## Tue Nov 12 07:23:41 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/R/REGS1_bin.41.fa -m mmseqs --itype genome -o REGS1_bin.41 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/REGS1_bin.41 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
REGS1_k127_1009457_19	439235.Dalk_5269	1.226e-39	169.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R09K@1224|Proteobacteria	1224|Proteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2
REGS1_k127_1009457_4	243231.GSU0606	1.165e-186	588.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,43TGR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
REGS1_k127_1009457_5	269799.Gmet_2909	3.622e-181	579.0	COG0351@1|root,COG0352@1|root,COG0351@2|Bacteria,COG0352@2|Bacteria,1MU9J@1224|Proteobacteria,42N1F@68525|delta/epsilon subdivisions,2WK2V@28221|Deltaproteobacteria,43T5P@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiD	-	2.5.1.3,2.7.1.49,2.7.4.7	ko:K00941,ko:K14153,ko:K21219	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2909	Phos_pyr_kin,TMP-TENI,ThiP_synth
REGS1_k127_1009457_0	269799.Gmet_2910	5.695e-253	783.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,42MMB@68525|delta/epsilon subdivisions,2WJEI@28221|Deltaproteobacteria,43U11@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2910	ThiC_Rad_SAM
REGS1_k127_1009457_24	1500893.JQNB01000001_gene1582	1.441e-25	122.0	2DS2B@1|root,33E7G@2|Bacteria,1PYQR@1224|Proteobacteria,1T73Q@1236|Gammaproteobacteria,1X8QG@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1009457_14	1173028.ANKO01000199_gene3514	1.316e-48	192.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,1HBYM@1150|Oscillatoriales	1117|Cyanobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_1009457_16	243231.GSU0877	1.382e-44	172.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
REGS1_k127_1009457_17	243231.GSU0877	4.347e-42	164.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
REGS1_k127_1009457_1	269799.Gmet_0504	1.539e-245	771.0	COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria,1NPFY@1224|Proteobacteria,42PRW@68525|delta/epsilon subdivisions,2WIMG@28221|Deltaproteobacteria,43SUD@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylenetetrahydrofolate reductase	metF-2	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0504	MTHFR,S-methyl_trans
REGS1_k127_1009457_25	665952.HMPREF1015_01010	9.365e-08	57.0	COG1923@1|root,COG1923@2|Bacteria,1VEGI@1239|Firmicutes,4HNN2@91061|Bacilli,1ZHYZ@1386|Bacillus	91061|Bacilli	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
REGS1_k127_1009457_15	316067.Geob_2960	5.846e-45	165.0	COG3549@1|root,COG3549@2|Bacteria,1MZ4I@1224|Proteobacteria,42VTK@68525|delta/epsilon subdivisions,2WSDM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
REGS1_k127_1009457_18	316067.Geob_2961	1.96e-40	152.0	COG3093@1|root,COG3093@2|Bacteria,1N2BD@1224|Proteobacteria,42TY5@68525|delta/epsilon subdivisions,2WQN7@28221|Deltaproteobacteria,43VPZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
REGS1_k127_1009457_9	404380.Gbem_3532	5.626e-94	316.0	COG1108@1|root,COG1108@2|Bacteria,1MVC2@1224|Proteobacteria,42MYM@68525|delta/epsilon subdivisions,2WJAM@28221|Deltaproteobacteria,43UC9@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816,ko:K09819	ko02010,map02010	M00242,M00243	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
REGS1_k127_1009457_21	443144.GM21_3211	4.309e-33	147.0	COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,42RRN@68525|delta/epsilon subdivisions,2WNAY@28221|Deltaproteobacteria,43SI2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1009457_11	335543.Sfum_1199	1.483e-85	303.0	COG1807@1|root,COG1807@2|Bacteria,1R3XN@1224|Proteobacteria,42P5N@68525|delta/epsilon subdivisions,2WKH2@28221|Deltaproteobacteria,2MQ8W@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_1009457_10	398767.Glov_1834	9.284e-93	312.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2WKMZ@28221|Deltaproteobacteria,43U5P@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM ABC transporter related	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
REGS1_k127_1009457_8	269799.Gmet_0491	6.241e-100	336.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WQYR@28221|Deltaproteobacteria,43TDX@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	acdA	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
REGS1_k127_1009457_7	316067.Geob_1865	2.77e-126	424.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,43SJD@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp64H-2	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
REGS1_k127_1009457_23	316067.Geob_0908	1.525e-27	117.0	COG0457@1|root,COG0457@2|Bacteria,1P4QM@1224|Proteobacteria,4334V@68525|delta/epsilon subdivisions,2WX62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
REGS1_k127_1009457_13	243231.GSU1056	3.061e-55	196.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TJK@68525|delta/epsilon subdivisions,2WQ0Z@28221|Deltaproteobacteria,43SPB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
REGS1_k127_1009457_22	316067.Geob_0928	2.02e-28	119.0	294M8@1|root,34B0H@2|Bacteria,1P2RM@1224|Proteobacteria,43174@68525|delta/epsilon subdivisions,2WWJZ@28221|Deltaproteobacteria,43VJJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
REGS1_k127_1009457_2	316067.Geob_0931	1.941e-227	710.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria,43TA7@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM aminotransferase, class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_1009457_3	316067.Geob_3044	6.817e-217	679.0	COG1914@1|root,COG1914@2|Bacteria,1N0XH@1224|Proteobacteria,43B4Q@68525|delta/epsilon subdivisions,2X6IC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
REGS1_k127_1009457_6	316067.Geob_3043	5.465e-171	546.0	COG2239@1|root,COG2239@2|Bacteria,1RFCV@1224|Proteobacteria,42S1B@68525|delta/epsilon subdivisions,2WP0D@28221|Deltaproteobacteria,43VZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	MgtE intracellular N domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,MgtE_N,PRC
REGS1_k127_1009457_26	169963.lmo2689a	6.935e-05	45.0	2CH13@1|root,2ZVZ3@2|Bacteria,1W3Q9@1239|Firmicutes,4I1JU@91061|Bacilli,26MWH@186820|Listeriaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1009457_20	243231.GSU0118	6.25e-35	140.0	2FEX4@1|root,346VX@2|Bacteria,1P00J@1224|Proteobacteria,4314J@68525|delta/epsilon subdivisions,2WWBY@28221|Deltaproteobacteria,43VIK@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1009457_12	316067.Geob_0933	5.657e-59	210.0	COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,42UA5@68525|delta/epsilon subdivisions,2WQWH@28221|Deltaproteobacteria,43SMP@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1060247_2	243231.GSU1923	7.153e-102	344.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,42N5X@68525|delta/epsilon subdivisions,2WJ3H@28221|Deltaproteobacteria,43TT8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted permease YjgP/YjgQ family	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
REGS1_k127_1060247_1	316067.Geob_1523	7.987e-113	379.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,42NYD@68525|delta/epsilon subdivisions,2WKHT@28221|Deltaproteobacteria,43T2W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
REGS1_k127_1060247_0	269799.Gmet_1250	2.614e-127	415.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,43SZ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
REGS1_k127_1060247_3	398767.Glov_2709	6.51e-11	62.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,43S6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
REGS1_k127_1173048_0	338966.Ppro_3650	0.0	1675.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,43U5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
REGS1_k127_1173048_7	398767.Glov_3080	3.011e-59	208.0	2EHTJ@1|root,33BJ7@2|Bacteria,1NHGC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1173048_13	555779.Dthio_PD0818	7.685e-32	133.0	2DWTV@1|root,341UQ@2|Bacteria,1Q1EI@1224|Proteobacteria,4377N@68525|delta/epsilon subdivisions,2X1HS@28221|Deltaproteobacteria,2MF38@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Lipid A 3-O-deacylase-related	-	-	-	-	-	-	-	-	-	-	-	-	PagL
REGS1_k127_1173048_11	290318.Cvib_0601	6.927e-41	157.0	COG0671@1|root,COG0671@2|Bacteria,1FFMA@1090|Chlorobi	1090|Chlorobi	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_1173048_4	338966.Ppro_2480	4.406e-176	563.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,43SZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_1173048_9	398767.Glov_0072	5.197e-50	182.0	COG3305@1|root,COG3305@2|Bacteria,1NA3D@1224|Proteobacteria	1224|Proteobacteria	S	Predicted membrane protein (DUF2127)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2127
REGS1_k127_1173048_12	396588.Tgr7_0591	8.014e-40	151.0	COG1694@1|root,COG1694@2|Bacteria,1N02D@1224|Proteobacteria,1S8RW@1236|Gammaproteobacteria,1X2HD@135613|Chromatiales	135613|Chromatiales	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
REGS1_k127_1173048_5	1232410.KI421426_gene1425	4.705e-118	389.0	COG0324@1|root,COG0324@2|Bacteria,1R5TR@1224|Proteobacteria,42P8W@68525|delta/epsilon subdivisions,2WMB5@28221|Deltaproteobacteria,43RYV@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA-2	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
REGS1_k127_1173048_6	1232410.KI421426_gene1426	1.391e-106	359.0	COG1215@1|root,COG1215@2|Bacteria,1RA3Y@1224|Proteobacteria,42P2V@68525|delta/epsilon subdivisions,2WKVR@28221|Deltaproteobacteria,43RXJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1173048_2	932678.THERU_02010	1.211e-205	661.0	COG1629@1|root,COG4771@2|Bacteria,2G5I0@200783|Aquificae	200783|Aquificae	P	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
REGS1_k127_1173048_8	243233.MCA0430	1.677e-58	213.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4,Fer4_4,Fer4_5,Fer4_7,Fer4_9
REGS1_k127_1173048_14	398767.Glov_3668	3.501e-30	129.0	COG0810@1|root,COG0810@2|Bacteria,1N94H@1224|Proteobacteria,42V43@68525|delta/epsilon subdivisions,2WRRA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
REGS1_k127_1173048_10	395019.Bmul_5093	5.464e-42	159.0	2E1Y1@1|root,32X6X@2|Bacteria,1N67Q@1224|Proteobacteria,2VVJX@28216|Betaproteobacteria,1K8KU@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1173048_3	56780.SYN_02911	3.098e-195	615.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2X9WU@28221|Deltaproteobacteria,2MRQN@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
REGS1_k127_1173048_15	1304885.AUEY01000139_gene211	3.924e-22	98.0	COG3311@1|root,COG3311@2|Bacteria,1NGB9@1224|Proteobacteria,4317M@68525|delta/epsilon subdivisions,2WWRY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Prophage CP4-57 regulatory protein (AlpA)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_AlpA
REGS1_k127_1173048_1	56780.SYN_00697	3.136e-215	677.0	COG0358@1|root,COG0358@2|Bacteria	2|Bacteria	L	DNA primase activity	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	AAA_25,DUF3987,DnaB_C,Toprim_2,Toprim_4
REGS1_k127_1186988_5	316067.Geob_3587	1.57e-29	118.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_1186988_6	243231.GSU1042	4.204e-25	109.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_1186988_3	522306.CAP2UW1_3322	1.779e-47	175.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,1KQUT@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_1186988_2	338966.Ppro_0418	2.309e-103	345.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria,43T3T@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
REGS1_k127_1186988_1	338966.Ppro_0417	1.19e-106	361.0	COG3064@1|root,COG3064@2|Bacteria,1MXPS@1224|Proteobacteria,42PA3@68525|delta/epsilon subdivisions,2WM6X@28221|Deltaproteobacteria,43SGF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
REGS1_k127_1186988_4	1123371.ATXH01000003_gene1973	3.412e-30	124.0	COG1254@1|root,COG1254@2|Bacteria,2GHZK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
REGS1_k127_1186988_0	243231.GSU0890	2.078e-310	960.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,43TM8@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
REGS1_k127_123216_5	269799.Gmet_2148	6.137e-33	132.0	292UM@1|root,338CY@2|Bacteria,1NAKE@1224|Proteobacteria,42WM1@68525|delta/epsilon subdivisions,2WS0V@28221|Deltaproteobacteria,43T5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_123216_0	443143.GM18_4130	1.856e-155	498.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,42MXJ@68525|delta/epsilon subdivisions,2WKAC@28221|Deltaproteobacteria,43UFU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	acuI	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_123216_6	398767.Glov_0198	1.625e-30	121.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	frx-5	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
REGS1_k127_123216_2	1380394.JADL01000002_gene1082	2.997e-96	323.0	COG2084@1|root,COG2084@2|Bacteria,1P0X0@1224|Proteobacteria,2U255@28211|Alphaproteobacteria,2JT1E@204441|Rhodospirillales	204441|Rhodospirillales	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
REGS1_k127_123216_3	316067.Geob_3787	1.573e-73	252.0	COG1633@1|root,COG1633@2|Bacteria,1RM4Q@1224|Proteobacteria,42SRM@68525|delta/epsilon subdivisions,2WP47@28221|Deltaproteobacteria,43SJC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_123216_4	338966.Ppro_3686	6.389e-63	218.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,42VVC@68525|delta/epsilon subdivisions,2WRH9@28221|Deltaproteobacteria,43V0N@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
REGS1_k127_123216_1	269799.Gmet_2760	4.04e-128	412.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42MHF@68525|delta/epsilon subdivisions,2WJ1R@28221|Deltaproteobacteria,43SF0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
REGS1_k127_1238541_0	316067.Geob_0260	1.498e-312	965.0	COG2414@1|root,COG2414@2|Bacteria,1R76Y@1224|Proteobacteria,42QE3@68525|delta/epsilon subdivisions,2WIIW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
REGS1_k127_1238541_10	404589.Anae109_3662	1.294e-62	218.0	COG3832@1|root,COG3832@2|Bacteria,1RJ9N@1224|Proteobacteria,431P8@68525|delta/epsilon subdivisions,2WWA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
REGS1_k127_1238541_4	666685.R2APBS1_0246	9.685e-113	366.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,1S2TQ@1236|Gammaproteobacteria,1X4M1@135614|Xanthomonadales	135614|Xanthomonadales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_1238541_9	1356854.N007_18995	9.008e-72	258.0	COG0477@1|root,COG2814@2|Bacteria,1UY2P@1239|Firmicutes,4HF7P@91061|Bacilli	91061|Bacilli	EGP	of the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_4
REGS1_k127_1238541_13	269799.Gmet_2491	5.185e-49	177.0	COG5499@1|root,COG5499@2|Bacteria,1MZHS@1224|Proteobacteria,42QF1@68525|delta/epsilon subdivisions,2WSAA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	ko:K18831	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_3
REGS1_k127_1238541_14	443143.GM18_2333	9.242e-43	158.0	COG4680@1|root,COG4680@2|Bacteria,1N036@1224|Proteobacteria,42VA0@68525|delta/epsilon subdivisions,2WS1B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system	-	-	-	ko:K19166	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HigB_toxin
REGS1_k127_1238541_8	243231.GSU0196	2.131e-80	269.0	COG2050@1|root,COG2050@2|Bacteria,1NHB0@1224|Proteobacteria,42XCC@68525|delta/epsilon subdivisions,2WTEP@28221|Deltaproteobacteria,43UMX@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_1238541_5	404380.Gbem_1510	6.314e-108	355.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,43SF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
REGS1_k127_1238541_19	269799.Gmet_2643	0.0004604	43.0	COG1893@1|root,COG1893@2|Bacteria,1RFSW@1224|Proteobacteria,43AIX@68525|delta/epsilon subdivisions,2X5Z6@28221|Deltaproteobacteria,43T9T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2643	ApbA,ApbA_C
REGS1_k127_1238541_18	1121439.dsat_0273	0.0003578	51.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42T39@68525|delta/epsilon subdivisions,2WPHT@28221|Deltaproteobacteria,2MAAM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_1238541_11	1283300.ATXB01000001_gene450	4.13e-59	224.0	COG0790@1|root,COG4249@1|root,COG4372@1|root,COG0790@2|Bacteria,COG4249@2|Bacteria,COG4372@2|Bacteria,1MWPA@1224|Proteobacteria,1RRKA@1236|Gammaproteobacteria,1XDWF@135618|Methylococcales	135618|Methylococcales	M	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Sel1
REGS1_k127_1238541_17	941449.dsx2_1314	0.0002051	52.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42T39@68525|delta/epsilon subdivisions,2WPHT@28221|Deltaproteobacteria,2MAAM@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_1238541_6	589865.DaAHT2_0221	3.363e-102	348.0	COG2172@1|root,COG2208@1|root,COG5002@1|root,COG2172@2|Bacteria,COG2208@2|Bacteria,COG5002@2|Bacteria,1PGCN@1224|Proteobacteria,42ZJ2@68525|delta/epsilon subdivisions,2WUYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Stage II sporulation E family protein	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
REGS1_k127_1238541_2	316067.Geob_3726	4.72e-217	688.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42NCR@68525|delta/epsilon subdivisions,2WKMY@28221|Deltaproteobacteria,43T6P@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_1238541_3	443144.GM21_2788	4.36e-166	532.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,43TQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
REGS1_k127_1238541_1	316067.Geob_0247	4.445e-221	689.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,43T89@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2261	ATP-grasp_2,Ligase_CoA
REGS1_k127_1238541_15	1089548.KI783301_gene889	1.437e-35	145.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4HC5V@91061|Bacilli	91061|Bacilli	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
REGS1_k127_1238541_12	401526.TcarDRAFT_0620	1.468e-50	188.0	COG1273@1|root,COG1273@2|Bacteria,1TSY5@1239|Firmicutes,4H2SP@909932|Negativicutes	909932|Negativicutes	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
REGS1_k127_1238541_7	706587.Desti_0133	2.465e-86	298.0	COG3285@1|root,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,42Z1A@68525|delta/epsilon subdivisions,2WU2C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
REGS1_k127_1268901_4	316067.Geob_3274	4.096e-88	297.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,42Q5T@68525|delta/epsilon subdivisions,2WUTJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
REGS1_k127_1268901_3	1121918.ARWE01000001_gene2501	8.641e-98	338.0	COG0642@1|root,COG0642@2|Bacteria,1NXDJ@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07716,ko:K20974	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511,M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	CHASE,CHASE3,HATPase_c,HisKA,PAS_7,Response_reg
REGS1_k127_1268901_0	404380.Gbem_0285	1.039e-194	611.0	COG2768@1|root,COG2768@2|Bacteria,1MXMK@1224|Proteobacteria,42M2Z@68525|delta/epsilon subdivisions,2WIN6@28221|Deltaproteobacteria,43UG2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_4,Fer4_6,Fer4_7
REGS1_k127_1268901_2	316067.Geob_1377	1.421e-100	332.0	COG0784@1|root,COG0784@2|Bacteria,1NR4Q@1224|Proteobacteria,42YGU@68525|delta/epsilon subdivisions,2WTXD@28221|Deltaproteobacteria,43TXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1268901_1	316067.Geob_1718	2.553e-130	424.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,43U4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
REGS1_k127_1273935_40	398767.Glov_0163	5.273e-38	148.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WKYQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	TIGRFAM para-aminobenzoate synthase, subunit I	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
REGS1_k127_1273935_6	398767.Glov_0162	3.082e-150	486.0	COG1538@1|root,COG1538@2|Bacteria,1QY91@1224|Proteobacteria,42Q4F@68525|delta/epsilon subdivisions,2WJMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_1273935_30	748247.AZKH_0469	2.338e-60	223.0	COG1840@1|root,COG1840@2|Bacteria,1MY20@1224|Proteobacteria,2VJ69@28216|Betaproteobacteria,2KYC6@206389|Rhodocyclales	28216|Betaproteobacteria	P	Bacterial extracellular solute-binding protein	afuA	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_6,SBP_bac_8
REGS1_k127_1273935_27	316067.Geob_1085	2.49e-66	230.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,42RE5@68525|delta/epsilon subdivisions,2WNNI@28221|Deltaproteobacteria,43V2V@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SEC-C motif	-	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
REGS1_k127_1273935_39	398767.Glov_3454	5.518e-39	147.0	2E3DE@1|root,32YCK@2|Bacteria	2|Bacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
REGS1_k127_1273935_36	243231.GSU3293	2.38e-50	184.0	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_1273935_24	243231.GSU0208	2.284e-72	252.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
REGS1_k127_1273935_17	1232410.KI421413_gene480	9.377e-107	353.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WMGU@28221|Deltaproteobacteria,43W0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Shikimate dehydrogenase substrate binding domain	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
REGS1_k127_1273935_31	96561.Dole_3110	9.783e-58	208.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42TW3@68525|delta/epsilon subdivisions,2WPZS@28221|Deltaproteobacteria,2MKHQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
REGS1_k127_1273935_41	316067.Geob_1362	2.253e-37	143.0	2FKH0@1|root,34C47@2|Bacteria,1P01G@1224|Proteobacteria,4319N@68525|delta/epsilon subdivisions,2WX29@28221|Deltaproteobacteria,43VDF@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1273935_44	316067.Geob_1359	5.355e-26	109.0	2EJCJ@1|root,33D3K@2|Bacteria,1NJJB@1224|Proteobacteria,42WV8@68525|delta/epsilon subdivisions,2WT6H@28221|Deltaproteobacteria,43SSR@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	dhc2	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1273935_28	443144.GM21_0384	6.608e-66	230.0	COG4900@1|root,COG4900@2|Bacteria,1NQAA@1224|Proteobacteria,42X8V@68525|delta/epsilon subdivisions,2WT0I@28221|Deltaproteobacteria,43V8W@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1273935_21	316067.Geob_0705	5.947e-84	285.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1273935_4	243231.GSU0486	3.339e-199	628.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,42MKY@68525|delta/epsilon subdivisions,2WM9K@28221|Deltaproteobacteria,43S98@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	tdcB	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_1273935_33	269799.Gmet_3073	4.055e-55	201.0	COG3222@1|root,COG3222@2|Bacteria,1RHCP@1224|Proteobacteria,43B9I@68525|delta/epsilon subdivisions,2X6NN@28221|Deltaproteobacteria,43SK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Guanylyl transferase CofC like	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
REGS1_k127_1273935_11	269799.Gmet_3074	9.371e-135	434.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,42N4U@68525|delta/epsilon subdivisions,2WJR7@28221|Deltaproteobacteria,43TUX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Converts GTP to 7,8-dihydroneopterin triphosphate	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
REGS1_k127_1273935_12	269799.Gmet_3075	8.934e-129	416.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,42MKZ@68525|delta/epsilon subdivisions,2WING@28221|Deltaproteobacteria,43SWX@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_3075	QueC
REGS1_k127_1273935_42	118005.AWNK01000001_gene1826	4.685e-37	152.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	HATPase_c,HisKA,Phosphonate-bd
REGS1_k127_1273935_9	316067.Geob_1937	9.416e-146	471.0	COG1463@1|root,COG1463@2|Bacteria,1MY8D@1224|Proteobacteria,42TCA@68525|delta/epsilon subdivisions,2WP6I@28221|Deltaproteobacteria,43TRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
REGS1_k127_1273935_15	316067.Geob_1938	6.36e-114	372.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2WUPA@28221|Deltaproteobacteria,43U8E@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
REGS1_k127_1273935_16	243231.GSU0924	2.725e-109	358.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,43B0R@68525|delta/epsilon subdivisions,2X6ET@28221|Deltaproteobacteria,43TJD@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
REGS1_k127_1273935_2	269799.Gmet_2545	2.67e-286	891.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,43TDR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
REGS1_k127_1273935_19	1049564.TevJSym_br00100	1.083e-88	304.0	COG1215@1|root,COG1215@2|Bacteria,1RA75@1224|Proteobacteria,1S3RM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1273935_23	398767.Glov_1979	2.481e-83	282.0	292MF@1|root,2ZQ5C@2|Bacteria,1RCYR@1224|Proteobacteria,42RFG@68525|delta/epsilon subdivisions,2WPKN@28221|Deltaproteobacteria,43UW5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3047)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3047
REGS1_k127_1273935_13	243231.GSU1312	3.337e-126	412.0	COG0535@1|root,COG0535@2|Bacteria,1MU07@1224|Proteobacteria,42QKH@68525|delta/epsilon subdivisions,2WMW7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3641,Fer4_12,Radical_SAM
REGS1_k127_1273935_32	243231.GSU1313	1.525e-57	201.0	COG0599@1|root,COG0599@2|Bacteria,1NBJR@1224|Proteobacteria,42SYS@68525|delta/epsilon subdivisions,2WPQD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
REGS1_k127_1273935_18	443144.GM21_0474	2.725e-92	309.0	COG0398@1|root,COG0398@2|Bacteria,1MVF3@1224|Proteobacteria,42R7A@68525|delta/epsilon subdivisions,2WN7K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_1273935_1	243231.GSU0923	0.0	1109.0	COG0466@1|root,COG0466@2|Bacteria,1R5WH@1224|Proteobacteria,42NIB@68525|delta/epsilon subdivisions,2WJA6@28221|Deltaproteobacteria,43TEJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-1	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_1273935_3	316067.Geob_1227	3.655e-215	676.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42NKZ@68525|delta/epsilon subdivisions,2WIRB@28221|Deltaproteobacteria,43U7T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
REGS1_k127_1273935_0	1121918.ARWE01000001_gene3185	0.0	1746.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJVV@28221|Deltaproteobacteria,43TUU@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	acrB	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
REGS1_k127_1273935_5	243231.GSU2697	1.81e-183	582.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,42NHV@68525|delta/epsilon subdivisions,2WJBA@28221|Deltaproteobacteria,43T2U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	acrA	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
REGS1_k127_1273935_20	338966.Ppro_0332	2.115e-85	286.0	COG1309@1|root,COG1309@2|Bacteria,1N0GT@1224|Proteobacteria,42RFI@68525|delta/epsilon subdivisions,2X5UB@28221|Deltaproteobacteria,43TM3@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Tetracycline repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_10,TetR_N
REGS1_k127_1273935_37	1232410.KI421421_gene3330	1.898e-49	181.0	COG4251@1|root,COG5001@1|root,COG4251@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria	1224|Proteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,PAS_3,PAS_4,PAS_9
REGS1_k127_1273935_48	1121918.ARWE01000001_gene1964	0.0004032	51.0	2DX7M@1|root,343RD@2|Bacteria,1QC6U@1224|Proteobacteria,4320F@68525|delta/epsilon subdivisions,2WWWP@28221|Deltaproteobacteria,43VHZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1273935_8	338966.Ppro_3640	3.7e-148	474.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2WKC5@28221|Deltaproteobacteria,43TVM@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GGDEF,HD,HD_5,dCache_2
REGS1_k127_1273935_29	1313304.CALK_1724	2.257e-64	227.0	COG1136@1|root,COG1136@2|Bacteria	2|Bacteria	V	lipoprotein transporter activity	macB_2	-	-	ko:K02003,ko:K09810	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.125	-	-	ABC_tran
REGS1_k127_1273935_25	118005.AWNK01000006_gene1264	1.811e-70	255.0	COG4591@1|root,COG4591@2|Bacteria	2|Bacteria	M	lipoprotein localization to outer membrane	-	-	-	ko:K02004,ko:K09808	ko02010,map02010	M00255,M00258	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.125	-	-	FtsX,MacB_PCD
REGS1_k127_1273935_35	243231.GSU0793	3.018e-51	186.0	COG4314@1|root,COG4314@2|Bacteria,1RID8@1224|Proteobacteria,42SYX@68525|delta/epsilon subdivisions,2WPEE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
REGS1_k127_1273935_45	1121459.AQXE01000007_gene566	6.42e-19	91.0	COG0840@1|root,COG2703@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,1RBB1@1224|Proteobacteria,42RNA@68525|delta/epsilon subdivisions,2WNGN@28221|Deltaproteobacteria,2MGVG@213115|Desulfovibrionales	28221|Deltaproteobacteria	NPT	PFAM chemotaxis	-	-	-	ko:K03406,ko:K07216	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Hemerythrin,MCPsignal,PilJ
REGS1_k127_1273935_34	330779.Saci_1101	7.078e-52	195.0	COG0801@1|root,arCOG07203@2157|Archaea	2157|Archaea	H	Dihydroneopterin aldolase	-	-	-	-	-	-	-	-	-	-	-	-	FolB,HPPK
REGS1_k127_1273935_26	344747.PM8797T_30022	2.117e-70	245.0	COG1028@1|root,COG1028@2|Bacteria,2IXK3@203682|Planctomycetes	203682|Planctomycetes	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
REGS1_k127_1273935_22	1463900.JOIX01000041_gene1984	6.706e-84	286.0	COG0302@1|root,COG0302@2|Bacteria,2H2JE@201174|Actinobacteria	201174|Actinobacteria	H	GTP cyclohydrolase I	-	-	-	-	-	-	-	-	-	-	-	-	GTP_cyclohydroI
REGS1_k127_1273935_7	697282.Mettu_0616	7.234e-149	486.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
REGS1_k127_1273935_38	1232410.KI421428_gene1181	6.647e-42	156.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,42U1P@68525|delta/epsilon subdivisions,2WQF3@28221|Deltaproteobacteria,43STN@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Pterin 4 alpha carbinolamine dehydratase	phhB	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
REGS1_k127_1273935_14	243231.GSU2435	6.314e-117	389.0	COG0508@1|root,COG0508@2|Bacteria,1MUGY@1224|Proteobacteria,42RDN@68525|delta/epsilon subdivisions,2WMR0@28221|Deltaproteobacteria,43UTA@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	of components of various dehydrogenase complexes	pdhC	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
REGS1_k127_1273935_10	443143.GM18_1973	1.515e-140	449.0	COG0022@1|root,COG0022@2|Bacteria,1R8KB@1224|Proteobacteria,42MBM@68525|delta/epsilon subdivisions,2WJKG@28221|Deltaproteobacteria,43S8T@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Transketolase central region	pdhB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2753	Transket_pyr,Transketolase_C
REGS1_k127_1295116_6	443144.GM21_0285	3.923e-152	483.0	COG0204@1|root,COG0318@1|root,COG0477@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,COG2814@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2WIZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	phospholipid glycerol acyltransferase	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase,MFS_1
REGS1_k127_1295116_9	316067.Geob_2743	2.359e-103	342.0	COG1183@1|root,COG1183@2|Bacteria,1MYK9@1224|Proteobacteria,4305M@68525|delta/epsilon subdivisions,2WVCR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_1295116_0	316067.Geob_0069	0.0	1305.0	28JHJ@1|root,2Z9B3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1295116_13	443143.GM18_1309	5.5e-68	237.0	COG0344@1|root,COG0344@2|Bacteria	2|Bacteria	I	acyl-phosphate glycerol-3-phosphate acyltransferase activity	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
REGS1_k127_1295116_4	443143.GM18_1310	1.179e-209	665.0	COG0075@1|root,COG3916@1|root,COG0075@2|Bacteria,COG3916@2|Bacteria	2|Bacteria	QT	Acyl-homoserine-lactone synthase	-	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AIRS,Acetyltransf_10,Acetyltransf_5,Aminotran_5
REGS1_k127_1295116_2	316067.Geob_0070	5.343e-245	789.0	COG5373@1|root,COG5373@2|Bacteria,1QFJD@1224|Proteobacteria,43499@68525|delta/epsilon subdivisions,2X2KI@28221|Deltaproteobacteria,43VWU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2339
REGS1_k127_1295116_12	269799.Gmet_0085	3.823e-75	260.0	COG2365@1|root,COG2365@2|Bacteria,1N0NB@1224|Proteobacteria,43CF8@68525|delta/epsilon subdivisions,2X60D@28221|Deltaproteobacteria,43UY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Dual specificity phosphatase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase2
REGS1_k127_1295116_3	338966.Ppro_3370	5.557e-240	750.0	COG3863@1|root,COG3863@2|Bacteria,1R3R2@1224|Proteobacteria,42S8G@68525|delta/epsilon subdivisions,2WNZG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
REGS1_k127_1295116_5	903818.KI912268_gene1381	1.222e-178	573.0	COG3863@1|root,COG3863@2|Bacteria	2|Bacteria	T	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
REGS1_k127_1295116_11	653733.Selin_0289	1.458e-83	281.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_1295116_10	1232410.KI421428_gene1000	1.669e-89	312.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2WNTB@28221|Deltaproteobacteria,43U3Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	truC	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
REGS1_k127_1295116_7	269799.Gmet_0270	6.401e-150	481.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aromatic amino acid beta-eliminating lyase threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
REGS1_k127_1295116_1	243231.GSU1103	0.0	998.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ1T@28221|Deltaproteobacteria,43S9K@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
REGS1_k127_1295116_8	398767.Glov_0516	9.404e-116	379.0	29FVD@1|root,302T2@2|Bacteria,1RKWC@1224|Proteobacteria,42TAZ@68525|delta/epsilon subdivisions,2WP8E@28221|Deltaproteobacteria,43T6K@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1295116_14	269799.Gmet_2933	3.659e-19	90.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2WSM2@28221|Deltaproteobacteria,43VNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_1320371_28	1232410.KI421412_gene378	4.556e-13	71.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,42QVP@68525|delta/epsilon subdivisions,2WMT7@28221|Deltaproteobacteria,43TYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Prokaryotic cytochrome b561	cbcB	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_1320371_13	404380.Gbem_0676	2.166e-116	385.0	COG3005@1|root,COG3005@2|Bacteria,1N8UB@1224|Proteobacteria	1224|Proteobacteria	P	Nitrate TMAO reductase, membrane-bound tetraheme cytochrome c subunit	cbcA	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552,Cytochrome_C554,Paired_CXXCH_1
REGS1_k127_1320371_23	443144.GM21_0688	2.828e-35	137.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	2.1.1.80,3.1.1.61,3.1.3.3	ko:K03413,ko:K07315,ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko03021	-	-	-	HATPase_c,HDOD,HD_5,Response_reg
REGS1_k127_1320371_8	1232410.KI421412_gene372	4.29e-182	580.0	COG2204@1|root,COG2204@2|Bacteria,1MVWX@1224|Proteobacteria,42MIB@68525|delta/epsilon subdivisions,2WJQK@28221|Deltaproteobacteria,43TXT@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	ko:K02481	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Sigma54_activat
REGS1_k127_1320371_5	443144.GM21_0685	1.437e-243	775.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria,43SAI@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg
REGS1_k127_1320371_21	316067.Geob_1109	8.313e-42	160.0	COG1502@1|root,COG1502@2|Bacteria	2|Bacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
REGS1_k127_1320371_25	1120999.JONM01000001_gene1205	2.404e-23	104.0	COG3744@1|root,COG3744@2|Bacteria,1RJ4K@1224|Proteobacteria,2VTJR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_1320371_26	1120999.JONM01000001_gene1206	1.313e-16	81.0	COG4118@1|root,COG4118@2|Bacteria,1P66E@1224|Proteobacteria,2W6E0@28216|Betaproteobacteria	28216|Betaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_1320371_29	316067.Geob_3203	4.118e-12	71.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K20374,ko:K21405	ko02024,map02024	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_3
REGS1_k127_1320371_3	404380.Gbem_3570	9.564e-282	870.0	COG0286@1|root,COG0286@2|Bacteria,1MW3A@1224|Proteobacteria,42P6W@68525|delta/epsilon subdivisions,2WM6H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	N-6 DNA methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
REGS1_k127_1320371_16	1305737.JAFX01000001_gene3466	1.291e-70	254.0	COG0732@1|root,COG0732@2|Bacteria,4NK11@976|Bacteroidetes,47QR3@768503|Cytophagia	976|Bacteroidetes	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
REGS1_k127_1320371_0	697282.Mettu_1943	0.0	1201.0	COG4096@1|root,COG4096@2|Bacteria,1QTS7@1224|Proteobacteria,1RN63@1236|Gammaproteobacteria,1XDXX@135618|Methylococcales	1236|Gammaproteobacteria	L	PFAM Restriction endonuclease, type I, EcoEI, R subunit Type III, Res subunit, C-terminal	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
REGS1_k127_1320371_24	665571.STHERM_c17460	7.714e-26	111.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
REGS1_k127_1320371_30	1449126.JQKL01000007_gene660	1.097e-09	64.0	COG1708@1|root,COG1708@2|Bacteria,1VG6Z@1239|Firmicutes,24SA0@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
REGS1_k127_1320371_7	316067.Geob_1108	2.833e-190	599.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
REGS1_k127_1320371_2	316067.Geob_1107	0.0	1116.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,43TCM@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
REGS1_k127_1320371_17	269799.Gmet_3533	1.486e-63	222.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,43UPB@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
REGS1_k127_1320371_10	316067.Geob_1105	1.921e-143	462.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,43TH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
REGS1_k127_1320371_4	316067.Geob_1312	4.187e-279	876.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,43U9D@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
REGS1_k127_1320371_33	1122216.AUHW01000007_gene1473	2.823e-06	52.0	COG1525@1|root,COG1525@2|Bacteria,1VK6A@1239|Firmicutes,4H67V@909932|Negativicutes	909932|Negativicutes	L	nuclease	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding
REGS1_k127_1320371_22	443143.GM18_0150	9.492e-39	154.0	COG0666@1|root,COG0666@2|Bacteria,1PCER@1224|Proteobacteria,438E9@68525|delta/epsilon subdivisions,2WXS2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
REGS1_k127_1320371_31	2340.JV46_24210	1.076e-07	59.0	28PU4@1|root,2ZCF6@2|Bacteria,1N6FV@1224|Proteobacteria,1SZY3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1320371_18	316067.Geob_0027	5.936e-60	210.0	COG1238@1|root,COG1238@2|Bacteria,1RHUV@1224|Proteobacteria,42S81@68525|delta/epsilon subdivisions,2WQCA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM SNARE associated Golgi protein	yqaA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_1320371_9	404380.Gbem_3547	2.664e-150	486.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,43T5K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_1320371_1	316067.Geob_0549	0.0	1142.0	COG3829@1|root,COG4624@1|root,COG3829@2|Bacteria,COG4624@2|Bacteria,1R8T5@1224|Proteobacteria,42Q3W@68525|delta/epsilon subdivisions,2WK6C@28221|Deltaproteobacteria,43TPK@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Domains FehydlgC, FeS, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,HTH_8,Sigma54_activat
REGS1_k127_1320371_6	316067.Geob_0551	5.436e-228	714.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,42M04@68525|delta/epsilon subdivisions,2WJJD@28221|Deltaproteobacteria,43TS3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
REGS1_k127_1320371_19	316067.Geob_0552	1.262e-45	167.0	COG0745@1|root,COG0745@2|Bacteria,1NZKJ@1224|Proteobacteria,430ZP@68525|delta/epsilon subdivisions,2WW45@28221|Deltaproteobacteria,43V78@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	cheY40H-5	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_1320371_14	443143.GM18_1786	4.864e-101	339.0	COG2201@1|root,COG2201@2|Bacteria,1QBTV@1224|Proteobacteria,42Y53@68525|delta/epsilon subdivisions,2WTZV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
REGS1_k127_1320371_12	357808.RoseRS_0036	1.049e-126	430.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,2G6G3@200795|Chloroflexi,374SA@32061|Chloroflexia	32061|Chloroflexia	T	ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
REGS1_k127_1320371_11	316067.Geob_0555	5.431e-141	465.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria,43T5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	mcp40H-17	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,MCPsignal
REGS1_k127_1320371_15	316067.Geob_0555	5.763e-95	314.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria,43T5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	mcp40H-17	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,MCPsignal
REGS1_k127_132463_7	318167.Sfri_1018	2.127e-53	209.0	COG4932@1|root,COG5492@1|root,COG4932@2|Bacteria,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,1RZEW@1236|Gammaproteobacteria,2QASD@267890|Shewanellaceae	1236|Gammaproteobacteria	N	PFAM Ig domain protein group 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566
REGS1_k127_132463_4	316067.Geob_1964	2.809e-177	572.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42N2D@68525|delta/epsilon subdivisions,2WIJV@28221|Deltaproteobacteria,43S99@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF4080)	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
REGS1_k127_132463_8	398767.Glov_2058	2.167e-35	151.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria,1MU3V@1224|Proteobacteria,42NRF@68525|delta/epsilon subdivisions,2WJZ6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Rhodanese domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_132463_1	269799.Gmet_2738	1.682e-306	953.0	COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIWN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
REGS1_k127_132463_5	243231.GSU0877	4.314e-62	221.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,4321Z@68525|delta/epsilon subdivisions,2WWZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,Response_reg
REGS1_k127_132463_3	269799.Gmet_3173	4.091e-186	586.0	COG0075@1|root,COG0075@2|Bacteria,1MWHJ@1224|Proteobacteria,42MBH@68525|delta/epsilon subdivisions,2WJQV@28221|Deltaproteobacteria,43S19@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
REGS1_k127_132463_0	316067.Geob_3686	0.0	1001.0	COG2864@1|root,COG2864@2|Bacteria,1NJEJ@1224|Proteobacteria,42NQM@68525|delta/epsilon subdivisions,2WK76@28221|Deltaproteobacteria,43U5U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c3	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Ni_hydr_CYTB
REGS1_k127_132463_2	269799.Gmet_3174	4.834e-257	799.0	COG3005@1|root,COG3005@2|Bacteria,1R956@1224|Proteobacteria,42Q0X@68525|delta/epsilon subdivisions,2WMHI@28221|Deltaproteobacteria,43U0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
REGS1_k127_132463_12	765913.ThidrDRAFT_4672	5.661e-06	52.0	COG1708@1|root,COG1895@1|root,COG1708@2|Bacteria,COG1895@2|Bacteria,1N8XB@1224|Proteobacteria,1SFUS@1236|Gammaproteobacteria,1WZGT@135613|Chromatiales	135613|Chromatiales	S	DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
REGS1_k127_132463_11	243231.GSU2471	1.538e-19	89.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42RS8@68525|delta/epsilon subdivisions,2WND0@28221|Deltaproteobacteria,43UCV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	Cas_Cas1,GIIM,RVT_1
REGS1_k127_132463_9	322710.Avin_04240	1.487e-25	109.0	COG2944@1|root,COG2944@2|Bacteria,1N5H0@1224|Proteobacteria,1SEZI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31,MqsA_antitoxin
REGS1_k127_132463_6	269799.Gmet_0316	1.795e-53	188.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,42V08@68525|delta/epsilon subdivisions,2WSA8@28221|Deltaproteobacteria,43VMZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
REGS1_k127_1370606_3	404380.Gbem_3051	1.403e-18	89.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,MASE3,PAS,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_1370606_1	338966.Ppro_1879	2.88e-81	283.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WIR4@28221|Deltaproteobacteria,43U9C@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,MASE3,PAS,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_1370606_0	404380.Gbem_3149	6.19e-257	812.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
REGS1_k127_1370606_2	443144.GM21_1111	3.238e-32	128.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,42U7W@68525|delta/epsilon subdivisions,2WQ9A@28221|Deltaproteobacteria,43UXU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Glycerophosphoryl diester phosphodiesterase family	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
REGS1_k127_140051_0	316067.Geob_1124	3.358e-245	760.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
REGS1_k127_140051_1	243231.GSU0152	2.265e-154	492.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,43TZK@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_146491_0	443144.GM21_2511	2.439e-175	559.0	COG4984@1|root,COG4984@2|Bacteria,1RB7Y@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157,DUF4401
REGS1_k127_146491_1	443144.GM21_2510	2.31e-83	293.0	2AT3Q@1|root,31IJS@2|Bacteria,1RIYP@1224|Proteobacteria,42ZYV@68525|delta/epsilon subdivisions,2WVBK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4401)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4401
REGS1_k127_146491_2	443144.GM21_2509	4.91e-67	231.0	COG4929@1|root,COG4929@2|Bacteria,1MZW2@1224|Proteobacteria,42VIB@68525|delta/epsilon subdivisions,2WRZ9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GDYXXLXY protein	-	-	-	-	-	-	-	-	-	-	-	-	GDYXXLXY
REGS1_k127_146491_3	338966.Ppro_1845	2.986e-50	179.0	COG3514@1|root,COG3514@2|Bacteria	2|Bacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
REGS1_k127_1490716_15	1232410.KI421421_gene3354	3.208e-31	124.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,43CAA@68525|delta/epsilon subdivisions,2X7KU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
REGS1_k127_1490716_1	443143.GM18_1256	0.0	1079.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WIK4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH-1	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
REGS1_k127_1490716_2	269799.Gmet_0089	0.0	1049.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43T7Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM UvrD REP helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_1490716_14	592316.Pat9b_2997	2.013e-34	152.0	COG1269@1|root,COG1269@2|Bacteria,1NETU@1224|Proteobacteria,1S1D2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	ATP hydrolysis coupled proton transport	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1490716_12	243231.GSU3383	8.81e-43	158.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,43V4D@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
REGS1_k127_1490716_3	269799.Gmet_0075	6.859e-247	770.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,43TFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
REGS1_k127_1490716_11	1122211.JMLW01000022_gene2540	2.561e-50	180.0	COG4683@1|root,COG4683@2|Bacteria,1MZIY@1224|Proteobacteria,1S686@1236|Gammaproteobacteria,1XKRD@135619|Oceanospirillales	135619|Oceanospirillales	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
REGS1_k127_1490716_13	1122211.JMLW01000022_gene2541	2.868e-38	145.0	COG1396@1|root,COG1396@2|Bacteria,1NN5X@1224|Proteobacteria,1SIT1@1236|Gammaproteobacteria,1XR09@135619|Oceanospirillales	135619|Oceanospirillales	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
REGS1_k127_1490716_0	243231.GSU3325	0.0	1634.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,43U3R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
REGS1_k127_1490716_4	316067.Geob_3810	1.118e-226	709.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_1490716_20	243164.DET1552	0.0001385	46.0	COG1961@1|root,COG1961@2|Bacteria,2G7BH@200795|Chloroflexi,34DMJ@301297|Dehalococcoidia	301297|Dehalococcoidia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
REGS1_k127_1490716_7	316067.Geob_3701	5.462e-120	409.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42S0N@68525|delta/epsilon subdivisions,2WN9X@28221|Deltaproteobacteria,43U96@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA
REGS1_k127_1490716_16	431943.CKL_1537	2.215e-29	136.0	COG2199@1|root,COG3706@2|Bacteria,1VJNQ@1239|Firmicutes,25FV2@186801|Clostridia,36UZC@31979|Clostridiaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Peripla_BP_3
REGS1_k127_1490716_9	243231.GSU0284	5.923e-53	188.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,42RVK@68525|delta/epsilon subdivisions,2WNNA@28221|Deltaproteobacteria,43V2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
REGS1_k127_1490716_5	316067.Geob_3703	9.628e-203	639.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,42MG8@68525|delta/epsilon subdivisions,2WJWP@28221|Deltaproteobacteria,43S0X@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
REGS1_k127_1490716_8	316067.Geob_3704	6.734e-97	336.0	COG1413@1|root,COG1413@2|Bacteria,1NR1B@1224|Proteobacteria,42YUS@68525|delta/epsilon subdivisions,2WUMI@28221|Deltaproteobacteria,43TSX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
REGS1_k127_1490716_6	316067.Geob_3705	2.324e-121	405.0	COG2206@1|root,COG2206@2|Bacteria,1MW7F@1224|Proteobacteria,42PHB@68525|delta/epsilon subdivisions,2WMJX@28221|Deltaproteobacteria,43S0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,KOW
REGS1_k127_1490716_10	316067.Geob_3706	1.938e-51	188.0	COG1413@1|root,COG1413@2|Bacteria,1P4H5@1224|Proteobacteria,42WD8@68525|delta/epsilon subdivisions,2WRJT@28221|Deltaproteobacteria,43UWV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
REGS1_k127_1527656_0	316067.Geob_0336	8.085e-174	560.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,4378Y@68525|delta/epsilon subdivisions,2X2C1@28221|Deltaproteobacteria,43UD2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
REGS1_k127_1527656_4	706587.Desti_1801	7.554e-72	250.0	COG1801@1|root,COG1801@2|Bacteria,1MU7F@1224|Proteobacteria,43BI9@68525|delta/epsilon subdivisions,2X6WN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
REGS1_k127_1527656_2	269799.Gmet_2695	1.275e-155	496.0	COG1052@1|root,COG1052@2|Bacteria,1MU2D@1224|Proteobacteria,42M8N@68525|delta/epsilon subdivisions,2WK7T@28221|Deltaproteobacteria,43SX7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase catalytic region	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
REGS1_k127_1527656_3	269799.Gmet_3424	2.923e-107	349.0	COG1150@1|root,COG1150@2|Bacteria,1N2IK@1224|Proteobacteria,42RP6@68525|delta/epsilon subdivisions,2WQ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	hdrC	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3424	Fer4_17,Fer4_9
REGS1_k127_1527656_1	269799.Gmet_3425	9.438e-158	501.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	heterodisulfide reductase	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
REGS1_k127_1595480_2	1384054.N790_09605	1.668e-89	312.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,1RZRJ@1236|Gammaproteobacteria,1XA50@135614|Xanthomonadales	135614|Xanthomonadales	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	GT87
REGS1_k127_1595480_6	398767.Glov_2674	5.866e-11	74.0	2CF4Z@1|root,330XB@2|Bacteria,1NIZ5@1224|Proteobacteria,42WR5@68525|delta/epsilon subdivisions,2WS24@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
REGS1_k127_1595480_0	443143.GM18_3171	2.022e-135	437.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,42PY0@68525|delta/epsilon subdivisions,2WJ2Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_1595480_1	1121403.AUCV01000005_gene214	7.731e-91	302.0	COG2249@1|root,COG2249@2|Bacteria,1RA5X@1224|Proteobacteria,42R0Z@68525|delta/epsilon subdivisions,2WMNE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NAD(P)H dehydrogenase (quinone)	-	-	1.6.5.2	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	Flavodoxin_2
REGS1_k127_1595480_4	443143.GM18_2037	2.312e-15	76.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,42PAE@68525|delta/epsilon subdivisions,2WMA9@28221|Deltaproteobacteria,43TI8@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
REGS1_k127_1595480_5	1463926.JOCA01000006_gene3963	1.114e-11	69.0	COG0662@1|root,COG0662@2|Bacteria,2INXJ@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_1595480_3	443143.GM18_0500	1.729e-76	265.0	COG0681@1|root,COG0681@2|Bacteria,1RKJ5@1224|Proteobacteria,431MY@68525|delta/epsilon subdivisions,2WX07@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	TIGRFAM signal peptidase I	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
REGS1_k127_1627212_1	269799.Gmet_2949	3.354e-121	395.0	COG2510@1|root,COG2510@2|Bacteria,1QY96@1224|Proteobacteria,43CAZ@68525|delta/epsilon subdivisions,2X7MF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_1627212_4	443143.GM18_3120	2.262e-29	120.0	COG0204@1|root,COG1647@1|root,COG0204@2|Bacteria,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,42NBK@68525|delta/epsilon subdivisions,2WIUP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Acyltransferase,Hydrolase_4
REGS1_k127_1627212_2	335543.Sfum_1335	5.505e-64	230.0	2CIBN@1|root,2Z8JT@2|Bacteria,1QGIJ@1224|Proteobacteria,42S2V@68525|delta/epsilon subdivisions,2WNZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1627212_3	338966.Ppro_1186	2.539e-40	155.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,42VES@68525|delta/epsilon subdivisions,2WRSC@28221|Deltaproteobacteria,43V4J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	nucleic acid phosphodiester bond hydrolysis	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
REGS1_k127_1627212_0	398767.Glov_2228	1.289e-121	392.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,43VVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
REGS1_k127_1694095_3	324925.Ppha_1654	1.067e-185	602.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1FEIU@1090|Chlorobi	2|Bacteria	T	ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg
REGS1_k127_1694095_1	269799.Gmet_2788	2.009e-220	706.0	COG0642@1|root,COG0834@1|root,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43BSB@68525|delta/epsilon subdivisions,2X735@28221|Deltaproteobacteria,43TD7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SBP_bac_3
REGS1_k127_1694095_15	269799.Gmet_2789	1.742e-51	184.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,42T3B@68525|delta/epsilon subdivisions,2WP8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
REGS1_k127_1694095_4	404380.Gbem_2669	3.849e-150	498.0	COG0834@1|root,COG4191@1|root,COG4936@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,PAS_4,PocR,Response_reg,SBP_bac_3
REGS1_k127_1694095_5	443143.GM18_4310	4.955e-149	492.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
REGS1_k127_1694095_7	243231.GSU1891	1.589e-135	440.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,43UAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
REGS1_k127_1694095_10	269799.Gmet_3523	8.865e-104	342.0	COG3155@1|root,COG3155@2|Bacteria,1MW2K@1224|Proteobacteria,42R54@68525|delta/epsilon subdivisions,2WMNZ@28221|Deltaproteobacteria,43U43@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM ThiJ PfpI domain protein	elbB	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
REGS1_k127_1694095_12	269799.Gmet_3438	9.549e-89	296.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1MVQY@1224|Proteobacteria,42REC@68525|delta/epsilon subdivisions,2WNN1@28221|Deltaproteobacteria,43SHP@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
REGS1_k127_1694095_2	243231.GSU0080	7.113e-198	626.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43T3R@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase S1 and S6, chymotrypsin Hap	degQ	-	3.4.21.107	ko:K04771,ko:K04772	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_1694095_17	316067.Geob_1026	6.99e-38	145.0	2CDR8@1|root,32ZSF@2|Bacteria,1NCBG@1224|Proteobacteria,42V4S@68525|delta/epsilon subdivisions,2WSDP@28221|Deltaproteobacteria,43VIE@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1694095_6	269799.Gmet_3435	1.736e-139	449.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,43T73@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_1694095_8	243231.GSU0083	3.586e-111	365.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,43TE9@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
REGS1_k127_1694095_14	316067.Geob_2688	5.02e-57	207.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
REGS1_k127_1694095_18	269799.Gmet_0118	1.987e-28	115.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,42X24@68525|delta/epsilon subdivisions,2WSTX@28221|Deltaproteobacteria,43STB@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
REGS1_k127_1694095_9	269799.Gmet_0120	1.96e-107	353.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,43SDN@69541|Desulfuromonadales	28221|Deltaproteobacteria	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
REGS1_k127_1694095_16	243231.GSU0374	7.671e-44	162.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2WS29@28221|Deltaproteobacteria,43SQV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
REGS1_k127_1694095_19	443143.GM18_3105	1.563e-12	70.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	hybT	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_1694095_13	443143.GM18_3106	2.587e-65	226.0	COG0680@1|root,COG0680@2|Bacteria,1N3AS@1224|Proteobacteria,43AZK@68525|delta/epsilon subdivisions,2WWR2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hybP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
REGS1_k127_1694095_0	404380.Gbem_3136	0.0	1029.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hybL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
REGS1_k127_1694095_11	404380.Gbem_3137	9.525e-96	316.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
REGS1_k127_1783322_8	159087.Daro_2753	2.356e-07	53.0	COG3263@1|root,COG3263@2|Bacteria	2|Bacteria	P	cell volume homeostasis	cvrA	-	-	ko:K03316,ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36,2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
REGS1_k127_1783322_1	1125863.JAFN01000001_gene3386	1.97e-269	839.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42NJZ@68525|delta/epsilon subdivisions,2WK1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
REGS1_k127_1783322_6	207954.MED92_17010	9.298e-27	113.0	COG4327@1|root,COG4327@2|Bacteria,1N0TK@1224|Proteobacteria,1S8V9@1236|Gammaproteobacteria,1XKTS@135619|Oceanospirillales	135619|Oceanospirillales	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
REGS1_k127_1783322_3	316067.Geob_2328	4.102e-78	269.0	COG1414@1|root,COG1414@2|Bacteria,1R66I@1224|Proteobacteria	1224|Proteobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
REGS1_k127_1783322_4	269799.Gmet_0180	6.715e-68	233.0	COG2030@1|root,COG2030@2|Bacteria,1RHPH@1224|Proteobacteria,42T27@68525|delta/epsilon subdivisions,2WPTI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
REGS1_k127_1783322_7	443143.GM18_3965	1.212e-22	100.0	COG2501@1|root,COG2501@2|Bacteria,1Q3UC@1224|Proteobacteria,42XU3@68525|delta/epsilon subdivisions,2WT5S@28221|Deltaproteobacteria,43VY1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM RNA-binding S4 domain protein	-	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
REGS1_k127_1783322_5	443143.GM18_3454	2.233e-29	136.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1783322_2	316067.Geob_3306	7.448e-123	406.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42N0S@68525|delta/epsilon subdivisions,2WM1Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Polynucleotide adenylyltransferase region	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
REGS1_k127_1783322_0	443143.GM18_1319	0.0	4441.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_1842348_0	316067.Geob_0384	0.0	1288.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
REGS1_k127_1842348_1	338966.Ppro_3304	1.144e-75	255.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,42RDZ@68525|delta/epsilon subdivisions,2WQ4Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
REGS1_k127_1842348_2	443144.GM21_0786	5.965e-25	104.0	COG2003@1|root,COG2003@2|Bacteria,1R5NH@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the UPF0758 family	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
REGS1_k127_1860343_5	1220534.B655_1999	9.356e-65	250.0	COG0642@1|root,COG0784@1|root,arCOG02348@1|root,arCOG02352@1|root,arCOG06712@1|root,arCOG02348@2157|Archaea,arCOG02352@2157|Archaea,arCOG02358@2157|Archaea,arCOG06537@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_1860343_7	443144.GM21_2070	6.946e-41	175.0	COG3852@1|root,COG4251@1|root,COG4936@1|root,COG3852@2|Bacteria,COG4251@2|Bacteria,COG4936@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_1860343_2	765911.Thivi_2576	2.774e-191	639.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,1T2RH@1236|Gammaproteobacteria,1WW59@135613|Chromatiales	135613|Chromatiales	NT	PFAM CheB methylesterase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10,PAS_4
REGS1_k127_1860343_9	243231.GSU2812	1.148e-24	108.0	COG0695@1|root,COG0695@2|Bacteria	2|Bacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
REGS1_k127_1860343_4	316067.Geob_1976	3.927e-79	271.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WP90@28221|Deltaproteobacteria,43UQC@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Redoxin	prx-1	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
REGS1_k127_1860343_3	398767.Glov_2275	5.451e-100	331.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,43T44@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
REGS1_k127_1860343_6	316067.Geob_1528	1.147e-55	202.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43UYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_1860343_10	338966.Ppro_2849	2.134e-05	51.0	COG4447@1|root,COG4447@2|Bacteria,1PFCA@1224|Proteobacteria,42WUH@68525|delta/epsilon subdivisions,2WT3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
REGS1_k127_1860343_1	398767.Glov_0642	8.147e-230	736.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
REGS1_k127_1860343_0	316067.Geob_0814	0.0	1515.0	COG1361@1|root,COG1520@1|root,COG1657@1|root,COG4257@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1657@2|Bacteria,COG4257@2|Bacteria,COG4733@2|Bacteria,1QYWJ@1224|Proteobacteria,43CDC@68525|delta/epsilon subdivisions,2X7P6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
REGS1_k127_1860407_3	316067.Geob_0948	2.227e-183	578.0	COG0841@1|root,COG1538@1|root,COG0841@2|Bacteria,COG1538@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43U53@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran,OEP
REGS1_k127_1860407_22	243231.GSU1550	1.985e-32	126.0	COG1942@1|root,COG1942@2|Bacteria,1N6WW@1224|Proteobacteria,42V9V@68525|delta/epsilon subdivisions,2WRUI@28221|Deltaproteobacteria,43VWG@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
REGS1_k127_1860407_19	316067.Geob_2748	2.187e-44	165.0	2E3G3@1|root,32YEY@2|Bacteria,1N87D@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1860407_10	398767.Glov_0171	1.636e-119	389.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,42Q5T@68525|delta/epsilon subdivisions,2WKN4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0173 family	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
REGS1_k127_1860407_5	269799.Gmet_2519	1.568e-142	465.0	COG0845@1|root,COG0845@2|Bacteria,1MX0G@1224|Proteobacteria,42RBE@68525|delta/epsilon subdivisions,2WN7J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_1860407_17	316067.Geob_0950	1.028e-50	187.0	COG1309@1|root,COG1309@2|Bacteria,1NM2A@1224|Proteobacteria,42XG6@68525|delta/epsilon subdivisions,2WT4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_1860407_20	269799.Gmet_0292	7.01e-44	186.0	COG4412@1|root,COG4932@1|root,COG4412@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1860407_23	391603.FBALC1_04702	4.647e-24	121.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,Laminin_G_3,PKD
REGS1_k127_1860407_28	1123073.KB899241_gene2108	1.028e-07	67.0	COG2374@1|root,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	nucH	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Calx-beta,Exo_endo_phos,LTD
REGS1_k127_1860407_27	1499967.BAYZ01000166_gene6627	9.05e-12	80.0	COG3291@1|root,COG4447@1|root,COG3291@2|Bacteria,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko02000	1.B.40.2	GH5,GH9	-	CBM_3,PKD,fn3
REGS1_k127_1860407_7	1121957.ATVL01000014_gene1459	7.531e-136	486.0	COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1860407_24	1535422.ND16A_2150	6.287e-19	104.0	COG3485@1|root,COG4932@1|root,COG5276@1|root,COG3485@2|Bacteria,COG4932@2|Bacteria,COG5276@2|Bacteria,1QUEG@1224|Proteobacteria	1224|Proteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,CarboxypepD_reg,DUF11,FG-GAP
REGS1_k127_1860407_1	483219.LILAB_18585	2.911e-290	936.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	2|Bacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Big_2,CHU_C,RCC1
REGS1_k127_1860407_4	1121918.ARWE01000001_gene3171	6.785e-170	577.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,42W78@68525|delta/epsilon subdivisions,2WRWC@28221|Deltaproteobacteria,43UGB@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	BTAD,GerE
REGS1_k127_1860407_13	316067.Geob_0951	3.011e-84	283.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,43UTY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
REGS1_k127_1860407_6	404380.Gbem_0635	2.452e-141	456.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
REGS1_k127_1860407_9	316067.Geob_0953	2.622e-122	397.0	COG1852@1|root,COG1852@2|Bacteria,1RAI2@1224|Proteobacteria,42QUD@68525|delta/epsilon subdivisions,2WMQ5@28221|Deltaproteobacteria,43STT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF116	-	-	-	ko:K09729	-	-	-	-	ko00000	-	-	-	DUF116
REGS1_k127_1860407_18	269799.Gmet_2947	1.624e-49	183.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,42UMS@68525|delta/epsilon subdivisions,2WQA3@28221|Deltaproteobacteria,43W0P@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Dihydrofolate reductase	folA	-	1.5.1.3	ko:K00287,ko:K18589	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	br01600,ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	DHFR_1
REGS1_k127_1860407_15	243231.GSU0577	2.003e-69	244.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,43UWI@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
REGS1_k127_1860407_21	316067.Geob_1555	5.635e-41	161.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42T19@68525|delta/epsilon subdivisions,2WQ0M@28221|Deltaproteobacteria,43UV0@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
REGS1_k127_1860407_11	316067.Geob_1556	1.733e-110	368.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42TT7@68525|delta/epsilon subdivisions,2WQR1@28221|Deltaproteobacteria,43TI3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
REGS1_k127_1860407_8	269799.Gmet_0890	1.63e-127	417.0	COG0758@1|root,COG1948@1|root,COG0758@2|Bacteria,COG1948@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,43U42@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
REGS1_k127_1860407_0	269799.Gmet_0891	0.0	1270.0	COG0550@1|root,COG0550@2|Bacteria,1MUFZ@1224|Proteobacteria,42MM9@68525|delta/epsilon subdivisions,2WJTT@28221|Deltaproteobacteria,43UAK@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
REGS1_k127_1860407_2	269799.Gmet_0893	1.698e-218	685.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,42MTS@68525|delta/epsilon subdivisions,2WJ50@28221|Deltaproteobacteria,43T6Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
REGS1_k127_1860407_16	316067.Geob_1563	1.491e-68	239.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,43UWG@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Maf family protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
REGS1_k127_1860407_29	575586.HMPREF0016_02280	0.0003226	51.0	COG1305@1|root,COG1305@2|Bacteria,1MW3P@1224|Proteobacteria,1RSQ5@1236|Gammaproteobacteria,3NMKI@468|Moraxellaceae	1236|Gammaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
REGS1_k127_1860407_12	269799.Gmet_0896	4.387e-100	330.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,43TVQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
REGS1_k127_1860407_14	105559.Nwat_0162	7.62e-82	282.0	COG0457@1|root,COG0457@2|Bacteria,1QW2Y@1224|Proteobacteria,1SGM5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
REGS1_k127_1860585_28	1348583.ATLH01000001_gene3762	7.225e-05	51.0	COG1305@1|root,COG1305@2|Bacteria,4NF37@976|Bacteroidetes,1IIST@117743|Flavobacteriia	976|Bacteroidetes	E	Protein of unknown function (DUF2569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569,DUF3857,Transglut_core
REGS1_k127_1860585_25	1127673.GLIP_3597	5.873e-20	95.0	COG2319@1|root,COG2319@2|Bacteria,1NVWH@1224|Proteobacteria,1SPN1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Wd-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1860585_5	330214.NIDE0660	3.02e-151	486.0	COG1373@1|root,COG1373@2|Bacteria,3J14P@40117|Nitrospirae	40117|Nitrospirae	S	AAA domain	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
REGS1_k127_1860585_24	269799.Gmet_3646	5.799e-22	95.0	29ATH@1|root,2ZXSZ@2|Bacteria,1P51I@1224|Proteobacteria,433KB@68525|delta/epsilon subdivisions,2WXR7@28221|Deltaproteobacteria,43VUD@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1860585_0	443143.GM18_4305	2.4e-247	773.0	COG0348@1|root,COG1143@1|root,COG1245@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,COG1245@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
REGS1_k127_1860585_8	338966.Ppro_3320	1.252e-114	375.0	COG1237@1|root,COG1237@2|Bacteria,1NK2I@1224|Proteobacteria,42QRA@68525|delta/epsilon subdivisions,2WN1V@28221|Deltaproteobacteria,43UE5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
REGS1_k127_1860585_21	243231.GSU0396	1.962e-29	119.0	COG0607@1|root,32YCZ@2|Bacteria,1N6NN@1224|Proteobacteria,42XFU@68525|delta/epsilon subdivisions,2WSTK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
REGS1_k127_1860585_7	443143.GM18_3545	2.325e-132	430.0	COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,1N3KK@1224|Proteobacteria,42TH7@68525|delta/epsilon subdivisions,2WQ6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Uncharacterized protein conserved in bacteria (DUF2087)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2087,GIY-YIG,HTH_20
REGS1_k127_1860585_23	398767.Glov_0137	4.192e-23	104.0	COG4753@1|root,COG4753@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko03021	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Pkinase,Response_reg,SpoIIE
REGS1_k127_1860585_22	269799.Gmet_2956	4.353e-27	114.0	COG2202@1|root,COG2203@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2WPBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,NMT1,PAS_4,PAS_9,PocR,SBP_bac_3,dCache_1
REGS1_k127_1860585_1	316067.Geob_0371	7.792e-207	653.0	COG4277@1|root,COG4277@2|Bacteria,1MVCV@1224|Proteobacteria,42NNA@68525|delta/epsilon subdivisions,2WTR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
REGS1_k127_1860585_10	316067.Geob_0372	1.976e-99	331.0	2A3KK@1|root,30S3R@2|Bacteria,1QYD5@1224|Proteobacteria,42UKR@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Domain of unknown function (DUF4130	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
REGS1_k127_1860585_12	316067.Geob_0072	1.888e-91	340.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
REGS1_k127_1860585_26	398767.Glov_1458	6.512e-18	100.0	COG3055@1|root,COG4412@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4412@2|Bacteria,COG4447@2|Bacteria,1MWWV@1224|Proteobacteria,42S3D@68525|delta/epsilon subdivisions,2WNYK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Large extracellular alpha-helical protein	-	-	-	ko:K09607	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_C13
REGS1_k127_1860585_3	243231.GSU2462	4.476e-202	632.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,42N1M@68525|delta/epsilon subdivisions,2WJRJ@28221|Deltaproteobacteria,43SYJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metXA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Homoserine_dh,NAD_binding_3
REGS1_k127_1860585_20	1305737.JAFX01000001_gene2224	2.961e-30	129.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,47R93@768503|Cytophagia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
REGS1_k127_1860585_4	269799.Gmet_2607	3.779e-154	489.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,42MVM@68525|delta/epsilon subdivisions,2WUFN@28221|Deltaproteobacteria,43TXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
REGS1_k127_1860585_27	269799.Gmet_0243	5.278e-12	79.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
REGS1_k127_1860585_16	443144.GM21_3859	4.946e-59	209.0	COG1576@1|root,COG1576@2|Bacteria,1N7WB@1224|Proteobacteria,42V41@68525|delta/epsilon subdivisions,2X6IT@28221|Deltaproteobacteria,43UX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
REGS1_k127_1860585_19	443143.GM18_4208	1.238e-42	162.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,43V3J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
REGS1_k127_1860585_13	269799.Gmet_3200	8.636e-79	269.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,43TVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
REGS1_k127_1860585_2	243231.GSU3211	1.746e-202	638.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,43U79@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_1860585_17	316067.Geob_1412	2.406e-55	201.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,42TQG@68525|delta/epsilon subdivisions,2WQG8@28221|Deltaproteobacteria,43UXD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
REGS1_k127_1860585_14	243231.GSU3157	2.039e-75	261.0	COG2267@1|root,COG2267@2|Bacteria,1MX0N@1224|Proteobacteria,42P9B@68525|delta/epsilon subdivisions,2WMCP@28221|Deltaproteobacteria,43UCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
REGS1_k127_1860585_11	269799.Gmet_0774	3.766e-94	311.0	COG0288@1|root,COG0288@2|Bacteria,1R3SC@1224|Proteobacteria,42VNU@68525|delta/epsilon subdivisions,2WRX5@28221|Deltaproteobacteria,43U3V@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Reversible hydration of carbon dioxide	-	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
REGS1_k127_1860585_18	443143.GM18_2679	2.106e-44	167.0	COG0727@1|root,COG0727@2|Bacteria,1N3UP@1224|Proteobacteria,42U10@68525|delta/epsilon subdivisions,2WQ8S@28221|Deltaproteobacteria,43V2K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
REGS1_k127_1860585_6	443144.GM21_3477	5.238e-142	457.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,43SCB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90	ko:K02523,ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061,R09248	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_1860585_15	443143.GM18_0688	1.022e-68	237.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,43UYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	Thioredoxin-like	resA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_1860585_9	243231.GSU1322	1.879e-101	334.0	COG0785@1|root,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,43T44@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c biogenesis protein, transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
REGS1_k127_1860695_2	243231.GSU2599	3.673e-176	560.0	COG3547@1|root,COG3547@2|Bacteria,1NGR7@1224|Proteobacteria,42NNQ@68525|delta/epsilon subdivisions,2WM2H@28221|Deltaproteobacteria,43TYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_1860695_7	118173.KB235914_gene3364	4.214e-72	247.0	COG4974@1|root,COG4974@2|Bacteria,1G224@1117|Cyanobacteria,1H8SW@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
REGS1_k127_1860695_5	443143.GM18_2818	1.141e-128	422.0	COG0457@1|root,COG0457@2|Bacteria	443143.GM18_2818|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1860695_4	316067.Geob_3275	1.495e-131	423.0	COG0070@1|root,COG0070@2|Bacteria,1QUKN@1224|Proteobacteria,42R9Q@68525|delta/epsilon subdivisions,2WMN0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM glutamate synthase alpha subunit	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1752	GXGXG
REGS1_k127_1860695_0	269799.Gmet_1753	1.761e-214	669.0	COG0067@1|root,COG0067@2|Bacteria,1QUKP@1224|Proteobacteria,42Q1T@68525|delta/epsilon subdivisions,2WMJE@28221|Deltaproteobacteria,43SSD@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Glutamine amidotransferases class-II	-	-	-	-	-	-	-	-	-	-	-	-	GATase_2,GATase_6
REGS1_k127_1860695_1	243231.GSU1237	2.433e-203	639.0	COG1251@1|root,COG1251@2|Bacteria,1MW58@1224|Proteobacteria,42PSQ@68525|delta/epsilon subdivisions,2WKDY@28221|Deltaproteobacteria,43UUR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_1860695_6	316067.Geob_3278	4.007e-80	268.0	COG1142@1|root,COG1142@2|Bacteria,1N3SY@1224|Proteobacteria,42TSW@68525|delta/epsilon subdivisions,2WQB9@28221|Deltaproteobacteria,43VEB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00196,ko:K05796	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001	-	-	iAF987.Gmet_1755	Fer4_11,Fer4_7
REGS1_k127_1860695_3	316067.Geob_3279	6.942e-166	522.0	COG0069@1|root,COG0069@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the glutamate synthase family	-	-	2.1.1.21	ko:K22083	ko00680,ko01120,map00680,map01120	-	R01586	RC00554	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_10,Fer4_7,Fer4_9,GXGXG,Glu_syn_central,Glu_synthase
REGS1_k127_1860939_9	1121930.AQXG01000003_gene2693	1.194e-45	172.0	2BUWD@1|root,3112X@2|Bacteria,4NRC2@976|Bacteroidetes	976|Bacteroidetes	S	SatD family (SatD)	-	-	-	-	-	-	-	-	-	-	-	-	SatD
REGS1_k127_1860939_13	1121104.AQXH01000001_gene1271	3.414e-15	79.0	2EGYX@1|root,33AR1@2|Bacteria,4NZA4@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1860939_11	1173264.KI913949_gene25	1.922e-34	147.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G1QI@1117|Cyanobacteria,1H7BP@1150|Oscillatoriales	1117|Cyanobacteria	NU	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_10,TPR_12,TPR_7,TPR_8
REGS1_k127_1860939_14	338966.Ppro_2183	1.281e-14	86.0	2EMFB@1|root,33F44@2|Bacteria,1NH7D@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2059
REGS1_k127_1860939_12	426114.THI_3236	2.252e-19	95.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2VM3A@28216|Betaproteobacteria,1KM3X@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
REGS1_k127_1860939_10	338966.Ppro_3744	2.326e-45	172.0	COG1525@1|root,COG1525@2|Bacteria,1N145@1224|Proteobacteria,42SG5@68525|delta/epsilon subdivisions,2WNPI@28221|Deltaproteobacteria,43UXJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	Ada_Zn_binding,Excalibur,SNase
REGS1_k127_1860939_8	713587.THITH_04115	1.056e-55	204.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria,1RRKY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
REGS1_k127_1860939_0	316067.Geob_1151	2.394e-310	956.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,42MYA@68525|delta/epsilon subdivisions,2WKFB@28221|Deltaproteobacteria,43S8M@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	EF-hand_7,Pyridoxal_deC
REGS1_k127_1860939_6	338966.Ppro_0545	2.716e-69	240.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,42QRY@68525|delta/epsilon subdivisions,2WMW2@28221|Deltaproteobacteria,43T1B@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
REGS1_k127_1860939_15	877455.Metbo_0449	6.208e-08	62.0	COG0727@1|root,arCOG02579@2157|Archaea	2157|Archaea	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
REGS1_k127_1860939_2	316067.Geob_1143	2.21e-257	797.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42YJ3@68525|delta/epsilon subdivisions,2WUQQ@28221|Deltaproteobacteria,43SUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
REGS1_k127_1860939_4	316067.Geob_1154	4.146e-194	613.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42PMA@68525|delta/epsilon subdivisions,2X5AR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Major facilitator superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
REGS1_k127_1860939_7	398767.Glov_3017	9.36e-64	224.0	COG0782@1|root,COG0782@2|Bacteria,1MZNI@1224|Proteobacteria,42VKP@68525|delta/epsilon subdivisions,2WSC9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Transcription elongation factor, GreA/GreB, C-term	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB
REGS1_k127_1860939_5	243231.GSU0171	8.419e-76	257.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,42SI7@68525|delta/epsilon subdivisions,2WPSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
REGS1_k127_1860939_3	404380.Gbem_1224	4.378e-202	638.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
REGS1_k127_1860939_1	398767.Glov_3040	6.298e-265	818.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42NH6@68525|delta/epsilon subdivisions,2WJCV@28221|Deltaproteobacteria,43TJT@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_1864954_1	243231.GSU0084	3.603e-105	347.0	COG0436@1|root,COG0436@2|Bacteria,1MUHD@1224|Proteobacteria,43AII@68525|delta/epsilon subdivisions,2X5YR@28221|Deltaproteobacteria,43TWD@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
REGS1_k127_1864954_0	269799.Gmet_3235	1.777e-238	745.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,43U2R@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
REGS1_k127_1903408_1	243231.GSU1326	0.0	1052.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,42NF8@68525|delta/epsilon subdivisions,2WKBA@28221|Deltaproteobacteria,43TAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
REGS1_k127_1903408_12	880072.Desac_1513	1.086e-76	266.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,42PTI@68525|delta/epsilon subdivisions,2WIWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
REGS1_k127_1903408_14	443143.GM18_1948	2.471e-58	213.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,T2SSE_N
REGS1_k127_1903408_5	316067.Geob_3736	1.599e-166	529.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,43UZT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT
REGS1_k127_1903408_11	316067.Geob_3737	1.569e-89	300.0	COG3809@1|root,COG3809@2|Bacteria,1P0JI@1224|Proteobacteria,432XD@68525|delta/epsilon subdivisions,2WY3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
REGS1_k127_1903408_18	316067.Geob_3136	5.531e-27	112.0	COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,42XFV@68525|delta/epsilon subdivisions,2X2GV@28221|Deltaproteobacteria,43VDC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
REGS1_k127_1903408_9	269799.Gmet_1369	4.472e-109	357.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,42S9X@68525|delta/epsilon subdivisions,2WNTZ@28221|Deltaproteobacteria,43SI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_1903408_3	316067.Geob_2180	1.845e-177	561.0	COG1363@1|root,COG1363@2|Bacteria,1MXEU@1224|Proteobacteria,42P13@68525|delta/epsilon subdivisions,2WMM6@28221|Deltaproteobacteria,43TD3@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	peptidase M42 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
REGS1_k127_1903408_15	269799.Gmet_1816	1.44e-56	200.0	COG0760@1|root,COG0760@2|Bacteria,1QQW0@1224|Proteobacteria,42ZWH@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
REGS1_k127_1903408_21	443143.GM18_3588	5.871e-19	93.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
REGS1_k127_1903408_4	316067.Geob_2178	4.074e-168	539.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,43T2G@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_1903408_17	398767.Glov_2108	9.062e-30	120.0	COG0268@1|root,COG0268@2|Bacteria,1NITA@1224|Proteobacteria,42V4U@68525|delta/epsilon subdivisions,2WR9I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
REGS1_k127_1903408_10	316067.Geob_2173	6.587e-102	341.0	COG1466@1|root,COG1466@2|Bacteria,1RHE9@1224|Proteobacteria,42SNR@68525|delta/epsilon subdivisions,2WP96@28221|Deltaproteobacteria,43TIV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
REGS1_k127_1903408_0	269799.Gmet_2300	0.0	1400.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,43TD1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	leucyl-tRNA aminoacylation	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_2300	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
REGS1_k127_1903408_2	316067.Geob_2170	2.742e-316	984.0	COG0484@1|root,COG0484@2|Bacteria,1QXP1@1224|Proteobacteria,43C4V@68525|delta/epsilon subdivisions,2X7F8@28221|Deltaproteobacteria,43W46@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_1903408_13	443144.GM21_0765	1.88e-60	211.0	COG2199@1|root,COG3706@2|Bacteria,1MZZV@1224|Proteobacteria,42UXH@68525|delta/epsilon subdivisions,2WVP3@28221|Deltaproteobacteria,43SMM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	cheY40H-4	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
REGS1_k127_1903408_8	316067.Geob_2168	2.119e-112	368.0	COG2203@1|root,COG2203@2|Bacteria,1RJ35@1224|Proteobacteria,42T0K@68525|delta/epsilon subdivisions,2WPIM@28221|Deltaproteobacteria,43T60@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3
REGS1_k127_1903408_6	316067.Geob_2167	4.74e-132	432.0	COG2201@1|root,COG2201@2|Bacteria,1R5IM@1224|Proteobacteria,42Q4X@68525|delta/epsilon subdivisions,2WMDB@28221|Deltaproteobacteria,43T38@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB40H-1	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
REGS1_k127_1903408_7	316067.Geob_2166	2.278e-127	412.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,43UG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
REGS1_k127_1903408_16	243231.GSU2216	1.617e-31	131.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,43UH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
REGS1_k127_2080165_1	316067.Geob_0022	2.839e-316	987.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2X5K8@28221|Deltaproteobacteria,43TJJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
REGS1_k127_2080165_4	269799.Gmet_0350	1.218e-173	556.0	COG0642@1|root,COG2197@1|root,COG2197@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42RWK@68525|delta/epsilon subdivisions,2WNCS@28221|Deltaproteobacteria,43SHW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, HisKA, HATPase_c	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
REGS1_k127_2080165_3	269799.Gmet_0346	4.375e-178	563.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,43TAM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM DAHP synthetase I KDSA	aroG-2	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
REGS1_k127_2080165_6	404380.Gbem_3815	4.505e-92	305.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2WMK3@28221|Deltaproteobacteria,43UNE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
REGS1_k127_2080165_7	316067.Geob_0614	1.096e-89	301.0	COG1139@1|root,COG1139@2|Bacteria,1RIJX@1224|Proteobacteria,42PGB@68525|delta/epsilon subdivisions,2WK1F@28221|Deltaproteobacteria,43V93@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pfam:DUF162	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
REGS1_k127_2080165_8	316067.Geob_0615	1.037e-83	285.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,43UT3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Phosphoribosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
REGS1_k127_2080165_2	269799.Gmet_0861	1.829e-222	707.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,T2SSE,T2SSE_N
REGS1_k127_2080165_12	1408303.JNJJ01000033_gene2512	2.284e-10	66.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,4HINR@91061|Bacilli,1ZGYC@1386|Bacillus	91061|Bacilli	T	Belongs to the anti-sigma-factor antagonist family	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
REGS1_k127_2080165_13	395493.BegalDRAFT_0543	4.741e-05	51.0	COG2172@1|root,COG2172@2|Bacteria,1N9RD@1224|Proteobacteria,1SH8N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
REGS1_k127_2080165_9	1430440.MGMSRv2_1618	7.798e-51	195.0	COG2199@1|root,COG2208@1|root,COG2208@2|Bacteria,COG3706@2|Bacteria,1MXJQ@1224|Proteobacteria,2U8P3@28211|Alphaproteobacteria,2JSPV@204441|Rhodospirillales	204441|Rhodospirillales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
REGS1_k127_2080165_5	156889.Mmc1_2394	6.87e-160	553.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0834@1|root,COG2198@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3
REGS1_k127_2080165_0	269799.Gmet_3167	0.0	1061.0	COG1199@1|root,COG2003@1|root,COG1199@2|Bacteria,COG2003@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria,43U02@69541|Desulfuromonadales	28221|Deltaproteobacteria	KL	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,RadC,ResIII
REGS1_k127_2080442_6	589865.DaAHT2_1362	3.126e-60	213.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42RAK@68525|delta/epsilon subdivisions,2WJRA@28221|Deltaproteobacteria,2MKMD@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3365,HATPase_c,HisKA
REGS1_k127_2080442_7	589865.DaAHT2_1363	1.18e-49	180.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42T9C@68525|delta/epsilon subdivisions,2WP3Z@28221|Deltaproteobacteria,2MKTX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_2080442_3	653733.Selin_0067	3.847e-148	490.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K21088	ko02026,map02026	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF,dCache_2,dCache_3
REGS1_k127_2080442_4	880073.Calab_0173	3.297e-88	297.0	COG0551@1|root,COG0551@2|Bacteria,2NQZQ@2323|unclassified Bacteria	2|Bacteria	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
REGS1_k127_2080442_1	484770.UFO1_1859	4.442e-215	675.0	COG2704@1|root,COG2704@2|Bacteria,1TR0A@1239|Firmicutes,4H1XY@909932|Negativicutes	909932|Negativicutes	S	Anaerobic c4-dicarboxylate	dcuB	-	-	ko:K07792	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.13.1	-	-	DcuA_DcuB
REGS1_k127_2080442_0	404380.Gbem_2923	4.39e-264	827.0	COG0834@1|root,COG4191@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZV@68525|delta/epsilon subdivisions,2WMI3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Extracellular solute-binding protein, family 3	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SBP_bac_3
REGS1_k127_2080442_2	243231.GSU2753	4.043e-174	555.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42NMK@68525|delta/epsilon subdivisions,2WK6K@28221|Deltaproteobacteria,43TWQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_2130529_19	585199.HMPREF0577_1069	2.068e-05	48.0	COG3077@1|root,COG3077@2|Bacteria,2GRIH@201174|Actinobacteria,4D6NF@85005|Actinomycetales	201174|Actinobacteria	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
REGS1_k127_2130529_18	28072.Nos7524_0704	2.069e-13	83.0	COG0457@1|root,COG0457@2|Bacteria,1GGZJ@1117|Cyanobacteria	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2130529_7	338969.Rfer_3394	3.76e-99	332.0	COG3115@1|root,COG3115@2|Bacteria,1QWGJ@1224|Proteobacteria,2WGZ3@28216|Betaproteobacteria,4AH94@80864|Comamonadaceae	28216|Betaproteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2130529_9	696747.NIES39_C05180	2.114e-85	316.0	COG1520@1|root,COG2931@1|root,COG1520@2|Bacteria,COG2931@2|Bacteria,1GQUQ@1117|Cyanobacteria,1HBB3@1150|Oscillatoriales	1117|Cyanobacteria	G	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347,HemolysinCabind
REGS1_k127_2130529_3	1121094.KB894644_gene2241	3.57e-144	469.0	COG0688@1|root,COG0688@2|Bacteria,4NR69@976|Bacteroidetes,2FVV1@200643|Bacteroidia	976|Bacteroidetes	I	Phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PSDC,PS_Dcarbxylase
REGS1_k127_2130529_13	443143.GM18_3490	1.637e-42	160.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42TNB@68525|delta/epsilon subdivisions,2WQIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Peptidyl-prolyl cis-trans	fbp	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_2130529_14	76114.ebD26	5.717e-41	157.0	COG2020@1|root,COG2020@2|Bacteria,1QVIW@1224|Proteobacteria,2VX8F@28216|Betaproteobacteria	28216|Betaproteobacteria	O	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_2130529_16	1125863.JAFN01000001_gene266	9.017e-29	128.0	COG3043@1|root,COG3043@2|Bacteria,1P0M5@1224|Proteobacteria,431MK@68525|delta/epsilon subdivisions,2WWRX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	anaerobic respiration	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2130529_12	580332.Slit_2333	9.813e-51	183.0	COG3324@1|root,COG3324@2|Bacteria,1N7Q5@1224|Proteobacteria,2VT7E@28216|Betaproteobacteria,44WIN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
REGS1_k127_2130529_1	443143.GM18_3474	6.786e-250	777.0	COG0535@1|root,COG0535@2|Bacteria,1QWQ6@1224|Proteobacteria,43BV0@68525|delta/epsilon subdivisions,2X75Z@28221|Deltaproteobacteria,43U71@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_2130529_2	443143.GM18_3958	2.135e-173	555.0	COG3177@1|root,COG3177@2|Bacteria,1MXWY@1224|Proteobacteria,42RRC@68525|delta/epsilon subdivisions,2WNW3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
REGS1_k127_2130529_11	316067.Geob_0026	1.969e-67	238.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3D@68525|delta/epsilon subdivisions,2WVDQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2130529_0	316067.Geob_3587	4.679e-300	928.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_2130529_4	443143.GM18_3901	3.58e-135	440.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42M2V@68525|delta/epsilon subdivisions,2WKEB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNA methylase	-	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
REGS1_k127_2130529_5	269799.Gmet_0399	4.261e-129	422.0	COG0327@1|root,COG0327@2|Bacteria,1R34P@1224|Proteobacteria,42P4V@68525|delta/epsilon subdivisions,2X6FS@28221|Deltaproteobacteria,43U23@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the GTP cyclohydrolase I type 2 NIF3 family	yqfO	-	-	-	-	-	-	-	-	-	-	-	NIF3
REGS1_k127_2130529_10	443143.GM18_3899	2.913e-74	256.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,43UXQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
REGS1_k127_2130529_17	1279017.AQYJ01000024_gene1077	6.656e-14	78.0	2E9J1@1|root,333RY@2|Bacteria,1NIX0@1224|Proteobacteria,1SGM0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2159998_5	443143.GM18_2827	2.792e-120	389.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42QGW@68525|delta/epsilon subdivisions,2WMEZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C552
REGS1_k127_2159998_2	316067.Geob_2177	1.576e-234	733.0	2C99Z@1|root,2Z9YV@2|Bacteria,1N0B7@1224|Proteobacteria,42P3M@68525|delta/epsilon subdivisions,2WN6Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3373)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3373
REGS1_k127_2159998_12	404380.Gbem_0759	1.241e-43	161.0	2E66J@1|root,330V5@2|Bacteria,1NEPZ@1224|Proteobacteria,430IP@68525|delta/epsilon subdivisions,2WVNS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2159998_1	443143.GM18_3592	1.183e-246	767.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,43T4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
REGS1_k127_2159998_22	644282.Deba_0813	8.318e-09	59.0	COG2331@1|root,COG2331@2|Bacteria,1NGC1@1224|Proteobacteria,42W5D@68525|delta/epsilon subdivisions,2WRAY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM regulatory protein, FmdB	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
REGS1_k127_2159998_6	269799.Gmet_0515	5.593e-96	318.0	COG0053@1|root,COG0053@2|Bacteria,1ND3V@1224|Proteobacteria,431R3@68525|delta/epsilon subdivisions,2WWYS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
REGS1_k127_2159998_20	443144.GM21_0424	1.052e-26	112.0	2EIMJ@1|root,33CCU@2|Bacteria,1NMXZ@1224|Proteobacteria,433IY@68525|delta/epsilon subdivisions,2WY9B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2159998_8	269799.Gmet_2970	3.712e-81	276.0	COG2227@1|root,COG2227@2|Bacteria,1QXN3@1224|Proteobacteria,43C46@68525|delta/epsilon subdivisions,2X7EM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_2159998_11	243231.GSU0382	2.433e-52	187.0	COG1765@1|root,COG1765@2|Bacteria,1QF2H@1224|Proteobacteria,42VZN@68525|delta/epsilon subdivisions,2WSEZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	OsmC
REGS1_k127_2159998_10	118166.JH976537_gene4652	7.69e-64	224.0	COG0500@1|root,COG0500@2|Bacteria,1G4ZC@1117|Cyanobacteria,1HHWQ@1150|Oscillatoriales	1117|Cyanobacteria	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_2159998_13	443143.GM18_2188	1.199e-38	145.0	COG2214@1|root,COG2214@2|Bacteria,1QXNV@1224|Proteobacteria,43E9K@68525|delta/epsilon subdivisions,2X7QZ@28221|Deltaproteobacteria,43W26@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
REGS1_k127_2159998_4	398767.Glov_1191	1.313e-137	443.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WKKK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM cation diffusion facilitator family transporter	dmeF	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
REGS1_k127_2159998_0	316067.Geob_1352	0.0	1782.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,42MI4@68525|delta/epsilon subdivisions,2WKB9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K08357	ko00920,ko01120,ko02020,map00920,map01120,map02020	-	R10150	RC03109	ko00000,ko00001,ko02000	5.A.3.10	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
REGS1_k127_2159998_7	1487923.DP73_01295	1.1e-83	284.0	COG0437@1|root,COG0437@2|Bacteria,1TT2E@1239|Firmicutes,24FTX@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
REGS1_k127_2159998_15	443143.GM18_2396	3.461e-36	139.0	2DRRJ@1|root,33CRQ@2|Bacteria	2|Bacteria	S	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_2159998_16	338966.Ppro_0863	6.095e-36	139.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42VSP@68525|delta/epsilon subdivisions,2WRGT@28221|Deltaproteobacteria,43VD5@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
REGS1_k127_2159998_3	519989.ECTPHS_07212	3.302e-213	677.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,1RRFQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Arsenical pump-driving ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase,CbiA
REGS1_k127_2159998_19	1536770.R50345_16070	5.699e-28	118.0	2DMHQ@1|root,32RMG@2|Bacteria,1VB95@1239|Firmicutes,4HKKS@91061|Bacilli,26XJZ@186822|Paenibacillaceae	91061|Bacilli	S	Arsenic resistance operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	ArsD
REGS1_k127_2159998_9	398767.Glov_1180	1.377e-64	222.0	COG1148@1|root,COG1148@2|Bacteria	2|Bacteria	C	4fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7,FlpD,LdpA_C,Pyr_redox_2
REGS1_k127_2159998_17	398767.Glov_1181	1.029e-33	132.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	fdxB	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,Fer4_6,Fer4_7
REGS1_k127_2180501_16	1123073.KB899241_gene2109	2.407e-07	64.0	COG1879@1|root,COG2374@1|root,COG1879@2|Bacteria,COG2374@2|Bacteria,1MX52@1224|Proteobacteria,1RRGN@1236|Gammaproteobacteria,1X3H2@135614|Xanthomonadales	135614|Xanthomonadales	Q	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,LTD
REGS1_k127_2180501_6	243231.GSU0894	9.88e-83	277.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,42RI1@68525|delta/epsilon subdivisions,2WNBG@28221|Deltaproteobacteria,43UG5@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
REGS1_k127_2180501_4	243231.GSU0895	4.543e-144	481.0	COG2199@1|root,COG2203@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,COG4936@2|Bacteria,1MZV7@1224|Proteobacteria,43AIQ@68525|delta/epsilon subdivisions,2X5YZ@28221|Deltaproteobacteria,43W31@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,PocR
REGS1_k127_2180501_1	243231.GSU0896	1.726e-189	602.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,42QCV@68525|delta/epsilon subdivisions,2WJP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_2180501_3	269799.Gmet_0882	3.97e-146	469.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,42RRH@68525|delta/epsilon subdivisions,2WNID@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	arnD	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0882	Polysacc_deac_1
REGS1_k127_2180501_0	316067.Geob_3547	4.915e-236	738.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
REGS1_k127_2180501_8	398767.Glov_3611	3.207e-73	248.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,43UWR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
REGS1_k127_2180501_9	1117647.M5M_17285	4.706e-58	214.0	COG0517@1|root,COG2199@1|root,COG0517@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,1RMA9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	2.7.7.65	ko:K11444	ko02020,ko02025,map02020,map02025	M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg,dCache_1
REGS1_k127_2180501_12	385682.AFSL01000040_gene218	5.586e-19	92.0	COG2703@1|root,COG2703@2|Bacteria,4PHJ8@976|Bacteroidetes,2G1HE@200643|Bacteroidia,3XKV9@558415|Marinilabiliaceae	976|Bacteroidetes	P	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
REGS1_k127_2180501_2	443143.GM18_1489	4.679e-161	511.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,43S1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM PfkB domain protein	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
REGS1_k127_2180501_5	269799.Gmet_2838	1.916e-99	336.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,43B0E@68525|delta/epsilon subdivisions,2X6EG@28221|Deltaproteobacteria,43U7H@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
REGS1_k127_2180501_7	709032.Sulku_0836	1.437e-74	273.0	COG2202@1|root,COG2203@1|root,COG3452@1|root,COG5001@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3452@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2YMHP@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	signal transduction protein containing a membrane domain an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GGDEF,PAS_4,PAS_9
REGS1_k127_2180501_10	572265.HDEF_p0051	5.797e-30	121.0	COG2929@1|root,COG2929@2|Bacteria,1N83Z@1224|Proteobacteria,1SEV2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	protein conserved in bacteria	Z012_04510	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
REGS1_k127_2180501_13	338966.Ppro_1845	5.651e-18	87.0	COG3514@1|root,COG3514@2|Bacteria	2|Bacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
REGS1_k127_2180501_17	525909.Afer_1753	4.795e-06	54.0	COG1310@1|root,COG1310@2|Bacteria,2HG96@201174|Actinobacteria,4CN7H@84992|Acidimicrobiia	84992|Acidimicrobiia	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
REGS1_k127_2230978_7	1123376.AUIU01000012_gene1420	1.288e-81	283.0	COG0661@1|root,COG0661@2|Bacteria,3J0ZH@40117|Nitrospirae	40117|Nitrospirae	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
REGS1_k127_2230978_3	404380.Gbem_0098	1.861e-127	416.0	COG0042@1|root,COG0042@2|Bacteria,1MUSM@1224|Proteobacteria	1224|Proteobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs	dusC	GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
REGS1_k127_2230978_12	316067.Geob_1177	1.086e-30	123.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,42V3W@68525|delta/epsilon subdivisions,2WREM@28221|Deltaproteobacteria,43SRY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
REGS1_k127_2230978_5	443144.GM21_0880	8.338e-90	311.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
REGS1_k127_2230978_0	398767.Glov_3566	0.0	1567.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42NDJ@68525|delta/epsilon subdivisions,2WJSH@28221|Deltaproteobacteria,43TQ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_2230978_9	398767.Glov_1589	5.471e-60	222.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria	1224|Proteobacteria	T	FHA Domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
REGS1_k127_2230978_11	1485545.JQLW01000006_gene295	1.259e-33	140.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria	1224|Proteobacteria	T	PFAM Forkhead-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
REGS1_k127_2230978_8	398767.Glov_1588	1.012e-78	271.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	protein phosphatase 2C domain protein	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
REGS1_k127_2230978_1	398767.Glov_1587	2.509e-309	968.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
REGS1_k127_2230978_6	449447.MAE_46420	2.833e-83	297.0	COG1928@1|root,COG1928@2|Bacteria	2|Bacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
REGS1_k127_2230978_4	314230.DSM3645_14360	5.062e-126	407.0	COG1215@1|root,COG1215@2|Bacteria,2IZ7V@203682|Planctomycetes	203682|Planctomycetes	M	COG0463 Glycosyltransferases involved in cell wall	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
REGS1_k127_2230978_2	452637.Oter_3990	8.172e-141	455.0	COG0451@1|root,COG0451@2|Bacteria,46TXA@74201|Verrucomicrobia	74201|Verrucomicrobia	M	Male sterility protein	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
REGS1_k127_2230978_10	497965.Cyan7822_3235	3.455e-53	188.0	COG0451@1|root,COG0451@2|Bacteria,1G0IT@1117|Cyanobacteria,3KJ7S@43988|Cyanothece	1117|Cyanobacteria	M	PFAM NAD-dependent epimerase dehydratase	-	-	5.1.3.10	ko:K12454	ko00520,map00520	-	R04266	RC00528	ko00000,ko00001,ko01000	-	-	-	Epimerase
REGS1_k127_2257770_9	1538644.KO02_13905	1.852e-17	89.0	2CII3@1|root,32S83@2|Bacteria,4NT5V@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2257770_11	443143.GM18_0495	0.0001516	48.0	2E8BS@1|root,332QF@2|Bacteria,1R3CW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2257770_8	398767.Glov_2577	5.618e-18	90.0	2E8BS@1|root,334EE@2|Bacteria,1N75E@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2257770_7	1244869.H261_05789	4.945e-25	115.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,2TREZ@28211|Alphaproteobacteria,2JT8P@204441|Rhodospirillales	204441|Rhodospirillales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_2257770_4	1173263.Syn7502_01576	5.35e-138	450.0	COG0393@1|root,COG0393@2|Bacteria,1GC92@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
REGS1_k127_2257770_5	85643.Tmz1t_3959	9.102e-96	335.0	COG2905@1|root,COG5001@1|root,COG2905@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVC7@206389|Rhodocyclales	206389|Rhodocyclales	T	PAC sensor-containing diguanylate cyclase phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF,PAS,PAS_9
REGS1_k127_2257770_1	443144.GM21_1427	3.734e-183	581.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria	1224|Proteobacteria	P	Ammonium transporter	-	-	-	ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11.4	-	-	Ammonium_transp
REGS1_k127_2257770_2	644968.DFW101_3105	3.771e-165	529.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42PNI@68525|delta/epsilon subdivisions,2WJNF@28221|Deltaproteobacteria,2M9NW@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
REGS1_k127_2257770_3	443143.GM18_4304	2.686e-142	456.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
REGS1_k127_2257770_6	338966.Ppro_2508	6.167e-45	166.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,430DG@68525|delta/epsilon subdivisions,2WVPJ@28221|Deltaproteobacteria,43VAT@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2257770_0	316067.Geob_0436	1.726e-194	625.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
REGS1_k127_2259221_3	243231.GSU0608	1.74e-49	181.0	COG3894@1|root,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKC6@28221|Deltaproteobacteria,43TR4@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445
REGS1_k127_2259221_4	1499967.BAYZ01000076_gene842	1.251e-47	194.0	COG0457@1|root,COG0457@2|Bacteria,2NQJ6@2323|unclassified Bacteria	2|Bacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2,TPR_8
REGS1_k127_2259221_0	243231.GSU0609	6.159e-287	886.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,43RZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
REGS1_k127_2259221_1	269799.Gmet_0588	6.182e-102	351.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
REGS1_k127_2259221_2	316067.Geob_1423	1e-99	327.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,43U99@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
REGS1_k127_2309795_0	316067.Geob_2768	1.794e-212	669.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_2309795_3	269799.Gmet_0349	6.391e-52	194.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WMNG@28221|Deltaproteobacteria,43UNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
REGS1_k127_2309795_2	316067.Geob_3261	3.34e-110	363.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,43AJV@68525|delta/epsilon subdivisions,2X601@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
REGS1_k127_2309795_1	243231.GSU3366	8.023e-147	467.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
REGS1_k127_2318107_10	316067.Geob_3404	4.527e-98	324.0	COG4117@1|root,COG4117@2|Bacteria,1R5GN@1224|Proteobacteria,42QVP@68525|delta/epsilon subdivisions,2WMT7@28221|Deltaproteobacteria,43TYI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Prokaryotic cytochrome b561	cbcB	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_2318107_8	443143.GM18_2131	1.256e-146	473.0	COG2267@1|root,COG2267@2|Bacteria,1QUW0@1224|Proteobacteria,43CDS@68525|delta/epsilon subdivisions,2X7PQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Abhydrolase_1
REGS1_k127_2318107_4	316067.Geob_3149	2.141e-179	566.0	COG0332@1|root,COG0332@2|Bacteria,1P9I2@1224|Proteobacteria,42PE7@68525|delta/epsilon subdivisions,2WJZZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	fabH-3	-	-	ko:K22317	-	-	-	-	ko00000	-	-	-	ACP_syn_III,ACP_syn_III_C,Thiolase_N
REGS1_k127_2318107_5	443143.GM18_3972	5.216e-169	534.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,43T66@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
REGS1_k127_2318107_1	316067.Geob_1300	6.828e-227	708.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,43SX3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
REGS1_k127_2318107_9	316067.Geob_1301	1.076e-135	436.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria,43TXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_2318107_13	404380.Gbem_0405	5.814e-50	185.0	COG1648@1|root,COG1648@2|Bacteria,1RB3H@1224|Proteobacteria,42QT2@68525|delta/epsilon subdivisions,2WN1F@28221|Deltaproteobacteria,43UXX@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Sirohaem biosynthesis protein central	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,Sirohm_synth_M
REGS1_k127_2318107_17	1279017.AQYJ01000026_gene380	1.183e-05	49.0	2DSB0@1|root,33FBC@2|Bacteria,1NGBC@1224|Proteobacteria,1SH3C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2318107_15	1121448.DGI_0425	2.059e-16	82.0	2EHUE@1|root,33BK1@2|Bacteria,1QTGN@1224|Proteobacteria,4369K@68525|delta/epsilon subdivisions,2X0U9@28221|Deltaproteobacteria,2MDF0@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2318107_6	316067.Geob_1664	7.482e-159	511.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,43TYH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
REGS1_k127_2318107_7	316067.Geob_0856	6.544e-154	498.0	COG1538@1|root,COG1538@2|Bacteria,1R6VY@1224|Proteobacteria,430DM@68525|delta/epsilon subdivisions,2WWMP@28221|Deltaproteobacteria,43VIN@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
REGS1_k127_2318107_3	269799.Gmet_3508	7.505e-185	586.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42SYF@68525|delta/epsilon subdivisions,2WPNQ@28221|Deltaproteobacteria,43W04@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
REGS1_k127_2318107_0	316067.Geob_0858	0.0	1827.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
REGS1_k127_2318107_12	243231.GSU0831	3.231e-55	196.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
REGS1_k127_2318107_11	316067.Geob_3768	3.483e-86	293.0	COG4313@1|root,COG4313@2|Bacteria,1NW7I@1224|Proteobacteria,42ZUG@68525|delta/epsilon subdivisions,2WVAI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
REGS1_k127_2318107_2	269799.Gmet_3205	3.823e-213	667.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_2334573_0	269799.Gmet_1733	8.275e-135	437.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,42N1Q@68525|delta/epsilon subdivisions,2WJJS@28221|Deltaproteobacteria,43TSG@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
REGS1_k127_2334573_4	398767.Glov_0182	2.289e-69	238.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,43UNY@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA-2	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
REGS1_k127_2334573_5	243231.GSU2409	1.312e-56	202.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,43V33@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
REGS1_k127_2334573_6	398767.Glov_0184	5.013e-50	184.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
REGS1_k127_2334573_7	243231.GSU0691	1.455e-48	176.0	COG0023@1|root,COG0023@2|Bacteria,1MZ8T@1224|Proteobacteria,42TW6@68525|delta/epsilon subdivisions,2WQNT@28221|Deltaproteobacteria,43SNP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Translation initiation factor SUI1	yciH	-	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
REGS1_k127_2334573_1	589865.DaAHT2_0018	4.353e-112	390.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_2334573_2	335543.Sfum_1995	1.509e-111	371.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42MDS@68525|delta/epsilon subdivisions,2WJM3@28221|Deltaproteobacteria,2MR90@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
REGS1_k127_2334573_3	880073.Calab_0988	3.148e-98	340.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,2NPAA@2323|unclassified Bacteria	2|Bacteria	S	AMMECR1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
REGS1_k127_2378241_11	398767.Glov_2700	7.285e-55	201.0	COG2199@1|root,COG3706@2|Bacteria,1RAKG@1224|Proteobacteria,42QYD@68525|delta/epsilon subdivisions,2WN6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
REGS1_k127_2378241_3	398767.Glov_1611	1.026e-192	612.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,43SUM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	pyridine nucleotide-disulphide oxidoreductase dimerisation region	lpdA-1	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_2378241_8	398767.Glov_1008	1.517e-95	314.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,42QW0@68525|delta/epsilon subdivisions,2WMZW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	3-dmu-9_3-mt
REGS1_k127_2378241_6	269799.Gmet_2766	1.208e-141	460.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,42N18@68525|delta/epsilon subdivisions,2WJSK@28221|Deltaproteobacteria,43RXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2766	2-oxoacid_dh,Biotin_lipoyl,E3_binding
REGS1_k127_2378241_0	243231.GSU2449	0.0	1128.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,42NY6@68525|delta/epsilon subdivisions,2WJSE@28221|Deltaproteobacteria,43S8Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E1 subunit	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
REGS1_k127_2378241_7	243231.GSU0997	3.098e-101	336.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,42R8W@68525|delta/epsilon subdivisions,2WMZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
REGS1_k127_2378241_10	1232410.KI421428_gene1027	1.025e-85	287.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,42QWV@68525|delta/epsilon subdivisions,2WMPT@28221|Deltaproteobacteria,43SFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
REGS1_k127_2378241_12	395961.Cyan7425_4809	1.77e-50	190.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,3KGBC@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_2378241_13	316067.Geob_1946	6.782e-50	180.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,42V4I@68525|delta/epsilon subdivisions,2WRJJ@28221|Deltaproteobacteria,43V55@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
REGS1_k127_2378241_1	316067.Geob_1944	2.985e-260	824.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43T1R@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
REGS1_k127_2378241_14	378806.STAUR_6565	8.972e-50	202.0	COG0840@1|root,COG3850@1|root,COG0840@2|Bacteria,COG3850@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
REGS1_k127_2378241_4	443143.GM18_2506	1.813e-160	512.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,42MQV@68525|delta/epsilon subdivisions,2WIZC@28221|Deltaproteobacteria,43S0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
REGS1_k127_2378241_2	269799.Gmet_3223	1.717e-201	635.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,43SUF@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_2378241_16	926569.ANT_21400	9.562e-30	121.0	COG4737@1|root,COG4737@2|Bacteria	2|Bacteria	G	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	RelE
REGS1_k127_2378241_18	384676.PSEEN4322	2.349e-19	91.0	COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,1S97H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulator	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_31
REGS1_k127_2378241_17	398767.Glov_2139	8.492e-23	100.0	COG4226@1|root,COG4226@2|Bacteria,1MZE7@1224|Proteobacteria,42SRH@68525|delta/epsilon subdivisions,2WPUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
REGS1_k127_2378241_9	316067.Geob_0298	1.041e-88	302.0	COG0760@1|root,COG0760@2|Bacteria,1R5NR@1224|Proteobacteria	1224|Proteobacteria	O	Peptidylprolyl isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Rotamase,Rotamase_2,Rotamase_3
REGS1_k127_2378241_5	1242864.D187_007813	5.178e-148	484.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_2380152_1	243231.GSU0579	0.0	1082.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,42M6A@68525|delta/epsilon subdivisions,2WJIT@28221|Deltaproteobacteria,43UB3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	glycyl-tRNA aminoacylation	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
REGS1_k127_2380152_5	398767.Glov_1023	5.542e-185	580.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,42MNQ@68525|delta/epsilon subdivisions,2WJJW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_2942	tRNA-synt_2e
REGS1_k127_2380152_4	316067.Geob_2855	9.459e-244	756.0	COG2223@1|root,COG2223@2|Bacteria,1MWC7@1224|Proteobacteria,42P53@68525|delta/epsilon subdivisions,2WJ2U@28221|Deltaproteobacteria,43TBP@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
REGS1_k127_2380152_10	269799.Gmet_2850	3.343e-95	320.0	COG0726@1|root,COG0726@2|Bacteria,1RCWD@1224|Proteobacteria,42R0P@68525|delta/epsilon subdivisions,2WNBS@28221|Deltaproteobacteria,43U58@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_2380152_15	1121448.DGI_0425	1.329e-10	64.0	2EHUE@1|root,33BK1@2|Bacteria,1QTGN@1224|Proteobacteria,4369K@68525|delta/epsilon subdivisions,2X0U9@28221|Deltaproteobacteria,2MDF0@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2380152_0	404380.Gbem_0330	0.0	1219.0	COG2203@1|root,COG3604@1|root,COG2203@2|Bacteria,COG3604@2|Bacteria,1NRKF@1224|Proteobacteria,42YSP@68525|delta/epsilon subdivisions,2WTUU@28221|Deltaproteobacteria,43SY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,Sigma54_activat
REGS1_k127_2380152_2	316067.Geob_1382	8.257e-273	851.0	2EWA0@1|root,33PNR@2|Bacteria,1NSPR@1224|Proteobacteria,42YN1@68525|delta/epsilon subdivisions,2WTJI@28221|Deltaproteobacteria,43U3D@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2380152_8	443143.GM18_0415	7.787e-107	352.0	COG1235@1|root,COG1235@2|Bacteria,1MVJH@1224|Proteobacteria,42W9U@68525|delta/epsilon subdivisions,2WRHS@28221|Deltaproteobacteria,43T6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
REGS1_k127_2380152_11	316067.Geob_1384	3.141e-87	300.0	COG0438@1|root,COG0438@2|Bacteria,1N2C6@1224|Proteobacteria,42UQ0@68525|delta/epsilon subdivisions,2WQU7@28221|Deltaproteobacteria,43UCH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_2380152_12	338966.Ppro_0892	3.491e-75	261.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42MZV@68525|delta/epsilon subdivisions,2X7R4@28221|Deltaproteobacteria,43VYG@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TOBE domain	-	-	3.6.3.30,3.6.3.55	ko:K02010,ko:K06857	ko02010,map02010	M00186,M00190	R10531	RC00002	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10,3.A.1.6.2,3.A.1.6.4	-	-	ABC_tran
REGS1_k127_2380152_9	338966.Ppro_0891	1.571e-96	321.0	COG4662@1|root,COG4662@2|Bacteria,1MZVS@1224|Proteobacteria,42N6T@68525|delta/epsilon subdivisions,2WMKR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	tupB	-	-	ko:K05773	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	BPD_transp_1
REGS1_k127_2380152_7	338966.Ppro_1542	3.517e-115	377.0	COG2998@1|root,COG2998@2|Bacteria,1MVSF@1224|Proteobacteria,42NK5@68525|delta/epsilon subdivisions,2WM49@28221|Deltaproteobacteria,43VZU@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K05772	ko02010,map02010	M00186	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.2,3.A.1.6.4	-	-	PBP_like_2
REGS1_k127_2380152_14	1380394.JADL01000008_gene3633	7.168e-28	119.0	COG2050@1|root,COG2050@2|Bacteria,1MZB4@1224|Proteobacteria,2U9Y0@28211|Alphaproteobacteria,2JTQ2@204441|Rhodospirillales	204441|Rhodospirillales	Q	protein, possibly involved in aromatic compounds catabolism	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_2380152_3	316067.Geob_0543	9.072e-262	811.0	COG0422@1|root,COG0422@2|Bacteria,1R3YC@1224|Proteobacteria,42PF8@68525|delta/epsilon subdivisions,2WK26@28221|Deltaproteobacteria,43S15@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L- methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by	thiC-2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.23	ko:K22466	-	-	-	-	ko00000,ko01000	-	-	-	ThiC_Rad_SAM
REGS1_k127_239628_0	443143.GM18_1679	5.035e-172	555.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,43TZI@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	HTH_8,PAS_4,PAS_9,Sigma54_activat
REGS1_k127_239628_5	269799.Gmet_1852	8.386e-13	76.0	COG3629@1|root,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
REGS1_k127_239628_6	1122604.JONR01000011_gene3699	5.767e-12	72.0	2DP0Y@1|root,3302T@2|Bacteria,1N6ZP@1224|Proteobacteria,1SSW5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LTXXQ motif family protein	-	-	-	-	-	-	-	-	-	-	-	-	LTXXQ
REGS1_k127_239628_2	472759.Nhal_2557	3.215e-70	250.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,1S3T8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ribonuclease BN	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
REGS1_k127_239628_1	525897.Dbac_2185	9.797e-82	279.0	COG2823@1|root,COG2823@2|Bacteria,1PCIJ@1224|Proteobacteria,42RMP@68525|delta/epsilon subdivisions,2X5PZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	bacterial OsmY and nodulation domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
REGS1_k127_239628_3	56780.SYN_03004	2.946e-52	200.0	COG3064@1|root,COG3064@2|Bacteria,1R7D3@1224|Proteobacteria,42Y44@68525|delta/epsilon subdivisions,2X6IP@28221|Deltaproteobacteria,2MRQW@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_239628_4	1206733.BAGC01000108_gene6398	1.064e-17	91.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4FW39@85025|Nocardiaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_2482229_6	1121918.ARWE01000001_gene205	4.222e-121	396.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,42NN0@68525|delta/epsilon subdivisions,2WM14@28221|Deltaproteobacteria,43UIC@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DnaA_C,Y1_Tnp
REGS1_k127_2482229_13	1116472.MGMO_121c00080	1.476e-19	92.0	COG3668@1|root,COG3668@2|Bacteria,1N2I9@1224|Proteobacteria,1SBPZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	plasmid stabilization	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
REGS1_k127_2482229_10	1116472.MGMO_121c00090	1.434e-27	114.0	COG3609@1|root,COG3609@2|Bacteria,1NA19@1224|Proteobacteria,1SCG2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	addiction module antidote protein	-	-	-	ko:K07746	-	-	-	-	ko00000,ko02048	-	-	-	ParD_antitoxin
REGS1_k127_2482229_14	743299.Acife_0043	1.202e-10	65.0	COG5304@1|root,COG5304@2|Bacteria,1N9U3@1224|Proteobacteria,1SSRU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
REGS1_k127_2482229_4	243231.GSU2403	5.29e-148	474.0	COG5397@1|root,COG5397@2|Bacteria,1R4MR@1224|Proteobacteria,430NS@68525|delta/epsilon subdivisions,2WVXQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
REGS1_k127_2482229_3	398767.Glov_0434	1.034e-224	700.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,42MYW@68525|delta/epsilon subdivisions,2WJD1@28221|Deltaproteobacteria,43TZC@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh_C,ATP-grasp,Epimerase
REGS1_k127_2482229_0	243231.GSU2762	1.442e-293	904.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,42M9Z@68525|delta/epsilon subdivisions,2WIYZ@28221|Deltaproteobacteria,43U0G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
REGS1_k127_2482229_1	398767.Glov_2687	2.888e-278	862.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42N1B@68525|delta/epsilon subdivisions,2WJWS@28221|Deltaproteobacteria,43UDG@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM FAD dependent oxidoreductase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
REGS1_k127_2482229_5	243231.GSU2543	3.691e-131	423.0	COG0726@1|root,COG0726@2|Bacteria,1MWUE@1224|Proteobacteria,42QSJ@68525|delta/epsilon subdivisions,2WQ2V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_2482229_7	443143.GM18_0664	1.198e-71	249.0	COG4123@1|root,COG4123@2|Bacteria,1MXEQ@1224|Proteobacteria,42SAA@68525|delta/epsilon subdivisions,2WPCM@28221|Deltaproteobacteria,43UP5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative RNA methylase family UPF0020	-	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
REGS1_k127_2482229_9	316067.Geob_1482	5.103e-40	154.0	COG5512@1|root,COG5512@2|Bacteria,1N6KK@1224|Proteobacteria,42TK4@68525|delta/epsilon subdivisions,2WQQS@28221|Deltaproteobacteria,43VF7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
REGS1_k127_2482229_12	243231.GSU0639	3.725e-25	107.0	28ISQ@1|root,33DSE@2|Bacteria,1NJUV@1224|Proteobacteria,42XI4@68525|delta/epsilon subdivisions,2WT4N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2482229_11	443144.GM21_3496	1.195e-25	108.0	2DR4V@1|root,33A63@2|Bacteria,1NM2S@1224|Proteobacteria,42XKC@68525|delta/epsilon subdivisions,2WSQF@28221|Deltaproteobacteria,43VMX@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
REGS1_k127_2482229_2	316067.Geob_2289	1.727e-253	787.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42QFH@68525|delta/epsilon subdivisions,2WKWR@28221|Deltaproteobacteria,43UC3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	hpnJ	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_2482229_8	338966.Ppro_1338	1.75e-51	192.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,42TN9@68525|delta/epsilon subdivisions,2WRG0@28221|Deltaproteobacteria,43VFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	6-O-methylguanine DNA methyltransferase, DNA binding domain	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
REGS1_k127_2482462_7	743719.PaelaDRAFT_1826	1.121e-86	295.0	COG1028@1|root,COG1028@2|Bacteria,1UY5Y@1239|Firmicutes,4HE3G@91061|Bacilli,26QCY@186822|Paenibacillaceae	91061|Bacilli	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
REGS1_k127_2482462_8	269799.Gmet_1009	9.193e-66	228.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,42T3J@68525|delta/epsilon subdivisions,2X5P0@28221|Deltaproteobacteria,43W2U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
REGS1_k127_2482462_1	443143.GM18_3284	5.707e-320	991.0	COG0480@1|root,COG0480@2|Bacteria,1NSES@1224|Proteobacteria,42YHS@68525|delta/epsilon subdivisions,2WTPX@28221|Deltaproteobacteria,43T62@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA-2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_2482462_4	269799.Gmet_3221	1.966e-164	526.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_2482462_0	269799.Gmet_2829	0.0	1042.0	COG2982@1|root,COG2982@2|Bacteria,1MUME@1224|Proteobacteria,42M50@68525|delta/epsilon subdivisions,2WIP4@28221|Deltaproteobacteria,43SJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain of Unknown Function (DUF748)	-	-	-	-	-	-	-	-	-	-	-	-	DUF748
REGS1_k127_2482462_6	443144.GM21_2898	4.423e-89	309.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,Response_reg
REGS1_k127_2482462_3	443143.GM18_2098	4.285e-182	599.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,dCache_1
REGS1_k127_2482462_15	269799.Gmet_0243	4.147e-06	59.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	ko:K14340	-	-	-	-	ko00000,ko01000,ko01003	-	-	-	PMT_2
REGS1_k127_2482462_5	1232410.KI421420_gene3189	4.783e-106	353.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2WJG8@28221|Deltaproteobacteria,43TS1@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
REGS1_k127_2482462_9	179408.Osc7112_0403	1.014e-45	169.0	2CFUA@1|root,32S2G@2|Bacteria,1G7BR@1117|Cyanobacteria,1HBHX@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2482462_12	344747.PM8797T_30978	3.355e-21	105.0	COG2755@1|root,COG2755@2|Bacteria,2IZB1@203682|Planctomycetes	203682|Planctomycetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
REGS1_k127_2482462_11	338963.Pcar_1341	3.823e-27	118.0	2DQMK@1|root,337MR@2|Bacteria,1P0DK@1224|Proteobacteria,4316R@68525|delta/epsilon subdivisions,2WX43@28221|Deltaproteobacteria,43VJM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_2482462_13	1101192.KB910516_gene2949	6.502e-12	73.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,1JSQZ@119045|Methylobacteriaceae	28211|Alphaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,DUF4118,HATPase_c,HisKA,PAS_7,Response_reg
REGS1_k127_2482462_2	243231.GSU2888	2.389e-264	818.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42ZYI@68525|delta/epsilon subdivisions,2WVGV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
REGS1_k127_2510296_1	269799.Gmet_2815	9.677e-104	342.0	COG1215@1|root,COG1215@2|Bacteria,1PC79@1224|Proteobacteria,42QYP@68525|delta/epsilon subdivisions,2X6HG@28221|Deltaproteobacteria,43UDX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	hpnI	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
REGS1_k127_2510296_0	269799.Gmet_0602	1.864e-124	400.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,43TZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_2519729_1	316067.Geob_3729	6.197e-151	487.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
REGS1_k127_2519729_11	316067.Geob_1188	3.19e-23	103.0	COG5626@1|root,COG5626@2|Bacteria,1Q1CN@1224|Proteobacteria,42XSI@68525|delta/epsilon subdivisions,2WT03@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
REGS1_k127_2519729_3	316067.Geob_1189	1.689e-118	384.0	COG4887@1|root,COG4887@2|Bacteria,1RKM1@1224|Proteobacteria,42SU2@68525|delta/epsilon subdivisions,2WP4U@28221|Deltaproteobacteria,43UDW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1847
REGS1_k127_2519729_10	1232410.KI421423_gene1917	1.079e-34	151.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42NMK@68525|delta/epsilon subdivisions,2WK6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_2519729_2	443143.GM18_0306	1.062e-142	471.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PGC@68525|delta/epsilon subdivisions,2WKHK@28221|Deltaproteobacteria,43UFI@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains Cache_1, HAMP, PAS, PAS	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_9,dCache_1
REGS1_k127_2519729_7	338966.Ppro_2721	8.864e-61	214.0	COG3437@1|root,COG3437@2|Bacteria,1NW43@1224|Proteobacteria,43007@68525|delta/epsilon subdivisions,2WVGG@28221|Deltaproteobacteria,43UZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_2519729_4	316067.Geob_1191	7.312e-117	386.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2WPIT@28221|Deltaproteobacteria,43U0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
REGS1_k127_2519729_0	338966.Ppro_0616	1.058e-210	661.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,43SZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
REGS1_k127_2519729_8	316067.Geob_1193	1.637e-50	186.0	COG4765@1|root,COG4765@2|Bacteria,1N5MU@1224|Proteobacteria,42TQ6@68525|delta/epsilon subdivisions,2WR2C@28221|Deltaproteobacteria,43VB1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2155)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2155
REGS1_k127_2519729_5	243231.GSU0106	2.842e-115	380.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,42MTF@68525|delta/epsilon subdivisions,2WJ6X@28221|Deltaproteobacteria,43T9A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
REGS1_k127_2519729_6	269799.Gmet_3412	1.195e-111	367.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,43U5F@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ParB domain protein nuclease	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
REGS1_k127_2519729_9	316067.Geob_0452	1.418e-39	151.0	COG0711@1|root,COG0711@2|Bacteria,1NA9K@1224|Proteobacteria,42VN2@68525|delta/epsilon subdivisions,2WR8C@28221|Deltaproteobacteria,43VA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpX	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
REGS1_k127_2519729_12	443143.GM18_4419	3.329e-05	51.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WR6T@28221|Deltaproteobacteria,43V2P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpF	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
REGS1_k127_2560492_10	1125863.JAFN01000001_gene1063	1.063e-97	324.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_2560492_8	1121440.AUMA01000009_gene684	1.039e-143	462.0	COG0559@1|root,COG0559@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2M8YK@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_2560492_5	883.DvMF_1580	4.052e-169	540.0	COG0683@1|root,COG0683@2|Bacteria,1MWQB@1224|Proteobacteria,42PN2@68525|delta/epsilon subdivisions,2WM53@28221|Deltaproteobacteria,2M994@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	PFAM Extracellular ligand-binding receptor	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_2560492_4	243231.GSU2524	2.234e-206	652.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKFA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_2560492_3	243231.GSU2492	1.752e-313	982.0	COG5000@1|root,COG5000@2|Bacteria,1QUG9@1224|Proteobacteria,42P6A@68525|delta/epsilon subdivisions,2WJZ4@28221|Deltaproteobacteria,43U4U@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
REGS1_k127_2560492_9	338966.Ppro_0119	8.002e-128	417.0	COG1683@1|root,COG3272@1|root,COG1683@2|Bacteria,COG3272@2|Bacteria,1MXYZ@1224|Proteobacteria,42M4E@68525|delta/epsilon subdivisions,2WKFT@28221|Deltaproteobacteria,43TH1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1722)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1722,DUF523
REGS1_k127_2560492_6	1232410.KI421425_gene1538	5.42e-160	527.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,43T80@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
REGS1_k127_2560492_20	1121935.AQXX01000129_gene1819	9.323e-22	103.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,1SDBT@1236|Gammaproteobacteria,1XM5F@135619|Oceanospirillales	135619|Oceanospirillales	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
REGS1_k127_2560492_19	1121396.KB892902_gene2326	1.434e-22	114.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2WJCX@28221|Deltaproteobacteria,2MHUJ@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HATPase_c,HisKA,Hpt,Response_reg
REGS1_k127_2560492_16	243231.GSU0253	5.333e-48	195.0	COG2203@1|root,COG4585@1|root,COG5002@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,1PEPF@1224|Proteobacteria,439XC@68525|delta/epsilon subdivisions,2X1UM@28221|Deltaproteobacteria,43UUE@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,PAS_3
REGS1_k127_2560492_15	243231.GSU0254	2.522e-55	203.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42RQX@68525|delta/epsilon subdivisions,2WNM1@28221|Deltaproteobacteria,43U8H@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_2560492_0	443143.GM18_1371	0.0	1150.0	COG2304@1|root,COG3419@1|root,COG2304@2|Bacteria,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions	1224|Proteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC,PA14
REGS1_k127_2560492_18	316067.Geob_3076	9.139e-28	119.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	fimU	-	-	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.15.2	-	-	N_methyl
REGS1_k127_2560492_11	443143.GM18_1374	7.726e-94	321.0	COG2165@1|root,COG2165@2|Bacteria,1QZ60@1224|Proteobacteria,43CGU@68525|delta/epsilon subdivisions,2X7S0@28221|Deltaproteobacteria,43VYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
REGS1_k127_2560492_14	443143.GM18_1375	7.101e-56	201.0	2E6Z6@1|root,331IC@2|Bacteria,1NY0D@1224|Proteobacteria,430VK@68525|delta/epsilon subdivisions,2WVKD@28221|Deltaproteobacteria,43VJN@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2560492_1	269799.Gmet_1259	1.236e-317	976.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,43U65@69541|Desulfuromonadales	28221|Deltaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
REGS1_k127_2560492_2	269799.Gmet_1260	1.174e-315	972.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,42M1X@68525|delta/epsilon subdivisions,2WJA2@28221|Deltaproteobacteria,43SU0@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
REGS1_k127_2560492_12	243231.GSU1910	7.562e-85	283.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,42RRU@68525|delta/epsilon subdivisions,2WNBY@28221|Deltaproteobacteria,43TG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TIGRFAM acetolactate synthase, small subunit	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
REGS1_k127_2560492_7	1121935.AQXX01000141_gene2013	5.529e-159	507.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,1XIH7@135619|Oceanospirillales	135619|Oceanospirillales	EH	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
REGS1_k127_2560492_13	269799.Gmet_1263	1.008e-83	283.0	COG0688@1|root,COG0688@2|Bacteria,1MW45@1224|Proteobacteria,42SYM@68525|delta/epsilon subdivisions,2WP8C@28221|Deltaproteobacteria,43UT8@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
REGS1_k127_2560492_17	243231.GSU1907	2.676e-36	143.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,43SK7@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
REGS1_k127_2616300_9	338966.Ppro_1166	3.666e-168	533.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42NHN@68525|delta/epsilon subdivisions,2WJ4S@28221|Deltaproteobacteria,43TP0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome d ubiquinol oxidase, subunit II	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
REGS1_k127_2616300_2	243231.GSU1640	2.797e-214	673.0	COG1271@1|root,COG1271@2|Bacteria,1MV60@1224|Proteobacteria,42MB8@68525|delta/epsilon subdivisions,2WIW7@28221|Deltaproteobacteria,43UFE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome bd terminal oxidase subunit I	cydA	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
REGS1_k127_2616300_31	269799.Gmet_1931	2.361e-54	194.0	COG1959@1|root,COG1959@2|Bacteria,1MZ1C@1224|Proteobacteria,42SPF@68525|delta/epsilon subdivisions,2WPVC@28221|Deltaproteobacteria,43UWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
REGS1_k127_2616300_37	59196.RICGR_0477	7.222e-31	136.0	COG0666@1|root,COG0666@2|Bacteria,1RBYV@1224|Proteobacteria,1SE9G@1236|Gammaproteobacteria,1JG4X@118969|Legionellales	118969|Legionellales	S	Annotation was generated automatically without manual curation	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
REGS1_k127_2616300_33	269799.Gmet_0181	3.329e-49	179.0	COG3011@1|root,COG3011@2|Bacteria,1Q51G@1224|Proteobacteria,430BW@68525|delta/epsilon subdivisions,2WW0J@28221|Deltaproteobacteria,43V3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
REGS1_k127_2616300_35	443143.GM18_2168	3.871e-34	134.0	COG1186@1|root,COG1186@2|Bacteria,1ND5C@1224|Proteobacteria,430VS@68525|delta/epsilon subdivisions,2WW3U@28221|Deltaproteobacteria,43V60@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
REGS1_k127_2616300_7	316067.Geob_3434	4.049e-185	583.0	COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,42PQY@68525|delta/epsilon subdivisions,2WJXE@28221|Deltaproteobacteria,43UFB@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroF	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2375	DAHP_synth_1
REGS1_k127_2616300_23	398767.Glov_0755	1.013e-86	302.0	COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,1MVYT@1224|Proteobacteria,42QYW@68525|delta/epsilon subdivisions,2WN42@28221|Deltaproteobacteria,43SVR@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	LysM,YkuD
REGS1_k127_2616300_3	398767.Glov_3076	2.035e-210	662.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43TS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07715	ko02020,ko02024,map02020,map02024	M00502	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_2616300_12	338966.Ppro_3646	1.058e-155	500.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43E1J@68525|delta/epsilon subdivisions,2WM21@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_2616300_4	269799.Gmet_1913	2.457e-199	627.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,43TYY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM tRNA synthetase, class II (G, H, P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
REGS1_k127_2616300_13	443144.GM21_1165	6.795e-155	503.0	COG2199@1|root,COG2204@1|root,COG2204@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42UHW@68525|delta/epsilon subdivisions,2WQ01@28221|Deltaproteobacteria,43T6H@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_2616300_6	269799.Gmet_1915	6.578e-190	620.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,43TMI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
REGS1_k127_2616300_24	269799.Gmet_0261	4.952e-86	299.0	COG1846@1|root,COG1846@2|Bacteria,1NRG9@1224|Proteobacteria,42YC6@68525|delta/epsilon subdivisions,2WTKJ@28221|Deltaproteobacteria,43TP5@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
REGS1_k127_2616300_21	404380.Gbem_2504	1.017e-93	313.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WPGW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
REGS1_k127_2616300_20	443143.GM18_1071	5.435e-111	363.0	COG0765@1|root,COG0765@2|Bacteria,1MV3I@1224|Proteobacteria,42Q6W@68525|delta/epsilon subdivisions,2WQE2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K10002	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
REGS1_k127_2616300_18	443143.GM18_1070	6.032e-113	368.0	COG0765@1|root,COG0765@2|Bacteria,1MUVX@1224|Proteobacteria,42S1H@68525|delta/epsilon subdivisions,2X5V2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM polar amino acid ABC transporter, inner membrane subunit	-	-	-	ko:K02029,ko:K10003	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	BPD_transp_1
REGS1_k127_2616300_15	443143.GM18_3771	1.067e-139	448.0	COG0834@1|root,COG0834@2|Bacteria,1MVT6@1224|Proteobacteria,42PW4@68525|delta/epsilon subdivisions,2WJPM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	ET	Belongs to the bacterial solute-binding protein 3 family	-	-	-	ko:K02030,ko:K10001	ko02010,ko02020,map02010,map02020	M00230,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.19,3.A.1.3.4	-	-	SBP_bac_3
REGS1_k127_2616300_17	443143.GM18_3770	3.003e-122	396.0	COG1126@1|root,COG1126@2|Bacteria,1MU9Q@1224|Proteobacteria,42M0S@68525|delta/epsilon subdivisions,2WITR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter related	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
REGS1_k127_2616300_25	338966.Ppro_3004	6.384e-74	252.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42ZFF@68525|delta/epsilon subdivisions,2WUTR@28221|Deltaproteobacteria,43UTB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
REGS1_k127_2616300_5	338966.Ppro_3003	3.145e-199	632.0	COG2252@1|root,COG2252@2|Bacteria,1MUV0@1224|Proteobacteria,42MAE@68525|delta/epsilon subdivisions,2WKFF@28221|Deltaproteobacteria,43T88@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Xanthine uracil vitamin C permease	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
REGS1_k127_2616300_11	316067.Geob_3211	2.338e-159	515.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42NMK@68525|delta/epsilon subdivisions,2WK6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_2616300_16	316067.Geob_3210	1.005e-125	420.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
REGS1_k127_2616300_30	316067.Geob_3206	1.199e-55	208.0	COG2984@1|root,COG2984@2|Bacteria	2|Bacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
REGS1_k127_2616300_10	316067.Geob_3207	8.734e-166	541.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,43CDT@68525|delta/epsilon subdivisions,2X7PR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug
REGS1_k127_2616300_28	316067.Geob_3206	6.478e-60	218.0	COG2984@1|root,COG2984@2|Bacteria	2|Bacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
REGS1_k127_2616300_8	316067.Geob_3207	3.671e-175	569.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,43CDT@68525|delta/epsilon subdivisions,2X7PR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug
REGS1_k127_2616300_14	316067.Geob_3209	2.351e-149	484.0	COG0641@1|root,COG0641@2|Bacteria,1R7G1@1224|Proteobacteria,42PI5@68525|delta/epsilon subdivisions,2WIK2@28221|Deltaproteobacteria,43T2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_2616300_34	1115515.EV102420_08_01830	3.811e-34	139.0	COG1397@1|root,COG2453@1|root,COG1397@2|Bacteria,COG2453@2|Bacteria,1NTUR@1224|Proteobacteria,1RMPE@1236|Gammaproteobacteria,3XP4M@561|Escherichia	1236|Gammaproteobacteria	O	hydrolase activity	yegU	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
REGS1_k127_2616300_42	324057.Pjdr2_0450	6.49e-11	67.0	COG0745@1|root,COG0745@2|Bacteria,1VTZW@1239|Firmicutes,4HVB2@91061|Bacilli,26UYI@186822|Paenibacillaceae	91061|Bacilli	T	consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_2616300_36	1158762.KB898056_gene108	4.627e-34	139.0	COG2453@1|root,COG2453@2|Bacteria,1N0H0@1224|Proteobacteria,1S9JV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	CDKN3,DSPc
REGS1_k127_2616300_29	398767.Glov_2339	2.448e-59	238.0	COG1361@1|root,COG3055@1|root,COG4409@1|root,COG4932@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG4409@2|Bacteria,COG4932@2|Bacteria,1R5HW@1224|Proteobacteria,42R1Y@68525|delta/epsilon subdivisions,2WMXD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
REGS1_k127_2616300_38	177437.HRM2_45380	2.54e-23	119.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42R3Z@68525|delta/epsilon subdivisions,2WN4D@28221|Deltaproteobacteria,2MJKG@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
REGS1_k127_2616300_43	1123236.KB899382_gene2272	1.801e-07	66.0	COG1680@1|root,COG2730@1|root,COG1680@2|Bacteria,COG2730@2|Bacteria,1MWHS@1224|Proteobacteria,1RRQF@1236|Gammaproteobacteria,46627@72275|Alteromonadaceae	1236|Gammaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	ASH,Beta-lactamase
REGS1_k127_2616300_41	222534.KB893670_gene3882	1.215e-11	80.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Glyco_hyd_101C,Glyco_hydro_101,Glyco_hydro_43,NPCBM,NPCBM_assoc,RicinB_lectin_2
REGS1_k127_2616300_26	335543.Sfum_2358	1.401e-71	267.0	COG2849@1|root,COG2849@2|Bacteria	2|Bacteria	-	-	-	-	2.4.1.52	ko:K00712	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	DUF285,Glycos_transf_1,MORN_2
REGS1_k127_2616300_1	269799.Gmet_0702	2.715e-234	730.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42Z3B@68525|delta/epsilon subdivisions,2WUA8@28221|Deltaproteobacteria,43UF5@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domains REC, sigma54 interaction, HTH8	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_2616300_19	338966.Ppro_2024	6.899e-112	371.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2WJ8E@28221|Deltaproteobacteria,43TGZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
REGS1_k127_2616300_27	243231.GSU2020	6.234e-60	211.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,42SQQ@68525|delta/epsilon subdivisions,2WPIW@28221|Deltaproteobacteria,43SJ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
REGS1_k127_2616300_0	316067.Geob_3056	2.483e-268	830.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,42M14@68525|delta/epsilon subdivisions,2WIN7@28221|Deltaproteobacteria,43TSY@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Carbamoyl-phosphate synthetase large chain domain protein	accC	-	6.3.4.14,6.4.1.1,6.4.1.2	ko:K01959,ko:K01961	ko00020,ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko01230,map00020,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212,map01230	M00082,M00173,M00376,M00620	R00344,R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
REGS1_k127_2616300_32	269799.Gmet_0985	4.969e-53	189.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,43VAZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
REGS1_k127_2619160_0	316067.Geob_0384	2.052e-319	995.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
REGS1_k127_2619160_2	316067.Geob_0383	5.064e-180	567.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,43UJ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
REGS1_k127_2619160_4	76114.ebD26	2.642e-38	148.0	COG2020@1|root,COG2020@2|Bacteria,1QVIW@1224|Proteobacteria,2VX8F@28216|Betaproteobacteria	28216|Betaproteobacteria	O	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_2619160_3	316067.Geob_1189	2.199e-117	381.0	COG4887@1|root,COG4887@2|Bacteria,1RKM1@1224|Proteobacteria,42SU2@68525|delta/epsilon subdivisions,2WP4U@28221|Deltaproteobacteria,43UDW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1847
REGS1_k127_2619160_5	316067.Geob_1188	1.59e-24	106.0	COG5626@1|root,COG5626@2|Bacteria,1Q1CN@1224|Proteobacteria,42XSI@68525|delta/epsilon subdivisions,2WT03@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
REGS1_k127_2619160_1	243231.GSU0102	7.123e-258	807.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
REGS1_k127_2641954_12	316067.Geob_2510	1.19e-96	322.0	COG0778@1|root,COG2768@1|root,COG0778@2|Bacteria,COG2768@2|Bacteria,1R4E3@1224|Proteobacteria,42RVJ@68525|delta/epsilon subdivisions,2WNCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Nitroreductase
REGS1_k127_2641954_24	265729.GS18_0200925	6.341e-15	83.0	COG1335@1|root,COG1335@2|Bacteria,1VEGS@1239|Firmicutes,4HR3B@91061|Bacilli,1ZHUU@1386|Bacillus	91061|Bacilli	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
REGS1_k127_2641954_20	1499967.BAYZ01000080_gene894	9.926e-31	126.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
REGS1_k127_2641954_11	338966.Ppro_1843	2.609e-99	331.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria,43TSZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
REGS1_k127_2641954_1	338966.Ppro_2535	8.588e-214	674.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43TM1@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
REGS1_k127_2641954_13	485913.Krac_8864	5.343e-77	267.0	COG2521@1|root,COG2521@2|Bacteria,2G7RX@200795|Chloroflexi	200795|Chloroflexi	S	Methyltransferase domain	-	-	-	ko:K06983	-	-	-	-	ko00000	-	-	-	Methyltransf_11
REGS1_k127_2641954_32	1463887.KL589953_gene47	2.897e-06	55.0	COG1765@1|root,COG1765@2|Bacteria,2IFY4@201174|Actinobacteria	201174|Actinobacteria	O	PFAM OsmC family protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
REGS1_k127_2641954_27	111781.Lepto7376_3032	2.196e-09	67.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H82F@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,Hpt,PAS_4,Response_reg
REGS1_k127_2641954_3	338963.Pcar_1599	1.695e-183	586.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MID@68525|delta/epsilon subdivisions,2WJYT@28221|Deltaproteobacteria,43UJC@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
REGS1_k127_2641954_19	316067.Geob_2293	3.617e-33	132.0	COG0793@1|root,COG0793@2|Bacteria,1NZYK@1224|Proteobacteria,431RH@68525|delta/epsilon subdivisions,2WWR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
REGS1_k127_2641954_16	269799.Gmet_2414	3.535e-60	210.0	COG2510@1|root,COG2510@2|Bacteria,1NDZV@1224|Proteobacteria,42V6K@68525|delta/epsilon subdivisions,2WRTX@28221|Deltaproteobacteria,43UXY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_2641954_9	316067.Geob_2290	9.761e-105	347.0	COG3394@1|root,COG3394@2|Bacteria,1PP3A@1224|Proteobacteria,42R6K@68525|delta/epsilon subdivisions,2WN1Q@28221|Deltaproteobacteria,43SXQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM YdjC family protein	hpnK	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
REGS1_k127_2641954_8	316067.Geob_0763	2.345e-105	351.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_2641954_7	316067.Geob_0764	3.803e-106	349.0	COG3245@1|root,COG3245@2|Bacteria,1RJCX@1224|Proteobacteria	1224|Proteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_2641954_0	269799.Gmet_2851	0.0	1310.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,43S73@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_2641954_23	398767.Glov_2707	2.914e-16	80.0	COG1146@1|root,COG1146@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FeS,Fe_hyd_lg_C,Fer2_4,Fer2_BFD,Fer4,Fer4_4,Fer4_6,Fer4_7,Nitroreductase,Pyr_redox_2
REGS1_k127_2641954_2	269799.Gmet_2853	1.922e-187	590.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria,43UA0@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	TIGRFAM branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
REGS1_k127_2641954_5	269799.Gmet_2854	1.104e-127	414.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,43TCQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_2641954_6	269799.Gmet_2855	1.564e-113	370.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
REGS1_k127_2641954_33	1089553.Tph_c21860	0.0004084	48.0	COG1476@1|root,COG1476@2|Bacteria,1VEM3@1239|Firmicutes,24QKH@186801|Clostridia	186801|Clostridia	K	PFAM Helix-turn-helix	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
REGS1_k127_2641954_22	316067.Geob_0809	1.034e-19	95.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	porX	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	PglZ,Response_reg
REGS1_k127_2641954_10	338966.Ppro_1384	7.42e-100	331.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,42NFH@68525|delta/epsilon subdivisions,2WITT@28221|Deltaproteobacteria,43U4S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
REGS1_k127_2641954_14	937777.Deipe_3678	6.834e-77	265.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	tam	-	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23,Methyltransf_25,Methyltransf_31
REGS1_k127_2641954_17	316067.Geob_0901	6.32e-45	168.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,42PQF@68525|delta/epsilon subdivisions,2WMCA@28221|Deltaproteobacteria,43VF3@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
REGS1_k127_2641954_18	404380.Gbem_3499	1.993e-44	168.0	2ARAZ@1|root,2ZUT3@2|Bacteria,1RDFY@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF3332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3332
REGS1_k127_2641954_4	580332.Slit_0252	7.109e-180	586.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_2641954_30	1121441.AUCX01000033_gene307	3.41e-07	55.0	COG2881@1|root,COG2881@2|Bacteria,1N6EP@1224|Proteobacteria,42U9Y@68525|delta/epsilon subdivisions,2WQGR@28221|Deltaproteobacteria,2MAET@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	TIGRFAM MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Yip1,zinc_ribbon_4
REGS1_k127_2697663_1	269799.Gmet_2767	0.0	1305.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42Y60@68525|delta/epsilon subdivisions,2WUR1@28221|Deltaproteobacteria,43T95@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_2697663_20	316067.Geob_0435	6.281e-35	142.0	COG0745@1|root,COG0745@2|Bacteria	316067.Geob_0435|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2697663_21	269799.Gmet_1649	1.129e-29	126.0	COG2825@1|root,COG2825@2|Bacteria,1P2KB@1224|Proteobacteria,431PS@68525|delta/epsilon subdivisions,2WWWT@28221|Deltaproteobacteria,43VMK@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
REGS1_k127_2697663_24	666686.B1NLA3E_00775	2.568e-08	66.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,4HC17@91061|Bacilli,1ZCZ4@1386|Bacillus	91061|Bacilli	K	Belongs to the sigma-70 factor family. ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_2697663_25	398767.Glov_1269	5.931e-08	65.0	COG3170@1|root,COG3170@2|Bacteria,1NHGQ@1224|Proteobacteria,42X64@68525|delta/epsilon subdivisions,2WSMQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,zf-HC2
REGS1_k127_2697663_15	443143.GM18_3195	1.803e-65	227.0	2EE9W@1|root,3384B@2|Bacteria,1NCE1@1224|Proteobacteria,42VUH@68525|delta/epsilon subdivisions,2WSA1@28221|Deltaproteobacteria,43V30@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit	cbcS	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Paired_CXXCH_1
REGS1_k127_2697663_9	443143.GM18_3196	4.06e-138	443.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42QZ2@68525|delta/epsilon subdivisions,2WMS4@28221|Deltaproteobacteria,43T2N@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	cbcT	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11,Fer4_2,Fer4_3,Fer4_7
REGS1_k127_2697663_3	243231.GSU0070	9.69e-190	601.0	COG4881@1|root,COG4881@2|Bacteria,1QXMX@1224|Proteobacteria,43C41@68525|delta/epsilon subdivisions,2WKYD@28221|Deltaproteobacteria,43TBN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Polysulphide reductase, NrfD	cbcU	-	-	-	-	-	-	-	-	-	-	-	NrfD
REGS1_k127_2697663_5	316067.Geob_1610	1.281e-168	537.0	COG0436@1|root,COG0436@2|Bacteria,1MUHD@1224|Proteobacteria,43AII@68525|delta/epsilon subdivisions,2X5YR@28221|Deltaproteobacteria,43TWD@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
REGS1_k127_2697663_11	243231.GSU0140	8.398e-109	357.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
REGS1_k127_2697663_10	316067.Geob_1111	6.623e-135	444.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,43U9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
REGS1_k127_2697663_17	316067.Geob_1112	1.832e-60	213.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,42U6G@68525|delta/epsilon subdivisions,2WQDR@28221|Deltaproteobacteria,43SN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0195	PgpA
REGS1_k127_2697663_19	443143.GM18_4086	4.718e-46	171.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,43TC5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Competence-damaged protein	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
REGS1_k127_2697663_4	316067.Geob_1115	3.581e-187	588.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,43TMU@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
REGS1_k127_2697663_2	316067.Geob_1116	3.681e-194	610.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ28@28221|Deltaproteobacteria,43TYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	PFAM type II secretion system protein E	pilT-1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_2697663_22	443143.GM18_4090	2.672e-26	116.0	COG2137@1|root,COG2137@2|Bacteria,1QR86@1224|Proteobacteria,42XRV@68525|delta/epsilon subdivisions,2WSI7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Modulates RecA activity	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
REGS1_k127_2697663_0	269799.Gmet_0201	0.0	1349.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,43THC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
REGS1_k127_2697663_7	243231.GSU0149	2.007e-146	472.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1QXMY@1224|Proteobacteria,42W3X@68525|delta/epsilon subdivisions,2WTS7@28221|Deltaproteobacteria,43TUJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Motility response receiver histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_2697663_18	443144.GM21_0404	1.963e-53	189.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,43UZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_2697663_12	443143.GM18_3705	1.125e-92	309.0	COG0179@1|root,COG0179@2|Bacteria,1MVFA@1224|Proteobacteria,42S7E@68525|delta/epsilon subdivisions,2WKJ0@28221|Deltaproteobacteria,43SDP@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Fumarylacetoacetate (FAA) hydrolase family	ycgM	-	3.7.1.20	ko:K16165	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R01085	RC00326,RC00446	ko00000,ko00001,ko01000	-	-	-	FAA_hydrolase
REGS1_k127_2697663_16	1437425.CSEC_2379	5.83e-62	226.0	COG1651@1|root,COG1651@2|Bacteria,2JFUW@204428|Chlamydiae	204428|Chlamydiae	O	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4,VKOR
REGS1_k127_2697663_6	338966.Ppro_3477	2.483e-149	478.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2WUKR@28221|Deltaproteobacteria,43TXR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SMART Elongator protein 3 MiaB NifB	yhcC-2	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
REGS1_k127_2697663_14	316067.Geob_1586	3.541e-82	278.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42NTP@68525|delta/epsilon subdivisions,2WQME@28221|Deltaproteobacteria,43UPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	tenI	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
REGS1_k127_2697663_8	316067.Geob_1587	1.269e-140	449.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,42MNC@68525|delta/epsilon subdivisions,2WIUI@28221|Deltaproteobacteria,43TNT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
REGS1_k127_2697663_23	269799.Gmet_2933	6.558e-19	88.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2WSM2@28221|Deltaproteobacteria,43VNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_2700271_3	443143.GM18_3463	2.88e-144	470.0	2EUXR@1|root,33ND1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2700271_7	316067.Geob_1497	1.011e-94	318.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,43TDJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
REGS1_k127_2700271_8	398767.Glov_1381	9.04e-73	252.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42QGK@68525|delta/epsilon subdivisions,2WMC7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	PFAM Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
REGS1_k127_2700271_6	269799.Gmet_3455	1.256e-105	359.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
REGS1_k127_2700271_11	269799.Gmet_3454	2.046e-18	87.0	COG0425@1|root,COG0425@2|Bacteria	2|Bacteria	O	sulfur carrier activity	tusA-2	GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008	-	ko:K07112	-	-	-	-	ko00000	-	-	-	HTH_20,HTH_5,TusA
REGS1_k127_2700271_5	269799.Gmet_3453	4.408e-116	384.0	COG2391@1|root,COG2391@2|Bacteria,1MXSE@1224|Proteobacteria,42V4B@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Sulphur transport	soxT	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_2700271_2	243231.GSU0685	7.748e-178	560.0	COG0535@1|root,COG0535@2|Bacteria,1MXM1@1224|Proteobacteria,42PCW@68525|delta/epsilon subdivisions,2WMDU@28221|Deltaproteobacteria,43UIR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Domain of unknown function (DUF3463)	hpnH	-	-	-	-	-	-	-	-	-	-	-	DUF3463,Fer4_12,Fer4_14,Radical_SAM
REGS1_k127_2700271_1	243231.GSU0686	3.481e-289	901.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,42M35@68525|delta/epsilon subdivisions,2WIX5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
REGS1_k127_2700271_4	243231.GSU0687	2.053e-143	463.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,42NJT@68525|delta/epsilon subdivisions,2WM7E@28221|Deltaproteobacteria,43UJ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NmrA-like family	hpnA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
REGS1_k127_2700271_0	316067.Geob_3662	0.0	1018.0	COG1657@1|root,COG1657@2|Bacteria,1MUIP@1224|Proteobacteria,42Q4W@68525|delta/epsilon subdivisions,2WJ9H@28221|Deltaproteobacteria,43UJ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Squalene-hopene cyclase C-terminal domain	shc-1	-	4.2.1.129,5.4.99.17,5.4.99.7	ko:K01852,ko:K06045	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	M00101	R03199,R07322,R07323	RC00874,RC01850,RC01851	ko00000,ko00001,ko00002,ko01000	-	-	-	SQHop_cyclase_C,SQHop_cyclase_N
REGS1_k127_2700271_9	269799.Gmet_2819	1.653e-66	231.0	COG1033@1|root,COG2518@1|root,COG1033@2|Bacteria,COG2518@2|Bacteria,1QXNB@1224|Proteobacteria,43C4B@68525|delta/epsilon subdivisions,2X7ES@28221|Deltaproteobacteria,43UJS@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	MMPL family	hpnN	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
REGS1_k127_2799101_10	404380.Gbem_0077	3.692e-53	191.0	29UFS@1|root,30FSN@2|Bacteria,1RDI2@1224|Proteobacteria,42RWP@68525|delta/epsilon subdivisions,2WNB3@28221|Deltaproteobacteria,43UTE@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2799101_7	269799.Gmet_0019	4.518e-145	465.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,42M0C@68525|delta/epsilon subdivisions,2WMJ2@28221|Deltaproteobacteria,43TS8@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
REGS1_k127_2799101_11	768706.Desor_5227	6.911e-39	153.0	COG1392@1|root,COG1392@2|Bacteria,1UYRI@1239|Firmicutes,24BCU@186801|Clostridia,261YI@186807|Peptococcaceae	186801|Clostridia	P	phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
REGS1_k127_2799101_6	316067.Geob_0605	2.417e-146	469.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42Q5K@68525|delta/epsilon subdivisions,2X5HI@28221|Deltaproteobacteria,43UF4@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
REGS1_k127_2799101_4	398767.Glov_2272	1.356e-157	502.0	COG0451@1|root,COG0451@2|Bacteria,1P603@1224|Proteobacteria,42NGH@68525|delta/epsilon subdivisions,2WKS6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	3-Beta hydroxysteroid dehydrogenase isomerase	-	-	1.1.1.394,1.1.1.412	ko:K21271,ko:K22320	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD
REGS1_k127_2799101_1	338966.Ppro_3117	6.221e-227	715.0	COG0318@1|root,COG0318@2|Bacteria,1R5I6@1224|Proteobacteria,42MKC@68525|delta/epsilon subdivisions,2WK3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.1.3.1	ko:K22319	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding
REGS1_k127_2799101_2	243231.GSU0135	4.107e-189	593.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,42N17@68525|delta/epsilon subdivisions,2WJE8@28221|Deltaproteobacteria,43SYT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
REGS1_k127_2799101_0	316067.Geob_1298	9.447e-232	730.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,43U2R@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
REGS1_k127_2799101_13	443143.GM18_2606	3.191e-25	123.0	COG1629@1|root,COG2165@1|root,COG2165@2|Bacteria,COG4771@2|Bacteria	2|Bacteria	P	TonB-dependent receptor	pilV	GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840	-	ko:K02014,ko:K02456,ko:K02457,ko:K02458,ko:K10926,ko:K10930,ko:K10931	ko03070,ko05110,ko05111,map03070,map05110,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	1.B.14,3.A.15	-	-	FecR,N_methyl,Shufflon_N,TPR_16,TPR_8,TcpA
REGS1_k127_2799101_9	323259.Mhun_0486	3.677e-75	281.0	COG1404@1|root,arCOG00702@2157|Archaea,2XUT1@28890|Euryarchaeota,2NBHB@224756|Methanomicrobia	28890|Euryarchaeota	O	Subtilase family	hly	GO:0005575,GO:0005576	-	ko:K14645	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	PKD,Peptidase_S8,TAT_signal
REGS1_k127_2799101_16	1123059.KB823011_gene1408	6.646e-11	76.0	COG0747@1|root,COG3468@1|root,COG0747@2|Bacteria,COG3468@2|Bacteria,1R0VF@1224|Proteobacteria,2TYU5@28211|Alphaproteobacteria,4415M@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	negative chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2799101_14	215803.DB30_0833	2.083e-12	82.0	COG3291@1|root,COG3291@2|Bacteria,1PMFY@1224|Proteobacteria,42Y8D@68525|delta/epsilon subdivisions,2WUNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
REGS1_k127_2799101_3	521011.Mpal_0423	9.217e-171	592.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
REGS1_k127_2799101_12	946483.Cenrod_0604	2.23e-34	155.0	COG0515@1|root,COG2340@1|root,COG3227@1|root,COG3637@1|root,COG4733@1|root,COG0515@2|Bacteria,COG2340@2|Bacteria,COG3227@2|Bacteria,COG3637@2|Bacteria,COG4733@2|Bacteria,1N79H@1224|Proteobacteria	1224|Proteobacteria	KLT	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1566
REGS1_k127_2799101_17	1320556.AVBP01000001_gene4873	1.926e-06	63.0	COG1749@1|root,COG1749@2|Bacteria,1QWWE@1224|Proteobacteria,2TX6F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	N	Domain of unknown function (DUF4082)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082
REGS1_k127_2799101_5	243231.GSU0150	1.157e-155	497.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,43UK0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
REGS1_k127_2799101_8	398767.Glov_3150	1.456e-87	291.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,43RZ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
REGS1_k127_284394_2	1121918.ARWE01000001_gene2208	3.1e-139	453.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,PAS,PAS_3,PAS_9,Response_reg
REGS1_k127_284394_0	338966.Ppro_1456	8.943e-274	848.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,43S64@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_284394_4	443143.GM18_2018	1.821e-68	243.0	28IJW@1|root,2Z8KR@2|Bacteria,1R45I@1224|Proteobacteria,43035@68525|delta/epsilon subdivisions,2WV8Z@28221|Deltaproteobacteria,43V38@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_284394_1	443143.GM18_2739	3.063e-215	676.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria,43UX8@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	PLD-like domain	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
REGS1_k127_284394_3	760117.JN27_20210	1.093e-80	278.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria,472BA@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
REGS1_k127_2844369_24	243231.GSU1836	1.497e-61	213.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,43V1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
REGS1_k127_2844369_1	398767.Glov_1880	2.957e-313	959.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,43TAZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
REGS1_k127_2844369_35	1158318.ATXC01000001_gene1140	6.017e-40	168.0	COG3437@1|root,COG3437@2|Bacteria,2G5H0@200783|Aquificae	200783|Aquificae	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HD
REGS1_k127_2844369_19	443144.GM21_1942	1.093e-102	341.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,T2SSE_N
REGS1_k127_2844369_6	243231.GSU1609	1.6e-155	505.0	COG1538@1|root,COG1538@2|Bacteria,1MWQK@1224|Proteobacteria,42UQA@68525|delta/epsilon subdivisions,2WQXF@28221|Deltaproteobacteria,43TDQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_2844369_33	338966.Ppro_0923	2.266e-40	151.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WS9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_2844369_32	338966.Ppro_0924	2.199e-40	162.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_2844369_8	338966.Ppro_0926	2.088e-151	487.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,42N4J@68525|delta/epsilon subdivisions,2WIY7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_2844369_15	338966.Ppro_0927	6.01e-120	394.0	COG0304@1|root,COG0304@2|Bacteria,1RIQ4@1224|Proteobacteria,42SZC@68525|delta/epsilon subdivisions,2WPDY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM Beta-ketoacyl synthase	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
REGS1_k127_2844369_38	338966.Ppro_0928	3.501e-19	89.0	COG0236@1|root,COG0236@2|Bacteria,1P4UP@1224|Proteobacteria,432WS@68525|delta/epsilon subdivisions,2WYAG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
REGS1_k127_2844369_18	338966.Ppro_0929	1.085e-103	354.0	COG1020@1|root,COG1020@2|Bacteria,1NK69@1224|Proteobacteria,42Z6P@68525|delta/epsilon subdivisions,2WUP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	D-alanine [D-alanyl carrier protein] ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2844369_23	933262.AXAM01000001_gene381	1.372e-71	256.0	COG0644@1|root,COG0644@2|Bacteria,1QM8G@1224|Proteobacteria	1224|Proteobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
REGS1_k127_2844369_13	933262.AXAM01000001_gene412	1.902e-129	429.0	COG1032@1|root,COG1032@2|Bacteria,1R92G@1224|Proteobacteria,42RM5@68525|delta/epsilon subdivisions,2WNP2@28221|Deltaproteobacteria,2MNIA@213118|Desulfobacterales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_2844369_9	933262.AXAM01000001_gene380	2.478e-149	489.0	COG0318@1|root,COG0318@2|Bacteria,1NRID@1224|Proteobacteria,43CJB@68525|delta/epsilon subdivisions,2X7TP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
REGS1_k127_2844369_11	269799.Gmet_1705	4.738e-139	458.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42MVS@68525|delta/epsilon subdivisions,2WJKA@28221|Deltaproteobacteria,43TEP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_2844369_5	243231.GSU1222	2.45e-184	583.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42MY3@68525|delta/epsilon subdivisions,2WJEF@28221|Deltaproteobacteria,43TQX@69541|Desulfuromonadales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	ko:K04768	-	-	-	-	ko00000	-	-	-	Hist_deacetyl
REGS1_k127_2844369_21	316067.Geob_2916	1.185e-86	297.0	COG0457@1|root,COG0457@2|Bacteria	316067.Geob_2916|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2844369_12	269799.Gmet_1743	2.407e-134	433.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42YJC@68525|delta/epsilon subdivisions,2WTKU@28221|Deltaproteobacteria,43TDB@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
REGS1_k127_2844369_31	269799.Gmet_1747	7.271e-41	156.0	COG0745@1|root,COG0745@2|Bacteria,1N0WF@1224|Proteobacteria,42TTF@68525|delta/epsilon subdivisions,2WR69@28221|Deltaproteobacteria,43SMH@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_2844369_34	243231.GSU1233	5.12e-40	153.0	COG0622@1|root,COG0622@2|Bacteria,1NNW7@1224|Proteobacteria,42XHT@68525|delta/epsilon subdivisions,2WTG5@28221|Deltaproteobacteria,43VHS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
REGS1_k127_2844369_14	316067.Geob_2906	3.185e-121	396.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2WK7Z@28221|Deltaproteobacteria,43U31@69541|Desulfuromonadales	28221|Deltaproteobacteria	OU	TIGRFAM signal peptide peptidase SppA, 36K type	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
REGS1_k127_2844369_7	269799.Gmet_1235	1.489e-152	487.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,43UAB@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_2844369_10	443143.GM18_2521	1.469e-140	450.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
REGS1_k127_2844369_28	316067.Geob_3032	1.338e-50	184.0	2EB4E@1|root,33554@2|Bacteria,1NFIV@1224|Proteobacteria,42WN6@68525|delta/epsilon subdivisions,2WRA0@28221|Deltaproteobacteria,43SRW@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2844369_4	269799.Gmet_1295	3.093e-232	732.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,43S56@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
REGS1_k127_2844369_36	243231.GSU1324	1.965e-32	128.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42V9Q@68525|delta/epsilon subdivisions,2WRRT@28221|Deltaproteobacteria,43SRQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
REGS1_k127_2844369_22	316067.Geob_1922	8.428e-83	278.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,42SJF@68525|delta/epsilon subdivisions,2WP4X@28221|Deltaproteobacteria,43U8B@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_2844369_16	338966.Ppro_0405	6.456e-115	380.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,42S7F@68525|delta/epsilon subdivisions,2WK0P@28221|Deltaproteobacteria,43T7X@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_2844369_29	269799.Gmet_1429	1.683e-43	164.0	COG3065@1|root,COG3065@2|Bacteria,1MZ8C@1224|Proteobacteria,42TQE@68525|delta/epsilon subdivisions,2WQIC@28221|Deltaproteobacteria,43V95@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein Slp family	-	-	-	ko:K07285	-	-	-	-	ko00000	-	-	-	Slp
REGS1_k127_2844369_2	443143.GM18_2350	1.172e-293	934.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,42T02@68525|delta/epsilon subdivisions,2WPNU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	PFAM WD40 domain protein beta Propeller	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
REGS1_k127_2844369_0	316067.Geob_2657	0.0	1618.0	COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,42M43@68525|delta/epsilon subdivisions,2WKJD@28221|Deltaproteobacteria,43T8U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the aconitase IPM isomerase family	acnB	-	4.2.1.3,4.2.1.99	ko:K01682	ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173	R01324,R01325,R01900,R04425	RC00497,RC00498,RC00618,RC01153	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_2_N,Aconitase_B_N
REGS1_k127_2844369_17	443144.GM21_1979	8.058e-107	355.0	COG0705@1|root,COG0705@2|Bacteria,1N258@1224|Proteobacteria,42UB4@68525|delta/epsilon subdivisions,2WQJ3@28221|Deltaproteobacteria,43U5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
REGS1_k127_2844369_26	443144.GM21_2966	1.122e-54	194.0	COG0720@1|root,COG0720@2|Bacteria,1RI4P@1224|Proteobacteria,42TJ5@68525|delta/epsilon subdivisions,2WQ2Z@28221|Deltaproteobacteria,43UWB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM 6-pyruvoyl tetrahydropterin synthase and	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
REGS1_k127_2844369_20	243231.GSU1721	6.673e-89	300.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,42RT9@68525|delta/epsilon subdivisions,2WNJ0@28221|Deltaproteobacteria,43SFA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	iAF987.Gmet_1658	Fer4_14,Radical_SAM
REGS1_k127_2844369_3	269799.Gmet_1766	8.737e-244	758.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,43UJT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
REGS1_k127_2898921_22	269799.Gmet_2065	4.849e-05	48.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,43T69@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_10,Fer4_8
REGS1_k127_2898921_4	269799.Gmet_2257	8.371e-215	673.0	COG1143@1|root,COG2025@1|root,COG1143@2|Bacteria,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42MH7@68525|delta/epsilon subdivisions,2WK12@28221|Deltaproteobacteria,43TGU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	iAF987.Gmet_2257	ETF,ETF_alpha
REGS1_k127_2898921_6	316067.Geob_1807	8.157e-142	453.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42RMH@68525|delta/epsilon subdivisions,2WNKC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Electron transfer flavoprotein alpha beta-subunit	etfB-3	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
REGS1_k127_2898921_16	316067.Geob_2592	4.169e-59	214.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
REGS1_k127_2898921_7	269799.Gmet_0681	7.098e-141	454.0	COG0535@1|root,COG0535@2|Bacteria,1MWDC@1224|Proteobacteria,42MHB@68525|delta/epsilon subdivisions,2WIPH@28221|Deltaproteobacteria,43U2A@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	nifB	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Fer4_14,Nitro_FeMo-Co,Radical_SAM
REGS1_k127_2898921_17	338966.Ppro_1921	3.919e-27	116.0	2EA6Y@1|root,343BS@2|Bacteria,1P3AF@1224|Proteobacteria,431RE@68525|delta/epsilon subdivisions,2WWGD@28221|Deltaproteobacteria,43VKX@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2898921_8	243231.GSU2800	1.689e-130	422.0	COG1397@1|root,COG1397@2|Bacteria,1NTUR@1224|Proteobacteria,42NZI@68525|delta/epsilon subdivisions,2WIT8@28221|Deltaproteobacteria,43UJ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ADP-ribosylglycohydrolase	draG	-	3.2.2.24	ko:K05521	-	-	-	-	ko00000,ko01000	-	-	-	ADP_ribosyl_GH
REGS1_k127_2898921_2	243231.GSU0962	7.775e-297	922.0	COG4191@1|root,COG4564@1|root,COG4191@2|Bacteria,COG4564@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2WIUX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,dCache_1
REGS1_k127_2898921_18	1121396.KB893001_gene3961	1.371e-26	116.0	COG2165@1|root,COG2165@2|Bacteria,1QYWM@1224|Proteobacteria,43DBQ@68525|delta/epsilon subdivisions,2WVZ5@28221|Deltaproteobacteria,2MNW2@213118|Desulfobacterales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
REGS1_k127_2898921_9	269799.Gmet_1885	3.909e-116	377.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,43UAY@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
REGS1_k127_2898921_3	269799.Gmet_1886	1.175e-256	795.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,43T4H@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_2898921_20	1121918.ARWE01000001_gene2316	4.742e-10	66.0	COG4856@1|root,COG4856@2|Bacteria,1REEU@1224|Proteobacteria,42RY2@68525|delta/epsilon subdivisions,2WNZH@28221|Deltaproteobacteria,43SGW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
REGS1_k127_2898921_13	316067.Geob_3421	2.177e-81	278.0	COG1624@1|root,COG1624@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,43SDZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
REGS1_k127_2898921_11	269799.Gmet_1889	5.982e-104	344.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,43T3H@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Pterin binding enzyme	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
REGS1_k127_2898921_1	316067.Geob_3423	0.0	1018.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,43U9K@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
REGS1_k127_2898921_10	243231.GSU1810	6.272e-111	374.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,43U6A@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
REGS1_k127_2898921_12	909663.KI867150_gene487	1.242e-89	308.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,2MQC9@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
REGS1_k127_2898921_0	243231.GSU0500	0.0	1086.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,43UC8@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Elongation factor G C-terminus	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_2898921_14	269799.Gmet_3014	3.5e-76	262.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,43UNU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
REGS1_k127_2898921_15	316067.Geob_0760	7.552e-72	246.0	28HPC@1|root,2Z7XD@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
REGS1_k127_2898921_5	443144.GM21_3563	2.442e-165	562.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_332122_14	269799.Gmet_2866	6.449e-60	208.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,42TMU@68525|delta/epsilon subdivisions,2WQ67@28221|Deltaproteobacteria,43UYA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
REGS1_k127_332122_13	443143.GM18_0674	3.986e-70	241.0	COG4752@1|root,COG4752@2|Bacteria,1RJ2G@1224|Proteobacteria,42SXX@68525|delta/epsilon subdivisions,2WP1I@28221|Deltaproteobacteria,43UKZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	SAM-dependent RNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrn_RNA_4
REGS1_k127_332122_9	443143.GM18_0673	1.026e-92	309.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,43U24@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
REGS1_k127_332122_16	243231.GSU0645	4.137e-51	186.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,42TGI@68525|delta/epsilon subdivisions,2WQJU@28221|Deltaproteobacteria,43VFS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
REGS1_k127_332122_21	316067.Geob_1488	3.704e-34	134.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria,43VJ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
REGS1_k127_332122_20	269799.Gmet_2871	7.132e-39	147.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,42V30@68525|delta/epsilon subdivisions,2WRH7@28221|Deltaproteobacteria,43VM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
REGS1_k127_332122_2	269799.Gmet_2872	1.161e-230	721.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,43UI7@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
REGS1_k127_332122_5	1121918.ARWE01000001_gene2493	7.745e-113	391.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	HEAT_2,HEAT_PBS,NACHT,Peptidase_M9,Peptidase_M9_N
REGS1_k127_332122_8	1121918.ARWE01000001_gene2494	6.425e-106	357.0	COG2206@1|root,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
REGS1_k127_332122_0	1121918.ARWE01000001_gene3179	4.309e-287	900.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE,T2SSE_N
REGS1_k127_332122_3	338966.Ppro_2848	1.721e-214	672.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42N2K@68525|delta/epsilon subdivisions,2WJ5D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	DAO,FAD_binding_2,GIDA,HI0933_like,Pyr_redox_2
REGS1_k127_332122_24	261292.Nit79A3_0013	5.491e-19	91.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.4.1.21	ko:K00703,ko:K07082	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	AAA_12,DUF559,PGA_cap,WG_beta_rep
REGS1_k127_332122_6	269799.Gmet_0188	1.373e-107	361.0	COG1234@1|root,COG1234@2|Bacteria,1PPRD@1224|Proteobacteria,42YJB@68525|delta/epsilon subdivisions,2WTTA@28221|Deltaproteobacteria,43TIZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
REGS1_k127_332122_19	443144.GM21_2074	6.356e-39	157.0	29AH1@1|root,2ZXH8@2|Bacteria,1P6W9@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_332122_18	338966.Ppro_2143	1.009e-42	160.0	COG1371@1|root,COG1371@2|Bacteria,1NMZF@1224|Proteobacteria,42X9A@68525|delta/epsilon subdivisions,2WSP3@28221|Deltaproteobacteria,43V4V@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
REGS1_k127_332122_1	338966.Ppro_2142	1.616e-263	822.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,43SZD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
REGS1_k127_332122_4	243231.GSU1728	1.658e-175	555.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,42N7U@68525|delta/epsilon subdivisions,2WJ81@28221|Deltaproteobacteria,43T1P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_332122_28	1382359.JIAL01000001_gene810	0.0001282	51.0	2EGII@1|root,33AAP@2|Bacteria,3Y5ST@57723|Acidobacteria,2JK57@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_332122_11	316067.Geob_0059	4.665e-77	279.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
REGS1_k127_332122_10	767817.Desgi_1425	2.511e-89	308.0	COG2271@1|root,COG2271@2|Bacteria,1UIF2@1239|Firmicutes,25EKE@186801|Clostridia,265TF@186807|Peptococcaceae	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_332122_15	404380.Gbem_0105	2.85e-56	200.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
REGS1_k127_332122_7	316067.Geob_3029	1.929e-107	358.0	COG1413@1|root,COG2804@1|root,COG1413@2|Bacteria,COG2804@2|Bacteria,1NXSX@1224|Proteobacteria,430TC@68525|delta/epsilon subdivisions,2WW30@28221|Deltaproteobacteria,43VAV@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	T2SSE_N
REGS1_k127_332122_12	1499967.BAYZ01000016_gene6507	3.008e-76	267.0	COG1226@1|root,COG1226@2|Bacteria,2NP71@2323|unclassified Bacteria	2|Bacteria	U	Ion channel	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
REGS1_k127_332122_22	1121918.ARWE01000001_gene2844	5.893e-28	121.0	COG0328@1|root,COG0328@2|Bacteria,1RI5K@1224|Proteobacteria,42T01@68525|delta/epsilon subdivisions,2WPRB@28221|Deltaproteobacteria,43UW1@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	RNase H	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H
REGS1_k127_332122_17	1121918.ARWE01000001_gene316	2.607e-46	167.0	COG2026@1|root,COG2026@2|Bacteria,1QY8F@1224|Proteobacteria,43CA6@68525|delta/epsilon subdivisions,2X7KN@28221|Deltaproteobacteria,43SS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_341932_2	159087.Daro_2753	5.253e-53	189.0	COG3263@1|root,COG3263@2|Bacteria	2|Bacteria	P	cell volume homeostasis	cvrA	-	-	ko:K03316,ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36,2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
REGS1_k127_341932_1	398767.Glov_1394	8.436e-156	505.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,42NIF@68525|delta/epsilon subdivisions,2WJST@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	CBS domain containing protein	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
REGS1_k127_341932_3	1125863.JAFN01000001_gene788	3.194e-25	110.0	COG0727@1|root,COG0727@2|Bacteria,1N9W2@1224|Proteobacteria,42VKK@68525|delta/epsilon subdivisions,2WRG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
REGS1_k127_341932_0	316067.Geob_0832	0.0	1203.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,43T0F@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
REGS1_k127_3473517_7	1232410.KI421426_gene1365	1.407e-73	255.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,42R6I@68525|delta/epsilon subdivisions,2WN1K@28221|Deltaproteobacteria,43T11@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	MlaA lipoprotein	-	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
REGS1_k127_3473517_1	398767.Glov_1638	4.879e-237	749.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42P9Y@68525|delta/epsilon subdivisions,2WM6A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II protein E domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,T2SSE,T2SSE_N
REGS1_k127_3473517_4	909663.KI867149_gene3364	3.12e-177	567.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,2MQT1@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
REGS1_k127_3473517_5	338966.Ppro_1563	6.543e-83	284.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	2.4.1.266	ko:K09118,ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Usp
REGS1_k127_3473517_0	338966.Ppro_1564	0.0	1233.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8,3.6.3.9	ko:K01537,ko:K01539	ko04022,ko04024,ko04260,ko04261,ko04911,ko04918,ko04919,ko04925,ko04960,ko04961,ko04964,ko04970,ko04971,ko04972,ko04973,ko04974,ko04976,ko04978,map04022,map04024,map04260,map04261,map04911,map04918,map04919,map04925,map04960,map04961,map04964,map04970,map04971,map04972,map04973,map04974,map04976,map04978	-	-	-	ko00000,ko00001,ko01000,ko04147	3.A.3.1,3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,PTS_EIIA_2
REGS1_k127_3473517_10	1122236.KB905146_gene1893	5.33e-10	64.0	2EGHT@1|root,33A9W@2|Bacteria,1NHZD@1224|Proteobacteria,2VXKV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3473517_3	365044.Pnap_3704	1.908e-223	705.0	COG2831@1|root,COG2831@2|Bacteria,1MWEC@1224|Proteobacteria,2VJXF@28216|Betaproteobacteria,4ADI9@80864|Comamonadaceae	28216|Betaproteobacteria	U	Haemolysin secretion/activation protein ShlB/FhaC/HecB	-	-	-	-	-	-	-	-	-	-	-	-	POTRA_2,ShlB
REGS1_k127_3473517_2	365044.Pnap_3705	4.072e-224	743.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,1MXIP@1224|Proteobacteria,2VJ6Y@28216|Betaproteobacteria,4A9P1@80864|Comamonadaceae	28216|Betaproteobacteria	U	TIGRFAM filamentous haemagglutinin family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	ESPR,Glug,Haemagg_act
REGS1_k127_3473517_6	365044.Pnap_3706	6.172e-75	261.0	COG1376@1|root,COG1376@2|Bacteria,1R7VK@1224|Proteobacteria,2VRX0@28216|Betaproteobacteria,4AE5A@80864|Comamonadaceae	28216|Betaproteobacteria	S	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3473517_8	118005.AWNK01000007_gene731	1.071e-67	237.0	2DT2H@1|root,33IDP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2959
REGS1_k127_3473517_9	443143.GM18_2737	2.401e-14	73.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3475496_5	443144.GM21_2686	1.825e-65	241.0	COG0745@1|root,COG0745@2|Bacteria,1NER5@1224|Proteobacteria,42VHC@68525|delta/epsilon subdivisions,2WSGQ@28221|Deltaproteobacteria,43UMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_3475496_0	398767.Glov_2538	0.0	1556.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
REGS1_k127_3475496_4	243231.GSU2043	1.283e-112	369.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,43TK2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
REGS1_k127_3475496_3	443144.GM21_2683	1.017e-135	447.0	COG4191@1|root,COG4191@2|Bacteria,1R9AK@1224|Proteobacteria,42Q2G@68525|delta/epsilon subdivisions,2WM8Y@28221|Deltaproteobacteria,43RXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_3475496_2	316067.Geob_3079	4.469e-188	597.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_3475496_1	404380.Gbem_2345	3.036e-316	1032.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WJYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
REGS1_k127_3475496_8	316067.Geob_3076	1.93e-22	104.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	fimU	-	-	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.15.2	-	-	N_methyl
REGS1_k127_3475496_9	243231.GSU2036	1.506e-15	81.0	COG4967@1|root,COG4967@2|Bacteria,1NHY3@1224|Proteobacteria,42WZH@68525|delta/epsilon subdivisions,2WSKR@28221|Deltaproteobacteria,43VUB@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pfam:N_methyl_2	pilV-2	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
REGS1_k127_3475496_6	243231.GSU2035	1.911e-64	237.0	COG4968@1|root,COG4968@2|Bacteria,1REDT@1224|Proteobacteria,42RY5@68525|delta/epsilon subdivisions,2WNPG@28221|Deltaproteobacteria,43V26@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilW-2	-	-	-	-	-	-	-	-	-	-	-	N_methyl,PilW
REGS1_k127_3475496_7	404380.Gbem_1540	1.338e-41	162.0	2E6Z6@1|root,331IC@2|Bacteria,1NY0D@1224|Proteobacteria,430VK@68525|delta/epsilon subdivisions,2WVKD@28221|Deltaproteobacteria,43VJN@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	pilX-2	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3475496_11	338966.Ppro_2849	2.178e-06	49.0	COG4447@1|root,COG4447@2|Bacteria,1PFCA@1224|Proteobacteria,42WUH@68525|delta/epsilon subdivisions,2WT3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
REGS1_k127_3541035_4	243231.GSU2502	3.345e-189	613.0	COG0421@1|root,COG0421@2|Bacteria,1QX98@1224|Proteobacteria,43C2D@68525|delta/epsilon subdivisions,2X7CZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_3541035_11	335543.Sfum_1739	5.991e-147	495.0	COG1492@1|root,COG1492@2|Bacteria,1MUFY@1224|Proteobacteria,42M9K@68525|delta/epsilon subdivisions,2WJ22@28221|Deltaproteobacteria,2MR2H@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,Aminotran_1_2,CbiA,GATase_3,TP_methylase
REGS1_k127_3541035_12	316067.Geob_0036	2.849e-137	447.0	COG2073@1|root,COG2073@2|Bacteria,1MWE6@1224|Proteobacteria,42Q6F@68525|delta/epsilon subdivisions,2WJG4@28221|Deltaproteobacteria,43S0I@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Cobalamin biosynthesis central region	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid
REGS1_k127_3541035_31	404380.Gbem_3331	1.108e-63	228.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	pstS	-	-	ko:K02038,ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1,PBP_like_2
REGS1_k127_3541035_46	243231.GSU0583	1.381e-29	136.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions,2WM8F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Chemotaxis sensory transducer	mcp64H-1	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_4,dCache_1
REGS1_k127_3541035_13	316067.Geob_0034	5.32e-126	407.0	COG2875@1|root,COG2875@2|Bacteria,1MVYY@1224|Proteobacteria,42P88@68525|delta/epsilon subdivisions,2WMR1@28221|Deltaproteobacteria,43T6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cbiF	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,TP_methylase
REGS1_k127_3541035_20	269799.Gmet_0482	1.726e-108	355.0	COG2243@1|root,COG2243@2|Bacteria,1MV3G@1224|Proteobacteria,42MGC@68525|delta/epsilon subdivisions,2WM51@28221|Deltaproteobacteria,43SH5@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cbiL	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0482	TP_methylase
REGS1_k127_3541035_2	269799.Gmet_0481	5.744e-223	696.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,1MVJX@1224|Proteobacteria,42MEZ@68525|delta/epsilon subdivisions,2WIUW@28221|Deltaproteobacteria,43SWQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase	cbiET	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Cons_hypoth95,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
REGS1_k127_3541035_10	443143.GM18_0545	2.162e-152	489.0	COG1903@1|root,COG1903@2|Bacteria,1MXU3@1224|Proteobacteria,42N2R@68525|delta/epsilon subdivisions,2WJF4@28221|Deltaproteobacteria,43RZC@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
REGS1_k127_3541035_24	269799.Gmet_0477	2.895e-92	308.0	COG2082@1|root,COG2082@2|Bacteria,1MX1E@1224|Proteobacteria,42RIY@68525|delta/epsilon subdivisions,2WN0J@28221|Deltaproteobacteria,43TI6@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM Precorrin-8X methylmutase CbiC CobH	cbiC	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
REGS1_k127_3541035_33	338966.Ppro_1299	2.778e-57	201.0	COG2138@1|root,COG2138@2|Bacteria,1QXPH@1224|Proteobacteria,42XIT@68525|delta/epsilon subdivisions,2WSVI@28221|Deltaproteobacteria,43UWN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM cobalamin (vitamin B12) biosynthesis CbiX protein	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	2Fe-2S_thioredx,CbiX
REGS1_k127_3541035_14	316067.Geob_0547	1.556e-125	407.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,42R39@68525|delta/epsilon subdivisions,2WN10@28221|Deltaproteobacteria,43SJ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
REGS1_k127_3541035_26	269799.Gmet_0474	3.145e-85	290.0	COG0619@1|root,COG0619@2|Bacteria,1R4KM@1224|Proteobacteria,42WF5@68525|delta/epsilon subdivisions,2WSAH@28221|Deltaproteobacteria,43ST2@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
REGS1_k127_3541035_44	443143.GM18_4237	2.139e-32	128.0	2EQ3B@1|root,33HPN@2|Bacteria,1P6DF@1224|Proteobacteria,433K1@68525|delta/epsilon subdivisions,2WY80@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	-
REGS1_k127_3541035_18	316067.Geob_0544	2.662e-112	367.0	COG0310@1|root,COG0310@2|Bacteria,1NTQK@1224|Proteobacteria,42SA9@68525|delta/epsilon subdivisions,2WNVZ@28221|Deltaproteobacteria,43SN0@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
REGS1_k127_3541035_3	243231.GSU3006	1.696e-198	629.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,42M8T@68525|delta/epsilon subdivisions,2WIXE@28221|Deltaproteobacteria,43T2Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0470	CPT,CbiA,GATase_3
REGS1_k127_3541035_25	398767.Glov_3084	4.208e-87	291.0	COG0406@1|root,COG0406@2|Bacteria,1RHAT@1224|Proteobacteria,42SUD@68525|delta/epsilon subdivisions,2WP5H@28221|Deltaproteobacteria,43UKX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
REGS1_k127_3541035_27	269799.Gmet_0468	3.767e-78	268.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,42TXY@68525|delta/epsilon subdivisions,2WQ4J@28221|Deltaproteobacteria,43TKG@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
REGS1_k127_3541035_6	443144.GM21_3897	7.321e-160	510.0	COG2038@1|root,COG2038@2|Bacteria,1MVAM@1224|Proteobacteria,42M3Z@68525|delta/epsilon subdivisions,2WJIR@28221|Deltaproteobacteria,43T4Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
REGS1_k127_3541035_30	316067.Geob_0538	1.126e-66	233.0	COG2087@1|root,COG2087@2|Bacteria,1RH0A@1224|Proteobacteria,42TMF@68525|delta/epsilon subdivisions,2WQNM@28221|Deltaproteobacteria,43V0A@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
REGS1_k127_3541035_38	443144.GM21_1930	3.095e-39	150.0	2EQD3@1|root,33HZ5@2|Bacteria,1P9PI@1224|Proteobacteria,433DW@68525|delta/epsilon subdivisions,2WX7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3541035_5	269799.Gmet_0024	2.468e-186	586.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,42MU4@68525|delta/epsilon subdivisions,2WJ8Y@28221|Deltaproteobacteria,43TP3@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	NeuB family	aroG-1	-	2.5.1.54,5.4.99.5	ko:K03856,ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R01715,R01826	RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,DAHP_synth_1
REGS1_k127_3541035_49	316067.Geob_0402	8.093e-23	104.0	COG2952@1|root,COG2952@2|Bacteria,1P5SW@1224|Proteobacteria,432F2@68525|delta/epsilon subdivisions,2WXGJ@28221|Deltaproteobacteria,43VR0@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF507)	-	-	-	-	-	-	-	-	-	-	-	-	DUF507
REGS1_k127_3541035_42	316067.Geob_0401	8.694e-35	134.0	COG2952@1|root,COG2952@2|Bacteria,1NKWU@1224|Proteobacteria,42XJT@68525|delta/epsilon subdivisions,2WSNN@28221|Deltaproteobacteria,43SST@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF507)	-	-	-	-	-	-	-	-	-	-	-	-	DUF507
REGS1_k127_3541035_16	243231.GSU0030	3.939e-121	401.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,43SZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_3541035_15	243231.GSU0029	2.667e-124	402.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42QTI@68525|delta/epsilon subdivisions,2WMRH@28221|Deltaproteobacteria,43SYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.3	ko:K13566	ko00250,map00250	-	R00269,R00348	RC00010	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
REGS1_k127_3541035_19	316067.Geob_1102	1.453e-110	361.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2WNQ4@28221|Deltaproteobacteria,43UJY@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	aglX	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
REGS1_k127_3541035_35	269799.Gmet_3538	6.078e-56	198.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,43UY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
REGS1_k127_3541035_48	404380.Gbem_3512	1.385e-23	109.0	COG0810@1|root,COG0810@2|Bacteria,1Q9SX@1224|Proteobacteria,42UPJ@68525|delta/epsilon subdivisions,2WQZ3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2
REGS1_k127_3541035_9	316067.Geob_1099	4.117e-157	507.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,43UDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
REGS1_k127_3541035_36	243231.GSU0024	8.154e-42	162.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,42R5H@68525|delta/epsilon subdivisions,2WNZS@28221|Deltaproteobacteria,43UVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM OmpA MotB domain protein	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
REGS1_k127_3541035_29	316067.Geob_1097	1.387e-72	254.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,42P32@68525|delta/epsilon subdivisions,2WM9Q@28221|Deltaproteobacteria,43URZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
REGS1_k127_3541035_51	243231.GSU0022	9.382e-21	94.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_3541035_8	269799.Gmet_3544	2.217e-157	500.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,43TGD@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
REGS1_k127_3541035_17	243231.GSU0014	1.243e-120	393.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,43T7R@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	heat shock protein DnaJ domain protein	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
REGS1_k127_3541035_54	1128427.KB904821_gene859	2.104e-08	63.0	COG1669@1|root,COG1669@2|Bacteria,1G88F@1117|Cyanobacteria,1HC46@1150|Oscillatoriales	1117|Cyanobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
REGS1_k127_3541035_58	518766.Rmar_1765	0.0002323	49.0	COG2361@1|root,COG2361@2|Bacteria,4NV8D@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
REGS1_k127_3541035_50	1158338.JNLJ01000001_gene661	4.658e-21	97.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_3541035_55	123214.PERMA_0472	3.1e-08	57.0	291WM@1|root,2ZPG9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CcdA
REGS1_k127_3541035_34	443143.GM18_1308	1.878e-56	198.0	COG4226@1|root,COG4226@2|Bacteria,1MZYR@1224|Proteobacteria,42WDN@68525|delta/epsilon subdivisions,2WRW3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
REGS1_k127_3541035_37	398767.Glov_0060	7.861e-40	149.0	2CT64@1|root,32SSN@2|Bacteria,1N7H4@1224|Proteobacteria,42WK1@68525|delta/epsilon subdivisions,2WRS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
REGS1_k127_3541035_60	743836.AYNA01000040_gene783	0.0007058	43.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2TRZ1@28211|Alphaproteobacteria,36XPG@31993|Methylocystaceae	28211|Alphaproteobacteria	O	DnaJ central domain	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
REGS1_k127_3541035_45	1189619.pgond44_14848	4.17e-32	135.0	COG3755@1|root,COG3755@2|Bacteria,4NTGW@976|Bacteroidetes,1I6JA@117743|Flavobacteriia	976|Bacteroidetes	S	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
REGS1_k127_3541035_43	443143.GM18_4373	1.943e-34	133.0	COG3093@1|root,COG3093@2|Bacteria,1R0AM@1224|Proteobacteria,43CT1@68525|delta/epsilon subdivisions,2X80J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_3541035_21	316067.Geob_3713	8.257e-107	358.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,43TFD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
REGS1_k127_3541035_0	398767.Glov_0981	0.0	1535.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
REGS1_k127_3541035_28	243231.GSU1043	1.633e-77	272.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,MASE3,PAS_3,PAS_4,PAS_9,dCache_1
REGS1_k127_3541035_40	243231.GSU3495	1.049e-36	141.0	2E7B6@1|root,331UK@2|Bacteria,1N80C@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3541035_1	443143.GM18_0097	0.0	1044.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria	1224|Proteobacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_3541035_7	443143.GM18_2098	7.548e-158	520.0	COG2770@1|root,COG4191@1|root,COG2770@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,dCache_1
REGS1_k127_3541035_23	443144.GM21_3285	4.797e-96	335.0	COG0745@1|root,COG2208@1|root,COG0745@2|Bacteria,COG2208@2|Bacteria,1NWAF@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator, receiver	-	-	3.1.4.52	ko:K13246	ko05111,map05111	-	R08991	RC00296	ko00000,ko00001,ko01000	-	-	-	EAL,GGDEF,GerE,HD,HTH_18,HWE_HK,HisKA_2,PAS,PAS_3,PAS_9,Response_reg,SpoIIE,Trans_reg_C
REGS1_k127_3541035_39	404380.Gbem_2535	4.286e-37	147.0	COG0745@1|root,COG0745@2|Bacteria,1RD7E@1224|Proteobacteria,42T3B@68525|delta/epsilon subdivisions,2WP8H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
REGS1_k127_3541035_22	857087.Metme_2403	1.966e-98	357.0	COG0642@1|root,COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1NRP8@1224|Proteobacteria,1SKTW@1236|Gammaproteobacteria,1XEIX@135618|Methylococcales	135618|Methylococcales	T	Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,PAS_9,Response_reg
REGS1_k127_3541035_32	296591.Bpro_0151	1.045e-58	229.0	COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG4251@1|root,COG5000@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,2WHF7@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS_4,dCache_1
REGS1_k127_3541035_52	1499967.BAYZ01000009_gene5240	1.514e-10	63.0	COG0745@1|root,COG4251@1|root,COG0745@2|Bacteria,COG4251@2|Bacteria,2NPB3@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF,GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_3541035_59	521011.Mpal_1514	0.0003759	47.0	COG0642@1|root,COG0784@1|root,arCOG04001@1|root,arCOG02333@2157|Archaea,arCOG04001@2157|Archaea,arCOG06193@2157|Archaea	2157|Archaea	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	BAT,GAF_2,HATPase_c,HTH_10,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_3541035_53	1123517.JOMR01000001_gene1585	1.67e-10	64.0	COG3221@1|root,COG3221@2|Bacteria,1R4SK@1224|Proteobacteria,1RR7M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type phosphate phosphonate transport system periplasmic component	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_3607330_3	316067.Geob_3164	2.295e-07	54.0	2AIHE@1|root,318Z9@2|Bacteria,1NWQ1@1224|Proteobacteria,42ZTQ@68525|delta/epsilon subdivisions,2WV9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3607330_2	159450.NH14_24075	7.97e-08	61.0	COG4380@1|root,COG4380@2|Bacteria,1R3WM@1224|Proteobacteria,2VQ6M@28216|Betaproteobacteria,1K28J@119060|Burkholderiaceae	28216|Betaproteobacteria	S	lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	DUF799
REGS1_k127_3607330_1	316067.Geob_3162	1.455e-82	289.0	2EUMZ@1|root,33N3U@2|Bacteria,1NUNW@1224|Proteobacteria,42ZFD@68525|delta/epsilon subdivisions,2WV00@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3607330_0	316067.Geob_3161	2.804e-159	529.0	COG0760@1|root,COG0760@2|Bacteria,1NQ2Y@1224|Proteobacteria,42XX8@68525|delta/epsilon subdivisions,2WSSQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_2
REGS1_k127_36485_7	398767.Glov_0101	2.083e-62	216.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
REGS1_k127_36485_4	443144.GM21_3762	5.026e-104	344.0	COG1073@1|root,COG1765@1|root,COG1073@2|Bacteria,COG1765@2|Bacteria,1N2BT@1224|Proteobacteria,43CTG@68525|delta/epsilon subdivisions,2X810@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	ko:K06889,ko:K07397	-	-	-	-	ko00000	-	-	-	Hydrolase_4,OsmC
REGS1_k127_36485_2	269799.Gmet_3009	7.167e-132	427.0	COG0177@1|root,COG0177@2|Bacteria,1RAK3@1224|Proteobacteria,42M4V@68525|delta/epsilon subdivisions,2WPRX@28221|Deltaproteobacteria,43T7W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Protein of unknown function (DUF2400)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2400
REGS1_k127_36485_8	243231.GSU0525	8.097e-59	208.0	COG1490@1|root,COG1490@2|Bacteria,1RGTV@1224|Proteobacteria,42SMU@68525|delta/epsilon subdivisions,2WP4P@28221|Deltaproteobacteria,43UNI@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
REGS1_k127_36485_11	443144.GM21_2635	8.308e-17	82.0	2EQIW@1|root,33I4X@2|Bacteria,1P5T0@1224|Proteobacteria,432D5@68525|delta/epsilon subdivisions,2WX86@28221|Deltaproteobacteria,43VTU@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_36485_3	243231.GSU0529	3.292e-128	417.0	COG0648@1|root,COG0648@2|Bacteria,1MX4Y@1224|Proteobacteria,42MYE@68525|delta/epsilon subdivisions,2WJC7@28221|Deltaproteobacteria,43T52@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
REGS1_k127_36485_6	316067.Geob_1398	2.419e-63	220.0	COG0537@1|root,COG0537@2|Bacteria,1MZVD@1224|Proteobacteria,42TMC@68525|delta/epsilon subdivisions,2WNCU@28221|Deltaproteobacteria,43SHK@69541|Desulfuromonadales	28221|Deltaproteobacteria	FG	PFAM histidine triad (HIT) protein	-	-	-	-	-	-	-	-	-	-	-	-	HIT
REGS1_k127_36485_1	243231.GSU0531	5.75e-163	517.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,42MRX@68525|delta/epsilon subdivisions,2WMIV@28221|Deltaproteobacteria,43U70@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
REGS1_k127_36485_10	269799.Gmet_2991	8.459e-29	116.0	28VPS@1|root,2ZHRQ@2|Bacteria,1PAIZ@1224|Proteobacteria,4335G@68525|delta/epsilon subdivisions,2WXW7@28221|Deltaproteobacteria,43VY5@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_36485_5	404380.Gbem_0360	4.032e-66	228.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,42V63@68525|delta/epsilon subdivisions,2WQCH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TIGRFAM transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
REGS1_k127_36485_0	398767.Glov_3416	4.131e-310	956.0	COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42NT5@68525|delta/epsilon subdivisions,2WIWR@28221|Deltaproteobacteria,43W00@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	alkK	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
REGS1_k127_36485_9	439235.Dalk_5269	4.479e-42	173.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1R09K@1224|Proteobacteria	1224|Proteobacteria	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_2
REGS1_k127_381304_12	243231.GSU1139	1.35e-149	475.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,43TMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
REGS1_k127_381304_22	696369.KI912183_gene517	3.16e-95	318.0	COG1692@1|root,COG1692@2|Bacteria,1TR9P@1239|Firmicutes,24967@186801|Clostridia,2604A@186807|Peptococcaceae	186801|Clostridia	S	TIGRFAM metallophosphoesterase, MG_246 BB_0505 family	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
REGS1_k127_381304_6	243231.GSU1137	2.826e-258	804.0	COG1418@1|root,COG1418@2|Bacteria,1P7YA@1224|Proteobacteria,42KZ8@68525|delta/epsilon subdivisions,2WJG1@28221|Deltaproteobacteria,43TAK@69541|Desulfuromonadales	28221|Deltaproteobacteria	A	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
REGS1_k127_381304_30	404380.Gbem_0967	5.225e-41	160.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,42U47@68525|delta/epsilon subdivisions,2WQXE@28221|Deltaproteobacteria,43UVW@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
REGS1_k127_381304_38	243231.GSU1134	1.659e-13	74.0	COG3027@1|root,COG3027@2|Bacteria,1PBAE@1224|Proteobacteria,43318@68525|delta/epsilon subdivisions,2WYCU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
REGS1_k127_381304_11	243231.GSU1132	1.993e-150	484.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,43TJM@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
REGS1_k127_381304_32	443143.GM18_0862	1.295e-32	130.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Robl_LC7
REGS1_k127_381304_1	269799.Gmet_1174	0.0	1162.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,43T01@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
REGS1_k127_381304_3	316067.Geob_2313	1.497e-291	929.0	COG2982@1|root,COG2982@2|Bacteria,1QA6E@1224|Proteobacteria,42URI@68525|delta/epsilon subdivisions,2WQ69@28221|Deltaproteobacteria,43U4E@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA,AsmA_2,DUF3971,DUF748
REGS1_k127_381304_34	316067.Geob_1623	3.901e-25	107.0	COG2221@1|root,COG2221@2|Bacteria,1QXPA@1224|Proteobacteria,42X12@68525|delta/epsilon subdivisions,2X7FG@28221|Deltaproteobacteria,43VTB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	frx-2	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1033	Fer4
REGS1_k127_381304_24	243231.GSU2710	4.72e-79	281.0	2AKQ6@1|root,2ZAYQ@2|Bacteria,1R429@1224|Proteobacteria,42NWN@68525|delta/epsilon subdivisions,2WMKI@28221|Deltaproteobacteria,43V14@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM MJ0042 family finger-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
REGS1_k127_381304_23	269799.Gmet_1030	1.825e-84	289.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_381304_15	316067.Geob_1627	1.448e-123	408.0	COG0303@1|root,COG0303@2|Bacteria,1MVD5@1224|Proteobacteria,42MZZ@68525|delta/epsilon subdivisions,2WIQI@28221|Deltaproteobacteria,43THW@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	MoeA domain protein domain I and II	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
REGS1_k127_381304_37	485915.Dret_0931	8.049e-16	83.0	arCOG09455@1|root,2ZPCS@2|Bacteria,1NPCM@1224|Proteobacteria,42XA8@68525|delta/epsilon subdivisions,2WT3H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_381304_7	316067.Geob_2765	2.921e-208	653.0	COG3635@1|root,COG3635@2|Bacteria,1R4TM@1224|Proteobacteria,42NCT@68525|delta/epsilon subdivisions,2WKEG@28221|Deltaproteobacteria,43SUK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Proposed homoserine kinase	apgM	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
REGS1_k127_381304_18	269799.Gmet_1427	7.013e-116	381.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,43TES@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	integrase domain protein SAM domain protein	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_381304_0	316067.Geob_2763	0.0	1261.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,43SYQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
REGS1_k127_381304_41	338963.Pcar_2061	8.203e-05	51.0	COG2340@1|root,COG2340@2|Bacteria,1NJB9@1224|Proteobacteria,42Y4H@68525|delta/epsilon subdivisions,2WSKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_381304_36	338963.Pcar_2060	3.174e-20	97.0	COG5430@1|root,COG5430@2|Bacteria	2|Bacteria	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
REGS1_k127_381304_25	338963.Pcar_2058	2.94e-69	243.0	COG3121@1|root,COG3121@2|Bacteria	2|Bacteria	NU	pilus organization	-	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
REGS1_k127_381304_8	338963.Pcar_2057	4.989e-178	587.0	COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,42WF9@68525|delta/epsilon subdivisions,2WRD4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Outer membrane usher protein	csuD	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	Usher
REGS1_k127_381304_33	338963.Pcar_2056	6.753e-28	120.0	COG5430@1|root,COG5430@2|Bacteria,1Q657@1224|Proteobacteria,432EY@68525|delta/epsilon subdivisions,2WYB4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
REGS1_k127_381304_28	243231.GSU1821	1.318e-42	158.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,43SVG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
REGS1_k127_381304_9	243231.GSU1821	1.057e-158	512.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,43SVG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
REGS1_k127_381304_4	635013.TherJR_1489	8.162e-267	847.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,260PA@186807|Peptococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
REGS1_k127_381304_14	243231.GSU2620	2.634e-130	424.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria,43SUY@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
REGS1_k127_381304_13	316067.Geob_3453	1.035e-143	464.0	COG2385@1|root,COG2385@2|Bacteria,1RGJS@1224|Proteobacteria,42RZE@68525|delta/epsilon subdivisions,2WNH8@28221|Deltaproteobacteria,43TQU@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM Stage II sporulation	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
REGS1_k127_381304_5	316067.Geob_3454	1.858e-260	820.0	COG2203@1|root,COG2206@1|root,COG3850@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria,COG3850@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2WP5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HD_5
REGS1_k127_381304_19	243231.GSU2623	4.372e-111	370.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,42M3F@68525|delta/epsilon subdivisions,2WJ32@28221|Deltaproteobacteria,43UBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Oligopeptide/dipeptide transporter, C-terminal region	oppD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
REGS1_k127_381304_17	316067.Geob_3456	5.695e-120	393.0	COG4608@1|root,COG4608@2|Bacteria,1NU4K@1224|Proteobacteria,42TDH@68525|delta/epsilon subdivisions,2WIQT@28221|Deltaproteobacteria,43S3N@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	dppF	-	-	ko:K02032,ko:K10823,ko:K12372	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00324,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
REGS1_k127_381304_2	243231.GSU1827	2.964e-300	925.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,43TWZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_381304_31	269799.Gmet_1955	2.161e-38	147.0	COG1605@1|root,COG1605@2|Bacteria,1Q1RX@1224|Proteobacteria,42U9H@68525|delta/epsilon subdivisions,2WQ7P@28221|Deltaproteobacteria,43SMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Chorismate mutase type II	-	-	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
REGS1_k127_381304_35	316067.Geob_2841	1.011e-24	104.0	COG2876@1|root,COG2876@2|Bacteria,1P3XZ@1224|Proteobacteria,43197@68525|delta/epsilon subdivisions,2WWVF@28221|Deltaproteobacteria,43VDB@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	3-deoxy-7-phosphoheptulonate synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_381304_29	404380.Gbem_3352	3.248e-41	156.0	2DDVI@1|root,2ZJFM@2|Bacteria,1P9PK@1224|Proteobacteria,433MV@68525|delta/epsilon subdivisions,2WXBY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_381304_10	269799.Gmet_1616	2.464e-156	501.0	COG0857@1|root,COG0857@2|Bacteria	2|Bacteria	C	belongs to the CobB CobQ family	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
REGS1_k127_381304_26	316067.Geob_1682	7.01e-63	240.0	COG3005@1|root,COG3005@2|Bacteria	2|Bacteria	C	denitrification pathway	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7,Multi-haem_cyto
REGS1_k127_381304_27	243231.GSU0076	1.922e-53	194.0	2EIFC@1|root,33C6Q@2|Bacteria,1NX12@1224|Proteobacteria,43080@68525|delta/epsilon subdivisions,2WVC5@28221|Deltaproteobacteria,43V28@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_381304_16	338966.Ppro_3201	3.617e-120	392.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,43TW9@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
REGS1_k127_381304_20	243231.GSU0825	1.64e-104	342.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
REGS1_k127_3844931_5	1009370.ALO_20117	1.707e-24	106.0	COG1003@1|root,COG1003@2|Bacteria,1TPK9@1239|Firmicutes,4H2E4@909932|Negativicutes	909932|Negativicutes	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
REGS1_k127_3844931_1	398767.Glov_2672	3.221e-206	649.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,42MQ1@68525|delta/epsilon subdivisions,2WJII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
REGS1_k127_3844931_4	269799.Gmet_3154	1.215e-49	181.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,43VCA@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
REGS1_k127_3844931_2	269799.Gmet_3155	4.297e-163	521.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,42QM6@68525|delta/epsilon subdivisions,2WJ8G@28221|Deltaproteobacteria,43TN6@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycine cleavage T protein (aminomethyl transferase)	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
REGS1_k127_3844931_0	269799.Gmet_0144	7.466e-254	793.0	COG0183@1|root,COG0183@2|Bacteria,1MU8C@1224|Proteobacteria,42N6X@68525|delta/epsilon subdivisions,2WJIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_3844931_3	156889.Mmc1_2003	3.948e-119	400.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
REGS1_k127_3849198_21	44251.PDUR_13340	8.906e-20	91.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1TPU5@1239|Firmicutes,4HCZG@91061|Bacilli,26VQ9@186822|Paenibacillaceae	91061|Bacilli	I	COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
REGS1_k127_3849198_11	794903.OPIT5_21325	1.451e-98	329.0	COG1116@1|root,COG1116@2|Bacteria,46ZAS@74201|Verrucomicrobia,3K8JW@414999|Opitutae	414999|Opitutae	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K15555	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.17.2	-	-	ABC_tran
REGS1_k127_3849198_17	448385.sce1323	5.515e-52	194.0	COG0600@1|root,COG0600@2|Bacteria,1R40J@1224|Proteobacteria	1224|Proteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K15554	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	BPD_transp_1
REGS1_k127_3849198_16	1120999.JONM01000009_gene438	1.574e-66	237.0	COG0600@1|root,COG0600@2|Bacteria,1MWS0@1224|Proteobacteria,2VKJC@28216|Betaproteobacteria,2KQTF@206351|Neisseriales	206351|Neisseriales	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
REGS1_k127_3849198_13	44251.PDUR_10230	2.471e-84	289.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	ko:K16129	ko01054,map01054	-	-	-	ko00000,ko00001,ko01008	-	-	-	Hydrolase_4,Methyltransf_11,Methyltransf_20,Methyltransf_25,Methyltransf_31,Ubie_methyltran
REGS1_k127_3849198_15	448385.sce1321	2.525e-71	254.0	COG0715@1|root,COG0715@2|Bacteria,1N2ZA@1224|Proteobacteria	1224|Proteobacteria	P	ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components	-	-	-	ko:K15553	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	NMT1
REGS1_k127_3849198_12	1254432.SCE1572_08970	2.663e-87	308.0	COG3746@1|root,COG3746@2|Bacteria,1R5WJ@1224|Proteobacteria	1224|Proteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3849198_14	720554.Clocl_2725	2.617e-84	284.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,3WIUE@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type metal ion transport system permease component	metP	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
REGS1_k127_3849198_7	720554.Clocl_2726	1.562e-129	421.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3WGFP@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
REGS1_k127_3849198_10	1123487.KB892842_gene4201	6.584e-100	335.0	COG1464@1|root,COG1464@2|Bacteria,1MUVY@1224|Proteobacteria,2VH5P@28216|Betaproteobacteria,2KYKQ@206389|Rhodocyclales	206389|Rhodocyclales	M	Belongs to the nlpA lipoprotein family	-	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
REGS1_k127_3849198_4	1125863.JAFN01000001_gene3062	7.619e-189	599.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,42MSQ@68525|delta/epsilon subdivisions,2WISJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	paaK-1	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
REGS1_k127_3849198_2	1449126.JQKL01000031_gene1133	1.671e-199	632.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,267KG@186813|unclassified Clostridiales	186801|Clostridia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	-	-	1.14.14.9	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	-	R02698,R03299	RC00046	ko00000,ko00001,ko01000	-	-	-	HpaB,HpaB_N
REGS1_k127_3849198_5	443143.GM18_2226	4.174e-180	567.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_3849198_18	243231.GSU1345	4.491e-47	173.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,43ABU@68525|delta/epsilon subdivisions,2WVAV@28221|Deltaproteobacteria,43UYX@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
REGS1_k127_3849198_0	316067.Geob_3821	1.105e-313	967.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,42MAA@68525|delta/epsilon subdivisions,2WJZC@28221|Deltaproteobacteria,43U9Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
REGS1_k127_3849198_20	1313421.JHBV01000039_gene2689	5.999e-32	141.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM,PMT_2
REGS1_k127_3849198_8	443143.GM18_0399	2.072e-121	399.0	COG2897@1|root,COG2897@2|Bacteria,1RKQN@1224|Proteobacteria,42SKC@68525|delta/epsilon subdivisions,2WPW7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,YceI
REGS1_k127_3849198_9	269799.Gmet_0120	1.19e-115	379.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria,43SDN@69541|Desulfuromonadales	28221|Deltaproteobacteria	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
REGS1_k127_3849198_19	269799.Gmet_3156	3.709e-34	134.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions,2WS29@28221|Deltaproteobacteria,43SQV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
REGS1_k127_3849198_3	316067.Geob_0534	2.563e-195	619.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKWB@28221|Deltaproteobacteria,43UDP@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_3849198_1	269799.Gmet_3158	4.771e-227	709.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U2Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_3849198_6	243231.GSU0368	4.043e-155	501.0	COG0729@1|root,COG0729@2|Bacteria,1QXN0@1224|Proteobacteria,43C43@68525|delta/epsilon subdivisions,2X7EI@28221|Deltaproteobacteria,43TF9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
REGS1_k127_385034_0	443144.GM21_3073	0.0	1068.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,43SXK@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN,TSCPD
REGS1_k127_385034_15	443144.GM21_3072	4.504e-138	447.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1R7FI@1224|Proteobacteria,4345X@68525|delta/epsilon subdivisions,2X5DX@28221|Deltaproteobacteria,43S5V@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
REGS1_k127_385034_21	443143.GM18_1056	1.476e-48	192.0	COG3170@1|root,COG3170@2|Bacteria,1Q4NY@1224|Proteobacteria,42ZIW@68525|delta/epsilon subdivisions,2WUTH@28221|Deltaproteobacteria,43UQ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
REGS1_k127_385034_12	243231.GSU1868	2.096e-146	472.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PYA@68525|delta/epsilon subdivisions,2WKM5@28221|Deltaproteobacteria,43SWI@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TIGRFAM cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
REGS1_k127_385034_23	269799.Gmet_1301	4.41e-16	82.0	COG4259@1|root,COG4259@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4810)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4810
REGS1_k127_385034_5	243231.GSU1866	2.492e-230	718.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,43UHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART Nucleotide binding protein, PINc	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
REGS1_k127_385034_14	443143.GM18_1940	3.12e-142	459.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,43UFF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_385034_16	269799.Gmet_1304	2.753e-96	323.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,43UBJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
REGS1_k127_385034_4	398767.Glov_1142	2.051e-233	729.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,43TK5@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
REGS1_k127_385034_8	443144.GM21_1937	7.137e-173	546.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42MI8@68525|delta/epsilon subdivisions,2WJDT@28221|Deltaproteobacteria,43SIZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM NAD-dependent epimerase dehydratase	uxs	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_385034_22	316067.Geob_2927	3.39e-29	119.0	COG2919@1|root,COG2919@2|Bacteria,1NM5U@1224|Proteobacteria,42X2K@68525|delta/epsilon subdivisions,2WSPM@28221|Deltaproteobacteria,43VHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
REGS1_k127_385034_3	243231.GSU1812	8.993e-265	826.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,43TTZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	arginyl-tRNA aminoacylation	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
REGS1_k127_385034_24	443143.GM18_1947	7.271e-09	63.0	COG3087@1|root,COG3087@2|Bacteria,1MYFG@1224|Proteobacteria,437BX@68525|delta/epsilon subdivisions,2X2HH@28221|Deltaproteobacteria,43VG4@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
REGS1_k127_385034_17	316067.Geob_3017	8.889e-86	289.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,42STM@68525|delta/epsilon subdivisions,2WPAD@28221|Deltaproteobacteria,43SZ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
REGS1_k127_385034_10	269799.Gmet_1960	7.849e-168	531.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,42MCV@68525|delta/epsilon subdivisions,2WJI2@28221|Deltaproteobacteria,43T75@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM aminoacyl-tRNA synthetase class Ib	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
REGS1_k127_385034_18	269799.Gmet_1959	1.711e-84	287.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,43SVJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
REGS1_k127_385034_19	316067.Geob_3014	7.431e-70	241.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,43US2@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
REGS1_k127_385034_1	316067.Geob_3012	3.225e-319	1000.0	COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,1MU2X@1224|Proteobacteria,42MJJ@68525|delta/epsilon subdivisions,2WJBN@28221|Deltaproteobacteria,43U0J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	CBS domain containing protein	ccaA	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd
REGS1_k127_385034_20	243231.GSU3447	1.14e-63	222.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,42RHG@68525|delta/epsilon subdivisions,2WQ59@28221|Deltaproteobacteria,43URV@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Redoxin	prx-4	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_385034_6	316067.Geob_3466	2.291e-227	740.0	COG1305@1|root,COG1305@2|Bacteria,1PEH8@1224|Proteobacteria	1224|Proteobacteria	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
REGS1_k127_385034_25	694431.DESACE_06870	2.403e-08	68.0	COG0791@1|root,COG1388@1|root,COG0791@2|Bacteria,COG1388@2|Bacteria,1N0EE@1224|Proteobacteria,42SGG@68525|delta/epsilon subdivisions,2WPF3@28221|Deltaproteobacteria,2M7Q6@213113|Desulfurellales	28221|Deltaproteobacteria	M	NlpC/P60 family	-	-	-	ko:K19223	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	CBM50	-	LysM,NLPC_P60
REGS1_k127_385034_13	316067.Geob_3465	2.219e-142	486.0	COG2373@1|root,COG2931@1|root,COG4257@1|root,COG5029@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,COG4257@2|Bacteria,COG5029@2|Bacteria	2|Bacteria	O	Prenyltransferase	-	-	-	ko:K13277	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03110	-	-	-	A2M,An_peroxidase,CHRD,CarboxypepD_reg,Prenyltrans
REGS1_k127_385034_2	316067.Geob_3308	1.384e-275	899.0	COG2373@1|root,COG3291@1|root,COG5276@1|root,COG2373@2|Bacteria,COG3291@2|Bacteria,COG5276@2|Bacteria,1R7A1@1224|Proteobacteria,42Y4U@68525|delta/epsilon subdivisions,2WU72@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_1,IgGFc_binding
REGS1_k127_385034_26	404380.Gbem_1922	1.09e-07	66.0	COG1361@1|root,COG3055@1|root,COG3420@1|root,COG5184@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,COG3420@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
REGS1_k127_385034_7	269799.Gmet_0883	1.814e-199	623.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,42QC6@68525|delta/epsilon subdivisions,2WIRV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	arnA	-	1.1.1.305,2.1.2.13	ko:K10011,ko:K12449	ko00520,ko01100,ko01503,map00520,map01100,map01503	M00721,M00761	R01384,R01386,R07658,R07660	RC00026,RC00508,RC01575,RC01811,RC01812	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase,Formyl_trans_C,Formyl_trans_N
REGS1_k127_385034_11	316067.Geob_1550	1.019e-150	481.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,42QSB@68525|delta/epsilon subdivisions,2WMWD@28221|Deltaproteobacteria,43V50@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Formyl transferase, C-terminal domain	arnG	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
REGS1_k127_385034_9	404380.Gbem_2981	3.365e-169	535.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,42NYX@68525|delta/epsilon subdivisions,2WJV8@28221|Deltaproteobacteria,43THT@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	arnC	-	2.4.2.53	ko:K10012,ko:K20534	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8,4.D.2.1.9	GT2	-	Glycos_transf_2
REGS1_k127_3865900_14	443143.GM18_4011	3.515e-25	106.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria,43T72@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	ATP-binding region, ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_3865900_2	1120999.JONM01000009_gene418	1.326e-132	444.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2W3SC@28216|Betaproteobacteria,2KTW2@206351|Neisseriales	1224|Proteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	mcp40H-21	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,CHASE3,HAMP,MCPsignal
REGS1_k127_3865900_4	443143.GM18_0072	7.916e-109	360.0	COG2204@1|root,COG2204@2|Bacteria,1QWDW@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_3865900_12	1247963.JPHU01000007_gene1628	1.872e-45	182.0	COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
REGS1_k127_3865900_15	1111479.AXAR01000020_gene1212	1.05e-06	51.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HDZ4@91061|Bacilli	91061|Bacilli	T	Histidine kinase	-	-	2.7.13.3	ko:K07642	ko02020,map02020	M00450,M00645,M00646,M00648	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
REGS1_k127_3865900_0	404380.Gbem_1227	1.51e-231	744.0	COG0642@1|root,COG2770@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_1
REGS1_k127_3865900_6	443143.GM18_0068	1.053e-90	324.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42P9E@68525|delta/epsilon subdivisions,2WMH3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HAMP,HATPase_c,HisKA
REGS1_k127_3865900_13	1283284.AZUK01000001_gene1841	6.519e-38	163.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9,Reg_prop
REGS1_k127_3865900_7	443143.GM18_2642	2.006e-82	295.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_3865900_9	443143.GM18_2642	1.809e-69	256.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_3865900_8	927677.ALVU02000001_gene3916	1.678e-76	265.0	COG0226@1|root,COG0226@2|Bacteria,1G817@1117|Cyanobacteria	1117|Cyanobacteria	P	Phosphate ABC transporter substrate-binding protein, PhoT family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_3865900_10	443143.GM18_4013	1.507e-67	235.0	COG0835@1|root,COG0835@2|Bacteria,1RJKY@1224|Proteobacteria,42SN3@68525|delta/epsilon subdivisions,2WPCG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_3865900_1	443143.GM18_4014	7.349e-162	526.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,42NZW@68525|delta/epsilon subdivisions,2WMDS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM MCP methyltransferase, CheR-type	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,TPR_16,TPR_8
REGS1_k127_3865900_11	443143.GM18_4015	4.578e-47	174.0	COG0835@1|root,COG0835@2|Bacteria,1ND5U@1224|Proteobacteria,42VHE@68525|delta/epsilon subdivisions,2WR9A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_3865900_5	269799.Gmet_2403	8.65e-97	326.0	COG0457@1|root,COG0457@2|Bacteria,1RGQZ@1224|Proteobacteria,42RWT@68525|delta/epsilon subdivisions,2WNFK@28221|Deltaproteobacteria,43SIH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_2,TPR_8
REGS1_k127_3865900_3	1259795.ARJK01000003_gene1118	8.255e-115	395.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,42FHW@68295|Thermoanaerobacterales	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
REGS1_k127_3867970_7	443144.GM21_1254	9.042e-115	376.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2WKY2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_int_SAM_3,Phage_integrase
REGS1_k127_3867970_10	316067.Geob_2775	1.58e-34	138.0	COG0457@1|root,COG0457@2|Bacteria	316067.Geob_2775|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3867970_5	243231.GSU2044	2.206e-135	445.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
REGS1_k127_3867970_2	1121918.ARWE01000001_gene2479	5.495e-192	625.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,Response_reg
REGS1_k127_3867970_3	338966.Ppro_3139	6.299e-173	566.0	COG1639@1|root,COG3852@1|root,COG1639@2|Bacteria,COG3852@2|Bacteria,1R444@1224|Proteobacteria,42MX7@68525|delta/epsilon subdivisions,2WJHH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HDOD domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HDOD,HisKA
REGS1_k127_3867970_0	243231.GSU1561	1.191e-289	902.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria,43BJ8@68525|delta/epsilon subdivisions,2WUGK@28221|Deltaproteobacteria,43U2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K21464	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_1671	Transgly,Transpeptidase
REGS1_k127_3867970_1	443143.GM18_3857	9.696e-197	623.0	COG0366@1|root,COG0366@2|Bacteria,1MVQA@1224|Proteobacteria,42QH9@68525|delta/epsilon subdivisions,2WKM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM alpha amylase, catalytic region	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_20
REGS1_k127_3867970_11	316067.Geob_0435	1.77e-27	121.0	COG0745@1|root,COG0745@2|Bacteria	316067.Geob_0435|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3867970_8	269799.Gmet_2158	1.787e-76	262.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,43UZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_3867970_6	269799.Gmet_2186	2.247e-121	400.0	COG4251@1|root,COG4753@1|root,COG4251@2|Bacteria,COG4753@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
REGS1_k127_3867970_4	338966.Ppro_1396	8.284e-157	531.0	COG2203@1|root,COG4191@1|root,COG4936@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42NFR@68525|delta/epsilon subdivisions,2WPBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,NMT1,PAS_4,PAS_9,PocR,SBP_bac_3,dCache_1
REGS1_k127_3867970_9	877455.Metbo_1775	4.693e-53	214.0	arCOG03567@1|root,arCOG07605@1|root,arCOG03567@2157|Archaea,arCOG07605@2157|Archaea	2157|Archaea	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,MEDS,PAS,PAS_3,PAS_4,PAS_9
REGS1_k127_3867970_13	386456.JQKN01000007_gene3171	9.229e-06	49.0	arCOG02342@1|root,arCOG04001@1|root,arCOG02342@2157|Archaea,arCOG04001@2157|Archaea	2157|Archaea	T	tigrfam pas	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	BAT,Cache_3-Cache_2,GAF_2,HAMP,HATPase_c,HTH_10,HisKA,HisKA_2,MCPsignal,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1,sCache_3_3
REGS1_k127_3870777_4	443143.GM18_3108	1.027e-155	493.0	COG5557@1|root,COG5557@2|Bacteria,1MWYI@1224|Proteobacteria,42PH3@68525|delta/epsilon subdivisions,2WJZH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
REGS1_k127_3870777_3	443144.GM21_1124	4.718e-166	527.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42S59@68525|delta/epsilon subdivisions,2WNGW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	hybA	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4,TAT_signal
REGS1_k127_3870777_1	443143.GM18_3110	2.102e-214	668.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	hybS	-	1.12.2.1,1.12.99.6	ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
REGS1_k127_3870777_5	243231.GSU0139	3.875e-40	158.0	COG1981@1|root,COG1981@2|Bacteria,1NM81@1224|Proteobacteria,42Y3M@68525|delta/epsilon subdivisions,2WSK7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3870777_0	316067.Geob_1632	3.162e-245	774.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MRH@68525|delta/epsilon subdivisions,2WM8D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase HAMP	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,sCache_3_3
REGS1_k127_3870777_2	243231.GSU0776	5.674e-188	597.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P5K@68525|delta/epsilon subdivisions,2WIKI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_4051569_9	1463895.JODA01000041_gene2952	2.621e-44	164.0	COG0346@1|root,COG0346@2|Bacteria,2IHCN@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase,Glyoxalase_4
REGS1_k127_4051569_1	1454004.AW11_00467	2.621e-314	970.0	COG2942@1|root,COG2942@2|Bacteria,1R8S3@1224|Proteobacteria	1224|Proteobacteria	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
REGS1_k127_4051569_13	118173.KB235914_gene3289	1.893e-26	111.0	COG1366@1|root,COG1366@2|Bacteria,1G7WI@1117|Cyanobacteria,1HC83@1150|Oscillatoriales	1117|Cyanobacteria	T	transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
REGS1_k127_4051569_0	1173028.ANKO01000017_gene198	0.0	1155.0	COG1523@1|root,COG1523@2|Bacteria,1G0PW@1117|Cyanobacteria,1H8QW@1150|Oscillatoriales	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
REGS1_k127_4051569_11	1122951.ATUE01000006_gene851	1.052e-35	141.0	2DVNB@1|root,32UZS@2|Bacteria,1N65J@1224|Proteobacteria,1SF9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4051569_12	82654.Pse7367_3453	2.704e-32	128.0	COG1366@1|root,COG1366@2|Bacteria,1G8B3@1117|Cyanobacteria,1HCRD@1150|Oscillatoriales	1117|Cyanobacteria	T	transporter antisigma-factor antagonist STAS	-	-	-	-	-	-	-	-	-	-	-	-	STAS
REGS1_k127_4051569_10	1121382.JQKG01000002_gene4447	5.715e-42	162.0	COG2172@1|root,COG2172@2|Bacteria	2|Bacteria	T	sigma factor antagonist activity	btrW	-	2.7.11.1,3.1.3.3	ko:K04757,ko:K07315	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2,SpoIIE
REGS1_k127_4051569_7	573370.DMR_35230	3.549e-52	190.0	COG0778@1|root,COG0778@2|Bacteria,1PDTZ@1224|Proteobacteria,42SQ3@68525|delta/epsilon subdivisions,2WPC5@28221|Deltaproteobacteria,2MB1K@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_4051569_2	398767.Glov_0709	9.946e-240	760.0	COG2208@1|root,COG3850@1|root,COG2208@2|Bacteria,COG3850@2|Bacteria,1MXJQ@1224|Proteobacteria,42U7B@68525|delta/epsilon subdivisions,2WQA7@28221|Deltaproteobacteria,43VZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE
REGS1_k127_4051569_5	338966.Ppro_1527	3e-113	386.0	COG2208@1|root,COG2972@1|root,COG2208@2|Bacteria,COG2972@2|Bacteria,1MXJQ@1224|Proteobacteria,42MFQ@68525|delta/epsilon subdivisions,2WIJ4@28221|Deltaproteobacteria,43VZ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sigma factor PP2C-like phosphatases	-	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	HAMP,SpoIIE,dCache_1
REGS1_k127_4051569_4	398767.Glov_0708	1.287e-113	377.0	COG2984@1|root,COG2984@2|Bacteria,1PW8R@1224|Proteobacteria,4379S@68525|delta/epsilon subdivisions,2WNU3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
REGS1_k127_4051569_8	398767.Glov_0706	6.537e-52	196.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,42WGW@68525|delta/epsilon subdivisions,2WRWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
REGS1_k127_4051569_3	398767.Glov_0706	1.168e-123	405.0	COG0679@1|root,COG0679@2|Bacteria,1P2SH@1224|Proteobacteria,42WGW@68525|delta/epsilon subdivisions,2WRWV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
REGS1_k127_4051569_14	323259.Mhun_0062	1.456e-13	75.0	COG1366@1|root,arCOG06891@2157|Archaea	2157|Archaea	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
REGS1_k127_4051569_6	690850.Desaf_0594	9.59e-80	281.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2M9S8@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the LDH MDH superfamily. LDH family	ldh	-	1.1.1.27,1.1.1.37	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R00703,R01000,R03104,R07136	RC00031,RC00044	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
REGS1_k127_4051569_15	593117.TGAM_1314	1.068e-09	70.0	COG1226@1|root,arCOG03127@2157|Archaea,2XZ28@28890|Euryarchaeota,243AD@183968|Thermococci	183968|Thermococci	P	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
REGS1_k127_4106353_4	316067.Geob_0822	2.627e-48	181.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42PVD@68525|delta/epsilon subdivisions,2WM2C@28221|Deltaproteobacteria,43SUX@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
REGS1_k127_4106353_3	316067.Geob_0823	5.504e-52	188.0	COG1708@1|root,COG1708@2|Bacteria,1NKZT@1224|Proteobacteria,430VC@68525|delta/epsilon subdivisions,2WVUS@28221|Deltaproteobacteria,43VAP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
REGS1_k127_4106353_2	269799.Gmet_2776	1.636e-71	249.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,42WA3@68525|delta/epsilon subdivisions,2WSEN@28221|Deltaproteobacteria,43UNM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
REGS1_k127_4106353_0	316067.Geob_0826	2.498e-155	502.0	COG0768@1|root,COG0768@2|Bacteria,1R7A0@1224|Proteobacteria,42MJC@68525|delta/epsilon subdivisions,2WJZ2@28221|Deltaproteobacteria,43T9I@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM penicillin-binding protein transpeptidase	pbp4	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
REGS1_k127_4106353_1	316067.Geob_0827	1.06e-140	459.0	COG1295@1|root,COG1959@1|root,COG1295@2|Bacteria,COG1959@2|Bacteria,1QICW@1224|Proteobacteria,42MBW@68525|delta/epsilon subdivisions,2WK2Z@28221|Deltaproteobacteria,43SWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Rrf2,Virul_fac_BrkB
REGS1_k127_4106353_5	316067.Geob_0828	5.248e-35	136.0	COG4980@1|root,COG4980@2|Bacteria,1NB49@1224|Proteobacteria,42W0M@68525|delta/epsilon subdivisions,2WRVH@28221|Deltaproteobacteria,43SQE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
REGS1_k127_4106353_6	243231.GSU3583	9.045e-24	106.0	COG4768@1|root,COG4768@2|Bacteria,1P1C4@1224|Proteobacteria,431JC@68525|delta/epsilon subdivisions,2WWRI@28221|Deltaproteobacteria,43VMG@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
REGS1_k127_415681_3	338966.Ppro_3649	4.685e-127	411.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,43SU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
REGS1_k127_415681_2	316067.Geob_2562	2.586e-191	604.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,42PU9@68525|delta/epsilon subdivisions,2WNCM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_415681_0	338966.Ppro_3639	0.0	1208.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
REGS1_k127_415681_4	338966.Ppro_3638	3.176e-42	156.0	COG1937@1|root,COG1937@2|Bacteria,1Q5WJ@1224|Proteobacteria,43A8W@68525|delta/epsilon subdivisions,2WSSR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
REGS1_k127_415681_1	243231.GSU1198	3.69e-243	756.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,43U5C@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
REGS1_k127_4252419_16	316067.Geob_0053	5.035e-09	63.0	COG0484@1|root,COG3880@1|root,COG0484@2|Bacteria,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_4252419_12	289376.THEYE_A1167	9.378e-28	127.0	COG0607@1|root,COG2897@1|root,COG0607@2|Bacteria,COG2897@2|Bacteria	2|Bacteria	P	thiosulfate sulfurtransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_4252419_6	443144.GM21_3558	1.875e-96	323.0	COG0755@1|root,COG0755@2|Bacteria,1RCCI@1224|Proteobacteria,42PVM@68525|delta/epsilon subdivisions,2WJ7I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Cytochrome c assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_4252419_7	443144.GM21_3557	3.865e-95	328.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
REGS1_k127_4252419_11	443143.GM18_0616	1.558e-34	147.0	COG4346@1|root,COG4346@2|Bacteria	2|Bacteria	O	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	GT87,PMT,PMT_2,PMT_4TMC
REGS1_k127_4252419_9	861299.J421_0879	2.626e-56	214.0	COG1232@1|root,COG1232@2|Bacteria,1ZUPK@142182|Gemmatimonadetes	142182|Gemmatimonadetes	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
REGS1_k127_4252419_0	316067.Geob_0059	2.687e-272	849.0	COG4262@1|root,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synth
REGS1_k127_4252419_4	269799.Gmet_0588	2.142e-106	367.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
REGS1_k127_4252419_3	269799.Gmet_0568	1.515e-138	446.0	COG3221@1|root,COG3221@2|Bacteria,1NPBT@1224|Proteobacteria,42NX8@68525|delta/epsilon subdivisions,2X5DW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
REGS1_k127_4252419_10	316067.Geob_3349	8.316e-39	151.0	COG0457@1|root,COG0457@2|Bacteria	316067.Geob_3349|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4252419_2	269799.Gmet_0570	7.437e-152	486.0	COG2391@1|root,COG2391@2|Bacteria,1NCH7@1224|Proteobacteria,42NKG@68525|delta/epsilon subdivisions,2WJFC@28221|Deltaproteobacteria,43TGF@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
REGS1_k127_4252419_5	398767.Glov_1301	1.223e-98	332.0	COG2067@1|root,COG2067@2|Bacteria,1RFDS@1224|Proteobacteria,42UMQ@68525|delta/epsilon subdivisions,2WQY1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Protein of unknown function (DUF3187)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3187
REGS1_k127_4252419_1	269799.Gmet_0609	3.372e-272	849.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,43UHX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
REGS1_k127_4252419_8	269799.Gmet_2814	7.538e-62	221.0	COG0546@1|root,COG0546@2|Bacteria,1RHAA@1224|Proteobacteria,43EWP@68525|delta/epsilon subdivisions,2X9XQ@28221|Deltaproteobacteria,43URI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
REGS1_k127_4252419_13	443144.GM21_3343	3.649e-18	84.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
REGS1_k127_4255867_17	443143.GM18_1914	7.941e-35	139.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,43UTI@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4255867_18	443143.GM18_1913	3.843e-32	138.0	COG3170@1|root,COG3170@2|Bacteria,1NIKF@1224|Proteobacteria,42XZ9@68525|delta/epsilon subdivisions,2WTH6@28221|Deltaproteobacteria,43STG@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
REGS1_k127_4255867_0	443144.GM21_1905	0.0	1206.0	COG0480@1|root,COG0480@2|Bacteria,1R0V4@1224|Proteobacteria,42M1F@68525|delta/epsilon subdivisions,2WIYM@28221|Deltaproteobacteria,43RZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	elongation factor Tu domain 2 protein	fusA-1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_4255867_3	316067.Geob_2385	1.119e-134	433.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,43S2T@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
REGS1_k127_4255867_8	316067.Geob_2384	2.04e-113	374.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,43T0U@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
REGS1_k127_4255867_7	316067.Geob_2383	5.114e-117	383.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,43T21@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
REGS1_k127_4255867_2	316067.Geob_2379	3.105e-165	526.0	COG3005@1|root,COG3005@2|Bacteria,1NJY9@1224|Proteobacteria,42XJ4@68525|delta/epsilon subdivisions,2WSQ4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	12 heme-binding sites	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_4255867_12	316067.Geob_0049	6.278e-70	246.0	COG0226@1|root,COG0226@2|Bacteria,1MW2Z@1224|Proteobacteria,42SWB@68525|delta/epsilon subdivisions,2WPMC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_4255867_11	1121918.ARWE01000001_gene3198	4.309e-78	276.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43DFM@68525|delta/epsilon subdivisions,2X8MI@28221|Deltaproteobacteria,43UST@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_4255867_10	443143.GM18_0072	8.311e-103	340.0	COG2204@1|root,COG2204@2|Bacteria,1QWDW@1224|Proteobacteria	1224|Proteobacteria	T	Pfam Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_4255867_15	1121918.ARWE01000001_gene3195	1.908e-60	221.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	ko:K02660,ko:K11525	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,EAL,GAF,GGDEF,HAMP,MCPsignal,PAS_3,PAS_4,PAS_7,dCache_1
REGS1_k127_4255867_5	269799.Gmet_2439	3.142e-122	396.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,42T7Z@68525|delta/epsilon subdivisions,2X7MA@28221|Deltaproteobacteria,43W2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	nikO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
REGS1_k127_4255867_9	316067.Geob_3338	2.93e-105	348.0	COG0619@1|root,COG0619@2|Bacteria,1R2DN@1224|Proteobacteria,43B6A@68525|delta/epsilon subdivisions,2X6JT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	nikQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
REGS1_k127_4255867_4	522306.CAP2UW1_3076	1.114e-123	409.0	COG0310@1|root,COG0310@2|Bacteria,1R70A@1224|Proteobacteria,2VS85@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Cobalamin (Vitamin B12) biosynthesis CbiM protein	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
REGS1_k127_4255867_16	338966.Ppro_1242	2.322e-58	213.0	COG1452@1|root,COG1452@2|Bacteria,1QX10@1224|Proteobacteria,43CGX@68525|delta/epsilon subdivisions,2X7S3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
REGS1_k127_4255867_19	1382359.JIAL01000001_gene1687	2.504e-23	104.0	COG0745@1|root,COG0745@2|Bacteria,3Y4C2@57723|Acidobacteria,2JJ42@204432|Acidobacteriia	204432|Acidobacteriia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_4255867_13	1123368.AUIS01000020_gene1076	5.9e-68	252.0	COG2203@1|root,COG4251@1|root,COG2203@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,1T5R6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4
REGS1_k127_4255867_21	298386.PBPRB1928	5.013e-21	108.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	algC	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	GAF,GGDEF,HATPase_c,HisKA,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_4255867_14	243231.GSU0203	1.589e-62	222.0	COG2068@1|root,COG2068@2|Bacteria,1RAAE@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Metal-dependent phosphohydrolase, HD	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	HD,NTP_transf_3
REGS1_k127_4255867_6	243231.GSU0202	3.515e-119	387.0	COG1975@1|root,COG1975@2|Bacteria,1MXKU@1224|Proteobacteria,42QUY@68525|delta/epsilon subdivisions,2WMVP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3,XdhC_C,XdhC_CoxI
REGS1_k127_4255867_1	243231.GSU0201	0.0	1139.0	COG1529@1|root,COG1529@2|Bacteria,1QTTJ@1224|Proteobacteria,42NU9@68525|delta/epsilon subdivisions,2WKXG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding	-	-	1.3.99.16	ko:K07303	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C2,Fer2,Fer2_2
REGS1_k127_4255867_20	243231.GSU0200	6.681e-23	98.0	COG2080@1|root,COG2080@2|Bacteria,1RD8C@1224|Proteobacteria,42SQU@68525|delta/epsilon subdivisions,2WPRP@28221|Deltaproteobacteria,43W1M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	[2Fe-2S] binding domain	-	-	1.3.99.16	ko:K07302	-	-	-	-	ko00000,ko01000	-	-	-	Fer2,Fer2_2
REGS1_k127_4351198_9	316067.Geob_3332	5.374e-90	300.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,43TAP@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
REGS1_k127_4351198_4	316067.Geob_3333	5.353e-139	448.0	COG0568@1|root,COG0568@2|Bacteria,1MUDI@1224|Proteobacteria,42P4U@68525|delta/epsilon subdivisions,2WKXR@28221|Deltaproteobacteria,43TMK@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoS	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_4351198_8	269799.Gmet_1420	6.907e-94	312.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QSI@68525|delta/epsilon subdivisions,2WMNJ@28221|Deltaproteobacteria,43TVI@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_4351198_7	316067.Geob_3335	3.161e-103	344.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,42N0I@68525|delta/epsilon subdivisions,2WMUX@28221|Deltaproteobacteria,43T33@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
REGS1_k127_4351198_5	316067.Geob_2991	3.485e-117	385.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42NZP@68525|delta/epsilon subdivisions,2WKZA@28221|Deltaproteobacteria,43S59@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_4351198_11	398767.Glov_1951	4.214e-45	165.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,42TQH@68525|delta/epsilon subdivisions,2WQ2M@28221|Deltaproteobacteria,43V3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
REGS1_k127_4351198_10	269799.Gmet_1937	3.028e-84	289.0	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,43UMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
REGS1_k127_4351198_6	398767.Glov_2703	1.21e-107	349.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WPAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
REGS1_k127_4351198_2	316067.Geob_2890	3.839e-267	826.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
REGS1_k127_4351198_3	398767.Glov_2701	1.841e-155	492.0	COG0047@1|root,COG0047@2|Bacteria,1MU4Y@1224|Proteobacteria,42MNY@68525|delta/epsilon subdivisions,2WJ6C@28221|Deltaproteobacteria,43TFB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	CobB/CobQ-like glutamine amidotransferase domain	purQ	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
REGS1_k127_4351198_1	338966.Ppro_1151	1.958e-282	878.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,42MV3@68525|delta/epsilon subdivisions,2WJZB@28221|Deltaproteobacteria,43SX6@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
REGS1_k127_4351198_0	338966.Ppro_1147	2.742e-305	942.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,43TKA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
REGS1_k127_4393636_13	316067.Geob_1283	1.141e-49	194.0	COG1361@1|root,COG1404@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin_3,DUF11,DUF4347,He_PIG,PATR
REGS1_k127_4393636_5	1304885.AUEY01000104_gene2548	6.656e-109	362.0	COG0702@1|root,COG0702@2|Bacteria,1Q438@1224|Proteobacteria,439WM@68525|delta/epsilon subdivisions,2X29K@28221|Deltaproteobacteria,2MPBK@213118|Desulfobacterales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
REGS1_k127_4393636_14	404589.Anae109_0589	9.127e-36	142.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria	1224|Proteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
REGS1_k127_4393636_11	316067.Geob_2739	1.747e-52	192.0	29IJ4@1|root,313M6@2|Bacteria,1R385@1224|Proteobacteria,43DJI@68525|delta/epsilon subdivisions,2X8QT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
REGS1_k127_4393636_0	243231.GSU3395	0.0	1319.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1MV93@1224|Proteobacteria,42MQH@68525|delta/epsilon subdivisions,2WJPV@28221|Deltaproteobacteria,43U56@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Oxidizes proline to glutamate for use as a carbon and nitrogen source	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	iAF987.Gmet_3512	Aldedh,Pro_dh
REGS1_k127_4393636_4	404380.Gbem_1886	6.628e-116	379.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,42MXZ@68525|delta/epsilon subdivisions,2WJWG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
REGS1_k127_4393636_2	443143.GM18_1704	2.67e-173	549.0	COG1915@1|root,COG1915@2|Bacteria,1PZ72@1224|Proteobacteria,42MME@68525|delta/epsilon subdivisions,2WJSV@28221|Deltaproteobacteria,43SKS@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM LOR SDH bifunctional enzyme conserved region	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
REGS1_k127_4393636_7	443144.GM21_2148	6.633e-70	245.0	COG4446@1|root,COG4446@2|Bacteria,1N31A@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	MA20_07395	-	-	-	-	-	-	-	-	-	-	-	DUF1499
REGS1_k127_4393636_9	404380.Gbem_1216	3.255e-65	229.0	COG2340@1|root,COG2340@2|Bacteria,1N566@1224|Proteobacteria,42UZI@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
REGS1_k127_4393636_10	243231.GSU1664	4.231e-55	196.0	COG1547@1|root,COG1547@2|Bacteria,1NPV3@1224|Proteobacteria,42XAN@68525|delta/epsilon subdivisions,2WSKH@28221|Deltaproteobacteria,43VMV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF309)	-	-	-	ko:K09763	-	-	-	-	ko00000	-	-	-	DUF309
REGS1_k127_4393636_12	338966.Ppro_1790	1.534e-50	182.0	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,42VMT@68525|delta/epsilon subdivisions,2WPFB@28221|Deltaproteobacteria,43V6U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	FxsA cytoplasmic membrane protein	fsxA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
REGS1_k127_4393636_6	443143.GM18_1260	1.053e-82	302.0	COG4251@1|root,COG4936@1|root,COG5000@1|root,COG4251@2|Bacteria,COG4936@2|Bacteria,COG5000@2|Bacteria,1NSQ1@1224|Proteobacteria,42QPS@68525|delta/epsilon subdivisions,2WMWT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,dCache_1
REGS1_k127_4393636_15	865861.AZSU01000008_gene677	1.278e-23	117.0	COG4585@1|root,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,36FHU@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	degS	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DegS,HATPase_c,HisKA_3
REGS1_k127_4393636_8	56780.SYN_01953	4.71e-67	234.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42R03@68525|delta/epsilon subdivisions,2WMTZ@28221|Deltaproteobacteria,2MRIP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_4393636_3	316067.Geob_0557	9.626e-153	503.0	COG1352@1|root,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,42T12@68525|delta/epsilon subdivisions,2WPTY@28221|Deltaproteobacteria,43TRF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg,TPR_16
REGS1_k127_4393636_1	1121918.ARWE01000001_gene546	1.645e-192	622.0	COG0834@1|root,COG2202@1|root,COG2204@1|root,COG3852@1|root,COG4191@1|root,COG0834@2|Bacteria,COG2202@2|Bacteria,COG2204@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_4672346_3	316067.Geob_0770	2.744e-38	150.0	2E47B@1|root,32Z37@2|Bacteria,1NC7T@1224|Proteobacteria,42VYF@68525|delta/epsilon subdivisions,2WRN2@28221|Deltaproteobacteria,43VKY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4672346_4	243231.GSU3080	7.312e-34	138.0	2DYRB@1|root,34AST@2|Bacteria,1P1IT@1224|Proteobacteria,431T7@68525|delta/epsilon subdivisions,2WX11@28221|Deltaproteobacteria,43VFP@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4672346_1	935840.JAEQ01000001_gene2780	2.394e-99	330.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,2TS16@28211|Alphaproteobacteria,43IV6@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	L	IstB-like ATP binding protein	MA20_10895	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
REGS1_k127_4672346_0	398767.Glov_0886	2.002e-282	874.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42SM4@68525|delta/epsilon subdivisions,2WPVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
REGS1_k127_4672346_2	243231.GSU1657	3.036e-46	173.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,43TMI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
REGS1_k127_4741386_24	404380.Gbem_1771	2.999e-92	310.0	COG0489@1|root,COG0489@2|Bacteria,1MVI9@1224|Proteobacteria,42QS3@68525|delta/epsilon subdivisions,2WMX0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Capsular exopolysaccharide family	-	-	2.7.10.1	ko:K08252	-	-	-	-	ko00000,ko01000	-	-	-	AAA_31,CbiA,ParA
REGS1_k127_4741386_17	316067.Geob_2980	1.375e-136	449.0	COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,42PYQ@68525|delta/epsilon subdivisions,2WKRC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
REGS1_k127_4741386_19	404380.Gbem_1769	1.671e-112	369.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,43T8T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis/export protein	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
REGS1_k127_4741386_13	338966.Ppro_2476	2.889e-155	502.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria,43S24@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
REGS1_k127_4741386_0	338966.Ppro_2478	0.0	1166.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42P80@68525|delta/epsilon subdivisions,2WMCB@28221|Deltaproteobacteria,43TGI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
REGS1_k127_4741386_42	935836.JAEL01000201_gene4586	1.79e-05	51.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4741386_5	243231.GSU1219	4.667e-239	745.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,43T78@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_4741386_38	1232410.KI421413_gene579	4.784e-16	82.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,42XRW@68525|delta/epsilon subdivisions,2WT0E@28221|Deltaproteobacteria,43VPM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
REGS1_k127_4741386_26	316067.Geob_3154	5.193e-83	297.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,SLH
REGS1_k127_4741386_20	269799.Gmet_1595	1.946e-102	336.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,43U3H@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	yrdC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
REGS1_k127_4741386_9	269799.Gmet_1594	5.876e-197	617.0	COG2309@1|root,COG2309@2|Bacteria,1MW2Y@1224|Proteobacteria,42P6P@68525|delta/epsilon subdivisions,2WJF8@28221|Deltaproteobacteria,43U0T@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM peptidase M29, aminopeptidase II	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
REGS1_k127_4741386_28	316067.Geob_2699	1.168e-59	209.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria,43SJ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
REGS1_k127_4741386_14	269799.Gmet_1592	1.899e-148	480.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42P7N@68525|delta/epsilon subdivisions,2WJKE@28221|Deltaproteobacteria,43TZJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_4741386_1	269799.Gmet_1591	0.0	1125.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,43TFC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
REGS1_k127_4741386_33	316067.Geob_2696	2.207e-43	159.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,43V8I@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
REGS1_k127_4741386_22	269799.Gmet_1589	4.002e-98	330.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,43UI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
REGS1_k127_4741386_16	243231.GSU1590	3.287e-142	458.0	COG0618@1|root,COG0618@2|Bacteria,1RAUQ@1224|Proteobacteria,42RKG@68525|delta/epsilon subdivisions,2WN0X@28221|Deltaproteobacteria,43TAU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM phosphoesterase, RecJ domain protein	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
REGS1_k127_4741386_34	269799.Gmet_1587	1.81e-41	155.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,42U0Y@68525|delta/epsilon subdivisions,2WR00@28221|Deltaproteobacteria,43V4Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
REGS1_k127_4741386_2	316067.Geob_2692	0.0	1125.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,42M5Q@68525|delta/epsilon subdivisions,2WIIX@28221|Deltaproteobacteria,43UH5@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
REGS1_k127_4741386_30	243231.GSU1587	9.413e-54	195.0	COG1358@1|root,COG2740@1|root,COG1358@2|Bacteria,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,42XP3@68525|delta/epsilon subdivisions,2WT0X@28221|Deltaproteobacteria,43UWT@69541|Desulfuromonadales	28221|Deltaproteobacteria	JK	ribosomal protein L7Ae L30e S12e Gadd45	ylxRQ	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448,Ribosomal_L7Ae
REGS1_k127_4741386_10	269799.Gmet_1584	1.893e-185	586.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,43U8I@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
REGS1_k127_4741386_27	243231.GSU1585	1.098e-66	230.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQYV@28221|Deltaproteobacteria,43V1S@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
REGS1_k127_4741386_6	443144.GM21_1625	3.703e-229	732.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NGS@68525|delta/epsilon subdivisions,2WIWF@28221|Deltaproteobacteria,43TQ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
REGS1_k127_4741386_12	316067.Geob_3392	1.472e-155	517.0	COG0457@1|root,COG0741@1|root,COG1729@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,COG1729@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WPM9@28221|Deltaproteobacteria,43U8J@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM Lytic transglycosylase catalytic	mltE	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,TPR_16,TPR_6,TPR_8
REGS1_k127_4741386_32	316067.Geob_3394	2.911e-51	186.0	COG1846@1|root,COG1846@2|Bacteria,1RH1F@1224|Proteobacteria,42VBV@68525|delta/epsilon subdivisions,2WRQ4@28221|Deltaproteobacteria,43V73@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR
REGS1_k127_4741386_18	316067.Geob_3395	1.088e-119	399.0	COG1538@1|root,COG1538@2|Bacteria,1Q1F4@1224|Proteobacteria,42NUU@68525|delta/epsilon subdivisions,2WK3P@28221|Deltaproteobacteria,43TTM@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_4741386_21	398767.Glov_0105	1.434e-101	335.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,42QUZ@68525|delta/epsilon subdivisions,2WMQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Flavodoxin-like fold	-	-	1.6.5.2	ko:K03809	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	FMN_red
REGS1_k127_4741386_41	202955.BBND01000026_gene3378	3.957e-11	69.0	COG2199@1|root,COG3706@2|Bacteria,1REBC@1224|Proteobacteria,1SQ27@1236|Gammaproteobacteria,3NK5S@468|Moraxellaceae	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_4741386_15	243231.GSU3429	1.485e-145	475.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42QMR@68525|delta/epsilon subdivisions,2WJSY@28221|Deltaproteobacteria,43S94@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN-2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_0172	Proton_antipo_M
REGS1_k127_4741386_8	243231.GSU3430	8.438e-219	688.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42MBQ@68525|delta/epsilon subdivisions,2X5HD@28221|Deltaproteobacteria,43T5M@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM-2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
REGS1_k127_4741386_37	1517416.IDAT_10430	1.421e-18	87.0	2E9PU@1|root,333W6@2|Bacteria,1N6VC@1224|Proteobacteria,1SCC9@1236|Gammaproteobacteria,2QH16@267893|Idiomarinaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_3
REGS1_k127_4741386_35	316067.Geob_0186	3.435e-40	149.0	COG2026@1|root,COG2026@2|Bacteria,1N80B@1224|Proteobacteria,437Y0@68525|delta/epsilon subdivisions,2WRY3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
REGS1_k127_4741386_25	269799.Gmet_2758	5.037e-91	301.0	2AUXR@1|root,2ZBPW@2|Bacteria,1RAID@1224|Proteobacteria,42QWQ@68525|delta/epsilon subdivisions,2WMRI@28221|Deltaproteobacteria,43T93@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4741386_3	316067.Geob_1273	2.778e-264	829.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,43SAU@69541|Desulfuromonadales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	nuoL-2	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
REGS1_k127_4741386_36	243231.GSU3432	5.955e-40	150.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK-2	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
REGS1_k127_4741386_31	316067.Geob_1271	1.902e-51	188.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,42SDZ@68525|delta/epsilon subdivisions,2WPXS@28221|Deltaproteobacteria,43SJU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ-2	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
REGS1_k127_4741386_23	243231.GSU3434	5.813e-95	312.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42R5T@68525|delta/epsilon subdivisions,2WMVQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
REGS1_k127_4741386_11	316067.Geob_1268	1.99e-176	557.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,43S1U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
REGS1_k127_4741386_4	269799.Gmet_0159	2.73e-250	786.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WIPN@28221|Deltaproteobacteria,43RZX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG-2	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
REGS1_k127_4741386_29	443143.GM18_2711	3.785e-59	212.0	COG0727@1|root,COG0727@2|Bacteria,1RCAS@1224|Proteobacteria,43BA4@68525|delta/epsilon subdivisions,2X8W3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
REGS1_k127_4741386_7	243231.GSU3441	1.087e-223	698.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,43SBB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_4763539_21	338966.Ppro_0043	2.623e-66	232.0	COG2755@1|root,COG2755@2|Bacteria,1RHDZ@1224|Proteobacteria,42SMX@68525|delta/epsilon subdivisions,2X62A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
REGS1_k127_4763539_35	879212.DespoDRAFT_00357	1.005e-12	72.0	29B04@1|root,2ZXZ2@2|Bacteria,1P8EC@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4763539_23	398767.Glov_2482	1.01e-59	211.0	COG0847@1|root,COG0847@2|Bacteria,1MV8Z@1224|Proteobacteria,42MQQ@68525|delta/epsilon subdivisions,2WK68@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	EXOIII	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
REGS1_k127_4763539_9	443143.GM18_1364	1.908e-148	479.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,43TJ7@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	PFAM beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
REGS1_k127_4763539_5	243231.GSU2049	1.498e-173	554.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,43TJH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
REGS1_k127_4763539_37	279714.FuraDRAFT_3127	3.712e-07	57.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Tfp pilus assembly protein	-	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
REGS1_k127_4763539_36	1201290.M902_1560	9.461e-08	61.0	2EU5D@1|root,33MN1@2|Bacteria,1NN7M@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4763539_0	243231.GSU2050	0.0	1480.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,43UIT@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
REGS1_k127_4763539_22	404380.Gbem_3344	2.156e-62	216.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	algA	-	2.7.7.13,5.3.1.8	ko:K00971,ko:K01809,ko:K16011	ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025	M00114,M00361,M00362	R00885,R01819	RC00002,RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	Cupin_2,FdtA,MannoseP_isomer,NTP_transferase
REGS1_k127_4763539_14	316067.Geob_1871	1.032e-125	410.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WKQ9@28221|Deltaproteobacteria,43TB8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
REGS1_k127_4763539_3	398767.Glov_2511	5.682e-216	672.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfk-1	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
REGS1_k127_4763539_4	316067.Geob_1870	4.777e-198	622.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,42MFN@68525|delta/epsilon subdivisions,2WIJE@28221|Deltaproteobacteria,43SUT@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rmlB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_4763539_8	243231.GSU2367	3.123e-162	534.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,42N34@68525|delta/epsilon subdivisions,2WJUD@28221|Deltaproteobacteria,43TYF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	iAF987.Gmet_2474	OstA,OstA_2,OstA_C
REGS1_k127_4763539_12	243231.GSU2368	2.398e-132	434.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,43U37@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Mur ligase, middle domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
REGS1_k127_4763539_10	243231.GSU2370	5.097e-138	443.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WP9B@28221|Deltaproteobacteria,43U3E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
REGS1_k127_4763539_18	316067.Geob_1866	1.745e-97	325.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,42N5B@68525|delta/epsilon subdivisions,2WJX4@28221|Deltaproteobacteria,43TZG@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
REGS1_k127_4763539_28	316067.Geob_1859	1.053e-47	177.0	COG0741@1|root,COG0741@2|Bacteria,1NUIE@1224|Proteobacteria,42ZRP@68525|delta/epsilon subdivisions,2WUW9@28221|Deltaproteobacteria,43UP9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
REGS1_k127_4763539_2	316067.Geob_1858	3.526e-226	704.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,43TSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_4763539_29	1122223.KB890700_gene2094	1.911e-44	165.0	COG2337@1|root,COG2337@2|Bacteria,1WMWG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
REGS1_k127_4763539_32	552811.Dehly_1563	3.218e-18	87.0	COG2336@1|root,COG2336@2|Bacteria,2G9F5@200795|Chloroflexi	200795|Chloroflexi	K	PFAM SpoVT AbrB domain protein	-	-	-	ko:K07172	-	-	-	-	ko00000,ko02048	-	-	-	MazE_antitoxin
REGS1_k127_4763539_25	269799.Gmet_2533	9.538e-54	189.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,42V2I@68525|delta/epsilon subdivisions,2WRI9@28221|Deltaproteobacteria,43VGH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM Addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
REGS1_k127_4763539_26	398767.Glov_1222	3.517e-51	182.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,42STB@68525|delta/epsilon subdivisions,2WP7C@28221|Deltaproteobacteria,43VS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_4763539_31	1123487.KB892844_gene852	1.796e-24	104.0	29RZY@1|root,30D49@2|Bacteria,1N736@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4763539_40	314262.MED193_14347	1.12e-05	53.0	29RZY@1|root,30D49@2|Bacteria,1N736@1224|Proteobacteria,2UUIX@28211|Alphaproteobacteria,2P4W4@2433|Roseobacter	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4763539_38	449673.BACSTE_01946	1.995e-06	50.0	COG3451@1|root,COG3451@2|Bacteria,4P2BT@976|Bacteroidetes,2FQ3P@200643|Bacteroidia,4APM6@815|Bacteroidaceae	976|Bacteroidetes	U	type IV secretory pathway VirB4	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4763539_33	338966.Ppro_1838	6.643e-17	82.0	2E8BS@1|root,332QF@2|Bacteria,1N9X2@1224|Proteobacteria,431DN@68525|delta/epsilon subdivisions,2WX5W@28221|Deltaproteobacteria,43VDY@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4763539_39	641491.DND132_1220	9.476e-06	56.0	2ARE9@1|root,31GQB@2|Bacteria,1QEDX@1224|Proteobacteria,43EE7@68525|delta/epsilon subdivisions,2X0FZ@28221|Deltaproteobacteria,2MC7I@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
REGS1_k127_4763539_13	338966.Ppro_3278	7.977e-126	407.0	COG0501@1|root,COG0501@2|Bacteria,1MUNA@1224|Proteobacteria,43BJA@68525|delta/epsilon subdivisions,2WME6@28221|Deltaproteobacteria,43TIC@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_4763539_20	269799.Gmet_2492	1.176e-85	288.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,42QQ3@68525|delta/epsilon subdivisions,2WNPH@28221|Deltaproteobacteria,43U0C@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
REGS1_k127_4763539_1	1121918.ARWE01000001_gene2332	4.818e-248	770.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,42MPB@68525|delta/epsilon subdivisions,2WJUV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_4763539_15	243231.GSU2380	1.269e-121	394.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,43S5I@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
REGS1_k127_4763539_19	926554.KI912636_gene3138	8.067e-97	321.0	COG0410@1|root,COG0410@2|Bacteria,1WM3P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
REGS1_k127_4763539_17	1337936.IJ00_17865	3.45e-99	329.0	COG0411@1|root,COG0411@2|Bacteria,1G3VI@1117|Cyanobacteria,1HJ77@1161|Nostocales	1117|Cyanobacteria	E	Amino acid amide ABC transporter ATP-binding protein 1, HAAT family	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_4763539_16	1489678.RDMS_13795	1.712e-108	373.0	COG4177@1|root,COG4177@2|Bacteria	2|Bacteria	E	L-phenylalanine transmembrane transporter activity	livM	-	-	ko:K01995,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
REGS1_k127_4763539_11	926554.KI912636_gene3135	8.164e-138	445.0	COG0559@1|root,COG0559@2|Bacteria,1WJ0D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_4763539_7	941449.dsx2_0111	3.906e-165	528.0	COG0683@1|root,COG0683@2|Bacteria,1N76S@1224|Proteobacteria,42RNG@68525|delta/epsilon subdivisions,2WNA9@28221|Deltaproteobacteria,2MASU@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_4763539_6	243231.GSU2381	2.421e-172	546.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,42NRG@68525|delta/epsilon subdivisions,2WJRU@28221|Deltaproteobacteria,43U0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2495	GATase,Glycos_trans_3N,Glycos_transf_3
REGS1_k127_4763539_27	398767.Glov_2543	1.465e-48	174.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QTS@68525|delta/epsilon subdivisions,2WN02@28221|Deltaproteobacteria,43TCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2496	GATase
REGS1_k127_4780641_16	765911.Thivi_2913	4e-115	383.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,1RM9Q@1236|Gammaproteobacteria,1WW1W@135613|Chromatiales	135613|Chromatiales	CP	Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit	-	-	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	-	Proton_antipo_M
REGS1_k127_4780641_5	398767.Glov_2560	2.316e-255	803.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria,43T2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	ehrA-2	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
REGS1_k127_4780641_14	269799.Gmet_2604	9.661e-117	379.0	COG1762@1|root,COG1762@2|Bacteria,1RG0Z@1224|Proteobacteria,42RSF@68525|delta/epsilon subdivisions,2WNXB@28221|Deltaproteobacteria,43W0H@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	-	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	HTH_17,PTS_EIIA_2
REGS1_k127_4780641_20	269799.Gmet_2603	6.001e-58	203.0	COG2337@1|root,COG2337@2|Bacteria,1N4YT@1224|Proteobacteria,42U3R@68525|delta/epsilon subdivisions,2WR09@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
REGS1_k127_4780641_2	269799.Gmet_2601	8.661e-299	928.0	COG0651@1|root,COG0651@2|Bacteria,1MXRW@1224|Proteobacteria,42NFV@68525|delta/epsilon subdivisions,2WJZ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	CP	PFAM NADH Ubiquinone plastoquinone (complex I)	ehrA-1	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M,Proton_antipo_N
REGS1_k127_4780641_10	269799.Gmet_2600	4.516e-161	512.0	COG0650@1|root,COG0650@2|Bacteria,1MXV5@1224|Proteobacteria,42NHI@68525|delta/epsilon subdivisions,2WJ3D@28221|Deltaproteobacteria,43T74@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH dehydrogenase	ehrB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0374,iAF987.Gmet_2600	NADHdh
REGS1_k127_4780641_18	269799.Gmet_2599	2.791e-109	356.0	COG4237@1|root,COG4237@2|Bacteria,1NAT8@1224|Proteobacteria,42NDW@68525|delta/epsilon subdivisions,2WMF0@28221|Deltaproteobacteria,43SXS@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	hydrogenase 4 membrane	ehrC	-	-	ko:K12140	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q2
REGS1_k127_4780641_4	269799.Gmet_2598	5.647e-273	846.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,42MG7@68525|delta/epsilon subdivisions,2WIRA@28221|Deltaproteobacteria,43TR1@69541|Desulfuromonadales	28221|Deltaproteobacteria	CP	Proton-conducting membrane transporter	ehrD	-	-	ko:K12141	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
REGS1_k127_4780641_3	269799.Gmet_2597	2.582e-281	869.0	COG0852@1|root,COG3261@1|root,COG0852@2|Bacteria,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,43SVB@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
REGS1_k127_4780641_11	269799.Gmet_2596	6.365e-134	429.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WJX8@28221|Deltaproteobacteria,43T9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	ehrS	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2596	Fer4,Fer4_7,Oxidored_q6
REGS1_k127_4780641_0	879212.DespoDRAFT_03300	0.0	1088.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,2MJ0S@213118|Desulfobacterales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_4780641_1	338966.Ppro_3603	9.608e-301	927.0	COG1866@1|root,COG1866@2|Bacteria,1MWXN@1224|Proteobacteria,42N5Y@68525|delta/epsilon subdivisions,2WJMT@28221|Deltaproteobacteria,43TB3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3169	PEPCK_ATP
REGS1_k127_4780641_6	316067.Geob_0681	3.509e-249	772.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,42M15@68525|delta/epsilon subdivisions,2WIQN@28221|Deltaproteobacteria,43T9E@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
REGS1_k127_4780641_21	316067.Geob_0682	1.165e-31	124.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,43VM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
REGS1_k127_4780641_17	243231.GSU3106	9.677e-111	361.0	COG1351@1|root,COG1351@2|Bacteria,1Q73I@1224|Proteobacteria,42N3X@68525|delta/epsilon subdivisions,2WN7U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	thyX	-	2.1.1.148	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	-	R06613	RC00022,RC00332	ko00000,ko00001,ko01000	-	-	-	Thy1
REGS1_k127_4780641_9	316067.Geob_0684	2.665e-163	518.0	COG3872@1|root,COG3872@2|Bacteria,1RCB0@1224|Proteobacteria,42R3I@68525|delta/epsilon subdivisions,2WMZR@28221|Deltaproteobacteria,43U2U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1385)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1385
REGS1_k127_4780641_8	398767.Glov_1029	6.588e-195	611.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_4780641_12	243231.GSU3103	1.751e-128	416.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,43TP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
REGS1_k127_4780641_7	243231.GSU3102	5.03e-223	697.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,43TD6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
REGS1_k127_4780641_15	338966.Ppro_3043	7.954e-116	376.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WNAZ@28221|Deltaproteobacteria,43TJ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
REGS1_k127_4780641_19	316067.Geob_3824	4.107e-67	232.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_4780641_13	316067.Geob_3823	8.376e-121	393.0	COG1179@1|root,COG1179@2|Bacteria,1MWXR@1224|Proteobacteria,42PHC@68525|delta/epsilon subdivisions,2WNBT@28221|Deltaproteobacteria,43T6J@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
REGS1_k127_4780641_22	443143.GM18_4401	3.154e-22	98.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,42PBB@68525|delta/epsilon subdivisions,2WKBZ@28221|Deltaproteobacteria,43UU7@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
REGS1_k127_4800556_37	243231.GSU0392	3.58e-33	134.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,43UXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_4800556_26	316067.Geob_0606	8.789e-66	228.0	COG3216@1|root,COG3216@2|Bacteria,1QEG2@1224|Proteobacteria,42VUY@68525|delta/epsilon subdivisions,2WQ90@28221|Deltaproteobacteria,43UUV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
REGS1_k127_4800556_12	404380.Gbem_3783	1.342e-117	383.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WPKC@28221|Deltaproteobacteria,43UBP@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
REGS1_k127_4800556_19	338966.Ppro_3582	1.506e-95	317.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,43SVY@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	metallopeptidase activity	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
REGS1_k127_4800556_13	443144.GM21_3627	1.586e-117	384.0	COG0702@1|root,COG0702@2|Bacteria,1MW54@1224|Proteobacteria,42PP6@68525|delta/epsilon subdivisions,2WJN2@28221|Deltaproteobacteria,43TRT@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	1.6.5.3,1.6.99.3	ko:K00329,ko:K00356	ko00190,map00190	-	R11945	RC00061	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10
REGS1_k127_4800556_7	443144.GM21_0983	1.61e-198	626.0	COG3303@1|root,COG3303@2|Bacteria,1P8CP@1224|Proteobacteria,42MXS@68525|delta/epsilon subdivisions,2WJ68@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Seven times multi-haem cytochrome CxxCH	-	-	-	-	-	-	-	-	-	-	-	-	Multi-haem_cyto
REGS1_k127_4800556_14	269799.Gmet_3150	1.294e-114	376.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,42P2E@68525|delta/epsilon subdivisions,2WIJQ@28221|Deltaproteobacteria,43TBK@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
REGS1_k127_4800556_35	443143.GM18_2691	1.472e-37	149.0	2ERCV@1|root,33IYH@2|Bacteria,1NPE7@1224|Proteobacteria,42X89@68525|delta/epsilon subdivisions,2WTHC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2889)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2889
REGS1_k127_4800556_16	545695.TREAZ_2132	4.022e-108	359.0	COG0618@1|root,COG0618@2|Bacteria,2J6KM@203691|Spirochaetes	203691|Spirochaetes	S	3'(2'),5'-bisphosphate nucleotidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4800556_4	269799.Gmet_3228	4.742e-230	727.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,42MB1@68525|delta/epsilon subdivisions,2WJ76@28221|Deltaproteobacteria,43UFQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
REGS1_k127_4800556_6	269799.Gmet_0385	3.337e-201	629.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,43TRH@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_4800556_17	269799.Gmet_0386	8.783e-108	351.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria,43SWF@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	imidazoleglycerol-phosphate dehydratase activity	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
REGS1_k127_4800556_15	404380.Gbem_3702	1.195e-111	367.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,42QX8@68525|delta/epsilon subdivisions,2WMNR@28221|Deltaproteobacteria,43TF4@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
REGS1_k127_4800556_11	443143.GM18_4150	2.396e-128	414.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2WK1K@28221|Deltaproteobacteria,43SU7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0388	His_biosynth
REGS1_k127_4800556_10	398767.Glov_1018	5.076e-146	465.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
REGS1_k127_4800556_32	316067.Geob_0694	5.581e-41	154.0	COG0140@1|root,COG0140@2|Bacteria,1QXPJ@1224|Proteobacteria,42S79@68525|delta/epsilon subdivisions,2X7FP@28221|Deltaproteobacteria,43SI3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	phosphoribosyl-ATP diphosphatase activity	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
REGS1_k127_4800556_31	443143.GM18_2631	1.895e-41	155.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,42TJR@68525|delta/epsilon subdivisions,2WRDG@28221|Deltaproteobacteria,43V3W@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
REGS1_k127_4800556_29	316067.Geob_1572	4.009e-47	170.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria,43V5K@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
REGS1_k127_4800556_25	316067.Geob_1573	1.401e-71	252.0	COG4241@1|root,COG4241@2|Bacteria,1N4XJ@1224|Proteobacteria,42QCS@68525|delta/epsilon subdivisions,2WKDT@28221|Deltaproteobacteria,43V0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2232
REGS1_k127_4800556_27	269799.Gmet_2841	2.627e-63	222.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,43V2Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
REGS1_k127_4800556_23	443143.GM18_3626	1.641e-76	257.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,42SGH@68525|delta/epsilon subdivisions,2WP2B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1897	PRA-CH,PRA-PH
REGS1_k127_4800556_9	316067.Geob_2088	1.37e-172	544.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,42N9N@68525|delta/epsilon subdivisions,2WIY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
REGS1_k127_4800556_24	765420.OSCT_2147	1.289e-72	255.0	COG0600@1|root,COG0600@2|Bacteria,2G837@200795|Chloroflexi	200795|Chloroflexi	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
REGS1_k127_4800556_22	292459.STH874	2.027e-84	287.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
REGS1_k127_4800556_20	204669.Acid345_0825	1.003e-92	317.0	COG0715@1|root,COG0715@2|Bacteria,3Y5UN@57723|Acidobacteria,2JNY2@204432|Acidobacteriia	204432|Acidobacteriia	P	NMT1-like family	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
REGS1_k127_4800556_40	588932.JHOF01000023_gene1920	1.327e-10	74.0	COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2V9VC@28211|Alphaproteobacteria,2KJJ6@204458|Caulobacterales	204458|Caulobacterales	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
REGS1_k127_4800556_21	243231.GSU0621	5.343e-89	304.0	COG1215@1|root,COG1215@2|Bacteria,1NFA4@1224|Proteobacteria,42WEV@68525|delta/epsilon subdivisions,2WS1J@28221|Deltaproteobacteria,43U0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3
REGS1_k127_4800556_36	398767.Glov_2781	3.389e-33	131.0	COG1186@1|root,COG1186@2|Bacteria,1NBAD@1224|Proteobacteria,42UTT@68525|delta/epsilon subdivisions,2WQZK@28221|Deltaproteobacteria,43VGU@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM Class I peptide chain release factor	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
REGS1_k127_4800556_2	243231.GSU0547	1.81e-247	788.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2WK5H@28221|Deltaproteobacteria,43U0Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
REGS1_k127_4800556_39	580332.Slit_0254	7.767e-12	74.0	COG1729@1|root,COG1729@2|Bacteria,1P69R@1224|Proteobacteria,2W622@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4800556_0	580332.Slit_0253	1.932e-292	938.0	COG0457@1|root,COG1305@1|root,COG3391@1|root,COG4733@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,1R42S@1224|Proteobacteria	1224|Proteobacteria	E	fibronectin type III domain protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_4800556_1	316067.Geob_0699	3.273e-279	868.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,43U19@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_4800556_8	243231.GSU3090	5.614e-197	629.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
REGS1_k127_4800556_28	316067.Geob_0697	2.501e-53	193.0	COG1286@1|root,COG1286@2|Bacteria,1RJE1@1224|Proteobacteria,42SCW@68525|delta/epsilon subdivisions,2WNJJ@28221|Deltaproteobacteria,43VIW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Colicin V production protein	-	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
REGS1_k127_4800556_38	443143.GM18_4147	2.632e-28	114.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,42V6T@68525|delta/epsilon subdivisions,2WRAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
REGS1_k127_4800556_3	316067.Geob_2294	5.164e-231	722.0	COG0017@1|root,COG0017@2|Bacteria,1MWFV@1224|Proteobacteria,42MJX@68525|delta/epsilon subdivisions,2WJDM@28221|Deltaproteobacteria,43TMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	PFAM tRNA synthetase, class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
REGS1_k127_4800556_18	243231.GSU0205	7.609e-103	337.0	COG1309@1|root,COG1309@2|Bacteria,1R52P@1224|Proteobacteria,42VHH@68525|delta/epsilon subdivisions,2WRQ2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Bacterial transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	TetR,TetR_N
REGS1_k127_4800556_5	243231.GSU0204	9.006e-223	697.0	COG1032@1|root,COG1032@2|Bacteria,1R92G@1224|Proteobacteria,42RM5@68525|delta/epsilon subdivisions,2WNP2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_4800556_34	316067.Geob_2510	7.561e-39	146.0	COG0778@1|root,COG2768@1|root,COG0778@2|Bacteria,COG2768@2|Bacteria,1R4E3@1224|Proteobacteria,42RVJ@68525|delta/epsilon subdivisions,2WNCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Nitroreductase
REGS1_k127_4902477_2	316067.Geob_1537	3.721e-83	279.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,43TSK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
REGS1_k127_4902477_0	269799.Gmet_1268	2.643e-253	784.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,42M5D@68525|delta/epsilon subdivisions,2WJ59@28221|Deltaproteobacteria,43SYE@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
REGS1_k127_4902477_1	398767.Glov_3166	1.701e-92	305.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,42RR2@68525|delta/epsilon subdivisions,2WNPQ@28221|Deltaproteobacteria,43TIT@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1269	Aconitase_C
REGS1_k127_4902477_5	756067.MicvaDRAFT_0815	3.952e-25	113.0	COG2931@1|root,COG2931@2|Bacteria,1G0ZC@1117|Cyanobacteria,1H8KD@1150|Oscillatoriales	1117|Cyanobacteria	Q	PFAM Hemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Calx-beta,Chlam_PMP,DUF4347,HemolysinCabind
REGS1_k127_4902477_7	768671.ThimaDRAFT_3167	8.469e-17	96.0	COG1361@1|root,COG3210@1|root,COG1361@2|Bacteria,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K12678	-	-	-	-	ko00000,ko02000,ko02044	1.B.12.1.1,1.B.12.1.3	-	-	DUF11,DUF4347,Flg_new,SLH,SdrD_B
REGS1_k127_4902477_3	316067.Geob_3253	1.43e-69	270.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_4902477_8	861299.J421_4147	1.087e-05	60.0	COG2319@1|root,COG4409@1|root,COG2319@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,F5_F8_type_C,TIR_2,WD40
REGS1_k127_4902477_6	1236541.BALL01000084_gene5032	6.618e-20	107.0	COG3637@1|root,COG3637@2|Bacteria,1R2XC@1224|Proteobacteria,1T5ZN@1236|Gammaproteobacteria,2QEKA@267890|Shewanellaceae	2|Bacteria	M	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB,OMP_b-brl,fn3
REGS1_k127_4902477_4	1121930.AQXG01000002_gene2352	1.592e-25	125.0	COG2373@1|root,COG2755@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG4412@1|root,COG4932@1|root,COG2373@2|Bacteria,COG2755@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG4412@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	pelX	-	-	ko:K07004,ko:K09955,ko:K16915,ko:K20276	ko02010,ko02024,map02010,map02024	M00246	-	-	ko00000,ko00001,ko00002,ko02000	-	-	-	Beta_helix,Laminin_G_3
REGS1_k127_4903032_0	316067.Geob_3147	8.801e-302	935.0	COG0236@1|root,COG1028@1|root,COG3321@1|root,COG0236@2|Bacteria,COG1028@2|Bacteria,COG3321@2|Bacteria,1R89Z@1224|Proteobacteria,42NGA@68525|delta/epsilon subdivisions,2WJK3@28221|Deltaproteobacteria,43W01@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	PFAM Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,FabA,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
REGS1_k127_4903032_1	443143.GM18_2127	9.873e-219	691.0	COG2070@1|root,COG2070@2|Bacteria,1MWMI@1224|Proteobacteria,42P2I@68525|delta/epsilon subdivisions,2WK0M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIGRFAM PfaD family protein	-	-	-	-	-	-	-	-	-	-	-	-	NMO
REGS1_k127_4903032_12	443143.GM18_3736	9.131e-59	206.0	COG1734@1|root,COG1734@2|Bacteria,1NH80@1224|Proteobacteria,42TPK@68525|delta/epsilon subdivisions,2X6N1@28221|Deltaproteobacteria,43UXV@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
REGS1_k127_4903032_6	443143.GM18_0272	8.545e-124	400.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WJUU@28221|Deltaproteobacteria,43SE9@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_4903032_8	316067.Geob_0410	7.698e-106	349.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,42RV7@68525|delta/epsilon subdivisions,2WNZT@28221|Deltaproteobacteria,43T28@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation	-	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
REGS1_k127_4903032_5	269799.Gmet_3385	3.222e-154	496.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,42S5J@68525|delta/epsilon subdivisions,2WNJC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_4903032_9	404380.Gbem_0241	2.591e-97	332.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,42NSS@68525|delta/epsilon subdivisions,2WIVV@28221|Deltaproteobacteria,43UAF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
REGS1_k127_4903032_11	316067.Geob_0413	5.713e-64	230.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,42R1A@68525|delta/epsilon subdivisions,2WMV6@28221|Deltaproteobacteria,43THD@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
REGS1_k127_4903032_7	243231.GSU0443	4.788e-121	398.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,42N0J@68525|delta/epsilon subdivisions,2WJFX@28221|Deltaproteobacteria,43TCP@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
REGS1_k127_4903032_4	243231.GSU0442	1.514e-180	570.0	COG1060@1|root,COG1060@2|Bacteria,1MX50@1224|Proteobacteria,42M6U@68525|delta/epsilon subdivisions,2WJ6Y@28221|Deltaproteobacteria,43UE4@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnC	-	1.21.98.1	ko:K11784	ko00130,ko01110,map00130,map01110	-	R08588	RC02329	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
REGS1_k127_4903032_3	525897.Dbac_2317	1.639e-181	576.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2WJP4@28221|Deltaproteobacteria,2MGF1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
REGS1_k127_4903032_2	269799.Gmet_3391	1.112e-181	573.0	COG1060@1|root,COG1060@2|Bacteria,1QN23@1224|Proteobacteria,42M6Z@68525|delta/epsilon subdivisions,2WJ4C@28221|Deltaproteobacteria,43SZF@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate	mqnE	-	1.21.98.1,2.5.1.120,2.5.1.77	ko:K11779,ko:K11784,ko:K18285	ko00130,ko00680,ko01110,ko01120,map00130,map00680,map01110,map01120	M00378	R08588,R09396,R10667	RC00021,RC01381,RC02329,RC03002,RC03007,RC03234	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3391	Radical_SAM
REGS1_k127_4903032_10	243231.GSU0440	1.214e-76	261.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,42QXP@68525|delta/epsilon subdivisions,2WP9I@28221|Deltaproteobacteria,43SFU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3392	Flavoprotein
REGS1_k127_4915766_2	1504672.669782768	2.938e-144	460.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VJI1@28216|Betaproteobacteria,4ADN0@80864|Comamonadaceae	28216|Betaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
REGS1_k127_4915766_0	443143.GM18_2013	0.0	1200.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42NHQ@68525|delta/epsilon subdivisions,2WJZ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM AMP-dependent synthetase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,NAD_binding_4,PP-binding,Sterile
REGS1_k127_4915766_1	237368.SCABRO_02350	4.385e-281	877.0	COG3852@1|root,COG3852@2|Bacteria,2J4Y6@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,Response_reg
REGS1_k127_4915766_5	269799.Gmet_1149	2.344e-22	101.0	2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,42X5E@68525|delta/epsilon subdivisions,2WSAR@28221|Deltaproteobacteria,43V86@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4915766_4	118005.AWNK01000007_gene739	1.715e-30	133.0	COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria	2|Bacteria	M	chlorophyll binding	oprF	GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944	-	ko:K03286,ko:K07275	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,OprF
REGS1_k127_4915766_3	1123248.KB893339_gene2701	3.088e-54	203.0	COG4932@1|root,COG5276@1|root,COG4932@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_1,Big_3_2,Big_3_5,Big_5,DUF3494
REGS1_k127_49287_30	552811.Dehly_0623	6.451e-25	109.0	COG3383@1|root,COG3383@2|Bacteria,2GAS8@200795|Chloroflexi,34D7W@301297|Dehalococcoidia	301297|Dehalococcoidia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4
REGS1_k127_49287_4	56780.SYN_00152	2.801e-182	587.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2MR61@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NADH ubiquinone oxidoreductase, NADH-binding	-	-	1.12.1.3,1.6.5.3	ko:K00124,ko:K00335,ko:K18331	ko00190,ko00630,ko00680,ko01100,ko01120,ko01200,map00190,map00630,map00680,map01100,map01120,map01200	M00144	R00519,R11945	RC00061,RC02796	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
REGS1_k127_49287_21	1499967.BAYZ01000171_gene5565	1.046e-78	274.0	COG1148@1|root,COG1905@1|root,COG1148@2|Bacteria,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	bamG	-	1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K00334,ko:K03388	ko00190,ko00680,ko01100,ko01120,ko01200,map00190,map00680,map01100,map01120,map01200	M00144,M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944,R11945	RC00011,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fer4,NAD_binding_8,Pyr_redox_2,Response_reg
REGS1_k127_49287_20	264732.Moth_0810	1.222e-85	292.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,42FS6@68295|Thermoanaerobacterales	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
REGS1_k127_49287_26	485916.Dtox_1351	1.038e-40	158.0	COG1150@1|root,COG1150@2|Bacteria,1V8UM@1239|Firmicutes,24J4U@186801|Clostridia,2622W@186807|Peptococcaceae	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8
REGS1_k127_49287_0	880072.Desac_1035	2.046e-320	1003.0	COG0067@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0070@2|Bacteria,1NZ4D@1224|Proteobacteria,43B3T@68525|delta/epsilon subdivisions,2X6HR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GXGXG motif	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GXGXG
REGS1_k127_49287_1	880072.Desac_1036	7.574e-194	618.0	COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
REGS1_k127_49287_9	706587.Desti_2948	7.154e-136	448.0	COG0069@1|root,COG0069@2|Bacteria	2|Bacteria	E	glutamate synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
REGS1_k127_49287_25	880072.Desac_0314	3.646e-56	207.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	-	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,MTHFR
REGS1_k127_49287_31	589924.Ferp_0839	7.03e-16	83.0	COG1908@1|root,arCOG02475@2157|Archaea,2XZDA@28890|Euryarchaeota,246CR@183980|Archaeoglobi	183980|Archaeoglobi	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	1.8.98.5,1.8.98.6	ko:K14127	ko00680,map00680	-	R00019,R11943,R11944	RC00011	ko00000,ko00001,ko01000	-	-	-	FlpD
REGS1_k127_49287_24	243231.GSU3354	2.702e-61	218.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,42W8P@68525|delta/epsilon subdivisions,2WRV4@28221|Deltaproteobacteria,43SM1@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
REGS1_k127_49287_13	316067.Geob_1078	3.217e-121	399.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,42PJJ@68525|delta/epsilon subdivisions,2WTZ5@28221|Deltaproteobacteria,43T0Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RluA family	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
REGS1_k127_49287_29	316067.Geob_0831	5.567e-32	145.0	COG4733@1|root,COG4733@2|Bacteria,1PF7Y@1224|Proteobacteria,437DU@68525|delta/epsilon subdivisions,2X2JZ@28221|Deltaproteobacteria,43VT0@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_49287_27	1499967.BAYZ01000093_gene4035	4.085e-39	158.0	28RXC@1|root,2ZE9F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_49287_28	1499967.BAYZ01000093_gene4035	2.453e-38	156.0	28RXC@1|root,2ZE9F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_49287_22	583355.Caka_2713	2.735e-70	263.0	COG4782@1|root,COG4782@2|Bacteria	2|Bacteria	P	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF900
REGS1_k127_49287_23	269799.Gmet_0207	6.898e-69	235.0	COG1051@1|root,COG1051@2|Bacteria,1MWNH@1224|Proteobacteria,42T59@68525|delta/epsilon subdivisions,2WPMV@28221|Deltaproteobacteria,43UZ6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	NUDIX
REGS1_k127_49287_2	316067.Geob_1126	4.492e-191	602.0	2C19K@1|root,33PMS@2|Bacteria,1NSP6@1224|Proteobacteria,42YKB@68525|delta/epsilon subdivisions,2WTSZ@28221|Deltaproteobacteria,43TR8@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_49287_32	316067.Geob_3045	9.603e-06	54.0	2DDAV@1|root,2ZHC8@2|Bacteria,1P8PH@1224|Proteobacteria,433GC@68525|delta/epsilon subdivisions,2WXB5@28221|Deltaproteobacteria,43VWN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
REGS1_k127_49287_11	243231.GSU0127	4.266e-127	412.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,43TI0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
REGS1_k127_49287_7	316067.Geob_2768	7.713e-159	515.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_49287_8	338963.Pcar_0819	7.866e-155	501.0	COG1921@1|root,COG1921@2|Bacteria,1MWXI@1224|Proteobacteria,42MU7@68525|delta/epsilon subdivisions,2WJFQ@28221|Deltaproteobacteria,43S0Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	selA	GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576	2.9.1.1	ko:K01042	ko00450,ko00970,map00450,map00970	-	R08219	RC01246	ko00000,ko00001,ko01000	-	-	-	Se-cys_synth_N,SelA
REGS1_k127_49287_17	316067.Geob_0562	1.117e-104	344.0	COG1802@1|root,COG1802@2|Bacteria,1MWG2@1224|Proteobacteria,42P4Y@68525|delta/epsilon subdivisions,2WM8E@28221|Deltaproteobacteria,43S47@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	regulatory protein GntR HTH	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
REGS1_k127_49287_3	269799.Gmet_0063	8.013e-186	585.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,42MW6@68525|delta/epsilon subdivisions,2WIYU@28221|Deltaproteobacteria,43STU@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Ion transport 2 domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
REGS1_k127_49287_18	243231.GSU3371	2.813e-103	342.0	COG1082@1|root,COG1082@2|Bacteria,1N8KJ@1224|Proteobacteria,42SR1@68525|delta/epsilon subdivisions,2WP5P@28221|Deltaproteobacteria,43TTK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
REGS1_k127_49287_12	338966.Ppro_3243	2.143e-126	410.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria,43T22@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
REGS1_k127_49287_5	443143.GM18_0561	4.754e-163	524.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2WJ9B@28221|Deltaproteobacteria,43SU2@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
REGS1_k127_49287_14	243231.GSU3374	5.099e-119	384.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,43U38@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
REGS1_k127_49287_16	316067.Geob_1093	1.029e-110	368.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,439XF@68525|delta/epsilon subdivisions,2X9PG@28221|Deltaproteobacteria,43SVQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_49287_10	443144.GM21_3447	1.281e-129	420.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria,43UB5@69541|Desulfuromonadales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_49287_15	443143.GM18_4429	1.707e-115	373.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
REGS1_k127_49287_19	316067.Geob_0374	2.069e-88	293.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,43T83@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Roadblock LC7 family protein	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
REGS1_k127_49287_6	398767.Glov_0368	8.051e-163	515.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria,43TSH@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	por	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
REGS1_k127_4935273_7	398767.Glov_2087	2.148e-54	194.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
REGS1_k127_4935273_3	443144.GM21_0924	2.29e-79	267.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WPEB@28221|Deltaproteobacteria,43W08@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_4935273_5	243231.GSU2704	4.253e-65	226.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,42SNY@68525|delta/epsilon subdivisions,2WP2P@28221|Deltaproteobacteria,43UQT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
REGS1_k127_4935273_4	269799.Gmet_1036	4.228e-65	236.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,42PGH@68525|delta/epsilon subdivisions,2WPJ6@28221|Deltaproteobacteria,43UQA@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Probable molybdopterin binding domain	moaB	-	2.7.7.75	ko:K03638,ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
REGS1_k127_4935273_2	243231.GSU3147	5.183e-80	279.0	COG0746@1|root,COG1763@1|root,COG0746@2|Bacteria,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,42RZK@68525|delta/epsilon subdivisions,2WQ3C@28221|Deltaproteobacteria,43SFT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
REGS1_k127_4935273_0	243231.GSU2491	6.729e-187	591.0	COG2271@1|root,COG2271@2|Bacteria,1QXP5@1224|Proteobacteria,43C51@68525|delta/epsilon subdivisions,2X7FD@28221|Deltaproteobacteria,43UVX@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_4935273_9	443144.GM21_2383	6.039e-28	117.0	COG3409@1|root,COG3409@2|Bacteria,1NGBF@1224|Proteobacteria	1224|Proteobacteria	M	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
REGS1_k127_4935273_6	1121918.ARWE01000001_gene685	1.125e-55	205.0	2ENGF@1|root,33G3Y@2|Bacteria,1P8WT@1224|Proteobacteria,43261@68525|delta/epsilon subdivisions,2WXJG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4935273_1	243231.GSU1997	4.723e-176	563.0	COG1625@1|root,COG1625@2|Bacteria,1R76F@1224|Proteobacteria,42PNQ@68525|delta/epsilon subdivisions,2WKT9@28221|Deltaproteobacteria,43SDY@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
REGS1_k127_4935273_8	269799.Gmet_2051	3.118e-33	129.0	COG1923@1|root,COG1923@2|Bacteria,1QSI0@1224|Proteobacteria,42UHR@68525|delta/epsilon subdivisions,2WQKN@28221|Deltaproteobacteria,43VH7@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
REGS1_k127_5019858_0	398767.Glov_1472	6.809e-142	460.0	COG4591@1|root,COG4591@2|Bacteria,1QVSQ@1224|Proteobacteria,43BSZ@68525|delta/epsilon subdivisions,2WME9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
REGS1_k127_5019858_3	398767.Glov_1473	4.107e-24	104.0	2E5GP@1|root,3308B@2|Bacteria,1N858@1224|Proteobacteria,42VD7@68525|delta/epsilon subdivisions,2WSFR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5019858_2	443143.GM18_1597	5.893e-48	188.0	COG5164@1|root,COG5164@2|Bacteria,1NIMU@1224|Proteobacteria,43309@68525|delta/epsilon subdivisions,2WY60@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5019858_1	243231.GSU1685	1.538e-61	216.0	COG2206@1|root,COG2206@2|Bacteria,1REAA@1224|Proteobacteria,42S1X@68525|delta/epsilon subdivisions,2WNGR@28221|Deltaproteobacteria,43SIV@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Metal-dependent phosphohydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
REGS1_k127_5033320_4	269799.Gmet_0292	5.156e-103	373.0	COG4412@1|root,COG4932@1|root,COG4412@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5033320_0	316067.Geob_3682	7.703e-314	969.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,43TNF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
REGS1_k127_5033320_2	269799.Gmet_0103	7.983e-190	603.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,42N3K@68525|delta/epsilon subdivisions,2WIMV@28221|Deltaproteobacteria,43SUA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042,ko:K11528	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
REGS1_k127_5033320_10	243231.GSU0272	1.861e-56	202.0	COG3266@1|root,COG3266@2|Bacteria,1N9VA@1224|Proteobacteria,42VXQ@68525|delta/epsilon subdivisions,2WSBF@28221|Deltaproteobacteria,43UX6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5033320_1	269799.Gmet_0101	4.563e-196	630.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,42V17@68525|delta/epsilon subdivisions,2WRD3@28221|Deltaproteobacteria,43U6Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_5033320_3	316067.Geob_0291	6.171e-166	527.0	COG3266@1|root,COG3266@2|Bacteria,1RDC1@1224|Proteobacteria,42UDQ@68525|delta/epsilon subdivisions,2WTX3@28221|Deltaproteobacteria,43SY3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5033320_11	443143.GM18_2702	5.205e-40	153.0	COG2832@1|root,COG2832@2|Bacteria,1N7BI@1224|Proteobacteria,42VV6@68525|delta/epsilon subdivisions,2WS0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
REGS1_k127_5033320_12	391612.CY0110_04483	6.011e-26	115.0	COG0398@1|root,COG0398@2|Bacteria,1G6GT@1117|Cyanobacteria,3KJS0@43988|Cyanothece	1117|Cyanobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_5033320_5	443143.GM18_2279	3.037e-94	312.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,42R4C@68525|delta/epsilon subdivisions,2WKG9@28221|Deltaproteobacteria,43S01@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM LemA family protein	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
REGS1_k127_5033320_6	316067.Geob_3134	7.979e-90	304.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,42R0Q@68525|delta/epsilon subdivisions,2WN87@28221|Deltaproteobacteria,43S55@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
REGS1_k127_5033320_9	243231.GSU1479	5.63e-77	263.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,42UTC@68525|delta/epsilon subdivisions,2WR18@28221|Deltaproteobacteria,43SEP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam:TPM	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
REGS1_k127_5033320_13	1121930.AQXG01000002_gene1988	7.781e-16	90.0	COG0739@1|root,COG0739@2|Bacteria,4NPNT@976|Bacteroidetes	976|Bacteroidetes	M	peptidase M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_5033320_8	909663.KI867150_gene337	1.692e-81	289.0	COG0823@1|root,COG0823@2|Bacteria,1Q2D4@1224|Proteobacteria,437ZF@68525|delta/epsilon subdivisions,2X39G@28221|Deltaproteobacteria,2MSI3@213462|Syntrophobacterales	28221|Deltaproteobacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5033320_7	398767.Glov_0247	2.682e-87	293.0	COG1974@1|root,COG3467@1|root,COG1974@2|Bacteria,COG3467@2|Bacteria,1NE17@1224|Proteobacteria,42V3K@68525|delta/epsilon subdivisions,2WSAM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	pyridoxamine 5-phosphate oxidase-related	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
REGS1_k127_5033321_5	1232410.KI421421_gene3559	4.425e-06	49.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,42N3M@68525|delta/epsilon subdivisions,2WKM7@28221|Deltaproteobacteria,43U4T@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	nifR3	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
REGS1_k127_5033321_2	269799.Gmet_2562	4.973e-151	486.0	COG3852@1|root,COG3852@2|Bacteria,1NTTH@1224|Proteobacteria,42MC9@68525|delta/epsilon subdivisions,2WIYS@28221|Deltaproteobacteria,43T97@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation master sensor histidine kinase, PAS domain-containing	gnfL	-	2.7.13.3	ko:K02668,ko:K07708,ko:K07709	ko02020,map02020	M00497,M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_8
REGS1_k127_5033321_0	269799.Gmet_2563	1.379e-234	733.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43U5W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	gnfM	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_5033321_3	398767.Glov_1453	1.126e-21	103.0	COG3055@1|root,COG4932@1|root,COG3055@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,Big_3_3
REGS1_k127_5033321_1	398767.Glov_2227	1.225e-189	600.0	2ET0U@1|root,33KJ2@2|Bacteria,1N1U3@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5033321_4	383372.Rcas_1958	1.806e-09	60.0	COG2250@1|root,COG2250@2|Bacteria	2|Bacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
REGS1_k127_5069941_1	765914.ThisiDRAFT_2539	5.157e-180	579.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1R1TJ@1224|Proteobacteria,1T5AK@1236|Gammaproteobacteria,1X0V8@135613|Chromatiales	135613|Chromatiales	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_5069941_7	323261.Noc_2177	2.055e-55	205.0	COG1216@1|root,COG1216@2|Bacteria,1QTEK@1224|Proteobacteria,1S5EC@1236|Gammaproteobacteria,1WZPW@135613|Chromatiales	135613|Chromatiales	S	PFAM Glycosyl transferase family 2	-	-	-	ko:K12990	ko02024,ko02025,map02024,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
REGS1_k127_5069941_3	694427.Palpr_3037	2.328e-118	385.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	ubiG	-	-	ko:K15257	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_23,Methyltransf_25
REGS1_k127_5069941_6	871968.DESME_14380	4.217e-66	236.0	COG0463@1|root,COG0463@2|Bacteria,1V2EP@1239|Firmicutes,24GAY@186801|Clostridia	186801|Clostridia	M	group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_5069941_8	1168034.FH5T_21700	1.366e-54	199.0	COG1215@1|root,COG1215@2|Bacteria,4NNFI@976|Bacteroidetes,2FSV3@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_5069941_4	589865.DaAHT2_0371	5.461e-108	356.0	COG0463@1|root,COG0463@2|Bacteria,1QVXC@1224|Proteobacteria	1224|Proteobacteria	M	Pfam Glycosyl transferase family 2	wcaE	-	-	ko:K13683	-	-	-	-	ko00000,ko01000,ko01003	-	GT2	-	Glycos_transf_2
REGS1_k127_5069941_2	269799.Gmet_0730	1.829e-162	514.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,42M2W@68525|delta/epsilon subdivisions,2WJBV@28221|Deltaproteobacteria,43TQR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,CoA_binding,Ligase_CoA
REGS1_k127_5069941_0	316067.Geob_0762	3.119e-222	692.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,42M5K@68525|delta/epsilon subdivisions,2WJTS@28221|Deltaproteobacteria,43T89@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
REGS1_k127_5069941_5	316067.Geob_3347	2.078e-106	361.0	COG5184@1|root,COG5184@2|Bacteria,1QX3H@1224|Proteobacteria	1224|Proteobacteria	DZ	regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like
REGS1_k127_5284397_5	398767.Glov_1472	1.257e-103	342.0	COG4591@1|root,COG4591@2|Bacteria,1QVSQ@1224|Proteobacteria,43BSZ@68525|delta/epsilon subdivisions,2WME9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
REGS1_k127_5284397_7	398767.Glov_1471	2.106e-87	294.0	COG1136@1|root,COG1136@2|Bacteria,1PFRW@1224|Proteobacteria,42P38@68525|delta/epsilon subdivisions,2WMS9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_5284397_6	398767.Glov_1470	1.845e-100	340.0	28K4S@1|root,2Z9TM@2|Bacteria,1N4AQ@1224|Proteobacteria,42PSN@68525|delta/epsilon subdivisions,2WNF4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5284397_2	1121918.ARWE01000001_gene1756	3.722e-177	566.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42NMK@68525|delta/epsilon subdivisions,2WK6K@28221|Deltaproteobacteria,43U00@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_5284397_8	1121918.ARWE01000001_gene1757	2.132e-85	301.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,43U1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
REGS1_k127_5284397_9	398767.Glov_1481	4.103e-78	268.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
REGS1_k127_5284397_0	404380.Gbem_1015	2.198e-241	750.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	metY-1	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_5284397_1	443144.GM21_3246	1.49e-203	644.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,43STY@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM glycoside hydrolase, family 77	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
REGS1_k127_5284397_4	269799.Gmet_1442	9.005e-108	362.0	COG0655@1|root,COG0655@2|Bacteria,1RCHP@1224|Proteobacteria,42RCP@68525|delta/epsilon subdivisions,2WU98@28221|Deltaproteobacteria,43UDC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_5284397_10	1267534.KB906759_gene1980	2.312e-20	100.0	COG5552@1|root,COG5552@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2277)	MA20_01405	-	-	-	-	-	-	-	-	-	-	-	DUF2277
REGS1_k127_5284397_3	443143.GM18_4076	3.665e-166	539.0	COG4269@1|root,COG4269@2|Bacteria	2|Bacteria	T	membrane	yjgN	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF898
REGS1_k127_5292734_12	767817.Desgi_0556	1.423e-24	108.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,260BK@186807|Peptococcaceae	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
REGS1_k127_5292734_14	443143.GM18_1597	6.874e-08	60.0	COG5164@1|root,COG5164@2|Bacteria,1NIMU@1224|Proteobacteria,43309@68525|delta/epsilon subdivisions,2WY60@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5292734_5	443143.GM18_2037	4.549e-92	306.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,42PAE@68525|delta/epsilon subdivisions,2WMA9@28221|Deltaproteobacteria,43TI8@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	-	-	-	-	-	-	-	-	-	LysE
REGS1_k127_5292734_0	269799.Gmet_1637	0.0	1292.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,42MDI@68525|delta/epsilon subdivisions,2WIVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	malic protein domain protein	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1637	Malic_M,PTA_PTB,malic
REGS1_k127_5292734_6	316067.Geob_2880	7.893e-88	300.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,43BAY@68525|delta/epsilon subdivisions,2X6Q4@28221|Deltaproteobacteria,43W1H@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1639	ROK
REGS1_k127_5292734_8	243231.GSU1474	7.906e-81	274.0	COG0586@1|root,COG0586@2|Bacteria,1NBBA@1224|Proteobacteria,42MFR@68525|delta/epsilon subdivisions,2WR9B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
REGS1_k127_5292734_7	859657.RPSI07_2666	5.436e-87	290.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,1K0BA@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
REGS1_k127_5292734_3	443143.GM18_1435	2.856e-161	514.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43T8C@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	degT	-	2.6.1.98	ko:K13017	ko00520,map00520	-	R10141	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_5292734_11	269799.Gmet_1764	1.621e-38	146.0	COG1534@1|root,COG1534@2|Bacteria,1Q1J9@1224|Proteobacteria,42WJ8@68525|delta/epsilon subdivisions,2WRWD@28221|Deltaproteobacteria,43V6M@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	CRS1_YhbY	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
REGS1_k127_5292734_13	269799.Gmet_3170	5.159e-18	84.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	frx-6	-	-	ko:K05337	-	-	-	-	ko00000	-	-	iAF987.Gmet_0148,iAF987.Gmet_3170	Fer4_13
REGS1_k127_5292734_2	316067.Geob_3282	3.745e-186	588.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,42P1T@68525|delta/epsilon subdivisions,2WKZB@28221|Deltaproteobacteria,43U36@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	-	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
REGS1_k127_5292734_4	243231.GSU1245	1.165e-137	447.0	COG0191@1|root,COG0191@2|Bacteria	2|Bacteria	G	fructose-bisphosphate aldolase activity	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase,OprB,SLH
REGS1_k127_5292734_10	443143.GM18_1715	6.418e-42	162.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,43V74@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Pfam:Methyltransf_26	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
REGS1_k127_5292734_9	316067.Geob_3284	1.558e-75	256.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,43UMR@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_5292734_1	269799.Gmet_2078	2.313e-270	833.0	COG0436@1|root,COG0436@2|Bacteria,1QW10@1224|Proteobacteria,42MQA@68525|delta/epsilon subdivisions,2WJDK@28221|Deltaproteobacteria,43S5R@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	bamJ	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
REGS1_k127_5344553_3	443143.GM18_1596	4.178e-41	153.0	COG0677@1|root,COG0677@2|Bacteria,1QV0P@1224|Proteobacteria,43BN8@68525|delta/epsilon subdivisions,2WTPE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	UDP binding domain	-	-	1.1.1.336	ko:K02472	ko00520,ko05111,map00520,map05111	-	R03317	RC00291	ko00000,ko00001,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
REGS1_k127_5344553_1	443143.GM18_1436	1.532e-190	597.0	COG0451@1|root,COG0451@2|Bacteria,1MVI8@1224|Proteobacteria,43AN9@68525|delta/epsilon subdivisions,2WJH6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_5344553_0	443143.GM18_1437	4.771e-225	700.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_5344553_2	443143.GM18_1438	9.755e-124	400.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
REGS1_k127_5438873_3	7955.ENSDARP00000098431	1.824e-51	197.0	KOG3544@1|root,KOG3544@2759|Eukaryota,39561@33154|Opisthokonta,3BC3Q@33208|Metazoa,3CWAU@33213|Bilateria,48APU@7711|Chordata,495XY@7742|Vertebrata,4A2I9@7898|Actinopterygii	33208|Metazoa	W	Thrombospondin-type laminin G domain and EAR	TSPEAR	GO:0003008,GO:0005575,GO:0005623,GO:0005886,GO:0005929,GO:0007600,GO:0007605,GO:0008150,GO:0009986,GO:0016020,GO:0031090,GO:0031253,GO:0032420,GO:0032421,GO:0032501,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0044422,GO:0044425,GO:0044441,GO:0044459,GO:0044463,GO:0044464,GO:0050877,GO:0050954,GO:0060170,GO:0071944,GO:0097458,GO:0098588,GO:0098590,GO:0098858,GO:0098862,GO:0120025,GO:0120038	-	-	-	-	-	-	-	-	-	-	EPTP,Laminin_G_2
REGS1_k127_5438873_7	314345.SPV1_04398	5.451e-10	71.0	COG0457@1|root,COG0457@2|Bacteria,1NI26@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2,DUF560,TPR_16,TPR_19,TPR_8
REGS1_k127_5438873_2	1173028.ANKO01000017_gene203	8.492e-93	307.0	COG0693@1|root,COG0693@2|Bacteria,1G301@1117|Cyanobacteria,1H8X8@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM ThiJ PfpI	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
REGS1_k127_5438873_5	667015.Bacsa_1846	9.614e-22	98.0	COG1917@1|root,COG1917@2|Bacteria,4P2Z6@976|Bacteroidetes	976|Bacteroidetes	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_5438873_4	1121094.KB894658_gene2598	3.751e-24	115.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,2G2PJ@200643|Bacteroidia,4AQG4@815|Bacteroidaceae	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_5438873_6	666681.M301_1470	1.776e-10	68.0	2CH72@1|root,32ZK4@2|Bacteria,1N8YD@1224|Proteobacteria,2VVUJ@28216|Betaproteobacteria,2KN4M@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Protein of unknown function (DUF2878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2878
REGS1_k127_5438873_0	1499967.BAYZ01000017_gene6238	1.252e-174	564.0	COG0028@1|root,COG0028@2|Bacteria,2NNMW@2323|unclassified Bacteria	2|Bacteria	EH	thiamine pyrophosphate protein TPP binding domain protein	ilvB1	GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
REGS1_k127_5438873_1	1499967.BAYZ01000017_gene6233	5.725e-112	366.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,ThiJ_like
REGS1_k127_5581648_2	269799.Gmet_1893	4.869e-198	632.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,42NKH@68525|delta/epsilon subdivisions,2WJ30@28221|Deltaproteobacteria,43T98@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5,3.6.4.12	ko:K03582,ko:K16898	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
REGS1_k127_5581648_1	269799.Gmet_1892	3.729e-206	656.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42NRK@68525|delta/epsilon subdivisions,2WIM6@28221|Deltaproteobacteria,43TAV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
REGS1_k127_5581648_44	1278073.MYSTI_07079	3.511e-06	61.0	2AQ29@1|root,31F7C@2|Bacteria,1NHC1@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5581648_36	1116472.MGMO_94c00380	1.319e-19	95.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,1S343@1236|Gammaproteobacteria,1XFAM@135618|Methylococcales	135618|Methylococcales	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_5581648_5	316067.Geob_1355	3.68e-164	540.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42M22@68525|delta/epsilon subdivisions,2WM8F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Chemotaxis sensory transducer	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal,PAS_4,dCache_1
REGS1_k127_5581648_17	641491.DND132_1571	4.103e-68	244.0	COG0607@1|root,COG0607@2|Bacteria,1RM2N@1224|Proteobacteria,43093@68525|delta/epsilon subdivisions,2WVD8@28221|Deltaproteobacteria,2M8VF@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_5581648_4	396595.TK90_1538	1.645e-180	572.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RRXR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	ATPase, AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
REGS1_k127_5581648_31	1283300.ATXB01000001_gene1441	3.727e-28	118.0	COG4249@1|root,COG4249@2|Bacteria,1R3WZ@1224|Proteobacteria,1SHF5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14
REGS1_k127_5581648_42	697282.Mettu_2652	2.278e-07	55.0	28SSJ@1|root,32U2Q@2|Bacteria,1N5WQ@1224|Proteobacteria,1SAGG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442,HTH_31
REGS1_k127_5581648_43	269799.Gmet_2591	2.807e-06	51.0	COG4226@1|root,COG4226@2|Bacteria,1MZYR@1224|Proteobacteria,42UGZ@68525|delta/epsilon subdivisions,2WR2B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	HicB family	-	-	-	-	-	-	-	-	-	-	-	-	HicB
REGS1_k127_5581648_24	439235.Dalk_3867	3.814e-46	171.0	COG3547@1|root,COG3547@2|Bacteria,1NCHY@1224|Proteobacteria,42TM4@68525|delta/epsilon subdivisions,2WR4U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_5581648_32	686340.Metal_2425	4.317e-26	111.0	2DXHE@1|root,3451P@2|Bacteria,1P3C9@1224|Proteobacteria,1SRS6@1236|Gammaproteobacteria,1XGRM@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5581648_38	278963.ATWD01000001_gene2097	5.641e-17	86.0	2ESFT@1|root,33K0K@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5581648_22	765910.MARPU_09605	1.187e-51	186.0	COG1598@1|root,COG1598@2|Bacteria,1RIRX@1224|Proteobacteria,1T0GC@1236|Gammaproteobacteria,1WZSD@135613|Chromatiales	135613|Chromatiales	S	HicB_like antitoxin of bacterial toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
REGS1_k127_5581648_29	202956.BBNL01000011_gene2417	4.93e-29	121.0	COG1724@1|root,COG1724@2|Bacteria,1N7S3@1224|Proteobacteria,1SHY4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
REGS1_k127_5581648_37	443144.GM21_3363	2.174e-17	94.0	COG0265@1|root,COG0265@2|Bacteria,1QXND@1224|Proteobacteria,42S6R@68525|delta/epsilon subdivisions,2WNAX@28221|Deltaproteobacteria,43VDV@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5581648_11	1396858.Q666_10270	5.364e-91	304.0	COG1814@1|root,COG1814@2|Bacteria,1MUZE@1224|Proteobacteria,1S2G7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
REGS1_k127_5581648_46	1219375.CM002139_gene172	0.0001518	55.0	COG0457@1|root,COG0726@1|root,COG4249@1|root,COG0457@2|Bacteria,COG0726@2|Bacteria,COG4249@2|Bacteria,1NE0A@1224|Proteobacteria,1SGXZ@1236|Gammaproteobacteria,1X38G@135614|Xanthomonadales	135614|Xanthomonadales	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,Polysacc_deac_1,Sel1,TPR_11,TPR_16,TPR_2,TPR_8
REGS1_k127_5581648_40	1224136.AMFN01000011_gene1937	1.21e-08	64.0	COG3637@1|root,COG3637@2|Bacteria,1NC4E@1224|Proteobacteria,1S9VJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Opacity family porin protein	tia	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
REGS1_k127_5581648_39	870187.Thini_2802	4.765e-14	74.0	COG0864@1|root,COG0864@2|Bacteria,1NJ2M@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5581648_23	99598.Cal7507_5431	1.999e-47	173.0	COG2337@1|root,COG2337@2|Bacteria,1G7P3@1117|Cyanobacteria,1HPNZ@1161|Nostocales	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
REGS1_k127_5581648_47	338966.Ppro_2181	0.0002921	53.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,42R97@68525|delta/epsilon subdivisions,2WMRA@28221|Deltaproteobacteria,43TIH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
REGS1_k127_5581648_45	41431.PCC8801_1565	0.000127	55.0	COG0457@1|root,COG0457@2|Bacteria,1G3N9@1117|Cyanobacteria,3KJT9@43988|Cyanothece	1117|Cyanobacteria	S	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_8
REGS1_k127_5581648_12	316067.Geob_1087	1.358e-82	288.0	COG0681@1|root,COG0681@2|Bacteria	2|Bacteria	U	signal peptide processing	-	-	3.4.21.89	ko:K13280	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
REGS1_k127_5581648_9	640081.Dsui_0999	1.018e-120	394.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,2KW6R@206389|Rhodocyclales	206389|Rhodocyclales	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_5581648_18	640081.Dsui_1000	9.938e-65	237.0	COG1721@1|root,COG1721@2|Bacteria	2|Bacteria	E	protein (some members contain a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_5581648_21	1298593.TOL_0293	1.28e-57	226.0	COG1305@1|root,COG1305@2|Bacteria,1PXA0@1224|Proteobacteria,1SS20@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
REGS1_k127_5581648_10	269799.Gmet_0855	3.494e-119	391.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43TNS@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
REGS1_k127_5581648_0	316067.Geob_0847	2.117e-313	970.0	COG0475@1|root,COG0490@1|root,COG1226@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,42MEM@68525|delta/epsilon subdivisions,2WK23@28221|Deltaproteobacteria,43T1F@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K03455,ko:K11747	-	-	-	-	ko00000,ko02000	2.A.37,2.A.37.1.2	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
REGS1_k127_5581648_25	316067.Geob_1947	2.49e-44	164.0	COG1993@1|root,COG1993@2|Bacteria,1N0EM@1224|Proteobacteria,42TZK@68525|delta/epsilon subdivisions,2WQ2E@28221|Deltaproteobacteria,43SQ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	CBS,DUF190
REGS1_k127_5581648_34	1304874.JAFY01000007_gene2174	1.676e-21	102.0	COG1309@1|root,COG1309@2|Bacteria,3TBT4@508458|Synergistetes	508458|Synergistetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_5581648_19	269799.Gmet_0359	2.025e-62	217.0	COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria,42X27@68525|delta/epsilon subdivisions,2WTCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
REGS1_k127_5581648_26	269799.Gmet_0360	2.158e-42	158.0	2CMJ1@1|root,32SEX@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1904)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1904
REGS1_k127_5581648_7	269799.Gmet_1034	4.442e-156	503.0	COG0282@1|root,COG0282@2|Bacteria,1MW61@1224|Proteobacteria,42MJA@68525|delta/epsilon subdivisions,2WJBJ@28221|Deltaproteobacteria,43T2K@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1034	Acetate_kinase
REGS1_k127_5581648_15	1232410.KI421412_gene383	2.283e-70	243.0	COG0778@1|root,COG0778@2|Bacteria,1RECN@1224|Proteobacteria,43DS9@68525|delta/epsilon subdivisions,2WNXD@28221|Deltaproteobacteria,43TGM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_5581648_3	338966.Ppro_1335	3.611e-188	595.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WJ7X@28221|Deltaproteobacteria,43UA0@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	TIGRFAM branched-chain amino acid aminotransferase	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_2853	Aminotran_4
REGS1_k127_5581648_14	338966.Ppro_0308	2.164e-70	244.0	COG2110@1|root,COG2110@2|Bacteria,1RCWP@1224|Proteobacteria,42RVP@68525|delta/epsilon subdivisions,2WNCX@28221|Deltaproteobacteria,43UUG@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Appr-1-p processing domain protein	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
REGS1_k127_5581648_27	269799.Gmet_2635	3.337e-35	141.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42UHF@68525|delta/epsilon subdivisions,2WQ7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
REGS1_k127_5581648_33	243231.GSU1042	1.239e-22	105.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_5581648_16	398767.Glov_2364	2.718e-70	244.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria	1224|Proteobacteria	S	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP	acpH	GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008081,GO:0008150,GO:0008152,GO:0008610,GO:0008770,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:0140096,GO:1901576	3.1.4.14	ko:K08682	ko00770,map00770	-	R01623	-	ko00000,ko00001,ko01000	-	-	iAPECO1_1312.APECO1_1606,iE2348C_1286.E2348C_0339,iECNA114_1301.ECNA114_0381,iECOK1_1307.ECOK1_0384,iECS88_1305.ECS88_0399,iECSF_1327.ECSF_0364,iPC815.YPO3193,iUMN146_1321.UM146_15340,iUTI89_1310.UTI89_C0426	ACP_PD
REGS1_k127_5581648_35	316067.Geob_2547	9.354e-20	94.0	COG3089@1|root,COG3089@2|Bacteria	2|Bacteria	S	Uncharacterised protein family (UPF0270)	yheU	-	-	ko:K07019,ko:K09898	-	-	-	-	ko00000	-	-	-	UPF0270
REGS1_k127_5581648_28	338966.Ppro_0544	4.01e-31	124.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,42VGM@68525|delta/epsilon subdivisions,2WSQ6@28221|Deltaproteobacteria,43VCV@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
REGS1_k127_5581648_13	404380.Gbem_1480	3.751e-72	245.0	COG0590@1|root,COG0590@2|Bacteria,1RE8P@1224|Proteobacteria,42RF7@68525|delta/epsilon subdivisions,2WNMP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	FJ	PFAM CMP dCMP deaminase zinc-binding	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
REGS1_k127_5581648_8	398767.Glov_0095	6.967e-149	482.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,42NA4@68525|delta/epsilon subdivisions,2WIJM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_5581648_20	316067.Geob_2609	1.592e-59	211.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,43V81@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
REGS1_k127_5581648_30	269799.Gmet_1597	1.327e-28	115.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
REGS1_k127_5581648_6	269799.Gmet_1598	9.068e-164	519.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2WIXX@28221|Deltaproteobacteria,43T0B@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
REGS1_k127_5649797_5	316067.Geob_3164	1.713e-150	498.0	2AIHE@1|root,318Z9@2|Bacteria,1NWQ1@1224|Proteobacteria,42ZTQ@68525|delta/epsilon subdivisions,2WV9Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5649797_6	316067.Geob_3165	2.437e-127	422.0	COG3391@1|root,COG3391@2|Bacteria,1R7E0@1224|Proteobacteria,42XD8@68525|delta/epsilon subdivisions,2WSJC@28221|Deltaproteobacteria,43VUI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM 40-residue YVTN family beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
REGS1_k127_5649797_4	316067.Geob_3166	1.139e-161	520.0	28WYN@1|root,33TG0@2|Bacteria,1NTYC@1224|Proteobacteria,42YTU@68525|delta/epsilon subdivisions,2WU4Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	6 heme-binding sites	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5649797_10	316067.Geob_3167	4.087e-99	332.0	COG3391@1|root,COG3391@2|Bacteria,1NW4P@1224|Proteobacteria,42Z3T@68525|delta/epsilon subdivisions,2WV9X@28221|Deltaproteobacteria,43VSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_5649797_11	316067.Geob_3168	1.126e-96	332.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42ZM6@68525|delta/epsilon subdivisions,2WV3N@28221|Deltaproteobacteria,43S9F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Member of a two-component regulatory system	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA
REGS1_k127_5649797_9	316067.Geob_3169	2.811e-101	333.0	COG0745@1|root,COG0745@2|Bacteria,1MU67@1224|Proteobacteria,42N90@68525|delta/epsilon subdivisions,2WUX8@28221|Deltaproteobacteria,43VZZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Heavy metal transcriptional response regulator	czcR	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_5649797_2	338966.Ppro_0610	1.505e-308	953.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,43UI2@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
REGS1_k127_5649797_8	269799.Gmet_2437	1.053e-115	376.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_5649797_0	398767.Glov_3227	0.0	1305.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
REGS1_k127_5649797_15	443143.GM18_1717	1.311e-54	194.0	COG2703@1|root,COG2703@2|Bacteria,1RD1Z@1224|Proteobacteria	1224|Proteobacteria	P	Pfam Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_5649797_13	269799.Gmet_2435	2.273e-82	278.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,42SC9@68525|delta/epsilon subdivisions,2WPDZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
REGS1_k127_5649797_1	398767.Glov_3229	0.0	1123.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,42NGX@68525|delta/epsilon subdivisions,2WJC0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434	E1-E2_ATPase,Hydrolase
REGS1_k127_5649797_3	243231.GSU2480	9.479e-303	936.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,42NCD@68525|delta/epsilon subdivisions,2WJ03@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
REGS1_k127_5649797_16	316067.Geob_1999	8.376e-18	83.0	2EIC1@1|root,33C3D@2|Bacteria,1NHMH@1224|Proteobacteria,42WXS@68525|delta/epsilon subdivisions,2WT9H@28221|Deltaproteobacteria,43VPD@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
REGS1_k127_5649797_7	1121918.ARWE01000001_gene3573	1.637e-123	403.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_5649797_12	1121918.ARWE01000001_gene3572	2.047e-95	334.0	COG5000@1|root,COG5000@2|Bacteria,1NU7E@1224|Proteobacteria,43DDR@68525|delta/epsilon subdivisions,2X8JR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Response_reg
REGS1_k127_5649797_18	1353276.JADR01000006_gene1072	1.881e-08	67.0	COG2203@1|root,COG5000@1|root,COG2203@2|Bacteria,COG5000@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Cache_3-Cache_2,GAF,GAF_2,GGDEF,GerE,HAMP,HATPase_c,MCPsignal,PAS,PAS_4,PAS_8,PAS_9,dCache_1
REGS1_k127_5649797_14	1348657.M622_02075	3.482e-59	221.0	COG2199@1|root,COG3706@2|Bacteria,1QUXS@1224|Proteobacteria,2VSNE@28216|Betaproteobacteria,2KYT6@206389|Rhodocyclales	206389|Rhodocyclales	T	COG2202 FOG PAS PAC domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,MASE3,PAS_3,PAS_4
REGS1_k127_5675113_4	316067.Geob_2834	2.98e-24	108.0	COG0715@1|root,COG0715@2|Bacteria,1NUUC@1224|Proteobacteria,43252@68525|delta/epsilon subdivisions,2WXTQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
REGS1_k127_5675113_1	192952.MM_0172	1.728e-137	448.0	COG2203@1|root,arCOG02352@1|root,arCOG02352@2157|Archaea,arCOG02361@2157|Archaea	2157|Archaea	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HATPase_c,HisKA_2,PAS,PAS_3,PAS_4,PAS_9,PocR,Response_reg
REGS1_k127_5675113_0	269799.Gmet_0789	2.353e-260	812.0	COG1012@1|root,COG1012@2|Bacteria,1R3TA@1224|Proteobacteria,42PG8@68525|delta/epsilon subdivisions,2WKCP@28221|Deltaproteobacteria,43SY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_5675113_3	331113.SNE_A09700	2.449e-43	160.0	COG2154@1|root,COG2154@2|Bacteria,2JGH7@204428|Chlamydiae	204428|Chlamydiae	H	Pterin 4 alpha carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
REGS1_k127_5675113_2	269799.Gmet_3377	2.091e-61	216.0	COG1397@1|root,COG1397@2|Bacteria,1RA82@1224|Proteobacteria,42QPD@68525|delta/epsilon subdivisions,2WMNN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
REGS1_k127_5813091_4	243231.GSU3306	9.598e-06	49.0	COG5386@1|root,COG5386@2|Bacteria,1QWPV@1224|Proteobacteria,43BUN@68525|delta/epsilon subdivisions,2X75R@28221|Deltaproteobacteria,43UJG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
REGS1_k127_5813091_1	1232410.KI421413_gene475	2.148e-109	360.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,42MVW@68525|delta/epsilon subdivisions,2WNRN@28221|Deltaproteobacteria,43U95@69541|Desulfuromonadales	28221|Deltaproteobacteria	CH	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
REGS1_k127_5813091_0	1232410.KI421413_gene476	5e-324	1003.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,42SPZ@68525|delta/epsilon subdivisions,2WIV9@28221|Deltaproteobacteria,43VZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
REGS1_k127_5813091_2	1232410.KI421413_gene477	1.323e-105	354.0	COG1139@1|root,COG1139@2|Bacteria,1NS3B@1224|Proteobacteria,42Y64@68525|delta/epsilon subdivisions,2WTW2@28221|Deltaproteobacteria,43TRA@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
REGS1_k127_5813091_3	243231.GSU2726	1.287e-19	91.0	2EUXR@1|root,33ND1@2|Bacteria,1P0HH@1224|Proteobacteria,431FA@68525|delta/epsilon subdivisions,2WWMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_581726_3	269799.Gmet_2404	8.815e-42	156.0	COG3605@1|root,COG3605@2|Bacteria,1QTTV@1224|Proteobacteria,42PST@68525|delta/epsilon subdivisions,2WJ3A@28221|Deltaproteobacteria,43UG1@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	TIGRFAM phosphoenolpyruvate-protein phosphotransferase	ptsP	-	2.7.3.9	ko:K08484	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	GAF_2,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
REGS1_k127_581726_0	398767.Glov_2573	0.0	1249.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_581726_4	338966.Ppro_3509	2.181e-24	105.0	2DYE1@1|root,349AP@2|Bacteria,1NZTB@1224|Proteobacteria,4319C@68525|delta/epsilon subdivisions,2WWY1@28221|Deltaproteobacteria,43VDM@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Class III cytochrome C family	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII
REGS1_k127_581726_1	443144.GM21_0493	1.306e-93	321.0	COG2199@1|root,COG2204@1|root,COG2199@2|Bacteria,COG2204@2|Bacteria,1QVAY@1224|Proteobacteria,42TG1@68525|delta/epsilon subdivisions,2WVCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response receiver sensor diguanylate cyclase, PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_4,Response_reg
REGS1_k127_581726_6	1278307.KB906986_gene4291	0.0001894	49.0	291D4@1|root,2ZNZZ@2|Bacteria,1P4BS@1224|Proteobacteria,1SUWX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_581726_2	290397.Adeh_3062	9.719e-74	258.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_5848323_8	903818.KI912268_gene1123	3.113e-08	55.0	COG1894@1|root,COG1894@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.12.1.3,1.6.5.3	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
REGS1_k127_5848323_0	1499967.BAYZ01000171_gene5567	2.123e-311	990.0	COG1148@1|root,COG4231@1|root,COG1148@2|Bacteria,COG4231@2|Bacteria	2|Bacteria	C	indolepyruvate ferredoxin oxidoreductase activity	bamE	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_oxidored,Fer4,Fer4_20,Fer4_7,Pyr_redox_2
REGS1_k127_5848323_6	706587.Desti_5587	2.846e-56	200.0	COG1908@1|root,COG1908@2|Bacteria,1RGF7@1224|Proteobacteria,42S3H@68525|delta/epsilon subdivisions,2WNTN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
REGS1_k127_5848323_4	644282.Deba_2152	2.099e-75	259.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
REGS1_k127_5848323_3	2880.D7G0G7	6.419e-90	307.0	COG2055@1|root,2QRW5@2759|Eukaryota	2759|Eukaryota	C	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
REGS1_k127_5848323_5	243231.GSU0384	1.083e-62	218.0	COG1633@1|root,COG1633@2|Bacteria,1NVAF@1224|Proteobacteria,42ZHS@68525|delta/epsilon subdivisions,2WV0C@28221|Deltaproteobacteria,43UQE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_5848323_1	1121918.ARWE01000001_gene955	1.312e-290	897.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MB6@68525|delta/epsilon subdivisions,2WJMI@28221|Deltaproteobacteria,43SU1@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Acetyl-CoA hydrolase/transferase N-terminal domain	ato-1	-	2.8.3.18,3.1.2.1	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00227,R10343	RC00004,RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1125	AcetylCoA_hyd_C,AcetylCoA_hydro
REGS1_k127_5848323_2	316067.Geob_0407	8.784e-189	600.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,43UDA@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM peptidase S1 and S6, chymotrypsin Hap	degP	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_5909334_0	404380.Gbem_1227	4.84e-191	614.0	COG0642@1|root,COG2770@1|root,COG5002@1|root,COG0642@2|Bacteria,COG2770@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	4HB_MCP_1,HAMP,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,SBP_bac_3,dCache_1
REGS1_k127_5909334_1	443143.GM18_1090	4.5e-47	175.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2WIYG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_5932103_5	243231.GSU3460	4.432e-44	162.0	COG1215@1|root,COG2344@1|root,COG1215@2|Bacteria,COG2344@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,43S6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_5932103_2	316067.Geob_0560	5.584e-90	301.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,42RJ4@68525|delta/epsilon subdivisions,2WNQ3@28221|Deltaproteobacteria,43SZQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
REGS1_k127_5932103_3	404380.Gbem_3798	6.116e-78	263.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,42MJ6@68525|delta/epsilon subdivisions,2WJ67@28221|Deltaproteobacteria,43UN0@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
REGS1_k127_5932103_1	316067.Geob_0557	2.445e-163	533.0	COG1352@1|root,COG1352@2|Bacteria,1R6N1@1224|Proteobacteria,42T12@68525|delta/epsilon subdivisions,2WPTY@28221|Deltaproteobacteria,43TRF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg,TPR_16
REGS1_k127_5932103_4	316067.Geob_0556	4.308e-53	192.0	COG0835@1|root,COG0835@2|Bacteria,1NXFR@1224|Proteobacteria,430RD@68525|delta/epsilon subdivisions,2WVV0@28221|Deltaproteobacteria,43V76@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	cheW40H-3	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_5932103_0	316067.Geob_0555	1.099e-202	639.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria,43T5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	mcp40H-17	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,MCPsignal
REGS1_k127_5983733_4	886293.Sinac_2020	7.063e-167	528.0	COG0364@1|root,COG0364@2|Bacteria,2IYER@203682|Planctomycetes	203682|Planctomycetes	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
REGS1_k127_5983733_6	269799.Gmet_2618	3.122e-94	315.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,43TFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
REGS1_k127_5983733_8	391165.GbCGDNIH1_0537	1.466e-78	269.0	COG1940@1|root,COG1940@2|Bacteria,1NSQA@1224|Proteobacteria,2TSPZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GK	Transcriptional regulator sugar kinase	-	-	2.7.1.63	ko:K00886	ko00010,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R02187,R02189	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
REGS1_k127_5983733_1	1121918.ARWE01000001_gene3110	0.0	1238.0	COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,42YST@68525|delta/epsilon subdivisions,2WURK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Glucodextranase, domain N	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	Glucodextran_N,Glyco_hydro_15
REGS1_k127_5983733_10	243231.GSU1278	3.666e-27	114.0	COG2846@1|root,COG2846@2|Bacteria	2|Bacteria	D	Di-iron-containing protein involved in the repair of iron-sulfur clusters	-	-	-	ko:K07322	-	-	-	-	ko00000	-	-	-	DUF1858,Hemerythrin
REGS1_k127_5983733_7	398767.Glov_2078	2.517e-84	281.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,43SYB@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_5983733_0	316067.Geob_3271	0.0	1890.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria,43TR2@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
REGS1_k127_5983733_9	398767.Glov_2080	1.686e-60	210.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,42SES@68525|delta/epsilon subdivisions,2WQ9T@28221|Deltaproteobacteria,43SNM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
REGS1_k127_5983733_5	398767.Glov_2082	2.069e-154	492.0	COG1313@1|root,COG1313@2|Bacteria,1NZAK@1224|Proteobacteria,42NYF@68525|delta/epsilon subdivisions,2WIT2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_5983733_2	398767.Glov_2083	3.368e-229	711.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,42KZG@68525|delta/epsilon subdivisions,2WIQ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarA family	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
REGS1_k127_5983733_3	398767.Glov_2084	5.969e-227	709.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,43TM6@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
REGS1_k127_5983733_11	398767.Glov_2085	7.661e-22	94.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,43TAD@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_5991307_18	1265502.KB905929_gene2189	6.1e-39	148.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VQJ3@28216|Betaproteobacteria,4AF5F@80864|Comamonadaceae	28216|Betaproteobacteria	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
REGS1_k127_5991307_9	1121918.ARWE01000001_gene2	4.664e-74	253.0	COG1335@1|root,COG1335@2|Bacteria,1RDHA@1224|Proteobacteria,42S3C@68525|delta/epsilon subdivisions,2WNV0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM isochorismatase hydrolase	yddQ	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
REGS1_k127_5991307_8	338963.Pcar_2797	3.127e-75	256.0	COG1592@1|root,COG1592@2|Bacteria,1R9WG@1224|Proteobacteria,42N9V@68525|delta/epsilon subdivisions,2WV40@28221|Deltaproteobacteria,43USY@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Ferritin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_5991307_14	1232437.KL662040_gene2116	3.287e-50	185.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria,42PKS@68525|delta/epsilon subdivisions,2WKCD@28221|Deltaproteobacteria,2MPM3@213118|Desulfobacterales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,PocR,sCache_2
REGS1_k127_5991307_1	1121918.ARWE01000001_gene2537	1.186e-151	500.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8
REGS1_k127_5991307_5	404380.Gbem_1110	2.771e-105	346.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,42P7H@68525|delta/epsilon subdivisions,2WKJA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,GtrA
REGS1_k127_5991307_0	404380.Gbem_2077	0.0	1536.0	COG2710@1|root,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,42M5T@68525|delta/epsilon subdivisions,2WJF2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NifD NifK NifE NifN family	nifEN	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
REGS1_k127_5991307_15	243231.GSU2319	1.805e-49	182.0	COG4446@1|root,COG4446@2|Bacteria,1N7IZ@1224|Proteobacteria,42V21@68525|delta/epsilon subdivisions,2WRFF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1499)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1499
REGS1_k127_5991307_10	269799.Gmet_1203	2.61e-72	246.0	COG4420@1|root,COG4420@2|Bacteria,1RIDY@1224|Proteobacteria,42WI7@68525|delta/epsilon subdivisions,2WSAF@28221|Deltaproteobacteria,43VM2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1003
REGS1_k127_5991307_6	443143.GM18_0451	3.722e-91	305.0	COG1102@1|root,COG1102@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
REGS1_k127_5991307_12	316067.Geob_2582	2.565e-55	196.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,42W01@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Dinitrogenase iron-molybdenum cofactor biosynthesis protein	nifX	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
REGS1_k127_5991307_16	269799.Gmet_0672	9.011e-48	173.0	COG1149@1|root,COG1149@2|Bacteria,1QXPC@1224|Proteobacteria,42XYH@68525|delta/epsilon subdivisions,2WW0H@28221|Deltaproteobacteria,43V4X@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	fdxN	-	-	-	-	-	-	-	-	-	-	-	Fer4_21,Fer4_7,Fer4_9
REGS1_k127_5991307_17	269799.Gmet_0673	1.983e-41	155.0	COG1433@1|root,COG1433@2|Bacteria,1RJWN@1224|Proteobacteria,42X1I@68525|delta/epsilon subdivisions,2WSQ9@28221|Deltaproteobacteria,43VC4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	nifB	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0673	Nitro_FeMo-Co
REGS1_k127_5991307_3	316067.Geob_2585	9.144e-133	426.0	28IJT@1|root,2Z8KN@2|Bacteria,1R6VB@1224|Proteobacteria,42NZB@68525|delta/epsilon subdivisions,2WJ40@28221|Deltaproteobacteria,43U8Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM Dinitrogenase reductase ADP-ribosyltransferase	draT	-	2.4.2.37	ko:K05951	-	-	-	-	ko00000,ko01000	-	-	-	DRAT
REGS1_k127_5991307_20	1123487.KB892846_gene432	2.005e-25	109.0	2DTEC@1|root,33JZH@2|Bacteria,1NMI2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5991307_19	1123256.KB907934_gene2403	1.202e-28	117.0	2AQ99@1|root,31FF5@2|Bacteria,1QCYT@1224|Proteobacteria,1T8SX@1236|Gammaproteobacteria,1XB6T@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5991307_7	316067.Geob_3143	1.226e-78	265.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,42SFW@68525|delta/epsilon subdivisions,2WPH3@28221|Deltaproteobacteria,43UT5@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	cobA	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
REGS1_k127_5991307_11	316067.Geob_3142	4.089e-70	238.0	COG2185@1|root,COG2185@2|Bacteria,1RKGS@1224|Proteobacteria,42SKV@68525|delta/epsilon subdivisions,2WP2X@28221|Deltaproteobacteria,43UUC@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	B12 binding domain	-	-	5.4.99.2	ko:K01849	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
REGS1_k127_5991307_2	316067.Geob_3140	5.088e-138	445.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,42NBN@68525|delta/epsilon subdivisions,2WK8A@28221|Deltaproteobacteria,43U0B@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	TIGRFAM LAO AO transport system ATPase	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
REGS1_k127_5991307_4	443144.GM21_1550	4.348e-129	417.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,PG_binding_4,YkuD
REGS1_k127_5991307_13	404380.Gbem_1327	7.798e-54	195.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria	1224|Proteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
REGS1_k127_6032212_1	269799.Gmet_2877	1.403e-298	930.0	COG5617@1|root,COG5617@2|Bacteria,1QXN8@1224|Proteobacteria,431TV@68525|delta/epsilon subdivisions,2WWBH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6032212_6	316067.Geob_1674	1.964e-89	302.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,43TT9@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
REGS1_k127_6032212_2	269799.Gmet_0902	1.01e-253	789.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria,43U7M@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0902	Sacchrp_dh_C,Sacchrp_dh_NADP
REGS1_k127_6032212_3	269799.Gmet_0903	2.297e-229	713.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2WITG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,Orn_DAP_Arg_deC
REGS1_k127_6032212_0	316067.Geob_1678	0.0	1206.0	COG1166@1|root,COG1166@2|Bacteria,1MU80@1224|Proteobacteria,42M2B@68525|delta/epsilon subdivisions,2WJDZ@28221|Deltaproteobacteria,43U1K@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
REGS1_k127_6032212_8	316067.Geob_1222	4.783e-28	130.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_6032212_7	243231.GSU3088	3.893e-75	255.0	COG2606@1|root,COG2606@2|Bacteria,1RGX5@1224|Proteobacteria,42RNH@68525|delta/epsilon subdivisions,2X5NY@28221|Deltaproteobacteria,43UM6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
REGS1_k127_6032212_5	316067.Geob_1717	1.531e-123	402.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42MFD@68525|delta/epsilon subdivisions,2WM9M@28221|Deltaproteobacteria,43S95@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sir2 family	srtN	-	-	-	-	-	-	-	-	-	-	-	SIR2
REGS1_k127_6032212_4	1232410.KI421413_gene867	3.182e-165	522.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria,43UID@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Nucleotidyl transferase	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
REGS1_k127_6133307_13	877455.Metbo_0947	4.165e-26	129.0	COG4934@1|root,arCOG03665@2157|Archaea	2157|Archaea	O	tripeptidyl-peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,Pro-kuma_activ
REGS1_k127_6133307_9	1321784.HMPREF1987_02363	1.604e-55	226.0	COG3391@1|root,COG3391@2|Bacteria,1VCN6@1239|Firmicutes,25BR7@186801|Clostridia	186801|Clostridia	S	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_6133307_8	243231.GSU3016	8.695e-63	250.0	COG0823@1|root,COG2885@1|root,COG3291@1|root,COG4412@1|root,COG5492@1|root,COG0823@2|Bacteria,COG2885@2|Bacteria,COG3291@2|Bacteria,COG4412@2|Bacteria,COG5492@2|Bacteria,1PMFY@1224|Proteobacteria,42Y8D@68525|delta/epsilon subdivisions,2WUNZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Chitobiase/beta-hexosaminidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1
REGS1_k127_6133307_6	483219.LILAB_18585	1.2e-111	412.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	2|Bacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Big_2,CHU_C,RCC1
REGS1_k127_6133307_15	536227.CcarbDRAFT_0082	1.554e-22	117.0	COG1361@1|root,COG3209@1|root,COG3637@1|root,COG4886@1|root,COG5492@1|root,COG1361@2|Bacteria,COG3209@2|Bacteria,COG3637@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	oprH	-	-	ko:K02014,ko:K12287,ko:K16087	-	-	-	-	ko00000,ko02000,ko02044	1.B.14,1.B.14.2	-	-	Big_2,DUF11,OMP_b-brl,fn3
REGS1_k127_6133307_3	521011.Mpal_0423	3.627e-175	622.0	COG3391@1|root,arCOG02516@1|root,arCOG02516@2157|Archaea,arCOG03563@2157|Archaea,2Y7Y4@28890|Euryarchaeota,2NBN4@224756|Methanomicrobia	2157|Archaea	S	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,Kelch_4,NHL,PKD
REGS1_k127_6133307_14	1499967.BAYZ01000068_gene1935	1.934e-24	123.0	COG3266@1|root,COG3420@1|root,COG4733@1|root,COG3266@2|Bacteria,COG3420@2|Bacteria,COG4733@2|Bacteria,2NS5M@2323|unclassified Bacteria	2|Bacteria	P	Fibronectin type 3 domain	-	-	-	ko:K12685,ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko02044	1.B.12.5.1,1.B.12.5.3,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CHB_HEX_C_1,CHU_C,DUF1573,DUF285,F5_F8_type_C,Laminin_G_3,Lectin_legB,fn3
REGS1_k127_6133307_11	1122939.ATUD01000001_gene577	1.237e-40	177.0	COG1520@1|root,COG1520@2|Bacteria,2H3K4@201174|Actinobacteria,4CRJK@84995|Rubrobacteria	84995|Rubrobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6133307_1	1123242.JH636435_gene2223	1.039e-200	651.0	COG1520@1|root,COG3391@1|root,COG1520@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114
REGS1_k127_6133307_0	443143.GM18_3665	3.56e-241	754.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,43TJ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_6133307_2	316067.Geob_2080	8.345e-187	596.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WNZ3@28221|Deltaproteobacteria,43SW2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM peptidase M16 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_6133307_7	316067.Geob_1721	8.089e-84	281.0	COG1335@1|root,COG1335@2|Bacteria,1MU5N@1224|Proteobacteria,42RN4@68525|delta/epsilon subdivisions,2WP37@28221|Deltaproteobacteria,43SJR@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
REGS1_k127_6133307_12	1304885.AUEY01000036_gene2273	1.001e-26	114.0	COG2204@1|root,COG2204@2|Bacteria,1QW8K@1224|Proteobacteria,42V8F@68525|delta/epsilon subdivisions,2WRMW@28221|Deltaproteobacteria,2MNUV@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_6133307_4	443144.GM21_2079	5.491e-134	450.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,dCache_1
REGS1_k127_6133307_5	1304885.AUEY01000021_gene3474	3.824e-122	419.0	COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,1NWNJ@1224|Proteobacteria,43DBR@68525|delta/epsilon subdivisions,2X8HR@28221|Deltaproteobacteria,2MPNM@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9
REGS1_k127_6133307_10	1173028.ANKO01000017_gene263	1.503e-54	209.0	COG0642@1|root,COG2203@1|root,COG2905@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG2905@2|Bacteria,1G09B@1117|Cyanobacteria,1H71H@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_6134685_19	269799.Gmet_0588	1.243e-164	538.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,42MT2@68525|delta/epsilon subdivisions,2WKWA@28221|Deltaproteobacteria,43TXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Tetratricopeptide TPR_1 repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
REGS1_k127_6134685_55	1201288.M900_0492	5.605e-93	317.0	COG0535@1|root,COG0535@2|Bacteria,1NVXA@1224|Proteobacteria,42NYH@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
REGS1_k127_6134685_107	106648.BBLJ01000001_gene2293	1.418e-13	81.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,3NJ1D@468|Moraxellaceae	1236|Gammaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
REGS1_k127_6134685_88	1537917.JU82_09620	3.063e-37	155.0	COG0535@1|root,COG0535@2|Bacteria,1PHAQ@1224|Proteobacteria,42Q23@68525|delta/epsilon subdivisions,2YNTM@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,SPASM
REGS1_k127_6134685_44	156889.Mmc1_0710	9.144e-109	371.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TUPK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_6134685_103	290397.Adeh_4291	5.815e-19	97.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,42MGE@68525|delta/epsilon subdivisions,2WJC2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
REGS1_k127_6134685_18	316067.Geob_0664	1.127e-167	533.0	COG0535@1|root,COG0535@2|Bacteria,1R4I0@1224|Proteobacteria,42MFB@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
REGS1_k127_6134685_43	316067.Geob_0665	5.106e-109	358.0	COG0500@1|root,COG2226@2|Bacteria,1QSZ6@1224|Proteobacteria,42R0V@68525|delta/epsilon subdivisions,2WU7Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
REGS1_k127_6134685_45	316067.Geob_0666	1.039e-108	359.0	COG3958@1|root,COG3958@2|Bacteria,1MWIX@1224|Proteobacteria,42PG6@68525|delta/epsilon subdivisions,2X618@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
REGS1_k127_6134685_77	234267.Acid_3622	1.391e-53	208.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_6134685_39	316067.Geob_0667	1.277e-116	380.0	COG3959@1|root,COG3959@2|Bacteria,1MWRX@1224|Proteobacteria,42P7U@68525|delta/epsilon subdivisions,2WKZQ@28221|Deltaproteobacteria,43RXC@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM Transketolase domain protein	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
REGS1_k127_6134685_109	208444.JNYY01000001_gene5186	1.028e-11	74.0	COG1216@1|root,COG1216@2|Bacteria,2I2FA@201174|Actinobacteria,4DYYD@85010|Pseudonocardiales	201174|Actinobacteria	S	Glycosyltransferase like family 2	dpm1	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
REGS1_k127_6134685_68	316067.Geob_0670	4.681e-71	252.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
REGS1_k127_6134685_57	509191.AEDB02000049_gene4364	2.26e-89	306.0	COG0535@1|root,COG0535@2|Bacteria,1UY09@1239|Firmicutes,24D8R@186801|Clostridia,3WQPW@541000|Ruminococcaceae	186801|Clostridia	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
REGS1_k127_6134685_94	1400524.KL370779_gene630	1.559e-33	137.0	COG1071@1|root,COG1071@2|Bacteria	2|Bacteria	C	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	pdhA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K11381	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
REGS1_k127_6134685_98	331113.SNE_A22850	7.509e-23	104.0	COG0022@1|root,COG0022@2|Bacteria,2JFIU@204428|Chlamydiae	2|Bacteria	C	Pyruvate dehydrogenase E1	acoB	-	1.2.4.1	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
REGS1_k127_6134685_28	1280664.AUIX01000015_gene2196	6.47e-135	440.0	COG0535@1|root,COG0535@2|Bacteria,1UET7@1239|Firmicutes,24F49@186801|Clostridia,4C0TW@830|Butyrivibrio	186801|Clostridia	S	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
REGS1_k127_6134685_59	398767.Glov_3383	5.92e-88	304.0	COG0859@1|root,COG0859@2|Bacteria,1NCZT@1224|Proteobacteria,42QXE@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
REGS1_k127_6134685_54	395494.Galf_1097	6.258e-94	334.0	COG1032@1|root,COG1032@2|Bacteria,1Q5NG@1224|Proteobacteria,2WB3N@28216|Betaproteobacteria,44WNP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_6134685_36	269799.Gmet_0584	7.188e-124	416.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
REGS1_k127_6134685_26	595460.RRSWK_03709	6.72e-139	464.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,2IYMF@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
REGS1_k127_6134685_70	1216976.AX27061_3674	1.061e-62	241.0	COG0421@1|root,COG0421@2|Bacteria,1QY0T@1224|Proteobacteria,2WH8S@28216|Betaproteobacteria,3T9JQ@506|Alcaligenaceae	28216|Betaproteobacteria	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_6134685_32	269799.Gmet_0584	2.42e-130	436.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
REGS1_k127_6134685_64	765913.ThidrDRAFT_3902	1.685e-79	279.0	COG3475@1|root,COG3475@2|Bacteria,1NI2D@1224|Proteobacteria,1TKC2@1236|Gammaproteobacteria,1X1RH@135613|Chromatiales	135613|Chromatiales	M	LICD family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_96	926561.KB900617_gene2081	1.576e-32	136.0	COG0778@1|root,COG0778@2|Bacteria,1V75Q@1239|Firmicutes,24J37@186801|Clostridia	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_6134685_25	1121456.ATVA01000015_gene2482	2.88e-139	464.0	COG0451@1|root,COG0451@2|Bacteria,1NEDD@1224|Proteobacteria,42QH7@68525|delta/epsilon subdivisions,2WIME@28221|Deltaproteobacteria,2MDGB@213115|Desulfovibrionales	28221|Deltaproteobacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_35	269799.Gmet_0584	7.92e-127	424.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
REGS1_k127_6134685_112	1122176.KB903546_gene998	1.687e-07	59.0	COG2246@1|root,COG2246@2|Bacteria,4P8PV@976|Bacteroidetes,1IZZT@117747|Sphingobacteriia	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
REGS1_k127_6134685_56	309799.DICTH_0560	1.375e-91	312.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	arnC	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
REGS1_k127_6134685_48	909663.KI867150_gene213	9.397e-102	359.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
REGS1_k127_6134685_69	316067.Geob_1171	3.022e-64	227.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42QU4@68525|delta/epsilon subdivisions,2WMRQ@28221|Deltaproteobacteria,43SHI@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
REGS1_k127_6134685_14	1244869.H261_20969	4.625e-173	557.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,2TUPK@28211|Alphaproteobacteria,2JPEX@204441|Rhodospirillales	204441|Rhodospirillales	C	magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase	bchE	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
REGS1_k127_6134685_86	696369.KI912183_gene1207	1.341e-38	154.0	COG0500@1|root,COG0500@2|Bacteria,1VJS9@1239|Firmicutes,24TBM@186801|Clostridia	186801|Clostridia	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_6134685_66	1047013.AQSP01000144_gene899	1.786e-74	259.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2,GtrA
REGS1_k127_6134685_110	931276.Cspa_c43410	9.084e-11	73.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,24HII@186801|Clostridia,36FRR@31979|Clostridiaceae	186801|Clostridia	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
REGS1_k127_6134685_13	1232410.KI421412_gene257	5.35e-174	554.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,43T07@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_6134685_52	28444.JODQ01000008_gene1053	5.512e-97	342.0	COG0421@1|root,COG0421@2|Bacteria,2I3HX@201174|Actinobacteria,4EHKS@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
REGS1_k127_6134685_79	43989.cce_1407	9.032e-51	183.0	2BWTW@1|root,315N7@2|Bacteria,1G5TV@1117|Cyanobacteria,3KHRT@43988|Cyanothece	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_30	269799.Gmet_0584	8.739e-133	442.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
REGS1_k127_6134685_38	269799.Gmet_0584	4.028e-122	421.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
REGS1_k127_6134685_75	344747.PM8797T_23856	1.257e-54	212.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_6134685_101	1123393.KB891333_gene2602	3.998e-22	108.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria	28216|Betaproteobacteria	O	TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,MethyTransf_Reg,SEC-C,TPR_1,TPR_16,TPR_19,TPR_2,TPR_8
REGS1_k127_6134685_53	909663.KI867150_gene214	6.868e-97	329.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
REGS1_k127_6134685_111	497964.CfE428DRAFT_4966	1.18e-09	71.0	COG0457@1|root,COG0457@2|Bacteria	497964.CfE428DRAFT_4966|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_81	589865.DaAHT2_2410	4.745e-48	186.0	COG0535@1|root,COG0535@2|Bacteria,1RADC@1224|Proteobacteria,42RDA@68525|delta/epsilon subdivisions,2WN4I@28221|Deltaproteobacteria,2MM5N@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM,SPASM
REGS1_k127_6134685_89	1229172.JQFA01000002_gene4993	8.556e-35	147.0	COG1216@1|root,COG1216@2|Bacteria,1G0PG@1117|Cyanobacteria,1H8A8@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_6134685_50	909663.KI867150_gene213	2.949e-98	349.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
REGS1_k127_6134685_108	761193.Runsl_3791	5.784e-13	74.0	2CH0Y@1|root,32S8V@2|Bacteria,4NSPM@976|Bacteroidetes,47RDF@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_72	1122132.AQYH01000010_gene4009	1.471e-57	212.0	COG2755@1|root,COG2755@2|Bacteria,1NHW6@1224|Proteobacteria	1224|Proteobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
REGS1_k127_6134685_115	1045855.DSC_00190	1.286e-05	48.0	COG3335@1|root,COG3335@2|Bacteria,1MW7X@1224|Proteobacteria,1S900@1236|Gammaproteobacteria,1XBP9@135614|Xanthomonadales	135614|Xanthomonadales	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
REGS1_k127_6134685_105	156889.Mmc1_0763	1.303e-15	77.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria,2UJXH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_2	880071.Fleli_3930	5.627e-272	849.0	COG2192@1|root,COG2192@2|Bacteria,4NEV9@976|Bacteroidetes,47JR5@768503|Cytophagia	976|Bacteroidetes	O	PFAM Carbamoyltransferase	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
REGS1_k127_6134685_15	312153.Pnuc_0335	8.381e-171	549.0	COG0500@1|root,COG1215@1|root,COG1215@2|Bacteria,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
REGS1_k127_6134685_65	439235.Dalk_2158	2.188e-78	280.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42TFM@68525|delta/epsilon subdivisions,2WPBE@28221|Deltaproteobacteria,2MK7R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_6134685_84	43989.cce_0521	1.887e-40	160.0	COG2520@1|root,COG2520@2|Bacteria,1GA8M@1117|Cyanobacteria	1117|Cyanobacteria	J	Methyltransferase FkbM domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
REGS1_k127_6134685_76	1210884.HG799467_gene13174	1.579e-54	211.0	COG1807@1|root,COG1807@2|Bacteria,2IZFZ@203682|Planctomycetes	203682|Planctomycetes	M	Tetratricopeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_6134685_17	243231.GSU2898	3.59e-169	593.0	COG0484@1|root,COG3880@1|root,COG0484@2|Bacteria,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_6134685_87	404380.Gbem_1155	1.738e-37	167.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	Cadherin,CarboxypepD_reg,DUF11,SdrD_B
REGS1_k127_6134685_3	243231.GSU2898	1.289e-255	887.0	COG0484@1|root,COG3880@1|root,COG0484@2|Bacteria,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_6134685_4	269799.Gmet_0695	2.473e-248	773.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,43U57@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TIGRFAM ammonium transporter	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
REGS1_k127_6134685_73	243231.GSU0939	1.97e-56	198.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,43V1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Nitrogen regulatory protein P-II	glnK	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
REGS1_k127_6134685_49	269799.Gmet_0693	2.428e-99	331.0	2EFEP@1|root,3397H@2|Bacteria,1NIUR@1224|Proteobacteria,42XV7@68525|delta/epsilon subdivisions,2WSZK@28221|Deltaproteobacteria,43UNZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_80	243231.GSU2822	3.118e-48	179.0	COG3707@1|root,COG3707@2|Bacteria,1QT1E@1224|Proteobacteria,42UUT@68525|delta/epsilon subdivisions,2WQIX@28221|Deltaproteobacteria,43UTH@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nitrogen fixation transcript antitermination response regulator, ANTAR domain-containing	gnfR	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
REGS1_k127_6134685_92	269799.Gmet_0340	1.773e-34	132.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_6134685_27	338966.Ppro_2030	2.094e-137	457.0	COG1846@1|root,COG1846@2|Bacteria,1NRG9@1224|Proteobacteria,42YC6@68525|delta/epsilon subdivisions,2WTKJ@28221|Deltaproteobacteria,43TP5@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
REGS1_k127_6134685_10	338966.Ppro_2031	8.134e-187	589.0	COG2805@1|root,COG2805@2|Bacteria,1R6FY@1224|Proteobacteria,42MPJ@68525|delta/epsilon subdivisions,2WK57@28221|Deltaproteobacteria,43SCV@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type II/IV secretion system protein	pilT-2	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_6134685_47	398767.Glov_3211	2.125e-102	342.0	2A8H0@1|root,30XJ2@2|Bacteria,1REE0@1224|Proteobacteria,42SSU@68525|delta/epsilon subdivisions,2WUYB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_46	243231.GSU1220	2.193e-107	354.0	COG0745@1|root,COG0745@2|Bacteria,1QXNP@1224|Proteobacteria,43062@68525|delta/epsilon subdivisions,2WVCI@28221|Deltaproteobacteria,43V25@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE_N
REGS1_k127_6134685_99	316067.Geob_0181	1.112e-22	108.0	COG3291@1|root,COG3291@2|Bacteria,1R5MU@1224|Proteobacteria,42UIQ@68525|delta/epsilon subdivisions,2WQAN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Repeats in polycystic kidney disease 1 (PKD1) and other proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_62	316067.Geob_1803	7.436e-82	281.0	COG0810@1|root,COG0810@2|Bacteria	2|Bacteria	M	energy transducer activity	tonB3	-	-	ko:K03646,ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1,2.C.1.2	-	-	TonB_2,TonB_C
REGS1_k127_6134685_34	316067.Geob_1776	3.537e-128	416.0	COG0861@1|root,COG0861@2|Bacteria,1MUNR@1224|Proteobacteria,42PJP@68525|delta/epsilon subdivisions,2WJI0@28221|Deltaproteobacteria,43TJP@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
REGS1_k127_6134685_12	316067.Geob_1775	7.247e-179	569.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42N97@68525|delta/epsilon subdivisions,2WKVE@28221|Deltaproteobacteria,43S28@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	CBS domain containing protein	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
REGS1_k127_6134685_20	316067.Geob_1986	6.888e-155	502.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA-1	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
REGS1_k127_6134685_41	316067.Geob_2237	3.513e-113	374.0	COG3267@1|root,COG3267@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	SMART AAA ATPase	-	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
REGS1_k127_6134685_83	269799.Gmet_0876	5.964e-42	163.0	2A7N3@1|root,30WK3@2|Bacteria,1NERD@1224|Proteobacteria,42P7M@68525|delta/epsilon subdivisions,2WJTH@28221|Deltaproteobacteria,43S5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_91	269799.Gmet_0877	1.276e-34	134.0	COG2983@1|root,COG2983@2|Bacteria,1RHMX@1224|Proteobacteria,42VQD@68525|delta/epsilon subdivisions,2WSB7@28221|Deltaproteobacteria,43VF9@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the UPF0260 family	-	-	-	ko:K09160	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_6134685_21	243231.GSU2568	5.892e-152	491.0	COG0621@1|root,COG0621@2|Bacteria,1MUCS@1224|Proteobacteria,42MN1@68525|delta/epsilon subdivisions,2WJ1H@28221|Deltaproteobacteria,43TX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	SMART Elongator protein 3 MiaB NifB	mtaB	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
REGS1_k127_6134685_40	443143.GM18_3303	7.75e-115	381.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
REGS1_k127_6134685_42	443143.GM18_1475	1.332e-111	363.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,43TDK@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Serine acetyltransferase, N-terminal	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
REGS1_k127_6134685_24	269799.Gmet_2395	3.479e-144	459.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WK9D@28221|Deltaproteobacteria,43S0Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	frdB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2395	Fer2_3,Fer4_7,Fer4_8
REGS1_k127_6134685_0	398767.Glov_2213	0.0	1167.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WIJ5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	frdA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_6134685_61	316067.Geob_1882	5.539e-82	279.0	2CAZH@1|root,2Z7RU@2|Bacteria,1RBDC@1224|Proteobacteria,42SC7@68525|delta/epsilon subdivisions,2WP8S@28221|Deltaproteobacteria,43SJW@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	frdC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
REGS1_k127_6134685_8	316067.Geob_1881	1.425e-215	672.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43SUZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt-1	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
REGS1_k127_6134685_58	1242864.D187_001377	2.987e-88	310.0	COG3829@1|root,COG4251@1|root,COG3829@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42QPS@68525|delta/epsilon subdivisions,2WMWT@28221|Deltaproteobacteria,2YZD5@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9,dCache_1
REGS1_k127_6134685_37	269799.Gmet_2399	3.467e-123	399.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,43UCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM MazG nucleotide pyrophosphohydrolase	mazG	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
REGS1_k127_6134685_63	443144.GM21_0467	8.66e-82	277.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,42RQX@68525|delta/epsilon subdivisions,2WNM1@28221|Deltaproteobacteria,43V7F@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_6134685_60	880072.Desac_0865	9.249e-84	312.0	COG2202@1|root,COG4585@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,1RB4Z@1224|Proteobacteria,42SHV@68525|delta/epsilon subdivisions,2X7QP@28221|Deltaproteobacteria,2MRJP@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,PAS_9
REGS1_k127_6134685_33	398767.Glov_2947	2.786e-130	421.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,42M13@68525|delta/epsilon subdivisions,2WPM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
REGS1_k127_6134685_5	316067.Geob_1877	3.958e-238	745.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,42M28@68525|delta/epsilon subdivisions,2WJPF@28221|Deltaproteobacteria,43TDN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
REGS1_k127_6134685_90	316067.Geob_3490	9.459e-35	137.0	COG4980@1|root,COG4980@2|Bacteria,1NEPD@1224|Proteobacteria,42WE2@68525|delta/epsilon subdivisions,2WRDT@28221|Deltaproteobacteria,43SRZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YtxH-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YtxH
REGS1_k127_6134685_29	269799.Gmet_0711	1.879e-133	434.0	COG2957@1|root,COG2957@2|Bacteria,1MX65@1224|Proteobacteria,42NAS@68525|delta/epsilon subdivisions,2WNAF@28221|Deltaproteobacteria,43RZU@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the agmatine deiminase family	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
REGS1_k127_6134685_23	316067.Geob_2344	2.109e-147	473.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,42M1Y@68525|delta/epsilon subdivisions,2WIPE@28221|Deltaproteobacteria,43S8K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Carbon-nitrogen hydrolase	aguB	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
REGS1_k127_6134685_11	443143.GM18_3430	2.926e-180	588.0	COG0840@1|root,COG2972@1|root,COG0840@2|Bacteria,COG2972@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,43SJD@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	mcp64H-2	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal
REGS1_k127_6134685_7	404380.Gbem_0567	1.991e-232	728.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
REGS1_k127_6134685_74	360104.CCC13826_0370	6.99e-55	196.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,42QU1@68525|delta/epsilon subdivisions,2YNVF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iIT341.HP1038	DHquinase_II
REGS1_k127_6134685_97	338963.Pcar_2130	8.377e-29	120.0	COG2018@1|root,COG2018@2|Bacteria,1NG1T@1224|Proteobacteria,42VP4@68525|delta/epsilon subdivisions,2WS9A@28221|Deltaproteobacteria,43V7Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_85	398767.Glov_1593	7.177e-40	161.0	COG4783@1|root,COG4783@2|Bacteria,1QZ64@1224|Proteobacteria,43CH3@68525|delta/epsilon subdivisions,2X7SA@28221|Deltaproteobacteria,43VYR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6134685_31	443143.GM18_1391	2.493e-131	428.0	COG0337@1|root,COG0337@2|Bacteria,1MUBK@1224|Proteobacteria,42MW5@68525|delta/epsilon subdivisions,2WJKR@28221|Deltaproteobacteria,43TT5@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
REGS1_k127_6134685_16	269799.Gmet_0976	2.901e-169	539.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,43U6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0976	Chorismate_synt
REGS1_k127_6134685_104	608538.HTH_1351	6.749e-16	81.0	COG1651@1|root,COG1651@2|Bacteria,2G51Z@200783|Aquificae	200783|Aquificae	O	PFAM Disulphide bond isomerase, DsbC G-like	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
REGS1_k127_6134685_1	443143.GM18_1387	2.31e-317	1018.0	COG0823@1|root,COG1470@1|root,COG4625@1|root,COG0823@2|Bacteria,COG1470@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	ko:K13669	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	DUF11,GT87,He_PIG,HemolysinCabind,PD40
REGS1_k127_6134685_6	404380.Gbem_1550	1.491e-237	768.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,43UJ4@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
REGS1_k127_6134685_95	443143.GM18_1384	1.816e-33	138.0	COG3168@1|root,COG3168@2|Bacteria,1NMC2@1224|Proteobacteria,42WTR@68525|delta/epsilon subdivisions,2WSTB@28221|Deltaproteobacteria,43VGT@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
REGS1_k127_6134685_67	443143.GM18_1383	9.045e-73	250.0	COG3167@1|root,COG3167@2|Bacteria,1MZZ4@1224|Proteobacteria,43B6P@68525|delta/epsilon subdivisions,2X6K9@28221|Deltaproteobacteria,43TSB@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
REGS1_k127_6134685_78	316067.Geob_3069	7.496e-53	193.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria,43UXE@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
REGS1_k127_6134685_22	443144.GM21_2669	2.094e-147	474.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,43UK6@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
REGS1_k127_6134685_100	404380.Gbem_1545	1.656e-22	98.0	COG1476@1|root,COG1476@2|Bacteria,1NB6T@1224|Proteobacteria,42VWK@68525|delta/epsilon subdivisions,2WRMY@28221|Deltaproteobacteria,43VV4@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_6171398_51	521011.Mpal_1148	1.917e-15	77.0	COG1924@1|root,arCOG02678@2157|Archaea,2XVMQ@28890|Euryarchaeota,2N9CS@224756|Methanomicrobia	28890|Euryarchaeota	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
REGS1_k127_6171398_15	645991.Sgly_1018	1.87e-144	469.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,2609U@186807|Peptococcaceae	186801|Clostridia	E	Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
REGS1_k127_6171398_25	316067.Geob_2492	7e-119	389.0	COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,42QRU@68525|delta/epsilon subdivisions,2WMNQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
REGS1_k127_6171398_28	754035.Mesau_03273	2.422e-97	326.0	COG0600@1|root,COG0600@2|Bacteria,1N4HG@1224|Proteobacteria,2TSTU@28211|Alphaproteobacteria,43PW1@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	BPD_transp_1
REGS1_k127_6171398_26	492774.JQMB01000013_gene3045	6.001e-106	353.0	COG0715@1|root,COG0715@2|Bacteria,1MV9S@1224|Proteobacteria,2TTIU@28211|Alphaproteobacteria,4BB63@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC transporter	-	-	-	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	NMT1
REGS1_k127_6171398_16	1120972.AUMH01000024_gene641	8.035e-144	477.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HE55@91061|Bacilli	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
REGS1_k127_6171398_9	1382304.JNIL01000001_gene1288	1.654e-164	535.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HESN@91061|Bacilli,279AB@186823|Alicyclobacillaceae	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran
REGS1_k127_6171398_42	645991.Sgly_2768	2.062e-35	138.0	COG0778@1|root,COG0778@2|Bacteria,1VIF2@1239|Firmicutes,24GUE@186801|Clostridia,262TQ@186807|Peptococcaceae	186801|Clostridia	C	PFAM Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_6171398_34	1111479.AXAR01000009_gene2431	4.302e-73	256.0	COG0491@1|root,COG0491@2|Bacteria,1V2VR@1239|Firmicutes,4HDAP@91061|Bacilli	91061|Bacilli	S	Metallo-beta-lactamase superfamily	glx2	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_6171398_21	1207063.P24_03555	2.284e-130	428.0	COG2807@1|root,COG2807@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_6171398_0	243231.GSU1198	1.766e-269	836.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria,43U5C@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
REGS1_k127_6171398_30	338966.Ppro_1702	2.364e-84	285.0	COG0084@1|root,COG2896@1|root,COG0084@2|Bacteria,COG2896@2|Bacteria,1MUC0@1224|Proteobacteria,42MMS@68525|delta/epsilon subdivisions,2WMUI@28221|Deltaproteobacteria,43TZ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Radical SAM domain protein	tatD	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_14,Radical_SAM,TatD_DNase
REGS1_k127_6171398_24	909663.KI867150_gene516	1.717e-121	404.0	COG1775@1|root,COG1775@2|Bacteria,1NNW9@1224|Proteobacteria,42PEQ@68525|delta/epsilon subdivisions,2WINV@28221|Deltaproteobacteria,2MR7Z@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
REGS1_k127_6171398_35	177439.DP2514	5.579e-62	222.0	COG1924@1|root,COG1924@2|Bacteria,1R6HU@1224|Proteobacteria,42PM0@68525|delta/epsilon subdivisions,2WJRP@28221|Deltaproteobacteria,2MHRM@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM BadF BadG BcrA BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
REGS1_k127_6171398_2	316067.Geob_2488	1.248e-247	770.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria,43U12@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metY-2	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_6171398_50	443143.GM18_3472	2.315e-17	85.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,42V8V@68525|delta/epsilon subdivisions,2WRKG@28221|Deltaproteobacteria,43VSE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	acylphosphatase activity	acyP	GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
REGS1_k127_6171398_48	706587.Desti_2883	2.763e-21	97.0	COG1254@1|root,COG1254@2|Bacteria,1QUKD@1224|Proteobacteria,42XEI@68525|delta/epsilon subdivisions,2WTAI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM acylphosphatase	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
REGS1_k127_6171398_10	316067.Geob_0441	1.07e-156	500.0	COG0301@1|root,COG0301@2|Bacteria,1N1R1@1224|Proteobacteria,42MQ9@68525|delta/epsilon subdivisions,2WJPN@28221|Deltaproteobacteria,43T42@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Thiamine biosynthesis protein (ThiI)	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,ThiI
REGS1_k127_6171398_4	316067.Geob_0796	5.893e-203	640.0	COG2873@1|root,COG2873@2|Bacteria,1NQME@1224|Proteobacteria,43DRR@68525|delta/epsilon subdivisions,2X70U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism	metY-3	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_6171398_46	269799.Gmet_1567	2.262e-24	103.0	COG2104@1|root,COG2104@2|Bacteria,1NHWM@1224|Proteobacteria,42X90@68525|delta/epsilon subdivisions,2WYF2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS-2	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_6171398_14	404380.Gbem_1980	6.185e-146	466.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,42NEC@68525|delta/epsilon subdivisions,2WK08@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	moeB1	-	2.7.7.80,2.8.1.11	ko:K21147	ko04122,map04122	-	R07459,R07461	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
REGS1_k127_6171398_38	316067.Geob_0799	1.772e-50	182.0	COG1310@1|root,COG1310@2|Bacteria,1N3TI@1224|Proteobacteria,42TY4@68525|delta/epsilon subdivisions,2WW9Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART Mov34 MPN PAD-1 family protein	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
REGS1_k127_6171398_8	269799.Gmet_1570	4.119e-166	527.0	COG2221@1|root,COG2221@2|Bacteria,1R5F8@1224|Proteobacteria,42PB3@68525|delta/epsilon subdivisions,2WKJR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,NIR_SIR,NIR_SIR_ferr
REGS1_k127_6171398_43	269799.Gmet_1571	1.792e-32	128.0	COG0425@1|root,COG0425@2|Bacteria,1NGCU@1224|Proteobacteria,42XTE@68525|delta/epsilon subdivisions,2WSIH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	tusA-1	-	-	-	-	-	-	-	-	-	-	-	TusA
REGS1_k127_6171398_19	316067.Geob_1979	4.139e-136	443.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,43SZM@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
REGS1_k127_6171398_6	316067.Geob_2506	7.62e-190	599.0	COG1168@1|root,COG1168@2|Bacteria,1MY33@1224|Proteobacteria,42M6F@68525|delta/epsilon subdivisions,2WK37@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_6171398_11	443144.GM21_0256	1.36e-156	505.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,42Q77@68525|delta/epsilon subdivisions,2WK3N@28221|Deltaproteobacteria,43SBF@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.7.1,1.8.1.2,1.8.7.1	ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
REGS1_k127_6171398_17	398767.Glov_2685	4.711e-140	456.0	COG1929@1|root,COG1929@2|Bacteria,1MVG9@1224|Proteobacteria,42MRF@68525|delta/epsilon subdivisions,2WNGJ@28221|Deltaproteobacteria,43UUK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
REGS1_k127_6171398_5	269799.Gmet_0348	1.087e-202	657.0	COG0308@1|root,COG0308@2|Bacteria,1PEPK@1224|Proteobacteria,42NJ8@68525|delta/epsilon subdivisions,2WM57@28221|Deltaproteobacteria,43TCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0348	Peptidase_M1
REGS1_k127_6171398_33	316067.Geob_3103	1.427e-73	259.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WMNG@28221|Deltaproteobacteria,43UNW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg
REGS1_k127_6171398_49	404380.Gbem_2740	5.737e-19	102.0	COG1629@1|root,COG4886@1|root,COG4771@2|Bacteria,COG4886@2|Bacteria,1P67X@1224|Proteobacteria,4323Z@68525|delta/epsilon subdivisions,2WXVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6171398_56	1087481.AGFX01000048_gene2614	8.758e-06	59.0	COG0737@1|root,COG1361@1|root,COG3507@1|root,COG4733@1|root,COG0737@2|Bacteria,COG1361@2|Bacteria,COG3507@2|Bacteria,COG4733@2|Bacteria,1V7PQ@1239|Firmicutes,4IUC5@91061|Bacilli,277JF@186822|Paenibacillaceae	91061|Bacilli	G	Fibronectin type III domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,SLH,fn3
REGS1_k127_6171398_44	269799.Gmet_1108	2.568e-30	123.0	2EKQ7@1|root,33EDZ@2|Bacteria,1NHK0@1224|Proteobacteria,42VJ3@68525|delta/epsilon subdivisions,2WRIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2845)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2845
REGS1_k127_6171398_52	1121448.DGI_0425	6.492e-13	72.0	2EHUE@1|root,33BK1@2|Bacteria,1QTGN@1224|Proteobacteria,4369K@68525|delta/epsilon subdivisions,2X0U9@28221|Deltaproteobacteria,2MDF0@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6171398_45	1000565.METUNv1_01996	4.304e-25	116.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,2KWND@206389|Rhodocyclales	206389|Rhodocyclales	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
REGS1_k127_6171398_13	264198.Reut_A1978	7.292e-154	492.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2VIQZ@28216|Betaproteobacteria,1K1GN@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Sulfate ABC transporter, periplasmic sulfate-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
REGS1_k127_6171398_18	404380.Gbem_1737	2.859e-139	446.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,42NRU@68525|delta/epsilon subdivisions,2X7CC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	cysU	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
REGS1_k127_6171398_20	443143.GM18_1687	2.392e-133	430.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,42ND8@68525|delta/epsilon subdivisions,2WN93@28221|Deltaproteobacteria,43VJQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
REGS1_k127_6171398_12	316067.Geob_1654	1.043e-154	495.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,42QH0@68525|delta/epsilon subdivisions,2WJY7@28221|Deltaproteobacteria,43UNJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
REGS1_k127_6171398_27	443143.GM18_1812	6.497e-105	346.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,42PUJ@68525|delta/epsilon subdivisions,2WM9G@28221|Deltaproteobacteria,43S2G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
REGS1_k127_6171398_7	316067.Geob_0805	9.79e-188	588.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,42NYE@68525|delta/epsilon subdivisions,2WK6Q@28221|Deltaproteobacteria,43SCQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	TIGRFAM sulfate adenylyltransferase, small subunit	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
REGS1_k127_6171398_1	316067.Geob_0806	1.107e-247	774.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,42N3C@68525|delta/epsilon subdivisions,2WKCB@28221|Deltaproteobacteria,43TG2@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_6171398_39	545695.TREAZ_1721	5.719e-48	183.0	COG1348@1|root,COG1348@2|Bacteria,2JA1R@203691|Spirochaetes	203691|Spirochaetes	P	Belongs to the NifH BchL ChlL family	-	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
REGS1_k127_6171398_31	1304885.AUEY01000017_gene3733	9.175e-82	276.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1N47P@1224|Proteobacteria,42W9J@68525|delta/epsilon subdivisions,2WSBM@28221|Deltaproteobacteria,2MKZR@213118|Desulfobacterales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3
REGS1_k127_6171398_47	323259.Mhun_0966	1.866e-21	100.0	COG2703@1|root,arCOG06577@2157|Archaea,2XX8P@28890|Euryarchaeota,2NBIH@224756|Methanomicrobia	224756|Methanomicrobia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_6171398_53	717231.Flexsi_0628	3.649e-08	63.0	COG2204@1|root,COG2204@2|Bacteria,2GF2T@200930|Deferribacteres	200930|Deferribacteres	T	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_6171398_55	338963.Pcar_0040	3.125e-06	57.0	COG0745@1|root,COG0745@2|Bacteria	338963.Pcar_0040|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6171398_57	1144310.PMI07_001442	1.483e-05	47.0	COG2801@1|root,COG2801@2|Bacteria,1N207@1224|Proteobacteria,2UEQQ@28211|Alphaproteobacteria,4BC7V@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,HTH_32,rve,rve_3
REGS1_k127_6171398_29	269799.Gmet_2987	7.621e-92	310.0	COG1606@1|root,COG1606@2|Bacteria,1R7UZ@1224|Proteobacteria,42Q6V@68525|delta/epsilon subdivisions,2WKIM@28221|Deltaproteobacteria,43TMR@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM asparagine synthase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
REGS1_k127_6171398_3	316067.Geob_1088	1.701e-242	756.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WJ1M@28221|Deltaproteobacteria,43S7W@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls-2	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
REGS1_k127_6171398_32	269799.Gmet_0302	1.471e-74	252.0	COG2258@1|root,COG2258@2|Bacteria,1RKJ9@1224|Proteobacteria,42TCU@68525|delta/epsilon subdivisions,2WP56@28221|Deltaproteobacteria,43UTW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0302	MOSC
REGS1_k127_6171398_22	398767.Glov_0892	4.057e-127	421.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,42NBV@68525|delta/epsilon subdivisions,2WK0F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
REGS1_k127_6171398_36	316067.Geob_2484	2.124e-61	215.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
REGS1_k127_6171398_23	316067.Geob_2483	2.614e-125	409.0	COG1456@1|root,COG1456@2|Bacteria,1R6BH@1224|Proteobacteria,42NKF@68525|delta/epsilon subdivisions,2WJ72@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel	-	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
REGS1_k127_6171398_40	443144.GM21_3090	1.32e-38	145.0	COG1148@1|root,COG1148@2|Bacteria,1N9EA@1224|Proteobacteria,42VBD@68525|delta/epsilon subdivisions,2WR6S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S binding domain	frx-1	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_6236536_3	338966.Ppro_2708	1.108e-224	710.0	COG5316@1|root,COG5316@2|Bacteria,1N0IJ@1224|Proteobacteria,43BYT@68525|delta/epsilon subdivisions,2WMTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	N-terminal domain of unknown function (DUF4140)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139,DUF4140
REGS1_k127_6236536_14	159087.Daro_2349	1.188e-48	179.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,2KW5U@206389|Rhodocyclales	206389|Rhodocyclales	O	FKBP-type peptidyl-prolyl cis-trans	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_6236536_8	338966.Ppro_2113	1.368e-122	401.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,42M13@68525|delta/epsilon subdivisions,2WQAC@28221|Deltaproteobacteria,43T6M@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
REGS1_k127_6236536_10	269799.Gmet_3034	1.439e-92	310.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2WRKW@28221|Deltaproteobacteria,43T2V@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
REGS1_k127_6236536_4	316067.Geob_1667	8.803e-150	487.0	COG0585@1|root,COG0585@2|Bacteria,1MXHD@1224|Proteobacteria,42P4E@68525|delta/epsilon subdivisions,2WN09@28221|Deltaproteobacteria,43SVP@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
REGS1_k127_6236536_16	269799.Gmet_3032	1.513e-27	117.0	COG4327@1|root,COG4327@2|Bacteria,1P0U5@1224|Proteobacteria,4322M@68525|delta/epsilon subdivisions,2WX31@28221|Deltaproteobacteria,43VHT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4212)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4212
REGS1_k127_6236536_2	243231.GSU0518	4.759e-226	710.0	COG4147@1|root,COG4147@2|Bacteria,1QXN2@1224|Proteobacteria,43C45@68525|delta/epsilon subdivisions,2WK6N@28221|Deltaproteobacteria,43TZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Sodium:solute symporter family	aplD	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	-	SSF
REGS1_k127_6236536_15	316067.Geob_1670	2.28e-41	168.0	COG2905@1|root,COG2905@2|Bacteria	2|Bacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	-	-	2.7.7.7	ko:K02342,ko:K07182	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
REGS1_k127_6236536_7	243231.GSU0516	3.698e-132	425.0	COG1082@1|root,COG1082@2|Bacteria,1RGEK@1224|Proteobacteria,42S9K@68525|delta/epsilon subdivisions,2WNFH@28221|Deltaproteobacteria,43TC8@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
REGS1_k127_6236536_9	269799.Gmet_2466	2.355e-116	386.0	COG3267@1|root,COG3271@1|root,COG3409@1|root,COG3267@2|Bacteria,COG3271@2|Bacteria,COG3409@2|Bacteria,1MU3G@1224|Proteobacteria,42N7S@68525|delta/epsilon subdivisions,2WMBC@28221|Deltaproteobacteria,43SAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	MU	SMART AAA ATPase	exeA	-	-	ko:K02450	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	AAA_22,PG_binding_1
REGS1_k127_6236536_17	443143.GM18_1084	4.813e-23	106.0	2DRAW@1|root,33B0D@2|Bacteria,1NNRE@1224|Proteobacteria,42X1M@68525|delta/epsilon subdivisions,2WSKK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Type II secretion system protein B	-	-	-	ko:K02451	-	M00331	-	-	ko00000,ko00002,ko02044	9.B.42	-	-	T2SSB
REGS1_k127_6236536_12	269799.Gmet_3028	1.061e-70	241.0	COG0589@1|root,COG0589@2|Bacteria,1NP95@1224|Proteobacteria,42ZXU@68525|delta/epsilon subdivisions,2WVF2@28221|Deltaproteobacteria,43UVA@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Belongs to the universal stress protein A family	usp-1	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_6236536_6	443144.GM21_0669	3.598e-140	449.0	COG1414@1|root,COG1414@2|Bacteria,1MUNW@1224|Proteobacteria,42M2F@68525|delta/epsilon subdivisions,2WKUG@28221|Deltaproteobacteria,43THQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	regulatory protein IclR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
REGS1_k127_6236536_11	243231.GSU0513	5.067e-71	249.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,42RI5@68525|delta/epsilon subdivisions,2WPDF@28221|Deltaproteobacteria,43V0X@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
REGS1_k127_6236536_5	269799.Gmet_3024	9.592e-148	477.0	COG2309@1|root,COG2309@2|Bacteria,1PRI7@1224|Proteobacteria,42R5J@68525|delta/epsilon subdivisions,2WMQA@28221|Deltaproteobacteria,43U01@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Thermophilic metalloprotease (M29)	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
REGS1_k127_6236536_0	243231.GSU0510	0.0	1185.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1MU2H@1224|Proteobacteria,42M6X@68525|delta/epsilon subdivisions,2X6YD@28221|Deltaproteobacteria,43TFJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	sfrB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_20,NADH_4Fe-4S,Pyr_redox_2
REGS1_k127_6236536_1	316067.Geob_1608	2.145e-316	986.0	COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,43BP2@68525|delta/epsilon subdivisions,2WK8X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	molybdopterin oxidoreductase Fe4S4 region	sfrA	-	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4_10,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
REGS1_k127_6259027_13	404380.Gbem_0164	2.464e-66	229.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,43U1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
REGS1_k127_6259027_15	443144.GM21_0146	2.404e-47	170.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,43VAN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
REGS1_k127_6259027_14	316067.Geob_1244	1.542e-47	172.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,43SNE@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
REGS1_k127_6259027_18	243231.GSU0845	4.957e-39	147.0	COG2146@1|root,COG2146@2|Bacteria,1NPNB@1224|Proteobacteria,4325B@68525|delta/epsilon subdivisions,2WYC1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Rieske 2Fe-2S	-	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,Rieske_2
REGS1_k127_6259027_2	316067.Geob_1241	1.07e-292	903.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,43TM0@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	TIGRFAM ribonuclease, Rne Rng family	cafA	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
REGS1_k127_6259027_1	316067.Geob_1240	0.0	1111.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,43UIU@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
REGS1_k127_6259027_17	404380.Gbem_0156	3.25e-40	153.0	2EAWF@1|root,334XP@2|Bacteria,1NKSU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6259027_16	269799.Gmet_3188	1.365e-45	169.0	2EAWF@1|root,334XP@2|Bacteria,1NKSU@1224|Proteobacteria,430YX@68525|delta/epsilon subdivisions,2WW3M@28221|Deltaproteobacteria,43V9A@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6259027_9	243231.GSU3246	2.23e-105	344.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WNT4@28221|Deltaproteobacteria,43T04@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	prx-2	-	1.11.1.15	ko:K03386,ko:K20011	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
REGS1_k127_6259027_8	443143.GM18_0132	2.002e-116	379.0	COG1145@1|root,COG1145@2|Bacteria,1PW12@1224|Proteobacteria,42MZ9@68525|delta/epsilon subdivisions,2WN0W@28221|Deltaproteobacteria,43SWA@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
REGS1_k127_6259027_19	243231.GSU3248	1.648e-38	147.0	2EU5A@1|root,33MMY@2|Bacteria,1NE4I@1224|Proteobacteria,42WER@68525|delta/epsilon subdivisions,2WRAE@28221|Deltaproteobacteria,43VD3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Nitrous oxide-stimulated promoter	-	-	-	-	-	-	-	-	-	-	-	-	YgbA_NO
REGS1_k127_6259027_7	243231.GSU3250	8.312e-131	433.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,43TZA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
REGS1_k127_6259027_5	269799.Gmet_3070	1.378e-180	569.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,43TQZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
REGS1_k127_6259027_3	243231.GSU0489	2.637e-255	795.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,43SC2@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
REGS1_k127_6259027_12	713587.THITH_11685	1.215e-69	251.0	COG3058@1|root,COG3058@2|Bacteria,1NK06@1224|Proteobacteria,1RQC4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Necessary for formate dehydrogenase activity	fdhE	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008199,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0051604,GO:0055114,GO:0071704,GO:1901564	-	ko:K02380	-	-	-	-	ko00000	-	-	-	FdhE
REGS1_k127_6259027_11	1458275.AZ34_02910	2.617e-84	284.0	COG2864@1|root,COG2864@2|Bacteria,1MXFQ@1224|Proteobacteria,2VKTA@28216|Betaproteobacteria,4AB36@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM Formate dehydrogenase, gamma subunit	fdoI	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
REGS1_k127_6259027_6	1231391.AMZF01000009_gene1759	2.869e-150	479.0	COG0437@1|root,COG0437@2|Bacteria,1QUMM@1224|Proteobacteria,2WHXZ@28216|Betaproteobacteria	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K07307	ko00920,map00920	-	R09501	RC02555	ko00000,ko00001,ko02000	5.A.3.3	-	-	Fer4_11
REGS1_k127_6259027_0	159087.Daro_1818	0.0	1320.0	COG0243@1|root,COG3383@1|root,COG0243@2|Bacteria,COG3383@2|Bacteria,1MW3N@1224|Proteobacteria,2VJG2@28216|Betaproteobacteria,2KU82@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
REGS1_k127_6259027_10	159087.Daro_1819	1.431e-97	321.0	COG0243@1|root,COG0243@2|Bacteria,1MWPS@1224|Proteobacteria,2VHYH@28216|Betaproteobacteria,2KYCY@206389|Rhodocyclales	206389|Rhodocyclales	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin
REGS1_k127_6259027_4	338966.Ppro_1061	4.091e-181	571.0	COG1607@1|root,COG1607@2|Bacteria,1Q9RF@1224|Proteobacteria,42Q5P@68525|delta/epsilon subdivisions,2WJY5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_6281714_3	1121918.ARWE01000001_gene3176	2.282e-17	87.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
REGS1_k127_6281714_1	269799.Gmet_1015	1.295e-94	325.0	2C1UW@1|root,32XSR@2|Bacteria,1N37G@1224|Proteobacteria	1224|Proteobacteria	S	YfdX protein	-	-	-	-	-	-	-	-	-	-	-	-	YfdX
REGS1_k127_6281714_2	316067.Geob_2338	3.096e-34	134.0	28XS9@1|root,2ZJNQ@2|Bacteria	2|Bacteria	P	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_6281714_0	269799.Gmet_3299	5.141e-97	332.0	292UM@1|root,338CY@2|Bacteria,1NAKE@1224|Proteobacteria,42WM1@68525|delta/epsilon subdivisions,2WS0V@28221|Deltaproteobacteria,43T5N@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6291599_8	247490.KSU1_C0374	1.387e-56	208.0	28PU4@1|root,2ZCF6@2|Bacteria,2J30W@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6291599_0	316067.Geob_1310	8.187e-186	593.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WTPN@28221|Deltaproteobacteria,43TVD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Belongs to the DEAD box helicase family	rhlE-1	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
REGS1_k127_6291599_3	316067.Geob_0886	1.51e-75	263.0	2DRH1@1|root,33BQ8@2|Bacteria,1NM8D@1224|Proteobacteria,42XND@68525|delta/epsilon subdivisions,2WSKN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	gspN	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
REGS1_k127_6291599_1	316067.Geob_0888	1.077e-109	369.0	COG3297@1|root,COG3297@2|Bacteria	2|Bacteria	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
REGS1_k127_6291599_2	398767.Glov_1274	1.174e-85	297.0	COG3156@1|root,COG3156@2|Bacteria,1N9I4@1224|Proteobacteria,42V0N@68525|delta/epsilon subdivisions,2WRR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	PFAM General secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
REGS1_k127_6291599_7	316067.Geob_0890	3.695e-60	217.0	COG4795@1|root,COG4795@2|Bacteria,1NPEC@1224|Proteobacteria,42WZG@68525|delta/epsilon subdivisions,2WSPB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
REGS1_k127_6291599_10	316067.Geob_0891	5.256e-35	138.0	COG2165@1|root,COG2165@2|Bacteria,1NH8A@1224|Proteobacteria,43CDD@68525|delta/epsilon subdivisions,2X7P8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	gspI	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
REGS1_k127_6291599_9	316067.Geob_0892	1.432e-38	152.0	COG4970@1|root,COG4970@2|Bacteria,1NA3K@1224|Proteobacteria,42XEU@68525|delta/epsilon subdivisions,2WSX4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Prokaryotic N-terminal methylation motif	gspH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
REGS1_k127_6291599_4	398767.Glov_1278	1.265e-71	244.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_6291599_5	316067.Geob_0894	5.157e-68	235.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
REGS1_k127_6303581_11	765912.Thimo_3354	1.216e-06	50.0	2ER5G@1|root,33IR2@2|Bacteria,1NQCM@1224|Proteobacteria,1SJHN@1236|Gammaproteobacteria,1WZT4@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6303581_7	398767.Glov_2577	4.65e-36	139.0	2E8BS@1|root,334EE@2|Bacteria,1N75E@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6303581_5	316067.Geob_1283	9.767e-85	304.0	COG1361@1|root,COG1404@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,1QUXB@1224|Proteobacteria	1224|Proteobacteria	U	6-phosphogluconolactonase activity	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,Cadherin_3,DUF11,DUF4347,He_PIG,PATR
REGS1_k127_6303581_0	269799.Gmet_2372	8.288e-250	774.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,42MS9@68525|delta/epsilon subdivisions,2WJMS@28221|Deltaproteobacteria,43U3Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
REGS1_k127_6303581_1	443144.GM21_3263	4.685e-244	777.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,43UC4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Metal-dependent phosphohydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
REGS1_k127_6303581_8	1125863.JAFN01000001_gene54	3.75e-27	117.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42W3M@68525|delta/epsilon subdivisions,2WRMB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	Cupin_2,UPF0054
REGS1_k127_6303581_4	243231.GSU2283	4.018e-90	302.0	COG0671@1|root,COG0818@1|root,COG0671@2|Bacteria,COG0818@2|Bacteria,1Q5TS@1224|Proteobacteria,42SZA@68525|delta/epsilon subdivisions,2WPDT@28221|Deltaproteobacteria,43T24@69541|Desulfuromonadales	28221|Deltaproteobacteria	IM	Prokaryotic diacylglycerol kinase	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2369	DAGK_prokar,PAP2
REGS1_k127_6303581_3	316067.Geob_3095	9.019e-112	369.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42QX1@68525|delta/epsilon subdivisions,2WMNH@28221|Deltaproteobacteria,43TQD@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
REGS1_k127_6303581_2	316067.Geob_3094	1.079e-185	596.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,43TVN@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
REGS1_k127_6303581_9	903818.KI912268_gene2810	4.899e-20	107.0	COG3210@1|root,COG4412@1|root,COG3210@2|Bacteria,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	ko:K20276,ko:K21449	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	1.B.40.2	-	-	Big_2,CARDB,Cadherin-like,Peptidase_M30,SLH,fn3
REGS1_k127_6303581_6	864051.BurJ1DRAFT_3700	3.097e-83	314.0	COG0726@1|root,COG0823@1|root,COG2911@1|root,COG2931@1|root,COG3210@1|root,COG3420@1|root,COG0726@2|Bacteria,COG0823@2|Bacteria,COG2911@2|Bacteria,COG2931@2|Bacteria,COG3210@2|Bacteria,COG3420@2|Bacteria,1MU7T@1224|Proteobacteria,2WI67@28216|Betaproteobacteria,1KMDS@119065|unclassified Burkholderiales	28216|Betaproteobacteria	MQU	Domain of unknown function (DUF4347)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4347
REGS1_k127_6303581_10	105425.BBPL01000018_gene27	3.62e-17	98.0	COG3291@1|root,COG3291@2|Bacteria,2I55I@201174|Actinobacteria	201174|Actinobacteria	S	Putative Ig domain	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG
REGS1_k127_6321034_12	404380.Gbem_2519	7.596e-36	136.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,43UMB@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Iron-storage protein	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
REGS1_k127_6321034_7	316067.Geob_3495	2.969e-92	317.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RVN@68525|delta/epsilon subdivisions,2WNJW@28221|Deltaproteobacteria,43SP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	SurA N-terminal domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_6321034_0	398767.Glov_2549	0.0	2112.0	COG1038@1|root,COG1038@2|Bacteria,1NW9R@1224|Proteobacteria,43BKE@68525|delta/epsilon subdivisions,2X6YE@28221|Deltaproteobacteria,43UBK@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
REGS1_k127_6321034_14	391612.CY0110_27475	3.015e-19	91.0	2C6B2@1|root,3318T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6321034_13	56110.Oscil6304_0817	8.944e-30	120.0	COG2929@1|root,COG2929@2|Bacteria,1G92M@1117|Cyanobacteria,1HCTJ@1150|Oscillatoriales	1117|Cyanobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
REGS1_k127_6321034_11	477974.Daud_0415	1.261e-39	151.0	COG2402@1|root,COG2402@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
REGS1_k127_6321034_10	1121918.ARWE01000001_gene682	3.73e-44	175.0	COG0589@1|root,COG0589@2|Bacteria,1QM7A@1224|Proteobacteria,42ZVW@68525|delta/epsilon subdivisions,2WVEM@28221|Deltaproteobacteria,43V1I@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_6321034_5	1125863.JAFN01000001_gene167	3.364e-94	316.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42N2W@68525|delta/epsilon subdivisions,2WJRB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
REGS1_k127_6321034_3	1125863.JAFN01000001_gene166	1.874e-115	383.0	COG0683@1|root,COG0683@2|Bacteria,1MV5T@1224|Proteobacteria,42ND9@68525|delta/epsilon subdivisions,2WK5F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_6321034_8	198467.NP92_04885	3.949e-90	310.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HBB8@91061|Bacilli,21VU1@150247|Anoxybacillus	91061|Bacilli	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_6321034_4	1307436.PBF_09962	2.475e-99	332.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HEZ3@91061|Bacilli,1ZQ8V@1386|Bacillus	91061|Bacilli	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_6321034_6	1125863.JAFN01000001_gene162	1.574e-92	311.0	COG0411@1|root,COG0411@2|Bacteria,1MUTY@1224|Proteobacteria,42NI5@68525|delta/epsilon subdivisions,2WIN8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_6321034_9	243231.GSU0379	4.088e-70	247.0	COG0095@1|root,COG0095@2|Bacteria,1RI3T@1224|Proteobacteria,42SQP@68525|delta/epsilon subdivisions,2WQH2@28221|Deltaproteobacteria,43SNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Biotin/lipoate A/B protein ligase family	lplA	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
REGS1_k127_6321034_15	404380.Gbem_1379	2.24e-18	87.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria,43S75@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Transketolase, thiamine diphosphate binding domain	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
REGS1_k127_6321034_1	443143.GM18_3100	1.114e-150	492.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,42M3M@68525|delta/epsilon subdivisions,2WJ8B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
REGS1_k127_6321034_2	398767.Glov_2671	8.468e-147	467.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,42MR9@68525|delta/epsilon subdivisions,2WIP3@28221|Deltaproteobacteria,43TFR@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM glycine cleavage system P-protein	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
REGS1_k127_6371823_5	316067.Geob_1834	5.351e-09	64.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_6371823_2	1123277.KB893216_gene4852	6.793e-66	235.0	COG1262@1|root,COG1262@2|Bacteria,4NEUZ@976|Bacteroidetes,47QN7@768503|Cytophagia	976|Bacteroidetes	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_6371823_3	1156937.MFUM_1010089	2.309e-37	149.0	COG4798@1|root,COG4798@2|Bacteria,46T4I@74201|Verrucomicrobia,37GDY@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	S	Met-10+ like-protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
REGS1_k127_6371823_1	398767.Glov_1169	2.319e-74	258.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria,42MAT@68525|delta/epsilon subdivisions,2WKY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
REGS1_k127_6371823_0	639282.DEFDS_0296	5.733e-76	265.0	COG1262@1|root,COG1262@2|Bacteria,2GG48@200930|Deferribacteres	200930|Deferribacteres	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
REGS1_k127_6371823_4	316067.Geob_1834	1.439e-26	121.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_6378292_6	243231.GSU0102	1.05e-127	416.0	COG3276@1|root,COG3276@2|Bacteria,1MWXH@1224|Proteobacteria,42M49@68525|delta/epsilon subdivisions,2WJ5G@28221|Deltaproteobacteria,43TPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Elongation factor SelB winged helix 3	selB	-	-	ko:K03833	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3
REGS1_k127_6378292_14	338966.Ppro_2816	1.429e-40	152.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,42UXJ@68525|delta/epsilon subdivisions,2WQ0I@28221|Deltaproteobacteria,43VAF@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
REGS1_k127_6378292_18	338966.Ppro_2943	1.542e-24	107.0	COG0607@1|root,COG0607@2|Bacteria,1PEZQ@1224|Proteobacteria,42X5U@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_6378292_7	269799.Gmet_0584	3.87e-125	420.0	COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_7,TPR_8
REGS1_k127_6378292_9	269799.Gmet_0265	1.116e-57	207.0	COG1051@1|root,COG1051@2|Bacteria,1RJAP@1224|Proteobacteria,42SFP@68525|delta/epsilon subdivisions,2WPBX@28221|Deltaproteobacteria,43SJP@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_6378292_5	269799.Gmet_1727	1.009e-154	493.0	COG0667@1|root,COG1145@1|root,COG0667@2|Bacteria,COG1145@2|Bacteria,1QY8Q@1224|Proteobacteria,43CAJ@68525|delta/epsilon subdivisions,2X26I@28221|Deltaproteobacteria,43T23@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4
REGS1_k127_6378292_10	443144.GM21_1019	1.835e-47	173.0	COG3514@1|root,COG3514@2|Bacteria,1PSWP@1224|Proteobacteria,4326T@68525|delta/epsilon subdivisions,2WYGR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
REGS1_k127_6378292_24	1267535.KB906767_gene5248	1.777e-06	55.0	COG2929@1|root,COG2929@2|Bacteria,3Y5X2@57723|Acidobacteria,2JK3U@204432|Acidobacteriia	204432|Acidobacteriia	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
REGS1_k127_6378292_0	243231.GSU0913	1.371e-281	877.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,43T4P@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter C-terminal domain	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
REGS1_k127_6378292_23	1110697.NCAST_34_06050	1.276e-06	57.0	2EI4I@1|root,33BVW@2|Bacteria,2IQR6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6378292_19	1458275.AZ34_12560	9.577e-23	103.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,2WF7M@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_6378292_8	269799.Gmet_0807	1.95e-103	346.0	COG1600@1|root,COG1600@2|Bacteria,1RAYI@1224|Proteobacteria,42R4W@68525|delta/epsilon subdivisions,2WK0B@28221|Deltaproteobacteria,43S8Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6378292_3	443144.GM21_1538	9.172e-187	591.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42SFR@68525|delta/epsilon subdivisions,2WPY1@28221|Deltaproteobacteria,43U4Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
REGS1_k127_6378292_17	646529.Desaci_0179	8.109e-28	117.0	2A154@1|root,30PAZ@2|Bacteria,1V68U@1239|Firmicutes,24J10@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
REGS1_k127_6378292_11	443143.GM18_1267	4.327e-46	168.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3,HTH_31
REGS1_k127_6378292_12	404380.Gbem_1907	1.113e-42	161.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria	1224|Proteobacteria	L	Plasmid maintenance system killer	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
REGS1_k127_6378292_1	290315.Clim_0593	5.614e-230	717.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
REGS1_k127_6378292_2	243231.GSU0012	7.867e-224	702.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria,43SUB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
REGS1_k127_6378292_27	264462.Bd2274	0.000941	51.0	2FFSJ@1|root,347PR@2|Bacteria,1P3N4@1224|Proteobacteria,431V5@68525|delta/epsilon subdivisions,2MUB9@213481|Bdellovibrionales,2WWMJ@28221|Deltaproteobacteria	213481|Bdellovibrionales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6378292_26	1234664.AMRO01000076_gene2439	8.725e-05	54.0	COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1WEHB@129337|Geobacillus	91061|Bacilli	CO	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_6378292_16	1121405.dsmv_2958	1.584e-29	125.0	COG4314@1|root,COG4314@2|Bacteria,1N43A@1224|Proteobacteria,42U7U@68525|delta/epsilon subdivisions,2WQYI@28221|Deltaproteobacteria,2MMFG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
REGS1_k127_6378292_15	1121405.dsmv_2958	4.53e-33	134.0	COG4314@1|root,COG4314@2|Bacteria,1N43A@1224|Proteobacteria,42U7U@68525|delta/epsilon subdivisions,2WQYI@28221|Deltaproteobacteria,2MMFG@213118|Desulfobacterales	28221|Deltaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
REGS1_k127_6378292_13	335543.Sfum_2816	1.514e-41	159.0	COG4314@1|root,COG4314@2|Bacteria,1N43A@1224|Proteobacteria,42U7U@68525|delta/epsilon subdivisions,2X378@28221|Deltaproteobacteria,2MS9C@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	NosL	-	-	-	-	-	-	-	-	-	-	-	-	NosL
REGS1_k127_6378292_4	269799.Gmet_0058	4.923e-177	558.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria,43U6Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C
REGS1_k127_6417367_1	1121918.ARWE01000001_gene1622	4.52e-202	636.0	COG2199@1|root,COG3829@1|root,COG4191@1|root,COG2199@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	4.6.1.2	ko:K01769,ko:K11959	ko00230,ko02010,map00230,map02010	M00323	R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	GAF_2,GGDEF,HATPase_c,HTH_8,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_6417367_0	1121918.ARWE01000001_gene1623	1.408e-293	913.0	COG3290@1|root,COG3437@1|root,COG3290@2|Bacteria,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2X75V@28221|Deltaproteobacteria,43UV8@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
REGS1_k127_6417367_3	1121918.ARWE01000001_gene1622	4.794e-66	243.0	COG2199@1|root,COG3829@1|root,COG4191@1|root,COG2199@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	4.6.1.2	ko:K01769,ko:K11959	ko00230,ko02010,map00230,map02010	M00323	R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	GAF_2,GGDEF,HATPase_c,HTH_8,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_6417367_4	316067.Geob_3787	5.795e-62	219.0	COG1633@1|root,COG1633@2|Bacteria,1RM4Q@1224|Proteobacteria,42SRM@68525|delta/epsilon subdivisions,2WP47@28221|Deltaproteobacteria,43SJC@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_6417367_5	1297742.A176_00790	3.252e-08	56.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
REGS1_k127_6417367_2	357804.Ping_2504	3.859e-97	320.0	COG2201@1|root,COG2201@2|Bacteria,1QJYZ@1224|Proteobacteria,1S01C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	PFAM CheB methylesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest
REGS1_k127_6475165_5	316067.Geob_0952	4.817e-38	145.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,43TH3@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
REGS1_k127_6475165_1	316067.Geob_0953	2.353e-122	399.0	COG1852@1|root,COG1852@2|Bacteria,1RAI2@1224|Proteobacteria,42QUD@68525|delta/epsilon subdivisions,2WMQ5@28221|Deltaproteobacteria,43STT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function DUF116	-	-	-	ko:K09729	-	-	-	-	ko00000	-	-	-	DUF116
REGS1_k127_6475165_2	1232410.KI421428_gene1000	1.904e-92	309.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2WNTB@28221|Deltaproteobacteria,43U3Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	truC	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
REGS1_k127_6475165_0	269799.Gmet_0270	1.784e-150	485.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42MZS@68525|delta/epsilon subdivisions,2WIQP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	aromatic amino acid beta-eliminating lyase threonine aldolase	ltaA	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
REGS1_k127_6475165_4	316067.Geob_0955	2.592e-38	147.0	2DQTP@1|root,338M6@2|Bacteria,1NA5P@1224|Proteobacteria,42WPZ@68525|delta/epsilon subdivisions,2WRZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6475165_3	316067.Geob_0956	5.52e-85	293.0	COG0791@1|root,COG0791@2|Bacteria,1NRCV@1224|Proteobacteria,42YTE@68525|delta/epsilon subdivisions,2WUEN@28221|Deltaproteobacteria,43U28@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6506494_5	269799.Gmet_0940	5.075e-54	193.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,43U0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_6506494_2	243231.GSU2065	1.078e-129	419.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,42MP8@68525|delta/epsilon subdivisions,2WKMR@28221|Deltaproteobacteria,43SZE@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
REGS1_k127_6506494_0	243231.GSU2064	3.641e-197	629.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
REGS1_k127_6506494_6	316067.Geob_1673	6.677e-45	167.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF559
REGS1_k127_6506494_4	443144.GM21_1774	8.292e-78	262.0	COG1246@1|root,COG1246@2|Bacteria,1RHT7@1224|Proteobacteria,42SGE@68525|delta/epsilon subdivisions,2WP91@28221|Deltaproteobacteria,43UUJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Acetyltransferase (GNAT) domain	argA	-	2.3.1.1	ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0946	Acetyltransf_1,Acetyltransf_7
REGS1_k127_6506494_1	269799.Gmet_0947	1.509e-156	505.0	COG0312@1|root,COG0312@2|Bacteria,1MUVW@1224|Proteobacteria,42RID@68525|delta/epsilon subdivisions,2WN9N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase U62 modulator of DNA gyrase	pmbA	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_6506494_3	316067.Geob_1874	2.25e-82	279.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,43SV5@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
REGS1_k127_6545081_2	517418.Ctha_0347	9.077e-81	274.0	COG1150@1|root,COG1150@2|Bacteria,1FDMP@1090|Chlorobi	1090|Chlorobi	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
REGS1_k127_6545081_0	517418.Ctha_0346	1.327e-110	365.0	COG0543@1|root,COG0543@2|Bacteria,1FDP4@1090|Chlorobi	1090|Chlorobi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
REGS1_k127_6545081_1	517418.Ctha_0345	1.182e-86	293.0	COG1941@1|root,COG1941@2|Bacteria,1FDE2@1090|Chlorobi	1090|Chlorobi	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
REGS1_k127_6599991_0	269799.Gmet_0940	0.0	1115.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42N22@68525|delta/epsilon subdivisions,2WIMH@28221|Deltaproteobacteria,43U0M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_6599991_1	269799.Gmet_0939	1.17e-213	672.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,43TE2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM AAA ATPase central domain protein	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
REGS1_k127_6599991_2	269799.Gmet_0938	3.531e-175	553.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,42Q5V@68525|delta/epsilon subdivisions,2WJA1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
REGS1_k127_6599991_3	243231.GSU3408	8.586e-173	546.0	COG2008@1|root,COG2008@2|Bacteria,1MWCR@1224|Proteobacteria,42NZ7@68525|delta/epsilon subdivisions,2WKSG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
REGS1_k127_6599991_4	443143.GM18_4312	1.232e-123	434.0	COG4191@1|root,COG4251@1|root,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_6599991_7	316067.Geob_2808	8.496e-49	179.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_6599991_5	448385.sce5969	5.295e-95	319.0	COG1409@1|root,COG1409@2|Bacteria,1N7CQ@1224|Proteobacteria,430CA@68525|delta/epsilon subdivisions,2WW6B@28221|Deltaproteobacteria,2YWTS@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
REGS1_k127_6599991_8	338966.Ppro_0100	9.215e-39	153.0	COG5397@1|root,COG5397@2|Bacteria,1RAQX@1224|Proteobacteria,42R41@68525|delta/epsilon subdivisions,2WN8A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
REGS1_k127_6599991_6	1121918.ARWE01000001_gene1604	3.357e-77	264.0	2BCXJ@1|root,326IF@2|Bacteria,1RHTJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6625524_3	243231.GSU0509	6.738e-58	209.0	COG3383@1|root,COG3383@2|Bacteria,1QW12@1224|Proteobacteria,43BQY@68525|delta/epsilon subdivisions,2X5UH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sfrA	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944	1.17.1.10	ko:K05299	ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_4,Fer4,Fer4_10,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
REGS1_k127_6625524_1	316067.Geob_1898	2.137e-212	678.0	COG0745@1|root,COG0745@2|Bacteria	316067.Geob_1898|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6625524_2	269799.Gmet_3021	2.75e-112	372.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
REGS1_k127_6625524_0	243231.GSU2445	0.0	1112.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42N5M@68525|delta/epsilon subdivisions,2WIIV@28221|Deltaproteobacteria,43RYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2763	Aconitase,Aconitase_C
REGS1_k127_6625524_4	580340.Tlie_1594	2.091e-44	165.0	COG2199@1|root,COG3829@1|root,COG3706@2|Bacteria,COG3829@2|Bacteria,3TAI8@508458|Synergistetes	508458|Synergistetes	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_9
REGS1_k127_6640797_7	1077972.ARGLB_085_00110	0.0001815	51.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,1W7V8@1268|Micrococcaceae	201174|Actinobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_6640797_6	443143.GM18_3843	7.233e-12	68.0	2EGUY@1|root,33AM4@2|Bacteria,1NGGE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6640797_2	443143.GM18_0177	1.959e-48	180.0	2D596@1|root,32TII@2|Bacteria,1N3RK@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6640797_1	338966.Ppro_1456	7.068e-259	805.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria,43S64@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
REGS1_k127_6640797_0	443143.GM18_2734	0.0	1034.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,43AEI@68525|delta/epsilon subdivisions,2X5UC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Alpha amylase	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
REGS1_k127_6640797_4	762903.Pedsa_0847	2.351e-29	122.0	COG4731@1|root,COG4731@2|Bacteria,4NQCK@976|Bacteroidetes,1ISS3@117747|Sphingobacteriia	976|Bacteroidetes	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
REGS1_k127_6640797_5	1232410.KI421421_gene3333	1.36e-16	81.0	COG3237@1|root,COG3237@2|Bacteria,1NGW6@1224|Proteobacteria,42XTD@68525|delta/epsilon subdivisions,2WT90@28221|Deltaproteobacteria,43VVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
REGS1_k127_6656942_1	316067.Geob_3159	7.975e-185	582.0	COG3043@1|root,COG3043@2|Bacteria,1RG8Q@1224|Proteobacteria,42S2W@68525|delta/epsilon subdivisions,2WNP8@28221|Deltaproteobacteria,43V2D@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Doubled CXXCH motif (Paired_CXXCH_1)	pccJ	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
REGS1_k127_6656942_3	316067.Geob_3158	2.528e-86	303.0	COG3391@1|root,COG3391@2|Bacteria,1NUYI@1224|Proteobacteria,42ZRG@68525|delta/epsilon subdivisions,2WV3C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_6656942_4	316067.Geob_3157	2.178e-51	187.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria	1224|Proteobacteria	NU	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
REGS1_k127_6656942_2	316067.Geob_3154	3.757e-174	560.0	COG1196@1|root,COG1196@2|Bacteria	2|Bacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR,SLH
REGS1_k127_6656942_0	269799.Gmet_0073	3.687e-257	798.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,43UFY@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
REGS1_k127_6755016_20	879212.DespoDRAFT_01664	3.279e-45	166.0	COG0614@1|root,COG0614@2|Bacteria,1N7EM@1224|Proteobacteria,42VJU@68525|delta/epsilon subdivisions,2WRA4@28221|Deltaproteobacteria,2MP0R@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
REGS1_k127_6755016_14	880072.Desac_1550	7.94e-66	229.0	COG0640@1|root,COG1669@1|root,COG0640@2|Bacteria,COG1669@2|Bacteria,1R18C@1224|Proteobacteria,43EID@68525|delta/epsilon subdivisions,2X8GT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6755016_5	443143.GM18_1770	3.547e-154	491.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
REGS1_k127_6755016_6	316067.Geob_2779	1.652e-132	426.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria,43U15@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
REGS1_k127_6755016_23	290317.Cpha266_1350	2.827e-38	148.0	COG1917@1|root,COG1917@2|Bacteria,1FE3K@1090|Chlorobi	1090|Chlorobi	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_6755016_27	146922.JOFU01000033_gene5833	1.138e-18	93.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	MA20_42425	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_6755016_25	420247.Msm_0137	2.606e-23	113.0	COG1413@1|root,arCOG02966@2157|Archaea	2157|Archaea	C	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
REGS1_k127_6755016_0	398767.Glov_2544	0.0	1125.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,43U2X@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Resolvase, RNase H domain protein fold	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
REGS1_k127_6755016_7	443143.GM18_2809	4.814e-125	406.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,42N0B@68525|delta/epsilon subdivisions,2WN21@28221|Deltaproteobacteria,43T9D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
REGS1_k127_6755016_9	316067.Geob_3300	3.678e-113	369.0	COG0670@1|root,COG0670@2|Bacteria,1MU69@1224|Proteobacteria,42MWD@68525|delta/epsilon subdivisions,2WMG9@28221|Deltaproteobacteria,43TF2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Inhibitor of apoptosis-promoting Bax1	ybhL	-	-	ko:K06890,ko:K19416	-	M00742	-	-	ko00000,ko00002,ko02000	1.A.14.2.1	-	-	Bax1-I
REGS1_k127_6755016_2	404380.Gbem_2137	2.153e-204	679.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,dCache_1
REGS1_k127_6755016_4	316067.Geob_3773	6.994e-181	573.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,42MY5@68525|delta/epsilon subdivisions,2WKST@28221|Deltaproteobacteria,43UAH@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	argE	-	3.5.1.16	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R00669,R09107	RC00064,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_6755016_12	316067.Geob_3774	1.494e-81	274.0	COG0454@1|root,COG0456@2|Bacteria,1RF31@1224|Proteobacteria,42RUB@68525|delta/epsilon subdivisions,2WN97@28221|Deltaproteobacteria,43UM1@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_6755016_21	338966.Ppro_3538	9.719e-45	166.0	COG0461@1|root,COG0461@2|Bacteria,1QXNK@1224|Proteobacteria,43E5C@68525|delta/epsilon subdivisions,2X7EZ@28221|Deltaproteobacteria,43VE5@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM type IV pilus assembly PilZ	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
REGS1_k127_6755016_22	243231.GSU1160	5.954e-41	157.0	COG3794@1|root,COG3794@2|Bacteria,1N0BX@1224|Proteobacteria	1224|Proteobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
REGS1_k127_6755016_18	338966.Ppro_1075	3.237e-54	194.0	COG0824@1|root,COG0824@2|Bacteria,1Q1JN@1224|Proteobacteria,430T1@68525|delta/epsilon subdivisions,2WVK1@28221|Deltaproteobacteria,43V7R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
REGS1_k127_6755016_13	316067.Geob_2220	1.451e-68	234.0	COG3576@1|root,COG3576@2|Bacteria,1N11C@1224|Proteobacteria,42USB@68525|delta/epsilon subdivisions,2WQDV@28221|Deltaproteobacteria,43V40@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
REGS1_k127_6755016_10	640081.Dsui_3002	3.561e-105	361.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K13040	ko02020,map02020	M00514	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9
REGS1_k127_6755016_15	338966.Ppro_0740	5.571e-65	237.0	COG2202@1|root,COG4191@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42N46@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_6755016_24	360106.CFF8240_0377	7.323e-26	121.0	COG0745@1|root,COG0745@2|Bacteria,1QUJR@1224|Proteobacteria,42NQS@68525|delta/epsilon subdivisions,2YN0F@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_6755016_29	404380.Gbem_0886	3.393e-08	57.0	2CIPY@1|root,33DN4@2|Bacteria,1NKS5@1224|Proteobacteria,42X53@68525|delta/epsilon subdivisions,2WTGT@28221|Deltaproteobacteria,43STC@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
REGS1_k127_6755016_16	443143.GM18_1040	1.624e-61	219.0	28NH4@1|root,2ZBJ2@2|Bacteria,1RADQ@1224|Proteobacteria,42UWF@68525|delta/epsilon subdivisions,2X6PD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6755016_19	316067.Geob_2778	2.247e-53	198.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria,43V7X@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Ribosomal-protein-alanine acetyltransferase	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
REGS1_k127_6755016_3	443144.GM21_1817	1.227e-182	576.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,43RZ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
REGS1_k127_6755016_11	243231.GSU1759	3.95e-84	283.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,43UEY@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
REGS1_k127_6755016_1	316067.Geob_2683	8.709e-217	681.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42MXQ@68525|delta/epsilon subdivisions,2WK2D@28221|Deltaproteobacteria,43SVC@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
REGS1_k127_6755016_8	316067.Geob_0830	5.322e-115	376.0	2C2QQ@1|root,32RAW@2|Bacteria,1NSUD@1224|Proteobacteria,42YHI@68525|delta/epsilon subdivisions,2WUH7@28221|Deltaproteobacteria,43TPF@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	omcX	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6821123_3	398767.Glov_3467	5.095e-75	258.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,43UXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_6821123_0	398767.Glov_3465	0.0	1658.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MQ0@68525|delta/epsilon subdivisions,2WISW@28221|Deltaproteobacteria,43TI4@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_6821123_4	316067.Geob_0479	7.114e-47	172.0	2C91C@1|root,30CC5@2|Bacteria,1N5NM@1224|Proteobacteria,42TXP@68525|delta/epsilon subdivisions,2WQB7@28221|Deltaproteobacteria,43VNT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
REGS1_k127_6821123_7	269799.Gmet_3122	1.097e-36	142.0	COG0607@1|root,COG0607@2|Bacteria,1PE42@1224|Proteobacteria,42V5T@68525|delta/epsilon subdivisions,2WSHC@28221|Deltaproteobacteria,43VCQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_6821123_2	316067.Geob_0607	9.705e-156	500.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
REGS1_k127_6821123_5	404380.Gbem_1155	6.406e-43	181.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K14194	ko05150,map05150	-	-	-	ko00000,ko00001	-	-	-	Cadherin,CarboxypepD_reg,DUF11,SdrD_B
REGS1_k127_6821123_8	443143.GM18_0613	5.385e-14	86.0	COG3656@1|root,COG3656@2|Bacteria	2|Bacteria	N	Periplasmic Protein	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF2271,FGE-sulfatase,Kelch_3,TIG
REGS1_k127_6821123_6	926562.Oweho_3009	1.244e-39	160.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
REGS1_k127_6821123_1	443144.GM21_0147	2.408e-161	513.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,43U1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
REGS1_k127_6852918_6	382464.ABSI01000013_gene1850	0.0003328	44.0	COG3039@1|root,COG3039@2|Bacteria,46WXW@74201|Verrucomicrobia,2IWQD@203494|Verrucomicrobiae	74201|Verrucomicrobia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
REGS1_k127_6852918_1	269799.Gmet_0789	1.377e-259	809.0	COG1012@1|root,COG1012@2|Bacteria,1R3TA@1224|Proteobacteria,42PG8@68525|delta/epsilon subdivisions,2WKCP@28221|Deltaproteobacteria,43SY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.9	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	M00308,M00633	R01058	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_6852918_5	443143.GM18_2736	7.636e-33	130.0	COG2823@1|root,COG2823@2|Bacteria,1N0SU@1224|Proteobacteria,42VD3@68525|delta/epsilon subdivisions,2WRQJ@28221|Deltaproteobacteria,43VE0@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
REGS1_k127_6852918_4	443143.GM18_2121	3.69e-43	162.0	COG0589@1|root,COG0589@2|Bacteria,1Q0M5@1224|Proteobacteria,430YY@68525|delta/epsilon subdivisions,2WVQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_6852918_0	1340493.JNIF01000004_gene40	1.255e-321	998.0	COG0021@1|root,COG0021@2|Bacteria,3Y38K@57723|Acidobacteria	57723|Acidobacteria	G	Belongs to the transketolase family	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
REGS1_k127_6852918_2	269799.Gmet_2620	1.977e-159	508.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,42MJI@68525|delta/epsilon subdivisions,2WJQP@28221|Deltaproteobacteria,43UD6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	6-phosphogluconate dehydrogenase, C-terminal domain	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2620	6PGD,NAD_binding_2
REGS1_k127_6852918_3	886293.Sinac_2020	4.259e-154	491.0	COG0364@1|root,COG0364@2|Bacteria,2IYER@203682|Planctomycetes	203682|Planctomycetes	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
REGS1_k127_6891356_5	309799.DICTH_1307	4.62e-06	48.0	COG0381@1|root,COG0381@2|Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase activity	mnaA	-	2.7.8.33,2.7.8.35,5.1.3.14	ko:K01791,ko:K02851	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420,R08856	RC00002,RC00290	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	-	iSB619.SA_RS11005	Epimerase_2
REGS1_k127_6891356_0	595460.RRSWK_06556	5.015e-68	240.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.4.1.83,6.2.1.30	ko:K00721,ko:K01912,ko:K08301	ko00360,ko00510,ko01100,ko01120,ko05111,map00360,map00510,map01100,map01120,map05111	-	R01009,R02539	RC00004,RC00005,RC00014	ko00000,ko00001,ko01000,ko01003,ko03009,ko03019	-	GT2	-	Glycos_transf_2
REGS1_k127_6891356_4	316274.Haur_3719	2.494e-17	91.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
REGS1_k127_6891356_1	316067.Geob_0934	1.214e-44	165.0	COG0346@1|root,COG0346@2|Bacteria,1NPMU@1224|Proteobacteria,42TZ4@68525|delta/epsilon subdivisions,2WQKA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_6919464_20	637905.SVI_4199	1.113e-65	241.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,1RQ86@1236|Gammaproteobacteria,2Q98I@267890|Shewanellaceae	1236|Gammaproteobacteria	U	TIGRFAM general secretion pathway protein F	gspF	GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
REGS1_k127_6919464_1	316067.Geob_0895	2.138e-261	812.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM Type II secretion system protein E	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_6919464_2	316067.Geob_0896	3.213e-253	796.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
REGS1_k127_6919464_11	316067.Geob_0897	3.258e-113	372.0	COG3031@1|root,COG3031@2|Bacteria,1PUWN@1224|Proteobacteria,42T73@68525|delta/epsilon subdivisions,2WPQU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	SMART PDZ DHR GLGF domain protein	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
REGS1_k127_6919464_17	443144.GM21_0845	2.928e-72	254.0	COG2199@1|root,COG3706@2|Bacteria,1REIE@1224|Proteobacteria	1224|Proteobacteria	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,cNMP_binding
REGS1_k127_6919464_14	243231.GSU0453	3.744e-82	281.0	COG0775@1|root,COG0775@2|Bacteria,1NDXU@1224|Proteobacteria,42TU4@68525|delta/epsilon subdivisions,2WQX3@28221|Deltaproteobacteria,43U5Q@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnB	-	3.2.2.26	ko:K11783	ko00130,ko01110,map00130,map01110	-	R08587	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_6919464_9	316067.Geob_0899	7.101e-114	375.0	COG2107@1|root,COG2107@2|Bacteria,1NYEA@1224|Proteobacteria,42MXB@68525|delta/epsilon subdivisions,2WIMS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)	mqnD	-	-	ko:K11785	ko00130,ko01110,map00130,map01110	-	R08589	RC02330	ko00000,ko00001,ko01000	-	-	-	VitK2_biosynth
REGS1_k127_6919464_5	316067.Geob_0902	7.811e-164	535.0	COG0457@1|root,COG0457@2|Bacteria,1PEPM@1224|Proteobacteria,42Y8V@68525|delta/epsilon subdivisions,2WU79@28221|Deltaproteobacteria,43TE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_8
REGS1_k127_6919464_22	316067.Geob_0903	1.845e-30	126.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspC1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
REGS1_k127_6919464_0	243231.GSU3193	0.0	1259.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,43T3K@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-3	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_6919464_12	443143.GM18_3748	1.918e-98	331.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,43UHS@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
REGS1_k127_6919464_13	316067.Geob_0927	4.107e-97	326.0	COG1352@1|root,COG1352@2|Bacteria,1NQTI@1224|Proteobacteria,42UAX@68525|delta/epsilon subdivisions,2WQ4Q@28221|Deltaproteobacteria,43UD5@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methyltransferase, chemotaxis proteins	cheR44H	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
REGS1_k127_6919464_8	443143.GM18_3728	5.621e-130	427.0	COG0840@1|root,COG0840@2|Bacteria,1RA20@1224|Proteobacteria,42QNV@68525|delta/epsilon subdivisions,2WMT1@28221|Deltaproteobacteria,43T7D@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	histidine kinase HAMP region domain protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	MCPsignal
REGS1_k127_6919464_24	768670.Calni_0993	2.416e-08	63.0	COG0835@1|root,COG0835@2|Bacteria,2GFS7@200930|Deferribacteres	200930|Deferribacteres	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_6919464_7	243231.GSU3199	1.23e-138	459.0	COG0643@1|root,COG0643@2|Bacteria,1NW7P@1224|Proteobacteria,42PGY@68525|delta/epsilon subdivisions,2WM89@28221|Deltaproteobacteria,43T85@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	difE	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
REGS1_k127_6919464_16	269799.Gmet_3208	1.654e-79	275.0	COG2834@1|root,COG2834@2|Bacteria	2|Bacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
REGS1_k127_6919464_19	316067.Geob_0922	1.449e-70	245.0	COG2834@1|root,COG2834@2|Bacteria,1PPBR@1224|Proteobacteria,42VNV@68525|delta/epsilon subdivisions,2WSI2@28221|Deltaproteobacteria,43UN6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
REGS1_k127_6919464_15	398767.Glov_3198	1.751e-80	270.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,42SVZ@68525|delta/epsilon subdivisions,2WN8K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0234 family	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
REGS1_k127_6919464_6	316067.Geob_1758	3.131e-141	455.0	COG2378@1|root,COG2378@2|Bacteria,1PE00@1224|Proteobacteria,42T67@68525|delta/epsilon subdivisions,2X5N2@28221|Deltaproteobacteria,43SWU@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
REGS1_k127_6919464_10	269799.Gmet_0487	9.893e-114	379.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NV6@68525|delta/epsilon subdivisions,2WIPB@28221|Deltaproteobacteria,43TPR@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aminotransferase class I and II	cobD	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_0487	Aminotran_1_2
REGS1_k127_6919464_3	269799.Gmet_0384	9.04e-228	711.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,42M3R@68525|delta/epsilon subdivisions,2WJGT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
REGS1_k127_6919464_21	443143.GM18_0450	4.513e-49	177.0	COG0011@1|root,COG0011@2|Bacteria,1N1NM@1224|Proteobacteria,42SC4@68525|delta/epsilon subdivisions,2WPHK@28221|Deltaproteobacteria,43VXI@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
REGS1_k127_6919464_4	269799.Gmet_0358	4.035e-191	608.0	COG0534@1|root,COG0534@2|Bacteria,1MVRV@1224|Proteobacteria,42QG6@68525|delta/epsilon subdivisions,2WNNB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	TIGRFAM MATE efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
REGS1_k127_6919464_18	243231.GSU0065	1.62e-71	246.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria,43UR2@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
REGS1_k127_6932387_2	269799.Gmet_3091	1.686e-172	546.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,42N1I@68525|delta/epsilon subdivisions,2WMZF@28221|Deltaproteobacteria,43TFV@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	2 heme-binding sites	macA	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
REGS1_k127_6932387_16	439235.Dalk_0432	2.278e-06	57.0	COG2770@1|root,COG2770@2|Bacteria,1R08R@1224|Proteobacteria,43CRE@68525|delta/epsilon subdivisions,2X7Z3@28221|Deltaproteobacteria,2MPM2@213118|Desulfobacterales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6932387_5	338969.Rfer_3142	5.355e-86	290.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,2VRA6@28216|Betaproteobacteria,4ABBS@80864|Comamonadaceae	28216|Betaproteobacteria	S	Belongs to the LOG family	yvdD_1	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
REGS1_k127_6932387_10	269799.Gmet_1790	1.15e-60	211.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,42T10@68525|delta/epsilon subdivisions,2WPNN@28221|Deltaproteobacteria,43SPG@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4
REGS1_k127_6932387_15	243231.GSU0795	1.286e-15	81.0	COG0607@1|root,COG0607@2|Bacteria	2|Bacteria	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	pspE	GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464	-	ko:K03972	-	-	-	-	ko00000	-	-	iE2348C_1286.E2348C_1500,iECABU_c1320.ECABU_c15910,iSDY_1059.SDY_1936,ic_1306.c1779	Rhodanese
REGS1_k127_6932387_7	398767.Glov_1303	9.665e-81	275.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42MCG@68525|delta/epsilon subdivisions,2WKEQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_6932387_6	523845.AQXV01000026_gene1469	1.495e-84	309.0	arCOG02545@1|root,arCOG02545@2157|Archaea	2157|Archaea	S	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,PKD
REGS1_k127_6932387_12	357808.RoseRS_1673	1.836e-33	150.0	COG1470@1|root,COG1716@1|root,COG1470@2|Bacteria,COG1716@2|Bacteria,2G8JT@200795|Chloroflexi	200795|Chloroflexi	T	FHA domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
REGS1_k127_6932387_4	269799.Gmet_0235	6.349e-132	426.0	COG2996@1|root,COG2996@2|Bacteria,1MXC3@1224|Proteobacteria,42P2A@68525|delta/epsilon subdivisions,2WKAS@28221|Deltaproteobacteria,43SFB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	S1 domain	-	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1_2
REGS1_k127_6932387_1	1232410.KI421421_gene3465	1.975e-281	873.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,43S4H@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
REGS1_k127_6932387_9	316067.Geob_2236	5.874e-67	232.0	COG2191@1|root,COG2191@2|Bacteria,1RBNI@1224|Proteobacteria,42QZP@68525|delta/epsilon subdivisions,2WMY0@28221|Deltaproteobacteria,43VP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	FmdE, Molybdenum formylmethanofuran dehydrogenase operon	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
REGS1_k127_6932387_8	335543.Sfum_1335	1.519e-75	265.0	2CIBN@1|root,2Z8JT@2|Bacteria,1QGIJ@1224|Proteobacteria,42S2V@68525|delta/epsilon subdivisions,2WNZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6932387_14	404380.Gbem_1323	1.122e-23	111.0	COG0810@1|root,COG0810@2|Bacteria,1NI45@1224|Proteobacteria,42VVY@68525|delta/epsilon subdivisions,2WRZC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2
REGS1_k127_6932387_0	243231.GSU2191	3.259e-295	913.0	COG2414@1|root,COG2414@2|Bacteria,1MWBB@1224|Proteobacteria,42NR7@68525|delta/epsilon subdivisions,2WK49@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Aldehyde ferredoxin oxidoreductase	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
REGS1_k127_6932387_3	316067.Geob_1874	2.248e-141	456.0	COG0836@1|root,COG0836@2|Bacteria,1MV39@1224|Proteobacteria,42MDP@68525|delta/epsilon subdivisions,2WJEN@28221|Deltaproteobacteria,43SV5@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	mannose-6-phosphate isomerase	manAC	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
REGS1_k127_6932494_9	1288826.MSNKSG1_00848	9.988e-30	124.0	2ACDM@1|root,311Z0@2|Bacteria,1RFMN@1224|Proteobacteria,1S3S3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6932494_2	338963.Pcar_0672	2.335e-87	298.0	COG2208@1|root,COG2208@2|Bacteria,1N049@1224|Proteobacteria,42UJI@68525|delta/epsilon subdivisions,2WQ48@28221|Deltaproteobacteria,43SQ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
REGS1_k127_6932494_0	443143.GM18_0084	0.0	1168.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,42N4Y@68525|delta/epsilon subdivisions,2WKGT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	DinB superfamily	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	DinB_2,FGE-sulfatase,Methyltransf_31
REGS1_k127_6932494_4	398767.Glov_3002	2.196e-68	236.0	COG0778@1|root,COG0778@2|Bacteria,1REJI@1224|Proteobacteria,42RKQ@68525|delta/epsilon subdivisions,2WNPF@28221|Deltaproteobacteria,43UVH@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_6932494_8	977880.RALTA_A1510	9.979e-37	141.0	COG0662@1|root,COG0662@2|Bacteria,1QUHG@1224|Proteobacteria,2WGPE@28216|Betaproteobacteria,1KG9F@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Cupin domain	-	-	-	ko:K11312	-	-	-	-	ko00000	-	-	-	Cupin_2
REGS1_k127_6932494_5	404380.Gbem_0519	1.857e-58	211.0	COG0727@1|root,COG0727@2|Bacteria,1NV2K@1224|Proteobacteria,42ZNY@68525|delta/epsilon subdivisions,2WUS7@28221|Deltaproteobacteria,43URP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
REGS1_k127_6932494_1	316067.Geob_1753	8.153e-153	492.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WQ50@28221|Deltaproteobacteria,43TT7@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	cls-1	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3078	PLDc_2
REGS1_k127_6932494_7	269799.Gmet_3080	6.455e-37	139.0	COG0694@1|root,COG0694@2|Bacteria,1MVQ1@1224|Proteobacteria,42V85@68525|delta/epsilon subdivisions,2WR93@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM nitrogen-fixing NifU domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Nfu_N,NifU
REGS1_k127_6932494_6	269799.Gmet_3083	5.326e-55	201.0	COG0546@1|root,COG1633@1|root,COG0546@2|Bacteria,COG1633@2|Bacteria,1NJ35@1224|Proteobacteria,42WXC@68525|delta/epsilon subdivisions,2WVH2@28221|Deltaproteobacteria,43UVF@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM Haloacid dehalogenase domain protein hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
REGS1_k127_6932494_3	269799.Gmet_3084	1.647e-83	282.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,42VQA@68525|delta/epsilon subdivisions,2WUV1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
REGS1_k127_6965761_10	316067.Geob_0754	1.144e-156	503.0	COG1145@1|root,COG2006@1|root,COG1145@2|Bacteria,COG2006@2|Bacteria,1RABP@1224|Proteobacteria,42QQA@68525|delta/epsilon subdivisions,2WMRX@28221|Deltaproteobacteria,43U50@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
REGS1_k127_6965761_18	269799.Gmet_2807	1.183e-64	224.0	COG1661@1|root,COG1661@2|Bacteria,1RIUJ@1224|Proteobacteria,42SC0@68525|delta/epsilon subdivisions,2WPPG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF296
REGS1_k127_6965761_12	269799.Gmet_3042	5.857e-125	407.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,43U9P@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_6965761_21	398767.Glov_1268	2.924e-51	188.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_6965761_25	398767.Glov_1269	6.478e-41	164.0	COG3170@1|root,COG3170@2|Bacteria,1NHGQ@1224|Proteobacteria,42X64@68525|delta/epsilon subdivisions,2WSMQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DUF2275,zf-HC2
REGS1_k127_6965761_16	398767.Glov_1270	1.521e-98	331.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,4330X@68525|delta/epsilon subdivisions,2WXN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6965761_23	269799.Gmet_2533	2.713e-47	171.0	COG3657@1|root,COG3657@2|Bacteria,1N74C@1224|Proteobacteria,42V2I@68525|delta/epsilon subdivisions,2WRI9@28221|Deltaproteobacteria,43VGH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TIGRFAM Addiction module killer protein	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
REGS1_k127_6965761_22	404380.Gbem_2965	2.043e-49	177.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,42STB@68525|delta/epsilon subdivisions,2WP7C@28221|Deltaproteobacteria,43VS4@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	TIGRFAM addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_6965761_27	1128912.GMES_0199	2.961e-29	126.0	2AAHJ@1|root,349GG@2|Bacteria,1P253@1224|Proteobacteria,1SRXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6965761_9	269799.Gmet_0117	7.117e-177	559.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,42M6R@68525|delta/epsilon subdivisions,2WJDQ@28221|Deltaproteobacteria,43U45@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	iAF987.Gmet_0117	HypD
REGS1_k127_6965761_28	269799.Gmet_0118	4.783e-28	114.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,42X24@68525|delta/epsilon subdivisions,2WSTX@28221|Deltaproteobacteria,43STB@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
REGS1_k127_6965761_3	269799.Gmet_0119	1.105e-287	903.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,42M3G@68525|delta/epsilon subdivisions,2WJ51@28221|Deltaproteobacteria,43S2B@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	iAF987.Gmet_0119	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
REGS1_k127_6965761_7	269799.Gmet_0122	1.176e-208	659.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,42N30@68525|delta/epsilon subdivisions,2WJSW@28221|Deltaproteobacteria,43TCB@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	iAF987.Gmet_0122	Fer4_9,PK,PK_C
REGS1_k127_6965761_26	338966.Ppro_3605	9.14e-35	136.0	2EQXI@1|root,33IH9@2|Bacteria,1NK2X@1224|Proteobacteria,42X7E@68525|delta/epsilon subdivisions,2WSQE@28221|Deltaproteobacteria,43VA4@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6965761_17	316067.Geob_3204	6.701e-98	327.0	COG1752@1|root,COG1752@2|Bacteria,1R4TX@1224|Proteobacteria	1224|Proteobacteria	I	Esterase of the alpha-beta hydrolase superfamily	rssA	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
REGS1_k127_6965761_11	269799.Gmet_3256	4.465e-151	492.0	COG5386@1|root,COG5386@2|Bacteria,1QWPV@1224|Proteobacteria,43BUN@68525|delta/epsilon subdivisions,2X75R@28221|Deltaproteobacteria,43UJG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
REGS1_k127_6965761_14	443143.GM18_3798	6.453e-108	366.0	2C4SP@1|root,32V35@2|Bacteria,1N1U0@1224|Proteobacteria,42TP1@68525|delta/epsilon subdivisions,2WQS0@28221|Deltaproteobacteria,43U3U@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6965761_19	338966.Ppro_0522	2.259e-62	216.0	COG0346@1|root,COG0346@2|Bacteria,1RCYU@1224|Proteobacteria,42URG@68525|delta/epsilon subdivisions,2WNDG@28221|Deltaproteobacteria,43URU@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Glyoxalase-like domain	mceE	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
REGS1_k127_6965761_2	316067.Geob_0840	3.3e-316	972.0	COG1884@1|root,COG1884@2|Bacteria,1MUXX@1224|Proteobacteria,42P03@68525|delta/epsilon subdivisions,2WIPY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01848	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
REGS1_k127_6965761_13	269799.Gmet_3250	2.952e-114	372.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iSB619.SA_RS02535	Thymidylate_kin
REGS1_k127_6965761_0	269799.Gmet_3249	0.0	1749.0	COG0439@1|root,COG0511@1|root,COG0439@2|Bacteria,COG0511@2|Bacteria,1N71M@1224|Proteobacteria,42YTA@68525|delta/epsilon subdivisions,2WU1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM biotin lipoyl attachment domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
REGS1_k127_6965761_1	243231.GSU3299	0.0	1069.0	COG4799@1|root,COG4799@2|Bacteria,1MVAX@1224|Proteobacteria,43AEE@68525|delta/epsilon subdivisions,2WIRF@28221|Deltaproteobacteria,43TAX@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
REGS1_k127_6965761_15	269799.Gmet_3247	6.933e-106	345.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1RG01@1224|Proteobacteria,42S3T@68525|delta/epsilon subdivisions,2WNTQ@28221|Deltaproteobacteria,43SGR@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
REGS1_k127_6965761_5	269799.Gmet_3246	7.782e-255	788.0	COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2WJ1F@28221|Deltaproteobacteria,43TPH@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	larF	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_8
REGS1_k127_6965761_4	269799.Gmet_3245	1.26e-275	850.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM FAD linked oxidase domain protein	larD	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3245	FAD-oxidase_C,FAD_binding_4
REGS1_k127_6965761_8	269799.Gmet_3244	1.804e-185	591.0	COG3875@1|root,COG3875@2|Bacteria,1RFFK@1224|Proteobacteria,43B2T@68525|delta/epsilon subdivisions,2X6GN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2088)	larA	-	-	-	-	-	-	-	-	-	-	-	DUF2088
REGS1_k127_6965761_20	398767.Glov_2591	1.23e-55	196.0	COG2033@1|root,COG2033@2|Bacteria,1RHE0@1224|Proteobacteria,42SB9@68525|delta/epsilon subdivisions,2WP2D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Desulfoferrodoxin ferrous iron-binding	dfx	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
REGS1_k127_6965761_6	269799.Gmet_3243	1.933e-212	665.0	COG0426@1|root,COG0426@2|Bacteria,1R4UD@1224|Proteobacteria,43AF5@68525|delta/epsilon subdivisions,2X5UW@28221|Deltaproteobacteria,43W35@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Flavodoxin	roo	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Lactamase_B,Lactamase_B_2
REGS1_k127_6965761_29	269799.Gmet_3241	4.296e-14	71.0	COG1592@1|root,COG1592@2|Bacteria	2|Bacteria	C	Rubrerythrin	hrb	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_3241	Flavin_Reduct,Rubrerythrin
REGS1_k127_6965761_24	243231.GSU3292	2.195e-44	166.0	COG0735@1|root,COG0735@2|Bacteria,1N0HW@1224|Proteobacteria,42TU6@68525|delta/epsilon subdivisions,2WPZ1@28221|Deltaproteobacteria,43VCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
REGS1_k127_6965761_30	269799.Gmet_3239	1.958e-12	66.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,42N1H@68525|delta/epsilon subdivisions,2WJ0R@28221|Deltaproteobacteria,43T0F@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
REGS1_k127_7068532_5	316067.Geob_2165	2.167e-86	300.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,43UH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
REGS1_k127_7068532_6	316067.Geob_2164	1.1e-81	282.0	COG0745@1|root,COG0745@2|Bacteria,1NV0N@1224|Proteobacteria,42ZH3@68525|delta/epsilon subdivisions,2WUW0@28221|Deltaproteobacteria,43UQG@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,zinc_ribbon_4
REGS1_k127_7068532_8	243231.GSU2218	5.577e-55	196.0	COG0835@1|root,COG0835@2|Bacteria,1N6GU@1224|Proteobacteria,42TH8@68525|delta/epsilon subdivisions,2WQV4@28221|Deltaproteobacteria,43VA6@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	cheW40H-2	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_7068532_10	269799.Gmet_2308	9.58e-44	164.0	COG0745@1|root,COG0745@2|Bacteria,1RHCU@1224|Proteobacteria,42ZZE@68525|delta/epsilon subdivisions,2WV71@28221|Deltaproteobacteria,43UZ2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	cheY40H-2	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_7068532_7	316067.Geob_2161	2.44e-58	215.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5TT@28221|Deltaproteobacteria,43V4F@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	PFAM CheW domain protein	cheW40H-1	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_7068532_4	316067.Geob_2160	2.444e-113	371.0	COG3267@1|root,COG3267@2|Bacteria,1REY9@1224|Proteobacteria,42RJB@68525|delta/epsilon subdivisions,2WN99@28221|Deltaproteobacteria,43TEB@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Pfam:Arch_ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
REGS1_k127_7068532_0	316067.Geob_2159	4.514e-280	876.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,43S5Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase homodimeric	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
REGS1_k127_7068532_9	316067.Geob_2158	6.612e-53	192.0	COG0745@1|root,COG0745@2|Bacteria,1N1TA@1224|Proteobacteria,42V03@68525|delta/epsilon subdivisions,2WPZR@28221|Deltaproteobacteria,43V4S@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM response regulator receiver	cheY40H-1	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
REGS1_k127_7068532_2	316067.Geob_2157	6.229e-181	582.0	COG0745@1|root,COG0745@2|Bacteria,1N9YT@1224|Proteobacteria,42W15@68525|delta/epsilon subdivisions,2WS2V@28221|Deltaproteobacteria,43T56@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	regulator, PATAN and FRGAF domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
REGS1_k127_7068532_1	269799.Gmet_2314	9.314e-216	679.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,43U5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
REGS1_k127_7068532_3	269799.Gmet_2315	1.76e-126	411.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,43TV2@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
REGS1_k127_7089991_15	33035.JPJF01000076_gene5060	3.071e-09	65.0	COG0500@1|root,COG0500@2|Bacteria,1UI1D@1239|Firmicutes,25EAD@186801|Clostridia,3Y0F8@572511|Blautia	186801|Clostridia	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,NUDIX
REGS1_k127_7089991_14	1227487.C474_01896	4.982e-10	69.0	arCOG01792@1|root,arCOG01792@2157|Archaea,2XW2T@28890|Euryarchaeota,23U9Q@183963|Halobacteria	183963|Halobacteria	Q	COG0500 SAM-dependent methyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_7089991_1	269799.Gmet_3485	7.709e-193	616.0	COG1376@1|root,COG1376@2|Bacteria,1MVYT@1224|Proteobacteria,42ZCU@68525|delta/epsilon subdivisions,2WTVT@28221|Deltaproteobacteria,43U8N@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	ko:K16291	-	-	-	-	ko00000,ko01002,ko01011	-	-	-	LysM,SPOR,YkuD
REGS1_k127_7089991_12	338966.Ppro_0572	2.108e-28	118.0	2EFUG@1|root,339KM@2|Bacteria,1NGQQ@1224|Proteobacteria,430N8@68525|delta/epsilon subdivisions,2WVUR@28221|Deltaproteobacteria,43VA8@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Alanine-zipper, major outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	Alanine_zipper
REGS1_k127_7089991_5	269799.Gmet_3487	1.18e-128	420.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,42TV7@68525|delta/epsilon subdivisions,2WRW0@28221|Deltaproteobacteria,43TY1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6,YkuD
REGS1_k127_7089991_17	269799.Gmet_0241	0.0007442	43.0	2DBPG@1|root,2ZA96@2|Bacteria,1QVNF@1224|Proteobacteria,42VXK@68525|delta/epsilon subdivisions,2WRZ5@28221|Deltaproteobacteria,43UW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4382
REGS1_k127_7089991_10	1232410.KI421421_gene3902	1.048e-42	160.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,43V7Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7089991_6	243231.GSU1060	2.733e-122	398.0	2EZKF@1|root,33SRH@2|Bacteria,1NRXB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7089991_11	316067.Geob_2397	1.185e-34	140.0	2BX4M@1|root,2ZKVT@2|Bacteria,1P6KE@1224|Proteobacteria,4331W@68525|delta/epsilon subdivisions,2WYFI@28221|Deltaproteobacteria,43VNM@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7089991_7	1232410.KI421416_gene2665	5.556e-121	403.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42T7G@68525|delta/epsilon subdivisions,2X75V@28221|Deltaproteobacteria,43UEH@69541|Desulfuromonadales	28221|Deltaproteobacteria	KT	Single cache domain 3	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HD,HD_5,sCache_3_2
REGS1_k127_7089991_16	338966.Ppro_2849	7.511e-06	51.0	COG4447@1|root,COG4447@2|Bacteria,1PFCA@1224|Proteobacteria,42WUH@68525|delta/epsilon subdivisions,2WT3I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	fn3
REGS1_k127_7089991_8	404380.Gbem_0784	6.227e-95	313.0	COG0655@1|root,COG0655@2|Bacteria,1PFC3@1224|Proteobacteria,434BZ@68525|delta/epsilon subdivisions,2X1YF@28221|Deltaproteobacteria,43VQT@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_7089991_0	316067.Geob_0080	4.833e-209	655.0	COG1064@1|root,COG1064@2|Bacteria,1MUTT@1224|Proteobacteria,42MY6@68525|delta/epsilon subdivisions,2WME2@28221|Deltaproteobacteria,43VHY@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Alcohol dehydrogenase GroES-like domain	mtd	-	-	ko:K13979	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_7089991_2	338966.Ppro_0110	4.4e-186	584.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,43TBX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_7089991_3	338963.Pcar_1091	5.35e-149	477.0	COG2207@1|root,COG2207@2|Bacteria,1MUEM@1224|Proteobacteria,42PBT@68525|delta/epsilon subdivisions,2WMAY@28221|Deltaproteobacteria,43TIB@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_N,HTH_18
REGS1_k127_7089991_9	243231.GSU0767	5.026e-68	239.0	COG3637@1|root,COG3637@2|Bacteria,1NGKR@1224|Proteobacteria,42XMD@68525|delta/epsilon subdivisions,2WSIW@28221|Deltaproteobacteria,43UMH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
REGS1_k127_7089991_4	243231.GSU0126	5.07e-144	463.0	COG0348@1|root,COG0348@2|Bacteria,1MY5M@1224|Proteobacteria,42QNC@68525|delta/epsilon subdivisions,2WMUV@28221|Deltaproteobacteria,43UI8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	yccM-1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_5
REGS1_k127_7090069_5	316067.Geob_3707	3.785e-18	89.0	28QKF@1|root,2ZD28@2|Bacteria,1P6Y3@1224|Proteobacteria,432ID@68525|delta/epsilon subdivisions,2WYCE@28221|Deltaproteobacteria,43VPU@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7090069_1	269799.Gmet_3272	3.751e-155	495.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43U3B@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-1	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_7090069_3	243231.GSU0291	2.27e-80	280.0	COG1352@1|root,COG1352@2|Bacteria,1NV9H@1224|Proteobacteria,42ZTE@68525|delta/epsilon subdivisions,2WUVS@28221|Deltaproteobacteria,43URJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	-	-	-	-	-	-	-	-	-	-	-	-	CheR
REGS1_k127_7090069_2	316067.Geob_1029	1.516e-90	310.0	COG3170@1|root,COG3170@2|Bacteria,1NQKD@1224|Proteobacteria,42Z93@68525|delta/epsilon subdivisions,2WTX7@28221|Deltaproteobacteria,43U5V@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7090069_4	316067.Geob_1920	5.386e-47	179.0	COG3017@1|root,COG3017@2|Bacteria,1NXUH@1224|Proteobacteria,430GS@68525|delta/epsilon subdivisions,2WW2S@28221|Deltaproteobacteria,43V9S@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein LolB	-	-	-	-	-	-	-	-	-	-	-	-	LolB
REGS1_k127_7090069_0	269799.Gmet_2918	0.0	1282.0	COG0366@1|root,COG0366@2|Bacteria,1PDXT@1224|Proteobacteria,42MZ1@68525|delta/epsilon subdivisions,2WMHA@28221|Deltaproteobacteria,43U2K@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM alpha amylase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
REGS1_k127_71845_8	643562.Daes_2669	2.247e-34	133.0	COG1960@1|root,COG1960@2|Bacteria,1PZ0R@1224|Proteobacteria,43E91@68525|delta/epsilon subdivisions,2X018@28221|Deltaproteobacteria,2M9QP@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
REGS1_k127_71845_1	316067.Geob_1746	1.017e-230	720.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,43SXC@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
REGS1_k127_71845_3	243231.GSU2556	1.107e-181	575.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2WJZR@28221|Deltaproteobacteria,43TIN@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	PFAM peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
REGS1_k127_71845_6	443144.GM21_3414	4.159e-74	261.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria,43UMV@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
REGS1_k127_71845_7	269799.Gmet_2741	4.02e-60	219.0	COG1597@1|root,COG1597@2|Bacteria,1MY37@1224|Proteobacteria,42RSB@68525|delta/epsilon subdivisions,2WRW1@28221|Deltaproteobacteria,43UT6@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	PFAM diacylglycerol kinase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
REGS1_k127_71845_9	680646.RMDY18_02610	4.044e-07	61.0	2FA3W@1|root,342CR@2|Bacteria,2H5SD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_71845_4	443144.GM21_3721	3.631e-168	541.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,42ZM6@68525|delta/epsilon subdivisions,2WV3N@28221|Deltaproteobacteria,43S9F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Member of a two-component regulatory system	-	-	2.7.13.3	ko:K07644	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HATPase_c,HisKA
REGS1_k127_71845_0	443143.GM18_4081	8.697e-318	982.0	COG1368@1|root,COG1368@2|Bacteria,1MVCM@1224|Proteobacteria,42P62@68525|delta/epsilon subdivisions,2WKBP@28221|Deltaproteobacteria,43V54@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,Sulfatase
REGS1_k127_71845_5	316067.Geob_1553	6.332e-164	531.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,43TBY@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 39	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
REGS1_k127_71845_2	404380.Gbem_2982	4.666e-220	687.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_7259363_10	156889.Mmc1_1148	2.449e-35	137.0	COG2199@1|root,COG4564@1|root,COG3706@2|Bacteria,COG4564@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	CZB,GGDEF
REGS1_k127_7259363_8	589865.DaAHT2_1363	2.436e-50	182.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,42T9C@68525|delta/epsilon subdivisions,2WP3Z@28221|Deltaproteobacteria,2MKTX@213118|Desulfobacterales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_7259363_6	243231.GSU2567	1.145e-81	289.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,HAMP,HATPase_c,HisKA,MASE3,PAS_3,PAS_4,PAS_9,dCache_1
REGS1_k127_7259363_5	1121403.AUCV01000003_gene1737	8.771e-86	295.0	COG3221@1|root,COG3221@2|Bacteria,1QJET@1224|Proteobacteria,42TZD@68525|delta/epsilon subdivisions,2WQIE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Phosphonate ABC transporter, periplasmic	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_7259363_2	269799.Gmet_0344	1.4e-164	526.0	COG3864@1|root,COG3864@2|Bacteria,1MY13@1224|Proteobacteria,42QJ2@68525|delta/epsilon subdivisions,2WM78@28221|Deltaproteobacteria,43VD6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
REGS1_k127_7259363_1	316067.Geob_2990	9.456e-171	560.0	COG1287@1|root,COG1287@2|Bacteria,1NYIS@1224|Proteobacteria,430I0@68525|delta/epsilon subdivisions,2WW3Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	oligosaccharyl transferase activity	-	-	2.4.99.18	ko:K07151	ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141	M00072	R04216,R05976	RC00005,RC00482	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT66	-	STT3
REGS1_k127_7259363_3	316067.Geob_1328	4.234e-159	507.0	COG0714@1|root,COG0714@2|Bacteria,1PHW4@1224|Proteobacteria,42VWM@68525|delta/epsilon subdivisions,2X5MC@28221|Deltaproteobacteria,43VQ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7259363_0	443144.GM21_0292	5.436e-172	548.0	COG3550@1|root,COG3550@2|Bacteria,1MVAB@1224|Proteobacteria,42PTQ@68525|delta/epsilon subdivisions,2WJBP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	HipA N-terminal domain protein	hipA	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
REGS1_k127_7259363_11	443144.GM21_0291	1.19e-34	135.0	COG1396@1|root,COG1396@2|Bacteria,1NGFD@1224|Proteobacteria	1224|Proteobacteria	K	TRANSCRIPTIONal	-	-	-	ko:K15773	-	-	-	-	ko00000,ko02048,ko03000	-	-	-	HTH_19,HTH_3,HTH_31
REGS1_k127_7259363_9	243231.GSU3461	3.984e-50	181.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42WIA@68525|delta/epsilon subdivisions,2WS9S@28221|Deltaproteobacteria,43VW7@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM thioesterase superfamily protein	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
REGS1_k127_7259363_4	443144.GM21_0849	1.333e-105	348.0	COG1215@1|root,COG2344@1|root,COG1215@2|Bacteria,COG2344@2|Bacteria,1R988@1224|Proteobacteria,42QKI@68525|delta/epsilon subdivisions,2WM6J@28221|Deltaproteobacteria,43S6T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_7318595_14	639283.Snov_3765	4.396e-95	317.0	COG1215@1|root,COG1215@2|Bacteria,1QU2F@1224|Proteobacteria,2U0P8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_7318595_28	211114.JOEF01000054_gene4697	5.833e-08	64.0	COG0859@1|root,COG0859@2|Bacteria,2GMWP@201174|Actinobacteria,4E1C2@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
REGS1_k127_7318595_15	103690.17134258	1.594e-93	329.0	COG1807@1|root,COG1807@2|Bacteria,1G0W2@1117|Cyanobacteria	1117|Cyanobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_7318595_16	1380763.BG53_11530	9.822e-89	302.0	2DBCR@1|root,2Z8FA@2|Bacteria,1V8ZT@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7318595_1	1232410.KI421412_gene259	1.165e-146	477.0	COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,42MH6@68525|delta/epsilon subdivisions,2WKH9@28221|Deltaproteobacteria,43TYU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
REGS1_k127_7318595_17	443144.GM21_2464	4.952e-86	299.0	COG5653@1|root,COG5653@2|Bacteria,1NCB6@1224|Proteobacteria	1224|Proteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
REGS1_k127_7318595_22	1232410.KI421412_gene277	6.49e-55	201.0	COG2890@1|root,COG2890@2|Bacteria,1QXMU@1224|Proteobacteria	1224|Proteobacteria	J	protein-(glutamine-N5) methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DOT1
REGS1_k127_7318595_8	1232410.KI421412_gene273	1.474e-108	360.0	COG0726@1|root,COG0726@2|Bacteria,1MVKH@1224|Proteobacteria,42VRI@68525|delta/epsilon subdivisions,2WRUV@28221|Deltaproteobacteria,43VFC@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_7318595_3	1232410.KI421412_gene272	7.765e-143	465.0	COG0438@1|root,COG0438@2|Bacteria,1MWYH@1224|Proteobacteria,42Q22@68525|delta/epsilon subdivisions,2WK61@28221|Deltaproteobacteria,43TI1@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_7318595_25	330214.NIDE2876	4.979e-21	105.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,Lipase_GDSL_2
REGS1_k127_7318595_27	870187.Thini_3470	2.337e-10	62.0	2EGPU@1|root,33AFZ@2|Bacteria,1NH69@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7318595_20	1232410.KI421412_gene252	2.861e-65	235.0	COG1215@1|root,COG1215@2|Bacteria,1QW0Y@1224|Proteobacteria,43BQU@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_7318595_10	404380.Gbem_0853	4.948e-108	362.0	COG0438@1|root,COG0438@2|Bacteria,1PEGM@1224|Proteobacteria,43AEB@68525|delta/epsilon subdivisions,2X5U6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_7318595_12	82654.Pse7367_1948	1.04e-104	349.0	28K7U@1|root,2Z9VT@2|Bacteria,1G5J6@1117|Cyanobacteria,1HG8J@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7318595_13	1232410.KI421412_gene252	5.242e-96	324.0	COG1215@1|root,COG1215@2|Bacteria,1QW0Y@1224|Proteobacteria,43BQU@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_7318595_18	641491.DND132_1483	2.2e-75	272.0	COG0438@1|root,COG0438@2|Bacteria,1N1RZ@1224|Proteobacteria,42UHY@68525|delta/epsilon subdivisions,2WQD7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_7318595_6	335543.Sfum_1870	8.394e-117	395.0	COG0457@1|root,COG1807@1|root,COG0457@2|Bacteria,COG1807@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MRCI@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
REGS1_k127_7318595_4	443143.GM18_0604	2.871e-134	441.0	COG4393@1|root,COG4393@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2318
REGS1_k127_7318595_5	443144.GM21_3548	1.724e-126	406.0	COG1136@1|root,COG1136@2|Bacteria,1Q3QX@1224|Proteobacteria,42NVX@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	abc transporter atp-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_7318595_23	404380.Gbem_0838	3.861e-30	128.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
REGS1_k127_7318595_24	292459.STH855	6e-26	121.0	COG0577@1|root,COG0577@2|Bacteria,1UYZ9@1239|Firmicutes,2484S@186801|Clostridia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_7318595_2	443143.GM18_0602	3.402e-145	470.0	COG0577@1|root,COG0577@2|Bacteria,1R6DP@1224|Proteobacteria,42PWX@68525|delta/epsilon subdivisions,2WJSB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_7318595_0	316067.Geob_0061	1.517e-187	593.0	COG0577@1|root,COG0577@2|Bacteria,1PU2M@1224|Proteobacteria,43AD5@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_7318595_11	316067.Geob_0055	2.411e-106	355.0	COG5263@1|root,COG5263@2|Bacteria,1RJ7C@1224|Proteobacteria,42UPW@68525|delta/epsilon subdivisions,2WSFE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	WG containing repeat	-	-	-	-	-	-	-	-	-	-	-	-	WG_beta_rep
REGS1_k127_7318595_9	443144.GM21_3557	3.684e-108	366.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	resB	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
REGS1_k127_7318595_19	443143.GM18_0596	1.256e-73	252.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_7361112_6	269799.Gmet_3217	1.039e-22	98.0	COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,43VPN@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_7361112_0	269799.Gmet_3219	0.0	1091.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,43U9W@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
REGS1_k127_7361112_7	107635.AZUO01000001_gene1250	2.845e-17	93.0	COG2020@1|root,COG2020@2|Bacteria,1RBFX@1224|Proteobacteria,2U68D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
REGS1_k127_7361112_4	497964.CfE428DRAFT_5414	2.404e-121	428.0	COG0457@1|root,COG0457@2|Bacteria	497964.CfE428DRAFT_5414|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7361112_1	316067.Geob_2051	1.618e-220	700.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,42TQ5@68525|delta/epsilon subdivisions,2WQ0T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
REGS1_k127_7361112_5	316067.Geob_3206	5.479e-50	190.0	COG2984@1|root,COG2984@2|Bacteria	2|Bacteria	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
REGS1_k127_7361112_2	316067.Geob_3207	7.137e-153	503.0	COG1629@1|root,COG4771@2|Bacteria,1RA71@1224|Proteobacteria,43CDT@68525|delta/epsilon subdivisions,2X7PR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14.3	-	-	Plug
REGS1_k127_7361112_3	443143.GM18_3134	2.286e-146	486.0	COG1994@1|root,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,42WVB@68525|delta/epsilon subdivisions,2WT41@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7379281_6	243231.GSU1555	1.495e-27	130.0	COG3829@1|root,COG4191@1|root,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	5TM-5TMR_LYT,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_7379281_3	269799.Gmet_0666	1.229e-117	402.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria,43C58@68525|delta/epsilon subdivisions,2X7FM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sensor histidine kinase, PAS, PAS, PAS and PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9
REGS1_k127_7379281_5	269799.Gmet_3414	1.351e-30	124.0	COG0784@1|root,COG0784@2|Bacteria	2|Bacteria	T	Response regulator, receiver	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
REGS1_k127_7379281_0	316067.Geob_3443	0.0	1047.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2WK62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
REGS1_k127_7379281_2	243231.GSU2388	9.756e-118	407.0	COG4251@1|root,COG5002@1|root,COG4251@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,dCache_1
REGS1_k127_7379281_1	156889.Mmc1_1122	3.262e-168	542.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TRWB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
REGS1_k127_7379281_4	269799.Gmet_2496	6.982e-57	201.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,42QTS@68525|delta/epsilon subdivisions,2WN02@28221|Deltaproteobacteria,43TCX@69541|Desulfuromonadales	28221|Deltaproteobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2496	GATase
REGS1_k127_7383536_3	404380.Gbem_2327	6.372e-23	102.0	COG0727@1|root,COG0727@2|Bacteria,1REPM@1224|Proteobacteria,42RPZ@68525|delta/epsilon subdivisions,2WNSE@28221|Deltaproteobacteria,43UMY@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
REGS1_k127_7383536_5	243231.GSU0891	5.579e-07	63.0	COG1361@1|root,COG1404@1|root,COG5549@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG5549@2|Bacteria,1RC5K@1224|Proteobacteria,42U2I@68525|delta/epsilon subdivisions,2WQAT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
REGS1_k127_7383536_4	1122221.JHVI01000002_gene787	3.132e-13	83.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
REGS1_k127_7383536_2	192952.MM_3203	6.638e-98	347.0	COG4870@1|root,arCOG03991@1|root,arCOG03607@2157|Archaea,arCOG03991@2157|Archaea,2XWQ1@28890|Euryarchaeota	28890|Euryarchaeota	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_C1
REGS1_k127_7383536_1	398767.Glov_2703	8.427e-107	347.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WPAX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
REGS1_k127_7383536_0	316067.Geob_2890	4.183e-112	363.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,42MDB@68525|delta/epsilon subdivisions,2WITV@28221|Deltaproteobacteria,43UES@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
REGS1_k127_7391878_0	316067.Geob_3132	9.575e-146	510.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_7391878_2	1340493.JNIF01000003_gene1479	9.912e-56	205.0	COG2227@1|root,COG2227@2|Bacteria,3Y8MU@57723|Acidobacteria	57723|Acidobacteria	H	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_7391878_1	1337936.IJ00_19120	5.347e-82	282.0	COG0697@1|root,COG0697@2|Bacteria,1G0QG@1117|Cyanobacteria,1HKH8@1161|Nostocales	1117|Cyanobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_7391878_3	1157490.EL26_07605	1.296e-47	188.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli,27801@186823|Alicyclobacillaceae	91061|Bacilli	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_7402859_2	472759.Nhal_1631	2.508e-30	135.0	COG1618@1|root,COG1618@2|Bacteria,1R0HW@1224|Proteobacteria	1224|Proteobacteria	F	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
REGS1_k127_7402859_3	1454004.AW11_01234	1.959e-27	126.0	2E53J@1|root,32ZWN@2|Bacteria,1QYNA@1224|Proteobacteria	1224|Proteobacteria	S	Uncharacterised nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_5
REGS1_k127_7402859_0	404380.Gbem_2752	2.016e-106	351.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2WMWK@28221|Deltaproteobacteria,43T14@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
REGS1_k127_7402859_1	243231.GSU1916	2.305e-83	284.0	COG4589@1|root,COG4589@2|Bacteria,1R34Q@1224|Proteobacteria,42QTH@68525|delta/epsilon subdivisions,2WQ6V@28221|Deltaproteobacteria,43SXU@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM phosphatidate cytidylyltransferase	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
REGS1_k127_7414020_3	269799.Gmet_2767	9.772e-22	97.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42Y60@68525|delta/epsilon subdivisions,2WUR1@28221|Deltaproteobacteria,43T95@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_7414020_1	338966.Ppro_3307	1.306e-75	256.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42SDH@68525|delta/epsilon subdivisions,2WPPH@28221|Deltaproteobacteria,43V7T@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_7414020_0	575540.Isop_2606	1.093e-201	638.0	COG0114@1|root,COG0114@2|Bacteria,2IX95@203682|Planctomycetes	203682|Planctomycetes	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
REGS1_k127_7414020_2	269799.Gmet_2757	2.133e-54	193.0	COG3514@1|root,COG3514@2|Bacteria,1N3YP@1224|Proteobacteria	1224|Proteobacteria	S	BrnA antitoxin of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnA_antitoxin
REGS1_k127_7414020_4	1045855.DSC_05580	2.358e-11	67.0	COG2929@1|root,COG2929@2|Bacteria,1NG9V@1224|Proteobacteria,1SGBF@1236|Gammaproteobacteria,1X8WM@135614|Xanthomonadales	135614|Xanthomonadales	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	ko:K09803	-	-	-	-	ko00000	-	-	-	BrnT_toxin
REGS1_k127_7439654_11	269799.Gmet_2768	4.834e-81	271.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,42NGK@68525|delta/epsilon subdivisions,2WM29@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2768	NTP_transferase
REGS1_k127_7439654_10	243231.GSU1126	7.129e-93	310.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WMXB@28221|Deltaproteobacteria,43TTD@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_7439654_8	316067.Geob_3526	5.84e-105	348.0	28Q1P@1|root,2ZCJY@2|Bacteria,1RCE9@1224|Proteobacteria,42R28@68525|delta/epsilon subdivisions,2WN78@28221|Deltaproteobacteria,43U1V@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
REGS1_k127_7439654_2	443144.GM21_2546	2.022e-166	531.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,43U1Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
REGS1_k127_7439654_12	316067.Geob_3528	1.01e-77	267.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,43TZB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_7439654_3	269799.Gmet_2675	3.751e-158	506.0	COG3481@1|root,COG3481@2|Bacteria,1NH0C@1224|Proteobacteria,42Q7X@68525|delta/epsilon subdivisions,2WJW2@28221|Deltaproteobacteria,43T29@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	nucleic acid binding OB-fold tRNA helicase-type	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
REGS1_k127_7439654_0	243231.GSU1121	8.955e-196	624.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,42MT3@68525|delta/epsilon subdivisions,2WIK5@28221|Deltaproteobacteria,43T31@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	FAD dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,HI0933_like,Pyr_redox_2
REGS1_k127_7439654_16	316067.Geob_3531	2.261e-43	164.0	COG0745@1|root,COG0745@2|Bacteria,1NY95@1224|Proteobacteria,430KA@68525|delta/epsilon subdivisions,2WVQU@28221|Deltaproteobacteria,43V5V@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_7439654_4	269799.Gmet_2677	1.92e-151	488.0	COG0745@1|root,COG4191@1|root,COG0745@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42M6C@68525|delta/epsilon subdivisions,2WM3G@28221|Deltaproteobacteria,43S2C@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
REGS1_k127_7439654_13	269799.Gmet_2678	6.253e-61	213.0	COG0589@1|root,COG0589@2|Bacteria,1RA7K@1224|Proteobacteria,42V2P@68525|delta/epsilon subdivisions,2WRFB@28221|Deltaproteobacteria,43UR0@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Universal stress protein	usp-2	-	-	ko:K06149	-	-	-	-	ko00000	-	-	-	Usp
REGS1_k127_7439654_15	316067.Geob_3534	5.084e-55	196.0	COG0745@1|root,COG0745@2|Bacteria,1QXNI@1224|Proteobacteria,43C4G@68525|delta/epsilon subdivisions,2X7EW@28221|Deltaproteobacteria,43V0F@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_7439654_7	316067.Geob_3535	3.53e-114	372.0	COG3605@1|root,COG3605@2|Bacteria	2|Bacteria	T	phosphoenolpyruvate-protein phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,PEP-utilizers_C
REGS1_k127_7439654_17	269799.Gmet_2681	1.031e-39	161.0	COG1426@1|root,COG1426@2|Bacteria,1NN27@1224|Proteobacteria,42V2R@68525|delta/epsilon subdivisions,2WQP6@28221|Deltaproteobacteria,43V92@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4115)	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
REGS1_k127_7439654_9	316067.Geob_3537	6.038e-93	312.0	COG0457@1|root,COG0457@2|Bacteria,1MZGK@1224|Proteobacteria,42US4@68525|delta/epsilon subdivisions,2X72T@28221|Deltaproteobacteria,43UUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
REGS1_k127_7439654_1	338966.Ppro_0427	1.276e-176	559.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,43STZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
REGS1_k127_7439654_6	316067.Geob_3544	1.762e-140	450.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria,43TNU@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
REGS1_k127_7439654_19	456442.Mboo_1426	2.494e-10	69.0	arCOG11331@1|root,arCOG11331@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
REGS1_k127_7439654_14	573413.Spirs_2677	1.925e-60	213.0	COG2050@1|root,COG2050@2|Bacteria,2JAD0@203691|Spirochaetes	203691|Spirochaetes	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_7439654_5	269799.Gmet_0812	2.33e-148	476.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UD9@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_7650877_1	1121459.AQXE01000012_gene2280	2.605e-307	955.0	COG1960@1|root,COG1960@2|Bacteria,1PZ0R@1224|Proteobacteria,43E91@68525|delta/epsilon subdivisions,2X018@28221|Deltaproteobacteria,2M9QP@213115|Desulfovibrionales	28221|Deltaproteobacteria	I	PFAM Acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
REGS1_k127_7650877_2	1121456.ATVA01000019_gene1275	8.554e-279	868.0	COG0644@1|root,COG1145@1|root,COG0644@2|Bacteria,COG1145@2|Bacteria,1MVU6@1224|Proteobacteria,42PTE@68525|delta/epsilon subdivisions,2WKRZ@28221|Deltaproteobacteria,2MA78@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein-ubiquinone	-	-	1.5.5.1	ko:K00311	-	-	-	-	ko00000,ko01000	-	-	-	ETF_QO
REGS1_k127_7650877_18	237368.SCABRO_02363	3.779e-37	141.0	COG2827@1|root,COG2827@2|Bacteria,2J3VU@203682|Planctomycetes	203682|Planctomycetes	L	GIY-YIG catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	GIY-YIG
REGS1_k127_7650877_7	452637.Oter_3888	5.855e-127	410.0	COG2086@1|root,COG2086@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
REGS1_k127_7650877_6	452637.Oter_3889	4.421e-133	434.0	COG2025@1|root,COG2025@2|Bacteria	2|Bacteria	C	fatty acid beta-oxidation using acyl-CoA dehydrogenase	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	Acyl-CoA_dh_1,ETF,ETF_alpha
REGS1_k127_7650877_12	443144.GM21_0055	2.116e-89	301.0	arCOG11509@1|root,31KIR@2|Bacteria,1RGVE@1224|Proteobacteria,42T74@68525|delta/epsilon subdivisions,2WPQ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7650877_0	690850.Desaf_3477	0.0	1245.0	COG0376@1|root,COG0376@2|Bacteria,1MUBF@1224|Proteobacteria,42MZ4@68525|delta/epsilon subdivisions,2WJPB@28221|Deltaproteobacteria,2MABY@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
REGS1_k127_7650877_19	1121918.ARWE01000001_gene317	7.04e-34	132.0	COG2161@1|root,COG2161@2|Bacteria,1NFVK@1224|Proteobacteria,430TQ@68525|delta/epsilon subdivisions,2WVWU@28221|Deltaproteobacteria,43V3R@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	toxin-antitoxin pair type II binding	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
REGS1_k127_7650877_20	316055.RPE_3247	3.026e-26	121.0	2DP71@1|root,330U0@2|Bacteria,1Q0FC@1224|Proteobacteria,2UK79@28211|Alphaproteobacteria,3K1XH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
REGS1_k127_7650877_5	240015.ACP_3248	6.868e-144	470.0	2ARXV@1|root,31H9T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
REGS1_k127_7650877_9	398767.Glov_3676	1.839e-109	364.0	COG2813@1|root,COG2813@2|Bacteria	2|Bacteria	J	rRNA (guanine-N2-)-methyltransferase activity	crtF	GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.1.210,2.1.1.304,2.1.1.333	ko:K09846,ko:K13604,ko:K21460	ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110	-	R07521,R07524,R07527,R07529,R07533,R07535,R09063	RC00003,RC01662,RC02082	ko00000,ko00001,ko01000	-	-	-	Dimerisation2,Methyltransf_2,Methyltransf_25
REGS1_k127_7650877_8	443143.GM18_1262	5.212e-118	381.0	COG4832@1|root,COG4832@2|Bacteria,1RBGY@1224|Proteobacteria,42VX0@68525|delta/epsilon subdivisions,2WRUN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
REGS1_k127_7650877_14	1114970.PSF113_4081	4.421e-69	241.0	COG1073@1|root,COG1073@2|Bacteria,1RGMF@1224|Proteobacteria,1SNV9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
REGS1_k127_7650877_10	269799.Gmet_1815	1.366e-104	346.0	COG0655@1|root,COG0655@2|Bacteria,1N3NQ@1224|Proteobacteria,42TRR@68525|delta/epsilon subdivisions,2WQ13@28221|Deltaproteobacteria,43VWV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_7650877_16	243231.GSU0173	3.833e-61	216.0	COG3542@1|root,COG4728@1|root,COG3542@2|Bacteria,COG4728@2|Bacteria,1RHBE@1224|Proteobacteria,42T2P@68525|delta/epsilon subdivisions,2WPQ3@28221|Deltaproteobacteria,43USB@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
REGS1_k127_7650877_15	748280.NH8B_0019	1.966e-61	213.0	COG0730@1|root,COG0730@2|Bacteria,1PYEK@1224|Proteobacteria,2W2DY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
REGS1_k127_7650877_22	985867.AEWF01000001_gene2004	3.213e-06	60.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	tlpA	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
REGS1_k127_7650877_11	243231.GSU3306	1.231e-99	344.0	COG5386@1|root,COG5386@2|Bacteria,1QWPV@1224|Proteobacteria,43BUN@68525|delta/epsilon subdivisions,2X75R@28221|Deltaproteobacteria,43UJG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
REGS1_k127_7650877_4	316067.Geob_1250	9.772e-158	513.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42YS1@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	sensor histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,CHASE3,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_7650877_17	316067.Geob_1251	9.785e-56	204.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,1NSQ1@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA,PAS_4,PAS_9,Response_reg,dCache_1
REGS1_k127_7650877_3	243231.GSU1000	2.376e-169	542.0	28HIY@1|root,2Z7U8@2|Bacteria,1MY3K@1224|Proteobacteria,42QIR@68525|delta/epsilon subdivisions,2WME0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7650877_13	1123376.AUIU01000012_gene1420	1.389e-85	291.0	COG0661@1|root,COG0661@2|Bacteria,3J0ZH@40117|Nitrospirae	40117|Nitrospirae	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
REGS1_k127_7662602_2	243231.GSU0522	3.552e-210	660.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43TW5@69541|Desulfuromonadales	28221|Deltaproteobacteria	JKL	DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlB	-	3.6.4.13	ko:K03732	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03019	-	-	-	DEAD,Helicase_C,R3H
REGS1_k127_7662602_0	269799.Gmet_2638	0.0	1217.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,42PRT@68525|delta/epsilon subdivisions,2WIWH@28221|Deltaproteobacteria,43U6B@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2638	PEPCK_C,PEPCK_N
REGS1_k127_7662602_3	443143.GM18_0460	1.582e-180	571.0	COG1740@1|root,COG1740@2|Bacteria,1MWAC@1224|Proteobacteria,42MI0@68525|delta/epsilon subdivisions,2WIW4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM hydrogenase (NiFe) small subunit (hydA)	hyaS	-	1.12.2.1,1.12.99.6	ko:K06282,ko:K18008	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_3332	NiFe_hyd_SSU_C,Oxidored_q6,TAT_signal
REGS1_k127_7662602_1	398767.Glov_2055	9.955e-317	976.0	COG0374@1|root,COG0374@2|Bacteria,1MWFJ@1224|Proteobacteria,42M4S@68525|delta/epsilon subdivisions,2WJQS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hyaL	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
REGS1_k127_7662602_5	243231.GSU0121	6.297e-76	260.0	COG1969@1|root,COG1969@2|Bacteria,1MU87@1224|Proteobacteria,42NQ3@68525|delta/epsilon subdivisions,2WN6Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit	hyaB	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
REGS1_k127_7662602_7	269799.Gmet_3329	6.194e-57	204.0	COG0680@1|root,COG0680@2|Bacteria,1RE1C@1224|Proteobacteria,42REH@68525|delta/epsilon subdivisions,2WPXK@28221|Deltaproteobacteria,43VTP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM peptidase M52 hydrogen uptake protein	hyaP	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	iAF987.Gmet_3329	HycI
REGS1_k127_7662602_6	269799.Gmet_2836	1.677e-69	245.0	COG3170@1|root,COG3170@2|Bacteria,1REZ7@1224|Proteobacteria,42RFW@68525|delta/epsilon subdivisions,2WS8K@28221|Deltaproteobacteria,43VBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
REGS1_k127_7662602_4	443143.GM18_3845	7.272e-135	441.0	COG2040@1|root,COG2040@2|Bacteria,1MUXU@1224|Proteobacteria,42UXG@68525|delta/epsilon subdivisions,2WQGE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Homocysteine S-methyltransferase	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
REGS1_k127_7662602_8	338966.Ppro_2802	6.801e-29	116.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,43T61@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
REGS1_k127_7807950_12	316067.Geob_1834	1.528e-10	64.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_7807950_9	1047013.AQSP01000106_gene1773	1.107e-41	173.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
REGS1_k127_7807950_1	269799.Gmet_0568	3.035e-115	378.0	COG3221@1|root,COG3221@2|Bacteria,1NPBT@1224|Proteobacteria,42NX8@68525|delta/epsilon subdivisions,2X5DW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
REGS1_k127_7807950_8	1499967.BAYZ01000096_gene4306	1.001e-43	179.0	COG3119@1|root,COG5652@1|root,COG3119@2|Bacteria,COG5652@2|Bacteria,2NRYS@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase,VanZ
REGS1_k127_7807950_6	1047013.AQSP01000106_gene1773	7.014e-49	193.0	COG3119@1|root,COG3119@2|Bacteria,2NR0Q@2323|unclassified Bacteria	2|Bacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4976,Sulfatase
REGS1_k127_7807950_2	1267533.KB906740_gene247	2.47e-99	333.0	COG1234@1|root,COG1234@2|Bacteria,3Y7KR@57723|Acidobacteria	57723|Acidobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
REGS1_k127_7807950_7	331869.BAL199_18541	1.529e-48	185.0	COG1834@1|root,COG1834@2|Bacteria,1R7NG@1224|Proteobacteria,2U4ZK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
REGS1_k127_7807950_3	179408.Osc7112_0936	2.043e-81	288.0	COG4424@1|root,COG4424@2|Bacteria,1G544@1117|Cyanobacteria,1HAVY@1150|Oscillatoriales	1117|Cyanobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Asp_Arg_Hydrox,Sulfotransfer_3
REGS1_k127_7807950_4	111780.Sta7437_1803	4.35e-69	247.0	COG0615@1|root,COG0615@2|Bacteria,1G4EC@1117|Cyanobacteria,3VMYE@52604|Pleurocapsales	1117|Cyanobacteria	IM	PFAM sulfotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
REGS1_k127_7807950_10	316067.Geob_3281	1.649e-38	151.0	2C6P2@1|root,33C1K@2|Bacteria,1NI6K@1224|Proteobacteria,42WBY@68525|delta/epsilon subdivisions,2WRCU@28221|Deltaproteobacteria,43VJ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
REGS1_k127_7807950_5	1463936.JOJI01000031_gene2178	6.572e-60	215.0	COG0500@1|root,COG2226@2|Bacteria,2INQ9@201174|Actinobacteria	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
REGS1_k127_7807950_0	316067.Geob_2842	5.224e-171	558.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WJR1@28221|Deltaproteobacteria,43S2F@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	AsmA-like C-terminal region	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2,DUF748
REGS1_k127_7807950_11	509191.AEDB02000048_gene4684	7.747e-15	80.0	COG1032@1|root,COG1032@2|Bacteria,1UYAF@1239|Firmicutes,24D1D@186801|Clostridia,3WKPM@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
REGS1_k127_782346_0	443144.GM21_2279	0.0	1438.0	COG1615@1|root,COG1615@2|Bacteria,1MZ5A@1224|Proteobacteria,42M4M@68525|delta/epsilon subdivisions,2WIPI@28221|Deltaproteobacteria,43SU8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
REGS1_k127_782346_3	316067.Geob_2202	4.039e-227	715.0	COG1227@1|root,COG4109@1|root,COG1227@2|Bacteria,COG4109@2|Bacteria,1P9JN@1224|Proteobacteria,42N0W@68525|delta/epsilon subdivisions,2WK0Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	DHHA2 domain protein	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
REGS1_k127_782346_19	243231.GSU1568	3.799e-32	127.0	COG3809@1|root,COG3809@2|Bacteria,1N6ZY@1224|Proteobacteria,42VNA@68525|delta/epsilon subdivisions,2WRKK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
REGS1_k127_782346_6	316067.Geob_2200	5.302e-164	526.0	COG0628@1|root,COG0628@2|Bacteria,1MW34@1224|Proteobacteria	1224|Proteobacteria	S	membrane	IV02_12080	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_782346_10	398767.Glov_0551	3.135e-87	299.0	COG2119@1|root,COG2119@2|Bacteria,1RDDV@1224|Proteobacteria	1224|Proteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
REGS1_k127_782346_8	404380.Gbem_1936	1.414e-131	422.0	COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Integral membrane protein TerC	-	-	-	-	-	-	-	-	-	-	-	-	TerC
REGS1_k127_782346_1	316067.Geob_2314	4.5e-315	980.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,43TNJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	histidine kinase, HAMP	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
REGS1_k127_782346_2	269799.Gmet_0760	2.907e-231	727.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
REGS1_k127_782346_20	316067.Geob_2317	1.313e-30	123.0	COG3937@1|root,COG3937@2|Bacteria,1NCTH@1224|Proteobacteria,42VYI@68525|delta/epsilon subdivisions,2WS2X@28221|Deltaproteobacteria,43VFM@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	granule-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Phasin
REGS1_k127_782346_22	269799.Gmet_0753	2.493e-25	108.0	COG3071@1|root,COG3071@2|Bacteria,1N6Y8@1224|Proteobacteria,42WU5@68525|delta/epsilon subdivisions,2WRRS@28221|Deltaproteobacteria,43SRB@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Protein of unknown function (DUF2905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2905
REGS1_k127_782346_12	269799.Gmet_0752	3.372e-81	273.0	COG1636@1|root,COG1636@2|Bacteria,1MUG5@1224|Proteobacteria,42M1E@68525|delta/epsilon subdivisions,2WMR5@28221|Deltaproteobacteria,43UNP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
REGS1_k127_782346_21	243231.GSU0192	5.362e-26	110.0	2DG3E@1|root,2ZUAA@2|Bacteria,1P6E0@1224|Proteobacteria,4337Y@68525|delta/epsilon subdivisions,2WYEX@28221|Deltaproteobacteria,43VXQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3553
REGS1_k127_782346_18	398767.Glov_3009	5.477e-35	134.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WX4U@28221|Deltaproteobacteria,43VFT@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_782346_4	269799.Gmet_2573	1.959e-209	658.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43T9G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	helicase superfamily c-terminal domain	rhlE-2	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
REGS1_k127_782346_11	1236959.BAMT01000001_gene1048	8.63e-87	293.0	COG2227@1|root,COG2227@2|Bacteria,1R9ZR@1224|Proteobacteria,2VYFC@28216|Betaproteobacteria,2KNIJ@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
REGS1_k127_782346_14	243231.GSU1078	1.46e-74	258.0	COG0593@1|root,COG0593@2|Bacteria,1QTI4@1224|Proteobacteria,42ZGP@68525|delta/epsilon subdivisions,2WV11@28221|Deltaproteobacteria,43UPM@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM Chromosomal replication initiator, DnaA	hda	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA
REGS1_k127_782346_5	404380.Gbem_3316	1.258e-175	554.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,43TWH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
REGS1_k127_782346_13	243231.GSU1076	2.099e-75	259.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,43U6G@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
REGS1_k127_782346_15	316067.Geob_2325	8.624e-72	245.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,43US0@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
REGS1_k127_782346_7	316067.Geob_2326	5.653e-137	438.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,42N7Q@68525|delta/epsilon subdivisions,2WJ1I@28221|Deltaproteobacteria,43T68@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	regulation of RNA biosynthetic process	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
REGS1_k127_782346_9	243231.GSU1072	2.291e-105	347.0	COG1414@1|root,COG1414@2|Bacteria,1R66I@1224|Proteobacteria	1224|Proteobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
REGS1_k127_782346_16	443144.GM21_2698	1.412e-56	199.0	COG3162@1|root,COG3162@2|Bacteria,1N9T2@1224|Proteobacteria,430YF@68525|delta/epsilon subdivisions,2WW0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF485	-	-	-	-	-	-	-	-	-	-	-	-	DUF485
REGS1_k127_782346_17	443144.GM21_2699	3.453e-42	160.0	COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,42MJE@68525|delta/epsilon subdivisions,2WK5T@28221|Deltaproteobacteria,43TCV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	aplA	-	-	ko:K14393	-	-	-	-	ko00000,ko02000	2.A.21.7	-	iAF987.Gmet_0739	SSF
REGS1_k127_788507_5	316067.Geob_2096	1.967e-91	306.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
REGS1_k127_788507_1	243231.GSU2270	9.917e-195	614.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,43T9B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
REGS1_k127_788507_0	269799.Gmet_2360	1.424e-280	867.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,42M90@68525|delta/epsilon subdivisions,2WJ9G@28221|Deltaproteobacteria,43SYZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
REGS1_k127_788507_6	404380.Gbem_0835	1.26e-59	222.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,43VN4@69541|Desulfuromonadales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
REGS1_k127_788507_8	316067.Geob_3089	4.002e-53	199.0	2F1GM@1|root,33UH5@2|Bacteria,1NUBU@1224|Proteobacteria,42ZFW@68525|delta/epsilon subdivisions,2WUSB@28221|Deltaproteobacteria,43UKQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4140
REGS1_k127_788507_7	316067.Geob_3090	1.151e-54	197.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,42TNB@68525|delta/epsilon subdivisions,2WQIG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Peptidyl-prolyl cis-trans	fbp	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_788507_2	443143.GM18_3491	1.287e-194	615.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42PTC@68525|delta/epsilon subdivisions,2WM3S@28221|Deltaproteobacteria,43TWP@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
REGS1_k127_788507_4	316067.Geob_3092	3.513e-104	345.0	COG0791@1|root,COG3087@1|root,COG0791@2|Bacteria,COG3087@2|Bacteria,1N0EE@1224|Proteobacteria,42V3C@68525|delta/epsilon subdivisions,2WRIP@28221|Deltaproteobacteria,43SY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	DM	PFAM NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SPOR
REGS1_k127_788507_3	316067.Geob_3093	6.277e-185	581.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria,43U2J@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_788507_9	404380.Gbem_1002	9.202e-05	45.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,42MKD@68525|delta/epsilon subdivisions,2WIZP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_7913142_2	290512.Paes_2151	3.523e-128	423.0	COG3547@1|root,COG3547@2|Bacteria,1FEII@1090|Chlorobi	1090|Chlorobi	L	transposase IS116 IS110 IS902 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_7913142_4	1229487.AMYW01000034_gene3103	9.405e-40	156.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	Trypsin_2
REGS1_k127_7913142_1	316067.Geob_0621	4.122e-134	435.0	COG1242@1|root,COG1242@2|Bacteria,1MUYF@1224|Proteobacteria,42PX9@68525|delta/epsilon subdivisions,2WIPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART Elongator protein 3 MiaB NifB	yhcC-1	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
REGS1_k127_7913142_3	243231.GSU1102	2.785e-91	306.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,43TEF@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	response regulator	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_7913142_0	269799.Gmet_2694	7.523e-145	474.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
REGS1_k127_801859_15	316067.Geob_3388	1.943e-34	133.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
REGS1_k127_801859_16	443144.GM21_0063	4.589e-27	116.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,42QB7@68525|delta/epsilon subdivisions,2WM6Y@28221|Deltaproteobacteria,43UAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,Response_reg
REGS1_k127_801859_5	269799.Gmet_1082	5.801e-164	530.0	COG2204@1|root,COG2204@2|Bacteria,1PAPS@1224|Proteobacteria,42NMK@68525|delta/epsilon subdivisions,2WK6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_801859_13	1244869.H261_09277	2.694e-56	224.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,MHYT,PAS,PAS_3,PAS_4,PAS_9,dCache_1
REGS1_k127_801859_9	316067.Geob_3691	1.627e-102	365.0	COG3920@1|root,COG4191@1|root,COG3920@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM1A@28221|Deltaproteobacteria,43U1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
REGS1_k127_801859_17	1280390.CBQR020000166_gene4414	2.577e-22	116.0	COG5297@1|root,COG5297@2|Bacteria,1V1T2@1239|Firmicutes,4HUDU@91061|Bacilli,26S1Z@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase family 6	guxA	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_3,Glyco_hydro_6,fn3
REGS1_k127_801859_1	316067.Geob_1835	6.102e-300	1022.0	COG1520@1|root,COG4733@1|root,COG1520@2|Bacteria,COG4733@2|Bacteria,1P31B@1224|Proteobacteria,42VDF@68525|delta/epsilon subdivisions,2WRBJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SBBP,VWD,fn3
REGS1_k127_801859_0	316067.Geob_1834	0.0	1744.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_801859_4	316067.Geob_3642	2.395e-171	544.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,42MDN@68525|delta/epsilon subdivisions,2WINX@28221|Deltaproteobacteria,43TEU@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_801859_12	316067.Geob_3643	1.514e-64	222.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,43V2N@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
REGS1_k127_801859_11	269799.Gmet_0606	9.398e-72	245.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,43UNF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
REGS1_k127_801859_10	269799.Gmet_0605	2.868e-92	308.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,43T8Y@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
REGS1_k127_801859_2	269799.Gmet_0603	1.012e-218	681.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,42MDM@68525|delta/epsilon subdivisions,2WJ5Y@28221|Deltaproteobacteria,43S81@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_801859_14	443144.GM21_0610	9.66e-43	159.0	29Q4T@1|root,32BQP@2|Bacteria,1N5SH@1224|Proteobacteria	1224|Proteobacteria	S	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP
REGS1_k127_801859_3	243231.GSU2879	4.208e-216	674.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,43TZH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_801859_7	269799.Gmet_2815	1.295e-129	424.0	COG1215@1|root,COG1215@2|Bacteria,1PC79@1224|Proteobacteria,42QYP@68525|delta/epsilon subdivisions,2X6HG@28221|Deltaproteobacteria,43UDX@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyl transferase family group 2	hpnI	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
REGS1_k127_801859_6	316067.Geob_1495	1.099e-137	443.0	COG0388@1|root,COG0388@2|Bacteria,1RIQI@1224|Proteobacteria,42T6J@68525|delta/epsilon subdivisions,2WPVY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
REGS1_k127_801859_8	398767.Glov_2228	5.817e-106	346.0	COG0171@1|root,COG0171@2|Bacteria,1MU9U@1224|Proteobacteria,42N86@68525|delta/epsilon subdivisions,2WIV4@28221|Deltaproteobacteria,43VVZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	nadE	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
REGS1_k127_8032755_3	316067.Geob_2404	6.639e-31	123.0	COG3620@1|root,COG3620@2|Bacteria,1N84U@1224|Proteobacteria,43BV6@68525|delta/epsilon subdivisions,2WSBR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_8032755_2	443143.GM18_1785	2.957e-36	141.0	COG0745@1|root,COG0745@2|Bacteria,1NZKJ@1224|Proteobacteria,430ZP@68525|delta/epsilon subdivisions,2WW45@28221|Deltaproteobacteria,43V78@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	cheY40H-5	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_8032755_1	485916.Dtox_2814	3.793e-120	409.0	COG2202@1|root,COG3437@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,261WQ@186807|Peptococcaceae	186801|Clostridia	T	HD domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,HD,HD_5
REGS1_k127_8032755_0	316067.Geob_1318	0.0	1770.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,43RZ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Glutamate synthase central domain	gltS	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
REGS1_k127_806415_2	269799.Gmet_2626	1.495e-63	222.0	2DKVG@1|root,30GRY@2|Bacteria,1RDQT@1224|Proteobacteria,42V8G@68525|delta/epsilon subdivisions,2WRP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
REGS1_k127_806415_0	316067.Geob_1143	1.696e-262	812.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42YJ3@68525|delta/epsilon subdivisions,2WUQQ@28221|Deltaproteobacteria,43SUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
REGS1_k127_806415_1	243231.GSU0116	3.06e-115	377.0	COG0744@1|root,COG0744@2|Bacteria,1RB3Z@1224|Proteobacteria,43B0J@68525|delta/epsilon subdivisions,2WN47@28221|Deltaproteobacteria,43SG0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
REGS1_k127_8107088_4	640081.Dsui_3372	1.558e-209	672.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,2VK1A@28216|Betaproteobacteria,2KVYD@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8107088_9	338966.Ppro_3235	9.48e-197	626.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,43THP@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_8107088_19	338966.Ppro_3234	1.547e-113	372.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2WMVB@28221|Deltaproteobacteria,43TUK@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_8107088_15	338966.Ppro_3233	1.313e-142	464.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,43SP7@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
REGS1_k127_8107088_8	243231.GSU3062	8.419e-198	631.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,43U0H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_8107088_11	316067.Geob_0786	1.338e-177	563.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,43S7V@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
REGS1_k127_8107088_3	269799.Gmet_0416	1.514e-237	737.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,43SXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
REGS1_k127_8107088_20	316067.Geob_0784	2.599e-82	282.0	COG1589@1|root,COG1589@2|Bacteria,1RDX7@1224|Proteobacteria,42VCZ@68525|delta/epsilon subdivisions,2WRVM@28221|Deltaproteobacteria,43UHQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Essential cell division protein	ftsQ	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
REGS1_k127_8107088_16	269799.Gmet_0415	2.267e-134	436.0	COG1181@1|root,COG1589@1|root,COG1181@2|Bacteria,COG1589@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,43U8P@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Cell wall formation	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
REGS1_k127_8107088_18	338966.Ppro_3287	6.404e-122	397.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42P86@68525|delta/epsilon subdivisions,2WN8T@28221|Deltaproteobacteria,43TM2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
REGS1_k127_8107088_1	338966.Ppro_3288	9.071e-275	847.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,43U76@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_8107088_21	338966.Ppro_3212	8.301e-73	248.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,43UP4@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
REGS1_k127_8107088_14	316067.Geob_0780	4.41e-147	477.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,43UB0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
REGS1_k127_8107088_13	404380.Gbem_0490	9.631e-151	485.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,43TAE@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
REGS1_k127_8107088_7	398767.Glov_0672	7.032e-198	625.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
REGS1_k127_8107088_5	316067.Geob_0777	2.066e-202	633.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,43UBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
REGS1_k127_8107088_12	243231.GSU3073	6.392e-166	534.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,43TX6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_8107088_6	338966.Ppro_3294	3.417e-198	629.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,43T9W@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_8107088_2	269799.Gmet_0406	1.817e-273	856.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,43TGP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Penicillin-binding protein, dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
REGS1_k127_8107088_23	243231.GSU3076	1.313e-31	126.0	COG3116@1|root,COG3116@2|Bacteria,1NY4P@1224|Proteobacteria,430ZK@68525|delta/epsilon subdivisions,2WW3Y@28221|Deltaproteobacteria,43VC8@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Essential cell division protein	ftsL	-	-	-	-	-	-	-	-	-	-	-	DivIC
REGS1_k127_8107088_17	243231.GSU3077	7.332e-129	418.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,43TQT@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
REGS1_k127_8107088_22	269799.Gmet_0403	5.626e-67	231.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria,43V7I@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
REGS1_k127_8107088_10	316067.Geob_0383	4.534e-185	587.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,43UJ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
REGS1_k127_8107088_0	316067.Geob_0384	0.0	1186.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,43T20@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
REGS1_k127_8136514_3	316067.Geob_1537	2.659e-152	487.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,42P56@68525|delta/epsilon subdivisions,2WK5J@28221|Deltaproteobacteria,43TSK@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
REGS1_k127_8136514_17	269799.Gmet_1266	2.434e-33	129.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,42V0K@68525|delta/epsilon subdivisions,2WR92@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM Cold-shock protein, DNA-binding	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_8136514_5	404380.Gbem_2740	1.79e-151	499.0	COG1629@1|root,COG4886@1|root,COG4771@2|Bacteria,COG4886@2|Bacteria,1P67X@1224|Proteobacteria,4323Z@68525|delta/epsilon subdivisions,2WXVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TonB-dependent receptor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8136514_18	316067.Geob_2288	1.441e-31	134.0	COG0775@1|root,COG0775@2|Bacteria,1Q1C0@1224|Proteobacteria,43EX0@68525|delta/epsilon subdivisions,2WRFZ@28221|Deltaproteobacteria,43V4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM purine or other phosphorylase family 1	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_8136514_12	398767.Glov_3185	1.139e-67	235.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,42U8G@68525|delta/epsilon subdivisions,2WQPS@28221|Deltaproteobacteria,43USX@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaC protein	-	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
REGS1_k127_8136514_1	243231.GSU0814	4.954e-177	565.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PD6@68525|delta/epsilon subdivisions,2WK6G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_8136514_14	269799.Gmet_0786	1.331e-58	206.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,42SCT@68525|delta/epsilon subdivisions,2WPA7@28221|Deltaproteobacteria,43V10@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
REGS1_k127_8136514_8	269799.Gmet_0787	2.178e-122	396.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NI4@68525|delta/epsilon subdivisions,2WKRT@28221|Deltaproteobacteria,43U5X@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran,GGDEF
REGS1_k127_8136514_6	243231.GSU0817	1.978e-127	411.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,43UCE@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
REGS1_k127_8136514_7	316067.Geob_1378	2.384e-125	411.0	COG4786@1|root,COG4786@2|Bacteria,1MZXB@1224|Proteobacteria,42MTK@68525|delta/epsilon subdivisions,2WM8U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Protein of unknown function (DUF2950)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2950
REGS1_k127_8136514_10	316067.Geob_1379	1.21e-117	394.0	COG3115@1|root,COG3115@2|Bacteria,1QVM5@1224|Proteobacteria,43CDH@68525|delta/epsilon subdivisions,2X7PC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	Protein of unknown function (DUF3300)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3300
REGS1_k127_8136514_4	398767.Glov_1726	6.949e-152	518.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42NK9@68525|delta/epsilon subdivisions,2WMCQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_9,Response_reg
REGS1_k127_8136514_0	404380.Gbem_0063	0.0	1681.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43T46@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296,ko:K07788,ko:K07789,ko:K18138	ko01501,ko01503,ko02020,map01501,map01503,map02020	M00647,M00648,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
REGS1_k127_8136514_2	404380.Gbem_0064	1.156e-171	546.0	COG0845@1|root,COG0845@2|Bacteria,1MW65@1224|Proteobacteria,42NJG@68525|delta/epsilon subdivisions,2WJ8R@28221|Deltaproteobacteria,43US6@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K07799	ko02020,map02020	M00648	-	-	ko00000,ko00001,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_8136514_13	338966.Ppro_0036	7.427e-59	210.0	COG3238@1|root,COG3238@2|Bacteria,1N6ZC@1224|Proteobacteria,42U5S@68525|delta/epsilon subdivisions,2WQRJ@28221|Deltaproteobacteria,43SQN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative inner membrane exporter, YdcZ	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
REGS1_k127_8136514_9	269799.Gmet_2572	8.362e-119	390.0	COG0500@1|root,COG2835@1|root,COG2226@2|Bacteria,COG2835@2|Bacteria,1R5RG@1224|Proteobacteria,42NHW@68525|delta/epsilon subdivisions,2WKI8@28221|Deltaproteobacteria,43TKH@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Trm112p
REGS1_k127_8136514_15	309801.trd_1948	6.046e-41	161.0	COG0451@1|root,COG0451@2|Bacteria,2G8UV@200795|Chloroflexi,27Z0H@189775|Thermomicrobia	189775|Thermomicrobia	M	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_8136514_16	1499967.BAYZ01000017_gene6232	1.646e-35	138.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_8136514_11	1499967.BAYZ01000017_gene6233	1.069e-112	372.0	COG0693@1|root,COG0693@2|Bacteria	2|Bacteria	S	protein deglycation	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,ThiJ_like
REGS1_k127_8147528_21	1304872.JAGC01000003_gene3192	3.726e-26	112.0	COG2944@1|root,COG2944@2|Bacteria,1N5H0@1224|Proteobacteria,43B8E@68525|delta/epsilon subdivisions,2X6MS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	-
REGS1_k127_8147528_20	91604.ID47_01230	1.647e-26	112.0	COG4737@1|root,COG4737@2|Bacteria,1N7N5@1224|Proteobacteria,2UGH7@28211|Alphaproteobacteria,47GBY@766|Rickettsiales	766|Rickettsiales	S	Cytotoxic translational repressor of toxin-antitoxin stability system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8147528_0	404380.Gbem_2725	2.524e-214	676.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,42M2G@68525|delta/epsilon subdivisions,2WJ80@28221|Deltaproteobacteria,43RYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
REGS1_k127_8147528_25	909663.KI867150_gene317	1.464e-19	89.0	2EINH@1|root,33CDW@2|Bacteria,1NN5W@1224|Proteobacteria,437XZ@68525|delta/epsilon subdivisions,2X37U@28221|Deltaproteobacteria,2MSBT@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8147528_11	243231.GSU0792	6.279e-77	265.0	COG3332@1|root,COG3332@2|Bacteria,1RDBS@1224|Proteobacteria,42QS8@68525|delta/epsilon subdivisions,2WMV7@28221|Deltaproteobacteria,43SGZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Transport and Golgi organisation 2	-	-	-	-	-	-	-	-	-	-	-	-	TANGO2
REGS1_k127_8147528_22	398767.Glov_0189	5.365e-25	105.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2WNUH@28221|Deltaproteobacteria,43VMR@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Thioredoxin	trx-3	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
REGS1_k127_8147528_19	398767.Glov_0189	2.836e-27	112.0	COG3118@1|root,COG3118@2|Bacteria,1RHUA@1224|Proteobacteria,42S1N@68525|delta/epsilon subdivisions,2WNUH@28221|Deltaproteobacteria,43VMR@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Thioredoxin	trx-3	-	1.8.1.8	ko:K03672	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Thioredoxin
REGS1_k127_8147528_28	690850.Desaf_0357	8.377e-17	83.0	COG2155@1|root,COG2155@2|Bacteria,1N77I@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
REGS1_k127_8147528_24	243231.GSU1938	8.259e-22	104.0	COG4105@1|root,COG4105@2|Bacteria,1P1T1@1224|Proteobacteria,431YI@68525|delta/epsilon subdivisions,2WWV8@28221|Deltaproteobacteria,43VJA@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8147528_5	316067.Geob_2382	1.058e-141	462.0	COG2199@1|root,COG3850@1|root,COG2199@2|Bacteria,COG3850@2|Bacteria,1NT1K@1224|Proteobacteria,42R1P@68525|delta/epsilon subdivisions,2WN0S@28221|Deltaproteobacteria,43U9N@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Nucleotide cyclase, HAMP and GGDEF-related domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HAMP
REGS1_k127_8147528_7	941449.dsx2_3235	6.79e-109	365.0	COG4292@1|root,COG4292@2|Bacteria,1QWAK@1224|Proteobacteria,42ZNP@68525|delta/epsilon subdivisions,2WUUY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	K channel, inward rectifier, conserved region 2 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	IRK,LtrA
REGS1_k127_8147528_13	269799.Gmet_0234	8.403e-66	228.0	2CESE@1|root,32S0D@2|Bacteria,1RHTD@1224|Proteobacteria	1224|Proteobacteria	S	Glycine-zipper domain	-	-	-	-	-	-	-	-	-	-	-	-	Gly-zipper_OmpA
REGS1_k127_8147528_12	269799.Gmet_2374	1.11e-68	238.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,42TFN@68525|delta/epsilon subdivisions,2WP7M@28221|Deltaproteobacteria,43SNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Isochorismatase family	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
REGS1_k127_8147528_2	316067.Geob_3431	5.925e-191	606.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,43S4K@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
REGS1_k127_8147528_9	338966.Ppro_2838	1.788e-94	313.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,42QXM@68525|delta/epsilon subdivisions,2WMZI@28221|Deltaproteobacteria,43W1B@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_8147528_31	469008.B21_00516	2.553e-09	63.0	2CJNH@1|root,32U6W@2|Bacteria,1N1FA@1224|Proteobacteria,1S98N@1236|Gammaproteobacteria,3XR1S@561|Escherichia	1236|Gammaproteobacteria	S	Bor protein	iss	-	-	-	-	-	-	-	-	-	-	-	Lambda_Bor
REGS1_k127_8147528_33	218491.ECA2067	2.458e-06	54.0	2CJNH@1|root,32U6W@2|Bacteria,1N1FA@1224|Proteobacteria,1S98N@1236|Gammaproteobacteria,1MST6@122277|Pectobacterium	1236|Gammaproteobacteria	S	Bor protein	borD	GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0032026,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071286	-	-	-	-	-	-	-	-	-	-	Lambda_Bor
REGS1_k127_8147528_15	443143.GM18_1785	3.398e-40	153.0	COG0745@1|root,COG0745@2|Bacteria,1NZKJ@1224|Proteobacteria,430ZP@68525|delta/epsilon subdivisions,2WW45@28221|Deltaproteobacteria,43V78@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	cheY40H-5	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_8147528_16	290397.Adeh_1899	1.565e-34	147.0	2DM7I@1|root,32UGD@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8147528_23	323848.Nmul_A1742	5.592e-22	101.0	2CMHI@1|root,32SET@2|Bacteria,1NDKZ@1224|Proteobacteria,2W4U6@28216|Betaproteobacteria,373BR@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8147528_18	387093.SUN_0863	5.141e-29	130.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,CotH,F5_F8_type_C,FIVAR,LTD,Metallophos
REGS1_k127_8147528_8	243231.GSU0715	2.813e-103	342.0	COG3103@1|root,COG3103@2|Bacteria,1R90G@1224|Proteobacteria,42YW1@68525|delta/epsilon subdivisions,2WTI8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	N-acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2
REGS1_k127_8147528_30	396588.Tgr7_2258	1.736e-12	78.0	2E23K@1|root,32XAV@2|Bacteria,1N7MZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8147528_6	395494.Galf_1683	1.088e-116	385.0	28IH6@1|root,2Z8IF@2|Bacteria,1R4Z0@1224|Proteobacteria,2VRWN@28216|Betaproteobacteria,44WIZ@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8147528_10	706587.Desti_2376	8.199e-78	272.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,42R2E@68525|delta/epsilon subdivisions,2WMYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glycyl-radical enzyme activating protein family	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_8147528_3	706587.Desti_2378	4.697e-188	615.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	formate C-acetyltransferase glycine radical	-	-	-	-	-	-	-	-	-	-	-	-	Gly_radical,PFL-like
REGS1_k127_8147528_4	316067.Geob_3256	9.402e-163	518.0	COG1409@1|root,COG1409@2|Bacteria,1R5W3@1224|Proteobacteria,42N0A@68525|delta/epsilon subdivisions,2WKFZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
REGS1_k127_8147528_1	443143.GM18_1788	1e-200	651.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria,43T5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	mcp40H-17	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,MCPsignal
REGS1_k127_8147528_14	1121918.ARWE01000001_gene432	2.472e-41	175.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria,43T5B@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	mcp40H-17	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,MCPsignal
REGS1_k127_8268721_4	269799.Gmet_2774	4.383e-65	225.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,42PVD@68525|delta/epsilon subdivisions,2WM2C@28221|Deltaproteobacteria,43SUX@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Pfam:UPF0118	-	-	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
REGS1_k127_8268721_2	316067.Geob_0821	1.188e-113	376.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria	1224|Proteobacteria	K	permease	perM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
REGS1_k127_8268721_1	1234364.AMSF01000085_gene2891	6.337e-130	426.0	COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,1RV34@1236|Gammaproteobacteria,1XDGQ@135614|Xanthomonadales	135614|Xanthomonadales	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
REGS1_k127_8268721_5	443143.GM18_1040	6.415e-64	226.0	28NH4@1|root,2ZBJ2@2|Bacteria,1RADQ@1224|Proteobacteria,42UWF@68525|delta/epsilon subdivisions,2X6PD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8268721_0	398767.Glov_2052	1.763e-164	528.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,42PVW@68525|delta/epsilon subdivisions,2WIMX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
REGS1_k127_8268721_3	316067.Geob_0816	3.05e-79	269.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,42QQP@68525|delta/epsilon subdivisions,2WMZE@28221|Deltaproteobacteria,43UMJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
REGS1_k127_8295281_0	1116472.MGMO_10c00150	8.744e-115	375.0	COG1718@1|root,COG1718@2|Bacteria,1MXY2@1224|Proteobacteria,1RND1@1236|Gammaproteobacteria,1XEAZ@135618|Methylococcales	135618|Methylococcales	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
REGS1_k127_8295281_1	243231.GSU1643	1.09e-99	336.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,43BSG@68525|delta/epsilon subdivisions,2WN9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,Response_reg
REGS1_k127_8304115_0	443143.GM18_4011	2.288e-244	773.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria,43T72@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	ATP-binding region, ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_8304115_2	443143.GM18_4010	8.59e-136	441.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42QZV@68525|delta/epsilon subdivisions,2WN5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
REGS1_k127_8304115_1	443143.GM18_4008	2.517e-181	579.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42R7Z@68525|delta/epsilon subdivisions,2WN0B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
REGS1_k127_8304115_6	289376.THEYE_A0182	1.23e-33	135.0	COG0745@1|root,COG0745@2|Bacteria	289376.THEYE_A0182|-	T	phosphorelay signal transduction system	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
REGS1_k127_8304115_4	443143.GM18_4006	4.276e-43	160.0	COG0745@1|root,COG0745@2|Bacteria	443143.GM18_4006|-	T	phosphorelay signal transduction system	-	-	-	ko:K11443	ko02020,ko04112,map02020,map04112	M00511	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	-
REGS1_k127_8304115_3	269799.Gmet_0714	8.792e-115	377.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,42R10@68525|delta/epsilon subdivisions,2WN3Z@28221|Deltaproteobacteria,43TTH@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
REGS1_k127_8304115_5	1232437.KL662020_gene715	3.769e-34	142.0	COG4585@1|root,COG4585@2|Bacteria,1MWPN@1224|Proteobacteria,42SJA@68525|delta/epsilon subdivisions,2WPP4@28221|Deltaproteobacteria,2MK2H@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,PAS,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_8316436_0	269799.Gmet_0083	0.0	1478.0	COG0330@1|root,COG0330@2|Bacteria,1MW1D@1224|Proteobacteria,42PKQ@68525|delta/epsilon subdivisions,2WM5Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_8316436_3	443144.GM21_1604	5.261e-244	762.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,42KZU@68525|delta/epsilon subdivisions,2WJ6T@28221|Deltaproteobacteria,43UJZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	TIGRFAM drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
REGS1_k127_8316436_6	243231.GSU1481	4.426e-135	440.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42NIC@68525|delta/epsilon subdivisions,2WKV5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_8316436_8	395961.Cyan7425_3699	2.158e-112	391.0	COG0642@1|root,COG0745@1|root,COG5000@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1G13T@1117|Cyanobacteria,3KG2A@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,HATPase_c,HisKA,Response_reg,dCache_1
REGS1_k127_8316436_4	316067.Geob_0285	4.923e-220	695.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,42PGV@68525|delta/epsilon subdivisions,2WIS0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Amidohydrolase family	-	-	3.5.1.81	ko:K06015	-	-	R02192	RC00064,RC00328	ko00000,ko01000	-	-	-	Amidohydro_3
REGS1_k127_8316436_5	316067.Geob_0286	2.298e-212	667.0	COG2610@1|root,COG2610@2|Bacteria,1QYB0@1224|Proteobacteria	1224|Proteobacteria	EG	gluconate transmembrane transporter activity	gntT	-	-	-	-	-	-	-	-	-	-	-	DctM,Na_H_antiporter
REGS1_k127_8316436_18	521011.Mpal_2247	6.067e-30	122.0	COG0784@1|root,arCOG02391@2157|Archaea	2157|Archaea	T	response regulator, receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
REGS1_k127_8316436_17	1232410.KI421428_gene1117	2.302e-58	208.0	COG1776@1|root,COG1776@2|Bacteria,1R430@1224|Proteobacteria,42UXZ@68525|delta/epsilon subdivisions,2X5R0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	CheC-like family	-	-	-	-	-	-	-	-	-	-	-	-	CheC
REGS1_k127_8316436_10	1232410.KI421428_gene1116	2.014e-109	364.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42S7I@68525|delta/epsilon subdivisions,2X7RP@28221|Deltaproteobacteria,43UXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4
REGS1_k127_8316436_11	715451.ambt_08645	2.011e-96	326.0	2F08N@1|root,33TC0@2|Bacteria,1NR97@1224|Proteobacteria,1SK8V@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8316436_20	1120965.AUBV01000007_gene2425	1.837e-13	73.0	COG0732@1|root,COG1002@1|root,COG0732@2|Bacteria,COG1002@2|Bacteria,4NEHR@976|Bacteroidetes,47M22@768503|Cytophagia	976|Bacteroidetes	L	PFAM Eco57I restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I,TaqI_C
REGS1_k127_8316436_19	243231.GSU1358	9.978e-16	77.0	COG0507@1|root,COG1974@1|root,COG3410@1|root,COG0507@2|Bacteria,COG1974@2|Bacteria,COG3410@2|Bacteria,1R703@1224|Proteobacteria,42RBD@68525|delta/epsilon subdivisions,2WUMB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
REGS1_k127_8316436_1	243231.GSU1358	0.0	1302.0	COG0507@1|root,COG1974@1|root,COG3410@1|root,COG0507@2|Bacteria,COG1974@2|Bacteria,COG3410@2|Bacteria,1R703@1224|Proteobacteria,42RBD@68525|delta/epsilon subdivisions,2WUMB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075
REGS1_k127_8316436_13	278957.ABEA03000106_gene1853	1.457e-84	285.0	COG0551@1|root,COG0551@2|Bacteria,46YKN@74201|Verrucomicrobia,3K9SK@414999|Opitutae	414999|Opitutae	L	23S rRNA-intervening sequence protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8316436_15	443143.GM18_3164	4.977e-70	245.0	COG3577@1|root,COG3577@2|Bacteria,1RIR3@1224|Proteobacteria,42UXY@68525|delta/epsilon subdivisions,2WR2W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	gag-polyprotein putative aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2,DUF4124,gag-asp_proteas
REGS1_k127_8316436_2	316067.Geob_2149	2.88e-293	904.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42N1K@68525|delta/epsilon subdivisions,2WIT6@28221|Deltaproteobacteria,43T7U@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
REGS1_k127_8316436_7	269799.Gmet_2320	2.22e-113	374.0	COG1774@1|root,COG1774@2|Bacteria,1MZBX@1224|Proteobacteria,42NE3@68525|delta/epsilon subdivisions,2WK98@28221|Deltaproteobacteria,43TAA@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	PFAM PSP1 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PSP1
REGS1_k127_8316436_12	443143.GM18_3247	4.515e-95	323.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,43UA3@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA polymerase III, delta subunit, C terminal	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
REGS1_k127_8316436_14	269799.Gmet_2318	2.725e-83	281.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,43U3M@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
REGS1_k127_8316436_16	443143.GM18_3206	4.746e-67	235.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,43SGK@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
REGS1_k127_8316436_9	269799.Gmet_2316	1.482e-111	372.0	COG1243@1|root,COG1243@2|Bacteria,1MUYS@1224|Proteobacteria,42N2I@68525|delta/epsilon subdivisions,2WKZX@28221|Deltaproteobacteria,43TDM@69541|Desulfuromonadales	28221|Deltaproteobacteria	BK	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM,Radical_SAM_C
REGS1_k127_8318318_5	316067.Geob_1834	4.711e-94	321.0	COG3880@1|root,COG3880@2|Bacteria	2|Bacteria	E	PFAM UvrB UvrC protein	mcsA	GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170	2.7.14.1	ko:K08999,ko:K19405,ko:K19411	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	Cytochrom_CIII,Cytochrome_C7,UVR
REGS1_k127_8318318_4	269799.Gmet_0591	7.941e-117	401.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_35,CBM_6,He_PIG,Malectin
REGS1_k127_8318318_10	243231.GSU2909	8.62e-55	197.0	COG1732@1|root,COG1732@2|Bacteria	2|Bacteria	M	glycine betaine transport	yehZ	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
REGS1_k127_8318318_3	269799.Gmet_0568	2.653e-146	467.0	COG3221@1|root,COG3221@2|Bacteria,1NPBT@1224|Proteobacteria,42NX8@68525|delta/epsilon subdivisions,2X5DW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
REGS1_k127_8318318_7	269799.Gmet_0494	4.704e-65	224.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,42SID@68525|delta/epsilon subdivisions,2WQ86@28221|Deltaproteobacteria,43SGS@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	nickel-responsive regulator	nikR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
REGS1_k127_8318318_0	269799.Gmet_0559	3.411e-261	829.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD
REGS1_k127_8318318_11	316067.Geob_3355	2.346e-46	173.0	COG1732@1|root,COG1732@2|Bacteria	2|Bacteria	M	glycine betaine transport	yehZ	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
REGS1_k127_8318318_1	269799.Gmet_0563	1.343e-227	722.0	COG0701@1|root,COG0701@2|Bacteria	2|Bacteria	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
REGS1_k127_8318318_12	243231.GSU2906	7.959e-44	162.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_8318318_2	269799.Gmet_0566	9.996e-149	477.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
REGS1_k127_8318318_8	269799.Gmet_0567	5.334e-61	222.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,PS_pyruv_trans,Radical_SAM,SPASM
REGS1_k127_8318318_17	316067.Geob_1967	1.735e-21	108.0	COG1404@1|root,COG2911@1|root,COG3055@1|root,COG1404@2|Bacteria,COG2911@2|Bacteria,COG3055@2|Bacteria,1QXZF@1224|Proteobacteria	1224|Proteobacteria	M	family outer membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3739,ESPR,Haemagg_act
REGS1_k127_8404491_0	243231.GSU3357	3.397e-119	403.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9
REGS1_k127_8404491_1	269799.Gmet_3236	1.615e-59	216.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,42PBB@68525|delta/epsilon subdivisions,2WKBZ@28221|Deltaproteobacteria,43UU7@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM hydrolase, TatD family	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
REGS1_k127_8406420_7	316067.Geob_1282	3.361e-63	221.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,42UGR@68525|delta/epsilon subdivisions,2WR3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
REGS1_k127_8406420_5	316067.Geob_1281	6.75e-77	260.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,42UGR@68525|delta/epsilon subdivisions,2WR3D@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	S	phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
REGS1_k127_8406420_2	316067.Geob_1280	3.051e-92	304.0	COG4675@1|root,COG4675@2|Bacteria,1MZY9@1224|Proteobacteria,42UGR@68525|delta/epsilon subdivisions,2WR3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
REGS1_k127_8406420_8	316067.Geob_1279	1.495e-35	138.0	2DFNT@1|root,2ZSHD@2|Bacteria,1P70B@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8406420_6	316067.Geob_1278	6.477e-68	235.0	COG0454@1|root,COG0456@2|Bacteria,1N29T@1224|Proteobacteria,42VMN@68525|delta/epsilon subdivisions,2WRZ8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
REGS1_k127_8406420_4	338966.Ppro_0051	4.861e-77	269.0	COG0421@1|root,COG0421@2|Bacteria,1RJQS@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8406420_3	243231.GSU1918	5.251e-79	267.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,43UDS@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
REGS1_k127_8406420_0	316067.Geob_1520	5.957e-124	400.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,43SW0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
REGS1_k127_8406420_1	398767.Glov_2709	8.449e-118	385.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,43S6V@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
REGS1_k127_8412726_2	243231.GSU0076	1.249e-11	68.0	2EIFC@1|root,33C6Q@2|Bacteria,1NX12@1224|Proteobacteria,43080@68525|delta/epsilon subdivisions,2WVC5@28221|Deltaproteobacteria,43V28@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8412726_0	398767.Glov_0101	5.451e-157	499.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,42N8V@68525|delta/epsilon subdivisions,2WJWB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
REGS1_k127_8412726_1	443143.GM18_0495	3.264e-43	160.0	2E8BS@1|root,332QF@2|Bacteria,1R3CW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8459101_31	243231.GSU1101	6.241e-48	175.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,42NB5@68525|delta/epsilon subdivisions,2WJGX@28221|Deltaproteobacteria,43TY2@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Phosphate sensor histidine kinase, HAMP and PAS domain-containing	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_8,sCache_like
REGS1_k127_8459101_36	243231.GSU2929	2.138e-40	154.0	COG2703@1|root,COG2703@2|Bacteria,1N8CS@1224|Proteobacteria,42VDH@68525|delta/epsilon subdivisions,2WRTV@28221|Deltaproteobacteria,43VEP@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_8459101_4	443143.GM18_1307	8.622e-184	579.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,42NM3@68525|delta/epsilon subdivisions,2WMH9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_8459101_8	316067.Geob_2011	9.626e-144	461.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WK67@28221|Deltaproteobacteria,43VF5@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	iAF987.Gmet_2702	BPD_transp_1
REGS1_k127_8459101_10	269799.Gmet_2703	1.433e-131	424.0	COG0581@1|root,COG0581@2|Bacteria,1MUWB@1224|Proteobacteria,42MWK@68525|delta/epsilon subdivisions,2WMUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM phosphate ABC transporter	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
REGS1_k127_8459101_9	443144.GM21_2505	1.867e-133	428.0	COG1117@1|root,COG1117@2|Bacteria,1MU16@1224|Proteobacteria,42MWA@68525|delta/epsilon subdivisions,2WJEX@28221|Deltaproteobacteria,43U4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
REGS1_k127_8459101_15	443143.GM18_1519	1.419e-107	351.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WMS0@28221|Deltaproteobacteria,43TYN@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
REGS1_k127_8459101_35	404380.Gbem_0338	7.752e-42	160.0	COG2133@1|root,COG2133@2|Bacteria,1PUU2@1224|Proteobacteria,433G4@68525|delta/epsilon subdivisions,2WXG5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
REGS1_k127_8459101_0	398767.Glov_3011	2.663e-321	988.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,43T6U@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_8459101_29	269799.Gmet_0145	2.168e-52	186.0	COG1872@1|root,COG1872@2|Bacteria,1QR2V@1224|Proteobacteria,42TX9@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
REGS1_k127_8459101_40	398767.Glov_3027	1.422e-30	123.0	COG4728@1|root,COG4728@2|Bacteria,1N6NP@1224|Proteobacteria,42WCY@68525|delta/epsilon subdivisions,2WRUU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
REGS1_k127_8459101_12	243231.GSU0116	7.274e-113	371.0	COG0744@1|root,COG0744@2|Bacteria,1RB3Z@1224|Proteobacteria,43B0J@68525|delta/epsilon subdivisions,2WN47@28221|Deltaproteobacteria,43SG0@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
REGS1_k127_8459101_25	269799.Gmet_2626	7.64e-65	226.0	2DKVG@1|root,30GRY@2|Bacteria,1RDQT@1224|Proteobacteria,42V8G@68525|delta/epsilon subdivisions,2WRP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cytochrome P460	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_P460
REGS1_k127_8459101_13	1472716.KBK24_0112070	3.596e-110	360.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,2VKUH@28216|Betaproteobacteria,1K23D@119060|Burkholderiaceae	28216|Betaproteobacteria	S	PFAM ThiJ PfpI domain protein	nonF	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
REGS1_k127_8459101_24	1232410.KI421418_gene2357	2.666e-65	254.0	COG4932@1|root,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,42RZP@68525|delta/epsilon subdivisions,2X7KQ@28221|Deltaproteobacteria,43SHG@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8459101_48	1121935.AQXX01000091_gene3819	3.062e-13	84.0	COG0823@1|root,COG3420@1|root,COG4932@1|root,COG0823@2|Bacteria,COG3420@2|Bacteria,COG4932@2|Bacteria,1NGRY@1224|Proteobacteria,1T22S@1236|Gammaproteobacteria,1XS0U@135619|Oceanospirillales	135619|Oceanospirillales	P	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
REGS1_k127_8459101_46	351160.RCIX1696	7.109e-16	93.0	arCOG03561@1|root,arCOG03561@2157|Archaea	2157|Archaea	G	PFAM NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8459101_50	36630.CADNFIAP00008520	0.0004857	43.0	COG0484@1|root,KOG0712@2759|Eukaryota,38GG3@33154|Opisthokonta,3NU15@4751|Fungi,3QJJ1@4890|Ascomycota,20C0Z@147545|Eurotiomycetes,3S341@5042|Eurotiales	4751|Fungi	O	DnaJ domain protein	SCJ1	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006986,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0019538,GO:0019941,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031974,GO:0033554,GO:0034620,GO:0034975,GO:0034976,GO:0035966,GO:0035967,GO:0036503,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051087,GO:0051603,GO:0051716,GO:0070013,GO:0070887,GO:0071310,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901698	-	ko:K14002	ko04141,map04141	-	-	-	ko00000,ko00001	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
REGS1_k127_8459101_18	1232410.KI421424_gene1840	9.406e-106	347.0	COG0500@1|root,COG2226@2|Bacteria,1R5UA@1224|Proteobacteria,42P7B@68525|delta/epsilon subdivisions,2WJSN@28221|Deltaproteobacteria,43SXN@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
REGS1_k127_8459101_28	316067.Geob_1159	9.115e-54	192.0	COG0662@1|root,COG0662@2|Bacteria,1N3UA@1224|Proteobacteria,42U03@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_8459101_30	690850.Desaf_2565	7.506e-51	187.0	2BIF3@1|root,32CMK@2|Bacteria,1PZIU@1224|Proteobacteria,43602@68525|delta/epsilon subdivisions,2X0HK@28221|Deltaproteobacteria,2MCCC@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
REGS1_k127_8459101_47	398767.Glov_3572	1.382e-14	75.0	COG1487@1|root,COG1487@2|Bacteria,1N44Q@1224|Proteobacteria,42UNG@68525|delta/epsilon subdivisions,2WRVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
REGS1_k127_8459101_3	443144.GM21_1994	1.16e-200	637.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WN60@28221|Deltaproteobacteria,43UE3@69541|Desulfuromonadales	28221|Deltaproteobacteria	FP	metal-dependent phosphohydrolase, HD sub domain	gppA-2	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
REGS1_k127_8459101_32	243231.GSU2560	5.639e-45	179.0	COG5607@1|root,COG5607@2|Bacteria,1NGVB@1224|Proteobacteria,42X7Z@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM CHAD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
REGS1_k127_8459101_20	497964.CfE428DRAFT_6353	6.669e-89	298.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.4.9,4.1.1.19	ko:K00943,ko:K01585	ko00240,ko00330,ko01100,map00240,map00330,map01100	M00053,M00133	R00566,R02094,R02098	RC00002,RC00299	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
REGS1_k127_8459101_19	497964.CfE428DRAFT_6354	6.814e-102	339.0	COG0125@1|root,COG0125@2|Bacteria	2|Bacteria	F	dTDP biosynthetic process	tmk	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.1.1.45,2.7.4.9,4.1.1.19	ko:K00560,ko:K00943,ko:K01585	ko00240,ko00330,ko00670,ko01100,ko01523,map00240,map00330,map00670,map01100,map01523	M00053,M00133	R00566,R02094,R02098,R02101	RC00002,RC00219,RC00299,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS00680,iJN746.PP_3363,iNJ661.Rv3247c	AAA_33,Thymidylate_kin
REGS1_k127_8459101_37	443143.GM18_1996	5.959e-38	148.0	COG2062@1|root,COG2062@2|Bacteria,1NH0V@1224|Proteobacteria,42WVA@68525|delta/epsilon subdivisions,2WT6K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM Phosphoglycerate mutase	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
REGS1_k127_8459101_42	243231.GSU1308	5.214e-22	96.0	2EPGU@1|root,33H3E@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1450)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1450
REGS1_k127_8459101_2	398767.Glov_3059	1.443e-235	737.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,42M26@68525|delta/epsilon subdivisions,2WKQV@28221|Deltaproteobacteria,43V5R@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
REGS1_k127_8459101_5	159087.Daro_3904	6.013e-180	588.0	COG0659@1|root,COG0664@1|root,COG0659@2|Bacteria,COG0664@2|Bacteria,1MVWV@1224|Proteobacteria,2VN25@28216|Betaproteobacteria,2KXUF@206389|Rhodocyclales	206389|Rhodocyclales	P	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp,cNMP_binding
REGS1_k127_8459101_38	768706.Desor_5227	1.417e-37	149.0	COG1392@1|root,COG1392@2|Bacteria,1UYRI@1239|Firmicutes,24BCU@186801|Clostridia,261YI@186807|Peptococcaceae	186801|Clostridia	P	phosphate transport regulator	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
REGS1_k127_8459101_7	316067.Geob_0605	1.754e-172	545.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42Q5K@68525|delta/epsilon subdivisions,2X5HI@28221|Deltaproteobacteria,43UF4@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PFAM phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
REGS1_k127_8459101_17	269799.Gmet_3377	1.447e-106	355.0	COG1397@1|root,COG1397@2|Bacteria,1RA82@1224|Proteobacteria,42QPD@68525|delta/epsilon subdivisions,2WMNN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
REGS1_k127_8459101_39	439235.Dalk_0327	4.179e-35	145.0	arCOG05209@1|root,31PIN@2|Bacteria,1P3KH@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8459101_1	1232410.KI421412_gene16	3.252e-278	909.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,43SUV@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
REGS1_k127_8459101_11	411902.CLOBOL_04226	4.72e-118	427.0	COG0574@1|root,COG0574@2|Bacteria,1TW0W@1239|Firmicutes,248VM@186801|Clostridia,21XJD@1506553|Lachnoclostridium	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
REGS1_k127_8459101_23	316067.Geob_3806	2.78e-69	243.0	COG1333@1|root,COG1333@2|Bacteria,1RIJF@1224|Proteobacteria,42T2N@68525|delta/epsilon subdivisions,2WPA1@28221|Deltaproteobacteria,43VTI@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	cytochrome c biogenesis protein	-	-	-	-	-	-	-	-	-	-	-	-	ResB
REGS1_k127_8459101_14	269799.Gmet_0141	1.561e-108	357.0	COG0755@1|root,COG0755@2|Bacteria	2|Bacteria	O	cytochrome complex assembly	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_8459101_16	316067.Geob_3172	7.56e-107	353.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42P5W@68525|delta/epsilon subdivisions,2WMA6@28221|Deltaproteobacteria,43SFK@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_8459101_34	316067.Geob_3173	5.834e-42	158.0	COG1664@1|root,COG1664@2|Bacteria,1MZG6@1224|Proteobacteria	1224|Proteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	WS1240	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_8459101_33	243231.GSU0224	9.66e-43	159.0	COG1917@1|root,COG1917@2|Bacteria,1RJX2@1224|Proteobacteria,42TVK@68525|delta/epsilon subdivisions,2WQ2T@28221|Deltaproteobacteria,43SQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_8459101_22	243231.GSU0233	4.781e-77	267.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,42S8C@68525|delta/epsilon subdivisions,2WP10@28221|Deltaproteobacteria,43TU3@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF480	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
REGS1_k127_8459101_27	1232410.KI421421_gene3487	9.625e-56	198.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,42MCS@68525|delta/epsilon subdivisions,2WV5U@28221|Deltaproteobacteria,43UX5@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	FKBP-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	FKBP_C
REGS1_k127_8459101_41	1232410.KI421412_gene82	6.937e-23	102.0	COG2026@1|root,COG2026@2|Bacteria,1NP1I@1224|Proteobacteria,437H9@68525|delta/epsilon subdivisions,2WVKQ@28221|Deltaproteobacteria,43V3Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_8459101_44	443143.GM18_2856	6.561e-18	85.0	2CBYU@1|root,334FI@2|Bacteria,1NC3J@1224|Proteobacteria,42VH4@68525|delta/epsilon subdivisions,2WSCN@28221|Deltaproteobacteria,43STQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
REGS1_k127_8459101_6	269799.Gmet_0257	1.076e-179	572.0	COG2271@1|root,COG2271@2|Bacteria,1PND6@1224|Proteobacteria,42RJK@68525|delta/epsilon subdivisions,2WNEM@28221|Deltaproteobacteria,43UWP@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_8459101_21	398767.Glov_2959	2.457e-83	279.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
REGS1_k127_8459101_26	316067.Geob_0260	2.372e-56	199.0	COG2414@1|root,COG2414@2|Bacteria,1R76Y@1224|Proteobacteria,42QE3@68525|delta/epsilon subdivisions,2WIIW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Aldehyde ferredoxin oxidoreductase, N-terminal domain	-	-	1.2.7.5	ko:K03738	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00309	R08571	RC00242	ko00000,ko00001,ko00002,ko01000	-	-	-	AFOR_C,AFOR_N
REGS1_k127_8505742_5	316067.Geob_2595	2.872e-46	171.0	COG1309@1|root,COG1309@2|Bacteria,1NI5D@1224|Proteobacteria,42XAH@68525|delta/epsilon subdivisions,2WSYM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
REGS1_k127_8505742_1	316067.Geob_2594	0.0	1002.0	COG0427@1|root,COG0427@2|Bacteria,1MUGE@1224|Proteobacteria,42MB6@68525|delta/epsilon subdivisions,2WJMI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Acetyl-CoA hydrolase transferase	ato-2	-	2.8.3.18,3.1.2.1	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	M00009,M00011	R00227,R10343	RC00004,RC00012,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
REGS1_k127_8505742_7	1232410.KI421421_gene3497	4.933e-13	70.0	2DH0C@1|root,2ZXY2@2|Bacteria,1P8UR@1224|Proteobacteria,4333M@68525|delta/epsilon subdivisions,2WYH7@28221|Deltaproteobacteria,43VRE@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8505742_9	316067.Geob_1596	1.315e-07	56.0	2DE5A@1|root,2ZKJI@2|Bacteria,1PAS5@1224|Proteobacteria,4332P@68525|delta/epsilon subdivisions,2WXBB@28221|Deltaproteobacteria,43VQK@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8505742_4	316067.Geob_1597	7.812e-48	175.0	COG2204@1|root,COG2204@2|Bacteria,1NVZB@1224|Proteobacteria,43031@68525|delta/epsilon subdivisions,2WVIP@28221|Deltaproteobacteria,43UW8@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_8505742_2	316067.Geob_2092	3.773e-115	378.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,42T82@68525|delta/epsilon subdivisions,2WTPA@28221|Deltaproteobacteria,43T0I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	TraB family	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
REGS1_k127_8505742_3	269799.Gmet_2811	6.944e-104	366.0	COG2770@1|root,COG4251@1|root,COG2770@2|Bacteria,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,42QPS@68525|delta/epsilon subdivisions,2WMWT@28221|Deltaproteobacteria,43T94@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase, Cache_1, HAMP and PAS domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,PAS,PAS_4,PAS_8,PAS_9,dCache_1
REGS1_k127_8505742_6	269799.Gmet_0152	8.123e-46	169.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42U92@68525|delta/epsilon subdivisions,2WQCK@28221|Deltaproteobacteria,43SNY@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
REGS1_k127_8505742_0	316067.Geob_1263	0.0	1122.0	COG0377@1|root,COG0649@1|root,COG0852@1|root,COG0377@2|Bacteria,COG0649@2|Bacteria,COG0852@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,43S0B@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoBCD	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00333,ko:K13378,ko:K13380	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,Oxidored_q6
REGS1_k127_8551440_1	269799.Gmet_0812	5.534e-101	333.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UD9@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_8551440_0	243231.GSU2430	8.696e-116	381.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,42NX0@68525|delta/epsilon subdivisions,2WISZ@28221|Deltaproteobacteria,43S6P@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_8551440_3	398767.Glov_1897	2.356e-40	154.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
REGS1_k127_8551440_2	316067.Geob_3496	2.051e-54	194.0	COG1528@1|root,COG1528@2|Bacteria,1R9ZC@1224|Proteobacteria,42S74@68525|delta/epsilon subdivisions,2WNFJ@28221|Deltaproteobacteria,43UMB@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Iron-storage protein	ftn	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
REGS1_k127_8575140_7	338966.Ppro_1333	1.471e-32	133.0	COG0582@1|root,COG0582@2|Bacteria,1REKP@1224|Proteobacteria,42S9N@68525|delta/epsilon subdivisions,2WNI9@28221|Deltaproteobacteria,43UXW@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
REGS1_k127_8575140_8	243231.GSU1627	1.711e-27	115.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,43V72@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
REGS1_k127_8575140_5	243231.GSU3627	6.22e-111	363.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,42MIF@68525|delta/epsilon subdivisions,2WIQF@28221|Deltaproteobacteria,43T81@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
REGS1_k127_8575140_2	398767.Glov_1617	1.293e-237	739.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,43UJK@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
REGS1_k127_8575140_3	269799.Gmet_1946	1.117e-182	575.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,43S9H@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
REGS1_k127_8575140_6	316067.Geob_2895	2.762e-106	350.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,42NE6@68525|delta/epsilon subdivisions,2WJ92@28221|Deltaproteobacteria,43TQ8@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
REGS1_k127_8575140_0	398767.Glov_2695	5.371e-252	780.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,43TS7@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
REGS1_k127_8575140_4	243231.GSU1633	2.364e-143	463.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,42NUP@68525|delta/epsilon subdivisions,2WKSD@28221|Deltaproteobacteria,43U9T@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM MscS Mechanosensitive ion channel	mscS-1	-	-	ko:K16052	-	-	-	-	ko00000,ko02000	1.A.23.4	-	-	MS_channel
REGS1_k127_8575140_1	338966.Ppro_1147	4.883e-244	761.0	COG0046@1|root,COG1828@1|root,COG0046@2|Bacteria,COG1828@2|Bacteria,1MYN4@1224|Proteobacteria,42M08@68525|delta/epsilon subdivisions,2WITS@28221|Deltaproteobacteria,43TKA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,PurS
REGS1_k127_8577840_3	1121918.ARWE01000001_gene1622	8.739e-154	494.0	COG2199@1|root,COG3829@1|root,COG4191@1|root,COG2199@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	4.6.1.2	ko:K01769,ko:K11959	ko00230,ko02010,map00230,map02010	M00323	R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	GAF_2,GGDEF,HATPase_c,HTH_8,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
REGS1_k127_8577840_0	1121918.ARWE01000001_gene1621	1.015e-268	835.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,43S4A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH
REGS1_k127_8577840_1	443143.GM18_3979	5.884e-201	631.0	COG2230@1|root,COG2230@2|Bacteria,1R9QV@1224|Proteobacteria,42Z7M@68525|delta/epsilon subdivisions,2WU14@28221|Deltaproteobacteria,43TN2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
REGS1_k127_8577840_2	443144.GM21_3706	5.397e-191	609.0	COG3459@1|root,COG3459@2|Bacteria,1MVNX@1224|Proteobacteria,42PFN@68525|delta/epsilon subdivisions,2WJVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	glycosyltransferase 36 associated	-	-	2.4.1.20	ko:K00702,ko:K13688	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000,ko01003	-	GH94,GT36,GT84	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
REGS1_k127_8633998_7	316067.Geob_1009	2.387e-176	557.0	COG1085@1|root,COG1085@2|Bacteria,1MU3E@1224|Proteobacteria,42MP4@68525|delta/epsilon subdivisions,2WKT8@28221|Deltaproteobacteria,43S3R@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Galactose-1-phosphate uridyl transferase, N-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF4921,GalP_UDP_tr_C,GalP_UDP_transf
REGS1_k127_8633998_2	316067.Geob_1008	3.863e-294	919.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,42N8E@68525|delta/epsilon subdivisions,2WIY0@28221|Deltaproteobacteria,43UIP@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
REGS1_k127_8633998_0	243231.GSU3254	0.0	1258.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,1MUYJ@1224|Proteobacteria,42MX5@68525|delta/epsilon subdivisions,2WKAF@28221|Deltaproteobacteria,43TN9@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	phosphoglucomutase phosphomannomutase alpha beta alpha domain I	-	-	2.7.7.13,5.4.2.8	ko:K00966,ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00361,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3178	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
REGS1_k127_8633998_12	398767.Glov_0406	1.699e-45	170.0	COG0784@1|root,COG0784@2|Bacteria,1N017@1224|Proteobacteria,42UW8@68525|delta/epsilon subdivisions,2X7PA@28221|Deltaproteobacteria,43W1W@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_8633998_5	443144.GM21_3467	6.225e-186	596.0	COG0642@1|root,COG2205@2|Bacteria,1R6JD@1224|Proteobacteria,42PHF@68525|delta/epsilon subdivisions,2WMI6@28221|Deltaproteobacteria,43S07@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA
REGS1_k127_8633998_13	443143.GM18_2198	7.061e-45	169.0	COG4957@1|root,COG4957@2|Bacteria,1RGUW@1224|Proteobacteria,42VJM@68525|delta/epsilon subdivisions,2WRBG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	PFAM ROSMUCR transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	ROS_MUCR
REGS1_k127_8633998_6	269799.Gmet_0699	9.733e-182	574.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,43TA4@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metC-2	-	4.4.1.8	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_8633998_4	243231.GSU0944	7.095e-192	605.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,43SWV@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent	metC-1	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_8633998_8	269799.Gmet_3449	6.328e-95	316.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,42T4I@68525|delta/epsilon subdivisions,2WPAC@28221|Deltaproteobacteria,43UU5@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
REGS1_k127_8633998_1	338966.Ppro_3702	0.0	996.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,42M2C@68525|delta/epsilon subdivisions,2WIVE@28221|Deltaproteobacteria,43T34@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_2834	Prismane
REGS1_k127_8633998_9	316067.Geob_2205	7.79e-82	278.0	2E16P@1|root,32WMF@2|Bacteria,1N22X@1224|Proteobacteria,42TQ1@68525|delta/epsilon subdivisions,2WQTH@28221|Deltaproteobacteria,43VB5@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8633998_14	935948.KE386495_gene1560	5.744e-25	106.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,42H59@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rd	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592	1.18.1.1	ko:K05297	ko00071,map00071	-	R02000	-	ko00000,ko00001,ko01000	-	-	-	Rubredoxin
REGS1_k127_8633998_3	243231.GSU0843	8.249e-223	696.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,42N3G@68525|delta/epsilon subdivisions,2WIS9@28221|Deltaproteobacteria,43TPE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_8633998_11	269799.Gmet_3491	4.925e-71	250.0	COG5483@1|root,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,42WDP@68525|delta/epsilon subdivisions,2WRK2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
REGS1_k127_8633998_10	398767.Glov_0214	3.526e-73	248.0	COG5002@1|root,COG5002@2|Bacteria,1RI2X@1224|Proteobacteria,43CGW@68525|delta/epsilon subdivisions,2X7S2@28221|Deltaproteobacteria,43VYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	SMART PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	PAS_4
REGS1_k127_8866775_46	338966.Ppro_2335	1.253e-29	123.0	COG1943@1|root,COG1943@2|Bacteria,1RIWM@1224|Proteobacteria,42SBY@68525|delta/epsilon subdivisions,2WPSK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
REGS1_k127_8866775_36	1449126.JQKL01000008_gene230	4.556e-62	218.0	COG0778@1|root,COG0778@2|Bacteria,1V0Y6@1239|Firmicutes,24HMV@186801|Clostridia,269WT@186813|unclassified Clostridiales	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
REGS1_k127_8866775_26	398767.Glov_1232	1.939e-101	333.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria	1224|Proteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
REGS1_k127_8866775_49	243231.GSU2743	7.033e-26	109.0	COG2010@1|root,COG2010@2|Bacteria,1P1Y0@1224|Proteobacteria,43213@68525|delta/epsilon subdivisions,2WWTT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08906	ko00195,map00195	-	-	-	ko00000,ko00001,ko00194	-	-	-	Cytochrome_CBB3
REGS1_k127_8866775_44	1382304.JNIL01000001_gene1536	8.641e-36	149.0	COG0109@1|root,COG0109@2|Bacteria,1TPS1@1239|Firmicutes,4HFHQ@91061|Bacilli	91061|Bacilli	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
REGS1_k127_8866775_16	269799.Gmet_0252	1.617e-137	446.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,1MWHZ@1224|Proteobacteria,42M7N@68525|delta/epsilon subdivisions,2WM4F@28221|Deltaproteobacteria,43T32@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	coxB	-	1.10.3.10,1.9.3.1	ko:K02275,ko:K02297	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX2,COX2_TM,COX_ARM,Cytochrom_C,Cytochrome_CBB3
REGS1_k127_8866775_39	290317.Cpha266_1617	1.237e-45	173.0	COG1573@1|root,COG1573@2|Bacteria	2|Bacteria	L	deaminated base DNA N-glycosylase activity	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_8866775_53	1033810.HLPCO_002146	8.977e-07	53.0	2AHWM@1|root,3189H@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8866775_28	269799.Gmet_0250	8.856e-89	313.0	COG1845@1|root,COG1845@2|Bacteria,1MUCK@1224|Proteobacteria,42RCU@68525|delta/epsilon subdivisions,2WMXY@28221|Deltaproteobacteria,43SI0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c oxidase subunit III	coxC	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
REGS1_k127_8866775_1	269799.Gmet_0249	3.817e-311	960.0	COG0843@1|root,COG0843@2|Bacteria,1MU7S@1224|Proteobacteria,42M18@68525|delta/epsilon subdivisions,2WJUK@28221|Deltaproteobacteria,43S0R@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	coxA	-	1.10.3.10,1.9.3.1	ko:K02274,ko:K02298	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081,R11335	RC00016,RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX1
REGS1_k127_8866775_21	269799.Gmet_0248	2.351e-115	377.0	COG1999@1|root,COG1999@2|Bacteria,1R9EM@1224|Proteobacteria,42N5F@68525|delta/epsilon subdivisions,2WKG7@28221|Deltaproteobacteria,43RX9@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems	sco	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	-
REGS1_k127_8866775_27	404380.Gbem_1086	4.1e-97	325.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	-	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Cytochrom_c3_2,Cytochrome_C554,Ni_hydr_CYTB
REGS1_k127_8866775_7	243231.GSU1649	5.091e-185	583.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,42MD6@68525|delta/epsilon subdivisions,2WPA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	cbcW	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrom_C,Cytochrome_B,Cytochrome_CBB3
REGS1_k127_8866775_38	443143.GM18_0922	7.315e-55	196.0	COG0723@1|root,COG0723@2|Bacteria,1NINP@1224|Proteobacteria,42X9Z@68525|delta/epsilon subdivisions,2WSPW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Rieske 2Fe-2S	cbcV	-	1.10.9.1	ko:K02636	ko00195,ko01100,map00195,map01100	M00162	R03817,R08409	RC01002	ko00000,ko00001,ko00002,ko00194,ko01000	-	-	iAF987.Gmet_1922	CytB6-F_Fe-S,Rieske
REGS1_k127_8866775_0	338966.Ppro_0729	0.0	2368.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,43RZ1@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Glutamate synthase central domain	gltS	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
REGS1_k127_8866775_47	243231.GSU0195	1.569e-29	120.0	COG3360@1|root,COG3360@2|Bacteria,1N6UT@1224|Proteobacteria,42XUW@68525|delta/epsilon subdivisions,2WSV8@28221|Deltaproteobacteria,43VGE@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
REGS1_k127_8866775_34	269799.Gmet_1908	9.658e-76	257.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42SK2@68525|delta/epsilon subdivisions,2WPB3@28221|Deltaproteobacteria,43URW@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
REGS1_k127_8866775_9	316067.Geob_2245	5.045e-179	567.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,42N6F@68525|delta/epsilon subdivisions,2WKX7@28221|Deltaproteobacteria,43UGX@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM 2-nitropropane dioxygenase NPD	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
REGS1_k127_8866775_35	243231.GSU1195	1.254e-66	236.0	COG1418@1|root,COG1418@2|Bacteria,1RK7K@1224|Proteobacteria,42SRK@68525|delta/epsilon subdivisions,2WP5I@28221|Deltaproteobacteria,43UQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Metal-dependent phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HD
REGS1_k127_8866775_10	443144.GM21_2083	3.338e-168	535.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42PDA@68525|delta/epsilon subdivisions,2WKF9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
REGS1_k127_8866775_32	316067.Geob_0431	1.592e-80	275.0	COG0500@1|root,COG2226@2|Bacteria,1RFBE@1224|Proteobacteria,42VEH@68525|delta/epsilon subdivisions,2WVST@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
REGS1_k127_8866775_12	404380.Gbem_3307	9.989e-161	515.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_8866775_24	316067.Geob_0429	6.976e-105	350.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,43AJA@68525|delta/epsilon subdivisions,2X5ZM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_8866775_23	316067.Geob_1222	1.137e-107	370.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_8866775_8	316067.Geob_0428	1.572e-181	581.0	2CCXX@1|root,2Z8MY@2|Bacteria,1RE6D@1224|Proteobacteria,42YFY@68525|delta/epsilon subdivisions,2WUKJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM NDP-hexose 23-dehydratase	-	-	4.2.1.159	ko:K16435	ko00523,ko01055,ko01130,map00523,map01055,map01130	M00798,M00799,M00800,M00801,M00802,M00803	R05518,R06428	RC00782,RC01448	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexose_dehydrat
REGS1_k127_8866775_14	316067.Geob_0427	5.723e-142	457.0	COG0463@1|root,COG0463@2|Bacteria,1RCVF@1224|Proteobacteria,43CNQ@68525|delta/epsilon subdivisions,2WUDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
REGS1_k127_8866775_20	269799.Gmet_1292	8.558e-117	383.0	COG5002@1|root,COG5002@2|Bacteria,1QXNZ@1224|Proteobacteria,43C4T@68525|delta/epsilon subdivisions,2X7F7@28221|Deltaproteobacteria,43T48@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_8866775_18	243231.GSU1879	7.76e-126	405.0	COG0745@1|root,COG0745@2|Bacteria,1N5ZC@1224|Proteobacteria,42NII@68525|delta/epsilon subdivisions,2WJ2Z@28221|Deltaproteobacteria,43UBC@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_8866775_6	316067.Geob_2241	9.927e-209	655.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,43TWM@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
REGS1_k127_8866775_29	398767.Glov_0689	1.803e-82	291.0	COG2885@1|root,COG3047@1|root,COG2885@2|Bacteria,COG3047@2|Bacteria,1P1AB@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	BON,OMP_b-brl,OmpA,OmpA_membrane
REGS1_k127_8866775_3	404380.Gbem_0875	1.675e-241	758.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,43TR7@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
REGS1_k127_8866775_41	316067.Geob_2285	2.868e-44	164.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,42SST@68525|delta/epsilon subdivisions,2WPWN@28221|Deltaproteobacteria,43V5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PTS system fructose IIA component	-	-	2.7.1.191	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	M00276	R02630	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.6.1	-	-	EIIA-man
REGS1_k127_8866775_19	269799.Gmet_1286	4.447e-121	394.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,43U8A@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
REGS1_k127_8866775_11	316067.Geob_2283	2.204e-167	530.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,43TVV@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
REGS1_k127_8866775_42	316067.Geob_2282	9.591e-37	144.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,43SM8@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
REGS1_k127_8866775_33	316067.Geob_2281	3.522e-80	271.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,43TY8@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
REGS1_k127_8866775_5	269799.Gmet_1283	2.01e-218	686.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,43UH4@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
REGS1_k127_8866775_22	316067.Geob_2279	5.004e-112	366.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,43T7P@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_8866775_40	269799.Gmet_1281	3.464e-45	169.0	COG1934@1|root,COG1934@2|Bacteria,1RM28@1224|Proteobacteria,42V9N@68525|delta/epsilon subdivisions,2WRB1@28221|Deltaproteobacteria,43V6Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
REGS1_k127_8866775_48	269799.Gmet_1280	1.007e-26	117.0	COG3117@1|root,COG3117@2|Bacteria,1NJ37@1224|Proteobacteria,42XKQ@68525|delta/epsilon subdivisions,2WSSC@28221|Deltaproteobacteria,43VDN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	-	-	-	-	-	-	-	-	-	LptC,OstA
REGS1_k127_8866775_30	443143.GM18_1427	1.435e-81	274.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,42SN2@68525|delta/epsilon subdivisions,2WPT4@28221|Deltaproteobacteria,43UYH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
REGS1_k127_8866775_13	443143.GM18_1426	3.188e-147	472.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,42M0M@68525|delta/epsilon subdivisions,2WJ4Y@28221|Deltaproteobacteria,43SXB@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iAF987.Gmet_1278	CBS,SIS
REGS1_k127_8866775_15	316067.Geob_2274	3.151e-140	449.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,42M61@68525|delta/epsilon subdivisions,2WIXU@28221|Deltaproteobacteria,43TJ3@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM DAHP synthetase I KDSA	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
REGS1_k127_8866775_37	443143.GM18_1236	3.804e-57	208.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_8866775_4	443143.GM18_4314	5.813e-229	719.0	COG0659@1|root,COG0659@2|Bacteria,1MXA7@1224|Proteobacteria,42ZHY@68525|delta/epsilon subdivisions,2WV08@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
REGS1_k127_8866775_2	269799.Gmet_1276	1.125e-307	947.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,43T0T@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
REGS1_k127_8866775_17	316067.Geob_2272	5.304e-132	424.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,42PTX@68525|delta/epsilon subdivisions,2WMQW@28221|Deltaproteobacteria,43T2I@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
REGS1_k127_8866775_51	1538295.JY96_01095	2.775e-19	100.0	2CKIZ@1|root,341A2@2|Bacteria,1NZF7@1224|Proteobacteria,2W3P5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8866775_25	269799.Gmet_0790	1.248e-103	343.0	COG0412@1|root,COG0412@2|Bacteria,1MW7S@1224|Proteobacteria,42Q9U@68525|delta/epsilon subdivisions,2X5CC@28221|Deltaproteobacteria,43UFH@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
REGS1_k127_8866775_31	497965.Cyan7822_0352	4.423e-81	288.0	COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria,3KJNP@43988|Cyanothece	1117|Cyanobacteria	T	histidine kinase A domain protein	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
REGS1_k127_8879316_7	243231.GSU1686	4.091e-84	282.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,43U1G@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM CMP dCMP deaminase zinc-binding	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
REGS1_k127_8879316_12	316067.Geob_2674	1.318e-65	228.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,43UTR@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
REGS1_k127_8879316_5	269799.Gmet_1624	1.491e-145	469.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,43T8J@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
REGS1_k127_8879316_9	243231.GSU1689	1.269e-76	261.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,42QT1@68525|delta/epsilon subdivisions,2WNK6@28221|Deltaproteobacteria,43UMU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
REGS1_k127_8879316_2	269799.Gmet_1441	4.204e-185	586.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,43T82@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
REGS1_k127_8879316_13	269799.Gmet_1440	1.206e-24	106.0	2EJQV@1|root,33DFP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8879316_11	338966.Ppro_1901	1.415e-72	250.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42URP@68525|delta/epsilon subdivisions,2WQFZ@28221|Deltaproteobacteria,43UTN@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
REGS1_k127_8879316_3	398767.Glov_0424	1.363e-184	586.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MSP@68525|delta/epsilon subdivisions,2WJM0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	nifV	-	2.3.3.14	ko:K02594	ko00620,map00620	-	R00271	RC00004,RC00067,RC02754	ko00000,ko00001,ko01000	-	-	-	HMGL-like
REGS1_k127_8879316_8	398767.Glov_1063	4.138e-80	273.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,42TJM@68525|delta/epsilon subdivisions,2WQGN@28221|Deltaproteobacteria,43SMB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
REGS1_k127_8879316_10	443144.GM21_2830	3.789e-75	261.0	COG0730@1|root,COG0730@2|Bacteria,1RD5A@1224|Proteobacteria	1224|Proteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
REGS1_k127_8879316_4	316067.Geob_2574	9.259e-172	546.0	COG1348@1|root,COG1348@2|Bacteria,1MVTE@1224|Proteobacteria,42NE5@68525|delta/epsilon subdivisions,2WJ14@28221|Deltaproteobacteria,43T0P@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein	nifH	-	1.18.6.1	ko:K02588	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_NifH
REGS1_k127_8879316_1	316067.Geob_2575	3.511e-294	904.0	COG2710@1|root,COG2710@2|Bacteria,1MVY2@1224|Proteobacteria,42MMI@68525|delta/epsilon subdivisions,2WJZI@28221|Deltaproteobacteria,43TBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifD	-	1.18.6.1	ko:K02586	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
REGS1_k127_8879316_0	316067.Geob_2577	1.297e-297	915.0	COG2710@1|root,COG2710@2|Bacteria,1MWQ4@1224|Proteobacteria,42MNG@68525|delta/epsilon subdivisions,2WIWX@28221|Deltaproteobacteria,43SY6@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation	nifK	-	1.18.6.1	ko:K02591	ko00625,ko00910,ko01100,ko01120,map00625,map00910,map01100,map01120	M00175	R05185,R05496	RC00002,RC01395,RC02891	ko00000,ko00001,ko00002,ko01000	-	-	-	Oxidored_nitro
REGS1_k127_8879316_6	398767.Glov_0466	8.318e-102	336.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,42MBY@68525|delta/epsilon subdivisions,2WIR5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
REGS1_k127_8899991_26	1297742.A176_05825	8.224e-07	61.0	COG4932@1|root,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,RCC1_2
REGS1_k127_8899991_0	269799.Gmet_1215	0.0	1740.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,43SUG@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
REGS1_k127_8899991_8	316067.Geob_3292	3.698e-165	523.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,43UDE@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
REGS1_k127_8899991_13	398767.Glov_2141	1.516e-94	312.0	COG4185@1|root,COG4185@2|Bacteria,1RFDC@1224|Proteobacteria,42TT0@68525|delta/epsilon subdivisions,2WQEY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
REGS1_k127_8899991_1	1123360.thalar_02127	0.0	1148.0	COG0846@1|root,COG0846@2|Bacteria,1Q89F@1224|Proteobacteria,2U2PP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
REGS1_k127_8899991_4	338966.Ppro_3199	3.603e-186	591.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,42P1M@68525|delta/epsilon subdivisions,2WKJ2@28221|Deltaproteobacteria,43S3B@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	-	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
REGS1_k127_8899991_17	316067.Geob_1548	1.703e-59	215.0	COG0226@1|root,COG0226@2|Bacteria	2|Bacteria	P	phosphate ion binding	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_8899991_10	269799.Gmet_0858	6.17e-139	447.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WPDW@28221|Deltaproteobacteria,43U17@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Dimerisation domain of Zinc Transporter	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
REGS1_k127_8899991_3	316067.Geob_3446	1.211e-188	606.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,43UIB@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	PFAM phosphoesterase, RecJ domain protein	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
REGS1_k127_8899991_16	316067.Geob_3447	1.122e-70	244.0	COG0457@1|root,COG0457@2|Bacteria,1N0Q1@1224|Proteobacteria,42TBT@68525|delta/epsilon subdivisions,2WPII@28221|Deltaproteobacteria,43V2H@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_2,TPR_8
REGS1_k127_8899991_11	269799.Gmet_0855	4.954e-135	436.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,43TNS@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
REGS1_k127_8899991_2	243231.GSU2617	6.684e-277	859.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,43SXP@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
REGS1_k127_8899991_20	316067.Geob_3450	4.565e-45	165.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	TIGRFAM preprotein translocase, YajC subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
REGS1_k127_8899991_6	316067.Geob_3451	6.268e-183	578.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,43TNC@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
REGS1_k127_8899991_27	1347086.CCBA010000012_gene2030	1.114e-05	53.0	2AWWM@1|root,31NU5@2|Bacteria,1TZQ8@1239|Firmicutes,4II4F@91061|Bacilli,1ZJ4J@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8899991_25	269799.Gmet_1309	1.108e-07	54.0	COG1014@1|root,COG1014@2|Bacteria,1R92Y@1224|Proteobacteria,42QJI@68525|delta/epsilon subdivisions,2WNVM@28221|Deltaproteobacteria,43SH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	vorC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
REGS1_k127_8899991_5	933262.AXAM01000060_gene2890	7.58e-185	585.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42NJU@68525|delta/epsilon subdivisions,2WKA6@28221|Deltaproteobacteria,2MJK5@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
REGS1_k127_8899991_14	398767.Glov_2307	8.82e-83	279.0	COG1014@1|root,COG1014@2|Bacteria,1R92Y@1224|Proteobacteria,42QJI@68525|delta/epsilon subdivisions,2WNVM@28221|Deltaproteobacteria,43SH8@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	vorC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
REGS1_k127_8899991_9	398767.Glov_2308	1.969e-144	461.0	COG1013@1|root,COG1013@2|Bacteria,1N0HY@1224|Proteobacteria,42MTM@68525|delta/epsilon subdivisions,2WJS6@28221|Deltaproteobacteria,43S67@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	vorB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
REGS1_k127_8899991_7	398767.Glov_2309	5.919e-179	568.0	COG0674@1|root,COG0674@2|Bacteria,1MWCI@1224|Proteobacteria,42NJY@68525|delta/epsilon subdivisions,2WIW3@28221|Deltaproteobacteria,43S09@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein	vorA	-	1.2.7.11,1.2.7.3,1.2.7.7	ko:K00174,ko:K00186	ko00010,ko00020,ko00280,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197,R07160,R08566,R08567	RC00004,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1307	PFOR_II,POR_N
REGS1_k127_8899991_22	398767.Glov_2310	7.058e-28	114.0	COG1146@1|root,COG1146@2|Bacteria,1N9Z7@1224|Proteobacteria,42WFZ@68525|delta/epsilon subdivisions,2WRW5@28221|Deltaproteobacteria,43VUR@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	vorD	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4
REGS1_k127_8899991_23	443143.GM18_2531	4.55e-26	116.0	2DDAV@1|root,2ZHC8@2|Bacteria,1P8PH@1224|Proteobacteria,433GC@68525|delta/epsilon subdivisions,2WXB5@28221|Deltaproteobacteria,43VWN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
REGS1_k127_8899991_18	243231.GSU1423	4.606e-53	188.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,42SEH@68525|delta/epsilon subdivisions,2WQWW@28221|Deltaproteobacteria,43SKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	FG	PFAM histidine triad (HIT) protein	hinT	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
REGS1_k127_8899991_12	269799.Gmet_1222	5.922e-105	346.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,43S7C@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	ribosomal RNA methyltransferase RrmJ FtsJ	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
REGS1_k127_8899991_15	443143.GM18_1916	4.951e-75	258.0	COG1285@1|root,COG1285@2|Bacteria,1MURJ@1224|Proteobacteria,42RSE@68525|delta/epsilon subdivisions,2WP0K@28221|Deltaproteobacteria,43SGX@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
REGS1_k127_8899991_21	443144.GM21_1908	5.192e-43	168.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
REGS1_k127_8899991_19	443143.GM18_1914	5.053e-50	179.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,43UTI@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8911445_1	1123393.KB891316_gene1982	2.126e-187	597.0	COG0651@1|root,COG0651@2|Bacteria,1MVBA@1224|Proteobacteria,2VKBR@28216|Betaproteobacteria,1KSWH@119069|Hydrogenophilales	119069|Hydrogenophilales	CP	Proton-conducting membrane transporter	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
REGS1_k127_8911445_3	765913.ThidrDRAFT_4200	6.235e-141	466.0	COG0852@1|root,COG3261@1|root,COG0852@2|Bacteria,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,1RSJ4@1236|Gammaproteobacteria,1WWJR@135613|Chromatiales	135613|Chromatiales	C	NADH dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
REGS1_k127_8911445_6	697282.Mettu_2847	3.055e-62	218.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,1RNUG@1236|Gammaproteobacteria,1XEI8@135618|Methylococcales	135618|Methylococcales	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_q6
REGS1_k127_8911445_2	1163617.SCD_n02028	1.662e-152	489.0	COG0288@1|root,COG0288@2|Bacteria,1MXW3@1224|Proteobacteria,2VP29@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Carboxysome Shell Carbonic Anhydrase	-	-	-	-	-	-	-	-	-	-	-	-	CsoSCA
REGS1_k127_8911445_0	243231.GSU0890	0.0	1011.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria,43TM8@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
REGS1_k127_8911445_7	1123371.ATXH01000003_gene1973	1.136e-27	114.0	COG1254@1|root,COG1254@2|Bacteria,2GHZK@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
REGS1_k127_8911445_4	316067.Geob_0389	1.555e-134	438.0	COG2974@1|root,COG2974@2|Bacteria,1N4GC@1224|Proteobacteria,42RPT@68525|delta/epsilon subdivisions,2WIWU@28221|Deltaproteobacteria,43S9R@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	Putative exonuclease, RdgC	-	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
REGS1_k127_8911445_5	1121918.ARWE01000001_gene456	4.311e-68	246.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BW2@68525|delta/epsilon subdivisions,2X8CJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PilZ
REGS1_k127_8911445_8	243231.GSU0767	9.281e-18	91.0	COG3637@1|root,COG3637@2|Bacteria,1NGKR@1224|Proteobacteria,42XMD@68525|delta/epsilon subdivisions,2WSIW@28221|Deltaproteobacteria,43UMH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
REGS1_k127_8911445_9	1120970.AUBZ01000018_gene3332	4.312e-10	69.0	COG5492@1|root,COG5492@2|Bacteria,1PZBJ@1224|Proteobacteria,1RZEW@1236|Gammaproteobacteria,46A4V@72275|Alteromonadaceae	1236|Gammaproteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF1566
REGS1_k127_8934390_61	686340.Metal_3240	6.827e-21	95.0	COG3668@1|root,COG3668@2|Bacteria,1N73M@1224|Proteobacteria,1T0H5@1236|Gammaproteobacteria,1XFY5@135618|Methylococcales	135618|Methylococcales	S	PFAM Plasmid stabilisation system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
REGS1_k127_8934390_65	686340.Metal_3239	1.716e-08	58.0	2DRB5@1|root,33B20@2|Bacteria	2|Bacteria	S	addiction module component	-	-	-	-	-	-	-	-	-	-	-	-	Unstab_antitox
REGS1_k127_8934390_50	1121422.AUMW01000013_gene1433	9.098e-79	263.0	COG0432@1|root,COG0432@2|Bacteria,1V201@1239|Firmicutes,24FTY@186801|Clostridia,261SP@186807|Peptococcaceae	186801|Clostridia	J	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
REGS1_k127_8934390_56	1232410.KI421426_gene1419	2.297e-51	188.0	COG2050@1|root,COG2050@2|Bacteria,1RH35@1224|Proteobacteria,42U19@68525|delta/epsilon subdivisions,2WR05@28221|Deltaproteobacteria,43V4G@69541|Desulfuromonadales	28221|Deltaproteobacteria	Q	Thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
REGS1_k127_8934390_47	269799.Gmet_0823	7.251e-95	319.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,42QMK@68525|delta/epsilon subdivisions,2X5B1@28221|Deltaproteobacteria,43S4F@69541|Desulfuromonadales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NmrA
REGS1_k127_8934390_48	443144.GM21_1336	1.715e-93	313.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2WNND@28221|Deltaproteobacteria,43T13@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
REGS1_k127_8934390_60	768710.DesyoDRAFT_0804	3.726e-30	127.0	COG2059@1|root,COG2059@2|Bacteria,1V43H@1239|Firmicutes,24JTX@186801|Clostridia,261U1@186807|Peptococcaceae	186801|Clostridia	P	chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
REGS1_k127_8934390_39	269799.Gmet_1355	1.607e-111	364.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,43UGT@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
REGS1_k127_8934390_0	316067.Geob_2401	2.414e-301	930.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
REGS1_k127_8934390_11	269799.Gmet_1353	1.219e-187	590.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,42M3V@68525|delta/epsilon subdivisions,2WJJ4@28221|Deltaproteobacteria,43T8H@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
REGS1_k127_8934390_43	443144.GM21_2383	3.679e-105	348.0	COG3409@1|root,COG3409@2|Bacteria,1NGBF@1224|Proteobacteria	1224|Proteobacteria	M	Domain of unknown function (DUF4384)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384
REGS1_k127_8934390_10	1123376.AUIU01000003_gene1634	8.898e-190	612.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
REGS1_k127_8934390_33	316067.Geob_3225	1.117e-123	407.0	COG3018@1|root,COG3018@2|Bacteria	2|Bacteria	-	-	-	-	3.2.1.23	ko:K01190,ko:K09860	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	FlgT_N
REGS1_k127_8934390_18	398767.Glov_1264	6.716e-165	527.0	COG0457@1|root,COG0457@2|Bacteria,1RKYJ@1224|Proteobacteria,42SSS@68525|delta/epsilon subdivisions,2WPW3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	SLH
REGS1_k127_8934390_34	316067.Geob_3221	3.28e-122	402.0	COG3018@1|root,COG3018@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09860	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_8934390_2	398767.Glov_1969	3.091e-286	894.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,42N5S@68525|delta/epsilon subdivisions,2WIUS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_8934390_32	398767.Glov_1970	4.576e-124	407.0	COG1729@1|root,COG4254@1|root,COG1729@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FecR,OmpA,TPR_16,TPR_6,cNMP_binding,fn3
REGS1_k127_8934390_3	316067.Geob_2399	4.84e-286	880.0	COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,42NM8@68525|delta/epsilon subdivisions,2WIWB@28221|Deltaproteobacteria,43T1E@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
REGS1_k127_8934390_16	243231.GSU1452	4.024e-166	534.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,43T7S@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
REGS1_k127_8934390_15	316067.Geob_2766	3.445e-166	527.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,42NRA@68525|delta/epsilon subdivisions,2WJ62@28221|Deltaproteobacteria,43TID@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1	fbp	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
REGS1_k127_8934390_41	243231.GSU1925	8.532e-108	355.0	COG1102@1|root,COG2823@1|root,COG1102@2|Bacteria,COG2823@2|Bacteria,1N42J@1224|Proteobacteria,42TW4@68525|delta/epsilon subdivisions,2WQ5J@28221|Deltaproteobacteria,43SXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	PFAM transport-associated	-	-	-	-	-	-	-	-	-	-	-	-	BON,Cytidylate_kin2
REGS1_k127_8934390_36	243231.GSU1514	8.584e-117	387.0	COG0859@1|root,COG0859@2|Bacteria,1N112@1224|Proteobacteria,42MUI@68525|delta/epsilon subdivisions,2WU9M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9
REGS1_k127_8934390_14	269799.Gmet_1397	9.277e-182	579.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,43UCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	response regulator	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_8934390_22	316067.Geob_3371	3.642e-150	492.0	COG5000@1|root,COG5000@2|Bacteria,1QVAT@1224|Proteobacteria,43BPZ@68525|delta/epsilon subdivisions,2X717@28221|Deltaproteobacteria,43TK3@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Sensor histidine kinase PilS, PAS domain-containing	pilS	-	2.7.13.3	ko:K02668,ko:K07709	ko02020,map02020	M00499,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_4
REGS1_k127_8934390_9	443143.GM18_2495	5.188e-202	634.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,43TBZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	PFAM type II secretion system	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
REGS1_k127_8934390_8	316067.Geob_3373	4.235e-207	647.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_8934390_4	1121918.ARWE01000001_gene1841	2.591e-282	876.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,43TCZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
REGS1_k127_8934390_6	316067.Geob_3376	4.505e-246	773.0	COG1807@1|root,COG1807@2|Bacteria,1N8ZV@1224|Proteobacteria,42WB6@68525|delta/epsilon subdivisions,2WRTT@28221|Deltaproteobacteria,43TNH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Protein of unknown function (DUF2723)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2723
REGS1_k127_8934390_31	316067.Geob_3377	8.533e-129	421.0	COG0392@1|root,COG0392@2|Bacteria,1R98C@1224|Proteobacteria,42U6V@68525|delta/epsilon subdivisions,2WKTZ@28221|Deltaproteobacteria,43W1F@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
REGS1_k127_8934390_35	316067.Geob_3378	2.739e-118	388.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,43S5P@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	TIGRFAM riboflavin biosynthesis protein RibF	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
REGS1_k127_8934390_29	316067.Geob_3379	1.311e-131	424.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42YHH@68525|delta/epsilon subdivisions,2WU2V@28221|Deltaproteobacteria,43S20@69541|Desulfuromonadales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
REGS1_k127_8934390_21	269799.Gmet_1582	4.779e-157	501.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42NGR@68525|delta/epsilon subdivisions,2WIMA@28221|Deltaproteobacteria,43TMT@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6,5.4.99.58	ko:K01012,ko:K16180	ko00300,ko00780,ko01100,ko01120,map00300,map00780,map01100,map01120	M00123,M00573,M00577	R01078,R10010	RC00441,RC02995	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1582	BATS,Radical_SAM
REGS1_k127_8934390_51	404380.Gbem_2052	2.198e-78	269.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WPQK@28221|Deltaproteobacteria,43U6M@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
REGS1_k127_8934390_7	269799.Gmet_1580	1.11e-221	695.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,43S0E@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
REGS1_k127_8934390_13	243231.GSU1216	7.112e-183	587.0	COG4987@1|root,COG4987@2|Bacteria,1QU1P@1224|Proteobacteria,42M79@68525|delta/epsilon subdivisions,2WMAG@28221|Deltaproteobacteria,43TX8@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC transporter	cydC	-	-	ko:K16012	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
REGS1_k127_8934390_12	269799.Gmet_2634	1.45e-187	602.0	COG4988@1|root,COG4988@2|Bacteria,1QU1N@1224|Proteobacteria,42MNK@68525|delta/epsilon subdivisions,2WM0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD	cydD	-	-	ko:K16013	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
REGS1_k127_8934390_37	338966.Ppro_3383	1.718e-113	373.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,42Q9R@68525|delta/epsilon subdivisions,2WKU4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
REGS1_k127_8934390_46	443144.GM21_3405	4.016e-95	314.0	COG0463@1|root,COG0463@2|Bacteria,1R3WX@1224|Proteobacteria,42RNM@68525|delta/epsilon subdivisions,2WNI7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Protein of unknown function (DUF4254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4254
REGS1_k127_8934390_19	443144.GM21_3406	4.766e-162	516.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	heptosyltransferase ii	rfaF	-	-	ko:K02841,ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
REGS1_k127_8934390_27	443144.GM21_3407	8.8e-141	456.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K20999	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	Glyco_trans_1_4
REGS1_k127_8934390_20	269799.Gmet_1325	1.44e-160	512.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42M4C@68525|delta/epsilon subdivisions,2WJ1Q@28221|Deltaproteobacteria,43UJU@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	DegT/DnrJ/EryC1/StrS aminotransferase family	fdtB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_8934390_54	880073.Calab_0581	8.32e-54	192.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
REGS1_k127_8934390_57	865937.Gilli_0708	2.204e-50	183.0	COG1898@1|root,COG1898@2|Bacteria,4PKN3@976|Bacteroidetes,1I2XR@117743|Flavobacteriia	976|Bacteroidetes	M	WxcM-like, C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	FdtA
REGS1_k127_8934390_45	565033.GACE_1134	1.573e-95	321.0	arCOG03320@1|root,arCOG03320@2157|Archaea,2Y31T@28890|Euryarchaeota	28890|Euryarchaeota	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
REGS1_k127_8934390_38	1205753.A989_04381	9.012e-112	368.0	COG1621@1|root,COG1621@2|Bacteria,1RGK9@1224|Proteobacteria,1S0H5@1236|Gammaproteobacteria,1X976@135614|Xanthomonadales	135614|Xanthomonadales	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8934390_49	484022.Fphi_1257	4.175e-88	296.0	COG0110@1|root,COG0110@2|Bacteria,1RAKB@1224|Proteobacteria	1224|Proteobacteria	S	COG0110 Acetyltransferase (isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
REGS1_k127_8934390_55	52598.EE36_00170	1.238e-52	199.0	COG1215@1|root,COG1215@2|Bacteria,1RBGS@1224|Proteobacteria,2U6IQ@28211|Alphaproteobacteria,3ZZ57@60136|Sulfitobacter	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_8934390_24	443144.GM21_3409	1.598e-147	474.0	COG0297@1|root,COG0297@2|Bacteria	2|Bacteria	G	glycogen (starch) synthase activity	-	-	-	ko:K12989	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT4	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_8934390_30	316067.Geob_2113	8.485e-130	424.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_8934390_17	316067.Geob_2111	1.517e-165	526.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,42NEW@68525|delta/epsilon subdivisions,2WJNJ@28221|Deltaproteobacteria,43S6D@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
REGS1_k127_8934390_23	443144.GM21_3404	1.701e-148	477.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,42NRP@68525|delta/epsilon subdivisions,2X5EK@28221|Deltaproteobacteria,43SA7@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	PFAM glycosyl transferase family 9	-	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
REGS1_k127_8934390_64	861299.J421_3206	5.213e-14	74.0	COG2835@1|root,COG2835@2|Bacteria,1ZU7Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Trm112p-like protein	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
REGS1_k127_8934390_40	404380.Gbem_0848	2.177e-111	370.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,42PA2@68525|delta/epsilon subdivisions,2WNJ4@28221|Deltaproteobacteria,43SX0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
REGS1_k127_8934390_25	269799.Gmet_2348	4.5e-147	477.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,42PCH@68525|delta/epsilon subdivisions,2WMQM@28221|Deltaproteobacteria,43TBC@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
REGS1_k127_8934390_58	1121918.ARWE01000001_gene1154	3.229e-50	186.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42UW6@68525|delta/epsilon subdivisions,2WQ4A@28221|Deltaproteobacteria,43T0K@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
REGS1_k127_8934390_5	316067.Geob_2103	2.805e-260	812.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2WJ7M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_8934390_26	316067.Geob_2102	8.316e-141	456.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,42P35@68525|delta/epsilon subdivisions,2WJFA@28221|Deltaproteobacteria,43SZS@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
REGS1_k127_8934390_44	269799.Gmet_2352	1.082e-104	349.0	COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,42NV0@68525|delta/epsilon subdivisions,2WK1Y@28221|Deltaproteobacteria,43T3I@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	gnnA	-	-	ko:K09949	-	-	-	-	ko00000	-	-	iAF987.Gmet_2352	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_8934390_42	316067.Geob_2101	8.19e-106	348.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,42NPG@68525|delta/epsilon subdivisions,2WJVP@28221|Deltaproteobacteria,43RXH@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
REGS1_k127_8934390_53	269799.Gmet_2354	4.003e-62	217.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,43UKW@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
REGS1_k127_8934390_28	316067.Geob_2099	1.116e-139	452.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,43TUE@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
REGS1_k127_8934390_52	404380.Gbem_0840	1.636e-63	222.0	COG2825@1|root,COG2825@2|Bacteria	2|Bacteria	M	unfolded protein binding	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
REGS1_k127_8934390_1	316067.Geob_2097	4.361e-300	939.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,43UEF@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
REGS1_k127_8934390_66	316067.Geob_2096	2.812e-05	46.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,43SYM@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
REGS1_k127_8979623_15	1163409.UUA_12860	1.57e-115	407.0	COG1361@1|root,COG1572@1|root,COG2234@1|root,COG4733@1|root,COG1361@2|Bacteria,COG1572@2|Bacteria,COG2234@2|Bacteria,COG4733@2|Bacteria,1N837@1224|Proteobacteria,1RZXI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_40	661478.OP10G_0926	2.549e-19	94.0	COG0745@1|root,COG0745@2|Bacteria	661478.OP10G_0926|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_13	243231.GSU0881	2.201e-124	416.0	COG4251@1|root,COG5000@1|root,COG4251@2|Bacteria,COG5000@2|Bacteria,1QXNE@1224|Proteobacteria	1224|Proteobacteria	T	Signal transduction Histidine	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_8979623_18	316067.Geob_1003	1.304e-103	343.0	COG0664@1|root,COG0664@2|Bacteria,1MZZD@1224|Proteobacteria,42QUX@68525|delta/epsilon subdivisions,2WMWV@28221|Deltaproteobacteria,43TZ5@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	fnr-1	-	-	ko:K01420,ko:K21563	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_8979623_23	316067.Geob_0969	4.734e-86	298.0	2DE9Y@1|root,2ZM4N@2|Bacteria,1Q17X@1224|Proteobacteria,43756@68525|delta/epsilon subdivisions,2X21C@28221|Deltaproteobacteria,43SFZ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_25	269799.Gmet_0175	6.349e-82	284.0	COG0791@1|root,COG0791@2|Bacteria,1NRCV@1224|Proteobacteria,42YTE@68525|delta/epsilon subdivisions,2WUEN@28221|Deltaproteobacteria,43U28@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_38	316067.Geob_0955	3.207e-35	136.0	2DQTP@1|root,338M6@2|Bacteria,1NA5P@1224|Proteobacteria,42WPZ@68525|delta/epsilon subdivisions,2WRZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_31	338966.Ppro_0930	3.04e-57	206.0	28QXJ@1|root,2ZDCN@2|Bacteria,1PA74@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_11	316067.Geob_1169	3.574e-137	444.0	COG0491@1|root,COG0491@2|Bacteria,1MXKX@1224|Proteobacteria,42R8E@68525|delta/epsilon subdivisions,2WN6V@28221|Deltaproteobacteria,43TY5@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_8979623_33	269799.Gmet_2290	1.461e-54	199.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,42USC@68525|delta/epsilon subdivisions,2WQMY@28221|Deltaproteobacteria,43UZV@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_8979623_9	243231.GSU2637	2.927e-180	567.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42PGW@68525|delta/epsilon subdivisions,2WMMZ@28221|Deltaproteobacteria,43TCD@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_8979623_35	269799.Gmet_0817	7.384e-49	177.0	2EJRN@1|root,33DGE@2|Bacteria,1NKN4@1224|Proteobacteria,42XH7@68525|delta/epsilon subdivisions,2WT06@28221|Deltaproteobacteria,43VBQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_34	443143.GM18_0305	1.55e-53	193.0	COG3437@1|root,COG3437@2|Bacteria	2|Bacteria	T	response regulator, receiver	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	EAL,GGDEF,PAS_4,PAS_8,Response_reg
REGS1_k127_8979623_22	443143.GM18_0303	6.3e-87	294.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,42R57@68525|delta/epsilon subdivisions,2WN5Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
REGS1_k127_8979623_16	443143.GM18_0302	6.534e-109	366.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42ZMH@68525|delta/epsilon subdivisions,2WV2I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
REGS1_k127_8979623_1	316067.Geob_3506	0.0	1108.0	COG2804@1|root,COG3437@1|root,COG2804@2|Bacteria,COG3437@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WKXB@28221|Deltaproteobacteria,43W1A@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	PFAM type II secretion system protein E	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE,T2SSE_N
REGS1_k127_8979623_20	404380.Gbem_0639	6.403e-97	327.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,43C4U@68525|delta/epsilon subdivisions,2WMNA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
REGS1_k127_8979623_28	316067.Geob_1321	3.051e-62	221.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,430ZC@68525|delta/epsilon subdivisions,2WW23@28221|Deltaproteobacteria,43V64@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_8979623_19	243231.GSU1376	1.174e-102	342.0	COG2043@1|root,COG2043@2|Bacteria,1R8EH@1224|Proteobacteria,42Q2F@68525|delta/epsilon subdivisions,2WJZN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
REGS1_k127_8979623_39	1232410.KI421424_gene1843	3.106e-24	103.0	2E98Y@1|root,333H8@2|Bacteria,1NCS3@1224|Proteobacteria,42W1Z@68525|delta/epsilon subdivisions,2WREJ@28221|Deltaproteobacteria,43SSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_42	225937.HP15_2728	3.57e-12	78.0	29JMV@1|root,306J6@2|Bacteria,1RDSQ@1224|Proteobacteria,1S492@1236|Gammaproteobacteria,469M6@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Protein of unknown function (DUF2860)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2860
REGS1_k127_8979623_29	1469607.KK073768_gene1319	2.163e-58	207.0	COG0242@1|root,COG0242@2|Bacteria,1G52N@1117|Cyanobacteria,1HKG9@1161|Nostocales	1117|Cyanobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
REGS1_k127_8979623_6	443143.GM18_0398	2.264e-190	599.0	COG1397@1|root,COG1397@2|Bacteria,1MXJP@1224|Proteobacteria,42Q0H@68525|delta/epsilon subdivisions,2WKF5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM ADP-ribosylation Crystallin J1	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
REGS1_k127_8979623_32	593750.Metfor_2797	5.604e-56	199.0	COG3832@1|root,arCOG09481@1|root,arCOG05261@2157|Archaea,arCOG09481@2157|Archaea,2XYEH@28890|Euryarchaeota,2NAYB@224756|Methanomicrobia	224756|Methanomicrobia	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
REGS1_k127_8979623_36	1121373.KB903640_gene3730	6.014e-44	187.0	COG2911@1|root,COG3291@1|root,COG4733@1|root,COG2911@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4NHHA@976|Bacteroidetes,47XBX@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CHU_C,Calx-beta,He_PIG,NHL,TIG,fn3
REGS1_k127_8979623_30	1459636.NTE_01486	4.827e-58	233.0	COG0726@1|root,COG4934@1|root,arCOG03561@1|root,arCOG09729@1|root,arCOG02876@2157|Archaea,arCOG03561@2157|Archaea,arCOG03665@2157|Archaea,arCOG09729@2157|Archaea,41T20@651137|Thaumarchaeota	2157|Archaea	G	xylanase chitin deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CHB_HEX_C_1,CarboxypepD_reg,Peptidase_S8,Polysacc_deac_1,Pro-kuma_activ
REGS1_k127_8979623_2	483219.LILAB_18585	0.0	1088.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	2|Bacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	AMPK1_CBM,Big_2,CHU_C,RCC1
REGS1_k127_8979623_3	398767.Glov_3594	1.246e-261	813.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,42N6C@68525|delta/epsilon subdivisions,2WJ66@28221|Deltaproteobacteria,43T5X@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
REGS1_k127_8979623_7	404380.Gbem_2765	4.628e-190	597.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,42MNJ@68525|delta/epsilon subdivisions,2WIZZ@28221|Deltaproteobacteria,43T1T@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
REGS1_k127_8979623_24	316067.Geob_1568	5.226e-86	289.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,42RGU@68525|delta/epsilon subdivisions,2WPHH@28221|Deltaproteobacteria,43UUF@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
REGS1_k127_8979623_27	316067.Geob_1567	1.088e-65	229.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,42RVM@68525|delta/epsilon subdivisions,2WQIY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
REGS1_k127_8979623_10	269799.Gmet_2848	6.984e-171	540.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,42MI2@68525|delta/epsilon subdivisions,2WJ5W@28221|Deltaproteobacteria,43UCQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2848	Pribosyl_synth,Pribosyltran_N
REGS1_k127_8979623_44	1387197.AWGA01000023_gene1079	3.079e-06	51.0	2EFWG@1|root,339NR@2|Bacteria,1NIWH@1224|Proteobacteria,1SHRN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8979623_17	443144.GM21_1446	4.022e-104	346.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,42RGS@68525|delta/epsilon subdivisions,2WNJR@28221|Deltaproteobacteria,43TCF@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
REGS1_k127_8979623_21	316067.Geob_0756	5.145e-88	297.0	COG3063@1|root,COG3063@2|Bacteria,1NSDK@1224|Proteobacteria,42YWV@68525|delta/epsilon subdivisions,2WUKY@28221|Deltaproteobacteria,43TMQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	NU	Type IV pilus biogenesis stability protein PilW	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
REGS1_k127_8979623_8	269799.Gmet_2556	6.663e-182	582.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,1MWKE@1224|Proteobacteria,42M5C@68525|delta/epsilon subdivisions,2WJ54@28221|Deltaproteobacteria,43U1B@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Lytic transglycosylase, SLT, LysM and LysM domain-containing	mltD2	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
REGS1_k127_8979623_14	1134474.O59_002436	2.891e-117	385.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,1RPRD@1236|Gammaproteobacteria,1FHT1@10|Cellvibrio	1236|Gammaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
REGS1_k127_8979623_12	1163408.UU9_09042	7.558e-125	405.0	COG5380@1|root,COG5380@2|Bacteria,1QG74@1224|Proteobacteria	1224|Proteobacteria	O	BRO family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bro-N
REGS1_k127_8979623_5	443143.GM18_0501	5.817e-216	678.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM RNA-directed DNA polymerase (Reverse transcriptase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
REGS1_k127_8979623_43	1255043.TVNIR_1131	2.931e-07	52.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,1RQP7@1236|Gammaproteobacteria,1X044@135613|Chromatiales	135613|Chromatiales	L	PFAM Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
REGS1_k127_8979623_26	452637.Oter_3829	6.002e-79	277.0	COG1524@1|root,COG1524@2|Bacteria,46VXF@74201|Verrucomicrobia,3K93S@414999|Opitutae	414999|Opitutae	S	Metalloenzyme superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
REGS1_k127_8979623_4	316067.Geob_1498	6.503e-227	716.0	COG0166@1|root,COG0166@2|Bacteria,1MUFP@1224|Proteobacteria,42MNB@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
REGS1_k127_8979623_37	338966.Ppro_1641	3.766e-36	142.0	2E3B5@1|root,32YAP@2|Bacteria,1N7KQ@1224|Proteobacteria,42W05@68525|delta/epsilon subdivisions,2WS7Z@28221|Deltaproteobacteria,43VK6@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2721
REGS1_k127_8979623_0	243231.GSU1564	0.0	1483.0	COG2902@1|root,COG2902@2|Bacteria,1MXNV@1224|Proteobacteria,42KZZ@68525|delta/epsilon subdivisions,2WJWV@28221|Deltaproteobacteria,43SQT@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM Glu Leu Phe Val dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH,ELFV_dehydrog
REGS1_k127_8999411_12	1341181.FLJC2902T_20800	2.083e-15	79.0	COG3271@1|root,COG3271@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C70
REGS1_k127_8999411_13	243365.CV_3391	1.456e-10	70.0	2EQF3@1|root,33I12@2|Bacteria,1NXWZ@1224|Proteobacteria,2W393@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8999411_14	443144.GM21_0368	1.36e-09	59.0	COG3636@1|root,COG3636@2|Bacteria,1N75D@1224|Proteobacteria,42V7U@68525|delta/epsilon subdivisions,2WS0W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	addiction module antidote protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8999411_9	338966.Ppro_3124	3.963e-30	123.0	COG1476@1|root,COG1476@2|Bacteria,1N8RN@1224|Proteobacteria,42VYR@68525|delta/epsilon subdivisions,2WRKD@28221|Deltaproteobacteria,43VHA@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_8999411_7	398767.Glov_1134	2.221e-45	165.0	2ECCJ@1|root,336AV@2|Bacteria,1N7MQ@1224|Proteobacteria,42VEF@68525|delta/epsilon subdivisions,2WRAA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8999411_1	316067.Geob_1001	4.43e-189	601.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42YF8@68525|delta/epsilon subdivisions,2WU6H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA-3	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
REGS1_k127_8999411_5	443144.GM21_1942	4.606e-82	281.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,T2SSE_N
REGS1_k127_8999411_4	316067.Geob_2255	6.488e-99	326.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1N3ZM@1224|Proteobacteria,42TUU@68525|delta/epsilon subdivisions,2WQ8Z@28221|Deltaproteobacteria,43TAJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	KP	PFAM iron dependent repressor	ideR	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,FeoA
REGS1_k127_8999411_10	316067.Geob_2254	2.319e-20	93.0	2DST5@1|root,33HC3@2|Bacteria,1NMTA@1224|Proteobacteria,42XYN@68525|delta/epsilon subdivisions,2WT9U@28221|Deltaproteobacteria,43VXG@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8999411_0	243231.GSU1380	2.076e-312	968.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria,43SY5@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB-1	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
REGS1_k127_8999411_6	316067.Geob_2252	6.666e-64	225.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,43UY7@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
REGS1_k127_8999411_3	338966.Ppro_2982	2.841e-104	348.0	COG4313@1|root,COG4313@2|Bacteria,1PC95@1224|Proteobacteria,42RHY@68525|delta/epsilon subdivisions,2WNBQ@28221|Deltaproteobacteria,43UWW@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Putative MetA-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
REGS1_k127_8999411_2	404380.Gbem_2669	2.365e-125	436.0	COG0834@1|root,COG4191@1|root,COG4936@1|root,COG0834@2|Bacteria,COG4191@2|Bacteria,COG4936@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	HATPase_c,HisKA,PAS_4,PocR,Response_reg,SBP_bac_3
REGS1_k127_8999411_11	269799.Gmet_0139	1.259e-18	95.0	COG5295@1|root,COG5295@2|Bacteria	2|Bacteria	UW	Hep Hag repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase,YadA_stalk
REGS1_k127_8999411_15	1244869.H261_13194	1.686e-07	54.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2UMW2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4
REGS1_k127_9035877_4	269799.Gmet_0212	3.26e-162	513.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,43SW3@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
REGS1_k127_9035877_3	269799.Gmet_0211	1.033e-171	541.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,43SVU@69541|Desulfuromonadales	28221|Deltaproteobacteria	EM	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
REGS1_k127_9035877_8	443143.GM18_4100	1.709e-48	184.0	COG4733@1|root,COG4733@2|Bacteria,1N6GF@1224|Proteobacteria,42TSM@68525|delta/epsilon subdivisions,2WQ4Y@28221|Deltaproteobacteria,43SNQ@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9035877_0	316067.Geob_1127	9.78e-262	810.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,42M7Y@68525|delta/epsilon subdivisions,2WIRN@28221|Deltaproteobacteria,43TB5@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM fumarate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1,NUDIX
REGS1_k127_9035877_7	240016.ABIZ01000001_gene2870	3.639e-71	248.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	crtF	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_2,Methyltransf_23
REGS1_k127_9035877_1	398767.Glov_3148	2.851e-243	754.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
REGS1_k127_9035877_5	269799.Gmet_0205	6.036e-158	503.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,42M0Q@68525|delta/epsilon subdivisions,2WJ3G@28221|Deltaproteobacteria,43TZK@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.9	ko:K00611,ko:K09065	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01398,R07245	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_9035877_2	398767.Glov_3150	1.109e-220	691.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,43RZ9@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
REGS1_k127_907022_2	443144.GM21_0774	2.993e-62	216.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,42NZH@68525|delta/epsilon subdivisions,2WKHB@28221|Deltaproteobacteria,43T4R@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
REGS1_k127_907022_4	338966.Ppro_0863	1.57e-34	136.0	COG0640@1|root,COG0640@2|Bacteria,1MZT1@1224|Proteobacteria,42VSP@68525|delta/epsilon subdivisions,2WRGT@28221|Deltaproteobacteria,43VD5@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	PFAM regulatory protein, ArsR	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
REGS1_k127_907022_3	338966.Ppro_0842	3.955e-61	213.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,42RQI@68525|delta/epsilon subdivisions,2WPJD@28221|Deltaproteobacteria,43V2U@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Low molecular weight phosphatase family	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
REGS1_k127_907022_1	1267535.KB906767_gene1983	2.115e-159	510.0	COG0798@1|root,COG0798@2|Bacteria,3Y69M@57723|Acidobacteria,2JP2H@204432|Acidobacteriia	57723|Acidobacteria	P	Sodium Bile acid symporter family	-	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
REGS1_k127_907022_0	1254432.SCE1572_04645	2.273e-186	594.0	COG0003@1|root,COG0003@2|Bacteria,1MUTX@1224|Proteobacteria,42MT4@68525|delta/epsilon subdivisions,2WKZD@28221|Deltaproteobacteria,2Z34N@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
REGS1_k127_9081740_12	316067.Geob_2609	4.928e-46	169.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,43V81@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
REGS1_k127_9081740_14	269799.Gmet_1597	1.327e-28	115.0	COG0333@1|root,COG0333@2|Bacteria,1NGM1@1224|Proteobacteria,42XHF@68525|delta/epsilon subdivisions,2WSX6@28221|Deltaproteobacteria,43SSW@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	structural constituent of ribosome	rpmF	GO:0003674,GO:0003735,GO:0005198	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
REGS1_k127_9081740_4	269799.Gmet_1598	1.068e-171	544.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,42NRV@68525|delta/epsilon subdivisions,2WIXX@28221|Deltaproteobacteria,43T0B@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
REGS1_k127_9081740_6	316067.Geob_2612	3.792e-151	483.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,43S1E@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH-2	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_9081740_8	243231.GSU1602	3.022e-140	451.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,43UBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
REGS1_k127_9081740_10	398767.Glov_1937	1.039e-68	235.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,43UKW@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
REGS1_k127_9081740_9	398767.Glov_1936	1.047e-127	411.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,43T1X@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	KR domain	fabG-2	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_9081740_13	316067.Geob_2615	8.779e-34	131.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,43SPX@69541|Desulfuromonadales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_9081740_2	338966.Ppro_1746	8.87e-231	719.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,43TSR@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_9081740_11	269799.Gmet_1604	1.075e-60	213.0	COG0698@1|root,COG0698@2|Bacteria,1RHBF@1224|Proteobacteria,42SAN@68525|delta/epsilon subdivisions,2WP1V@28221|Deltaproteobacteria,43UNK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1604	LacAB_rpiB
REGS1_k127_9081740_1	398767.Glov_1932	1.492e-240	746.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,43U6J@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
REGS1_k127_9081740_16	1211814.CAPG01000092_gene4229	1.578e-09	58.0	29S0J@1|root,30D4W@2|Bacteria,1UAUR@1239|Firmicutes,4IM7J@91061|Bacilli,1ZJEQ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9081740_5	269799.Gmet_1312	6.158e-155	494.0	COG0451@1|root,COG0451@2|Bacteria,1MUGT@1224|Proteobacteria,42M12@68525|delta/epsilon subdivisions,2WIJX@28221|Deltaproteobacteria,43T70@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1312	Epimerase
REGS1_k127_9081740_3	338966.Ppro_3405	3.632e-201	629.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,43T4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_9081740_0	269799.Gmet_2184	4.126e-292	921.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42M62@68525|delta/epsilon subdivisions,2WJ83@28221|Deltaproteobacteria,43U6W@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Capsule biosynthesis GfcC	-	-	-	-	-	-	-	-	-	-	-	-	Caps_synth_GfcC,Poly_export,SLBB
REGS1_k127_9081740_7	398767.Glov_1510	9.083e-143	456.0	COG0673@1|root,COG0673@2|Bacteria,1PXE1@1224|Proteobacteria,42MSE@68525|delta/epsilon subdivisions,2WKIS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13016	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
REGS1_k127_911608_25	316067.Geob_2328	6.027e-13	71.0	COG1414@1|root,COG1414@2|Bacteria,1R66I@1224|Proteobacteria	1224|Proteobacteria	K	IclR helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
REGS1_k127_911608_15	338966.Ppro_1076	1.266e-56	203.0	COG1846@1|root,COG1846@2|Bacteria,1RF8X@1224|Proteobacteria,43AC3@68525|delta/epsilon subdivisions,2X5RZ@28221|Deltaproteobacteria,43UX1@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
REGS1_k127_911608_5	316067.Geob_1802	2.589e-162	513.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,42MJU@68525|delta/epsilon subdivisions,2WJS4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	UTP-glucose-1-phosphate uridylyltransferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
REGS1_k127_911608_8	316067.Geob_1801	2.256e-121	395.0	COG0685@1|root,COG0685@2|Bacteria,1MXTZ@1224|Proteobacteria,42NTS@68525|delta/epsilon subdivisions,2WK04@28221|Deltaproteobacteria,43V05@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF-1	-	1.5.1.20,2.1.1.10	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	M00377	R00650,R01224,R07168	RC00003,RC00035,RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
REGS1_k127_911608_12	316067.Geob_1800	4.08e-96	318.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WKM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
REGS1_k127_911608_6	443143.GM18_1332	1.25e-149	476.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1162	THF_DHG_CYH,THF_DHG_CYH_C
REGS1_k127_911608_22	316067.Geob_1798	5.867e-31	123.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,43VFN@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
REGS1_k127_911608_23	269799.Gmet_1164	2.169e-26	111.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,42VE5@68525|delta/epsilon subdivisions,2WR8T@28221|Deltaproteobacteria,43VHW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
REGS1_k127_911608_14	269799.Gmet_1165	4.899e-58	204.0	COG3599@1|root,COG3599@2|Bacteria,1NCAV@1224|Proteobacteria,42VH6@68525|delta/epsilon subdivisions,2WS27@28221|Deltaproteobacteria	28221|Deltaproteobacteria	D	PFAM DivIVA family protein	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
REGS1_k127_911608_21	269799.Gmet_1166	6.88e-37	141.0	COG0762@1|root,COG0762@2|Bacteria,1QDB9@1224|Proteobacteria,42VCU@68525|delta/epsilon subdivisions,2WRHX@28221|Deltaproteobacteria,43VQH@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
REGS1_k127_911608_13	243231.GSU0672	3.408e-77	265.0	COG1102@1|root,COG1102@2|Bacteria,1R9XZ@1224|Proteobacteria,43766@68525|delta/epsilon subdivisions,2X252@28221|Deltaproteobacteria,43SV0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
REGS1_k127_911608_18	443144.GM21_3023	3.296e-47	172.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,43VJF@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
REGS1_k127_911608_4	269799.Gmet_1883	2.045e-172	555.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,43T92@69541|Desulfuromonadales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
REGS1_k127_911608_16	443143.GM18_1120	1.517e-56	201.0	COG3448@1|root,COG3448@2|Bacteria,1QXNX@1224|Proteobacteria,43C4S@68525|delta/epsilon subdivisions,2X7F6@28221|Deltaproteobacteria,43UX4@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
REGS1_k127_911608_20	1121428.DESHY_160205___1	4.78e-44	166.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,2621R@186807|Peptococcaceae	186801|Clostridia	S	PFAM Uncharacterised P-loop hydrolase UPF0079	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
REGS1_k127_911608_2	269799.Gmet_1880	2.472e-220	687.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,42NDT@68525|delta/epsilon subdivisions,2WIWZ@28221|Deltaproteobacteria,43U9Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	PFAM aspartate glutamate uridylate kinase	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
REGS1_k127_911608_0	269799.Gmet_1879	9.937e-308	949.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,43TBU@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
REGS1_k127_911608_24	316067.Geob_2936	2.74e-22	96.0	2EI4B@1|root,33BVP@2|Bacteria,1P7YE@1224|Proteobacteria,432QQ@68525|delta/epsilon subdivisions,2WY5G@28221|Deltaproteobacteria,43VR5@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_911608_11	316067.Geob_0427	4.609e-102	340.0	COG0463@1|root,COG0463@2|Bacteria,1RCVF@1224|Proteobacteria,43CNQ@68525|delta/epsilon subdivisions,2WUDG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
REGS1_k127_911608_1	398767.Glov_1822	2.353e-269	832.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,42MK4@68525|delta/epsilon subdivisions,2WJJ8@28221|Deltaproteobacteria,43S8N@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PFAM TRAP C4-dicarboxylate transport system permease DctM subunit	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
REGS1_k127_911608_7	398767.Glov_1823	6.234e-125	403.0	COG3090@1|root,COG3090@2|Bacteria,1R3YK@1224|Proteobacteria,43B1I@68525|delta/epsilon subdivisions	1224|Proteobacteria	G	PFAM Tripartite ATP-independent periplasmic transporter DctQ component	dctQ	GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0022857,GO:0034220,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1903825,GO:1905039	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
REGS1_k127_911608_3	398767.Glov_1824	4.683e-182	573.0	COG1638@1|root,COG1638@2|Bacteria,1MVHC@1224|Proteobacteria,42M9R@68525|delta/epsilon subdivisions,2WKQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	TRAP dicarboxylate transporter, DctP subunit	-	-	-	ko:K11688	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctP
REGS1_k127_911608_17	243231.GSU2010	3.037e-49	179.0	COG0517@1|root,COG0517@2|Bacteria,1RA25@1224|Proteobacteria,42R80@68525|delta/epsilon subdivisions,2WMW6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K04767	-	-	-	-	ko00000	-	-	-	CBS
REGS1_k127_911608_9	1121440.AUMA01000009_gene681	4.213e-107	351.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42MSC@68525|delta/epsilon subdivisions,2WJAH@28221|Deltaproteobacteria,2MGE1@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
REGS1_k127_911608_10	1121440.AUMA01000009_gene682	2.109e-105	350.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria,2M9HK@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	pfam abc	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_911608_19	1125863.JAFN01000001_gene1063	6.349e-45	165.0	COG4177@1|root,COG4177@2|Bacteria,1MU52@1224|Proteobacteria,42RI3@68525|delta/epsilon subdivisions,2WNVC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_9220144_1	1168289.AJKI01000004_gene2945	4.616e-40	155.0	COG2885@1|root,COG2885@2|Bacteria,4NI3U@976|Bacteroidetes,2FQF1@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl_2,OmpA
REGS1_k127_9220144_2	338969.Rfer_1442	1.129e-20	93.0	2CHW3@1|root,32S6N@2|Bacteria,1N0I3@1224|Proteobacteria,2VW65@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mitomycin resistance protein	mcrB	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	Cdd1
REGS1_k127_9220144_0	316067.Geob_0607	6.673e-152	488.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
REGS1_k127_93549_5	709986.Deima_3071	1.692e-24	116.0	COG0628@1|root,COG0628@2|Bacteria,1WIXU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	COGs COG0628 permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_93549_2	357804.Ping_2504	2.054e-97	321.0	COG2201@1|root,COG2201@2|Bacteria,1QJYZ@1224|Proteobacteria,1S01C@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	PFAM CheB methylesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest
REGS1_k127_93549_6	443143.GM18_1226	3.942e-23	101.0	COG1141@1|root,COG1141@2|Bacteria	2|Bacteria	C	electron transfer activity	frx-5	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13
REGS1_k127_93549_4	330214.NIDE0044	9.558e-55	195.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	osmC	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
REGS1_k127_93549_1	316067.Geob_2905	4.379e-154	494.0	COG1607@1|root,COG1607@2|Bacteria,1Q9RF@1224|Proteobacteria,42Q5P@68525|delta/epsilon subdivisions,2WJY5@28221|Deltaproteobacteria,43UIK@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
REGS1_k127_93549_0	316067.Geob_3788	7.341e-182	578.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MP5@68525|delta/epsilon subdivisions,2WPWF@28221|Deltaproteobacteria,43UPY@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118,HATPase_c,PAS_4,Response_reg
REGS1_k127_93549_3	1149133.ppKF707_0937	1.203e-89	300.0	COG0693@1|root,COG0693@2|Bacteria,1MVTT@1224|Proteobacteria,1RPVK@1236|Gammaproteobacteria,1YEWI@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
REGS1_k127_93549_7	443143.GM18_2737	1.915e-13	70.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_944623_8	316067.Geob_3274	6.004e-34	132.0	COG2220@1|root,COG2220@2|Bacteria,1MUY6@1224|Proteobacteria,42Q5T@68525|delta/epsilon subdivisions,2WUTJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_3
REGS1_k127_944623_2	443143.GM18_0295	4.181e-124	409.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,42NS9@68525|delta/epsilon subdivisions,2WJMJ@28221|Deltaproteobacteria,43SCR@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
REGS1_k127_944623_0	269799.Gmet_2983	0.0	1332.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,42NAV@68525|delta/epsilon subdivisions,2WJ3W@28221|Deltaproteobacteria,43TIJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
REGS1_k127_944623_3	331678.Cphamn1_0131	1.126e-85	291.0	COG0551@1|root,COG0551@2|Bacteria,1FF2M@1090|Chlorobi	1090|Chlorobi	L	PFAM DNA topoisomerase type IA zn finger domain protein	-	-	-	-	-	-	-	-	-	-	-	-	23S_rRNA_IVP,zf-C4_Topoisom
REGS1_k127_944623_6	398767.Glov_2730	9.455e-41	151.0	COG1550@1|root,COG1550@2|Bacteria,1NGDU@1224|Proteobacteria,42XQ5@68525|delta/epsilon subdivisions,2WTAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF503)	-	-	-	ko:K09764	-	-	-	-	ko00000	-	-	-	DUF503
REGS1_k127_944623_9	243231.GSU0540	4.457e-21	93.0	2EE6A@1|root,3380W@2|Bacteria,1NCBW@1224|Proteobacteria,42V9R@68525|delta/epsilon subdivisions,2WSI3@28221|Deltaproteobacteria,43VQV@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_944623_4	269799.Gmet_2986	1.195e-66	229.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ7I@28221|Deltaproteobacteria,43UXA@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Hsp20/alpha crystallin family	hspA-1	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
REGS1_k127_944623_11	1459636.NTE_00310	1.089e-05	53.0	COG0726@1|root,COG3291@1|root,arCOG02508@2157|Archaea,arCOG02876@2157|Archaea,41T20@651137|Thaumarchaeota	2157|Archaea	G	xylanase chitin deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CHB_HEX_C_1,HYR,Polysacc_deac_1
REGS1_k127_944623_1	269799.Gmet_1613	2.5e-322	1005.0	COG0204@1|root,COG1022@1|root,COG0204@2|Bacteria,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,43TKN@69541|Desulfuromonadales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C,Acyltransferase,PP-binding
REGS1_k127_944623_5	316067.Geob_3655	6.779e-66	240.0	COG1413@1|root,COG1413@2|Bacteria,1QX4H@1224|Proteobacteria,42Z02@68525|delta/epsilon subdivisions,2WUJ9@28221|Deltaproteobacteria,43VYE@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,T2SSE_N
REGS1_k127_944623_10	443143.GM18_1184	4.451e-11	64.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria	1224|Proteobacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
REGS1_k127_984768_4	1528098.NOVO_03935	4.939e-28	131.0	COG2199@1|root,COG3437@1|root,COG3437@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2TQQM@28211|Alphaproteobacteria,47F0K@766|Rickettsiales	766|Rickettsiales	T	response regulator containing a CheY-like receiver domain and a GGDEF domain	pleD	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	GGDEF,Response_reg
REGS1_k127_984768_3	1333507.AUTQ01000242_gene1792	5.28e-82	297.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,1T1JE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K20974	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg,dCache_1
REGS1_k127_984768_5	1032480.MLP_28130	2.516e-20	94.0	COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4DNTM@85009|Propionibacteriales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K02483,ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_984768_0	338966.Ppro_0396	1.582e-227	730.0	COG2304@1|root,COG2885@1|root,COG2304@2|Bacteria,COG2885@2|Bacteria,1N20X@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
REGS1_k127_984768_2	1121918.ARWE01000001_gene1624	5.403e-185	587.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,42PV9@68525|delta/epsilon subdivisions,2WKF2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
REGS1_k127_984768_1	443144.GM21_2012	5.29e-209	655.0	COG0477@1|root,COG2814@2|Bacteria,1NU31@1224|Proteobacteria,43CB2@68525|delta/epsilon subdivisions,2X7MH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EGP	Major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
## 2996 queries scanned
## Total time (seconds): 179.18754816055298
## Rate: 16.72 q/s