria,2Z1CW@29|Myxococcales	28221|Deltaproteobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,RHS,RHS_repeat,Transglut_core
REGS1_k127_2012828_0	404589.Anae109_0816	6.609e-97	329.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
REGS1_k127_2012828_1	290397.Adeh_3044	4.86e-61	217.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,2YU9C@29|Myxococcales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
REGS1_k127_2021388_12	298653.Franean1_6327	4.283e-08	54.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4ETQ1@85013|Frankiales	201174|Actinobacteria	C	PFAM aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_2021388_5	1349785.BAUG01000039_gene2104	5.089e-116	387.0	COG4122@1|root,COG4122@2|Bacteria,4NJV1@976|Bacteroidetes,1HYRV@117743|Flavobacteriia	976|Bacteroidetes	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
REGS1_k127_2021388_6	1123256.KB907925_gene1467	6.883e-90	317.0	28MCF@1|root,2ZAQK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2021388_8	1237149.C900_04365	3.139e-49	198.0	COG1629@1|root,COG4771@2|Bacteria,4NM9G@976|Bacteroidetes,47UNA@768503|Cytophagia	976|Bacteroidetes	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_dep_Rec
REGS1_k127_2021388_10	903818.KI912268_gene1510	2.295e-28	124.0	2E3CB@1|root,32YBM@2|Bacteria,3Y8J2@57723|Acidobacteria	57723|Acidobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
REGS1_k127_2021388_4	903818.KI912268_gene1511	3e-118	402.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,3Y3IC@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_2021388_9	269799.Gmet_2789	1.72e-43	180.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,42T3B@68525|delta/epsilon subdivisions,2WP8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
REGS1_k127_2021388_7	861299.J421_2962	2.5e-84	302.0	COG4191@1|root,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
REGS1_k127_2021388_1	404589.Anae109_0911	3.151e-174	566.0	COG0793@1|root,COG3485@1|root,COG0793@2|Bacteria,COG3485@2|Bacteria,1QT96@1224|Proteobacteria,437TZ@68525|delta/epsilon subdivisions,2X33H@28221|Deltaproteobacteria,2YU2B@29|Myxococcales	28221|Deltaproteobacteria	MQ	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,PDZ_2
REGS1_k127_2021388_0	404589.Anae109_1218	5.841e-269	837.0	COG3278@1|root,COG3278@2|Bacteria,1MU18@1224|Proteobacteria,42M5M@68525|delta/epsilon subdivisions,2WM27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the heme-copper respiratory oxidase family	-	-	1.9.3.1	ko:K00404,ko:K15862	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	COX1,FixO
REGS1_k127_2021388_2	290397.Adeh_1172	8.073e-133	432.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,42NZG@68525|delta/epsilon subdivisions,2WNX9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome C oxidase mono-heme subunit FixO	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
REGS1_k127_2021388_11	290397.Adeh_1173	1.099e-26	112.0	2ESEE@1|root,33JZ4@2|Bacteria	2|Bacteria	S	N-terminal domain of cytochrome oxidase-cbb3, FixP	-	-	-	-	-	-	-	-	-	-	-	-	FixP_N
REGS1_k127_2021388_3	404589.Anae109_1222	6.47e-123	400.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2WNZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
REGS1_k127_2022567_2	290397.Adeh_1303	1.002e-97	325.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,2YVXU@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
REGS1_k127_2022567_9	290397.Adeh_1302	6.133e-26	113.0	COG1426@1|root,COG1426@2|Bacteria	2|Bacteria	S	sequence-specific DNA binding	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25,PEGA
REGS1_k127_2022567_3	290397.Adeh_1301	1.276e-80	283.0	COG3063@1|root,COG3063@2|Bacteria,1RK88@1224|Proteobacteria,42SIP@68525|delta/epsilon subdivisions,2WPT7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	TPR repeat	tgl	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
REGS1_k127_2022567_4	290397.Adeh_1300	6.745e-59	209.0	2CIFB@1|root,33D8S@2|Bacteria,1P50Z@1224|Proteobacteria,432X4@68525|delta/epsilon subdivisions,2WXP1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2022567_1	404589.Anae109_2467	4.255e-103	342.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,2Z2Z2@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
REGS1_k127_2022567_7	290397.Adeh_1297	4.662e-46	175.0	COG0741@1|root,COG0741@2|Bacteria	2|Bacteria	M	lytic transglycosylase activity	slt	-	-	-	-	-	-	-	-	-	-	-	SLT
REGS1_k127_2022567_0	404589.Anae109_2471	2.174e-165	526.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2YUMI@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
REGS1_k127_2022567_8	404589.Anae109_2472	1.246e-30	135.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
REGS1_k127_2026718_19	545276.KB898731_gene2145	2.899e-15	82.0	COG1669@1|root,COG1669@2|Bacteria,1NMHI@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
REGS1_k127_2026718_20	748449.Halha_2371	6.692e-15	81.0	COG2445@1|root,COG2445@2|Bacteria,1VF8K@1239|Firmicutes,24QTN@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
REGS1_k127_2026718_14	247490.KSU1_D0857	1.448e-24	114.0	2F0IU@1|root,33TMI@2|Bacteria,2J1V2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2026718_10	247490.KSU1_D0856	4.835e-47	179.0	COG0755@1|root,COG0755@2|Bacteria,2J2E5@203682|Planctomycetes	203682|Planctomycetes	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_2026718_18	404589.Anae109_2528	1.102e-15	88.0	COG0810@1|root,COG0810@2|Bacteria,1NG3C@1224|Proteobacteria,42V3M@68525|delta/epsilon subdivisions,2WS05@28221|Deltaproteobacteria,2YZ7E@29|Myxococcales	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
REGS1_k127_2026718_1	290397.Adeh_1238	2.608e-172	576.0	COG0744@1|root,COG2982@1|root,COG0744@2|Bacteria,COG2982@2|Bacteria,1RDAQ@1224|Proteobacteria,42QW6@68525|delta/epsilon subdivisions,2WPZA@28221|Deltaproteobacteria,2YVC6@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	-	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
REGS1_k127_2026718_7	404589.Anae109_2530	4.55e-98	335.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
REGS1_k127_2026718_11	404589.Anae109_2531	1.857e-39	149.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria	1224|Proteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
REGS1_k127_2026718_12	290397.Adeh_1235	8.451e-35	134.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria,2Z1SJ@29|Myxococcales	28221|Deltaproteobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_2026718_9	290397.Adeh_1232	4.727e-48	176.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
REGS1_k127_2026718_4	290397.Adeh_1231	4.159e-135	445.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2YVDN@29|Myxococcales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
REGS1_k127_2026718_2	404589.Anae109_2540	3.076e-157	507.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2YV41@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_2026718_17	404589.Anae109_2550	2.115e-20	101.0	COG0515@1|root,COG0515@2|Bacteria	404589.Anae109_2550|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2026718_6	1121396.KB893077_gene743	4.156e-117	392.0	COG1228@1|root,COG3629@1|root,COG1228@2|Bacteria,COG3629@2|Bacteria,1Q0HP@1224|Proteobacteria,42URV@68525|delta/epsilon subdivisions,2WQQ1@28221|Deltaproteobacteria,2MPRD@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
REGS1_k127_2026718_0	404589.Anae109_2544	1.445e-281	880.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2YTVH@29|Myxococcales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
REGS1_k127_2026718_3	404589.Anae109_2545	3.106e-153	492.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2YU1B@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_2026718_8	1121438.JNJA01000012_gene1609	7.417e-53	199.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_2026718_5	290397.Adeh_1222	1.066e-122	397.0	COG1657@1|root,COG1657@2|Bacteria,1QX5U@1224|Proteobacteria,42ZX1@68525|delta/epsilon subdivisions,2WVF4@28221|Deltaproteobacteria,2YV56@29|Myxococcales	28221|Deltaproteobacteria	I	Domain of unknown function (DUF4159)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4159
REGS1_k127_2026718_13	404589.Anae109_2548	3.2e-28	115.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1MVWA@1224|Proteobacteria,42ZBA@68525|delta/epsilon subdivisions,2WUF4@28221|Deltaproteobacteria,2YUZP@29|Myxococcales	28221|Deltaproteobacteria	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
REGS1_k127_203766_3	357808.RoseRS_0421	1.46e-52	205.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
REGS1_k127_203766_0	404589.Anae109_4092	0.0	1590.0	COG0439@1|root,COG0511@1|root,COG0439@2|Bacteria,COG0511@2|Bacteria,1N71M@1224|Proteobacteria,42YTA@68525|delta/epsilon subdivisions,2WU1N@28221|Deltaproteobacteria,2YX0Y@29|Myxococcales	28221|Deltaproteobacteria	I	Pfam:CPSase_L_chain	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
REGS1_k127_203766_1	243231.GSU3299	0.0	1043.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,43TAX@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
REGS1_k127_203766_2	404589.Anae109_0271	7.268e-248	772.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2YU6I@29|Myxococcales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
REGS1_k127_2048152_0	671143.DAMO_0264	6.848e-92	323.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2NP0Q@2323|unclassified Bacteria	2|Bacteria	M	Bacterial sugar transferase	wcaJ	-	-	ko:K03606,ko:K20997	ko02025,ko05111,map02025,map05111	-	-	-	ko00000,ko00001	-	-	-	Bac_transf,CoA_binding_3
REGS1_k127_2048152_1	671143.DAMO_0263	5.736e-70	243.0	COG0438@1|root,COG0438@2|Bacteria,2NP1P@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase Family 4	wcnD	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_2056018_2	404589.Anae109_1201	1.64e-94	317.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
REGS1_k127_2056018_0	269799.Gmet_0256	2.19e-233	733.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42NT5@68525|delta/epsilon subdivisions,2WIWR@28221|Deltaproteobacteria,43W00@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	alkK	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
REGS1_k127_2056018_1	290397.Adeh_1156	2.542e-182	588.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,2YV2H@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
REGS1_k127_2056018_3	290397.Adeh_4128	1.646e-75	263.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
REGS1_k127_2061731_5	404589.Anae109_2482	6.329e-14	73.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
REGS1_k127_2061731_0	290397.Adeh_1284	0.0	1026.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_2061731_1	290397.Adeh_1285	6.316e-233	763.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
REGS1_k127_2061731_3	483219.LILAB_09850	1.425e-110	365.0	COG0491@1|root,COG0491@2|Bacteria,1MUSY@1224|Proteobacteria,438ZA@68525|delta/epsilon subdivisions,2XA0R@28221|Deltaproteobacteria,2Z00H@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_2061731_2	290397.Adeh_1287	6.533e-124	402.0	COG0483@1|root,COG0483@2|Bacteria,1PPJ0@1224|Proteobacteria,4307A@68525|delta/epsilon subdivisions,2WV7X@28221|Deltaproteobacteria,2YVIM@29|Myxococcales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Inositol_P
REGS1_k127_2061731_4	404589.Anae109_2477	7.293e-31	122.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MB6@68525|delta/epsilon subdivisions,2WJMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	ato-2	-	2.8.3.18,3.1.2.1	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00227,R10343	RC00004,RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1125	AcetylCoA_hyd_C,AcetylCoA_hydro
REGS1_k127_2063117_0	483219.LILAB_07880	6.376e-64	236.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
REGS1_k127_2063117_1	404589.Anae109_3468	1.788e-47	176.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2YUGZ@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
REGS1_k127_2119954_0	404589.Anae109_4110	0.0	1073.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2X64M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdopterin,Molydop_binding
REGS1_k127_2119954_2	404589.Anae109_2592	8.282e-33	129.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	kmtR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0010045,GO:0032025,GO:0042221,GO:0050896,GO:0097159,GO:1901363	-	ko:K03892,ko:K22298	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
REGS1_k127_2119954_1	290397.Adeh_2634	7.168e-117	389.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CCF@68525|delta/epsilon subdivisions,2X60X@28221|Deltaproteobacteria,2Z384@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_2143533_7	290397.Adeh_2368	2.014e-98	323.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2YZ16@29|Myxococcales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_2143533_10	404589.Anae109_1508	1.932e-51	184.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
REGS1_k127_2143533_4	290397.Adeh_2360	4.112e-181	576.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,2YV7V@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
REGS1_k127_2143533_1	290397.Adeh_2359	2.323e-233	736.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
REGS1_k127_2143533_5	404589.Anae109_1511	1.773e-141	463.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria,2Z11I@29|Myxococcales	28221|Deltaproteobacteria	M	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
REGS1_k127_2143533_6	404589.Anae109_4074	1.61e-112	374.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
REGS1_k127_2143533_3	290397.Adeh_2355	2.752e-217	686.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2YUPE@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_2143533_13	290397.Adeh_2354	7.32e-21	101.0	COG5652@1|root,COG5652@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
REGS1_k127_2143533_9	404589.Anae109_1520	1.398e-71	251.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WP23@28221|Deltaproteobacteria,2Z0GF@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
REGS1_k127_2143533_11	290397.Adeh_2352	6.013e-51	193.0	COG0664@1|root,COG0664@2|Bacteria,1RDKD@1224|Proteobacteria	1224|Proteobacteria	T	PFAM Cyclic nucleotide-binding	MA20_24885	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_2143533_8	290397.Adeh_2351	5.671e-90	310.0	COG0586@1|root,COG0586@2|Bacteria,1R6V4@1224|Proteobacteria,42XP4@68525|delta/epsilon subdivisions,2WT5P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_2143533_2	483219.LILAB_27060	1.458e-230	737.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YY4Y@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70,PilZ
REGS1_k127_2143533_0	290397.Adeh_2349	2.242e-262	816.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2YUG2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
REGS1_k127_2143533_12	290397.Adeh_2348	1.437e-24	105.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,42M0I@68525|delta/epsilon subdivisions,2WJ6D@28221|Deltaproteobacteria,2YTZV@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
REGS1_k127_2151672_1	404589.Anae109_3466	4.229e-58	215.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
REGS1_k127_2151672_2	378806.STAUR_8052	3.694e-34	140.0	2EV1C@1|root,33NGG@2|Bacteria,1NKKY@1224|Proteobacteria,42X6Y@68525|delta/epsilon subdivisions,2WTH7@28221|Deltaproteobacteria,2Z0VE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2151672_0	1242864.D187_007813	2.218e-192	632.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_2155454_0	404589.Anae109_1299	4.671e-155	502.0	COG2211@1|root,COG2211@2|Bacteria,1QTSE@1224|Proteobacteria,43C8U@68525|delta/epsilon subdivisions,2X7J6@28221|Deltaproteobacteria,2Z3H1@29|Myxococcales	28221|Deltaproteobacteria	G	Acetyl-coenzyme A transporter 1	-	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
REGS1_k127_2155454_1	391625.PPSIR1_26598	8.622e-57	207.0	COG2859@1|root,COG2859@2|Bacteria,1NBCQ@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF541)	-	-	-	-	-	-	-	-	-	-	-	-	SIMPL
REGS1_k127_2155454_2	84531.JMTZ01000166_gene1270	4.794e-43	169.0	COG2968@1|root,COG2968@2|Bacteria	2|Bacteria	S	cellular response to heat	-	-	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
REGS1_k127_2155454_4	290397.Adeh_2563	1.983e-05	49.0	2F8HZ@1|root,340WS@2|Bacteria,1NJHM@1224|Proteobacteria,430Z9@68525|delta/epsilon subdivisions,2WVPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2160811_10	483219.LILAB_23300	4.249e-05	47.0	COG1300@1|root,COG1300@2|Bacteria,1Q1GN@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
REGS1_k127_2160811_3	1163617.SCD_n01130	4.125e-100	337.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,2VSSE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	auxin efflux carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
REGS1_k127_2160811_8	755732.Fluta_1281	3.506e-22	101.0	2DNSK@1|root,32YXM@2|Bacteria,4P2C6@976|Bacteroidetes,1I8TN@117743|Flavobacteriia	976|Bacteroidetes	S	Domain of unknown function (DUF4259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4259
REGS1_k127_2160811_4	443143.GM18_3296	1.165e-54	202.0	arCOG03165@1|root,30AIC@2|Bacteria,1QYWT@1224|Proteobacteria,43CDP@68525|delta/epsilon subdivisions,2X7PJ@28221|Deltaproteobacteria,43V63@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2160811_1	404589.Anae109_2985	7.967e-139	448.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2YWUY@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
REGS1_k127_2160811_2	404589.Anae109_2639	2.03e-111	381.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
REGS1_k127_2160811_0	290397.Adeh_2653	7.449e-185	606.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,2YTWF@29|Myxococcales	28221|Deltaproteobacteria	D	Stage II sporulation protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIID
REGS1_k127_2160811_9	290397.Adeh_2179	2.137e-06	51.0	COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria,43E8F@68525|delta/epsilon subdivisions,2WZZP@28221|Deltaproteobacteria,2Z1JY@29|Myxococcales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_2169803_0	290397.Adeh_0668	6.989e-128	429.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2Z2I5@29|Myxococcales	28221|Deltaproteobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
REGS1_k127_2169803_3	290397.Adeh_0667	1.081e-106	353.0	COG2177@1|root,COG2177@2|Bacteria,1R85B@1224|Proteobacteria,42PXG@68525|delta/epsilon subdivisions,2WKX3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
REGS1_k127_2169803_2	290397.Adeh_0666	3.452e-109	361.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2YV0E@29|Myxococcales	28221|Deltaproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
REGS1_k127_2169803_5	290397.Adeh_3854	2.357e-05	53.0	2CHH4@1|root,32SC0@2|Bacteria,1NPE4@1224|Proteobacteria	1224|Proteobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
REGS1_k127_2169803_4	290397.Adeh_0665	2.143e-81	281.0	2E2XW@1|root,32XYS@2|Bacteria,1N3ID@1224|Proteobacteria,42UFM@68525|delta/epsilon subdivisions,2WQKF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2169803_1	290397.Adeh_0664	1.995e-122	398.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2YY1K@29|Myxococcales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
REGS1_k127_218334_2	404589.Anae109_1139	1.045e-185	584.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2YUJG@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
REGS1_k127_218334_7	404589.Anae109_1140	3.036e-14	85.0	COG2740@1|root,COG2740@2|Bacteria	2|Bacteria	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
REGS1_k127_218334_0	290397.Adeh_1102	0.0	1212.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,2YU1F@29|Myxococcales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
REGS1_k127_218334_4	404589.Anae109_1142	5.936e-52	186.0	COG1550@1|root,COG1550@2|Bacteria,1NBXZ@1224|Proteobacteria,42W9E@68525|delta/epsilon subdivisions,2WRK0@28221|Deltaproteobacteria,2YW04@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
REGS1_k127_218334_5	290397.Adeh_1104	7.546e-52	187.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42U0Y@68525|delta/epsilon subdivisions,2WR00@28221|Deltaproteobacteria,2Z08B@29|Myxococcales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
REGS1_k127_218334_3	290397.Adeh_1105	4.406e-104	347.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C,TruB_C_2,TruB_N
REGS1_k127_218334_6	290397.Adeh_1106	4.627e-36	142.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
REGS1_k127_218334_1	290397.Adeh_1107	8.205e-270	838.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2YUER@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
REGS1_k127_2211294_5	290397.Adeh_3877	7.274e-08	57.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1QYGN@1224|Proteobacteria,43CCX@68525|delta/epsilon subdivisions,2WXED@28221|Deltaproteobacteria,2YZUY@29|Myxococcales	28221|Deltaproteobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
REGS1_k127_2211294_1	404589.Anae109_4052	3.474e-94	321.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42ZH7@68525|delta/epsilon subdivisions,2WV12@28221|Deltaproteobacteria,2Z0K0@29|Myxococcales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
REGS1_k127_2211294_4	266779.Meso_2192	3.74e-25	110.0	COG3832@1|root,COG3832@2|Bacteria,1RJ1C@1224|Proteobacteria,2VF8Y@28211|Alphaproteobacteria,43RFT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
REGS1_k127_2211294_3	1298863.AUEP01000005_gene2579	7.738e-51	193.0	COG0702@1|root,COG0702@2|Bacteria,2IS0B@201174|Actinobacteria	201174|Actinobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2211294_2	290397.Adeh_0651	1.233e-51	203.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
REGS1_k127_2211294_0	1519464.HY22_01480	2.756e-136	448.0	COG0841@1|root,COG0841@2|Bacteria	2|Bacteria	V	transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_2243255_4	523841.HFX_2676	4.067e-33	136.0	COG0574@1|root,arCOG01114@2157|Archaea,2XVSY@28890|Euryarchaeota,23UK4@183963|Halobacteria	183963|Halobacteria	G	COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
REGS1_k127_2243255_2	404589.Anae109_4171	4.782e-118	384.0	COG3694@1|root,COG3694@2|Bacteria,1NAPK@1224|Proteobacteria,42X7R@68525|delta/epsilon subdivisions,2WSZA@28221|Deltaproteobacteria,2YVA3@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
REGS1_k127_2243255_3	290397.Adeh_0399	1.482e-106	365.0	COG4587@1|root,COG4587@2|Bacteria,1NBY6@1224|Proteobacteria,42XYD@68525|delta/epsilon subdivisions,2WY0V@28221|Deltaproteobacteria,2YVAD@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
REGS1_k127_2243255_0	290397.Adeh_0396	3.842e-174	550.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,42NQB@68525|delta/epsilon subdivisions,2WIWW@28221|Deltaproteobacteria,2YTWZ@29|Myxococcales	28221|Deltaproteobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
REGS1_k127_2243255_1	404589.Anae109_4187	5.097e-123	401.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2YUBF@29|Myxococcales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_2271133_0	215803.DB30_6050	8.56e-61	216.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,2YVBP@29|Myxococcales	28221|Deltaproteobacteria	M	polysaccharide export	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
REGS1_k127_2271133_3	1121033.AUCF01000017_gene3889	1.323e-23	119.0	COG1404@1|root,COG2931@1|root,COG4733@1|root,COG1404@2|Bacteria,COG2931@2|Bacteria,COG4733@2|Bacteria,1Q0R4@1224|Proteobacteria,2V8X6@28211|Alphaproteobacteria,2JWZH@204441|Rhodospirillales	204441|Rhodospirillales	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_227716_1	215803.DB30_0441	2.508e-111	374.0	COG1063@1|root,COG1063@2|Bacteria,1NXSN@1224|Proteobacteria,438FZ@68525|delta/epsilon subdivisions,2X3QX@28221|Deltaproteobacteria,2YWVR@29|Myxococcales	28221|Deltaproteobacteria	E	Glucose dehydrogenase C-terminus	gcd	-	-	-	-	-	-	-	-	-	-	-	ADH_N,Glu_dehyd_C
REGS1_k127_227716_0	861299.J421_1867	7.254e-221	707.0	COG1429@1|root,COG1429@2|Bacteria	2|Bacteria	H	ligase activity, forming nitrogen-metal bonds	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel,Glyco_hydro_63
REGS1_k127_2306394_2	404589.Anae109_2498	1.221e-32	127.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2YVAI@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, CarD family	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
REGS1_k127_2306394_0	290397.Adeh_1270	7.632e-242	771.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2YUX0@29|Myxococcales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
REGS1_k127_2306394_3	290397.Adeh_1268	1.993e-16	94.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	essC	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,Yop-YscD_cpl
REGS1_k127_2306394_1	404589.Anae109_2503	5.13e-43	179.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_2503|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2306394_4	1382359.JIAL01000001_gene1846	1.335e-09	71.0	COG0457@1|root,COG0457@2|Bacteria,3Y5A8@57723|Acidobacteria,2JNC1@204432|Acidobacteriia	204432|Acidobacteriia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
REGS1_k127_2314675_0	316056.RPC_4894	1.409e-167	533.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,3JVP4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
REGS1_k127_2314675_2	1297742.A176_00023	5.183e-100	332.0	COG1985@1|root,COG1985@2|Bacteria,1PXWC@1224|Proteobacteria	1224|Proteobacteria	H	reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_2314675_1	290397.Adeh_3171	5.122e-155	493.0	COG0583@1|root,COG0583@2|Bacteria,1MU2E@1224|Proteobacteria,42T5W@68525|delta/epsilon subdivisions,2WPVR@28221|Deltaproteobacteria,2YU5I@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
REGS1_k127_2314675_4	1242864.D187_010452	2.201e-14	86.0	COG2273@1|root,COG2273@2|Bacteria,1Q24F@1224|Proteobacteria,43F1J@68525|delta/epsilon subdivisions,2X30E@28221|Deltaproteobacteria,2YTW9@29|Myxococcales	28221|Deltaproteobacteria	G	Carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Glyco_hydro_16
REGS1_k127_2314675_3	1463887.KL590085_gene537	6.988e-30	136.0	COG1361@1|root,COG2706@1|root,COG1361@2|Bacteria,COG2706@2|Bacteria	2|Bacteria	G	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,VCBS
REGS1_k127_2315987_16	404589.Anae109_0536	1.067e-23	111.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
REGS1_k127_2315987_20	290397.Adeh_3602	2.739e-05	56.0	COG5430@1|root,COG5430@2|Bacteria,1MZNQ@1224|Proteobacteria	1224|Proteobacteria	S	Spore Coat Protein	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
REGS1_k127_2315987_17	452662.SJA_C1-07070	9.321e-20	95.0	COG5430@1|root,COG5430@2|Bacteria,1N5AX@1224|Proteobacteria,2UD10@28211|Alphaproteobacteria,2K70Q@204457|Sphingomonadales	204457|Sphingomonadales	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
REGS1_k127_2315987_10	404589.Anae109_0414	1.501e-82	302.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	uptE	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
REGS1_k127_2315987_14	290397.Adeh_1657	3.811e-34	150.0	COG1051@1|root,COG1051@2|Bacteria,1QUNH@1224|Proteobacteria,43C4F@68525|delta/epsilon subdivisions,2WS06@28221|Deltaproteobacteria,2Z2IP@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
REGS1_k127_2315987_5	404589.Anae109_2153	2.397e-121	399.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,42V3F@68525|delta/epsilon subdivisions,2WR8K@28221|Deltaproteobacteria,2YVGH@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ enzyme repeat	yfgL	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
REGS1_k127_2315987_12	290397.Adeh_1655	1.166e-58	212.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	CP_0079	-	-	ko:K15368	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_21,TPR_6
REGS1_k127_2315987_0	404589.Anae109_2155	9.922e-234	739.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,2YU6J@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
REGS1_k127_2315987_3	404589.Anae109_2156	2.922e-152	486.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,2YYQ7@29|Myxococcales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
REGS1_k127_2315987_7	290397.Adeh_1652	7.603e-96	315.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42NWS@68525|delta/epsilon subdivisions,2X60R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
REGS1_k127_2315987_8	404589.Anae109_2158	5.552e-93	316.0	COG0652@1|root,COG0652@2|Bacteria	2|Bacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiA	GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030312,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0140096,GO:1901564	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
REGS1_k127_2315987_9	290397.Adeh_1650	1.916e-90	310.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,2YVFW@29|Myxococcales	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
REGS1_k127_2315987_6	290397.Adeh_1833	8.282e-99	329.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	ko:K13613,ko:K15677	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25,Methyltransf_31,NUDIX,PCMT,PP-binding,PS-DH,ketoacyl-synt
REGS1_k127_2315987_4	404589.Anae109_1984	2.141e-149	481.0	COG0392@1|root,COG0392@2|Bacteria,1PPSZ@1224|Proteobacteria,434R6@68525|delta/epsilon subdivisions,2WZ2B@28221|Deltaproteobacteria,2Z16A@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
REGS1_k127_2315987_11	1278073.MYSTI_04911	1.966e-67	237.0	COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,42UBJ@68525|delta/epsilon subdivisions,2WQ5M@28221|Deltaproteobacteria,2YVNX@29|Myxococcales	28221|Deltaproteobacteria	GM	PFAM PHP domain protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
REGS1_k127_2315987_18	404589.Anae109_1982	2.975e-13	80.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,42XRW@68525|delta/epsilon subdivisions,2X2JD@28221|Deltaproteobacteria,2YW45@29|Myxococcales	28221|Deltaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
REGS1_k127_2315987_13	404589.Anae109_1981	3.997e-45	168.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
REGS1_k127_2315987_1	404589.Anae109_1980	1.182e-228	736.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
REGS1_k127_2324769_9	1121403.AUCV01000001_gene869	3.205e-43	160.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42MKP@68525|delta/epsilon subdivisions,2WJU9@28221|Deltaproteobacteria,2MJJN@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_2324769_3	1167006.UWK_00090	1.669e-119	399.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42TE0@68525|delta/epsilon subdivisions,2WPEP@28221|Deltaproteobacteria,2MKDG@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_2324769_6	1167006.UWK_00089	7.224e-88	313.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJIS@28221|Deltaproteobacteria,2MIA1@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_2324769_5	1121403.AUCV01000001_gene872	5.48e-95	317.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M5A@68525|delta/epsilon subdivisions,2WK03@28221|Deltaproteobacteria,2MJNZ@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ABC transporter	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_2324769_0	589865.DaAHT2_0100	2.965e-184	597.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42MSQ@68525|delta/epsilon subdivisions,2WISJ@28221|Deltaproteobacteria,2MPW4@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-1	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
REGS1_k127_2324769_11	1408427.JADB01000004_gene769	1.455e-06	56.0	COG2261@1|root,COG2261@2|Bacteria,1N88H@1224|Proteobacteria,2UFV9@28211|Alphaproteobacteria,48UB9@772|Bartonellaceae	28211|Alphaproteobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
REGS1_k127_2324769_1	290397.Adeh_4107	3.59e-150	513.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
REGS1_k127_2324769_4	290397.Adeh_3704	1.41e-112	383.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,439XE@68525|delta/epsilon subdivisions,2X4RA@28221|Deltaproteobacteria,2YZFJ@29|Myxococcales	28221|Deltaproteobacteria	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
REGS1_k127_2324769_2	903818.KI912268_gene3221	4.424e-139	453.0	COG2270@1|root,COG2270@2|Bacteria,3Y9EJ@57723|Acidobacteria	57723|Acidobacteria	S	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
REGS1_k127_2324769_10	1267535.KB906767_gene4200	1.021e-27	116.0	COG0745@1|root,COG0745@2|Bacteria,3Y81M@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_2324769_8	1041139.KB902746_gene3230	4.434e-48	190.0	COG2199@1|root,COG4192@1|root,COG5002@1|root,COG3706@2|Bacteria,COG4192@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,2TZD4@28211|Alphaproteobacteria,4BP1D@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_7,Response_reg
REGS1_k127_2324769_7	290397.Adeh_0433	2.602e-61	223.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria,2YWNV@29|Myxococcales	28221|Deltaproteobacteria	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
REGS1_k127_2326312_0	41431.PCC8801_4397	4.971e-266	835.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1G0Q0@1117|Cyanobacteria,3KGRS@43988|Cyanothece	1117|Cyanobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
REGS1_k127_2326312_2	1121920.AUAU01000018_gene1800	4.167e-216	680.0	COG0436@1|root,COG0436@2|Bacteria,3Y5C9@57723|Acidobacteria	57723|Acidobacteria	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_2326312_5	404589.Anae109_0466	2.195e-72	253.0	COG1352@1|root,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-transferase	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
REGS1_k127_2326312_3	404589.Anae109_0469	1.591e-206	669.0	COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_2326312_7	404589.Anae109_0468	1.625e-36	145.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_2326312_6	404589.Anae109_0467	1.465e-55	196.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	pilG	-	-	ko:K02657,ko:K03413	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_2326312_4	404589.Anae109_0463	4.106e-204	657.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,2YTY5@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
REGS1_k127_2326312_1	290397.Adeh_3959	9.125e-253	785.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2YU49@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
REGS1_k127_2335860_5	290397.Adeh_0615	2.914e-30	120.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1MVP3@1224|Proteobacteria,43AKK@68525|delta/epsilon subdivisions,2X60J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16,TPR_19
REGS1_k127_2335860_2	404589.Anae109_0660	4.1e-63	222.0	COG0745@1|root,COG0745@2|Bacteria,1QX5E@1224|Proteobacteria,432PC@68525|delta/epsilon subdivisions,2WY3G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_2335860_0	290397.Adeh_0617	2.061e-196	620.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
REGS1_k127_2335860_1	290397.Adeh_0618	1.461e-117	384.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P3C@68525|delta/epsilon subdivisions,2X21N@28221|Deltaproteobacteria,2Z2ZB@29|Myxococcales	28221|Deltaproteobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_2335860_3	290397.Adeh_0620	3.348e-49	195.0	COG0295@1|root,COG0295@2|Bacteria,1MY2R@1224|Proteobacteria,42UZH@68525|delta/epsilon subdivisions,2WR2R@28221|Deltaproteobacteria,2YVFS@29|Myxococcales	28221|Deltaproteobacteria	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
REGS1_k127_2335860_6	1278073.MYSTI_05613	1.274e-27	123.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria,2Z3FM@29|Myxococcales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_2346714_3	290397.Adeh_0046	3.586e-144	470.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria,42P08@68525|delta/epsilon subdivisions,2WJXV@28221|Deltaproteobacteria,2YYSQ@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
REGS1_k127_2346714_0	404589.Anae109_0043	4.964e-271	846.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2Z24J@29|Myxococcales	28221|Deltaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	iorA-1	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
REGS1_k127_2346714_5	290397.Adeh_0039	1.087e-63	243.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,42SK4@68525|delta/epsilon subdivisions,2WPI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM pyruvate ferredoxin flavodoxin oxidoreductase	iorB-1	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
REGS1_k127_2346714_2	404589.Anae109_0041	5.93e-231	721.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42NKD@68525|delta/epsilon subdivisions,2WIWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
REGS1_k127_2346714_4	404589.Anae109_0040	7.863e-64	221.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WQBM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
REGS1_k127_2346714_1	404589.Anae109_0039	2.539e-237	738.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42MSQ@68525|delta/epsilon subdivisions,2WISJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-1	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
REGS1_k127_2346714_7	1379270.AUXF01000002_gene1781	1.818e-35	140.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like_2
REGS1_k127_2346714_6	1122921.KB898204_gene3504	6.728e-46	179.0	COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli,26XT9@186822|Paenibacillaceae	91061|Bacilli	P	Alkylphosphonate utilization protein	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
REGS1_k127_2350758_0	1120925.F941_02615	4.722e-100	339.0	COG3746@1|root,COG3746@2|Bacteria,1R5WJ@1224|Proteobacteria,1SM6F@1236|Gammaproteobacteria,3NK33@468|Moraxellaceae	1236|Gammaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2350758_1	448385.sce1321	2.116e-89	311.0	COG0715@1|root,COG0715@2|Bacteria,1N2ZA@1224|Proteobacteria	1224|Proteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K15553	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	NMT1
REGS1_k127_2356555_2	1242864.D187_008344	5.654e-35	138.0	COG0007@1|root,COG0007@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2YUYH@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
REGS1_k127_2356555_1	1254432.SCE1572_01950	2.752e-50	191.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,43EV8@68525|delta/epsilon subdivisions,2X1Y7@28221|Deltaproteobacteria,2Z07M@29|Myxococcales	28221|Deltaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	-	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
REGS1_k127_2356555_0	448385.sce0213	4.193e-163	541.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,2YZN0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
REGS1_k127_2356555_3	1254432.SCE1572_01935	3.92e-12	75.0	COG1270@1|root,COG1270@2|Bacteria,1MURM@1224|Proteobacteria,42PDX@68525|delta/epsilon subdivisions,2WKH4@28221|Deltaproteobacteria,2Z05J@29|Myxococcales	28221|Deltaproteobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
REGS1_k127_2379852_10	404589.Anae109_1146	5.851e-71	242.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2YUER@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
REGS1_k127_2379852_9	404589.Anae109_1147	3.102e-74	254.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria,2YV9H@29|Myxococcales	28221|Deltaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
REGS1_k127_2379852_3	1502724.FF80_01471	1.196e-146	477.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2TQUE@28211|Alphaproteobacteria,3N6DZ@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
REGS1_k127_2379852_12	1242864.D187_009178	2.767e-47	177.0	COG4566@1|root,COG4566@2|Bacteria,1R47Z@1224|Proteobacteria,43065@68525|delta/epsilon subdivisions,2WV8S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_2379852_1	290397.Adeh_1112	2.824e-173	556.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2YUIU@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
REGS1_k127_2379852_6	290397.Adeh_1113	3.809e-92	310.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42R3K@68525|delta/epsilon subdivisions,2WM8S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K02533,ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_2379852_0	404589.Anae109_0490	9.122e-178	570.0	COG1858@1|root,COG1858@2|Bacteria,1N4E1@1224|Proteobacteria,42Z8C@68525|delta/epsilon subdivisions,2WU08@28221|Deltaproteobacteria,2YXJP@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2379852_11	398767.Glov_0104	1.233e-70	242.0	COG2406@1|root,COG2406@2|Bacteria,1RE25@1224|Proteobacteria,42PJ1@68525|delta/epsilon subdivisions,2WNTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Ferritin Dps family protein	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
REGS1_k127_2379852_8	404589.Anae109_1156	2.276e-76	283.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,42USC@68525|delta/epsilon subdivisions,2WQMY@28221|Deltaproteobacteria,2Z2ZG@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_2379852_2	404589.Anae109_1157	3.443e-152	499.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
REGS1_k127_2379852_4	290397.Adeh_1118	1.139e-118	395.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2X75V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD,HD_5,sCache_3_2
REGS1_k127_2379852_14	290397.Adeh_1119	1.881e-39	154.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HisKA,Hpt,PAS_3,PAS_4,Response_reg
REGS1_k127_2379852_5	404589.Anae109_1160	1.129e-99	329.0	COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,1RGUX@1224|Proteobacteria,437BZ@68525|delta/epsilon subdivisions,2WQNB@28221|Deltaproteobacteria,2YVJC@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	2.8.1.12	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
REGS1_k127_2379852_7	290397.Adeh_1121	2.193e-91	311.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YV9N@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
REGS1_k127_2385912_7	582515.KR51_00001230	1.711e-32	128.0	COG1012@1|root,COG1012@2|Bacteria,1G2U1@1117|Cyanobacteria	1117|Cyanobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.5	ko:K00128,ko:K00129	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00350,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00980,ko00981,ko00982,ko01100,ko01110,ko01120,ko01130,ko05204,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00350,map00360,map00380,map00410,map00561,map00620,map00625,map00903,map00980,map00981,map00982,map01100,map01110,map01120,map01130,map05204	M00135	R00264,R00631,R00710,R00711,R00904,R01752,R01986,R02536,R02537,R02549,R02678,R02695,R02697,R02940,R02957,R03283,R03300,R03302,R03869,R04065,R04506,R04882,R04883,R04888,R04889,R04891,R04892,R04903,R04996,R05050,R05237,R05238,R05286,R06366,R07104,R08146,R08282,R08283,R08307	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500,RC01735	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_2385912_6	378806.STAUR_3165	1.478e-68	261.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,42SGU@68525|delta/epsilon subdivisions,2WPBP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
REGS1_k127_2385912_0	290397.Adeh_2970	4.336e-165	539.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWC8@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_2385912_4	1242864.D187_001641	1.118e-88	317.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2WMVB@28221|Deltaproteobacteria,2YUCK@29|Myxococcales	28221|Deltaproteobacteria	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_2385912_1	290397.Adeh_2972	3.998e-135	445.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2YWS4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
REGS1_k127_2385912_2	290397.Adeh_4213	8.351e-122	409.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HWE_HK,HisKA,PAS_3,Response_reg
REGS1_k127_2385912_3	439235.Dalk_4326	3.664e-96	329.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42QMQ@68525|delta/epsilon subdivisions,2WN4S@28221|Deltaproteobacteria,2MJWK@213118|Desulfobacterales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,GGDEF
REGS1_k127_2385912_5	290397.Adeh_3960	1.782e-79	269.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,42TMM@68525|delta/epsilon subdivisions,2WQ6S@28221|Deltaproteobacteria,2YVZ3@29|Myxococcales	28221|Deltaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
REGS1_k127_2385912_8	404589.Anae109_0462	4.192e-15	74.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2YU49@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
REGS1_k127_2397606_4	404589.Anae109_0748	1.957e-78	273.0	COG4669@1|root,COG4669@2|Bacteria,1N69F@1224|Proteobacteria,42T6F@68525|delta/epsilon subdivisions,2WPNY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Secretory protein of YscJ/FliF family	nolT	-	-	ko:K03222	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	YscJ_FliF
REGS1_k127_2397606_2	404589.Anae109_0747	4.796e-82	285.0	COG1868@1|root,COG1886@1|root,COG1868@2|Bacteria,COG1886@2|Bacteria	2|Bacteria	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliM	GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0008150,GO:0009288,GO:0009425,GO:0009605,GO:0016020,GO:0040011,GO:0042221,GO:0042330,GO:0042995,GO:0043226,GO:0043228,GO:0044403,GO:0044419,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243,GO:0071944	-	ko:K02416,ko:K02417,ko:K03225	ko02030,ko02040,ko03070,map02030,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliM,FliMN_C
REGS1_k127_2397606_3	290397.Adeh_0703	5.427e-80	272.0	COG4790@1|root,COG4790@2|Bacteria,1R34E@1224|Proteobacteria	1224|Proteobacteria	U	type iii secretion	hrcR	-	-	ko:K03226	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	FliP
REGS1_k127_2397606_6	290397.Adeh_0702	2.057e-23	112.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,42VAB@68525|delta/epsilon subdivisions,2WR6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420,ko:K03227	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_3
REGS1_k127_2397606_5	404589.Anae109_0743	3.906e-68	245.0	COG1684@1|root,COG1684@2|Bacteria	2|Bacteria	N	bacterial-type flagellum assembly	fliR	-	-	ko:K02421,ko:K03228,ko:K13820	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_1
REGS1_k127_2397606_1	290397.Adeh_0700	4.068e-100	342.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2WJIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	yscU	-	-	ko:K02401,ko:K03229	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_2
REGS1_k127_2397606_0	404589.Anae109_0741	7.504e-237	752.0	COG4789@1|root,COG4789@2|Bacteria,1R346@1224|Proteobacteria,43DIZ@68525|delta/epsilon subdivisions,2X8Q9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type III secretion protein	-	-	-	ko:K03230	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	FHIPEP
REGS1_k127_2411010_3	335283.Neut_2196	3.564e-16	89.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VU4X@28216|Betaproteobacteria,372W6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
REGS1_k127_2411010_1	1123399.AQVE01000006_gene3563	4.709e-38	150.0	2DNKW@1|root,32Y18@2|Bacteria,1ND1M@1224|Proteobacteria,1SQBD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2411010_0	290397.Adeh_3457	5.062e-240	756.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,2YU0Z@29|Myxococcales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
REGS1_k127_2411010_2	404589.Anae109_3567	3.002e-23	100.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria,2Z262@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
REGS1_k127_2417169_0	290397.Adeh_3184	0.0	4153.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2YV3K@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_2417169_2	266117.Rxyl_2842	1.807e-50	187.0	COG0590@1|root,COG0590@2|Bacteria,2I9KR@201174|Actinobacteria	201174|Actinobacteria	FJ	CMP dCMP deaminase, zinc-binding	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
REGS1_k127_2417169_1	1242864.D187_006668	1.145e-67	246.0	COG2885@1|root,COG2885@2|Bacteria,1R4WG@1224|Proteobacteria,42TD5@68525|delta/epsilon subdivisions,2WP3U@28221|Deltaproteobacteria,2YZG5@29|Myxococcales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	DUF5011,HYR,OMP_b-brl,OmpA,TSP_3
REGS1_k127_2432434_2	1122169.AREN01000041_gene44	1.015e-15	78.0	COG3752@1|root,COG3752@2|Bacteria,1RD8F@1224|Proteobacteria,1S3R5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1295)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295
REGS1_k127_2432434_1	671143.DAMO_0826	1.763e-58	213.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	ko:K02569,ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT,Cytochrome_C7
REGS1_k127_2432434_0	502025.Hoch_3806	3.759e-117	396.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,42NS6@68525|delta/epsilon subdivisions,2WKYJ@28221|Deltaproteobacteria,2YU4P@29|Myxococcales	28221|Deltaproteobacteria	H	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
REGS1_k127_2438437_11	404589.Anae109_2878	2.623e-29	135.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M8C@68525|delta/epsilon subdivisions,2WJB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02688	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PrpR_N,Sigma54_activat
REGS1_k127_2438437_2	290397.Adeh_1627	2.157e-149	492.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,2YU09@29|Myxococcales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
REGS1_k127_2438437_3	404589.Anae109_3723	1.482e-128	440.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,2YTTU@29|Myxococcales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
REGS1_k127_2438437_12	305900.GV64_11420	6.598e-29	126.0	290RU@1|root,2ZNDZ@2|Bacteria,1P98B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2438437_21	237368.SCABRO_03655	5.93e-05	55.0	COG3668@1|root,COG3668@2|Bacteria,2J4NM@203682|Planctomycetes	203682|Planctomycetes	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_2438437_14	768671.ThimaDRAFT_2837	8.151e-21	95.0	COG2161@1|root,COG2161@2|Bacteria,1NM8Y@1224|Proteobacteria	1224|Proteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_2438437_7	109760.SPPG_05784T0	3.828e-67	242.0	2BN73@1|root,2S1NQ@2759|Eukaryota,3A55Y@33154|Opisthokonta,3P4MH@4751|Fungi	4751|Fungi	S	Allomyces macrogynus ATCC 38327	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
REGS1_k127_2438437_19	675814.VIC_003624	3.309e-11	74.0	arCOG13953@1|root,2ZC7Q@2|Bacteria,1P0IH@1224|Proteobacteria,1T14Q@1236|Gammaproteobacteria,1Y30T@135623|Vibrionales	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2438437_4	1173020.Cha6605_0806	8.734e-127	415.0	COG0604@1|root,COG0604@2|Bacteria,1G0N4@1117|Cyanobacteria	1117|Cyanobacteria	C	NADPH quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
REGS1_k127_2438437_5	290397.Adeh_3808	8.878e-68	234.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,42TV9@68525|delta/epsilon subdivisions,2WNAN@28221|Deltaproteobacteria,2YV81@29|Myxococcales	28221|Deltaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
REGS1_k127_2438437_17	404589.Anae109_0467	1.206e-17	89.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	pilG	-	-	ko:K02657,ko:K03413	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_2438437_15	1192034.CAP_4270	3.648e-20	107.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42QZV@68525|delta/epsilon subdivisions,2WN5Z@28221|Deltaproteobacteria,2YUTI@29|Myxococcales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
REGS1_k127_2438437_6	404589.Anae109_3533	2.747e-67	259.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_2438437_16	765910.MARPU_07120	2.471e-18	101.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,1RMFK@1236|Gammaproteobacteria,1WW26@135613|Chromatiales	135613|Chromatiales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
REGS1_k127_2438437_9	378806.STAUR_1865	2.852e-46	192.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,4394T@68525|delta/epsilon subdivisions,2X4AZ@28221|Deltaproteobacteria,2YYN8@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
REGS1_k127_2438437_13	1121124.JNIX01000010_gene768	3.064e-21	103.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2UA4W@28211|Alphaproteobacteria,2KH44@204458|Caulobacterales	204458|Caulobacterales	T	PFAM response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
REGS1_k127_2438437_0	404589.Anae109_3925	5.033e-234	782.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42R96@68525|delta/epsilon subdivisions,2WMVV@28221|Deltaproteobacteria,2YXAR@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
REGS1_k127_2438437_22	1433126.BN938_1134	0.0007828	53.0	29YEU@1|root,30K9F@2|Bacteria,4PC85@976|Bacteroidetes,2G1XZ@200643|Bacteroidia,22VP3@171550|Rikenellaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2438437_1	404589.Anae109_3923	5.165e-223	719.0	COG0827@1|root,COG0827@2|Bacteria	2|Bacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	DUF3560,Eco57I,Helicase_C,N6_Mtase
REGS1_k127_2438437_8	1144275.COCOR_07007	8.917e-53	200.0	COG2173@1|root,COG2173@2|Bacteria,1N3QY@1224|Proteobacteria,42TQ8@68525|delta/epsilon subdivisions,2WNK8@28221|Deltaproteobacteria,2Z1HD@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
REGS1_k127_2438437_20	395965.Msil_1876	4.683e-05	51.0	COG1487@1|root,COG1487@2|Bacteria,1MZB6@1224|Proteobacteria,2U9C1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC_2	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
REGS1_k127_2438437_18	1121438.JNJA01000010_gene1939	1.12e-15	78.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria,2M8KT@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
REGS1_k127_2453205_1	1242864.D187_002933	1.352e-33	134.0	COG0454@1|root,COG0456@2|Bacteria,1Q9M5@1224|Proteobacteria,434GJ@68525|delta/epsilon subdivisions,2WYTX@28221|Deltaproteobacteria,2Z0KV@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_2453205_3	1408254.T458_00760	4.056e-07	63.0	2EQFB@1|root,33I1B@2|Bacteria,1W5WB@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2453205_0	290397.Adeh_3401	1.558e-132	431.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
REGS1_k127_2453205_2	290397.Adeh_3401	7.297e-33	130.0	COG0840@1|root,COG0840@2|Bacteria	2|Bacteria	NT	transmembrane signaling receptor activity	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
REGS1_k127_2482156_1	1242864.D187_009771	1.513e-115	414.0	COG0457@1|root,COG0457@2|Bacteria	1242864.D187_009771|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2482156_2	404589.Anae109_2080	4.37e-62	240.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WN3N@28221|Deltaproteobacteria,2YVHP@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
REGS1_k127_2482156_0	404589.Anae109_2078	1.786e-242	755.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2YTVW@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_2482156_3	1041159.AZUW01000033_gene2464	1.769e-51	186.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria,4BCCP@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_2488999_0	632335.Calkr_1515	2.428e-40	169.0	COG5263@1|root,COG5263@2|Bacteria,1V2GT@1239|Firmicutes,24EI0@186801|Clostridia,42IJP@68295|Thermoanaerobacterales	186801|Clostridia	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1,WG_beta_rep
REGS1_k127_2488999_2	1254432.SCE1572_24340	3.472e-26	127.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_2488999_1	1206729.BAFZ01000002_gene298	2.099e-33	140.0	COG0596@1|root,COG0596@2|Bacteria,2IDW0@201174|Actinobacteria,4G0Y2@85025|Nocardiaceae	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	3.1.1.24	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00568	R02991	RC00825	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
REGS1_k127_2488999_4	696281.Desru_0527	1.515e-06	60.0	COG1246@1|root,COG1246@2|Bacteria	2|Bacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	ywlB	-	1.20.4.1,2.3.1.1	ko:K00537,ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,ArsC,C_GCAxxG_C_C
REGS1_k127_2488999_5	1293054.HSACCH_01538	0.0007551	51.0	2C91C@1|root,30CC5@2|Bacteria,1V1Z2@1239|Firmicutes,24HJH@186801|Clostridia	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
REGS1_k127_2488999_3	1123248.KB893316_gene4659	7.993e-10	60.0	COG2249@1|root,COG2249@2|Bacteria,4NMQV@976|Bacteroidetes,1IRT3@117747|Sphingobacteriia	976|Bacteroidetes	S	Flavodoxin-like fold	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
REGS1_k127_2493255_3	2074.JNYD01000004_gene4943	0.000464	52.0	COG2353@1|root,COG2353@2|Bacteria,2GJFT@201174|Actinobacteria,4DYS7@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,YceI
REGS1_k127_2493255_1	292459.STH638	3.695e-30	127.0	COG0778@1|root,COG0778@2|Bacteria,1V2D6@1239|Firmicutes,25B91@186801|Clostridia	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_2493255_0	215803.DB30_4432	4.775e-32	141.0	COG0764@1|root,COG0764@2|Bacteria	2|Bacteria	I	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	fabZ	-	3.5.1.108,4.2.1.59	ko:K02372,ko:K16363	ko00061,ko00540,ko00780,ko01100,ko01212,map00061,map00540,map00780,map01100,map01212	M00060,M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965,R07764,R10117,R10121	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
REGS1_k127_2493255_2	1187851.A33M_2132	2.437e-12	80.0	COG0304@1|root,COG0304@2|Bacteria,1MXZ7@1224|Proteobacteria,2TVEB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	synthase	fabF2	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ketoacyl-synt
REGS1_k127_2510098_2	290397.Adeh_1643	3.157e-94	311.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJEI@28221|Deltaproteobacteria,2Z2X3@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
REGS1_k127_2510098_0	290397.Adeh_1642	1.064e-245	763.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,2YWXC@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
REGS1_k127_2510098_6	215803.DB30_1205	4.935e-09	59.0	2B8AJ@1|root,321J6@2|Bacteria,1QAKI@1224|Proteobacteria,43E1Z@68525|delta/epsilon subdivisions,2WZGI@28221|Deltaproteobacteria,2Z23S@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2510098_4	290397.Adeh_1641	5.449e-48	175.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
REGS1_k127_2510098_1	290397.Adeh_1640	1.789e-164	524.0	COG1494@1|root,COG1494@2|Bacteria,1MUB1@1224|Proteobacteria,42M34@68525|delta/epsilon subdivisions,2WKJ6@28221|Deltaproteobacteria,2YX5K@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	-	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
REGS1_k127_2510098_5	404589.Anae109_2175	1.909e-37	153.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
REGS1_k127_2514700_5	404589.Anae109_0494	4.47e-12	67.0	2A107@1|root,30P5K@2|Bacteria,1QBFU@1224|Proteobacteria,435GC@68525|delta/epsilon subdivisions,2WZTV@28221|Deltaproteobacteria,2Z2QW@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich CPXCG	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPXG
REGS1_k127_2514700_3	404589.Anae109_0495	3.263e-111	365.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QU3@68525|delta/epsilon subdivisions,2WMTF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_2514700_0	404589.Anae109_0496	4.655e-311	979.0	COG0577@1|root,COG0577@2|Bacteria,1RC4T@1224|Proteobacteria,42QZ6@68525|delta/epsilon subdivisions,2WMU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
REGS1_k127_2514700_1	404589.Anae109_0497	2.957e-194	624.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42NUK@68525|delta/epsilon subdivisions,2WJTJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_2514700_2	404589.Anae109_0498	2.03e-120	412.0	COG2834@1|root,COG2834@2|Bacteria,1R5CY@1224|Proteobacteria,42PWK@68525|delta/epsilon subdivisions,2WKW1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
REGS1_k127_2514700_4	290397.Adeh_3935	4.236e-22	103.0	2DNEA@1|root,32X2Y@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2529072_0	469383.Cwoe_4272	1.405e-18	93.0	COG1595@1|root,COG1595@2|Bacteria,2HF4Y@201174|Actinobacteria,4CRJB@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_2529072_1	1317124.DW2_01640	9.131e-07	62.0	COG3595@1|root,COG3595@2|Bacteria,1QY5M@1224|Proteobacteria,2TXGT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2533188_1	404589.Anae109_0963	1.938e-43	171.0	COG3303@1|root,COG3303@2|Bacteria	2|Bacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2
REGS1_k127_2533188_2	290397.Adeh_0918	4.396e-37	145.0	290MS@1|root,2ZNA5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2533188_0	290397.Adeh_0919	3.727e-139	454.0	2ANJD@1|root,31DIF@2|Bacteria,1QAU4@1224|Proteobacteria,43E3V@68525|delta/epsilon subdivisions,2WZMZ@28221|Deltaproteobacteria,2Z0Q6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2533188_3	391625.PPSIR1_28701	7.671e-05	46.0	COG2010@1|root,COG2010@2|Bacteria,1N7I9@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2537080_4	1168289.AJKI01000007_gene152	7.453e-22	112.0	COG0477@1|root,COG2814@2|Bacteria,4NI1T@976|Bacteroidetes,2FRJG@200643|Bacteroidia,3XKJI@558415|Marinilabiliaceae	976|Bacteroidetes	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_2537080_0	452637.Oter_3095	1.665e-144	482.0	COG1164@1|root,COG1164@2|Bacteria,46UYD@74201|Verrucomicrobia,3K7VF@414999|Opitutae	414999|Opitutae	E	Oligopeptidase F	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
REGS1_k127_2537080_1	290397.Adeh_3961	9.51e-96	333.0	COG3850@1|root,COG3850@2|Bacteria,1N013@1224|Proteobacteria,42Z7D@68525|delta/epsilon subdivisions,2WURU@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
REGS1_k127_2537080_3	404589.Anae109_2412	2.847e-62	222.0	2ESNI@1|root,33K73@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
REGS1_k127_2537080_2	290397.Adeh_3940	3.333e-79	267.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,2YW3V@29|Myxococcales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
REGS1_k127_2539786_11	404589.Anae109_3421	1.679e-58	210.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria,2YUR2@29|Myxococcales	28221|Deltaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
REGS1_k127_2539786_0	404589.Anae109_3422	1.45e-152	493.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria,2YV7J@29|Myxococcales	28221|Deltaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
REGS1_k127_2539786_14	1415778.JQMM01000001_gene2084	2.041e-13	78.0	2DU2E@1|root,33NN7@2|Bacteria,1P5P1@1224|Proteobacteria,1SV3F@1236|Gammaproteobacteria,1JBM0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2539786_7	290397.Adeh_3360	3.527e-81	275.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2YVIB@29|Myxococcales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
REGS1_k127_2539786_4	404589.Anae109_3425	2.934e-113	369.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,42NEX@68525|delta/epsilon subdivisions,2WJ1Y@28221|Deltaproteobacteria,2YUXF@29|Myxococcales	28221|Deltaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
REGS1_k127_2539786_5	404589.Anae109_3426	4.043e-94	324.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2Z13M@29|Myxococcales	28221|Deltaproteobacteria	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
REGS1_k127_2539786_1	404589.Anae109_3427	4.926e-145	466.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,42MC3@68525|delta/epsilon subdivisions,2WK3M@28221|Deltaproteobacteria,2YUW8@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
REGS1_k127_2539786_9	1278073.MYSTI_05277	1.426e-63	234.0	COG3746@1|root,COG3746@2|Bacteria,1N2GT@1224|Proteobacteria,42W61@68525|delta/epsilon subdivisions,2WRSI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
REGS1_k127_2539786_8	483219.LILAB_17800	6.079e-64	229.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,431UR@68525|delta/epsilon subdivisions,2WWZQ@28221|Deltaproteobacteria,2YU65@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
REGS1_k127_2539786_3	290397.Adeh_3364	8.295e-114	370.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
REGS1_k127_2539786_6	404589.Anae109_3430	1.296e-81	297.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2YVHZ@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
REGS1_k127_2539786_13	404589.Anae109_3431	2.018e-41	171.0	COG2137@1|root,COG2137@2|Bacteria	2|Bacteria	S	regulation of DNA repair	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
REGS1_k127_2539786_2	290397.Adeh_3368	1.067e-128	415.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_2578864_0	290397.Adeh_3085	5.413e-266	822.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2YUTM@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the argininosuccinate synthase family. Type	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
REGS1_k127_2578864_2	401053.AciPR4_2332	1.219e-36	161.0	COG2374@1|root,COG4932@1|root,COG5276@1|root,COG2374@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,3Y8ZJ@57723|Acidobacteria	57723|Acidobacteria	M	Protein of unknown function (DUF3494)	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494
REGS1_k127_2578864_1	290397.Adeh_2533	1.415e-115	374.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2YTWY@29|Myxococcales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
REGS1_k127_2581697_2	290397.Adeh_1520	2.374e-123	396.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
REGS1_k127_2581697_1	404589.Anae109_2291	1.793e-142	462.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
REGS1_k127_2581697_4	404589.Anae109_2290	1.324e-79	267.0	COG0537@1|root,COG0537@2|Bacteria,1RHYQ@1224|Proteobacteria,42SEG@68525|delta/epsilon subdivisions,2WPFW@28221|Deltaproteobacteria,2Z10H@29|Myxococcales	28221|Deltaproteobacteria	FG	Protein similar to CwfJ C-terminus 1	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	CwfJ_C_1,HIT
REGS1_k127_2581697_3	290397.Adeh_1523	4.146e-107	358.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,42UW4@68525|delta/epsilon subdivisions,2WR5T@28221|Deltaproteobacteria,2Z2AR@29|Myxococcales	28221|Deltaproteobacteria	G	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	-	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2,TPR_7,TPR_8
REGS1_k127_2581697_0	290397.Adeh_1524	8.119e-320	988.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2YWMT@29|Myxococcales	28221|Deltaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
REGS1_k127_2581697_5	404589.Anae109_2287	7.28e-22	101.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,42X25@68525|delta/epsilon subdivisions,2WSPI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Sporulation related domain	agmI	-	-	-	-	-	-	-	-	-	-	-	SPOR
REGS1_k127_2602545_3	1379270.AUXF01000005_gene717	5.493e-09	68.0	COG2146@1|root,COG2146@2|Bacteria,1ZUK1@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
REGS1_k127_2602545_0	246197.MXAN_4102	1.17e-107	361.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NSM@68525|delta/epsilon subdivisions,2WJXQ@28221|Deltaproteobacteria,2YYRI@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_2602545_1	1254432.SCE1572_08920	8.947e-74	267.0	COG1277@1|root,COG1277@2|Bacteria,1Q27K@1224|Proteobacteria,437U7@68525|delta/epsilon subdivisions,2X33U@28221|Deltaproteobacteria,2YU3F@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K19341	ko02010,map02010	M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.132.2	-	-	-
REGS1_k127_2602545_2	1278073.MYSTI_03820	2.185e-35	154.0	2BJUZ@1|root,32E77@2|Bacteria,1QTN5@1224|Proteobacteria,43803@68525|delta/epsilon subdivisions,2X3A1@28221|Deltaproteobacteria,2YV23@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2614612_2	296591.Bpro_4325	1.221e-05	55.0	COG3266@1|root,COG3266@2|Bacteria,1QYJ8@1224|Proteobacteria,2WHG3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2614612_0	404589.Anae109_0478	8.967e-310	970.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,2YZII@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
REGS1_k127_2614612_1	404589.Anae109_0479	7.293e-40	152.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
REGS1_k127_2619172_3	290397.Adeh_1625	2.339e-189	595.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_2619172_6	290397.Adeh_1624	1.165e-86	293.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
REGS1_k127_2619172_8	404589.Anae109_2190	3.832e-80	279.0	COG3012@1|root,COG3012@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07039	-	-	-	-	ko00000	-	-	-	DUF1186,SEC-C,UPF0149
REGS1_k127_2619172_2	290397.Adeh_1620	1.674e-197	619.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria,2YV05@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
REGS1_k127_2619172_1	290397.Adeh_1619	7.457e-217	696.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2YU2Z@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
REGS1_k127_2619172_4	290397.Adeh_1618	5.286e-163	527.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,2YU78@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_2619172_9	290397.Adeh_1617	8.074e-70	243.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,42S2E@68525|delta/epsilon subdivisions,2WMT9@28221|Deltaproteobacteria,2YVDA@29|Myxococcales	28221|Deltaproteobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
REGS1_k127_2619172_5	404589.Anae109_2196	3.069e-96	336.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2YV8J@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
REGS1_k127_2619172_0	290397.Adeh_1614	0.0	1054.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2YUH4@29|Myxococcales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
REGS1_k127_2619172_7	404589.Anae109_2198	7.507e-86	288.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
REGS1_k127_2648429_0	290397.Adeh_1310	0.0	1241.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,2YXGJ@29|Myxococcales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
REGS1_k127_2648429_1	483219.LILAB_23245	5.918e-41	153.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	embR	GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	BTAD,DUF3662,FHA,Trans_reg_C,Yop-YscD_cpl
REGS1_k127_26711_12	1089548.KI783301_gene2449	1.978e-16	81.0	COG1396@1|root,COG1396@2|Bacteria,1U5FN@1239|Firmicutes,4HZGA@91061|Bacilli	91061|Bacilli	K	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
REGS1_k127_26711_11	351348.Maqu_2522	1.682e-23	116.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,468AF@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
REGS1_k127_26711_1	404589.Anae109_3565	5.423e-242	760.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria,2YX7S@29|Myxococcales	28221|Deltaproteobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
REGS1_k127_26711_0	290397.Adeh_0174	8.41e-273	850.0	COG3083@1|root,COG3083@2|Bacteria,1MX6X@1224|Proteobacteria,42R7V@68525|delta/epsilon subdivisions,2WN3A@28221|Deltaproteobacteria,2Z3GU@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3413)	-	-	-	ko:K07014	-	-	-	-	ko00000	-	-	-	DUF3413,Sulfatase
REGS1_k127_26711_9	96561.Dole_2620	2.231e-67	244.0	2A8H0@1|root,30XJ2@2|Bacteria,1REE0@1224|Proteobacteria,42SSU@68525|delta/epsilon subdivisions,2WUYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_26711_4	404589.Anae109_3562	3.165e-182	575.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,2Z35M@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
REGS1_k127_26711_3	290397.Adeh_3452	4.563e-183	579.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YUQI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_26711_13	2002.JOEQ01000020_gene7083	2.653e-08	66.0	COG3266@1|root,COG3266@2|Bacteria,2GQ3D@201174|Actinobacteria,4EK9A@85012|Streptosporangiales	201174|Actinobacteria	S	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
REGS1_k127_26711_6	1403819.BATR01000040_gene1181	4.494e-104	381.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,46WM8@74201|Verrucomicrobia,2IV4E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,TPR_16,Transglut_core
REGS1_k127_26711_2	404589.Anae109_3556	7.171e-198	622.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,2YV33@29|Myxococcales	28221|Deltaproteobacteria	E	Threonine dehydratase	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP,Thr_dehydrat_C
REGS1_k127_26711_8	290397.Adeh_3447	2.451e-77	265.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_26711_7	290397.Adeh_3446	4.863e-87	301.0	COG0730@1|root,COG0730@2|Bacteria,1Q55W@1224|Proteobacteria,42VG9@68525|delta/epsilon subdivisions,2WRT4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
REGS1_k127_26711_5	404589.Anae109_2646	3.595e-130	422.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Pyr_redox_3
REGS1_k127_2683714_1	338969.Rfer_2434	1.881e-23	104.0	COG2249@1|root,COG2249@2|Bacteria,1RAP1@1224|Proteobacteria,2VRHH@28216|Betaproteobacteria,4AJ8V@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavodoxin-like fold	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
REGS1_k127_2683714_2	1173028.ANKO01000199_gene3578	3.438e-23	101.0	COG1669@1|root,COG1669@2|Bacteria,1G7R5@1117|Cyanobacteria,1HCID@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
REGS1_k127_2683714_5	314230.DSM3645_16855	1.015e-15	81.0	COG1396@1|root,COG1396@2|Bacteria,2J1AI@203682|Planctomycetes	203682|Planctomycetes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2683714_3	211165.AJLN01000117_gene2961	4.817e-20	96.0	COG4679@1|root,COG4679@2|Bacteria,1G6N5@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
REGS1_k127_2683714_6	1121938.AUDY01000007_gene2501	9.344e-07	54.0	2DR03@1|root,339MB@2|Bacteria,1VK6Y@1239|Firmicutes,4HR34@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2683714_4	398512.JQKC01000006_gene704	2.503e-19	92.0	2E5T4@1|root,330HF@2|Bacteria,1VGGW@1239|Firmicutes,24RKP@186801|Clostridia,3WK7D@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2683714_0	889378.Spiaf_0116	8.09e-187	608.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2J5ZA@203691|Spirochaetes	203691|Spirochaetes	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
REGS1_k127_2687122_2	404589.Anae109_1771	2.31e-91	327.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WUVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
REGS1_k127_2687122_1	404589.Anae109_3003	2.632e-215	677.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	gabD	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_2687122_0	290397.Adeh_3019	4.104e-252	781.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YU75@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
REGS1_k127_2704052_2	290397.Adeh_1271	9.219e-19	85.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2YVAI@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, CarD family	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
REGS1_k127_2704052_1	404589.Anae109_2497	7.555e-171	549.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
REGS1_k127_2704052_3	215803.DB30_6749	9.343e-06	59.0	2A4HI@1|root,30T3W@2|Bacteria,1PCRH@1224|Proteobacteria,438JF@68525|delta/epsilon subdivisions,2X25H@28221|Deltaproteobacteria,2YX47@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2704052_0	290397.Adeh_1273	3.936e-232	735.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,2YUIX@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
REGS1_k127_2711689_3	404589.Anae109_0149	2.67e-49	176.0	COG0745@1|root,COG0745@2|Bacteria	404589.Anae109_0149|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2711689_5	1127134.NOCYR_3208	6.21e-34	139.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria,4FZ7T@85025|Nocardiaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
REGS1_k127_2711689_7	1220534.B655_2308	1e-25	114.0	arCOG02576@1|root,arCOG02576@2157|Archaea	2157|Archaea	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_2711689_6	1408473.JHXO01000004_gene1	9.38e-31	133.0	COG2249@1|root,COG2249@2|Bacteria	2|Bacteria	K	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red,Flavodoxin_2
REGS1_k127_2711689_2	316067.Geob_1189	1.44e-97	336.0	COG4887@1|root,COG4887@2|Bacteria,1RKM1@1224|Proteobacteria,42SU2@68525|delta/epsilon subdivisions,2WP4U@28221|Deltaproteobacteria,43UDW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1847
REGS1_k127_2711689_0	290397.Adeh_0141	1.584e-173	554.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
REGS1_k127_2711689_4	290397.Adeh_0140	1.229e-43	165.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	MA20_09445	-	-	ko:K09017,ko:K18301	-	M00642	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	TetR_C_11,TetR_N
REGS1_k127_2711689_1	404589.Anae109_0143	9.051e-172	554.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,42REB@68525|delta/epsilon subdivisions,2WNWD@28221|Deltaproteobacteria,2YUH8@29|Myxococcales	28221|Deltaproteobacteria	C	FAD dependent oxidoreductase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
REGS1_k127_2741664_15	404589.Anae109_1527	2.622e-23	102.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,NPCBM_assoc,PEGA
REGS1_k127_2741664_1	290397.Adeh_2345	1.023e-267	836.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2YWT8@29|Myxococcales	28221|Deltaproteobacteria	I	Amp-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
REGS1_k127_2741664_13	404589.Anae109_1530	2.311e-25	110.0	COG3437@1|root,COG3437@2|Bacteria,1QYG6@1224|Proteobacteria,43CCB@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_2741664_12	290397.Adeh_2343	2.158e-37	146.0	COG3255@1|root,COG3255@2|Bacteria,1PWYZ@1224|Proteobacteria,432A7@68525|delta/epsilon subdivisions,2WXR1@28221|Deltaproteobacteria,2YW4M@29|Myxococcales	28221|Deltaproteobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
REGS1_k127_2741664_8	290397.Adeh_2340	2.821e-117	391.0	COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria,2YYH9@29|Myxococcales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2741664_7	404589.Anae109_1535	2.324e-130	422.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WQ7S@28221|Deltaproteobacteria,2YTZ9@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
REGS1_k127_2741664_10	290397.Adeh_2338	1.521e-75	287.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
REGS1_k127_2741664_9	290397.Adeh_2337	3.917e-103	354.0	COG1108@1|root,COG1108@2|Bacteria,1Q1G9@1224|Proteobacteria,4378R@68525|delta/epsilon subdivisions,2X2BN@28221|Deltaproteobacteria,2YX1Q@29|Myxococcales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
REGS1_k127_2741664_16	644107.SL1157_0518	6.27e-09	65.0	2DREZ@1|root,33BFB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2741664_14	552811.Dehly_0982	2.626e-24	113.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K02660,ko:K11525	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,EAL,GAF,GGDEF,HAMP,MCPsignal,PAS_3,PAS_4,PAS_7,dCache_1
REGS1_k127_2741664_11	290397.Adeh_0288	1.599e-38	149.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	citB	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	GerE
REGS1_k127_2741664_3	290397.Adeh_0479	3.63e-174	554.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
REGS1_k127_2741664_5	290397.Adeh_0480	1.905e-139	449.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42S59@68525|delta/epsilon subdivisions,2WNGW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hybA	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,TAT_signal
REGS1_k127_2741664_6	290397.Adeh_0342	4.812e-135	437.0	COG1575@1|root,COG1575@2|Bacteria	2|Bacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iECH74115_1262.ECH74115_5387,iG2583_1286.G2583_4737	UbiA
REGS1_k127_2741664_2	404589.Anae109_0567	4.12e-190	608.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WIRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
REGS1_k127_2741664_0	404589.Anae109_0568	0.0	1559.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,2YX3T@29|Myxococcales	28221|Deltaproteobacteria	U	MMPL family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
REGS1_k127_2741664_4	404589.Anae109_0569	2.141e-167	534.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42NHV@68525|delta/epsilon subdivisions,2WJBA@28221|Deltaproteobacteria,2YZKZ@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
REGS1_k127_2745461_3	404589.Anae109_2993	8.206e-29	117.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42P3Y@68525|delta/epsilon subdivisions,2WJG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
REGS1_k127_2745461_1	290397.Adeh_3013	2.889e-274	855.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2YY6V@29|Myxococcales	28221|Deltaproteobacteria	C	Pyruvate flavodoxin ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR,POR_N
REGS1_k127_2745461_2	290397.Adeh_1534	5.169e-48	178.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,43C2Q@68525|delta/epsilon subdivisions,2WSJ0@28221|Deltaproteobacteria,2YVH1@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	-	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4
REGS1_k127_2745461_0	1192034.CAP_6022	9.35e-280	874.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria,2YYGK@29|Myxococcales	28221|Deltaproteobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
REGS1_k127_2745461_4	671143.DAMO_0413	5.035e-27	112.0	COG2156@1|root,COG2156@2|Bacteria,2NPIZ@2323|unclassified Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iEcE24377_1341.EcE24377A_0722,ic_1306.c0781	KdpC
REGS1_k127_2746926_5	1205680.CAKO01000006_gene3172	4.83e-35	147.0	COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2TR5B@28211|Alphaproteobacteria,2JPY3@204441|Rhodospirillales	204441|Rhodospirillales	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_2746926_1	404589.Anae109_0623	2.531e-108	357.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
REGS1_k127_2746926_2	404589.Anae109_0622	3.4e-86	292.0	COG4493@1|root,COG4493@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1054)	yktB	-	-	-	-	-	-	-	-	-	-	-	DUF1054
REGS1_k127_2746926_0	404589.Anae109_0620	1.263e-192	629.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42RPW@68525|delta/epsilon subdivisions,2WK10@28221|Deltaproteobacteria,2Z2WV@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_2
REGS1_k127_2746926_3	290397.Adeh_0576	1.857e-75	264.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YUUX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_2762730_1	404589.Anae109_1028	1.287e-92	328.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2WKBP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,Sulfatase
REGS1_k127_2762730_0	290397.Adeh_0153	7.025e-259	806.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2YY2C@29|Myxococcales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
REGS1_k127_281499_0	269799.Gmet_1728	8.392e-231	722.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,42KZZ@68525|delta/epsilon subdivisions,2WJWV@28221|Deltaproteobacteria,43SQT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Glu Leu Phe Val dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH,ELFV_dehydrog
REGS1_k127_282327_4	215803.DB30_3672	8.456e-05	46.0	2AMKK@1|root,31CGI@2|Bacteria,1PDD0@1224|Proteobacteria,43918@68525|delta/epsilon subdivisions,2X46K@28221|Deltaproteobacteria,2YYCX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_282327_2	290397.Adeh_3932	1.045e-43	164.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,42VVC@68525|delta/epsilon subdivisions,2WRH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
REGS1_k127_282327_1	404589.Anae109_1635	1.928e-173	556.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,42PR8@68525|delta/epsilon subdivisions,2WK8J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_282327_0	290397.Adeh_3930	0.0	1238.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria,2YXS2@29|Myxococcales	28221|Deltaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
REGS1_k127_282327_3	290397.Adeh_3927	1.5e-06	51.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria,2YZDA@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_2823388_0	290397.Adeh_0787	1.212e-275	860.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,42MD4@68525|delta/epsilon subdivisions,2WJ7Z@28221|Deltaproteobacteria,2YU2M@29|Myxococcales	28221|Deltaproteobacteria	L	ATP-dependent helicase HrpB	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
REGS1_k127_2823388_1	1121939.L861_04745	5.335e-56	211.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,1S3T8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
REGS1_k127_2823388_2	1150626.PHAMO_380077	1.771e-06	49.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,2UH5E@28211|Alphaproteobacteria,2JU1M@204441|Rhodospirillales	204441|Rhodospirillales	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
REGS1_k127_2829504_5	404589.Anae109_2210	2.486e-38	156.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria	1224|Proteobacteria	M	soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)	slt	GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	iETEC_1333.ETEC_4747,iPC815.YPO0452	SLT,SLT_L
REGS1_k127_2829504_1	290397.Adeh_1604	5.719e-113	386.0	COG2340@1|root,COG2340@2|Bacteria,1REVB@1224|Proteobacteria,4386P@68525|delta/epsilon subdivisions,2X3GI@28221|Deltaproteobacteria,2YW01@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
REGS1_k127_2829504_7	290397.Adeh_1605	5.397e-22	98.0	COG5512@1|root,COG5512@2|Bacteria	2|Bacteria	L	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
REGS1_k127_2829504_0	290397.Adeh_1606	1.228e-139	458.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,42WNA@68525|delta/epsilon subdivisions,2WRKM@28221|Deltaproteobacteria,2YUJ7@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
REGS1_k127_2829504_2	290397.Adeh_1607	4.928e-94	310.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,42UKS@68525|delta/epsilon subdivisions,2WQV2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
REGS1_k127_2829504_3	404589.Anae109_2204	8.778e-62	214.0	COG0526@1|root,COG0526@2|Bacteria,1QVCY@1224|Proteobacteria,43BX7@68525|delta/epsilon subdivisions,2X780@28221|Deltaproteobacteria,2Z3DU@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	trx	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_2829504_4	290397.Adeh_1610	6.398e-60	214.0	COG0468@1|root,COG0468@2|Bacteria	2|Bacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360	-	ko:K03553,ko:K14160	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
REGS1_k127_2832744_0	700598.Niako_5517	1.244e-159	539.0	COG0841@1|root,COG0841@2|Bacteria,4NDZG@976|Bacteroidetes,1IPQ1@117747|Sphingobacteriia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_2832744_3	1123256.KB907941_gene113	9.505e-56	209.0	COG0845@1|root,COG0845@2|Bacteria,1R443@1224|Proteobacteria,1S3AT@1236|Gammaproteobacteria,1X6AV@135614|Xanthomonadales	135614|Xanthomonadales	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
REGS1_k127_2832744_5	1206741.BAFX01000206_gene345	3.919e-34	147.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria,4FZ7T@85025|Nocardiaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
REGS1_k127_2832744_2	1121022.ABENE_08175	1.211e-66	239.0	COG1864@1|root,COG3591@1|root,COG1864@2|Bacteria,COG3591@2|Bacteria,1QSGF@1224|Proteobacteria,2TTI7@28211|Alphaproteobacteria,2KHA4@204458|Caulobacterales	204458|Caulobacterales	EF	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS,Trypsin_2
REGS1_k127_2832744_1	1101189.AQUO01000003_gene3653	2.256e-69	256.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2U4GD@28211|Alphaproteobacteria,2PWKX@265|Paracoccus	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Peptidase_S8
REGS1_k127_2832744_7	1128421.JAGA01000002_gene668	1.921e-23	116.0	29DKV@1|root,300IP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C25
REGS1_k127_2832744_4	68170.KL590530_gene11452	6.16e-41	160.0	2DI0V@1|root,301MZ@2|Bacteria,2H2A6@201174|Actinobacteria,4E9XX@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2832744_6	994573.T472_0209620	1.159e-28	130.0	COG2159@1|root,COG2159@2|Bacteria,1W49D@1239|Firmicutes,254HV@186801|Clostridia	186801|Clostridia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
REGS1_k127_2834654_0	290397.Adeh_0686	5.507e-290	911.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2YUDZ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
REGS1_k127_2834654_1	290397.Adeh_0685	1.931e-63	246.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YUKY@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_2853537_2	335283.Neut_2196	9.539e-29	119.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,2VU4X@28216|Betaproteobacteria,372W6@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
REGS1_k127_2853537_0	485917.Phep_3971	8.571e-52	203.0	COG4775@1|root,COG4775@2|Bacteria,4NHNW@976|Bacteroidetes,1IQZB@117747|Sphingobacteriia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
REGS1_k127_2853537_3	1307759.JOMJ01000003_gene1775	1.615e-10	73.0	COG1652@1|root,COG1652@2|Bacteria,1N2HY@1224|Proteobacteria,42URJ@68525|delta/epsilon subdivisions,2WQ66@28221|Deltaproteobacteria,2MC9F@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,LysM
REGS1_k127_2853537_1	290397.Adeh_0395	1.848e-35	139.0	COG3071@1|root,COG3071@2|Bacteria	2|Bacteria	H	HemY protein	-	-	-	ko:K02498,ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	HemY_N,Peptidase_C39_2,TPR_16,TPR_19,TPR_2,TPR_4,TPR_7,TPR_8
REGS1_k127_2870162_1	404589.Anae109_0820	8.59e-136	441.0	COG3173@1|root,COG3173@2|Bacteria,1R8W5@1224|Proteobacteria,42PZM@68525|delta/epsilon subdivisions,2WM50@28221|Deltaproteobacteria,2YXAW@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
REGS1_k127_2870162_4	404589.Anae109_0819	2.365e-51	194.0	COG0529@1|root,COG0529@2|Bacteria,1QTVY@1224|Proteobacteria,434UM@68525|delta/epsilon subdivisions,2WZ5M@28221|Deltaproteobacteria,2Z1DN@29|Myxococcales	28221|Deltaproteobacteria	P	Adenylylsulfate kinase	-	-	2.7.1.25	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R04928	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
REGS1_k127_2870162_0	290397.Adeh_0770	1.831e-282	890.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
REGS1_k127_2870162_2	404589.Anae109_3900	2.924e-77	275.0	2EGEF@1|root,33A6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2923720_4	1129794.C427_4423	1.323e-31	136.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,DUF285,MucBP,SdrD_B
REGS1_k127_2923720_2	290397.Adeh_3820	6.279e-169	541.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42NPR@68525|delta/epsilon subdivisions,2WK7F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	C-terminal AAA-associated domain	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	AAA_assoc_C,ABC_tran
REGS1_k127_2923720_0	290397.Adeh_3819	3.581e-213	676.0	COG4986@1|root,COG4986@2|Bacteria,1MV85@1224|Proteobacteria,42Q3M@68525|delta/epsilon subdivisions,2WK99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
REGS1_k127_2923720_1	290397.Adeh_1251	1.613e-187	602.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,2Z0ZJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2923720_5	404589.Anae109_2515	6.408e-28	114.0	COG0227@1|root,COG0227@2|Bacteria,1PTFN@1224|Proteobacteria,42V1S@68525|delta/epsilon subdivisions,2WR85@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	GO:0003674,GO:0003735,GO:0005198	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
REGS1_k127_2932407_11	404589.Anae109_0881	8.356e-43	168.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,42ST5@68525|delta/epsilon subdivisions,2WPNG@28221|Deltaproteobacteria,2Z2WM@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_2932407_6	404589.Anae109_0880	7.646e-106	358.0	COG0745@1|root,COG0745@2|Bacteria,1Q2S0@1224|Proteobacteria,42S32@68525|delta/epsilon subdivisions,2X5XE@28221|Deltaproteobacteria,2YTZ6@29|Myxococcales	28221|Deltaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_2932407_12	290397.Adeh_2913	2.226e-34	151.0	COG3678@1|root,COG3678@2|Bacteria	2|Bacteria	NPTU	ATP-independent chaperone mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ,Metal_resist
REGS1_k127_2932407_1	290397.Adeh_0830	3.994e-288	908.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YTUY@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
REGS1_k127_2932407_8	443144.GM21_1292	1.922e-53	207.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CCK@68525|delta/epsilon subdivisions,2X7Q6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS_4,PAS_9
REGS1_k127_2932407_5	502025.Hoch_5658	2.073e-129	436.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1R91W@1224|Proteobacteria,42PXP@68525|delta/epsilon subdivisions,2WJJX@28221|Deltaproteobacteria,2YX85@29|Myxococcales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_9
REGS1_k127_2932407_7	404589.Anae109_0865	4.099e-81	276.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
REGS1_k127_2932407_14	69328.PVLB_02290	1.167e-21	105.0	COG1442@1|root,COG1442@2|Bacteria,1N76X@1224|Proteobacteria,1SCUA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2932407_2	290397.Adeh_4274	7.765e-242	779.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WN1C@28221|Deltaproteobacteria,2Z2Y2@29|Myxococcales	28221|Deltaproteobacteria	D	PFAM lipopolysaccharide biosynthesis protein	-	-	-	ko:K16692	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_31,GNVR,Wzz
REGS1_k127_2932407_4	290397.Adeh_4275	1.166e-144	495.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42PM8@68525|delta/epsilon subdivisions,2WM7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
REGS1_k127_2932407_10	404589.Anae109_4430	2.955e-44	172.0	COG0394@1|root,COG0394@2|Bacteria,1N0DZ@1224|Proteobacteria,42VKF@68525|delta/epsilon subdivisions,2WTAM@28221|Deltaproteobacteria,2Z36N@29|Myxococcales	28221|Deltaproteobacteria	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
REGS1_k127_2932407_3	290397.Adeh_4294	5.007e-162	528.0	29SIY@1|root,30DQ4@2|Bacteria	2|Bacteria	S	Capsule assembly protein Wzi	-	-	-	-	-	-	-	-	-	-	-	-	Caps_assemb_Wzi
REGS1_k127_2932407_0	404589.Anae109_0864	1.36e-292	914.0	COG3973@1|root,COG3973@2|Bacteria,1MZQF@1224|Proteobacteria,42UXS@68525|delta/epsilon subdivisions,2WQJ8@28221|Deltaproteobacteria,2YYYK@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2
REGS1_k127_2932407_16	1287276.X752_25555	1.877e-05	56.0	2DPH3@1|root,33224@2|Bacteria,1NE43@1224|Proteobacteria,2V4GT@28211|Alphaproteobacteria,43QQX@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2932407_13	870187.Thini_0338	2.079e-33	137.0	COG1848@1|root,COG1848@2|Bacteria,1MZR2@1224|Proteobacteria,1S97Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
REGS1_k127_2932407_9	1121362.A605_12770	7.933e-47	174.0	arCOG05276@1|root,3195F@2|Bacteria,2IM15@201174|Actinobacteria,22NR3@1653|Corynebacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_29343_0	290397.Adeh_2727	0.0	1427.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
REGS1_k127_29343_1	290397.Adeh_1639	8.862e-20	89.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2Z33F@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
REGS1_k127_2956738_3	290397.Adeh_2592	1.226e-43	180.0	COG3419@1|root,COG5184@1|root,COG3419@2|Bacteria,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
REGS1_k127_2956738_2	290397.Adeh_2593	1.399e-49	183.0	COG0745@1|root,COG0745@2|Bacteria	290397.Adeh_2593|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2956738_1	290397.Adeh_2594	2.886e-106	350.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2Z304@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
REGS1_k127_2956738_0	290397.Adeh_2597	5.89e-190	611.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2YV5P@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_2960562_6	290397.Adeh_2725	2.78e-19	89.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria,2YW1W@29|Myxococcales	28221|Deltaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
REGS1_k127_2960562_4	404589.Anae109_2716	9.657e-130	436.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,2YUR9@29|Myxococcales	28221|Deltaproteobacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
REGS1_k127_2960562_1	290397.Adeh_2723	4.322e-208	670.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_2723|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2960562_2	290397.Adeh_2722	1.499e-180	572.0	COG0457@1|root,COG0457@2|Bacteria,1R64F@1224|Proteobacteria,42Q6D@68525|delta/epsilon subdivisions,2WKT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
REGS1_k127_2960562_3	290397.Adeh_2721	1.536e-170	554.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2YTWI@29|Myxococcales	28221|Deltaproteobacteria	T	PhoH-like protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
REGS1_k127_2960562_0	404589.Anae109_2712	4.234e-269	867.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2YUW7@29|Myxococcales	28221|Deltaproteobacteria	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
REGS1_k127_2960562_5	404589.Anae109_2711	4.125e-44	182.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42TCJ@68525|delta/epsilon subdivisions,2X5PW@28221|Deltaproteobacteria,2Z2ZQ@29|Myxococcales	28221|Deltaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
REGS1_k127_2976122_0	404589.Anae109_0352	1.691e-241	752.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,2YV9Y@29|Myxococcales	28221|Deltaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
REGS1_k127_2976122_1	404589.Anae109_0353	1.041e-209	659.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42KZH@68525|delta/epsilon subdivisions,2WIRM@28221|Deltaproteobacteria,2YUK3@29|Myxococcales	28221|Deltaproteobacteria	E	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
REGS1_k127_2976122_2	404589.Anae109_0354	4.404e-89	296.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2YUVE@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
REGS1_k127_297869_2	404589.Anae109_2508	9.845e-103	351.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
REGS1_k127_297869_5	404589.Anae109_2509	6.27e-85	317.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	AMIN
REGS1_k127_297869_0	290397.Adeh_1258	8.437e-168	537.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2YUTG@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
REGS1_k127_297869_1	290397.Adeh_1257	1.041e-150	494.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,2YU1S@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
REGS1_k127_297869_4	1144275.COCOR_05334	8.34e-96	330.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria,2YWV3@29|Myxococcales	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
REGS1_k127_297869_3	290397.Adeh_1256	1.172e-98	326.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2WT4M@28221|Deltaproteobacteria,2YVRK@29|Myxococcales	28221|Deltaproteobacteria	K	cyclic nucleotide-binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	cNMP_binding
REGS1_k127_297869_6	247490.KSU1_C0803	1.21e-21	98.0	2ED2F@1|root,336ZC@2|Bacteria,2J4H4@203682|Planctomycetes	203682|Planctomycetes	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
REGS1_k127_2989150_4	1232410.KI421412_gene406	4.25e-43	167.0	COG1193@1|root,COG1193@2|Bacteria,1QYV7@1224|Proteobacteria	1224|Proteobacteria	L	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2989150_3	497964.CfE428DRAFT_1844	2.382e-69	259.0	COG2461@1|root,COG4191@1|root,COG2461@2|Bacteria,COG4191@2|Bacteria,46U18@74201|Verrucomicrobia	74201|Verrucomicrobia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS_3,Response_reg
REGS1_k127_2989150_1	404589.Anae109_4410	1.051e-160	513.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,42N4E@68525|delta/epsilon subdivisions,2WUQU@28221|Deltaproteobacteria,2YUE4@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfate ABC transporter, periplasmic sulfate-binding protein	cysP	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
REGS1_k127_2989150_0	404589.Anae109_1639	2.205e-173	565.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria	1224|Proteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511	ABC_tran,TOBE_3
REGS1_k127_2989150_2	404589.Anae109_1640	1.729e-132	428.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,42ND8@68525|delta/epsilon subdivisions,2WN93@28221|Deltaproteobacteria,2YWH9@29|Myxococcales	28221|Deltaproteobacteria	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
REGS1_k127_2992905_2	573413.Spirs_2256	5.649e-193	632.0	28MCF@1|root,2ZAQK@2|Bacteria,2J6HI@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2992905_6	404589.Anae109_4365	1.908e-43	183.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CCK@68525|delta/epsilon subdivisions,2X7Q6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS_4,PAS_9
REGS1_k127_2992905_3	1121920.AUAU01000004_gene737	2.733e-110	369.0	COG0564@1|root,COG0564@2|Bacteria,3Y446@57723|Acidobacteria	57723|Acidobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
REGS1_k127_2992905_1	404589.Anae109_0953	4.142e-205	647.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WJ68@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Multi-haem_cyto
REGS1_k127_2992905_7	593750.Metfor_2084	1.829e-36	153.0	COG1917@1|root,arCOG02992@2157|Archaea,2XZHW@28890|Euryarchaeota,2NAZU@224756|Methanomicrobia	224756|Methanomicrobia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_2992905_4	290397.Adeh_0447	6.773e-62	232.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2992905_5	404589.Anae109_3543	2.145e-61	218.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,42NBZ@68525|delta/epsilon subdivisions,2WJ39@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
REGS1_k127_2992905_9	7668.SPU_000965-tr	2.545e-05	50.0	KOG2813@1|root,KOG2813@2759|Eukaryota,38B75@33154|Opisthokonta,3BBXS@33208|Metazoa,3CSG9@33213|Bilateria	33208|Metazoa	O	Protein SSUH2 homolog	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2992905_0	1165841.SULAR_02118	0.0	1123.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,42MZ4@68525|delta/epsilon subdivisions,2YNF5@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
REGS1_k127_3006856_1	404589.Anae109_2899	1.471e-250	780.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	fadE23	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_3006856_0	404589.Anae109_2898	4.608e-292	907.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2WKRZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Electron transfer flavoprotein-ubiquinone	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
REGS1_k127_3006856_2	404589.Anae109_2897	1.01e-129	439.0	COG2086@1|root,COG2086@2|Bacteria,1R7VY@1224|Proteobacteria,42N0T@68525|delta/epsilon subdivisions,2WKSK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
REGS1_k127_3006856_3	404589.Anae109_2896	4.785e-05	55.0	COG2025@1|root,COG2025@2|Bacteria	2|Bacteria	C	fatty acid beta-oxidation using acyl-CoA dehydrogenase	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Acyl-CoA_dh_1,ETF,ETF_alpha
REGS1_k127_3024262_0	404589.Anae109_4431	3.567e-223	705.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WUE6@28221|Deltaproteobacteria,2YTX9@29|Myxococcales	28221|Deltaproteobacteria	V	Efflux ABC transporter, permease ATP-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_3024262_2	398767.Glov_3032	1.768e-39	152.0	COG4315@1|root,COG4315@2|Bacteria,1MZC6@1224|Proteobacteria,4324Y@68525|delta/epsilon subdivisions,2WY5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
REGS1_k127_3024262_1	765420.OSCT_2454	3.778e-98	324.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria	2|Bacteria	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II,adh_short,adh_short_C2
REGS1_k127_3029918_19	404589.Anae109_2770	1.236e-40	151.0	COG1697@1|root,COG1697@2|Bacteria,1NBFJ@1224|Proteobacteria,4314R@68525|delta/epsilon subdivisions,2WWNC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA topoisomerase VI subunit A	top6A	-	5.99.1.3	ko:K03166	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	TP6A_N
REGS1_k127_3029918_7	296587.XP_002505111.1	2.189e-96	329.0	COG0604@1|root,KOG1198@2759|Eukaryota	2759|Eukaryota	C	oxidoreductase activity	VAT1L	-	2.3.1.85	ko:K00665	ko00061,ko01100,ko01212,ko04152,ko04910,map00061,map01100,map01212,map04152,map04910	M00082,M00083	R01404,R01624,R01626,R01706,R04355,R04428,R04430,R04533,R04534,R04535,R04536,R04537,R04543,R04544,R04566,R04568,R04725,R04726,R04952,R04953,R04954,R04956,R04957,R04959,R04960,R04962,R04963,R04965,R04967,R04968,R04970,R08159	RC00004,RC00014,RC00029,RC00039,RC00052,RC00076,RC00117,RC00120,RC00831,RC01095,RC02727,RC02728,RC02729,RC02857,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
REGS1_k127_3029918_11	215803.DB30_6126	1.104e-82	278.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria,42U2Q@68525|delta/epsilon subdivisions,2WQK9@28221|Deltaproteobacteria,2YW3Q@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
REGS1_k127_3029918_2	290397.Adeh_2837	2.337e-113	371.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,42NY0@68525|delta/epsilon subdivisions,2X3G8@28221|Deltaproteobacteria,2YVYR@29|Myxococcales	28221|Deltaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
REGS1_k127_3029918_16	404589.Anae109_2358	6.966e-64	226.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,43A75@68525|delta/epsilon subdivisions,2X9W3@28221|Deltaproteobacteria,2Z1PF@29|Myxococcales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
REGS1_k127_3029918_23	404589.Anae109_2360	3.587e-30	125.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
REGS1_k127_3029918_8	290397.Adeh_2509	1.151e-95	320.0	COG2952@1|root,COG2952@2|Bacteria,1QJIU@1224|Proteobacteria,43826@68525|delta/epsilon subdivisions,2X3CC@28221|Deltaproteobacteria,2YVDW@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF507)	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
REGS1_k127_3029918_14	404589.Anae109_1363	1.618e-72	258.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WS8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
REGS1_k127_3029918_5	290397.Adeh_2503	1.756e-98	326.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2YZQW@29|Myxococcales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
REGS1_k127_3029918_12	290397.Adeh_2502	1.026e-77	264.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,2YVJK@29|Myxococcales	28221|Deltaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
REGS1_k127_3029918_4	215803.DB30_6730	1.55e-101	342.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q7A@68525|delta/epsilon subdivisions,2WM81@28221|Deltaproteobacteria,2YW8C@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF
REGS1_k127_3029918_1	404589.Anae109_1367	2.166e-136	452.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	peptidyl-prolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_3029918_6	290397.Adeh_2500	4.603e-98	332.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42UFT@68525|delta/epsilon subdivisions,2WR3P@28221|Deltaproteobacteria,2Z2Z3@29|Myxococcales	28221|Deltaproteobacteria	D	Involved in formation and maintenance of cell shape	-	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
REGS1_k127_3029918_0	290397.Adeh_2498	4.781e-302	938.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2YU5Y@29|Myxococcales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
REGS1_k127_3029918_3	215803.DB30_6724	2.151e-109	366.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2YUT8@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
REGS1_k127_3029918_21	338969.Rfer_0254	7.758e-35	144.0	COG0457@1|root,COG0457@2|Bacteria,1NYJF@1224|Proteobacteria	1224|Proteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3029918_18	404589.Anae109_1372	1.664e-46	174.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,2YVHU@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_3029918_17	290397.Adeh_2495	7.755e-51	186.0	2A21P@1|root,30QBQ@2|Bacteria,1Q2MF@1224|Proteobacteria,43882@68525|delta/epsilon subdivisions,2X3HT@28221|Deltaproteobacteria,2YW5S@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3029918_10	404589.Anae109_1373	3.005e-89	311.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,2Z3NJ@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_3029918_9	404589.Anae109_1374	7.689e-93	327.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2YWEM@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
REGS1_k127_3032787_0	290397.Adeh_3989	2.445e-146	474.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,42RD4@68525|delta/epsilon subdivisions,2WN11@28221|Deltaproteobacteria,2YU83@29|Myxococcales	28221|Deltaproteobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_3032787_2	1380387.JADM01000002_gene1910	1.751e-68	248.0	COG3391@1|root,COG3391@2|Bacteria,1MWMT@1224|Proteobacteria,1S7U7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_3032787_1	290397.Adeh_2952	1.311e-74	274.0	COG1607@1|root,COG1607@2|Bacteria,1Q9RF@1224|Proteobacteria,42Q5P@68525|delta/epsilon subdivisions,2WJY5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_3059516_0	589865.DaAHT2_0105	1.151e-139	453.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria,2MHQS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_3059516_1	1167006.UWK_00092	8.534e-129	422.0	COG0683@1|root,COG0683@2|Bacteria,1MXR4@1224|Proteobacteria,42MXX@68525|delta/epsilon subdivisions,2WKJM@28221|Deltaproteobacteria,2MHQS@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_3059516_5	485915.Dret_1138	8.607e-43	161.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria,2MBI7@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Amino acid-binding ACT	-	-	-	-	-	-	-	-	-	-	-	-	ACT
REGS1_k127_3059516_3	483219.LILAB_15505	1.032e-49	192.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,431W2@68525|delta/epsilon subdivisions,2WWR4@28221|Deltaproteobacteria,2YV9K@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
REGS1_k127_3059516_6	290397.Adeh_2652	3.637e-28	117.0	COG0607@1|root,COG0607@2|Bacteria,1PEZQ@1224|Proteobacteria,42X5U@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_3059516_2	1172188.KB911821_gene1609	1.225e-68	244.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4FGV8@85021|Intrasporangiaceae	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
REGS1_k127_3059516_4	227377.CBU_1788	1.009e-48	180.0	COG0449@1|root,COG0449@2|Bacteria,1RGWX@1224|Proteobacteria,1SPE9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
REGS1_k127_3073482_4	404589.Anae109_3743	1.842e-123	401.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2YVVU@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_3073482_6	290397.Adeh_3613	1.501e-64	225.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42U6G@68525|delta/epsilon subdivisions,2WQDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195	PgpA
REGS1_k127_3073482_1	404589.Anae109_3745	2.884e-189	608.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2YUQX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
REGS1_k127_3073482_0	290397.Adeh_3616	0.0	1285.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	BSP,Bac_surface_Ag,PD40
REGS1_k127_3073482_2	404589.Anae109_3750	2.865e-176	558.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YWK7@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
REGS1_k127_3073482_3	411464.DESPIG_02162	1.535e-161	523.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2M904@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
REGS1_k127_3085598_2	290397.Adeh_0920	1.166e-18	102.0	2EPJ1@1|root,33H5P@2|Bacteria,1PP7Z@1224|Proteobacteria,432VT@68525|delta/epsilon subdivisions,2WYJ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3085598_0	290397.Adeh_1374	5.193e-160	535.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
REGS1_k127_3085598_1	63737.Npun_F4393	5.499e-20	98.0	2DPNX@1|root,332TS@2|Bacteria,1G8ZZ@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3089978_0	290397.Adeh_0639	4.761e-219	688.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_3089978_1	290397.Adeh_0640	8.018e-28	115.0	COG1396@1|root,COG1396@2|Bacteria,1QYFR@1224|Proteobacteria,43CBW@68525|delta/epsilon subdivisions,2X7MR@28221|Deltaproteobacteria,2Z2CU@29|Myxococcales	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
REGS1_k127_3089978_2	404589.Anae109_0686	3.175e-14	86.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
REGS1_k127_3097564_0	483219.LILAB_04875	1.042e-220	704.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YUB2@29|Myxococcales	28221|Deltaproteobacteria	KL	Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc
REGS1_k127_3097564_5	1114964.L485_16510	1.979e-23	105.0	COG2944@1|root,COG2944@2|Bacteria,1QV9M@1224|Proteobacteria,2USEH@28211|Alphaproteobacteria,2KA8X@204457|Sphingomonadales	204457|Sphingomonadales	K	Antitoxin component of bacterial toxin-antitoxin system, MqsA	-	-	-	-	-	-	-	-	-	-	-	-	MqsA_antitoxin
REGS1_k127_3097564_4	1499967.BAYZ01000104_gene3685	1.765e-23	105.0	2D16E@1|root,3327Z@2|Bacteria	2|Bacteria	S	Motility quorum-sensing regulator, toxin of MqsA	-	-	-	ko:K13651	-	-	-	-	ko00000,ko02048	-	-	-	MqsR_toxin
REGS1_k127_3097564_6	596151.DesfrDRAFT_0989	6.627e-05	54.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions,2WNNI@28221|Deltaproteobacteria,2MC6M@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
REGS1_k127_3097564_3	404589.Anae109_1684	3.157e-32	130.0	COG0782@1|root,COG0782@2|Bacteria,1MZNY@1224|Proteobacteria	1224|Proteobacteria	K	nucleoside diphosphate kinase	rnk	-	-	ko:K06140	-	-	-	-	ko00000,ko03000	-	-	-	GreA_GreB,Rnk_N
REGS1_k127_3097564_1	404589.Anae109_4015	1.107e-119	394.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
REGS1_k127_3097564_2	404589.Anae109_4016	3.686e-86	294.0	COG2378@1|root,COG2378@2|Bacteria	2|Bacteria	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	WYL
REGS1_k127_3126231_1	404589.Anae109_0388	8.106e-64	225.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2X2EG@28221|Deltaproteobacteria,2Z20T@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Redoxin
REGS1_k127_3126231_0	290397.Adeh_4039	9.054e-125	408.0	COG3804@1|root,COG3804@2|Bacteria,1N3H7@1224|Proteobacteria,433QN@68525|delta/epsilon subdivisions,2WYE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Dihydrodipicolinate reductase, N-terminus	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
REGS1_k127_3126231_2	404589.Anae109_0390	2.041e-60	227.0	COG2030@1|root,COG2030@2|Bacteria,1RJ2Z@1224|Proteobacteria,4313S@68525|delta/epsilon subdivisions,2WX4Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
REGS1_k127_3126231_3	404589.Anae109_0391	1.829e-44	172.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
REGS1_k127_3151028_5	502025.Hoch_1803	2.572e-19	96.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2Z1R9@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
REGS1_k127_3151028_1	404589.Anae109_0319	2.215e-148	477.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42QF3@68525|delta/epsilon subdivisions,2WKPQ@28221|Deltaproteobacteria,2YYXT@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_3151028_4	1121920.AUAU01000009_gene1874	3.494e-30	130.0	COG0767@1|root,COG0767@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
REGS1_k127_3151028_6	59374.Fisuc_1149	3.977e-11	76.0	COG1127@1|root,COG1127@2|Bacteria	2|Bacteria	Q	ATPase activity	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
REGS1_k127_3151028_8	1191523.MROS_0525	5.242e-07	61.0	COG1463@1|root,COG1463@2|Bacteria	2|Bacteria	Q	ABC-type transport system involved in resistance to organic solvents, periplasmic component	ttg2C	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
REGS1_k127_3151028_7	1538295.JY96_11440	2.631e-10	63.0	COG1145@1|root,COG1145@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	napF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896	-	ko:K02572	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7,Fer4_9
REGS1_k127_3151028_2	404589.Anae109_2874	9.276e-142	481.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
REGS1_k127_3151028_0	748247.AZKH_0382	3.304e-170	545.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	LuxE
REGS1_k127_3151028_3	338963.Pcar_1451	7.152e-73	255.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,42MGS@68525|delta/epsilon subdivisions,2WJ1K@28221|Deltaproteobacteria,43U89@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	amino acid-binding ACT domain protein	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
REGS1_k127_3175146_4	404589.Anae109_3937	7.464e-19	88.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2YVFT@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
REGS1_k127_3175146_1	404589.Anae109_3938	1.514e-76	267.0	COG2003@1|root,COG2003@2|Bacteria	2|Bacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	HHH,RadC
REGS1_k127_3175146_0	522306.CAP2UW1_3705	6.037e-192	634.0	COG0366@1|root,COG0366@2|Bacteria,1MU90@1224|Proteobacteria,2VHF6@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Alpha amylase, catalytic domain	malS	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
REGS1_k127_3175146_3	929712.KI912613_gene3751	2.76e-30	127.0	COG3631@1|root,COG3631@2|Bacteria,2GY2B@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
REGS1_k127_3175146_2	1254432.SCE1572_05640	1.021e-46	191.0	COG0457@1|root,COG0457@2|Bacteria,1PD9R@1224|Proteobacteria,438X9@68525|delta/epsilon subdivisions,2X9TA@28221|Deltaproteobacteria,2YY3E@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3187042_10	1127134.NOCYR_3208	1.696e-20	97.0	COG1309@1|root,COG1309@2|Bacteria,2IMN5@201174|Actinobacteria,4FZ7T@85025|Nocardiaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
REGS1_k127_3187042_6	404589.Anae109_0149	1.007e-55	219.0	COG0745@1|root,COG0745@2|Bacteria	404589.Anae109_0149|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3187042_1	404589.Anae109_0150	1.343e-155	499.0	COG2404@1|root,COG2404@2|Bacteria,1QW0R@1224|Proteobacteria,43BQN@68525|delta/epsilon subdivisions,2X71Q@28221|Deltaproteobacteria,2YUZT@29|Myxococcales	28221|Deltaproteobacteria	S	COG0618 Exopolyphosphatase-related proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3187042_12	1117315.AHCA01000014_gene3913	3.555e-08	61.0	2CJNH@1|root,32U6W@2|Bacteria,1N1FA@1224|Proteobacteria,1S98N@1236|Gammaproteobacteria,2Q4R2@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	S	Bor protein	-	-	-	-	-	-	-	-	-	-	-	-	Lambda_Bor
REGS1_k127_3187042_3	290397.Adeh_3438	1.448e-93	317.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42NQP@68525|delta/epsilon subdivisions,2WIQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	BQ	PFAM Histone deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
REGS1_k127_3187042_9	1239962.C943_04327	6.352e-24	106.0	COG4704@1|root,COG4704@2|Bacteria,4NUS8@976|Bacteroidetes,47S7U@768503|Cytophagia	976|Bacteroidetes	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
REGS1_k127_3187042_0	290397.Adeh_0146	5.709e-174	553.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,2YUU0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
REGS1_k127_3187042_2	290397.Adeh_0147	3.351e-129	459.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2YV1E@29|Myxococcales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
REGS1_k127_3187042_7	404589.Anae109_0153	1.078e-44	179.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
REGS1_k127_3187042_5	404589.Anae109_0154	2.19e-56	209.0	COG3444@1|root,COG3444@2|Bacteria,1R4ES@1224|Proteobacteria,42VCG@68525|delta/epsilon subdivisions,2WRN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM PTS system sorbose subfamily IIB component	-	-	2.7.1.191	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	PTSIIB_sorb
REGS1_k127_3187042_8	404589.Anae109_0155	4.145e-35	141.0	COG3715@1|root,COG3715@2|Bacteria,1RHFJ@1224|Proteobacteria,42SZF@68525|delta/epsilon subdivisions,2WPSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PTS system	-	-	-	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.6.1	-	-	EII-Sor
REGS1_k127_3225009_7	391625.PPSIR1_41879	7.278e-66	251.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42M5H@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	FOG TPR repeat SEL1 subfamily	hcpD	GO:0003674,GO:0003824,GO:0008800,GO:0016787,GO:0016810,GO:0016812	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_8
REGS1_k127_3225009_10	595460.RRSWK_04826	9.157e-25	109.0	2EBTY@1|root,335TG@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
REGS1_k127_3225009_8	290397.Adeh_0436	2.632e-46	170.0	COG0607@1|root,COG0607@2|Bacteria,1PE42@1224|Proteobacteria,42V5T@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_3225009_5	497964.CfE428DRAFT_0680	2.187e-93	318.0	2DB8X@1|root,2Z7T1@2|Bacteria	2|Bacteria	S	PFAM Suppressor of fused	btrU	-	-	-	-	-	-	-	-	-	-	-	SUFU
REGS1_k127_3225009_12	1286171.EAL2_808p01160	6.038e-05	51.0	2BTJQ@1|root,32NSA@2|Bacteria,1W04H@1239|Firmicutes,253S3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3225009_9	926550.CLDAP_06870	7.241e-35	143.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
REGS1_k127_3225009_1	1163617.SCD_n00481	6.484e-168	551.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2VHE1@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
REGS1_k127_3225009_6	404589.Anae109_3649	1.843e-72	257.0	2CJTZ@1|root,32SAS@2|Bacteria,1N3WB@1224|Proteobacteria,42XK5@68525|delta/epsilon subdivisions,2WSKQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3553
REGS1_k127_3225009_2	269799.Gmet_2566	3.413e-163	526.0	28HIY@1|root,2Z7U8@2|Bacteria,1MY3K@1224|Proteobacteria,42QIR@68525|delta/epsilon subdivisions,2WME0@28221|Deltaproteobacteria,43UIM@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3225009_11	1348657.M622_16310	8.996e-23	114.0	2AQ4B@1|root,31F9K@2|Bacteria,1N38C@1224|Proteobacteria,2VRH0@28216|Betaproteobacteria,2KYV0@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3225009_3	290397.Adeh_2931	2.903e-157	500.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,42M13@68525|delta/epsilon subdivisions,2WPM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
REGS1_k127_3225009_4	290397.Adeh_2932	5.387e-150	479.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WK9D@28221|Deltaproteobacteria,2YXAV@29|Myxococcales	28221|Deltaproteobacteria	C	Fumarate reductase, iron-sulfur protein	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2395	Fer2_3,Fer4_7,Fer4_8
REGS1_k127_3225009_0	290397.Adeh_2933	3.166e-296	911.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,2Z30R@29|Myxococcales	28221|Deltaproteobacteria	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_3234687_0	290397.Adeh_3183	1.326e-175	575.0	2DPRW@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,3334N@2|Bacteria,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
REGS1_k127_32352_1	644966.Tmar_0951	2.569e-99	338.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WCS5@538999|Clostridiales incertae sedis	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_32352_2	1303518.CCALI_00238	1.162e-43	168.0	COG1028@1|root,COG1028@2|Bacteria	1303518.CCALI_00238|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	-
REGS1_k127_32352_6	158500.BV97_04431	3.199e-08	62.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2UTSJ@28211|Alphaproteobacteria,2KAXG@204457|Sphingomonadales	204457|Sphingomonadales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_32352_4	582515.KR51_00008450	1.32e-29	132.0	COG2091@1|root,COG2091@2|Bacteria,1G5GA@1117|Cyanobacteria	1117|Cyanobacteria	H	Belongs to the P-Pant transferase superfamily	hetI	GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
REGS1_k127_32352_3	290397.Adeh_0689	9.081e-40	152.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,2YVT9@29|Myxococcales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
REGS1_k127_32352_0	1379698.RBG1_1C00001G0016	9.891e-125	421.0	COG2204@1|root,COG2204@2|Bacteria,2NNPN@2323|unclassified Bacteria	2|Bacteria	T	COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_32352_5	87626.PTD2_14982	2.293e-15	81.0	2F2W9@1|root,33VS1@2|Bacteria,1NW3V@1224|Proteobacteria,1SNYC@1236|Gammaproteobacteria	87626.PTD2_14982|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3245316_3	404589.Anae109_3756	2.208e-92	323.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8,YfiO
REGS1_k127_3245316_0	215803.DB30_6044	4.219e-282	914.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria,2YUCZ@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
REGS1_k127_3245316_2	215803.DB30_6043	2.667e-101	361.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,1Q2EC@1224|Proteobacteria,43804@68525|delta/epsilon subdivisions,2X3A2@28221|Deltaproteobacteria,2YV2B@29|Myxococcales	28221|Deltaproteobacteria	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
REGS1_k127_3245316_5	246197.MXAN_1924	9.151e-76	262.0	29RMJ@1|root,30CQT@2|Bacteria,1QTPA@1224|Proteobacteria,4380Z@68525|delta/epsilon subdivisions,2X3B0@28221|Deltaproteobacteria,2YV6U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3245316_1	404589.Anae109_3758	5.932e-121	389.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
REGS1_k127_3245316_4	290397.Adeh_3634	4.691e-89	295.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2YV9Q@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
REGS1_k127_3245316_6	290397.Adeh_3635	2.109e-13	69.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2YYNH@29|Myxococcales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
REGS1_k127_3267259_0	290397.Adeh_2432	0.0	1046.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2WIWF@28221|Deltaproteobacteria,2YUMB@29|Myxococcales	28221|Deltaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
REGS1_k127_3267259_1	290397.Adeh_2433	1.193e-114	375.0	COG2013@1|root,COG2013@2|Bacteria,1NBBE@1224|Proteobacteria,42N2E@68525|delta/epsilon subdivisions,2WJFV@28221|Deltaproteobacteria,2YVMD@29|Myxococcales	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
REGS1_k127_3267259_2	290397.Adeh_2434	1.081e-58	214.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2X5HK@28221|Deltaproteobacteria,2Z35S@29|Myxococcales	28221|Deltaproteobacteria	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
REGS1_k127_330499_4	290397.Adeh_3638	1.11e-75	258.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
REGS1_k127_330499_10	379066.GAU_1412	5.323e-10	73.0	COG0457@1|root,COG0457@2|Bacteria,1ZSPN@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,TPR_16,TPR_2
REGS1_k127_330499_7	324602.Caur_0486	3.775e-50	196.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2G67H@200795|Chloroflexi,374SX@32061|Chloroflexia	32061|Chloroflexia	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
REGS1_k127_330499_5	1304885.AUEY01000004_gene1010	6.293e-74	259.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K03776	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	PAS_3
REGS1_k127_330499_8	243231.GSU0582	6.982e-45	170.0	COG0840@1|root,COG0840@2|Bacteria,1NJXF@1224|Proteobacteria,42RAH@68525|delta/epsilon subdivisions,2WKVU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Chemotaxis sensory transducer	mcp40H-2	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
REGS1_k127_330499_2	243231.GSU1538	6.44e-138	456.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N38@68525|delta/epsilon subdivisions,2WK56@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Cytochrom_C
REGS1_k127_330499_0	290397.Adeh_3640	2.157e-241	765.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2Z2X2@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_330499_3	290397.Adeh_3641	1.125e-79	278.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
REGS1_k127_330499_1	404589.Anae109_3768	6.481e-151	495.0	COG0457@1|root,COG0457@2|Bacteria,1R7XY@1224|Proteobacteria,42NFC@68525|delta/epsilon subdivisions,2WMA4@28221|Deltaproteobacteria,2Z18K@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
REGS1_k127_330499_9	290397.Adeh_3643	5.086e-37	158.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,2YUZJ@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
REGS1_k127_3324052_8	290397.Adeh_4081	2.303e-36	146.0	COG0484@1|root,COG0484@2|Bacteria,1N40E@1224|Proteobacteria	1224|Proteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3324052_3	290397.Adeh_3513	1.433e-126	425.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K03776,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
REGS1_k127_3324052_1	1122604.JONR01000049_gene753	3.807e-220	695.0	COG0659@1|root,COG0659@2|Bacteria,1MXA7@1224|Proteobacteria,1RQYD@1236|Gammaproteobacteria,1X46G@135614|Xanthomonadales	135614|Xanthomonadales	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
REGS1_k127_3324052_5	448385.sce9236	1.991e-116	402.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,VWA_2
REGS1_k127_3324052_9	404589.Anae109_2891	2.261e-27	113.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42V9P@68525|delta/epsilon subdivisions,2X5QW@28221|Deltaproteobacteria,2Z1ZE@29|Myxococcales	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
REGS1_k127_3324052_10	404589.Anae109_0891	3.964e-14	88.0	COG1538@1|root,COG1538@2|Bacteria,1Q6D1@1224|Proteobacteria,432WU@68525|delta/epsilon subdivisions,2WXU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_3324052_0	330214.NIDE0726	5.051e-320	1016.0	COG0841@1|root,COG0841@2|Bacteria,3J0ZG@40117|Nitrospirae	40117|Nitrospirae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_3324052_7	1123253.AUBD01000001_gene1664	1.942e-37	154.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,1RN0S@1236|Gammaproteobacteria,1X433@135614|Xanthomonadales	135614|Xanthomonadales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
REGS1_k127_3324052_2	290397.Adeh_2054	1.187e-217	706.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	AsmA family	asmA	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
REGS1_k127_3324052_6	290397.Adeh_3592	7.515e-72	247.0	2DKHM@1|root,309GY@2|Bacteria,1RFJ6@1224|Proteobacteria,43BG3@68525|delta/epsilon subdivisions,2X6UE@28221|Deltaproteobacteria,2Z3CV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3324052_4	404589.Anae109_1615	7.804e-124	402.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,2Z0ES@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
REGS1_k127_3326879_0	404589.Anae109_0385	0.0	1062.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,2YU3T@29|Myxococcales	28221|Deltaproteobacteria	G	pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_3326879_4	404589.Anae109_0627	9.519e-16	82.0	2ANPU@1|root,31DPC@2|Bacteria,1QB0N@1224|Proteobacteria,435DB@68525|delta/epsilon subdivisions,2WZQX@28221|Deltaproteobacteria,2Z2JD@29|Myxococcales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_3326879_1	290397.Adeh_4043	1.943e-134	440.0	COG0768@1|root,COG0768@2|Bacteria,1R7A0@1224|Proteobacteria,42MJC@68525|delta/epsilon subdivisions,2WJZ2@28221|Deltaproteobacteria,2YV14@29|Myxococcales	28221|Deltaproteobacteria	M	Cell division protein FtsI penicillin-binding protein 2	pbp4	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
REGS1_k127_3326879_3	1267535.KB906767_gene4200	2.017e-23	106.0	COG0745@1|root,COG0745@2|Bacteria,3Y81M@57723|Acidobacteria	57723|Acidobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_3326879_2	404589.Anae109_0387	1.862e-117	389.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
REGS1_k127_333274_2	290397.Adeh_1309	8.997e-18	87.0	COG1716@1|root,COG1716@2|Bacteria,1QJBG@1224|Proteobacteria,433TM@68525|delta/epsilon subdivisions,2X3EM@28221|Deltaproteobacteria,2YVQN@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
REGS1_k127_333534_2	290397.Adeh_3829	2.151e-74	253.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,42SPQ@68525|delta/epsilon subdivisions,2WPX1@28221|Deltaproteobacteria,2YWQX@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
REGS1_k127_333534_0	404589.Anae109_3944	4.574e-207	657.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2Z0VZ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_333534_1	290397.Adeh_3834	3.172e-86	299.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	ko:K13582,ko:K21471	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	CHAP,DUF4349,Peptidase_M23,Rib,SLT,Sel1
REGS1_k127_333534_3	404589.Anae109_3948	2.465e-30	120.0	COG1192@1|root,COG1192@2|Bacteria,1RK00@1224|Proteobacteria	1224|Proteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
REGS1_k127_3337204_4	1045858.Bint_1447	1.199e-89	321.0	COG0028@1|root,COG0028@2|Bacteria,2JA2V@203691|Spirochaetes	203691|Spirochaetes	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
REGS1_k127_3337204_1	1159870.KB907784_gene2777	1.17e-192	605.0	COG2089@1|root,COG2089@2|Bacteria,1MWG3@1224|Proteobacteria,2VHMH@28216|Betaproteobacteria	28216|Betaproteobacteria	M	synthase	-	-	2.5.1.56	ko:K01654	ko00520,ko01100,map00520,map01100	-	R01804,R04435	RC00159	ko00000,ko00001,ko01000	-	-	-	Cupin_2,NeuB
REGS1_k127_3337204_7	1408428.JNJP01000015_gene462	9.443e-32	133.0	COG0546@1|root,COG0546@2|Bacteria,1Q5CN@1224|Proteobacteria,4311B@68525|delta/epsilon subdivisions,2WWN6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_3337204_3	886293.Sinac_3928	2.722e-122	404.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_3337204_0	404589.Anae109_4444	1.376e-239	759.0	COG1215@1|root,COG2227@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria,1QTWG@1224|Proteobacteria,43CD4@68525|delta/epsilon subdivisions,2WRY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HM	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_12
REGS1_k127_3337204_2	404589.Anae109_3213	8.704e-150	498.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
REGS1_k127_3337204_5	290397.Adeh_4306	6.695e-70	243.0	COG2802@1|root,COG2802@2|Bacteria	2|Bacteria	S	histone H2A-K13 ubiquitination	lonD	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
REGS1_k127_3337204_6	290397.Adeh_4307	1.676e-32	127.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42P3K@68525|delta/epsilon subdivisions,2WMB8@28221|Deltaproteobacteria,2YWYR@29|Myxococcales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
REGS1_k127_3350025_5	290397.Adeh_0731	6.612e-125	409.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,2YUYM@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
REGS1_k127_3350025_1	404589.Anae109_0774	2.341e-233	729.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2YU66@29|Myxococcales	28221|Deltaproteobacteria	L	AAA C-terminal domain	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
REGS1_k127_3350025_7	290397.Adeh_0729	3.096e-75	258.0	COG1073@1|root,COG1073@2|Bacteria,1PBV5@1224|Proteobacteria,433TK@68525|delta/epsilon subdivisions,2X3EJ@28221|Deltaproteobacteria,2YVQG@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0227)	-	-	-	ko:K07000	-	-	-	-	ko00000	-	-	-	UPF0227
REGS1_k127_3350025_9	1125863.JAFN01000001_gene1323	4.389e-34	139.0	COG2402@1|root,COG2402@2|Bacteria,1NK19@1224|Proteobacteria,432DQ@68525|delta/epsilon subdivisions,2WY2Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_3350025_0	404589.Anae109_3581	2.789e-251	786.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_3350025_2	290397.Adeh_3472	2.67e-230	725.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N5C@68525|delta/epsilon subdivisions,2WM18@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
REGS1_k127_3350025_4	290397.Adeh_3473	5.38e-150	480.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria,2YVAA@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
REGS1_k127_3350025_3	290397.Adeh_3475	3.791e-198	631.0	COG1181@1|root,COG1181@2|Bacteria,1QXU6@1224|Proteobacteria,43C6Q@68525|delta/epsilon subdivisions,2X7NN@28221|Deltaproteobacteria,2Z3H4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3350025_8	290397.Adeh_3476	9.889e-52	192.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
REGS1_k127_3350025_6	404589.Anae109_3588	1.105e-96	321.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria	1224|Proteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG_1	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
REGS1_k127_3364805_1	861299.J421_3442	2.632e-20	98.0	COG3027@1|root,COG3027@2|Bacteria,1ZU4G@142182|Gemmatimonadetes	142182|Gemmatimonadetes	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
REGS1_k127_3364805_3	861299.J421_3443	4.701e-05	55.0	28U49@1|root,2ZGA9@2|Bacteria,1ZU72@142182|Gemmatimonadetes	142182|Gemmatimonadetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3364805_0	1278073.MYSTI_04356	1.116e-152	511.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
REGS1_k127_3414701_0	378806.STAUR_4452	0.0	1025.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,42MYQ@68525|delta/epsilon subdivisions,2WJM2@28221|Deltaproteobacteria,2YTST@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
REGS1_k127_3414701_1	290397.Adeh_1613	3.725e-98	323.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
REGS1_k127_3460888_2	290397.Adeh_3849	5.633e-73	255.0	COG0300@1|root,COG0300@2|Bacteria,1MWNZ@1224|Proteobacteria,43AM2@68525|delta/epsilon subdivisions,2X617@28221|Deltaproteobacteria,2YZY5@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
REGS1_k127_3460888_3	290397.Adeh_3852	1.466e-57	207.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_3460888_0	404589.Anae109_3978	1.354e-93	310.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2YWV6@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
REGS1_k127_3467993_2	1144275.COCOR_03984	3.016e-13	71.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
REGS1_k127_3467993_1	290397.Adeh_2396	6.919e-119	409.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42URW@68525|delta/epsilon subdivisions,2WQAX@28221|Deltaproteobacteria,2Z1XF@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
REGS1_k127_3467993_0	1286631.X805_19670	4.342e-165	536.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KIU5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
REGS1_k127_3484400_5	290397.Adeh_4032	1.685e-07	62.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
REGS1_k127_3484400_1	404589.Anae109_0397	5.404e-118	385.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42MFD@68525|delta/epsilon subdivisions,2WJCZ@28221|Deltaproteobacteria,2YXV3@29|Myxococcales	28221|Deltaproteobacteria	K	PFAM Silent information regulator protein Sir2	-	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
REGS1_k127_3484400_4	290397.Adeh_0096	4.923e-12	78.0	298JI@1|root,2ZVQE@2|Bacteria,1P8JU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3484400_0	290397.Adeh_4026	3.736e-156	501.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,2Z2YT@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
REGS1_k127_3484400_3	290397.Adeh_4022	4.603e-29	120.0	COG0607@1|root,COG0607@2|Bacteria,1PE42@1224|Proteobacteria,42V5T@68525|delta/epsilon subdivisions,2WZAQ@28221|Deltaproteobacteria,2Z1QM@29|Myxococcales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_3484400_2	404589.Anae109_0405	1.395e-29	124.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	amino acid peptide transporter	dtpA	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
REGS1_k127_3492774_5	1297570.MESS4_210055	1.694e-63	242.0	COG0642@1|root,COG2205@2|Bacteria,1NFY3@1224|Proteobacteria,2TSQR@28211|Alphaproteobacteria,43MKT@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	MA20_06300	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_3492774_4	246197.MXAN_4164	3.02e-80	273.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42UVV@68525|delta/epsilon subdivisions,2WUTB@28221|Deltaproteobacteria,2YUY6@29|Myxococcales	28221|Deltaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_3492774_9	215803.DB30_2657	3.615e-44	181.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_3,Kelch_4,Kelch_6,REJ
REGS1_k127_3492774_8	404589.Anae109_3642	1.184e-50	200.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WNEC@28221|Deltaproteobacteria,2YUZQ@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
REGS1_k127_3492774_0	290397.Adeh_1023	5.56e-199	631.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,42M0Z@68525|delta/epsilon subdivisions,2WK36@28221|Deltaproteobacteria,2Z0TJ@29|Myxococcales	28221|Deltaproteobacteria	P	arsenical-resistance protein	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
REGS1_k127_3492774_7	404589.Anae109_3644	4.192e-51	184.0	COG0640@1|root,COG0640@2|Bacteria,1N7I7@1224|Proteobacteria,42VTU@68525|delta/epsilon subdivisions,2WRGJ@28221|Deltaproteobacteria,2YVHK@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
REGS1_k127_3492774_10	404589.Anae109_3645	9.117e-36	141.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_3492774_3	290397.Adeh_1026	8.359e-90	301.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
REGS1_k127_3492774_2	290397.Adeh_1027	3.075e-107	364.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
REGS1_k127_3501791_0	1121422.AUMW01000006_gene780	8.219e-132	444.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia	186801|Clostridia	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_3517185_1	404589.Anae109_3158	2.988e-95	314.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2YUAS@29|Myxococcales	28221|Deltaproteobacteria	P	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_3517185_2	1217718.ALOU01000019_gene2751	4.716e-84	282.0	COG0431@1|root,COG0431@2|Bacteria,1RAFI@1224|Proteobacteria,2VKQS@28216|Betaproteobacteria,1K02Y@119060|Burkholderiaceae	28216|Betaproteobacteria	S	NADPH-dependent FMN reductase	azr	-	-	ko:K19784	-	-	-	-	ko00000	-	-	-	FMN_red
REGS1_k127_3517185_3	404589.Anae109_3132	6.554e-26	114.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
REGS1_k127_3517185_0	386456.JQKN01000010_gene655	3.664e-149	489.0	COG5276@1|root,arCOG02565@2157|Archaea	2157|Archaea	O	LVIVD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
REGS1_k127_3517185_4	1120949.KB903350_gene8332	3.669e-08	55.0	COG0667@1|root,COG0667@2|Bacteria,2GJBG@201174|Actinobacteria,4D8HU@85008|Micromonosporales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_3540021_0	290397.Adeh_3319	2.315e-101	332.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
REGS1_k127_3540021_2	404589.Anae109_3372	2.004e-38	150.0	COG0457@1|root,COG0457@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
REGS1_k127_3548215_2	404589.Anae109_1641	1.619e-45	165.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,42PIX@68525|delta/epsilon subdivisions,2WJRF@28221|Deltaproteobacteria,2Z360@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
REGS1_k127_3548215_0	404589.Anae109_1640	9.23e-135	440.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,42ND8@68525|delta/epsilon subdivisions,2WN93@28221|Deltaproteobacteria,2YWH9@29|Myxococcales	28221|Deltaproteobacteria	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
REGS1_k127_3548215_1	404589.Anae109_1639	4.94e-120	406.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria	1224|Proteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008272,GO:0008509,GO:0015075,GO:0015103,GO:0015116,GO:0015318,GO:0015399,GO:0015405,GO:0015419,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0072348,GO:0097159,GO:0097367,GO:0098656,GO:0098660,GO:0098661,GO:0099133,GO:1901265,GO:1901363,GO:1901682,GO:1902358	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	iE2348C_1286.E2348C_2607,iSSON_1240.SSON_2511	ABC_tran,TOBE_3
REGS1_k127_3555639_1	290397.Adeh_0602	9.787e-05	45.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5EQ@28221|Deltaproteobacteria,2Z35B@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_3555639_0	290397.Adeh_3513	6.897e-181	586.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria	1224|Proteobacteria	NT	Methyl-accepting chemotaxis protein	-	-	-	ko:K03406,ko:K03776,ko:K05874	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
REGS1_k127_3555754_6	404589.Anae109_1180	1.35e-37	149.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2Z0IS@29|Myxococcales	28221|Deltaproteobacteria	P	CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
REGS1_k127_3555754_2	290397.Adeh_1824	6.272e-97	328.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,42SXI@68525|delta/epsilon subdivisions,2WPTR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
REGS1_k127_3555754_0	404589.Anae109_1997	3.137e-116	393.0	COG1179@1|root,COG1179@2|Bacteria	2|Bacteria	H	involved in molybdopterin and THIamine biosynthesis family 1	ygdL	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029,ko:K22132	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiF
REGS1_k127_3555754_9	443143.GM18_2750	1.849e-16	93.0	COG0671@1|root,COG0671@2|Bacteria,1NDCB@1224|Proteobacteria,42W6H@68525|delta/epsilon subdivisions,2WREU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
REGS1_k127_3555754_3	1121920.AUAU01000018_gene1786	4.476e-94	319.0	COG0508@1|root,COG0508@2|Bacteria	2|Bacteria	C	S-acyltransferase activity	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh
REGS1_k127_3555754_5	1254432.SCE1572_24340	9.942e-43	178.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_3555754_4	483219.LILAB_31335	9.532e-89	308.0	COG1721@1|root,COG1721@2|Bacteria,1MXDI@1224|Proteobacteria	1224|Proteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_3555754_1	292459.STH463	1.563e-110	369.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_3555754_8	378806.STAUR_0615	6.633e-18	92.0	2APHR@1|root,31EKS@2|Bacteria,1QBX0@1224|Proteobacteria,435IF@68525|delta/epsilon subdivisions,2WZW3@28221|Deltaproteobacteria,2Z2VA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3555754_7	378806.STAUR_3701	5.336e-23	112.0	2E0NP@1|root,32W7Q@2|Bacteria,1Q906@1224|Proteobacteria,439EQ@68525|delta/epsilon subdivisions,2X4PW@28221|Deltaproteobacteria,2YZDD@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4350
REGS1_k127_3555754_10	1242864.D187_007149	1.14e-07	60.0	2DTE6@1|root,33JYQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3564153_9	335543.Sfum_0325	1.308e-15	76.0	COG0655@1|root,COG0655@2|Bacteria,1RAK6@1224|Proteobacteria,42QS5@68525|delta/epsilon subdivisions,2WN2M@28221|Deltaproteobacteria,2MQXT@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_3564153_6	290397.Adeh_0346	5.831e-34	143.0	2BUNJ@1|root,32PZE@2|Bacteria,1NFZZ@1224|Proteobacteria,42XI7@68525|delta/epsilon subdivisions,2WTGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3564153_5	358681.BBR47_30240	6.758e-42	172.0	28HBI@1|root,2Z7NH@2|Bacteria,1VDJT@1239|Firmicutes,4IRD8@91061|Bacilli,270RV@186822|Paenibacillaceae	91061|Bacilli	S	Protein of unknown function (DUF4241)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4241
REGS1_k127_3564153_8	180281.CPCC7001_907	1.607e-21	100.0	2B8JF@1|root,321UP@2|Bacteria,1GMSQ@1117|Cyanobacteria,22TUT@167375|Cyanobium	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3564153_4	180281.CPCC7001_1150	2.498e-42	166.0	COG2337@1|root,COG2337@2|Bacteria,1G6KE@1117|Cyanobacteria,22T6U@167375|Cyanobium	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
REGS1_k127_3564153_2	290397.Adeh_1040	6.582e-78	271.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,42RN4@68525|delta/epsilon subdivisions,2WP37@28221|Deltaproteobacteria,2YVD3@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
REGS1_k127_3564153_3	404589.Anae109_1090	6.819e-47	176.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2X3DV@28221|Deltaproteobacteria,2YVMF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
REGS1_k127_3564153_7	404589.Anae109_1091	3.114e-31	124.0	COG1145@1|root,COG1145@2|Bacteria,1QUJB@1224|Proteobacteria,42TSI@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Ferredoxin	fdxA	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
REGS1_k127_3564153_1	404589.Anae109_1093	2.76e-85	287.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,42T4F@68525|delta/epsilon subdivisions,2WP6B@28221|Deltaproteobacteria,2YVEY@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
REGS1_k127_3564153_0	290397.Adeh_1044	9.027e-144	458.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2YU10@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
REGS1_k127_3564471_2	290397.Adeh_0652	3.098e-160	508.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42MM0@68525|delta/epsilon subdivisions,2WKXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
REGS1_k127_3564471_0	404589.Anae109_0698	0.0	1253.0	COG2911@1|root,COG2911@2|Bacteria,1PQTA@1224|Proteobacteria,42PYT@68525|delta/epsilon subdivisions,2WIZ6@28221|Deltaproteobacteria,2YVF0@29|Myxococcales	28221|Deltaproteobacteria	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
REGS1_k127_3564471_1	290397.Adeh_0654	1.581e-251	854.0	COG4775@1|root,COG4775@2|Bacteria,1RJPJ@1224|Proteobacteria,42TA2@68525|delta/epsilon subdivisions,2WP1H@28221|Deltaproteobacteria,2YZDW@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
REGS1_k127_3571156_1	1123020.AUIE01000001_gene2197	1.531e-56	199.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,1RMFE@1236|Gammaproteobacteria,1YD2E@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	I	Serine aminopeptidase, S33	cpo	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
REGS1_k127_3571156_0	697282.Mettu_0012	6.158e-67	232.0	COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,1SBIG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_357406_2	1232410.KI421428_gene1098	2.03e-84	288.0	COG1073@1|root,COG1073@2|Bacteria,1RBV1@1224|Proteobacteria,42M9M@68525|delta/epsilon subdivisions,2WM64@28221|Deltaproteobacteria,43UQV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
REGS1_k127_357406_0	1144275.COCOR_00508	2.5e-129	419.0	COG4676@1|root,COG4676@2|Bacteria,1R801@1224|Proteobacteria,42YYR@68525|delta/epsilon subdivisions,2WUBQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2135)	-	-	-	ko:K09934	-	-	-	-	ko00000	-	-	-	DUF2135
REGS1_k127_357406_4	1144275.COCOR_00509	1.408e-52	205.0	COG3234@1|root,COG3234@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1175)	-	-	-	ko:K09934	-	-	-	-	ko00000	-	-	-	DUF1175
REGS1_k127_357406_3	246197.MXAN_0585	4.061e-72	249.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WU7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Thiol-ester_cl
REGS1_k127_3574612_0	404589.Anae109_0731	4.752e-118	403.0	COG3031@1|root,COG3031@2|Bacteria,1PUWN@1224|Proteobacteria,42T73@68525|delta/epsilon subdivisions,2WR4E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSC
REGS1_k127_3574612_1	404589.Anae109_0816	4.791e-93	317.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
REGS1_k127_357976_7	395019.Bmul_4897	5.157e-11	68.0	COG0500@1|root,COG0500@2|Bacteria,1QTX8@1224|Proteobacteria,2VQJT@28216|Betaproteobacteria,1KA92@119060|Burkholderiaceae	28216|Betaproteobacteria	H	PFAM Methyltransferase type 11	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_25
REGS1_k127_357976_5	404589.Anae109_3112	1.067e-29	128.0	2BW7N@1|root,32Z97@2|Bacteria,1P2ZF@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_357976_8	446462.Amir_4941	0.0001472	51.0	290SZ@1|root,2ZNF2@2|Bacteria,2GWHP@201174|Actinobacteria,4ECK3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_357976_6	290397.Adeh_1178	1.102e-11	79.0	COG3197@1|root,COG3197@2|Bacteria,1Q3MJ@1224|Proteobacteria,42XI0@68525|delta/epsilon subdivisions,2WT8I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM cytochrome oxidase maturation protein, cbb3-type	-	-	-	-	-	-	-	-	-	-	-	-	FixS
REGS1_k127_357976_0	290397.Adeh_1177	3.499e-307	961.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WMJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.4	ko:K01533	-	-	R00086	RC00002	ko00000,ko01000	3.A.3.5	-	-	ATPase-cat_bd,E1-E2_ATPase,HMA,Hydrolase
REGS1_k127_357976_2	404589.Anae109_1224	1.049e-60	218.0	COG2836@1|root,COG2836@2|Bacteria,1RIGJ@1224|Proteobacteria,42Q44@68525|delta/epsilon subdivisions,2WRKT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome C biogenesis protein transmembrane region	-	-	-	ko:K09792	-	-	-	-	ko00000	-	-	-	DsbD_2
REGS1_k127_357976_4	398767.Glov_3546	6.424e-54	217.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_357976_1	1242864.D187_000269	3.546e-79	285.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
REGS1_k127_357976_3	404589.Anae109_3864	5.134e-59	207.0	COG1028@1|root,COG1028@2|Bacteria,1MWB6@1224|Proteobacteria,42S4A@68525|delta/epsilon subdivisions,2WNE7@28221|Deltaproteobacteria,2Z30E@29|Myxococcales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
REGS1_k127_3589108_9	290397.Adeh_1086	5.422e-10	59.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,42P40@68525|delta/epsilon subdivisions,2WK7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
REGS1_k127_3589108_7	290397.Adeh_1085	9.684e-57	199.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
REGS1_k127_3589108_6	290397.Adeh_1085	5.045e-57	215.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
REGS1_k127_3589108_5	290397.Adeh_1084	4.058e-65	242.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2YVDF@29|Myxococcales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
REGS1_k127_3589108_3	290397.Adeh_1083	5.224e-150	482.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
REGS1_k127_3589108_8	290397.Adeh_1082	1.349e-35	143.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,2YVZ7@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
REGS1_k127_3589108_0	404589.Anae109_1120	0.0	1045.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2YUN3@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
REGS1_k127_3589108_4	404589.Anae109_1119	2.116e-100	368.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2YURX@29|Myxococcales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
REGS1_k127_3589108_1	290397.Adeh_1079	2.058e-240	758.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2YUSA@29|Myxococcales	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
REGS1_k127_3589108_2	290397.Adeh_1078	8.159e-238	739.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,2YUAA@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
REGS1_k127_3599808_4	243231.GSU2893	1.05e-79	279.0	COG0318@1|root,COG0318@2|Bacteria,1QXPD@1224|Proteobacteria,43C59@68525|delta/epsilon subdivisions,2WRV5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
REGS1_k127_3599808_6	1123267.JONN01000002_gene178	2.129e-25	115.0	COG2020@1|root,COG2020@2|Bacteria,1N936@1224|Proteobacteria	1224|Proteobacteria	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	ICMT,PEMT
REGS1_k127_3599808_0	635013.TherJR_2855	1.708e-187	594.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,2612Q@186807|Peptococcaceae	186801|Clostridia	C	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_3599808_3	882083.SacmaDRAFT_2109	4.412e-95	349.0	COG2220@1|root,COG2220@2|Bacteria,2GNXJ@201174|Actinobacteria,4DYA7@85010|Pseudonocardiales	201174|Actinobacteria	S	Zn-dependent hydrolase of beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
REGS1_k127_3599808_1	373994.Riv7116_6681	6.149e-141	489.0	COG1232@1|root,COG1232@2|Bacteria,1G05M@1117|Cyanobacteria,1HMK8@1161|Nostocales	1117|Cyanobacteria	H	PFAM Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
REGS1_k127_3599808_8	393595.ABO_2362	2.648e-15	91.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1XHTC@135619|Oceanospirillales	135619|Oceanospirillales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
REGS1_k127_3599808_7	1122611.KB903974_gene3136	1.231e-21	111.0	COG1928@1|root,COG1928@2|Bacteria,2I2H1@201174|Actinobacteria,4EFF9@85012|Streptosporangiales	201174|Actinobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	pmt	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_4TMC
REGS1_k127_3599808_10	443144.GM21_0397	9.123e-07	60.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome C family protein	mtrA	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
REGS1_k127_3599808_2	1266925.JHVX01000005_gene1969	3.187e-126	413.0	COG1215@1|root,COG1215@2|Bacteria,1QTWU@1224|Proteobacteria,2WEWI@28216|Betaproteobacteria,374PQ@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
REGS1_k127_3599808_5	1280954.HPO_01385	7.46e-71	251.0	COG0500@1|root,COG0500@2|Bacteria,1RIQB@1224|Proteobacteria,2U356@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
REGS1_k127_3605810_2	575589.HMPREF0018_00386	5.413e-70	243.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,3NM2Z@468|Moraxellaceae	1236|Gammaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
REGS1_k127_3605810_1	290397.Adeh_2665	2.294e-106	353.0	COG0484@1|root,COG0484@2|Bacteria,1QABU@1224|Proteobacteria,434YT@68525|delta/epsilon subdivisions,2WZ9Q@28221|Deltaproteobacteria,2Z1NF@29|Myxococcales	28221|Deltaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3605810_4	290397.Adeh_2664	6.107e-28	132.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3605810_0	404589.Anae109_1215	1.447e-122	401.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_3605810_5	290397.Adeh_3987	7.736e-08	54.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
REGS1_k127_3619200_3	404589.Anae109_1139	5.001e-72	244.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2YUJG@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
REGS1_k127_3619200_1	404589.Anae109_1138	4.242e-81	274.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
REGS1_k127_3619200_4	903818.KI912268_gene625	1.656e-66	237.0	COG0583@1|root,COG0583@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	cysL_1	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
REGS1_k127_3619200_5	667014.Thein_0108	5.481e-53	209.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
REGS1_k127_3619200_0	290397.Adeh_1098	1.006e-119	399.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2YV01@29|Myxococcales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
REGS1_k127_3619200_2	290397.Adeh_1097	6.185e-77	262.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
REGS1_k127_3620646_1	404589.Anae109_0769	3.324e-31	127.0	COG0484@1|root,COG2199@1|root,COG3064@1|root,COG0484@2|Bacteria,COG3064@2|Bacteria,COG3706@2|Bacteria,1PEI3@1224|Proteobacteria,43A7R@68525|delta/epsilon subdivisions,2X3SX@28221|Deltaproteobacteria,2YX14@29|Myxococcales	28221|Deltaproteobacteria	OT	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
REGS1_k127_3620646_0	404589.Anae109_0770	1.588e-258	803.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2YU5P@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
REGS1_k127_3660612_6	204669.Acid345_2037	2.233e-06	57.0	2EETD@1|root,338KX@2|Bacteria,3Y5HI@57723|Acidobacteria,2JN5V@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3660612_5	1144275.COCOR_01921	2.557e-08	59.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria,2YXV7@29|Myxococcales	28221|Deltaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve,rve_3
REGS1_k127_3660612_3	404589.Anae109_1150	2.295e-45	173.0	COG1073@1|root,COG1073@2|Bacteria,1QYFN@1224|Proteobacteria,434P1@68525|delta/epsilon subdivisions,2WZ0B@28221|Deltaproteobacteria,2Z120@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3660612_4	886293.Sinac_5491	1.877e-39	149.0	COG0667@1|root,COG0667@2|Bacteria,2IXBS@203682|Planctomycetes	203682|Planctomycetes	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_3660612_1	243231.GSU2769	4.997e-70	249.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_3660612_2	1121015.N789_10820	1.182e-67	247.0	COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,1S4M7@1236|Gammaproteobacteria,1X6D4@135614|Xanthomonadales	135614|Xanthomonadales	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
REGS1_k127_3660612_0	290397.Adeh_0308	2.224e-95	332.0	COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,42U81@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_4
REGS1_k127_3662037_37	290397.Adeh_0048	1.301e-10	61.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2YVA5@29|Myxococcales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
REGS1_k127_3662037_10	404589.Anae109_0050	4.467e-125	407.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2YUPZ@29|Myxococcales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
REGS1_k127_3662037_11	404589.Anae109_0051	3.73e-115	379.0	COG0491@1|root,COG0491@2|Bacteria,1MUXF@1224|Proteobacteria,42QER@68525|delta/epsilon subdivisions,2WM9B@28221|Deltaproteobacteria,2Z2AM@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_3662037_14	404589.Anae109_0052	8.562e-112	366.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria,2YUTH@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
REGS1_k127_3662037_8	404589.Anae109_0057	3.004e-162	518.0	COG1236@1|root,COG1236@2|Bacteria,1MV7U@1224|Proteobacteria	1224|Proteobacteria	J	Exonuclease of the beta-lactamase fold involved in RNA processing	-	-	-	ko:K07577	-	-	-	-	ko00000	-	-	-	Lactamase_B_2
REGS1_k127_3662037_31	1195236.CTER_2595	1.664e-20	106.0	COG2768@1|root,COG2768@2|Bacteria,1UK08@1239|Firmicutes,25FG6@186801|Clostridia,3WK7Y@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_3662037_20	1009370.ALO_18015	1.198e-80	284.0	COG1456@1|root,COG1456@2|Bacteria,1TPYJ@1239|Firmicutes	1239|Firmicutes	C	CO dehydrogenase acetyl-CoA synthase delta subunit	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
REGS1_k127_3662037_9	290397.Adeh_0056	2.249e-148	475.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,430SK@68525|delta/epsilon subdivisions,2WW4G@28221|Deltaproteobacteria,2Z323@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
REGS1_k127_3662037_1	404589.Anae109_0060	0.0	1254.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YYWB@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 51	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
REGS1_k127_3662037_3	290397.Adeh_0058	9.574e-269	844.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
REGS1_k127_3662037_29	404589.Anae109_0062	9.359e-25	110.0	COG1826@1|root,COG1826@2|Bacteria,1PJQP@1224|Proteobacteria,4358S@68525|delta/epsilon subdivisions,2WZJX@28221|Deltaproteobacteria,2Z2A9@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	-	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_3662037_13	404589.Anae109_0063	2.53e-112	370.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2YVGX@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
REGS1_k127_3662037_38	483219.LILAB_16870	4.063e-10	69.0	2BRX3@1|root,32KXC@2|Bacteria,1Q30J@1224|Proteobacteria,433WX@68525|delta/epsilon subdivisions,2X8Z7@28221|Deltaproteobacteria,2YXHN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3662037_30	378806.STAUR_6549	1.27e-21	96.0	2AMRI@1|root,31CMV@2|Bacteria,1Q97Q@1224|Proteobacteria,4355D@68525|delta/epsilon subdivisions,2X95T@28221|Deltaproteobacteria,2Z22X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3662037_23	290397.Adeh_0064	9.812e-47	179.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
REGS1_k127_3662037_18	404589.Anae109_0067	1.213e-86	320.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
REGS1_k127_3662037_2	290397.Adeh_0066	9.968e-306	976.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,2YU1P@29|Myxococcales	28221|Deltaproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
REGS1_k127_3662037_4	404589.Anae109_0070	3.412e-244	760.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2YU21@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
REGS1_k127_3662037_16	290397.Adeh_0070	1.11e-90	303.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WPQK@28221|Deltaproteobacteria,2Z324@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
REGS1_k127_3662037_19	426355.Mrad2831_4878	4.074e-84	290.0	COG0596@1|root,COG0596@2|Bacteria,1N3G3@1224|Proteobacteria,2U1NS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
REGS1_k127_3662037_21	1242864.D187_004083	1.05e-77	280.0	COG0457@1|root,COG4676@1|root,COG0457@2|Bacteria,COG4676@2|Bacteria,1R4D7@1224|Proteobacteria,42PKH@68525|delta/epsilon subdivisions,2WK8N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3662037_28	290397.Adeh_0072	1.32e-29	135.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
REGS1_k127_3662037_6	290397.Adeh_0073	2.464e-201	637.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42N89@68525|delta/epsilon subdivisions,2WIUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PDZ DHR GLGF domain protein	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_3662037_22	404589.Anae109_0075	4e-74	257.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42R5Z@68525|delta/epsilon subdivisions,2WMPN@28221|Deltaproteobacteria,2YVXC@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
REGS1_k127_3662037_17	290397.Adeh_0076	1.365e-90	312.0	COG2071@1|root,COG2071@2|Bacteria,1MV8E@1224|Proteobacteria,43B6K@68525|delta/epsilon subdivisions,2X6K5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase C26	-	-	-	ko:K07010	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_C26
REGS1_k127_3662037_15	290397.Adeh_0077	2.33e-97	335.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2WK2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI,ThiP_synth
REGS1_k127_3662037_5	404589.Anae109_0078	9.257e-222	695.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2YTXF@29|Myxococcales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
REGS1_k127_3662037_40	1121440.AUMA01000008_gene878	1.538e-05	57.0	COG2304@1|root,COG2304@2|Bacteria,1PSXG@1224|Proteobacteria,435N6@68525|delta/epsilon subdivisions,2X01E@28221|Deltaproteobacteria,2M9QU@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3662037_24	404589.Anae109_0079	3.278e-46	186.0	COG5608@1|root,COG5608@2|Bacteria,1N4VR@1224|Proteobacteria	1224|Proteobacteria	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
REGS1_k127_3662037_0	404589.Anae109_0087	0.0	1803.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,42NHZ@68525|delta/epsilon subdivisions,2WJ2H@28221|Deltaproteobacteria,2YX1T@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine synthase	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
REGS1_k127_3662037_7	404589.Anae109_0088	2.532e-172	546.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,2Z30Q@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
REGS1_k127_3662037_36	717774.Marme_0378	7.065e-12	74.0	2DP4G@1|root,330H8@2|Bacteria,1NN5J@1224|Proteobacteria,1SECA@1236|Gammaproteobacteria,1XMQ7@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3662037_12	404380.Gbem_2356	2.907e-114	385.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_3662037_35	498211.CJA_1314	2.514e-12	77.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,1FGJH@10|Cellvibrio	1236|Gammaproteobacteria	S	ABC transporter	yjjK	GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_3666894_1	111780.Sta7437_0818	9.408e-06	54.0	COG0312@1|root,COG0312@2|Bacteria,1G43A@1117|Cyanobacteria,3VI3S@52604|Pleurocapsales	1117|Cyanobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_3666894_0	552811.Dehly_0371	3.757e-121	403.0	COG0312@1|root,COG0312@2|Bacteria,2GBVJ@200795|Chloroflexi,34CYG@301297|Dehalococcoidia	301297|Dehalococcoidia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_3682405_0	404589.Anae109_0729	1.798e-212	662.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YUKY@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_3682405_1	404589.Anae109_0728	7.08e-192	605.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
REGS1_k127_3682405_4	290397.Adeh_0683	4.791e-52	186.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_3682405_6	404589.Anae109_0726	1.34e-45	172.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	gspH	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02456,ko:K02457,ko:K02650	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	GspH,N_methyl
REGS1_k127_3682405_5	404589.Anae109_0725	6.504e-48	182.0	COG4967@1|root,COG4967@2|Bacteria,1QUS3@1224|Proteobacteria,42X07@68525|delta/epsilon subdivisions,2WSQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	gspI	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
REGS1_k127_3682405_3	404589.Anae109_0724	2.945e-67	245.0	COG4795@1|root,COG4795@2|Bacteria,1NPEC@1224|Proteobacteria,42WZG@68525|delta/epsilon subdivisions,2WSPB@28221|Deltaproteobacteria,2YVMW@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
REGS1_k127_3682405_2	290397.Adeh_0679	8.92e-102	357.0	COG3156@1|root,COG3156@2|Bacteria,1RIW9@1224|Proteobacteria,42V6H@68525|delta/epsilon subdivisions,2X2BW@28221|Deltaproteobacteria,2YVV7@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
REGS1_k127_3726060_2	215803.DB30_5321	5.639e-21	94.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PQQ_2,PQQ_3
REGS1_k127_3726060_1	1211579.PP4_14950	7.287e-26	115.0	2AP99@1|root,31EB9@2|Bacteria,1RM04@1224|Proteobacteria,1S5Z7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3726060_0	290397.Adeh_0736	0.0	1281.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2YU97@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
REGS1_k127_372790_1	404589.Anae109_3034	9.358e-124	402.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42NZI@68525|delta/epsilon subdivisions,2WIT8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	TIGRFAM ADP-ribosyl- dinitrogen reductase hydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
REGS1_k127_372790_2	404589.Anae109_3031	9.276e-52	190.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,42TNE@68525|delta/epsilon subdivisions,2WQI7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_372790_5	1173023.KE650771_gene4005	3.245e-05	53.0	2E67S@1|root,330W8@2|Bacteria,1G8CK@1117|Cyanobacteria,1JMUG@1189|Stigonemataceae	1117|Cyanobacteria	S	Nitrogen fixation protein NifW	nifW	-	-	ko:K02595	-	-	-	-	ko00000	-	-	-	NifW
REGS1_k127_372790_3	404589.Anae109_3025	9.609e-43	159.0	COG1149@1|root,COG1149@2|Bacteria,1QXPC@1224|Proteobacteria,42XYH@68525|delta/epsilon subdivisions,2WW0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	fdxN	-	-	-	-	-	-	-	-	-	-	-	Fer4_21,Fer4_7,Fer4_9
REGS1_k127_372790_4	404589.Anae109_3026	3.031e-35	155.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,42TMX@68525|delta/epsilon subdivisions,2WQJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
REGS1_k127_372790_0	404589.Anae109_3027	0.0	1030.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2WJF2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NifD NifK NifE NifN family	nifEN	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
REGS1_k127_3733572_9	290397.Adeh_2592	5.96e-44	175.0	COG3419@1|root,COG5184@1|root,COG3419@2|Bacteria,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
REGS1_k127_3733572_5	290397.Adeh_2591	1.807e-92	310.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
REGS1_k127_3733572_3	290397.Adeh_2590	1.831e-171	543.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2WKZB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
REGS1_k127_3733572_0	290397.Adeh_2588	4.729e-302	930.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
REGS1_k127_3733572_7	290397.Adeh_2587	1.446e-82	278.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,HTH_25
REGS1_k127_3733572_10	404589.Anae109_1274	4.176e-22	106.0	COG1286@1|root,COG1286@2|Bacteria	2|Bacteria	S	toxin biosynthetic process	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
REGS1_k127_3733572_2	290397.Adeh_3097	8.766e-192	602.0	COG1899@1|root,COG1899@2|Bacteria,1R3SU@1224|Proteobacteria,42P29@68525|delta/epsilon subdivisions,2WK0N@28221|Deltaproteobacteria,2YX3B@29|Myxococcales	28221|Deltaproteobacteria	O	Deoxyhypusine synthase	-	-	2.5.1.46	ko:K00809	-	-	-	-	ko00000,ko01000	-	-	-	DS
REGS1_k127_3733572_6	404589.Anae109_1277	5.127e-85	284.0	COG1959@1|root,COG1959@2|Bacteria,1Q19C@1224|Proteobacteria,4375I@68525|delta/epsilon subdivisions,2WRDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
REGS1_k127_3733572_4	404589.Anae109_1278	5.147e-122	396.0	COG0613@1|root,COG0613@2|Bacteria,1QV9S@1224|Proteobacteria,43BP1@68525|delta/epsilon subdivisions,2X70C@28221|Deltaproteobacteria,2YWF9@29|Myxococcales	28221|Deltaproteobacteria	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
REGS1_k127_3733572_1	404589.Anae109_1279	6.404e-222	700.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2YXGF@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
REGS1_k127_3733572_8	404589.Anae109_1280	1.048e-78	265.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YZAF@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
REGS1_k127_3764842_1	404589.Anae109_0163	4.177e-128	421.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WKPK@28221|Deltaproteobacteria,2Z316@29|Myxococcales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
REGS1_k127_3764842_3	404589.Anae109_0431	6.128e-96	323.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glycos_transf_2
REGS1_k127_3764842_0	404589.Anae109_0161	2.044e-268	836.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,42M83@68525|delta/epsilon subdivisions,2WIZE@28221|Deltaproteobacteria,2YXH5@29|Myxococcales	28221|Deltaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
REGS1_k127_3764842_2	404589.Anae109_0160	4.336e-113	376.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,1NFSV@1224|Proteobacteria,42PGP@68525|delta/epsilon subdivisions,2WMGP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KQ	Methyltransferase type 11	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5,Methyltransf_11
REGS1_k127_3770645_13	290397.Adeh_3594	1.973e-59	208.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
REGS1_k127_3770645_18	290397.Adeh_0651	6.017e-44	180.0	COG0457@1|root,COG0457@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
REGS1_k127_3770645_0	404589.Anae109_2974	1.005e-179	595.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WME2@28221|Deltaproteobacteria,2YWHE@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_3770645_7	404589.Anae109_3601	1.019e-108	359.0	COG1028@1|root,COG1028@2|Bacteria,1MW9A@1224|Proteobacteria,42ZSX@68525|delta/epsilon subdivisions,2WV17@28221|Deltaproteobacteria,2YZ2N@29|Myxococcales	28221|Deltaproteobacteria	IQ	reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_3770645_23	215803.DB30_0855	2.741e-21	103.0	COG0491@1|root,COG0491@2|Bacteria,1Q427@1224|Proteobacteria,439VM@68525|delta/epsilon subdivisions,2X59N@28221|Deltaproteobacteria,2Z0AV@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_3770645_1	243231.GSU2637	2.772e-166	554.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,43TCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_3770645_16	667014.Thein_1362	3.095e-50	188.0	COG0500@1|root,COG2226@2|Bacteria,2GIQ1@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
REGS1_k127_3770645_6	290397.Adeh_2156	1.082e-115	379.0	COG1718@1|root,COG1718@2|Bacteria,1N7US@1224|Proteobacteria,43BB3@68525|delta/epsilon subdivisions,2X6Q8@28221|Deltaproteobacteria,2YTY8@29|Myxococcales	28221|Deltaproteobacteria	DT	Serine threonine protein kinase involved in cell cycle control	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3770645_15	290397.Adeh_2155	1.084e-50	186.0	2CP0Z@1|root,32SI8@2|Bacteria,1RK5X@1224|Proteobacteria,434SF@68525|delta/epsilon subdivisions,2X904@28221|Deltaproteobacteria,2Z0HI@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
REGS1_k127_3770645_12	909663.KI867151_gene2967	6.504e-67	247.0	COG4191@1|root,COG4191@2|Bacteria,1PGQG@1224|Proteobacteria,439Y9@68525|delta/epsilon subdivisions,2X1VH@28221|Deltaproteobacteria,2MRRE@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_3770645_8	1121448.DGI_1064	4.619e-101	365.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2M7UM@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_3770645_14	903818.KI912268_gene2574	3.886e-57	203.0	COG1908@1|root,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	hdrG	-	-	-	-	-	-	-	-	-	-	-	FlpD
REGS1_k127_3770645_10	316067.Geob_3720	3.219e-75	269.0	COG0479@1|root,COG1035@1|root,COG0479@2|Bacteria,COG1035@2|Bacteria,1NQN7@1224|Proteobacteria,42MGI@68525|delta/epsilon subdivisions,2WKNC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	hdrD	-	-	-	-	-	-	-	-	-	-	-	Fer4_10,Fer4_17,Fer4_8,FlpD,FrhB_FdhB_C
REGS1_k127_3770645_20	269799.Gmet_3430	1.226e-31	142.0	COG1143@1|root,COG1143@2|Bacteria,1QVAQ@1224|Proteobacteria,43BPX@68525|delta/epsilon subdivisions,2X715@28221|Deltaproteobacteria,43V5C@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hdrE	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
REGS1_k127_3770645_11	316067.Geob_3719	1.527e-68	251.0	COG1143@1|root,COG1143@2|Bacteria,1QVAQ@1224|Proteobacteria,43BPX@68525|delta/epsilon subdivisions,2X715@28221|Deltaproteobacteria,43V5C@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hdrE	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
REGS1_k127_3770645_5	443144.GM21_0025	3.522e-126	424.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WKKC@28221|Deltaproteobacteria,43UVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	hdrF	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
REGS1_k127_3770645_4	693661.Arcve_1567	1.178e-142	487.0	COG1148@1|root,arCOG02235@2157|Archaea,2XT3X@28890|Euryarchaeota,245U1@183980|Archaeoglobi	183980|Archaeoglobi	C	Heterodisulfide reductase subunit A and related polyferredoxins	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_3770645_9	1265505.ATUG01000002_gene1615	2.272e-80	282.0	COG0247@1|root,COG1150@1|root,COG0247@2|Bacteria,COG1150@2|Bacteria,1MUMH@1224|Proteobacteria,42N5J@68525|delta/epsilon subdivisions,2WJ6B@28221|Deltaproteobacteria,2MJHX@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
REGS1_k127_3770645_3	452637.Oter_3677	1.265e-148	489.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,Pyr_redox_2
REGS1_k127_3770645_2	404589.Anae109_1591	1.857e-154	500.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2WJBJ@28221|Deltaproteobacteria,2YUMX@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1034	Acetate_kinase
REGS1_k127_3770645_19	1385935.N836_02520	2.563e-40	154.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_3770645_21	1078020.KEK_19908	5.215e-30	135.0	COG0204@1|root,COG0204@2|Bacteria,2GNBB@201174|Actinobacteria,2363I@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
REGS1_k127_3770645_17	290397.Adeh_2871	5.491e-45	170.0	COG3654@1|root,COG3654@2|Bacteria,1N1FW@1224|Proteobacteria,42V74@68525|delta/epsilon subdivisions,2WR7E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	ko:K07341	-	-	-	-	ko00000,ko02048	-	-	-	Fic
REGS1_k127_3770645_22	290397.Adeh_2870	4.469e-25	108.0	COG2336@1|root,COG2336@2|Bacteria	2|Bacteria	T	PFAM SpoVT AbrB	-	-	-	ko:K07172,ko:K18842	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
REGS1_k127_3772665_5	290397.Adeh_1152	1.854e-86	289.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Fic,Fic_N,HTH_34,ROK
REGS1_k127_3772665_8	404589.Anae109_1193	2.415e-21	96.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria	1224|Proteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
REGS1_k127_3772665_6	290397.Adeh_1146	3.53e-61	224.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WP90@28221|Deltaproteobacteria,2YVP3@29|Myxococcales	28221|Deltaproteobacteria	O	Alkyl hydroperoxide reductase	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	AhpC-TSA
REGS1_k127_3772665_7	290397.Adeh_1140	1.115e-58	207.0	COG1607@1|root,COG1607@2|Bacteria,1RAEQ@1224|Proteobacteria,42SPA@68525|delta/epsilon subdivisions,2WPPE@28221|Deltaproteobacteria,2YVJ2@29|Myxococcales	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_3772665_3	404589.Anae109_1187	1.137e-145	475.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2WN7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
REGS1_k127_3772665_0	404589.Anae109_1186	2.506e-238	776.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42QUN@68525|delta/epsilon subdivisions,2WN6Q@28221|Deltaproteobacteria,2YU60@29|Myxococcales	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
REGS1_k127_3772665_1	290397.Adeh_1137	3.48e-214	677.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
REGS1_k127_3772665_4	1121352.JHZP01000004_gene1578	3.636e-93	331.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,2VMSK@28216|Betaproteobacteria,2KPPA@206351|Neisseriales	206351|Neisseriales	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
REGS1_k127_3772665_2	290397.Adeh_1136	6.407e-178	567.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42MD7@68525|delta/epsilon subdivisions,2WJH1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
REGS1_k127_3784910_1	215803.DB30_7047	0.0	1138.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,2YUDK@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
REGS1_k127_3784910_0	215803.DB30_7048	0.0	1155.0	28N1D@1|root,2ZB7K@2|Bacteria,1R82F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3793365_3	1380600.AUYN01000010_gene946	2.787e-28	125.0	COG3209@1|root,COG3209@2|Bacteria,4NE5D@976|Bacteroidetes,1HYTK@117743|Flavobacteriia	976|Bacteroidetes	M	RHS repeat-associated core domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3793365_4	215803.DB30_5456	4.905e-09	67.0	COG0760@1|root,COG0760@2|Bacteria,1PK23@1224|Proteobacteria,43A0C@68525|delta/epsilon subdivisions,2X9PS@28221|Deltaproteobacteria,2YZAX@29|Myxococcales	28221|Deltaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
REGS1_k127_3793365_2	404589.Anae109_1750	1.908e-42	163.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_3793365_0	290397.Adeh_1262	6.282e-225	709.0	COG1052@1|root,COG1052@2|Bacteria,1REXX@1224|Proteobacteria,42R07@68525|delta/epsilon subdivisions,2X7JR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.310,1.1.1.399,1.1.1.95	ko:K00058,ko:K16843	ko00260,ko00270,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513,R05693	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
REGS1_k127_3793365_1	404589.Anae109_3064	5.903e-59	210.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
REGS1_k127_3811447_3	338966.Ppro_2064	2.765e-63	218.0	28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,42NVF@68525|delta/epsilon subdivisions,2WKNV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Fatty acid cis/trans isomerase (CTI)	-	-	-	-	-	-	-	-	-	-	-	-	CTI
REGS1_k127_3811447_4	1463920.JOGB01000016_gene5530	1.71e-11	70.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
REGS1_k127_3811447_1	404589.Anae109_0033	1.94e-121	402.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	fadL	-	-	ko:K06076	-	-	-	-	ko00000,ko02000	1.B.9	-	-	Toluene_X
REGS1_k127_3811447_0	290397.Adeh_0033	1.997e-138	480.0	COG1073@1|root,COG1073@2|Bacteria,1NVTC@1224|Proteobacteria,42Z2F@68525|delta/epsilon subdivisions,2WTUN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	COG1073 hydrolases of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_bact_N
REGS1_k127_3811447_2	1278073.MYSTI_04917	2.435e-76	264.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2X5RQ@28221|Deltaproteobacteria,2YYRW@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
REGS1_k127_381333_6	1242864.D187_008186	1.687e-65	244.0	COG0664@1|root,COG3266@1|root,COG0664@2|Bacteria,COG3266@2|Bacteria,1N1ZG@1224|Proteobacteria,4336W@68525|delta/epsilon subdivisions,2WYCK@28221|Deltaproteobacteria,2YZZW@29|Myxococcales	28221|Deltaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_381333_4	290397.Adeh_1675	2.145e-123	421.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,2YV6M@29|Myxococcales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284,ko:K16074	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3,1.A.35.4	-	-	CorA
REGS1_k127_381333_3	290397.Adeh_1674	1.966e-179	567.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
REGS1_k127_381333_2	290397.Adeh_1668	3.888e-205	664.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,43CC6@68525|delta/epsilon subdivisions,2X7N2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
REGS1_k127_381333_7	404589.Anae109_2141	1.414e-47	179.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria,2Z0X7@29|Myxococcales	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
REGS1_k127_381333_5	644966.Tmar_1086	2.094e-112	372.0	COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,24IX8@186801|Clostridia,3WDCB@538999|Clostridiales incertae sedis	186801|Clostridia	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
REGS1_k127_381333_1	525897.Dbac_1173	4.527e-250	778.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2M986@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751,ko:K17224	ko00230,ko00240,ko00760,ko00920,ko01100,ko01110,ko01120,map00230,map00240,map00760,map00920,map01100,map01110,map01120	M00595	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346,R10151	RC00017,RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	-	-	-	5_nucleotid_C,Metallophos
REGS1_k127_381333_0	261292.Nit79A3_1859	0.0	1152.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VNZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPase (P-type)	-	-	3.6.3.6	ko:K01535	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.3.3	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_3824217_0	697282.Mettu_0563	2.285e-245	768.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,1RX1M@1236|Gammaproteobacteria,1XG7H@135618|Methylococcales	135618|Methylococcales	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_3824217_1	381666.H16_B0376	4.857e-136	467.0	COG2114@1|root,COG3437@1|root,COG2114@2|Bacteria,COG3437@2|Bacteria,1QY14@1224|Proteobacteria,2WH9F@28216|Betaproteobacteria,1KBXM@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Belongs to the adenylyl cyclase class-4 guanylyl cyclase family	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,Response_reg
REGS1_k127_3824217_2	404589.Anae109_0250	3.611e-73	252.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WPZ9@28221|Deltaproteobacteria,2YV95@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_3824217_4	404589.Anae109_0251	8.813e-30	135.0	COG5662@1|root,COG5662@2|Bacteria	2|Bacteria	K	AntiSigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	zf-HC2
REGS1_k127_3824217_3	290397.Adeh_0233	1.129e-61	216.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,42S60@68525|delta/epsilon subdivisions,2WRAR@28221|Deltaproteobacteria,2Z3BB@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
REGS1_k127_3846049_1	404589.Anae109_0619	1.488e-130	422.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YUUX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_3846049_0	404589.Anae109_1024	0.0	1557.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
REGS1_k127_3846049_2	404589.Anae109_1023	6.54e-129	419.0	COG0845@1|root,COG0845@2|Bacteria,1MUFW@1224|Proteobacteria,42N4G@68525|delta/epsilon subdivisions,2WJ8A@28221|Deltaproteobacteria,2Z15D@29|Myxococcales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
REGS1_k127_384937_3	290397.Adeh_2547	6.682e-90	299.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2YU37@29|Myxococcales	28221|Deltaproteobacteria	C	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
REGS1_k127_384937_2	290397.Adeh_2546	2.16e-105	355.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,42RMJ@68525|delta/epsilon subdivisions,2WNP9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_384937_4	290397.Adeh_2545	1.235e-83	293.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Stage II sporulation D domain protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
REGS1_k127_384937_1	404589.Anae109_1319	4.361e-158	517.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria,2YUD8@29|Myxococcales	28221|Deltaproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
REGS1_k127_384937_0	290397.Adeh_2542	1.12e-202	638.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,2YU84@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
REGS1_k127_384937_7	404589.Anae109_1322	2.838e-27	128.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
REGS1_k127_384937_6	290397.Adeh_2540	3.929e-70	247.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2YU0A@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
REGS1_k127_3863020_8	290397.Adeh_2379	4.24e-54	191.0	COG5662@1|root,COG5662@2|Bacteria,1PC36@1224|Proteobacteria,4387X@68525|delta/epsilon subdivisions,2X3HP@28221|Deltaproteobacteria,2YW5D@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
REGS1_k127_3863020_5	290397.Adeh_2380	1.395e-113	388.0	COG0745@1|root,COG0745@2|Bacteria,1QXA6@1224|Proteobacteria,43E4U@68525|delta/epsilon subdivisions,2X7E9@28221|Deltaproteobacteria,2YVVM@29|Myxococcales	28221|Deltaproteobacteria	DKT	Response regulator receiver domain	frzS	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_3863020_0	290397.Adeh_2384	2.05e-228	727.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,2YVGD@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
REGS1_k127_3863020_1	404589.Anae109_1482	2.219e-161	538.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3863020_7	290397.Adeh_2386	1.163e-56	203.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
REGS1_k127_3863020_4	404589.Anae109_1480	1.942e-136	437.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2YTUR@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
REGS1_k127_3863020_3	404589.Anae109_1479	7.166e-140	482.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
REGS1_k127_3863020_2	290397.Adeh_2389	4.71e-140	448.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2YUYQ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
REGS1_k127_3863020_6	290397.Adeh_2390	3.398e-103	354.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2YXPT@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
REGS1_k127_3909726_0	1242864.D187_003480	4.67e-197	622.0	COG1429@1|root,COG1429@2|Bacteria,1QX7D@1224|Proteobacteria,43C0E@68525|delta/epsilon subdivisions,2X7B3@28221|Deltaproteobacteria,2Z3EW@29|Myxococcales	28221|Deltaproteobacteria	H	Glycosyl hydrolase family 63 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63
REGS1_k127_3909726_1	1496688.ER33_11555	3.243e-118	409.0	COG3408@1|root,COG3408@2|Bacteria,1G2AS@1117|Cyanobacteria,22THV@167375|Cyanobium	1117|Cyanobacteria	G	Amylo-alpha-1,6-glucosidase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
REGS1_k127_3946729_4	1469948.JPNB01000001_gene1360	2.312e-08	68.0	COG2247@1|root,COG2382@1|root,COG3210@1|root,COG5263@1|root,COG2247@2|Bacteria,COG2382@2|Bacteria,COG3210@2|Bacteria,COG5263@2|Bacteria,1UYJ9@1239|Firmicutes,248QE@186801|Clostridia,36KV6@31979|Clostridiaceae	186801|Clostridia	U	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CW_binding_1,LRR_5,SLH
REGS1_k127_3946729_0	404589.Anae109_3857	8.039e-50	182.0	COG3829@1|root,COG3829@2|Bacteria,1QVJM@1224|Proteobacteria,43CC9@68525|delta/epsilon subdivisions,2X7N5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
REGS1_k127_3946729_1	987059.RBXJA2T_10866	3.048e-41	158.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSKZ@28216|Betaproteobacteria,1KM38@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K03772,ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
REGS1_k127_3961428_0	290397.Adeh_2438	2.414e-181	578.0	COG1032@1|root,COG1032@2|Bacteria,1Q3ZA@1224|Proteobacteria,439T3@68525|delta/epsilon subdivisions,2X567@28221|Deltaproteobacteria,2Z064@29|Myxococcales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_3961428_3	290397.Adeh_2437	3.9e-50	178.0	COG2924@1|root,COG2924@2|Bacteria,1Q2JG@1224|Proteobacteria,433U0@68525|delta/epsilon subdivisions,2X9ZA@28221|Deltaproteobacteria,2YVYI@29|Myxococcales	28221|Deltaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
REGS1_k127_3961428_4	290397.Adeh_2436	2.748e-31	124.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
REGS1_k127_3961428_2	290397.Adeh_2435	1.306e-78	283.0	COG0745@1|root,COG0745@2|Bacteria	290397.Adeh_2435|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3961428_1	404589.Anae109_1445	1.29e-99	333.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2X5HK@28221|Deltaproteobacteria,2Z35S@29|Myxococcales	28221|Deltaproteobacteria	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
REGS1_k127_3986423_4	404589.Anae109_4207	3.689e-89	297.0	COG1060@1|root,COG1427@1|root,COG1060@2|Bacteria,COG1427@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2WJ6Y@28221|Deltaproteobacteria,2YZ18@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
REGS1_k127_3986423_2	404589.Anae109_4208	2.744e-134	439.0	COG0402@1|root,COG0402@2|Bacteria,1MVPA@1224|Proteobacteria,42MJ7@68525|delta/epsilon subdivisions,2WIRS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	PFAM amidohydrolase	-	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
REGS1_k127_3986423_6	159749.K0RDF3	1.136e-06	61.0	28JAF@1|root,2QRPA@2759|Eukaryota	2759|Eukaryota	S	structural constituent of cell wall	-	-	-	-	-	-	-	-	-	-	-	-	Fasciclin,HTH_psq,TSP_1,VWA
REGS1_k127_3986423_3	404589.Anae109_4209	2.691e-120	392.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,42MXH@68525|delta/epsilon subdivisions,2WK8E@28221|Deltaproteobacteria,2Z0NY@29|Myxococcales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
REGS1_k127_3986423_1	903818.KI912268_gene1911	4.725e-156	541.0	COG5373@1|root,COG5373@2|Bacteria	2|Bacteria	KLT	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF3999,LptC,NLPC_P60,SH3_3
REGS1_k127_3986423_0	903818.KI912268_gene1912	7.531e-191	623.0	COG5373@1|root,COG5373@2|Bacteria,3Y2GV@57723|Acidobacteria	57723|Acidobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
REGS1_k127_4001479_0	290397.Adeh_0606	4.5e-60	217.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria,2Z0DC@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
REGS1_k127_4014858_2	404589.Anae109_1337	5.191e-78	268.0	COG3075@1|root,COG3075@2|Bacteria,1MU3K@1224|Proteobacteria,42Q09@68525|delta/epsilon subdivisions,2WKE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein	glpB	-	1.1.5.3	ko:K00112	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2
REGS1_k127_4014858_6	404589.Anae109_1338	6.198e-30	126.0	COG1150@1|root,COG1150@2|Bacteria	2|Bacteria	C	4Fe-4S dicluster domain	-	-	1.17.1.9	ko:K00125,ko:K03646	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000,ko02000	2.C.1.2	-	-	Fer4,Fer4_17,Fer4_22,Fer4_8,FrhB_FdhB_C
REGS1_k127_4014858_1	290397.Adeh_2527	4.611e-115	379.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
REGS1_k127_4014858_5	269799.Gmet_0230	4.773e-49	179.0	COG2259@1|root,COG2259@2|Bacteria,1N072@1224|Proteobacteria,437CT@68525|delta/epsilon subdivisions,2XA0U@28221|Deltaproteobacteria,43VKC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
REGS1_k127_4014858_0	290397.Adeh_2524	0.0	1433.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,42SZ0@68525|delta/epsilon subdivisions,2WPIR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
REGS1_k127_4014858_4	472759.Nhal_3176	1.202e-65	228.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,1WYBM@135613|Chromatiales	135613|Chromatiales	S	PFAM Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
REGS1_k127_4014858_3	290397.Adeh_3704	5.601e-67	240.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,439XE@68525|delta/epsilon subdivisions,2X4RA@28221|Deltaproteobacteria,2YZFJ@29|Myxococcales	28221|Deltaproteobacteria	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
REGS1_k127_4030182_0	439235.Dalk_0629	1.65e-119	412.0	COG0001@1|root,COG1861@1|root,COG0001@2|Bacteria,COG1861@2|Bacteria,1MUY5@1224|Proteobacteria,42NVU@68525|delta/epsilon subdivisions,2WMH6@28221|Deltaproteobacteria,2MNBA@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Aminotransferase class-III	-	-	2.6.1.111,5.4.3.8	ko:K01845,ko:K07257,ko:K21585	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272,R11607	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
REGS1_k127_4030182_2	1121438.JNJA01000011_gene1820	1.316e-59	228.0	COG0001@1|root,COG1861@1|root,COG0001@2|Bacteria,COG1861@2|Bacteria,1MUY5@1224|Proteobacteria,42NVU@68525|delta/epsilon subdivisions,2WMH6@28221|Deltaproteobacteria,2MARK@213115|Desulfovibrionales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.111,5.4.3.8	ko:K01845,ko:K07257,ko:K21585	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272,R11607	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3,CTP_transf_3
REGS1_k127_4030182_1	439235.Dalk_0628	1.482e-66	239.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,42SMJ@68525|delta/epsilon subdivisions,2WPNK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_4039345_1	351016.RAZWK3B_14474	6.681e-09	61.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2TSJQ@28211|Alphaproteobacteria,2P472@2433|Roseobacter	28211|Alphaproteobacteria	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_4039345_0	1123504.JQKD01000008_gene5382	2.91e-147	486.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VNJM@28216|Betaproteobacteria,4ACQK@80864|Comamonadaceae	28216|Betaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,PP-binding
REGS1_k127_4039345_2	1078020.KEK_18839	0.0002177	44.0	COG4799@1|root,COG4799@2|Bacteria,2GNV2@201174|Actinobacteria,233IQ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	accD4_2	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
REGS1_k127_4042681_1	177437.HRM2_15040	1.049e-41	159.0	COG0745@1|root,COG4191@1|root,COG5002@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MI2B@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_8,PAS_9,Response_reg
REGS1_k127_4042681_0	404589.Anae109_1734	1.545e-119	399.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,42UVY@68525|delta/epsilon subdivisions,2WR44@28221|Deltaproteobacteria,2YVAT@29|Myxococcales	28221|Deltaproteobacteria	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
REGS1_k127_4042681_2	443143.GM18_3901	1.072e-39	157.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42M2V@68525|delta/epsilon subdivisions,2WKEB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNA methylase	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
REGS1_k127_404791_5	404589.Anae109_0699	2.743e-46	169.0	COG4775@1|root,COG4775@2|Bacteria,1RJPJ@1224|Proteobacteria,42TA2@68525|delta/epsilon subdivisions,2WP1H@28221|Deltaproteobacteria,2YZDW@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
REGS1_k127_404791_7	401053.AciPR4_3084	4.1e-16	83.0	2EK5Y@1|root,33DWC@2|Bacteria,3Y85Q@57723|Acidobacteria,2JP3V@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_404791_3	521674.Plim_2786	4.863e-52	193.0	COG4185@1|root,COG4185@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Zeta_toxin
REGS1_k127_404791_1	404589.Anae109_3588	9.569e-94	320.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria	1224|Proteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG_1	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
REGS1_k127_404791_0	290397.Adeh_4128	1.081e-98	334.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
REGS1_k127_404791_4	404589.Anae109_3587	3.051e-50	193.0	COG2096@1|root,COG2096@2|Bacteria,1RDUF@1224|Proteobacteria,42TN4@68525|delta/epsilon subdivisions,2WQ0Q@28221|Deltaproteobacteria,2YVM4@29|Myxococcales	28221|Deltaproteobacteria	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
REGS1_k127_404791_2	404589.Anae109_3586	5.72e-73	268.0	COG1181@1|root,COG1181@2|Bacteria,1QXU6@1224|Proteobacteria,43C6Q@68525|delta/epsilon subdivisions,2X7NN@28221|Deltaproteobacteria,2Z3H4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the D-alanine--D-alanine ligase family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4067891_3	290397.Adeh_0567	2.394e-160	515.0	COG0553@1|root,COG0553@2|Bacteria,1MX6H@1224|Proteobacteria,42QIF@68525|delta/epsilon subdivisions,2WKM9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNA polymerase recycling family C-terminal	rapA	-	-	ko:K03580	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	Helicase_C,RapA_C,SNF2_N
REGS1_k127_4067891_2	404589.Anae109_0611	9.744e-177	559.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,42MY5@68525|delta/epsilon subdivisions,2WKST@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase M20	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_4067891_7	1382306.JNIM01000001_gene1402	1.096e-34	148.0	COG1985@1|root,COG1985@2|Bacteria,2G97Y@200795|Chloroflexi	200795|Chloroflexi	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_4067891_13	671143.DAMO_0261	6.823e-12	71.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
REGS1_k127_4067891_6	398767.Glov_1131	2.35e-41	156.0	COG4679@1|root,COG4679@2|Bacteria,1MZC9@1224|Proteobacteria,42VAA@68525|delta/epsilon subdivisions,2WS9T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
REGS1_k127_4067891_12	1150626.PHAMO_470029	2.839e-25	111.0	COG5606@1|root,COG5606@2|Bacteria,1NBW2@1224|Proteobacteria,2UAP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
REGS1_k127_4067891_5	483219.LILAB_32395	9.475e-118	407.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	GUN4,GUN4_N,Peptidase_C13,Peptidase_C14
REGS1_k127_4067891_14	215803.DB30_0155	1.201e-10	72.0	COG5662@1|root,COG5662@2|Bacteria,1Q2KI@1224|Proteobacteria,43875@68525|delta/epsilon subdivisions,2X3H3@28221|Deltaproteobacteria,2YW29@29|Myxococcales	28221|Deltaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
REGS1_k127_4067891_9	1278073.MYSTI_05372	3.027e-29	124.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_4067891_4	290397.Adeh_0570	2.363e-120	391.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMP4@28221|Deltaproteobacteria,2YV9S@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
REGS1_k127_4067891_0	290397.Adeh_0571	1.474e-286	897.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1P2AZ@1224|Proteobacteria,4312R@68525|delta/epsilon subdivisions,2WWR3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_4067891_1	290397.Adeh_0572	9.097e-213	702.0	COG0745@1|root,COG0745@2|Bacteria,1P9P4@1224|Proteobacteria,43354@68525|delta/epsilon subdivisions,2WY4R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
REGS1_k127_4079535_1	765911.Thivi_2354	3.791e-38	148.0	2AMYE@1|root,31CVH@2|Bacteria,1NT8E@1224|Proteobacteria,1SMY1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4079535_2	68170.KL590473_gene4507	2.697e-14	79.0	2AMYE@1|root,31CVH@2|Bacteria,2GNQN@201174|Actinobacteria,4E5ZY@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4079535_0	215803.DB30_4431	1.044e-61	225.0	COG1964@1|root,COG1964@2|Bacteria,1QE02@1224|Proteobacteria,42M4B@68525|delta/epsilon subdivisions,2WJDI@28221|Deltaproteobacteria,2Z03B@29|Myxococcales	28221|Deltaproteobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
REGS1_k127_4111641_2	314278.NB231_16453	4.236e-47	171.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria,1SBYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_4111641_3	290397.Adeh_1899	1.516e-42	171.0	2DM7I@1|root,32UGD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4111641_4	1499967.BAYZ01000068_gene1935	1.545e-09	71.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
REGS1_k127_4111641_0	309799.DICTH_0179	3.965e-59	227.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K20952	ko05111,map05111	-	-	-	ko00000,ko00001	-	-	-	Beta-prism_lec,PQQ_2,PQQ_3,Pkinase,VCBS
REGS1_k127_4111641_1	1242864.D187_010064	4.519e-49	185.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
REGS1_k127_4111641_5	290397.Adeh_4049	4.856e-09	58.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
REGS1_k127_4117732_1	861299.J421_3350	3.612e-57	205.0	COG1703@1|root,COG1703@2|Bacteria,1ZT8J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
REGS1_k127_4117732_0	861299.J421_3349	2.098e-265	831.0	COG1884@1|root,COG1884@2|Bacteria,1ZUKS@142182|Gemmatimonadetes	142182|Gemmatimonadetes	I	Methylmalonyl-CoA mutase	-	-	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
REGS1_k127_4117732_2	932678.THERU_01720	8.862e-46	183.0	COG1503@1|root,COG1503@2|Bacteria	2|Bacteria	J	translation release factor activity	yocB	GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	-
REGS1_k127_4119629_4	290397.Adeh_0280	3.177e-137	439.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2YU4R@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
REGS1_k127_4119629_6	404589.Anae109_0305	1.249e-85	300.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2YV1Q@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
REGS1_k127_4119629_1	290397.Adeh_0285	1.372e-257	822.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,2YWSD@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
REGS1_k127_4119629_9	404589.Anae109_0312	5.406e-63	245.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_11,SBP_bac_6
REGS1_k127_4119629_12	290397.Adeh_0288	3.308e-47	173.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	citB	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	GerE
REGS1_k127_4119629_10	404589.Anae109_3066	1.405e-56	204.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	ybiI	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
REGS1_k127_4119629_8	1167006.UWK_00513	2.387e-70	268.0	COG1794@1|root,COG1794@2|Bacteria,1MV03@1224|Proteobacteria,42QQX@68525|delta/epsilon subdivisions,2WWFF@28221|Deltaproteobacteria,2MPFI@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
REGS1_k127_4119629_0	404589.Anae109_0315	5.413e-304	967.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,2YUJ3@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
REGS1_k127_4119629_15	234267.Acid_5986	4.247e-17	90.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	psrA	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_4119629_11	2074.JNYD01000001_gene6087	1.195e-55	221.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4DZ0E@85010|Pseudonocardiales	201174|Actinobacteria	GT	pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
REGS1_k127_4119629_16	529818.AMSG_10002T0	3.405e-13	79.0	KOG1215@1|root,KOG3607@1|root,KOG4348@1|root,KOG1215@2759|Eukaryota,KOG3607@2759|Eukaryota,KOG4348@2759|Eukaryota	2759|Eukaryota	S	negative regulation of transforming growth factor beta1 production	KMT2D	GO:0000003,GO:0001654,GO:0001667,GO:0001745,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005938,GO:0006928,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007423,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010564,GO:0010631,GO:0016020,GO:0016043,GO:0016477,GO:0017124,GO:0019904,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030029,GO:0030036,GO:0030100,GO:0030154,GO:0030496,GO:0030707,GO:0030855,GO:0032153,GO:0032154,GO:0032155,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032794,GO:0032879,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0040011,GO:0043062,GO:0043063,GO:0044085,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044459,GO:0044464,GO:0044703,GO:0045171,GO:0045177,GO:0045179,GO:0045216,GO:0045807,GO:0048259,GO:0048260,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048592,GO:0048609,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050839,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051302,GO:0051674,GO:0051704,GO:0051726,GO:0060429,GO:0060627,GO:0065007,GO:0071840,GO:0071944,GO:0090130,GO:0090132,GO:0090596,GO:0097435,GO:0098590,GO:0099568,GO:0099738	2.1.1.43,2.7.11.1	ko:K03068,ko:K06261,ko:K06593,ko:K08867,ko:K09187,ko:K12488,ko:K13738,ko:K14972,ko:K20050,ko:K20371	ko00310,ko04144,ko04150,ko04310,ko04512,ko04520,ko04611,ko04640,ko04666,ko04934,ko05100,ko05200,ko05224,ko05225,ko05226,map00310,map04144,map04150,map04310,map04512,map04520,map04611,map04640,map04666,map04934,map05100,map05200,map05224,map05225,map05226	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko01001,ko01009,ko03000,ko03036,ko04090,ko04131,ko04147,ko04516	-	-	-	Ig_3,Ldl_recept_a,SET,SH3_1,SH3_9,V-set
REGS1_k127_4119629_2	290397.Adeh_0291	2.285e-234	735.0	COG0464@1|root,COG0464@2|Bacteria,1MW4T@1224|Proteobacteria,42MBU@68525|delta/epsilon subdivisions,2WIJP@28221|Deltaproteobacteria,2YWW6@29|Myxococcales	28221|Deltaproteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	3.6.4.6	ko:K06027	ko04138,ko04721,ko04727,ko04962,map04138,map04721,map04727,map04962	-	-	-	ko00000,ko00001,ko01000,ko04131	1.F.1.1	-	-	AAA
REGS1_k127_4119629_7	324602.Caur_0670	3.643e-84	293.0	COG0482@1|root,COG0482@2|Bacteria,2G64I@200795|Chloroflexi,3751A@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
REGS1_k127_4119629_5	443143.GM18_0309	4.194e-91	338.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg,dCache_1
REGS1_k127_4119629_14	290397.Adeh_0292	6.044e-27	127.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
REGS1_k127_4119629_3	404589.Anae109_0318	2.113e-233	734.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
REGS1_k127_4119629_13	485915.Dret_0095	1.106e-38	158.0	COG3221@1|root,COG3221@2|Bacteria,1NPBT@1224|Proteobacteria,42R8P@68525|delta/epsilon subdivisions,2WMU5@28221|Deltaproteobacteria,2MGPT@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_4136162_4	864069.MicloDRAFT_00059320	1.295e-69	256.0	28NKC@1|root,2ZBM7@2|Bacteria,1MWMY@1224|Proteobacteria,2TU05@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	MA20_08580	-	-	-	-	-	-	-	-	-	-	-	Endostatin
REGS1_k127_4136162_2	404589.Anae109_3884	8.577e-176	581.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
REGS1_k127_4136162_3	404589.Anae109_3883	4.634e-134	474.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
REGS1_k127_4136162_0	290397.Adeh_3769	1.172e-192	610.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2YU89@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
REGS1_k127_4136162_1	290397.Adeh_3768	1.008e-190	600.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2YWXN@29|Myxococcales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
REGS1_k127_4136162_5	404589.Anae109_3880	6.729e-43	160.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2YXRU@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_4137891_9	404589.Anae109_3600	1.976e-37	144.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,2YW4G@29|Myxococcales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
REGS1_k127_4137891_5	290397.Adeh_3482	1.215e-73	260.0	COG0746@1|root,COG0746@2|Bacteria,1QXVT@1224|Proteobacteria,42U4M@68525|delta/epsilon subdivisions,2WQUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
REGS1_k127_4137891_10	290397.Adeh_3481	4.856e-33	130.0	COG4783@1|root,COG4783@2|Bacteria,1QYGM@1224|Proteobacteria,43CCT@68525|delta/epsilon subdivisions,2X7NP@28221|Deltaproteobacteria,2Z3H5@29|Myxococcales	28221|Deltaproteobacteria	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
REGS1_k127_4137891_1	404589.Anae109_3591	1.682e-132	434.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,42MA4@68525|delta/epsilon subdivisions,2WIPU@28221|Deltaproteobacteria,2Z1UM@29|Myxococcales	28221|Deltaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_4137891_4	290397.Adeh_3479	3.964e-77	265.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,2YVW4@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_4137891_8	404589.Anae109_3589	9.875e-54	191.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,431E6@68525|delta/epsilon subdivisions,2WWGA@28221|Deltaproteobacteria,2YVXB@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
REGS1_k127_4137891_3	404589.Anae109_0700	1.126e-80	289.0	COG4359@1|root,COG4359@2|Bacteria,1NMH7@1224|Proteobacteria,42UTM@68525|delta/epsilon subdivisions,2WQSI@28221|Deltaproteobacteria,2Z27X@29|Myxococcales	28221|Deltaproteobacteria	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.87	ko:K08966	ko00270,ko01100,map00270,map01100	M00034	R07394	RC02074	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD
REGS1_k127_4137891_2	290397.Adeh_0658	3.077e-128	417.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WQJT@28221|Deltaproteobacteria,2YV3J@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx GppA	gppA-1	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
REGS1_k127_4137891_0	290397.Adeh_0659	3.548e-164	540.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
REGS1_k127_4137891_7	290397.Adeh_0660	1.414e-54	206.0	COG0810@1|root,COG0810@2|Bacteria,1Q9SX@1224|Proteobacteria,42UPJ@68525|delta/epsilon subdivisions,2WQZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2
REGS1_k127_4137891_6	404589.Anae109_0705	3.956e-63	219.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2YVFC@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
REGS1_k127_4152471_16	404589.Anae109_2172	3.376e-55	198.0	COG0824@1|root,COG0824@2|Bacteria,1PEBE@1224|Proteobacteria,42TIA@68525|delta/epsilon subdivisions,2WQ9X@28221|Deltaproteobacteria,2Z33F@29|Myxococcales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
REGS1_k127_4152471_1	290397.Adeh_2728	1.439e-262	814.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,42MJX@68525|delta/epsilon subdivisions,2WJDM@28221|Deltaproteobacteria,2YUKX@29|Myxococcales	28221|Deltaproteobacteria	J	asparaginyl-tRNA synthetase	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
REGS1_k127_4152471_18	215803.DB30_0054	3.95e-32	142.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,42RF8@68525|delta/epsilon subdivisions,2WNSP@28221|Deltaproteobacteria,2YVG6@29|Myxococcales	28221|Deltaproteobacteria	T	Chemotaxis protein CheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
REGS1_k127_4152471_8	290397.Adeh_2730	6.027e-102	359.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,43AKW@68525|delta/epsilon subdivisions,2X60Z@28221|Deltaproteobacteria,2Z385@29|Myxococcales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
REGS1_k127_4152471_7	290397.Adeh_2731	1.737e-109	361.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,2YUW4@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
REGS1_k127_4152471_5	290397.Adeh_2732	3.488e-146	497.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PBS lyase	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
REGS1_k127_4152471_14	290397.Adeh_2733	8.711e-63	224.0	COG0835@1|root,COG0835@2|Bacteria,1N6GU@1224|Proteobacteria,42TH8@68525|delta/epsilon subdivisions,2WQV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	cheW40H-2	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_4152471_17	290397.Adeh_2734	3.012e-46	180.0	COG0835@1|root,COG0835@2|Bacteria,1PEGB@1224|Proteobacteria,43466@68525|delta/epsilon subdivisions,2X1U3@28221|Deltaproteobacteria,2YYW0@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_4152471_6	290397.Adeh_2735	4.582e-130	419.0	COG3267@1|root,COG3267@2|Bacteria,1REY9@1224|Proteobacteria,42RJB@68525|delta/epsilon subdivisions,2WN99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
REGS1_k127_4152471_0	290397.Adeh_2736	4.142e-284	887.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2YU8D@29|Myxococcales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric domain	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
REGS1_k127_4152471_13	290397.Adeh_2738	1.215e-63	220.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WRNH@28221|Deltaproteobacteria,2Z2ZZ@29|Myxococcales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
REGS1_k127_4152471_10	404589.Anae109_2728	5.277e-80	270.0	COG0054@1|root,COG0054@2|Bacteria,1RD9J@1224|Proteobacteria,42RQ6@68525|delta/epsilon subdivisions,2WNCZ@28221|Deltaproteobacteria,2YV53@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
REGS1_k127_4152471_3	404589.Anae109_2729	1.438e-221	705.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria,2YUHV@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
REGS1_k127_4152471_9	404589.Anae109_2730	2.299e-98	325.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,2YVMJ@29|Myxococcales	28221|Deltaproteobacteria	H	riboflavin synthase, alpha	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
REGS1_k127_4152471_4	404589.Anae109_2731	1.013e-168	542.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,2YUVJ@29|Myxococcales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
REGS1_k127_4152471_12	290397.Adeh_2743	2.515e-64	226.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2YVAV@29|Myxococcales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
REGS1_k127_4152471_2	290397.Adeh_2744	9.112e-234	740.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2YYIF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
REGS1_k127_4152471_11	404589.Anae109_2734	9.011e-70	238.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2WP1V@28221|Deltaproteobacteria,2Z0C3@29|Myxococcales	28221|Deltaproteobacteria	G	Ribose 5-phosphate isomerase	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1604	LacAB_rpiB
REGS1_k127_417137_1	404589.Anae109_1177	5.943e-68	243.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2YV0S@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
REGS1_k127_417137_0	357808.RoseRS_4105	2.447e-68	243.0	COG0411@1|root,COG0411@2|Bacteria,2GABI@200795|Chloroflexi,376AR@32061|Chloroflexia	32061|Chloroflexia	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_417137_2	1218173.BALCAV_0222085	2.864e-17	83.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,1ZBKN@1386|Bacillus	91061|Bacilli	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K11961	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
REGS1_k127_4177254_0	290397.Adeh_0766	1.141e-127	411.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PGQ@68525|delta/epsilon subdivisions,2WMJB@28221|Deltaproteobacteria,2YUUP@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
REGS1_k127_4177254_6	290397.Adeh_0765	5.873e-78	261.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WJWQ@28221|Deltaproteobacteria,2YV2V@29|Myxococcales	28221|Deltaproteobacteria	C	Rubrerythrin	rbr	GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_4177254_9	290397.Adeh_0761	1.963e-56	201.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,2Z1J6@29|Myxococcales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_4177254_3	404589.Anae109_0805	8.158e-100	338.0	COG2962@1|root,COG2962@2|Bacteria,1MX5G@1224|Proteobacteria,42QPT@68525|delta/epsilon subdivisions,2WN1M@28221|Deltaproteobacteria,2YV0R@29|Myxococcales	28221|Deltaproteobacteria	S	RarD protein	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
REGS1_k127_4177254_8	290397.Adeh_3961	4.491e-59	223.0	COG3850@1|root,COG3850@2|Bacteria,1N013@1224|Proteobacteria,42Z7D@68525|delta/epsilon subdivisions,2WURU@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
REGS1_k127_4177254_1	404589.Anae109_0790	1.79e-113	370.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,2YVC8@29|Myxococcales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
REGS1_k127_4177254_7	290397.Adeh_0752	1.308e-77	292.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,42S5S@68525|delta/epsilon subdivisions,2WNSS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
REGS1_k127_4177254_5	404589.Anae109_0788	4.065e-84	284.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2Z0FU@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
REGS1_k127_4177254_4	290397.Adeh_0747	2.362e-96	330.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42N2T@68525|delta/epsilon subdivisions,2WMYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_4177254_10	290397.Adeh_0739	2.409e-39	147.0	COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,42XZS@68525|delta/epsilon subdivisions,2WSXJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
REGS1_k127_4177254_2	215803.DB30_5321	9.097e-110	364.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HYR,PQQ_2,PQQ_3
REGS1_k127_417856_3	404589.Anae109_3810	1.123e-97	336.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria	1224|Proteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
REGS1_k127_417856_5	926550.CLDAP_03370	2.561e-58	214.0	COG3221@1|root,COG3221@2|Bacteria,2G79Q@200795|Chloroflexi	200795|Chloroflexi	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_417856_6	882.DVU_0119	4.435e-45	183.0	COG4191@1|root,COG4191@2|Bacteria,1Q87X@1224|Proteobacteria,42Q2K@68525|delta/epsilon subdivisions,2WJTQ@28221|Deltaproteobacteria,2MG0U@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Single cache domain 3	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_2
REGS1_k127_417856_2	290397.Adeh_3685	1.07e-120	411.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,2Z0N2@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
REGS1_k127_417856_1	290397.Adeh_3687	2.257e-178	567.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_417856_0	290397.Adeh_3688	4.723e-222	711.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1NVZF@1224|Proteobacteria,42ZUK@68525|delta/epsilon subdivisions,2X7NR@28221|Deltaproteobacteria,2Z3H7@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,Response_reg
REGS1_k127_417856_4	404589.Anae109_3815	9.433e-89	302.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
REGS1_k127_418477_4	401053.AciPR4_0845	8.527e-09	68.0	COG0412@1|root,COG0412@2|Bacteria,3Y4CQ@57723|Acidobacteria,2JJ5E@204432|Acidobacteriia	204432|Acidobacteriia	Q	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_418477_3	272568.GDI0501	9.875e-11	73.0	COG0535@1|root,COG0535@2|Bacteria,1Q8U2@1224|Proteobacteria,2UYJA@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_418477_2	215803.DB30_1401	1.253e-41	178.0	COG0535@1|root,COG0535@2|Bacteria,1R9I5@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
REGS1_k127_418477_0	404589.Anae109_1857	1.958e-112	397.0	COG2374@1|root,COG2374@2|Bacteria,1RA34@1224|Proteobacteria,42XZM@68525|delta/epsilon subdivisions,2WT9C@28221|Deltaproteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3616)	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_418477_5	443144.GM21_3564	2.48e-07	64.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_418477_1	290397.Adeh_0690	1.045e-41	153.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,2YYQJ@29|Myxococcales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
REGS1_k127_4221181_0	234267.Acid_5684	3.702e-99	341.0	COG0649@1|root,COG0649@2|Bacteria,3Y3AB@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
REGS1_k127_4221181_2	1187851.A33M_4049	1.967e-39	157.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2TSMT@28211|Alphaproteobacteria,3FCZ4@34008|Rhodovulum	28211|Alphaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
REGS1_k127_4221181_1	1340493.JNIF01000003_gene4205	5.248e-71	244.0	COG0377@1|root,COG0377@2|Bacteria,3Y3JS@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
REGS1_k127_4221181_3	1121918.ARWE01000001_gene279	9.554e-32	127.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42UPV@68525|delta/epsilon subdivisions,2WQB6@28221|Deltaproteobacteria,43UXF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
REGS1_k127_4278714_0	290397.Adeh_3184	0.0	1023.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2YV3K@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_429653_8	404589.Anae109_4206	6.355e-31	132.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,2YYN9@29|Myxococcales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
REGS1_k127_429653_6	290397.Adeh_0373	3.135e-79	282.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2WP9I@28221|Deltaproteobacteria,2Z0YH@29|Myxococcales	28221|Deltaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3392	Flavoprotein
REGS1_k127_429653_5	404589.Anae109_4204	4.868e-106	372.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2YU8C@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
REGS1_k127_429653_0	404589.Anae109_4203	8.834e-283	873.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,42MGF@68525|delta/epsilon subdivisions,2WJMB@28221|Deltaproteobacteria,2Z05N@29|Myxococcales	28221|Deltaproteobacteria	H	3-octaprenyl-4-hydroxybenzoate carboxy-lyase	-	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
REGS1_k127_429653_3	290397.Adeh_2132	2.678e-139	451.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439EA@68525|delta/epsilon subdivisions,2X4PC@28221|Deltaproteobacteria,2YZCI@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
REGS1_k127_429653_7	290397.Adeh_2133	1.011e-64	253.0	COG2846@1|root,COG2846@2|Bacteria,1MVCQ@1224|Proteobacteria,42NXK@68525|delta/epsilon subdivisions,2WMGN@28221|Deltaproteobacteria,2Z0I9@29|Myxococcales	28221|Deltaproteobacteria	C	Di-iron-containing protein involved in the repair of iron-sulfur clusters	scdA	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	Hemerythrin,ScdA_N
REGS1_k127_429653_2	404589.Anae109_3145	3.43e-144	465.0	COG2461@1|root,COG2461@2|Bacteria,1R5J5@1224|Proteobacteria,42QAZ@68525|delta/epsilon subdivisions,2WQTR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	Hemerythrin,PAS_10
REGS1_k127_429653_4	404589.Anae109_4173	1.211e-121	395.0	COG1018@1|root,COG1018@2|Bacteria,1MW37@1224|Proteobacteria,432D0@68525|delta/epsilon subdivisions,2WY0P@28221|Deltaproteobacteria,2Z211@29|Myxococcales	28221|Deltaproteobacteria	C	Oxidoreductase NAD-binding domain	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	FAD_binding_6,NAD_binding_1
REGS1_k127_429653_1	290397.Adeh_2157	5.919e-178	561.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YUEB@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_4298880_3	1123368.AUIS01000005_gene429	3.855e-09	59.0	COG1704@1|root,COG1704@2|Bacteria,1R9YG@1224|Proteobacteria,1T06D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
REGS1_k127_4298880_2	215803.DB30_4272	1.68e-43	168.0	COG0399@1|root,COG0515@1|root,COG0399@2|Bacteria,COG0515@2|Bacteria,1MUMJ@1224|Proteobacteria,43BZX@68525|delta/epsilon subdivisions,2X7AP@28221|Deltaproteobacteria,2YXNP@29|Myxococcales	28221|Deltaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
REGS1_k127_4298880_1	1444309.JAQG01000027_gene4086	7.893e-58	211.0	COG0500@1|root,COG2226@2|Bacteria,1UF5I@1239|Firmicutes,4IQGV@91061|Bacilli,272QK@186822|Paenibacillaceae	91061|Bacilli	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_4298880_0	1380393.JHVP01000004_gene614	1.552e-175	569.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4ERPW@85013|Frankiales	201174|Actinobacteria	KOT	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
REGS1_k127_4330814_3	404589.Anae109_2946	1.2e-68	241.0	COG3897@1|root,COG3897@2|Bacteria,1N9VC@1224|Proteobacteria,435VU@68525|delta/epsilon subdivisions,2X0BN@28221|Deltaproteobacteria,2Z0RC@29|Myxococcales	28221|Deltaproteobacteria	S	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	-	-	-	-	-	-	-	-	-	PrmA
REGS1_k127_4330814_0	404589.Anae109_0257	1.28e-259	807.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,2YWA3@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
REGS1_k127_4330814_2	404589.Anae109_0258	5.858e-94	314.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2YVCY@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
REGS1_k127_4330814_1	290397.Adeh_0237	1.519e-99	341.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria,2YTXM@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19,TPR_8,Transglut_core
REGS1_k127_4345240_1	290397.Adeh_1054	3.727e-158	525.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,2YU71@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
REGS1_k127_4345240_0	404589.Anae109_1105	1.4e-240	750.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_4345240_2	404589.Anae109_1109	8.079e-110	359.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,42KZX@68525|delta/epsilon subdivisions,2WM2N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
REGS1_k127_4359325_7	1278073.MYSTI_02208	3.269e-10	74.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,2YYW2@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
REGS1_k127_4359325_5	290397.Adeh_1311	2.809e-72	247.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WS27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
REGS1_k127_4359325_2	404589.Anae109_2452	1.685e-128	450.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,RsbRD_N,SBP_bac_3
REGS1_k127_4359325_3	290397.Adeh_1068	1.554e-112	370.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,42Q5T@68525|delta/epsilon subdivisions,2WUTJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
REGS1_k127_4359325_4	215803.DB30_3014	6.546e-75	265.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,43BTG@68525|delta/epsilon subdivisions,2X74B@28221|Deltaproteobacteria,2Z3ED@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
REGS1_k127_4359325_1	290397.Adeh_1313	7.728e-176	566.0	COG1466@1|root,COG1466@2|Bacteria,1RAEB@1224|Proteobacteria,42R0X@68525|delta/epsilon subdivisions,2WMQJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III, delta'	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
REGS1_k127_4359325_0	290397.Adeh_1314	0.0	1058.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,2YU6M@29|Myxococcales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
REGS1_k127_4359325_6	404589.Anae109_2448	4.725e-30	119.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,2YUWH@29|Myxococcales	28221|Deltaproteobacteria	L	TatD family	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
REGS1_k127_436010_4	404589.Anae109_3694	7.768e-19	91.0	COG0457@1|root,COG0457@2|Bacteria,1MYB8@1224|Proteobacteria,42P5H@68525|delta/epsilon subdivisions,2WKAU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8
REGS1_k127_436010_0	290397.Adeh_3575	6.394e-146	465.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42T24@68525|delta/epsilon subdivisions,2WPF8@28221|Deltaproteobacteria,2YV09@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
REGS1_k127_436010_2	290397.Adeh_3578	1.139e-57	207.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2Z0M6@29|Myxococcales	28221|Deltaproteobacteria	C	Semialdehyde dehydrogenase, NAD binding domain	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_4397023_1	290397.Adeh_3676	5.632e-61	213.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,2YU1K@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2638	PEPCK_C,PEPCK_N
REGS1_k127_4397023_0	290397.Adeh_3677	1.004e-96	321.0	COG3332@1|root,COG3332@2|Bacteria,1PUN1@1224|Proteobacteria,434TB@68525|delta/epsilon subdivisions,2WZ4B@28221|Deltaproteobacteria,2Z1AV@29|Myxococcales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
REGS1_k127_4397023_2	404589.Anae109_3805	6.912e-36	138.0	COG3536@1|root,COG3536@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF971)	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	DUF971
REGS1_k127_4397023_4	1211813.CAPH01000003_gene1386	2.003e-20	100.0	2FK1S@1|root,34BPZ@2|Bacteria,4P558@976|Bacteroidetes,2FYSJ@200643|Bacteroidia	976|Bacteroidetes	S	Bacterial protein of unknown function (YtfJ_HI0045)	-	-	-	ko:K07109	-	-	-	-	ko00000	-	-	-	YtfJ_HI0045
REGS1_k127_440303_1	439235.Dalk_0572	8.475e-78	284.0	COG0745@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,2MI2B@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
REGS1_k127_440303_2	404589.Anae109_1376	1.114e-74	278.0	COG1587@1|root,COG1587@2|Bacteria,1QYG8@1224|Proteobacteria,43CCC@68525|delta/epsilon subdivisions,2X7NB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
REGS1_k127_440303_0	290397.Adeh_2492	7.353e-161	510.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2YUZ3@29|Myxococcales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
REGS1_k127_440303_3	290397.Adeh_2493	3.99e-61	214.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2YWEM@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
REGS1_k127_4429665_11	290397.Adeh_2700	2.98e-14	86.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2YVFF@29|Myxococcales	28221|Deltaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
REGS1_k127_4429665_3	404589.Anae109_2695	6.301e-143	464.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42TT7@68525|delta/epsilon subdivisions,2WQR1@28221|Deltaproteobacteria,2Z2YV@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
REGS1_k127_4429665_9	290397.Adeh_2702	1.283e-49	185.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
REGS1_k127_4429665_6	290397.Adeh_2703	8.095e-90	325.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2YVJ7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
REGS1_k127_4429665_4	404589.Anae109_2699	2.231e-117	402.0	COG0745@1|root,COG1196@1|root,COG0745@2|Bacteria,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	Response_reg
REGS1_k127_4429665_0	290397.Adeh_2714	7.317e-213	664.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2YXJE@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_4429665_5	290397.Adeh_2715	5.986e-110	382.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
REGS1_k127_4429665_8	290397.Adeh_2158	7.02e-50	195.0	COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,42V0Z@68525|delta/epsilon subdivisions,2WSQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Putative thioesterase (yiiD_Cterm)	-	-	-	-	-	-	-	-	-	-	-	-	YiiD_C
REGS1_k127_4429665_7	1123508.JH636442_gene3982	7.333e-67	232.0	COG0432@1|root,COG0432@2|Bacteria,2IZ7Q@203682|Planctomycetes	203682|Planctomycetes	S	PFAM Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
REGS1_k127_4429665_2	404589.Anae109_2708	1.056e-160	512.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,2YU17@29|Myxococcales	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_4429665_1	404589.Anae109_2709	2.246e-199	641.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2YVAG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
REGS1_k127_4432680_5	398512.JQKC01000004_gene5249	1.065e-101	369.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1UIEA@1239|Firmicutes,25EJM@186801|Clostridia,3WI29@541000|Ruminococcaceae	186801|Clostridia	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_4432680_11	391625.PPSIR1_14455	8.832e-30	128.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
REGS1_k127_4432680_10	378806.STAUR_7408	4.78e-51	186.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,42TBH@68525|delta/epsilon subdivisions,2WPJ5@28221|Deltaproteobacteria,2YW2S@29|Myxococcales	28221|Deltaproteobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
REGS1_k127_4432680_8	1499967.BAYZ01000009_gene5260	1.893e-56	203.0	2AY4N@1|root,31Q6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4432680_9	404589.Anae109_2428	3.981e-53	195.0	COG3945@1|root,COG3945@2|Bacteria,1NG3G@1224|Proteobacteria,42WHU@68525|delta/epsilon subdivisions,2WRK5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
REGS1_k127_4432680_3	1242864.D187_005732	2.602e-103	339.0	COG0702@1|root,COG0702@2|Bacteria,1QR3E@1224|Proteobacteria,4341F@68525|delta/epsilon subdivisions,2X4MP@28221|Deltaproteobacteria,2YZ9G@29|Myxococcales	28221|Deltaproteobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_4432680_13	604331.AUHY01000038_gene136	0.0005274	48.0	2DGZ3@1|root,2ZXUD@2|Bacteria,1WKRC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_4432680_12	1123386.AUIW01000009_gene1812	8.472e-24	111.0	COG1848@1|root,COG1848@2|Bacteria,1WKJ4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4432680_4	935948.KE386495_gene1092	1.156e-102	359.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,42FC3@68295|Thermoanaerobacterales	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppF	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
REGS1_k127_4432680_1	867903.ThesuDRAFT_02277	3.564e-116	404.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WCCK@538999|Clostridiales incertae sedis	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
REGS1_k127_4432680_6	1168065.DOK_04172	1.93e-94	340.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,1RND6@1236|Gammaproteobacteria,1J8YE@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	oppC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iAF1260.b1245,iB21_1397.B21_01229,iEC55989_1330.EC55989_1342,iECBD_1354.ECBD_2377,iECB_1328.ECB_01219,iECDH10B_1368.ECDH10B_1307,iECDH1ME8569_1439.ECDH1ME8569_1185,iECD_1391.ECD_01219,iECIAI1_1343.ECIAI1_1264,iECO103_1326.ECO103_1345,iECO111_1330.ECO111_1572,iECO26_1355.ECO26_1756,iECSE_1348.ECSE_1293,iECSP_1301.ECSP_1637,iECUMN_1333.ECUMN_1542,iECW_1372.ECW_m1337,iECs_1301.ECs1745,iEKO11_1354.EKO11_2607,iETEC_1333.ETEC_1347,iEcDH1_1363.EcDH1_2403,iEcE24377_1341.EcE24377A_1393,iEcHS_1320.EcHS_A1354,iEcolC_1368.EcolC_2383,iG2583_1286.G2583_1517,iJO1366.b1245,iSSON_1240.SSON_1935,iUMNK88_1353.UMNK88_1565,iWFL_1372.ECW_m1337,iY75_1357.Y75_RS06515,iZ_1308.Z2021	BPD_transp_1,OppC_N
REGS1_k127_4432680_2	1123279.ATUS01000004_gene2857	3.655e-112	389.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,1RNJ1@1236|Gammaproteobacteria,1J8N0@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	EP	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	oppB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
REGS1_k127_4432680_0	1168065.DOK_04162	6.871e-140	455.0	COG4166@1|root,COG4166@2|Bacteria,1P91R@1224|Proteobacteria,1RN57@1236|Gammaproteobacteria,1J7I8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	COG4166 ABC-type oligopeptide transport system, periplasmic component	oppA	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	iECABU_c1320.ECABU_c15240,iECNA114_1301.ECNA114_1414,iECSF_1327.ECSF_1224,iNRG857_1313.NRG857_06385,iUMNK88_1353.UMNK88_1667	SBP_bac_5
REGS1_k127_446991_2	404589.Anae109_1308	2.326e-71	244.0	COG1624@1|root,COG1624@2|Bacteria,1N12B@1224|Proteobacteria,42UVR@68525|delta/epsilon subdivisions,2WQ2R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
REGS1_k127_446991_3	290397.Adeh_2554	1.227e-61	215.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria,2YVJ6@29|Myxococcales	28221|Deltaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
REGS1_k127_446991_1	290397.Adeh_2553	3.102e-85	317.0	COG1716@1|root,COG1716@2|Bacteria,1Q2GC@1224|Proteobacteria,4382T@68525|delta/epsilon subdivisions,2X0C6@28221|Deltaproteobacteria,2YVG7@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
REGS1_k127_446991_0	1144275.COCOR_02951	9.158e-101	361.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
REGS1_k127_4480646_1	404589.Anae109_3383	8.488e-262	822.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
REGS1_k127_4480646_2	290397.Adeh_3321	6.336e-113	383.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_3321|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4480646_0	404589.Anae109_3386	1.41e-280	880.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
REGS1_k127_4500440_8	1047013.AQSP01000073_gene1092	1.399e-05	57.0	COG1305@1|root,COG3391@1|root,COG1305@2|Bacteria,COG3391@2|Bacteria,2NQ2D@2323|unclassified Bacteria	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Transglut_core
REGS1_k127_4500440_9	595536.ADVE02000001_gene3474	9.515e-05	50.0	COG1468@1|root,COG1518@1|root,COG1468@2|Bacteria,COG1518@2|Bacteria,1MUKK@1224|Proteobacteria,2TS91@28211|Alphaproteobacteria,370HN@31993|Methylocystaceae	28211|Alphaproteobacteria	L	CRISPR associated protein Cas1	-	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1,Cas_Cas4
REGS1_k127_4500440_4	1463901.JOIY01000002_gene969	1.781e-29	137.0	COG0515@1|root,COG0515@2|Bacteria,2HMAN@201174|Actinobacteria	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
REGS1_k127_4500440_6	1396141.BATP01000060_gene4646	1.832e-14	82.0	COG1595@1|root,COG1595@2|Bacteria,46VAN@74201|Verrucomicrobia,2IUN6@203494|Verrucomicrobiae	74201|Verrucomicrobia	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_ECF
REGS1_k127_4500440_2	452637.Oter_0998	8.547e-72	258.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_4500440_0	246194.CHY_1735	5.38e-160	524.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,42FN9@68295|Thermoanaerobacterales	186801|Clostridia	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
REGS1_k127_4500440_3	886293.Sinac_3643	2.711e-49	202.0	COG0451@1|root,COG0451@2|Bacteria,2IX97@203682|Planctomycetes	203682|Planctomycetes	M	PFAM 3-beta hydroxysteroid dehydrogenase isomerase	-	-	1.1.1.412	ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
REGS1_k127_4500440_1	164757.Mjls_3425	1.151e-73	261.0	COG0332@1|root,COG0332@2|Bacteria,2I9C8@201174|Actinobacteria,23EW9@1762|Mycobacteriaceae	201174|Actinobacteria	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_4500440_5	1206732.BAGD01000106_gene4895	4.933e-23	115.0	COG0332@1|root,COG0332@2|Bacteria,2IK61@201174|Actinobacteria,4FXDQ@85025|Nocardiaceae	201174|Actinobacteria	I	synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_4501564_12	215803.DB30_4352	7.399e-08	59.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2YU7W@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
REGS1_k127_4501564_0	404589.Anae109_4163	1.036e-204	644.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,42N7F@68525|delta/epsilon subdivisions,2WJB2@28221|Deltaproteobacteria,2YUH3@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the thiolase family	fadI	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_4501564_9	290397.Adeh_3147	2.143e-53	204.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
REGS1_k127_4501564_3	404589.Anae109_4165	7.822e-168	531.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
REGS1_k127_4501564_5	1121918.ARWE01000001_gene3559	7.922e-136	458.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,PocR,Response_reg,dCache_1,sCache_2
REGS1_k127_4501564_4	404589.Anae109_4166	6.524e-162	514.0	COG4586@1|root,COG4586@2|Bacteria,1RA7G@1224|Proteobacteria,42RT3@68525|delta/epsilon subdivisions,2WNGM@28221|Deltaproteobacteria,2YU3C@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_4501564_10	290397.Adeh_0445	4.173e-49	181.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
REGS1_k127_4501564_8	251221.35210611	8.009e-83	301.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	natB	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	iYO844.BSU02760	ABC2_membrane_2,ABC2_membrane_3
REGS1_k127_4501564_7	1278073.MYSTI_07425	7.569e-88	318.0	COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,43BX9@68525|delta/epsilon subdivisions,2X782@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	ABC transporter	natA	-	3.6.3.7	ko:K09697	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.115	-	-	ABC_tran
REGS1_k127_4501564_6	1500890.JQNL01000001_gene2318	4.861e-100	343.0	COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,1RNTQ@1236|Gammaproteobacteria,1X2Y2@135614|Xanthomonadales	135614|Xanthomonadales	I	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
REGS1_k127_4501564_1	290397.Adeh_0403	1.04e-176	582.0	COG5459@1|root,COG5459@2|Bacteria,1MWMM@1224|Proteobacteria,42WIB@68525|delta/epsilon subdivisions,2WRHR@28221|Deltaproteobacteria,2Z341@29|Myxococcales	28221|Deltaproteobacteria	J	Mitochondrial small ribosomal subunit Rsm22	-	-	-	-	-	-	-	-	-	-	-	-	Rsm22
REGS1_k127_4501564_2	290397.Adeh_1677	2.125e-171	546.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2YX9Q@29|Myxococcales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
REGS1_k127_4501861_0	290397.Adeh_3847	1.045e-109	370.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42UNC@68525|delta/epsilon subdivisions	1224|Proteobacteria	I	TAP-like protein	catD	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,SnoaL_2
REGS1_k127_4501861_2	215803.DB30_7092	3.921e-13	75.0	2AK94@1|root,31AZD@2|Bacteria,1Q6KJ@1224|Proteobacteria,439D5@68525|delta/epsilon subdivisions,2X4MU@28221|Deltaproteobacteria,2YZ9M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4502696_18	378806.STAUR_3894	1.119e-10	62.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	Gly-zipper_Omp,OmpA,TSP_3
REGS1_k127_4502696_7	378806.STAUR_3895	2.955e-63	226.0	COG4932@1|root,COG5184@1|root,COG4932@2|Bacteria,COG5184@2|Bacteria,1R85W@1224|Proteobacteria	1224|Proteobacteria	M	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Big_5,DUF3494,VPEP
REGS1_k127_4502696_2	1192034.CAP_6879	1.528e-104	352.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MG3@68525|delta/epsilon subdivisions,2WKC7@28221|Deltaproteobacteria,2Z0CT@29|Myxococcales	28221|Deltaproteobacteria	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE,STAS_2
REGS1_k127_4502696_6	1192034.CAP_6880	2.679e-81	295.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WKHW@28221|Deltaproteobacteria,2Z0Q4@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
REGS1_k127_4502696_9	1192034.CAP_6881	2.956e-56	218.0	COG1463@1|root,COG1463@2|Bacteria,1PV9I@1224|Proteobacteria,43EXS@68525|delta/epsilon subdivisions,2X225@28221|Deltaproteobacteria,2Z2A7@29|Myxococcales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K06192	-	-	-	-	ko00000	-	-	-	MlaD
REGS1_k127_4502696_4	56780.SYN_02721	8.143e-95	335.0	COG2206@1|root,COG5000@1|root,COG2206@2|Bacteria,COG5000@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2MSKQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HAMP,HD,HD_5
REGS1_k127_4502696_19	316067.Geob_2397	7.611e-09	68.0	2BX4M@1|root,2ZKVT@2|Bacteria,1P6KE@1224|Proteobacteria,4331W@68525|delta/epsilon subdivisions,2WYFI@28221|Deltaproteobacteria,43VNM@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4502696_1	290397.Adeh_3181	1.112e-155	520.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42YYA@68525|delta/epsilon subdivisions,2WTU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
REGS1_k127_4502696_11	404380.Gbem_3095	8.761e-43	171.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,42S2Z@68525|delta/epsilon subdivisions,2X5JB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
REGS1_k127_4502696_0	404589.Anae109_3191	9.546e-199	633.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
REGS1_k127_4502696_3	546414.Deide_13110	3.558e-99	362.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	omcB	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Chlam_OMP6,DUF11
REGS1_k127_4502696_10	243233.MCA2268	9.68e-51	190.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,1RNVM@1236|Gammaproteobacteria,1XE0Y@135618|Methylococcales	135618|Methylococcales	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
REGS1_k127_4502696_12	290397.Adeh_3335	6.22e-41	159.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
REGS1_k127_4502696_5	290397.Adeh_1594	3.36e-93	312.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
REGS1_k127_4502696_8	1396418.BATQ01000136_gene3705	2.455e-61	229.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D. Active site motifs.	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
REGS1_k127_4502696_17	96561.Dole_2317	2.162e-15	77.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,42WYZ@68525|delta/epsilon subdivisions,2WT48@28221|Deltaproteobacteria,2MPCB@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4502696_13	1129794.C427_4423	5.142e-26	122.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Cna_B,DUF285,MucBP,SdrD_B
REGS1_k127_4517664_0	290397.Adeh_0030	8.169e-141	471.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42PCY@68525|delta/epsilon subdivisions,2WJCR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Chemotaxis sensory transducer	-	-	-	ko:K03406,ko:K13487	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal
REGS1_k127_4517664_1	290397.Adeh_0197	1.08e-140	471.0	COG1164@1|root,COG1164@2|Bacteria	2|Bacteria	E	metalloendopeptidase activity	-	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	-
REGS1_k127_4517664_3	290397.Adeh_0196	2.683e-32	129.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
REGS1_k127_4517664_2	404589.Anae109_0212	2.055e-130	424.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,42TM8@68525|delta/epsilon subdivisions,2WQAH@28221|Deltaproteobacteria,2YV6D@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23,5.4.99.24	ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_4517664_4	653733.Selin_2086	1.023e-21	102.0	COG3431@1|root,COG3431@2|Bacteria	2|Bacteria	-	-	pacB	-	-	-	-	-	-	-	-	-	-	-	BLUF,PsiE
REGS1_k127_4522759_0	290397.Adeh_1093	9.79e-194	614.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YV21@29|Myxococcales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
REGS1_k127_4522759_4	290397.Adeh_1094	2.269e-24	106.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
REGS1_k127_4522759_3	290397.Adeh_1095	5.25e-57	205.0	COG0745@1|root,COG0745@2|Bacteria,1RKDZ@1224|Proteobacteria,42SJ2@68525|delta/epsilon subdivisions,2WPC9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	regulator	-	-	-	ko:K07773	ko02020,ko02026,map02020,map02026	M00456	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
REGS1_k127_4522759_2	290397.Adeh_1096	9.563e-132	425.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,42NPN@68525|delta/epsilon subdivisions,2WIY4@28221|Deltaproteobacteria,2YV7Y@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	crtE	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K00795,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_4522759_1	404589.Anae109_1136	2.362e-189	603.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
REGS1_k127_4554149_10	981223.AIED01000017_gene980	7.554e-18	85.0	COG1942@1|root,COG1942@2|Bacteria,1N2V3@1224|Proteobacteria,1SFKB@1236|Gammaproteobacteria,3NN6Y@468|Moraxellaceae	1236|Gammaproteobacteria	S	Tautomerase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Tautomerase_2
REGS1_k127_4554149_5	1121920.AUAU01000024_gene2388	4.729e-76	276.0	COG3005@1|root,COG3043@1|root,COG3005@2|Bacteria,COG3043@2|Bacteria,3Y4BJ@57723|Acidobacteria	57723|Acidobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_4554149_8	290397.Adeh_2924	1.625e-36	144.0	2E6EV@1|root,3312A@2|Bacteria,1N8Q0@1224|Proteobacteria,42WW1@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PgaD-like protein	-	-	-	ko:K11937	ko02026,map02026	-	-	-	ko00000,ko00001	-	-	-	PgaD
REGS1_k127_4554149_2	290397.Adeh_2925	6.239e-222	694.0	COG1215@1|root,COG1215@2|Bacteria,1MXG7@1224|Proteobacteria,42Q7W@68525|delta/epsilon subdivisions,2WKZ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.212	ko:K00752,ko:K11936	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.1.1.10,4.D.1.1.2,4.D.1.1.3,4.D.1.1.4,4.D.1.1.5	GT2	-	Glyco_tranf_2_3,Glycos_transf_2
REGS1_k127_4554149_0	290397.Adeh_2926	5e-324	1002.0	COG0726@1|root,COG1649@1|root,COG0726@2|Bacteria,COG1649@2|Bacteria,1MWR2@1224|Proteobacteria,43AG1@68525|delta/epsilon subdivisions,2WPD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	ko:K11931	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	Polysacc_deac_1
REGS1_k127_4554149_1	404589.Anae109_0989	1.825e-299	933.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
REGS1_k127_4554149_7	290397.Adeh_3961	6.636e-65	242.0	COG3850@1|root,COG3850@2|Bacteria,1N013@1224|Proteobacteria,42Z7D@68525|delta/epsilon subdivisions,2WURU@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
REGS1_k127_4554149_6	290397.Adeh_3962	5.144e-68	247.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,42SD7@68525|delta/epsilon subdivisions,2WPI5@28221|Deltaproteobacteria,2YVK5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
REGS1_k127_4554149_3	290397.Adeh_3933	7.16e-159	510.0	COG0446@1|root,COG0446@2|Bacteria,1QA17@1224|Proteobacteria,42P5E@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	COGs COG1252 NADH dehydrogenase FAD-containing subunit	sqr	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_4554149_9	525904.Tter_0984	2.983e-20	106.0	COG3118@1|root,COG3118@2|Bacteria,2NPNZ@2323|unclassified Bacteria	2|Bacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671,ko:K05838	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	iIT341.HP0824	TPR_16,TPR_19,Thioredoxin
REGS1_k127_4554149_4	1123508.JH636453_gene5800	1.672e-96	356.0	COG3391@1|root,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
REGS1_k127_4584764_2	404589.Anae109_0259	9.985e-288	906.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria,2YTXM@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19,TPR_8,Transglut_core
REGS1_k127_4584764_1	290397.Adeh_0238	2.268e-304	1008.0	COG0457@1|root,COG0457@2|Bacteria,1Q2H1@1224|Proteobacteria,4383J@68525|delta/epsilon subdivisions,2X3DM@28221|Deltaproteobacteria,2YVKC@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19
REGS1_k127_4584764_0	404589.Anae109_3101	0.0	1011.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_4584764_3	404589.Anae109_3103	4.032e-181	580.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
REGS1_k127_4584764_4	404589.Anae109_3104	1.712e-119	406.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2YZM4@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_459736_4	290397.Adeh_2853	2.603e-22	98.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,42PNR@68525|delta/epsilon subdivisions,2WK3I@28221|Deltaproteobacteria,2YV9T@29|Myxococcales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF1730)	yjeS	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
REGS1_k127_459736_0	290397.Adeh_2855	4.349e-152	484.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42PA8@68525|delta/epsilon subdivisions,2X7NH@28221|Deltaproteobacteria,2YU70@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
REGS1_k127_459736_3	404589.Anae109_2936	4.689e-48	179.0	COG4235@1|root,COG4235@2|Bacteria,1RITV@1224|Proteobacteria,43CCM@68525|delta/epsilon subdivisions,2X7NI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
REGS1_k127_459736_1	404589.Anae109_2786	1.812e-92	316.0	COG1329@1|root,COG1329@2|Bacteria	2|Bacteria	K	CarD-like/TRCF domain	carD	GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
REGS1_k127_459736_2	290397.Adeh_2858	2.407e-75	271.0	COG1913@1|root,COG1913@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
REGS1_k127_4612533_0	404589.Anae109_2493	0.0	1043.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2YU4B@29|Myxococcales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
REGS1_k127_4612533_2	404589.Anae109_2543	1.06e-228	734.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2X2UJ@28221|Deltaproteobacteria,2YZ7G@29|Myxococcales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
REGS1_k127_4612533_1	290397.Adeh_1279	8.468e-310	961.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,2YUHH@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
REGS1_k127_4612533_3	404589.Anae109_2486	5.374e-125	455.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2YWX3@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
REGS1_k127_4612533_5	1286631.X805_36370	2.36e-09	69.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,1KM9T@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	glpE	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
REGS1_k127_4612533_4	1499967.BAYZ01000080_gene917	7.45e-47	184.0	COG1032@1|root,COG1032@2|Bacteria,2NQU0@2323|unclassified Bacteria	2|Bacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_46309_11	290397.Adeh_0215	5.17e-11	64.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
REGS1_k127_46309_8	404589.Anae109_0228	4.755e-52	194.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2YVQW@29|Myxococcales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
REGS1_k127_46309_0	290397.Adeh_0212	8.777e-211	662.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,2YU1V@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_46309_1	404589.Anae109_0226	6.654e-185	584.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2YTY2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
REGS1_k127_46309_5	290397.Adeh_4300	1.259e-58	213.0	COG1216@1|root,COG1216@2|Bacteria,1RB30@1224|Proteobacteria	1224|Proteobacteria	U	Pfam Glycosyl transferase family 2	wcaE	GO:0003674,GO:0003824,GO:0016740,GO:0016757	-	ko:K13683	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_1,Glycos_transf_2
REGS1_k127_46309_6	290397.Adeh_0208	4.072e-58	208.0	COG1280@1|root,COG1280@2|Bacteria,1RF18@1224|Proteobacteria,42VB8@68525|delta/epsilon subdivisions,2WS44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
REGS1_k127_46309_4	404589.Anae109_0222	2.913e-83	295.0	COG0847@1|root,COG0847@2|Bacteria,1RDF2@1224|Proteobacteria,435E4@68525|delta/epsilon subdivisions,2WZRN@28221|Deltaproteobacteria,2Z2KX@29|Myxococcales	28221|Deltaproteobacteria	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_46309_7	512565.AMIS_33130	5.023e-53	196.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4DCMH@85008|Micromonosporales	201174|Actinobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
REGS1_k127_46309_3	502025.Hoch_2991	2.629e-108	359.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
REGS1_k127_46309_2	1242864.D187_007378	1.678e-116	383.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria,2YXVU@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
REGS1_k127_46309_12	754027.HMPREF9554_01944	0.000193	55.0	COG0136@1|root,335ZB@2|Bacteria,2J86M@203691|Spirochaetes	203691|Spirochaetes	E	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
REGS1_k127_46309_10	349124.Hhal_1831	7.28e-28	132.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,1RQ8Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_46309_9	391615.ABSJ01000054_gene1467	7.963e-50	183.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria,1JAIZ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
REGS1_k127_4633488_0	290397.Adeh_2599	4.59e-321	991.0	COG0008@1|root,COG0064@1|root,COG0008@2|Bacteria,COG0064@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,2YUA8@29|Myxococcales	28221|Deltaproteobacteria	J	glutaminyl-tRNA	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
REGS1_k127_4633488_3	1242864.D187_004007	3.426e-104	363.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42Q3F@68525|delta/epsilon subdivisions,2WM2F@28221|Deltaproteobacteria,2YUEQ@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_4633488_1	1242864.D187_009616	3.065e-129	463.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
REGS1_k127_4633488_5	706587.Desti_1550	8.375e-63	227.0	COG0491@1|root,COG0491@2|Bacteria,1NCIF@1224|Proteobacteria	1224|Proteobacteria	S	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_4633488_4	1121918.ARWE01000001_gene3108	5.391e-84	294.0	COG0580@1|root,COG0580@2|Bacteria,1MZ47@1224|Proteobacteria	1224|Proteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
REGS1_k127_4633488_2	861299.J421_1868	7.446e-126	409.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
REGS1_k127_4643826_1	194439.CT0498	1.691e-157	541.0	COG0004@1|root,COG0004@2|Bacteria,1FDC2@1090|Chlorobi	2|Bacteria	P	PFAM Rh family protein ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
REGS1_k127_4643826_2	290397.Adeh_1490	1.539e-75	262.0	2EFEP@1|root,3397H@2|Bacteria,1NIUR@1224|Proteobacteria,42XV7@68525|delta/epsilon subdivisions,2WSZK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4643826_5	290397.Adeh_4248	2.448e-53	189.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2YVH0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
REGS1_k127_4643826_0	290397.Adeh_3668	2.708e-169	544.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,42UIK@68525|delta/epsilon subdivisions,2X5D2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
REGS1_k127_4643826_4	404589.Anae109_4397	1.881e-53	194.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2YVH0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
REGS1_k127_4643826_3	290397.Adeh_1491	5.677e-69	238.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2Z2XY@29|Myxococcales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
REGS1_k127_4643922_1	404589.Anae109_3703	2.312e-64	230.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YTYT@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
REGS1_k127_4643922_0	404589.Anae109_3702	4.184e-88	311.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,42RIT@68525|delta/epsilon subdivisions,2WP64@28221|Deltaproteobacteria,2Z1V2@29|Myxococcales	28221|Deltaproteobacteria	O	Glycoprotease family	yeaZ	-	2.3.1.234	ko:K01409,ko:K14742	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_4643922_2	580332.Slit_2306	2.988e-21	103.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
REGS1_k127_4645675_3	290397.Adeh_4270	1.952e-262	838.0	COG1196@1|root,COG1196@2|Bacteria,1QX9X@1224|Proteobacteria,43018@68525|delta/epsilon subdivisions,2WVD9@28221|Deltaproteobacteria,2YW2N@29|Myxococcales	28221|Deltaproteobacteria	D	Domain of unknown function (DUF4175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
REGS1_k127_4645675_8	404589.Anae109_4423	2.114e-142	500.0	COG0308@1|root,COG4783@1|root,COG0308@2|Bacteria,COG4783@2|Bacteria,1RBHC@1224|Proteobacteria,42QWW@68525|delta/epsilon subdivisions,2WMP2@28221|Deltaproteobacteria,2YUU2@29|Myxococcales	28221|Deltaproteobacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
REGS1_k127_4645675_7	290397.Adeh_4268	3.644e-178	562.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YWPA@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase associated with various cellular activities	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_4645675_11	404589.Anae109_4421	4.912e-136	455.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria,43B77@68525|delta/epsilon subdivisions,2X6KN@28221|Deltaproteobacteria,2Z3BN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_4645675_2	290397.Adeh_4265	2.509e-265	852.0	COG2304@1|root,COG2304@2|Bacteria,1NX8F@1224|Proteobacteria,430QD@68525|delta/epsilon subdivisions,2WVNR@28221|Deltaproteobacteria,2YW4W@29|Myxococcales	28221|Deltaproteobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
REGS1_k127_4645675_0	443143.GM18_2394	0.0	1702.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MI4@68525|delta/epsilon subdivisions,2WKB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
REGS1_k127_4645675_13	316067.Geob_1351	3.571e-121	393.0	COG0437@1|root,COG0437@2|Bacteria,1PF80@1224|Proteobacteria,439WY@68525|delta/epsilon subdivisions,2X26N@28221|Deltaproteobacteria,43VKJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
REGS1_k127_4645675_6	404589.Anae109_4419	2.574e-179	567.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2WK5Q@28221|Deltaproteobacteria,2Z31B@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
REGS1_k127_4645675_4	404589.Anae109_4417	1.032e-200	633.0	COG0745@1|root,COG0745@2|Bacteria	404589.Anae109_4417|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4645675_5	290397.Adeh_4261	8.679e-184	606.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42MSJ@68525|delta/epsilon subdivisions,2WKHJ@28221|Deltaproteobacteria,2YW9B@29|Myxococcales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_4645675_9	290397.Adeh_4260	4.401e-142	456.0	COG0559@1|root,COG0559@2|Bacteria,1MU25@1224|Proteobacteria,42NUE@68525|delta/epsilon subdivisions,2WMSB@28221|Deltaproteobacteria,2Z33U@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_4645675_12	290397.Adeh_4259	3.693e-128	448.0	COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,42M19@68525|delta/epsilon subdivisions,2WIYH@28221|Deltaproteobacteria,2YUXC@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_4645675_10	290397.Adeh_4258	5.35e-138	443.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NMG@68525|delta/epsilon subdivisions,2WJIS@28221|Deltaproteobacteria,2YWX6@29|Myxococcales	28221|Deltaproteobacteria	E	amino acid ABC transporter, ATP-binding protein	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_4645675_15	404589.Anae109_4412	4.305e-116	378.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2YV0S@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
REGS1_k127_4645675_1	290397.Adeh_4252	1.894e-300	923.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2YUPP@29|Myxococcales	28221|Deltaproteobacteria	H	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
REGS1_k127_4645675_14	404380.Gbem_2805	3.651e-118	397.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_4645675_16	404589.Anae109_4398	1.193e-87	293.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
REGS1_k127_4649103_0	290397.Adeh_0766	1.64e-141	451.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42PGQ@68525|delta/epsilon subdivisions,2WMJB@28221|Deltaproteobacteria,2YUUP@29|Myxococcales	28221|Deltaproteobacteria	C	Cysteine-rich domain	glpC	-	1.1.5.3	ko:K00113	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	CCG,Fer4_17,Fer4_8
REGS1_k127_4649103_3	404589.Anae109_0813	1.109e-70	256.0	COG0247@1|root,COG0247@2|Bacteria,1RF02@1224|Proteobacteria,43DRN@68525|delta/epsilon subdivisions,2WYQA@28221|Deltaproteobacteria,2Z0CV@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
REGS1_k127_4649103_2	290397.Adeh_0768	6.599e-73	252.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	dnaQ3	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
REGS1_k127_4649103_1	290397.Adeh_0769	5.993e-79	271.0	COG2200@1|root,COG2200@2|Bacteria,1RA10@1224|Proteobacteria,42W8U@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL
REGS1_k127_4700539_0	1120973.AQXL01000135_gene1426	3.239e-141	466.0	COG3261@1|root,COG3261@2|Bacteria,1VZGX@1239|Firmicutes,4HTTH@91061|Bacilli	91061|Bacilli	C	Nickel-dependent hydrogenase	-	-	-	ko:K15830	-	-	-	-	ko00000	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
REGS1_k127_4700539_2	351160.RCIX2384	4.755e-121	414.0	COG0651@1|root,arCOG01537@2157|Archaea,2XWXC@28890|Euryarchaeota,2NADW@224756|Methanomicrobia	224756|Methanomicrobia	C	plastoquinone (Complex I)	-	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
REGS1_k127_4700539_7	330214.NIDE4263	2.122e-26	125.0	COG4237@1|root,COG4237@2|Bacteria,3J166@40117|Nitrospirae	40117|Nitrospirae	C	Hydrogenase 4 membrane	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
REGS1_k127_4700539_6	330214.NIDE4264	4.15e-62	244.0	COG0650@1|root,COG0650@2|Bacteria,3J0RR@40117|Nitrospirae	40117|Nitrospirae	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
REGS1_k127_4700539_1	452637.Oter_2460	1.226e-133	456.0	COG0651@1|root,COG0651@2|Bacteria,46U4G@74201|Verrucomicrobia,3K7M3@414999|Opitutae	74201|Verrucomicrobia	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
REGS1_k127_4700539_3	861299.J421_2962	1.754e-96	348.0	COG4191@1|root,COG4191@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
REGS1_k127_4700539_4	404589.Anae109_2900	5.39e-88	302.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
REGS1_k127_4713503_3	290397.Adeh_1274	1.073e-23	101.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_4713503_4	945713.IALB_0271	3.628e-21	95.0	COG1036@1|root,COG1036@2|Bacteria	2|Bacteria	C	dihydromethanopterin reductase activity	rnfB	-	1.2.7.3	ko:K00176,ko:K03616	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	FeS,Fer4,Fer4_7
REGS1_k127_4713503_0	945713.IALB_0272	1.246e-146	472.0	COG0674@1|root,COG0674@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
REGS1_k127_4713503_1	945713.IALB_0273	6.793e-105	346.0	COG1013@1|root,COG1013@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	vorB	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00175,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
REGS1_k127_4713503_2	945713.IALB_0274	4.176e-63	246.0	COG1014@1|root,COG1014@2|Bacteria	2|Bacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	porG	-	1.2.7.3,1.2.7.7	ko:K00177,ko:K00187	ko00020,ko00280,ko00720,ko01100,ko01120,ko01200,map00020,map00280,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197,R07160,R08566,R08567	RC00004,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
REGS1_k127_4730033_8	416348.Hlac_0508	5.693e-20	101.0	COG0574@1|root,arCOG01114@2157|Archaea,2XVSY@28890|Euryarchaeota,23UK4@183963|Halobacteria	183963|Halobacteria	G	COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
REGS1_k127_4730033_7	13689.BV96_02896	4.69e-21	101.0	COG1309@1|root,COG1309@2|Bacteria,1ND9Y@1224|Proteobacteria,2UHID@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_4730033_4	502025.Hoch_6206	3.498e-72	268.0	COG0661@1|root,COG0661@2|Bacteria,1NXB8@1224|Proteobacteria,43B1X@68525|delta/epsilon subdivisions,2X6FZ@28221|Deltaproteobacteria,2Z3AW@29|Myxococcales	28221|Deltaproteobacteria	C	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
REGS1_k127_4730033_6	1125863.JAFN01000001_gene3184	3.635e-21	110.0	2BS95@1|root,32MAT@2|Bacteria,1RHA2@1224|Proteobacteria,42ZVY@68525|delta/epsilon subdivisions,2WV4S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4730033_1	215803.DB30_8931	8.2e-100	331.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,4345E@68525|delta/epsilon subdivisions,2X1ZZ@28221|Deltaproteobacteria,2Z07W@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_4730033_2	215803.DB30_8930	1.645e-96	341.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42NUK@68525|delta/epsilon subdivisions,2WKP4@28221|Deltaproteobacteria,2Z0M7@29|Myxococcales	28221|Deltaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_4730033_5	215803.DB30_8929	7.293e-63	231.0	COG2834@1|root,COG2834@2|Bacteria,1RE9C@1224|Proteobacteria,42U1U@68525|delta/epsilon subdivisions,2WQTI@28221|Deltaproteobacteria,2Z0VA@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
REGS1_k127_4730033_3	215803.DB30_8928	1.103e-91	331.0	COG4591@1|root,COG4591@2|Bacteria,1NT73@1224|Proteobacteria,439WS@68525|delta/epsilon subdivisions,2X9R4@28221|Deltaproteobacteria,2Z0AM@29|Myxococcales	28221|Deltaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
REGS1_k127_4730033_0	215803.DB30_8928	2.986e-104	354.0	COG4591@1|root,COG4591@2|Bacteria,1NT73@1224|Proteobacteria,439WS@68525|delta/epsilon subdivisions,2X9R4@28221|Deltaproteobacteria,2Z0AM@29|Myxococcales	28221|Deltaproteobacteria	M	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
REGS1_k127_4736534_21	404589.Anae109_4110	7.079e-36	137.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,43BMM@68525|delta/epsilon subdivisions,2X64M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.8.5.5	ko:K08352	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko01000,ko02000	5.A.3.5	-	-	Molybdopterin,Molydop_binding
REGS1_k127_4736534_16	404589.Anae109_4109	7.631e-84	284.0	COG0437@1|root,COG0437@2|Bacteria,1NBNQ@1224|Proteobacteria,43AK8@68525|delta/epsilon subdivisions,2X64K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11
REGS1_k127_4736534_20	404589.Anae109_4108	1.771e-45	170.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,42URY@68525|delta/epsilon subdivisions,2WQYF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_4736534_17	404589.Anae109_4107	1.86e-81	293.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,42QRV@68525|delta/epsilon subdivisions,2WMUE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_4736534_10	404589.Anae109_4106	3.528e-115	379.0	COG3301@1|root,COG3301@2|Bacteria,1MXQ9@1224|Proteobacteria,42NE8@68525|delta/epsilon subdivisions,2WSJ7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
REGS1_k127_4736534_15	404589.Anae109_3016	4.556e-86	308.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
REGS1_k127_4736534_22	1132836.RCCGE510_00330	2.828e-19	98.0	2DYXD@1|root,34BK9@2|Bacteria,1QZWY@1224|Proteobacteria,2TYGD@28211|Alphaproteobacteria,4BDZC@82115|Rhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4736534_13	903818.KI912269_gene528	5.691e-95	338.0	COG4191@1|root,COG4191@2|Bacteria,3Y2IQ@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
REGS1_k127_4736534_3	290397.Adeh_2625	5.242e-177	563.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
REGS1_k127_4736534_12	290397.Adeh_2624	4.265e-112	371.0	COG1216@1|root,COG1216@2|Bacteria,1QX3U@1224|Proteobacteria,42RP8@68525|delta/epsilon subdivisions,2WNF5@28221|Deltaproteobacteria,2Z30X@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
REGS1_k127_4736534_19	290397.Adeh_2623	2.669e-63	223.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,42TIP@68525|delta/epsilon subdivisions,2WQA8@28221|Deltaproteobacteria,2YZB0@29|Myxococcales	28221|Deltaproteobacteria	U	UPF0056 inner membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
REGS1_k127_4736534_0	290397.Adeh_2618	0.0	1120.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,2YUGE@29|Myxococcales	28221|Deltaproteobacteria	J	Elongation factor G, domain IV	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_4736534_1	290397.Adeh_2617	5.445e-263	822.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_4736534_11	404589.Anae109_2583	3.038e-113	376.0	COG0613@1|root,COG0613@2|Bacteria,1Q692@1224|Proteobacteria,432NB@68525|delta/epsilon subdivisions,2WXVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4736534_2	290397.Adeh_2615	5.427e-207	650.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WJ6Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Three-deoxy-D-manno-octulosonic-acid transferase	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
REGS1_k127_4736534_6	290397.Adeh_2614	2.49e-145	501.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42UES@68525|delta/epsilon subdivisions,2WQD1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
REGS1_k127_4736534_8	404589.Anae109_2580	1.871e-126	430.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
REGS1_k127_4736534_7	290397.Adeh_2612	2.105e-134	433.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	msbB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
REGS1_k127_4736534_5	290397.Adeh_2611	1.763e-151	484.0	COG2870@1|root,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2WIKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_0922	CTP_transf_like,PfkB
REGS1_k127_4736534_18	404589.Anae109_2577	4.531e-78	264.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,42SGQ@68525|delta/epsilon subdivisions,2WPTP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	rfaE	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
REGS1_k127_4736534_4	290397.Adeh_2609	6.084e-161	514.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K00754	-	-	-	-	ko00000,ko01000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_2,Glyco_transf_4,Glycos_transf_1
REGS1_k127_4736534_23	290397.Adeh_2608	9.808e-15	88.0	COG2835@1|root,COG2835@2|Bacteria,1Q1BG@1224|Proteobacteria,42WTN@68525|delta/epsilon subdivisions,2WSI9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0434 family	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
REGS1_k127_4736534_9	404589.Anae109_2574	3.323e-119	389.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2YVIN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
REGS1_k127_4736534_14	290397.Adeh_2606	4.544e-89	302.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,42R4H@68525|delta/epsilon subdivisions,2WNAD@28221|Deltaproteobacteria,2YV51@29|Myxococcales	28221|Deltaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
REGS1_k127_4736534_24	445335.CBN_A0062	6.6e-09	64.0	2ERMT@1|root,33J79@2|Bacteria,1VKZE@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4737668_6	338966.Ppro_2729	0.0003803	51.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42T1Z@68525|delta/epsilon subdivisions,2WPPA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_2,PHY
REGS1_k127_4737668_1	404589.Anae109_0633	2.387e-155	499.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,2YTTI@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145,ko:K05829	ko00220,ko00300,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01130,map01210,map01230	M00028,M00031,M00763,M00845	R03443,R09777,R10931	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_4737668_0	404589.Anae109_0632	0.0	1150.0	COG0548@1|root,COG1364@1|root,COG0548@2|Bacteria,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,2YV2H@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	-	-	2.3.1.1,2.3.1.35,2.7.2.8	ko:K00620,ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ArgJ
REGS1_k127_4737668_5	290397.Adeh_0586	1.741e-44	186.0	COG1438@1|root,COG1438@2|Bacteria,1N2AF@1224|Proteobacteria,435GT@68525|delta/epsilon subdivisions,2WZUC@28221|Deltaproteobacteria,2Z2RY@29|Myxococcales	28221|Deltaproteobacteria	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
REGS1_k127_4737668_4	404589.Anae109_0340	1.633e-55	203.0	COG0484@1|root,COG0484@2|Bacteria,1N40E@1224|Proteobacteria,42UFJ@68525|delta/epsilon subdivisions,2WQAY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4737668_2	404589.Anae109_0629	8.263e-82	279.0	COG1232@1|root,COG1232@2|Bacteria,1R5SZ@1224|Proteobacteria,42YX0@68525|delta/epsilon subdivisions,2WTXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Flavin containing amine oxidoreductase	-	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
REGS1_k127_4756499_8	1144275.COCOR_03350	1.513e-11	71.0	COG4254@1|root,COG4254@2|Bacteria,1QVB5@1224|Proteobacteria,42XP1@68525|delta/epsilon subdivisions,2X71D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
REGS1_k127_4756499_10	1144275.COCOR_03351	2.018e-07	63.0	COG0515@1|root,COG0515@2|Bacteria	1144275.COCOR_03351|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
REGS1_k127_4756499_4	290397.Adeh_0954	1.744e-73	253.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2Z1ZP@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
REGS1_k127_4756499_1	290397.Adeh_0955	7.146e-152	486.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WJ4I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535,ko:K13599	ko00540,ko01100,ko02020,map00540,map01100,map02020	M00060,M00498	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005,ko02022	-	-	-	LpxC
REGS1_k127_4756499_0	290397.Adeh_0965	2.214e-216	698.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MHC@68525|delta/epsilon subdivisions,2WINZ@28221|Deltaproteobacteria,2YW0C@29|Myxococcales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro,Acetyltransf_1
REGS1_k127_4756499_2	471855.Shel_16980	9.933e-141	484.0	COG4676@1|root,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF2135,Plug,VIT,VWA_3
REGS1_k127_4756499_7	290512.Paes_0960	6.993e-14	79.0	COG4194@1|root,COG4194@2|Bacteria,1FF6D@1090|Chlorobi	1090|Chlorobi	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
REGS1_k127_4756499_3	192952.MM_1582	2.449e-76	261.0	COG0655@1|root,arCOG02573@2157|Archaea,2XWPJ@28890|Euryarchaeota,2NAHI@224756|Methanomicrobia	224756|Methanomicrobia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_4761663_9	290397.Adeh_3987	7.935e-23	99.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
REGS1_k127_4761663_5	640081.Dsui_0984	2.356e-113	386.0	COG0119@1|root,COG0119@2|Bacteria,1MUMX@1224|Proteobacteria,2VIUW@28216|Betaproteobacteria,2KUNG@206389|Rhodocyclales	206389|Rhodocyclales	E	HMGL-like	hmgL	-	4.1.3.4	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	M00036,M00088	R01360,R08090	RC00502,RC00503,RC01118,RC01946	ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
REGS1_k127_4761663_6	640081.Dsui_0981	2.364e-78	273.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,2VI5G@28216|Betaproteobacteria,2KU7S@206389|Rhodocyclales	206389|Rhodocyclales	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.18	ko:K13766	ko00280,ko01100,map00280,map01100	M00036	R02085	RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
REGS1_k127_4761663_0	1304883.KI912532_gene719	2.725e-272	844.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,2VI77@28216|Betaproteobacteria,2KVX8@206389|Rhodocyclales	206389|Rhodocyclales	I	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)	-	-	6.4.1.4	ko:K01969	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
REGS1_k127_4761663_1	290397.Adeh_3088	7.974e-197	634.0	COG5557@1|root,COG5557@2|Bacteria,1R7R0@1224|Proteobacteria,42P0Z@68525|delta/epsilon subdivisions,2X7KR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
REGS1_k127_4761663_4	290397.Adeh_3087	1.599e-133	433.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,2Z16M@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
REGS1_k127_4761663_7	404589.Anae109_3087	1.077e-62	224.0	2EE9W@1|root,3384B@2|Bacteria,1NCE1@1224|Proteobacteria,42VUH@68525|delta/epsilon subdivisions,2WSA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	cbcS	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
REGS1_k127_4761663_3	404589.Anae109_3084	3.231e-148	488.0	2C6TZ@1|root,32RHS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4761663_2	404589.Anae109_0997	3.067e-185	582.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2YUGW@29|Myxococcales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
REGS1_k127_4761663_8	1123401.JHYQ01000047_gene166	2.787e-46	175.0	COG1373@1|root,COG1373@2|Bacteria,1R7UA@1224|Proteobacteria,1SK42@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
REGS1_k127_4762820_3	290397.Adeh_1240	1.235e-70	243.0	COG1803@1|root,COG1803@2|Bacteria,1RD3D@1224|Proteobacteria,42SPC@68525|delta/epsilon subdivisions,2WP55@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	TIGRFAM Methylglyoxal synthase	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
REGS1_k127_4762820_1	1336208.JADY01000020_gene3442	6.383e-177	568.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2U357@28211|Alphaproteobacteria,2JZFJ@204441|Rhodospirillales	204441|Rhodospirillales	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	-	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
REGS1_k127_4762820_0	404589.Anae109_2758	7.155e-200	667.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome c oxidase, subunit I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
REGS1_k127_4762820_2	404589.Anae109_2759	3.355e-92	309.0	COG2010@1|root,COG2010@2|Bacteria,1RDSI@1224|Proteobacteria,42WEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	cytochrome c	norC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02305	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002	3.D.4.10	-	-	Cytochrom_C
REGS1_k127_4762820_5	768710.DesyoDRAFT_2029	1.817e-47	196.0	COG1146@1|root,COG1146@2|Bacteria,1UZSY@1239|Firmicutes,25EKY@186801|Clostridia,263BD@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_4762820_4	459349.CLOAM1631	3.039e-51	201.0	COG0167@1|root,COG0493@1|root,COG1148@1|root,COG0167@2|Bacteria,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	pds	-	1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9	ko:K00207,ko:K00219,ko:K00317,ko:K02293,ko:K10797,ko:K12527,ko:K17723	ko00240,ko00360,ko00410,ko00450,ko00680,ko00770,ko00906,ko00983,ko01100,ko01110,ko01120,ko01200,map00240,map00360,map00410,map00450,map00680,map00770,map00906,map00983,map01100,map01110,map01120,map01200	M00046,M00097	R00977,R00978,R01414,R01415,R01588,R02252,R02511,R04786,R04787,R07229,R07510,R08226,R09652,R09653,R09654,R11026	RC00072,RC00123,RC00185,RC00556,RC00557,RC00669,RC00732,RC01214,RC01958,RC02245,RC02420,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4,Fer4_4,Pyr_redox_2
REGS1_k127_4820463_2	552811.Dehly_0236	4.052e-08	54.0	COG0031@1|root,COG0031@2|Bacteria,2G698@200795|Chloroflexi,34DQK@301297|Dehalococcoidia	200795|Chloroflexi	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738,ko:K12339	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03132,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_4820463_0	404589.Anae109_1771	1.241e-92	334.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WUVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
REGS1_k127_4836302_0	404589.Anae109_3885	6.144e-249	775.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2YTUP@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_4836302_2	404589.Anae109_3886	8.016e-111	387.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2WN8T@28221|Deltaproteobacteria,2Z308@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
REGS1_k127_4836302_1	290397.Adeh_3774	3.823e-147	472.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
REGS1_k127_4836302_3	247490.KSU1_B0229	9e-31	130.0	2ECCV@1|root,336B4@2|Bacteria,2J3S9@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4894888_1	404589.Anae109_0171	3.712e-196	626.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria,42MKF@68525|delta/epsilon subdivisions,2X6XB@28221|Deltaproteobacteria,2Z3DG@29|Myxococcales	28221|Deltaproteobacteria	K	Domain of unknown function (DUF814)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
REGS1_k127_4894888_2	404589.Anae109_0172	8.299e-105	347.0	COG1451@1|root,COG1451@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF45	CP_0175	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45,SprT-like
REGS1_k127_4894888_3	1278073.MYSTI_07075	5.566e-94	332.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42MB2@68525|delta/epsilon subdivisions,2WJAF@28221|Deltaproteobacteria,2YVJQ@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277,ko:K07278	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
REGS1_k127_4894888_0	290397.Adeh_0165	0.0	1067.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,42PSZ@68525|delta/epsilon subdivisions,2WMBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
REGS1_k127_4894888_4	290397.Adeh_0167	7.939e-67	240.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
REGS1_k127_4896386_2	404589.Anae109_2110	5.397e-104	342.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,42R54@68525|delta/epsilon subdivisions,2WMNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM ThiJ PfpI domain protein	elbB	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
REGS1_k127_4896386_1	290397.Adeh_1694	5.709e-181	595.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2Z0ST@29|Myxococcales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
REGS1_k127_4896386_0	290397.Adeh_1692	0.0	1082.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2YU3A@29|Myxococcales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
REGS1_k127_4923186_3	404589.Anae109_4028	1.365e-75	260.0	COG3064@1|root,COG3064@2|Bacteria,1R7D3@1224|Proteobacteria,42Y44@68525|delta/epsilon subdivisions,2WT88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4923186_1	404589.Anae109_2474	6.754e-150	479.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2YWFP@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ C terminal domain	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
REGS1_k127_4923186_2	404589.Anae109_2475	3.145e-88	304.0	COG1413@1|root,COG1413@2|Bacteria,1PC2V@1224|Proteobacteria,4387S@68525|delta/epsilon subdivisions,2X3HJ@28221|Deltaproteobacteria,2YW4Z@29|Myxococcales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
REGS1_k127_4923186_0	290397.Adeh_1289	3.285e-271	869.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2Z2SY@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_4935185_7	1463857.JOFZ01000005_gene3241	1.87e-09	66.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
REGS1_k127_4935185_5	1379270.AUXF01000002_gene1781	1e-18	93.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	-	-	-	-	-	-	-	-	-	PBP_like_2
REGS1_k127_4935185_3	1499967.BAYZ01000105_gene3477	4.988e-54	206.0	28UH1@1|root,2ZGMU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
REGS1_k127_4935185_0	290397.Adeh_3704	4.085e-131	439.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,439XE@68525|delta/epsilon subdivisions,2X4RA@28221|Deltaproteobacteria,2YZFJ@29|Myxococcales	28221|Deltaproteobacteria	NT	Four helix bundle sensory module for signal transduction	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
REGS1_k127_4935185_2	1121920.AUAU01000014_gene2803	2.382e-106	359.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_4935185_1	404589.Anae109_4200	3.376e-121	395.0	COG0330@1|root,COG0330@2|Bacteria,1N5JY@1224|Proteobacteria,42MNX@68525|delta/epsilon subdivisions,2WK2W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_4935185_4	404589.Anae109_4026	9.298e-54	190.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria,2YV3K@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_4935572_2	290397.Adeh_1558	1.549e-94	315.0	COG0457@1|root,COG0457@2|Bacteria,1QYG1@1224|Proteobacteria,43CC5@68525|delta/epsilon subdivisions,2X7N0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4935572_4	290397.Adeh_1557	1.563e-22	104.0	COG0695@1|root,COG0695@2|Bacteria,1P8SJ@1224|Proteobacteria,42XTX@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	Glutaredoxin	-	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
REGS1_k127_4935572_1	404589.Anae109_2257	6.405e-117	391.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WMXZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
REGS1_k127_4935572_0	404589.Anae109_2260	9.827e-154	503.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,43AKR@68525|delta/epsilon subdivisions,2X60Q@28221|Deltaproteobacteria,2Z382@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
REGS1_k127_4935572_3	290397.Adeh_1552	8.132e-81	270.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,2YV1R@29|Myxococcales	28221|Deltaproteobacteria	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
REGS1_k127_4963416_3	290397.Adeh_0308	2.041e-08	57.0	COG0477@1|root,COG2814@2|Bacteria,1MW6T@1224|Proteobacteria,42U81@68525|delta/epsilon subdivisions	1224|Proteobacteria	EGP	Uncharacterised MFS-type transporter YbfB	-	-	-	-	-	-	-	-	-	-	-	-	MFS_4
REGS1_k127_4963416_1	1198452.Jab_2c30060	1.04e-72	275.0	COG3391@1|root,COG3391@2|Bacteria,1NT8H@1224|Proteobacteria,2W119@28216|Betaproteobacteria	28216|Betaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4963416_0	404589.Anae109_3253	1.068e-89	302.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,42ZJH@68525|delta/epsilon subdivisions,2WV0V@28221|Deltaproteobacteria,2Z319@29|Myxococcales	28221|Deltaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
REGS1_k127_4963416_2	404589.Anae109_3251	5.413e-46	166.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,42SE7@68525|delta/epsilon subdivisions,2WPK7@28221|Deltaproteobacteria,2YVBX@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_5008270_1	1242864.D187_000267	4.68e-129	428.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_5008270_2	290397.Adeh_4213	5.535e-95	329.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	GAF_2,HATPase_c,HATPase_c_2,HWE_HK,HisKA,PAS_3,Response_reg
REGS1_k127_5008270_0	1123508.JH636446_gene6369	1.867e-132	467.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_5008270_3	290397.Adeh_2199	4.621e-29	122.0	COG1028@1|root,COG1028@2|Bacteria,1R4BM@1224|Proteobacteria,42PS2@68525|delta/epsilon subdivisions,2WJJK@28221|Deltaproteobacteria,2YU82@29|Myxococcales	28221|Deltaproteobacteria	IQ	short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
REGS1_k127_5052450_3	290397.Adeh_2933	4.45e-55	196.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria,2Z30R@29|Myxococcales	28221|Deltaproteobacteria	C	fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_5052450_1	290397.Adeh_2934	4.655e-78	267.0	2CAZH@1|root,2Z7RU@2|Bacteria,1RBDC@1224|Proteobacteria,42SC7@68525|delta/epsilon subdivisions,2WP8S@28221|Deltaproteobacteria,2Z0M1@29|Myxococcales	28221|Deltaproteobacteria	C	fumarate reductase) cytochrome b subunit	frdC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
REGS1_k127_5052450_0	290397.Adeh_0434	1.546e-108	365.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,42PFX@68525|delta/epsilon subdivisions,2WJS3@28221|Deltaproteobacteria,2YXB6@29|Myxococcales	28221|Deltaproteobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
REGS1_k127_5052450_2	290397.Adeh_0433	1.987e-66	258.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria,2YWNV@29|Myxococcales	28221|Deltaproteobacteria	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
REGS1_k127_508477_7	404589.Anae109_3768	7.321e-34	136.0	COG0457@1|root,COG0457@2|Bacteria,1R7XY@1224|Proteobacteria,42NFC@68525|delta/epsilon subdivisions,2WMA4@28221|Deltaproteobacteria,2Z18K@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
REGS1_k127_508477_1	290397.Adeh_3643	3.107e-168	542.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,2YUZJ@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
REGS1_k127_508477_5	290397.Adeh_3644	3.229e-56	211.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	ko:K21009	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	GAF,GAF_2,HATPase_c_2,HisKA,PAS,PAS_4,PAS_8,Response_reg
REGS1_k127_508477_0	404589.Anae109_3770	3.522e-186	598.0	COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2WMAP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA,TSP_3,VWA
REGS1_k127_508477_4	404589.Anae109_3789	2.623e-79	282.0	COG0500@1|root,COG2226@2|Bacteria,1NNI3@1224|Proteobacteria,4321D@68525|delta/epsilon subdivisions,2WX0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_508477_2	290397.Adeh_3691	1.248e-113	371.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	pph1	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
REGS1_k127_508477_6	1278073.MYSTI_02343	1.485e-40	157.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,2YZSU@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_508477_3	290397.Adeh_3689	1.756e-88	298.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,DnaJ
REGS1_k127_5121687_1	1120988.AXWV01000043_gene942	2.486e-08	56.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,1S3UP@1236|Gammaproteobacteria,1Y495@135624|Aeromonadales	135624|Aeromonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_5121687_0	1232410.KI421413_gene960	9.728e-55	211.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,43RYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	SurA N-terminal domain	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_5176249_8	96561.Dole_3189	2.51e-41	171.0	COG2519@1|root,COG2519@2|Bacteria	2|Bacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	-	ko:K13613	-	-	-	-	ko00000,ko01004,ko01008	-	-	-	Methyltransf_21
REGS1_k127_5176249_10	497964.CfE428DRAFT_2492	4.645e-19	102.0	COG0501@1|root,COG0501@2|Bacteria	2|Bacteria	O	metalloendopeptidase activity	-	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
REGS1_k127_5176249_9	215803.DB30_1378	1.167e-39	158.0	COG0597@1|root,COG0597@2|Bacteria,1N9NS@1224|Proteobacteria,432Z6@68525|delta/epsilon subdivisions,2WXKU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Signal peptidase (SPase) II	-	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
REGS1_k127_5176249_3	290397.Adeh_3428	3.872e-138	449.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria,2YUPR@29|Myxococcales	28221|Deltaproteobacteria	E	Amino-transferase class IV	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
REGS1_k127_5176249_5	290397.Adeh_3431	4.072e-55	196.0	2AGM5@1|root,316UC@2|Bacteria,1PY0S@1224|Proteobacteria,43509@68525|delta/epsilon subdivisions,2WZB6@28221|Deltaproteobacteria,2Z1RE@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5176249_4	404589.Anae109_0531	3.376e-60	218.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,42RSE@68525|delta/epsilon subdivisions,2WP0K@28221|Deltaproteobacteria,2Z0A0@29|Myxococcales	28221|Deltaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
REGS1_k127_5176249_7	404589.Anae109_4261	2.25e-41	156.0	COG4633@1|root,COG4633@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1,DsbD_2,HMA
REGS1_k127_5176249_2	404589.Anae109_4262	7.999e-160	517.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WNCM@28221|Deltaproteobacteria,2Z20A@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_5176249_1	404589.Anae109_4263	1.241e-207	680.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2YZUC@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
REGS1_k127_5176249_0	404589.Anae109_4264	0.0	1887.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
REGS1_k127_5176249_6	404589.Anae109_3494	8.271e-47	174.0	COG1832@1|root,COG1832@2|Bacteria,1NJW8@1224|Proteobacteria,42WY1@68525|delta/epsilon subdivisions,2WT3S@28221|Deltaproteobacteria,2Z10K@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_2
REGS1_k127_5176297_5	404589.Anae109_1020	5.688e-72	248.0	COG1309@1|root,COG1309@2|Bacteria,1R6RX@1224|Proteobacteria,42T50@68525|delta/epsilon subdivisions,2WPVV@28221|Deltaproteobacteria,2YUY1@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
REGS1_k127_5176297_3	290397.Adeh_0956	3.615e-94	321.0	COG3250@1|root,COG3250@2|Bacteria,1R87I@1224|Proteobacteria,42TSR@68525|delta/epsilon subdivisions,2WQI3@28221|Deltaproteobacteria,2YUZ5@29|Myxococcales	28221|Deltaproteobacteria	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
REGS1_k127_5176297_1	404589.Anae109_0117	6.219e-201	628.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
REGS1_k127_5176297_0	290397.Adeh_0114	4.977e-238	755.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1MWGR@1224|Proteobacteria,432ME@68525|delta/epsilon subdivisions,2WYJH@28221|Deltaproteobacteria,2Z1S7@29|Myxococcales	28221|Deltaproteobacteria	EU	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
REGS1_k127_5176297_2	290397.Adeh_0115	3.568e-187	618.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_5176297_6	290397.Adeh_4218	1.343e-48	201.0	COG0671@1|root,COG0671@2|Bacteria,1RIRR@1224|Proteobacteria,42X79@68525|delta/epsilon subdivisions,2WXA0@28221|Deltaproteobacteria,2YVD9@29|Myxococcales	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_5176297_4	761193.Runsl_2497	3.865e-78	268.0	COG0288@1|root,COG0288@2|Bacteria,4NEJT@976|Bacteroidetes,47PCQ@768503|Cytophagia	976|Bacteroidetes	P	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
REGS1_k127_5176297_7	1479237.JMLY01000001_gene2758	7.35e-44	167.0	COG0778@1|root,COG0778@2|Bacteria,1RBXY@1224|Proteobacteria,1RZZ2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_5208952_3	290397.Adeh_0879	2.752e-59	209.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LCCL,OmpA
REGS1_k127_5208952_1	404589.Anae109_1112	7.609e-164	533.0	COG4775@1|root,COG4775@2|Bacteria,1PBXZ@1224|Proteobacteria,433TZ@68525|delta/epsilon subdivisions,2X3G3@28221|Deltaproteobacteria,2YVY6@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
REGS1_k127_5208952_0	290397.Adeh_1071	2.052e-179	590.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YV0J@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
REGS1_k127_5208952_2	404589.Anae109_1109	5.227e-101	361.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria,42KZX@68525|delta/epsilon subdivisions,2WM2N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
REGS1_k127_5208952_5	404589.Anae109_1105	2.283e-05	49.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_5209385_3	1198452.Jab_1c16940	5.545e-105	349.0	COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2VIJK@28216|Betaproteobacteria,472TZ@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	dehH1	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
REGS1_k127_5209385_2	290397.Adeh_2205	3.413e-155	494.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
REGS1_k127_5209385_1	290397.Adeh_2249	2.511e-158	529.0	COG3181@1|root,COG3181@2|Bacteria,1MW18@1224|Proteobacteria,42U9Q@68525|delta/epsilon subdivisions,2WQ93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	Tripartite tricarboxylate transporter family receptor	-	-	-	-	-	-	-	-	-	-	-	-	TctC
REGS1_k127_5209385_0	290397.Adeh_2248	5.756e-243	758.0	COG3333@1|root,COG3333@2|Bacteria,1MUKR@1224|Proteobacteria,42M32@68525|delta/epsilon subdivisions,2WJA4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tripartite tricarboxylate transporter TctA family	-	-	-	ko:K07793	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.80.1	-	-	TctA
REGS1_k127_5209385_5	404589.Anae109_0554	1.916e-48	181.0	2D22U@1|root,32TC0@2|Bacteria,1MWUI@1224|Proteobacteria	1224|Proteobacteria	S	Tripartite tricarboxylate transporter TctB family	-	-	-	-	-	-	-	-	-	-	-	-	TctB
REGS1_k127_5209385_4	1297742.A176_04143	1.798e-59	211.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,42TZA@68525|delta/epsilon subdivisions,2WRHK@28221|Deltaproteobacteria,2Z03M@29|Myxococcales	28221|Deltaproteobacteria	S	CoA binding domain	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
REGS1_k127_5209385_7	243365.CV_1011	3.356e-06	51.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VGZ8@28216|Betaproteobacteria,2KQM1@206351|Neisseriales	28216|Betaproteobacteria	NT	ORF located using	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,MCPsignal,PAS_3
REGS1_k127_5210235_0	290397.Adeh_3405	1.286e-140	451.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2YUGZ@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
REGS1_k127_5210235_2	443144.GM21_2746	5.766e-81	278.0	COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,42TZD@68525|delta/epsilon subdivisions,2WQIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphonate ABC transporter, periplasmic	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_5210235_1	404589.Anae109_3900	1.154e-85	295.0	2EGEF@1|root,33A6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_527271_9	138119.DSY3736	0.0001924	46.0	COG0640@1|root,COG0640@2|Bacteria,1V007@1239|Firmicutes,24C15@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
REGS1_k127_527271_8	1174504.AJTN02000176_gene2070	7.653e-06	50.0	2BR4S@1|root,32K2S@2|Bacteria,1U1SU@1239|Firmicutes,4IB95@91061|Bacilli,1ZKR2@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_527271_4	290397.Adeh_3287	7.716e-193	613.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2WJRH@28221|Deltaproteobacteria,2YUPB@29|Myxococcales	28221|Deltaproteobacteria	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
REGS1_k127_527271_2	404589.Anae109_3346	5.37e-243	815.0	COG3975@1|root,COG3975@2|Bacteria,1MUHZ@1224|Proteobacteria,42YBA@68525|delta/epsilon subdivisions,2WUP5@28221|Deltaproteobacteria,2YX31@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase, M61	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M61
REGS1_k127_527271_1	404589.Anae109_3347	9.635e-263	847.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1NKQ0@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
REGS1_k127_527271_3	1144275.COCOR_02571	9.565e-208	660.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2YUHB@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
REGS1_k127_527271_7	404589.Anae109_2150	1.308e-101	342.0	COG0702@1|root,COG0702@2|Bacteria,1PGSR@1224|Proteobacteria,430YP@68525|delta/epsilon subdivisions,2WVUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
REGS1_k127_527271_5	290397.Adeh_3309	1.013e-146	473.0	2BKCR@1|root,32ETA@2|Bacteria,1RJ21@1224|Proteobacteria,430EX@68525|delta/epsilon subdivisions,2WVVF@28221|Deltaproteobacteria,2YUQK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_527271_6	404589.Anae109_3371	1.92e-123	416.0	COG0457@1|root,COG1714@1|root,COG0457@2|Bacteria,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	ko:K18481	-	M00670	-	-	ko00000,ko00002,ko02000	3.A.1.27.4,3.A.1.27.5	-	-	DUF2510,FHA,RDD
REGS1_k127_527271_0	290397.Adeh_3311	0.0	2937.0	COG0457@1|root,COG0457@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
REGS1_k127_5276780_11	1123240.ATVO01000003_gene147	5.155e-05	48.0	COG1086@1|root,COG1086@2|Bacteria,1RG1H@1224|Proteobacteria,2UI0G@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
REGS1_k127_5276780_3	290397.Adeh_4297	6.131e-139	445.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MCW@68525|delta/epsilon subdivisions,2WIYK@28221|Deltaproteobacteria,2YZY8@29|Myxococcales	28221|Deltaproteobacteria	JM	Nucleotidyl transferase	ddhA	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
REGS1_k127_5276780_4	1502850.FG91_02322	1.669e-121	412.0	COG0451@1|root,COG0451@2|Bacteria,1MV73@1224|Proteobacteria,2TU81@28211|Alphaproteobacteria,2K2D3@204457|Sphingomonadales	204457|Sphingomonadales	M	Polysaccharide biosynthesis protein	ddhB	-	4.2.1.45	ko:K01709	ko00520,map00520	-	R02426	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_5276780_0	290397.Adeh_4295	5.792e-227	728.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MA3@68525|delta/epsilon subdivisions,2WM1D@28221|Deltaproteobacteria,2Z1MB@29|Myxococcales	28221|Deltaproteobacteria	H	DegT/DnrJ/EryC1/StrS aminotransferase family	ddhC	-	1.17.1.1	ko:K12452	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_5276780_9	1303518.CCALI_01670	4.86e-14	84.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	waaE	-	-	ko:K12984,ko:K14597	ko00906,map00906	-	R07544,R07546	RC00262	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glyco_transf_7C,Glycos_transf_2
REGS1_k127_5276780_5	316067.Geob_1474	1.991e-80	282.0	COG0500@1|root,COG2226@2|Bacteria,1RF23@1224|Proteobacteria,42YRT@68525|delta/epsilon subdivisions,2WTIX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Caenorhabditis protein of unknown function, DUF268	-	-	-	-	-	-	-	-	-	-	-	-	DUF268
REGS1_k127_5276780_1	290397.Adeh_4287	9.817e-203	637.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_5276780_2	290397.Adeh_4286	9.726e-180	565.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2WIJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1312	Epimerase
REGS1_k127_5276780_6	483219.LILAB_03365	1.086e-58	231.0	COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,1N225@1224|Proteobacteria,42QDQ@68525|delta/epsilon subdivisions,2WM6B@28221|Deltaproteobacteria,2YVDU@29|Myxococcales	28221|Deltaproteobacteria	M	O-antigen ligase like membrane protein	-	-	-	ko:K18814	-	-	-	-	ko00000,ko02000	9.B.67.1	-	-	TPR_14,TPR_16,TPR_8,Wzy_C
REGS1_k127_5276780_10	449447.MAE_04250	1.545e-09	66.0	COG1569@1|root,COG1569@2|Bacteria,1G6Z6@1117|Cyanobacteria	1117|Cyanobacteria	S	Toxin-antitoxin system, toxin component, PIN family	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
REGS1_k127_5276780_7	240292.Ava_4168	6.704e-42	158.0	COG4634@1|root,COG4634@2|Bacteria,1GAZ4@1117|Cyanobacteria,1HTY4@1161|Nostocales	1117|Cyanobacteria	S	Mut7-C RNAse domain	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
REGS1_k127_5276780_8	317936.Nos7107_1461	4.442e-34	134.0	COG2442@1|root,COG2442@2|Bacteria,1G8FX@1117|Cyanobacteria,1HPIE@1161|Nostocales	1117|Cyanobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
REGS1_k127_5307455_1	290397.Adeh_3784	2.067e-76	263.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2YU3X@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
REGS1_k127_5307455_4	502025.Hoch_3345	4.222e-13	76.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
REGS1_k127_5307455_2	379066.GAU_0746	2.683e-45	183.0	COG1345@1|root,COG1572@1|root,COG1345@2|Bacteria,COG1572@2|Bacteria,1ZUQ5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5307455_0	290397.Adeh_3785	2.379e-90	301.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2WRKW@28221|Deltaproteobacteria,2YVUK@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
REGS1_k127_5311537_4	404589.Anae109_1019	5.335e-79	275.0	COG1073@1|root,COG1073@2|Bacteria,1MZUA@1224|Proteobacteria,431FI@68525|delta/epsilon subdivisions,2WX1E@28221|Deltaproteobacteria,2YV8K@29|Myxococcales	28221|Deltaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
REGS1_k127_5311537_6	1191523.MROS_0749	7.334e-24	115.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
REGS1_k127_5311537_5	502025.Hoch_4766	5.59e-54	209.0	2DBEV@1|root,2Z8UT@2|Bacteria,1N26S@1224|Proteobacteria,42WPK@68525|delta/epsilon subdivisions,2WS9G@28221|Deltaproteobacteria,2YV3S@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5311537_2	497964.CfE428DRAFT_1237	2.42e-111	374.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_5311537_0	290397.Adeh_0109	1.381e-239	752.0	COG2864@1|root,COG3005@1|root,COG2864@2|Bacteria,COG3005@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_5311537_1	497964.CfE428DRAFT_1237	1.763e-181	604.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_5311537_3	497964.CfE428DRAFT_1238	4.163e-82	291.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_5373331_5	404589.Anae109_0164	2.454e-65	228.0	COG0494@1|root,COG0494@2|Bacteria,1RD2C@1224|Proteobacteria,42TAG@68525|delta/epsilon subdivisions,2X5C6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_5373331_1	290397.Adeh_0159	2.105e-173	557.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,2YUTZ@29|Myxococcales	28221|Deltaproteobacteria	M	Mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
REGS1_k127_5373331_0	1297742.A176_01576	1.396e-179	573.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,42MET@68525|delta/epsilon subdivisions,2WITH@28221|Deltaproteobacteria,2YUC2@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	algC	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_5373331_3	404589.Anae109_0167	1.632e-100	339.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42S50@68525|delta/epsilon subdivisions,2X5NZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
REGS1_k127_5373331_2	404589.Anae109_2874	2.86e-135	451.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,sCache_2
REGS1_k127_5373331_6	404589.Anae109_0168	2.626e-55	201.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
REGS1_k127_5373331_7	404589.Anae109_0169	1.38e-48	188.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2WRCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
REGS1_k127_5373331_4	404589.Anae109_0170	1.033e-79	271.0	COG0811@1|root,COG0811@2|Bacteria,1NBED@1224|Proteobacteria,43BH4@68525|delta/epsilon subdivisions,2WRU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
REGS1_k127_5429479_6	290397.Adeh_3836	1.499e-18	91.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
REGS1_k127_5429479_5	379066.GAU_3037	5.14e-30	135.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
REGS1_k127_5429479_3	366602.Caul_1690	1.741e-37	156.0	COG1887@1|root,COG1887@2|Bacteria,1R476@1224|Proteobacteria,2U4I9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
REGS1_k127_5429479_0	290397.Adeh_3996	5.829e-127	414.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria	1224|Proteobacteria	J	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
REGS1_k127_5429479_1	290397.Adeh_3999	4.484e-92	308.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,2YXH0@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
REGS1_k127_5429479_2	290397.Adeh_4000	6.826e-41	167.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K21471,ko:K21473,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	LysM,NLPC_P60,SH3_3,SLT,Transglycosylas
REGS1_k127_5475213_7	290397.Adeh_1174	0.0004845	45.0	COG0348@1|root,COG0348@2|Bacteria,1MVFY@1224|Proteobacteria,42M8Q@68525|delta/epsilon subdivisions,2WNZJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	ccoG	-	-	-	-	-	-	-	-	-	-	-	Fer4_18,Fer4_5,FixG_C
REGS1_k127_5475213_4	404589.Anae109_1223	2.876e-24	111.0	COG5456@1|root,COG5456@2|Bacteria,1R398@1224|Proteobacteria,4338A@68525|delta/epsilon subdivisions,2WYHW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	FixH	-	-	-	-	-	-	-	-	-	-	-	-	FixH
REGS1_k127_5475213_6	1144275.COCOR_00352	1.796e-14	84.0	2EIZM@1|root,33CQT@2|Bacteria,1P1YR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5475213_1	404589.Anae109_4185	2.558e-168	534.0	COG3424@1|root,COG3424@2|Bacteria,1MUDX@1224|Proteobacteria,42S7Y@68525|delta/epsilon subdivisions,2WNF3@28221|Deltaproteobacteria,2YZHC@29|Myxococcales	28221|Deltaproteobacteria	Q	Chalcone and stilbene synthases, C-terminal domain	-	-	2.3.1.233	ko:K16167,ko:K19580	-	-	R10965	RC00004	ko00000,ko01000,ko01008	-	-	-	Chal_sti_synt_C,Chal_sti_synt_N
REGS1_k127_5475213_2	483219.LILAB_13325	1.878e-50	196.0	COG1755@1|root,COG1755@2|Bacteria,1N00M@1224|Proteobacteria,42V8A@68525|delta/epsilon subdivisions,2WRUF@28221|Deltaproteobacteria,2YUY3@29|Myxococcales	28221|Deltaproteobacteria	S	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	ko:K16168	-	-	-	-	ko00000,ko01008	-	-	-	ICMT
REGS1_k127_5475213_5	404589.Anae109_4184	1.246e-19	102.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acp	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_5475213_0	290397.Adeh_0389	1.422e-223	714.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria,2YUJE@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,PP-binding
REGS1_k127_5475213_3	1192034.CAP_8828	9.834e-34	140.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
REGS1_k127_5500323_0	95619.PM1_0204395	7.813e-32	143.0	COG3904@1|root,COG3904@2|Bacteria,1RK0H@1224|Proteobacteria,1SI4M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	periplasmic protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_554264_31	404589.Anae109_2350	6.848e-31	137.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2YZWP@29|Myxococcales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
REGS1_k127_554264_16	290397.Adeh_1481	4.861e-96	322.0	COG0642@1|root,COG2199@1|root,COG2205@2|Bacteria,COG3706@2|Bacteria,1NRP8@1224|Proteobacteria,439TT@68525|delta/epsilon subdivisions,2X575@28221|Deltaproteobacteria,2Z07H@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_554264_10	290397.Adeh_1480	6.595e-155	507.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42NZ5@68525|delta/epsilon subdivisions,2X6U7@28221|Deltaproteobacteria,2Z3CS@29|Myxococcales	28221|Deltaproteobacteria	H	tRNA nucleotidyltransferase domain 2 putative	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
REGS1_k127_554264_13	215803.DB30_4582	6.683e-109	364.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,43A1D@68525|delta/epsilon subdivisions,2X9Q2@28221|Deltaproteobacteria,2YWT5@29|Myxococcales	28221|Deltaproteobacteria	I	3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_554264_33	215803.DB30_4583	1.054e-10	70.0	2AA4H@1|root,30ZDF@2|Bacteria,1PMBJ@1224|Proteobacteria,434EA@68525|delta/epsilon subdivisions,2WYRK@28221|Deltaproteobacteria,2Z0FG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_554264_19	215803.DB30_7132	3.488e-79	274.0	COG4850@1|root,COG4850@2|Bacteria,1NN5H@1224|Proteobacteria,42XIW@68525|delta/epsilon subdivisions,2WT89@28221|Deltaproteobacteria,2YZTJ@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
REGS1_k127_554264_30	435590.BVU_0330	5.808e-32	130.0	COG2050@1|root,COG2050@2|Bacteria,4NM7W@976|Bacteroidetes,2FS5M@200643|Bacteroidia,4AQQC@815|Bacteroidaceae	976|Bacteroidetes	Q	phenylacetic acid degradation protein	paaI	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
REGS1_k127_554264_26	398767.Glov_2630	1.124e-44	175.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
REGS1_k127_554264_0	404589.Anae109_2392	0.0	2048.0	COG0454@1|root,COG1022@1|root,COG0456@2|Bacteria,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
REGS1_k127_554264_7	290397.Adeh_1436	3.416e-196	616.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2X1XD@28221|Deltaproteobacteria,2YWND@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	-	-	2.3.3.14	ko:K01655	ko00300,ko00620,ko01100,ko01120,ko01130,ko01210,ko01230,map00300,map00620,map01100,map01120,map01130,map01210,map01230	M00030,M00433	R00271	RC00004,RC00067,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
REGS1_k127_554264_15	404589.Anae109_2394	3.413e-98	353.0	COG0697@1|root,COG0697@2|Bacteria,1RBQS@1224|Proteobacteria,42U3T@68525|delta/epsilon subdivisions,2WQAP@28221|Deltaproteobacteria,2Z2VR@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_554264_25	404589.Anae109_2396	5.793e-51	189.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM amino acid-binding ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ACT
REGS1_k127_554264_20	404589.Anae109_2399	9.238e-64	235.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42PXM@68525|delta/epsilon subdivisions,2WMXU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	mcp	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
REGS1_k127_554264_22	290397.Adeh_1429	1.165e-57	210.0	COG3148@1|root,COG3148@2|Bacteria,1QJR1@1224|Proteobacteria,434CP@68525|delta/epsilon subdivisions,2X2Z2@28221|Deltaproteobacteria,2Z1IK@29|Myxococcales	28221|Deltaproteobacteria	S	DTW	-	-	-	-	-	-	-	-	-	-	-	-	DTW
REGS1_k127_554264_14	404589.Anae109_2404	1.001e-98	334.0	COG3503@1|root,COG3503@2|Bacteria	2|Bacteria	J	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
REGS1_k127_554264_8	404589.Anae109_2406	6.783e-183	579.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42NUN@68525|delta/epsilon subdivisions,2WJHN@28221|Deltaproteobacteria,2YWI0@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
REGS1_k127_554264_11	404589.Anae109_2407	8.629e-152	489.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,43AKQ@68525|delta/epsilon subdivisions,2X60P@28221|Deltaproteobacteria,2YWQF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_4
REGS1_k127_554264_18	404589.Anae109_2408	1.638e-80	272.0	28JYU@1|root,2Z9NZ@2|Bacteria,1N5J2@1224|Proteobacteria,42UJJ@68525|delta/epsilon subdivisions,2X7XY@28221|Deltaproteobacteria,2Z2S3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_554264_17	1232410.KI421425_gene1562	1.038e-83	297.0	COG5557@1|root,COG5557@2|Bacteria,1QURB@1224|Proteobacteria,43BT1@68525|delta/epsilon subdivisions,2X73S@28221|Deltaproteobacteria,43SR9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pfam Polysulphide reductase, NrfD	actF	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_554264_27	1232410.KI421425_gene1563	7.596e-44	166.0	COG2010@1|root,COG2010@2|Bacteria,1PWTD@1224|Proteobacteria,437B9@68525|delta/epsilon subdivisions,2X9ZG@28221|Deltaproteobacteria,43V90@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
REGS1_k127_554264_6	1232410.KI421425_gene1564	6.235e-199	627.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
REGS1_k127_554264_1	1232410.KI421425_gene1565	0.0	1116.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,43TY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
REGS1_k127_554264_24	1232410.KI421425_gene1566	1.573e-53	210.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_554264_23	1232410.KI421425_gene1567	9.573e-56	210.0	COG4654@1|root,COG4654@2|Bacteria,1NJV5@1224|Proteobacteria,42XIC@68525|delta/epsilon subdivisions,2WTEX@28221|Deltaproteobacteria,43UUU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
REGS1_k127_554264_12	404589.Anae109_2409	4.152e-135	457.0	COG1032@1|root,COG1032@2|Bacteria,1RF63@1224|Proteobacteria,42S8Y@68525|delta/epsilon subdivisions,2WNX1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_554264_21	404589.Anae109_2412	4.936e-62	220.0	2ESNI@1|root,33K73@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
REGS1_k127_554264_5	290397.Adeh_4234	1.194e-221	696.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,2YUEU@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
REGS1_k127_554264_28	290397.Adeh_1572	7.201e-42	162.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_554264_2	404589.Anae109_2417	0.0	1043.0	COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Peptidase M1 membrane alanine aminopeptidase	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3458,DUF3458_C,ERAP1_C,Peptidase_M1
REGS1_k127_554264_3	290397.Adeh_1417	1.003e-279	874.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42PMK@68525|delta/epsilon subdivisions,2X5G7@28221|Deltaproteobacteria,2Z35F@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_554264_9	404589.Anae109_2425	2.81e-158	515.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
REGS1_k127_554264_4	290397.Adeh_1400	3.179e-274	854.0	COG0460@1|root,COG2021@1|root,COG0460@2|Bacteria,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2WJRJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Homoserine_dh,NAD_binding_3
REGS1_k127_5555522_7	290397.Adeh_2518	1.856e-46	168.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,2YUEF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
REGS1_k127_5555522_3	404589.Anae109_1348	5.798e-74	254.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,2YVSW@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
REGS1_k127_5555522_8	502025.Hoch_4102	2.576e-43	175.0	COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,42TZY@68525|delta/epsilon subdivisions,2WQKV@28221|Deltaproteobacteria,2Z1HI@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_5555522_4	290397.Adeh_2515	6.765e-62	228.0	COG0500@1|root,COG2226@2|Bacteria,1QYG9@1224|Proteobacteria,43CCD@68525|delta/epsilon subdivisions,2X7NC@28221|Deltaproteobacteria,2Z1M8@29|Myxococcales	28221|Deltaproteobacteria	Q	tRNA methyltransferase complex GCD14 subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
REGS1_k127_5555522_5	404589.Anae109_1354	3.851e-57	225.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,2Z24M@29|Myxococcales	28221|Deltaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
REGS1_k127_5555522_11	253839.SSNG_03489	6.028e-07	59.0	COG1250@1|root,COG1250@2|Bacteria,2GPFP@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase	paaH	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
REGS1_k127_5555522_6	649638.Trad_1402	9.281e-57	204.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
REGS1_k127_5555522_9	1126627.BAWE01000002_gene553	6.915e-13	71.0	2BUZT@1|root,32QCC@2|Bacteria,1Q8TE@1224|Proteobacteria,2UYDE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5555522_1	404589.Anae109_3530	1.335e-154	505.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Phospholip_A2_3,RHS_repeat
REGS1_k127_5555522_2	290397.Adeh_2841	2.943e-142	456.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
REGS1_k127_5555522_0	404589.Anae109_2771	2.96e-322	996.0	COG1389@1|root,COG1389@2|Bacteria,1R6T0@1224|Proteobacteria,42YI1@68525|delta/epsilon subdivisions,2WTHV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Relaxes both positive and negative superturns and exhibits a strong decatenase activity	top6B	-	5.99.1.3	ko:K03167	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	HATPase_c,HATPase_c_3,Topo-VIb_trans
REGS1_k127_5599091_1	404589.Anae109_2513	3.616e-81	272.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2YVC1@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
REGS1_k127_5599091_0	290397.Adeh_1253	4.117e-122	408.0	COG1233@1|root,COG1233@2|Bacteria,1Q2HN@1224|Proteobacteria,4384H@68525|delta/epsilon subdivisions,2X3EF@28221|Deltaproteobacteria,2YVQ0@29|Myxococcales	28221|Deltaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
REGS1_k127_5602446_1	290397.Adeh_3846	2.86e-128	411.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42Y66@68525|delta/epsilon subdivisions,2WU83@28221|Deltaproteobacteria,2YX71@29|Myxococcales	28221|Deltaproteobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_5602446_0	404589.Anae109_3957	1.335e-194	627.0	COG0312@1|root,COG0312@2|Bacteria,1RBJZ@1224|Proteobacteria,42YBE@68525|delta/epsilon subdivisions,2WUP7@28221|Deltaproteobacteria,2YZ4Y@29|Myxococcales	28221|Deltaproteobacteria	L	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_5605046_1	404589.Anae109_4326	4.992e-183	577.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,2YUC0@29|Myxococcales	28221|Deltaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
REGS1_k127_5605046_6	404589.Anae109_4325	1.54e-93	329.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,42U7C@68525|delta/epsilon subdivisions,2WQM9@28221|Deltaproteobacteria,2Z33Z@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_5605046_3	290397.Adeh_4177	1.976e-143	460.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2X6EH@28221|Deltaproteobacteria,2Z3AS@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
REGS1_k127_5605046_5	404589.Anae109_4319	1.151e-108	356.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,2YYFF@29|Myxococcales	28221|Deltaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
REGS1_k127_5605046_0	290397.Adeh_4174	0.0	1013.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2YTT7@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
REGS1_k127_5605046_2	290397.Adeh_4173	9.287e-154	488.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,2YUE2@29|Myxococcales	28221|Deltaproteobacteria	H	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
REGS1_k127_5605046_7	404589.Anae109_4316	3.783e-61	239.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WPT4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
REGS1_k127_5605046_4	290397.Adeh_4171	8.839e-115	380.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
REGS1_k127_5638041_1	290397.Adeh_0837	1.705e-85	295.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5638041_0	404589.Anae109_0896	4.134e-142	460.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
REGS1_k127_5639688_13	404589.Anae109_4465	5.942e-89	301.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,2YVMB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
REGS1_k127_5639688_4	404589.Anae109_4466	2.771e-218	699.0	COG0642@1|root,COG4936@1|root,COG2205@2|Bacteria,COG4936@2|Bacteria,1NRP8@1224|Proteobacteria,42MZW@68525|delta/epsilon subdivisions,2WIV1@28221|Deltaproteobacteria,2YUVS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PocR
REGS1_k127_5639688_10	404589.Anae109_4467	3.67e-113	372.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,42R57@68525|delta/epsilon subdivisions,2WN5Y@28221|Deltaproteobacteria,2YUYK@29|Myxococcales	28221|Deltaproteobacteria	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
REGS1_k127_5639688_18	1144275.COCOR_07842	1.711e-44	183.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2Z2WE@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
REGS1_k127_5639688_2	290397.Adeh_4323	2.756e-310	966.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria,2YUK7@29|Myxococcales	28221|Deltaproteobacteria	KL	SMART helicase c2	yoaA	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
REGS1_k127_5639688_3	290397.Adeh_4326	1.583e-229	747.0	COG0683@1|root,COG0683@2|Bacteria,1R8IG@1224|Proteobacteria,42N7H@68525|delta/epsilon subdivisions,2WIUQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	ABC-type branched-chain amino acid transport	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC,Peripla_BP_6,TPR_16,TPR_6
REGS1_k127_5639688_7	483219.LILAB_05045	9.833e-139	450.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2YXG3@29|Myxococcales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
REGS1_k127_5639688_1	290397.Adeh_4328	0.0	1060.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YU6B@29|Myxococcales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
REGS1_k127_5639688_15	290397.Adeh_4329	8.332e-73	253.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
REGS1_k127_5639688_6	404589.Anae109_4476	1.744e-161	517.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2YUQ9@29|Myxococcales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
REGS1_k127_5639688_17	290397.Adeh_4331	1.459e-62	223.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	2.7.11.1	ko:K12132,ko:K20543	-	-	-	-	ko00000,ko01000,ko01001,ko02000	1.B.55.3	-	-	AAA_16,NfrA_C,Pkinase,TPR_10,TPR_12,TPR_14,TPR_16,TPR_19,TPR_8
REGS1_k127_5639688_0	404589.Anae109_4478	0.0	1814.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria,2YUID@29|Myxococcales	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
REGS1_k127_5639688_12	290397.Adeh_4333	2.168e-96	329.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2YVS3@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_5639688_9	290397.Adeh_4334	3.539e-117	388.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_5639688_11	404589.Anae109_4481	2.682e-100	350.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,2YVIS@29|Myxococcales	28221|Deltaproteobacteria	M	SurA N-terminal domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
REGS1_k127_5639688_8	290397.Adeh_4336	4.979e-137	443.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,2YV17@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
REGS1_k127_5639688_14	290397.Adeh_0348	1.222e-78	270.0	COG1073@1|root,COG1073@2|Bacteria,1RGMF@1224|Proteobacteria	1224|Proteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
REGS1_k127_5639688_5	290397.Adeh_4337	2.415e-197	620.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,2YU7R@29|Myxococcales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
REGS1_k127_5639688_16	290397.Adeh_4338	1.133e-63	223.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
REGS1_k127_5639688_19	290397.Adeh_4339	5.252e-26	109.0	COG0636@1|root,COG0636@2|Bacteria	2|Bacteria	C	ATP hydrolysis coupled proton transport	atpE	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02110,ko:K02124	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157,M00159	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1,3.A.2.2,3.A.2.3	-	iHN637.CLJU_RS01165	ATP-synt_C
REGS1_k127_5640331_0	404589.Anae109_2074	0.0	1146.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,2YXV4@29|Myxococcales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
REGS1_k127_5708330_4	404589.Anae109_2068	2.99e-12	74.0	2ET5I@1|root,33KPK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
REGS1_k127_5708330_2	290397.Adeh_3392	9.678e-104	366.0	COG3303@1|root,COG3303@2|Bacteria,1NKAH@1224|Proteobacteria,431V2@68525|delta/epsilon subdivisions,2WWRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	8 heme-binding sites	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_5708330_3	290397.Adeh_3390	6.718e-30	126.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,2YVWK@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_5708330_0	290397.Adeh_3389	1.027e-245	771.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42V54@68525|delta/epsilon subdivisions,2WSDI@28221|Deltaproteobacteria,2YWJM@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
REGS1_k127_5729547_0	1122939.ATUD01000002_gene1444	6.614e-18	98.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4CPTS@84995|Rubrobacteria	84995|Rubrobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_5756358_22	1242864.D187_006986	6.975e-65	225.0	COG0010@1|root,COG0010@2|Bacteria,1RCQX@1224|Proteobacteria,42R4M@68525|delta/epsilon subdivisions,2X5RQ@28221|Deltaproteobacteria,2YYRW@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the arginase family	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
REGS1_k127_5756358_21	290397.Adeh_2522	2.936e-73	259.0	COG0775@1|root,COG0775@2|Bacteria	2|Bacteria	F	adenosylhomocysteine nucleosidase activity	mqnB	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.4.2.1,3.2.2.26,3.2.2.9	ko:K01243,ko:K03784,ko:K11783	ko00130,ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,ko01230,map00130,map00230,map00240,map00270,map00760,map01100,map01110,map01230	M00034,M00609	R00194,R01401,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R08587,R10244	RC00033,RC00063,RC00122,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_5756358_6	404589.Anae109_1744	2.369e-200	635.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,42PS0@68525|delta/epsilon subdivisions,2WJU3@28221|Deltaproteobacteria,2YYFX@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M20/M25/M40	-	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
REGS1_k127_5756358_23	290397.Adeh_2074	5.536e-58	202.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_5756358_2	404589.Anae109_3051	3.493e-305	950.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,1MUV9@1224|Proteobacteria,43DIW@68525|delta/epsilon subdivisions,2X8Q7@28221|Deltaproteobacteria,2YUMS@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fumB	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
REGS1_k127_5756358_11	1120963.KB894494_gene3532	1.017e-136	469.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,2PZY5@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_8,PAS_9
REGS1_k127_5756358_24	1121438.JNJA01000012_gene1609	5.406e-57	210.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_5756358_14	398767.Glov_3545	4.548e-125	413.0	COG1304@1|root,COG1304@2|Bacteria,1MUEZ@1224|Proteobacteria,42N2F@68525|delta/epsilon subdivisions,2WKXN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM FMN-dependent alpha-hydroxy acid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_dh
REGS1_k127_5756358_8	290397.Adeh_0533	7.806e-196	640.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MXG@68525|delta/epsilon subdivisions,2WJ6G@28221|Deltaproteobacteria,2Z039@29|Myxococcales	28221|Deltaproteobacteria	H	Aminotransferase class I and II	-	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_5756358_1	290397.Adeh_2059	0.0	1053.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_5756358_25	880072.Desac_2119	6.964e-55	203.0	COG1148@1|root,COG1148@2|Bacteria,1RB0H@1224|Proteobacteria,42QQV@68525|delta/epsilon subdivisions,2WN7E@28221|Deltaproteobacteria,2MRI3@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_5756358_28	290397.Adeh_2982	1.022e-24	118.0	2E3XG@1|root,32YUI@2|Bacteria,1N8RF@1224|Proteobacteria	1224|Proteobacteria	S	Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
REGS1_k127_5756358_12	290397.Adeh_2045	3.104e-129	432.0	COG2755@1|root,COG2755@2|Bacteria,1Q3HJ@1224|Proteobacteria,439AC@68525|delta/epsilon subdivisions,2X4HW@28221|Deltaproteobacteria,2YZ1R@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
REGS1_k127_5756358_16	290397.Adeh_2030	1.278e-103	344.0	COG3698@1|root,COG3698@2|Bacteria,1NM1P@1224|Proteobacteria,42QPU@68525|delta/epsilon subdivisions,2WMZ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
REGS1_k127_5756358_3	404589.Anae109_1780	5.785e-285	883.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,42M9F@68525|delta/epsilon subdivisions,2WJNB@28221|Deltaproteobacteria,2YU00@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_5756358_30	404589.Anae109_1189	1.001e-18	94.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451,FHA,Yop-YscD_cpl
REGS1_k127_5756358_26	404589.Anae109_1783	3.477e-45	190.0	COG0537@1|root,COG0537@2|Bacteria,1NMG6@1224|Proteobacteria	1224|Proteobacteria	FG	adenosine 5'-monophosphoramidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5756358_0	404589.Anae109_1787	0.0	1319.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2Z2XH@29|Myxococcales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
REGS1_k127_5756358_15	404589.Anae109_1788	1.299e-116	389.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,2YZVB@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_5756358_13	404589.Anae109_1793	4.086e-128	417.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria,2YXVU@29|Myxococcales	28221|Deltaproteobacteria	P	Membrane protein, TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
REGS1_k127_5756358_10	290397.Adeh_2012	8.845e-150	478.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,42MPM@68525|delta/epsilon subdivisions,2WKPX@28221|Deltaproteobacteria,2YURJ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
REGS1_k127_5756358_5	290397.Adeh_2011	1.025e-224	711.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,2Z0GM@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
REGS1_k127_5756358_19	290397.Adeh_2010	1.116e-76	261.0	COG1913@1|root,COG1913@2|Bacteria,1NEU5@1224|Proteobacteria,42WCP@68525|delta/epsilon subdivisions,2X5BA@28221|Deltaproteobacteria,2Z2ND@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
REGS1_k127_5756358_4	290397.Adeh_2009	5.348e-244	764.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
REGS1_k127_5756358_18	641491.DND132_1542	1.958e-84	289.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42M97@68525|delta/epsilon subdivisions,2WJB4@28221|Deltaproteobacteria,2M9HU@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	hmcB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,Fer4_7
REGS1_k127_5756358_7	404589.Anae109_1801	1.659e-196	619.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42P2Q@68525|delta/epsilon subdivisions,2WKC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
REGS1_k127_5756358_17	290397.Adeh_2005	7.734e-95	334.0	COG0509@1|root,COG0509@2|Bacteria,1RC80@1224|Proteobacteria,42R79@68525|delta/epsilon subdivisions,2WN04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
REGS1_k127_5756358_20	404589.Anae109_1804	1.796e-74	258.0	COG0509@1|root,COG0509@2|Bacteria,1NRFW@1224|Proteobacteria,42ZAN@68525|delta/epsilon subdivisions,2WUQI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
REGS1_k127_5756358_9	404589.Anae109_1805	2.214e-184	584.0	COG3005@1|root,COG3005@2|Bacteria,1QYG3@1224|Proteobacteria,43CC8@68525|delta/epsilon subdivisions,2X7N4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c3	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_5756358_32	290397.Adeh_2001	3.557e-15	79.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_5780495_3	404589.Anae109_2689	1.044e-68	239.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2YV00@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_5780495_6	1144275.COCOR_05050	2.1e-32	147.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	aglU	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Trans_reg_C,WD40
REGS1_k127_5780495_1	404589.Anae109_2691	2.792e-227	715.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,42MTS@68525|delta/epsilon subdivisions,2WJ50@28221|Deltaproteobacteria,2YU50@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
REGS1_k127_5780495_7	404589.Anae109_2692	4.747e-25	108.0	COG1734@1|root,COG1734@2|Bacteria,1Q0U6@1224|Proteobacteria,42W75@68525|delta/epsilon subdivisions,2WR7B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM zinc finger, DksA TraR C4-type	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
REGS1_k127_5780495_4	1278073.MYSTI_03464	7.589e-40	162.0	COG0848@1|root,COG0848@2|Bacteria,1NA7P@1224|Proteobacteria,42V1Q@68525|delta/epsilon subdivisions,2WSGW@28221|Deltaproteobacteria,2YY8R@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
REGS1_k127_5780495_5	215803.DB30_4917	1.407e-38	151.0	COG0848@1|root,COG0848@2|Bacteria,1NKZC@1224|Proteobacteria,43BCT@68525|delta/epsilon subdivisions,2X6RQ@28221|Deltaproteobacteria,2Z3CG@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
REGS1_k127_5780495_2	378806.STAUR_5107	1.346e-75	259.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,43BH3@68525|delta/epsilon subdivisions,2X214@28221|Deltaproteobacteria,2YZ2T@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
REGS1_k127_5780495_0	290397.Adeh_2699	0.0	1237.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,2YU14@29|Myxococcales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
REGS1_k127_5780495_8	404589.Anae109_2694	5.151e-15	75.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2YVFF@29|Myxococcales	28221|Deltaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
REGS1_k127_5799519_1	290397.Adeh_2257	1.806e-275	872.0	COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1MXH9@1224|Proteobacteria,42N7P@68525|delta/epsilon subdivisions,2WMCJ@28221|Deltaproteobacteria,2YU2S@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised conserved protein (DUF2156)	-	-	2.3.2.3	ko:K07027,ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00726	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	2.A.1.3.37,4.D.2	-	-	DUF2156,LPG_synthase_TM
REGS1_k127_5799519_5	316067.Geob_1351	3.137e-97	325.0	COG0437@1|root,COG0437@2|Bacteria,1PF80@1224|Proteobacteria,439WY@68525|delta/epsilon subdivisions,2X26N@28221|Deltaproteobacteria,43VKJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
REGS1_k127_5799519_0	443143.GM18_2394	0.0	1432.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MI4@68525|delta/epsilon subdivisions,2WKB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
REGS1_k127_5799519_2	290397.Adeh_0712	1.254e-203	644.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria,2YTXD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
REGS1_k127_5799519_7	404589.Anae109_0754	2.175e-88	317.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria,2YV6W@29|Myxococcales	28221|Deltaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
REGS1_k127_5799519_6	404589.Anae109_0755	3.065e-96	324.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,2YV5Y@29|Myxococcales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
REGS1_k127_5799519_4	290397.Adeh_0715	1.24e-113	370.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2WK1K@28221|Deltaproteobacteria,2YVBU@29|Myxococcales	28221|Deltaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0388	His_biosynth
REGS1_k127_5799519_3	290397.Adeh_0716	5.082e-141	450.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2YUN8@29|Myxococcales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
REGS1_k127_5799519_8	1033736.CAHK01000003_gene2739	2.943e-35	143.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4FAAF@85019|Brevibacteriaceae	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
REGS1_k127_5799519_9	1128421.JAGA01000003_gene3607	1.5e-06	51.0	COG0139@1|root,COG0140@1|root,COG0139@2|Bacteria,COG0140@2|Bacteria,2NPDP@2323|unclassified Bacteria	2|Bacteria	E	Phosphoribosyl-AMP cyclohydrolase	hisE	GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16	ko:K01496,ko:K01497,ko:K01523,ko:K01814,ko:K11755	ko00340,ko00740,ko00790,ko01100,ko01110,ko01230,ko02024,map00340,map00740,map00790,map01100,map01110,map01230,map02024	M00026,M00125	R00425,R04035,R04037,R04640	RC00002,RC00293,RC00945,RC01055,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_0880,iECW_1372.ECW_m2186,iEKO11_1354.EKO11_1768,iHN637.CLJU_RS05760,iSB619.SA_RS14110,iUMN146_1321.UM146_06665,iWFL_1372.ECW_m2186,iYO844.BSU34860	PRA-CH,PRA-PH
REGS1_k127_5799519_10	290397.Adeh_0718	0.0001414	46.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
REGS1_k127_5810612_5	290397.Adeh_4270	2.317e-18	93.0	COG1196@1|root,COG1196@2|Bacteria,1QX9X@1224|Proteobacteria,43018@68525|delta/epsilon subdivisions,2WVD9@28221|Deltaproteobacteria,2YW2N@29|Myxococcales	28221|Deltaproteobacteria	D	Domain of unknown function (DUF4175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
REGS1_k127_5810612_2	290397.Adeh_4271	4.663e-80	273.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_5810612_1	404589.Anae109_4131	1.161e-87	299.0	28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria	1224|Proteobacteria	S	PFAM RES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RES
REGS1_k127_5810612_6	1408418.JNJH01000107_gene1550	7.984e-15	83.0	COG1569@1|root,COG1569@2|Bacteria,1RE43@1224|Proteobacteria	1224|Proteobacteria	S	nucleic acid-binding protein contains PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
REGS1_k127_5810612_0	290397.Adeh_1954	1.853e-141	455.0	COG0451@1|root,COG0451@2|Bacteria,1QX8V@1224|Proteobacteria,43C1V@68525|delta/epsilon subdivisions,2X5FV@28221|Deltaproteobacteria,2Z35E@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_5831279_5	321332.CYB_0789	4.685e-07	54.0	COG4671@1|root,COG4671@2|Bacteria,1G142@1117|Cyanobacteria,1GYRP@1129|Synechococcus	1117|Cyanobacteria	S	Glycosyl Transferase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5831279_0	290397.Adeh_3300	7.071e-213	669.0	COG0031@1|root,COG0517@1|root,COG0031@2|Bacteria,COG0517@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YYV5@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47,4.2.1.22	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00035,M00338	R00891,R00897,R01290,R03601,R04859,R04942	RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
REGS1_k127_5831279_1	290397.Adeh_3096	2.4e-123	407.0	COG0667@1|root,COG0667@2|Bacteria,1NSK8@1224|Proteobacteria	1224|Proteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_5831279_4	47763.JNZA01000038_gene1734	9.454e-11	68.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	tcrX	GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0098771	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_5831279_2	530564.Psta_0612	9.58e-81	283.0	COG3829@1|root,COG3829@2|Bacteria,2J54R@203682|Planctomycetes	2|Bacteria	KT	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
REGS1_k127_5859978_3	448385.sce4797	5.658e-86	313.0	COG0852@1|root,COG3261@1|root,COG0852@2|Bacteria,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,2YZIA@29|Myxococcales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
REGS1_k127_5859978_1	448385.sce4798	3.073e-139	467.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,2YZXM@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	ehrD	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
REGS1_k127_5859978_4	448385.sce4799	1.382e-32	144.0	295Z9@1|root,2ZTA1@2|Bacteria,1P4NQ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	-
REGS1_k127_5859978_2	448385.sce4800	8.721e-88	323.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,42NHI@68525|delta/epsilon subdivisions,2WJ3D@28221|Deltaproteobacteria,2Z0BP@29|Myxococcales	28221|Deltaproteobacteria	C	NADH dehydrogenase	ehrB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0374,iAF987.Gmet_2600	NADHdh
REGS1_k127_5859978_0	448385.sce4801	1.334e-238	758.0	COG1009@1|root,COG1009@2|Bacteria,1QV11@1224|Proteobacteria,43BNG@68525|delta/epsilon subdivisions,2X839@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	Proton-conducting membrane transporter	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
REGS1_k127_5879910_1	1499967.BAYZ01000013_gene6451	5.396e-122	396.0	COG0033@1|root,COG0033@2|Bacteria,2NS5G@2323|unclassified Bacteria	2|Bacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pgm	GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAPECO1_1312.APECO1_1376,iECED1_1282.ECED1_0670,iECNA114_1301.ECNA114_0627,iECOK1_1307.ECOK1_0699,iECP_1309.ECP_0709,iECS88_1305.ECS88_0725,iJN678.pgm,iLF82_1304.LF82_1632,iNRG857_1313.NRG857_03110,iUMN146_1321.UM146_14115,iYL1228.KPN_00711	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_5879910_0	867845.KI911784_gene2379	8.437e-146	484.0	COG1178@1|root,COG1178@2|Bacteria,2G5Q0@200795|Chloroflexi,375FG@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
REGS1_k127_5879910_2	717231.Flexsi_0939	1.238e-28	117.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	fbpA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
REGS1_k127_5881700_2	28229.ND2E_1925	1.423e-50	188.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,1S5NE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
REGS1_k127_5881700_3	1123228.AUIH01000003_gene918	1.555e-42	177.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,1RXRJ@1236|Gammaproteobacteria,1XPVP@135619|Oceanospirillales	135619|Oceanospirillales	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
REGS1_k127_5881700_4	926550.CLDAP_36950	1.152e-35	157.0	COG4591@1|root,COG4591@2|Bacteria,2G85M@200795|Chloroflexi	200795|Chloroflexi	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
REGS1_k127_5881700_1	518766.Rmar_2536	2.621e-70	263.0	COG1136@1|root,COG1136@2|Bacteria,4NE5N@976|Bacteroidetes,1FIVB@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_5881700_5	765912.Thimo_2522	1.662e-14	86.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,1RSN5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5881700_0	404380.Gbem_1478	1.614e-311	990.0	COG3391@1|root,COG3391@2|Bacteria,1R6BZ@1224|Proteobacteria	1224|Proteobacteria	M	phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase,Phosphoesterase
REGS1_k127_5889095_4	1408445.JHXP01000006_gene102	5.393e-09	64.0	COG2706@1|root,COG3419@1|root,COG5492@1|root,COG2706@2|Bacteria,COG3419@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Big_2,Neisseria_PilC
REGS1_k127_5889095_0	404589.Anae109_4215	1.602e-216	677.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,2YUNU@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
REGS1_k127_5889095_2	404589.Anae109_4216	2.588e-99	349.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WNAZ@28221|Deltaproteobacteria,2Z2YU@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
REGS1_k127_5889095_3	404589.Anae109_4217	3.777e-50	181.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
REGS1_k127_5889095_1	404589.Anae109_4218	7.933e-113	371.0	COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria,42W6K@68525|delta/epsilon subdivisions,2WS34@28221|Deltaproteobacteria,2YZXI@29|Myxococcales	28221|Deltaproteobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
REGS1_k127_5889095_6	1158318.ATXC01000001_gene948	5.509e-06	50.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	CarbopepD_reg_2,TonB_2,TonB_C
REGS1_k127_5938844_2	290397.Adeh_4248	1.036e-09	63.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2YVH0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
REGS1_k127_5938844_1	404589.Anae109_4396	2.21e-107	362.0	COG2267@1|root,COG2267@2|Bacteria,1PXRQ@1224|Proteobacteria,434SS@68525|delta/epsilon subdivisions,2X90B@28221|Deltaproteobacteria,2Z19P@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
REGS1_k127_5938844_0	404589.Anae109_4395	4.991e-186	591.0	COG2770@1|root,COG5000@1|root,COG2770@2|Bacteria,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,42YZ2@68525|delta/epsilon subdivisions,2X7NZ@28221|Deltaproteobacteria,2Z3HA@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_5938844_3	861299.J421_0962	5.212e-07	62.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
REGS1_k127_5961061_0	290397.Adeh_3350	5.333e-272	842.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_5961061_1	290397.Adeh_3348	1.04e-81	277.0	COG2519@1|root,COG2519@2|Bacteria	2|Bacteria	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,SAM_MT,Spermine_synth
REGS1_k127_5962731_0	861299.J421_3508	3.531e-186	591.0	COG2256@1|root,COG2256@2|Bacteria,1ZTCA@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
REGS1_k127_5962731_1	861299.J421_3506	1.521e-109	366.0	COG2262@1|root,COG2262@2|Bacteria,1ZSYM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
REGS1_k127_5971867_17	404589.Anae109_0456	8.817e-89	294.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YTSX@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
REGS1_k127_5971867_9	290397.Adeh_3965	3.603e-115	386.0	COG2979@1|root,COG2979@2|Bacteria	2|Bacteria	T	Protein of unknown function (DUF533)	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	LETM1,TerB
REGS1_k127_5971867_3	290397.Adeh_3966	1.175e-169	548.0	COG1413@1|root,COG1413@2|Bacteria,1QAUN@1224|Proteobacteria,435B4@68525|delta/epsilon subdivisions,2WZNB@28221|Deltaproteobacteria,2Z2F0@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
REGS1_k127_5971867_21	290397.Adeh_3967	3.075e-67	239.0	29WSR@1|root,30IE2@2|Bacteria,1QX7C@1224|Proteobacteria,43C09@68525|delta/epsilon subdivisions,2X7B0@28221|Deltaproteobacteria,2YWMK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5971867_4	290397.Adeh_3968	4.276e-146	477.0	COG2379@1|root,COG2379@2|Bacteria,1MVIK@1224|Proteobacteria,42Q1H@68525|delta/epsilon subdivisions,2WK7W@28221|Deltaproteobacteria,2YVDS@29|Myxococcales	28221|Deltaproteobacteria	G	PFAM MOFRL domain protein	-	-	2.7.1.165	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	M00346	R08572	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4147,MOFRL
REGS1_k127_5971867_7	404589.Anae109_0449	5.348e-126	422.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,2YUSE@29|Myxococcales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
REGS1_k127_5971867_1	290397.Adeh_3970	1.886e-195	644.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2WJ9B@28221|Deltaproteobacteria,2YV48@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
REGS1_k127_5971867_11	290397.Adeh_3971	1.911e-111	363.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2YURC@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
REGS1_k127_5971867_14	404589.Anae109_0446	1.594e-92	323.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
REGS1_k127_5971867_15	566466.NOR53_798	8.441e-92	317.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1J96D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Rhodanese,Sulf_transp
REGS1_k127_5971867_23	864051.BurJ1DRAFT_2686	5.379e-49	198.0	COG2391@1|root,COG2391@2|Bacteria,1N3PQ@1224|Proteobacteria,2VXAQ@28216|Betaproteobacteria,1KP4P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_5971867_10	864051.BurJ1DRAFT_2685	7.291e-115	401.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_5971867_2	566466.NOR53_2152	1.197e-172	554.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
REGS1_k127_5971867_16	290397.Adeh_3973	4.003e-89	312.0	COG1573@1|root,COG1573@2|Bacteria,1Q2FJ@1224|Proteobacteria,43F3W@68525|delta/epsilon subdivisions,2X3BI@28221|Deltaproteobacteria,2YV9I@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_5971867_20	483219.LILAB_04490	1.481e-69	255.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria,2Z17Q@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
REGS1_k127_5971867_19	1304885.AUEY01000005_gene892	4.41e-82	282.0	COG0598@1|root,COG0598@2|Bacteria,1RGGI@1224|Proteobacteria,42UX4@68525|delta/epsilon subdivisions,2WQYH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Mg2 transporter protein CorA family protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
REGS1_k127_5971867_5	404589.Anae109_0440	5.826e-136	443.0	COG1638@1|root,COG1638@2|Bacteria,1PJFW@1224|Proteobacteria,42PXK@68525|delta/epsilon subdivisions,2WJFU@28221|Deltaproteobacteria,2Z1WI@29|Myxococcales	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
REGS1_k127_5971867_12	290397.Adeh_3980	3.695e-108	359.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,42Q81@68525|delta/epsilon subdivisions,2WIJ3@28221|Deltaproteobacteria,2Z2J1@29|Myxococcales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
REGS1_k127_5971867_0	404589.Anae109_0438	6.625e-268	836.0	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,2YWE1@29|Myxococcales	28221|Deltaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
REGS1_k127_5971867_13	290397.Adeh_3982	2.168e-101	340.0	2D6MI@1|root,30AQT@2|Bacteria,1P8HC@1224|Proteobacteria	1224|Proteobacteria	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
REGS1_k127_5971867_8	404589.Anae109_0436	9.67e-122	409.0	COG2518@1|root,COG2518@2|Bacteria,1NMMQ@1224|Proteobacteria,42ZGE@68525|delta/epsilon subdivisions,2WUVC@28221|Deltaproteobacteria,2YW9A@29|Myxococcales	28221|Deltaproteobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
REGS1_k127_5971867_22	497964.CfE428DRAFT_3850	1.589e-64	240.0	28J0S@1|root,2Z8XX@2|Bacteria,46SX2@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5971867_18	246197.MXAN_0224	3.539e-86	304.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
REGS1_k127_5971867_24	404589.Anae109_0433	1.933e-24	102.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter, ATP-binding protein	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_5972184_1	404589.Anae109_2975	6.609e-23	113.0	COG5485@1|root,COG5485@2|Bacteria,1N1VS@1224|Proteobacteria,430HY@68525|delta/epsilon subdivisions,2WXSV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
REGS1_k127_5972184_0	404589.Anae109_0221	1.407e-156	499.0	COG0477@1|root,COG0477@2|Bacteria,1NS3F@1224|Proteobacteria,42X52@68525|delta/epsilon subdivisions,2WUPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_5980745_2	642227.HA49_20270	2.208e-05	49.0	2AGMU@1|root,316V4@2|Bacteria,1RJBQ@1224|Proteobacteria,1S6CT@1236|Gammaproteobacteria,4BV6Z@82986|Tatumella	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4156)	yjeI	GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716	-	-	-	-	-	-	-	-	-	-	DUF4156
REGS1_k127_5980745_3	502025.Hoch_6212	2.297e-05	56.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,NLPC_P60
REGS1_k127_5980745_1	1121918.ARWE01000001_gene1901	2.437e-66	238.0	COG0596@1|root,COG0596@2|Bacteria,1MVTG@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid	mhpC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0018771,GO:0019439,GO:0019622,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046164,GO:0046395,GO:0046435,GO:0052823,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616	2.3.1.12,3.7.1.14,3.7.1.8,3.7.1.9	ko:K00627,ko:K05714,ko:K10216,ko:K10222,ko:K10623	ko00010,ko00020,ko00360,ko00362,ko00620,ko00621,ko00622,ko00643,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00010,map00020,map00360,map00362,map00620,map00621,map00622,map00643,map01100,map01110,map01120,map01130,map01200,map01220	M00307,M00539,M00543,M00545,M00569	R00209,R02569,R02603,R02604,R02606,R05359,R05360,R05361,R05362,R05364,R05865,R06789	RC00004,RC00272,RC00475,RC00476,RC00752,RC00753,RC00754,RC00755,RC00757,RC01337,RC01339,RC01485,RC02742,RC02857	br01601,br01602,ko00000,ko00001,ko00002,ko01000	-	-	iECDH10B_1368.ECDH10B_1361	Abhydrolase_1
REGS1_k127_5980745_0	290397.Adeh_0008	1.128e-162	522.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2YUAI@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
REGS1_k127_5986799_1	404589.Anae109_2681	2.172e-42	165.0	2EKQ7@1|root,33EDZ@2|Bacteria,1NHK0@1224|Proteobacteria,42VJ3@68525|delta/epsilon subdivisions,2WRIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2845
REGS1_k127_5986799_0	404589.Anae109_0900	1.582e-247	776.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,2YX5W@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
REGS1_k127_5990974_13	398767.Glov_3451	3.201e-14	76.0	COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,42SWB@68525|delta/epsilon subdivisions,2WPMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_5990974_10	443143.GM18_2002	2.341e-44	181.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2X734@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_5990974_0	404589.Anae109_0350	5.528e-193	618.0	2AIV6@1|root,319CD@2|Bacteria,1Q2BD@1224|Proteobacteria,437XV@68525|delta/epsilon subdivisions,2X37S@28221|Deltaproteobacteria,2YUR7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5990974_8	404589.Anae109_0349	1.492e-65	226.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,2YVX9@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
REGS1_k127_5990974_1	404589.Anae109_0348	4.293e-158	526.0	COG1305@1|root,COG1305@2|Bacteria,1RARF@1224|Proteobacteria,42R14@68525|delta/epsilon subdivisions,2WN3R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM transglutaminase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
REGS1_k127_5990974_6	290397.Adeh_4076	2.185e-73	273.0	COG2715@1|root,COG2715@2|Bacteria,1QVA6@1224|Proteobacteria,42TBA@68525|delta/epsilon subdivisions,2WPCY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleoside recognition	-	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
REGS1_k127_5990974_4	404589.Anae109_0346	2.136e-75	269.0	COG0700@1|root,COG0700@2|Bacteria,1MVZ0@1224|Proteobacteria,430SU@68525|delta/epsilon subdivisions,2WVYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane protein required for spore maturation in B.subtilis	-	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_5990974_11	290397.Adeh_3148	3.62e-29	123.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_5990974_14	1278073.MYSTI_02658	1.975e-10	74.0	COG5662@1|root,COG5662@2|Bacteria,1PC2D@1224|Proteobacteria,4387M@68525|delta/epsilon subdivisions,2X3HF@28221|Deltaproteobacteria,2YW42@29|Myxococcales	28221|Deltaproteobacteria	K	AntiSigma factor	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
REGS1_k127_5990974_7	1242864.D187_001908	6.116e-70	263.0	COG4249@1|root,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Peptidase C14, caspase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,Peptidase_C14
REGS1_k127_5990974_2	404589.Anae109_0112	1.199e-122	408.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5990974_12	391625.PPSIR1_00837	1.165e-17	97.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
REGS1_k127_5990974_5	290397.Adeh_4078	2.629e-74	257.0	COG3884@1|root,COG3884@2|Bacteria,1NBT0@1224|Proteobacteria,42W3W@68525|delta/epsilon subdivisions,2WR9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
REGS1_k127_5990974_3	404589.Anae109_4190	3.582e-90	301.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,2YXED@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the aspartate-semialdehyde dehydrogenase family	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_6011702_2	765869.BDW_08695	7.127e-54	191.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,42PEB@68525|delta/epsilon subdivisions,2MTT5@213481|Bdellovibrionales,2WM0Y@28221|Deltaproteobacteria	213481|Bdellovibrionales	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	fbaB	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
REGS1_k127_6011702_1	404589.Anae109_2359	2.28e-193	613.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_6011702_0	404589.Anae109_2761	6.859e-203	637.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42PTC@68525|delta/epsilon subdivisions,2WM3S@28221|Deltaproteobacteria,2YTUU@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
REGS1_k127_6031168_0	404589.Anae109_2842	7.693e-50	185.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	PFAM OmpA MotB domain protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
REGS1_k127_6031168_1	562970.Btus_2226	1.499e-23	108.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,278K5@186823|Alicyclobacillaceae	91061|Bacilli	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_6031168_3	755731.Clo1100_0406	7.233e-05	49.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,36KEV@31979|Clostridiaceae	186801|Clostridia	S	PFAM Sporulation protein YtfJ	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
REGS1_k127_6031168_2	509191.AEDB02000003_gene1061	3.36e-13	78.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,3WK6G@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YtfJ	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
REGS1_k127_6033687_8	404589.Anae109_1861	2.529e-112	392.0	COG2067@1|root,COG2067@2|Bacteria,1MY5K@1224|Proteobacteria	1224|Proteobacteria	I	long-chain fatty acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
REGS1_k127_6033687_11	404589.Anae109_1859	2.248e-31	141.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CarbopepD_reg_2,CarboxypepD_reg,PD40
REGS1_k127_6033687_10	404589.Anae109_1856	4.621e-44	172.0	COG3712@1|root,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_19,TPR_8,TonB_dep_Rec
REGS1_k127_6033687_2	404589.Anae109_1855	2.579e-149	508.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,MASE3,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_6033687_0	404589.Anae109_1854	0.0	1300.0	COG2199@1|root,COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,COG5002@2|Bacteria,1R7HC@1224|Proteobacteria,43BX3@68525|delta/epsilon subdivisions,2X77W@28221|Deltaproteobacteria,2YUH7@29|Myxococcales	28221|Deltaproteobacteria	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HisKA,PAS,Response_reg
REGS1_k127_6033687_1	404589.Anae109_1853	0.0	1079.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2YU94@29|Myxococcales	28221|Deltaproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_6033687_3	404589.Anae109_1851	1.939e-130	420.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2YV8C@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
REGS1_k127_6033687_9	404589.Anae109_1849	2.644e-47	182.0	COG0642@1|root,COG2205@2|Bacteria	404589.Anae109_1849|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6033687_7	404589.Anae109_1848	2.077e-113	376.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_6033687_5	243231.GSU3217	7.108e-125	414.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria,43S25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_6033687_4	404589.Anae109_1846	4.409e-125	405.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42TFH@68525|delta/epsilon subdivisions,2WPEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_6034229_1	404589.Anae109_2968	4.155e-42	156.0	COG0366@1|root,COG0366@2|Bacteria,1MVKX@1224|Proteobacteria,42P6Z@68525|delta/epsilon subdivisions,2WK5W@28221|Deltaproteobacteria,2YUMK@29|Myxococcales	28221|Deltaproteobacteria	G	Maltogenic Amylase, C-terminal domain	treS	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
REGS1_k127_6034229_0	1242864.D187_009698	1.133e-100	349.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4389X@68525|delta/epsilon subdivisions,2X3J9@28221|Deltaproteobacteria,2YWB4@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,Response_reg
REGS1_k127_6034229_3	378806.STAUR_3894	2.23e-06	53.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	Gly-zipper_Omp,OmpA,TSP_3
REGS1_k127_6099635_0	290397.Adeh_0817	0.0	1486.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
REGS1_k127_6099635_1	404589.Anae109_0855	1.667e-264	863.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJZJ@28221|Deltaproteobacteria,2Z2XA@29|Myxococcales	28221|Deltaproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
REGS1_k127_6099635_16	1379270.AUXF01000002_gene1392	0.0001219	55.0	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
REGS1_k127_6099635_17	1123075.AUDP01000020_gene1534	0.0004887	53.0	COG1598@1|root,COG1598@2|Bacteria,1VAKM@1239|Firmicutes,24K5X@186801|Clostridia,3WKAK@541000|Ruminococcaceae	186801|Clostridia	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB_lk_antitox
REGS1_k127_6099635_15	1440052.EAKF1_ch2357	1.015e-15	81.0	COG1724@1|root,COG1724@2|Bacteria,1N7S3@1224|Proteobacteria,1SHY4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
REGS1_k127_6099635_8	1144275.COCOR_01383	5.557e-63	229.0	2ENGF@1|root,33G3Y@2|Bacteria,1P8WT@1224|Proteobacteria,43261@68525|delta/epsilon subdivisions,2WXJG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6099635_12	290397.Adeh_0219	7.778e-37	143.0	COG2703@1|root,COG2703@2|Bacteria,1N8CS@1224|Proteobacteria,42VDH@68525|delta/epsilon subdivisions,2WRTV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_6099635_10	384676.PSEEN0998	4.757e-52	188.0	COG0454@1|root,COG0456@2|Bacteria,1RIMQ@1224|Proteobacteria,1S6A2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_6099635_11	401526.TcarDRAFT_0025	1.65e-48	178.0	COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,4H4CB@909932|Negativicutes	909932|Negativicutes	P	Iron-storage protein	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
REGS1_k127_6099635_5	404589.Anae109_0191	7.642e-141	454.0	COG1163@1|root,COG1163@2|Bacteria,1RFPD@1224|Proteobacteria,42ZF3@68525|delta/epsilon subdivisions,2WUZY@28221|Deltaproteobacteria,2Z0K4@29|Myxococcales	28221|Deltaproteobacteria	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
REGS1_k127_6099635_7	290397.Adeh_3811	1.818e-91	308.0	COG1011@1|root,COG1011@2|Bacteria,1MVWN@1224|Proteobacteria,43DWE@68525|delta/epsilon subdivisions,2WZ1W@28221|Deltaproteobacteria,2Z153@29|Myxococcales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	3.8.1.2	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_6099635_6	204669.Acid345_0206	1.618e-103	360.0	COG2989@1|root,COG2989@2|Bacteria,3Y2YW@57723|Acidobacteria,2JIFK@204432|Acidobacteriia	2|Bacteria	S	ErfK YbiS YcfS YnhG family protein	ycbB	-	-	ko:K21470	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	PG_binding_1,YkuD
REGS1_k127_6099635_2	404589.Anae109_2977	4.573e-200	634.0	COG0793@1|root,COG0793@2|Bacteria,1MUA3@1224|Proteobacteria,43413@68525|delta/epsilon subdivisions,2X4K3@28221|Deltaproteobacteria,2YZ68@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family S41	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_S41
REGS1_k127_6099635_9	640081.Dsui_0685	1.049e-62	239.0	COG0625@1|root,COG0625@2|Bacteria,1PHM1@1224|Proteobacteria,2VI65@28216|Betaproteobacteria,2KW9Y@206389|Rhodocyclales	206389|Rhodocyclales	O	Glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_2,GST_N_3
REGS1_k127_6099635_3	404589.Anae109_0858	1.507e-175	563.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42PMA@68525|delta/epsilon subdivisions,2X5AR@28221|Deltaproteobacteria,2Z0NV@29|Myxococcales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
REGS1_k127_6099635_4	1254432.SCE1572_23580	2.235e-153	502.0	COG1360@1|root,COG1360@2|Bacteria,1R0CK@1224|Proteobacteria,43CV5@68525|delta/epsilon subdivisions,2X830@28221|Deltaproteobacteria,2Z3JV@29|Myxococcales	28221|Deltaproteobacteria	N	Flagellar Motor Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6106060_3	404589.Anae109_1310	9.385e-34	148.0	COG0011@1|root,COG0011@2|Bacteria,1NDDR@1224|Proteobacteria,42VMM@68525|delta/epsilon subdivisions,2X6N6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
REGS1_k127_6106060_1	290397.Adeh_2551	5.621e-102	346.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA
REGS1_k127_6106060_0	404589.Anae109_1311	0.0	1116.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2YUFJ@29|Myxococcales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
REGS1_k127_6106060_2	404589.Anae109_1312	2.386e-47	172.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,42TSD@68525|delta/epsilon subdivisions,2WQ6E@28221|Deltaproteobacteria,2YVDZ@29|Myxococcales	28221|Deltaproteobacteria	J	endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
REGS1_k127_6114109_1	399739.Pmen_2799	2.849e-31	130.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,1S294@1236|Gammaproteobacteria,1YD39@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	N	Homologous to MotB. These organism have both MotB and MotD. With MotC (a MotA homolog) forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. Either MotAB or MotCD is sufficient for swimming, but both are necessary for swarming motility	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
REGS1_k127_6114109_0	562970.Btus_2182	2.603e-36	147.0	COG1360@1|root,COG1360@2|Bacteria,1UXY4@1239|Firmicutes,4HCCI@91061|Bacilli,27AQU@186823|Alicyclobacillaceae	91061|Bacilli	N	Membrane MotB of proton-channel complex MotA/MotB	ytxE	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotB_plug,OmpA
REGS1_k127_6114109_2	865861.AZSU01000003_gene1692	1.583e-24	106.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia,36E57@31979|Clostridiaceae	186801|Clostridia	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
REGS1_k127_6123159_1	290397.Adeh_0736	4.892e-171	541.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2YU97@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
REGS1_k127_6123159_2	290397.Adeh_0734	9.495e-148	473.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,2YWSU@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_6123159_3	290397.Adeh_0733	1.606e-107	358.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
REGS1_k127_6123159_0	404589.Anae109_0776	9.097e-245	776.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2YTSW@29|Myxococcales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
REGS1_k127_6123159_4	909663.KI867150_gene1952	1.799e-20	94.0	COG0745@1|root,COG0745@2|Bacteria,1RIN6@1224|Proteobacteria,42T2W@68525|delta/epsilon subdivisions,2WPU9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
REGS1_k127_6138141_1	404589.Anae109_0536	5.04e-17	85.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
REGS1_k127_6138141_0	404589.Anae109_0535	3.461e-136	464.0	COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,42WF9@68525|delta/epsilon subdivisions,2WRD4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Outer membrane usher protein	csuD	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	Usher
REGS1_k127_6147384_3	404589.Anae109_1846	8.505e-34	135.0	COG4191@1|root,COG4191@2|Bacteria,1R5Q1@1224|Proteobacteria,42TFH@68525|delta/epsilon subdivisions,2WPEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_6147384_1	589865.DaAHT2_0397	8.005e-60	233.0	COG3005@1|root,COG3005@2|Bacteria,1QYGG@1224|Proteobacteria,42NFU@68525|delta/epsilon subdivisions,2WKHN@28221|Deltaproteobacteria,2MP53@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM doubled CXXCH domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_6147384_7	1121920.AUAU01000024_gene2376	8.745e-17	95.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	-	-	5.2.1.8	ko:K03769,ko:K03770,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N_3
REGS1_k127_6147384_5	243231.GSU1788	1.444e-20	104.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_6147384_0	1167006.UWK_00566	3.434e-92	326.0	COG3303@1|root,COG3303@2|Bacteria,1PEVM@1224|Proteobacteria,42YEH@68525|delta/epsilon subdivisions,2WU0R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_6147384_4	1121920.AUAU01000024_gene2380	1.301e-29	132.0	COG3391@1|root,COG3391@2|Bacteria,3Y8A0@57723|Acidobacteria	57723|Acidobacteria	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_6147384_6	1121918.ARWE01000001_gene832	1.154e-17	91.0	COG3303@1|root,COG3303@2|Bacteria,1NX4E@1224|Proteobacteria	1224|Proteobacteria	P	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_6147384_8	204669.Acid345_3128	1.51e-14	81.0	COG1287@1|root,COG1287@2|Bacteria,3Y5FJ@57723|Acidobacteria,2JJV3@204432|Acidobacteriia	204432|Acidobacteriia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6153236_2	1379270.AUXF01000006_gene28	1.764e-19	97.0	2FH8C@1|root,3492Q@2|Bacteria,1ZTXE@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Domain of unknown function (DUF4321)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4321
REGS1_k127_6153236_0	379066.GAU_1932	1.874e-115	381.0	COG0142@1|root,COG0142@2|Bacteria,1ZT7D@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_6153236_1	1379270.AUXF01000006_gene26	7.529e-80	279.0	COG0457@1|root,COG0457@2|Bacteria,1ZU0J@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_8
REGS1_k127_6158941_5	290397.Adeh_0988	1.083e-26	127.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria,2Z1Q1@29|Myxococcales	28221|Deltaproteobacteria	K	Cold-shock protein	cspE	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_6158941_4	404589.Anae109_0422	3.007e-104	342.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2Z2Z8@29|Myxococcales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
REGS1_k127_6158941_2	290397.Adeh_4003	9.941e-124	417.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,2YUBB@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
REGS1_k127_6158941_1	404589.Anae109_0420	1.408e-135	454.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WJKH@28221|Deltaproteobacteria,2YVAR@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,DUF3333
REGS1_k127_6158941_0	290397.Adeh_4005	3.354e-142	463.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WJJ1@28221|Deltaproteobacteria,2YV6J@29|Myxococcales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
REGS1_k127_6158941_3	404589.Anae109_0418	3.872e-105	359.0	COG0226@1|root,COG0226@2|Bacteria,1MVXP@1224|Proteobacteria,42P0G@68525|delta/epsilon subdivisions,2WK7Y@28221|Deltaproteobacteria,2YVQ5@29|Myxococcales	28221|Deltaproteobacteria	P	PBP superfamily domain	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_6158941_6	596154.Alide2_4183	2.69e-22	102.0	COG1871@1|root,COG1871@2|Bacteria,1RDDB@1224|Proteobacteria,2VJ1T@28216|Betaproteobacteria,4AC78@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
REGS1_k127_6160134_6	653045.Strvi_5234	1.305e-34	149.0	COG1926@1|root,COG2312@1|root,COG1926@2|Bacteria,COG2312@2|Bacteria,2GJUU@201174|Actinobacteria	201174|Actinobacteria	Q	phosphoribosyltransferase	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	Erythro_esteras,Pribosyltran
REGS1_k127_6160134_3	404589.Anae109_2956	2.792e-98	327.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42R3E@68525|delta/epsilon subdivisions,2WN3C@28221|Deltaproteobacteria,2Z350@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
REGS1_k127_6160134_4	290397.Adeh_2989	5.329e-72	249.0	2E0UW@1|root,32WC8@2|Bacteria,1P2M6@1224|Proteobacteria,431CM@68525|delta/epsilon subdivisions,2WW9V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_6160134_2	290397.Adeh_2987	1.77e-98	328.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_6160134_0	290397.Adeh_2958	1.476e-172	554.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
REGS1_k127_6160134_1	404589.Anae109_2819	6.709e-141	456.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions,2WKAC@28221|Deltaproteobacteria,2YYQW@29|Myxococcales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES domain protein	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_6160134_5	153948.NAL212_0221	1.268e-53	212.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,2VZPE@28216|Betaproteobacteria,374NZ@32003|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM Peptidase S8 S53, subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	CARDB,Peptidase_S8
REGS1_k127_6160518_7	1121920.AUAU01000022_gene2462	8.7e-58	220.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K02660,ko:K11525	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,EAL,GAF,GGDEF,HAMP,MCPsignal,PAS_3,PAS_4,PAS_7,dCache_1
REGS1_k127_6160518_10	290397.Adeh_0671	2.826e-30	134.0	COG1670@1|root,COG1670@2|Bacteria,1NNMC@1224|Proteobacteria,43B06@68525|delta/epsilon subdivisions,2X6EA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6160518_6	290397.Adeh_0672	7.461e-78	286.0	COG0546@1|root,COG0546@2|Bacteria,1P1EG@1224|Proteobacteria,431YQ@68525|delta/epsilon subdivisions,2WWM2@28221|Deltaproteobacteria,2Z34R@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
REGS1_k127_6160518_3	404589.Anae109_0718	6e-168	540.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,2YY2A@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
REGS1_k127_6160518_9	207559.Dde_1892	1.169e-39	155.0	COG1309@1|root,COG1309@2|Bacteria,1NM93@1224|Proteobacteria,42V53@68525|delta/epsilon subdivisions,2WRUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_6160518_12	240292.Ava_3671	1.196e-19	98.0	COG0546@1|root,COG0546@2|Bacteria,1GQDN@1117|Cyanobacteria,1HNNX@1161|Nostocales	1117|Cyanobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6160518_0	290397.Adeh_0674	0.0	1799.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2YU45@29|Myxococcales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
REGS1_k127_6160518_1	290397.Adeh_0675	1.009e-216	699.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	-	-	-	-	-	-	-	-	-	-	-	-	MCPsignal
REGS1_k127_6160518_5	744872.Spica_0369	4.828e-85	295.0	COG1373@1|root,COG1373@2|Bacteria,2J5MK@203691|Spirochaetes	203691|Spirochaetes	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
REGS1_k127_6160518_4	404589.Anae109_0720	6.634e-91	310.0	2DRH1@1|root,33BQ8@2|Bacteria,1NM8D@1224|Proteobacteria,42XND@68525|delta/epsilon subdivisions,2WSKN@28221|Deltaproteobacteria,2YW71@29|Myxococcales	28221|Deltaproteobacteria	-	-	gspN	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
REGS1_k127_6160518_8	404589.Anae109_0721	4.703e-49	198.0	COG3149@1|root,COG3149@2|Bacteria,1NEZ3@1224|Proteobacteria,42WMP@68525|delta/epsilon subdivisions,2WSE1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein M	-	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
REGS1_k127_6160518_2	404589.Anae109_0722	9.475e-206	653.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2YVKD@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
REGS1_k127_6160518_13	404589.Anae109_0723	9.34e-06	48.0	COG3156@1|root,COG3156@2|Bacteria,1RIW9@1224|Proteobacteria,42V6H@68525|delta/epsilon subdivisions,2X2BW@28221|Deltaproteobacteria,2YVV7@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
REGS1_k127_6182509_0	404589.Anae109_2790	1.574e-90	310.0	COG1301@1|root,COG1301@2|Bacteria,1MU0Q@1224|Proteobacteria,42MZ6@68525|delta/epsilon subdivisions,2WJXZ@28221|Deltaproteobacteria,2YUTQ@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	gltP	-	-	ko:K03309	-	-	-	-	ko00000	2.A.23	-	-	SDF
REGS1_k127_6182509_3	697282.Mettu_1402	3.697e-06	53.0	2EKK5@1|root,33EA0@2|Bacteria,1NI6Y@1224|Proteobacteria,1SGCX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
REGS1_k127_6182509_2	1144275.COCOR_00140	1.331e-23	103.0	COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,42V73@68525|delta/epsilon subdivisions,2WSD3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_6182509_1	485918.Cpin_2204	3.87e-29	119.0	2E5B7@1|root,3303B@2|Bacteria,4NVGK@976|Bacteroidetes,1J01Q@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6188829_2	404589.Anae109_1823	5.68e-39	168.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
REGS1_k127_6188829_0	443144.GM21_3550	1.246e-82	312.0	COG0577@1|root,COG0577@2|Bacteria,1PU2M@1224|Proteobacteria,43AD5@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_6188829_3	1122947.FR7_2275	2.156e-35	156.0	COG0577@1|root,COG0577@2|Bacteria,1TUYK@1239|Firmicutes,4H21N@909932|Negativicutes	909932|Negativicutes	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_6188829_1	443143.GM18_0603	1.226e-68	242.0	COG1136@1|root,COG1136@2|Bacteria,1Q3QX@1224|Proteobacteria,42NVX@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_6188829_4	246197.MXAN_3423	2.014e-11	76.0	COG4633@1|root,COG4633@2|Bacteria,1N1UQ@1224|Proteobacteria,4352K@68525|delta/epsilon subdivisions,2WZDN@28221|Deltaproteobacteria,2Z1WQ@29|Myxococcales	28221|Deltaproteobacteria	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
REGS1_k127_6205738_2	1197906.CAJQ02000027_gene1525	7.199e-06	51.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3JV1X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Recombinase zinc beta ribbon domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
REGS1_k127_6205738_1	1168059.KB899087_gene1061	2.774e-06	52.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,2TRIY@28211|Alphaproteobacteria,3F0VP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
REGS1_k127_6205738_0	404589.Anae109_3978	1.118e-251	780.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2YWV6@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
REGS1_k127_6208198_1	290397.Adeh_0279	1.331e-198	634.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,2YU8X@29|Myxococcales	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
REGS1_k127_6208198_5	290397.Adeh_0278	1.31e-95	320.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,42REG@68525|delta/epsilon subdivisions,2WNK2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF208,RNase_HII
REGS1_k127_6208198_16	269799.Gmet_0139	1.905e-10	72.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase,YadA_stalk
REGS1_k127_6208198_14	269799.Gmet_3250	1.899e-24	113.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
REGS1_k127_6208198_11	1239962.C943_02197	1.127e-29	126.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
REGS1_k127_6208198_0	404589.Anae109_0298	2.644e-203	640.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria	1224|Proteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	sun1	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
REGS1_k127_6208198_9	1297742.A176_01698	3.825e-35	136.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,2YV5F@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_6208198_15	1250278.JQNQ01000001_gene3543	1.245e-11	66.0	COG1225@1|root,COG1225@2|Bacteria,4NNGK@976|Bacteroidetes,1I16V@117743|Flavobacteriia	976|Bacteroidetes	O	Thiol peroxidase	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_6208198_12	555088.DealDRAFT_2507	8.755e-27	113.0	COG2146@1|root,COG2146@2|Bacteria,1VF0R@1239|Firmicutes,24UDZ@186801|Clostridia	186801|Clostridia	P	PFAM Rieske 2Fe-2S domain	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
REGS1_k127_6208198_13	386456.JQKN01000004_gene202	1.222e-26	110.0	COG0695@1|root,arCOG02606@2157|Archaea,2Y0FK@28890|Euryarchaeota	28890|Euryarchaeota	O	Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
REGS1_k127_6208198_7	304371.MCP_0977	8.833e-44	163.0	COG4802@1|root,arCOG01099@2157|Archaea,2Y47M@28890|Euryarchaeota,2NB0P@224756|Methanomicrobia	224756|Methanomicrobia	C	Ferredoxin thioredoxin reductase catalytic beta chain	-	-	-	-	-	-	-	-	-	-	-	-	FeThRed_B
REGS1_k127_6208198_10	351160.RRC297	1.045e-29	123.0	COG2146@1|root,arCOG02854@2157|Archaea	2157|Archaea	C	PFAM Rieske 2Fe-2S domain	sdx	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	DAO,Rieske
REGS1_k127_6208198_6	1502851.FG93_03435	5.378e-83	279.0	COG3631@1|root,COG3631@2|Bacteria,1RGEA@1224|Proteobacteria,2U7YB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
REGS1_k127_6208198_3	290397.Adeh_0274	1.498e-117	389.0	COG4469@1|root,COG4469@2|Bacteria	2|Bacteria	-	-	coiA	-	-	ko:K06198	-	-	-	-	ko00000	-	-	-	CoiA
REGS1_k127_6208198_2	404589.Anae109_0295	1.883e-162	519.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2YTZQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
REGS1_k127_6208198_4	290397.Adeh_0272	9.455e-101	333.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2YVCJ@29|Myxococcales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
REGS1_k127_623687_6	545276.KB898731_gene2145	4.118e-12	71.0	COG1669@1|root,COG1669@2|Bacteria,1NMHI@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
REGS1_k127_623687_0	404589.Anae109_2525	1.938e-260	833.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria,2YUNJ@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
REGS1_k127_623687_1	290397.Adeh_1243	2.932e-229	718.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria,2YYEJ@29|Myxococcales	28221|Deltaproteobacteria	F	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
REGS1_k127_623687_5	404589.Anae109_2523	1.143e-55	197.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,2Z1I1@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
REGS1_k127_623687_2	404589.Anae109_2522	1.302e-169	559.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WK2P@28221|Deltaproteobacteria,2YU3I@29|Myxococcales	28221|Deltaproteobacteria	H	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
REGS1_k127_623687_4	290397.Adeh_1246	1.746e-102	357.0	COG1409@1|root,COG1409@2|Bacteria,1PCIF@1224|Proteobacteria,438G6@68525|delta/epsilon subdivisions,2X3R2@28221|Deltaproteobacteria,2YWW5@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
REGS1_k127_623687_3	398767.Glov_0508	2.372e-103	341.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,43UKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1162	THF_DHG_CYH,THF_DHG_CYH_C
REGS1_k127_6298841_2	1192034.CAP_1358	3.445e-44	182.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
REGS1_k127_6298841_0	118168.MC7420_2619	6.662e-169	543.0	COG0579@1|root,COG0579@2|Bacteria,1G0XV@1117|Cyanobacteria,1HA8I@1150|Oscillatoriales	1117|Cyanobacteria	C	BFD-like [2Fe-2S] binding domain	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
REGS1_k127_6298841_1	926692.AZYG01000064_gene953	2.262e-123	408.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia	186801|Clostridia	C	pyridine nucleotide-disulfide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
REGS1_k127_6298841_3	1280686.AUKE01000008_gene2700	8.32e-24	117.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,4BZDQ@830|Butyrivibrio	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
REGS1_k127_6310701_2	159087.Daro_4005	7.594e-97	319.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2VIRF@28216|Betaproteobacteria,2KVDF@206389|Rhodocyclales	206389|Rhodocyclales	E	periplasmic protein kinase ArgK and related GTPases of G3E family	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
REGS1_k127_6310701_1	290397.Adeh_0260	1.224e-162	530.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_16
REGS1_k127_6310701_3	404589.Anae109_0283	3.239e-35	156.0	COG1534@1|root,COG1534@2|Bacteria,1Q1JA@1224|Proteobacteria,42W6U@68525|delta/epsilon subdivisions,2WQS8@28221|Deltaproteobacteria,2YVUX@29|Myxococcales	28221|Deltaproteobacteria	J	CRS1_YhbY	-	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
REGS1_k127_6310701_0	290397.Adeh_1665	4.868e-195	613.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria,2YXAE@29|Myxococcales	28221|Deltaproteobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_6330057_3	765913.ThidrDRAFT_4577	9.018e-13	70.0	COG3385@1|root,COG5433@1|root,COG3385@2|Bacteria,COG5433@2|Bacteria,1MXB5@1224|Proteobacteria,1RSAV@1236|Gammaproteobacteria,1WWWX@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_assoc
REGS1_k127_6330057_0	404589.Anae109_3700	6.42e-114	376.0	COG1090@1|root,COG1090@2|Bacteria,1MUB4@1224|Proteobacteria,42QUU@68525|delta/epsilon subdivisions,2WKRY@28221|Deltaproteobacteria,2YUWB@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
REGS1_k127_6330057_1	1384054.N790_09605	1.696e-73	267.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria,1XA50@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
REGS1_k127_6330057_2	1384054.N790_09610	5.606e-52	201.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the peptidase S11 family	pbpG	-	3.4.16.4	ko:K07258,ko:K07262	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
REGS1_k127_6330776_3	404589.Anae109_0412	1.564e-94	314.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,2YX4E@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
REGS1_k127_6330776_4	404589.Anae109_0414	5.013e-86	297.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	uptE	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
REGS1_k127_6330776_2	290397.Adeh_4009	1.407e-95	344.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2YURD@29|Myxococcales	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_6330776_1	290397.Adeh_4008	8.301e-152	488.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,2YY2P@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
REGS1_k127_6330776_0	290397.Adeh_2061	7.196e-239	763.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YU05@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
REGS1_k127_633241_1	215803.DB30_4591	1.175e-09	63.0	COG5009@1|root,COG5009@2|Bacteria,1P2NY@1224|Proteobacteria,431XY@68525|delta/epsilon subdivisions,2WW86@28221|Deltaproteobacteria,2YYSF@29|Myxococcales	28221|Deltaproteobacteria	M	serine-type D-Ala-D-Ala carboxypeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_633241_0	1242864.D187_009860	0.0	1301.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WU7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,Thiol-ester_cl
REGS1_k127_6435134_5	290397.Adeh_0169	1.887e-63	226.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_0169|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6435134_2	290397.Adeh_0172	2.512e-134	432.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,2YUS2@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
REGS1_k127_6435134_11	404589.Anae109_2405	1.042e-07	59.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	ccoP	-	-	ko:K00406,ko:K08906	ko00190,ko00195,ko01100,ko02020,map00190,map00195,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002,ko00194	3.D.4.3	-	-	Cytochrome_CBB3,FixP_N
REGS1_k127_6435134_10	565045.NOR51B_1342	1.816e-10	74.0	COG2010@1|root,COG2374@1|root,COG3391@1|root,COG2010@2|Bacteria,COG2374@2|Bacteria,COG3391@2|Bacteria,1QWRQ@1224|Proteobacteria	1224|Proteobacteria	M	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Abhydrolase_3,Cadherin-like,Cadherin_3,TIG,VCBS
REGS1_k127_6435134_8	1499967.BAYZ01000016_gene6497	9.356e-42	167.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_6435134_9	290397.Adeh_0728	8.987e-36	143.0	2DVJC@1|root,33W5M@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6435134_4	290397.Adeh_0179	3.101e-66	229.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,2YVDP@29|Myxococcales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
REGS1_k127_6435134_7	404589.Anae109_0197	2.131e-43	175.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WPB9@28221|Deltaproteobacteria,2Z2ZN@29|Myxococcales	28221|Deltaproteobacteria	FG	HIT domain	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
REGS1_k127_6435134_3	414684.RC1_3930	1.854e-110	370.0	COG2301@1|root,COG2301@2|Bacteria,1MW0A@1224|Proteobacteria,2TTC0@28211|Alphaproteobacteria,2JQKY@204441|Rhodospirillales	204441|Rhodospirillales	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
REGS1_k127_6435134_1	404589.Anae109_2939	3.281e-229	721.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_6435134_0	404589.Anae109_4390	2.939e-287	892.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
REGS1_k127_6444974_2	290397.Adeh_1677	6.554e-17	81.0	COG1055@1|root,COG1055@2|Bacteria,1NEVR@1224|Proteobacteria,42NU5@68525|delta/epsilon subdivisions,2WJV4@28221|Deltaproteobacteria,2YX9Q@29|Myxococcales	28221|Deltaproteobacteria	P	Arsenical pump membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
REGS1_k127_6444974_1	314278.NB231_14608	1.033e-19	98.0	COG3637@1|root,COG3637@2|Bacteria,1RHUP@1224|Proteobacteria	1224|Proteobacteria	M	Domain of unknown function (DUF3943)	VP1938	-	-	-	-	-	-	-	-	-	-	-	DUF3943,OMP_b-brl
REGS1_k127_6444974_0	290397.Adeh_0401	8.947e-130	420.0	COG1234@1|root,COG1234@2|Bacteria,1Q4PW@1224|Proteobacteria,42VTH@68525|delta/epsilon subdivisions,2WS84@28221|Deltaproteobacteria,2YYDW@29|Myxococcales	28221|Deltaproteobacteria	J	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
REGS1_k127_6450469_0	1304883.KI912532_gene1016	2.761e-105	347.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VIT2@28216|Betaproteobacteria,2KV3E@206389|Rhodocyclales	206389|Rhodocyclales	I	Methylmalonyl-CoA mutase	mutB	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
REGS1_k127_6450469_1	404589.Anae109_0276	1.25e-92	310.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42QIX@68525|delta/epsilon subdivisions,2WJHE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_6450469_2	404589.Anae109_0274	8.958e-78	264.0	COG2070@1|root,COG2070@2|Bacteria,1MWPC@1224|Proteobacteria,43AEV@68525|delta/epsilon subdivisions,2X5YA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	2-nitropropane dioxygenase	-	-	1.13.12.16,1.3.1.9	ko:K00459,ko:K02371	ko00061,ko00910,ko01100,ko01212,map00061,map00910,map01100,map01212	M00083	R00025,R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076,RC02541,RC02759	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO
REGS1_k127_6476016_1	404589.Anae109_0271	5.112e-19	87.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,2YU6I@29|Myxococcales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	pccB	-	2.1.3.1,2.1.3.15,6.4.1.3	ko:K01966,ko:K17489	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R00353,R01859	RC00040,RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
REGS1_k127_6476016_0	404589.Anae109_0270	1.185e-119	402.0	COG1413@1|root,COG1413@2|Bacteria,1QX4H@1224|Proteobacteria,42Z02@68525|delta/epsilon subdivisions,2WUJ9@28221|Deltaproteobacteria,2YVP1@29|Myxococcales	28221|Deltaproteobacteria	C	Type II secretion system (T2SS), protein E, N-terminal domain	frgA	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,T2SSE_N
REGS1_k127_6477105_1	404589.Anae109_3943	6.154e-26	107.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,42SPQ@68525|delta/epsilon subdivisions,2WPX1@28221|Deltaproteobacteria,2YWQX@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
REGS1_k127_6477105_0	290397.Adeh_3828	2.578e-165	527.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,42MY5@68525|delta/epsilon subdivisions,2WKST@28221|Deltaproteobacteria,2YUHP@29|Myxococcales	28221|Deltaproteobacteria	E	succinyl-diaminopimelate desuccinylase	dapE2	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
REGS1_k127_6530848_4	644282.Deba_0681	1.234e-32	128.0	COG3829@1|root,COG3829@2|Bacteria,1QW3X@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	2.1.1.80,2.7.13.3,3.1.1.61	ko:K03406,ko:K13924,ko:K14986	ko02020,ko02030,map02020,map02030	M00506,M00524	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheR,CheR_N,MCPsignal,PAS,PAS_3,PAS_4,PAS_9
REGS1_k127_6530848_1	290397.Adeh_0670	8.129e-246	767.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
REGS1_k127_6530848_2	404589.Anae109_0713	2.44e-156	503.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2YZGM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
REGS1_k127_6530848_5	1298858.AUEL01000018_gene3005	4.31e-17	91.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,43GWB@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
REGS1_k127_6530848_3	404589.Anae109_2389	6.466e-44	181.0	COG1877@1|root,COG1877@2|Bacteria,1Q1R2@1224|Proteobacteria,42U7I@68525|delta/epsilon subdivisions,2WQZE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	-	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
REGS1_k127_6530848_0	404589.Anae109_2390	3.264e-284	883.0	COG0380@1|root,COG0380@2|Bacteria,1MUIY@1224|Proteobacteria,42NBU@68525|delta/epsilon subdivisions,2WJX9@28221|Deltaproteobacteria,2YU3V@29|Myxococcales	28221|Deltaproteobacteria	G	glycosyl transferase family	-	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
REGS1_k127_6545606_1	1301098.PKB_3522	1.434e-30	123.0	COG1305@1|root,COG1305@2|Bacteria,1R9XR@1224|Proteobacteria,1S4S3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Cysteine	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
REGS1_k127_6545606_0	670292.JH26_06295	1.04e-275	864.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2TS8E@28211|Alphaproteobacteria,1JSMW@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM Enoyl-CoA hydratase isomerase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
REGS1_k127_6558540_11	404589.Anae109_1432	6.955e-29	119.0	COG0151@1|root,COG0151@2|Bacteria,1NA76@1224|Proteobacteria,43CA7@68525|delta/epsilon subdivisions,2X7KS@28221|Deltaproteobacteria,2Z204@29|Myxococcales	28221|Deltaproteobacteria	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
REGS1_k127_6558540_8	404589.Anae109_1417	1.433e-57	205.0	COG1714@1|root,COG1714@2|Bacteria,1NJXQ@1224|Proteobacteria,42XN4@68525|delta/epsilon subdivisions,2WSKW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
REGS1_k127_6558540_2	404589.Anae109_1415	3.134e-198	621.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,2YTTT@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
REGS1_k127_6558540_1	404589.Anae109_1414	7.389e-203	639.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42NTB@68525|delta/epsilon subdivisions,2WKNX@28221|Deltaproteobacteria,2Z31V@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
REGS1_k127_6558540_7	290397.Adeh_2454	2.114e-66	232.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42UBZ@68525|delta/epsilon subdivisions,2WQ0E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
REGS1_k127_6558540_4	404589.Anae109_4195	3.925e-132	432.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
REGS1_k127_6558540_5	290397.Adeh_2465	2.788e-130	425.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
REGS1_k127_6558540_6	404589.Anae109_1401	1.645e-75	260.0	COG0041@1|root,COG0041@2|Bacteria,1RCWJ@1224|Proteobacteria,42QTK@68525|delta/epsilon subdivisions,2WPG2@28221|Deltaproteobacteria,2Z2Z7@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
REGS1_k127_6558540_3	290397.Adeh_2467	3.084e-196	619.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2YU6X@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
REGS1_k127_6558540_12	290397.Adeh_0425	9.878e-08	65.0	COG0457@1|root,COG0457@2|Bacteria,1RJUD@1224|Proteobacteria,42P27@68525|delta/epsilon subdivisions,2WK9Y@28221|Deltaproteobacteria,2Z2Z5@29|Myxococcales	28221|Deltaproteobacteria	PT	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_8,TonB_dep_Rec,zinc_ribbon_4
REGS1_k127_6558540_0	290397.Adeh_2468	3.131e-296	914.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2YTYA@29|Myxococcales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
REGS1_k127_6558540_10	1123508.JH636441_gene3281	9.514e-49	187.0	COG1196@1|root,COG1196@2|Bacteria,2J4NQ@203682|Planctomycetes	203682|Planctomycetes	D	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
REGS1_k127_6580466_1	404589.Anae109_2646	1.843e-152	492.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Pyr_redox_3
REGS1_k127_6580466_0	290397.Adeh_2666	3.072e-243	781.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	28221|Deltaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_6580466_2	404589.Anae109_2645	1.616e-76	282.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	28221|Deltaproteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_6638148_4	880071.Fleli_2125	8.429e-15	86.0	COG2931@1|root,COG2931@2|Bacteria,4NU1P@976|Bacteroidetes,47XBG@768503|Cytophagia	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
REGS1_k127_6638148_2	1242864.D187_010496	1.01e-36	156.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_6638148_0	215803.DB30_6047	5.021e-87	311.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,2YYW2@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
REGS1_k127_6638148_1	246197.MXAN_1921	2.797e-68	256.0	COG0457@1|root,COG0457@2|Bacteria,1PDTX@1224|Proteobacteria,42RK5@68525|delta/epsilon subdivisions,2WNZC@28221|Deltaproteobacteria,2YW1B@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
REGS1_k127_6666751_0	246197.MXAN_5587	1.275e-62	228.0	2AK94@1|root,31AZD@2|Bacteria,1Q6KJ@1224|Proteobacteria,439D5@68525|delta/epsilon subdivisions,2X4MU@28221|Deltaproteobacteria,2YZ9M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6666751_1	215803.DB30_7093	2.226e-23	110.0	2BR1I@1|root,32JZ2@2|Bacteria,1Q2J5@1224|Proteobacteria,43863@68525|delta/epsilon subdivisions,2X3FX@28221|Deltaproteobacteria,2YVXD@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6694684_4	290397.Adeh_1643	2.379e-136	436.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJEI@28221|Deltaproteobacteria,2Z2X3@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
REGS1_k127_6694684_5	404589.Anae109_1990	2.386e-120	409.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2WK0F@28221|Deltaproteobacteria,2YUYV@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
REGS1_k127_6694684_2	404589.Anae109_1991	9.137e-153	500.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,2Z2WK@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
REGS1_k127_6694684_6	290397.Adeh_1828	3.017e-105	366.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria,2YUQJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
REGS1_k127_6694684_7	1144275.COCOR_02085	4.926e-73	270.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WM9S@28221|Deltaproteobacteria,2YZVS@29|Myxococcales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
REGS1_k127_6694684_1	290397.Adeh_1822	1.205e-184	593.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_6694684_3	290397.Adeh_1821	2.392e-139	466.0	COG0321@1|root,COG1051@1|root,COG0321@2|Bacteria,COG1051@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WNRX@28221|Deltaproteobacteria,2Z30D@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
REGS1_k127_6694684_0	290397.Adeh_1815	9.365e-232	724.0	COG0527@1|root,COG0527@2|Bacteria,1MVSI@1224|Proteobacteria,42NCA@68525|delta/epsilon subdivisions,2WIVC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aspartate glutamate uridylate kinase	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT_7
REGS1_k127_6694684_8	404589.Anae109_2014	1.436e-36	143.0	COG1555@1|root,COG1555@2|Bacteria,1Q1N7@1224|Proteobacteria,431JQ@68525|delta/epsilon subdivisions,2WT0M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Helix-hairpin-helix motif	-	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
REGS1_k127_6699164_3	1121430.JMLG01000005_gene758	9.652e-198	638.0	COG1543@1|root,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,248UF@186801|Clostridia,25ZYE@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
REGS1_k127_6699164_6	404380.Gbem_0567	7.561e-148	482.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
REGS1_k127_6699164_2	404589.Anae109_2446	4.066e-204	647.0	COG3170@1|root,COG3481@1|root,COG3170@2|Bacteria,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
REGS1_k127_6699164_13	290397.Adeh_1318	3.866e-95	316.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,42TFN@68525|delta/epsilon subdivisions,2WNCD@28221|Deltaproteobacteria,2Z1HN@29|Myxococcales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
REGS1_k127_6699164_11	404589.Anae109_2081	4.411e-101	349.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2X3AE@28221|Deltaproteobacteria,2YV4E@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
REGS1_k127_6699164_1	290397.Adeh_3831	1.978e-218	698.0	COG1249@1|root,COG1249@2|Bacteria,1MVVE@1224|Proteobacteria,42Z7G@68525|delta/epsilon subdivisions,2WU0D@28221|Deltaproteobacteria,2YU48@29|Myxococcales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	sthA	-	1.6.1.1	ko:K00322	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_6699164_18	290397.Adeh_1319	4.762e-64	233.0	COG2135@1|root,COG2135@2|Bacteria,1RER4@1224|Proteobacteria,42RQJ@68525|delta/epsilon subdivisions,2WNW8@28221|Deltaproteobacteria,2YVCK@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
REGS1_k127_6699164_14	290397.Adeh_1325	6.551e-86	308.0	COG2896@1|root,COG2896@2|Bacteria,1QYFW@1224|Proteobacteria,4315C@68525|delta/epsilon subdivisions,2WX3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
REGS1_k127_6699164_0	290397.Adeh_1326	3.283e-254	790.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_6699164_10	404589.Anae109_2440	1.143e-108	363.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,2YV02@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
REGS1_k127_6699164_16	290397.Adeh_1331	6.067e-69	236.0	COG0589@1|root,COG0589@2|Bacteria,1PDTQ@1224|Proteobacteria,42T4W@68525|delta/epsilon subdivisions,2WP70@28221|Deltaproteobacteria,2Z28U@29|Myxococcales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_6699164_22	404589.Anae109_2435	1.841e-14	81.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_6699164_9	290397.Adeh_1333	2.14e-117	379.0	COG0664@1|root,COG0664@2|Bacteria,1QAZ0@1224|Proteobacteria,43E4R@68525|delta/epsilon subdivisions,2WZQH@28221|Deltaproteobacteria,2Z2IM@29|Myxococcales	28221|Deltaproteobacteria	K	Crp-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_6699164_7	404589.Anae109_2433	2.927e-132	432.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42M5U@68525|delta/epsilon subdivisions,2WJ06@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	MoeA domain protein domain I and II	-	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
REGS1_k127_6699164_20	404589.Anae109_2432	4.554e-52	188.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
REGS1_k127_6699164_8	240015.ACP_0962	2.248e-124	436.0	COG0643@1|root,COG0643@2|Bacteria,3Y3WE@57723|Acidobacteria,2JMFQ@204432|Acidobacteriia	204432|Acidobacteriia	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
REGS1_k127_6699164_12	290397.Adeh_1371	2.599e-100	333.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42MR2@68525|delta/epsilon subdivisions,2WKKH@28221|Deltaproteobacteria,2Z00F@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg
REGS1_k127_6699164_19	290397.Adeh_1372	1.019e-54	201.0	COG1871@1|root,COG1871@2|Bacteria,1RAWA@1224|Proteobacteria,42QP1@68525|delta/epsilon subdivisions,2WQBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis	cheD1	-	3.5.1.44	ko:K03411	ko02030,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheD
REGS1_k127_6699164_21	240015.ACP_0965	1.56e-34	136.0	COG0745@1|root,COG0745@2|Bacteria,3Y53N@57723|Acidobacteria,2JN7U@204432|Acidobacteriia	204432|Acidobacteriia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
REGS1_k127_6699164_5	290397.Adeh_1373	2.857e-154	509.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB1	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
REGS1_k127_6699164_4	290397.Adeh_1374	1.157e-158	522.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
REGS1_k127_6699164_17	290397.Adeh_1375	5.33e-68	243.0	COG0835@1|root,COG0835@2|Bacteria,1PEGB@1224|Proteobacteria,43466@68525|delta/epsilon subdivisions,2X1U3@28221|Deltaproteobacteria,2YYW0@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
REGS1_k127_6699164_15	404589.Anae109_2430	3.077e-71	248.0	COG0460@1|root,COG2021@1|root,COG0460@2|Bacteria,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2WJRJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Homoserine_dh,NAD_binding_3
REGS1_k127_671541_0	290397.Adeh_0129	4.778e-147	495.0	COG1196@1|root,COG1196@2|Bacteria,1QX9C@1224|Proteobacteria,42VCQ@68525|delta/epsilon subdivisions,2WREF@28221|Deltaproteobacteria,2YW53@29|Myxococcales	28221|Deltaproteobacteria	D	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_671541_1	404589.Anae109_0131	1.144e-68	243.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,2YV3U@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
REGS1_k127_671541_4	1463879.JOHP01000003_gene5581	8.634e-11	68.0	COG0745@1|root,COG0745@2|Bacteria,2GMP1@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_671541_3	290397.Adeh_3077	1.012e-45	192.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
REGS1_k127_6732592_4	290397.Adeh_3985	2.213e-83	285.0	COG0584@1|root,COG0584@2|Bacteria,1MW6Z@1224|Proteobacteria	1224|Proteobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
REGS1_k127_6732592_6	419947.MRA_1849	1.486e-34	146.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
REGS1_k127_6732592_3	290397.Adeh_0903	4.81e-147	470.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2YTV2@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
REGS1_k127_6732592_1	404589.Anae109_0138	2.424e-185	582.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM galactose-1-phosphate uridylyltransferase	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
REGS1_k127_6732592_2	290397.Adeh_0133	5.549e-148	480.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WNXT@28221|Deltaproteobacteria,2YV4W@29|Myxococcales	28221|Deltaproteobacteria	EGP	of the major facilitator superfamily	agmP	-	-	ko:K08151	-	M00668	-	-	ko00000,ko00002,ko01504,ko02000	2.A.1.2.38,2.A.1.2.39,2.A.1.2.4,2.A.1.2.41,2.A.1.2.68,2.A.1.2.75	-	-	MFS_1,MFS_1_like,Sugar_tr
REGS1_k127_6732592_5	404589.Anae109_0136	4.624e-79	276.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MVME@1224|Proteobacteria,43AKG@68525|delta/epsilon subdivisions,2X60I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF
REGS1_k127_6732592_0	290397.Adeh_0131	0.0	1040.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2WIY0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
REGS1_k127_674556_7	404589.Anae109_2761	2.799e-62	214.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42PTC@68525|delta/epsilon subdivisions,2WM3S@28221|Deltaproteobacteria,2YTUU@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
REGS1_k127_674556_12	506534.Rhein_1340	6.79e-13	76.0	2CDAK@1|root,32SSG@2|Bacteria,1N6J4@1224|Proteobacteria,1SC0Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_674556_13	118168.MC7420_323	9.256e-10	63.0	2E3CI@1|root,32YBU@2|Bacteria,1GAH6@1117|Cyanobacteria,1HDX8@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_674556_14	644548.SCNU_07413	2.302e-05	54.0	COG2161@1|root,COG2161@2|Bacteria,2GUI1@201174|Actinobacteria,4GEEA@85026|Gordoniaceae	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	relF	GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_674556_11	1235457.C404_04250	2.562e-18	94.0	COG5460@1|root,COG5460@2|Bacteria,1PTUZ@1224|Proteobacteria,2VV0Z@28216|Betaproteobacteria,1K9N0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Uncharacterized conserved protein (DUF2164)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2164
REGS1_k127_674556_15	1282362.AEAC466_13980	0.0002382	50.0	2DS5G@1|root,33EM3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_674556_3	290397.Adeh_4128	3.398e-102	343.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
REGS1_k127_674556_9	404589.Anae109_2750	7.922e-42	169.0	COG0705@1|root,COG0705@2|Bacteria,1PRTP@1224|Proteobacteria,42M6N@68525|delta/epsilon subdivisions,2WJW4@28221|Deltaproteobacteria,2YVWN@29|Myxococcales	28221|Deltaproteobacteria	J	PFAM Rhomboid family protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
REGS1_k127_674556_6	404589.Anae109_1762	1.743e-64	229.0	COG0671@1|root,COG0671@2|Bacteria,1N034@1224|Proteobacteria	1224|Proteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_674556_0	404589.Anae109_2748	0.0	1667.0	COG0493@1|root,COG0543@1|root,COG1633@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,COG1633@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glutamate synthase (NADPH), homotetrameric	nfnA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
REGS1_k127_674556_2	290397.Adeh_2754	7.155e-112	365.0	COG2197@1|root,COG2197@2|Bacteria,1Q3AU@1224|Proteobacteria	1224|Proteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_674556_4	290397.Adeh_2753	2.227e-72	249.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,2YW6X@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
REGS1_k127_674556_10	290397.Adeh_2752	6.658e-27	111.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
REGS1_k127_674556_1	404589.Anae109_2740	2.488e-170	540.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2WIXX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
REGS1_k127_674556_8	404589.Anae109_2739	7.994e-55	196.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YUIT@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_6794672_1	404589.Anae109_4194	6.931e-124	416.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2YVA6@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_6794672_5	349521.HCH_05586	3.574e-48	181.0	COG1309@1|root,COG1309@2|Bacteria,1NBI7@1224|Proteobacteria	1224|Proteobacteria	K	BetI-type transcriptional repressor, C-terminal	-	-	-	ko:K02167	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_6,TetR_N
REGS1_k127_6794672_10	644284.Arch_1083	2.571e-29	132.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,4D65R@85005|Actinomycetales	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_6794672_9	504728.K649_03945	1.83e-29	130.0	COG4339@1|root,COG4339@2|Bacteria,1WMR8@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6794672_8	535289.Dtpsy_3051	1.338e-29	125.0	COG2323@1|root,COG2323@2|Bacteria,1RATW@1224|Proteobacteria,2VTFY@28216|Betaproteobacteria,4AJEE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
REGS1_k127_6794672_4	404589.Anae109_4070	2.018e-70	244.0	COG2032@1|root,COG2032@2|Bacteria,1RGV4@1224|Proteobacteria	1224|Proteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodC	GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0030288,GO:0030313,GO:0031975,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	iEcolC_1368.EcolC_1983	Sod_Cu
REGS1_k127_6794672_0	290397.Adeh_2622	3.107e-190	599.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,42MEN@68525|delta/epsilon subdivisions,2WIYF@28221|Deltaproteobacteria,2YUH6@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
REGS1_k127_6794672_3	404589.Anae109_1771	9.137e-111	391.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WUVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
REGS1_k127_6794672_2	290397.Adeh_0381	4.716e-123	398.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2YVHB@29|Myxococcales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
REGS1_k127_6794672_11	1265313.HRUBRA_00507	1.073e-18	91.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,1SEIJ@1236|Gammaproteobacteria,1J75Y@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
REGS1_k127_6794672_6	316067.Geob_0985	6.069e-37	144.0	COG3467@1|root,COG3467@2|Bacteria,1N4RH@1224|Proteobacteria,42TKQ@68525|delta/epsilon subdivisions,2WQ06@28221|Deltaproteobacteria,43VAD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
REGS1_k127_6794672_7	448385.sce4625	2.998e-33	134.0	COG4319@1|root,COG4319@2|Bacteria,1Q76Z@1224|Proteobacteria,434XK@68525|delta/epsilon subdivisions,2WZ8D@28221|Deltaproteobacteria,2Z1JT@29|Myxococcales	28221|Deltaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
REGS1_k127_680238_5	290397.Adeh_2246	3.569e-51	187.0	COG0526@1|root,COG0526@2|Bacteria,1MWDE@1224|Proteobacteria,42RCT@68525|delta/epsilon subdivisions,2WKJ9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
REGS1_k127_680238_1	1254432.SCE1572_33925	2.89e-191	610.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YTWP@29|Myxococcales	28221|Deltaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
REGS1_k127_680238_2	1121413.JMKT01000009_gene1954	8.934e-97	340.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
REGS1_k127_680238_4	717605.Theco_0031	2.131e-63	226.0	COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,4HAU2@91061|Bacilli,26RB5@186822|Paenibacillaceae	91061|Bacilli	IQ	reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
REGS1_k127_680238_3	1129794.C427_0619	9.039e-68	258.0	COG2267@1|root,COG2267@2|Bacteria,1RBQF@1224|Proteobacteria	1224|Proteobacteria	I	alpha/beta hydrolase fold	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Abhydrolase_1
REGS1_k127_680238_0	404589.Anae109_2599	0.0	1229.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
REGS1_k127_6814849_5	983917.RGE_21910	3.836e-124	406.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KIU5@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	ctpF	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
REGS1_k127_6814849_4	290397.Adeh_1374	1.182e-130	454.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
REGS1_k127_6814849_12	1173025.GEI7407_0198	9.884e-24	110.0	COG2319@1|root,COG2319@2|Bacteria,1GKHN@1117|Cyanobacteria,1HFV2@1150|Oscillatoriales	1117|Cyanobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6814849_7	404589.Anae109_3126	1.885e-101	347.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria,1QSA7@1224|Proteobacteria,42T4Y@68525|delta/epsilon subdivisions,2WPNT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thiol disulfide interchange protein dsbA	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4,VKOR
REGS1_k127_6814849_11	290397.Adeh_4024	3.291e-45	167.0	COG2154@1|root,COG2154@2|Bacteria,1PT4Z@1224|Proteobacteria,42VFE@68525|delta/epsilon subdivisions,2WSE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
REGS1_k127_6814849_8	290397.Adeh_4094	1.924e-67	230.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42TKK@68525|delta/epsilon subdivisions,2X5NX@28221|Deltaproteobacteria,2Z0PZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
REGS1_k127_6814849_2	404589.Anae109_0329	6.812e-190	613.0	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria,4340I@68525|delta/epsilon subdivisions,2X4FB@28221|Deltaproteobacteria,2Z047@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_6814849_1	404589.Anae109_0328	1.112e-205	652.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,2YUN7@29|Myxococcales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
REGS1_k127_6814849_15	1120983.KB894571_gene2396	9.641e-05	49.0	2EEKZ@1|root,319B9@2|Bacteria,1Q8P9@1224|Proteobacteria,2VCVV@28211|Alphaproteobacteria,1JQGX@119043|Rhodobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6814849_3	404589.Anae109_0323	5.024e-157	503.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_6814849_6	404589.Anae109_4141	1.718e-111	368.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
REGS1_k127_6814849_0	404589.Anae109_2402	1.037e-312	973.0	COG0343@1|root,COG4121@1|root,COG0343@2|Bacteria,COG4121@2|Bacteria,1MUCA@1224|Proteobacteria,42YYV@68525|delta/epsilon subdivisions,2WTRR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	-	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	Methyltransf_30,TGT
REGS1_k127_6814849_10	448385.sce4041	1.249e-45	192.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_6814849_9	754476.Q7A_3064	3.605e-66	240.0	COG0317@1|root,COG0460@1|root,COG0317@2|Bacteria,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,1RPEU@1236|Gammaproteobacteria,45ZV6@72273|Thiotrichales	72273|Thiotrichales	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
REGS1_k127_6818513_1	404589.Anae109_3551	9.088e-58	217.0	COG0727@1|root,COG0727@2|Bacteria,1NG7P@1224|Proteobacteria,42WC4@68525|delta/epsilon subdivisions,2WRUE@28221|Deltaproteobacteria,2Z2QH@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
REGS1_k127_6818513_2	671143.DAMO_2088	3.189e-54	198.0	COG2087@1|root,COG2087@2|Bacteria,2NRKT@2323|unclassified Bacteria	2|Bacteria	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568	2.7.1.156,2.7.7.62,6.3.5.10	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R05225,R06558	RC00002,RC00010,RC00428,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_2074,iECSE_1348.ECSE_2277,iECW_1372.ECW_m2165,iETEC_1333.ETEC_2103,iEcE24377_1341.EcE24377A_2275,iEcSMS35_1347.EcSMS35_1131,iEcolC_1368.EcolC_1635,iLF82_1304.LF82_0337,iSDY_1059.SDY_2240,iWFL_1372.ECW_m2165	CobU
REGS1_k127_6818513_0	671143.DAMO_2087	3.699e-110	377.0	COG2038@1|root,COG2038@2|Bacteria,2NQNG@2323|unclassified Bacteria	2|Bacteria	H	Phosphoribosyltransferase	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
REGS1_k127_6877675_6	290397.Adeh_3586	4.43e-75	259.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_6877675_1	404589.Anae109_3706	9.594e-102	338.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2WMWK@28221|Deltaproteobacteria,2YUTJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
REGS1_k127_6877675_3	404589.Anae109_3705	5.363e-89	301.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,42U86@68525|delta/epsilon subdivisions,2WX3A@28221|Deltaproteobacteria,2Z1AX@29|Myxococcales	28221|Deltaproteobacteria	M	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
REGS1_k127_6877675_4	404589.Anae109_2918	1.318e-86	317.0	COG0515@1|root,COG0515@2|Bacteria,1MVEU@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	pknB	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
REGS1_k127_6877675_8	1121123.AUAO01000001_gene1504	2.514e-06	57.0	2CX65@1|root,32T1A@2|Bacteria,1MZ48@1224|Proteobacteria,2VGPF@28211|Alphaproteobacteria,2KGUK@204458|Caulobacterales	204458|Caulobacterales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6877675_2	290397.Adeh_3990	6.74e-97	327.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
REGS1_k127_6877675_7	1144275.COCOR_03769	1.35e-52	201.0	COG2114@1|root,COG2114@2|Bacteria,1Q6BC@1224|Proteobacteria,432SK@68525|delta/epsilon subdivisions,2WXUK@28221|Deltaproteobacteria,2YZ4T@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
REGS1_k127_6877675_0	404589.Anae109_3704	1.062e-184	587.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,42NI1@68525|delta/epsilon subdivisions,2WK14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
REGS1_k127_6877675_5	404589.Anae109_3703	2.512e-80	273.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YTYT@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
REGS1_k127_694501_1	1267534.KB906759_gene1729	2.198e-101	350.0	COG1013@1|root,COG1013@2|Bacteria,3Y3NE@57723|Acidobacteria,2JIEM@204432|Acidobacteriia	2|Bacteria	C	Pyruvate ferredoxin oxidoreductase beta subunit C terminal	porB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
REGS1_k127_694501_0	1267534.KB906759_gene1728	1.65e-160	526.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,3Y3NX@57723|Acidobacteria,2JKIA@204432|Acidobacteriia	2|Bacteria	C	Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg	porA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iLJ478.TM1164	PFOR_II,POR,POR_N,Transketolase_C
REGS1_k127_6949869_4	1278073.MYSTI_03093	8.919e-08	66.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	coxB	-	1.9.3.1	ko:K02275,ko:K03640	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000,ko02000	2.C.1.2,3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrome_CBB3,OmpA
REGS1_k127_6949869_0	404589.Anae109_0339	4.498e-100	336.0	COG1149@1|root,COG1149@2|Bacteria,1QYGR@1224|Proteobacteria,43CD0@68525|delta/epsilon subdivisions,2X7NV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_6949869_1	1282360.ABAC460_21600	8.782e-22	113.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
REGS1_k127_6949869_3	404589.Anae109_0291	3.263e-12	81.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
REGS1_k127_6949869_2	290397.Adeh_4081	2.704e-18	88.0	COG0484@1|root,COG0484@2|Bacteria,1N40E@1224|Proteobacteria	1224|Proteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6969377_0	290397.Adeh_2746	8.388e-225	702.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2YXTZ@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_6969377_4	404589.Anae109_2736	1.285e-31	125.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2YVWU@29|Myxococcales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_6969377_2	404589.Anae109_2737	4.856e-113	386.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YUT4@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_6969377_1	290397.Adeh_2749	2.209e-150	490.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,2YU16@29|Myxococcales	28221|Deltaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
REGS1_k127_6969377_3	404589.Anae109_2739	7.501e-92	303.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YUIT@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_7036123_0	861299.J421_2748	0.0	1321.0	COG0178@1|root,COG0178@2|Bacteria,1ZTDJ@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
REGS1_k127_7053784_2	404589.Anae109_0696	1.088e-12	70.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
REGS1_k127_7053784_0	502025.Hoch_6466	1.814e-102	344.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42UAF@68525|delta/epsilon subdivisions,2WQGM@28221|Deltaproteobacteria,2YVSD@29|Myxococcales	28221|Deltaproteobacteria	O	ADP-ribosylglycohydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH,Inositol_P
REGS1_k127_7053784_1	290397.Adeh_4210	1.053e-29	126.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	B_lectin,PQQ_2,PQQ_3,VanY
REGS1_k127_7056250_3	391625.PPSIR1_16550	2.619e-16	94.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
REGS1_k127_7056250_0	1125863.JAFN01000001_gene308	4.41e-291	924.0	COG0046@1|root,COG0046@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
REGS1_k127_7056250_2	404589.Anae109_3017	7.861e-42	171.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M1R@68525|delta/epsilon subdivisions,2WK3J@28221|Deltaproteobacteria,2YZH3@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,Response_reg
REGS1_k127_7056250_4	395493.BegalDRAFT_2399	1.077e-13	85.0	COG4637@1|root,COG4938@1|root,COG4637@2|Bacteria,COG4938@2|Bacteria,1NEEG@1224|Proteobacteria,1RZMD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,DUF3696
REGS1_k127_7056250_1	290397.Adeh_3427	4.122e-185	587.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,2YZJS@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
REGS1_k127_7069536_2	404589.Anae109_2092	3.06e-272	853.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
REGS1_k127_7069536_7	404589.Anae109_2093	2.061e-120	420.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_2093|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7069536_4	404589.Anae109_2094	2.801e-214	683.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUMV@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_7069536_0	404589.Anae109_2098	0.0	1434.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_7069536_6	290397.Adeh_1705	5.094e-132	426.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	CP_0969	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
REGS1_k127_7069536_8	404589.Anae109_2104	2.106e-113	387.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
REGS1_k127_7069536_3	404589.Anae109_2106	5.177e-246	770.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	pfam abc1	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH,WaaY
REGS1_k127_7069536_1	290397.Adeh_1698	0.0	1314.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,2YTZJ@29|Myxococcales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
REGS1_k127_7069536_11	290397.Adeh_1697	3.241e-30	122.0	2DYE1@1|root,349AP@2|Bacteria,1NZTB@1224|Proteobacteria	1224|Proteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
REGS1_k127_7069536_12	290397.Adeh_1696	5.111e-27	113.0	2DYE1@1|root,349AP@2|Bacteria,1NZTB@1224|Proteobacteria	1224|Proteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
REGS1_k127_7099112_13	290397.Adeh_1809	5.491e-23	105.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K13695	-	-	-	-	ko00000,ko01002	-	-	-	CHAP,NLPC_P60
REGS1_k127_7099112_0	290397.Adeh_1808	0.0	1196.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YWBK@29|Myxococcales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_7099112_1	290397.Adeh_1807	5.588e-292	906.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
REGS1_k127_7099112_9	290397.Adeh_1780	6.672e-69	242.0	COG0546@1|root,COG0546@2|Bacteria,1RBMZ@1224|Proteobacteria,42RG3@68525|delta/epsilon subdivisions,2WZ2N@28221|Deltaproteobacteria,2Z16Z@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_7099112_7	290397.Adeh_1779	3.551e-123	413.0	COG0077@1|root,COG0077@2|Bacteria,1MU60@1224|Proteobacteria,42MGN@68525|delta/epsilon subdivisions,2WJET@28221|Deltaproteobacteria,2YV42@29|Myxococcales	28221|Deltaproteobacteria	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
REGS1_k127_7099112_5	290397.Adeh_1777	4.657e-160	515.0	COG1752@1|root,COG1752@2|Bacteria,1PEH4@1224|Proteobacteria,42XKH@68525|delta/epsilon subdivisions,2WTA6@28221|Deltaproteobacteria,2YWD2@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
REGS1_k127_7099112_3	404589.Anae109_2041	2.334e-223	699.0	COG1236@1|root,COG1236@2|Bacteria,1MUDD@1224|Proteobacteria,42N91@68525|delta/epsilon subdivisions,2WIMM@28221|Deltaproteobacteria,2YUD9@29|Myxococcales	28221|Deltaproteobacteria	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
REGS1_k127_7099112_10	290397.Adeh_1775	9.172e-55	198.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,42T10@68525|delta/epsilon subdivisions,2WPNN@28221|Deltaproteobacteria,2YVNK@29|Myxococcales	28221|Deltaproteobacteria	L	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4
REGS1_k127_7099112_4	290397.Adeh_1771	9.134e-189	603.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_7099112_8	290397.Adeh_1768	1.907e-122	396.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42QN5@68525|delta/epsilon subdivisions,2WMD7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_7099112_6	290397.Adeh_1767	2.11e-140	466.0	2EM41@1|root,33ETI@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
REGS1_k127_7099112_2	290397.Adeh_1766	3.018e-264	820.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YX7D@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA1	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
REGS1_k127_7099112_18	89187.ISM_11845	8.276e-07	62.0	COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,2U9R9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Peptidoglycan-binding protein LysM	-	-	-	-	-	-	-	-	-	-	-	-	BON,LysM
REGS1_k127_7099112_15	1123487.KB892835_gene3478	1.117e-10	74.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,2VRAI@28216|Betaproteobacteria,2KW74@206389|Rhodocyclales	206389|Rhodocyclales	NT	Chemotaxis signal transduction protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_7099112_14	861299.J421_0186	9.192e-12	78.0	COG1536@1|root,COG1536@2|Bacteria,1ZTEY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	N	FliG N-terminal domain	-	-	-	ko:K02410	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035	-	-	-	FliG_C,FliG_M,FliG_N
REGS1_k127_7099112_17	1304284.L21TH_2242	7.199e-10	64.0	COG1291@1|root,COG1291@2|Bacteria,1TRH1@1239|Firmicutes,24AEJ@186801|Clostridia,36E57@31979|Clostridiaceae	186801|Clostridia	N	PFAM MotA TolQ ExbB proton channel	motA	-	-	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	MotA_ExbB
REGS1_k127_7128855_1	1242864.D187_001318	7.628e-39	164.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YUB2@29|Myxococcales	28221|Deltaproteobacteria	KL	Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
REGS1_k127_7128855_5	1144275.COCOR_07857	4.406e-29	120.0	COG3636@1|root,COG3636@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
REGS1_k127_7128855_0	163908.KB235896_gene2699	1.207e-47	175.0	COG5340@1|root,COG5340@2|Bacteria,1G68S@1117|Cyanobacteria,1HPK0@1161|Nostocales	1117|Cyanobacteria	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
REGS1_k127_7128855_9	903818.KI912268_gene2536	2.237e-11	69.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,3Y66N@57723|Acidobacteria	57723|Acidobacteria	L	Type III restriction enzyme res subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7128855_8	114615.BRADO5844	3.342e-17	88.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1QVE4@1224|Proteobacteria,2TUH9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	DNA primase small subunit	-	-	-	-	-	-	-	-	-	-	-	-	ResIII
REGS1_k127_7128855_3	1173028.ANKO01000044_gene805	3.85e-30	121.0	COG1669@1|root,COG1669@2|Bacteria,1G804@1117|Cyanobacteria,1HCHE@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
REGS1_k127_7128855_4	489825.LYNGBM3L_05410	2.123e-29	121.0	COG2361@1|root,COG2361@2|Bacteria,1G7XA@1117|Cyanobacteria,1HCYZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
REGS1_k127_7128855_6	1144275.COCOR_07857	6.043e-29	119.0	COG3636@1|root,COG3636@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
REGS1_k127_7128855_7	33876.JNXY01000003_gene67	1.389e-24	104.0	2EATS@1|root,334VI@2|Bacteria,2GUEE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7154758_1	290397.Adeh_2484	2.298e-121	399.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
REGS1_k127_7154758_2	404589.Anae109_1381	9.796e-107	357.0	COG0613@1|root,COG0613@2|Bacteria,1RF04@1224|Proteobacteria,42RR4@68525|delta/epsilon subdivisions,2WNC8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP,PHP_C
REGS1_k127_7154758_4	290397.Adeh_2488	4.688e-23	100.0	2AMRI@1|root,32B6T@2|Bacteria,1Q1RN@1224|Proteobacteria,43EYM@68525|delta/epsilon subdivisions,2X2M7@28221|Deltaproteobacteria,2Z1YI@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7154758_0	404589.Anae109_1378	1.4e-196	623.0	COG0585@1|root,COG0585@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
REGS1_k127_7154758_5	1278073.MYSTI_06642	3.37e-16	83.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42M2V@68525|delta/epsilon subdivisions,2WKEB@28221|Deltaproteobacteria,2YYQ6@29|Myxococcales	28221|Deltaproteobacteria	L	Putative RNA methylase family UPF0020	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
REGS1_k127_7160112_12	497964.CfE428DRAFT_1238	6.308e-88	299.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_7160112_16	497964.CfE428DRAFT_1239	2.895e-46	189.0	2BZ6D@1|root,2ZC6J@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7160112_10	497964.CfE428DRAFT_1241	2.914e-102	355.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	GH3
REGS1_k127_7160112_7	404589.Anae109_2886	4.808e-151	485.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YZRV@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
REGS1_k127_7160112_21	667014.Thein_1542	0.0005558	54.0	COG1033@1|root,COG1033@2|Bacteria,2GIBA@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Patched family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
REGS1_k127_7160112_6	1005999.GLGR_3548	9.335e-157	506.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,1S087@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_7160112_9	1005999.GLGR_3547	4.864e-122	407.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,1S1D8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_7160112_11	330214.NIDE2810	4.597e-88	293.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_7160112_3	290397.Adeh_0107	1.649e-205	653.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	bamV	-	2.7.13.3	ko:K07710,ko:K10125	ko02020,map02020	M00500,M00504	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
REGS1_k127_7160112_2	404589.Anae109_0110	1.907e-230	752.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_7160112_15	404589.Anae109_4479	6.12e-48	183.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2YVS3@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_7160112_8	404589.Anae109_0107	9.259e-137	456.0	COG2887@1|root,COG2887@2|Bacteria	2|Bacteria	L	Belongs to the helicase family. UvrD subfamily	uvrD3	-	-	-	-	-	-	-	-	-	-	-	AAA_19,PDDEXK_1,UvrD-helicase,UvrD_C
REGS1_k127_7160112_17	290397.Adeh_0101	5.144e-36	157.0	COG0745@1|root,COG0745@2|Bacteria	290397.Adeh_0101|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7160112_1	404589.Anae109_0101	2.305e-231	722.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,2YU1M@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
REGS1_k127_7160112_19	404589.Anae109_0079	5.707e-31	136.0	COG5608@1|root,COG5608@2|Bacteria,1N4VR@1224|Proteobacteria	1224|Proteobacteria	S	Late embryogenesis abundant protein	-	-	-	-	-	-	-	-	-	-	-	-	LEA_2
REGS1_k127_7160112_20	1166018.FAES_1717	1.688e-18	95.0	2EMS7@1|root,33FEN@2|Bacteria,4NYP9@976|Bacteroidetes,47T2X@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	ko:K11934	-	-	-	-	ko00000,ko02000	1.B.6.2.1	-	-	OMP_b-brl
REGS1_k127_7160112_18	349521.HCH_06729	4.979e-35	154.0	COG5083@1|root,COG5083@2|Bacteria,1R6Q7@1224|Proteobacteria,1S13P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein involved in plasmid maintenance	-	-	-	-	-	-	-	-	-	-	-	-	LNS2
REGS1_k127_7160112_13	290397.Adeh_0099	2.648e-60	212.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
REGS1_k127_7160112_4	290397.Adeh_0098	4.594e-189	597.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales	28221|Deltaproteobacteria	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
REGS1_k127_7160112_14	290397.Adeh_3004	4.26e-52	194.0	COG2905@1|root,COG2905@2|Bacteria,1QTTR@1224|Proteobacteria,42TN6@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	hrp1	-	-	-	-	-	-	-	-	-	-	-	CBS
REGS1_k127_7160112_5	452637.Oter_3478	9.731e-179	567.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
REGS1_k127_7160112_0	290397.Adeh_0097	1.4e-289	899.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YU2G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_7169278_0	234267.Acid_7036	5.096e-56	214.0	COG0389@1|root,COG0389@2|Bacteria,3Y3EV@57723|Acidobacteria	57723|Acidobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
REGS1_k127_7177038_0	489825.LYNGBM3L_41540	2.869e-45	169.0	COG0395@1|root,COG0395@2|Bacteria,1G1XU@1117|Cyanobacteria,1H8HR@1150|Oscillatoriales	1117|Cyanobacteria	G	PFAM Inward rectifier potassium channel	-	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
REGS1_k127_7177038_2	234267.Acid_4888	3.3e-14	84.0	2CAA3@1|root,2ZJET@2|Bacteria,3Y492@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7177038_1	1267535.KB906767_gene3817	4.495e-44	164.0	COG5611@1|root,COG5611@2|Bacteria	2|Bacteria	S	PIN domain	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_7182428_9	404589.Anae109_3645	8.577e-32	125.0	COG0526@1|root,COG0526@2|Bacteria,1N0R9@1224|Proteobacteria,42UD9@68525|delta/epsilon subdivisions,2WQ0H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM Thioredoxin	trx-2	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_7182428_7	404589.Anae109_3646	6.227e-87	293.0	COG4232@1|root,COG4232@2|Bacteria,1PK9S@1224|Proteobacteria,42PV0@68525|delta/epsilon subdivisions,2WJPK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	PFAM cytochrome c biogenesis protein, transmembrane region	dsbD	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD
REGS1_k127_7182428_1	404589.Anae109_3647	2.619e-171	544.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,42MF8@68525|delta/epsilon subdivisions,2WJFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
REGS1_k127_7182428_10	290397.Adeh_1028	1.313e-22	114.0	COG0526@1|root,COG0526@2|Bacteria,1N728@1224|Proteobacteria,42V0C@68525|delta/epsilon subdivisions,2WRJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CO	redox-active disulfide protein 2	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
REGS1_k127_7182428_6	1192034.CAP_6745	1.908e-109	378.0	COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	-	-	3.5.4.25	ko:K01497	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125	R00425	RC00293,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2
REGS1_k127_7182428_5	290397.Adeh_0507	4.237e-123	403.0	COG3380@1|root,COG3380@2|Bacteria,1R5C0@1224|Proteobacteria,435D1@68525|delta/epsilon subdivisions,2X984@28221|Deltaproteobacteria,2Z2IU@29|Myxococcales	28221|Deltaproteobacteria	S	Flavin containing amine oxidoreductase	-	-	-	ko:K06955	-	-	-	-	ko00000	-	-	-	Amino_oxidase,NAD_binding_8
REGS1_k127_7182428_8	404589.Anae109_0472	1.549e-64	223.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2WP2P@28221|Deltaproteobacteria,2YVDR@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
REGS1_k127_7182428_3	290397.Adeh_3951	1.102e-159	508.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2YUI6@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
REGS1_k127_7182428_4	404589.Anae109_0475	5.071e-128	421.0	COG1651@1|root,COG1651@2|Bacteria,1MX2T@1224|Proteobacteria,42S4E@68525|delta/epsilon subdivisions,2WNJ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	SurA_N_3,Thioredoxin_4
REGS1_k127_7182428_0	404589.Anae109_0476	6.341e-189	599.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
REGS1_k127_7182428_11	666681.M301_0979	3.247e-16	80.0	2DNSI@1|root,32YXC@2|Bacteria,1N7K2@1224|Proteobacteria,2VVXF@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7182428_2	316067.Geob_0014	1.303e-168	535.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,43TYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
REGS1_k127_7187385_3	290397.Adeh_3787	2.045e-82	293.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42SHB@68525|delta/epsilon subdivisions,2WUKC@28221|Deltaproteobacteria,2YV2F@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_7187385_0	290397.Adeh_3788	6.372e-176	573.0	COG0577@1|root,COG0577@2|Bacteria,1QXV8@1224|Proteobacteria,43C7Z@68525|delta/epsilon subdivisions,2X7IB@28221|Deltaproteobacteria,2YUZK@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
REGS1_k127_7187385_5	357808.RoseRS_2451	3.366e-44	179.0	COG4870@1|root,COG4932@1|root,COG5513@1|root,COG4870@2|Bacteria,COG4932@2|Bacteria,COG5513@2|Bacteria,2GA24@200795|Chloroflexi,377PH@32061|Chloroflexia	2|Bacteria	MO	Carboxypeptidase regulatory-like domain	-	-	3.4.22.15	ko:K01365,ko:K02030,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418	M00236	-	-	ko00000,ko00001,ko00002,ko00537,ko01000,ko01002,ko02000,ko03110	3.A.1.3	-	-	CarboxypepD_reg,Inhibitor_I42,Peptidase_C1
REGS1_k127_7187385_2	290397.Adeh_3792	4.939e-111	364.0	COG0428@1|root,COG0428@2|Bacteria,1RF7H@1224|Proteobacteria,42Y2I@68525|delta/epsilon subdivisions,2WSUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
REGS1_k127_7187385_4	404589.Anae109_3909	3.493e-71	244.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
REGS1_k127_7203704_4	459349.CLOAM1631	4.882e-48	179.0	COG0167@1|root,COG0493@1|root,COG1148@1|root,COG0167@2|Bacteria,COG0493@2|Bacteria,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	pds	-	1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9	ko:K00207,ko:K00219,ko:K00317,ko:K02293,ko:K10797,ko:K12527,ko:K17723	ko00240,ko00360,ko00410,ko00450,ko00680,ko00770,ko00906,ko00983,ko01100,ko01110,ko01120,ko01200,map00240,map00360,map00410,map00450,map00680,map00770,map00906,map00983,map01100,map01110,map01120,map01200	M00046,M00097	R00977,R00978,R01414,R01415,R01588,R02252,R02511,R04786,R04787,R07229,R07510,R08226,R09652,R09653,R09654,R11026	RC00072,RC00123,RC00185,RC00556,RC00557,RC00669,RC00732,RC01214,RC01958,RC02245,RC02420,RC03092,RC03093	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase,Fer4,Fer4_4,Pyr_redox_2
REGS1_k127_7203704_3	290397.Adeh_1018	2.024e-77	275.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
REGS1_k127_7203704_2	290397.Adeh_1019	6.728e-148	498.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42SYF@68525|delta/epsilon subdivisions,2WPNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
REGS1_k127_7203704_0	290397.Adeh_1020	0.0	1470.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
REGS1_k127_7203704_1	1121920.AUAU01000024_gene2387	1.7e-223	704.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	bchE	GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Fer4_12,Radical_SAM
REGS1_k127_7214650_6	290397.Adeh_2176	2.006e-05	56.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria,2Z0ES@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
REGS1_k127_7214650_1	290397.Adeh_2070	1.313e-190	599.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_7214650_0	290397.Adeh_2071	2.333e-275	855.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
REGS1_k127_7214650_3	1297742.A176_01978	5.049e-47	181.0	COG0596@1|root,COG0596@2|Bacteria,1R4N4@1224|Proteobacteria,434SV@68525|delta/epsilon subdivisions,2WZ3Y@28221|Deltaproteobacteria,2Z19T@29|Myxococcales	28221|Deltaproteobacteria	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
REGS1_k127_7214650_4	404589.Anae109_4117	1.547e-34	141.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WQ3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	cold-shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_7214650_2	404589.Anae109_3649	1.138e-89	336.0	2CJTZ@1|root,32SAS@2|Bacteria,1N3WB@1224|Proteobacteria,42XK5@68525|delta/epsilon subdivisions,2WSKQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3553
REGS1_k127_7228514_2	929562.Emtol_2656	4.926e-07	57.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	VP1093	-	-	ko:K06075,ko:K18909	-	M00705	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MarR,MarR_2
REGS1_k127_7228514_0	290397.Adeh_2186	2.97e-53	193.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5EQ@28221|Deltaproteobacteria,2Z35B@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_7228514_1	290397.Adeh_3897	1.977e-50	184.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
REGS1_k127_7230123_1	404589.Anae109_4269	2.042e-85	284.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2YWT1@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
REGS1_k127_7230123_2	338969.Rfer_0862	5.547e-73	249.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2VQ0V@28216|Betaproteobacteria,4AGUW@80864|Comamonadaceae	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
REGS1_k127_7230123_0	246197.MXAN_2028	1.435e-102	346.0	COG3148@1|root,COG3148@2|Bacteria,1MZCN@1224|Proteobacteria,42S7K@68525|delta/epsilon subdivisions,2WQI0@28221|Deltaproteobacteria,2YW7K@29|Myxococcales	28221|Deltaproteobacteria	S	DTW	-	-	-	ko:K05812	-	-	-	-	ko00000	-	-	-	DTW
REGS1_k127_7230123_3	1121920.AUAU01000023_gene2441	0.0003521	51.0	COG0457@1|root,COG0457@2|Bacteria	1121920.AUAU01000023_gene2441|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7261709_6	290397.Adeh_4051	1.001e-30	121.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,42SBM@68525|delta/epsilon subdivisions,2WQ24@28221|Deltaproteobacteria,2Z0M5@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
REGS1_k127_7261709_0	290397.Adeh_4052	3.434e-254	790.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42MXN@68525|delta/epsilon subdivisions,2WJN0@28221|Deltaproteobacteria,2YWK3@29|Myxococcales	28221|Deltaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657,ko:K13503	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
REGS1_k127_7261709_3	404589.Anae109_0375	4.95e-89	319.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QTS@68525|delta/epsilon subdivisions,2WN02@28221|Deltaproteobacteria,2YXCZ@29|Myxococcales	28221|Deltaproteobacteria	EH	Peptidase C26	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2496	GATase
REGS1_k127_7261709_1	404589.Anae109_0374	3.204e-154	507.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria,2YUVG@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	GATase,Glycos_trans_3N,Glycos_transf_3
REGS1_k127_7261709_2	404589.Anae109_0373	3.512e-108	372.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2YV8U@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
REGS1_k127_7261709_4	290397.Adeh_4056	1.865e-75	259.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,2YXEI@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
REGS1_k127_7261709_5	290397.Adeh_4057	1.341e-71	254.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,2YU86@29|Myxococcales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_7284741_0	290397.Adeh_0154	2.17e-205	644.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
REGS1_k127_7290652_1	1125863.JAFN01000001_gene3405	1.836e-95	325.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
REGS1_k127_7290652_0	1121430.JMLG01000037_gene147	3.556e-180	580.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,260CD@186807|Peptococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
REGS1_k127_7290652_2	330214.NIDE2054	1.589e-75	257.0	COG1186@1|root,COG1186@2|Bacteria,3J0EX@40117|Nitrospirae	40117|Nitrospirae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_7294285_9	290397.Adeh_4191	1.35e-21	95.0	COG0457@1|root,COG0457@2|Bacteria,1QQ0R@1224|Proteobacteria,433U8@68525|delta/epsilon subdivisions,2X3GZ@28221|Deltaproteobacteria,2YW20@29|Myxococcales	28221|Deltaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,zinc_ribbon_4
REGS1_k127_7294285_5	290397.Adeh_4190	7.818e-48	175.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria,2Z0RF@29|Myxococcales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
REGS1_k127_7294285_7	404589.Anae109_4339	7.154e-34	132.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,2YW6Q@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
REGS1_k127_7294285_1	404589.Anae109_4338	1.552e-244	778.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YTXJ@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
REGS1_k127_7294285_0	404589.Anae109_4336	1.848e-249	784.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2YUCW@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
REGS1_k127_7294285_2	290397.Adeh_4186	3.535e-162	520.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,2YUP1@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
REGS1_k127_7294285_3	290397.Adeh_4185	1.272e-90	323.0	COG0395@1|root,COG0395@2|Bacteria,1REG1@1224|Proteobacteria,43CD2@68525|delta/epsilon subdivisions,2X7NX@28221|Deltaproteobacteria,2Z3H9@29|Myxococcales	28221|Deltaproteobacteria	C	Inward rectifier potassium channel	-	-	-	ko:K08715	-	-	-	-	ko00000,ko02000	1.A.2.2	-	-	IRK
REGS1_k127_7294285_4	404589.Anae109_4328	2.06e-54	194.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
REGS1_k127_7294285_6	404589.Anae109_4327	1.824e-40	150.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria	1224|Proteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
REGS1_k127_7294285_10	1242864.D187_010206	4.188e-19	89.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,2YUC0@29|Myxococcales	28221|Deltaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
REGS1_k127_7340793_3	290397.Adeh_1562	9.454e-95	325.0	COG4987@1|root,COG4987@2|Bacteria	2|Bacteria	V	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC	cydC	-	-	ko:K06148,ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1,3.A.1.129	-	-	ABC_membrane,ABC_tran
REGS1_k127_7340793_4	290397.Adeh_1564	7.433e-53	194.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,2YVE5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
REGS1_k127_7340793_0	404589.Anae109_2250	1.803e-320	1005.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
REGS1_k127_7340793_2	404589.Anae109_2248	2.11e-102	341.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1N3ZM@1224|Proteobacteria,42TUU@68525|delta/epsilon subdivisions,2WQ8Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KP	PFAM iron dependent repressor	ideR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
REGS1_k127_7340793_8	290397.Adeh_1575	3.776e-23	103.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K12065,ko:K13052	-	-	-	-	ko00000,ko02044,ko03036	3.A.7.11.1	-	-	DivIC
REGS1_k127_7340793_1	290397.Adeh_1576	4.834e-256	815.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WPGK@28221|Deltaproteobacteria,2YTYN@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GGDEF
REGS1_k127_7340793_6	404589.Anae109_2239	6.976e-35	134.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,2YY78@29|Myxococcales	28221|Deltaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
REGS1_k127_7367779_0	404589.Anae109_2810	1.509e-97	321.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria	1224|Proteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
REGS1_k127_7367779_2	1254432.SCE1572_04465	1.278e-17	96.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42SDE@68525|delta/epsilon subdivisions,2WPS3@28221|Deltaproteobacteria,2Z2XC@29|Myxococcales	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
REGS1_k127_7367779_1	404589.Anae109_3687	1.249e-44	163.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_7374841_1	1121918.ARWE01000001_gene2188	3.614e-95	319.0	2DBEC@1|root,2Z8RY@2|Bacteria,1MXRI@1224|Proteobacteria,42ZNW@68525|delta/epsilon subdivisions,2WUUT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF3943)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3943
REGS1_k127_7374841_3	324057.Pjdr2_1478	8.114e-68	256.0	COG0515@1|root,COG0515@2|Bacteria	324057.Pjdr2_1478|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7374841_4	497964.CfE428DRAFT_0449	1.513e-35	149.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2,SpoIIE
REGS1_k127_7374841_0	497964.CfE428DRAFT_0448	7.619e-98	327.0	COG2304@1|root,COG2304@2|Bacteria,46VUT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7374841_2	1499967.BAYZ01000026_gene1558	5.037e-91	301.0	COG0376@1|root,COG0376@2|Bacteria,2NQNQ@2323|unclassified Bacteria	2|Bacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
REGS1_k127_7390279_1	443143.GM18_2183	6.429e-151	511.0	COG0579@1|root,COG0579@2|Bacteria,1N0QB@1224|Proteobacteria,42N0R@68525|delta/epsilon subdivisions,2WMPF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Fer2_BFD
REGS1_k127_7390279_0	290397.Adeh_1896	5.709e-284	877.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,2YTWQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
REGS1_k127_7430421_4	404589.Anae109_3909	4.988e-88	327.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,2YVBI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
REGS1_k127_7430421_0	290397.Adeh_3789	1.036e-161	529.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,2YURT@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
REGS1_k127_7430421_8	404589.Anae109_2412	3.935e-55	198.0	2ESNI@1|root,33K73@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
REGS1_k127_7430421_1	215803.DB30_2319	1.355e-147	473.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_7430421_2	1278073.MYSTI_06257	2.304e-100	337.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2YURN@29|Myxococcales	28221|Deltaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_7430421_9	1144275.COCOR_06153	1.907e-35	149.0	2DQMB@1|root,337KD@2|Bacteria,1NKJH@1224|Proteobacteria,42X0X@68525|delta/epsilon subdivisions,2WSJT@28221|Deltaproteobacteria,2YVNT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7430421_3	1278073.MYSTI_06255	1.191e-92	336.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2WKKE@28221|Deltaproteobacteria,2YXC9@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
REGS1_k127_7430421_5	1278073.MYSTI_06254	5.546e-78	284.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2YV46@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
REGS1_k127_7430421_13	460265.Mnod_1009	0.0001725	52.0	COG0457@1|root,COG0457@2|Bacteria,1RFKU@1224|Proteobacteria,2U719@28211|Alphaproteobacteria,1JZA5@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	-
REGS1_k127_7430421_6	483219.LILAB_35770	2.222e-72	267.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2WM9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
REGS1_k127_7430421_11	398720.MED217_00280	1.335e-14	88.0	COG0457@1|root,COG0457@2|Bacteria,4NF5V@976|Bacteroidetes,1HYKU@117743|Flavobacteriia,2XHWA@283735|Leeuwenhoekiella	976|Bacteroidetes	S	Bacterial SH3 domain	batE	-	-	-	-	-	-	-	-	-	-	-	SH3_3,SH3_4,TPR_1,TPR_11,TPR_16,TPR_2
REGS1_k127_7430421_12	1269813.ATUL01000001_gene1189	9.172e-14	84.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
REGS1_k127_7430421_7	290397.Adeh_3990	1.328e-60	216.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
REGS1_k127_7458688_2	290397.Adeh_0845	8.95e-129	436.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
REGS1_k127_7458688_3	290397.Adeh_0844	1.312e-115	381.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,42PD0@68525|delta/epsilon subdivisions,2WJV3@28221|Deltaproteobacteria,2YWBY@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
REGS1_k127_7458688_0	290397.Adeh_0843	1.162e-279	863.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions,2WM3R@28221|Deltaproteobacteria,2YX6W@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
REGS1_k127_7458688_4	290397.Adeh_0841	6.986e-63	226.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2WMW2@28221|Deltaproteobacteria,2YVEE@29|Myxococcales	28221|Deltaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
REGS1_k127_7458688_1	290397.Adeh_0326	2.207e-201	659.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
REGS1_k127_7458688_6	177437.HRM2_42600	1.256e-22	113.0	COG1917@1|root,COG1917@2|Bacteria,1N2JS@1224|Proteobacteria,42TR3@68525|delta/epsilon subdivisions,2WQ4M@28221|Deltaproteobacteria,2MKQJ@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_7514375_7	1220534.B655_1269	1.035e-36	143.0	COG5015@1|root,arCOG00528@2157|Archaea,2XY7F@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
REGS1_k127_7514375_5	316067.Geob_1163	3.084e-54	202.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K18325	-	M00647	-	-	ko00000,ko00002,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC,Response_reg
REGS1_k127_7514375_0	404589.Anae109_0368	2.549e-179	594.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2YXNS@29|Myxococcales	28221|Deltaproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,DAHP_synth_1,PDT
REGS1_k127_7514375_1	404589.Anae109_0367	3.504e-168	534.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,2YXNS@29|Myxococcales	28221|Deltaproteobacteria	E	phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,DAHP_synth_1,PDT
REGS1_k127_7514375_3	316067.Geob_3342	2.175e-126	423.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42MCH@68525|delta/epsilon subdivisions,2WJPZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_7514375_8	246197.MXAN_3194	4.357e-29	121.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393,LMF1
REGS1_k127_7514375_9	1340493.JNIF01000003_gene2551	6.426e-22	97.0	COG3369@1|root,COG3369@2|Bacteria,3Y5KG@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Iron sulphur-containing domain, CDGSH-type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
REGS1_k127_7514375_4	404589.Anae109_0364	2.725e-109	358.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2YTW3@29|Myxococcales	28221|Deltaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
REGS1_k127_7514375_2	290397.Adeh_4064	8.905e-149	486.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,2YV2A@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
REGS1_k127_7609236_3	404589.Anae109_3149	2.067e-08	66.0	COG3047@1|root,COG3047@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07275	-	-	-	-	ko00000	-	-	-	OMP_b-brl
REGS1_k127_7609236_0	404589.Anae109_3899	6.203e-156	497.0	COG2382@1|root,COG2382@2|Bacteria,1QX0K@1224|Proteobacteria	1224|Proteobacteria	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
REGS1_k127_7609236_1	404589.Anae109_3617	3.261e-120	421.0	COG0006@1|root,COG0006@2|Bacteria,1N763@1224|Proteobacteria,42PVQ@68525|delta/epsilon subdivisions,2WK4N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM peptidase M24	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
REGS1_k127_7632721_6	1280692.AUJL01000019_gene936	2.218e-06	51.0	2BE7V@1|root,327YV@2|Bacteria,1UTVX@1239|Firmicutes,254K5@186801|Clostridia,36TRY@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7632721_5	404589.Anae109_0016	6.157e-60	216.0	COG3266@1|root,COG3266@2|Bacteria,1N9VA@1224|Proteobacteria,42VXQ@68525|delta/epsilon subdivisions,2WSBF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7632721_2	404589.Anae109_0015	3.205e-123	404.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2YVDG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
REGS1_k127_7632721_3	290397.Adeh_0013	5.561e-70	248.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,42UAT@68525|delta/epsilon subdivisions,2WQ31@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
REGS1_k127_7632721_0	404589.Anae109_0013	0.0	1617.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
REGS1_k127_7632721_1	404589.Anae109_0012	6.905e-150	481.0	COG0189@1|root,COG0189@2|Bacteria,1MX62@1224|Proteobacteria,42NIA@68525|delta/epsilon subdivisions,2WM87@28221|Deltaproteobacteria,2YUDN@29|Myxococcales	28221|Deltaproteobacteria	HJ	Belongs to the RimK family	rimK	-	6.3.2.32	ko:K05844,ko:K14940	ko00680,ko01120,map00680,map01120	-	R09401	RC00064,RC00090	ko00000,ko00001,ko01000,ko03009	-	-	-	RimK
REGS1_k127_7683528_1	404589.Anae109_3459	1.255e-142	463.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2Z110@29|Myxococcales	28221|Deltaproteobacteria	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
REGS1_k127_7683528_0	404589.Anae109_3458	8.546e-260	807.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2YU74@29|Myxococcales	28221|Deltaproteobacteria	M	Mur ligase family, catalytic domain	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_7683528_2	290397.Adeh_4019	2.496e-66	228.0	COG2050@1|root,COG2050@2|Bacteria,1RKGI@1224|Proteobacteria,42WI1@68525|delta/epsilon subdivisions,2WSAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Domain of unknown function (DUF4442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4442
REGS1_k127_7710720_19	215803.DB30_5303	6.736e-17	80.0	COG3215@1|root,COG3215@2|Bacteria,1Q2S4@1224|Proteobacteria,43266@68525|delta/epsilon subdivisions,2WXR8@28221|Deltaproteobacteria,2YVFJ@29|Myxococcales	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
REGS1_k127_7710720_13	404589.Anae109_3395	3.136e-47	174.0	2BT02@1|root,32N40@2|Bacteria,1Q3JG@1224|Proteobacteria,439CC@68525|delta/epsilon subdivisions,2X4KJ@28221|Deltaproteobacteria,2Z05X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
REGS1_k127_7710720_6	290397.Adeh_3333	3.145e-118	386.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_3333|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7710720_2	1297742.A176_06696	1.382e-160	522.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42ZC3@68525|delta/epsilon subdivisions,2WTR3@28221|Deltaproteobacteria,2YYR2@29|Myxococcales	28221|Deltaproteobacteria	KT	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
REGS1_k127_7710720_12	290397.Adeh_3335	9.45e-53	192.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
REGS1_k127_7710720_7	404589.Anae109_3402	8.66e-90	310.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
REGS1_k127_7710720_9	290397.Adeh_3337	6.584e-83	283.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
REGS1_k127_7710720_0	404589.Anae109_3405	0.0	1133.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Penicillin-binding protein, 1A family	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
REGS1_k127_7710720_5	404589.Anae109_0991	6.12e-129	428.0	COG0477@1|root,COG2814@2|Bacteria,1QUAS@1224|Proteobacteria,431FD@68525|delta/epsilon subdivisions,2WWTD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_7710720_4	290397.Adeh_0950	6.065e-136	467.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2YWF8@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
REGS1_k127_7710720_14	1408422.JHYF01000011_gene3388	8.085e-44	178.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,36ECS@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
REGS1_k127_7710720_22	243231.GSU1931	0.0001281	53.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,43UTI@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7710720_1	404589.Anae109_0986	3.075e-247	782.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
REGS1_k127_7710720_3	1242864.D187_004666	2.084e-157	515.0	COG0457@1|root,COG0457@2|Bacteria	1242864.D187_004666|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7710720_23	1146883.BLASA_2507	0.0009045	52.0	COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,2IC4C@201174|Actinobacteria,4ET06@85013|Frankiales	201174|Actinobacteria	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_19,HTH_3,HTH_31
REGS1_k127_7710720_16	1125863.JAFN01000001_gene1476	3.683e-37	150.0	COG1848@1|root,COG1848@2|Bacteria,1R1HG@1224|Proteobacteria	1224|Proteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_7710720_10	404589.Anae109_0979	3.714e-81	281.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,432T5@68525|delta/epsilon subdivisions,2WY30@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7710720_11	290397.Adeh_0937	5.755e-76	263.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,42U7W@68525|delta/epsilon subdivisions,2WQ9A@28221|Deltaproteobacteria,2YVEF@29|Myxococcales	28221|Deltaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
REGS1_k127_7710720_20	882.DVU_1367	3.469e-08	55.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,2MD43@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_7710720_8	290397.Adeh_0936	9.835e-85	293.0	2EI76@1|root,33BYI@2|Bacteria,1NMIN@1224|Proteobacteria,42XUD@68525|delta/epsilon subdivisions,2WSV6@28221|Deltaproteobacteria,2Z2Z6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7732971_4	290397.Adeh_1909	1.124e-60	213.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,2YV9J@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
REGS1_k127_7732971_8	404589.Anae109_1947	1.088e-33	144.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
REGS1_k127_7732971_0	290397.Adeh_1911	1.652e-196	630.0	COG0419@1|root,COG0419@2|Bacteria	2|Bacteria	L	ATPase involved in DNA repair	recF	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23
REGS1_k127_7732971_6	1232430.CAVG010000119_gene1144	2.339e-38	150.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli,4GZ4J@90964|Staphylococcaceae	91061|Bacilli	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
REGS1_k127_7732971_2	290397.Adeh_1913	6.396e-123	400.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,2YV3E@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
REGS1_k127_7732971_3	290397.Adeh_1914	5.149e-64	225.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,42TGI@68525|delta/epsilon subdivisions,2WQJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
REGS1_k127_7732971_9	404589.Anae109_1942	4.035e-33	133.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
REGS1_k127_7732971_7	404589.Anae109_1941	4.834e-37	142.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,2YVTF@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
REGS1_k127_7732971_5	404589.Anae109_1939	3.99e-51	185.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2Z32V@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
REGS1_k127_7732971_1	290397.Adeh_1919	2.731e-144	459.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2YXN1@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
REGS1_k127_7776470_2	931626.Awo_c33270	9.457e-07	60.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,2484V@186801|Clostridia,25VKA@186806|Eubacteriaceae	186801|Clostridia	E	YoaP-like	yoaP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
REGS1_k127_7776470_1	1121920.AUAU01000014_gene2811	8.8e-28	118.0	2E3B5@1|root,32YAP@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
REGS1_k127_7788407_5	1121920.AUAU01000026_gene1436	9.125e-66	229.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	COX3
REGS1_k127_7788407_10	1110502.TMO_1481	1.359e-08	60.0	2AK3H@1|root,31ATA@2|Bacteria,1Q63E@1224|Proteobacteria,2VCBM@28211|Alphaproteobacteria,2JYCP@204441|Rhodospirillales	204441|Rhodospirillales	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
REGS1_k127_7788407_3	1121920.AUAU01000026_gene1434	2.116e-88	301.0	COG1622@1|root,COG1622@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
REGS1_k127_7788407_8	903818.KI912268_gene1403	9.081e-43	179.0	COG0109@1|root,COG0109@2|Bacteria,3Y3VI@57723|Acidobacteria	57723|Acidobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	-	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
REGS1_k127_7788407_7	290397.Adeh_2989	9.707e-53	209.0	2E0UW@1|root,32WC8@2|Bacteria,1P2M6@1224|Proteobacteria,431CM@68525|delta/epsilon subdivisions,2WW9V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_7788407_1	404589.Anae109_0091	3.02e-221	696.0	COG0433@1|root,COG0433@2|Bacteria,1MU59@1224|Proteobacteria,42MTV@68525|delta/epsilon subdivisions,2WKVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF853)	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	DUF853,DUF87
REGS1_k127_7788407_6	1220534.B655_1034	3.728e-57	228.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_7788407_2	404589.Anae109_4186	2.509e-109	387.0	COG0642@1|root,COG2205@2|Bacteria,1QX6W@1224|Proteobacteria,42ZK5@68525|delta/epsilon subdivisions,2WUSH@28221|Deltaproteobacteria,2YXKX@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4
REGS1_k127_7788407_4	404589.Anae109_0090	6.917e-80	271.0	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria,2YVS1@29|Myxococcales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
REGS1_k127_7788407_0	404589.Anae109_4062	1.868e-318	979.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YUAB@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_7800655_0	404589.Anae109_3032	3.847e-175	558.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2WJ5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Sigma54_activat
REGS1_k127_7800655_1	452637.Oter_2465	8.958e-69	242.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,46VST@74201|Verrucomicrobia,3K7DE@414999|Opitutae	74201|Verrucomicrobia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	hycG	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
REGS1_k127_7809646_3	290397.Adeh_0186	1.309e-62	228.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2YVCP@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
REGS1_k127_7809646_2	290397.Adeh_0185	6.433e-88	309.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WNYG@28221|Deltaproteobacteria,2Z1BJ@29|Myxococcales	28221|Deltaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
REGS1_k127_7809646_0	404589.Anae109_0204	2.813e-216	693.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,42N01@68525|delta/epsilon subdivisions,2WKJQ@28221|Deltaproteobacteria,2YUM6@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
REGS1_k127_7809646_1	290397.Adeh_0183	1.505e-110	374.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,42MH0@68525|delta/epsilon subdivisions,2WRNN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
REGS1_k127_7809646_4	404589.Anae109_0201	3.044e-58	204.0	COG4401@1|root,COG4401@2|Bacteria,1NANV@1224|Proteobacteria,433PN@68525|delta/epsilon subdivisions,2WX99@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Chorismate mutase of the AroH class	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
REGS1_k127_7809646_5	1297742.A176_02835	3.187e-22	106.0	COG1994@1|root,COG1994@2|Bacteria,1Q2IJ@1224|Proteobacteria,433TS@68525|delta/epsilon subdivisions,2X3F7@28221|Deltaproteobacteria,2YVTY@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
REGS1_k127_7809935_2	1265505.ATUG01000001_gene4389	4.128e-28	120.0	COG1595@1|root,COG1595@2|Bacteria,1PEU8@1224|Proteobacteria,42T76@68525|delta/epsilon subdivisions,2WPVH@28221|Deltaproteobacteria,2MM35@213118|Desulfobacterales	28221|Deltaproteobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_7809935_1	316067.Geob_3762	7.363e-31	126.0	2E5QB@1|root,330EW@2|Bacteria,1N890@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2844
REGS1_k127_7809935_0	443144.GM21_2127	3.586e-108	366.0	COG5492@1|root,COG5492@2|Bacteria,1QYX0@1224|Proteobacteria	1224|Proteobacteria	N	Protein of unknown function (DUF3443)	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF3443
REGS1_k127_7809935_3	1089547.KB913013_gene2442	3.614e-13	77.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,47M7J@768503|Cytophagia	976|Bacteroidetes	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
REGS1_k127_7809935_4	596328.HMPREF0578_0023	0.0004084	48.0	COG1848@1|root,COG1848@2|Bacteria,2GRA5@201174|Actinobacteria,4D6JQ@85005|Actinomycetales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
REGS1_k127_7851220_2	1278073.MYSTI_07712	1.299e-59	232.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	peptidylprolyl isomerase, FKBP-type	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
REGS1_k127_7851220_0	404589.Anae109_3462	8.175e-131	428.0	COG0628@1|root,COG0628@2|Bacteria,1PTH3@1224|Proteobacteria,42T9W@68525|delta/epsilon subdivisions,2WPRE@28221|Deltaproteobacteria,2YUY8@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_7851220_1	290397.Adeh_3395	5.471e-118	405.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,42Q52@68525|delta/epsilon subdivisions,2WJ3S@28221|Deltaproteobacteria,2Z0HR@29|Myxococcales	28221|Deltaproteobacteria	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
REGS1_k127_79088_4	1232410.KI421420_gene3206	3.532e-06	55.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,42NE5@68525|delta/epsilon subdivisions,2WJ14@28221|Deltaproteobacteria,43SAX@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
REGS1_k127_79088_1	404589.Anae109_3024	1.413e-177	569.0	COG0535@1|root,COG0535@2|Bacteria,1MWDC@1224|Proteobacteria,42MHB@68525|delta/epsilon subdivisions,2WIPH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Radical_SAM
REGS1_k127_79088_3	987059.RBXJA2T_15683	3.984e-111	371.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,1KJKX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	I	Belongs to the thiolase family	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_79088_0	290397.Adeh_0358	1.604e-312	975.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MI5@68525|delta/epsilon subdivisions,2WITQ@28221|Deltaproteobacteria,2YU2Y@29|Myxococcales	28221|Deltaproteobacteria	I	3-hydroxyacyl-CoA dehydrogenase	-	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1,ECH_2
REGS1_k127_79088_2	290397.Adeh_1491	4.219e-159	505.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2Z2XY@29|Myxococcales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amt	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
REGS1_k127_7935907_4	404589.Anae109_1710	7.016e-44	161.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,42PQY@68525|delta/epsilon subdivisions,2WJXE@28221|Deltaproteobacteria,2YUH0@29|Myxococcales	28221|Deltaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
REGS1_k127_7935907_2	404589.Anae109_2981	9.131e-100	337.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42RCZ@68525|delta/epsilon subdivisions,2WN2W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
REGS1_k127_7935907_0	404589.Anae109_2982	0.0	1350.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
REGS1_k127_7935907_3	338969.Rfer_3394	5.227e-75	265.0	COG3115@1|root,COG3115@2|Bacteria,1QWGJ@1224|Proteobacteria,2WGZ3@28216|Betaproteobacteria,4AH94@80864|Comamonadaceae	28216|Betaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7935907_1	338966.Ppro_2064	0.0	1069.0	28HB2@1|root,2Z7N8@2|Bacteria,1P4RV@1224|Proteobacteria,42NVF@68525|delta/epsilon subdivisions,2WKNV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Fatty acid cis/trans isomerase (CTI)	-	-	-	-	-	-	-	-	-	-	-	-	CTI
REGS1_k127_7949715_0	290397.Adeh_1265	1.712e-228	714.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2YUGA@29|Myxococcales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
REGS1_k127_7949715_1	404589.Anae109_2505	6.361e-154	492.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,42MK1@68525|delta/epsilon subdivisions,2WK5D@28221|Deltaproteobacteria,2Z2YR@29|Myxococcales	28221|Deltaproteobacteria	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
REGS1_k127_7949715_4	5270.UM05072P0	1.229e-16	95.0	295V2@1|root,2RCTN@2759|Eukaryota,3AYV0@33154|Opisthokonta,3PJYM@4751|Fungi,3V9DV@5204|Basidiomycota,3N0CW@452284|Ustilaginomycotina	4751|Fungi	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7949715_3	1245471.PCA10_00940	9.188e-28	125.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,1RWCX@1236|Gammaproteobacteria,1YERG@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_7949715_2	290397.Adeh_1260	3.201e-45	173.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA_C
REGS1_k127_7970582_1	903818.KI912268_gene1854	1.414e-193	649.0	28JHJ@1|root,2Z9B3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7970582_3	290397.Adeh_0861	2.693e-118	415.0	COG3482@1|root,COG3482@2|Bacteria,1N2YR@1224|Proteobacteria,430MW@68525|delta/epsilon subdivisions,2WVPD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TfuA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TfuA
REGS1_k127_7970582_4	404589.Anae109_0919	5.564e-101	364.0	COG1944@1|root,COG1944@2|Bacteria	2|Bacteria	S	ATP diphosphatase activity	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	YcaO
REGS1_k127_7970582_2	243231.GSU3087	5.917e-119	392.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42MFD@68525|delta/epsilon subdivisions,2WM9M@28221|Deltaproteobacteria,43S95@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sir2 family	srtN	-	-	-	-	-	-	-	-	-	-	-	SIR2
REGS1_k127_7970582_13	883.DvMF_2107	6.552e-20	94.0	COG0466@1|root,COG0466@2|Bacteria,1R6HF@1224|Proteobacteria,42QHZ@68525|delta/epsilon subdivisions,2WJNZ@28221|Deltaproteobacteria,2M8MA@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	response regulator, receiver	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,Lon_C,Response_reg
REGS1_k127_7970582_15	596153.Alide_3355	0.0003269	53.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,4ACNP@80864|Comamonadaceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
REGS1_k127_7970582_14	388051.AUFE01000059_gene6153	3.245e-08	66.0	COG1388@1|root,COG4254@1|root,COG1388@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VR04@28216|Betaproteobacteria,1KH4M@119060|Burkholderiaceae	28216|Betaproteobacteria	M	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
REGS1_k127_7970582_7	443143.GM18_2583	3.77e-76	284.0	COG4191@1|root,COG4191@2|Bacteria,1MY12@1224|Proteobacteria,42PID@68525|delta/epsilon subdivisions,2WJVW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
REGS1_k127_7970582_12	903818.KI912269_gene368	2.108e-28	127.0	COG1512@1|root,COG1512@2|Bacteria,3Y4JT@57723|Acidobacteria	57723|Acidobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
REGS1_k127_7970582_9	29306.JOBE01000001_gene2614	6.003e-64	233.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
REGS1_k127_7970582_6	404589.Anae109_1741	1.726e-79	276.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,42RNH@68525|delta/epsilon subdivisions,2X5NY@28221|Deltaproteobacteria,2Z0TQ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
REGS1_k127_7970582_0	404589.Anae109_0921	0.0	1364.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,2YUIS@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_7970582_8	404589.Anae109_0924	8.672e-73	278.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,2Z24Q@29|Myxococcales	28221|Deltaproteobacteria	S	LemA family	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
REGS1_k127_7970582_10	404589.Anae109_0925	5.102e-62	231.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria,2YW48@29|Myxococcales	28221|Deltaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
REGS1_k127_7970582_5	404589.Anae109_0926	4.478e-83	280.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,42QZE@68525|delta/epsilon subdivisions,2WS8W@28221|Deltaproteobacteria,2YW5B@29|Myxococcales	28221|Deltaproteobacteria	S	Membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
REGS1_k127_7970582_16	1237149.C900_05014	0.0004922	51.0	2DQF9@1|root,336H4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7970582_11	404589.Anae109_0928	4.778e-35	136.0	COG0535@1|root,COG0535@2|Bacteria,1R4I0@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
REGS1_k127_7989864_1	215803.DB30_2637	2.114e-135	440.0	COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,1QTSD@1224|Proteobacteria,42QG4@68525|delta/epsilon subdivisions,2WKK8@28221|Deltaproteobacteria,2YTX2@29|Myxococcales	28221|Deltaproteobacteria	P	TrkA-C domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C
REGS1_k127_7989864_3	246197.MXAN_1917	6.241e-18	95.0	2A45D@1|root,30SQF@2|Bacteria,1PC1Y@1224|Proteobacteria,43879@68525|delta/epsilon subdivisions,2X3H7@28221|Deltaproteobacteria,2YW2Q@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7989864_2	290397.Adeh_2375	1.168e-44	180.0	arCOG09455@1|root,2ZPCS@2|Bacteria,1NPCM@1224|Proteobacteria,42XA8@68525|delta/epsilon subdivisions,2WT3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7989864_6	292415.Tbd_2111	2.338e-07	61.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VT0X@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_7989864_0	404589.Anae109_1629	8.365e-175	578.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
REGS1_k127_7989864_5	1144275.COCOR_02346	4.01e-11	68.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,2YVF4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
REGS1_k127_7995866_11	404589.Anae109_3900	1.757e-60	218.0	2EGEF@1|root,33A6F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7995866_14	443144.GM21_0880	1.286e-54	207.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
REGS1_k127_7995866_16	589865.DaAHT2_2268	7.212e-43	168.0	COG0457@1|root,COG0457@2|Bacteria,1NYJF@1224|Proteobacteria	1224|Proteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7995866_13	1123371.ATXH01000008_gene269	1.194e-54	210.0	COG4885@1|root,COG4885@2|Bacteria	2|Bacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT,Cytochrome_C554
REGS1_k127_7995866_15	404589.Anae109_3444	2.703e-47	198.0	COG4885@1|root,COG4885@2|Bacteria,1R65B@1224|Proteobacteria,42P8E@68525|delta/epsilon subdivisions,2WIXT@28221|Deltaproteobacteria,2Z3J1@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554
REGS1_k127_7995866_19	646529.Desaci_2001	1.825e-21	108.0	2A154@1|root,30PAZ@2|Bacteria,1V68U@1239|Firmicutes,24J10@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
REGS1_k127_7995866_10	338966.Ppro_2994	5.981e-63	226.0	2CCV8@1|root,2Z7KX@2|Bacteria,1MY2J@1224|Proteobacteria,42PUV@68525|delta/epsilon subdivisions,2WKCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
REGS1_k127_7995866_17	290397.Adeh_3409	8.983e-40	161.0	COG1186@1|root,COG1186@2|Bacteria,1ND5C@1224|Proteobacteria,430VS@68525|delta/epsilon subdivisions,2WW3U@28221|Deltaproteobacteria,2Z2GT@29|Myxococcales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
REGS1_k127_7995866_6	290397.Adeh_3410	2.968e-102	337.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2YUSX@29|Myxococcales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
REGS1_k127_7995866_3	290397.Adeh_3411	9.188e-161	516.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2YTZ7@29|Myxococcales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
REGS1_k127_7995866_8	215803.DB30_2305	3.399e-82	288.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2X36X@28221|Deltaproteobacteria,2YUQM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
REGS1_k127_7995866_7	290397.Adeh_3418	2.076e-88	306.0	COG0500@1|root,COG2226@2|Bacteria,1REKQ@1224|Proteobacteria,43AKZ@68525|delta/epsilon subdivisions,2X614@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_7995866_9	290397.Adeh_2415	1.856e-67	235.0	COG1595@1|root,COG1595@2|Bacteria,1N298@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
REGS1_k127_7995866_0	290397.Adeh_2413	1.252e-213	677.0	COG4249@1|root,COG4249@2|Bacteria,1NJ33@1224|Proteobacteria,42PEW@68525|delta/epsilon subdivisions,2WSC3@28221|Deltaproteobacteria,2YZJG@29|Myxococcales	28221|Deltaproteobacteria	T	protein containing caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,TIR_2,WD40
REGS1_k127_7995866_20	215803.DB30_7828	9.932e-11	76.0	2BSKW@1|root,32MPF@2|Bacteria,1Q3C8@1224|Proteobacteria,4393K@68525|delta/epsilon subdivisions,2X49I@28221|Deltaproteobacteria,2YYJF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7995866_2	404589.Anae109_3481	7.457e-162	542.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,42RUS@68525|delta/epsilon subdivisions,2WNWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidogalycan biosysnthesis/recognition	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
REGS1_k127_7995866_1	290397.Adeh_3749	3.209e-163	518.0	COG0715@1|root,COG0715@2|Bacteria,1MZ8F@1224|Proteobacteria,42Q55@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	PFAM NMT1 THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
REGS1_k127_7995866_4	290397.Adeh_3750	1.321e-126	431.0	COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,43AF8@68525|delta/epsilon subdivisions,2X607@28221|Deltaproteobacteria,2Z387@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
REGS1_k127_7995866_5	290397.Adeh_3751	6.529e-126	417.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2WMNQ@28221|Deltaproteobacteria,2YYGC@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter, ATP-binding protein	-	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
REGS1_k127_8032258_0	1411123.JQNH01000001_gene3830	1.916e-69	248.0	COG2801@1|root,COG2801@2|Bacteria,1MWNX@1224|Proteobacteria,2TZ7M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve,rve_3
REGS1_k127_8032258_1	43759.JNWK01000010_gene4797	6.543e-05	49.0	2AN3R@1|root,31D1D@2|Bacteria,2ISC8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_80351_1	404589.Anae109_4497	1.367e-296	913.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2YUF7@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
REGS1_k127_80351_3	404589.Anae109_4496	3.172e-146	467.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2YUV1@29|Myxococcales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
REGS1_k127_80351_2	404589.Anae109_4495	9.599e-274	872.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2YU1A@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
REGS1_k127_80351_4	404589.Anae109_4494	3.556e-69	235.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2YW5U@29|Myxococcales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
REGS1_k127_80351_5	215803.DB30_0461	1.206e-41	170.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,43BK1@68525|delta/epsilon subdivisions,2X6XW@28221|Deltaproteobacteria,2YZAU@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
REGS1_k127_80351_0	404589.Anae109_4493	0.0	1101.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2YUDT@29|Myxococcales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
REGS1_k127_8077291_1	404589.Anae109_0666	7.225e-119	387.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2YV5E@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
REGS1_k127_8077291_0	290397.Adeh_0622	2.614e-318	986.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YTYC@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
REGS1_k127_8077291_2	290397.Adeh_0623	1.207e-64	222.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YWXD@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_8098659_6	316067.Geob_0814	3.454e-14	88.0	COG1361@1|root,COG1520@1|root,COG1657@1|root,COG4257@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1657@2|Bacteria,COG4257@2|Bacteria,COG4733@2|Bacteria,1QYWJ@1224|Proteobacteria,43CDC@68525|delta/epsilon subdivisions,2X7P6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
REGS1_k127_8098659_5	404589.Anae109_1170	1.185e-29	123.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YUJ6@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
REGS1_k127_8098659_1	290397.Adeh_0090	1.569e-86	303.0	COG0642@1|root,COG2205@2|Bacteria	290397.Adeh_0090|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8098659_3	404589.Anae109_1163	6.28e-69	235.0	COG1051@1|root,COG1051@2|Bacteria,1QUM0@1224|Proteobacteria,42SY6@68525|delta/epsilon subdivisions,2WP3N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
REGS1_k127_8098659_2	404589.Anae109_1162	1.044e-72	251.0	COG2078@1|root,COG2078@2|Bacteria,1RJP4@1224|Proteobacteria,42SBG@68525|delta/epsilon subdivisions,2WP66@28221|Deltaproteobacteria,2YVPM@29|Myxococcales	28221|Deltaproteobacteria	S	AMMECR1	-	-	-	ko:K09141	-	-	-	-	ko00000	-	-	-	AMMECR1
REGS1_k127_8098659_4	290397.Adeh_1121	1.417e-58	212.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YV9N@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
REGS1_k127_8100244_3	1120966.AUBU01000001_gene1081	9.33e-47	186.0	COG2080@1|root,COG2080@2|Bacteria,4NM72@976|Bacteroidetes,47PA8@768503|Cytophagia	976|Bacteroidetes	C	2Fe-2S -binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
REGS1_k127_8100244_0	290397.Adeh_3104	2.322e-129	434.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2WMVP@28221|Deltaproteobacteria,2YYXW@29|Myxococcales	28221|Deltaproteobacteria	O	XdhC Rossmann domain	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3,XdhC_C,XdhC_CoxI
REGS1_k127_8100244_2	290397.Adeh_3105	1.219e-66	234.0	COG2068@1|root,COG2068@2|Bacteria	2|Bacteria	NU	MobA-Related Protein	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
REGS1_k127_8100244_1	404589.Anae109_0510	2.366e-119	395.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,4320Q@68525|delta/epsilon subdivisions,2WWCH@28221|Deltaproteobacteria,2YX5N@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_8102794_8	290397.Adeh_4229	6.171e-33	128.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YWPQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
REGS1_k127_8102794_1	404589.Anae109_4378	1.735e-170	541.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42MYT@68525|delta/epsilon subdivisions,2WM6R@28221|Deltaproteobacteria,2YZCT@29|Myxococcales	28221|Deltaproteobacteria	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
REGS1_k127_8102794_2	290397.Adeh_4227	3.884e-102	336.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,2Z0HM@29|Myxococcales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
REGS1_k127_8102794_7	404589.Anae109_4369	2.545e-34	147.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Smr protein MutS2	-	-	-	-	-	-	-	-	-	-	-	-	Smr
REGS1_k127_8102794_5	404589.Anae109_4368	3.604e-69	243.0	COG0671@1|root,COG0671@2|Bacteria,1RIRR@1224|Proteobacteria,42X79@68525|delta/epsilon subdivisions,2WXA0@28221|Deltaproteobacteria,2YVD9@29|Myxococcales	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_8102794_0	290397.Adeh_4216	1.5e-267	838.0	COG1112@1|root,COG1198@1|root,COG1112@2|Bacteria,COG1198@2|Bacteria,1MWW9@1224|Proteobacteria,43BG9@68525|delta/epsilon subdivisions,2WQHZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	AAA domain	-	-	3.6.4.12	ko:K10742	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	AAA_11,AAA_12
REGS1_k127_8102794_3	404589.Anae109_4365	8.248e-102	365.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CCK@68525|delta/epsilon subdivisions,2X7Q6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA,PAS_4,PAS_9
REGS1_k127_8102794_6	1192034.CAP_5182	5.95e-51	193.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_8102794_4	404589.Anae109_4364	1.089e-97	331.0	COG3359@1|root,COG3359@2|Bacteria,1R6A2@1224|Proteobacteria,42MVN@68525|delta/epsilon subdivisions,2WK0C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
REGS1_k127_8123114_4	290397.Adeh_1086	6.004e-137	439.0	COG3494@1|root,COG3494@2|Bacteria,1MWTH@1224|Proteobacteria,42P40@68525|delta/epsilon subdivisions,2WK7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
REGS1_k127_8123114_5	290397.Adeh_1087	5.393e-34	145.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,2YW4H@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
REGS1_k127_8123114_2	290397.Adeh_1088	7.546e-185	585.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2YTSB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
REGS1_k127_8123114_0	290397.Adeh_1089	6.434e-252	801.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,42M87@68525|delta/epsilon subdivisions,2WMB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_8123114_3	404589.Anae109_1130	1.788e-141	477.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,2Z21X@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
REGS1_k127_8123114_1	290397.Adeh_1091	2.874e-228	722.0	COG0457@1|root,COG0484@1|root,COG0457@2|Bacteria,COG0484@2|Bacteria,1NX2M@1224|Proteobacteria	1224|Proteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DUF4388,DnaJ,Response_reg,TPR_2
REGS1_k127_8129103_8	215803.DB30_5463	4.425e-19	96.0	COG0457@1|root,COG0664@1|root,COG0457@2|Bacteria,COG0664@2|Bacteria,1N1ZG@1224|Proteobacteria,4336W@68525|delta/epsilon subdivisions,2WYCK@28221|Deltaproteobacteria,2YXD4@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_8129103_5	404589.Anae109_2123	4.986e-116	410.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,Trypsin_2
REGS1_k127_8129103_4	404589.Anae109_2122	1.79e-120	402.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2YUXM@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_8129103_3	404589.Anae109_2121	7.11e-123	424.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,2Z010@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
REGS1_k127_8129103_2	290397.Adeh_1684	2.004e-139	448.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2YV06@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
REGS1_k127_8129103_0	404589.Anae109_2119	2.161e-182	578.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,2YV60@29|Myxococcales	28221|Deltaproteobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
REGS1_k127_8129103_7	290397.Adeh_1686	1.021e-56	218.0	COG1994@1|root,COG1994@2|Bacteria,1PI96@1224|Proteobacteria,43A6G@68525|delta/epsilon subdivisions,2X25Z@28221|Deltaproteobacteria,2Z1TG@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
REGS1_k127_8129103_1	290397.Adeh_1687	1.09e-142	458.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2YWUR@29|Myxococcales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_8129103_6	404589.Anae109_2116	9.633e-115	371.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,2YVAC@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	yrdC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
REGS1_k127_8129103_9	214092.YPO2853	9.259e-15	81.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,1RMD0@1236|Gammaproteobacteria,41E17@629|Yersinia	1236|Gammaproteobacteria	K	Transcriptional regulatory protein, C terminal	baeR	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001023,GO:2001141	-	ko:K07664,ko:K18144	ko01501,ko02020,map01501,map02020	M00450,M00645,M00646,M00648,M00649,M00655	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_813677_0	404589.Anae109_1294	2.544e-238	745.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WKMJ@28221|Deltaproteobacteria,2YU8F@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
REGS1_k127_813677_1	404589.Anae109_1295	1.673e-177	569.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YUQD@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
REGS1_k127_813677_3	290397.Adeh_2564	4.076e-107	354.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2WRSP@28221|Deltaproteobacteria,2Z31G@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
REGS1_k127_813677_2	404589.Anae109_1297	2.345e-129	426.0	2F8HZ@1|root,340WS@2|Bacteria,1NJHM@1224|Proteobacteria,430Z9@68525|delta/epsilon subdivisions,2WVPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8148030_13	404589.Anae109_3447	1.13e-47	181.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8148030_5	290397.Adeh_3383	1.266e-154	525.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria,2Z0GM@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
REGS1_k127_8148030_6	290397.Adeh_3382	3.068e-122	406.0	COG3850@1|root,COG3850@2|Bacteria,1N013@1224|Proteobacteria,42Z7D@68525|delta/epsilon subdivisions,2WURU@28221|Deltaproteobacteria	1224|Proteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
REGS1_k127_8148030_1	290397.Adeh_3381	0.0	1249.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42PZF@68525|delta/epsilon subdivisions,2X5HR@28221|Deltaproteobacteria,2YYCV@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_8148030_0	404589.Anae109_3793	0.0	1362.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,2YU96@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
REGS1_k127_8148030_14	404589.Anae109_0548	1.027e-22	103.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	GGDEF,Guanylate_cyc,Hemerythrin,NIT
REGS1_k127_8148030_3	290397.Adeh_1659	4.571e-175	561.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
REGS1_k127_8148030_2	404589.Anae109_0984	1.418e-288	900.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,42MP3@68525|delta/epsilon subdivisions,2WJ7Y@28221|Deltaproteobacteria,2YX41@29|Myxococcales	28221|Deltaproteobacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	GlcNAc_2-epim,Thioredox_DsbH
REGS1_k127_8148030_8	1121918.ARWE01000001_gene3572	1.261e-90	336.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,43DDR@68525|delta/epsilon subdivisions,2X8JR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
REGS1_k127_8148030_9	404589.Anae109_0969	1.453e-83	290.0	COG0457@1|root,COG0457@2|Bacteria	404589.Anae109_0969|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8148030_4	290397.Adeh_0928	1.501e-158	523.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
REGS1_k127_8148030_7	290397.Adeh_0929	3.576e-117	386.0	COG0003@1|root,COG0003@2|Bacteria,1NA7C@1224|Proteobacteria,42V2J@68525|delta/epsilon subdivisions,2WS25@28221|Deltaproteobacteria,2YUZS@29|Myxococcales	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
REGS1_k127_8148030_11	290397.Adeh_0934	2.144e-56	203.0	COG5394@1|root,COG5394@2|Bacteria,1RHRC@1224|Proteobacteria,42WB9@68525|delta/epsilon subdivisions,2WSSJ@28221|Deltaproteobacteria,2YVJB@29|Myxococcales	28221|Deltaproteobacteria	S	PHB/PHA accumulation regulator DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PHB_acc_N
REGS1_k127_8148030_12	290397.Adeh_0935	5.956e-49	193.0	2AKQ6@1|root,31BGX@2|Bacteria,1RCS3@1224|Proteobacteria,43CC0@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
REGS1_k127_8152981_0	404589.Anae109_0770	1.238e-210	663.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2YU5P@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
REGS1_k127_8152981_4	313606.M23134_00497	5.805e-28	124.0	2DFQD@1|root,2ZSNM@2|Bacteria,4P7GE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8152981_1	290397.Adeh_1129	1.669e-124	415.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
REGS1_k127_8152981_2	290397.Adeh_2428	8.729e-115	373.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2YV0S@29|Myxococcales	28221|Deltaproteobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
REGS1_k127_8152981_3	404589.Anae109_1452	2.603e-109	357.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria,2Z08T@29|Myxococcales	28221|Deltaproteobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_8152981_5	404589.Anae109_1453	1.555e-11	66.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_8182255_8	1173264.KI913949_gene3050	2.184e-26	117.0	2CAI9@1|root,32RRG@2|Bacteria,1G7V1@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8182255_9	13035.Dacsa_0250	9.105e-12	70.0	2EBQI@1|root,335QJ@2|Bacteria,1G9WW@1117|Cyanobacteria	1117|Cyanobacteria	S	Protein of unknown function (DUF2283)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2283
REGS1_k127_8182255_0	404589.Anae109_0939	0.0	1107.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42U99@68525|delta/epsilon subdivisions,2WQ5W@28221|Deltaproteobacteria,2YWMR@29|Myxococcales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase domain protein	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
REGS1_k127_8182255_2	404589.Anae109_0938	1.182e-107	361.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,42RD5@68525|delta/epsilon subdivisions,2WMZ1@28221|Deltaproteobacteria,2YWME@29|Myxococcales	28221|Deltaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
REGS1_k127_8182255_10	1125699.HMPREF9194_01477	4.381e-08	66.0	2EW9A@1|root,33PN0@2|Bacteria,2J6QJ@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_8182255_7	1121920.AUAU01000011_gene207	3.49e-30	132.0	COG4235@1|root,COG4235@2|Bacteria,3Y8SD@57723|Acidobacteria	57723|Acidobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8182255_1	269799.Gmet_0208	2.016e-175	567.0	2C19K@1|root,33PMS@2|Bacteria,1NSP6@1224|Proteobacteria,42YKB@68525|delta/epsilon subdivisions,2WTSZ@28221|Deltaproteobacteria,43TR8@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8182255_5	316067.Geob_1125	1.944e-62	218.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,43UZ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
REGS1_k127_8182255_4	404589.Anae109_3503	3.915e-83	286.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,4330X@68525|delta/epsilon subdivisions,2WXN7@28221|Deltaproteobacteria,2Z0X5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8182255_6	382464.ABSI01000020_gene118	2.413e-31	136.0	COG3878@1|root,COG3878@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963
REGS1_k127_8182255_3	1122603.ATVI01000005_gene3835	1.826e-95	326.0	COG3946@1|root,COG3946@2|Bacteria,1R7R5@1224|Proteobacteria,1RS2B@1236|Gammaproteobacteria,1XBZD@135614|Xanthomonadales	135614|Xanthomonadales	U	Bacterial virulence protein (VirJ)	-	-	-	-	-	-	-	-	-	-	-	-	VirJ
REGS1_k127_8203966_0	290397.Adeh_2108	8.199e-172	541.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,42PQY@68525|delta/epsilon subdivisions,2WJXE@28221|Deltaproteobacteria,2YUH0@29|Myxococcales	28221|Deltaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
REGS1_k127_8203966_1	290397.Adeh_3162	6.825e-163	546.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
REGS1_k127_8224697_0	290397.Adeh_0641	5.995e-153	486.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
REGS1_k127_8224697_4	404589.Anae109_0687	3.004e-50	197.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria,2Z2I6@29|Myxococcales	28221|Deltaproteobacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
REGS1_k127_8224697_2	404589.Anae109_0688	4.756e-78	265.0	COG3167@1|root,COG3167@2|Bacteria,1MZZ4@1224|Proteobacteria,43B6P@68525|delta/epsilon subdivisions,2X6K9@28221|Deltaproteobacteria,2Z3BJ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein M subtype b	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
REGS1_k127_8224697_3	404589.Anae109_0689	1.228e-63	223.0	COG3168@1|root,COG3168@2|Bacteria,1N39F@1224|Proteobacteria,42U30@68525|delta/epsilon subdivisions,2WQFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	-	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
REGS1_k127_8224697_1	404589.Anae109_0690	2.493e-124	415.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
REGS1_k127_8241741_0	290397.Adeh_1544	4.57e-103	343.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WWTI@28221|Deltaproteobacteria,2Z314@29|Myxococcales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
REGS1_k127_8241741_3	404589.Anae109_2272	2.442e-85	290.0	COG0529@1|root,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,42ZXZ@68525|delta/epsilon subdivisions,2WVI7@28221|Deltaproteobacteria,2YV2C@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
REGS1_k127_8241741_4	404589.Anae109_2273	3.367e-60	216.0	COG0476@1|root,COG0476@2|Bacteria,1PDDQ@1224|Proteobacteria,435G7@68525|delta/epsilon subdivisions,2WZTP@28221|Deltaproteobacteria,2Z2QN@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	-	-	-	-	-	-	-	-	-	-	-	-	ThiF
REGS1_k127_8241741_2	404589.Anae109_2275	1.279e-87	295.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	-	-	2.7.7.80,2.8.1.11	ko:K21029,ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
REGS1_k127_8272918_1	290397.Adeh_2471	1.295e-129	424.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2WM5N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
REGS1_k127_8272918_0	290397.Adeh_2475	9.863e-241	757.0	COG0312@1|root,COG0312@2|Bacteria,1Q3C0@1224|Proteobacteria,4393A@68525|delta/epsilon subdivisions,2X495@28221|Deltaproteobacteria,2YYIX@29|Myxococcales	28221|Deltaproteobacteria	S	peptidase U62 modulator of DNA gyrase	-	-	-	-	-	-	-	-	-	-	-	-	PmbA_TldD
REGS1_k127_8288457_18	404589.Anae109_3777	1.479e-20	98.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	zraR	-	-	ko:K10943	ko02020,ko05111,map02020,map05111	M00515	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_8288457_1	404589.Anae109_3781	1.573e-228	734.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria,2YXCK@29|Myxococcales	28221|Deltaproteobacteria	CP	Proton-conducting membrane transporter	ehrA-2	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
REGS1_k127_8288457_6	404589.Anae109_3782	5.777e-112	368.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,42NHI@68525|delta/epsilon subdivisions,2WJ3D@28221|Deltaproteobacteria,2Z0BP@29|Myxococcales	28221|Deltaproteobacteria	C	NADH dehydrogenase	ehrB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0374,iAF987.Gmet_2600	NADHdh
REGS1_k127_8288457_12	404589.Anae109_3783	1.495e-69	241.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,42NDW@68525|delta/epsilon subdivisions,2WMF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	hydrogenase 4 membrane	ehrC	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q2
REGS1_k127_8288457_3	404589.Anae109_3784	1.643e-181	579.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,2YZXM@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	ehrD	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
REGS1_k127_8288457_2	404589.Anae109_3785	6.798e-192	612.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,2YZIA@29|Myxococcales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
REGS1_k127_8288457_7	404589.Anae109_3786	2.193e-111	365.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WJX8@28221|Deltaproteobacteria,2YZYI@29|Myxococcales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	ehrS	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2596	Fer4,Fer4_7,Oxidored_q6
REGS1_k127_8288457_23	1304865.JAGF01000001_gene984	2.121e-08	64.0	292NE@1|root,2ZQ69@2|Bacteria,2I8AI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8288457_22	545694.TREPR_3723	2.008e-09	67.0	COG1848@1|root,COG1848@2|Bacteria,2JAPG@203691|Spirochaetes	203691|Spirochaetes	S	Large family of predicted nucleotide-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_8288457_21	316056.RPC_4173	2.319e-10	65.0	2AHTU@1|root,3186F@2|Bacteria,1NN1Q@1224|Proteobacteria,2UTGK@28211|Alphaproteobacteria,3K4KG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_8288457_8	290397.Adeh_2662	7.953e-85	290.0	COG3021@1|root,COG3021@2|Bacteria,1QAG3@1224|Proteobacteria,4352B@68525|delta/epsilon subdivisions,2WZDA@28221|Deltaproteobacteria,2Z1W0@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
REGS1_k127_8288457_24	202952.BBLI01000008_gene828	7.865e-05	48.0	2DTNT@1|root,33M3P@2|Bacteria,1NH3S@1224|Proteobacteria,1SGZB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8288457_20	404589.Anae109_0696	2.834e-12	76.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
REGS1_k127_8288457_0	269799.Gmet_0661	0.0	1718.0	COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
REGS1_k127_8288457_4	290397.Adeh_2676	4.991e-146	467.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,2YU6V@29|Myxococcales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
REGS1_k127_8288457_14	290397.Adeh_2677	1.965e-55	224.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42SDH@68525|delta/epsilon subdivisions,2WPPH@28221|Deltaproteobacteria,2Z333@29|Myxococcales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_8288457_25	7070.TC011986-PA	0.0001423	54.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta	33208|Metazoa	T	Calcium ion binding	dp	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA
REGS1_k127_8288457_9	404589.Anae109_2672	2.436e-84	290.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2WMK3@28221|Deltaproteobacteria,2YVG8@29|Myxococcales	28221|Deltaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
REGS1_k127_8288457_16	404589.Anae109_2673	3.568e-54	196.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K21449	-	-	-	-	ko00000,ko02000	1.B.40.2	-	-	Cytochrome_C554,DUF11,SLH
REGS1_k127_8288457_11	290397.Adeh_2684	1.203e-69	241.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,2YVGY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
REGS1_k127_8288457_5	879212.DespoDRAFT_03178	2.744e-123	421.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42YGZ@68525|delta/epsilon subdivisions,2WU75@28221|Deltaproteobacteria,2MMN6@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
REGS1_k127_8288457_15	290397.Adeh_2686	6.926e-55	197.0	COG2030@1|root,COG2030@2|Bacteria,1QXU8@1224|Proteobacteria,43C6S@68525|delta/epsilon subdivisions,2X7GZ@28221|Deltaproteobacteria,2YW6B@29|Myxococcales	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
REGS1_k127_8288457_10	290397.Adeh_2687	2.463e-71	247.0	COG2030@1|root,COG2030@2|Bacteria,1NPDF@1224|Proteobacteria	1224|Proteobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
REGS1_k127_8288457_19	234267.Acid_7735	1.646e-14	75.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_8297950_1	404589.Anae109_2878	2.184e-235	740.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M8C@68525|delta/epsilon subdivisions,2WJB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K02688	-	-	-	-	ko00000,ko03000	-	-	-	HTH_8,PAS,PrpR_N,Sigma54_activat
REGS1_k127_8297950_6	404589.Anae109_0875	1.623e-39	166.0	COG1595@1|root,COG1595@2|Bacteria,1RHSF@1224|Proteobacteria,438JV@68525|delta/epsilon subdivisions,2X3UH@28221|Deltaproteobacteria,2YX4W@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	HTH_24,Sigma70_r2,Sigma70_r4_2
REGS1_k127_8297950_5	215803.DB30_1553	8.759e-55	201.0	COG5662@1|root,COG5662@2|Bacteria,1Q39S@1224|Proteobacteria,4390Y@68525|delta/epsilon subdivisions,2X465@28221|Deltaproteobacteria,2YYC2@29|Myxococcales	28221|Deltaproteobacteria	K	AntiSigma factor	actD	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8297950_3	404589.Anae109_0877	6.624e-96	344.0	COG4249@1|root,COG4249@2|Bacteria,1QX7K@1224|Proteobacteria,43AHW@68525|delta/epsilon subdivisions,2X5Y0@28221|Deltaproteobacteria,2YZCA@29|Myxococcales	28221|Deltaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
REGS1_k127_8297950_2	290397.Adeh_3810	1.687e-227	734.0	COG0457@1|root,COG0457@2|Bacteria	290397.Adeh_3810|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8297950_4	580332.Slit_1110	1.131e-65	234.0	COG4848@1|root,COG4848@2|Bacteria,1NE0R@1224|Proteobacteria,2VXNW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0354 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1444
REGS1_k127_8297950_0	215803.DB30_7610	2.971e-246	806.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
REGS1_k127_8301512_2	234267.Acid_7735	2.839e-188	599.0	COG1032@1|root,COG1032@2|Bacteria,3Y4FB@57723|Acidobacteria	57723|Acidobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_8301512_5	404589.Anae109_2682	2.992e-84	288.0	2DHU7@1|root,300Z2@2|Bacteria,1Q940@1224|Proteobacteria,433U6@68525|delta/epsilon subdivisions,2X3GR@28221|Deltaproteobacteria,2YW0V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
REGS1_k127_8301512_0	290397.Adeh_2689	1.769e-300	947.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YTUT@29|Myxococcales	28221|Deltaproteobacteria	O	heat shock protein 70	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
REGS1_k127_8301512_4	290397.Adeh_2690	2.076e-85	294.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ,TPR_8
REGS1_k127_8301512_3	404589.Anae109_2685	5.374e-155	495.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,2YUVY@29|Myxococcales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_8301512_1	290397.Adeh_2692	8.1e-208	656.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2YTVG@29|Myxococcales	28221|Deltaproteobacteria	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
REGS1_k127_8301512_6	404589.Anae109_2689	3.571e-33	128.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2YV00@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_8303592_2	290397.Adeh_0414	1.698e-131	426.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YTXZ@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
REGS1_k127_8303592_0	404589.Anae109_4154	3.212e-211	668.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2YU3N@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
REGS1_k127_8303592_1	290397.Adeh_0417	5.182e-188	600.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_8303592_3	290397.Adeh_0418	4.445e-89	301.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
REGS1_k127_8304513_6	1394178.AWOO02000062_gene478	2.159e-48	181.0	COG1926@1|root,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4EJ2D@85012|Streptosporangiales	201174|Actinobacteria	Q	Phosphoribosyl transferase domain	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
REGS1_k127_8304513_7	290397.Adeh_4116	1.342e-27	116.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	repA	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,GerE,ParA,Replicase,Response_reg
REGS1_k127_8304513_2	290397.Adeh_3009	1.599e-305	944.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,2YWII@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
REGS1_k127_8304513_5	404589.Anae109_0589	4.766e-63	248.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
REGS1_k127_8304513_4	404589.Anae109_0590	4.606e-115	381.0	COG0702@1|root,COG0702@2|Bacteria,1PFUF@1224|Proteobacteria,42R6E@68525|delta/epsilon subdivisions,2WN7T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
REGS1_k127_8304513_0	290397.Adeh_3015	0.0	1926.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,43BKE@68525|delta/epsilon subdivisions,2X6YE@28221|Deltaproteobacteria,2YYQ8@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
REGS1_k127_8304513_1	290397.Adeh_3018	0.0	1883.0	COG0247@1|root,COG0277@1|root,COG1139@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,COG1139@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2YU4J@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
REGS1_k127_8304513_3	404589.Anae109_3000	8.938e-193	606.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,2YU75@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
REGS1_k127_8310394_0	502025.Hoch_3456	2.165e-114	377.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2YU7W@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
REGS1_k127_8310394_1	472759.Nhal_3806	2.615e-50	196.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,1S0GF@1236|Gammaproteobacteria,1X0AW@135613|Chromatiales	135613|Chromatiales	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
REGS1_k127_8310394_2	1123073.KB899244_gene351	1.062e-41	160.0	COG0457@1|root,COG0457@2|Bacteria,1N9D5@1224|Proteobacteria,1SAKR@1236|Gammaproteobacteria,1XATQ@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8325225_0	760568.Desku_1231	3.535e-82	284.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,260BA@186807|Peptococcaceae	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
REGS1_k127_8325225_1	1051632.TPY_3574	5.343e-61	224.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WCGV@538999|Clostridiales incertae sedis	186801|Clostridia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
REGS1_k127_8325225_2	103733.JNYO01000020_gene1890	2.618e-35	145.0	COG2188@1|root,COG2188@2|Bacteria,2IG6B@201174|Actinobacteria,4EC61@85010|Pseudonocardiales	201174|Actinobacteria	K	UTRA	yvoA	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
REGS1_k127_8325225_3	1048834.TC41_1567	4.693e-25	107.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli,2781D@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
REGS1_k127_8387042_6	404589.Anae109_4290	5.009e-119	397.0	COG0438@1|root,COG0438@2|Bacteria,1R3Q9@1224|Proteobacteria,42MQ2@68525|delta/epsilon subdivisions,2WM1F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_8387042_9	290397.Adeh_4148	2.76e-66	250.0	COG0558@1|root,COG0558@2|Bacteria,1N9TT@1224|Proteobacteria,42V2Q@68525|delta/epsilon subdivisions,2WRYY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_8387042_2	404589.Anae109_4291	8.844e-216	681.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,42NWK@68525|delta/epsilon subdivisions,2WM2T@28221|Deltaproteobacteria,2YYFZ@29|Myxococcales	28221|Deltaproteobacteria	I	synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
REGS1_k127_8387042_19	502025.Hoch_6865	0.0002942	53.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K01993,ko:K02022,ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_8387042_13	1242864.D187_008778	1.706e-41	176.0	COG2027@1|root,COG2027@2|Bacteria,1RKPD@1224|Proteobacteria,42S90@68525|delta/epsilon subdivisions,2WNM2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460
REGS1_k127_8387042_7	290397.Adeh_4158	1.937e-118	384.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2YV8J@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
REGS1_k127_8387042_12	74545.EU96_0960	7.266e-44	169.0	COG0221@1|root,COG0221@2|Bacteria	2|Bacteria	C	inorganic diphosphatase activity	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	ParBc_2,Pyrophosphatase
REGS1_k127_8387042_16	1499967.BAYZ01000105_gene3476	8.213e-22	106.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_8387042_18	1123487.KB892863_gene1911	8.416e-09	68.0	COG1730@1|root,COG1730@2|Bacteria,1R2N7@1224|Proteobacteria	1224|Proteobacteria	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8387042_11	404589.Anae109_4305	1.272e-48	198.0	COG0680@1|root,COG0680@2|Bacteria,1NGWH@1224|Proteobacteria	1224|Proteobacteria	C	TIGRFAM hydrogenase maturation protease	vhtD	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
REGS1_k127_8387042_1	290397.Adeh_4162	1.139e-221	734.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42N63@68525|delta/epsilon subdivisions,2WJPA@28221|Deltaproteobacteria,2Z31J@29|Myxococcales	28221|Deltaproteobacteria	C	Nickel-dependent hydrogenase	-	-	1.8.98.5	ko:K14126	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
REGS1_k127_8387042_4	404589.Anae109_4307	2.512e-181	595.0	COG1908@1|root,COG1941@1|root,COG1908@2|Bacteria,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42RG2@68525|delta/epsilon subdivisions,2WNG4@28221|Deltaproteobacteria,2Z32N@29|Myxococcales	28221|Deltaproteobacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD,Oxidored_q6
REGS1_k127_8387042_3	290397.Adeh_4164	7.133e-208	664.0	COG1148@1|root,COG1148@2|Bacteria,1QUMN@1224|Proteobacteria,43BMA@68525|delta/epsilon subdivisions,2X6ZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Pyr_redox_2
REGS1_k127_8387042_14	404589.Anae109_4309	2.832e-35	136.0	COG0425@1|root,COG0425@2|Bacteria,1P4MT@1224|Proteobacteria	1224|Proteobacteria	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
REGS1_k127_8387042_10	404589.Anae109_4310	4.193e-61	241.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2YVHR@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
REGS1_k127_8387042_8	404589.Anae109_4311	1.417e-82	280.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
REGS1_k127_8387042_0	404589.Anae109_4312	5.979e-265	822.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2YTW6@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
REGS1_k127_8387042_5	290397.Adeh_4168	7.871e-126	416.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_8387042_15	290397.Adeh_4169	1.792e-25	114.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
REGS1_k127_8419840_1	404589.Anae109_0048	5.217e-53	194.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,42TQF@68525|delta/epsilon subdivisions,2WQHJ@28221|Deltaproteobacteria,2Z109@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
REGS1_k127_8419840_0	404589.Anae109_0049	1.847e-124	404.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RCI@68525|delta/epsilon subdivisions,2WMYC@28221|Deltaproteobacteria,2YVA5@29|Myxococcales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	etfB	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
REGS1_k127_8419840_2	290397.Adeh_0049	4.237e-40	153.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2YUPZ@29|Myxococcales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
REGS1_k127_8430729_0	404589.Anae109_3413	1.655e-184	579.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2YTVB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
REGS1_k127_8430729_4	290397.Adeh_3343	8.112e-89	313.0	COG3266@1|root,COG3266@2|Bacteria,1PBVF@1224|Proteobacteria,4384T@68525|delta/epsilon subdivisions,2X3EV@28221|Deltaproteobacteria,2YVRI@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
REGS1_k127_8430729_8	78398.KS43_18270	6.486e-23	107.0	2DNKZ@1|root,32Y1N@2|Bacteria,1RGGB@1224|Proteobacteria,1S5TA@1236|Gammaproteobacteria,1MT1R@122277|Pectobacterium	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2750)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2750
REGS1_k127_8430729_7	1242864.D187_007100	1.426e-45	171.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2WPSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
REGS1_k127_8430729_6	290397.Adeh_0951	2.654e-70	242.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
REGS1_k127_8430729_5	404589.Anae109_0993	8.057e-77	278.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,2Z0ZS@29|Myxococcales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
REGS1_k127_8430729_1	404589.Anae109_2163	3.346e-171	545.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,42MK5@68525|delta/epsilon subdivisions,2WJ3Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	acyl-coa dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_8430729_2	404589.Anae109_1505	1.215e-103	341.0	COG1788@1|root,COG1788@2|Bacteria,1MVEI@1224|Proteobacteria,42QMC@68525|delta/epsilon subdivisions,2WMDH@28221|Deltaproteobacteria,2YU4I@29|Myxococcales	28221|Deltaproteobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit	scoA	-	2.8.3.5	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
REGS1_k127_8430729_3	290397.Adeh_2363	2.228e-100	347.0	COG2057@1|root,COG2057@2|Bacteria,1RA4V@1224|Proteobacteria,42PZY@68525|delta/epsilon subdivisions,2WJ9V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit	scoB	-	2.8.3.5	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	-	R00410	RC00014	ko00000,ko00001,ko01000	-	-	-	CoA_trans
REGS1_k127_8440194_3	290397.Adeh_4037	5.251e-53	193.0	COG2030@1|root,COG2030@2|Bacteria,1RD6F@1224|Proteobacteria	1224|Proteobacteria	I	Dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
REGS1_k127_8440194_1	290397.Adeh_4036	1.454e-63	238.0	COG0457@1|root,COG0457@2|Bacteria,1QASR@1224|Proteobacteria,4359Y@68525|delta/epsilon subdivisions,2WZM1@28221|Deltaproteobacteria,2Z2CS@29|Myxococcales	28221|Deltaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
REGS1_k127_8440194_6	56780.SYN_01583	8.72e-18	90.0	2AVTU@1|root,31MME@2|Bacteria,1NQ7V@1224|Proteobacteria,42XCN@68525|delta/epsilon subdivisions,2WTFJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8440194_0	290397.Adeh_4035	2.604e-68	249.0	COG2834@1|root,COG2834@2|Bacteria,1NMTC@1224|Proteobacteria,42XC3@68525|delta/epsilon subdivisions,2WT97@28221|Deltaproteobacteria,2YWF6@29|Myxococcales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
REGS1_k127_8440194_2	290397.Adeh_4034	1.039e-59	213.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,42YY2@68525|delta/epsilon subdivisions,2WUI6@28221|Deltaproteobacteria,2Z0E8@29|Myxococcales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
REGS1_k127_8440194_5	404589.Anae109_0395	2.602e-40	170.0	COG0848@1|root,COG0848@2|Bacteria,1Q5DA@1224|Proteobacteria,42VMC@68525|delta/epsilon subdivisions,2X5N3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Biopolymer transport protein	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
REGS1_k127_8440194_4	290397.Adeh_4032	1.061e-43	162.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
REGS1_k127_8451389_0	1123354.AUDR01000013_gene638	6.195e-20	105.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,1KRY5@119069|Hydrogenophilales	119069|Hydrogenophilales	U	TolB amino-terminal domain	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
REGS1_k127_8451389_1	1232410.KI421428_gene968	4.109e-09	68.0	COG0535@1|root,COG0535@2|Bacteria,1R58E@1224|Proteobacteria,42NSA@68525|delta/epsilon subdivisions,2WPAQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
REGS1_k127_8451389_5	1123258.AQXZ01000009_gene1436	1.375e-05	58.0	2DR31@1|root,339YG@2|Bacteria	2|Bacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
REGS1_k127_8451389_3	525904.Tter_2793	4.839e-06	60.0	2BHGH@1|root,32BIN@2|Bacteria,2NRSQ@2323|unclassified Bacteria	2|Bacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
REGS1_k127_8451389_4	1268072.PSAB_04130	6.344e-06	58.0	COG1493@1|root,COG1493@2|Bacteria,1V4IV@1239|Firmicutes,4HGBQ@91061|Bacilli,26SXR@186822|Paenibacillaceae	91061|Bacilli	T	Serine kinase of the HPr protein, regulates carbohydrate metabolism	hprK3	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,Hpr_kinase_C
REGS1_k127_8455098_1	234267.Acid_5684	7.475e-78	265.0	COG0649@1|root,COG0649@2|Bacteria,3Y3AB@57723|Acidobacteria	57723|Acidobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
REGS1_k127_8455098_0	1162668.LFE_1693	1.463e-91	311.0	COG1005@1|root,COG1005@2|Bacteria,3J0E2@40117|Nitrospirae	40117|Nitrospirae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
REGS1_k127_8457125_1	290397.Adeh_3793	1.045e-217	685.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,42QDI@68525|delta/epsilon subdivisions,2WJMG@28221|Deltaproteobacteria,2YWDT@29|Myxococcales	28221|Deltaproteobacteria	H	glutamate--cysteine ligase	-	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
REGS1_k127_8457125_3	1347086.CCBA010000039_gene4932	1.7e-52	195.0	COG2110@1|root,COG2110@2|Bacteria,1VJBF@1239|Firmicutes,4HWH2@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
REGS1_k127_8457125_2	1347086.CCBA010000039_gene4931	5.65e-78	274.0	COG2110@1|root,COG2110@2|Bacteria,1UY8V@1239|Firmicutes,4HD2D@91061|Bacilli,1ZIP1@1386|Bacillus	91061|Bacilli	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
REGS1_k127_8457125_5	2340.JV46_09710	2.25e-05	56.0	COG2981@1|root,COG2981@2|Bacteria,1MVFT@1224|Proteobacteria,1RMQT@1236|Gammaproteobacteria,1J5RJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	U	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway	cysZ	GO:0000096,GO:0000097,GO:0000103,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0008150,GO:0008152,GO:0008271,GO:0008272,GO:0008324,GO:0008509,GO:0008512,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009675,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015103,GO:0015116,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015296,GO:0015318,GO:0015672,GO:0015698,GO:0016020,GO:0016021,GO:0016053,GO:0019344,GO:0019752,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0046394,GO:0051179,GO:0051234,GO:0055085,GO:0071704,GO:0071944,GO:0072348,GO:0098655,GO:0098656,GO:0098660,GO:0098661,GO:0098662,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901682,GO:1902358,GO:1902600	-	ko:K06203	-	-	-	-	ko00000	-	-	iJR904.b2413,iYL1228.KPN_02760	EI24
REGS1_k127_8457125_0	290397.Adeh_3796	0.0	1324.0	COG0793@1|root,COG1361@1|root,COG0793@2|Bacteria,COG1361@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WTUX@28221|Deltaproteobacteria,2YTTM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
REGS1_k127_8486503_2	404589.Anae109_2350	7.505e-113	372.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,2YZWP@29|Myxococcales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
REGS1_k127_8486503_1	290397.Adeh_1494	7.037e-130	436.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2YVDX@29|Myxococcales	28221|Deltaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
REGS1_k127_8486503_0	290397.Adeh_1495	1.678e-314	975.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2YUHW@29|Myxococcales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
REGS1_k127_8489152_7	215803.DB30_7046	1.343e-19	90.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,2YUNP@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
REGS1_k127_8489152_5	391625.PPSIR1_01637	2.487e-41	164.0	COG4894@1|root,COG4894@2|Bacteria,1RFQF@1224|Proteobacteria,431MS@68525|delta/epsilon subdivisions,2WWKG@28221|Deltaproteobacteria,2YXVC@29|Myxococcales	28221|Deltaproteobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	Scramblase
REGS1_k127_8489152_4	404589.Anae109_2817	4.113e-45	178.0	2AN6E@1|root,31D4B@2|Bacteria,1QA73@1224|Proteobacteria,434VH@68525|delta/epsilon subdivisions,2X91G@28221|Deltaproteobacteria,2Z1FK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8489152_6	1116375.VEJY3_05545	4.418e-24	115.0	2A1U9@1|root,30Q38@2|Bacteria,1QKWJ@1224|Proteobacteria,1TJ27@1236|Gammaproteobacteria,1Y0CD@135623|Vibrionales	135623|Vibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8489152_0	290397.Adeh_1870	2.134e-232	740.0	COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUE5@29|Myxococcales	28221|Deltaproteobacteria	D	HAD superfamily (subfamily IG) hydrolase 5'-Nucleotidase	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid
REGS1_k127_8489152_1	290397.Adeh_1867	2.297e-207	652.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42Z0A@68525|delta/epsilon subdivisions,2WUAC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_8489152_2	290397.Adeh_1866	4.575e-175	558.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WR3G@28221|Deltaproteobacteria,2YXS5@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_8489152_3	290397.Adeh_1865	1.555e-86	304.0	COG0564@1|root,COG0564@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	-	-	5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29	ko:K06177,ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2,S4
REGS1_k127_8496035_5	251221.35212591	2.783e-08	66.0	COG3744@1|root,COG3744@2|Bacteria,1G89C@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_8496035_3	378806.STAUR_2126	9.824e-136	442.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42U7Q@68525|delta/epsilon subdivisions,2X8TG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_8496035_4	1429916.X566_05280	1.752e-37	145.0	COG5507@1|root,COG5507@2|Bacteria,1RHC1@1224|Proteobacteria,2UC7A@28211|Alphaproteobacteria,3JYUE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1428)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1428
REGS1_k127_8496035_0	404589.Anae109_0737	0.0	1268.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2YUJ4@29|Myxococcales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
REGS1_k127_8496035_1	378806.STAUR_6321	4.954e-209	677.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2YTXT@29|Myxococcales	28221|Deltaproteobacteria	J	Ribonuclease E/G family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
REGS1_k127_8496035_2	404589.Anae109_0739	6.542e-136	450.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,2Z0P6@29|Myxococcales	28221|Deltaproteobacteria	K	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
REGS1_k127_8496248_0	861299.J421_5987	2.165e-140	454.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria	2|Bacteria	L	DNA ligase (ATP) activity	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
REGS1_k127_8496248_1	861299.J421_5988	4.654e-97	325.0	COG1273@1|root,COG1273@2|Bacteria	2|Bacteria	M	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
REGS1_k127_8496248_2	290397.Adeh_0883	2.299e-36	143.0	COG0457@1|root,COG0457@2|Bacteria,1N4HS@1224|Proteobacteria,43753@68525|delta/epsilon subdivisions,2X219@28221|Deltaproteobacteria,2Z10F@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11
REGS1_k127_8498584_8	264462.Bd3071	2.494e-16	93.0	COG1352@1|root,COG1352@2|Bacteria,1QY2J@1224|Proteobacteria,43AK1@68525|delta/epsilon subdivisions,2MTJG@213481|Bdellovibrionales,2X60B@28221|Deltaproteobacteria	213481|Bdellovibrionales	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8498584_5	290397.Adeh_0428	8.049e-53	194.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,PAS_3,PAS_4,PAS_9,SpoIIE
REGS1_k127_8498584_3	290397.Adeh_0427	5.794e-114	382.0	COG1538@1|root,COG1538@2|Bacteria,1R8XP@1224|Proteobacteria,42QM9@68525|delta/epsilon subdivisions,2WKY8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	ko:K12543	-	M00330	-	-	ko00000,ko00002,ko02000,ko02044	1.B.17,3.A.1.109.4	-	-	OEP
REGS1_k127_8498584_0	404589.Anae109_4144	2.903e-220	730.0	COG0457@1|root,COG0457@2|Bacteria,1RJUD@1224|Proteobacteria,42P27@68525|delta/epsilon subdivisions,2WK9Y@28221|Deltaproteobacteria,2Z2Z5@29|Myxococcales	28221|Deltaproteobacteria	PT	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_8,TonB_dep_Rec,zinc_ribbon_4
REGS1_k127_8498584_1	404589.Anae109_4145	1.835e-129	419.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
REGS1_k127_8498584_2	290397.Adeh_0423	3.102e-127	429.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YU8R@29|Myxococcales	28221|Deltaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_8498584_6	1009370.ALO_12199	5.328e-32	132.0	2BVWV@1|root,30VPQ@2|Bacteria,1W4RQ@1239|Firmicutes	1239|Firmicutes	S	Uncharacterized protein conserved in bacteria (DUF2247)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2247
REGS1_k127_8498584_9	1009370.ALO_12194	7.407e-15	76.0	299ZK@1|root,2ZX17@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8498584_4	404589.Anae109_4148	4.568e-59	210.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,42Q9R@68525|delta/epsilon subdivisions,2WKU4@28221|Deltaproteobacteria,2Z2YS@29|Myxococcales	28221|Deltaproteobacteria	O	Hsp33 protein	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
REGS1_k127_8501939_0	290397.Adeh_2560	1.105e-189	601.0	COG1387@1|root,COG1796@1|root,COG1387@2|Bacteria,COG1796@2|Bacteria,1MYXV@1224|Proteobacteria,42MQX@68525|delta/epsilon subdivisions,2WKUP@28221|Deltaproteobacteria,2YXCT@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase beta thumb	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_palm,DNA_pol_B_thumb,HHH_5,HHH_8,PHP
REGS1_k127_8501939_4	290397.Adeh_2558	7.548e-74	271.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42R2A@68525|delta/epsilon subdivisions,2WMUK@28221|Deltaproteobacteria,2YVHG@29|Myxococcales	28221|Deltaproteobacteria	H	May be involved in the biosynthesis of molybdopterin	moaB	-	2.7.7.75	ko:K03638	ko00790,ko01100,map00790,map01100	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
REGS1_k127_8501939_2	290397.Adeh_2557	2.693e-118	395.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,2YW8E@29|Myxococcales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
REGS1_k127_8501939_1	290397.Adeh_2556	3.903e-176	567.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,42QEZ@68525|delta/epsilon subdivisions,2WKYB@28221|Deltaproteobacteria,2YZA0@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_8501939_3	404589.Anae109_1308	1.911e-103	338.0	COG1624@1|root,COG1624@2|Bacteria,1N12B@1224|Proteobacteria,42UVR@68525|delta/epsilon subdivisions,2WQ2R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Diadenylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
REGS1_k127_8507861_3	290397.Adeh_0421	5.712e-09	57.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,42Q9R@68525|delta/epsilon subdivisions,2WKU4@28221|Deltaproteobacteria,2Z2YS@29|Myxococcales	28221|Deltaproteobacteria	O	Hsp33 protein	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
REGS1_k127_8507861_2	404589.Anae109_4149	1.641e-70	247.0	COG2236@1|root,COG2236@2|Bacteria,1NHGS@1224|Proteobacteria	1224|Proteobacteria	F	Phosphoribosyl transferase domain	-	-	-	ko:K07101	-	-	-	-	ko00000	-	-	-	Pribosyltran
REGS1_k127_8507861_0	404589.Anae109_4150	3.097e-285	889.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,2YU0Y@29|Myxococcales	28221|Deltaproteobacteria	J	Selenocysteine-specific translation elongation factor	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
REGS1_k127_8507861_1	290397.Adeh_0418	3.456e-78	289.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1QYFP@1224|Proteobacteria,43CBV@68525|delta/epsilon subdivisions,2X7MN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3,HATPase_c,HisKA
REGS1_k127_8528590_1	404589.Anae109_3030	7.184e-165	521.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,42NE5@68525|delta/epsilon subdivisions,2WJ14@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
REGS1_k127_8528590_0	338966.Ppro_3468	4.809e-211	670.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2WJZI@28221|Deltaproteobacteria,43TBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
REGS1_k127_8537437_9	404589.Anae109_0252	5.194e-48	176.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,42MX0@68525|delta/epsilon subdivisions,2WM16@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM Multi antimicrobial extrusion protein MatE	norM-2	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
REGS1_k127_8537437_7	85643.Tmz1t_2040	3.517e-87	299.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,2VKZK@28216|Betaproteobacteria,2KUFY@206389|Rhodocyclales	206389|Rhodocyclales	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
REGS1_k127_8537437_1	1297742.A176_05581	1.876e-295	930.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,42M2T@68525|delta/epsilon subdivisions,2WJ2W@28221|Deltaproteobacteria,2YUIP@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_8537437_10	404589.Anae109_0836	2.98e-41	155.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
REGS1_k127_8537437_6	290397.Adeh_0792	1.601e-104	343.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2YUHQ@29|Myxococcales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
REGS1_k127_8537437_4	290397.Adeh_0794	8.733e-122	410.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,43AKN@68525|delta/epsilon subdivisions,2X60M@28221|Deltaproteobacteria,2Z1JH@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
REGS1_k127_8537437_8	404589.Anae109_2839	2.816e-73	251.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,2YW7D@29|Myxococcales	28221|Deltaproteobacteria	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
REGS1_k127_8537437_2	290397.Adeh_0812	5.018e-177	566.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_8537437_5	290397.Adeh_0813	1.183e-119	390.0	COG0755@1|root,COG0755@2|Bacteria,1RG6M@1224|Proteobacteria,43BH8@68525|delta/epsilon subdivisions,2X6VM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_8537437_3	290397.Adeh_0814	5.987e-169	551.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	-	-	-	-	-	-	-	-	-	ResB
REGS1_k127_8537437_0	290397.Adeh_0817	0.0	1129.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
REGS1_k127_8538173_1	1340493.JNIF01000004_gene1119	1.846e-34	143.0	COG0451@1|root,COG0451@2|Bacteria,3Y95U@57723|Acidobacteria	57723|Acidobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_8541277_6	290397.Adeh_3114	8.579e-77	280.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
REGS1_k127_8541277_2	404589.Anae109_0894	6.142e-132	441.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990,ko:K01992,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC2_membrane_3,ABC_tran
REGS1_k127_8541277_5	404589.Anae109_0893	9.96e-103	348.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria,2Z2W7@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ybhF-N	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
REGS1_k127_8541277_4	290397.Adeh_3111	2.182e-107	358.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_8541277_1	404589.Anae109_0891	3.305e-134	440.0	COG1538@1|root,COG1538@2|Bacteria,1Q6D1@1224|Proteobacteria,432WU@68525|delta/epsilon subdivisions,2WXU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_8541277_3	290397.Adeh_0834	1.439e-128	429.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA
REGS1_k127_8541277_0	404589.Anae109_0889	2.955e-159	531.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_8566481_2	290397.Adeh_3707	3.886e-121	392.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1	ko:K01739,ko:K01758	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
REGS1_k127_8566481_1	404589.Anae109_3839	1.587e-156	501.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WKF9@28221|Deltaproteobacteria,2YXTE@29|Myxococcales	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
REGS1_k127_8566481_0	290397.Adeh_3722	7.706e-177	561.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
REGS1_k127_8566481_3	404589.Anae109_3852	7.116e-97	330.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
REGS1_k127_8575901_2	861299.J421_1872	7.147e-52	190.0	COG2303@1|root,COG2303@2|Bacteria	2|Bacteria	E	choline dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
REGS1_k127_8575901_0	234267.Acid_3143	8.454e-176	577.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	glgX	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
REGS1_k127_8575901_4	330214.NIDE1131	1.453e-20	94.0	COG1452@1|root,COG1452@2|Bacteria	2|Bacteria	M	lipopolysaccharide transport	-	-	-	ko:K22110	-	-	-	-	ko00000,ko02000	1.B.35.1,1.B.35.2	-	-	Glyco_hydro_63
REGS1_k127_8575901_3	497964.CfE428DRAFT_5116	8.901e-22	98.0	2942H@1|root,2ZRH9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8575901_1	1121920.AUAU01000005_gene1045	3.906e-66	229.0	COG0329@1|root,COG0329@2|Bacteria,3Y8R8@57723|Acidobacteria	57723|Acidobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
REGS1_k127_8576872_3	338966.Ppro_3493	1.532e-33	137.0	COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,42SWB@68525|delta/epsilon subdivisions,2WPMC@28221|Deltaproteobacteria,43U5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_8576872_2	404589.Anae109_0351	2.666e-51	184.0	COG1765@1|root,COG1765@2|Bacteria,1QF2H@1224|Proteobacteria,42VZN@68525|delta/epsilon subdivisions,2WSEZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
REGS1_k127_8576872_4	1173022.Cri9333_1638	8.01e-23	101.0	COG2361@1|root,COG2361@2|Bacteria,1G82N@1117|Cyanobacteria,1HDBR@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
REGS1_k127_8576872_5	379066.GAU_0073	6.69e-15	78.0	COG1669@1|root,COG1669@2|Bacteria,1ZUYI@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
REGS1_k127_8576872_1	404589.Anae109_2900	2.028e-70	252.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH,HNH_4
REGS1_k127_8576872_0	522306.CAP2UW1_4231	5.027e-82	280.0	COG3440@1|root,COG3440@2|Bacteria,1N4JP@1224|Proteobacteria,2VVU0@28216|Betaproteobacteria	28216|Betaproteobacteria	V	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
REGS1_k127_8585305_2	404589.Anae109_4355	1.312e-96	331.0	COG3356@1|root,COG3356@2|Bacteria,1Q66U@1224|Proteobacteria,4358C@68525|delta/epsilon subdivisions,2WZJF@28221|Deltaproteobacteria,2Z29I@29|Myxococcales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
REGS1_k127_8585305_0	290397.Adeh_4206	3.758e-253	791.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,2YTTF@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
REGS1_k127_8585305_5	290397.Adeh_4204	8.111e-08	53.0	COG1723@1|root,COG1723@2|Bacteria,1R8R9@1224|Proteobacteria,42W7V@68525|delta/epsilon subdivisions,2WS5C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8635824_5	290397.Adeh_1136	1.995e-06	50.0	COG3437@1|root,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42MD7@68525|delta/epsilon subdivisions,2WJH1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,Response_reg
REGS1_k127_8635824_1	404589.Anae109_1183	3.81e-136	448.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
REGS1_k127_8635824_4	404589.Anae109_1182	4.665e-50	180.0	2EH48@1|root,33AW7@2|Bacteria,1NIYU@1224|Proteobacteria,42XKK@68525|delta/epsilon subdivisions,2WSKU@28221|Deltaproteobacteria,2Z1HY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8635824_2	404589.Anae109_1171	3.989e-114	377.0	COG0697@1|root,COG0697@2|Bacteria,1MX1Y@1224|Proteobacteria,42NTW@68525|delta/epsilon subdivisions,2WMEN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_8635824_0	404589.Anae109_1170	0.0	1622.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YUJ6@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
REGS1_k127_8635824_3	404589.Anae109_2321	2.091e-82	312.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42RAB@68525|delta/epsilon subdivisions,2X5MA@28221|Deltaproteobacteria,2Z369@29|Myxococcales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
REGS1_k127_8653297_2	1144275.COCOR_05146	1.128e-16	91.0	2AIZJ@1|root,319HM@2|Bacteria,1Q2SU@1224|Proteobacteria,438EK@68525|delta/epsilon subdivisions,2X3PJ@28221|Deltaproteobacteria,2YWS6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
REGS1_k127_8653297_1	1242864.D187_002017	9.567e-68	244.0	COG1028@1|root,COG1028@2|Bacteria,1MW4W@1224|Proteobacteria,43DGY@68525|delta/epsilon subdivisions,2X8NT@28221|Deltaproteobacteria,2YUWT@29|Myxococcales	28221|Deltaproteobacteria	IQ	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_8653297_4	391625.PPSIR1_25151	1.109e-08	63.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,DUF2330,STN,TonB_2,TonB_C
REGS1_k127_8653297_0	404589.Anae109_1731	4.695e-120	402.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7V@28221|Deltaproteobacteria,2Z1U0@29|Myxococcales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
REGS1_k127_8668146_8	404589.Anae109_0934	4.093e-43	161.0	COG1585@1|root,COG1585@2|Bacteria,1PJH9@1224|Proteobacteria,42WNG@68525|delta/epsilon subdivisions,2WRM8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	OU	NfeD-like C-terminal, partner-binding	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
REGS1_k127_8668146_2	290397.Adeh_0881	1.756e-149	487.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WKYT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
REGS1_k127_8668146_3	290397.Adeh_0887	6.657e-135	445.0	COG0668@1|root,COG0668@2|Bacteria,1MXD2@1224|Proteobacteria,42M92@68525|delta/epsilon subdivisions,2WJ7J@28221|Deltaproteobacteria,2YVBA@29|Myxococcales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	-	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
REGS1_k127_8668146_0	290397.Adeh_0888	2.924e-257	813.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria	2|Bacteria	L	chaperone-mediated protein folding	bcr4	-	-	ko:K21007	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	TPR_15,TPR_16,TPR_19,TPR_2
REGS1_k127_8668146_10	404589.Anae109_0948	1.704e-20	96.0	28S5K@1|root,2ZEH5@2|Bacteria,1NI42@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (FYDLN_acid)	-	-	-	-	-	-	-	-	-	-	-	-	FYDLN_acid
REGS1_k127_8668146_13	378806.STAUR_6384	1.753e-06	60.0	COG4260@1|root,COG4260@2|Bacteria,1Q3KA@1224|Proteobacteria,439DA@68525|delta/epsilon subdivisions,2X4N2@28221|Deltaproteobacteria,2YZA2@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,zinc_ribbon_4
REGS1_k127_8668146_6	290397.Adeh_0904	2.636e-58	224.0	COG0274@1|root,COG0274@2|Bacteria,1N8AG@1224|Proteobacteria,42S16@68525|delta/epsilon subdivisions,2WNEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
REGS1_k127_8668146_5	290397.Adeh_1182	7.806e-63	232.0	COG1051@1|root,COG1051@2|Bacteria,1N5QT@1224|Proteobacteria,433SX@68525|delta/epsilon subdivisions,2WXYA@28221|Deltaproteobacteria,2YVMP@29|Myxococcales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_8668146_9	290397.Adeh_0865	3.944e-41	156.0	COG3695@1|root,COG3695@2|Bacteria,1PZ1K@1224|Proteobacteria,42WV5@68525|delta/epsilon subdivisions,2WT08@28221|Deltaproteobacteria,2YVVE@29|Myxococcales	28221|Deltaproteobacteria	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
REGS1_k127_8668146_12	305700.B447_07709	7.246e-08	63.0	COG0348@1|root,COG3901@1|root,COG0348@2|Bacteria,COG3901@2|Bacteria,1MY5M@1224|Proteobacteria,2VH7V@28216|Betaproteobacteria,2KXJC@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_10,Fer4_5
REGS1_k127_8668146_1	290397.Adeh_0905	9.479e-199	625.0	COG1015@1|root,COG1015@2|Bacteria,1MVN8@1224|Proteobacteria,42NKQ@68525|delta/epsilon subdivisions,2WJVF@28221|Deltaproteobacteria,2YX5T@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
REGS1_k127_8668146_4	404589.Anae109_0587	9.243e-113	373.0	COG3439@1|root,COG3439@2|Bacteria,1MXYT@1224|Proteobacteria,42VE6@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8677866_8	290397.Adeh_2379	3.084e-41	156.0	COG5662@1|root,COG5662@2|Bacteria,1PC36@1224|Proteobacteria,4387X@68525|delta/epsilon subdivisions,2X3HP@28221|Deltaproteobacteria,2YW5D@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
REGS1_k127_8677866_6	290397.Adeh_2378	1.258e-71	263.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_8677866_0	404589.Anae109_1490	7.391e-213	669.0	COG2896@1|root,COG2896@2|Bacteria,1MXMH@1224|Proteobacteria,42NTM@68525|delta/epsilon subdivisions,2WKIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_8677866_1	290397.Adeh_2376	2.061e-199	648.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,2YUWI@29|Myxococcales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
REGS1_k127_8677866_10	1242864.D187_007171	4.062e-23	107.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
REGS1_k127_8677866_9	404589.Anae109_4243	2.114e-40	167.0	arCOG10456@1|root,2ZA6T@2|Bacteria,1R4VS@1224|Proteobacteria,42XB3@68525|delta/epsilon subdivisions,2WSSI@28221|Deltaproteobacteria,2Z2IJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8677866_7	404589.Anae109_1494	1.715e-57	214.0	COG1266@1|root,COG1266@2|Bacteria,1PPHW@1224|Proteobacteria,43E4M@68525|delta/epsilon subdivisions,2WZQ1@28221|Deltaproteobacteria,2Z2HR@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
REGS1_k127_8677866_2	290397.Adeh_2372	9.75e-195	619.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,2YUKH@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
REGS1_k127_8677866_4	290397.Adeh_2371	1.301e-114	385.0	28Q1P@1|root,2ZCJY@2|Bacteria,1RCE9@1224|Proteobacteria,42R28@68525|delta/epsilon subdivisions,2WN78@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
REGS1_k127_8677866_5	404589.Anae109_1500	4.594e-105	350.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,2YUZZ@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_8677866_3	404589.Anae109_1501	1.216e-166	537.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,42MWM@68525|delta/epsilon subdivisions,2WK3H@28221|Deltaproteobacteria,2YZNI@29|Myxococcales	28221|Deltaproteobacteria	O	NfeD-like C-terminal, partner-binding	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD,SDH_sah
REGS1_k127_8677866_11	404589.Anae109_1502	7.842e-13	69.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,2YZ16@29|Myxococcales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_8680491_2	404589.Anae109_3440	1.12e-79	268.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YUNQ@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	rep	-	3.6.4.12	ko:K03656,ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_8680491_5	1463853.JOHW01000031_gene2912	4.097e-15	80.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
REGS1_k127_8680491_0	1123487.KB892835_gene3700	7.582e-138	445.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,2KUU0@206389|Rhodocyclales	206389|Rhodocyclales	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_8680491_3	404589.Anae109_3437	1.286e-70	242.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2YVJG@29|Myxococcales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
REGS1_k127_8680491_4	290397.Adeh_3371	3.422e-66	227.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2YV9P@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
REGS1_k127_8680491_1	290397.Adeh_3368	7.417e-104	339.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,2YWA0@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_8696669_0	404589.Anae109_3844	1.771e-199	634.0	COG0477@1|root,COG0477@2|Bacteria,1MWUR@1224|Proteobacteria,43BPW@68525|delta/epsilon subdivisions,2X5ED@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_8704169_9	404589.Anae109_3692	6.734e-61	211.0	COG1664@1|root,COG1664@2|Bacteria,1RHS7@1224|Proteobacteria	1224|Proteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_8704169_8	290397.Adeh_3570	2.111e-69	239.0	COG1664@1|root,COG1664@2|Bacteria,1QAFI@1224|Proteobacteria,4351U@68525|delta/epsilon subdivisions,2WZCU@28221|Deltaproteobacteria,2Z1UZ@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_8704169_5	290397.Adeh_3569	2.369e-92	309.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
REGS1_k127_8704169_4	290397.Adeh_3568	4.405e-94	313.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WPAX@28221|Deltaproteobacteria,2Z2Z0@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
REGS1_k127_8704169_1	933262.AXAM01000018_gene1005	4.585e-196	625.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2MIMB@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_8704169_7	290397.Adeh_3565	2.94e-75	258.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,2YV7H@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
REGS1_k127_8704169_3	404589.Anae109_3685	3.063e-127	423.0	COG0457@1|root,COG2013@1|root,COG0457@2|Bacteria,COG2013@2|Bacteria,1NHMN@1224|Proteobacteria,43CDQ@68525|delta/epsilon subdivisions,2X7PM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
REGS1_k127_8704169_6	290397.Adeh_3563	6.258e-91	322.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,2YVBE@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_8704169_2	404589.Anae109_3683	1.706e-152	498.0	COG0859@1|root,COG0859@2|Bacteria,1N112@1224|Proteobacteria,42MUI@68525|delta/epsilon subdivisions,2WU9M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
REGS1_k127_8704169_0	744872.Spica_0555	5.63e-295	945.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2J5ZA@203691|Spirochaetes	203691|Spirochaetes	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
REGS1_k127_8722986_0	1254432.SCE1572_20505	4.611e-122	404.0	COG0477@1|root,COG2814@2|Bacteria,1PATR@1224|Proteobacteria,437WJ@68525|delta/epsilon subdivisions,2WYPZ@28221|Deltaproteobacteria,2YUGK@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	mmrA	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
REGS1_k127_8722986_3	160860.XP_007357210.1	6.393e-32	142.0	KOG1225@1|root,KOG1225@2759|Eukaryota	2759|Eukaryota	L	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	-	-	-	ko:K01691,ko:K13539	ko04310,map04310	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03036	-	-	-	Peptidase_M8,WIF
REGS1_k127_8722986_5	324602.Caur_0299	0.0001701	52.0	COG5295@1|root,COG5295@2|Bacteria,2GB82@200795|Chloroflexi,377IZ@32061|Chloroflexia	32061|Chloroflexia	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
REGS1_k127_8722986_1	404589.Anae109_2493	2.583e-63	218.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2YU4B@29|Myxococcales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
REGS1_k127_8734504_0	290397.Adeh_2602	1.127e-237	743.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,43BJP@68525|delta/epsilon subdivisions,2WJWZ@28221|Deltaproteobacteria,2YUKJ@29|Myxococcales	28221|Deltaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2,4.3.1.1	ko:K01679,ko:K01744	ko00020,ko00250,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00250,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R00490,R01082	RC00316,RC00443,RC02799	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
REGS1_k127_8734504_7	573370.DMR_26740	3.305e-91	326.0	COG1305@1|root,COG1305@2|Bacteria,1MY5V@1224|Proteobacteria,42M7B@68525|delta/epsilon subdivisions,2WJUM@28221|Deltaproteobacteria,2MAY3@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
REGS1_k127_8734504_6	706587.Desti_5047	4.987e-115	399.0	COG0745@1|root,COG0784@1|root,COG5002@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
REGS1_k127_8734504_1	1121920.AUAU01000005_gene1032	6.22e-156	500.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,3Y4JU@57723|Acidobacteria	57723|Acidobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
REGS1_k127_8734504_11	29581.BW37_03261	9.464e-38	155.0	COG3693@1|root,COG3693@2|Bacteria,1P7A6@1224|Proteobacteria,2W464@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Domain of unknown function (DUF4424)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4424
REGS1_k127_8734504_12	331678.Cphamn1_0871	2.31e-35	136.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
REGS1_k127_8734504_14	402777.KB235903_gene647	4.797e-24	105.0	COG2361@1|root,COG2361@2|Bacteria,1G7XA@1117|Cyanobacteria,1HCYZ@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
REGS1_k127_8734504_8	1123020.AUIE01000007_gene3314	6.518e-87	295.0	COG4757@1|root,COG4757@2|Bacteria,1Q1V6@1224|Proteobacteria,1S3FE@1236|Gammaproteobacteria,1YKHU@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
REGS1_k127_8734504_2	290397.Adeh_0190	3.221e-148	475.0	COG1215@1|root,COG1215@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,2Z2XX@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_8734504_9	404589.Anae109_0209	5.36e-58	223.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2WP6E@28221|Deltaproteobacteria,2YVRN@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
REGS1_k127_8734504_4	404589.Anae109_0208	1.976e-135	447.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WJKR@28221|Deltaproteobacteria,2YV4V@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
REGS1_k127_8734504_13	861299.J421_0927	3.403e-32	146.0	COG0612@1|root,COG0612@2|Bacteria,1ZT6X@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Insulinase (Peptidase family M16)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_8734504_10	483219.LILAB_08765	2.015e-47	188.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,2YU8N@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_8734504_15	1449346.JQMO01000002_gene1090	2.349e-18	93.0	COG0703@1|root,COG0703@2|Bacteria,2GRFW@201174|Actinobacteria,2M2PD@2063|Kitasatospora	201174|Actinobacteria	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019438,GO:0019632,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
REGS1_k127_8734504_5	404589.Anae109_0206	3.027e-117	381.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,2YVCP@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
REGS1_k127_8739596_4	404589.Anae109_1892	1.027e-172	546.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MRV@68525|delta/epsilon subdivisions,2WK9C@28221|Deltaproteobacteria,2YZ1X@29|Myxococcales	28221|Deltaproteobacteria	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFO_beta_C,TPP_enzyme_C
REGS1_k127_8739596_1	404589.Anae109_1891	0.0	1014.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,1NBSJ@1224|Proteobacteria,42MXV@68525|delta/epsilon subdivisions,2WIIT@28221|Deltaproteobacteria,2YY6V@29|Myxococcales	28221|Deltaproteobacteria	C	Pyruvate flavodoxin ferredoxin	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
REGS1_k127_8739596_2	404589.Anae109_1890	9.914e-238	742.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2YU4J@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
REGS1_k127_8739596_5	404589.Anae109_1888	2.093e-79	272.0	COG0302@1|root,COG0302@2|Bacteria,1MY3N@1224|Proteobacteria,42N1U@68525|delta/epsilon subdivisions,2X2RV@28221|Deltaproteobacteria,2YW4J@29|Myxococcales	28221|Deltaproteobacteria	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
REGS1_k127_8739596_6	404589.Anae109_1886	9.144e-48	173.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,42TK0@68525|delta/epsilon subdivisions,2WQ5D@28221|Deltaproteobacteria,2YVCZ@29|Myxococcales	28221|Deltaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_8739596_0	404589.Anae109_1884	0.0	1175.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
REGS1_k127_8739596_3	404589.Anae109_1883	1.338e-204	639.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2YWE0@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
REGS1_k127_8739596_8	404589.Anae109_1882	1.409e-11	64.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,2YVYH@29|Myxococcales	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
REGS1_k127_8740509_8	404589.Anae109_1641	1.848e-105	346.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,42PIX@68525|delta/epsilon subdivisions,2WJRF@28221|Deltaproteobacteria,2Z360@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
REGS1_k127_8740509_9	404589.Anae109_1642	5.49e-86	311.0	COG0175@1|root,COG0529@1|root,COG0175@2|Bacteria,COG0529@2|Bacteria,1MX0D@1224|Proteobacteria,42ZXZ@68525|delta/epsilon subdivisions,2WVI7@28221|Deltaproteobacteria,2YV2C@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of activated sulfate	cysC	-	1.8.4.10,1.8.4.8,2.7.1.25	ko:K00390,ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	M00176	R00509,R02021,R04928	RC00002,RC00007,RC00078,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase
REGS1_k127_8740509_2	404589.Anae109_1643	9.73e-185	606.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,42N3C@68525|delta/epsilon subdivisions,2WKCB@28221|Deltaproteobacteria,2YUDM@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_8740509_4	404589.Anae109_1644	2.532e-167	530.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,42NYE@68525|delta/epsilon subdivisions,2WK6Q@28221|Deltaproteobacteria,2YTSR@29|Myxococcales	28221|Deltaproteobacteria	H	Phosphoadenosine phosphosulfate reductase family	-	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
REGS1_k127_8740509_11	404589.Anae109_3610	4.03e-65	240.0	COG1310@1|root,COG1310@2|Bacteria,1PBUE@1224|Proteobacteria,435H8@68525|delta/epsilon subdivisions,2WZUV@28221|Deltaproteobacteria,2Z2SW@29|Myxococcales	28221|Deltaproteobacteria	S	Prokaryotic homologs of the JAB domain	-	-	-	-	-	-	-	-	-	-	-	-	Prok-JAB
REGS1_k127_8740509_6	404589.Anae109_3609	3.565e-150	486.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2YU2W@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
REGS1_k127_8740509_15	330084.JNYZ01000056_gene3896	4.14e-12	76.0	2AN8T@1|root,31D6V@2|Bacteria,2IHRU@201174|Actinobacteria,4E3N2@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
REGS1_k127_8740509_3	404589.Anae109_3607	3.568e-178	568.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
REGS1_k127_8740509_14	290397.Adeh_3494	2.189e-33	133.0	COG1977@1|root,COG1977@2|Bacteria,1N15U@1224|Proteobacteria,42XSH@68525|delta/epsilon subdivisions,2WTDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_8740509_1	404589.Anae109_3605	8.456e-207	650.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2YTVW@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	-	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_8740509_0	404589.Anae109_3604	4.63e-234	738.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,2YU8G@29|Myxococcales	28221|Deltaproteobacteria	C	Sulfite reductase	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
REGS1_k127_8740509_10	1167006.UWK_02103	4.206e-84	287.0	COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,42TZD@68525|delta/epsilon subdivisions,2WQIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphonate ABC transporter, periplasmic	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_8740509_5	290397.Adeh_3162	3.624e-153	516.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,dCache_1,dCache_2,dCache_3,sCache_2
REGS1_k127_8740509_7	290397.Adeh_3493	3.749e-110	369.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria,2YUA5@29|Myxococcales	28221|Deltaproteobacteria	HP	domain protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
REGS1_k127_8740509_12	404589.Anae109_0751	3.07e-60	210.0	COG3930@1|root,COG3930@2|Bacteria,1PYFH@1224|Proteobacteria,42ZAK@68525|delta/epsilon subdivisions,2WUH8@28221|Deltaproteobacteria,2YUXI@29|Myxococcales	28221|Deltaproteobacteria	S	DUF1704	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704,FGase
REGS1_k127_8750047_5	290397.Adeh_3740	3.62e-113	368.0	COG0515@1|root,COG0515@2|Bacteria	290397.Adeh_3740|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8750047_7	404589.Anae109_3856	3.689e-78	279.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,42SUR@68525|delta/epsilon subdivisions,2WPNH@28221|Deltaproteobacteria,2Z2JJ@29|Myxococcales	28221|Deltaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
REGS1_k127_8750047_8	290397.Adeh_3732	2.241e-70	249.0	COG2267@1|root,COG2267@2|Bacteria,1MUG8@1224|Proteobacteria,43CCW@68525|delta/epsilon subdivisions,2X7NT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Alpha/beta hydrolase family	-	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
REGS1_k127_8750047_20	1286093.C266_14592	1.477e-06	56.0	COG0586@1|root,COG0607@1|root,COG0586@2|Bacteria,COG0607@2|Bacteria,1R6F1@1224|Proteobacteria,2VMW2@28216|Betaproteobacteria,1K3HB@119060|Burkholderiaceae	28216|Betaproteobacteria	P	SMART Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,SNARE_assoc
REGS1_k127_8750047_4	246197.MXAN_2386	5.189e-124	422.0	COG0745@1|root,COG0784@1|root,COG4191@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2Z2WF@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_8750047_16	1266925.JHVX01000002_gene911	1.931e-19	104.0	2BMS7@1|root,32GBK@2|Bacteria,1PW7Y@1224|Proteobacteria,2WBSX@28216|Betaproteobacteria,373QZ@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8750047_15	1242864.D187_002134	1.771e-28	130.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	DUF3365,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_8750047_1	215803.DB30_5765	8.115e-147	482.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,4301R@68525|delta/epsilon subdivisions,2WVCA@28221|Deltaproteobacteria,2YYZK@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_8750047_0	290397.Adeh_0302	7.967e-185	635.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YY7A@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_8750047_11	246197.MXAN_3623	3.578e-39	155.0	COG0625@1|root,COG0625@2|Bacteria,1PD8F@1224|Proteobacteria,435EY@68525|delta/epsilon subdivisions,2WZSI@28221|Deltaproteobacteria,2Z2NR@29|Myxococcales	28221|Deltaproteobacteria	H	glutathione S-transferase	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_3,GST_N
REGS1_k127_8750047_17	404589.Anae109_4309	1.267e-15	79.0	COG0425@1|root,COG0425@2|Bacteria,1P4MT@1224|Proteobacteria	1224|Proteobacteria	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
REGS1_k127_8750047_14	404589.Anae109_2778	4.402e-31	124.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,4399V@68525|delta/epsilon subdivisions,2X4HB@28221|Deltaproteobacteria,2YZ0N@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_8750047_18	404589.Anae109_2778	8.132e-15	77.0	COG1225@1|root,COG1225@2|Bacteria,1RER0@1224|Proteobacteria,4399V@68525|delta/epsilon subdivisions,2X4HB@28221|Deltaproteobacteria,2YZ0N@29|Myxococcales	28221|Deltaproteobacteria	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_8750047_9	290397.Adeh_3029	2.53e-52	191.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,2YW8F@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
REGS1_k127_8750047_2	391625.PPSIR1_41409	2.088e-143	464.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42N1P@68525|delta/epsilon subdivisions,2WM2V@28221|Deltaproteobacteria,2YU4D@29|Myxococcales	28221|Deltaproteobacteria	E	Aminotransferase	-	-	2.6.1.17,2.6.1.88	ko:K14267,ko:K14287	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475,R08618	RC00006,RC00025	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_8750047_3	290397.Adeh_3726	3.057e-142	509.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,42MAN@68525|delta/epsilon subdivisions,2WJBB@28221|Deltaproteobacteria,2YUT5@29|Myxococcales	28221|Deltaproteobacteria	J	tRNA synthetases class II (D, K and N)	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
REGS1_k127_8750047_6	290397.Adeh_3897	6.22e-102	351.0	COG0840@1|root,COG5000@1|root,COG0840@2|Bacteria,COG5000@2|Bacteria,1MU9B@1224|Proteobacteria,42KZR@68525|delta/epsilon subdivisions,2WJ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
REGS1_k127_8750047_13	404589.Anae109_3497	8.029e-37	146.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2WQ2M@28221|Deltaproteobacteria,2Z1K8@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
REGS1_k127_8750047_10	1254432.SCE1572_24340	1.802e-45	186.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_8750047_19	1184609.KILIM_021_00400	2.315e-11	75.0	COG2402@1|root,COG2402@2|Bacteria,2IRQ5@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
REGS1_k127_8750047_12	290397.Adeh_3723	3.871e-39	145.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
REGS1_k127_8772215_0	290397.Adeh_0366	2.898e-135	434.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2YTSK@29|Myxococcales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_8772215_1	215803.DB30_1200	8.002e-05	55.0	COG5616@1|root,COG5616@2|Bacteria,1PCBD@1224|Proteobacteria,438C9@68525|delta/epsilon subdivisions,2WYM6@28221|Deltaproteobacteria,2YWIT@29|Myxococcales	28221|Deltaproteobacteria	M	cAMP biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8798631_0	404589.Anae109_1863	5.188e-131	433.0	COG0745@1|root,COG0745@2|Bacteria	404589.Anae109_1863|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8798631_2	290397.Adeh_1985	1.148e-52	194.0	COG0346@1|root,COG0346@2|Bacteria,1PY3J@1224|Proteobacteria,4352G@68525|delta/epsilon subdivisions,2WZDE@28221|Deltaproteobacteria,2Z1W6@29|Myxococcales	28221|Deltaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_8798631_4	1144275.COCOR_04447	3.383e-46	177.0	COG3018@1|root,COG3018@2|Bacteria,1R9S8@1224|Proteobacteria,42RI7@68525|delta/epsilon subdivisions,2WP0N@28221|Deltaproteobacteria,2YYF1@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
REGS1_k127_8798631_3	96561.Dole_1197	1.68e-48	188.0	28MK7@1|root,2ZAWI@2|Bacteria,1R83K@1224|Proteobacteria,42MZ5@68525|delta/epsilon subdivisions,2WKYR@28221|Deltaproteobacteria,2MISC@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8798631_5	215803.DB30_7413	2.34e-21	111.0	COG4254@1|root,COG4254@2|Bacteria,1QVB5@1224|Proteobacteria,42XP1@68525|delta/epsilon subdivisions,2X71D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
REGS1_k127_8798631_1	404589.Anae109_1873	1.655e-74	254.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,42M20@68525|delta/epsilon subdivisions,2WJ2N@28221|Deltaproteobacteria,2YWDH@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
REGS1_k127_8817684_2	404589.Anae109_1475	3.658e-50	186.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW,Response_reg
REGS1_k127_8817684_0	404589.Anae109_1474	1.349e-184	587.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42Q9F@68525|delta/epsilon subdivisions,2WMM7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_8817684_3	398527.Bphyt_4379	3.042e-38	152.0	COG3744@1|root,COG3744@2|Bacteria,1NA89@1224|Proteobacteria,2VUYN@28216|Betaproteobacteria,1KFTZ@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_8817684_4	398527.Bphyt_4380	1.105e-22	99.0	COG4118@1|root,COG4118@2|Bacteria,1NH4W@1224|Proteobacteria,2WG9U@28216|Betaproteobacteria,1KG2K@119060|Burkholderiaceae	28216|Betaproteobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_8817684_1	290397.Adeh_1153	9.583e-67	237.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,42QU8@68525|delta/epsilon subdivisions,2X5Q5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM channel protein, hemolysin III family	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
REGS1_k127_8835725_4	290397.Adeh_2116	8.551e-50	184.0	COG2974@1|root,COG2974@2|Bacteria,1N4GC@1224|Proteobacteria,42RPT@68525|delta/epsilon subdivisions,2WIWU@28221|Deltaproteobacteria,2YUX5@29|Myxococcales	28221|Deltaproteobacteria	L	Putative exonuclease, RdgC	-	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
REGS1_k127_8835725_3	290397.Adeh_2117	1.024e-71	259.0	COG2974@1|root,COG2974@2|Bacteria,1RCUH@1224|Proteobacteria,42QVW@68525|delta/epsilon subdivisions,2WN5B@28221|Deltaproteobacteria,2YVP2@29|Myxococcales	28221|Deltaproteobacteria	L	May be involved in recombination	-	-	-	-	-	-	-	-	-	-	-	-	RdgC
REGS1_k127_8835725_1	290397.Adeh_0710	9.309e-151	497.0	COG1633@1|root,COG1814@1|root,COG1633@2|Bacteria,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,42UMC@68525|delta/epsilon subdivisions,2WQJQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
REGS1_k127_8835725_2	748247.AZKH_p0561	3.261e-143	468.0	COG1775@1|root,COG1775@2|Bacteria	2|Bacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
REGS1_k127_8835725_0	748247.AZKH_p0562	6.982e-188	598.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1R411@1224|Proteobacteria,2WE9R@28216|Betaproteobacteria,2M03N@206389|Rhodocyclales	206389|Rhodocyclales	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	1.3.7.8	ko:K04114	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	M00541	R02451	RC00002,RC01839	ko00000,ko00001,ko00002,ko01000	-	-	-	BcrAD_BadFG
REGS1_k127_8865470_0	1128421.JAGA01000001_gene2399	3.011e-188	602.0	COG0179@1|root,COG0179@2|Bacteria	2|Bacteria	Q	Fumarylacetoacetate (FAA) hydrolase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iJN746.PP_4620	FAA_hydrolase,FAA_hydrolase_N
REGS1_k127_8865470_1	234267.Acid_6517	1.528e-22	99.0	COG0124@1|root,COG0124@2|Bacteria,3Y4H5@57723|Acidobacteria	57723|Acidobacteria	J	histidyl-tRNA synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8867365_2	502025.Hoch_3515	1.205e-11	72.0	2AN4U@1|root,31D2K@2|Bacteria,1QA4B@1224|Proteobacteria,434U7@68525|delta/epsilon subdivisions,2WZ56@28221|Deltaproteobacteria,2Z1CN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8867365_0	1356852.N008_10945	8.363e-72	261.0	COG0531@1|root,COG0531@2|Bacteria,4NH7J@976|Bacteroidetes,47NNC@768503|Cytophagia	976|Bacteroidetes	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
REGS1_k127_8867365_1	1082705.JIBP01000006_gene981	1.224e-23	118.0	28I6Y@1|root,2Z89T@2|Bacteria,1R4DR@1224|Proteobacteria,1RRDT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	enhanced serine sensitivity protein SseB	sseB	-	-	-	-	-	-	-	-	-	-	-	SseB,SseB_C
REGS1_k127_8867365_3	404589.Anae109_4194	1.312e-10	62.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2YVA6@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_8894976_4	404589.Anae109_2744	1.346e-119	422.0	2AJ10@1|root,319J4@2|Bacteria,1Q2X4@1224|Proteobacteria,438K5@68525|delta/epsilon subdivisions,2X3UQ@28221|Deltaproteobacteria,2YX5Z@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8894976_5	1232410.KI421424_gene1725	4.814e-117	383.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,42UE5@68525|delta/epsilon subdivisions,2WQDA@28221|Deltaproteobacteria,43W2V@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
REGS1_k127_8894976_13	882083.SacmaDRAFT_4912	2.991e-25	118.0	COG2391@1|root,COG2391@2|Bacteria,2IGU9@201174|Actinobacteria	201174|Actinobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_8894976_20	1408418.JNJH01000060_gene1184	3.804e-05	53.0	COG2391@1|root,COG2391@2|Bacteria,1MZ3A@1224|Proteobacteria,2UCDT@28211|Alphaproteobacteria,2JT8X@204441|Rhodospirillales	204441|Rhodospirillales	S	transporter component	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_8894976_3	1111479.AXAR01000002_gene1964	5.418e-123	413.0	COG0436@1|root,COG0436@2|Bacteria,1UHPJ@1239|Firmicutes,4HA5E@91061|Bacilli	91061|Bacilli	E	Aminotransferase	-	-	-	-	-	-	-	-	-	-	-	iSB619.SA_RS10050	Aminotran_1_2
REGS1_k127_8894976_1	1379270.AUXF01000004_gene2893	2.041e-239	751.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1ZV6A@142182|Gemmatimonadetes	142182|Gemmatimonadetes	P	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
REGS1_k127_8894976_12	404589.Anae109_1561	1.003e-26	116.0	COG0607@1|root,COG0607@2|Bacteria,1NGN9@1224|Proteobacteria	1224|Proteobacteria	P	phage shock operon rhodanese PspE	-	-	-	ko:K03972	-	-	-	-	ko00000	-	-	-	Rhodanese
REGS1_k127_8894976_2	290397.Adeh_0093	3.029e-227	711.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2YUDC@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_8894976_7	404589.Anae109_0095	2.993e-78	264.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2WN8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
REGS1_k127_8894976_0	404589.Anae109_0096	2.141e-246	771.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,2YXJ9@29|Myxococcales	28221|Deltaproteobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
REGS1_k127_8894976_10	382464.ABSI01000012_gene2111	7.778e-37	143.0	COG2010@1|root,COG2010@2|Bacteria,46W25@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Haem-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Haem_bd
REGS1_k127_8894976_8	290397.Adeh_0096	1.891e-63	230.0	298JI@1|root,2ZVQE@2|Bacteria,1P8JU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8894976_6	404589.Anae109_0098	3.078e-101	333.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YU2G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_8900232_0	404589.Anae109_4342	5.316e-316	979.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2YU2E@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
REGS1_k127_8900232_13	257310.BB2404	1.873e-09	65.0	2EJ23@1|root,33CT8@2|Bacteria,1NHHZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8900232_5	290397.Adeh_4194	1.696e-76	267.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WQFY@28221|Deltaproteobacteria,2YVDQ@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
REGS1_k127_8900232_11	404589.Anae109_4346	1.044e-36	142.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,2YVNJ@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
REGS1_k127_8900232_7	404589.Anae109_4347	1.055e-54	199.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42RES@68525|delta/epsilon subdivisions,2WSB9@28221|Deltaproteobacteria,2YVT4@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
REGS1_k127_8900232_1	404589.Anae109_4348	2.096e-256	799.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_8900232_4	404589.Anae109_4349	5.064e-81	273.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SED@68525|delta/epsilon subdivisions,2X5QX@28221|Deltaproteobacteria,2Z36Z@29|Myxococcales	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
REGS1_k127_8900232_3	404589.Anae109_4350	4.112e-104	343.0	COG0745@1|root,COG0745@2|Bacteria,1QXTP@1224|Proteobacteria,43C61@68525|delta/epsilon subdivisions,2X7G9@28221|Deltaproteobacteria,2YVX0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
REGS1_k127_8900232_12	1122176.KB903541_gene240	5.111e-11	74.0	COG0671@1|root,COG0671@2|Bacteria,4NR78@976|Bacteroidetes,1J0DS@117747|Sphingobacteriia	976|Bacteroidetes	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_8900232_8	404589.Anae109_4352	3.891e-42	156.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_8900232_2	290397.Adeh_4204	9.427e-164	522.0	COG1723@1|root,COG1723@2|Bacteria,1R8R9@1224|Proteobacteria,42W7V@68525|delta/epsilon subdivisions,2WS5C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8915994_15	290397.Adeh_0117	3.387e-32	128.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria,2YVPB@29|Myxococcales	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
REGS1_k127_8915994_11	290397.Adeh_0118	3.383e-57	221.0	COG0360@1|root,COG0360@2|Bacteria	2|Bacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	4.3.1.19	ko:K01754,ko:K02990	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,ko03010,map00260,map00290,map01100,map01110,map01130,map01200,map01230,map03010	M00178,M00570	R00220,R00996	RC00418,RC02600	br01610,ko00000,ko00001,ko00002,ko01000,ko03011,ko03029	-	-	-	Ribosomal_S6
REGS1_k127_8915994_8	404589.Anae109_0123	3.306e-94	311.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2WPHH@28221|Deltaproteobacteria,2YZP7@29|Myxococcales	28221|Deltaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
REGS1_k127_8915994_9	290397.Adeh_0120	6e-84	287.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2WQIY@28221|Deltaproteobacteria,2YVJV@29|Myxococcales	28221|Deltaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
REGS1_k127_8915994_4	290397.Adeh_0121	6.368e-159	506.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,2YUB9@29|Myxococcales	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
REGS1_k127_8915994_16	1121346.KB899824_gene3053	1.589e-14	85.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,4HIPT@91061|Bacilli,26Y3A@186822|Paenibacillaceae	91061|Bacilli	D	Could be involved in septation	spoVG	GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
REGS1_k127_8915994_5	290397.Adeh_0123	9.261e-124	403.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
REGS1_k127_8915994_3	290397.Adeh_0897	5.341e-167	555.0	2C0SQ@1|root,33DUT@2|Bacteria,1R7NR@1224|Proteobacteria,4319Q@68525|delta/epsilon subdivisions,2WW9H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8915994_7	290397.Adeh_0390	2.751e-108	362.0	COG0644@1|root,COG0644@2|Bacteria,1N3JT@1224|Proteobacteria,42S0W@68525|delta/epsilon subdivisions,2WVDD@28221|Deltaproteobacteria,2YU0R@29|Myxococcales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
REGS1_k127_8915994_6	404589.Anae109_1836	1.181e-115	396.0	COG3005@1|root,COG3005@2|Bacteria,1QYGG@1224|Proteobacteria,42NFU@68525|delta/epsilon subdivisions,2WKHN@28221|Deltaproteobacteria,2Z2AP@29|Myxococcales	28221|Deltaproteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_8915994_2	296591.Bpro_4151	2.476e-179	591.0	COG2176@1|root,COG5002@1|root,COG2176@2|Bacteria,COG5002@2|Bacteria,1QUVW@1224|Proteobacteria,2VHZ3@28216|Betaproteobacteria,4AD1W@80864|Comamonadaceae	28216|Betaproteobacteria	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
REGS1_k127_8915994_13	159087.Daro_1632	1.73e-46	172.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,2VT7U@28216|Betaproteobacteria,2KWBT@206389|Rhodocyclales	206389|Rhodocyclales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_8915994_0	296591.Bpro_4149	0.0	1075.0	COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VKRS@28216|Betaproteobacteria,4AAXQ@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_7,Response_reg
REGS1_k127_8915994_17	1348657.M622_01260	2.738e-10	72.0	2DNR5@1|root,32YQH@2|Bacteria,1NBXJ@1224|Proteobacteria,2VW7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8915994_10	448385.sce2156	3.232e-72	255.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42PI0@68525|delta/epsilon subdivisions,2WJ79@28221|Deltaproteobacteria,2YUU7@29|Myxococcales	28221|Deltaproteobacteria	S	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
REGS1_k127_8915994_12	215803.DB30_6374	1.247e-52	205.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456,ko:K02457,ko:K02458,ko:K02459,ko:K02655,ko:K10926	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	ComP_DUS,N_methyl
REGS1_k127_8915994_1	234267.Acid_4539	4.257e-212	687.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,3Y6VT@57723|Acidobacteria	57723|Acidobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,PTA_PTB,malic
REGS1_k127_8915994_14	444157.Tneu_1204	2.593e-34	154.0	COG0574@1|root,arCOG01111@2157|Archaea,2XPWQ@28889|Crenarchaeota	28889|Crenarchaeota	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_8915994_18	179408.Osc7112_5653	3.093e-07	64.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1G1GK@1117|Cyanobacteria,1H7JU@1150|Oscillatoriales	1117|Cyanobacteria	G	Pyruvate phosphate dikinase	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_8923572_15	404589.Anae109_3845	5.065e-76	260.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2YTX6@29|Myxococcales	28221|Deltaproteobacteria	E	Cys Met metabolism	metC	-	2.5.1.48,4.4.1.1,4.4.1.11	ko:K01739,ko:K01758,ko:K01761	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338	R00654,R00782,R00999,R01001,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00710,RC01209,RC01210,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
REGS1_k127_8923572_5	290397.Adeh_3706	6.646e-253	785.0	COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2YTZR@29|Myxococcales	28221|Deltaproteobacteria	EK	Pyridoxal-phosphate dependent enzyme	-	-	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
REGS1_k127_8923572_10	404589.Anae109_3847	8.768e-172	546.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42N6V@68525|delta/epsilon subdivisions,2WIQC@28221|Deltaproteobacteria,2Z2Y7@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH,NTP_transferase
REGS1_k127_8923572_0	404589.Anae109_3836	3.241e-276	856.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2WK5T@28221|Deltaproteobacteria,2YWIX@29|Myxococcales	28221|Deltaproteobacteria	S	Sodium:solute symporter family	aplA	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	iAF987.Gmet_0739	SSF
REGS1_k127_8923572_18	404589.Anae109_3835	8.181e-31	125.0	COG3162@1|root,COG3162@2|Bacteria,1MZF3@1224|Proteobacteria,42VY2@68525|delta/epsilon subdivisions,2WRI2@28221|Deltaproteobacteria,2Z2FS@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
REGS1_k127_8923572_3	404589.Anae109_3352	6.689e-261	814.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,42QW3@68525|delta/epsilon subdivisions,2WNT9@28221|Deltaproteobacteria,2YWWY@29|Myxococcales	28221|Deltaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
REGS1_k127_8923572_8	404589.Anae109_3834	9.23e-198	626.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,42PAX@68525|delta/epsilon subdivisions,2WKEP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
REGS1_k127_8923572_19	1121890.AUDO01000012_gene2304	6.134e-26	110.0	COG4327@1|root,COG4327@2|Bacteria,4NSV7@976|Bacteroidetes,1I3X5@117743|Flavobacteriia,2NX5R@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
REGS1_k127_8923572_4	404589.Anae109_3832	9.954e-260	812.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria,2YZK2@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
REGS1_k127_8923572_2	1144325.PMI22_02538	3.75e-261	814.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,1S174@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
REGS1_k127_8923572_9	290397.Adeh_3699	1.389e-178	584.0	COG0515@1|root,COG0589@1|root,COG0515@2|Bacteria,COG0589@2|Bacteria,1MV1P@1224|Proteobacteria,42VSC@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Protein tyrosine kinase	MA20_09295	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Usp
REGS1_k127_8923572_14	290397.Adeh_3700	5.517e-91	305.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,42RNB@68525|delta/epsilon subdivisions,2WNEW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
REGS1_k127_8923572_22	404589.Anae109_1794	6.8e-06	53.0	2A4V7@1|root,30TGT@2|Bacteria,1PDBB@1224|Proteobacteria,43E5P@68525|delta/epsilon subdivisions,2WZT2@28221|Deltaproteobacteria,2Z2PJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPW
REGS1_k127_8923572_7	404589.Anae109_3825	2.579e-227	719.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
REGS1_k127_8923572_1	404589.Anae109_3824	2.324e-262	820.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NAX@68525|delta/epsilon subdivisions,2WJF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
REGS1_k127_8923572_16	404589.Anae109_3823	3.283e-75	275.0	COG0847@1|root,COG0847@2|Bacteria,1RAF1@1224|Proteobacteria,42W6M@68525|delta/epsilon subdivisions,2WS2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
REGS1_k127_8923572_13	290397.Adeh_3693	4.357e-133	437.0	COG2270@1|root,COG2270@2|Bacteria,1QX9I@1224|Proteobacteria,43C2R@68525|delta/epsilon subdivisions,2X7DB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleoside H+ symporter	-	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
REGS1_k127_8923572_12	290397.Adeh_3692	2.768e-152	488.0	COG1208@1|root,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,2Z2Y6@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
REGS1_k127_8923572_6	290397.Adeh_3664	1.043e-238	745.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2YU8U@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
REGS1_k127_8923572_11	316067.Geob_3549	3.039e-165	522.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,43UBB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
REGS1_k127_8939642_1	290397.Adeh_3468	4.711e-84	295.0	2AGT8@1|root,3171A@2|Bacteria,1PY9M@1224|Proteobacteria,4356T@68525|delta/epsilon subdivisions,2WZHY@28221|Deltaproteobacteria,2Z26Q@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8939642_0	290397.Adeh_3469	9.694e-145	463.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2WJS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
REGS1_k127_8970291_9	330214.NIDE1161	2.569e-12	76.0	COG1266@1|root,COG1633@1|root,COG1266@2|Bacteria,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594,ko:K07052	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Abi
REGS1_k127_8970291_10	426117.M446_3263	2.366e-06	57.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,2TU3A@28211|Alphaproteobacteria,1JV3K@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PFAM Mandelate racemase muconate lactonizing	-	-	4.2.1.156,4.2.1.42	ko:K20023	ko00053,map00053	-	R05608	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
REGS1_k127_8970291_2	1110502.TMO_2845	6.793e-106	353.0	COG0687@1|root,COG0687@2|Bacteria,1MWG5@1224|Proteobacteria,2TTP2@28211|Alphaproteobacteria,2JRUN@204441|Rhodospirillales	204441|Rhodospirillales	E	Bacterial extracellular solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
REGS1_k127_8970291_3	1510531.JQJJ01000002_gene5032	9.869e-99	336.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQMJ@28211|Alphaproteobacteria,3JRKH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02049,ko:K02052	ko02024,map02024	M00188,M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11,3.A.1.16,3.A.1.17	-	-	ABC_tran,TOBE_2
REGS1_k127_8970291_4	1510531.JQJJ01000002_gene5033	7.727e-94	317.0	COG1176@1|root,COG1176@2|Bacteria,1MVFG@1224|Proteobacteria,2TSSR@28211|Alphaproteobacteria,3JQXE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02054	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_8970291_7	1510531.JQJJ01000002_gene5034	6.109e-75	275.0	COG1177@1|root,COG1177@2|Bacteria,1MZ2N@1224|Proteobacteria,2U3ZP@28211|Alphaproteobacteria,3JT39@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
REGS1_k127_8970291_5	1502851.FG93_00197	8.086e-84	287.0	COG1028@1|root,COG1028@2|Bacteria,1MU2T@1224|Proteobacteria,2TSDG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100,1.1.1.36	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	M00083,M00373,M00572	R01779,R01977,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00103,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_8970291_6	1532557.JL37_17400	2.021e-78	269.0	COG1028@1|root,COG1028@2|Bacteria,1MV44@1224|Proteobacteria,2VJH7@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	short-chain dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
REGS1_k127_8970291_1	1110502.TMO_2841	1.061e-127	413.0	COG0726@1|root,COG0726@2|Bacteria,1MV3V@1224|Proteobacteria,2TR0I@28211|Alphaproteobacteria,2JQCA@204441|Rhodospirillales	204441|Rhodospirillales	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_8970291_0	935565.JAEM01000018_gene1045	2.43e-145	478.0	COG0154@1|root,COG0154@2|Bacteria,1MW3Z@1224|Proteobacteria,2TS56@28211|Alphaproteobacteria,2PV40@265|Paracoccus	28211|Alphaproteobacteria	J	Belongs to the amidase family	MA20_14695	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
REGS1_k127_8970291_8	1038867.AXAY01000008_gene445	6.147e-25	106.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,2TT1G@28211|Alphaproteobacteria,3JQQ7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_9156763_4	378806.STAUR_7897	1.044e-105	359.0	COG0784@1|root,COG2202@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WUVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
REGS1_k127_9156763_1	290397.Adeh_4242	1.139e-204	649.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,2YWP2@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsA	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
REGS1_k127_9156763_0	290397.Adeh_4240	1.087e-226	711.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4M@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	sasR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_9156763_8	378806.STAUR_1859	7.473e-19	98.0	2AIZ1@1|root,319GZ@2|Bacteria,1Q2R0@1224|Proteobacteria,438CI@68525|delta/epsilon subdivisions,2X3MV@28221|Deltaproteobacteria,2YWJN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9156763_2	1144275.COCOR_06912	2.27e-161	534.0	COG2206@1|root,COG3437@1|root,COG2206@2|Bacteria,COG3437@2|Bacteria,1MV37@1224|Proteobacteria,42N4N@68525|delta/epsilon subdivisions,2WKJ1@28221|Deltaproteobacteria,2YU9U@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HD,HD_5
REGS1_k127_9156763_5	290397.Adeh_4231	2.355e-83	297.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,42VWF@68525|delta/epsilon subdivisions,2WRX8@28221|Deltaproteobacteria,2YVKZ@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
REGS1_k127_9156763_3	404589.Anae109_4379	8.034e-155	506.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YWPQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
REGS1_k127_9164671_2	290397.Adeh_3637	4.387e-38	149.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria,2YUDA@29|Myxococcales	28221|Deltaproteobacteria	H	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
REGS1_k127_9164671_1	290397.Adeh_3636	3.821e-40	151.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,42TGQ@68525|delta/epsilon subdivisions,2WQ6R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
REGS1_k127_9164671_0	290397.Adeh_3635	3.301e-104	350.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2YYNH@29|Myxococcales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
REGS1_k127_9168674_2	290397.Adeh_0872	2.995e-61	213.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1RE8Z@1224|Proteobacteria,42VZV@68525|delta/epsilon subdivisions,2WRHV@28221|Deltaproteobacteria,2YWGA@29|Myxococcales	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
REGS1_k127_9168674_0	404589.Anae109_0930	4.173e-142	465.0	COG0745@1|root,COG0745@2|Bacteria,1QYFT@1224|Proteobacteria,43CBY@68525|delta/epsilon subdivisions,2X7MT@28221|Deltaproteobacteria,2Z3GV@29|Myxococcales	28221|Deltaproteobacteria	T	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE_N
REGS1_k127_9168674_1	386456.JQKN01000015_gene2938	5.295e-75	268.0	COG3174@1|root,arCOG04203@2157|Archaea,2XT0W@28890|Euryarchaeota	28890|Euryarchaeota	P	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
REGS1_k127_936138_1	215803.DB30_7046	3.715e-258	820.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,42MSV@68525|delta/epsilon subdivisions,2WJ6U@28221|Deltaproteobacteria,2YUNP@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
REGS1_k127_936138_0	215803.DB30_7047	0.0	1111.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,42MJ8@68525|delta/epsilon subdivisions,2WIVP@28221|Deltaproteobacteria,2YUDK@29|Myxococcales	28221|Deltaproteobacteria	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1,Thiol-ester_cl
REGS1_k127_988183_1	404589.Anae109_4269	3.045e-242	753.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,2YWT1@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
REGS1_k127_988183_9	404589.Anae109_4270	2.094e-73	254.0	COG0494@1|root,COG0494@2|Bacteria,1N99N@1224|Proteobacteria,43CD1@68525|delta/epsilon subdivisions,2X7NW@28221|Deltaproteobacteria,2Z2NN@29|Myxococcales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_988183_17	1278073.MYSTI_03668	9.126e-20	98.0	2C8CB@1|root,2ZGCM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_988183_19	290397.Adeh_4119	2.591e-15	76.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H,Response_reg
REGS1_k127_988183_13	404589.Anae109_4278	1.295e-52	191.0	COG0509@1|root,COG0509@2|Bacteria	2|Bacteria	E	glycine decarboxylation via glycine cleavage system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H,Response_reg
REGS1_k127_988183_18	215803.DB30_2016	2.753e-19	101.0	2C7SF@1|root,31FYA@2|Bacteria,1QDQG@1224|Proteobacteria,439BY@68525|delta/epsilon subdivisions,2X4JZ@28221|Deltaproteobacteria,2YZ5Z@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_988183_12	404589.Anae109_4284	1.891e-61	218.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_988183_3	404589.Anae109_2889	2.357e-100	334.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	2.1.1.72	ko:K00571,ko:K03497	-	-	-	-	ko00000,ko01000,ko02048,ko03000,ko03036,ko04812	-	-	-	N6_N4_Mtase,ParBc,RE_Eco29kI
REGS1_k127_988183_6	443143.GM18_1315	7.524e-78	288.0	2AEFS@1|root,314AU@2|Bacteria,1RKTV@1224|Proteobacteria,42YDD@68525|delta/epsilon subdivisions,2WUI4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_988183_2	443143.GM18_1316	5.186e-107	355.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,42YBW@68525|delta/epsilon subdivisions,2WUJC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_988183_0	290397.Adeh_4143	0.0	1095.0	COG4258@1|root,COG4258@2|Bacteria,1QX7Z@1224|Proteobacteria,43C13@68525|delta/epsilon subdivisions,2X7BR@28221|Deltaproteobacteria,2YU55@29|Myxococcales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
REGS1_k127_988183_15	1499967.BAYZ01000105_gene3475	5.832e-38	158.0	28UH1@1|root,2ZGMU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
REGS1_k127_988183_7	404589.Anae109_3154	1.762e-77	263.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42RFX@68525|delta/epsilon subdivisions,2WN92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_988183_11	290397.Adeh_3382	2.654e-66	235.0	COG3850@1|root,COG3850@2|Bacteria,1N013@1224|Proteobacteria,42Z7D@68525|delta/epsilon subdivisions,2WURU@28221|Deltaproteobacteria	1224|Proteobacteria	T	Double sensory domain of two-component sensor kinase	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
REGS1_k127_988183_5	290397.Adeh_4145	1.308e-81	294.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DAGAT
REGS1_k127_988183_8	290397.Adeh_4146	7.818e-77	271.0	COG0204@1|root,COG0204@2|Bacteria	2|Bacteria	I	Acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,DAGAT
REGS1_k127_988183_14	290397.Adeh_4147	2.276e-42	159.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	pimA	GO:0000026,GO:0000030,GO:0000287,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006644,GO:0006650,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0043167,GO:0043169,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046486,GO:0046488,GO:0046872,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
## 3517 queries scanned
## Total time (seconds): 731.8120617866516
## Rate: 4.81 q/s