## Thu Oct 17 15:36:47 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/Potential_rubisco_autotrophic/REGS1_bin.47.fa -m mmseqs --itype genome -o REGS1_bin.47 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/all_bins_1385/REGS1_bin.47 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
REGS1_k127_1083974_0	580332.Slit_0879	2.409e-276	876.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W76@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS_3,PAS_9
REGS1_k127_1083974_4	580332.Slit_1184	1.759e-75	262.0	COG2200@1|root,COG3829@1|root,COG2200@2|Bacteria,COG3829@2|Bacteria,1NTHT@1224|Proteobacteria,2W1FA@28216|Betaproteobacteria,44WAB@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	TIGRFAM PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PAS_4
REGS1_k127_1083974_3	395494.Galf_1181	3.73e-104	347.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria,44WDG@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	PFAM Serine threonine-protein kinase-like domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
REGS1_k127_1083974_5	395494.Galf_1648	1.192e-55	199.0	2D2K4@1|root,32TD0@2|Bacteria,1MZKF@1224|Proteobacteria,2VUUX@28216|Betaproteobacteria,44WIR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3124
REGS1_k127_1083974_1	580332.Slit_2158	2.442e-163	520.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,44V8T@713636|Nitrosomonadales	1224|Proteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
REGS1_k127_1083974_6	580332.Slit_1563	8.162e-18	90.0	2DSWJ@1|root,33HQ5@2|Bacteria,1NICM@1224|Proteobacteria,2VYFK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
REGS1_k127_1083974_2	580332.Slit_1332	9.993e-139	447.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,2VMHH@28216|Betaproteobacteria,44WAD@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM cation diffusion facilitator family transporter	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux,ZT_dimer
REGS1_k127_1147143_4	580332.Slit_1758	5.752e-97	319.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,44V30@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
REGS1_k127_1147143_2	580332.Slit_1757	2.368e-159	507.0	COG0564@1|root,COG0564@2|Bacteria,1MVDX@1224|Proteobacteria,2VI51@28216|Betaproteobacteria,44VCM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_1147143_5	153721.MYP_3290	4.917e-12	72.0	2DZX8@1|root,32VMB@2|Bacteria,4P0QT@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1147143_3	580332.Slit_0497	3.756e-134	438.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,44VBF@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Type II secretion system F domain	-	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
REGS1_k127_1147143_1	580332.Slit_0498	1.436e-226	713.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	type II secretion system protein E	gspE	-	-	ko:K02454,ko:K02652,ko:K12276	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSE,T2SSE_N
REGS1_k127_1147143_0	580332.Slit_0499	2.802e-237	752.0	COG1450@1|root,COG1450@2|Bacteria,1MUUA@1224|Proteobacteria,2VI7X@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	general secretion pathway protein D	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
REGS1_k127_1150316_0	1485544.JQKP01000001_gene1327	9.115e-191	597.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,44V4M@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd,dTDP_sugar_isom
REGS1_k127_1150316_1	580332.Slit_2909	1.09e-161	511.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,2VHA6@28216|Betaproteobacteria,44VIN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
REGS1_k127_1150316_3	580332.Slit_2910	6.645e-85	287.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,2VQ02@28216|Betaproteobacteria,44VRT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
REGS1_k127_1150316_2	1163617.SCD_n02910	7.468e-108	357.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
REGS1_k127_1171125_0	582744.Msip34_1075	0.0	2029.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria,2KNBM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
REGS1_k127_1171125_1	582744.Msip34_1076	7.362e-266	838.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2VMGW@28216|Betaproteobacteria,2KMZG@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Penicillin-Binding Protein C-terminus Family	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
REGS1_k127_1171125_2	580332.Slit_1987	1.624e-141	457.0	COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,2VK2D@28216|Betaproteobacteria,44V6Z@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM glycine cleavage T protein (aminomethyl transferase)	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
REGS1_k127_1171125_3	1485544.JQKP01000003_gene152	1.648e-65	228.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,44W8T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
REGS1_k127_1184195_27	1121930.AQXG01000001_gene1220	4.899e-52	192.0	COG2173@1|root,COG2173@2|Bacteria,4NE2K@976|Bacteroidetes	976|Bacteroidetes	M	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide	ddpX	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
REGS1_k127_1184195_29	1120985.AUMI01000003_gene665	2.075e-39	155.0	COG3786@1|root,COG3786@2|Bacteria,1VA6V@1239|Firmicutes,4H8ZQ@909932|Negativicutes	909932|Negativicutes	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_1184195_32	395494.Galf_0300	2.251e-16	84.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_1184195_3	580332.Slit_1056	5.494e-218	682.0	COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2VH9Q@28216|Betaproteobacteria,44V9F@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
REGS1_k127_1184195_0	580332.Slit_1057	0.0	1926.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,2VI4A@28216|Betaproteobacteria,44V81@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
REGS1_k127_1184195_21	1485544.JQKP01000008_gene1770	3.834e-83	278.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,2VQ16@28216|Betaproteobacteria,44VQE@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_1184195_30	395494.Galf_2255	5.32e-33	130.0	COG1534@1|root,COG1534@2|Bacteria,1N8K5@1224|Proteobacteria,2VVP0@28216|Betaproteobacteria,44VYX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	CRS1_YhbY	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
REGS1_k127_1184195_20	395494.Galf_2254	5.473e-86	288.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,2VIU9@28216|Betaproteobacteria,44UZM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
REGS1_k127_1184195_1	1123393.KB891327_gene367	1.026e-307	953.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,2VHEV@28216|Betaproteobacteria,1KRD9@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
REGS1_k127_1184195_13	580332.Slit_1062	7.404e-118	385.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,2VH2Q@28216|Betaproteobacteria,44V46@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
REGS1_k127_1184195_2	1485544.JQKP01000008_gene1765	5.204e-222	695.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,2VI3U@28216|Betaproteobacteria,44VBG@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_1184195_26	580332.Slit_2800	6.853e-69	243.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_1184195_11	580332.Slit_0818	5.098e-132	426.0	COG5660@1|root,2Z7TM@2|Bacteria,1PMCV@1224|Proteobacteria,2VWPY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TRAP transporter T-component	-	-	-	-	-	-	-	-	-	-	-	-	TAtT
REGS1_k127_1184195_9	580332.Slit_0817	3.242e-154	493.0	COG1638@1|root,COG1638@2|Bacteria,1PN6J@1224|Proteobacteria,2VSNQ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
REGS1_k127_1184195_24	580332.Slit_0816	4.976e-70	240.0	COG3090@1|root,COG3090@2|Bacteria,1PJMD@1224|Proteobacteria,2VYB1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
REGS1_k127_1184195_4	580332.Slit_0815	6.101e-215	674.0	COG1593@1|root,COG1593@2|Bacteria,1MU0F@1224|Proteobacteria,2VMTA@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
REGS1_k127_1184195_28	314345.SPV1_05158	6.812e-44	165.0	COG2703@1|root,COG2703@2|Bacteria,1NHAX@1224|Proteobacteria	1224|Proteobacteria	P	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
REGS1_k127_1184195_7	580332.Slit_1330	1.385e-172	562.0	COG0745@1|root,COG2206@1|root,COG3829@1|root,COG0745@2|Bacteria,COG2206@2|Bacteria,COG3829@2|Bacteria,1RAQS@1224|Proteobacteria,2VQE0@28216|Betaproteobacteria,44WFJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5,PAS_4
REGS1_k127_1184195_22	580332.Slit_1329	1.335e-78	265.0	COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,2WGQ0@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
REGS1_k127_1184195_19	386456.JQKN01000002_gene2414	2.539e-89	313.0	arCOG07605@1|root,arCOG07605@2157|Archaea,2XX6C@28890|Euryarchaeota	28890|Euryarchaeota	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_1184195_10	580332.Slit_1327	1.045e-151	526.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,1RGKE@1224|Proteobacteria,2WHFM@28216|Betaproteobacteria,44WPK@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
REGS1_k127_1184195_14	1485544.JQKP01000010_gene791	1.343e-115	382.0	COG3221@1|root,COG3221@2|Bacteria,1MX7I@1224|Proteobacteria,2VP4Q@28216|Betaproteobacteria,44VB1@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
REGS1_k127_1184195_12	580332.Slit_2570	3.009e-118	386.0	COG0300@1|root,COG0300@2|Bacteria,1PGBU@1224|Proteobacteria,2W9AF@28216|Betaproteobacteria,44WP6@713636|Nitrosomonadales	28216|Betaproteobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
REGS1_k127_1184195_18	580332.Slit_2306	4.83e-92	314.0	2DRTJ@1|root,33CZM@2|Bacteria,1QF7V@1224|Proteobacteria,2VXR2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3617)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3617
REGS1_k127_1184195_25	443144.GM21_3283	5.182e-69	243.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,42NZ8@68525|delta/epsilon subdivisions,2WK0Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258,ko:K07262	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
REGS1_k127_1184195_6	580332.Slit_2308	2.302e-179	572.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,2VX93@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
REGS1_k127_1184195_8	580332.Slit_2290	1.462e-163	517.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,2VIQ4@28216|Betaproteobacteria,44VGM@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
REGS1_k127_1184195_31	580332.Slit_2289	6.774e-25	112.0	COG3317@1|root,COG3317@2|Bacteria,1N670@1224|Proteobacteria,2VHS5@28216|Betaproteobacteria,44W4F@713636|Nitrosomonadales	28216|Betaproteobacteria	M	NlpB/DapX lipoprotein	nlpB	-	-	ko:K07287	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	Lipoprotein_18
REGS1_k127_1184195_15	580332.Slit_2288	3.731e-110	362.0	COG1235@1|root,COG1235@2|Bacteria,1R5N4@1224|Proteobacteria,2VKSE@28216|Betaproteobacteria,44V64@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
REGS1_k127_1184195_34	631362.Thi970DRAFT_03430	4.969e-16	84.0	COG4461@1|root,COG4461@2|Bacteria,1R6Q3@1224|Proteobacteria,1S2QD@1236|Gammaproteobacteria,1WZNG@135613|Chromatiales	135613|Chromatiales	G	Lysozyme inhibitor LprI	-	-	-	-	-	-	-	-	-	-	-	-	LprI
REGS1_k127_1184195_16	765913.ThidrDRAFT_4290	1.602e-108	371.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1T2K5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	metal-dependent phosphohydrolase, HD	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5
REGS1_k127_1184195_17	580332.Slit_1401	1.077e-105	347.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,2VHAQ@28216|Betaproteobacteria,44VIT@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
REGS1_k127_1184195_5	1485544.JQKP01000017_gene636	6.628e-190	600.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,2VH7C@28216|Betaproteobacteria,44V56@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
REGS1_k127_1184195_23	580332.Slit_1403	6.19e-75	263.0	COG4255@1|root,COG4255@2|Bacteria,1RA9X@1224|Proteobacteria,2WGEF@28216|Betaproteobacteria,44VSA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PhosphMutase
REGS1_k127_1262515_4	1123368.AUIS01000006_gene624	2.126e-48	180.0	COG1600@1|root,COG1600@2|Bacteria,1MV1H@1224|Proteobacteria,1RMD9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queG	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
REGS1_k127_1262515_3	1485544.JQKP01000003_gene110	1.176e-61	222.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,2VSJY@28216|Betaproteobacteria,44VZJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
REGS1_k127_1262515_0	1485544.JQKP01000003_gene109	3.201e-168	541.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,2VHXN@28216|Betaproteobacteria,44V74@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3
REGS1_k127_1262515_2	1485544.JQKP01000002_gene1490	6.479e-84	282.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,2VN1I@28216|Betaproteobacteria,44VQ1@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
REGS1_k127_1262515_1	1485544.JQKP01000002_gene1489	3.633e-86	290.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,44V9Q@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
REGS1_k127_1288007_42	1122604.JONR01000009_gene2401	2.903e-34	133.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,1S076@1236|Gammaproteobacteria,1X9SG@135614|Xanthomonadales	135614|Xanthomonadales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_1288007_8	1485544.JQKP01000005_gene298	1.442e-190	599.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,2VISR@28216|Betaproteobacteria,44UZW@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
REGS1_k127_1288007_7	580332.Slit_1007	1.123e-198	623.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,2VIM2@28216|Betaproteobacteria,44VGK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
REGS1_k127_1288007_40	580332.Slit_1008	1.224e-41	154.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,2VU4W@28216|Betaproteobacteria,44VZX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
REGS1_k127_1288007_38	580332.Slit_1009	5.862e-48	174.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,2VSHZ@28216|Betaproteobacteria,44VX7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
REGS1_k127_1288007_16	580332.Slit_2458	1.065e-158	519.0	COG0554@1|root,COG0554@2|Bacteria,1MUP7@1224|Proteobacteria,2VICH@28216|Betaproteobacteria	28216|Betaproteobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
REGS1_k127_1288007_29	859657.RPSI07_2718	4.206e-98	334.0	COG4269@1|root,COG4269@2|Bacteria,1MW5P@1224|Proteobacteria,2VMS5@28216|Betaproteobacteria,1K3TH@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF898)	-	-	-	-	-	-	-	-	-	-	-	-	DUF898
REGS1_k127_1288007_34	1123261.AXDW01000001_gene1393	8.385e-75	263.0	COG0501@1|root,COG0501@2|Bacteria,1NK9F@1224|Proteobacteria,1S4XC@1236|Gammaproteobacteria,1X548@135614|Xanthomonadales	135614|Xanthomonadales	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_1288007_23	1304883.KI912532_gene2366	1.574e-121	398.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,2VHW4@28216|Betaproteobacteria,2KURW@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	-	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
REGS1_k127_1288007_39	748247.AZKH_0068	1.231e-42	164.0	COG0746@1|root,COG0746@2|Bacteria,1RH3M@1224|Proteobacteria,2VQR2@28216|Betaproteobacteria,2KW8P@206389|Rhodocyclales	206389|Rhodocyclales	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
REGS1_k127_1288007_31	292415.Tbd_2143	1.173e-86	289.0	COG0521@1|root,COG0521@2|Bacteria,1R9W2@1224|Proteobacteria,2VH28@28216|Betaproteobacteria,1KRNC@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Probable molybdopterin binding domain	-	-	2.7.7.75	ko:K03831	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09726	RC00002	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth
REGS1_k127_1288007_35	497321.C664_03465	2.972e-68	238.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2WEW6@28216|Betaproteobacteria,2KZVC@206389|Rhodocyclales	206389|Rhodocyclales	K	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_1288007_36	1288494.EBAPG3_3540	9.536e-66	229.0	COG2353@1|root,COG2353@2|Bacteria,1R9XD@1224|Proteobacteria,2VQTQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0312 family	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
REGS1_k127_1288007_20	580332.Slit_2050	2.932e-136	441.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,2VIVB@28216|Betaproteobacteria,44VBA@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
REGS1_k127_1288007_33	1485544.JQKP01000003_gene104	1.272e-80	292.0	COG2853@1|root,COG2853@2|Bacteria,1MVX0@1224|Proteobacteria,2VQ97@28216|Betaproteobacteria,44VPX@713636|Nitrosomonadales	28216|Betaproteobacteria	M	MlaA lipoprotein	vacJ	-	-	ko:K04754	-	-	-	-	ko00000	-	-	-	MlaA
REGS1_k127_1288007_0	580332.Slit_2048	4.547e-282	884.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VMQU@28216|Betaproteobacteria	28216|Betaproteobacteria	T	CHASE2	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_1288007_41	580332.Slit_2047	2.581e-39	151.0	COG3103@1|root,COG3103@2|Bacteria,1N6AX@1224|Proteobacteria,2VVME@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
REGS1_k127_1288007_24	580332.Slit_2046	3.961e-121	396.0	COG4784@1|root,COG4784@2|Bacteria,1QXTD@1224|Proteobacteria,2WHJ6@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_1288007_30	580332.Slit_2040	2.386e-93	308.0	COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,44VSH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Nudix N-terminal	nudC_1	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N_2
REGS1_k127_1288007_32	1485544.JQKP01000003_gene106	2.28e-86	293.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,2VH6I@28216|Betaproteobacteria,44V65@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
REGS1_k127_1288007_19	1485544.JQKP01000003_gene107	5.081e-138	448.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,2VIFF@28216|Betaproteobacteria,44V1W@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_1288007_27	1485544.JQKP01000003_gene108	2.146e-107	352.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,2VKD4@28216|Betaproteobacteria,44VHJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
REGS1_k127_1288007_43	580332.Slit_2053	3.195e-30	126.0	COG1555@1|root,COG1555@2|Bacteria,1N6Q3@1224|Proteobacteria,2VVT0@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Competence protein	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3
REGS1_k127_1288007_13	580332.Slit_1172	1.124e-171	541.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VH7B@28216|Betaproteobacteria,44VI4@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.47	ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03132,R03601,R04859	RC00020,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_1288007_28	580332.Slit_1173	2.504e-98	341.0	28HEC@1|root,2Z7QS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1288007_1	395494.Galf_2104	8.522e-241	749.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,2VI16@28216|Betaproteobacteria,44V4G@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_1288007_11	580332.Slit_1372	2.471e-178	561.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,2VJ5G@28216|Betaproteobacteria,44VI3@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyl transferase family 2	arnC	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
REGS1_k127_1288007_14	580332.Slit_1373	3.974e-167	530.0	COG0223@1|root,COG0223@2|Bacteria,1MWH1@1224|Proteobacteria,2VKAI@28216|Betaproteobacteria,44VNB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Formyl transferase, C-terminal domain	pmrIa	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
REGS1_k127_1288007_2	580332.Slit_1374	1.696e-223	694.0	COG0451@1|root,COG0451@2|Bacteria,1MXKV@1224|Proteobacteria,2VJV2@28216|Betaproteobacteria,44UZQ@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	pmrIb	-	-	-	-	-	-	-	-	-	-	-	Epimerase
REGS1_k127_1288007_17	580332.Slit_1375	9.153e-154	490.0	COG0726@1|root,COG0726@2|Bacteria,1N8Q4@1224|Proteobacteria,2VKEP@28216|Betaproteobacteria,44VD4@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Polysaccharide deacetylase	arnD	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_1288007_18	1163617.SCD_n01102	8.281e-145	482.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,2WGU7@28216|Betaproteobacteria	28216|Betaproteobacteria	P	TonB-dependent Receptor Plug	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
REGS1_k127_1288007_44	1163617.SCD_n01101	1.861e-29	124.0	2E3CB@1|root,32YBM@2|Bacteria,1N6WD@1224|Proteobacteria,2VVST@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
REGS1_k127_1288007_9	1163617.SCD_n01100	1.032e-180	588.0	COG2972@1|root,COG5001@1|root,COG2972@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VKCJ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Periplasmic sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE8,EAL,GGDEF,HAMP
REGS1_k127_1288007_5	1123487.KB892838_gene3814	1.269e-207	653.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,2VGZI@28216|Betaproteobacteria,2KUMY@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
REGS1_k127_1288007_12	580332.Slit_1435	7.712e-172	552.0	COG1232@1|root,COG1232@2|Bacteria,1NQUH@1224|Proteobacteria,2VJV1@28216|Betaproteobacteria,44V02@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin containing amine oxidoreductase	hpnE	-	1.17.8.1	ko:K21677	-	-	-	-	ko00000,ko01000	-	-	-	Amino_oxidase
REGS1_k127_1288007_25	1120999.JONM01000005_gene3774	1.373e-115	380.0	COG1562@1|root,COG1562@2|Bacteria,1MX4W@1224|Proteobacteria,2VJ13@28216|Betaproteobacteria,2KPBY@206351|Neisseriales	206351|Neisseriales	I	Squalene synthase HpnD	hpnD	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
REGS1_k127_1288007_22	1485544.JQKP01000017_gene610	8.013e-130	425.0	COG1562@1|root,COG1562@2|Bacteria,1N6J2@1224|Proteobacteria,2VIZC@28216|Betaproteobacteria,44VE7@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Squalene/phytoene synthase	hpnC	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
REGS1_k127_1288007_21	1123393.KB891327_gene488	7.786e-135	435.0	COG2890@1|root,COG2890@2|Bacteria,1MX8Q@1224|Proteobacteria,2VIPK@28216|Betaproteobacteria,1KRF3@119069|Hydrogenophilales	119069|Hydrogenophilales	J	RNA cap guanine-N2 methyltransferase	-	-	2.1.1.298	ko:K07320	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03009	-	-	-	MTS
REGS1_k127_1288007_6	580332.Slit_1439	5.668e-207	648.0	COG0624@1|root,COG0624@2|Bacteria,1MW6G@1224|Proteobacteria,2VHRF@28216|Betaproteobacteria,44VKT@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls	dapE	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_1288007_37	580332.Slit_1440	2.216e-53	190.0	COG1393@1|root,COG1393@2|Bacteria,1MZ6S@1224|Proteobacteria,2VUB7@28216|Betaproteobacteria,44W1U@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ArsC family	yffB	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC
REGS1_k127_1288007_10	580332.Slit_1441	3.981e-179	568.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VHU7@28216|Betaproteobacteria,44W5Q@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	pilT2	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_1288007_15	1485544.JQKP01000017_gene614	6.855e-163	516.0	COG2171@1|root,COG2171@2|Bacteria,1MU0Y@1224|Proteobacteria,2VHUX@28216|Betaproteobacteria,44VFW@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
REGS1_k127_1288007_3	1485544.JQKP01000004_gene531	2.734e-211	661.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,2VIEP@28216|Betaproteobacteria,44VP4@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	dapC	-	2.6.1.17	ko:K14267	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04475	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_1288007_26	1485544.JQKP01000004_gene530	2.823e-108	358.0	COG0697@1|root,COG0697@2|Bacteria,1RBFV@1224|Proteobacteria,2VQEZ@28216|Betaproteobacteria,44VH6@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_1288007_4	580332.Slit_1452	6.666e-210	657.0	COG0027@1|root,COG0027@2|Bacteria,1N3KA@1224|Proteobacteria,2VH4M@28216|Betaproteobacteria,44VEC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate	purT	-	2.1.2.2	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp,Epimerase
REGS1_k127_1306993_12	633131.TR2A62_1584	2.214e-69	247.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,2TR2B@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Sel1 domain protein repeat-containing protein	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
REGS1_k127_1306993_3	395494.Galf_1388	9.416e-183	583.0	COG1109@1|root,COG1109@2|Bacteria,1MUB3@1224|Proteobacteria,2W82C@28216|Betaproteobacteria,44WB5@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_1306993_9	273121.WS1803	9.348e-93	319.0	COG3842@1|root,COG3842@2|Bacteria,1RC3N@1224|Proteobacteria,42MSG@68525|delta/epsilon subdivisions,2YMX7@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	E	ATP-binding protein	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
REGS1_k127_1306993_8	1095769.CAHF01000006_gene1733	1.506e-95	317.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,2VIZW@28216|Betaproteobacteria,4731K@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
REGS1_k127_1306993_20	653733.Selin_1853	8.925e-35	139.0	COG4148@1|root,COG4148@2|Bacteria	2|Bacteria	P	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system	modE	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,HTH_17,TOBE
REGS1_k127_1306993_26	1122236.KB905142_gene387	1.708e-05	52.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,2KN5C@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
REGS1_k127_1306993_1	580332.Slit_0663	2.112e-227	751.0	COG4191@1|root,COG5001@1|root,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9,dCache_2
REGS1_k127_1306993_5	1454004.AW11_02129	7.597e-167	532.0	COG0477@1|root,COG2814@2|Bacteria,1MXPM@1224|Proteobacteria,2VHXT@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
REGS1_k127_1306993_17	1485544.JQKP01000001_gene971	4.908e-46	170.0	COG0791@1|root,COG0791@2|Bacteria,1N0EE@1224|Proteobacteria,2VSHN@28216|Betaproteobacteria,44VY3@713636|Nitrosomonadales	28216|Betaproteobacteria	M	NlpC/P60 family	-	-	-	ko:K19303	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
REGS1_k127_1306993_6	580332.Slit_2674	8.331e-116	381.0	COG2951@1|root,COG2951@2|Bacteria,1MUZ3@1224|Proteobacteria,2VJGZ@28216|Betaproteobacteria,44VFF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transglycosylase SLT domain	mltB	-	-	ko:K08305	-	-	-	-	ko00000,ko01000,ko01011	-	GH103	-	SLT_2
REGS1_k127_1306993_4	580332.Slit_2675	1.299e-178	565.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,2VIVV@28216|Betaproteobacteria,44VC9@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_1306993_16	580332.Slit_2676	1.121e-53	196.0	COG2840@1|root,COG2840@2|Bacteria,1RH34@1224|Proteobacteria,2VQ2S@28216|Betaproteobacteria,44VZ1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Smr domain	smrA	-	-	-	-	-	-	-	-	-	-	-	Smr
REGS1_k127_1306993_2	1123354.AUDR01000015_gene349	2.588e-200	633.0	COG1488@1|root,COG1488@2|Bacteria,1PNWY@1224|Proteobacteria,2W9DN@28216|Betaproteobacteria,1KS4Z@119069|Hydrogenophilales	119069|Hydrogenophilales	H	Nicotinate phosphoribosyltransferase (NAPRTase) family	-	-	-	-	-	-	-	-	-	-	-	-	NAPRTase
REGS1_k127_1306993_11	748247.AZKH_2793	6.66e-78	267.0	COG1335@1|root,COG1335@2|Bacteria,1MUGW@1224|Proteobacteria,2VIMK@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Nicotinamidase	pncA	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
REGS1_k127_1306993_22	1132855.KB913035_gene1185	2.741e-14	79.0	2FJZ4@1|root,34BMG@2|Bacteria,1P0NJ@1224|Proteobacteria,2W405@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1306993_10	1168067.JAGP01000001_gene837	7.642e-90	304.0	COG2199@1|root,COG3706@2|Bacteria,1QVPY@1224|Proteobacteria,1T2GE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K13069	-	-	R08057	-	ko00000,ko01000	-	-	-	CZB,GGDEF
REGS1_k127_1306993_0	580332.Slit_1196	4.339e-287	903.0	COG1067@1|root,COG1067@2|Bacteria,1MWGB@1224|Proteobacteria,2VJ54@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_32,Lon_C
REGS1_k127_1306993_13	261292.Nit79A3_2912	1.439e-67	238.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,37347@32003|Nitrosomonadales	28216|Betaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1306993_14	395494.Galf_0044	1.88e-57	205.0	COG1499@1|root,COG1499@2|Bacteria,1RD49@1224|Proteobacteria,2VRQB@28216|Betaproteobacteria,44WFC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	ribosomal large subunit export from nucleus	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1306993_7	580332.Slit_0602	5.985e-110	376.0	COG0457@1|root,COG0500@1|root,COG4976@1|root,COG0457@2|Bacteria,COG2226@2|Bacteria,COG4976@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,44WAR@713636|Nitrosomonadales	28216|Betaproteobacteria	O	repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_8
REGS1_k127_1306993_15	1122236.KB905141_gene1471	6.612e-57	199.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,2KMZX@206350|Nitrosomonadales	206350|Nitrosomonadales	K	Belongs to the P(II) protein family	-	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
REGS1_k127_1306993_21	580332.Slit_1740	5.938e-21	102.0	COG0457@1|root,COG0457@2|Bacteria,1P9X0@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1306993_18	316067.Geob_2685	4.053e-45	175.0	COG1463@1|root,COG1463@2|Bacteria,1PP5M@1224|Proteobacteria,42X77@68525|delta/epsilon subdivisions	1224|Proteobacteria	Q	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
REGS1_k127_1306993_23	580332.Slit_1742	1.193e-08	65.0	COG1127@1|root,COG1127@2|Bacteria,1P91Q@1224|Proteobacteria	1224|Proteobacteria	Q	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1306993_19	316067.Geob_2687	1.68e-44	171.0	COG0767@1|root,COG0767@2|Bacteria,1N2HV@1224|Proteobacteria,42UV1@68525|delta/epsilon subdivisions,2WQXM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
REGS1_k127_1319177_2	883078.HMPREF9695_02588	4.207e-50	187.0	COG0846@1|root,COG0846@2|Bacteria	2|Bacteria	K	NAD+ binding	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
REGS1_k127_1319177_3	580332.Slit_0538	7.342e-10	67.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,44W47@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
REGS1_k127_1319177_4	666681.M301_0865	1.038e-08	62.0	2BKHD@1|root,2ZGSD@2|Bacteria,1P4ZX@1224|Proteobacteria,2W55F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1319177_0	395494.Galf_0669	2.097e-171	543.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,44VGY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the radical SAM superfamily. RlmN family	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
REGS1_k127_1319177_1	580332.Slit_2201	2.411e-91	309.0	COG0349@1|root,COG0349@2|Bacteria,1REMB@1224|Proteobacteria,2VQQC@28216|Betaproteobacteria,44WFH@713636|Nitrosomonadales	28216|Betaproteobacteria	L	3'-5' exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DNA_pol_A_exo1
REGS1_k127_1341329_8	1034807.FBFL15_1254	3.651e-09	59.0	2EGH2@1|root,33A95@2|Bacteria,4NWV7@976|Bacteroidetes,1I5F5@117743|Flavobacteriia,2NXVC@237|Flavobacterium	976|Bacteroidetes	S	Domain of unknown function (DUF4375)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4375
REGS1_k127_1341329_4	96561.Dole_3083	1.871e-103	345.0	COG0596@1|root,COG0596@2|Bacteria,1QVQ5@1224|Proteobacteria,43BS7@68525|delta/epsilon subdivisions,2X730@28221|Deltaproteobacteria,2MM0E@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
REGS1_k127_1341329_7	880071.Fleli_3107	8.547e-53	191.0	2BWR5@1|root,2ZUVQ@2|Bacteria,4P955@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1341329_1	1163617.SCD_n01977	3.106e-137	447.0	COG0686@1|root,COG0686@2|Bacteria,1QTX1@1224|Proteobacteria,2VHD1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
REGS1_k127_1341329_0	1485544.JQKP01000012_gene2112	6.034e-158	503.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,2VJ6H@28216|Betaproteobacteria,44VPF@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
REGS1_k127_1341329_6	76114.ebA4890	5.616e-98	325.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,2VJ8E@28216|Betaproteobacteria,2KVBA@206389|Rhodocyclales	206389|Rhodocyclales	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
REGS1_k127_1341329_3	580332.Slit_2384	3.678e-113	370.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,2VIUV@28216|Betaproteobacteria,44VGV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
REGS1_k127_1341329_2	580332.Slit_2383	2.435e-113	384.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1341329_5	580332.Slit_2382	5.578e-98	326.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VJ6G@28216|Betaproteobacteria,44VRU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	estB	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
REGS1_k127_1428480_4	580332.Slit_0487	2.45e-16	82.0	2FAB0@1|root,342JM@2|Bacteria,1NYGK@1224|Proteobacteria,2W3RC@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1428480_2	1121035.AUCH01000014_gene2353	5.052e-53	204.0	COG1729@1|root,COG1729@2|Bacteria,1QU1J@1224|Proteobacteria,2VPHK@28216|Betaproteobacteria,2KYPR@206389|Rhodocyclales	206389|Rhodocyclales	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1428480_0	580332.Slit_0124	4.91e-68	236.0	28HPC@1|root,2Z7XD@2|Bacteria,1REIX@1224|Proteobacteria,2VS60@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4337)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4337
REGS1_k127_1428480_1	1123487.KB892867_gene1020	3.892e-55	202.0	2DN3C@1|root,32VAC@2|Bacteria,1QY3X@1224|Proteobacteria,2WHB1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1428480_3	1219084.AP014508_gene1276	2.186e-29	123.0	COG2110@1|root,COG2110@2|Bacteria,2GD2K@200918|Thermotogae	200918|Thermotogae	S	PFAM Appr-1-p processing domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Macro
REGS1_k127_1451890_7	580332.Slit_2208	1.745e-99	327.0	COG2230@1|root,COG2230@2|Bacteria,1QXKQ@1224|Proteobacteria,2WHPJ@28216|Betaproteobacteria,44VP5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
REGS1_k127_1451890_0	580332.Slit_0934	0.0	1602.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44VNU@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_1451890_6	580332.Slit_0933	1.639e-121	399.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,2VIDH@28216|Betaproteobacteria,44WFA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_1451890_5	395494.Galf_1818	6.055e-148	472.0	COG0679@1|root,COG0679@2|Bacteria,1PHSS@1224|Proteobacteria,2VSSE@28216|Betaproteobacteria,44V9Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
REGS1_k127_1451890_1	580332.Slit_2217	4.154e-276	852.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2VHR6@28216|Betaproteobacteria,44VFM@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Threonine synthase N terminus	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
REGS1_k127_1451890_10	500153.JOEK01000001_gene4120	3.235e-11	68.0	COG0662@1|root,COG0662@2|Bacteria,2INXJ@201174|Actinobacteria	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_1451890_3	1485544.JQKP01000001_gene1301	3.021e-242	752.0	COG0460@1|root,COG0460@2|Bacteria,1MUDC@1224|Proteobacteria,2VH9T@28216|Betaproteobacteria,44V4Q@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
REGS1_k127_1451890_2	580332.Slit_2219	6.887e-251	776.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VH4Z@28216|Betaproteobacteria,44V1P@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	alaA	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_1451890_9	580332.Slit_2220	1.005e-38	148.0	COG3737@1|root,COG3737@2|Bacteria,1N083@1224|Proteobacteria,2VUF2@28216|Betaproteobacteria,44VYU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF498/DUF598)	-	-	-	-	-	-	-	-	-	-	-	-	DUF498
REGS1_k127_1451890_4	580332.Slit_2221	1.777e-164	520.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,44WCC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ATPase associated with various cellular activities AAA_3	moxR	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
REGS1_k127_1451890_8	580332.Slit_2222	3.789e-48	176.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria,44WBQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_1619370_12	498761.HM1_1228	3.915e-38	154.0	COG1216@1|root,COG1216@2|Bacteria,1VBEV@1239|Firmicutes,24XNE@186801|Clostridia	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_1619370_9	592029.DDD_2281	2.253e-75	263.0	COG1216@1|root,COG1216@2|Bacteria,4NIW6@976|Bacteroidetes,1IK7C@117743|Flavobacteriia	976|Bacteroidetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_1619370_10	857087.Metme_1189	8.045e-64	227.0	COG0030@1|root,COG0030@2|Bacteria	2|Bacteria	J	rRNA (adenine-N6,N6-)-dimethyltransferase activity	ksgA	-	2.1.1.182,2.1.1.184	ko:K00561,ko:K02528	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	Methyltransf_21,RrnaAD
REGS1_k127_1619370_11	90814.KL370891_gene411	1.439e-60	220.0	COG1216@1|root,COG1216@2|Bacteria,1RAIR@1224|Proteobacteria,1S6AX@1236|Gammaproteobacteria,461RU@72273|Thiotrichales	72273|Thiotrichales	S	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_1619370_1	1504672.669785732	1.386e-186	596.0	COG2244@1|root,COG2244@2|Bacteria,1MXWW@1224|Proteobacteria,2VNZP@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pfam Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
REGS1_k127_1619370_13	32057.KB217478_gene3297	2.389e-33	138.0	COG4627@1|root,COG4627@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
REGS1_k127_1619370_7	506534.Rhein_1694	3.17e-125	404.0	COG2227@1|root,COG2227@2|Bacteria,1R5UC@1224|Proteobacteria,1RUM4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
REGS1_k127_1619370_14	351016.RAZWK3B_05802	2.855e-19	96.0	COG0454@1|root,COG0456@2|Bacteria,1NJBH@1224|Proteobacteria,2UZ6N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
REGS1_k127_1619370_4	909663.KI867150_gene1735	7.308e-140	456.0	COG1621@1|root,COG1621@2|Bacteria,1PPCS@1224|Proteobacteria,430SX@68525|delta/epsilon subdivisions,2WWA6@28221|Deltaproteobacteria	2|Bacteria	G	beta-fructofuranosidase activity	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32N
REGS1_k127_1619370_3	561230.PC1_2566	9.49e-164	519.0	COG1621@1|root,COG1621@2|Bacteria,1N5AZ@1224|Proteobacteria,1T04N@1236|Gammaproteobacteria,1MT6T@122277|Pectobacterium	1236|Gammaproteobacteria	G	beta-fructofuranosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1619370_8	936455.KI421499_gene1461	9.91e-96	322.0	COG4122@1|root,COG4122@2|Bacteria,1NIE0@1224|Proteobacteria,2UC4D@28211|Alphaproteobacteria,3K2PA@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	WbqC-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	WbqC
REGS1_k127_1619370_0	1123393.KB891333_gene2611	4.384e-199	624.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJIY@28216|Betaproteobacteria,1KS9I@119069|Hydrogenophilales	119069|Hydrogenophilales	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_1619370_6	1485544.JQKP01000002_gene1539	1.678e-125	410.0	COG0859@1|root,COG0859@2|Bacteria,1MYZA@1224|Proteobacteria,2VPK7@28216|Betaproteobacteria,44WH1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaC	-	-	ko:K02841	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
REGS1_k127_1619370_2	1485544.JQKP01000002_gene1540	1.79e-170	546.0	COG1519@1|root,COG1519@2|Bacteria,1MU9F@1224|Proteobacteria,2VI67@28216|Betaproteobacteria,44VI0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	kdtA	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_1,Glycos_transf_N
REGS1_k127_1619370_5	1485545.JQLW01000010_gene1667	3.293e-135	437.0	COG0685@1|root,COG0685@2|Bacteria,1QGEE@1224|Proteobacteria	1224|Proteobacteria	E	reductase	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR
REGS1_k127_1619370_15	1123393.KB891316_gene1084	6.293e-11	64.0	COG1091@1|root,COG1091@2|Bacteria,1MUXM@1224|Proteobacteria,2VI50@28216|Betaproteobacteria,1KRNB@119069|Hydrogenophilales	119069|Hydrogenophilales	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
REGS1_k127_1623888_1	580332.Slit_1803	7.161e-62	214.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,44V8T@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
REGS1_k127_1623888_0	580332.Slit_1802	0.0	1392.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,2VIAU@28216|Betaproteobacteria,44VGG@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
REGS1_k127_1623888_2	1123393.KB891329_gene993	3.478e-40	151.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VU4V@28216|Betaproteobacteria,1KTB5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
REGS1_k127_1623888_3	202952.BBLI01000004_gene491	1.406e-17	84.0	2DR59@1|root,33A7S@2|Bacteria,1NMH2@1224|Proteobacteria,1SIVW@1236|Gammaproteobacteria,3NS87@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1623888_4	292.DM42_2880	1.101e-10	72.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_5,Phage_integrase
REGS1_k127_1656034_0	999541.bgla_1g31480	9.657e-130	436.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,2VH64@28216|Betaproteobacteria,1K0NI@119060|Burkholderiaceae	28216|Betaproteobacteria	H	receptor	btuB	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
REGS1_k127_1656034_4	395494.Galf_0311	2.488e-14	74.0	2EG8X@1|root,33A0Q@2|Bacteria,1NMVN@1224|Proteobacteria,2VY0V@28216|Betaproteobacteria,44W3H@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1656034_3	580332.Slit_2683	3.174e-48	174.0	COG3027@1|root,COG3027@2|Bacteria,1N6YN@1224|Proteobacteria,2VUY2@28216|Betaproteobacteria,44VZ2@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division protein ZapA	zapA	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
REGS1_k127_1656034_1	580332.Slit_2684	5.453e-86	287.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,2VRIB@28216|Betaproteobacteria,44VRP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
REGS1_k127_1656034_2	580332.Slit_2685	2.592e-56	203.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,44V3G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
REGS1_k127_172970_19	580332.Slit_0638	1.957e-81	279.0	2AG1B@1|root,3165E@2|Bacteria,1PWWQ@1224|Proteobacteria,2WCF3@28216|Betaproteobacteria,44VY6@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_172970_13	580332.Slit_0639	1.419e-109	357.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,2VQNT@28216|Betaproteobacteria,44W8I@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
REGS1_k127_172970_11	580332.Slit_0640	7.555e-117	378.0	COG2010@1|root,COG2010@2|Bacteria,1P88Q@1224|Proteobacteria,2W4CG@28216|Betaproteobacteria,44VXH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_172970_0	580332.Slit_0641	0.0	1195.0	COG0243@1|root,COG0243@2|Bacteria,1P01N@1224|Proteobacteria,2VKSY@28216|Betaproteobacteria,44V4I@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
REGS1_k127_172970_8	580332.Slit_0642	8.957e-171	538.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44V6V@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11,Fer4_7
REGS1_k127_172970_1	580332.Slit_0643	1.13e-288	888.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,2VWU7@28216|Betaproteobacteria,44VHA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
REGS1_k127_172970_17	580332.Slit_0644	9.045e-92	303.0	2DSXF@1|root,33HTI@2|Bacteria,1NHAS@1224|Proteobacteria,2WCC6@28216|Betaproteobacteria,44VSE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
REGS1_k127_172970_18	580332.Slit_0645	1.573e-88	296.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria,2WCCQ@28216|Betaproteobacteria,44VT7@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
REGS1_k127_172970_7	580332.Slit_0646	1.095e-174	554.0	COG5557@1|root,COG5557@2|Bacteria,1QZY1@1224|Proteobacteria,2W53W@28216|Betaproteobacteria,44V2N@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Pfam Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_172970_12	580332.Slit_0647	1.477e-111	362.0	COG0625@1|root,COG0625@2|Bacteria,1MXJD@1224|Proteobacteria,2VIAW@28216|Betaproteobacteria,44VQB@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	sspA	-	-	ko:K03599	-	-	-	-	ko00000,ko02000,ko03021	1.A.12.3.1	-	-	GST_C,GST_C_2,GST_N,GST_N_3
REGS1_k127_172970_23	580332.Slit_0648	5.194e-44	166.0	COG2969@1|root,COG2969@2|Bacteria,1MZ2Q@1224|Proteobacteria,2VSGG@28216|Betaproteobacteria,44W0U@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Stringent starvation protein B	sspB	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
REGS1_k127_172970_20	1000565.METUNv1_03838	9.151e-81	285.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria,2KU89@206389|Rhodocyclales	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_172970_29	580332.Slit_2376	1.509e-16	80.0	2BJRY@1|root,32E3Z@2|Bacteria,1QDFM@1224|Proteobacteria,2W89G@28216|Betaproteobacteria,44WMT@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_172970_14	1485544.JQKP01000012_gene2149	2.854e-103	340.0	COG0476@1|root,COG0476@2|Bacteria,1MW7H@1224|Proteobacteria,2VI1U@28216|Betaproteobacteria,44UZK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM UBA THIF-type NAD FAD binding protein	thiF	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
REGS1_k127_172970_24	1485544.JQKP01000012_gene2148	1.086e-41	158.0	2BG6F@1|root,32A39@2|Bacteria,1RI4Y@1224|Proteobacteria,2VT9E@28216|Betaproteobacteria,44W2C@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_172970_3	1485544.JQKP01000012_gene2147	2.233e-219	688.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VJ86@28216|Betaproteobacteria,44VD5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
REGS1_k127_172970_9	580332.Slit_2621	1.559e-129	425.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,2VIV9@28216|Betaproteobacteria,44VHE@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidase family M23	envC	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_172970_2	580332.Slit_2620	2.007e-259	806.0	COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,2VMTN@28216|Betaproteobacteria,44V6E@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
REGS1_k127_172970_25	395494.Galf_0213	1.67e-41	154.0	COG0640@1|root,COG0640@2|Bacteria,1N72Q@1224|Proteobacteria,2VU9V@28216|Betaproteobacteria,44VY1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	bigR	-	-	-	-	-	-	-	-	-	-	-	HTH_5
REGS1_k127_172970_27	1485544.JQKP01000002_gene1636	5.356e-35	140.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,2VWDY@28216|Betaproteobacteria,44VYI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
REGS1_k127_172970_26	580332.Slit_2756	2.48e-38	152.0	COG0762@1|root,COG0762@2|Bacteria,1RCZV@1224|Proteobacteria,2VRHV@28216|Betaproteobacteria,44VT3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YGGT family	-	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
REGS1_k127_172970_21	1485544.JQKP01000002_gene1638	4.281e-78	274.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,2VJD1@28216|Betaproteobacteria,44V7F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
REGS1_k127_172970_15	580332.Slit_2758	2.385e-98	327.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,2VHNY@28216|Betaproteobacteria,44V25@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
REGS1_k127_172970_5	580332.Slit_2759	5.478e-205	641.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,2VHHW@28216|Betaproteobacteria,44V93@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	pilT	-	-	ko:K02669,ko:K12203	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2,3.A.7.10.1,3.A.7.9.1	-	-	T2SSE
REGS1_k127_172970_4	580332.Slit_2760	1.654e-215	674.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,44V5T@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_172970_16	1217714.F975_00075	5.904e-92	324.0	COG2206@1|root,COG3290@1|root,COG2206@2|Bacteria,COG3290@2|Bacteria,1QXG8@1224|Proteobacteria,1T4ZU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Membrane-associated sensor domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,MASE3,PAS,PAS_9
REGS1_k127_172970_6	1485544.JQKP01000002_gene1642	4.914e-186	587.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,2VHMY@28216|Betaproteobacteria,44UYX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	THUMP	rlmL	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
REGS1_k127_172970_22	640081.Dsui_0607	6.434e-53	192.0	COG1981@1|root,COG1981@2|Bacteria,1RHGS@1224|Proteobacteria,2VR5Y@28216|Betaproteobacteria,2KWBC@206389|Rhodocyclales	206389|Rhodocyclales	S	membrane	-	-	-	ko:K08973	-	-	-	-	ko00000	-	-	-	UPF0093
REGS1_k127_172970_10	580332.Slit_2816	5.195e-123	398.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,44W6T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC-2 type transporter	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
REGS1_k127_172970_28	580332.Slit_2817	1.539e-22	98.0	COG0824@1|root,COG0824@2|Bacteria,1RCSP@1224|Proteobacteria,2VXA8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
REGS1_k127_1773372_2	640081.Dsui_0954	2.007e-98	329.0	28IJT@1|root,2Z8KN@2|Bacteria,1R6VB@1224|Proteobacteria,2VJQS@28216|Betaproteobacteria,2KW0T@206389|Rhodocyclales	206389|Rhodocyclales	H	Dinitrogenase reductase ADP-ribosyltransferase (DRAT)	draT	-	2.4.2.37	ko:K05951	-	-	-	-	ko00000,ko01000	-	-	-	DRAT
REGS1_k127_1773372_0	1134912.AJTV01000014_gene281	4.944e-255	791.0	COG1251@1|root,COG2710@1|root,COG1251@2|Bacteria,COG2710@2|Bacteria,1MWAJ@1224|Proteobacteria,2TQUV@28211|Alphaproteobacteria,36ZI6@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifE	-	-	ko:K02587	-	-	-	-	ko00000	-	-	-	Fer2_BFD,Oxidored_nitro
REGS1_k127_1773372_1	1134912.AJTV01000014_gene282	1.268e-197	628.0	COG2710@1|root,COG2710@2|Bacteria,1MWSX@1224|Proteobacteria,2TTNK@28211|Alphaproteobacteria,36X7J@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Nitrogenase component 1 type Oxidoreductase	nifN	-	-	ko:K02592	-	-	-	-	ko00000	-	-	-	Oxidored_nitro
REGS1_k127_1773372_3	187303.BN69_2628	3.226e-64	224.0	COG1433@1|root,COG1433@2|Bacteria,1RD9P@1224|Proteobacteria,2U9AX@28211|Alphaproteobacteria,36YQA@31993|Methylocystaceae	28211|Alphaproteobacteria	S	Dinitrogenase iron-molybdenum cofactor	nifX	-	-	ko:K02596	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co
REGS1_k127_1773372_4	748247.AZKH_4084	4.809e-13	71.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,2VQYS@28216|Betaproteobacteria,2KWCX@206389|Rhodocyclales	206389|Rhodocyclales	S	Protein of unknown function, DUF269	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
REGS1_k127_1819999_2	580332.Slit_0293	9.851e-198	618.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,44VKQ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme formylation region	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
REGS1_k127_1819999_0	580332.Slit_0294	4.689e-247	766.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,2VH9J@28216|Betaproteobacteria,44V8B@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
REGS1_k127_1819999_3	1485544.JQKP01000002_gene1400	1.864e-79	269.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,44VTE@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate	tsaC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
REGS1_k127_1819999_1	580332.Slit_0296	2.79e-203	638.0	COG0408@1|root,COG0408@2|Bacteria,1MWMF@1224|Proteobacteria,2VIN4@28216|Betaproteobacteria,44VJH@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX	hemF	GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983	1.3.3.3	ko:K00228	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03220	RC00884	ko00000,ko00001,ko00002,ko01000	-	-	-	Coprogen_oxidas
REGS1_k127_1819999_4	580332.Slit_0051	1.385e-21	100.0	COG0840@1|root,COG0840@2|Bacteria,1NKHI@1224|Proteobacteria,2WHPN@28216|Betaproteobacteria,44W48@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Chemoreceptor zinc-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CZB
REGS1_k127_1863163_8	1122134.KB893650_gene390	1.566e-22	109.0	2C4GG@1|root,331DQ@2|Bacteria,1N7QC@1224|Proteobacteria,1SCI3@1236|Gammaproteobacteria,1XM9B@135619|Oceanospirillales	135619|Oceanospirillales	S	Polyribonucleotide nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1863163_5	159087.Daro_2916	1.745e-35	139.0	COG0759@1|root,COG0759@2|Bacteria,1Q3VC@1224|Proteobacteria,2VXQF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Haemolytic	-	-	-	-	-	-	-	-	-	-	-	-	Haemolytic
REGS1_k127_1863163_0	583345.Mmol_1448	1.967e-175	561.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,2VH8F@28216|Betaproteobacteria	28216|Betaproteobacteria	K	aminotransferase class I and II	ydcR_1	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
REGS1_k127_1863163_6	580332.Slit_2648	8.818e-32	129.0	28UDI@1|root,2ZGIM@2|Bacteria,1PBJI@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1863163_11	1387312.BAUS01000002_gene490	2.441e-05	53.0	COG3637@1|root,COG3637@2|Bacteria,1NIE3@1224|Proteobacteria,2VXMU@28216|Betaproteobacteria,2KNUS@206350|Nitrosomonadales	206350|Nitrosomonadales	M	OmpA-like transmembrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl
REGS1_k127_1863163_10	1156919.QWC_13397	1.04e-12	70.0	COG2200@1|root,COG2200@2|Bacteria,1N299@1224|Proteobacteria,2WGR2@28216|Betaproteobacteria,3T9K7@506|Alcaligenaceae	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3330,EAL,PTS_EIIC
REGS1_k127_1863163_1	1304878.AUGD01000002_gene1746	1.827e-64	230.0	28Q4M@1|root,2ZCMV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_1863163_2	62928.azo2660	2.338e-63	222.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,2VR39@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM PEBP family protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
REGS1_k127_1863163_3	398525.KB900701_gene1996	6.468e-57	210.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria,2TVU9@28211|Alphaproteobacteria,3JUSH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Ubie_methyltran
REGS1_k127_1863163_4	886293.Sinac_5702	1.903e-43	168.0	COG0705@1|root,COG0705@2|Bacteria,2IZJ7@203682|Planctomycetes	203682|Planctomycetes	S	Rhomboid family	-	-	-	ko:K02441	-	-	-	-	ko00000	-	-	-	Rhomboid,Rhomboid_N
REGS1_k127_1863163_7	557598.LHK_01537	1.493e-28	121.0	COG3375@1|root,COG3375@2|Bacteria	2|Bacteria	M	carboxylic acid catabolic process	-	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
REGS1_k127_1893872_19	1472716.KBK24_0123855	7.601e-24	104.0	COG0438@1|root,COG0438@2|Bacteria,1N0Z5@1224|Proteobacteria,2VRC8@28216|Betaproteobacteria,1K4W7@119060|Burkholderiaceae	28216|Betaproteobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_1893872_7	640081.Dsui_0060	2.34e-143	461.0	COG1089@1|root,COG1089@2|Bacteria,1Q6NV@1224|Proteobacteria,2VNPY@28216|Betaproteobacteria,2KYCQ@206389|Rhodocyclales	206389|Rhodocyclales	M	GDP-mannose 4,6 dehydratase	-	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
REGS1_k127_1893872_13	1499967.BAYZ01000063_gene6023	7.215e-65	229.0	COG2148@1|root,COG2148@2|Bacteria	2|Bacteria	M	undecaprenyl-phosphate glucose phosphotransferase activity	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
REGS1_k127_1893872_2	1163617.SCD_n02873	4.818e-245	771.0	COG1086@1|root,COG1086@2|Bacteria,1MWKY@1224|Proteobacteria,2VHGF@28216|Betaproteobacteria	28216|Betaproteobacteria	GM	Polysaccharide biosynthesis protein	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
REGS1_k127_1893872_11	1049564.TevJSym_bj00060	2.645e-94	315.0	COG1216@1|root,COG3307@1|root,COG1216@2|Bacteria,COG3307@2|Bacteria,1QU2Q@1224|Proteobacteria,1T1NF@1236|Gammaproteobacteria,1JC2J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Glycosyl transferase family 2	waaE	-	-	ko:K12984	-	-	-	-	ko00000,ko01000,ko01003,ko01005,ko02000	4.D.1.3	GT2	-	Glyco_transf_7C,Glycos_transf_2
REGS1_k127_1893872_10	344747.PM8797T_05845	4.084e-96	325.0	COG1216@1|root,COG1216@2|Bacteria,2IZF5@203682|Planctomycetes	203682|Planctomycetes	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_7C,Glycos_transf_2
REGS1_k127_1893872_5	580332.Slit_2876	9.178e-147	472.0	COG0438@1|root,COG0438@2|Bacteria,1PZ1U@1224|Proteobacteria,2WE5X@28216|Betaproteobacteria,44VHB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	ko:K02844	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
REGS1_k127_1893872_12	1038869.AXAN01000008_gene5104	7.581e-84	293.0	COG3307@1|root,COG3307@2|Bacteria,1R8PC@1224|Proteobacteria,2WERZ@28216|Betaproteobacteria,1KHU6@119060|Burkholderiaceae	28216|Betaproteobacteria	M	O-Antigen ligase	-	-	-	ko:K02847	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
REGS1_k127_1893872_3	580332.Slit_2874	2.265e-154	492.0	COG1216@1|root,COG1216@2|Bacteria,1MWWA@1224|Proteobacteria,2VP86@28216|Betaproteobacteria,44W7Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_1893872_15	1038869.AXAN01000036_gene2066	6.571e-47	183.0	COG4641@1|root,COG4641@2|Bacteria,1PF0D@1224|Proteobacteria,2W50C@28216|Betaproteobacteria,1KEW6@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
REGS1_k127_1893872_17	1485544.JQKP01000002_gene1525	5.323e-35	137.0	COG2246@1|root,COG2246@2|Bacteria,1NABJ@1224|Proteobacteria,2VZ1X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
REGS1_k127_1893872_4	580332.Slit_2871	8.854e-152	482.0	COG0639@1|root,COG0639@2|Bacteria,1MV10@1224|Proteobacteria,2VHV6@28216|Betaproteobacteria,44VCX@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP	apaH	-	3.6.1.41	ko:K01525	ko00230,map00230	-	R00125	RC00002	ko00000,ko00001,ko01000	-	-	-	Metallophos
REGS1_k127_1893872_14	84531.JMTZ01000021_gene3824	3.97e-54	197.0	COG1988@1|root,COG1988@2|Bacteria,1RBHW@1224|Proteobacteria,1S2F9@1236|Gammaproteobacteria,1X77S@135614|Xanthomonadales	135614|Xanthomonadales	S	LexA-binding, inner membrane-associated putative hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
REGS1_k127_1893872_16	580332.Slit_2870	1.508e-40	153.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,2VU4I@28216|Betaproteobacteria	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
REGS1_k127_1893872_18	748247.AZKH_0544	1.449e-32	139.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VV0X@28216|Betaproteobacteria,2KZUI@206389|Rhodocyclales	206389|Rhodocyclales	K	Cold shock protein domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_1893872_8	580332.Slit_0021	4.41e-142	456.0	COG0583@1|root,COG0583@2|Bacteria,1MWVU@1224|Proteobacteria,2VJJH@28216|Betaproteobacteria,44VAP@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LysR substrate binding domain	cbbR	-	-	ko:K21703	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
REGS1_k127_1893872_1	292415.Tbd_2638	7.835e-295	906.0	COG1850@1|root,COG1850@2|Bacteria,1MWEB@1224|Proteobacteria,2VJF4@28216|Betaproteobacteria	28216|Betaproteobacteria	H	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site	cbbM	-	4.1.1.39	ko:K01601	ko00630,ko00710,ko01100,ko01120,ko01200,map00630,map00710,map01100,map01120,map01200	M00165,M00166,M00532	R00024,R03140	RC00172,RC00859	ko00000,ko00001,ko00002,ko01000	-	-	-	RuBisCO_large,RuBisCO_large_N
REGS1_k127_1893872_6	580332.Slit_0023	5.331e-144	460.0	COG0714@1|root,COG0714@2|Bacteria,1MXIW@1224|Proteobacteria,2VHWI@28216|Betaproteobacteria,44UZJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ATPase associated with various cellular activities AAA_5	cbbQ2	-	-	ko:K04748	-	-	R00294	RC02794	ko00000	3.D.4.10	-	-	AAA_5,CbbQ_C
REGS1_k127_1893872_0	1163617.SCD_n02852	2.906e-299	935.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria	28216|Betaproteobacteria	P	von Willebrand factor, type A	cbbO2	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
REGS1_k127_1893872_9	580332.Slit_0025	3.475e-127	409.0	COG0158@1|root,COG0158@2|Bacteria,1MW0E@1224|Proteobacteria,2VIJT@28216|Betaproteobacteria,44V03@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Fructose-1-6-bisphosphatase, N-terminal domain	fbp	-	3.1.3.11	ko:K03841	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko04152,ko04910,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map04152,map04910	M00003,M00165,M00167,M00344	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FBPase
REGS1_k127_201891_1	580332.Slit_2388	1.065e-273	847.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2VH62@28216|Betaproteobacteria,44VAQ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Integral membrane sensor signal transduction histidine kinase	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD
REGS1_k127_201891_3	1348657.M622_04875	7.868e-82	278.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,2KUZU@206389|Rhodocyclales	206389|Rhodocyclales	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_201891_0	580332.Slit_2390	0.0	1023.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,44VF3@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
REGS1_k127_201891_2	159087.Daro_1184	1.368e-261	820.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,2KUQJ@206389|Rhodocyclales	206389|Rhodocyclales	P	Transport of potassium into the cell	-	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
REGS1_k127_201891_4	1095769.CAHF01000025_gene689	1.806e-09	60.0	2AHNZ@1|root,31810@2|Bacteria,1PZMC@1224|Proteobacteria,2WCP4@28216|Betaproteobacteria,477ZF@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2036184_2	1485544.JQKP01000001_gene1085	3.315e-98	329.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,44VA5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_2036184_0	580332.Slit_0324	6.109e-127	409.0	COG0496@1|root,COG0496@2|Bacteria,1MVHE@1224|Proteobacteria,2VIND@28216|Betaproteobacteria,44V2Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
REGS1_k127_2036184_1	1348657.M622_00470	1.064e-103	346.0	COG3264@1|root,COG3264@2|Bacteria,1MWSA@1224|Proteobacteria,2VJTH@28216|Betaproteobacteria,2KU8B@206389|Rhodocyclales	206389|Rhodocyclales	M	mechanosensitive	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel
REGS1_k127_2075213_11	580332.Slit_1836	4.261e-92	303.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,44VKZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
REGS1_k127_2075213_0	1485544.JQKP01000017_gene643	0.0	1498.0	COG0567@1|root,COG0567@2|Bacteria,1MVBF@1224|Proteobacteria,2VJ0G@28216|Betaproteobacteria,44VD6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	2-oxoglutarate dehydrogenase N-terminus	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
REGS1_k127_2075213_5	1231391.AMZF01000025_gene1384	1.586e-156	503.0	COG0508@1|root,COG0508@2|Bacteria,1MUJD@1224|Proteobacteria,2VIEM@28216|Betaproteobacteria,3T214@506|Alcaligenaceae	28216|Betaproteobacteria	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
REGS1_k127_2075213_4	395494.Galf_2118	4.32e-163	522.0	COG0683@1|root,COG0683@2|Bacteria,1MU8V@1224|Proteobacteria,2VI6J@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Urea ABC transporter, urea binding protein	-	-	-	ko:K11959	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5
REGS1_k127_2075213_1	395494.Galf_1970	1.841e-262	857.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WC2@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,MHYT,PAS_9,dCache_2
REGS1_k127_2075213_7	580332.Slit_1833	1.074e-141	456.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,2VINX@28216|Betaproteobacteria,44WDD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase GroES domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_2075213_2	640081.Dsui_0894	8.887e-194	629.0	COG2203@1|root,COG3829@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,2KVRJ@206389|Rhodocyclales	206389|Rhodocyclales	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,Response_reg
REGS1_k127_2075213_6	648757.Rvan_1685	7.158e-152	502.0	COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2TUBY@28211|Alphaproteobacteria,3N6C2@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	EH	chorismate binding enzyme	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
REGS1_k127_2075213_10	580332.Slit_0481	2.227e-106	349.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,2VHW8@28216|Betaproteobacteria,44VDB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
REGS1_k127_2075213_8	580332.Slit_0482	1.253e-131	424.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,2VHHC@28216|Betaproteobacteria,44V22@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
REGS1_k127_2075213_12	580332.Slit_0501	3.504e-86	291.0	COG1108@1|root,COG1108@2|Bacteria,1PM37@1224|Proteobacteria,2VM6C@28216|Betaproteobacteria,44VR9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K02075	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
REGS1_k127_2075213_9	580332.Slit_0502	2.901e-130	422.0	COG0803@1|root,COG0803@2|Bacteria,1PQEX@1224|Proteobacteria,2W6SJ@28216|Betaproteobacteria,44VMA@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
REGS1_k127_2075213_3	1485544.JQKP01000010_gene846	3.751e-180	572.0	COG3746@1|root,COG3746@2|Bacteria,1MY3M@1224|Proteobacteria,2VIIP@28216|Betaproteobacteria,44VAF@713636|Nitrosomonadales	28216|Betaproteobacteria	P	phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2090021_1	580332.Slit_2262	1.655e-234	732.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,2VI3Z@28216|Betaproteobacteria,44V6H@713636|Nitrosomonadales	28216|Betaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
REGS1_k127_2090021_12	1240350.AMZE01000010_gene3834	7.883e-37	143.0	COG2050@1|root,COG2050@2|Bacteria,1QU0P@1224|Proteobacteria,1T1K4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,YiiD_C
REGS1_k127_2090021_7	1005048.CFU_2947	8.39e-106	360.0	2AEFS@1|root,314AU@2|Bacteria,1RKTV@1224|Proteobacteria,2VSSU@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2090021_5	1005048.CFU_2946	2.429e-121	396.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,2W992@28216|Betaproteobacteria,476PH@75682|Oxalobacteraceae	28216|Betaproteobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_2090021_3	1485544.JQKP01000013_gene1811	1.586e-140	449.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,2VIXG@28216|Betaproteobacteria,44V7M@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Inositol monophosphatase family	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
REGS1_k127_2090021_6	1485544.JQKP01000013_gene1810	5.513e-107	358.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,2VI2D@28216|Betaproteobacteria,44VDH@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	-	ko:K02533	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_2090021_4	580332.Slit_2257	1.619e-132	425.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VH8C@28216|Betaproteobacteria,44VK5@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
REGS1_k127_2090021_10	395494.Galf_0643	2.399e-58	206.0	COG1959@1|root,COG1959@2|Bacteria,1RDA4@1224|Proteobacteria,2VRGK@28216|Betaproteobacteria,44VWG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	iscR	-	-	ko:K13643	-	-	-	-	ko00000,ko03000	-	-	-	Rrf2
REGS1_k127_2090021_0	580332.Slit_2255	1.652e-234	732.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,44V1D@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
REGS1_k127_2090021_8	580332.Slit_2254	4.96e-69	235.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ2I@28216|Betaproteobacteria,44VSJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters	iscU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
REGS1_k127_2090021_11	580332.Slit_2253	1.592e-56	198.0	COG0316@1|root,COG0316@2|Bacteria,1RH6T@1224|Proteobacteria,2VSKY@28216|Betaproteobacteria,44VWW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM iron-sulfur cluster assembly protein IscA	iscA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
REGS1_k127_2090021_9	580332.Slit_2252	5.706e-62	219.0	COG1076@1|root,COG1076@2|Bacteria,1RHZX@1224|Proteobacteria,2VSD5@28216|Betaproteobacteria,44VVM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA	hscB	-	-	ko:K04082	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,HSCB_C
REGS1_k127_2090021_2	1485544.JQKP01000013_gene1803	4.787e-142	454.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,44VHV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
REGS1_k127_2190750_4	580332.Slit_0137	5.703e-100	334.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,2VK0Y@28216|Betaproteobacteria,44VN9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
REGS1_k127_2190750_2	1485544.JQKP01000002_gene1499	2.561e-204	640.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,2VIR9@28216|Betaproteobacteria,44VNI@713636|Nitrosomonadales	28216|Betaproteobacteria	D	TIGRFAM cell shape determining protein, MreB Mrl family	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
REGS1_k127_2190750_5	580332.Slit_0135	7.694e-37	140.0	COG0721@1|root,COG0721@2|Bacteria,1MZQP@1224|Proteobacteria,2VUFB@28216|Betaproteobacteria,44VZT@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
REGS1_k127_2190750_0	580332.Slit_0134	1.102e-289	892.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,2VIG3@28216|Betaproteobacteria,44VJ6@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
REGS1_k127_2190750_1	1485544.JQKP01000002_gene1496	2.289e-268	832.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,2VI3A@28216|Betaproteobacteria,44VKV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
REGS1_k127_2190750_3	1485544.JQKP01000002_gene1484	6.205e-188	591.0	COG0422@1|root,COG0422@2|Bacteria,1MUVV@1224|Proteobacteria,2VHS3@28216|Betaproteobacteria,44VN2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
REGS1_k127_2219153_1	580332.Slit_1422	1.463e-150	481.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,44VCI@713636|Nitrosomonadales	28216|Betaproteobacteria	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
REGS1_k127_2219153_0	580332.Slit_1421	1.263e-190	601.0	COG2262@1|root,COG2262@2|Bacteria,1MUA0@1224|Proteobacteria,2VI86@28216|Betaproteobacteria,44V2X@713636|Nitrosomonadales	28216|Betaproteobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
REGS1_k127_2219153_8	580332.Slit_1420	1.121e-37	141.0	COG1923@1|root,COG1923@2|Bacteria,1MZM1@1224|Proteobacteria,2VTXK@28216|Betaproteobacteria,44VYC@713636|Nitrosomonadales	28216|Betaproteobacteria	J	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs	hfq	-	-	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	-	-	-	ko00000,ko00001,ko03019,ko03036	-	-	-	Hfq
REGS1_k127_2219153_7	1121351.AUAP01000043_gene270	2.826e-61	213.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2VR7R@28216|Betaproteobacteria,2KQXS@206351|Neisseriales	206351|Neisseriales	E	Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
REGS1_k127_2219153_4	1485544.JQKP01000013_gene1816	2.121e-118	386.0	COG0084@1|root,COG0084@2|Bacteria,1MUC0@1224|Proteobacteria,2VHCT@28216|Betaproteobacteria,44V7Z@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TatD related DNase	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
REGS1_k127_2219153_3	580332.Slit_1536	2.013e-125	411.0	COG0470@1|root,COG0470@2|Bacteria,1MY1W@1224|Proteobacteria,2VNED@28216|Betaproteobacteria,44VBK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, delta prime subunit	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
REGS1_k127_2219153_5	580332.Slit_1535	2.196e-99	327.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,2VQ24@28216|Betaproteobacteria,44VRC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
REGS1_k127_2219153_2	580332.Slit_1534	1.883e-127	417.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,2VHD4@28216|Betaproteobacteria,44VGR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
REGS1_k127_2219153_6	580332.Slit_1532	7.325e-75	252.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,44V9T@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_2233311_8	1197906.CAJQ02000023_gene2173	1.024e-28	117.0	COG0500@1|root,COG2226@2|Bacteria,1RF23@1224|Proteobacteria,2UH95@28211|Alphaproteobacteria,3K4GS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Caenorhabditis protein of unknown function, DUF268	-	-	-	-	-	-	-	-	-	-	-	-	DUF268
REGS1_k127_2233311_4	580332.Slit_2889	6.192e-114	374.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,1RD8N@1224|Proteobacteria,2VS11@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
REGS1_k127_2233311_6	1144342.PMI40_03440	1.117e-78	272.0	COG1215@1|root,COG1215@2|Bacteria,1QVAX@1224|Proteobacteria,2WH3H@28216|Betaproteobacteria,4750G@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_2233311_2	580332.Slit_0331	2.118e-183	583.0	COG5002@1|root,COG5002@2|Bacteria,1MWF3@1224|Proteobacteria,2VIBV@28216|Betaproteobacteria,44VNZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	TIGRFAM phosphate regulon sensor kinase PhoR	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF3329,HATPase_c,HisKA,PAS,PAS_8
REGS1_k127_2233311_3	580332.Slit_0330	3.001e-117	380.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,44V17@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Two component transcriptional regulator PhoB, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_2233311_0	1485544.JQKP01000012_gene2131	1.44e-276	856.0	COG0591@1|root,COG0591@2|Bacteria,1MUBI@1224|Proteobacteria,2VHA8@28216|Betaproteobacteria,44V0T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1	-	-	SSF
REGS1_k127_2233311_5	1485544.JQKP01000012_gene2129	8.643e-113	365.0	COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,2VI7T@28216|Betaproteobacteria,44VNE@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
REGS1_k127_2233311_1	580332.Slit_2679	1.162e-269	841.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,2VHAN@28216|Betaproteobacteria,44V3U@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation	msbA	-	-	ko:K02021,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_2233311_7	582744.Msip34_0153	2.409e-46	172.0	2ARZT@1|root,31HBY@2|Bacteria,1RM6G@1224|Proteobacteria,2VT5G@28216|Betaproteobacteria,2KMUX@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_23601_13	522306.CAP2UW1_3061	1.19e-10	63.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
REGS1_k127_23601_1	1485544.JQKP01000001_gene1232	1.884e-149	482.0	COG2308@1|root,COG2308@2|Bacteria,1P9A0@1224|Proteobacteria,2VISX@28216|Betaproteobacteria,44V9V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_23601_6	1163617.SCD_n01375	9.7e-45	166.0	2DBSM@1|root,32TY0@2|Bacteria,1N5UN@1224|Proteobacteria,2VV1Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
REGS1_k127_23601_8	580332.Slit_1229	7.348e-40	156.0	COG3063@1|root,COG3063@2|Bacteria	2|Bacteria	NU	photosynthesis	-	-	2.7.11.1	ko:K12132,ko:K20543	-	-	-	-	ko00000,ko01000,ko01001,ko02000	1.B.55.3	-	-	AAA_16,NfrA_C,Pkinase,TPR_10,TPR_12,TPR_14,TPR_16,TPR_19,TPR_8
REGS1_k127_23601_0	580332.Slit_1228	0.0	1223.0	COG0744@1|root,COG0744@2|Bacteria,1QTST@1224|Proteobacteria	1224|Proteobacteria	M	Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits)	mrcB	-	2.4.1.129,3.4.16.4	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase,UB2H
REGS1_k127_23601_9	580332.Slit_1242	2.159e-38	146.0	COG0664@1|root,COG0664@2|Bacteria,1N6WV@1224|Proteobacteria,2VWSV@28216|Betaproteobacteria,44WIM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_23601_5	580332.Slit_2862	1.492e-63	222.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,2VQ18@28216|Betaproteobacteria,44W9Q@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	Redoxin
REGS1_k127_23601_2	580332.Slit_1250	4.181e-127	409.0	COG1187@1|root,COG1187@2|Bacteria,1MU6M@1224|Proteobacteria,2VIXH@28216|Betaproteobacteria,44VH4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_23601_7	557599.MKAN_28795	1.008e-40	160.0	28MQW@1|root,32WFA@2|Bacteria,2I50D@201174|Actinobacteria,23F8X@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_23601_12	1504672.669783209	3.832e-18	87.0	2E80T@1|root,332F0@2|Bacteria,1N7RY@1224|Proteobacteria,2VX4M@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
REGS1_k127_23601_3	102129.Lepto7375DRAFT_7604	6.758e-95	317.0	COG4912@1|root,COG4912@2|Bacteria,1G63N@1117|Cyanobacteria,1HFFN@1150|Oscillatoriales	1117|Cyanobacteria	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
REGS1_k127_23601_4	261292.Nit79A3_2486	1.194e-72	248.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2VSPX@28216|Betaproteobacteria,37475@32003|Nitrosomonadales	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
REGS1_k127_2363648_3	580332.Slit_2635	3.44e-20	92.0	2EHK0@1|root,33BBV@2|Bacteria,1NGIK@1224|Proteobacteria,2VXN8@28216|Betaproteobacteria,44W3C@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_2363648_0	580332.Slit_2634	5.554e-175	566.0	COG0642@1|root,COG2205@2|Bacteria,1MXF8@1224|Proteobacteria,2WHEY@28216|Betaproteobacteria,44V0X@713636|Nitrosomonadales	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS_8
REGS1_k127_2363648_1	1198452.Jab_2c29030	2.833e-146	479.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,472RM@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Sigma-54 interaction domain	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_2363648_2	1485544.JQKP01000001_gene1021	3.196e-79	272.0	COG3023@1|root,COG3023@2|Bacteria,1RDHU@1224|Proteobacteria,2VR5A@28216|Betaproteobacteria,44VTD@713636|Nitrosomonadales	28216|Betaproteobacteria	V	N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD	ampD	GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Amidase_2
REGS1_k127_2431147_0	580332.Slit_2617	0.0	1726.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VI3F@28216|Betaproteobacteria,44VJ0@713636|Nitrosomonadales	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_2431147_1	1485544.JQKP01000012_gene2143	9.759e-139	449.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VJAC@28216|Betaproteobacteria,44VMF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_D23
REGS1_k127_2431147_3	633131.TR2A62_0064	4.6e-19	93.0	COG0790@1|root,COG0790@2|Bacteria,1N6ZB@1224|Proteobacteria,2UJ1A@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Sel1-like repeats.	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
REGS1_k127_2431147_2	246197.MXAN_6138	2.256e-113	367.0	COG0262@1|root,COG0262@2|Bacteria,1QH1Q@1224|Proteobacteria,4341U@68525|delta/epsilon subdivisions,2X4QE@28221|Deltaproteobacteria,2YZE6@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_2441309_0	580332.Slit_2180	1.339e-129	420.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2VH2B@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
REGS1_k127_2441309_1	118161.KB235922_gene3501	1.774e-50	188.0	COG5595@1|root,COG5595@2|Bacteria	2|Bacteria	S	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)	HD1486	-	-	-	-	-	-	-	-	-	-	-	DUF2310
REGS1_k127_2441309_2	1232410.KI421412_gene26	3.714e-38	148.0	COG5637@1|root,COG5637@2|Bacteria,1MZY2@1224|Proteobacteria,430UG@68525|delta/epsilon subdivisions,2WVX4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2448131_0	580332.Slit_1755	2.793e-119	387.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,2VJ71@28216|Betaproteobacteria,44VBJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	FtsJ-like methyltransferase	rlmM	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
REGS1_k127_2448131_2	396588.Tgr7_0009	6.441e-47	180.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,1S27K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA,MipZ
REGS1_k127_2448131_1	580332.Slit_0323	3.401e-100	338.0	2DBUQ@1|root,2ZB76@2|Bacteria,1R4DM@1224|Proteobacteria,2VP87@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2495563_12	765911.Thivi_3499	6.399e-41	151.0	COG1196@1|root,COG1196@2|Bacteria,1P2I9@1224|Proteobacteria	1224|Proteobacteria	D	Domain of unknown function (DUF4297)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4297
REGS1_k127_2495563_7	765911.Thivi_3498	1.334e-95	315.0	2CMZ5@1|root,32SFV@2|Bacteria,1N2UE@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2495563_0	765911.Thivi_3497	1.787e-305	947.0	COG1196@1|root,COG1196@2|Bacteria,1R1SX@1224|Proteobacteria,1SH85@1236|Gammaproteobacteria,1X070@135613|Chromatiales	135613|Chromatiales	D	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
REGS1_k127_2495563_2	580332.Slit_2313	6.49e-183	576.0	COG0320@1|root,COG0320@2|Bacteria,1MVRD@1224|Proteobacteria,2VIFE@28216|Betaproteobacteria,44VKS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
REGS1_k127_2495563_8	580332.Slit_0723	9.139e-93	312.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,2VQ1Y@28216|Betaproteobacteria,44V7A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
REGS1_k127_2495563_14	580332.Slit_0724	3.7e-33	129.0	COG2921@1|root,COG2921@2|Bacteria,1RGV5@1224|Proteobacteria,2VTY5@28216|Betaproteobacteria,44W1W@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF493)	ybeD	-	-	ko:K09158	-	-	-	-	ko00000	-	-	-	DUF493
REGS1_k127_2495563_5	580332.Slit_0725	8.135e-146	466.0	COG0115@1|root,COG0115@2|Bacteria,1MVAT@1224|Proteobacteria,2VIVK@28216|Betaproteobacteria,44WCS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM aminotransferase class IV	dat	-	2.6.1.21	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	-	R01148,R01582,R02459,R02851,R02924,R05053	RC00006,RC00008,RC00025	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4
REGS1_k127_2495563_6	395494.Galf_2079	1.331e-122	404.0	COG1686@1|root,COG1686@2|Bacteria,1MUU7@1224|Proteobacteria,2VH46@28216|Betaproteobacteria,44WE9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1	dacC	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
REGS1_k127_2495563_3	580332.Slit_0958	5.619e-156	499.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,2VHJF@28216|Betaproteobacteria,44V4D@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
REGS1_k127_2495563_13	1163617.SCD_n02212	6.321e-35	137.0	COG1585@1|root,COG1585@2|Bacteria,1N474@1224|Proteobacteria,2VWDX@28216|Betaproteobacteria	28216|Betaproteobacteria	OU	Membrane protein implicated in regulation of membrane protease activity	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
REGS1_k127_2495563_4	1163617.SCD_n02211	1.832e-150	480.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHBD@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM Band 7 protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7,Band_7_C
REGS1_k127_2495563_10	1266925.JHVX01000002_gene996	1.095e-75	256.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2VSPX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
REGS1_k127_2495563_1	580332.Slit_0959	1.429e-218	680.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2VIRX@28216|Betaproteobacteria,44VPG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
REGS1_k127_2495563_15	580332.Slit_0960	2.587e-30	123.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2VU6T@28216|Betaproteobacteria,44VZC@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
REGS1_k127_2495563_9	580332.Slit_0961	7.408e-91	303.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,44VEI@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
REGS1_k127_2495563_11	580332.Slit_0961	1.012e-69	239.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,44VEI@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
REGS1_k127_2603903_0	580332.Slit_2103	0.0	1515.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,2VH6Z@28216|Betaproteobacteria,44VM0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
REGS1_k127_2603903_6	580332.Slit_0490	7.607e-33	135.0	COG3149@1|root,COG3149@2|Bacteria,1NAXX@1224|Proteobacteria,2VY4T@28216|Betaproteobacteria	28216|Betaproteobacteria	U	General secretion pathway	gspM	-	-	ko:K02462	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSM
REGS1_k127_2603903_2	580332.Slit_0491	2.866e-75	267.0	COG3297@1|root,COG3297@2|Bacteria	2|Bacteria	U	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,T2SSL
REGS1_k127_2603903_1	580332.Slit_0492	8.535e-88	304.0	COG3156@1|root,COG3156@2|Bacteria,1RBNV@1224|Proteobacteria,2VS9P@28216|Betaproteobacteria	28216|Betaproteobacteria	U	general secretion pathway protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
REGS1_k127_2603903_4	580332.Slit_0493	1.398e-44	168.0	COG4795@1|root,COG4795@2|Bacteria	2|Bacteria	U	General secretion pathway protein	gspJ	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
REGS1_k127_2603903_5	580332.Slit_0494	2.369e-41	156.0	COG2165@1|root,COG2165@2|Bacteria,1N737@1224|Proteobacteria	1224|Proteobacteria	NU	General secretion pathway protein I	gspI	GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSI
REGS1_k127_2603903_9	402626.Rpic_3392	1.731e-11	72.0	COG2165@1|root,COG2165@2|Bacteria,1N8AD@1224|Proteobacteria,2VWBA@28216|Betaproteobacteria,1K7EA@119060|Burkholderiaceae	28216|Betaproteobacteria	U	general secretion pathway protein	gspH	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspH,N_methyl
REGS1_k127_2603903_3	264198.Reut_A3221	3.944e-59	208.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR7N@28216|Betaproteobacteria,1KH6M@119060|Burkholderiaceae	28216|Betaproteobacteria	U	general secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_2607548_2	640081.Dsui_1384	7.975e-64	227.0	COG2165@1|root,COG2165@2|Bacteria,1REMT@1224|Proteobacteria,2VR8U@28216|Betaproteobacteria,2KWCN@206389|Rhodocyclales	206389|Rhodocyclales	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
REGS1_k127_2607548_0	580332.Slit_0444	6.867e-293	906.0	COG0642@1|root,COG2205@2|Bacteria	580332.Slit_0444|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2607548_1	580332.Slit_0445	8.068e-211	660.0	COG1643@1|root,COG2852@1|root,COG1643@2|Bacteria,COG2852@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,44VDV@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
REGS1_k127_2665915_3	580332.Slit_0751	7.207e-63	219.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,44V6U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
REGS1_k127_2665915_1	1485544.JQKP01000004_gene455	7.196e-79	265.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,2VQ5I@28216|Betaproteobacteria,44VPJ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
REGS1_k127_2665915_2	580332.Slit_0749	3.961e-76	267.0	2DG57@1|root,2ZUJK@2|Bacteria,1QZYA@1224|Proteobacteria,2WHPQ@28216|Betaproteobacteria,44VQW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM PEGA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
REGS1_k127_2665915_0	1485544.JQKP01000003_gene125	1.258e-95	314.0	COG0494@1|root,COG0494@2|Bacteria,1RDGJ@1224|Proteobacteria,2VIDX@28216|Betaproteobacteria,44VS0@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
REGS1_k127_2665915_4	580332.Slit_0753	5.432e-19	86.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,2VH5D@28216|Betaproteobacteria,44V0D@713636|Nitrosomonadales	28216|Betaproteobacteria	J	elongation factor Tu	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
REGS1_k127_2713499_6	580332.Slit_0983	4.928e-65	228.0	COG1686@1|root,COG1686@2|Bacteria,1MWZA@1224|Proteobacteria,2VH1S@28216|Betaproteobacteria,44V9A@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1	pbpG	-	-	ko:K07262	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
REGS1_k127_2713499_2	395494.Galf_2455	1.503e-277	867.0	COG5265@1|root,COG5265@2|Bacteria,1NSKS@1224|Proteobacteria,2WGG3@28216|Betaproteobacteria,44VCR@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter transmembrane region	atm1	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_2713499_9	1434929.X946_5190	1.846e-32	135.0	2A84T@1|root,30X5J@2|Bacteria,1PIZC@1224|Proteobacteria,2W7JC@28216|Betaproteobacteria,1KEPZ@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2713499_1	697282.Mettu_2355	0.0	1079.0	28HYC@1|root,2Z83T@2|Bacteria,1QEBM@1224|Proteobacteria,1RRCK@1236|Gammaproteobacteria,1XDJX@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2713499_4	1485544.JQKP01000020_gene62	1.179e-130	432.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,2VI41@28216|Betaproteobacteria,44V32@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	clsB	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
REGS1_k127_2713499_5	580332.Slit_0978	2.023e-95	318.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VJYW@28216|Betaproteobacteria,44VCG@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
REGS1_k127_2713499_10	1499967.BAYZ01000116_gene3146	1.173e-24	107.0	2EEHS@1|root,338BM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2713499_0	265072.Mfla_0508	0.0	1160.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,2VH1K@28216|Betaproteobacteria,2KKYH@206350|Nitrosomonadales	206350|Nitrosomonadales	O	TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA	-	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_2713499_7	580332.Slit_0966	9.973e-40	150.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,2VSCU@28216|Betaproteobacteria,44VZ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
REGS1_k127_2713499_8	580332.Slit_0967	3.001e-36	139.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,44VZU@713636|Nitrosomonadales	28216|Betaproteobacteria	K	SMART Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_2713499_3	857087.Metme_3221	8.16e-153	508.0	COG4249@1|root,COG4249@2|Bacteria,1QU7W@1224|Proteobacteria,1RZ8P@1236|Gammaproteobacteria,1XG8B@135618|Methylococcales	135618|Methylococcales	S	Peptidase C13 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C13
REGS1_k127_2739194_3	580332.Slit_2056	2.36e-88	295.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,2VJRD@28216|Betaproteobacteria,44VEZ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
REGS1_k127_2739194_2	1485544.JQKP01000011_gene759	1.27e-172	549.0	COG2956@1|root,COG2956@2|Bacteria,1MVDP@1224|Proteobacteria,2VH49@28216|Betaproteobacteria,44UYA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane	lapB	-	-	ko:K19804	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_7
REGS1_k127_2739194_4	580332.Slit_2059	1.587e-47	171.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,2VSPN@28216|Betaproteobacteria,44VZM@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himD	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_2739194_0	580332.Slit_2060	0.0	1022.0	COG0539@1|root,COG1093@1|root,COG0539@2|Bacteria,COG1093@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,44V1X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
REGS1_k127_2739194_1	580332.Slit_2061	1.946e-193	609.0	COG0128@1|root,COG0283@1|root,COG0128@2|Bacteria,COG0283@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,44VC3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
REGS1_k127_274223_9	580332.Slit_0968	2.838e-96	318.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,44VC6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	icd_2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
REGS1_k127_274223_10	580332.Slit_0969	2.277e-93	308.0	COG1187@1|root,COG1187@2|Bacteria,1R9VV@1224|Proteobacteria,2VQAQ@28216|Betaproteobacteria,44UYV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluE	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
REGS1_k127_274223_17	62928.azo3237	4.899e-28	114.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,2VTX5@28216|Betaproteobacteria,2KXAG@206389|Rhodocyclales	206389|Rhodocyclales	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
REGS1_k127_274223_8	580332.Slit_0972	2.619e-97	322.0	COG2928@1|root,COG2928@2|Bacteria,1MWT5@1224|Proteobacteria,2VH65@28216|Betaproteobacteria,44VQ6@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
REGS1_k127_274223_2	1485544.JQKP01000005_gene411	0.0	1107.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,2VHKQ@28216|Betaproteobacteria,44V9U@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
REGS1_k127_274223_14	580332.Slit_0974	1.058e-44	165.0	COG4290@1|root,COG4290@2|Bacteria,1MZEZ@1224|Proteobacteria,2VTZ7@28216|Betaproteobacteria,44W1Y@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM guanine-specific ribonuclease N1 and T1	rnaSA	-	3.1.27.3	ko:K01167	-	-	-	-	ko00000,ko01000,ko03016,ko03019	-	-	-	Ribonuclease
REGS1_k127_274223_15	580332.Slit_0975	4.279e-42	158.0	COG2732@1|root,COG2732@2|Bacteria,1PCTM@1224|Proteobacteria,2WA4A@28216|Betaproteobacteria,44WMH@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Barstar (barnase inhibitor)	-	-	-	-	-	-	-	-	-	-	-	-	Barstar
REGS1_k127_274223_13	395494.Galf_2461	4.211e-64	222.0	COG0494@1|root,COG0494@2|Bacteria,1RH6N@1224|Proteobacteria,2VR3U@28216|Betaproteobacteria,44VVC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	NUDIX domain	ntpA	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
REGS1_k127_274223_4	580332.Slit_0977	1.124e-197	621.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,2VH6N@28216|Betaproteobacteria,44VD1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
REGS1_k127_274223_3	228410.NE1326	2.578e-226	712.0	COG0312@1|root,COG0312@2|Bacteria,1MUSK@1224|Proteobacteria,2VHJ9@28216|Betaproteobacteria,372FQ@32003|Nitrosomonadales	28216|Betaproteobacteria	S	modulator of DNA gyrase	tldD	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
REGS1_k127_274223_6	580332.Slit_2094	6.006e-148	471.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,2VIR4@28216|Betaproteobacteria,44VJE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	opaA	-	3.5.5.1	ko:K01501,ko:K11206	ko00380,ko00460,ko00627,ko00643,ko00910,ko01120,map00380,map00460,map00627,map00643,map00910,map01120	-	R00540,R01887,R03093,R03542,R05591,R07855	RC00315,RC00325,RC00617,RC00959,RC02811	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
REGS1_k127_274223_1	580332.Slit_2095	0.0	1110.0	COG3164@1|root,COG3164@2|Bacteria,1MXWF@1224|Proteobacteria,2VH52@28216|Betaproteobacteria,44VDF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2,DUF3971
REGS1_k127_274223_0	580332.Slit_2096	0.0	1195.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,2VH5B@28216|Betaproteobacteria,44V1N@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
REGS1_k127_274223_12	580332.Slit_1174	4.675e-66	229.0	COG0526@1|root,COG0526@2|Bacteria,1RKKW@1224|Proteobacteria,2WEVJ@28216|Betaproteobacteria	28216|Betaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_274223_5	580332.Slit_0328	1.388e-149	481.0	COG3391@1|root,COG3391@2|Bacteria,1NZ87@1224|Proteobacteria	1224|Proteobacteria	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_274223_7	580332.Slit_0327	1.122e-123	402.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,44VI2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_274223_11	395494.Galf_1120	8.848e-80	277.0	COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2VINR@28216|Betaproteobacteria,44VQ0@713636|Nitrosomonadales	28216|Betaproteobacteria	DM	Lysin motif	-	-	-	ko:K06194	-	-	-	-	ko00000	1.A.34.1.2	-	-	LysM,Peptidase_M23
REGS1_k127_274223_16	1485544.JQKP01000001_gene1085	2.506e-33	129.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2VQ3B@28216|Betaproteobacteria,44VA5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_2879006_8	580332.Slit_1364	1.237e-15	77.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,44UYT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
REGS1_k127_2879006_6	1485544.JQKP01000001_gene1258	1.375e-26	109.0	COG2835@1|root,COG2835@2|Bacteria,1N6Y2@1224|Proteobacteria,2VW58@28216|Betaproteobacteria,44W2Q@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Trm112p-like protein	ycaR	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
REGS1_k127_2879006_0	1485544.JQKP01000001_gene1257	8.823e-139	445.0	COG1212@1|root,COG1212@2|Bacteria,1MUUU@1224|Proteobacteria,2VINM@28216|Betaproteobacteria,44VH9@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
REGS1_k127_2879006_1	1485544.JQKP01000001_gene1256	2.569e-116	377.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,2VH1C@28216|Betaproteobacteria,44VKH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
REGS1_k127_2879006_2	580332.Slit_1360	7.555e-57	203.0	COG3193@1|root,COG3193@2|Bacteria,1RGUD@1224|Proteobacteria,2VRBU@28216|Betaproteobacteria,44VTZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
REGS1_k127_2879006_3	1144319.PMI16_03438	1.505e-55	198.0	2ADX9@1|root,313PE@2|Bacteria,1RGY0@1224|Proteobacteria,2VUGJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2846
REGS1_k127_2879006_4	1385515.N791_03355	2.68e-31	129.0	2ADZZ@1|root,313SI@2|Bacteria,1QD4R@1224|Proteobacteria,1T94P@1236|Gammaproteobacteria,1XBNY@135614|Xanthomonadales	135614|Xanthomonadales	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
REGS1_k127_2879006_5	580332.Slit_0796	1.302e-28	119.0	2ED0C@1|root,336XB@2|Bacteria,1ND2K@1224|Proteobacteria,2VXBS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_2879006_7	580332.Slit_2777	1.044e-17	85.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria	28216|Betaproteobacteria	O	serine protease	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
REGS1_k127_3007883_12	580332.Slit_2740	1.647e-26	112.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,44V5D@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome C assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_3007883_0	1485544.JQKP01000001_gene1297	2.294e-240	749.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,2VJ3W@28216|Betaproteobacteria,44VCY@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
REGS1_k127_3007883_5	395494.Galf_2702	8.582e-120	387.0	COG0637@1|root,COG0637@2|Bacteria,1PUMZ@1224|Proteobacteria,2VHJ3@28216|Betaproteobacteria,44VFS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3	cbbY	-	-	-	-	-	-	-	-	-	-	-	HAD_2
REGS1_k127_3007883_16	640511.BC1002_6565	1.093e-16	88.0	2DXFP@1|root,344TH@2|Bacteria,1PZNS@1224|Proteobacteria,2W444@28216|Betaproteobacteria,1KEMY@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4376)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4376
REGS1_k127_3007883_21	706191.PANA_3139	8.996e-10	67.0	COG2110@1|root,COG2110@2|Bacteria,1RDMN@1224|Proteobacteria,1S6U8@1236|Gammaproteobacteria,3W0PC@53335|Pantoea	1236|Gammaproteobacteria	S	Caudovirales tail fibre assembly protein, lambda gpK	tfaE	-	-	-	-	-	-	-	-	-	-	-	Caudo_TAP
REGS1_k127_3007883_14	556269.ACDQ01000006_gene1643	3.502e-21	109.0	COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria	1224|Proteobacteria	S	phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
REGS1_k127_3007883_2	580332.Slit_1896	2.341e-130	440.0	29XU2@1|root,30JK6@2|Bacteria,1PGBR@1224|Proteobacteria,2W89Q@28216|Betaproteobacteria,44WNH@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_17	1221522.B723_06235	1.461e-13	84.0	COG5301@1|root,COG5301@2|Bacteria,1MWNN@1224|Proteobacteria,1S2BE@1236|Gammaproteobacteria,1YQ51@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Phage tail-collar fibre protein	-	-	-	-	-	-	-	-	-	-	-	-	Collar,DUF3751
REGS1_k127_3007883_6	580332.Slit_1896	4.247e-118	400.0	29XU2@1|root,30JK6@2|Bacteria,1PGBR@1224|Proteobacteria,2W89Q@28216|Betaproteobacteria,44WNH@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_7	279714.FuraDRAFT_0294	9.767e-57	224.0	COG4675@1|root,COG4675@2|Bacteria,1N2XN@1224|Proteobacteria	1224|Proteobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_22	556269.ACDQ01000006_gene1643	3.087e-09	70.0	COG4675@1|root,COG4675@2|Bacteria,1N0FZ@1224|Proteobacteria	1224|Proteobacteria	S	phage Tail Collar	-	-	-	-	-	-	-	-	-	-	-	-	Collar
REGS1_k127_3007883_4	580332.Slit_1896	3.323e-128	438.0	29XU2@1|root,30JK6@2|Bacteria,1PGBR@1224|Proteobacteria,2W89Q@28216|Betaproteobacteria,44WNH@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_18	1121441.AUCX01000014_gene507	2.593e-13	83.0	COG5563@1|root,COG5563@2|Bacteria,1Q0JE@1224|Proteobacteria,430IH@68525|delta/epsilon subdivisions,2X0GF@28221|Deltaproteobacteria,2MD65@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_20	1207076.ALAT01000150_gene255	6.686e-11	76.0	COG3979@1|root,COG3979@2|Bacteria,1RGTZ@1224|Proteobacteria,1SPPU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_10	580332.Slit_1897	6.81e-43	179.0	28XAN@1|root,2ZJ8N@2|Bacteria,1RAE9@1224|Proteobacteria,2VSKB@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_1	580332.Slit_1898	1.828e-162	518.0	COG3299@1|root,COG3299@2|Bacteria,1MXKB@1224|Proteobacteria,2VNZ9@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Baseplate J-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J
REGS1_k127_3007883_11	580332.Slit_1899	5.578e-37	144.0	2C2XJ@1|root,32W94@2|Bacteria,1N20H@1224|Proteobacteria,2VUQ5@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_9	580332.Slit_1900	1.128e-50	188.0	COG3501@1|root,COG3501@2|Bacteria,1N2WW@1224|Proteobacteria,2VVJZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Baseplate assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_3	580332.Slit_1901	6.109e-129	422.0	COG3500@1|root,COG3500@2|Bacteria,1R6WJ@1224|Proteobacteria,2VNXA@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Late control gene D protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_8	580332.Slit_1902	4.012e-52	197.0	COG1652@1|root,COG1652@2|Bacteria,1REA6@1224|Proteobacteria,2VRX2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_15	1286093.C266_14134	3.211e-17	95.0	COG4942@1|root,COG4942@2|Bacteria,1QTW5@1224|Proteobacteria,2WGFW@28216|Betaproteobacteria,1K552@119060|Burkholderiaceae	28216|Betaproteobacteria	D	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_19	580332.Slit_1904	2.089e-11	68.0	COG5005@1|root,COG5005@2|Bacteria,1MZXA@1224|Proteobacteria,2VVK2@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phage virion morphogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3007883_13	1070319.CAGGBEG34_330029	1.171e-24	108.0	2C2XK@1|root,32ZQV@2|Bacteria,1N85V@1224|Proteobacteria,2VW0J@28216|Betaproteobacteria,1KAIF@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3132371_5	153948.NAL212_2768	2.243e-81	276.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria,372KA@32003|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
REGS1_k127_3132371_2	265072.Mfla_1368	5.021e-218	682.0	COG0448@1|root,COG0448@2|Bacteria,1MVTC@1224|Proteobacteria,2VIP2@28216|Betaproteobacteria,2KMA7@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
REGS1_k127_3132371_0	265072.Mfla_1367	0.0	1095.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,2VGZZ@28216|Betaproteobacteria,2KP8I@206350|Nitrosomonadales	206350|Nitrosomonadales	F	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
REGS1_k127_3132371_1	1519464.HY22_05665	4.813e-253	794.0	COG0166@1|root,COG0166@2|Bacteria,1FDEJ@1090|Chlorobi	1090|Chlorobi	F	Belongs to the GPI family	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
REGS1_k127_3132371_4	265072.Mfla_1472	3.853e-164	531.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,2VH1G@28216|Betaproteobacteria,2KM1X@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
REGS1_k127_3132371_7	377629.TERTU_1731	1.028e-15	89.0	COG4508@1|root,COG4508@2|Bacteria,1RAX1@1224|Proteobacteria,1RYFG@1236|Gammaproteobacteria,2PNB5@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	dUTPase	dut	-	-	-	-	-	-	-	-	-	-	-	dUTPase_2
REGS1_k127_3132371_3	323848.Nmul_A0912	5.004e-168	543.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,1MU9M@1224|Proteobacteria,2VJUR@28216|Betaproteobacteria,372Y5@32003|Nitrosomonadales	28216|Betaproteobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
REGS1_k127_3132371_6	555778.Hneap_0011	6.673e-35	136.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SAT7@1236|Gammaproteobacteria,1WZ6X@135613|Chromatiales	135613|Chromatiales	V	Protein of unknown function (DUF559)	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
REGS1_k127_3174738_29	384765.SIAM614_08304	4.524e-16	85.0	COG0582@1|root,COG0582@2|Bacteria,1RAN4@1224|Proteobacteria,2U47D@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
REGS1_k127_3174738_20	1485544.JQKP01000002_gene1370	1.019e-74	267.0	COG0507@1|root,COG0507@2|Bacteria	2|Bacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	traA	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
REGS1_k127_3174738_23	459495.SPLC1_S271130	2.15e-64	224.0	COG1396@1|root,COG1396@2|Bacteria,1G0BK@1117|Cyanobacteria,1HFS5@1150|Oscillatoriales	1117|Cyanobacteria	K	Restriction endonuclease PvuII	-	-	-	-	-	-	-	-	-	-	-	-	Endonuc-PvuII,HTH_3
REGS1_k127_3174738_27	1114922.CIFAM_10_01055	3.664e-19	89.0	COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,1SGD3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Helix-turn-helix domain	ahdIC	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_3174738_10	306281.AJLK01000063_gene5150	4.134e-151	484.0	COG0863@1|root,COG0863@2|Bacteria,1G2AV@1117|Cyanobacteria,1JHDW@1189|Stigonemataceae	1117|Cyanobacteria	L	DNA methylase	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
REGS1_k127_3174738_6	1485544.JQKP01000001_gene976	1.271e-213	680.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,2VJCZ@28216|Betaproteobacteria,44V8Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	SurA N-terminal domain	ppiD	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_3174738_11	580332.Slit_1799	2.234e-143	458.0	COG0623@1|root,COG0623@2|Bacteria,1MV05@1224|Proteobacteria,2VIHE@28216|Betaproteobacteria,44VGX@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Enoyl-(Acyl carrier protein) reductase	fabI	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_3174738_18	1485544.JQKP01000007_gene1994	1.619e-93	310.0	COG4133@1|root,COG4133@2|Bacteria,1MZPC@1224|Proteobacteria,2VMGA@28216|Betaproteobacteria,44V0F@713636|Nitrosomonadales	28216|Betaproteobacteria	P	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
REGS1_k127_3174738_17	395494.Galf_1772	6.196e-99	328.0	COG2386@1|root,COG2386@2|Bacteria,1NJB0@1224|Proteobacteria,2VNPU@28216|Betaproteobacteria,44VAM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
REGS1_k127_3174738_15	395494.Galf_1771	5.575e-122	394.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,2VHF8@28216|Betaproteobacteria,44VN4@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
REGS1_k127_3174738_30	580332.Slit_1795	3.174e-13	70.0	COG3114@1|root,COG3114@2|Bacteria	2|Bacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmD	GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678	-	ko:K02196	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.107	-	iB21_1397.B21_02084,iBWG_1329.BWG_1971,iE2348C_1286.E2348C_2342,iEC042_1314.EC042_2439,iEC55989_1330.EC55989_2451,iECABU_c1320.ECABU_c25320,iECBD_1354.ECBD_1462,iECB_1328.ECB_02125,iECDH10B_1368.ECDH10B_2355,iECDH1ME8569_1439.ECDH1ME8569_2133,iECD_1391.ECD_02125,iECED1_1282.ECED1_2663,iECH74115_1262.ECH74115_3335,iECIAI1_1343.ECIAI1_2280,iECIAI39_1322.ECIAI39_2336,iECNA114_1301.ECNA114_2290,iECO103_1326.ECO103_2673,iECO111_1330.ECO111_2934,iECO26_1355.ECO26_3124,iECOK1_1307.ECOK1_2432,iECP_1309.ECP_2238,iECS88_1305.ECS88_2345,iECSE_1348.ECSE_2466,iECSF_1327.ECSF_2079,iECSP_1301.ECSP_3077,iECUMN_1333.ECUMN_2533,iECs_1301.ECs3087,iEKO11_1354.EKO11_1558,iETEC_1333.ETEC_2332,iEcDH1_1363.EcDH1_1461,iEcE24377_1341.EcE24377A_2497,iEcHS_1320.EcHS_A2336,iEcSMS35_1347.EcSMS35_2346,iEcolC_1368.EcolC_1452,iJO1366.b2198,iLF82_1304.LF82_0276,iNRG857_1313.NRG857_11155,iSDY_1059.SDY_0880,iSFV_1184.SFV_2274,iSF_1195.SF2282,iSSON_1240.SSON_2256,iS_1188.S2412,iUMN146_1321.UM146_05815,iUMNK88_1353.UMNK88_2745,iUTI89_1310.UTI89_C2476,iY75_1357.Y75_RS11500,iZ_1308.Z3455,ic_1306.c2735	CcmD
REGS1_k127_3174738_25	395494.Galf_1769	2.669e-42	160.0	COG2332@1|root,COG2332@2|Bacteria,1RHN5@1224|Proteobacteria,2VRKZ@28216|Betaproteobacteria,44VV9@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
REGS1_k127_3174738_3	1485544.JQKP01000007_gene1989	0.0	1016.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,2VHUE@28216|Betaproteobacteria,44VEM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
REGS1_k127_3174738_21	580332.Slit_1792	6.649e-73	250.0	COG0526@1|root,COG0526@2|Bacteria,1RI3N@1224|Proteobacteria,2VR8D@28216|Betaproteobacteria,44VSS@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA,Redoxin
REGS1_k127_3174738_24	580332.Slit_1791	1.806e-55	198.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,2VU7C@28216|Betaproteobacteria,44VXQ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Cytochrome C biogenesis protein	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
REGS1_k127_3174738_9	1485544.JQKP01000007_gene1986	1.253e-158	510.0	COG4235@1|root,COG4235@2|Bacteria,1MY4J@1224|Proteobacteria,2VQ05@28216|Betaproteobacteria,44V8W@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM cytochrome c-type biogenesis protein CcmI	cycH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	TPR_16,TPR_2
REGS1_k127_3174738_13	395494.Galf_0636	2.282e-127	450.0	COG2114@1|root,COG2982@1|root,COG3064@1|root,COG2114@2|Bacteria,COG2982@2|Bacteria,COG3064@2|Bacteria,1QZY2@1224|Proteobacteria,2VTEI@28216|Betaproteobacteria,44WBC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3174738_4	580332.Slit_1787	4.187e-234	728.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,2VI01@28216|Betaproteobacteria,44VPA@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class I and II	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_3174738_0	1485544.JQKP01000002_gene1421	0.0	1517.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VKKR@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
REGS1_k127_3174738_12	1485544.JQKP01000002_gene1420	6.642e-129	422.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2VI8Z@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
REGS1_k127_3174738_8	1485544.JQKP01000002_gene1419	5.985e-185	595.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VHFP@28216|Betaproteobacteria,44WDN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_3174738_1	580332.Slit_2782	0.0	1274.0	COG0188@1|root,COG0188@2|Bacteria,1MURI@1224|Proteobacteria,2VH7P@28216|Betaproteobacteria,44V8A@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parC	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
REGS1_k127_3174738_2	580332.Slit_2781	0.0	1174.0	COG0187@1|root,COG0187@2|Bacteria,1MVH1@1224|Proteobacteria,2VHBQ@28216|Betaproteobacteria,44V5N@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule	parE	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
REGS1_k127_3174738_14	1122963.AUHB01000006_gene2334	4.256e-127	414.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,2TRUP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	virion core protein (lumpy skin disease virus)	ydjI	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
REGS1_k127_3174738_22	1282362.AEAC466_17560	1.227e-64	228.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
REGS1_k127_3174738_19	1282362.AEAC466_17555	7.359e-81	287.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,2U2BP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
REGS1_k127_3174738_28	1282362.AEAC466_17545	7.103e-18	85.0	2EGTE@1|root,33AJI@2|Bacteria,1NM7R@1224|Proteobacteria,2UMW0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
REGS1_k127_3174738_5	1282362.AEAC466_17540	1.283e-221	701.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,2TWWC@28211|Alphaproteobacteria,2KJIB@204458|Caulobacterales	204458|Caulobacterales	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
REGS1_k127_3174738_7	1121022.ABENE_17250	1.853e-187	602.0	COG1231@1|root,COG1231@2|Bacteria,1QWEG@1224|Proteobacteria,2U4R0@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
REGS1_k127_3174738_16	1282362.AEAC466_17530	1.337e-117	389.0	28M67@1|root,2ZAJW@2|Bacteria,1NV1K@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3174738_26	1121022.ABENE_17240	4.415e-39	148.0	COG1586@1|root,COG1586@2|Bacteria,1RH88@1224|Proteobacteria,2U5D3@28211|Alphaproteobacteria,2KJB6@204458|Caulobacterales	204458|Caulobacterales	E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine	-	-	-	-	-	-	-	-	-	-	-	-	AdoMet_dc
REGS1_k127_3174738_32	45351.EDO42616	0.0001808	48.0	COG0666@1|root,KOG3528@1|root,KOG0504@2759|Eukaryota,KOG3528@2759|Eukaryota,38D44@33154|Opisthokonta,3BAUX@33208|Metazoa	33208|Metazoa	T	GKAP/Homer scaffold activity	-	-	-	ko:K15009	ko04724,map04724	-	-	-	ko00000,ko00001	-	-	-	Ank_2,Ank_4,FERM_f0,PDZ,SAM_1,SH3_2
REGS1_k127_3196425_1	580332.Slit_2851	2.458e-218	689.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,44VF5@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
REGS1_k127_3196425_4	1485544.JQKP01000002_gene1514	5.325e-65	226.0	COG0757@1|root,COG0757@2|Bacteria,1RDDT@1224|Proteobacteria,2VR4Y@28216|Betaproteobacteria,44VUG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
REGS1_k127_3196425_5	580332.Slit_2854	3.638e-63	219.0	COG0511@1|root,COG0511@2|Bacteria,1RCXA@1224|Proteobacteria,2VR5S@28216|Betaproteobacteria,44VSU@713636|Nitrosomonadales	28216|Betaproteobacteria	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
REGS1_k127_3196425_0	1485544.JQKP01000002_gene1516	1.655e-278	860.0	COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,2VISB@28216|Betaproteobacteria,44VMS@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM Carbamoyl-phosphate synthase L chain ATP-binding	accC	GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
REGS1_k127_3196425_2	395494.Galf_2883	3.581e-131	426.0	COG2264@1|root,COG2264@2|Bacteria,1MUPC@1224|Proteobacteria,2VH76@28216|Betaproteobacteria,44V4S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L11 methyltransferase (PrmA)	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
REGS1_k127_3196425_3	580332.Slit_2858	7.797e-68	241.0	2A4J7@1|root,30T5U@2|Bacteria,1RGAU@1224|Proteobacteria,2VU2M@28216|Betaproteobacteria,44W3F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3426)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3426,zinc_ribbon_4,zinc_ribbon_5
REGS1_k127_3257826_8	580332.Slit_1039	4.393e-123	402.0	COG1162@1|root,COG1162@2|Bacteria,1MUEF@1224|Proteobacteria,2VINY@28216|Betaproteobacteria,44UZ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
REGS1_k127_3257826_11	580332.Slit_1040	1.678e-52	187.0	COG2154@1|root,COG2154@2|Bacteria,1MZ5Q@1224|Proteobacteria,2VVZF@28216|Betaproteobacteria	28216|Betaproteobacteria	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
REGS1_k127_3257826_13	1485544.JQKP01000018_gene574	2.499e-28	118.0	COG3474@1|root,COG3474@2|Bacteria,1NIH9@1224|Proteobacteria,2WHPP@28216|Betaproteobacteria,44W35@713636|Nitrosomonadales	28216|Betaproteobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
REGS1_k127_3257826_3	1485544.JQKP01000018_gene573	8.047e-183	580.0	COG0501@1|root,COG0501@2|Bacteria,1MUXT@1224|Proteobacteria,2VI1Y@28216|Betaproteobacteria,44VFZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	CAAX prenyl protease N-terminal, five membrane helices	htpX_2	-	3.4.24.84	ko:K06013	ko00900,ko01130,map00900,map01130	-	R09845	RC00141	ko00000,ko00001,ko01000,ko01002,ko04147	-	-	-	Peptidase_M48,Peptidase_M48_N
REGS1_k127_3257826_10	395494.Galf_2165	4.404e-98	322.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,2VIA2@28216|Betaproteobacteria,44VDX@713636|Nitrosomonadales	28216|Betaproteobacteria	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
REGS1_k127_3257826_7	1485544.JQKP01000018_gene571	2.704e-126	415.0	COG1819@1|root,COG1819@2|Bacteria,1MVJM@1224|Proteobacteria,2VME8@28216|Betaproteobacteria,44V3H@713636|Nitrosomonadales	28216|Betaproteobacteria	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3257826_12	517417.Cpar_0023	4.513e-30	126.0	2EPSP@1|root,33HD6@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
REGS1_k127_3257826_6	1101195.Meth11DRAFT_1918	2.738e-128	419.0	COG0276@1|root,COG0276@2|Bacteria,1MVR1@1224|Proteobacteria,2VH7Z@28216|Betaproteobacteria,2KKWT@206350|Nitrosomonadales	206350|Nitrosomonadales	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
REGS1_k127_3257826_5	580332.Slit_1047	4.208e-174	550.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,2VHCK@28216|Betaproteobacteria,44W96@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
REGS1_k127_3257826_9	1485544.JQKP01000007_gene1977	1.734e-113	379.0	COG0061@1|root,COG0061@2|Bacteria,1MUBC@1224|Proteobacteria,2VIV0@28216|Betaproteobacteria,44VMV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
REGS1_k127_3257826_1	580332.Slit_1049	1.563e-246	771.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,2VHHA@28216|Betaproteobacteria,44VHC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
REGS1_k127_3257826_0	580332.Slit_1449	2.628e-281	888.0	COG1729@1|root,COG1729@2|Bacteria,1MZ7N@1224|Proteobacteria,2VNYC@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3257826_2	580332.Slit_1448	5.162e-218	698.0	COG0484@1|root,COG0484@2|Bacteria,1Q629@1224|Proteobacteria,2VJ8G@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
REGS1_k127_3257826_4	580332.Slit_1447	1.3e-180	566.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2WHYC@28216|Betaproteobacteria,44WNC@713636|Nitrosomonadales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
REGS1_k127_3343002_2	1123487.KB892834_gene2620	1.099e-15	81.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2VISD@28216|Betaproteobacteria,2KUFR@206389|Rhodocyclales	206389|Rhodocyclales	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
REGS1_k127_3343002_1	580332.Slit_2287	3.974e-60	211.0	2E3EJ@1|root,32YDJ@2|Bacteria,1N8MS@1224|Proteobacteria,2VW4J@28216|Betaproteobacteria,44WH3@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3343002_0	580332.Slit_2286	1.238e-182	580.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,44V9M@713636|Nitrosomonadales	28216|Betaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
REGS1_k127_3343002_3	580332.Slit_2285	0.0003061	43.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria,44WEK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Bacterial protein of unknown function (DUF899)	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_3382366_2	580332.Slit_2868	2.54e-112	368.0	COG3001@1|root,COG3001@2|Bacteria,1MVHX@1224|Proteobacteria,2VN04@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
REGS1_k127_3382366_1	580332.Slit_2866	8.27e-158	502.0	COG0524@1|root,COG0524@2|Bacteria,1PDQE@1224|Proteobacteria,2VHMF@28216|Betaproteobacteria,44V4U@713636|Nitrosomonadales	28216|Betaproteobacteria	G	pfkB family carbohydrate kinase	adoK	-	2.7.1.15,2.7.1.20	ko:K00852,ko:K00856	ko00030,ko00230,ko01100,map00030,map00230,map01100	-	R00185,R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
REGS1_k127_3382366_4	1454004.AW11_01463	1.351e-12	77.0	COG5581@1|root,COG5581@2|Bacteria,1RBFR@1224|Proteobacteria,2VQWE@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility	ycgR	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR
REGS1_k127_3382366_3	640081.Dsui_0392	4.707e-43	162.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,2KWKX@206389|Rhodocyclales	206389|Rhodocyclales	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
REGS1_k127_3382366_0	1163617.SCD_n02778	3.826e-208	653.0	COG1003@1|root,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2VHQ6@28216|Betaproteobacteria	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPB	-	1.4.4.2	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	Aminotran_5,GDC-P
REGS1_k127_3443143_12	580332.Slit_0715	2.399e-17	87.0	28RKJ@1|root,2ZDZE@2|Bacteria,1P9QH@1224|Proteobacteria,2W6JD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3443143_13	1122933.JNIY01000003_gene312	7.08e-08	60.0	COG1215@1|root,COG1215@2|Bacteria,2GNPU@201174|Actinobacteria,4F2D0@85016|Cellulomonadaceae	201174|Actinobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
REGS1_k127_3443143_3	1116472.MGMO_133c00080	1.655e-86	288.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,1RRGB@1236|Gammaproteobacteria,1XGG9@135618|Methylococcales	135618|Methylococcales	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3443143_7	1116472.MGMO_133c00090	9.262e-50	182.0	COG3011@1|root,COG3011@2|Bacteria	2|Bacteria	CH	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
REGS1_k127_3443143_11	1357272.AVEO02000201_gene4125	1.033e-19	98.0	COG3011@1|root,COG3011@2|Bacteria,1N6AW@1224|Proteobacteria,1TEHK@1236|Gammaproteobacteria,1Z7IH@136849|Pseudomonas syringae group	1236|Gammaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3443143_5	857087.Metme_3245	2.441e-71	244.0	COG1090@1|root,COG1090@2|Bacteria,1P62R@1224|Proteobacteria	1224|Proteobacteria	S	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3443143_1	1116472.MGMO_133c00110	1.066e-118	389.0	COG0702@1|root,COG0702@2|Bacteria,1PGNB@1224|Proteobacteria,1RUX3@1236|Gammaproteobacteria,1XFGR@135618|Methylococcales	135618|Methylococcales	GM	epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3,NAD_binding_10
REGS1_k127_3443143_9	1116472.MGMO_133c00120	1.197e-37	145.0	COG0702@1|root,COG0702@2|Bacteria,1N5CF@1224|Proteobacteria	1224|Proteobacteria	GM	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_3
REGS1_k127_3443143_6	1116472.MGMO_133c00130	2.029e-60	216.0	COG5528@1|root,COG5528@2|Bacteria,1RDUE@1224|Proteobacteria,1S5XB@1236|Gammaproteobacteria,1XFJB@135618|Methylococcales	135618|Methylococcales	S	Predicted integral membrane protein (DUF2269)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2269
REGS1_k127_3443143_8	580332.Slit_2019	6.697e-39	148.0	2C9QX@1|root,316K7@2|Bacteria,1PXQK@1224|Proteobacteria,2VWP4@28216|Betaproteobacteria	580332.Slit_2019|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3443143_14	877424.ATWC01000038_gene936	0.0008502	49.0	COG2843@1|root,COG2843@2|Bacteria,1V20N@1239|Firmicutes,24AI2@186801|Clostridia,27M7I@186928|unclassified Lachnospiraceae	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
REGS1_k127_3443143_4	292.DM42_6005	4.778e-82	278.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,2VQH1@28216|Betaproteobacteria,1KGNN@119060|Burkholderiaceae	28216|Betaproteobacteria	T	Transcriptional regulatory protein, C terminal	creB	-	-	ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_3443143_0	903818.KI912268_gene2803	1.003e-151	493.0	COG0642@1|root,COG2205@2|Bacteria	903818.KI912268_gene2803|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3443143_2	62928.azo0702	2.746e-114	383.0	COG4452@1|root,COG4452@2|Bacteria,1MVVR@1224|Proteobacteria,2VIXN@28216|Betaproteobacteria,2KV6G@206389|Rhodocyclales	206389|Rhodocyclales	V	Inner membrane protein CreD	-	-	-	ko:K06143	-	-	-	-	ko00000	-	-	-	CreD
REGS1_k127_3448010_6	648757.Rvan_1959	1.524e-52	186.0	2DBX8@1|root,2ZBN7@2|Bacteria,1RABM@1224|Proteobacteria,2U5PN@28211|Alphaproteobacteria,3N8F5@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function, DUF269	-	-	-	-	-	-	-	-	-	-	-	-	DUF269
REGS1_k127_3448010_11	748247.AZKH_0779	3.999e-19	89.0	COG5420@1|root,COG5420@2|Bacteria,1N74Y@1224|Proteobacteria,2VVVF@28216|Betaproteobacteria,2KZKV@206389|Rhodocyclales	206389|Rhodocyclales	S	Rop-like	-	-	-	-	-	-	-	-	-	-	-	-	Rop-like
REGS1_k127_3448010_10	648757.Rvan_1961	2.363e-23	103.0	COG1143@1|root,COG1143@2|Bacteria,1N1SG@1224|Proteobacteria,2TWG5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Ferredoxin III	fdxB	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7
REGS1_k127_3448010_9	748247.AZKH_4087	3.757e-43	166.0	2BDS5@1|root,327FW@2|Bacteria,1N15E@1224|Proteobacteria,2VUB3@28216|Betaproteobacteria,2KX42@206389|Rhodocyclales	206389|Rhodocyclales	S	NifQ	-	-	-	ko:K15790	-	-	-	-	ko00000	-	-	-	NifQ
REGS1_k127_3448010_5	398767.Glov_0124	4.623e-53	190.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,42TNE@68525|delta/epsilon subdivisions	1224|Proteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	2.3.1.57	ko:K22441	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
REGS1_k127_3448010_2	1122236.KB905142_gene387	1.695e-81	282.0	COG0725@1|root,COG0725@2|Bacteria,1MVNA@1224|Proteobacteria,2VJEC@28216|Betaproteobacteria,2KN5C@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
REGS1_k127_3448010_12	870187.Thini_0348	4.235e-18	89.0	2EBC7@1|root,335CY@2|Bacteria,1NFCS@1224|Proteobacteria,1SDGF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3448010_4	1116472.MGMO_18c00260	3.377e-59	210.0	297UU@1|root,2ZV1D@2|Bacteria,1MXFE@1224|Proteobacteria,1S5IT@1236|Gammaproteobacteria,1XFVB@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3448010_8	1116472.MGMO_11c00460	1.55e-43	160.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,1S8U3@1236|Gammaproteobacteria,1XFHS@135618|Methylococcales	135618|Methylococcales	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3448010_7	395495.Lcho_1371	1.897e-49	177.0	COG2440@1|root,COG2440@2|Bacteria,1RHTX@1224|Proteobacteria,2VSXZ@28216|Betaproteobacteria,1KM0P@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Could be a 3Fe-4S cluster-containing protein	fixX	-	-	ko:K03855	-	-	-	-	ko00000	-	-	-	ETF_QO
REGS1_k127_3448010_0	748247.AZKH_4100	1.222e-231	721.0	COG0644@1|root,COG0644@2|Bacteria,1MVU6@1224|Proteobacteria,2VH37@28216|Betaproteobacteria,2KU8X@206389|Rhodocyclales	28216|Betaproteobacteria	C	FAD dependent oxidoreductase	fixC	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,FAD_oxidored,GIDA
REGS1_k127_3448010_1	748247.AZKH_4101	1.019e-176	559.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,2VJWA@28216|Betaproteobacteria,2KUTZ@206389|Rhodocyclales	28216|Betaproteobacteria	C	Electron transfer flavoprotein domain	fixB	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
REGS1_k127_3448010_3	864073.HFRIS_009605	3.63e-61	214.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,2VN3Q@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Electron transfer flavoprotein	fixA	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
REGS1_k127_3532378_7	580332.Slit_0625	2.256e-75	254.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,44VGH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
REGS1_k127_3532378_3	1485544.JQKP01000011_gene776	2.218e-163	521.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VHX2@28216|Betaproteobacteria,44V69@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_3532378_9	395494.Galf_2163	1.562e-45	170.0	COG0589@1|root,COG0589@2|Bacteria,1N02E@1224|Proteobacteria,2VU60@28216|Betaproteobacteria,44W1F@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
REGS1_k127_3532378_10	1485544.JQKP01000003_gene237	7.942e-27	117.0	COG3038@1|root,COG3038@2|Bacteria,1PIVP@1224|Proteobacteria,2W7F3@28216|Betaproteobacteria,44VYF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prokaryotic cytochrome b561	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_3532378_8	580332.Slit_0334	2.259e-59	211.0	COG1514@1|root,COG1514@2|Bacteria,1RDB2@1224|Proteobacteria,2VTZU@28216|Betaproteobacteria,44WH9@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
REGS1_k127_3532378_0	1485544.JQKP01000002_gene1360	0.0	2139.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,2VHYU@28216|Betaproteobacteria,44VCD@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF3400)	glpCD	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3400,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_8
REGS1_k127_3532378_5	580332.Slit_0332	4.029e-116	392.0	2A8Z1@1|root,30Y2U@2|Bacteria,1PJYG@1224|Proteobacteria,2VJ83@28216|Betaproteobacteria,44W4N@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3532378_4	395494.Galf_0445	7.926e-163	521.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2VJ9G@28216|Betaproteobacteria,44V4R@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM peptidase S1 and S6 chymotrypsin Hap	degQ	-	-	ko:K04691,ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_3532378_6	580332.Slit_0636	3.089e-114	372.0	COG0327@1|root,COG0327@2|Bacteria,1MVUN@1224|Proteobacteria,2VIX1@28216|Betaproteobacteria,44V8N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	NIF3 (NGG1p interacting factor 3)	ybgI	-	-	-	-	-	-	-	-	-	-	-	NIF3
REGS1_k127_3532378_2	580332.Slit_1874	5.163e-167	534.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_10,Fer4_18,Fer4_5,FixG_C
REGS1_k127_3532378_1	580332.Slit_2567	0.0	1740.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,2VH3F@28216|Betaproteobacteria,44VF6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
REGS1_k127_3537446_27	580332.Slit_1018	2.876e-46	173.0	COG0671@1|root,COG0671@2|Bacteria,1PSM7@1224|Proteobacteria,2WB4I@28216|Betaproteobacteria,44WMP@713636|Nitrosomonadales	28216|Betaproteobacteria	I	SMART phosphoesterase PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_3537446_19	580332.Slit_1019	5.191e-87	290.0	COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,2VPZU@28216|Betaproteobacteria,44VS5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF520)	yajQ	-	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
REGS1_k127_3537446_21	580332.Slit_1020	3.308e-59	205.0	COG3123@1|root,COG3123@2|Bacteria,1MZ8N@1224|Proteobacteria,2VSCI@28216|Betaproteobacteria,44W28@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions	ppnP	-	2.4.2.1,2.4.2.2	ko:K09913	ko00230,ko00240,map00230,map00240	-	R01561,R01570,R01863,R01876,R02147,R02296,R02297	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	DUF1255
REGS1_k127_3537446_4	580332.Slit_1022	3.479e-257	794.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2VJ7Z@28216|Betaproteobacteria,44V8H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
REGS1_k127_3537446_11	1485544.JQKP01000018_gene592	2.319e-189	595.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,2VIVG@28216|Betaproteobacteria,44VFG@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_3537446_10	1485544.JQKP01000018_gene593	4.739e-207	649.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2VHEB@28216|Betaproteobacteria,44VA2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_3537446_30	580332.Slit_1025	2.574e-32	128.0	COG0268@1|root,COG0268@2|Bacteria,1MZ94@1224|Proteobacteria,2VTYY@28216|Betaproteobacteria,44W0I@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
REGS1_k127_3537446_3	580332.Slit_1028	8.072e-259	805.0	COG0728@1|root,COG0728@2|Bacteria,1MUH0@1224|Proteobacteria,2VHTQ@28216|Betaproteobacteria,44V0N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
REGS1_k127_3537446_14	580332.Slit_1030	2.239e-158	503.0	COG0583@1|root,COG0583@2|Bacteria,1MU8N@1224|Proteobacteria,2VHQY@28216|Betaproteobacteria,44V21@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LysR substrate binding domain	-	-	-	ko:K13634	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
REGS1_k127_3537446_15	1485544.JQKP01000003_gene205	3.138e-116	379.0	COG0730@1|root,COG0730@2|Bacteria,1MWX2@1224|Proteobacteria,2VMUD@28216|Betaproteobacteria,44VN0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
REGS1_k127_3537446_1	580332.Slit_1032	3.081e-301	939.0	COG0155@1|root,COG0155@2|Bacteria,1MVVB@1224|Proteobacteria,2VIYX@28216|Betaproteobacteria,44VXW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein	cysI	-	1.8.1.2,1.8.7.1	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858,R00859,R03600	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
REGS1_k127_3537446_16	395494.Galf_1979	7.685e-116	376.0	COG0175@1|root,COG0175@2|Bacteria,1MXUR@1224|Proteobacteria,2VIR0@28216|Betaproteobacteria,44V6T@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
REGS1_k127_3537446_12	580332.Slit_1034	7.483e-188	588.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,2VJH9@28216|Betaproteobacteria,44V50@713636|Nitrosomonadales	28216|Betaproteobacteria	EH	Phosphoadenosine phosphosulfate reductase family	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
REGS1_k127_3537446_6	1485544.JQKP01000003_gene209	3.821e-234	728.0	COG2895@1|root,COG2895@2|Bacteria,1MUD9@1224|Proteobacteria,2VHYV@28216|Betaproteobacteria,44VMN@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Elongation factor Tu GTP binding domain	cysN	-	2.7.7.4	ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_EFTU,GTP_EFTU_D2
REGS1_k127_3537446_25	187272.Mlg_0997	3.789e-47	173.0	COG2920@1|root,COG2920@2|Bacteria,1MWK9@1224|Proteobacteria,1RYE1@1236|Gammaproteobacteria,1WWZ5@135613|Chromatiales	135613|Chromatiales	P	TIGRFAM sulfur relay protein, TusE DsrC DsvC family	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
REGS1_k127_3537446_9	596154.Alide2_2495	1.736e-215	674.0	COG0446@1|root,COG0446@2|Bacteria,1PP77@1224|Proteobacteria,2W9FF@28216|Betaproteobacteria,4AA7E@80864|Comamonadaceae	28216|Betaproteobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
REGS1_k127_3537446_8	580332.Slit_1674	2.664e-222	699.0	COG1797@1|root,COG1797@2|Bacteria,1MV7Z@1224|Proteobacteria,2VI93@28216|Betaproteobacteria,44WDW@713636|Nitrosomonadales	28216|Betaproteobacteria	H	AAA domain	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
REGS1_k127_3537446_13	580332.Slit_1675	6.208e-183	579.0	COG5557@1|root,COG5557@2|Bacteria,1MXP7@1224|Proteobacteria,2VK76@28216|Betaproteobacteria,44WAJ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
REGS1_k127_3537446_17	1485544.JQKP01000005_gene322	7.603e-114	372.0	COG0437@1|root,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,2VKVM@28216|Betaproteobacteria,44W6H@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_11
REGS1_k127_3537446_28	1485544.JQKP01000005_gene321	1.014e-44	166.0	2E6CU@1|root,3310G@2|Bacteria,1N0TM@1224|Proteobacteria,2VV3Z@28216|Betaproteobacteria,44WKR@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3537446_0	580332.Slit_1678	0.0	1117.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,44V9S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_20,Fer4_21,Fer4_7,Pyr_redox_2,Pyr_redox_3
REGS1_k127_3537446_2	580332.Slit_1679	7.598e-299	922.0	COG0247@1|root,COG0247@2|Bacteria,1NZIG@1224|Proteobacteria,2VNTI@28216|Betaproteobacteria,44WBR@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
REGS1_k127_3537446_18	580332.Slit_1680	4.514e-104	342.0	COG2181@1|root,COG2181@2|Bacteria,1R48S@1224|Proteobacteria,2VPFB@28216|Betaproteobacteria,44W95@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrate reductase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Nitrate_red_gam
REGS1_k127_3537446_22	1485544.JQKP01000005_gene317	3.38e-59	206.0	COG2920@1|root,COG2920@2|Bacteria,1RGVG@1224|Proteobacteria,2VSFJ@28216|Betaproteobacteria,44WGQ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
REGS1_k127_3537446_29	580332.Slit_1682	2.299e-38	145.0	COG2168@1|root,COG2168@2|Bacteria,1PTT8@1224|Proteobacteria,2VWF4@28216|Betaproteobacteria,44WHZ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrH like protein	-	-	-	ko:K07237	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DsrH
REGS1_k127_3537446_23	1485544.JQKP01000005_gene315	3.155e-57	201.0	COG2923@1|root,COG2923@2|Bacteria,1N8RV@1224|Proteobacteria,2VSQ5@28216|Betaproteobacteria,44WHC@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K07236	ko04122,map04122	-	-	-	ko00000,ko00001,ko03016	-	-	-	DrsE
REGS1_k127_3537446_20	580332.Slit_1684	7.978e-68	231.0	COG1553@1|root,COG1553@2|Bacteria,1N021@1224|Proteobacteria,2VR8N@28216|Betaproteobacteria,44WFW@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrE/DsrF-like family	-	-	-	ko:K07235	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE
REGS1_k127_3537446_7	580332.Slit_1685	4.527e-223	695.0	COG2221@1|root,COG2221@2|Bacteria,1MVZQ@1224|Proteobacteria,2VPBV@28216|Betaproteobacteria,44WDK@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11181	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
REGS1_k127_3537446_5	580332.Slit_1686	3.515e-247	769.0	COG2221@1|root,COG2221@2|Bacteria,1MWY5@1224|Proteobacteria,2VPWJ@28216|Betaproteobacteria,44W8G@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.8.99.5	ko:K11180	ko00633,ko00920,ko01100,ko01120,map00633,map00920,map01100,map01120	M00596	R00295,R00861,R08035	RC00065,RC01760	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
REGS1_k127_3537446_31	580332.Slit_1687	4.92e-21	93.0	2EMP6@1|root,33FBM@2|Bacteria,1NGBE@1224|Proteobacteria,2VYCB@28216|Betaproteobacteria,44WK7@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3537446_26	580332.Slit_1688	1.008e-46	175.0	2CARE@1|root,2Z8Q5@2|Bacteria,1R7S8@1224|Proteobacteria,2VVIY@28216|Betaproteobacteria,44WHH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cas6 Crispr	-	-	-	-	-	-	-	-	-	-	-	-	Cas6
REGS1_k127_3537446_24	1485544.JQKP01000005_gene309	5.338e-48	174.0	COG2920@1|root,COG2920@2|Bacteria,1N2HP@1224|Proteobacteria,2VVGF@28216|Betaproteobacteria,44WH7@713636|Nitrosomonadales	28216|Betaproteobacteria	P	DsrC like protein	-	-	-	ko:K11179	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DsrC
REGS1_k127_3537446_32	1485544.JQKP01000005_gene308	1.942e-08	56.0	COG0425@1|root,COG0425@2|Bacteria,1PX23@1224|Proteobacteria,2WCJT@28216|Betaproteobacteria,44W8S@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
REGS1_k127_3574355_1	580332.Slit_0712	0.0	1100.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria,44V4X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	AAA domain	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
REGS1_k127_3574355_0	580332.Slit_0711	0.0	1208.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,1MY2G@1224|Proteobacteria,2VJF3@28216|Betaproteobacteria,44VKM@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PD-(D/E)XK nuclease superfamily	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1
REGS1_k127_3574355_6	580332.Slit_0710	1.494e-54	192.0	COG1146@1|root,COG1146@2|Bacteria,1RH5I@1224|Proteobacteria,2VSJ0@28216|Betaproteobacteria,44WI9@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions	fdxA	-	-	ko:K05524	-	-	-	-	ko00000	-	-	-	DUF3470,Fer4,Fer4_4
REGS1_k127_3574355_8	1005048.CFU_2200	9.01e-50	183.0	COG0824@1|root,COG0824@2|Bacteria,1MYQQ@1224|Proteobacteria,2VTDQ@28216|Betaproteobacteria,477E2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
REGS1_k127_3574355_3	1005048.CFU_2199	3.045e-172	552.0	COG4191@1|root,COG4191@2|Bacteria,1R72V@1224|Proteobacteria,2VJVI@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_7TM
REGS1_k127_3574355_9	561230.PC1_3752	8.033e-47	181.0	2C5YQ@1|root,32QV6@2|Bacteria,1RM0V@1224|Proteobacteria,1S8EE@1236|Gammaproteobacteria,1MQN9@122277|Pectobacterium	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3574355_5	1163617.SCD_n00880	1.711e-87	293.0	COG0135@1|root,COG0135@2|Bacteria,1RA87@1224|Proteobacteria,2VPZV@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
REGS1_k127_3574355_2	395494.Galf_0499	1.871e-220	687.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,2VHV3@28216|Betaproteobacteria,44V9J@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_3574355_4	580332.Slit_2114	7.541e-136	437.0	COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,2VI78@28216|Betaproteobacteria,44UZC@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
REGS1_k127_3574355_7	395494.Galf_0501	2.526e-52	187.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,2VHEQ@28216|Betaproteobacteria,44VH8@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
REGS1_k127_3624876_10	580332.Slit_2551	5.029e-58	202.0	COG1156@1|root,COG1156@2|Bacteria,1QUQE@1224|Proteobacteria	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab
REGS1_k127_3624876_0	580332.Slit_2552	2.125e-320	987.0	COG1155@1|root,COG1155@2|Bacteria,1MWRR@1224|Proteobacteria,2W0G7@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATPsynthase alpha/beta subunit N-term extension	-	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
REGS1_k127_3624876_12	580332.Slit_2553	1.741e-56	203.0	COG1390@1|root,COG1390@2|Bacteria,1R8BT@1224|Proteobacteria,2W49R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	V-type proton ATPase subunit E	-	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	-
REGS1_k127_3624876_14	580332.Slit_2554	2.031e-37	152.0	COG1436@1|root,COG1436@2|Bacteria,1MZUE@1224|Proteobacteria,2W5EY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase (F/14-kDa) subunit	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_F
REGS1_k127_3624876_9	580332.Slit_2555	1.251e-66	229.0	COG0636@1|root,COG0636@2|Bacteria,1REA9@1224|Proteobacteria,2W4JN@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase subunit C	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
REGS1_k127_3624876_1	580332.Slit_2556	2.647e-254	799.0	COG1269@1|root,COG1269@2|Bacteria,1QGFB@1224|Proteobacteria,2W04K@28216|Betaproteobacteria	28216|Betaproteobacteria	C	V-type ATPase 116kDa subunit family	-	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
REGS1_k127_3624876_6	580332.Slit_2557	1.073e-131	428.0	COG1527@1|root,COG1527@2|Bacteria,1R7PV@1224|Proteobacteria,2W2GY@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase (C/AC39) subunit	-	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
REGS1_k127_3624876_15	580332.Slit_2558	1.664e-23	103.0	2BU1D@1|root,32PA2@2|Bacteria,1N4TV@1224|Proteobacteria,2W58Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3624876_16	1408473.JHXO01000001_gene2351	1.121e-22	98.0	COG3360@1|root,COG3360@2|Bacteria	2|Bacteria	P	Dodecin	secE2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
REGS1_k127_3624876_2	395494.Galf_0293	2.089e-196	618.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VHPE@28216|Betaproteobacteria,44VBF@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Type II secretion system F domain	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
REGS1_k127_3624876_4	580332.Slit_2700	1.587e-138	445.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,2VI08@28216|Betaproteobacteria,44VHU@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
REGS1_k127_3624876_11	640081.Dsui_1056	2.529e-57	206.0	COG0237@1|root,COG0237@2|Bacteria,1RCXT@1224|Proteobacteria,2VR8K@28216|Betaproteobacteria,2KW4Z@206389|Rhodocyclales	206389|Rhodocyclales	F	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
REGS1_k127_3624876_7	1485544.JQKP01000007_gene2021	7.782e-111	363.0	COG4582@1|root,COG4582@2|Bacteria,1MW69@1224|Proteobacteria,2VIIG@28216|Betaproteobacteria,44VMD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity	zapD	-	-	ko:K18778	-	-	-	-	ko00000,ko03036	-	-	-	ZapD
REGS1_k127_3624876_17	335283.Neut_1047	1.819e-19	89.0	COG3024@1|root,COG3024@2|Bacteria,1NGJ8@1224|Proteobacteria,2VXRV@28216|Betaproteobacteria,373MY@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase	yacG	-	-	ko:K09862	-	-	-	-	ko00000	-	-	-	YacG
REGS1_k127_3624876_5	580332.Slit_2704	3.329e-137	443.0	COG0352@1|root,COG0494@1|root,COG0352@2|Bacteria,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,2VHTP@28216|Betaproteobacteria,44V8D@713636|Nitrosomonadales	28216|Betaproteobacteria	HL	Thiamine monophosphate synthase	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,TMP-TENI
REGS1_k127_3624876_13	1485544.JQKP01000002_gene1655	1.613e-54	193.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,44VWI@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
REGS1_k127_3624876_8	580332.Slit_0347	3.598e-77	263.0	COG0344@1|root,COG0344@2|Bacteria,1RD4Z@1224|Proteobacteria,2VQ10@28216|Betaproteobacteria,44VQ7@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
REGS1_k127_3624876_3	580332.Slit_0348	4.455e-166	529.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,44VK7@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_3624876_18	580332.Slit_2505	1.93e-13	72.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,2VIN7@28216|Betaproteobacteria,44V9E@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Indole-3-glycerol phosphate synthase	trpC	GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
REGS1_k127_3636572_1	1485544.JQKP01000007_gene1998	1.837e-162	518.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,44V1I@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
REGS1_k127_3636572_0	1485544.JQKP01000007_gene1999	1.265e-185	591.0	COG0486@1|root,COG0486@2|Bacteria,1MUCQ@1224|Proteobacteria,2VHCJ@28216|Betaproteobacteria,44V9H@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
REGS1_k127_3636572_3	1121451.DESAM_21635	2.157e-33	132.0	2C82G@1|root,32RK9@2|Bacteria,1MZV5@1224|Proteobacteria,42U4W@68525|delta/epsilon subdivisions,2WQ9S@28221|Deltaproteobacteria,2MCV4@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
REGS1_k127_3636572_2	1485544.JQKP01000012_gene2172	6.661e-97	319.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,44V4F@713636|Nitrosomonadales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
REGS1_k127_368187_22	1048983.EL17_18840	3.841e-20	94.0	2E3PY@1|root,32YMY@2|Bacteria,4NVJZ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_368187_0	1485544.JQKP01000012_gene2173	0.0	1120.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VIA1@28216|Betaproteobacteria,44V8Q@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	spoT	-	2.7.6.5,3.1.7.2	ko:K01139	ko00230,map00230	-	R00336,R00429	RC00002,RC00078	ko00000,ko00001,ko01000,ko03009	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
REGS1_k127_368187_20	1485544.JQKP01000012_gene2174	4.736e-32	125.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,2VVUH@28216|Betaproteobacteria,44W31@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
REGS1_k127_368187_18	580332.Slit_0400	1.031e-83	295.0	COG0194@1|root,COG0194@2|Bacteria,1MW92@1224|Proteobacteria,2VPCK@28216|Betaproteobacteria,44VSD@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
REGS1_k127_368187_10	580332.Slit_0401	1.075e-124	405.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,2VIFC@28216|Betaproteobacteria,44VKK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
REGS1_k127_368187_15	580332.Slit_0402	1.043e-101	339.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,2VIAV@28216|Betaproteobacteria,44WCA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART protein phosphatase 2C domain protein	pphA	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
REGS1_k127_368187_9	580332.Slit_0403	4.471e-127	410.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,2VIGI@28216|Betaproteobacteria,44V1Y@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
REGS1_k127_368187_14	395494.Galf_0394	2.997e-105	344.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,2VQ1Z@28216|Betaproteobacteria,44VFE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
REGS1_k127_368187_5	580332.Slit_0405	2.621e-206	647.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,2VHBB@28216|Betaproteobacteria,44V6C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	hemN2	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_368187_24	287.DR97_2225	2.499e-05	52.0	2E4IS@1|root,32ZDU@2|Bacteria,1N7N3@1224|Proteobacteria,1S6R3@1236|Gammaproteobacteria,1YJX6@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	psiF repeat	psiF	-	-	-	-	-	-	-	-	-	-	-	PsiF_repeat
REGS1_k127_368187_13	580332.Slit_0408	2.329e-106	349.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,2VJN2@28216|Betaproteobacteria,44V2E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
REGS1_k127_368187_8	580332.Slit_0409	6.185e-146	466.0	COG2022@1|root,COG2022@2|Bacteria,1N0N5@1224|Proteobacteria,2VJ8T@28216|Betaproteobacteria,44VMJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
REGS1_k127_368187_21	1485544.JQKP01000002_gene1605	1.167e-21	95.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,2WARD@28216|Betaproteobacteria,44W4B@713636|Nitrosomonadales	28216|Betaproteobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_368187_11	580332.Slit_1169	2.456e-117	384.0	COG0697@1|root,COG0697@2|Bacteria,1MWSU@1224|Proteobacteria,2VHP3@28216|Betaproteobacteria	28216|Betaproteobacteria	EG	of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_368187_12	580332.Slit_0422	2.245e-107	352.0	COG0664@1|root,COG0664@2|Bacteria,1MVGE@1224|Proteobacteria,2VH04@28216|Betaproteobacteria,44VPR@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	fnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_368187_3	580332.Slit_0423	3.514e-247	769.0	COG0635@1|root,COG0635@2|Bacteria,1MV1I@1224|Proteobacteria,2VJ1F@28216|Betaproteobacteria,44V78@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the anaerobic coproporphyrinogen-III oxidase family	hemN	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
REGS1_k127_368187_4	580332.Slit_0424	7.32e-231	718.0	COG2070@1|root,COG2070@2|Bacteria,1N52W@1224|Proteobacteria,2VJ45@28216|Betaproteobacteria,44VCF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Nitronate monooxygenase	-	-	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
REGS1_k127_368187_2	580332.Slit_0426	1.187e-248	787.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,2VI5J@28216|Betaproteobacteria,44W58@713636|Nitrosomonadales	28216|Betaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
REGS1_k127_368187_7	580332.Slit_0427	2.345e-159	511.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,2VH21@28216|Betaproteobacteria,44VDA@713636|Nitrosomonadales	28216|Betaproteobacteria	L	endonuclease III	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
REGS1_k127_368187_19	580332.Slit_0467	7.746e-34	132.0	COG2827@1|root,COG2827@2|Bacteria,1N6PA@1224|Proteobacteria,2VWG2@28216|Betaproteobacteria,44W37@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Excinuclease ABC C subunit domain protein	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
REGS1_k127_368187_6	1163617.SCD_n02569	1.102e-187	587.0	COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,2VIQX@28216|Betaproteobacteria	28216|Betaproteobacteria	J	glycyl-tRNA synthetase alpha subunit	glyQ	-	6.1.1.14	ko:K01878	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2e
REGS1_k127_368187_1	1304883.KI912532_gene1539	7.023e-296	923.0	COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,2VICG@28216|Betaproteobacteria,2KUWE@206389|Rhodocyclales	206389|Rhodocyclales	J	Glycyl-tRNA synthetase beta subunit	glyS	-	6.1.1.14	ko:K01879	ko00970,map00970	M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_1,tRNA_synt_2f
REGS1_k127_368187_16	580332.Slit_0470	1.39e-87	291.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2VQ49@28216|Betaproteobacteria,44VFT@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Polynucleotide kinase 3 phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_like,PNK3P
REGS1_k127_368187_17	580332.Slit_0471	7.307e-87	289.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,2VNAX@28216|Betaproteobacteria,44VFK@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Phosphate acyltransferases	nlaB	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_3708575_5	580332.Slit_1856	8.929e-103	336.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VHS7@28216|Betaproteobacteria,44V1M@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
REGS1_k127_3708575_15	62928.azo0125	4.391e-19	89.0	COG3070@1|root,COG3070@2|Bacteria,1NEFA@1224|Proteobacteria,2VYN2@28216|Betaproteobacteria	28216|Betaproteobacteria	K	TfoX C-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C
REGS1_k127_3708575_4	1123392.AQWL01000002_gene1764	5.583e-103	342.0	COG0010@1|root,COG0010@2|Bacteria,1MVFH@1224|Proteobacteria,2VJU2@28216|Betaproteobacteria,1KS02@119069|Hydrogenophilales	119069|Hydrogenophilales	E	Arginase family	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
REGS1_k127_3708575_17	1286631.X805_25850	4.284e-06	53.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VQID@28216|Betaproteobacteria,1KKNI@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Phospholipase/Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
REGS1_k127_3708575_13	243233.MCA0616	1.303e-27	124.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	Z012_00180	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
REGS1_k127_3708575_2	1485544.JQKP01000001_gene879	4.713e-201	637.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2VISD@28216|Betaproteobacteria,44VAU@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM membrane bound O-acyl transferase MBOAT family protein	pacA	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
REGS1_k127_3708575_10	76114.ebA3879	1.796e-74	255.0	COG1182@1|root,COG1182@2|Bacteria,1P59R@1224|Proteobacteria,2VK5E@28216|Betaproteobacteria,2KVXY@206389|Rhodocyclales	206389|Rhodocyclales	C	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity	azoR	-	-	ko:K01118	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_2
REGS1_k127_3708575_6	1502852.FG94_05063	6.326e-100	332.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2VIC3@28216|Betaproteobacteria,47609@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	ygiD	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
REGS1_k127_3708575_9	1123393.KB891333_gene2619	4.383e-83	286.0	COG0400@1|root,COG0400@2|Bacteria,1RA02@1224|Proteobacteria,2VQID@28216|Betaproteobacteria	28216|Betaproteobacteria	S	phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
REGS1_k127_3708575_1	580332.Slit_1331	2.752e-272	840.0	COG1066@1|root,COG1066@2|Bacteria,1MUJQ@1224|Proteobacteria,2VH93@28216|Betaproteobacteria,44VI7@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
REGS1_k127_3708575_11	1122194.AUHU01000026_gene85	9.854e-45	167.0	COG2303@1|root,COG2303@2|Bacteria,1RH5U@1224|Proteobacteria,1S60X@1236|Gammaproteobacteria,467QF@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3708575_0	580332.Slit_1326	1.282e-287	889.0	COG2509@1|root,COG2509@2|Bacteria,1MV6P@1224|Proteobacteria,2VHGJ@28216|Betaproteobacteria,44V1K@713636|Nitrosomonadales	28216|Betaproteobacteria	S	fad dependent oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	Amino_oxidase,Pyr_redox_2
REGS1_k127_3708575_12	580332.Slit_2246	8.534e-39	150.0	COG3094@1|root,COG3094@2|Bacteria,1MZN6@1224|Proteobacteria,2VUWN@28216|Betaproteobacteria,44WIJ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Invasion gene expression up-regulator, SirB	sirB	-	-	-	-	-	-	-	-	-	-	-	SirB
REGS1_k127_3708575_3	395494.Galf_2777	2.499e-124	405.0	COG1281@1|root,COG1281@2|Bacteria,1MUMU@1224|Proteobacteria,2VI8B@28216|Betaproteobacteria,44V88@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
REGS1_k127_3708575_7	1163617.SCD_n02348	3.56e-89	298.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2VQ09@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
REGS1_k127_3708575_8	1232683.ADIMK_0833	7.712e-85	286.0	COG2109@1|root,COG2109@2|Bacteria,1MUN6@1224|Proteobacteria,1RMH9@1236|Gammaproteobacteria,4642W@72275|Alteromonadaceae	1236|Gammaproteobacteria	H	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Co_AT_N,CobA_CobO_BtuR
REGS1_k127_3708575_14	395494.Galf_0021	6.97e-23	110.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,44VKI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
REGS1_k127_3708575_16	365046.Rta_34850	7.273e-16	83.0	28VC5@1|root,2ZHEW@2|Bacteria,1P4GX@1224|Proteobacteria,2W5EH@28216|Betaproteobacteria,4AIMX@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3752459_1	1485544.JQKP01000013_gene1791	1.47e-111	365.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,2WEJI@28216|Betaproteobacteria,44V2J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
REGS1_k127_3752459_3	580332.Slit_1296	3.655e-80	272.0	COG0242@1|root,COG0242@2|Bacteria,1R9XK@1224|Proteobacteria,2VQ0U@28216|Betaproteobacteria,44VSV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
REGS1_k127_3752459_2	580332.Slit_1295	3.436e-104	346.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,44VB8@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphorylase superfamily	mtaP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_3752459_0	1005048.CFU_3705	0.0	1354.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,4736T@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_3752459_4	795666.MW7_2363	2.233e-68	238.0	COG0745@1|root,COG0745@2|Bacteria,1MY5Y@1224|Proteobacteria,2VI0W@28216|Betaproteobacteria,1K3A8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	response regulator	basR_3	-	-	ko:K02483,ko:K07666,ko:K07774	ko02020,ko02024,map02020,map02024	M00453,M00457	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_3782093_3	190486.XAC1912	4.7e-72	253.0	COG0515@1|root,COG0515@2|Bacteria	190486.XAC1912|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3782093_6	1249627.D779_0099	1.318e-11	70.0	2DREF@1|root,33BDW@2|Bacteria,1NH6T@1224|Proteobacteria,1SGD4@1236|Gammaproteobacteria,1X12J@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3782093_7	446466.Cfla_3133	8.247e-06	51.0	2EVD7@1|root,33NTQ@2|Bacteria,2IRUN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3782093_1	1121035.AUCH01000003_gene1219	4.948e-94	340.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K20975	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_3782093_4	397945.Aave_2063	6.268e-45	187.0	COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2202@1|root,COG3829@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2WGMB@28216|Betaproteobacteria,4AJYH@80864|Comamonadaceae	28216|Betaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11527	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_7,PAS_9,Reg_prop,Response_reg,Y_Y_Y,dCache_1
REGS1_k127_3782093_2	506534.Rhein_3512	7.612e-81	284.0	COG3203@1|root,COG3203@2|Bacteria,1R5CI@1224|Proteobacteria	1224|Proteobacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
REGS1_k127_3782093_5	1538295.JY96_06475	5.157e-31	127.0	COG0226@1|root,COG0226@2|Bacteria,1N7RX@1224|Proteobacteria,2VUXR@28216|Betaproteobacteria,1KPBZ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	ABC-type phosphate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3782093_8	1282362.AEAC466_16160	1.739e-05	54.0	COG3637@1|root,COG3637@2|Bacteria,1N6MW@1224|Proteobacteria,2UDM3@28211|Alphaproteobacteria,2KGWX@204458|Caulobacterales	204458|Caulobacterales	M	Outer membrane protein beta-barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
REGS1_k127_38286_2	580332.Slit_1171	9.94e-167	526.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,44VGD@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_38286_3	640081.Dsui_2113	2.337e-127	414.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,2VHZF@28216|Betaproteobacteria,2KVV1@206389|Rhodocyclales	206389|Rhodocyclales	E	Bacterial transferase hexapeptide (six repeats)	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep
REGS1_k127_38286_6	1485544.JQKP01000003_gene165	1.255e-26	110.0	COG1813@1|root,COG1813@2|Bacteria,1QUZG@1224|Proteobacteria,2WGMZ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
REGS1_k127_38286_1	1485544.JQKP01000003_gene164	3.987e-184	577.0	COG0664@1|root,COG0664@2|Bacteria,1MW6M@1224|Proteobacteria,2VHR8@28216|Betaproteobacteria	28216|Betaproteobacteria	T	signal-transduction protein containing cAMP-binding and CBS domains	mmpI	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_38286_0	583345.Mmol_0800	3.444e-219	694.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,2VIQW@28216|Betaproteobacteria,2KKT3@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
REGS1_k127_38286_4	580332.Slit_1170	3.436e-122	397.0	COG4340@1|root,COG4340@2|Bacteria,1R9YQ@1224|Proteobacteria,2VHC5@28216|Betaproteobacteria,44WAY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	2OG-Fe dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	2OG-Fe_Oxy_2
REGS1_k127_38286_7	1485544.JQKP01000003_gene182	2.866e-12	66.0	COG1897@1|root,COG1897@2|Bacteria,1MV64@1224|Proteobacteria,2VURW@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
REGS1_k127_38286_5	1000565.METUNv1_01576	1.373e-108	357.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,2KVR8@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_3840549_3	987059.RBXJA2T_15003	7.503e-15	74.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,2VJI3@28216|Betaproteobacteria,1KNEX@119065|unclassified Burkholderiales	28216|Betaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
REGS1_k127_3840549_1	395494.Galf_1921	5.199e-155	491.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,2VHKY@28216|Betaproteobacteria,44WC4@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Binding-protein-dependent transport system inner membrane component	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
REGS1_k127_3840549_2	395494.Galf_1922	5.96e-152	484.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2VI3S@28216|Betaproteobacteria,44W8N@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
REGS1_k127_3840549_0	395494.Galf_1923	1.089e-203	636.0	COG1118@1|root,COG1118@2|Bacteria,1QTTT@1224|Proteobacteria,2VH92@28216|Betaproteobacteria,44VUJ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TOBE-like domain	cysA	-	3.6.3.25	ko:K02045	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_3
REGS1_k127_3880596_4	395494.Galf_1709	2.594e-32	126.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,2VPZ0@28216|Betaproteobacteria,44W77@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
REGS1_k127_3880596_3	1485544.JQKP01000001_gene1204	1.489e-42	164.0	COG3448@1|root,COG3448@2|Bacteria,1MXJG@1224|Proteobacteria,2VJU5@28216|Betaproteobacteria,44W1J@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM HPP family protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS,HPP
REGS1_k127_3880596_1	580332.Slit_2248	1.616e-70	242.0	COG1495@1|root,COG1495@2|Bacteria,1RIJE@1224|Proteobacteria,2VREE@28216|Betaproteobacteria,44VV0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein	dsbB	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
REGS1_k127_3880596_5	748280.NH8B_3430	8.631e-27	111.0	COG2975@1|root,COG2975@2|Bacteria,1N7C1@1224|Proteobacteria,2VVQU@28216|Betaproteobacteria,2KRVE@206351|Neisseriales	206351|Neisseriales	S	Iron-sulphur cluster assembly	iscX	-	-	-	-	-	-	-	-	-	-	-	Fe-S_assembly
REGS1_k127_3880596_2	1169143.KB911034_gene1130	1.42e-51	184.0	COG0633@1|root,COG0633@2|Bacteria,1RHDC@1224|Proteobacteria,2VSQE@28216|Betaproteobacteria,1K7RJ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Ferredoxin, 2Fe-2S type, ISC system	fdx	-	-	ko:K04755	-	-	-	-	ko00000	-	-	-	Fer2
REGS1_k127_3880596_0	1485544.JQKP01000013_gene1803	5.163e-161	513.0	COG0443@1|root,COG0443@2|Bacteria,1MVQI@1224|Proteobacteria,2VHGV@28216|Betaproteobacteria,44VHV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB	hscA	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04044	-	-	-	-	ko00000,ko03110	1.A.33	-	-	HSP70
REGS1_k127_3885736_4	580332.Slit_2428	4.468e-86	287.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VKWZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Dehydrogenase	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
REGS1_k127_3885736_5	795666.MW7_1031	1.445e-74	255.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2VR4K@28216|Betaproteobacteria,1K18T@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
REGS1_k127_3885736_10	580332.Slit_1614	1.079e-31	126.0	2FBSW@1|root,343XP@2|Bacteria,1P3U4@1224|Proteobacteria,2W4AY@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3885736_7	1121035.AUCH01000004_gene351	2.395e-51	188.0	COG3034@1|root,COG3034@2|Bacteria,1MXY6@1224|Proteobacteria,2VTUE@28216|Betaproteobacteria	28216|Betaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_3885736_14	1250232.JQNJ01000001_gene1790	4.471e-11	70.0	COG0790@1|root,COG0790@2|Bacteria,4P4MM@976|Bacteroidetes,1I9PX@117743|Flavobacteriia	976|Bacteroidetes	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3885736_0	1485544.JQKP01000003_gene197	0.0	1062.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VHHU@28216|Betaproteobacteria,44V28@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
REGS1_k127_3885736_12	580332.Slit_1547	1.321e-18	89.0	290YX@1|root,2ZNKN@2|Bacteria,1PA5S@1224|Proteobacteria,2W6J1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_3885736_1	580332.Slit_0718	5.726e-188	592.0	COG1533@1|root,COG1533@2|Bacteria,1MW0H@1224|Proteobacteria,2VIYE@28216|Betaproteobacteria,44WA4@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Elongator protein 3, MiaB family, Radical SAM	splB	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
REGS1_k127_3885736_8	1123392.AQWL01000001_gene1691	1.149e-39	151.0	COG1974@1|root,COG1974@2|Bacteria,1MZFA@1224|Proteobacteria,2VU86@28216|Betaproteobacteria	28216|Betaproteobacteria	KT	Belongs to the peptidase S24 family	-	-	-	ko:K03503	-	-	-	-	ko00000,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
REGS1_k127_3885736_2	261292.Nit79A3_2298	5.189e-151	488.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,2VHHK@28216|Betaproteobacteria,3720G@32003|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DNA-repair protein, UmuC-like	rumB	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	DUF4113,IMS,IMS_C,IMS_HHH
REGS1_k127_3885736_6	706436.HMPREF9074_08996	1.006e-69	252.0	COG2843@1|root,COG2843@2|Bacteria,4NI5N@976|Bacteroidetes,1I6CZ@117743|Flavobacteriia,1EQ3C@1016|Capnocytophaga	976|Bacteroidetes	M	capsule biosynthesis protein CapA	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
REGS1_k127_3885736_9	1415755.JQLV01000001_gene2170	9.574e-35	134.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1XJPR@135619|Oceanospirillales	135619|Oceanospirillales	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
REGS1_k127_3885736_3	580332.Slit_0712	7.973e-134	435.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,2VI92@28216|Betaproteobacteria,44V4X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	AAA domain	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
REGS1_k127_4035006_2	1485544.JQKP01000002_gene1489	2.347e-92	311.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,2VNY1@28216|Betaproteobacteria,44V9Q@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	regB	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
REGS1_k127_4035006_1	580332.Slit_1175	6.606e-124	406.0	COG4313@1|root,COG4313@2|Bacteria,1R5Z9@1224|Proteobacteria,2VKTG@28216|Betaproteobacteria,44WK5@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Protein involved in meta-pathway of phenol degradation	-	-	-	-	-	-	-	-	-	-	-	-	Phenol_MetA_deg
REGS1_k127_4035006_5	580332.Slit_1321	6.966e-64	226.0	COG3658@1|root,COG3658@2|Bacteria,1RB03@1224|Proteobacteria,2VQQ7@28216|Betaproteobacteria,44WFY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
REGS1_k127_4035006_7	580332.Slit_1322	2.035e-46	174.0	2FG6B@1|root,3482S@2|Bacteria,1P2BQ@1224|Proteobacteria,2W87X@28216|Betaproteobacteria,44WHR@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4035006_8	580332.Slit_1323	1.175e-43	164.0	COG1858@1|root,COG1858@2|Bacteria,1QVT1@1224|Proteobacteria,2WGTP@28216|Betaproteobacteria,44WIA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Domain of unknown function (DUF1924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1924
REGS1_k127_4035006_4	580332.Slit_1324	1.064e-79	271.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria,44WF4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Dihaem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
REGS1_k127_4035006_0	580332.Slit_0650	2.408e-254	786.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,2VJ4F@28216|Betaproteobacteria,44V8Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
REGS1_k127_4035006_3	580332.Slit_0651	4.203e-80	270.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,2VR9P@28216|Betaproteobacteria,44VU0@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
REGS1_k127_4035006_6	395494.Galf_2346	9.611e-47	169.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,2VI9P@28216|Betaproteobacteria,44VG2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
REGS1_k127_4079765_8	1385517.N800_11095	6.925e-12	66.0	COG0633@1|root,COG1018@1|root,COG2346@1|root,COG0633@2|Bacteria,COG1018@2|Bacteria,COG2346@2|Bacteria,1REP4@1224|Proteobacteria,1T2XC@1236|Gammaproteobacteria,1XDHE@135614|Xanthomonadales	135614|Xanthomonadales	C	Bacterial-like globin	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin,FAD_binding_6,Fer2,NAD_binding_1
REGS1_k127_4079765_10	40215.BBOS01000010_gene3132	1.617e-09	61.0	COG1018@1|root,COG2346@1|root,COG1018@2|Bacteria,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	-	-	-	ko:K06886,ko:K07006	-	-	-	-	ko00000	-	-	-	Bac_globin,DUF4445,Fer2
REGS1_k127_4079765_0	580332.Slit_1383	2.148e-279	869.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,2VIBW@28216|Betaproteobacteria,44V5V@713636|Nitrosomonadales	28216|Betaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
REGS1_k127_4079765_2	580332.Slit_1381	6.116e-215	673.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VJXD@28216|Betaproteobacteria,44V3C@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
REGS1_k127_4079765_3	580332.Slit_1380	4.952e-136	445.0	COG0324@1|root,COG0324@2|Bacteria,1MUB2@1224|Proteobacteria,2VHEP@28216|Betaproteobacteria,44VBB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
REGS1_k127_4079765_6	1173023.KE650771_gene1644	1.594e-21	101.0	COG4276@1|root,COG4276@2|Bacteria,1G939@1117|Cyanobacteria,1JIIM@1189|Stigonemataceae	1117|Cyanobacteria	S	Pfam Polyketide cyclase dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4079765_9	1459636.NTE_03458	8.574e-11	66.0	COG0431@1|root,arCOG04624@2157|Archaea	2157|Archaea	S	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_4079765_5	378806.STAUR_3509	1.289e-48	175.0	COG0431@1|root,COG0431@2|Bacteria,1MXQ8@1224|Proteobacteria,433WV@68525|delta/epsilon subdivisions,2X8XD@28221|Deltaproteobacteria,2YXH7@29|Myxococcales	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_4079765_7	7668.SPU_019638-tr	1.405e-18	93.0	COG0666@1|root,KOG4177@2759|Eukaryota	2759|Eukaryota	I	spectrin binding	-	-	1.14.13.225	ko:K15502,ko:K19947	-	-	-	-	ko00000,ko01000,ko01009,ko03400,ko04131	-	-	-	Ank,Ank_2,Ank_3,Ank_4,Ank_5,ZU5
REGS1_k127_4079765_4	580332.Slit_1428	2.161e-135	433.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,2VHF4@28216|Betaproteobacteria,44VAT@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the ribose of guanosine 2251 in 23S rRNA	rlmB	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
REGS1_k127_4079765_1	580332.Slit_1404	1.224e-222	700.0	COG0664@1|root,COG0668@1|root,COG0664@2|Bacteria,COG0668@2|Bacteria,1R6J6@1224|Proteobacteria,2VPCU@28216|Betaproteobacteria,44W84@713636|Nitrosomonadales	28216|Betaproteobacteria	MT	MscS Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
REGS1_k127_4083813_20	580332.Slit_0138	1.412e-64	223.0	COG2891@1|root,COG2891@2|Bacteria,1RBNF@1224|Proteobacteria,2VQQ3@28216|Betaproteobacteria,44VW1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
REGS1_k127_4083813_3	580332.Slit_0139	4.578e-292	907.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,2VHBZ@28216|Betaproteobacteria,44VBN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
REGS1_k127_4083813_10	395494.Galf_2795	8.702e-170	540.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,2VH8Q@28216|Betaproteobacteria,44VDN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidoglycan polymerase that is essential for cell wall elongation	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
REGS1_k127_4083813_16	580332.Slit_0141	6.861e-100	335.0	COG0797@1|root,COG3087@1|root,COG0797@2|Bacteria,COG3087@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,44VIA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1,SPOR
REGS1_k127_4083813_23	1384054.N790_04950	1.373e-32	139.0	COG1714@1|root,COG4969@1|root,COG1714@2|Bacteria,COG4969@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1X5Z4@135614|Xanthomonadales	135614|Xanthomonadales	NU	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
REGS1_k127_4083813_25	1123253.AUBD01000002_gene1203	4.946e-27	123.0	COG1714@1|root,COG4969@1|root,COG1714@2|Bacteria,COG4969@2|Bacteria,1N1XF@1224|Proteobacteria,1SDY3@1236|Gammaproteobacteria,1X5Z4@135614|Xanthomonadales	135614|Xanthomonadales	NU	membrane protein domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339,RDD
REGS1_k127_4083813_17	1163617.SCD_n00466	3.514e-97	327.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,2VP72@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
REGS1_k127_4083813_9	580332.Slit_0256	4.976e-194	618.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,2VJKV@28216|Betaproteobacteria,44VAN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_4083813_6	580332.Slit_0255	2.716e-220	688.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,2VHNC@28216|Betaproteobacteria,44VIX@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
REGS1_k127_4083813_8	580332.Slit_0034	1.625e-198	629.0	COG0477@1|root,COG2814@2|Bacteria,1MUZ8@1224|Proteobacteria,2VI8P@28216|Betaproteobacteria,44VM1@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	ampG	-	-	ko:K08218	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.25	-	-	MFS_1
REGS1_k127_4083813_18	395494.Galf_0125	8.576e-94	310.0	COG0500@1|root,COG2226@2|Bacteria,1MVSY@1224|Proteobacteria,2VMPA@28216|Betaproteobacteria,44VF4@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Methionine biosynthesis protein MetW	metW	-	-	-	-	-	-	-	-	-	-	-	MetW
REGS1_k127_4083813_7	580332.Slit_0036	1.452e-207	649.0	COG2021@1|root,COG2021@2|Bacteria,1MVJV@1224|Proteobacteria,2VHU9@28216|Betaproteobacteria,44V9X@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine	metXS	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
REGS1_k127_4083813_15	666681.M301_0882	1.818e-102	351.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,2VH62@28216|Betaproteobacteria,2KKI5@206350|Nitrosomonadales	206350|Nitrosomonadales	T	Osmosensitive K channel His kinase sensor	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA
REGS1_k127_4083813_19	666681.M301_0881	2.516e-81	276.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,2VIM1@28216|Betaproteobacteria,2KKS0@206350|Nitrosomonadales	206350|Nitrosomonadales	T	PFAM response regulator receiver	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
REGS1_k127_4083813_4	666681.M301_0880	1.06e-263	825.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,2VH9I@28216|Betaproteobacteria,2KNHX@206350|Nitrosomonadales	206350|Nitrosomonadales	P	K+ potassium transporter	-	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
REGS1_k127_4083813_2	1485544.JQKP01000002_gene1562	3.139e-292	906.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,2VH9N@28216|Betaproteobacteria,44VJY@713636|Nitrosomonadales	28216|Betaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
REGS1_k127_4083813_24	305700.B447_01901	2.958e-31	126.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,2VU8W@28216|Betaproteobacteria,2KWVF@206389|Rhodocyclales	206389|Rhodocyclales	G	Phosphotransferase System	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
REGS1_k127_4083813_22	1485544.JQKP01000002_gene1564	9.306e-46	168.0	COG2893@1|root,COG2893@2|Bacteria,1RHH7@1224|Proteobacteria,2VT9I@28216|Betaproteobacteria,44W0H@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM PTS system fructose subfamily IIA component	manX	-	2.7.1.194	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.7.1	-	-	EIIA-man
REGS1_k127_4083813_12	580332.Slit_0101	2.863e-156	514.0	COG1477@1|root,COG1477@2|Bacteria,1MW6K@1224|Proteobacteria,2VPGP@28216|Betaproteobacteria,44VGN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	rnfF	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
REGS1_k127_4083813_5	1485544.JQKP01000002_gene1566	3.476e-238	740.0	COG0342@1|root,COG0342@2|Bacteria,1MVFS@1224|Proteobacteria,2VHD9@28216|Betaproteobacteria,44V1Q@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Glutamate-cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GshA
REGS1_k127_4083813_1	580332.Slit_0097	0.0	1010.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHGH@28216|Betaproteobacteria,44VKU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ABC transporter related	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_4083813_14	580332.Slit_0096	7.761e-111	363.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,2VQ46@28216|Betaproteobacteria,44UYG@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
REGS1_k127_4083813_13	1163407.UU7_11864	9.835e-152	503.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	ko:K04772	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
REGS1_k127_4083813_11	580332.Slit_0071	1.993e-157	499.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,2VIXE@28216|Betaproteobacteria,44UYK@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
REGS1_k127_4083813_21	1132855.KB913035_gene1182	5.718e-64	240.0	COG2202@1|root,COG3852@1|root,COG4191@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VI6T@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_9
REGS1_k127_4083813_0	697282.Mettu_4224	0.0	1299.0	COG1196@1|root,COG1352@1|root,COG2201@1|root,COG1196@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,1NQTI@1224|Proteobacteria,1T2RH@1236|Gammaproteobacteria,1XE6G@135618|Methylococcales	135618|Methylococcales	NT	PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase	-	-	-	-	-	-	-	-	-	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
REGS1_k127_4107802_2	580332.Slit_2180	1.156e-56	201.0	COG0534@1|root,COG0534@2|Bacteria,1MUAM@1224|Proteobacteria,2VH2B@28216|Betaproteobacteria	28216|Betaproteobacteria	V	Mate efflux family protein	norM	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
REGS1_k127_4107802_3	1121373.KB903624_gene2412	5.238e-07	58.0	2DT69@1|root,33IW5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4107802_1	580332.Slit_2778	1.114e-129	417.0	COG0330@1|root,COG0330@2|Bacteria,1MUM8@1224|Proteobacteria,2VHZW@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM band 7 protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_4107802_0	580332.Slit_2777	5.257e-207	653.0	COG1030@1|root,COG1030@2|Bacteria,1MUJN@1224|Proteobacteria,2VMUK@28216|Betaproteobacteria	28216|Betaproteobacteria	O	serine protease	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
REGS1_k127_4198383_5	395494.Galf_0623	8.216e-61	210.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria,44VJK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
REGS1_k127_4198383_1	580332.Slit_2361	1.712e-158	511.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,2VMDE@28216|Betaproteobacteria,44VJT@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
REGS1_k127_4198383_4	395494.Galf_0472	9.786e-76	261.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,2VRRA@28216|Betaproteobacteria,44VS9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
REGS1_k127_4198383_3	580332.Slit_2359	6.269e-95	319.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VJ2B@28216|Betaproteobacteria,44V3I@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
REGS1_k127_4198383_0	580332.Slit_2357	1.683e-174	565.0	COG0457@1|root,COG3071@1|root,COG0457@2|Bacteria,COG3071@2|Bacteria,1MYB8@1224|Proteobacteria,2VI6C@28216|Betaproteobacteria,44VNS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
REGS1_k127_4198383_6	580332.Slit_2356	1.996e-46	173.0	COG3017@1|root,COG3017@2|Bacteria,1N02T@1224|Proteobacteria,2VUIR@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein	lolB	-	-	ko:K02494	-	-	-	-	ko00000	-	-	-	LolB
REGS1_k127_4198383_2	472759.Nhal_0251	3.426e-133	429.0	COG1943@1|root,COG1943@2|Bacteria,1MX0E@1224|Proteobacteria,1RPJH@1236|Gammaproteobacteria,1WWU7@135613|Chromatiales	135613|Chromatiales	L	PFAM Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
REGS1_k127_4198383_7	580332.Slit_1605	1.204e-31	125.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VP2B@28216|Betaproteobacteria,44W71@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2	-	-	ABC_membrane,ABC_tran
REGS1_k127_4258561_4	114615.BRADO1382	5.955e-110	372.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CarboxypepD_reg,YARHG
REGS1_k127_4258561_2	114615.BRADO1383	2.744e-138	454.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria	1224|Proteobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
REGS1_k127_4258561_12	640511.BC1002_4970	2.81e-44	169.0	2B41E@1|root,31WRS@2|Bacteria,1P8VA@1224|Proteobacteria,2VSE9@28216|Betaproteobacteria,1K0YA@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4258561_11	1095769.CAHF01000015_gene2795	6.81e-47	172.0	COG4922@1|root,COG4922@2|Bacteria,1RDM5@1224|Proteobacteria,2VSBK@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
REGS1_k127_4258561_14	1288494.EBAPG3_27970	1.817e-41	158.0	2DMWA@1|root,32U36@2|Bacteria,1N1CC@1224|Proteobacteria,2VU4K@28216|Betaproteobacteria,3736Q@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4258561_9	595494.Tola_1512	1.598e-68	237.0	COG3832@1|root,COG3832@2|Bacteria,1RICZ@1224|Proteobacteria,1S9XH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2
REGS1_k127_4258561_10	595494.Tola_1511	1.111e-66	233.0	COG2834@1|root,COG2834@2|Bacteria,1RFBN@1224|Proteobacteria,1S7A5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1571
REGS1_k127_4258561_3	1163617.SCD_n01786	1.529e-137	446.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,2VIXM@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
REGS1_k127_4258561_1	395494.Galf_0613	7.4e-197	620.0	COG0477@1|root,COG2814@2|Bacteria,1QTWR@1224|Proteobacteria,2VIC5@28216|Betaproteobacteria,44VJQ@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	lplT	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_4258561_6	580332.Slit_2227	1.81e-103	342.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,2VPZQ@28216|Betaproteobacteria,44VSC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM phage SPO1 DNA polymerase-related protein	dpo	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_4258561_13	265072.Mfla_0413	1.5e-42	160.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,2VUIW@28216|Betaproteobacteria,2KMVP@206350|Nitrosomonadales	206350|Nitrosomonadales	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
REGS1_k127_4258561_7	580332.Slit_2229	3.599e-91	304.0	COG1214@1|root,COG1214@2|Bacteria,1MXPH@1224|Proteobacteria,2VQR7@28216|Betaproteobacteria,44VJ8@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glycoprotease family	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_4258561_8	1485544.JQKP01000002_gene1649	5.562e-82	274.0	COG0245@1|root,COG0245@2|Bacteria,1MVHA@1224|Proteobacteria,2VR7F@28216|Betaproteobacteria,44VPY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
REGS1_k127_4258561_5	395494.Galf_0608	1.411e-105	347.0	COG1211@1|root,COG1211@2|Bacteria,1MY3B@1224|Proteobacteria,2VMD6@28216|Betaproteobacteria,44VGQ@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60,4.6.1.12	ko:K00991,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
REGS1_k127_4258561_0	1485544.JQKP01000002_gene1598	0.0	1835.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,2VI7M@28216|Betaproteobacteria,44UYD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
REGS1_k127_4264368_0	1485544.JQKP01000008_gene1704	0.0	1103.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VKX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
REGS1_k127_4264368_3	395494.Galf_2723	9.528e-42	160.0	2DY16@1|root,347JT@2|Bacteria,1P2MN@1224|Proteobacteria,2W4PM@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4264368_2	395494.Galf_2722	7.745e-58	205.0	28WAT@1|root,2ZIB9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4264368_4	330214.NIDE0067	9.574e-35	134.0	COG0053@1|root,COG0053@2|Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4264368_1	1121918.ARWE01000001_gene3299	5.524e-85	289.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria	1224|Proteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5,Response_reg
REGS1_k127_4380327_1	580332.Slit_2844	0.0	1194.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,44VHM@713636|Nitrosomonadales	28216|Betaproteobacteria	L	UvrD-like helicase C-terminal domain	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_4380327_27	580332.Slit_0182	2.396e-24	109.0	COG3637@1|root,COG3637@2|Bacteria,1NIE3@1224|Proteobacteria,2VXMU@28216|Betaproteobacteria,44WMS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA_membrane
REGS1_k127_4380327_5	580332.Slit_1882	4.768e-288	892.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria,44V29@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
REGS1_k127_4380327_24	580332.Slit_2929	4.542e-34	138.0	COG0695@1|root,COG0695@2|Bacteria,1N7X3@1224|Proteobacteria,2VVPB@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Pfam Glutaredoxin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Glutaredoxin
REGS1_k127_4380327_4	1485544.JQKP01000012_gene2151	0.0	1061.0	COG0339@1|root,COG0339@2|Bacteria,1MU1K@1224|Proteobacteria,2VHPQ@28216|Betaproteobacteria,44VER@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
REGS1_k127_4380327_6	580332.Slit_2931	4.324e-241	752.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,2VH1E@28216|Betaproteobacteria,44V6X@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Amidohydrolase family	pyrX	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
REGS1_k127_4380327_11	580332.Slit_2932	1.815e-184	579.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,2VHG9@28216|Betaproteobacteria,44VME@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
REGS1_k127_4380327_20	580332.Slit_2933	3.482e-61	214.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,2VUH0@28216|Betaproteobacteria,44VTU@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yqgF	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
REGS1_k127_4380327_16	580332.Slit_2935	8.248e-88	295.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,2VJQA@28216|Betaproteobacteria,44VSQ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	algH	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
REGS1_k127_4380327_0	580332.Slit_2936	0.0	1695.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,44W8H@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine Phosphotransfer domain	pilL	-	-	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
REGS1_k127_4380327_10	1485544.JQKP01000007_gene2025	1.598e-190	616.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2VJBX@28216|Betaproteobacteria,44W5A@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	histidine kinase HAMP region domain protein	pilJ	-	-	ko:K02660,ko:K03406	ko02020,ko02025,ko02030,map02020,map02025,map02030	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	MCPsignal,PilJ
REGS1_k127_4380327_22	580332.Slit_2938	9.007e-52	187.0	COG0835@1|root,COG0835@2|Bacteria,1N07Q@1224|Proteobacteria,2VU6N@28216|Betaproteobacteria,44WGG@713636|Nitrosomonadales	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	pilI	-	-	ko:K02659	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	CheW
REGS1_k127_4380327_21	580332.Slit_2939	2.604e-56	200.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,2VSSD@28216|Betaproteobacteria,44WH2@713636|Nitrosomonadales	28216|Betaproteobacteria	T	cheY-homologous receiver domain	pilH	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_4380327_19	580332.Slit_2940	2.482e-62	216.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,2VR2Q@28216|Betaproteobacteria,44WGJ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	cheY-homologous receiver domain	pilG	-	-	ko:K02657	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_4380327_13	580332.Slit_2943	3.211e-107	349.0	COG1225@1|root,COG1225@2|Bacteria,1R9YF@1224|Proteobacteria,2VN9B@28216|Betaproteobacteria,44VDM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
REGS1_k127_4380327_15	580332.Slit_2944	3.338e-103	346.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,2VJS2@28216|Betaproteobacteria,44VQY@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
REGS1_k127_4380327_17	1485544.JQKP01000001_gene1061	7.744e-85	289.0	COG3271@1|root,COG3271@2|Bacteria,1R9YX@1224|Proteobacteria,2VURR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phytochelatin synthase	-	-	-	-	-	-	-	-	-	-	-	-	Phytochelatin
REGS1_k127_4380327_3	402777.KB235904_gene4108	0.0	1062.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG4191@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,COG4191@2|Bacteria,1GBKM@1117|Cyanobacteria,1H7D9@1150|Oscillatoriales	1117|Cyanobacteria	KLT	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,HATPase_c,HisKA,PAS_3,Pkinase,Response_reg
REGS1_k127_4380327_25	580332.Slit_2947	7.405e-29	115.0	COG1942@1|root,COG1942@2|Bacteria,1NC22@1224|Proteobacteria,2VWHU@28216|Betaproteobacteria,44WJF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tautomerase enzyme	-	-	5.3.2.6	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	M00569	R03966,R05389	RC01040,RC01355	ko00000,ko00001,ko00002,ko01000	-	-	-	Tautomerase
REGS1_k127_4380327_18	555778.Hneap_0273	5.697e-64	228.0	COG3667@1|root,COG3667@2|Bacteria,1MXW6@1224|Proteobacteria,1RZEY@1236|Gammaproteobacteria,1X0XC@135613|Chromatiales	135613|Chromatiales	P	Copper resistance protein B precursor (CopB)	-	-	-	ko:K07233	-	-	-	-	ko00000	-	-	-	CopB
REGS1_k127_4380327_7	257310.BB4580	2.134e-233	736.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VH96@28216|Betaproteobacteria,3T2YX@506|Alcaligenaceae	28216|Betaproteobacteria	Q	Multicopper oxidase	copA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
REGS1_k127_4380327_8	580332.Slit_2948	2.934e-228	713.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,1MUUP@1224|Proteobacteria,2VGZC@28216|Betaproteobacteria,44V7Q@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the acetyltransferase family. ArgA subfamily	argA	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
REGS1_k127_4380327_23	580332.Slit_2949	1.336e-42	156.0	COG2924@1|root,COG2924@2|Bacteria,1MZ2V@1224|Proteobacteria,2VTYU@28216|Betaproteobacteria,44W0N@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	yggX	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
REGS1_k127_4380327_2	395494.Galf_2864	0.0	1115.0	COG0855@1|root,COG0855@2|Bacteria,1MUM3@1224|Proteobacteria,2VHH8@28216|Betaproteobacteria,44V8M@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
REGS1_k127_4380327_26	580332.Slit_1564	2.578e-27	115.0	2C9QX@1|root,316K7@2|Bacteria,1PXQK@1224|Proteobacteria,2VWP4@28216|Betaproteobacteria	580332.Slit_1564|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4380327_31	580332.Slit_0049	1.097e-09	59.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,44V7V@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
REGS1_k127_4380327_9	43989.cce_2019	3.238e-216	686.0	COG3593@1|root,COG3593@2|Bacteria,1G8RD@1117|Cyanobacteria,3KJCY@43988|Cyanothece	1117|Cyanobacteria	L	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
REGS1_k127_4380327_28	580332.Slit_2697	4.666e-21	94.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,44V26@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
REGS1_k127_4380327_32	1392540.P256_02187	8.862e-08	59.0	COG3209@1|root,COG3209@2|Bacteria,1RJZY@1224|Proteobacteria,1S166@1236|Gammaproteobacteria,3NMK0@468|Moraxellaceae	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,CHAP
REGS1_k127_4380327_29	883126.HMPREF9710_01231	7.423e-16	89.0	2DR2Z@1|root,339YC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
REGS1_k127_4380327_12	580332.Slit_0121	4.565e-160	507.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
REGS1_k127_4380327_14	580332.Slit_1446	7.877e-107	351.0	COG0492@1|root,COG0492@2|Bacteria,1R12A@1224|Proteobacteria,2WHYF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4472477_2	1123392.AQWL01000001_gene1655	2.84e-57	207.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2W1AG@28216|Betaproteobacteria,1KS01@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
REGS1_k127_4472477_0	1123392.AQWL01000001_gene1654	0.0	1467.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2W1IA@28216|Betaproteobacteria,1KRYS@119069|Hydrogenophilales	119069|Hydrogenophilales	P	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
REGS1_k127_4472477_3	292415.Tbd_1332	1.439e-16	89.0	COG5569@1|root,COG5569@2|Bacteria,1NGSZ@1224|Proteobacteria,2VX21@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Copper binding periplasmic protein CusF	-	-	-	ko:K07810	ko02020,map02020	-	-	-	ko00000,ko00001	2.A.6.1.4	-	-	CusF_Ec
REGS1_k127_4472477_1	395494.Galf_2060	3.889e-134	440.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHI5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
REGS1_k127_4472610_1	580332.Slit_2411	1.991e-59	208.0	COG2927@1|root,COG2927@2|Bacteria,1MZ3V@1224|Proteobacteria,2VTYC@28216|Betaproteobacteria,44VZ8@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DNA polymerase III chi subunit HolC	holC	-	2.7.7.7	ko:K02339	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_chi
REGS1_k127_4472610_0	580332.Slit_2413	0.0	1614.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,2VH5Z@28216|Betaproteobacteria,44V9P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
REGS1_k127_4472610_2	1111732.AZOD01000004_gene977	1.562e-07	57.0	COG4828@1|root,COG4828@2|Bacteria,1RM43@1224|Proteobacteria,1TFHB@1236|Gammaproteobacteria,1X94Y@135614|Xanthomonadales	135614|Xanthomonadales	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
REGS1_k127_4504964_13	1485544.JQKP01000002_gene1451	6.307e-21	92.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VH4I@28216|Betaproteobacteria,44VHM@713636|Nitrosomonadales	28216|Betaproteobacteria	L	UvrD-like helicase C-terminal domain	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_4504964_4	1123487.KB892865_gene1424	1.255e-119	394.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,2VJD9@28216|Betaproteobacteria,2KUGV@206389|Rhodocyclales	206389|Rhodocyclales	C	radical SAM protein	nirJ	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_4504964_10	29581.BW37_04035	1.362e-30	133.0	2DPW6@1|root,333NE@2|Bacteria,1NM0S@1224|Proteobacteria,2W3RD@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4504964_7	1380391.JIAS01000012_gene4519	9.584e-61	217.0	COG1746@1|root,COG1746@2|Bacteria,1RKKB@1224|Proteobacteria	1224|Proteobacteria	J	tRNA cytidylyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
REGS1_k127_4504964_8	1349767.GJA_3583	7.846e-51	183.0	COG0789@1|root,COG0789@2|Bacteria,1RGX6@1224|Proteobacteria,2VSD1@28216|Betaproteobacteria,474HS@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	helix_turn_helix, mercury resistance	cueR	-	-	ko:K19591,ko:K19592	-	M00768,M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind
REGS1_k127_4504964_0	29581.BW37_01716	1.839e-272	856.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,472ZK@75682|Oxalobacteraceae	28216|Betaproteobacteria	P	heavy metal translocating P-type ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
REGS1_k127_4504964_12	349521.HCH_05559	5.258e-28	118.0	COG2867@1|root,COG2867@2|Bacteria,1N9F0@1224|Proteobacteria,1SS9R@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
REGS1_k127_4504964_9	1485544.JQKP01000002_gene1449	1.074e-47	186.0	COG5473@1|root,COG5473@2|Bacteria,1N9UJ@1224|Proteobacteria,2WCG6@28216|Betaproteobacteria,44W0X@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4504964_2	1485544.JQKP01000002_gene1448	1.536e-145	466.0	COG2334@1|root,COG2334@2|Bacteria,1MUKJ@1224|Proteobacteria,2VH2I@28216|Betaproteobacteria,44V2D@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the pseudomonas-type ThrB family	thrB	-	2.7.1.39	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
REGS1_k127_4504964_11	1485544.JQKP01000002_gene1447	4.593e-28	118.0	2C1YJ@1|root,32ZXK@2|Bacteria,1N98H@1224|Proteobacteria,2VVT5@28216|Betaproteobacteria,44VZF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2782)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2782
REGS1_k127_4504964_5	580332.Slit_2989	1.181e-108	359.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,2VIG0@28216|Betaproteobacteria,44V9B@713636|Nitrosomonadales	28216|Betaproteobacteria	K	ParB-like nuclease domain	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
REGS1_k127_4504964_3	1288494.EBAPG3_8040	1.107e-127	412.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2VHNK@28216|Betaproteobacteria,371Z8@32003|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM Cobyrinic acid a,c-diamide synthase	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
REGS1_k127_4504964_6	1485544.JQKP01000012_gene2171	1.68e-77	271.0	COG0357@1|root,COG0357@2|Bacteria,1MY0K@1224|Proteobacteria,2VR3B@28216|Betaproteobacteria,44VPZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
REGS1_k127_4504964_1	1485544.JQKP01000012_gene2172	5.621e-196	616.0	COG0445@1|root,COG0445@2|Bacteria,1MU6F@1224|Proteobacteria,2VIGG@28216|Betaproteobacteria,44V4F@713636|Nitrosomonadales	28216|Betaproteobacteria	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
REGS1_k127_4556393_4	580332.Slit_1532	1.073e-191	600.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,2VI6I@28216|Betaproteobacteria,44V9T@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_4556393_19	62928.azo1626	1.683e-36	139.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,2VTZH@28216|Betaproteobacteria,2KWX1@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_4556393_11	1485544.JQKP01000013_gene1823	3.935e-116	378.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,2VJ3S@28216|Betaproteobacteria,44VP6@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	KR domain	fabG	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_4556393_7	580332.Slit_1529	3.443e-166	531.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,2VJF7@28216|Betaproteobacteria,44V99@713636|Nitrosomonadales	28216|Betaproteobacteria	I	TIGRFAM malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645,ko:K13935,ko:K15355	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
REGS1_k127_4556393_8	1485544.JQKP01000013_gene1825	7.371e-155	494.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2VI2A@28216|Betaproteobacteria,44VNK@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
REGS1_k127_4556393_6	580332.Slit_1527	2.229e-173	550.0	COG0416@1|root,COG0416@2|Bacteria,1MVM3@1224|Proteobacteria,2VI25@28216|Betaproteobacteria,44VJN@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
REGS1_k127_4556393_21	62928.azo1621	7.275e-30	118.0	COG0333@1|root,COG0333@2|Bacteria,1N6RF@1224|Proteobacteria,2VVP5@28216|Betaproteobacteria,2KX6E@206389|Rhodocyclales	206389|Rhodocyclales	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
REGS1_k127_4556393_18	1485544.JQKP01000013_gene1828	4.738e-42	160.0	COG1399@1|root,COG1399@2|Bacteria,1PIWK@1224|Proteobacteria,2W7FZ@28216|Betaproteobacteria,44VYP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
REGS1_k127_4556393_15	1485544.JQKP01000013_gene1829	2.01e-75	263.0	COG0424@1|root,COG0424@2|Bacteria,1RDA9@1224|Proteobacteria,2VQUQ@28216|Betaproteobacteria,44VRW@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Maf-like protein	yceF	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
REGS1_k127_4556393_13	1163617.SCD_n01762	7.505e-93	308.0	COG1926@1|root,COG1926@2|Bacteria,1RAG8@1224|Proteobacteria,2VPNZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
REGS1_k127_4556393_17	580332.Slit_1309	1.677e-46	171.0	COG1846@1|root,COG1846@2|Bacteria,1N78T@1224|Proteobacteria	1224|Proteobacteria	K	Transcription regulator that can specifically activate or repress expression of target genes	slyA	-	-	ko:K06075	-	-	-	-	ko00000,ko03000	-	-	-	MarR,MarR_2
REGS1_k127_4556393_10	580332.Slit_1308	3.977e-144	468.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria	28216|Betaproteobacteria	V	PFAM secretion protein HlyD family protein	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	HlyD_3
REGS1_k127_4556393_1	580332.Slit_1307	1.783e-256	797.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2VJGS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	major facilitator superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
REGS1_k127_4556393_5	580332.Slit_1311	6.516e-183	576.0	COG0709@1|root,COG0709@2|Bacteria,1MWFG@1224|Proteobacteria,2VJSD@28216|Betaproteobacteria,44VM5@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C,Pyr_redox_2
REGS1_k127_4556393_9	580332.Slit_1310	8.967e-150	483.0	COG2603@1|root,COG2603@2|Bacteria,1N4T5@1224|Proteobacteria,2VIMH@28216|Betaproteobacteria,44VMP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Rhodanese Homology Domain	selU	-	-	ko:K06917	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Rhodanese
REGS1_k127_4556393_0	580332.Slit_1305	0.0	1560.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,2VKDZ@28216|Betaproteobacteria,44VIM@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
REGS1_k127_4556393_14	485913.Krac_11550	4.065e-84	284.0	COG1814@1|root,COG1814@2|Bacteria,2G7AE@200795|Chloroflexi	200795|Chloroflexi	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
REGS1_k127_4556393_3	1095769.CAHF01000006_gene1981	1.147e-238	744.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,2VHA5@28216|Betaproteobacteria,472U1@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
REGS1_k127_4556393_22	279714.FuraDRAFT_2026	3.77e-06	49.0	2DFYS@1|root,2ZTSA@2|Bacteria,1P7CE@1224|Proteobacteria,2W6M3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3460)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3460
REGS1_k127_4556393_16	580332.Slit_1434	2.762e-58	213.0	COG3713@1|root,COG3713@2|Bacteria,1PUKA@1224|Proteobacteria,2VT0C@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Outer membrane protein V	-	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
REGS1_k127_4556393_20	1485544.JQKP01000003_gene263	5.565e-31	125.0	COG2919@1|root,COG2919@2|Bacteria,1N7AA@1224|Proteobacteria,2VVQJ@28216|Betaproteobacteria,44W01@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsB	-	-	ko:K05589	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
REGS1_k127_4556393_2	580332.Slit_1884	1.322e-246	764.0	COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,2VH7Y@28216|Betaproteobacteria,44VKW@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
REGS1_k127_4556393_12	395494.Galf_2206	1.847e-113	367.0	COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,2VIQF@28216|Betaproteobacteria,44VM7@713636|Nitrosomonadales	28216|Betaproteobacteria	M	DAHP synthetase I family	kdsA	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
REGS1_k127_457322_25	580332.Slit_0182	1.678e-29	126.0	COG3637@1|root,COG3637@2|Bacteria,1NIE3@1224|Proteobacteria,2VXMU@28216|Betaproteobacteria,44WMS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	OmpA-like transmembrane domain	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA_membrane
REGS1_k127_457322_20	887062.HGR_04818	3.873e-45	171.0	2DMP9@1|root,32SV1@2|Bacteria,1N17Y@1224|Proteobacteria,2VX5P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3015
REGS1_k127_457322_7	887062.HGR_04823	3.079e-174	569.0	28J7E@1|root,2Z92U@2|Bacteria,1NAE1@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
REGS1_k127_457322_16	887062.HGR_04828	3.507e-88	300.0	COG1073@1|root,COG1073@2|Bacteria,1RFAF@1224|Proteobacteria,2WERU@28216|Betaproteobacteria,4AF1F@80864|Comamonadaceae	28216|Betaproteobacteria	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
REGS1_k127_457322_0	580332.Slit_0181	3.089e-308	950.0	COG0043@1|root,COG0043@2|Bacteria,1MU62@1224|Proteobacteria,2VH09@28216|Betaproteobacteria,44VAJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis	ubiD	-	4.1.1.98	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04985,R04986	RC00391	ko00000,ko00001,ko00002,ko01000	-	-	-	UbiD
REGS1_k127_457322_9	580332.Slit_0179	2.407e-146	470.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,2VICZ@28216|Betaproteobacteria,44V9R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241,2.3.1.242	ko:K02517,ko:K12974	ko00540,ko01100,map00540,map01100	M00060	R05146,R10906	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
REGS1_k127_457322_14	580332.Slit_0178	9.799e-108	357.0	COG1560@1|root,COG1560@2|Bacteria,1Q41N@1224|Proteobacteria,2VKN0@28216|Betaproteobacteria,44VQM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB_2	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
REGS1_k127_457322_4	580332.Slit_0177	4.411e-245	758.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,2VH7U@28216|Betaproteobacteria,44VJJ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
REGS1_k127_457322_2	580332.Slit_0176	4.983e-291	896.0	COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2VH57@28216|Betaproteobacteria,44UYB@713636|Nitrosomonadales	28216|Betaproteobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
REGS1_k127_457322_21	395494.Galf_2646	5.026e-45	168.0	COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,2VUY1@28216|Betaproteobacteria,44VVZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Mycobacterial 4 TMS phage holin, superfamily IV	-	-	-	ko:K08972	-	-	-	-	ko00000	-	-	-	Phage_holin_4_2
REGS1_k127_457322_10	1485544.JQKP01000002_gene1591	5.039e-143	457.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,2VHHI@28216|Betaproteobacteria,44VA9@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
REGS1_k127_457322_3	580332.Slit_0173	6.109e-272	842.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,2VH51@28216|Betaproteobacteria,44V3W@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Peptidase family U32 C-terminal domain	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
REGS1_k127_457322_22	1163617.SCD_n00955	2.824e-39	149.0	COG2827@1|root,COG2827@2|Bacteria,1R0EY@1224|Proteobacteria,2VWYM@28216|Betaproteobacteria	28216|Betaproteobacteria	L	GIY-YIG catalytic domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
REGS1_k127_457322_17	580332.Slit_0171	3.879e-79	266.0	COG2731@1|root,COG2731@2|Bacteria,1RJ5F@1224|Proteobacteria,2VTSG@28216|Betaproteobacteria,44VXN@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
REGS1_k127_457322_15	395494.Galf_2649	3.507e-91	302.0	COG3038@1|root,COG3038@2|Bacteria,1RBP8@1224|Proteobacteria,2VQWK@28216|Betaproteobacteria,44W0C@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prokaryotic cytochrome b561	yodB	-	-	ko:K12262	-	-	-	-	ko00000	-	-	-	Ni_hydr_CYTB
REGS1_k127_457322_11	580332.Slit_0170	7.408e-138	451.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	ko:K02690	ko00195,ko01100,map00195,map01100	M00163	-	-	ko00000,ko00001,ko00002,ko00194	-	-	-	DUF1573,OmpA,OmpA_membrane,PsaA_PsaB,TSP_3
REGS1_k127_457322_5	580332.Slit_2926	3.472e-241	752.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VHSB@28216|Betaproteobacteria,44V04@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Nitrogen metabolism transcriptional regulator, NtrC, Fis Family	ntrC	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
REGS1_k127_457322_8	580332.Slit_2925	3.84e-163	519.0	COG3852@1|root,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,2VJN7@28216|Betaproteobacteria,44VKA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART ATP-binding region ATPase domain protein	ntrB	-	2.7.13.3	ko:K07708	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,PAS,PAS_4,PAS_9
REGS1_k127_457322_24	580332.Slit_2924	3.291e-37	145.0	2ADYZ@1|root,313R9@2|Bacteria,1Q78X@1224|Proteobacteria,2WABJ@28216|Betaproteobacteria,44WNK@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
REGS1_k127_457322_1	580332.Slit_2923	2.447e-294	905.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,2VHYE@28216|Betaproteobacteria,44V72@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Glutamine synthetase, catalytic domain	glnA	GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360	5.4.4.3,6.3.1.2	ko:K01915,ko:K20712	ko00220,ko00250,ko00627,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00627,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253,R06988,R09284	RC00010,RC01754,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
REGS1_k127_457322_6	580332.Slit_2922	2.613e-177	563.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,2VJ1J@28216|Betaproteobacteria,44V0Z@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	czcD1	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
REGS1_k127_457322_18	395494.Galf_0049	1.013e-71	244.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VR3P@28216|Betaproteobacteria,44VYE@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_457322_13	159087.Daro_3911	2.204e-117	383.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,2VHSA@28216|Betaproteobacteria,2KV15@206389|Rhodocyclales	206389|Rhodocyclales	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
REGS1_k127_457322_26	580332.Slit_2919	5.698e-17	85.0	COG3313@1|root,COG3313@2|Bacteria,1Q968@1224|Proteobacteria,2WCHA@28216|Betaproteobacteria,44W3E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1289)	-	-	-	ko:K06938	-	-	-	-	ko00000	-	-	-	DUF1289
REGS1_k127_457322_23	1502852.FG94_03115	3.276e-37	141.0	COG0727@1|root,32S46@2|Bacteria,1MZCU@1224|Proteobacteria,2VU00@28216|Betaproteobacteria,474XI@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
REGS1_k127_457322_12	580332.Slit_2917	8.794e-127	410.0	COG3440@1|root,COG3440@2|Bacteria,1N4JP@1224|Proteobacteria,2VVU0@28216|Betaproteobacteria	28216|Betaproteobacteria	V	HNH endonuclease	-	-	-	ko:K07454	-	-	-	-	ko00000	-	-	-	HNH_2
REGS1_k127_457322_19	580332.Slit_2916	1.324e-59	209.0	2BNPG@1|root,32HCH@2|Bacteria,1P81V@1224|Proteobacteria,2W6JN@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4612161_13	504832.OCAR_7386	0.0006215	44.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2TT52@28211|Alphaproteobacteria,3JRVZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
REGS1_k127_4612161_12	395494.Galf_2919	1.16e-11	69.0	2DBQ7@1|root,2ZACT@2|Bacteria,1R7JB@1224|Proteobacteria,2VPP3@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TniQ	-	-	-	-	-	-	-	-	-	-	-	-	TniQ
REGS1_k127_4612161_7	543728.Vapar_5017	1.085e-46	181.0	COG2197@1|root,COG2197@2|Bacteria,1R6Y9@1224|Proteobacteria,2VN8Z@28216|Betaproteobacteria,4AFYN@80864|Comamonadaceae	28216|Betaproteobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE
REGS1_k127_4612161_8	1121918.ARWE01000001_gene479	1.481e-46	183.0	COG1462@1|root,COG1462@2|Bacteria,1Q4KN@1224|Proteobacteria,42U33@68525|delta/epsilon subdivisions,2WQXW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Curli production assembly/transport component CsgG	-	-	-	-	-	-	-	-	-	-	-	-	CsgG
REGS1_k127_4612161_11	378806.STAUR_4953	5.819e-24	118.0	COG1413@1|root,COG1413@2|Bacteria,1P8HR@1224|Proteobacteria	1224|Proteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
REGS1_k127_4612161_0	1485544.JQKP01000013_gene1845	1.122e-301	931.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VHKK@28216|Betaproteobacteria,44VMM@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	proP_2	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
REGS1_k127_4612161_4	1163617.SCD_n00225	5.719e-105	351.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,2VH1X@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,Reg_prop,Y_Y_Y
REGS1_k127_4612161_1	1163617.SCD_n00226	3.958e-135	438.0	COG2172@1|root,COG2172@2|Bacteria,1RD6C@1224|Proteobacteria,2VQE3@28216|Betaproteobacteria	28216|Betaproteobacteria	T	anti-sigma regulatory factor	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE
REGS1_k127_4612161_2	1163617.SCD_n00227	3.965e-114	374.0	COG1366@1|root,COG1366@2|Bacteria,1MVPW@1224|Proteobacteria,2VNVR@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM Sulfate transporter antisigma-factor antagonist STAS	rsbRA	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	Protoglobin,RsbRD_N,STAS
REGS1_k127_4612161_9	1163617.SCD_n00228	1.67e-44	165.0	295X6@1|root,2ZT81@2|Bacteria,1PBJJ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	-
REGS1_k127_4612161_5	335283.Neut_0487	1.934e-92	308.0	COG1272@1|root,COG1272@2|Bacteria,1PGRH@1224|Proteobacteria,2VJR4@28216|Betaproteobacteria,372CA@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Haemolysin-III related	-	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
REGS1_k127_4612161_3	580332.Slit_2371	2.496e-106	353.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,2VNGX@28216|Betaproteobacteria,44VHS@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
REGS1_k127_4612161_6	580332.Slit_2370	2.583e-91	302.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,44VG7@713636|Nitrosomonadales	28216|Betaproteobacteria	D	TIGRFAM cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
REGS1_k127_4622767_4	1485544.JQKP01000020_gene52	2.492e-127	411.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,2VHX4@28216|Betaproteobacteria,44V15@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Polyprenyl synthetase	ispB	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_4622767_2	580332.Slit_0320	3.714e-190	607.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VIPI@28216|Betaproteobacteria,44WDF@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	PFAM major facilitator superfamily MFS_1	proP	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_4622767_6	1485544.JQKP01000004_gene567	6.49e-39	145.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,44W17@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
REGS1_k127_4622767_0	580332.Slit_0343	3.001e-256	799.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,44VIR@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_4622767_3	1472716.KBK24_0104720	3.071e-136	446.0	COG0642@1|root,COG2205@2|Bacteria,1NFHM@1224|Proteobacteria,2WF79@28216|Betaproteobacteria,1KHZA@119060|Burkholderiaceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
REGS1_k127_4622767_5	1123487.KB892863_gene1832	1.236e-100	342.0	COG4566@1|root,COG4566@2|Bacteria,1QVXM@1224|Proteobacteria,2WGZZ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Response regulator receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_4622767_1	1123487.KB892863_gene1833	6.008e-195	616.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,2KUQ7@206389|Rhodocyclales	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_4622767_7	580332.Slit_0343	5.548e-06	51.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,44VIR@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_4628572_3	626418.bglu_2g16070	4.734e-11	63.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VP05@28216|Betaproteobacteria,1K8AN@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_4628572_0	1121035.AUCH01000005_gene1	6.636e-110	364.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria	1224|Proteobacteria	S	PFAM peptidase M28	yfbL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
REGS1_k127_4628572_5	573370.DMR_18940	0.0002447	49.0	2CBA6@1|root,2ZPHF@2|Bacteria,1QE24@1224|Proteobacteria,435US@68525|delta/epsilon subdivisions,2X0A8@28221|Deltaproteobacteria,2MBH3@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4628572_2	595537.Varpa_0478	8.904e-22	97.0	2E6BG@1|root,330Z9@2|Bacteria,1N126@1224|Proteobacteria,2VW8F@28216|Betaproteobacteria,4AG3N@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4705843_15	1112274.KI911560_gene2265	3.749e-10	62.0	COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,2VIG2@28216|Betaproteobacteria,2KKRU@206350|Nitrosomonadales	206350|Nitrosomonadales	O	HflC and HflK could encode or regulate a protease	-	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7,HflK_N
REGS1_k127_4705843_5	395494.Galf_1252	2.166e-127	413.0	COG0330@1|root,COG0330@2|Bacteria,1MV7R@1224|Proteobacteria,2VI9W@28216|Betaproteobacteria,44VKJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	HflC and HflK could regulate a protease	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
REGS1_k127_4705843_13	580332.Slit_1424	1.147e-19	90.0	COG3242@1|root,COG3242@2|Bacteria,1NG9Q@1224|Proteobacteria,2VXNJ@28216|Betaproteobacteria,44WN4@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2065)	-	-	-	ko:K09937	-	-	-	-	ko00000	-	-	-	DUF2065
REGS1_k127_4705843_3	580332.Slit_1425	4.284e-188	595.0	COG3705@1|root,COG3705@2|Bacteria,1MWIG@1224|Proteobacteria,2VHVX@28216|Betaproteobacteria,44V4A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
REGS1_k127_4705843_1	1485544.JQKP01000001_gene1252	1.946e-257	797.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,2VHBR@28216|Betaproteobacteria,44VE3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
REGS1_k127_4705843_14	1121127.JAFA01000021_gene8053	9.89e-19	89.0	COG2944@1|root,COG2944@2|Bacteria,1NHAH@1224|Proteobacteria,2VXNT@28216|Betaproteobacteria,1K7P8@119060|Burkholderiaceae	28216|Betaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_4705843_10	395494.Galf_1448	1.048e-72	254.0	COG2771@1|root,COG2771@2|Bacteria,1N6UR@1224|Proteobacteria,2WGVQ@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K18304	ko02024,ko02025,map02024,map02025	M00644,M00769	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Autoind_bind,GerE
REGS1_k127_4705843_0	1123392.AQWL01000010_gene2291	3.593e-279	867.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ9H@28216|Betaproteobacteria	28216|Betaproteobacteria	U	PFAM ABC-1 domain protein	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
REGS1_k127_4705843_11	1123392.AQWL01000010_gene2292	8.18e-72	249.0	2DN0A@1|root,32UPR@2|Bacteria,1N1BR@1224|Proteobacteria,2VVZG@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4705843_6	580332.Slit_1844	6.006e-108	355.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,44W5F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
REGS1_k127_4705843_12	1123392.AQWL01000007_gene873	3.095e-65	227.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2VKXP@28216|Betaproteobacteria,1KS3P@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
REGS1_k127_4705843_4	522306.CAP2UW1_2627	8.198e-183	576.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_4705843_9	261292.Nit79A3_2564	2.015e-78	270.0	COG1073@1|root,COG1073@2|Bacteria,1RDAY@1224|Proteobacteria,2VQGW@28216|Betaproteobacteria	28216|Betaproteobacteria	S	phosphoribosyltransferase	-	-	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH
REGS1_k127_4705843_2	1131553.JIBI01000007_gene1166	9.466e-195	623.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,2VN8I@28216|Betaproteobacteria,372VF@32003|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM FAD dependent oxidoreductase	glpD	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
REGS1_k127_4705843_7	580332.Slit_2460	5.898e-93	311.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
REGS1_k127_4705843_8	580332.Slit_2461	6.867e-80	273.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,2VN24@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
REGS1_k127_4779728_14	1485544.JQKP01000005_gene365	5.325e-65	226.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,44VB6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_4779728_1	580332.Slit_1418	3.695e-258	800.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,2VI8D@28216|Betaproteobacteria,44V5G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
REGS1_k127_4779728_6	1485544.JQKP01000001_gene1280	3.579e-121	402.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,2VHH5@28216|Betaproteobacteria,44VFV@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamB	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
REGS1_k127_4779728_13	1485544.JQKP01000001_gene1279	6.244e-66	232.0	COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,2VSHE@28216|Betaproteobacteria,44VUI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_21
REGS1_k127_4779728_2	1485544.JQKP01000001_gene1278	8.988e-233	724.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,2VIGA@28216|Betaproteobacteria,44VJ4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM tRNA synthetase class II (G H P and S)	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
REGS1_k127_4779728_3	1485544.JQKP01000001_gene1274	2.929e-224	699.0	COG0821@1|root,COG0821@2|Bacteria,1MUAX@1224|Proteobacteria,2VID7@28216|Betaproteobacteria,44VKE@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
REGS1_k127_4779728_20	395494.Galf_1395	2.825e-39	160.0	COG1426@1|root,COG1426@2|Bacteria,1N240@1224|Proteobacteria,2VVFV@28216|Betaproteobacteria,44VYD@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Helix-turn-helix domain	-	-	-	ko:K15539	-	-	-	-	ko00000	-	-	-	DUF4115,HTH_25
REGS1_k127_4779728_16	395494.Galf_1396	5.507e-61	221.0	COG3063@1|root,COG3063@2|Bacteria,1MXPC@1224|Proteobacteria,2VNC8@28216|Betaproteobacteria,44VS2@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	TIGRFAM type IV pilus biogenesis stability protein PilW	pilF	-	-	ko:K02656	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	TPR_16,TPR_17,TPR_19,TPR_2,TPR_8
REGS1_k127_4779728_4	580332.Slit_1411	6.295e-204	639.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,2VIBN@28216|Betaproteobacteria,44V7I@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
REGS1_k127_4779728_11	580332.Slit_1410	8.11e-73	247.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,44VQP@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
REGS1_k127_4779728_7	1454004.AW11_03136	1.771e-110	372.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,2VP12@28216|Betaproteobacteria,1KPYH@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
REGS1_k127_4779728_5	580332.Slit_1405	1.88e-169	537.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,2VHS0@28216|Betaproteobacteria,44UZD@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
REGS1_k127_4779728_17	1485544.JQKP01000001_gene1325	9.084e-57	204.0	COG3216@1|root,COG3216@2|Bacteria,1RGV6@1224|Proteobacteria,2VSHR@28216|Betaproteobacteria,44VXR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2062)	-	-	-	ko:K09928	-	-	-	-	ko00000	-	-	-	DUF2062
REGS1_k127_4779728_10	1521187.JPIM01000048_gene92	1.579e-74	255.0	COG0225@1|root,COG0225@2|Bacteria,2G6JK@200795|Chloroflexi,375KD@32061|Chloroflexia	32061|Chloroflexia	C	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
REGS1_k127_4779728_0	580332.Slit_1765	0.0	1200.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,2VHFQ@28216|Betaproteobacteria,44VCB@713636|Nitrosomonadales	28216|Betaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
REGS1_k127_4779728_19	1485544.JQKP01000005_gene369	1.418e-51	186.0	COG0346@1|root,COG0346@2|Bacteria,1PVYI@1224|Proteobacteria,2VVCZ@28216|Betaproteobacteria,44VXU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
REGS1_k127_4779728_8	1485544.JQKP01000015_gene2077	2.534e-92	307.0	COG3132@1|root,COG3132@2|Bacteria,1RA13@1224|Proteobacteria,2VQGS@28216|Betaproteobacteria,44WEY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF480	yceH	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480
REGS1_k127_4779728_12	748247.AZKH_4171	4.885e-66	243.0	COG5339@1|root,COG5339@2|Bacteria,1R5PZ@1224|Proteobacteria,2VMEJ@28216|Betaproteobacteria,2KUUE@206389|Rhodocyclales	206389|Rhodocyclales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF945
REGS1_k127_4779728_18	580332.Slit_1261	4.514e-54	192.0	COG2346@1|root,COG2346@2|Bacteria,1RH21@1224|Proteobacteria,2VSUJ@28216|Betaproteobacteria,44VWR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial-like globin	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
REGS1_k127_4779728_9	580332.Slit_1445	2.106e-89	304.0	2CIBN@1|root,2Z8JT@2|Bacteria	2|Bacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
REGS1_k127_4779728_21	1236959.BAMT01000001_gene1040	5.208e-35	139.0	2AJXH@1|root,31AKJ@2|Bacteria,1RJPF@1224|Proteobacteria,2VTF5@28216|Betaproteobacteria,2KMQM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Domain of unknown function (DUF4149)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4149
REGS1_k127_4779728_15	580332.Slit_2830	3.184e-61	215.0	COG2346@1|root,COG2346@2|Bacteria,1NFC6@1224|Proteobacteria	1224|Proteobacteria	S	Bacterial-like globin	-	-	-	-	-	-	-	-	-	-	-	-	Bac_globin
REGS1_k127_484109_14	504832.OCAR_7386	0.0006215	44.0	COG1613@1|root,COG1613@2|Bacteria,1MUAU@1224|Proteobacteria,2TT52@28211|Alphaproteobacteria,3JRVZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	P	Bacterial extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
REGS1_k127_484109_8	314345.SPV1_04128	4.019e-58	218.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
REGS1_k127_484109_0	1485545.JQLW01000005_gene1092	0.0	1277.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria	1224|Proteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K07239,ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1,2.A.6.1.2	-	-	ACR_tran
REGS1_k127_484109_12	314345.SPV1_04118	1.207e-26	112.0	COG0347@1|root,COG0347@2|Bacteria	2|Bacteria	K	Belongs to the P(II) protein family	-	-	-	ko:K04751,ko:K04752	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	-
REGS1_k127_484109_4	652103.Rpdx1_3228	3.5e-88	308.0	2AY7V@1|root,31QA0@2|Bacteria,1RIZH@1224|Proteobacteria,2UQW8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_484109_13	580332.Slit_2542	7.532e-20	93.0	2E8PT@1|root,3330W@2|Bacteria,1N796@1224|Proteobacteria,2VVUA@28216|Betaproteobacteria,44W2D@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_484109_3	338963.Pcar_2308	4.364e-143	456.0	COG0121@1|root,COG0121@2|Bacteria,1MU1J@1224|Proteobacteria,42U7F@68525|delta/epsilon subdivisions,2WR2X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Glutamine amidotransferases class-II	yafJ	-	-	-	-	-	-	-	-	-	-	-	GATase_4
REGS1_k127_484109_10	1242864.D187_009614	1.426e-49	191.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
REGS1_k127_484109_5	903818.KI912268_gene2380	5.985e-67	238.0	COG2885@1|root,COG2885@2|Bacteria,3Y5IQ@57723|Acidobacteria	57723|Acidobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF937,OmpA
REGS1_k127_484109_6	1163617.SCD_n00188	8.939e-66	234.0	COG4089@1|root,COG4089@2|Bacteria,1MV8K@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF1614)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1614
REGS1_k127_484109_9	269799.Gmet_2409	3.178e-53	193.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,42SWA@68525|delta/epsilon subdivisions,2WPE1@28221|Deltaproteobacteria,43W0S@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
REGS1_k127_484109_11	1123393.KB891316_gene1605	5.643e-38	148.0	COG0071@1|root,COG0071@2|Bacteria,1N1RF@1224|Proteobacteria,2VT18@28216|Betaproteobacteria,1KT32@119069|Hydrogenophilales	119069|Hydrogenophilales	O	Hsp20/alpha crystallin family	-	-	-	-	-	-	-	-	-	-	-	-	HSP20
REGS1_k127_484109_2	580332.Slit_0579	2.627e-181	595.0	COG4320@1|root,COG4320@2|Bacteria,1PW3W@1224|Proteobacteria,2WBPK@28216|Betaproteobacteria,44WP2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_484109_1	580332.Slit_0339	7.397e-215	669.0	COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,2VJA4@28216|Betaproteobacteria,44VCK@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
REGS1_k127_484109_7	396588.Tgr7_1317	1.149e-65	231.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,1S3ZJ@1236|Gammaproteobacteria,1X0VZ@135613|Chromatiales	135613|Chromatiales	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
REGS1_k127_4917783_8	580332.Slit_0625	2.783e-91	301.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,2VI59@28216|Betaproteobacteria,44VGH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
REGS1_k127_4917783_7	1485544.JQKP01000011_gene774	5.107e-96	319.0	COG0118@1|root,COG0118@2|Bacteria,1MU4X@1224|Proteobacteria,2VJPI@28216|Betaproteobacteria,44V1Z@713636|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
REGS1_k127_4917783_5	395494.Galf_0436	2.23e-147	468.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2VI38@28216|Betaproteobacteria,44UZI@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Histidine biosynthesis protein	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
REGS1_k127_4917783_4	580332.Slit_0628	1.518e-148	472.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,44VIE@713636|Nitrosomonadales	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
REGS1_k127_4917783_9	580332.Slit_0629	1.322e-67	233.0	COG0139@1|root,COG0139@2|Bacteria,1MW67@1224|Proteobacteria,2VR9B@28216|Betaproteobacteria,44VV6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
REGS1_k127_4917783_11	395494.Galf_0439	1.211e-44	166.0	COG0140@1|root,COG0140@2|Bacteria,1MZEE@1224|Proteobacteria,2VUN8@28216|Betaproteobacteria,44W06@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Phosphoribosyl-ATP pyrophosphohydrolase	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
REGS1_k127_4917783_10	1485544.JQKP01000011_gene769	1.467e-48	176.0	COG0537@1|root,COG0537@2|Bacteria,1RDCJ@1224|Proteobacteria,2VSMS@28216|Betaproteobacteria,44VY0@713636|Nitrosomonadales	28216|Betaproteobacteria	FG	HIT domain	hitA	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	DcpS_C,HIT
REGS1_k127_4917783_14	1123393.KB891329_gene980	1.417e-21	95.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,2VVT6@28216|Betaproteobacteria,1KTFE@119069|Hydrogenophilales	119069|Hydrogenophilales	U	mttA/Hcf106 family	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_4917783_13	1485544.JQKP01000011_gene767	1.803e-27	115.0	COG1826@1|root,COG1826@2|Bacteria,1N73F@1224|Proteobacteria,2VVPX@28216|Betaproteobacteria,44W0W@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation	tatB	-	-	ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
REGS1_k127_4917783_6	395494.Galf_0443	4.683e-97	322.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,2VI2H@28216|Betaproteobacteria,44VAY@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
REGS1_k127_4917783_15	1215092.PA6_018_00010	4.918e-11	65.0	2DBEP@1|root,2Z8SY@2|Bacteria,1N7YS@1224|Proteobacteria,1T0YI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4917783_12	580332.Slit_2776	1.958e-33	131.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,2VVRU@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Belongs to the acylphosphatase family	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
REGS1_k127_4917783_1	1485544.JQKP01000004_gene474	1.874e-244	766.0	COG0659@1|root,COG0659@2|Bacteria,1MVWV@1224|Proteobacteria,2VH45@28216|Betaproteobacteria,44WGN@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Sulfate permease family	sulP	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
REGS1_k127_4917783_0	1485544.JQKP01000004_gene473	0.0	1214.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,2VH19@28216|Betaproteobacteria,44VP7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
REGS1_k127_4917783_3	580332.Slit_2672	6.427e-206	645.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2VIMV@28216|Betaproteobacteria,44V7W@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
REGS1_k127_4917783_2	395494.Galf_0413	4.834e-218	677.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,44VED@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Orn Lys Arg decarboxylase major region	adi	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
REGS1_k127_4937586_1	580332.Slit_1520	4.03e-294	908.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,44VBY@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_4937586_0	395494.Galf_1644	1.815e-294	920.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria	1224|Proteobacteria	C	Formate acetyltransferase	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
REGS1_k127_4961761_0	580332.Slit_1462	0.0	1304.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,44V0B@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
REGS1_k127_4961761_2	580332.Slit_1465	4.134e-279	862.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1MUJM@1224|Proteobacteria,2VH9X@28216|Betaproteobacteria,44VBE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
REGS1_k127_4961761_6	768671.ThimaDRAFT_3524	8.229e-50	181.0	2DZ52@1|root,32V6P@2|Bacteria,1N0M7@1224|Proteobacteria,1SAS5@1236|Gammaproteobacteria,1X0NA@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4961761_1	580332.Slit_1466	0.0	1020.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1MU2A@1224|Proteobacteria,2VHNG@28216|Betaproteobacteria,44V7R@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
REGS1_k127_4961761_4	1485545.JQLW01000012_gene1702	3.51e-57	207.0	COG0500@1|root,COG2226@2|Bacteria,1RB4F@1224|Proteobacteria	1224|Proteobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25,Ubie_methyltran
REGS1_k127_4961761_3	580332.Slit_1017	2.575e-81	274.0	COG0693@1|root,COG0693@2|Bacteria,1N7T2@1224|Proteobacteria,2VS5Q@28216|Betaproteobacteria,44VU8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
REGS1_k127_4961761_5	580332.Slit_1018	4.05e-50	180.0	COG0671@1|root,COG0671@2|Bacteria,1PSM7@1224|Proteobacteria,2WB4I@28216|Betaproteobacteria,44WMP@713636|Nitrosomonadales	28216|Betaproteobacteria	I	SMART phosphoesterase PA-phosphatase related	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
REGS1_k127_4991035_0	580332.Slit_0003	5.655e-316	972.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,44WB9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
REGS1_k127_4991035_2	580332.Slit_0002	2.338e-150	483.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,2VH9B@28216|Betaproteobacteria,44W9E@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
REGS1_k127_4991035_1	580332.Slit_0001	1.036e-207	655.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,2VHH0@28216|Betaproteobacteria,44W93@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
REGS1_k127_4991035_3	580332.Slit_2962	9.912e-116	379.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,2VHI1@28216|Betaproteobacteria,44V8U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
REGS1_k127_4991035_4	580332.Slit_2963	9.696e-95	324.0	COG3107@1|root,COG3107@2|Bacteria,1MUHR@1224|Proteobacteria,2VSUT@28216|Betaproteobacteria,44W8F@713636|Nitrosomonadales	28216|Betaproteobacteria	M	LppC putative lipoprotein	-	-	-	ko:K07121	-	-	-	-	ko00000	-	-	-	LppC
REGS1_k127_4991035_7	1485544.JQKP01000002_gene1658	2.288e-37	151.0	COG0792@1|root,COG0792@2|Bacteria,1N6VN@1224|Proteobacteria,2VU20@28216|Betaproteobacteria,44VYK@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
REGS1_k127_4991035_5	580332.Slit_2965	7.948e-88	293.0	COG0279@1|root,COG0279@2|Bacteria,1NJ8X@1224|Proteobacteria,2VN12@28216|Betaproteobacteria,44VMZ@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
REGS1_k127_4991035_8	228410.NE1008	6.914e-32	133.0	COG2823@1|root,COG2823@2|Bacteria,1MUZ2@1224|Proteobacteria,2VQIS@28216|Betaproteobacteria,37337@32003|Nitrosomonadales	28216|Betaproteobacteria	S	transport-associated	-	-	-	-	-	-	-	-	-	-	-	-	BON
REGS1_k127_4991035_6	1485544.JQKP01000002_gene1661	9.431e-75	253.0	COG0615@1|root,COG0615@2|Bacteria,1REW3@1224|Proteobacteria,2VR6S@28216|Betaproteobacteria,44VQT@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	aut	-	2.7.7.70	ko:K21345	ko00540,ko01100,map00540,map01100	M00064	R05644	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_4991035_9	682795.AciX8_0750	1.12e-15	88.0	29833@1|root,2ZV92@2|Bacteria,3Y940@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4991035_10	211165.AJLN01000104_gene6585	1.341e-15	83.0	2DXAJ@1|root,3444N@2|Bacteria,1GFV2@1117|Cyanobacteria	1117|Cyanobacteria	S	Immunity protein 42	-	-	-	-	-	-	-	-	-	-	-	-	Imm42
REGS1_k127_4991035_12	1137799.GZ78_22140	0.0008264	43.0	2DF3Y@1|root,2ZQDY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4991035_11	1120968.AUBX01000014_gene2337	1.167e-09	65.0	2EBYQ@1|root,335Y0@2|Bacteria,4NVN8@976|Bacteroidetes,47X01@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_4998980_2	580332.Slit_1450	2.631e-157	497.0	COG1830@1|root,COG1830@2|Bacteria,1MW9N@1224|Proteobacteria,2VPZ0@28216|Betaproteobacteria,44W77@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
REGS1_k127_4998980_5	266264.Rmet_2950	2.399e-105	353.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1R6XF@1224|Proteobacteria,2VHK6@28216|Betaproteobacteria,1K0ZK@119060|Burkholderiaceae	28216|Betaproteobacteria	T	response regulator	phcR	-	-	ko:K19622	ko02020,map02020	-	-	-	ko00000,ko00001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_4998980_3	1005048.CFU_0153	9.544e-132	428.0	COG2201@1|root,COG2201@2|Bacteria,1QUZP@1224|Proteobacteria,2WGN6@28216|Betaproteobacteria,476NH@75682|Oxalobacteraceae	28216|Betaproteobacteria	NT	Response regulator receiver domain	jqsR	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_4998980_4	580332.Slit_0964	3.294e-129	419.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,2VHYK@28216|Betaproteobacteria,44VQH@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_4998980_0	666681.M301_0675	0.0	2081.0	COG2373@1|root,COG2373@2|Bacteria,1MV7J@1224|Proteobacteria,2VI2R@28216|Betaproteobacteria,2KNBM@206350|Nitrosomonadales	206350|Nitrosomonadales	S	Alpha-2-Macroglobulin	-	-	-	ko:K06894	-	-	-	-	ko00000	-	-	-	A2M,A2M_N,A2M_N_2,MG1
REGS1_k127_4998980_1	666681.M301_0674	3.907e-275	867.0	COG4953@1|root,COG4953@2|Bacteria,1MUA9@1224|Proteobacteria,2VMGW@28216|Betaproteobacteria,2KMZG@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Penicillin-Binding Protein C-terminus Family	-	-	2.4.1.129	ko:K05367	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	BiPBP_C,Transgly,Transpeptidase
REGS1_k127_5010170_2	580332.Slit_1204	9.482e-318	977.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VHES@28216|Betaproteobacteria,44VKR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter	yjjK	-	3.6.3.25	ko:K06020	-	-	-	-	ko00000,ko01000	-	-	-	ABC_tran,ABC_tran_Xtn
REGS1_k127_5010170_8	395494.Galf_2614	2.1e-68	236.0	COG2193@1|root,COG2193@2|Bacteria	2|Bacteria	P	ferroxidase activity	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
REGS1_k127_5010170_6	580332.Slit_1879	9.695e-126	404.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VKFG@28216|Betaproteobacteria,44VP1@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
REGS1_k127_5010170_11	671143.DAMO_0437	1.745e-47	177.0	2EBKA@1|root,335KQ@2|Bacteria,2NRDT@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5010170_1	580332.Slit_1881	0.0	1070.0	COG0514@1|root,COG0514@2|Bacteria,1MVGG@1224|Proteobacteria,2VH8W@28216|Betaproteobacteria,44VG6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DEAD DEAH box helicase domain protein	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
REGS1_k127_5010170_12	580332.Slit_2030	1.618e-36	140.0	COG1993@1|root,COG1993@2|Bacteria,1RH30@1224|Proteobacteria,2WFX5@28216|Betaproteobacteria,44W30@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized ACR, COG1993	-	-	-	-	-	-	-	-	-	-	-	-	DUF190
REGS1_k127_5010170_10	1485544.JQKP01000019_gene24	1.421e-64	222.0	COG0239@1|root,COG0239@2|Bacteria,1MZNH@1224|Proteobacteria,2VUBZ@28216|Betaproteobacteria,44VTA@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
REGS1_k127_5010170_3	1216976.AX27061_4353	3.105e-301	945.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VKIW@28216|Betaproteobacteria,3T1CY@506|Alcaligenaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenases	fadE	-	-	ko:K06445	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01175,R01279,R03777,R03857,R03990,R04751,R04754	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,DUF1974
REGS1_k127_5010170_5	580332.Slit_1860	1.173e-134	433.0	COG1028@1|root,COG1028@2|Bacteria,1MUSQ@1224|Proteobacteria,2VM6G@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K13775	ko00281,map00281	-	R08087,R08096,R10125,R10126	RC00080,RC00087	ko00000,ko00001	-	-	-	adh_short
REGS1_k127_5010170_4	1485544.JQKP01000004_gene510	2.064e-145	469.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,44V2C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
REGS1_k127_5010170_7	580332.Slit_1859	1.33e-90	302.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,2VI0U@28216|Betaproteobacteria,44V2C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
REGS1_k127_5010170_9	580332.Slit_1858	3.595e-65	224.0	COG1607@1|root,COG1607@2|Bacteria,1MZAZ@1224|Proteobacteria,2VR9M@28216|Betaproteobacteria,44WG2@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM thioesterase superfamily protein	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
REGS1_k127_5010170_0	580332.Slit_1856	0.0	1090.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,2VHS7@28216|Betaproteobacteria,44V1M@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Enoyl-CoA hydratase/isomerase	fadN	-	1.1.1.35	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	M00087	R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
REGS1_k127_5029450_3	580332.Slit_1265	3.524e-17	81.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,44V5X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
REGS1_k127_5029450_2	580332.Slit_1266	1.118e-51	184.0	COG0718@1|root,COG0718@2|Bacteria,1RGZD@1224|Proteobacteria,2VSJ2@28216|Betaproteobacteria,44VXA@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
REGS1_k127_5029450_0	580332.Slit_1267	1.117e-110	362.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,2VJVJ@28216|Betaproteobacteria,44VGC@713636|Nitrosomonadales	28216|Betaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
REGS1_k127_5029450_1	580332.Slit_1268	4.288e-91	302.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,2VITB@28216|Betaproteobacteria,44V60@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_5043132_8	580332.Slit_2237	2.584e-34	134.0	COG0702@1|root,COG0702@2|Bacteria,1MW44@1224|Proteobacteria,2VM5Q@28216|Betaproteobacteria,44WCW@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	NmrA-like family	-	-	1.6.5.2	ko:K19267	ko00130,ko01110,map00130,map01110	-	R02964,R03643,R03816	RC00819	ko00000,ko00001,ko01000	-	-	-	NAD_binding_10,NmrA
REGS1_k127_5043132_6	1485544.JQKP01000001_gene1015	1.276e-58	207.0	COG1733@1|root,COG1733@2|Bacteria,1MZ6N@1224|Proteobacteria,2VSXJ@28216|Betaproteobacteria,44WH4@713636|Nitrosomonadales	28216|Betaproteobacteria	K	HxlR-like helix-turn-helix	ytfH	-	-	-	-	-	-	-	-	-	-	-	HxlR
REGS1_k127_5043132_3	580332.Slit_2239	1.217e-133	430.0	COG0560@1|root,COG0560@2|Bacteria,1MWA3@1224|Proteobacteria,2VKZJ@28216|Betaproteobacteria,44UYY@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Haloacid dehalogenase domain protein hydrolase	serB	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	DUF4072,HAD
REGS1_k127_5043132_7	580332.Slit_2240	9.306e-47	175.0	2DE4Z@1|root,2ZKI5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Gal_Lectin
REGS1_k127_5043132_10	211165.AJLN01000120_gene795	5.32e-05	49.0	COG0727@1|root,COG0727@2|Bacteria,1GFCE@1117|Cyanobacteria	1117|Cyanobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
REGS1_k127_5043132_5	580332.Slit_1523	7.802e-71	242.0	COG1734@1|root,COG1734@2|Bacteria,1RD08@1224|Proteobacteria,2VQR5@28216|Betaproteobacteria,44VXB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
REGS1_k127_5043132_4	1144319.PMI16_00348	8.244e-85	289.0	COG1806@1|root,COG1806@2|Bacteria,1MUHU@1224|Proteobacteria,2VI4R@28216|Betaproteobacteria,472KF@75682|Oxalobacteraceae	28216|Betaproteobacteria	F	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation	ydiA	-	2.7.11.33,2.7.4.28	ko:K09773	-	-	-	-	ko00000,ko01000	-	-	-	Kinase-PPPase
REGS1_k127_5043132_0	323848.Nmul_A0998	0.0	1165.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,2VHQ3@28216|Betaproteobacteria,372G3@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
REGS1_k127_5043132_1	580332.Slit_1487	1.352e-180	577.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,2VHU4@28216|Betaproteobacteria,44V23@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
REGS1_k127_5043132_2	580332.Slit_1488	1.078e-155	501.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,44V0M@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
REGS1_k127_5043132_9	340177.Cag_1123	9.298e-27	113.0	COG1943@1|root,COG1943@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
REGS1_k127_5055423_4	1230476.C207_03286	2.609e-09	59.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,3JR8N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,Methyltransf_23,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
REGS1_k127_5055423_2	1096546.WYO_1302	9.452e-17	85.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2TRVB@28211|Alphaproteobacteria,1JSAA@119045|Methylobacteriaceae	28211|Alphaproteobacteria	O	PFAM TPR repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
REGS1_k127_5055423_0	580332.Slit_0539	2.777e-198	632.0	COG0457@1|root,COG0457@2|Bacteria,1NFQW@1224|Proteobacteria,2VQUC@28216|Betaproteobacteria,44WD9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_8
REGS1_k127_5055423_1	580332.Slit_0538	1.805e-33	136.0	COG4969@1|root,COG4969@2|Bacteria,1N7EQ@1224|Proteobacteria,2VVSJ@28216|Betaproteobacteria,44W47@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Prokaryotic N-terminal methylation motif	pilA	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
REGS1_k127_5067661_0	360910.BAV0422	4.202e-229	722.0	28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,2VU8A@28216|Betaproteobacteria,3T6RG@506|Alcaligenaceae	28216|Betaproteobacteria	S	Bacteriophage head to tail connecting protein	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
REGS1_k127_5067661_6	1367847.JCM7686_2182	1.791e-06	54.0	2EK5N@1|root,33DW2@2|Bacteria,1NHDG@1224|Proteobacteria,2UJBG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5067661_3	218493.SBG_0890	1.207e-26	119.0	2EMSH@1|root,33FEX@2|Bacteria,1NKIE@1224|Proteobacteria,1SGT4@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5067661_2	218493.SBG_0889	8.813e-39	155.0	2EBBJ@1|root,335C8@2|Bacteria,1NE1C@1224|Proteobacteria,1SF45@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF3037)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3037
REGS1_k127_5067661_5	614083.AWQR01000035_gene3622	7.413e-13	77.0	COG5581@1|root,COG5581@2|Bacteria	2|Bacteria	M	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
REGS1_k127_5067661_7	402626.Rpic_1828	3.431e-05	55.0	2E0UY@1|root,32WCA@2|Bacteria,1N62C@1224|Proteobacteria,2VWKQ@28216|Betaproteobacteria,1KB2P@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5067661_1	82995.CR62_16655	2.166e-161	524.0	COG0507@1|root,COG0507@2|Bacteria,1R1AT@1224|Proteobacteria,1RS66@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Participates in initiation and elongation during chromosome replication	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5137498_11	580332.Slit_2198	4.32e-23	104.0	COG0666@1|root,COG2114@1|root,COG0666@2|Bacteria,COG2114@2|Bacteria,1NAJG@1224|Proteobacteria,2VJW8@28216|Betaproteobacteria,44WHA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Guanylate_cyc
REGS1_k127_5137498_0	580332.Slit_2241	0.0	1363.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VH3Q@28216|Betaproteobacteria,44WDB@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_lgC,Ribonuc_red_lgN
REGS1_k127_5137498_3	1163617.SCD_n00218	1.06e-141	457.0	COG0676@1|root,COG0676@2|Bacteria,1Q7VN@1224|Proteobacteria,2VKZK@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glucose-6-phosphate 1-epimerase family	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
REGS1_k127_5137498_8	395494.Galf_0101	1.926e-67	241.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_5137498_1	580332.Slit_0515	1.143e-199	627.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,2VH0J@28216|Betaproteobacteria,44VJD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
REGS1_k127_5137498_6	580332.Slit_0514	3.138e-91	305.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,2VJ98@28216|Betaproteobacteria,44V24@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
REGS1_k127_5137498_7	580332.Slit_0512	5.988e-89	295.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,2VQ3U@28216|Betaproteobacteria,44VRQ@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
REGS1_k127_5137498_2	580332.Slit_0511	1.651e-143	459.0	COG0217@1|root,COG0217@2|Bacteria,1MW3X@1224|Proteobacteria,2VIA5@28216|Betaproteobacteria,44VFD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
REGS1_k127_5137498_13	580332.Slit_1429	8.23e-12	67.0	2DGZJ@1|root,2ZXVD@2|Bacteria,1PA8Z@1224|Proteobacteria,2W5F6@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5137498_10	748247.AZKH_1551	4.953e-47	172.0	COG1403@1|root,COG1403@2|Bacteria,1RGZQ@1224|Proteobacteria,2VSZE@28216|Betaproteobacteria,2KWRE@206389|Rhodocyclales	206389|Rhodocyclales	L	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
REGS1_k127_5137498_4	580332.Slit_0878	3.005e-110	361.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria	1224|Proteobacteria	S	beta-lactamase domain protein	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
REGS1_k127_5137498_5	580332.Slit_1246	2.988e-95	314.0	COG4681@1|root,COG4681@2|Bacteria,1RDR9@1224|Proteobacteria,2VR81@28216|Betaproteobacteria,44VRH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	YaeQ	yaeQ	-	-	-	-	-	-	-	-	-	-	-	YaeQ
REGS1_k127_5137498_9	580332.Slit_2317	2.465e-58	207.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,2VSE7@28216|Betaproteobacteria,44VZB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM Class I peptide chain release factor	yaeJ	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
REGS1_k127_5137498_12	580332.Slit_2318	6.715e-17	80.0	COG2501@1|root,COG2501@2|Bacteria,1N7NW@1224|Proteobacteria,2VVQY@28216|Betaproteobacteria,44W1T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	S4 domain	ybcJ	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
REGS1_k127_5167144_18	580332.Slit_1868	3.089e-49	176.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VKX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
REGS1_k127_5167144_20	232721.Ajs_3983	1.391e-40	156.0	2E4NM@1|root,32ZHG@2|Bacteria,1NBCY@1224|Proteobacteria,2VYD7@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5167144_4	580332.Slit_0314	8.493e-181	574.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_5167144_23	1288494.EBAPG3_12200	5.503e-30	124.0	COG2010@1|root,COG2010@2|Bacteria,1NF1C@1224|Proteobacteria,2VVP1@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5167144_7	580332.Slit_2300	1.053e-96	319.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,2VS2C@28216|Betaproteobacteria,44VHF@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM Peptidase S24 S26A S26B, conserved region	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	Peptidase_S24
REGS1_k127_5167144_1	580332.Slit_1743	1.257e-243	759.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,2VIKN@28216|Betaproteobacteria,44VPB@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
REGS1_k127_5167144_15	580332.Slit_1744	1.998e-57	205.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,2VR40@28216|Betaproteobacteria,44VTS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L9, N-terminal domain	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
REGS1_k127_5167144_19	1485544.JQKP01000017_gene632	4.083e-42	156.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,2VTWT@28216|Betaproteobacteria,44VYS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
REGS1_k127_5167144_24	580332.Slit_1746	2.82e-29	119.0	COG2965@1|root,COG2965@2|Bacteria,1PXB0@1224|Proteobacteria,2WCSV@28216|Betaproteobacteria,44WM5@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA replication, synthesis of RNA primer	-	-	-	ko:K02686	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
REGS1_k127_5167144_13	580332.Slit_1747	5.797e-64	220.0	COG0360@1|root,COG0360@2|Bacteria,1RH82@1224|Proteobacteria,2VR79@28216|Betaproteobacteria,44VTR@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
REGS1_k127_5167144_3	1095769.CAHF01000013_gene3378	3.218e-195	618.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria,473TS@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
REGS1_k127_5167144_5	1123393.KB891316_gene1249	1.068e-150	481.0	COG2199@1|root,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,2VJCR@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS,PAS_9
REGS1_k127_5167144_14	358220.C380_15305	2.193e-63	234.0	COG2199@1|root,COG2199@2|Bacteria,1RGCV@1224|Proteobacteria,2WHJC@28216|Betaproteobacteria,4AJYD@80864|Comamonadaceae	28216|Betaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_5167144_11	1121035.AUCH01000003_gene1219	1.546e-79	297.0	COG0642@1|root,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,2KUH6@206389|Rhodocyclales	206389|Rhodocyclales	T	Histidine kinase	-	-	2.7.13.3	ko:K20975	ko02020,ko02025,map02020,map02025	M00820	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_5167144_31	395494.Galf_1960	4.793e-20	106.0	COG4251@1|root,COG4251@2|Bacteria,1NSQ1@1224|Proteobacteria,2VJX9@28216|Betaproteobacteria,44W8B@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY
REGS1_k127_5167144_17	1122164.JHWF01000019_gene482	1.18e-49	180.0	COG3437@1|root,COG3437@2|Bacteria,1QXI4@1224|Proteobacteria	1224|Proteobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_5167144_12	28072.Nos7524_1496	5.569e-72	258.0	COG4251@1|root,COG4251@2|Bacteria,1GHC4@1117|Cyanobacteria,1HK8D@1161|Nostocales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_2,PHY
REGS1_k127_5167144_6	395494.Galf_2172	6.278e-100	329.0	COG0500@1|root,COG0500@2|Bacteria,1REJ2@1224|Proteobacteria,2VQ90@28216|Betaproteobacteria,44W5P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
REGS1_k127_5167144_30	497964.CfE428DRAFT_5116	2.316e-20	93.0	2942H@1|root,2ZRH9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5167144_8	580332.Slit_1317	6.732e-90	300.0	COG1853@1|root,COG1853@2|Bacteria,1NB1B@1224|Proteobacteria,2VQ0V@28216|Betaproteobacteria,44WMG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
REGS1_k127_5167144_25	1282362.AEAC466_13530	2.222e-28	120.0	COG3108@1|root,COG3108@2|Bacteria,1N1HE@1224|Proteobacteria,2UFZF@28211|Alphaproteobacteria,2KJ7Q@204458|Caulobacterales	204458|Caulobacterales	S	Peptidase M15A	-	-	-	ko:K03791	-	-	-	-	ko00000	-	GH19	-	Peptidase_M15_3
REGS1_k127_5167144_36	1304872.JAGC01000005_gene1633	7.15e-06	56.0	COG2110@1|root,COG2110@2|Bacteria,1R14Y@1224|Proteobacteria	1224|Proteobacteria	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5167144_16	56780.SYN_02283	3.7e-51	203.0	COG4675@1|root,COG4675@2|Bacteria,1N2XN@1224|Proteobacteria	1224|Proteobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5167144_37	504832.OCAR_6140	5.948e-05	56.0	28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2793
REGS1_k127_5167144_27	557598.LHK_01555	6.099e-28	130.0	COG5301@1|root,COG5301@2|Bacteria	2|Bacteria	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2793,Phage_fiber_2
REGS1_k127_5167144_22	279714.FuraDRAFT_0294	2.383e-34	138.0	COG4675@1|root,COG4675@2|Bacteria,1N2XN@1224|Proteobacteria	1224|Proteobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5167144_34	375286.mma_2192	4.368e-10	72.0	2ES6Y@1|root,33JRQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5167144_35	504832.OCAR_6140	6.335e-07	62.0	28JTG@1|root,2Z9IR@2|Bacteria,1R0GC@1224|Proteobacteria,2TURR@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF2793)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2793
REGS1_k127_5167144_26	557598.LHK_01555	5.571e-28	129.0	COG5301@1|root,COG5301@2|Bacteria	2|Bacteria	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF2793,Phage_fiber_2
REGS1_k127_5167144_28	1485544.JQKP01000004_gene550	2.77e-22	101.0	2E3UK@1|root,32YRY@2|Bacteria,1PSPV@1224|Proteobacteria,2WAA7@28216|Betaproteobacteria,44W36@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3106)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
REGS1_k127_5167144_9	580332.Slit_2405	2.746e-82	280.0	COG1595@1|root,COG1595@2|Bacteria,1R9WC@1224|Proteobacteria,2VQ28@28216|Betaproteobacteria,44VVF@713636|Nitrosomonadales	28216|Betaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	sigE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_5167144_0	580332.Slit_2404	0.0	999.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,2VJ55@28216|Betaproteobacteria,44V6P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM thiamine pyrophosphate	ilvI	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
REGS1_k127_5167144_10	580332.Slit_2403	1.278e-80	271.0	COG0440@1|root,COG0440@2|Bacteria,1RAGN@1224|Proteobacteria,2VH1H@28216|Betaproteobacteria,44VPP@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	ilvH	GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
REGS1_k127_5167144_2	1485544.JQKP01000004_gene545	5.463e-203	633.0	COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,2VIQ5@28216|Betaproteobacteria,44V1V@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
REGS1_k127_5191729_5	1198452.Jab_1c02620	3.527e-17	85.0	COG0810@1|root,COG0810@2|Bacteria,1MZQW@1224|Proteobacteria,2VU0N@28216|Betaproteobacteria,474MU@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Chalcone isomerase-like	-	-	-	-	-	-	-	-	-	-	-	-	Chalcone_3
REGS1_k127_5191729_1	580332.Slit_1850	2.071e-227	707.0	COG0183@1|root,COG0183@2|Bacteria,1MU5G@1224|Proteobacteria,2VIF8@28216|Betaproteobacteria,44VHW@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Thiolase, C-terminal domain	fadA	-	2.3.1.16	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	M00087,M00113	R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000	-	-	-	Thiolase_C,Thiolase_N
REGS1_k127_5191729_2	85643.Tmz1t_2793	3.83e-62	218.0	COG0315@1|root,COG0315@2|Bacteria,1RCYZ@1224|Proteobacteria,2VR7B@28216|Betaproteobacteria,2KW2Z@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
REGS1_k127_5191729_4	640081.Dsui_2154	1.609e-55	200.0	COG0314@1|root,COG0314@2|Bacteria,1RGUX@1224|Proteobacteria,2VRMG@28216|Betaproteobacteria,2KW54@206389|Rhodocyclales	206389|Rhodocyclales	H	Molybdopterin converting factor, large subunit	moaE	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
REGS1_k127_5191729_6	391165.GbCGDNIH1_2086	9.955e-13	72.0	COG1977@1|root,COG1977@2|Bacteria,1N0IE@1224|Proteobacteria,2UF4F@28211|Alphaproteobacteria,2JTYV@204441|Rhodospirillales	204441|Rhodospirillales	H	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin	moaD	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
REGS1_k127_5191729_3	85643.Tmz1t_2526	5.182e-60	212.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,2KWDE@206389|Rhodocyclales	206389|Rhodocyclales	H	molybdopterin-guanine dinucleotide biosynthesis protein	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
REGS1_k127_5191729_0	580332.Slit_1672	5.242e-237	739.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,2VICS@28216|Betaproteobacteria,44V38@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	cysG	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302,ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M,TP_methylase
REGS1_k127_5215080_30	1485544.JQKP01000004_gene502	2.751e-29	118.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,2VH4G@28216|Betaproteobacteria,44VHI@713636|Nitrosomonadales	28216|Betaproteobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
REGS1_k127_5215080_10	580332.Slit_1067	3.506e-163	519.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,44V16@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_5215080_13	580332.Slit_1068	4.014e-110	362.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,44V2M@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
REGS1_k127_5215080_33	580332.Slit_1069	2.461e-28	117.0	COG1314@1|root,COG1314@2|Bacteria,1N8MF@1224|Proteobacteria,2VU0P@28216|Betaproteobacteria,44W05@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
REGS1_k127_5215080_22	582744.Msip34_0671	7.624e-61	211.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,2VSI3@28216|Betaproteobacteria,2KMRP@206350|Nitrosomonadales	206350|Nitrosomonadales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
REGS1_k127_5215080_14	580332.Slit_1071	2.595e-99	325.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,2VIWK@28216|Betaproteobacteria,44VDZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
REGS1_k127_5215080_18	580332.Slit_1072	1.503e-82	279.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,2VHHV@28216|Betaproteobacteria,44VSK@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
REGS1_k127_5215080_4	580332.Slit_1073	7.627e-264	814.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,2VHEC@28216|Betaproteobacteria,44V6Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
REGS1_k127_5215080_20	1485544.JQKP01000010_gene806	5.016e-77	259.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,2VQD9@28216|Betaproteobacteria,44VSP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
REGS1_k127_5215080_2	1485544.JQKP01000010_gene807	2.55e-273	841.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,44VM8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_5215080_0	580332.Slit_1076	0.0	1169.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,2VJYV@28216|Betaproteobacteria,44UZF@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
REGS1_k127_5215080_9	580332.Slit_1077	4.87e-190	599.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,2VHD0@28216|Betaproteobacteria,44V52@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
REGS1_k127_5215080_15	580332.Slit_1078	3.042e-89	296.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2VIQP@28216|Betaproteobacteria,44V2Y@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
REGS1_k127_5215080_19	580332.Slit_1079	1.94e-79	270.0	COG0839@1|root,COG0839@2|Bacteria,1MWJV@1224|Proteobacteria,2VJ4G@28216|Betaproteobacteria,44VQ4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
REGS1_k127_5215080_28	264198.Reut_A0971	1.035e-39	152.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2VSDV@28216|Betaproteobacteria,1K8CG@119060|Burkholderiaceae	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
REGS1_k127_5215080_1	580332.Slit_1081	0.0	1076.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,2VJ2J@28216|Betaproteobacteria,44V2B@713636|Nitrosomonadales	28216|Betaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
REGS1_k127_5215080_3	1485544.JQKP01000010_gene814	1.571e-271	841.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2VIAX@28216|Betaproteobacteria,44VBV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
REGS1_k127_5215080_7	580332.Slit_1083	6.291e-233	728.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,2VHWX@28216|Betaproteobacteria,44VEU@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
REGS1_k127_5215080_16	1485544.JQKP01000010_gene816	7.028e-85	284.0	COG0494@1|root,COG0494@2|Bacteria,1RCX7@1224|Proteobacteria,2VRU5@28216|Betaproteobacteria,44VPW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	NUDIX domain	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
REGS1_k127_5215080_5	580332.Slit_1085	1.548e-241	748.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VI9I@28216|Betaproteobacteria,44V4J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ammonium Transporter Family	-	-	-	ko:K03320,ko:K06580	-	-	-	-	ko00000,ko02000,ko04090	1.A.11,1.A.11.4	-	-	Ammonium_transp
REGS1_k127_5215080_25	666681.M301_0483	6.892e-51	194.0	COG4191@1|root,COG4585@1|root,COG4191@2|Bacteria,COG4585@2|Bacteria,1N1PW@1224|Proteobacteria,2VU49@28216|Betaproteobacteria	28216|Betaproteobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
REGS1_k127_5215080_21	1485544.JQKP01000001_gene954	5.118e-67	231.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,2VR66@28216|Betaproteobacteria,44WGP@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Type II secretion system (T2SS), protein G	gspG2	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_5215080_12	580332.Slit_1831	3.992e-137	447.0	COG1459@1|root,COG1459@2|Bacteria,1N8FA@1224|Proteobacteria,2VJ0W@28216|Betaproteobacteria,44WAF@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02455	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSF
REGS1_k127_5215080_6	1485544.JQKP01000001_gene953	1.127e-238	753.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,44W5G@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_5215080_24	1485544.JQKP01000001_gene952	1.628e-53	200.0	2BGQG@1|root,32APG@2|Bacteria,1PXFZ@1224|Proteobacteria,2WCW7@28216|Betaproteobacteria,44WJ8@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5215080_32	666681.M301_0463	5.189e-29	122.0	2E3Q5@1|root,32YN4@2|Bacteria,1NA23@1224|Proteobacteria,2VYHM@28216|Betaproteobacteria,2KNBQ@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PilN
REGS1_k127_5215080_29	1485544.JQKP01000001_gene950	4.34e-37	150.0	COG3167@1|root,COG3167@2|Bacteria,1N0IK@1224|Proteobacteria,2VXJE@28216|Betaproteobacteria,44WKP@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	carbon utilization	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5215080_34	1123020.AUIE01000003_gene724	2.162e-18	93.0	2E5FR@1|root,3307F@2|Bacteria,1N89J@1224|Proteobacteria,1TC3A@1236|Gammaproteobacteria,1YJRW@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5215080_8	666681.M301_0466	7.321e-228	729.0	COG0457@1|root,COG4796@1|root,COG0457@2|Bacteria,COG4796@2|Bacteria,1QUY7@1224|Proteobacteria,2VJ8Z@28216|Betaproteobacteria,2KKT1@206350|Nitrosomonadales	28216|Betaproteobacteria	U	type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	STN,Secretin,Secretin_N
REGS1_k127_5215080_23	1123368.AUIS01000016_gene2545	9.168e-58	205.0	COG4968@1|root,COG4968@2|Bacteria,1QVCD@1224|Proteobacteria,1T58B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
REGS1_k127_5215080_27	1095769.CAHF01000022_gene430	1.122e-47	174.0	COG2165@1|root,COG2165@2|Bacteria,1N1QJ@1224|Proteobacteria,2VTYJ@28216|Betaproteobacteria,474VB@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	prepilin-type N-terminal cleavage methylation	gspG4	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
REGS1_k127_5215080_26	1485544.JQKP01000001_gene945	1.719e-49	183.0	COG2165@1|root,COG2165@2|Bacteria,1MZ5I@1224|Proteobacteria,2VU7P@28216|Betaproteobacteria,44WII@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type II secretory pathway, pseudopilin	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5215080_17	580332.Slit_1821	6.277e-83	281.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRBV@28216|Betaproteobacteria	28216|Betaproteobacteria	T	response regulator	-	-	-	ko:K14979	ko02020,map02020	M00663	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
REGS1_k127_5215080_11	314345.SPV1_05153	2.164e-161	530.0	COG2197@1|root,COG2203@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria	1224|Proteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HD,HD_5,PAS,PAS_4,PAS_9,Response_reg
REGS1_k127_5215080_35	658612.MD26_08180	0.0002073	50.0	COG3175@1|root,COG3175@2|Bacteria,1RDTU@1224|Proteobacteria,1S5XA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	oxidase, assembly	ctaG	-	-	ko:K02258	ko00190,ko01100,ko04714,map00190,map01100,map04714	M00154	-	-	ko00000,ko00001,ko00002,ko03029	3.D.4.8	-	-	CtaG_Cox11
REGS1_k127_5215080_31	643867.Ftrac_2777	2.876e-29	132.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	2.7.11.1	ko:K02450,ko:K12132	-	M00331	-	-	ko00000,ko00002,ko01000,ko01001,ko02044	9.B.42	-	-	CHAP,DUF1302,Glucosaminidase,Pkinase,SH3_3,SH3_5,SLH
REGS1_k127_5302092_1	580332.Slit_2321	1.941e-235	758.0	COG3829@1|root,COG5001@1|root,COG5002@1|root,COG3829@2|Bacteria,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44WCD@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_9,Phosphonate-bd
REGS1_k127_5302092_13	497965.Cyan7822_0442	4.046e-34	144.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,3KGBC@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
REGS1_k127_5302092_17	1502770.JQMG01000001_gene2057	1.974e-09	59.0	2DT3B@1|root,33IHT@2|Bacteria,1NK4F@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5302092_9	395494.Galf_0149	5.717e-72	253.0	COG3437@1|root,COG3437@2|Bacteria,1RJ22@1224|Proteobacteria,2VSV3@28216|Betaproteobacteria,44VV8@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
REGS1_k127_5302092_5	580332.Slit_2416	6.846e-144	468.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_5302092_10	395494.Galf_0149	9.654e-60	209.0	COG3437@1|root,COG3437@2|Bacteria,1RJ22@1224|Proteobacteria,2VSV3@28216|Betaproteobacteria,44VV8@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	PFAM metal-dependent phosphohydrolase HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
REGS1_k127_5302092_18	338969.Rfer_2293	3.651e-09	59.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,2VH1F@28216|Betaproteobacteria,4ABIR@80864|Comamonadaceae	28216|Betaproteobacteria	KT	PFAM Metal-dependent phosphohydrolase, HD	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	HD,HD_5,Response_reg
REGS1_k127_5302092_14	1485544.JQKP01000003_gene232	2.473e-25	107.0	COG1722@1|root,COG1722@2|Bacteria,1PTYP@1224|Proteobacteria,2VVQV@28216|Betaproteobacteria,44W3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
REGS1_k127_5302092_3	580332.Slit_0705	1.574e-145	470.0	COG0142@1|root,COG0142@2|Bacteria,1MWNG@1224|Proteobacteria,2VHQV@28216|Betaproteobacteria,44V0J@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Polyprenyl synthetase	ispA	-	2.5.1.1,2.5.1.10	ko:K00795	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364	R01658,R02003	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
REGS1_k127_5302092_0	580332.Slit_0706	0.0	1004.0	COG1154@1|root,COG1154@2|Bacteria,1MUSJ@1224|Proteobacteria,2VHXG@28216|Betaproteobacteria,44VC0@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
REGS1_k127_5302092_4	1485544.JQKP01000003_gene229	3.266e-144	461.0	COG1469@1|root,COG1469@2|Bacteria,1MV1B@1224|Proteobacteria,2VIC9@28216|Betaproteobacteria,44V3J@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Type I GTP cyclohydrolase folE2	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
REGS1_k127_5302092_6	1485544.JQKP01000015_gene2068	2.831e-108	355.0	COG0518@1|root,COG0518@2|Bacteria,1MUDH@1224|Proteobacteria,2VJEI@28216|Betaproteobacteria,44V94@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
REGS1_k127_5302092_12	580332.Slit_2372	5.496e-39	151.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_5302092_15	1356852.N008_16320	2.024e-23	100.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,47TTT@768503|Cytophagia	976|Bacteroidetes	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
REGS1_k127_5302092_7	118173.KB235914_gene1212	6.001e-96	320.0	COG4106@1|root,COG4106@2|Bacteria,1G3BF@1117|Cyanobacteria,1H9QD@1150|Oscillatoriales	1117|Cyanobacteria	S	Methyltransferase domain	-	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
REGS1_k127_5302092_11	1121405.dsmv_3194	8.055e-57	201.0	COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,42RNC@68525|delta/epsilon subdivisions,2WP7G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
REGS1_k127_5302092_8	1485544.JQKP01000003_gene83	1.272e-92	311.0	COG0625@1|root,COG0625@2|Bacteria,1RHSK@1224|Proteobacteria,2VIJ5@28216|Betaproteobacteria,44V67@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Glutathione S-transferase, C-terminal domain	yibF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_2,GST_N_3
REGS1_k127_5302092_2	580332.Slit_0526	4.253e-205	644.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,44UZH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
REGS1_k127_5410146_7	580332.Slit_1597	4.938e-64	221.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,44VIB@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC family	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
REGS1_k127_5410146_15	1116472.MGMO_20c00300	3.76e-06	54.0	2D00F@1|root,32T7G@2|Bacteria,1N5VT@1224|Proteobacteria,1S9HD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5410146_4	748247.AZKH_4071	1.311e-96	323.0	28I9W@1|root,2Z8CH@2|Bacteria,1QCN6@1224|Proteobacteria,2VM9W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
REGS1_k127_5410146_12	316056.RPC_4466	1.452e-26	110.0	COG5554@1|root,COG5554@2|Bacteria,1N7DQ@1224|Proteobacteria,2UF73@28211|Alphaproteobacteria,3K06X@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	NifT/FixU protein	fixU	-	-	ko:K02593	-	-	-	-	ko00000	-	-	-	NifT
REGS1_k127_5410146_13	114615.BRADO5413	8.691e-26	114.0	2D4GA@1|root,32TH1@2|Bacteria,1N4D6@1224|Proteobacteria,2U7ZG@28211|Alphaproteobacteria,3JZM6@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
REGS1_k127_5410146_11	187303.BN69_2645	1.492e-28	118.0	2BW7G@1|root,330EE@2|Bacteria,1NBXB@1224|Proteobacteria,2UBQH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PFAM NifZ family protein	-	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
REGS1_k127_5410146_9	316056.RPC_4468	6.373e-37	142.0	COG5554@1|root,COG5554@2|Bacteria,1N1CF@1224|Proteobacteria,2U941@28211|Alphaproteobacteria,3JZU7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	NifZ domain	nifZ	-	-	ko:K02597	-	-	-	-	ko00000	-	-	-	NifZ
REGS1_k127_5410146_5	1121033.AUCF01000003_gene3064	7.14e-76	262.0	COG1413@1|root,COG1413@2|Bacteria,1N94K@1224|Proteobacteria,2U34H@28211|Alphaproteobacteria,2JSKS@204441|Rhodospirillales	204441|Rhodospirillales	C	LRV protein FeS4 cluster	-	-	-	-	-	-	-	-	-	-	-	-	LRV,LRV_FeS
REGS1_k127_5410146_8	748247.AZKH_4062	6.14e-43	160.0	COG0316@1|root,COG0316@2|Bacteria,1N011@1224|Proteobacteria,2VUD1@28216|Betaproteobacteria,2KZ6X@206389|Rhodocyclales	206389|Rhodocyclales	S	Iron-sulphur cluster biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	Fe-S_biosyn
REGS1_k127_5410146_10	748247.AZKH_4061	1.779e-35	135.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VVW7@28216|Betaproteobacteria,2KZ5B@206389|Rhodocyclales	206389|Rhodocyclales	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
REGS1_k127_5410146_0	1538295.JY96_18750	1.604e-273	848.0	COG0535@1|root,COG0535@2|Bacteria,1MWDC@1224|Proteobacteria,2VJBQ@28216|Betaproteobacteria,1KK9D@119065|unclassified Burkholderiales	28216|Betaproteobacteria	C	Nitrogenase cofactor biosynthesis protein NifB	nifB	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
REGS1_k127_5410146_3	572477.Alvin_0883	2.093e-127	420.0	COG2200@1|root,COG2200@2|Bacteria,1PDZY@1224|Proteobacteria,1RZPI@1236|Gammaproteobacteria,1WY2U@135613|Chromatiales	135613|Chromatiales	T	PFAM EAL domain protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL
REGS1_k127_5410146_2	243159.AFE_1527	1.145e-186	598.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,1T1G7@1236|Gammaproteobacteria,2NCXI@225057|Acidithiobacillales	225057|Acidithiobacillales	KT	Nif-specific regulatory protein	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
REGS1_k127_5410146_1	582744.Msip34_1848	2.308e-215	677.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,2VH91@28216|Betaproteobacteria,2KM7T@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
REGS1_k127_5410146_6	59538.XP_005974537.1	8.24e-66	227.0	COG0822@1|root,KOG3361@2759|Eukaryota,3A1JG@33154|Opisthokonta,3BPFS@33208|Metazoa,3D6D7@33213|Bilateria,48E6G@7711|Chordata,4959C@7742|Vertebrata,3JC7V@40674|Mammalia,4IYDR@91561|Cetartiodactyla	33208|Metazoa	C	Iron-sulfur cluster assembly enzyme	-	-	-	ko:K22068	-	-	-	-	ko00000,ko03029	-	-	-	Fe-S_biosyn,NifU_N
REGS1_k127_5410146_14	556269.ACDQ01000001_gene1209	1.643e-13	72.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,2VR2M@28216|Betaproteobacteria,474AD@75682|Oxalobacteraceae	28216|Betaproteobacteria	C	Required for insertion of 4Fe-4S clusters	erpA	-	-	ko:K15724	-	-	-	-	ko00000	-	-	-	Fe-S_biosyn
REGS1_k127_5416336_3	580332.Slit_1364	7.247e-139	448.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,2VHPG@28216|Betaproteobacteria,44UYT@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
REGS1_k127_5416336_5	1485544.JQKP01000001_gene1260	4.714e-51	186.0	COG0848@1|root,COG0848@2|Bacteria,1N0ZA@1224|Proteobacteria,2VUF4@28216|Betaproteobacteria,44VVS@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
REGS1_k127_5416336_4	395494.Galf_0662	2.928e-82	279.0	COG0811@1|root,COG0811@2|Bacteria,1QNJ1@1224|Proteobacteria,2VITY@28216|Betaproteobacteria,44V9Z@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	exbB2	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
REGS1_k127_5416336_2	580332.Slit_1367	1.89e-187	595.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,2VJIC@28216|Betaproteobacteria,44VD3@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
REGS1_k127_5416336_0	580332.Slit_1368	5.225e-231	729.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,2VMHK@28216|Betaproteobacteria,44V80@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
REGS1_k127_5416336_6	580332.Slit_1369	2.569e-50	186.0	COG2076@1|root,COG2076@2|Bacteria,1NAUF@1224|Proteobacteria,2WE9Q@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Small Multidrug Resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	EamA,Multi_Drug_Res
REGS1_k127_5416336_1	580332.Slit_1370	7.617e-212	661.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,2VJDZ@28216|Betaproteobacteria,44VGP@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
REGS1_k127_5483915_9	626418.bglu_2g16070	1.602e-10	61.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VP05@28216|Betaproteobacteria,1K8AN@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_5483915_3	398578.Daci_5445	5.494e-77	270.0	COG1073@1|root,COG1073@2|Bacteria,1RCY0@1224|Proteobacteria,2VR4Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
REGS1_k127_5483915_6	1205753.A989_13794	6.024e-51	190.0	2BZXI@1|root,32R5Z@2|Bacteria,1RKAP@1224|Proteobacteria,1RTDQ@1236|Gammaproteobacteria,1XAZN@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5483915_5	1485544.JQKP01000007_gene2012	1.205e-55	198.0	COG3431@1|root,COG3431@2|Bacteria,1P1M5@1224|Proteobacteria,2W87U@28216|Betaproteobacteria,44WHD@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphate-starvation-inducible E	-	-	-	-	-	-	-	-	-	-	-	-	PsiE
REGS1_k127_5483915_2	580332.Slit_2528	1.772e-99	331.0	28KE4@1|root,2ZA0D@2|Bacteria,1MXZT@1224|Proteobacteria,2VNI6@28216|Betaproteobacteria,44W5V@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5483915_1	580332.Slit_2529	5.656e-116	382.0	COG0672@1|root,COG0672@2|Bacteria,1MX1M@1224|Proteobacteria,2VHEE@28216|Betaproteobacteria,44WAH@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM iron permease FTR1	-	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	FTR1
REGS1_k127_5483915_7	395494.Galf_0863	3.683e-34	135.0	COG4633@1|root,COG4633@2|Bacteria,1N6VB@1224|Proteobacteria,2WHPH@28216|Betaproteobacteria,44WHV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
REGS1_k127_5483915_4	580332.Slit_2531	5.586e-70	239.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,2VR52@28216|Betaproteobacteria,44WFD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	PFAM ferric-uptake regulator	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
REGS1_k127_5483915_10	365046.Rta_31920	0.0004405	51.0	2CHMN@1|root,340GB@2|Bacteria,1NZBK@1224|Proteobacteria,2W3BS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5483915_8	1134912.AJTV01000018_gene3285	5.321e-16	84.0	2B3D3@1|root,31W1V@2|Bacteria,1MYTY@1224|Proteobacteria,2U6J7@28211|Alphaproteobacteria,370CY@31993|Methylocystaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5483915_0	580332.Slit_1492	2.226e-195	619.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2VIM4@28216|Betaproteobacteria,44VII@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH,HHH_2,HHH_5,UVR,UvrC_HhH_N
REGS1_k127_5509878_0	1366050.N234_11530	4.203e-109	368.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,1MXEY@1224|Proteobacteria,2VIJ2@28216|Betaproteobacteria	1224|Proteobacteria	C	cytochrome c oxidase cbb3-type, subunit II	-	-	-	ko:K00405	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,FixO
REGS1_k127_5509878_3	1458357.BG58_01855	6.389e-16	89.0	COG1276@1|root,COG1276@2|Bacteria,1RCZ0@1224|Proteobacteria,2W1TV@28216|Betaproteobacteria,1JZNG@119060|Burkholderiaceae	28216|Betaproteobacteria	P	PFAM copper resistance D domain protein	-	-	-	ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	CopD
REGS1_k127_5509878_5	640510.BC1001_2954	1.112e-11	74.0	COG2372@1|root,COG2372@2|Bacteria,1N8SS@1224|Proteobacteria,2VXMG@28216|Betaproteobacteria,1K9G3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Copper resistance protein	-	-	-	ko:K07156	-	-	-	-	ko00000,ko02000	9.B.62.2	-	-	CopC
REGS1_k127_5509878_1	580332.Slit_2284	3.906e-75	259.0	COG1047@1|root,COG1047@2|Bacteria,1RD35@1224|Proteobacteria,2VQA2@28216|Betaproteobacteria,44VUC@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Peptidyl-prolyl cis-trans isomerase	slyD	-	5.2.1.8	ko:K03775	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_5509878_2	580332.Slit_2285	6.466e-69	237.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VRCR@28216|Betaproteobacteria,44WEK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Bacterial protein of unknown function (DUF899)	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_5509878_4	580332.Slit_2286	8.91e-15	84.0	COG2850@1|root,COG2850@2|Bacteria,1MW30@1224|Proteobacteria,2VH3D@28216|Betaproteobacteria,44V9M@713636|Nitrosomonadales	28216|Betaproteobacteria	S	A domain family that is part of the cupin metalloenzyme superfamily.	ycfD	-	1.14.11.47	ko:K18850	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Cupin_4
REGS1_k127_5529167_7	1429851.X548_18010	1.584e-11	69.0	2F8BX@1|root,340QY@2|Bacteria,1NZ1P@1224|Proteobacteria,1SI9F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	yjeN	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5529167_2	395494.Galf_2654	2.054e-142	456.0	COG0382@1|root,COG0382@2|Bacteria,1MV4Q@1224|Proteobacteria,2VHEU@28216|Betaproteobacteria,44VQ9@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
REGS1_k127_5529167_0	580332.Slit_0311	0.0	1045.0	COG1200@1|root,COG1200@2|Bacteria,1MWN2@1224|Proteobacteria,2VHE8@28216|Betaproteobacteria,44V3B@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
REGS1_k127_5529167_6	580332.Slit_0313	8.797e-60	209.0	COG0251@1|root,COG0251@2|Bacteria,1MZ3J@1224|Proteobacteria,2VRQ3@28216|Betaproteobacteria,44VX5@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
REGS1_k127_5529167_3	1163617.SCD_n02290	5.81e-140	467.0	COG3437@1|root,COG3829@1|root,COG4191@1|root,COG5001@1|root,COG3437@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS_3,PAS_9,Response_reg
REGS1_k127_5529167_1	1485544.JQKP01000007_gene1964	4.676e-225	704.0	COG0477@1|root,COG2814@2|Bacteria,1MVSH@1224|Proteobacteria,2VITN@28216|Betaproteobacteria,44V0W@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	yajR	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
REGS1_k127_5529167_4	580332.Slit_0800	8.585e-77	259.0	COG0629@1|root,COG0629@2|Bacteria,1RCWT@1224|Proteobacteria,2VR2Z@28216|Betaproteobacteria,44VVD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
REGS1_k127_5529167_5	396588.Tgr7_1499	1.867e-71	256.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria,1WVV9@135613|Chromatiales	135613|Chromatiales	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF
REGS1_k127_5606790_5	1485544.JQKP01000004_gene506	6.3e-93	306.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,2VH4A@28216|Betaproteobacteria,44VJK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
REGS1_k127_5606790_2	580332.Slit_2076	1.055e-164	528.0	COG4394@1|root,COG4394@2|Bacteria,1MYVF@1224|Proteobacteria,2VHIB@28216|Betaproteobacteria,44V84@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2331
REGS1_k127_5606790_1	580332.Slit_2077	5.606e-191	602.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VKXU@28216|Betaproteobacteria,44UZP@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_5606790_0	580332.Slit_2078	1.581e-215	674.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2VIIH@28216|Betaproteobacteria,44V5Z@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_5606790_3	395494.Galf_2065	7.376e-112	364.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VJBY@28216|Betaproteobacteria,44VNJ@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_5606790_4	1163617.SCD_n02307	5.164e-105	357.0	COG0642@1|root,COG2205@2|Bacteria,1N1Z2@1224|Proteobacteria,2WGRW@28216|Betaproteobacteria	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	2.7.13.3	ko:K07649	ko02020,map02020	M00457	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	2CSK_N,HATPase_c,HisKA
REGS1_k127_5693530_0	1485544.JQKP01000010_gene837	0.0	1107.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,2VHHJ@28216|Betaproteobacteria,44VEJ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
REGS1_k127_5693530_1	580332.Slit_1490	4.21e-194	612.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,2W3RM@28216|Betaproteobacteria,44VN6@713636|Nitrosomonadales	28216|Betaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
REGS1_k127_5693530_2	580332.Slit_1489	3.97e-130	419.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2VKEW@28216|Betaproteobacteria,44VQ5@713636|Nitrosomonadales	28216|Betaproteobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_5763007_19	580332.Slit_0534	1.811e-38	145.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,2VH0D@28216|Betaproteobacteria,44W4T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART beta-lactamase domain protein	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
REGS1_k127_5763007_2	580332.Slit_0533	8.751e-292	913.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	cyaA	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_5763007_7	580332.Slit_0532	1.269e-100	334.0	COG1716@1|root,COG1716@2|Bacteria,1MW1M@1224|Proteobacteria,2VJ1K@28216|Betaproteobacteria,44WCZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
REGS1_k127_5763007_4	580332.Slit_0531	9.316e-124	402.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,2VM6F@28216|Betaproteobacteria,44W64@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART protein phosphatase 2C domain protein	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
REGS1_k127_5763007_0	580332.Slit_0530	0.0	1211.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
REGS1_k127_5763007_9	580332.Slit_1985	1.812e-89	299.0	COG2761@1|root,COG2761@2|Bacteria,1NXUB@1224|Proteobacteria,2VNUN@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	DSBA Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
REGS1_k127_5763007_3	1485544.JQKP01000003_gene260	1.81e-165	534.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44V4Y@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
REGS1_k127_5763007_10	1123514.KB905899_gene1173	2.001e-76	271.0	COG3437@1|root,COG3437@2|Bacteria,1MUB8@1224|Proteobacteria,1RPH3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_5
REGS1_k127_5763007_21	580332.Slit_1989	1.183e-15	81.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,44VYG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
REGS1_k127_5763007_18	251229.Chro_5034	2.791e-42	171.0	COG0666@1|root,COG0666@2|Bacteria,1G0E1@1117|Cyanobacteria,3VHP9@52604|Pleurocapsales	1117|Cyanobacteria	S	PFAM Ankyrin repeat	ank	-	-	ko:K06867	-	-	-	-	ko00000	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5
REGS1_k127_5763007_12	580332.Slit_0389	2.573e-69	241.0	COG1656@1|root,COG1656@2|Bacteria	2|Bacteria	F	Mut7-C RNAse domain	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
REGS1_k127_5763007_20	498211.CJA_1010	5.285e-31	126.0	COG3296@1|root,COG3296@2|Bacteria,1RET3@1224|Proteobacteria,1S4H0@1236|Gammaproteobacteria,1FHSF@10|Cellvibrio	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
REGS1_k127_5763007_16	580332.Slit_1607	2.249e-50	188.0	COG3118@1|root,COG3118@2|Bacteria,1MV0R@1224|Proteobacteria,2VI6Z@28216|Betaproteobacteria,44WIX@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thioredoxin	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_19,TPR_20,Thioredoxin
REGS1_k127_5763007_6	580332.Slit_1666	6.12e-109	370.0	COG2203@1|root,COG4191@1|root,COG5001@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HAMP,PAS,PAS_4,PAS_9,SBP_bac_3
REGS1_k127_5763007_11	580332.Slit_1319	1.522e-74	252.0	COG1671@1|root,COG1671@2|Bacteria,1RCZA@1224|Proteobacteria,2VRAZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Belongs to the UPF0178 family	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
REGS1_k127_5763007_22	338963.Pcar_2266	1.573e-13	74.0	COG4461@1|root,COG4461@2|Bacteria,1NGDW@1224|Proteobacteria,42XBQ@68525|delta/epsilon subdivisions,2WSTR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1176,LprI
REGS1_k127_5763007_8	580332.Slit_1872	3.935e-93	308.0	COG3548@1|root,COG3548@2|Bacteria,1PGBQ@1224|Proteobacteria,2W8V4@28216|Betaproteobacteria,44WNB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1211)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1211
REGS1_k127_5763007_1	580332.Slit_1315	0.0	1062.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,2VH0V@28216|Betaproteobacteria,44VAI@713636|Nitrosomonadales	28216|Betaproteobacteria	L	HELICc2	dinG	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
REGS1_k127_5763007_24	1120999.JONM01000019_gene3435	5.034e-13	71.0	COG1943@1|root,COG1943@2|Bacteria,1RCWW@1224|Proteobacteria,2VSPX@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
REGS1_k127_5763007_25	349521.HCH_00821	3.095e-12	73.0	2EH8A@1|root,33B04@2|Bacteria,1NXJT@1224|Proteobacteria,1SPRU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5763007_17	272134.KB731324_gene5961	1.361e-47	177.0	COG3324@1|root,COG3324@2|Bacteria,1G6S0@1117|Cyanobacteria,1HG10@1150|Oscillatoriales	1117|Cyanobacteria	S	Glyoxalase-like domain	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
REGS1_k127_5763007_15	522306.CAP2UW1_0034	1.518e-52	196.0	COG0860@1|root,COG0860@2|Bacteria,1RJBG@1224|Proteobacteria,2VS51@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Cell wall hydrolase autolysin	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
REGS1_k127_5763007_23	7668.SPU_015269-tr	3.332e-13	78.0	COG0666@1|root,KOG4369@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,KOG4369@2759|Eukaryota,38BVK@33154|Opisthokonta,3BAXI@33208|Metazoa,3D42P@33213|Bilateria	33208|Metazoa	M	Ankyrin repeats (many copies)	-	-	-	ko:K10380,ko:K15502,ko:K15503	ko04624,ko05205,map04624,map05205	-	-	-	ko00000,ko00001,ko01009,ko03400,ko04812	-	-	-	Ank_2,Ank_3,Ank_4,Ank_5,ZU5
REGS1_k127_5763007_13	56110.Oscil6304_3156	2.485e-62	244.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G0BI@1117|Cyanobacteria,1H9XU@1150|Oscillatoriales	1117|Cyanobacteria	S	Soluble NSF attachment protein, SNAP	-	-	-	-	-	-	-	-	-	-	-	-	CHAT,TPR_12,TPR_7,TPR_8
REGS1_k127_5763007_5	580332.Slit_1739	3.011e-121	410.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MWHK@1224|Proteobacteria	1224|Proteobacteria	T	Adenylate cyclase	cyaG2	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,NTP_transf_9
REGS1_k127_5792904_4	580332.Slit_0950	1.6e-135	434.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,2VHZ0@28216|Betaproteobacteria,44V0C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
REGS1_k127_5792904_8	580332.Slit_0949	2.785e-91	306.0	COG1428@1|root,COG1428@2|Bacteria,1RC50@1224|Proteobacteria,2VQ8U@28216|Betaproteobacteria,44W91@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Deoxynucleoside kinase	dgk	-	-	-	-	-	-	-	-	-	-	-	dNK
REGS1_k127_5792904_12	1485544.JQKP01000019_gene14	3.826e-73	249.0	COG0801@1|root,COG0801@2|Bacteria,1MZH8@1224|Proteobacteria,2VSE2@28216|Betaproteobacteria,44VXI@713636|Nitrosomonadales	28216|Betaproteobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
REGS1_k127_5792904_0	580332.Slit_0947	1.805e-224	702.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,2VHY5@28216|Betaproteobacteria,44VAR@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
REGS1_k127_5792904_13	580332.Slit_2301	5.673e-67	234.0	2DMT2@1|root,32TGY@2|Bacteria,1R3E1@1224|Proteobacteria,2VUA9@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5792904_21	596154.Alide2_4797	6.671e-18	90.0	COG3577@1|root,COG3577@2|Bacteria,1N2PE@1224|Proteobacteria,2VTH4@28216|Betaproteobacteria,4AF4K@80864|Comamonadaceae	28216|Betaproteobacteria	S	gag-polyprotein putative aspartyl protease	-	-	-	ko:K06985	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	Asp_protease_2,gag-asp_proteas
REGS1_k127_5792904_6	1485544.JQKP01000019_gene9	2.149e-109	357.0	COG0560@1|root,COG0560@2|Bacteria,1RA1A@1224|Proteobacteria,2VMGV@28216|Betaproteobacteria,44VMB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490	-	-	-	-	-	-	-	-	-	-	-	-	HAD
REGS1_k127_5792904_15	580332.Slit_0945	2.425e-57	206.0	COG4625@1|root,COG4625@2|Bacteria,1N0QY@1224|Proteobacteria,2VS48@28216|Betaproteobacteria	28216|Betaproteobacteria	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5792904_11	580332.Slit_0944	1.062e-84	295.0	COG0593@1|root,COG0593@2|Bacteria,1MVW6@1224|Proteobacteria,2VSFD@28216|Betaproteobacteria,44VQF@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Bacterial dnaA  protein	hda	-	-	ko:K10763	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA
REGS1_k127_5792904_7	395494.Galf_0603	5.043e-109	363.0	COG0628@1|root,COG0628@2|Bacteria,1MW0B@1224|Proteobacteria,2VHDW@28216|Betaproteobacteria,44WDZ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	AI-2E family transporter	perM	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_5792904_2	1485544.JQKP01000019_gene5	8.445e-182	576.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,2VHJT@28216|Betaproteobacteria,44VG1@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM AIR synthase related protein domain protein	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
REGS1_k127_5792904_9	580332.Slit_0942	3.166e-91	308.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,2VJG8@28216|Betaproteobacteria,44VND@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
REGS1_k127_5792904_14	1485544.JQKP01000003_gene154	1.145e-60	216.0	COG3147@1|root,COG3147@2|Bacteria,1R129@1224|Proteobacteria,2WHYD@28216|Betaproteobacteria,44VVT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
REGS1_k127_5792904_19	1163617.SCD_n02359	1.502e-26	122.0	COG3170@1|root,COG3170@2|Bacteria,1MWZB@1224|Proteobacteria,2VNBQ@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
REGS1_k127_5792904_1	580332.Slit_0939	1.545e-201	638.0	COG0144@1|root,COG0144@2|Bacteria,1MV2Q@1224|Proteobacteria,2VI1D@28216|Betaproteobacteria,44VJF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	rsmB_2	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N
REGS1_k127_5792904_3	1198452.Jab_1c07210	6.906e-143	460.0	COG3739@1|root,COG3739@2|Bacteria,1PMEC@1224|Proteobacteria,2VJYG@28216|Betaproteobacteria,473UG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF817)	-	-	-	-	-	-	-	-	-	-	-	-	DUF817
REGS1_k127_5792904_18	580332.Slit_0699	3.964e-27	110.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,2VVW8@28216|Betaproteobacteria,44W27@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
REGS1_k127_5792904_17	580332.Slit_0698	5.286e-43	157.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,2VU1B@28216|Betaproteobacteria,44W1P@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
REGS1_k127_5792904_16	426114.THI_0284	2.872e-46	171.0	COG1846@1|root,COG1846@2|Bacteria,1PC0C@1224|Proteobacteria,2VUH3@28216|Betaproteobacteria	28216|Betaproteobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
REGS1_k127_5792904_20	1173025.GEI7407_3749	9.201e-26	109.0	COG3369@1|root,COG3369@2|Bacteria,1G7ZE@1117|Cyanobacteria,1HCSP@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Iron-binding zinc finger CDGSH type	-	-	-	-	-	-	-	-	-	-	-	-	zf-CDGSH
REGS1_k127_5792904_5	1485544.JQKP01000004_gene453	5.129e-110	369.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,2VKTW@28216|Betaproteobacteria,44VW9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	RadC-like JAB domain	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
REGS1_k127_5792904_10	580332.Slit_0751	1.892e-87	295.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,2VI4X@28216|Betaproteobacteria,44V6U@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
REGS1_k127_5846429_10	580332.Slit_1265	3.134e-96	316.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,2VIE0@28216|Betaproteobacteria,44V5X@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5
REGS1_k127_5846429_18	1123392.AQWL01000004_gene2785	1.143e-33	136.0	COG3637@1|root,COG3637@2|Bacteria,1PWS4@1224|Proteobacteria,2WAG8@28216|Betaproteobacteria,1KTGR@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Lipid A 3-O-deacylase (PagL)	-	-	-	-	-	-	-	-	-	-	-	-	PagL
REGS1_k127_5846429_19	1163617.SCD_n02094	4.061e-31	125.0	COG4095@1|root,COG4095@2|Bacteria,1N759@1224|Proteobacteria,2VVPU@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PQ loop repeat	-	-	-	ko:K15383	-	-	-	-	ko00000,ko02000	9.A.58.2	-	-	PQ-loop
REGS1_k127_5846429_20	318464.IO99_04170	3.206e-11	72.0	COG0406@1|root,COG0406@2|Bacteria,1VEMM@1239|Firmicutes,24GJW@186801|Clostridia,36KFN@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the phosphoglycerate mutase family	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
REGS1_k127_5846429_3	580332.Slit_1260	6.96e-143	457.0	COG2518@1|root,COG2518@2|Bacteria,1NMMQ@1224|Proteobacteria,2VH3B@28216|Betaproteobacteria,44VBR@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
REGS1_k127_5846429_16	580332.Slit_1186	1.927e-60	212.0	COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,2VTBD@28216|Betaproteobacteria,44WHB@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5846429_23	1171373.PACID_17260	6.08e-05	53.0	COG3324@1|root,COG3324@2|Bacteria,2IRXF@201174|Actinobacteria	201174|Actinobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
REGS1_k127_5846429_22	406124.ACPC01000014_gene818	4.095e-09	65.0	291YW@1|root,2ZPID@2|Bacteria,1V3V6@1239|Firmicutes,4HGYJ@91061|Bacilli,1ZG6E@1386|Bacillus	91061|Bacilli	S	Protein of unknown function (DUF2621)	yneK	-	-	-	-	-	-	-	-	-	-	-	DUF2621
REGS1_k127_5846429_4	580332.Slit_1254	2.012e-140	452.0	COG0697@1|root,COG0697@2|Bacteria,1QQY8@1224|Proteobacteria,2VN44@28216|Betaproteobacteria,44VEW@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
REGS1_k127_5846429_8	580332.Slit_1491	6.834e-99	327.0	COG1573@1|root,COG1573@2|Bacteria,1MW91@1224|Proteobacteria,2VQ3T@28216|Betaproteobacteria	28216|Betaproteobacteria	L	uracil-DNA glycosylase	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
REGS1_k127_5846429_11	580332.Slit_1623	1.694e-94	317.0	COG0566@1|root,COG0566@2|Bacteria,1R9JA@1224|Proteobacteria,2VQDG@28216|Betaproteobacteria,44VNV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SpoU rRNA Methylase family	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_5846429_14	395494.Galf_1592	5.257e-70	245.0	COG1386@1|root,COG1386@2|Bacteria,1PUA6@1224|Proteobacteria,2VKIN@28216|Betaproteobacteria,44VTG@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Segregation and condensation complex subunit ScpB	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
REGS1_k127_5846429_6	580332.Slit_1625	3.115e-128	418.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,2VKE7@28216|Betaproteobacteria,44VJ2@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
REGS1_k127_5846429_0	580332.Slit_1626	2.714e-244	756.0	COG0180@1|root,COG0180@2|Bacteria,1MV4T@1224|Proteobacteria,2VIEY@28216|Betaproteobacteria,44V3N@713636|Nitrosomonadales	28216|Betaproteobacteria	J	tRNA synthetases class I (W and Y)	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
REGS1_k127_5846429_12	395494.Galf_1595	1.344e-86	293.0	COG1994@1|root,COG1994@2|Bacteria,1NSFF@1224|Proteobacteria,2VHAM@28216|Betaproteobacteria,44VNY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
REGS1_k127_5846429_9	580332.Slit_1629	3.011e-98	324.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VH4T@28216|Betaproteobacteria,44VHQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	TIGRFAM Sua5 YciO YrdC YwlC family protein	yciO	-	-	-	-	-	-	-	-	-	-	-	Sua5_yciO_yrdC
REGS1_k127_5846429_7	580332.Slit_1630	8.965e-127	414.0	COG0613@1|root,COG0613@2|Bacteria,1MWIH@1224|Proteobacteria,2VHB2@28216|Betaproteobacteria,44VHP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DNA polymerase alpha chain like domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
REGS1_k127_5846429_17	395494.Galf_1598	8.008e-41	154.0	COG2914@1|root,COG2914@2|Bacteria,1MZCH@1224|Proteobacteria,2VVNX@28216|Betaproteobacteria,44VZ5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0125 (RnfH) family	rnfH	-	-	ko:K09801	-	-	-	-	ko00000	-	-	-	Ub-RnfH
REGS1_k127_5846429_15	395494.Galf_1599	2.063e-66	229.0	COG2867@1|root,COG2867@2|Bacteria,1RGUH@1224|Proteobacteria,2VR4X@28216|Betaproteobacteria,44VUY@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Polyketide cyclase / dehydrase and lipid transport	ratA	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
REGS1_k127_5846429_13	395494.Galf_1600	1.994e-73	249.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,2VRG9@28216|Betaproteobacteria,44VSM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
REGS1_k127_5846429_2	1121013.P873_12775	1.449e-146	486.0	COG2114@1|root,COG5000@1|root,COG2114@2|Bacteria,COG5000@2|Bacteria,1MV1V@1224|Proteobacteria,1RYBQ@1236|Gammaproteobacteria,1X8HM@135614|Xanthomonadales	135614|Xanthomonadales	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_5846429_5	1485544.JQKP01000014_gene1857	2.056e-138	452.0	COG2358@1|root,COG2358@2|Bacteria,1PNJV@1224|Proteobacteria,2VI8H@28216|Betaproteobacteria	28216|Betaproteobacteria	S	TRAP transporter solute receptor TAXI family	-	-	-	-	-	-	-	-	-	-	-	-	NMT1_3
REGS1_k127_5846429_1	580332.Slit_2138	9.562e-190	598.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,2VH4J@28216|Betaproteobacteria,44V96@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter C-terminal domain	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
REGS1_k127_5851707_5	1163617.SCD_n00343	8.426e-83	289.0	COG3850@1|root,COG3850@2|Bacteria,1MWZT@1224|Proteobacteria,2VIFM@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	narX	-	2.7.13.3	ko:K07673	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,HAMP,HATPase_c,HisKA_3,PilJ
REGS1_k127_5851707_6	1485544.JQKP01000015_gene2081	1.489e-81	276.0	COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria,44WAG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	narL	-	-	ko:K07684	ko02020,map02020	M00471	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
REGS1_k127_5851707_17	179408.Osc7112_5669	8.078e-26	112.0	2EE9F@1|root,3383V@2|Bacteria,1G6VP@1117|Cyanobacteria,1HBXW@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5851707_14	85643.Tmz1t_2663	3.195e-37	144.0	COG4968@1|root,COG4968@2|Bacteria,1MZZW@1224|Proteobacteria,2VU8H@28216|Betaproteobacteria,2KX3T@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type IV minor pilin ComP, DNA uptake sequence receptor	pilE	-	-	ko:K02655	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	ComP_DUS,N_methyl
REGS1_k127_5851707_15	1485544.JQKP01000002_gene1380	8.517e-37	147.0	COG4970@1|root,COG4970@2|Bacteria,1NA9B@1224|Proteobacteria,2VV1S@28216|Betaproteobacteria,44W1X@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type II transport protein GspH	-	-	-	ko:K08084	-	-	-	-	ko00000,ko02044	3.A.15.2	-	-	GspH,N_methyl
REGS1_k127_5851707_13	1485544.JQKP01000002_gene1379	1.021e-39	152.0	COG4967@1|root,COG4967@2|Bacteria,1N7AC@1224|Proteobacteria,2VW8B@28216|Betaproteobacteria,44W3Z@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	type IV pilus modification protein PilV	-	-	-	ko:K02671	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
REGS1_k127_5851707_9	1485544.JQKP01000002_gene1378	1.653e-54	203.0	COG4966@1|root,COG4966@2|Bacteria,1RH2G@1224|Proteobacteria,2VT5C@28216|Betaproteobacteria,44W2N@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Type IV Pilus-assembly protein W	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl,PilW
REGS1_k127_5851707_12	1485544.JQKP01000002_gene1377	3.227e-41	162.0	COG4726@1|root,COG4726@2|Bacteria,1N9CE@1224|Proteobacteria,2VWPP@28216|Betaproteobacteria,44W26@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein PilX	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5851707_0	1485544.JQKP01000002_gene1376	1.802e-294	969.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,2VHY8@28216|Betaproteobacteria,44V4V@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Neisseria PilC beta-propeller domain	pilY1	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
REGS1_k127_5851707_3	580332.Slit_2081	1.364e-147	475.0	COG0665@1|root,COG0665@2|Bacteria,1MVIZ@1224|Proteobacteria,2WAJ5@28216|Betaproteobacteria,44VDR@713636|Nitrosomonadales	28216|Betaproteobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
REGS1_k127_5851707_1	580332.Slit_1010	6.02e-263	811.0	COG1158@1|root,COG1158@2|Bacteria,1MUCF@1224|Proteobacteria,2VJ2E@28216|Betaproteobacteria,44VCZ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
REGS1_k127_5851707_8	580332.Slit_1011	4.886e-62	214.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria,44VWK@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Thioredoxin	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
REGS1_k127_5851707_18	395493.BegalDRAFT_2965	1.456e-24	109.0	2EVMX@1|root,33P1X@2|Bacteria,1NK24@1224|Proteobacteria,1SIT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CheW
REGS1_k127_5851707_2	765913.ThidrDRAFT_0025	1.248e-241	789.0	COG0643@1|root,COG0643@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,1WWZQ@135613|Chromatiales	135613|Chromatiales	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_5851707_4	1249627.D779_2642	8.44e-136	454.0	COG0840@1|root,COG4564@1|root,COG0840@2|Bacteria,COG4564@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	chemotaxis, protein	-	-	-	-	-	-	-	-	-	-	-	-	Cache_3-Cache_2,HAMP,MCPsignal
REGS1_k127_5851707_16	765913.ThidrDRAFT_0027	6.015e-32	134.0	COG0835@1|root,COG0835@2|Bacteria,1NF0B@1224|Proteobacteria,1SD1Q@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	CheW-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
REGS1_k127_5851707_10	765913.ThidrDRAFT_0028	1.127e-51	185.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,1S5UT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Response regulator receiver	-	-	-	ko:K02658	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
REGS1_k127_5851707_11	395493.BegalDRAFT_2974	4.982e-42	164.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria,1S364@1236|Gammaproteobacteria,463EC@72273|Thiotrichales	72273|Thiotrichales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_5851707_7	580332.Slit_1520	6.407e-74	250.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,2VJFM@28216|Betaproteobacteria,44VBY@713636|Nitrosomonadales	28216|Betaproteobacteria	L	it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction	rep	-	3.6.4.12	ko:K03656	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
REGS1_k127_5878078_30	395494.Galf_2281	6.871e-23	99.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,44V16@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_5878078_4	1485544.JQKP01000002_gene1535	4.129e-221	687.0	COG0404@1|root,COG0404@2|Bacteria,1MV96@1224|Proteobacteria,2VIT9@28216|Betaproteobacteria,44VKF@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
REGS1_k127_5878078_25	580332.Slit_2860	1.656e-66	228.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,2VSD7@28216|Betaproteobacteria,44VU2@713636|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
REGS1_k127_5878078_7	228410.NE0609	6.81e-205	646.0	COG0403@1|root,COG0403@2|Bacteria,1MVC1@1224|Proteobacteria,2VKQB@28216|Betaproteobacteria,3720Y@32003|Nitrosomonadales	28216|Betaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvPA	-	1.4.4.2	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	-	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko01000	-	-	-	GDC-P
REGS1_k127_5878078_5	697282.Mettu_3556	6.355e-216	678.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RMKV@1236|Gammaproteobacteria,1XE0I@135618|Methylococcales	135618|Methylococcales	E	Amino acid permease	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
REGS1_k127_5878078_12	580332.Slit_0273	1.707e-169	539.0	COG0543@1|root,COG1018@1|root,COG0543@2|Bacteria,COG1018@2|Bacteria,1MV72@1224|Proteobacteria,2VI9K@28216|Betaproteobacteria,44V1J@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain protein	ascD	-	1.17.1.1	ko:K00523	ko00520,map00520	-	R03391,R03392	RC00230	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
REGS1_k127_5878078_20	1485544.JQKP01000002_gene1608	1.249e-84	287.0	COG1587@1|root,COG1587@2|Bacteria,1MWZD@1224|Proteobacteria,2VRU9@28216|Betaproteobacteria,44VS4@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4
REGS1_k127_5878078_13	395494.Galf_2511	1.264e-165	525.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,2VHT4@28216|Betaproteobacteria,44V8C@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
REGS1_k127_5878078_0	580332.Slit_0266	0.0	1414.0	COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,2VI9F@28216|Betaproteobacteria,44V53@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle	ppc	-	4.1.1.31	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00168,M00170,M00171,M00172,M00173,M00346,M00374	R00345	RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPcase
REGS1_k127_5878078_23	76869.PputGB1_0529	3.326e-71	247.0	2B2CQ@1|root,31UX4@2|Bacteria,1RBM3@1224|Proteobacteria,1SBUB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5878078_15	580332.Slit_0260	1.105e-109	360.0	COG3279@1|root,COG3279@2|Bacteria,1MUE8@1224|Proteobacteria,2WEFP@28216|Betaproteobacteria,44V6W@713636|Nitrosomonadales	28216|Betaproteobacteria	K	LytTr DNA-binding domain	algR	-	-	ko:K08083	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
REGS1_k127_5878078_16	580332.Slit_0259	9.434e-109	363.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,2VH9S@28216|Betaproteobacteria,44VQA@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Histidine kinase	algZ	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
REGS1_k127_5878078_2	580332.Slit_0258	4.87e-253	786.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2VH47@28216|Betaproteobacteria,44VK4@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
REGS1_k127_5878078_28	228410.NE1911	4.539e-46	168.0	COG0278@1|root,COG0278@2|Bacteria,1MZ4V@1224|Proteobacteria,2VSCX@28216|Betaproteobacteria,373DG@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the glutaredoxin family. Monothiol subfamily	grxD	-	-	ko:K07390	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Glutaredoxin
REGS1_k127_5878078_9	1485544.JQKP01000001_gene906	1.368e-175	557.0	COG0232@1|root,COG0232@2|Bacteria,1MVQ2@1224|Proteobacteria,2VI7B@28216|Betaproteobacteria,44UZZ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the dGTPase family. Type 2 subfamily	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
REGS1_k127_5878078_10	580332.Slit_0113	3.07e-173	552.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,44VC5@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
REGS1_k127_5878078_24	580332.Slit_0113	1.413e-69	242.0	COG0337@1|root,COG0703@1|root,COG0337@2|Bacteria,COG0703@2|Bacteria,1MUBK@1224|Proteobacteria,2VHXR@28216|Betaproteobacteria,44VC5@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase,SKI
REGS1_k127_5878078_6	395494.Galf_0162	2.271e-215	689.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,2VHY4@28216|Betaproteobacteria,44V2I@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM type II and III secretion system protein	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
REGS1_k127_5878078_27	580332.Slit_0111	2.409e-46	172.0	COG3168@1|root,COG3168@2|Bacteria,1RI6V@1224|Proteobacteria,2VSVR@28216|Betaproteobacteria,44VWM@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein, PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
REGS1_k127_5878078_21	580332.Slit_0110	1.523e-76	261.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,2VH68@28216|Betaproteobacteria,44VQQ@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
REGS1_k127_5878078_26	580332.Slit_0109	8.102e-56	203.0	COG3166@1|root,COG3166@2|Bacteria,1RF1S@1224|Proteobacteria,2VN9T@28216|Betaproteobacteria,44VS1@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
REGS1_k127_5878078_11	580332.Slit_0108	8.796e-171	542.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,2VH6W@28216|Betaproteobacteria,44VBU@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	TIGRFAM type IV pilus assembly protein PilM	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
REGS1_k127_5878078_1	580332.Slit_0107	0.0	1079.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,2VHXF@28216|Betaproteobacteria,44V5E@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Penicillin-binding protein OB-like domain	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	PCB_OB,Transgly,Transpeptidase
REGS1_k127_5878078_19	580332.Slit_0106	8.352e-98	322.0	COG2413@1|root,COG2413@2|Bacteria,1RFTH@1224|Proteobacteria,2VJC9@28216|Betaproteobacteria,44VRE@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5878078_8	580332.Slit_0037	3.004e-194	608.0	COG0113@1|root,COG0113@2|Bacteria,1MWMW@1224|Proteobacteria,2VHC6@28216|Betaproteobacteria,44VC7@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
REGS1_k127_5878078_17	580332.Slit_0038	1.392e-102	342.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,2VIKF@28216|Betaproteobacteria,44V31@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
REGS1_k127_5878078_3	580332.Slit_0039	3.56e-246	763.0	COG0001@1|root,COG0001@2|Bacteria,1MUY5@1224|Proteobacteria,2VHK9@28216|Betaproteobacteria,44V4H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_5878078_22	580332.Slit_0040	2.998e-72	250.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,2VSR5@28216|Betaproteobacteria,44VTH@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
REGS1_k127_5878078_14	580332.Slit_0041	1.218e-150	480.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2VKD2@28216|Betaproteobacteria,44V55@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
REGS1_k127_5878078_18	748247.AZKH_0930	2.481e-99	330.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,2VH15@28216|Betaproteobacteria,2KUK6@206389|Rhodocyclales	206389|Rhodocyclales	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
REGS1_k127_5882842_15	1217720.ALOX01000027_gene3732	1.406e-93	314.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,2TRJT@28211|Alphaproteobacteria,2JS2M@204441|Rhodospirillales	204441|Rhodospirillales	S	Catalytic LigB subunit of aromatic ring-opening dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	LigB
REGS1_k127_5882842_5	1485544.JQKP01000001_gene1235	7.719e-187	591.0	COG0477@1|root,COG2814@2|Bacteria,1MVZI@1224|Proteobacteria,2VHWT@28216|Betaproteobacteria,44UYH@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Nucleoside H+ symporter	hcaT	-	-	ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27	-	-	MFS_1_like
REGS1_k127_5882842_16	580332.Slit_2129	9.427e-72	247.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,2VSEQ@28216|Betaproteobacteria,44VPQ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
REGS1_k127_5882842_0	580332.Slit_2130	0.0	1111.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,44V2Z@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Hsp70 protein	dnaK	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
REGS1_k127_5882842_6	522306.CAP2UW1_0504	4.286e-181	573.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,2VHEH@28216|Betaproteobacteria,1KPRY@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
REGS1_k127_5882842_21	765952.PUV_18860	5.398e-17	94.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,DUF285,PKD
REGS1_k127_5882842_9	580332.Slit_2118	1.038e-131	423.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,2VI0R@28216|Betaproteobacteria,44V8K@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
REGS1_k127_5882842_17	580332.Slit_2119	1.394e-42	165.0	COG0619@1|root,COG0619@2|Bacteria,1N7EI@1224|Proteobacteria,2VWJT@28216|Betaproteobacteria,44VYV@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	-	-	-	-	-	-	-	-	-	-	-	-	CbiQ
REGS1_k127_5882842_18	580332.Slit_2120	1.082e-32	146.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,44VR7@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
REGS1_k127_5882842_14	580332.Slit_2120	2.112e-97	337.0	COG3170@1|root,COG3170@2|Bacteria,1MXV7@1224|Proteobacteria,2VHX1@28216|Betaproteobacteria,44VR7@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	pilus assembly protein FimV	fimV	-	-	ko:K08086	-	-	-	-	ko00000	-	-	-	LysM
REGS1_k127_5882842_3	1502770.JQMG01000001_gene2144	3.717e-195	614.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,2VH2N@28216|Betaproteobacteria,2KKMI@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_5882842_2	580332.Slit_2122	2.381e-204	638.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2VH2M@28216|Betaproteobacteria,44VCP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
REGS1_k127_5882842_10	580332.Slit_2123	1.674e-123	397.0	COG0066@1|root,COG0066@2|Bacteria,1MVXB@1224|Proteobacteria,2VIJC@28216|Betaproteobacteria,44V73@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
REGS1_k127_5882842_1	580332.Slit_2125	5.136e-259	803.0	COG0065@1|root,COG0065@2|Bacteria,1MVYR@1224|Proteobacteria,2VHSH@28216|Betaproteobacteria,44V0G@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
REGS1_k127_5882842_13	580332.Slit_1346	1.083e-109	355.0	COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,44VV7@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
REGS1_k127_5882842_11	395494.Galf_2062	9.289e-116	404.0	COG2202@1|root,COG2203@1|root,COG4585@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4585@2|Bacteria,1NWNJ@1224|Proteobacteria	1224|Proteobacteria	T	PAS domain containing protein	-	-	2.7.13.3,3.1.3.3	ko:K07315,ko:K07675	ko02020,map02020	M00473	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko03021	-	-	-	EAL,GAF_2,GGDEF,HATPase_c,HisKA_2,HisKA_3,PAS_3,PAS_4,PAS_8,PAS_9,SpoIIE,dCache_1
REGS1_k127_5882842_19	1353531.AZNX01000005_gene3293	6.972e-30	138.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TR8X@28211|Alphaproteobacteria,4B9N5@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9
REGS1_k127_5882842_12	580332.Slit_1984	8.346e-110	358.0	COG2085@1|root,COG2085@2|Bacteria,1NI54@1224|Proteobacteria,2VNIB@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
REGS1_k127_5882842_7	580332.Slit_1983	5.418e-167	529.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2WEDQ@28216|Betaproteobacteria,44VB3@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppB	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_5882842_22	580332.Slit_0348	0.0004217	42.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,2VHDR@28216|Betaproteobacteria,44VK7@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
REGS1_k127_5882842_4	1485544.JQKP01000004_gene508	1.796e-188	600.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,2VHWM@28216|Betaproteobacteria,44VGE@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	oppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_5882842_8	580332.Slit_1981	2.292e-132	431.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,44V4B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	dppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
REGS1_k127_589751_9	859657.RPSI07_mp0896	8.171e-40	149.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,2VJFX@28216|Betaproteobacteria,1K04I@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.1,1.6.5.5	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
REGS1_k127_589751_13	398512.JQKC01000013_gene1464	8.143e-10	71.0	COG5113@1|root,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,3WGS9@541000|Ruminococcaceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
REGS1_k127_589751_6	3988.XP_002538111.1	8.839e-63	232.0	COG1397@1|root,2RZ0J@2759|Eukaryota,382DP@33090|Viridiplantae	33090|Viridiplantae	G	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
REGS1_k127_589751_2	395494.Galf_0057	2.764e-240	752.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,2VIX5@28216|Betaproteobacteria,44V06@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_589751_7	580332.Slit_0053	3.397e-58	203.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,44VXF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
REGS1_k127_589751_4	580332.Slit_0129	3.268e-106	351.0	COG4221@1|root,COG4221@2|Bacteria,1QTVZ@1224|Proteobacteria,2WGPF@28216|Betaproteobacteria,44UYR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_589751_5	1485544.JQKP01000002_gene1493	6.287e-64	225.0	COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,2VSFV@28216|Betaproteobacteria,44VUB@713636|Nitrosomonadales	28216|Betaproteobacteria	O	DSBA-like thioredoxin domain	dsbA	-	-	ko:K03673	ko01503,map01503	M00728	-	-	ko00000,ko00001,ko00002,ko03110	-	-	-	DSBA,Thioredoxin_4
REGS1_k127_589751_10	580332.Slit_0127	1.161e-32	134.0	COG3087@1|root,COG3087@2|Bacteria,1N4QG@1224|Proteobacteria,2VUXF@28216|Betaproteobacteria,44VZ6@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
REGS1_k127_589751_0	580332.Slit_0126	9.077e-308	949.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,2VHT1@28216|Betaproteobacteria,44V7S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
REGS1_k127_589751_8	323848.Nmul_A0198	3.086e-47	175.0	COG2062@1|root,COG2062@2|Bacteria,1RIVH@1224|Proteobacteria,2VSSQ@28216|Betaproteobacteria,37363@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Phosphoglycerate mutase family	sixA	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
REGS1_k127_589751_1	580332.Slit_2953	1.957e-247	771.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,2VGZV@28216|Betaproteobacteria,44VMC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Polyphosphate kinase 2 (PPK2)	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
REGS1_k127_589751_3	324925.Ppha_0637	1.677e-211	675.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1FDGV@1090|Chlorobi	2|Bacteria	H	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8
REGS1_k127_589751_11	697282.Mettu_0305	1.17e-14	75.0	COG2326@1|root,COG2326@2|Bacteria,1MVE2@1224|Proteobacteria,1RM9U@1236|Gammaproteobacteria,1XE6M@135618|Methylococcales	135618|Methylococcales	S	PFAM Polyphosphate kinase 2	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
REGS1_k127_589751_12	1541960.KQ78_00217	1.123e-13	74.0	28IEP@1|root,2Z8GP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5903763_12	1485544.JQKP01000011_gene728	4.783e-28	114.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,44VP0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
REGS1_k127_5903763_1	1485544.JQKP01000004_gene528	7.295e-194	615.0	COG3659@1|root,COG3659@2|Bacteria,1Q8C7@1224|Proteobacteria,2VJFC@28216|Betaproteobacteria,44W6W@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Carbohydrate-selective porin, OprB family	oprB	-	-	-	-	-	-	-	-	-	-	-	OprB
REGS1_k127_5903763_10	580332.Slit_1249	6.527e-57	209.0	2B47E@1|root,31WYM@2|Bacteria,1R5Q0@1224|Proteobacteria,2VT47@28216|Betaproteobacteria,44WI4@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_5903763_3	580332.Slit_0690	2.791e-142	458.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,2VJIA@28216|Betaproteobacteria,44VBC@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ABC transporter	ttg2A	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
REGS1_k127_5903763_4	1485544.JQKP01000001_gene1100	5.816e-133	427.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,2VI5T@28216|Betaproteobacteria,44VFH@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	Permease MlaE	ttg2B	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
REGS1_k127_5903763_8	395494.Galf_0537	4.91e-67	231.0	COG1463@1|root,COG1463@2|Bacteria,1NCUG@1224|Proteobacteria,2VRKR@28216|Betaproteobacteria,44VUD@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	PFAM Mammalian cell entry related domain protein	mlaD	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
REGS1_k127_5903763_9	580332.Slit_0693	4.883e-63	225.0	COG2854@1|root,COG2854@2|Bacteria,1NKFA@1224|Proteobacteria,2VR85@28216|Betaproteobacteria,44VY5@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	MlaC protein	ttg2D	-	-	ko:K07323	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	MlaC
REGS1_k127_5903763_13	395494.Galf_0539	2.118e-17	87.0	COG3113@1|root,COG3113@2|Bacteria,1NGIE@1224|Proteobacteria,2WB4W@28216|Betaproteobacteria,44W3G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Sulfate transporter antisigma-factor antagonist STAS	-	-	-	ko:K07122	ko02010,map02010	M00210	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27.3	-	-	STAS_2
REGS1_k127_5903763_5	1288494.EBAPG3_9350	2.499e-128	416.0	COG1131@1|root,COG1131@2|Bacteria,1MUW7@1224|Proteobacteria,2VI81@28216|Betaproteobacteria,3726R@32003|Nitrosomonadales	28216|Betaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ybhF_1	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_5903763_7	1123487.KB892865_gene1482	6.248e-109	359.0	COG0842@1|root,COG0842@2|Bacteria,1MUH1@1224|Proteobacteria,2VH42@28216|Betaproteobacteria,2KUGF@206389|Rhodocyclales	206389|Rhodocyclales	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
REGS1_k127_5903763_11	1485544.JQKP01000001_gene1104	3.199e-29	117.0	COG5007@1|root,COG5007@2|Bacteria,1MZCZ@1224|Proteobacteria,2VU0K@28216|Betaproteobacteria,44W19@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the BolA IbaG family	yrbA	-	-	-	-	-	-	-	-	-	-	-	BolA
REGS1_k127_5903763_0	580332.Slit_0695	2.995e-226	705.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,2VHZN@28216|Betaproteobacteria,44VFJ@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
REGS1_k127_5903763_6	580332.Slit_0696	6.517e-114	370.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2VIF9@28216|Betaproteobacteria,44V3X@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
REGS1_k127_5903763_2	580332.Slit_0697	4.567e-193	608.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,44V4T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
REGS1_k127_5951856_0	580332.Slit_1654	2.957e-254	793.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1MU9U@1224|Proteobacteria,2VJ8C@28216|Betaproteobacteria,44V57@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.1.5,6.3.5.1	ko:K01916,ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00189,R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
REGS1_k127_5951856_4	335543.Sfum_3514	1.365e-35	144.0	COG3034@1|root,COG3034@2|Bacteria,1QTMV@1224|Proteobacteria,42W1K@68525|delta/epsilon subdivisions,2X5QE@28221|Deltaproteobacteria,2MS74@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_5951856_2	1123487.KB892834_gene2622	1.389e-126	422.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	Z012_00180	-	3.1.1.5	ko:K10804	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	Lipase_GDSL,Lipase_GDSL_2,LysM
REGS1_k127_5951856_3	1123487.KB892834_gene2621	1.503e-95	324.0	COG2845@1|root,COG2845@2|Bacteria,1R4X7@1224|Proteobacteria,2VJAR@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF459)	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
REGS1_k127_5951856_1	1123487.KB892834_gene2620	8.723e-127	416.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,2VISD@28216|Betaproteobacteria,2KUFR@206389|Rhodocyclales	206389|Rhodocyclales	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
REGS1_k127_5968347_11	1485544.JQKP01000012_gene2150	4.429e-24	102.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,44VDV@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
REGS1_k127_5968347_7	1150469.RSPPHO_01171	1.333e-77	267.0	COG4122@1|root,COG4122@2|Bacteria,1MYYK@1224|Proteobacteria,2UADT@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Macrocin-O-methyltransferase (TylF)	-	-	-	-	-	-	-	-	-	-	-	-	TylF
REGS1_k127_5968347_1	580332.Slit_0447	4.39e-199	627.0	COG0304@1|root,COG0304@2|Bacteria,1MV30@1224|Proteobacteria,2VI0P@28216|Betaproteobacteria,44VP8@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Beta-ketoacyl synthase, C-terminal domain	-	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
REGS1_k127_5968347_9	395494.Galf_1157	1.378e-30	122.0	COG0236@1|root,COG0236@2|Bacteria,1NGVI@1224|Proteobacteria,2VXRY@28216|Betaproteobacteria,44W32@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
REGS1_k127_5968347_4	1485544.JQKP01000002_gene1388	1.046e-118	389.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,2VQE7@28216|Betaproteobacteria,44V1F@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
REGS1_k127_5968347_0	1485544.JQKP01000002_gene1389	0.0	1129.0	COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,1MU0A@1224|Proteobacteria,2VIYB@28216|Betaproteobacteria,44VKP@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Malic enzyme, NAD binding domain	maeB	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malate_DH,Malic_M,PTA_PTB,malic
REGS1_k127_5968347_2	580332.Slit_0452	2.866e-164	525.0	COG1752@1|root,COG1752@2|Bacteria,1PIHH@1224|Proteobacteria,2VHKX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
REGS1_k127_5968347_5	580332.Slit_0453	2.964e-118	389.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,2VNXD@28216|Betaproteobacteria,44VHY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
REGS1_k127_5968347_6	580332.Slit_0454	1.548e-83	283.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,2VK1G@28216|Betaproteobacteria,44VXV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33,6.3.4.15	ko:K01947,ko:K03525	ko00770,ko00780,ko01100,map00770,map00780,map01100	M00120	R01074,R02971,R03018,R04391,R05145	RC00002,RC00017,RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko00002,ko01000	-	-	-	BPL_C,BPL_LplA_LipB,Pan_kinase
REGS1_k127_5968347_8	580332.Slit_0455	1.155e-55	203.0	2DP0A@1|root,3300Q@2|Bacteria,1N78Y@1224|Proteobacteria,2VVZ5@28216|Betaproteobacteria,44VYM@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Sporulation domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
REGS1_k127_5968347_3	1121439.dsat_1526	3.508e-127	419.0	COG0582@1|root,COG0582@2|Bacteria,1MU23@1224|Proteobacteria,42N7I@68525|delta/epsilon subdivisions,2WKY2@28221|Deltaproteobacteria,2M8MH@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_3,Phage_integrase
REGS1_k127_5968347_10	686340.Metal_3169	9.833e-30	120.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	msr0960	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
REGS1_k127_5968347_13	580332.Slit_2135	1.454e-07	56.0	COG3146@1|root,COG3146@2|Bacteria,1MU35@1224|Proteobacteria,2VH0Z@28216|Betaproteobacteria	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09919	-	-	-	-	ko00000	-	-	-	FemAB_like
REGS1_k127_598274_1	1485544.JQKP01000001_gene928	3.483e-188	592.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,44VDQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
REGS1_k127_598274_2	580332.Slit_2745	9.287e-91	302.0	COG0212@1|root,COG0212@2|Bacteria,1PWVW@1224|Proteobacteria,2WCEJ@28216|Betaproteobacteria,44VWT@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
REGS1_k127_598274_4	580332.Slit_2744	1.306e-34	135.0	COG3070@1|root,COG3070@2|Bacteria,1PJWV@1224|Proteobacteria,2W88N@28216|Betaproteobacteria,44WJI@713636|Nitrosomonadales	28216|Betaproteobacteria	K	TfoX N-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
REGS1_k127_598274_0	580332.Slit_2743	2.927e-296	912.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2VI5U@28216|Betaproteobacteria,44UZX@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
REGS1_k127_598274_3	580332.Slit_2733	3.65e-55	195.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,44VEN@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A,Sugar-bind
REGS1_k127_6046501_4	580332.Slit_2641	1.925e-18	92.0	298CZ@1|root,2ZVIA@2|Bacteria,1PATN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6046501_2	580332.Slit_2642	7.781e-48	175.0	2CDU4@1|root,348SV@2|Bacteria,1P0YW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6046501_1	580332.Slit_2643	6.777e-171	546.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	ko:K02574	-	-	-	-	ko00000	-	-	-	Fer4_10,Fer4_18,Fer4_5,FixG_C
REGS1_k127_6046501_0	580332.Slit_2644	2.278e-273	870.0	COG4262@1|root,COG4262@2|Bacteria,1RFPU@1224|Proteobacteria,2VQJ5@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Spermidine synthase	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_6046501_3	580332.Slit_2645	2.095e-20	95.0	2CDU5@1|root,2ZDGN@2|Bacteria,1P8N2@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6046501_5	314345.SPV1_07361	1.946e-08	57.0	29AAB@1|root,2ZXB0@2|Bacteria,1P7IN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6135535_20	1286093.C266_14114	3.786e-29	122.0	2C2EC@1|root,32S1H@2|Bacteria,1MZBC@1224|Proteobacteria,2VVF0@28216|Betaproteobacteria,1KAWY@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6135535_4	1144342.PMI40_01685	3.073e-212	670.0	COG3497@1|root,COG3497@2|Bacteria,1R3SE@1224|Proteobacteria,2VPMY@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Phage tail sheath protein subtilisin-like domain	-	-	-	ko:K06907	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_6135535_15	580332.Slit_1910	1.613e-71	254.0	2BV62@1|root,32QJE@2|Bacteria,1RM1Z@1224|Proteobacteria,2VTTH@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6135535_22	666681.M301_0865	2.029e-24	108.0	2BKHD@1|root,2ZGSD@2|Bacteria,1P4ZX@1224|Proteobacteria,2W55F@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6135535_23	1562701.BBOF01000006_gene72	7.332e-16	81.0	2C74J@1|root,33MFT@2|Bacteria,1NHBS@1224|Proteobacteria,2VY56@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6135535_19	580332.Slit_1926	1.279e-32	132.0	2BYTR@1|root,33FQK@2|Bacteria,1NPZX@1224|Proteobacteria,2VXW4@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6135535_16	1070319.CAGGBEG34_350029	8.337e-46	180.0	COG3935@1|root,COG3935@2|Bacteria,1N8GP@1224|Proteobacteria,2VUHE@28216|Betaproteobacteria	28216|Betaproteobacteria	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6135535_0	580332.Slit_1608	0.0	1017.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,2VHW2@28216|Betaproteobacteria,44W82@713636|Nitrosomonadales	28216|Betaproteobacteria	C	NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding	hoxF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
REGS1_k127_6135535_11	580332.Slit_1609	6.085e-126	407.0	COG1034@1|root,COG1034@2|Bacteria,1QVC7@1224|Proteobacteria,2VI6U@28216|Betaproteobacteria,44W9N@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding	hoxU	-	1.12.1.2	ko:K18006	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
REGS1_k127_6135535_12	580332.Slit_1610	1.249e-110	360.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,2VJH8@28216|Betaproteobacteria,44WAW@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	hoxY	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
REGS1_k127_6135535_2	580332.Slit_1611	1.873e-301	927.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,44WEG@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hoxH	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
REGS1_k127_6135535_17	580332.Slit_1612	2.081e-42	166.0	COG0680@1|root,COG0680@2|Bacteria,1MZE1@1224|Proteobacteria,2VTPX@28216|Betaproteobacteria,44WKQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	hydrogenase maturation protease	hoxW	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6135535_14	522306.CAP2UW1_2510	3.027e-86	290.0	COG1014@1|root,COG1014@2|Bacteria,1N12F@1224|Proteobacteria,2VQ8C@28216|Betaproteobacteria	28216|Betaproteobacteria	C	TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit	porC	-	1.2.1.58,1.2.7.1	ko:K00172,ko:K18357	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
REGS1_k127_6135535_3	522306.CAP2UW1_2511	3.02e-222	693.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,2VJSA@28216|Betaproteobacteria	28216|Betaproteobacteria	C	pyruvate flavodoxin ferredoxin oxidoreductase	porA	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
REGS1_k127_6135535_8	338969.Rfer_2185	9.053e-170	540.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,2VKQX@28216|Betaproteobacteria,4AH00@80864|Comamonadaceae	28216|Betaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	porB	-	1.2.1.58,1.2.7.1	ko:K00170,ko:K18356	ko00010,ko00020,ko00360,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00360,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R02450,R08034	RC00004,RC00250,RC02742,RC02833,RC02860	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_11,Fer4_6,TPP_enzyme_C
REGS1_k127_6135535_1	395494.Galf_0059	3.238e-309	961.0	COG0493@1|root,COG1144@1|root,COG0493@2|Bacteria,COG1144@2|Bacteria,1MU2H@1224|Proteobacteria,2VM9R@28216|Betaproteobacteria,44V9S@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_21,Pyr_redox_2,Pyr_redox_3
REGS1_k127_6135535_18	580332.Slit_2425	6.1e-39	148.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,2VUFZ@28216|Betaproteobacteria,44WI7@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
REGS1_k127_6135535_10	580332.Slit_2424	4.064e-128	416.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,2VJKH@28216|Betaproteobacteria,44W6Q@713636|Nitrosomonadales	28216|Betaproteobacteria	KO	PFAM cobalamin synthesis protein P47K	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
REGS1_k127_6135535_9	580332.Slit_2423	1.533e-140	454.0	COG0068@1|root,COG0068@2|Bacteria,1MVP8@1224|Proteobacteria,2VHS4@28216|Betaproteobacteria,44W7Y@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
REGS1_k127_6135535_21	580332.Slit_2422	2.188e-26	113.0	COG0298@1|root,COG0298@2|Bacteria,1N76Y@1224|Proteobacteria,2VVZH@28216|Betaproteobacteria,44WJT@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
REGS1_k127_6135535_6	580332.Slit_2421	1.573e-206	646.0	COG0409@1|root,COG0409@2|Bacteria,1MU1F@1224|Proteobacteria,2VHKM@28216|Betaproteobacteria,44W7R@713636|Nitrosomonadales	28216|Betaproteobacteria	O	TIGRFAM hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
REGS1_k127_6135535_7	580332.Slit_2419	2.36e-181	575.0	COG0309@1|root,COG0309@2|Bacteria,1MVCC@1224|Proteobacteria,2VH3K@28216|Betaproteobacteria,44W8A@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM AIR synthase related protein domain protein	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
REGS1_k127_6135535_13	580332.Slit_2550	3.733e-100	339.0	COG1394@1|root,COG1394@2|Bacteria,1PA1A@1224|Proteobacteria,2W26X@28216|Betaproteobacteria	28216|Betaproteobacteria	C	ATP synthase subunit D	-	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
REGS1_k127_6135535_5	580332.Slit_2551	6.111e-208	649.0	COG1156@1|root,COG1156@2|Bacteria,1QUQE@1224|Proteobacteria	1224|Proteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	-	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab
REGS1_k127_6147247_0	580332.Slit_2746	0.0	1037.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,2VIAH@28216|Betaproteobacteria,44VDQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
REGS1_k127_6147247_4	396588.Tgr7_2455	3.145e-154	498.0	COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,1WW8D@135613|Chromatiales	135613|Chromatiales	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
REGS1_k127_6147247_6	580332.Slit_2748	1.836e-91	305.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,2VSQ7@28216|Betaproteobacteria,44VUN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_6147247_13	1485544.JQKP01000001_gene925	1.964e-43	163.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,2VRRV@28216|Betaproteobacteria,44VZP@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
REGS1_k127_6147247_12	1485544.JQKP01000001_gene924	1.628e-73	250.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,2VQ2M@28216|Betaproteobacteria,44VPN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
REGS1_k127_6147247_8	580332.Slit_2751	5.615e-81	276.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,2VQC3@28216|Betaproteobacteria,44VR4@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
REGS1_k127_6147247_2	1485544.JQKP01000001_gene922	6.903e-253	788.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VI3N@28216|Betaproteobacteria,44VGZ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM RNA-binding protein AU-1 Ribonuclease E G	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
REGS1_k127_6147247_3	296591.Bpro_5550	1.907e-186	587.0	COG1902@1|root,COG1902@2|Bacteria,1MVIX@1224|Proteobacteria,2VH2S@28216|Betaproteobacteria,4A9SH@80864|Comamonadaceae	28216|Betaproteobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	ko:K10680	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN
REGS1_k127_6147247_7	580332.Slit_2772	5.806e-83	283.0	COG4944@1|root,COG4944@2|Bacteria	2|Bacteria	K	Protein of unknown function (DUF1109)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1109
REGS1_k127_6147247_11	1163617.SCD_n02597	3.569e-75	256.0	COG1595@1|root,COG1595@2|Bacteria,1MVS7@1224|Proteobacteria,2VRBF@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE9	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_6147247_9	1163617.SCD_n02613	9.405e-81	271.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VRS3@28216|Betaproteobacteria	28216|Betaproteobacteria	O	methionine sulfoxide reductase	msrB2	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
REGS1_k127_6147247_1	580332.Slit_2768	4.05e-268	834.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1MVV0@1224|Proteobacteria,2W9SN@28216|Betaproteobacteria,44WNI@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM cytochrome c biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
REGS1_k127_6147247_10	580332.Slit_2770	1.083e-76	265.0	2B96M@1|root,322HU@2|Bacteria,1RIIU@1224|Proteobacteria,2VT7Z@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	FecR
REGS1_k127_6147247_5	580332.Slit_2767	1.223e-91	306.0	COG0225@1|root,COG0225@2|Bacteria,1MVUS@1224|Proteobacteria,2VKRT@28216|Betaproteobacteria,44VRJ@713636|Nitrosomonadales	1224|Proteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
REGS1_k127_6147247_14	1485544.JQKP01000019_gene32	1.888e-31	123.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,2VSP2@28216|Betaproteobacteria,44VRM@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	pgpA	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
REGS1_k127_6169554_6	580332.Slit_2296	5.149e-48	174.0	2C9B9@1|root,32RP0@2|Bacteria,1MZKM@1224|Proteobacteria,2WCFP@28216|Betaproteobacteria,44VZH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM HopJ type III effector protein	-	-	-	-	-	-	-	-	-	-	-	-	HopJ
REGS1_k127_6169554_0	580332.Slit_2298	3.081e-239	743.0	COG2265@1|root,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,2VHJ8@28216|Betaproteobacteria,44VEY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA	rlmD	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
REGS1_k127_6169554_3	580332.Slit_2299	1.59e-148	472.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,2VISP@28216|Betaproteobacteria,44V01@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
REGS1_k127_6169554_7	1121035.AUCH01000016_gene2171	1.532e-33	134.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,2KWQ3@206389|Rhodocyclales	206389|Rhodocyclales	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
REGS1_k127_6169554_5	1458275.AZ34_13125	2.492e-71	248.0	COG0625@1|root,COG0625@2|Bacteria,1MY47@1224|Proteobacteria,2VI89@28216|Betaproteobacteria,4AB74@80864|Comamonadaceae	28216|Betaproteobacteria	O	Glutathione S-transferase	gst	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N,GST_N_2,GST_N_3
REGS1_k127_6169554_8	1144319.PMI16_04267	1.678e-31	130.0	COG4731@1|root,COG4731@2|Bacteria,1N19Y@1224|Proteobacteria,2VTB1@28216|Betaproteobacteria,474EH@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2147
REGS1_k127_6169554_1	580332.Slit_1805	4.045e-192	608.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,2VING@28216|Betaproteobacteria,44V5B@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
REGS1_k127_6169554_4	62928.azo2071	4.332e-107	349.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,2KV8X@206389|Rhodocyclales	206389|Rhodocyclales	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
REGS1_k127_6169554_2	580332.Slit_1803	1.687e-169	535.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,2VIEU@28216|Betaproteobacteria,44V8T@713636|Nitrosomonadales	28216|Betaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
REGS1_k127_6190914_3	580332.Slit_0530	6.726e-79	273.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
REGS1_k127_6190914_0	1485544.JQKP01000019_gene4	6.321e-314	972.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,2VH74@28216|Betaproteobacteria,44V7T@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
REGS1_k127_6190914_1	1485544.JQKP01000019_gene3	2.031e-268	836.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,2VHI9@28216|Betaproteobacteria,44V8P@713636|Nitrosomonadales	28216|Betaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
REGS1_k127_6190914_4	580332.Slit_2446	7.231e-63	219.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2VR35@28216|Betaproteobacteria,44VVR@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
REGS1_k127_6190914_6	580332.Slit_2447	2.195e-34	132.0	COG0828@1|root,COG0828@2|Bacteria,1MZCC@1224|Proteobacteria,2VTZ4@28216|Betaproteobacteria,44W3A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
REGS1_k127_6190914_5	580332.Slit_2568	6.504e-41	158.0	COG3658@1|root,COG3658@2|Bacteria,1N28F@1224|Proteobacteria,2VU1H@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Di-haem cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	DHC
REGS1_k127_6190914_2	580332.Slit_2449	2.417e-218	681.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,44V8E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
REGS1_k127_6300281_16	555778.Hneap_1536	2.57e-19	89.0	299RQ@1|root,2ZWTY@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6300281_18	365044.Pnap_1362	2.644e-12	72.0	2ED0C@1|root,336XB@2|Bacteria,1ND2K@1224|Proteobacteria,2VXBS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6300281_14	395494.Galf_2212	2.92e-27	115.0	COG4575@1|root,COG4575@2|Bacteria,1N6X7@1224|Proteobacteria,2WFR8@28216|Betaproteobacteria,44WIE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF883)	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
REGS1_k127_6300281_15	1163617.SCD_n02115	2.121e-22	100.0	COG5393@1|root,COG5393@2|Bacteria,1NDFU@1224|Proteobacteria,2VX3I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
REGS1_k127_6300281_19	1123392.AQWL01000007_gene1018	0.0001734	48.0	2ERQZ@1|root,33JA7@2|Bacteria,1NP63@1224|Proteobacteria,2VXN1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	YqjK-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YqjK
REGS1_k127_6300281_6	1349767.GJA_4518	9.266e-112	370.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,475P1@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
REGS1_k127_6300281_17	1266925.JHVX01000001_gene2468	1.193e-17	85.0	2EFZF@1|root,339RM@2|Bacteria,1NH6S@1224|Proteobacteria,2W8JG@28216|Betaproteobacteria,373T2@32003|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6300281_12	580332.Slit_2549	1.313e-48	179.0	COG2703@1|root,COG2703@2|Bacteria	2|Bacteria	P	oxygen carrier activity	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	HD_5,Hemerythrin
REGS1_k127_6300281_9	580332.Slit_2177	3.059e-73	248.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,2VT5I@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
REGS1_k127_6300281_5	1380391.JIAS01000001_gene2800	4.717e-125	412.0	COG0717@1|root,COG0717@2|Bacteria,1MVDH@1224|Proteobacteria,2TR5U@28211|Alphaproteobacteria,2JQI3@204441|Rhodospirillales	204441|Rhodospirillales	F	2'-deoxycytidine 5'-triphosphate deaminase (DCD)	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
REGS1_k127_6300281_1	1485544.JQKP01000008_gene1754	1.752e-175	565.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VI5V@28216|Betaproteobacteria,44VTV@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family	oprM	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
REGS1_k127_6300281_0	1485544.JQKP01000008_gene1755	0.0	1522.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,44V8X@713636|Nitrosomonadales	28216|Betaproteobacteria	V	TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family	-	-	-	ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
REGS1_k127_6300281_4	1485544.JQKP01000008_gene1756	3.426e-145	475.0	COG0845@1|root,COG0845@2|Bacteria,1MU78@1224|Proteobacteria,2VINC@28216|Betaproteobacteria,44VJ5@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
REGS1_k127_6300281_10	1485544.JQKP01000008_gene1757	1.845e-54	198.0	COG1309@1|root,COG1309@2|Bacteria,1MZ9E@1224|Proteobacteria,2VV5F@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_C_7,TetR_N
REGS1_k127_6300281_13	882378.RBRH_00943	1.941e-32	127.0	COG1278@1|root,COG1278@2|Bacteria,1N6Q5@1224|Proteobacteria,2VVTG@28216|Betaproteobacteria,1K9CX@119060|Burkholderiaceae	28216|Betaproteobacteria	K	Cold shock protein	cspD	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
REGS1_k127_6300281_8	580332.Slit_2678	2.448e-73	250.0	COG2703@1|root,COG2703@2|Bacteria,1RK9A@1224|Proteobacteria,2VT8G@28216|Betaproteobacteria	28216|Betaproteobacteria	P	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_6300281_3	580332.Slit_1977	1.655e-148	485.0	COG0741@1|root,COG1388@1|root,COG3170@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,COG3170@2|Bacteria,1MWKE@1224|Proteobacteria,2VIR7@28216|Betaproteobacteria,44V2P@713636|Nitrosomonadales	28216|Betaproteobacteria	M	LysM domain	mltD	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
REGS1_k127_6300281_7	316067.Geob_3253	3.174e-80	283.0	COG3391@1|root,COG3391@2|Bacteria,1NT97@1224|Proteobacteria,42RMY@68525|delta/epsilon subdivisions,2WNJD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
REGS1_k127_6300281_2	1485544.JQKP01000004_gene543	1.054e-159	508.0	COG1123@1|root,COG4172@2|Bacteria,1MU09@1224|Proteobacteria,2VH5T@28216|Betaproteobacteria,44V4B@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit	dppF	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
REGS1_k127_6319370_3	1485544.JQKP01000004_gene484	5.169e-21	93.0	COG0607@1|root,COG0607@2|Bacteria,1QAME@1224|Proteobacteria,2W7JQ@28216|Betaproteobacteria,44VZW@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_6319370_0	580332.Slit_2416	2.383e-192	608.0	COG0515@1|root,COG0664@1|root,COG0515@2|Bacteria,COG0664@2|Bacteria,1MV1P@1224|Proteobacteria,2VIE9@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,cNMP_binding
REGS1_k127_6319370_1	1485544.JQKP01000004_gene485	8.915e-164	528.0	COG4783@1|root,COG4783@2|Bacteria,1MVFV@1224|Proteobacteria,2VHAY@28216|Betaproteobacteria,44VK3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M48	yggG_1	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,TPR_19
REGS1_k127_6319370_2	582744.Msip34_1296	2.738e-85	301.0	COG0457@1|root,COG3914@1|root,COG0457@2|Bacteria,COG3914@2|Bacteria,1MVMG@1224|Proteobacteria,2VH3M@28216|Betaproteobacteria,2KKW3@206350|Nitrosomonadales	206350|Nitrosomonadales	O	Glycosyl transferase family 41	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_41,TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
REGS1_k127_6432352_5	580332.Slit_2370	1.151e-72	246.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,2VINI@28216|Betaproteobacteria,44VG7@713636|Nitrosomonadales	28216|Betaproteobacteria	D	TIGRFAM cell division ATP-binding protein FtsE	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
REGS1_k127_6432352_2	1485544.JQKP01000001_gene1197	1.813e-160	512.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,2VHK7@28216|Betaproteobacteria,44V41@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
REGS1_k127_6432352_0	580332.Slit_2368	2.122e-197	624.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,44VBT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_6432352_1	580332.Slit_2367	1.485e-189	601.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,2VH8D@28216|Betaproteobacteria,44UZ0@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase M16 inactive domain	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_6432352_3	580332.Slit_2366	9.584e-83	278.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,2VRD3@28216|Betaproteobacteria,44VUP@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Conserved hypothetical protein 95	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
REGS1_k127_6432352_4	580332.Slit_2365	8.162e-75	257.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,2VMQQ@28216|Betaproteobacteria,44VPS@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
REGS1_k127_6432352_6	1485544.JQKP01000001_gene1202	2.358e-49	176.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,2VTZ1@28216|Betaproteobacteria,44W12@713636|Nitrosomonadales	28216|Betaproteobacteria	C	4Fe-4S binding domain	fdx1	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
REGS1_k127_6523550_5	1485544.JQKP01000003_gene130	1.228e-62	218.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,2VHF7@28216|Betaproteobacteria,44V8E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,S4_2,tRNA-synt_1b
REGS1_k127_6523550_2	580332.Slit_2450	1.442e-153	499.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VHBS@28216|Betaproteobacteria,44V44@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_6523550_1	580332.Slit_2451	1.038e-156	502.0	COG2377@1|root,COG2377@2|Bacteria,1MV4E@1224|Proteobacteria,2VHCE@28216|Betaproteobacteria,44V2W@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling	anmK	-	2.7.1.170	ko:K09001	-	-	-	-	ko00000,ko01000	-	-	-	AnmK
REGS1_k127_6523550_4	398767.Glov_3235	1.246e-84	293.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42QJH@68525|delta/epsilon subdivisions,2X5XR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
REGS1_k127_6523550_6	1073999.BN137_4114	7.014e-08	63.0	COG3755@1|root,COG3755@2|Bacteria,1R4M9@1224|Proteobacteria,1S0YJ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pfam:DUF1311	-	-	-	-	-	-	-	-	-	-	-	-	LprI
REGS1_k127_6523550_0	580332.Slit_2036	8.616e-234	734.0	COG0477@1|root,COG0477@2|Bacteria,1MU46@1224|Proteobacteria,2VHKK@28216|Betaproteobacteria,44VMM@713636|Nitrosomonadales	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
REGS1_k127_6523550_3	580332.Slit_2054	3.411e-130	418.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,2VH69@28216|Betaproteobacteria,44V6M@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
REGS1_k127_652413_15	395494.Galf_2666	5.185e-54	190.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria,44VPE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	MltA specific insert domain	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
REGS1_k127_652413_2	1388763.O165_023140	0.0	1080.0	COG1404@1|root,COG1404@2|Bacteria,1ND93@1224|Proteobacteria,1RZ0J@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
REGS1_k127_652413_8	1282356.H045_21075	4.248e-154	492.0	COG0464@1|root,COG0464@2|Bacteria,1MVVP@1224|Proteobacteria,1RY8X@1236|Gammaproteobacteria,1YSE6@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	O	AAA domain (Cdc48 subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
REGS1_k127_652413_11	580332.Slit_2927	2.563e-111	368.0	COG3511@1|root,COG3511@2|Bacteria,1RCY1@1224|Proteobacteria,2WEZW@28216|Betaproteobacteria,44WCM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Phosphoesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Phosphoesterase
REGS1_k127_652413_9	580332.Slit_2928	6.965e-141	449.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VH7N@28216|Betaproteobacteria,44VA6@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
REGS1_k127_652413_1	1485544.JQKP01000004_gene563	0.0	1300.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,2VJIJ@28216|Betaproteobacteria,44WD2@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_652413_17	640510.BC1001_1874	2.042e-37	140.0	COG3530@1|root,COG3530@2|Bacteria,1N7GT@1224|Proteobacteria,2VW2G@28216|Betaproteobacteria,1K9BT@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
REGS1_k127_652413_16	580332.Slit_2823	2.609e-42	158.0	COG1872@1|root,COG1872@2|Bacteria,1PW6G@1224|Proteobacteria,2WBRH@28216|Betaproteobacteria,44WKF@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0235 family	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
REGS1_k127_652413_7	395494.Galf_2266	6.034e-193	611.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1Q94S@1224|Proteobacteria,2VIVY@28216|Betaproteobacteria,44W9I@713636|Nitrosomonadales	28216|Betaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	-	-	-	-	-	-	-	-	-	-	LRR_4,LRR_8,Pkinase,Pkinase_Tyr
REGS1_k127_652413_0	580332.Slit_2833	0.0	1451.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,2VJ57@28216|Betaproteobacteria,44V1E@713636|Nitrosomonadales	28216|Betaproteobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
REGS1_k127_652413_10	1485544.JQKP01000002_gene1446	1.016e-123	399.0	COG1611@1|root,COG1611@2|Bacteria,1MU6N@1224|Proteobacteria,2VK4I@28216|Betaproteobacteria,44VF9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Possible lysine decarboxylase	yvdD_2	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
REGS1_k127_652413_12	580332.Slit_2975	2.022e-103	344.0	COG4395@1|root,COG4395@2|Bacteria,1NSUG@1224|Proteobacteria,2VNS7@28216|Betaproteobacteria,44VJS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM import inner membrane translocase subunit Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
REGS1_k127_652413_13	1485544.JQKP01000001_gene918	4.884e-65	229.0	COG3165@1|root,COG3165@2|Bacteria,1N314@1224|Proteobacteria,2VU2B@28216|Betaproteobacteria,44WEV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K03690	-	-	-	-	ko00000	-	-	-	SCP2
REGS1_k127_652413_6	243365.CV_0991	5.808e-194	617.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,2VJ07@28216|Betaproteobacteria,2KPMS@206351|Neisseriales	206351|Neisseriales	H	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis	ubiB	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
REGS1_k127_652413_18	1122621.ATZA01000017_gene3900	7.622e-13	81.0	2C4G8@1|root,33PXF@2|Bacteria,4P1CY@976|Bacteroidetes,1IVCF@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_652413_3	265072.Mfla_2741	3.72e-313	967.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,2VHVY@28216|Betaproteobacteria,2KKU5@206350|Nitrosomonadales	206350|Nitrosomonadales	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
REGS1_k127_652413_4	580332.Slit_2979	5.832e-234	730.0	COG1207@1|root,COG1207@2|Bacteria,1MUPH@1224|Proteobacteria,2VH54@28216|Betaproteobacteria,44V20@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	-	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,NTP_transf_3
REGS1_k127_652413_14	1485544.JQKP01000012_gene2161	2.021e-61	214.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,2VR2R@28216|Betaproteobacteria,44VV1@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
REGS1_k127_652413_5	1485544.JQKP01000012_gene2162	2.956e-231	717.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,2VHDZ@28216|Betaproteobacteria,44V86@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
REGS1_k127_6614089_0	1485544.JQKP01000004_gene461	1.112e-272	841.0	COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,44VED@713636|Nitrosomonadales	28216|Betaproteobacteria	E	PFAM Orn Lys Arg decarboxylase major region	adi	-	4.1.1.19	ko:K01584	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N
REGS1_k127_6614089_1	1163617.SCD_n01898	1.642e-108	375.0	COG2199@1|root,COG2202@1|root,COG2199@2|Bacteria,COG2202@2|Bacteria,1NWNJ@1224|Proteobacteria,2WHI5@28216|Betaproteobacteria	28216|Betaproteobacteria	T	PAS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,PAS_9
REGS1_k127_6614089_3	580332.Slit_2522	4.609e-74	252.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2VSH8@28216|Betaproteobacteria,44VR3@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
REGS1_k127_6614089_2	580332.Slit_2520	4.647e-100	327.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,2VIIR@28216|Betaproteobacteria,44VCH@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
REGS1_k127_6782700_1	395494.Galf_0011	9.447e-299	931.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,2VMUG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the peptidase S41A family	prc	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
REGS1_k127_6782700_4	1410620.SHLA_63c000100	1.471e-70	243.0	COG4627@1|root,COG4627@2|Bacteria,1RBR3@1224|Proteobacteria,2U9VX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_6782700_0	580332.Slit_2203	0.0	1569.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,2VHYF@28216|Betaproteobacteria,44VJZ@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
REGS1_k127_6782700_3	1485544.JQKP01000017_gene628	2.395e-110	381.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,2VHSU@28216|Betaproteobacteria,44V18@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
REGS1_k127_6782700_2	555778.Hneap_1707	5.429e-132	443.0	COG1404@1|root,COG1404@2|Bacteria,1MU3S@1224|Proteobacteria,1RSP9@1236|Gammaproteobacteria,1WZCK@135613|Chromatiales	135613|Chromatiales	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8
REGS1_k127_6782700_6	62928.azo3118	1.515e-10	61.0	COG0720@1|root,COG0720@2|Bacteria,1RETG@1224|Proteobacteria,2VRBN@28216|Betaproteobacteria,2KW9I@206389|Rhodocyclales	206389|Rhodocyclales	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
REGS1_k127_6802995_9	583345.Mmol_0121	5.703e-43	158.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,2VH3Z@28216|Betaproteobacteria	28216|Betaproteobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
REGS1_k127_6802995_3	697282.Mettu_0616	1.125e-102	348.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
REGS1_k127_6802995_13	1499967.BAYZ01000145_gene6206	1.971e-33	132.0	COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
REGS1_k127_6802995_10	397948.Cmaq_0517	2.141e-39	154.0	COG0801@1|root,arCOG07203@2157|Archaea	2157|Archaea	H	Dihydroneopterin aldolase	-	-	-	-	-	-	-	-	-	-	-	-	FolB,HPPK
REGS1_k127_6802995_11	243159.AFE_1839	1.599e-38	149.0	COG3324@1|root,COG3324@2|Bacteria,1N7Q5@1224|Proteobacteria,1SB3Z@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	related to lactoylglutathione lyase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
REGS1_k127_6802995_1	395494.Galf_1110	0.0	1101.0	COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,2VHFD@28216|Betaproteobacteria,44V7H@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Threonyl and Alanyl tRNA synthetase second additional domain	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
REGS1_k127_6802995_4	580332.Slit_1736	3.471e-95	314.0	COG0290@1|root,COG0290@2|Bacteria,1RDD2@1224|Proteobacteria,2VQ19@28216|Betaproteobacteria,44VQU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
REGS1_k127_6802995_14	261292.Nit79A3_0829	4.672e-27	113.0	COG0291@1|root,COG0291@2|Bacteria,1N6V4@1224|Proteobacteria,2VVS9@28216|Betaproteobacteria,373NU@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
REGS1_k127_6802995_5	580332.Slit_1734	2.97e-60	209.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,2VRWF@28216|Betaproteobacteria,44VWN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
REGS1_k127_6802995_2	580332.Slit_1733	4.148e-200	626.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,2VIM9@28216|Betaproteobacteria,44VDW@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
REGS1_k127_6802995_0	580332.Slit_1731	0.0	1205.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1MWKS@1224|Proteobacteria,2VHR1@28216|Betaproteobacteria,44V1R@713636|Nitrosomonadales	28216|Betaproteobacteria	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
REGS1_k127_6802995_6	580332.Slit_1730	1.282e-52	188.0	COG0776@1|root,COG0776@2|Bacteria,1RH5Z@1224|Proteobacteria,2VT12@28216|Betaproteobacteria,44VWJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control	himA	-	-	ko:K04764	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_6802995_8	1218075.BAYA01000001_gene472	1.447e-46	170.0	COG0789@1|root,COG0789@2|Bacteria,1RGYB@1224|Proteobacteria,2VSDF@28216|Betaproteobacteria,1K7KJ@119060|Burkholderiaceae	28216|Betaproteobacteria	K	PFAM regulatory protein, MerR	ycgE	-	-	-	-	-	-	-	-	-	-	-	MerR_1
REGS1_k127_6802995_16	59538.XP_005979423.1	3.517e-06	51.0	COG0277@1|root,KOG1231@2759|Eukaryota,38FXH@33154|Opisthokonta,3BEEV@33208|Metazoa,3CRTP@33213|Bilateria,4801S@7711|Chordata,492UT@7742|Vertebrata,3JDRF@40674|Mammalia,4J43Y@91561|Cetartiodactyla	33208|Metazoa	C	dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4,Fer4_8
REGS1_k127_6802995_7	1454004.AW11_03578	1.928e-49	188.0	COG0739@1|root,COG0739@2|Bacteria,1N19D@1224|Proteobacteria	1224|Proteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124,Peptidase_M23
REGS1_k127_6802995_12	1005048.CFU_1826	7.957e-38	144.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VHM2@28216|Betaproteobacteria,473I4@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
REGS1_k127_6818232_1	580332.Slit_0343	2.005e-231	718.0	COG1807@1|root,COG1807@2|Bacteria,1PUE3@1224|Proteobacteria,2VHPU@28216|Betaproteobacteria,44VIR@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
REGS1_k127_6818232_0	580332.Slit_0344	3.709e-248	773.0	COG4784@1|root,COG4784@2|Bacteria,1QTT7@1224|Proteobacteria,2WHEI@28216|Betaproteobacteria,44UZ2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_6818232_3	580332.Slit_0345	7.774e-38	142.0	COG0254@1|root,COG0254@2|Bacteria,1MZ69@1224|Proteobacteria,2VW5V@28216|Betaproteobacteria,44W17@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L31	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
REGS1_k127_6818232_2	580332.Slit_0346	1.305e-66	228.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,2VUVV@28216|Betaproteobacteria,44VWI@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	-	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
REGS1_k127_6857354_16	204773.HEAR0933	6.199e-89	310.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VH9K@28216|Betaproteobacteria,474DV@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
REGS1_k127_6857354_3	1238182.C882_0210	5.469e-230	731.0	COG0577@1|root,COG1136@1|root,COG0577@2|Bacteria,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,2TS3W@28211|Alphaproteobacteria,2JQ1G@204441|Rhodospirillales	204441|Rhodospirillales	V	membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K05685	ko02010,map02010	M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
REGS1_k127_6857354_12	1175306.GWL_28500	4.308e-93	323.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VJTV@28216|Betaproteobacteria,47284@75682|Oxalobacteraceae	28216|Betaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_6857354_17	626887.J057_17725	6.4e-86	295.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku,Rho_N
REGS1_k127_6857354_14	1166948.JPZL01000001_gene3114	7.772e-90	305.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1SBKT@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
REGS1_k127_6857354_1	1166948.JPZL01000001_gene3112	1.187e-291	918.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,1RQ06@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	DNA ligase	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
REGS1_k127_6857354_4	686340.Metal_3888	4.59e-218	682.0	COG2081@1|root,COG2081@2|Bacteria,1MUGC@1224|Proteobacteria,1RRAS@1236|Gammaproteobacteria,1XEII@135618|Methylococcales	135618|Methylococcales	S	flavoprotein, PP_4765 family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
REGS1_k127_6857354_18	580332.Slit_1055	6.568e-79	268.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,2VRHU@28216|Betaproteobacteria,44WDJ@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
REGS1_k127_6857354_2	580332.Slit_0252	1.341e-276	865.0	COG2114@1|root,COG4252@1|root,COG2114@2|Bacteria,COG4252@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	CHASE2,Guanylate_cyc
REGS1_k127_6857354_0	580332.Slit_0253	0.0	1269.0	COG0457@1|root,COG1305@1|root,COG3391@1|root,COG4733@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,COG3391@2|Bacteria,COG4733@2|Bacteria,1R42S@1224|Proteobacteria	1224|Proteobacteria	E	fibronectin type III domain protein	-	-	-	ko:K06882	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_6857354_22	887062.HGR_15374	2.285e-24	108.0	COG1729@1|root,COG1729@2|Bacteria,1P69R@1224|Proteobacteria,2W622@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6857354_7	1485544.JQKP01000007_gene2032	1.762e-191	629.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_3,PAS_4,PAS_8,PAS_9
REGS1_k127_6857354_20	580332.Slit_0995	4.966e-47	172.0	COG0640@1|root,COG0640@2|Bacteria,1MZAU@1224|Proteobacteria,2VTXZ@28216|Betaproteobacteria,44W07@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20
REGS1_k127_6857354_13	580332.Slit_0996	1.015e-90	300.0	COG0394@1|root,COG0394@2|Bacteria,1MWYQ@1224|Proteobacteria,2VI3V@28216|Betaproteobacteria,44VDD@713636|Nitrosomonadales	28216|Betaproteobacteria	T	SMART Protein-tyrosine phosphatase, low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
REGS1_k127_6857354_8	580332.Slit_0997	1.491e-185	583.0	COG0798@1|root,COG0798@2|Bacteria,1MUXY@1224|Proteobacteria,2VHWA@28216|Betaproteobacteria,44VD8@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Sodium Bile acid symporter family	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
REGS1_k127_6857354_19	1121035.AUCH01000007_gene451	1.179e-61	216.0	COG2110@1|root,COG2110@2|Bacteria	2|Bacteria	P	phosphatase homologous to the C-terminal domain of histone macroH2A1	tfaE	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Caudo_TAP,Macro
REGS1_k127_6857354_11	1121035.AUCH01000004_gene368	5.551e-104	346.0	COG1397@1|root,COG1397@2|Bacteria,1PRWK@1224|Proteobacteria,2WA1G@28216|Betaproteobacteria,2KZF1@206389|Rhodocyclales	206389|Rhodocyclales	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ADP_ribosyl_GH
REGS1_k127_6857354_15	114615.BRADO3028	1.068e-89	302.0	COG1051@1|root,COG1051@2|Bacteria,1QTT4@1224|Proteobacteria,2TWST@28211|Alphaproteobacteria,3JUB4@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	F	hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
REGS1_k127_6857354_9	1245469.S58_45750	2.064e-129	422.0	COG0330@1|root,COG0330@2|Bacteria,1PEW9@1224|Proteobacteria,2TVA5@28211|Alphaproteobacteria,3JWCI@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	SPFH domain / Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_6857354_10	189753.AXAS01000002_gene5162	1.003e-115	380.0	COG0061@1|root,COG0061@2|Bacteria,1NBI3@1224|Proteobacteria,2TUCV@28211|Alphaproteobacteria,3JTFG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
REGS1_k127_6857354_5	316067.Geob_3570	1.342e-213	678.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42P4F@68525|delta/epsilon subdivisions,2WJVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
REGS1_k127_6857354_21	497965.Cyan7822_3572	2.1e-29	123.0	COG4251@1|root,COG4251@2|Bacteria,1G83Y@1117|Cyanobacteria	1117|Cyanobacteria	T	PFAM KaiB domain	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
REGS1_k127_6857354_6	580332.Slit_0879	1.819e-210	676.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W76@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS_3,PAS_9
REGS1_k127_6860746_30	580332.Slit_1755	5.584e-38	145.0	COG2933@1|root,COG2933@2|Bacteria,1MWBM@1224|Proteobacteria,2VJ71@28216|Betaproteobacteria,44VBJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	FtsJ-like methyltransferase	rlmM	-	2.1.1.186	ko:K06968	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
REGS1_k127_6860746_17	580332.Slit_1754	4.016e-101	332.0	COG0546@1|root,COG0546@2|Bacteria,1RDA7@1224|Proteobacteria,2VIZ2@28216|Betaproteobacteria,44UYP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1	ppaX	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_6860746_10	580332.Slit_1753	5.159e-150	479.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,2VH94@28216|Betaproteobacteria,44V82@713636|Nitrosomonadales	28216|Betaproteobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
REGS1_k127_6860746_37	1318628.MARLIPOL_02385	0.000276	53.0	2EMFB@1|root,33F44@2|Bacteria,1NH7D@1224|Proteobacteria,1SGY2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2059)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2059
REGS1_k127_6860746_0	580332.Slit_1752	1.896e-282	886.0	COG1331@1|root,COG1331@2|Bacteria,1MUUT@1224|Proteobacteria,2VKKI@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
REGS1_k127_6860746_12	580332.Slit_1656	1.14e-131	426.0	COG0412@1|root,COG0412@2|Bacteria,1NKIB@1224|Proteobacteria,2VTN7@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
REGS1_k127_6860746_13	580332.Slit_2147	2.907e-121	402.0	COG0739@1|root,COG0739@2|Bacteria,1MY2X@1224|Proteobacteria,2VI8F@28216|Betaproteobacteria	28216|Betaproteobacteria	M	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
REGS1_k127_6860746_5	580332.Slit_1655	1.422e-208	654.0	COG1322@1|root,COG1322@2|Bacteria,1MWHV@1224|Proteobacteria,2VJVZ@28216|Betaproteobacteria,44W4C@713636|Nitrosomonadales	28216|Betaproteobacteria	S	RmuC family	rmuC	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
REGS1_k127_6860746_33	395494.Galf_1257	1.422e-28	123.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1MYBP@1224|Proteobacteria,2VR0Y@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the ompA family	yiaD_1	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	Gly-zipper_Omp,Gly-zipper_YMGG,OmpA,Rick_17kDa_Anti
REGS1_k127_6860746_9	1485544.JQKP01000013_gene1787	4.945e-159	503.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,2VI8C@28216|Betaproteobacteria,44V2A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
REGS1_k127_6860746_22	1163617.SCD_n00224	3.428e-71	241.0	COG0607@1|root,COG0607@2|Bacteria,1REHH@1224|Proteobacteria,2VTFS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	rhodanese-related sulfurtransferase	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
REGS1_k127_6860746_34	1163617.SCD_n00799	2.977e-27	112.0	COG0425@1|root,COG0425@2|Bacteria,1MZA5@1224|Proteobacteria,2VVW5@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	TusA
REGS1_k127_6860746_11	312153.Pnuc_1168	2.866e-137	454.0	COG2194@1|root,COG2194@2|Bacteria,1MWJY@1224|Proteobacteria,2VK3V@28216|Betaproteobacteria,1K52W@119060|Burkholderiaceae	28216|Betaproteobacteria	S	cellulose synthase	-	-	-	-	-	-	-	-	-	-	-	-	CBP_BcsG
REGS1_k127_6860746_14	388051.AUFE01000016_gene5856	5.074e-112	394.0	COG0457@1|root,COG4783@1|root,COG0457@2|Bacteria,COG4783@2|Bacteria,1MVB8@1224|Proteobacteria,2VHKT@28216|Betaproteobacteria,1K2RS@119060|Burkholderiaceae	28216|Betaproteobacteria	D	cellulose synthase operon C domain protein	-	-	-	ko:K20543	-	-	-	-	ko00000,ko02000	1.B.55.3	-	-	BCSC_C,TPR_16,TPR_19,TPR_8
REGS1_k127_6860746_8	582744.Msip34_0040	8.259e-171	563.0	COG3266@1|root,COG3266@2|Bacteria,1NAC9@1224|Proteobacteria	1224|Proteobacteria	S	cellulose synthase	celB	-	-	ko:K20541	-	-	-	-	ko00000,ko02000	4.D.3.1.6	-	-	BcsB
REGS1_k127_6860746_1	312153.Pnuc_1171	2.267e-275	875.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,2VHGG@28216|Betaproteobacteria,1K1RI@119060|Burkholderiaceae	28216|Betaproteobacteria	M	cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Glycos_transf_2,PilZ
REGS1_k127_6860746_29	1348114.OM33_16920	2.913e-47	190.0	COG2114@1|root,COG2114@2|Bacteria,1NC69@1224|Proteobacteria	1224|Proteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,SnoaL_3
REGS1_k127_6860746_23	1123261.AXDW01000001_gene1371	1.328e-70	261.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,1RR36@1236|Gammaproteobacteria,1X6T3@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,HAMP,Pkinase,sCache_3_2
REGS1_k127_6860746_16	582744.Msip34_0042	6.297e-102	343.0	COG3405@1|root,COG3405@2|Bacteria,1MW17@1224|Proteobacteria,2VHE2@28216|Betaproteobacteria,2KP27@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Glycosyl hydrolases family 8	-	-	3.2.1.4	ko:K20542	-	-	-	-	ko00000,ko01000	-	GH8	-	Glyco_hydro_8
REGS1_k127_6860746_6	580332.Slit_0954	1.729e-190	599.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,2VJRR@28216|Betaproteobacteria,44VAS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
REGS1_k127_6860746_21	1485544.JQKP01000007_gene1954	2.544e-73	249.0	COG1051@1|root,COG1051@2|Bacteria,1N03W@1224|Proteobacteria,2VRC0@28216|Betaproteobacteria,44VT0@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the Nudix hydrolase family. NudJ subfamily	nudJ	-	-	-	-	-	-	-	-	-	-	-	NUDIX
REGS1_k127_6860746_32	1485544.JQKP01000002_gene1488	7.671e-29	122.0	COG2847@1|root,COG2847@2|Bacteria,1PWY4@1224|Proteobacteria,2WCG0@28216|Betaproteobacteria,44W0E@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
REGS1_k127_6860746_35	580332.Slit_0733	9.833e-19	93.0	COG2847@1|root,COG2847@2|Bacteria	2|Bacteria	P	Copper chaperone PCu(A)C	-	-	-	ko:K09796	-	-	-	-	ko00000,ko03110	-	-	-	PCuAC
REGS1_k127_6860746_7	1485544.JQKP01000001_gene1032	3.612e-171	539.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2VIIY@28216|Betaproteobacteria,44V2H@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
REGS1_k127_6860746_18	580332.Slit_0736	5.187e-99	326.0	COG0637@1|root,COG0637@2|Bacteria,1QTWD@1224|Proteobacteria,2VNTW@28216|Betaproteobacteria,44UZ1@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 3	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
REGS1_k127_6860746_19	1485544.JQKP01000001_gene1034	1.766e-92	308.0	COG1309@1|root,COG1309@2|Bacteria,1MWF7@1224|Proteobacteria,2VQ4C@28216|Betaproteobacteria,44WBD@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory proteins, tetR family	slmA	-	-	ko:K05501	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	TetR_N
REGS1_k127_6860746_4	580332.Slit_0738	1.284e-213	667.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VZA1@28216|Betaproteobacteria,44V5H@713636|Nitrosomonadales	28216|Betaproteobacteria	E	DAHP synthetase I family	-	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
REGS1_k127_6860746_15	580332.Slit_2133	2.886e-106	350.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,2VR7K@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_6860746_28	1485544.JQKP01000001_gene1047	1.813e-57	203.0	2AFCJ@1|root,315C6@2|Bacteria,1RH66@1224|Proteobacteria,2VSTN@28216|Betaproteobacteria,44VU7@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF1841)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1841
REGS1_k127_6860746_20	580332.Slit_1999	2.27e-73	256.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,2VJZP@28216|Betaproteobacteria,44VIY@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
REGS1_k127_6860746_31	748280.NH8B_1713	1.277e-36	140.0	COG2350@1|root,COG2350@2|Bacteria,1MZ9Z@1224|Proteobacteria,2VUM7@28216|Betaproteobacteria,2KRJ4@206351|Neisseriales	206351|Neisseriales	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
REGS1_k127_6860746_27	1163617.SCD_n01474	5.664e-58	209.0	COG2917@1|root,COG2917@2|Bacteria,1NWIZ@1224|Proteobacteria,2VRHB@28216|Betaproteobacteria	28216|Betaproteobacteria	D	probably involved in intracellular septation	ispZ	-	-	ko:K06190	-	-	-	-	ko00000	-	-	-	IspA
REGS1_k127_6860746_26	580332.Slit_1996	2.53e-66	228.0	COG0229@1|root,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,2VSHQ@28216|Betaproteobacteria,44VWV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	SelR
REGS1_k127_6860746_3	1485544.JQKP01000003_gene213	3.558e-253	787.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,2VH4P@28216|Betaproteobacteria,44VHZ@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
REGS1_k127_6860746_24	1485544.JQKP01000003_gene212	5.812e-70	243.0	COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,2VR4P@28216|Betaproteobacteria,44VTM@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	bcp	GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
REGS1_k127_6860746_2	580332.Slit_0953	2.497e-254	789.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,2VI2T@28216|Betaproteobacteria,44VN3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ASL_C,Lyase_1
REGS1_k127_6860746_25	1121035.AUCH01000014_gene2354	8.378e-70	249.0	COG0705@1|root,COG0705@2|Bacteria,1PRTS@1224|Proteobacteria,2VM82@28216|Betaproteobacteria,2KXF8@206389|Rhodocyclales	206389|Rhodocyclales	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
REGS1_k127_6939341_7	580332.Slit_2733	4.204e-90	297.0	COG0120@1|root,COG0120@2|Bacteria,1MVGR@1224|Proteobacteria,2VH27@28216|Betaproteobacteria,44VEN@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A,Sugar-bind
REGS1_k127_6939341_5	1485544.JQKP01000001_gene933	3.885e-130	417.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,2VI2C@28216|Betaproteobacteria,44UZR@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
REGS1_k127_6939341_1	580332.Slit_2731	2.081e-244	762.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,2VI1K@28216|Betaproteobacteria,44V08@713636|Nitrosomonadales	28216|Betaproteobacteria	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
REGS1_k127_6939341_8	228410.NE1318	4.346e-72	253.0	COG0741@1|root,COG0741@2|Bacteria,1R666@1224|Proteobacteria,2VHI4@28216|Betaproteobacteria,37307@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT
REGS1_k127_6939341_0	580332.Slit_0746	1.024e-245	764.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,44VAV@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
REGS1_k127_6939341_9	1288494.EBAPG3_4100	2.725e-62	215.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,2VGZ9@28216|Betaproteobacteria,371UB@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
REGS1_k127_6939341_4	580332.Slit_1782	1.404e-145	466.0	COG0784@1|root,COG3437@1|root,COG0784@2|Bacteria,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,HATPase_c,HisKA,Response_reg
REGS1_k127_6939341_3	580332.Slit_1783	1.086e-192	613.0	COG0517@1|root,COG4191@1|root,COG0517@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	CBS,HATPase_c,HisKA,Response_reg,dCache_1
REGS1_k127_6939341_2	1485544.JQKP01000001_gene1287	1.569e-240	758.0	COG0517@1|root,COG2199@1|root,COG2200@1|root,COG0517@2|Bacteria,COG2199@2|Bacteria,COG2200@2|Bacteria,1MVJY@1224|Proteobacteria,2VI53@28216|Betaproteobacteria,44VCU@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	yjcC	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
REGS1_k127_6939341_6	580332.Slit_2472	1.169e-93	313.0	COG1434@1|root,COG1434@2|Bacteria,1MVW8@1224|Proteobacteria,2VSTA@28216|Betaproteobacteria,44W6B@713636|Nitrosomonadales	28216|Betaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
REGS1_k127_69468_2	1217652.F954_01859	2.977e-17	87.0	2BHX2@1|root,32C14@2|Bacteria,1QPWU@1224|Proteobacteria,1TNNX@1236|Gammaproteobacteria,3NQZ4@468|Moraxellaceae	1236|Gammaproteobacteria	S	Super-infection exclusion protein B	-	-	-	-	-	-	-	-	-	-	-	-	SieB
REGS1_k127_69468_0	522306.CAP2UW1_3972	7.591e-160	512.0	COG0517@1|root,COG0517@2|Bacteria,1MXI6@1224|Proteobacteria,2VJ2W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
REGS1_k127_69468_1	522306.CAP2UW1_3973	2.181e-118	387.0	COG4974@1|root,COG4974@2|Bacteria,1MVAN@1224|Proteobacteria,2VHUC@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
REGS1_k127_7084048_4	1485544.JQKP01000001_gene1107	1.503e-34	132.0	COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,2VJ7K@28216|Betaproteobacteria,44V4T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
REGS1_k127_7084048_1	1144325.PMI22_04840	4.321e-146	469.0	COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
REGS1_k127_7084048_2	871968.DESME_14335	1.59e-94	319.0	COG0451@1|root,COG0451@2|Bacteria,1UYQY@1239|Firmicutes,248H3@186801|Clostridia	186801|Clostridia	GM	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
REGS1_k127_7084048_0	580332.Slit_0317	5.362e-209	678.0	COG1807@1|root,COG1807@2|Bacteria,1R7N1@1224|Proteobacteria,2VPJR@28216|Betaproteobacteria,44V9W@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM glycosyl transferase family 39	-	-	-	-	-	-	-	-	-	-	-	-	PMT
REGS1_k127_7084048_3	1485544.JQKP01000011_gene762	3.789e-48	176.0	COG4692@1|root,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2VMXN@28216|Betaproteobacteria,44VCC@713636|Nitrosomonadales	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
REGS1_k127_712810_5	395494.Galf_0975	5.665e-07	55.0	COG5001@1|root,COG5002@1|root,COG5001@2|Bacteria,COG5002@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W7B@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S)	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,NIT,PAS,PAS_4,PAS_9,Response_reg
REGS1_k127_712810_3	622637.KE124774_gene1367	2.974e-48	175.0	2B9KW@1|root,322Z5@2|Bacteria,1RJJB@1224|Proteobacteria,2UAVD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_712810_2	1214065.BAGV01000093_gene219	3.008e-61	223.0	COG3863@1|root,COG3863@2|Bacteria,1RBGX@1224|Proteobacteria,1S01D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	yiiX	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
REGS1_k127_712810_0	595537.Varpa_3800	1.257e-95	317.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria,4ADRK@80864|Comamonadaceae	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_712810_4	580332.Slit_0930	4.936e-39	150.0	2E5Q2@1|root,330EP@2|Bacteria,1NCEJ@1224|Proteobacteria,2VVYT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3106
REGS1_k127_712810_1	580332.Slit_0929	1.385e-91	304.0	COG1595@1|root,COG1595@2|Bacteria,1R3SM@1224|Proteobacteria,2VS23@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
REGS1_k127_7151712_12	1121035.AUCH01000014_gene2354	1.295e-43	168.0	COG0705@1|root,COG0705@2|Bacteria,1PRTS@1224|Proteobacteria,2VM82@28216|Betaproteobacteria,2KXF8@206389|Rhodocyclales	206389|Rhodocyclales	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
REGS1_k127_7151712_0	580332.Slit_1396	6.755e-310	967.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,2VHKP@28216|Betaproteobacteria,44UYC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM DNA internalization-related competence protein ComEC Rec2	comA	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
REGS1_k127_7151712_6	1123504.JQKD01000036_gene3137	1.782e-171	551.0	COG0425@1|root,COG0425@2|Bacteria,1R8DP@1224|Proteobacteria,2WFJB@28216|Betaproteobacteria,4AD5S@80864|Comamonadaceae	28216|Betaproteobacteria	O	Belongs to the sulfur carrier protein TusA family	-	-	-	-	-	-	-	-	-	-	-	-	AurF
REGS1_k127_7151712_8	261292.Nit79A3_1297	5.237e-101	337.0	COG3221@1|root,COG3221@2|Bacteria,1N92V@1224|Proteobacteria,2WBUH@28216|Betaproteobacteria,373TX@32003|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter, phosphonate, periplasmic substrate-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Phosphonate-bd
REGS1_k127_7151712_7	887062.HGR_05206	2.288e-153	492.0	COG1960@1|root,COG1960@2|Bacteria,1MUDR@1224|Proteobacteria,2VHT0@28216|Betaproteobacteria,4AD3F@80864|Comamonadaceae	28216|Betaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
REGS1_k127_7151712_4	172045.KS04_13880	1.618e-218	698.0	COG1479@1|root,COG1479@2|Bacteria,4NP7Q@976|Bacteroidetes,1I27A@117743|Flavobacteriia,34S00@308865|Elizabethkingia	976|Bacteroidetes	S	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
REGS1_k127_7151712_15	56107.Cylst_2883	6.194e-07	62.0	COG3831@1|root,COG3831@2|Bacteria,1G6I3@1117|Cyanobacteria,1HRTN@1161|Nostocales	1117|Cyanobacteria	S	Domain of unknown function (DUF1963)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1963,WGR
REGS1_k127_7151712_10	391735.Veis_2985	5.055e-51	198.0	COG3103@1|root,COG3103@2|Bacteria,1MVX1@1224|Proteobacteria,2VKXR@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7151712_9	391735.Veis_2986	4.009e-72	251.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,2VJ61@28216|Betaproteobacteria,4AAUA@80864|Comamonadaceae	28216|Betaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
REGS1_k127_7151712_2	470.IX87_15175	1.074e-235	752.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,1RPIP@1236|Gammaproteobacteria,3NM9J@468|Moraxellaceae	1236|Gammaproteobacteria	GM	Outer membrane lipoprotein-sorting protein	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	LolA_like,MMPL,Polyketide_cyc2
REGS1_k127_7151712_14	1220535.IMCC14465_09970	6.566e-17	88.0	COG1309@1|root,COG1309@2|Bacteria,1N71J@1224|Proteobacteria,2UHJN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
REGS1_k127_7151712_3	580332.Slit_1660	7.872e-220	695.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VC4@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM DEAD DEAH box helicase domain protein	rhlE1	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
REGS1_k127_7151712_1	580332.Slit_2108	1.7e-275	852.0	COG0034@1|root,COG0034@2|Bacteria,1MU0V@1224|Proteobacteria,2VJM1@28216|Betaproteobacteria,44VHT@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
REGS1_k127_7151712_11	580332.Slit_2109	6.254e-44	165.0	COG1286@1|root,COG1286@2|Bacteria,1NF4G@1224|Proteobacteria,2VUM6@28216|Betaproteobacteria,44W0T@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Colicin V production protein	cvpA	-	-	ko:K03558	-	-	-	-	ko00000	-	-	-	Colicin_V
REGS1_k127_7151712_13	1485544.JQKP01000005_gene362	6.063e-37	147.0	COG3147@1|root,COG3147@2|Bacteria,1R7IV@1224|Proteobacteria,2VPE1@28216|Betaproteobacteria,44VYQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sporulation related domain	dedD	-	-	ko:K03749	-	-	-	-	ko00000	-	-	-	SPOR
REGS1_k127_7151712_5	580332.Slit_2111	2.414e-181	576.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,2VI0H@28216|Betaproteobacteria,44V34@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM Mur ligase middle domain protein	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
REGS1_k127_7236740_0	1121035.AUCH01000007_gene585	9.503e-73	250.0	COG0542@1|root,COG0542@2|Bacteria,1MWQQ@1224|Proteobacteria,2VH2V@28216|Betaproteobacteria,2KVXD@206389|Rhodocyclales	206389|Rhodocyclales	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_2,ClpB_D2-small
REGS1_k127_7236740_1	1121035.AUCH01000007_gene586	5.048e-67	246.0	2ES6E@1|root,32KS5@2|Bacteria,1NXC7@1224|Proteobacteria,2W387@28216|Betaproteobacteria,2KYZI@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7236740_2	1150626.PHAMO_10203	1.18e-58	205.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2TSN3@28211|Alphaproteobacteria,2JPTI@204441|Rhodospirillales	204441|Rhodospirillales	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_7290639_2	580332.Slit_2736	5.173e-60	209.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,44VSX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
REGS1_k127_7290639_3	1485544.JQKP01000012_gene2111	1.324e-51	189.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,2VU5R@28216|Betaproteobacteria,44VW8@713636|Nitrosomonadales	28216|Betaproteobacteria	L	PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
REGS1_k127_7290639_1	580332.Slit_2734	2.142e-158	505.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,2VIHD@28216|Betaproteobacteria,44V19@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_7290639_4	580332.Slit_1577	2.008e-19	97.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K03286,ko:K12976,ko:K16079	-	-	-	-	ko00000,ko01000,ko01005,ko02000	1.B.4.2.1,1.B.6	-	-	CBP_BcsS,OMP_b-brl
REGS1_k127_7290639_0	580332.Slit_0739	3.784e-292	902.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,2VI4G@28216|Betaproteobacteria,44V3P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
REGS1_k127_7302363_33	640081.Dsui_2423	2.225e-08	55.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,2VH2W@28216|Betaproteobacteria,2KUXJ@206389|Rhodocyclales	206389|Rhodocyclales	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
REGS1_k127_7302363_22	857087.Metme_2463	1.421e-104	349.0	COG4714@1|root,COG4714@2|Bacteria,1N40I@1224|Proteobacteria,1S1R3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	membrane-anchored protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2167
REGS1_k127_7302363_21	857087.Metme_2221	4.824e-107	351.0	COG1994@1|root,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,1RQY8@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	COG1994 Zn-dependent proteases	-	-	-	-	-	-	-	-	-	-	-	-	DUF3267,Peptidase_M50
REGS1_k127_7302363_20	580332.Slit_1241	4.265e-112	371.0	COG3735@1|root,COG3735@2|Bacteria,1MVCW@1224|Proteobacteria,2VQAJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM GumN family protein	-	-	-	ko:K09973	-	-	-	-	ko00000	-	-	-	TraB
REGS1_k127_7302363_14	395494.Galf_2264	2.205e-135	434.0	COG1723@1|root,COG1723@2|Bacteria,1MWYM@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Uncharacterised ACR, YagE family COG1723	-	-	-	-	-	-	-	-	-	-	-	-	DUF155
REGS1_k127_7302363_15	395494.Galf_2546	6.782e-134	432.0	COG1161@1|root,COG1161@2|Bacteria,1MV5H@1224|Proteobacteria,2VHAG@28216|Betaproteobacteria,44VBP@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
REGS1_k127_7302363_23	580332.Slit_1234	5.244e-95	317.0	COG2981@1|root,COG2981@2|Bacteria,1Q181@1224|Proteobacteria,2VN29@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Etoposide-induced protein 2.4 (EI24)	-	-	-	-	-	-	-	-	-	-	-	-	EI24
REGS1_k127_7302363_17	1485544.JQKP01000007_gene1931	1.118e-124	402.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,2VI8V@28216|Betaproteobacteria,44V8R@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
REGS1_k127_7302363_13	580332.Slit_1650	2.734e-150	479.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,2VHSG@28216|Betaproteobacteria,44VIJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
REGS1_k127_7302363_18	395494.Galf_1791	3.558e-123	397.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,2VH8A@28216|Betaproteobacteria,44VAA@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
REGS1_k127_7302363_24	1485544.JQKP01000007_gene1934	5.867e-93	307.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,2VIUA@28216|Betaproteobacteria,44VJI@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
REGS1_k127_7302363_16	580332.Slit_1647	4.678e-127	410.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,2VH2E@28216|Betaproteobacteria,44V2T@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
REGS1_k127_7302363_26	395494.Galf_1788	3.249e-82	285.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,2VMM0@28216|Betaproteobacteria,44VDE@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
REGS1_k127_7302363_6	1485544.JQKP01000007_gene1937	4.249e-191	604.0	COG0743@1|root,COG0743@2|Bacteria,1MU4G@1224|Proteobacteria,2VHJY@28216|Betaproteobacteria,44V71@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
REGS1_k127_7302363_11	1485544.JQKP01000007_gene1938	1.331e-155	503.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2VHBW@28216|Betaproteobacteria,44V27@713636|Nitrosomonadales	28216|Betaproteobacteria	M	SMART PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
REGS1_k127_7302363_3	557598.LHK_02283	7.509e-235	749.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,2VHTX@28216|Betaproteobacteria,2KPPN@206351|Neisseriales	206351|Neisseriales	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
REGS1_k127_7302363_30	395494.Galf_1784	1.904e-49	190.0	COG2825@1|root,COG2825@2|Bacteria,1RD8X@1224|Proteobacteria,2VRZI@28216|Betaproteobacteria,44VX8@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM outer membrane chaperone Skp (OmpH)	ompH	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
REGS1_k127_7302363_12	580332.Slit_1641	2.631e-151	484.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,2VHJR@28216|Betaproteobacteria,44V3V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
REGS1_k127_7302363_28	1485544.JQKP01000007_gene1942	1.773e-76	258.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,2VRKQ@28216|Betaproteobacteria,44VTF@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
REGS1_k127_7302363_19	1163617.SCD_n01623	2.737e-116	379.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2VHDG@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
REGS1_k127_7302363_7	580332.Slit_1638	3.425e-186	588.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,2VIBP@28216|Betaproteobacteria,44VEA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
REGS1_k127_7302363_25	1485544.JQKP01000007_gene1945	1.073e-85	288.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2VQ06@28216|Betaproteobacteria,44VRD@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
REGS1_k127_7302363_27	582744.Msip34_1095	1.423e-81	278.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,2VRZM@28216|Betaproteobacteria,2KKG0@206350|Nitrosomonadales	206350|Nitrosomonadales	G	PFAM glucosamine galactosamine-6-phosphate isomerase	-	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
REGS1_k127_7302363_9	1163617.SCD_n01173	1.096e-159	509.0	COG1023@1|root,COG1023@2|Bacteria,1QU14@1224|Proteobacteria,2WH34@28216|Betaproteobacteria	28216|Betaproteobacteria	G	6-phosphogluconate dehydrogenase	-	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
REGS1_k127_7302363_2	1163617.SCD_n01174	1.519e-265	827.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,2VHS1@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
REGS1_k127_7302363_8	1395571.TMS3_0122845	1.612e-162	522.0	COG1055@1|root,COG1055@2|Bacteria,1MUH8@1224|Proteobacteria,1RPSM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	COG1055 Na H antiporter NhaD and related arsenite permeases	nhaD	-	-	-	-	-	-	-	-	-	-	-	CitMHS
REGS1_k127_7302363_0	1163617.SCD_n01944	0.0	1481.0	COG0045@1|root,COG0454@1|root,COG1042@1|root,COG0045@2|Bacteria,COG0456@2|Bacteria,COG1042@2|Bacteria,1MW98@1224|Proteobacteria,2VI9R@28216|Betaproteobacteria	28216|Betaproteobacteria	C	CoA-binding domain protein	yfiQ	-	-	ko:K09181	-	-	-	-	ko00000	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
REGS1_k127_7302363_10	1163617.SCD_n01943	2.049e-158	504.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,2VIK8@28216|Betaproteobacteria	28216|Betaproteobacteria	BQ	histone deacetylase	hda	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
REGS1_k127_7302363_32	395494.Galf_0527	3.76e-32	131.0	2B450@1|root,31WVI@2|Bacteria,1PWYX@1224|Proteobacteria,2WCGU@28216|Betaproteobacteria,44W24@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7302363_1	640081.Dsui_3260	0.0	1070.0	COG3808@1|root,COG3808@2|Bacteria,1MUQ3@1224|Proteobacteria,2VI3K@28216|Betaproteobacteria,2KV9E@206389|Rhodocyclales	206389|Rhodocyclales	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
REGS1_k127_7302363_4	580332.Slit_1358	3.456e-232	722.0	COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,2VK7J@28216|Betaproteobacteria,44WHF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
REGS1_k127_7302363_31	296591.Bpro_0609	1.878e-38	155.0	COG5430@1|root,COG5430@2|Bacteria,1PVUD@1224|Proteobacteria,2W3HC@28216|Betaproteobacteria,4AHZ2@80864|Comamonadaceae	28216|Betaproteobacteria	S	Spore Coat Protein U domain	-	-	-	-	-	-	-	-	-	-	-	-	SCPU
REGS1_k127_7302363_5	296591.Bpro_0610	4.261e-226	725.0	COG3188@1|root,COG3188@2|Bacteria,1MWV6@1224|Proteobacteria,2VIR3@28216|Betaproteobacteria,4AD84@80864|Comamonadaceae	28216|Betaproteobacteria	NU	Outer membrane usher protein	-	-	-	ko:K07347	ko05133,map05133	-	-	-	ko00000,ko00001,ko02000,ko02035,ko02044	1.B.11.3	-	-	PapC_C,Usher
REGS1_k127_7302363_29	296591.Bpro_0611	1.087e-61	221.0	COG3121@1|root,COG3121@2|Bacteria,1R4RJ@1224|Proteobacteria,2VXCK@28216|Betaproteobacteria,4AFJT@80864|Comamonadaceae	28216|Betaproteobacteria	M	Pili and flagellar-assembly chaperone, PapD N-terminal domain	papD	-	-	ko:K07346	-	-	-	-	ko00000,ko02035,ko02044,ko03110	-	-	-	PapD_N
REGS1_k127_7302363_34	296591.Bpro_0613	4.436e-06	49.0	28VC5@1|root,2ZHEW@2|Bacteria,1P4GX@1224|Proteobacteria,2W5EH@28216|Betaproteobacteria,4AIMX@80864|Comamonadaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7419651_0	580332.Slit_0798	0.0	1663.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,2VIJE@28216|Betaproteobacteria,44VAW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
REGS1_k127_7419651_8	580332.Slit_0796	4.146e-24	106.0	2ED0C@1|root,336XB@2|Bacteria,1ND2K@1224|Proteobacteria,2VXBS@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7419651_5	580332.Slit_0795	5.064e-36	141.0	2E2UU@1|root,32XWR@2|Bacteria,1N192@1224|Proteobacteria,2VUA1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7419651_1	1349767.GJA_3240	0.0	1063.0	COG0612@1|root,COG0612@2|Bacteria,1Q9S9@1224|Proteobacteria,2WBVP@28216|Betaproteobacteria,476J2@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	pqqL	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
REGS1_k127_7419651_4	580332.Slit_0794	5.607e-70	238.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2VR6I@28216|Betaproteobacteria,44VXK@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
REGS1_k127_7419651_2	580332.Slit_0793	2.756e-172	544.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,2VHG6@28216|Betaproteobacteria,44V49@713636|Nitrosomonadales	28216|Betaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
REGS1_k127_7419651_6	1485544.JQKP01000001_gene1134	9.442e-36	136.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,2VGZH@28216|Betaproteobacteria,44VAX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
REGS1_k127_7438461_2	580332.Slit_2428	1.097e-140	449.0	COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,2VKWZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Dehydrogenase	sndH	-	-	-	-	-	-	-	-	-	-	-	GSDH
REGS1_k127_7438461_5	574966.KB898646_gene3184	1.82e-71	249.0	COG3803@1|root,COG3803@2|Bacteria,1RHYI@1224|Proteobacteria,1S40A@1236|Gammaproteobacteria,1XJPR@135619|Oceanospirillales	135619|Oceanospirillales	S	Bacterial protein of unknown function (DUF924)	-	-	-	-	-	-	-	-	-	-	-	-	DUF924
REGS1_k127_7438461_0	640081.Dsui_2789	4.165e-246	766.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2VH5S@28216|Betaproteobacteria,2KVN3@206389|Rhodocyclales	206389|Rhodocyclales	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
REGS1_k127_7438461_1	580332.Slit_0703	2.716e-223	694.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2VH18@28216|Betaproteobacteria,44VG4@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	alcE	-	1.14.15.7	ko:K00499	ko00260,map00260	-	R07409	RC00087	ko00000,ko00001,ko01000	-	-	-	Rieske,Ring_hydroxyl_A
REGS1_k127_7438461_3	580332.Slit_0702	9.814e-110	363.0	COG0697@1|root,COG0697@2|Bacteria,1MZXM@1224|Proteobacteria,2VK90@28216|Betaproteobacteria,44V07@713636|Nitrosomonadales	28216|Betaproteobacteria	EG	EamA-like transporter family	-	-	-	ko:K15270	-	-	-	-	ko00000,ko02000	2.A.7.3.7	-	-	EamA
REGS1_k127_7438461_6	1485544.JQKP01000004_gene540	1.299e-51	186.0	2CU7M@1|root,32SUS@2|Bacteria,1N1WF@1224|Proteobacteria,2VUS0@28216|Betaproteobacteria,44VVW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SpoIIAA-like	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIAA-like
REGS1_k127_7438461_4	580332.Slit_0075	1.559e-100	334.0	COG3713@1|root,COG3713@2|Bacteria,1NA1X@1224|Proteobacteria,2VVPV@28216|Betaproteobacteria	28216|Betaproteobacteria	M	MltA-interacting MipA family protein	mipA	-	-	ko:K07274	-	-	-	-	ko00000,ko02000	9.B.99.1	-	-	MipA
REGS1_k127_748866_11	220341.16502245	3.488e-05	53.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3ZJCM@590|Salmonella	1236|Gammaproteobacteria	M	OmpA-like transmembrane domain	ompA	GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022	OMP_b-brl,OmpA,OmpA_membrane
REGS1_k127_748866_2	580332.Slit_0183	3.586e-151	494.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,2VH20@28216|Betaproteobacteria,44VJM@713636|Nitrosomonadales	28216|Betaproteobacteria	M	PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
REGS1_k127_748866_1	580332.Slit_0184	6.435e-235	732.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,2VKJI@28216|Betaproteobacteria,44VNF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
REGS1_k127_748866_8	580332.Slit_0186	2.067e-42	156.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,2VSKJ@28216|Betaproteobacteria,44VZY@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
REGS1_k127_748866_0	580332.Slit_0187	6.316e-308	949.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,2VIW1@28216|Betaproteobacteria,44VNT@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
REGS1_k127_748866_5	580332.Slit_0074	1.217e-93	319.0	COG0726@1|root,COG0726@2|Bacteria,1RG9W@1224|Proteobacteria,2VRGD@28216|Betaproteobacteria	28216|Betaproteobacteria	G	PFAM Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
REGS1_k127_748866_10	292415.Tbd_2804	3.438e-05	51.0	2AFZM@1|root,3163K@2|Bacteria,1PWSR@1224|Proteobacteria,2VYPF@28216|Betaproteobacteria	28216|Betaproteobacteria	S	ATP synthase I chain	-	-	-	ko:K02116	-	-	-	-	ko00000,ko00194	3.A.2.1	-	-	ATP-synt_I
REGS1_k127_748866_4	580332.Slit_2987	2.02e-129	419.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,2VHR5@28216|Betaproteobacteria,44VW2@713636|Nitrosomonadales	28216|Betaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
REGS1_k127_748866_9	1163617.SCD_n03025	9.139e-37	139.0	COG0636@1|root,32S3K@2|Bacteria,1N1NA@1224|Proteobacteria,2VTY0@28216|Betaproteobacteria	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
REGS1_k127_748866_6	580332.Slit_2985	2.697e-65	226.0	COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,2VRMS@28216|Betaproteobacteria,44VTQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
REGS1_k127_748866_7	580332.Slit_2984	6.131e-59	209.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,2VSJV@28216|Betaproteobacteria,44VX0@713636|Nitrosomonadales	28216|Betaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
REGS1_k127_748866_3	580332.Slit_2983	8.515e-141	448.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,2VHQU@28216|Betaproteobacteria,44V6D@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
REGS1_k127_7499344_5	1485544.JQKP01000013_gene1841	4.037e-06	52.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,2VR2S@28216|Betaproteobacteria,44VSX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
REGS1_k127_7499344_0	580332.Slit_2737	2.562e-147	471.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,2VHPY@28216|Betaproteobacteria,44V1B@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
REGS1_k127_7499344_3	580332.Slit_2738	1.897e-61	217.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,2VQ0H@28216|Betaproteobacteria,44VVG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
REGS1_k127_7499344_4	580332.Slit_2739	3.739e-37	145.0	COG0228@1|root,COG0228@2|Bacteria,1MZCT@1224|Proteobacteria,2VTYP@28216|Betaproteobacteria,44W0A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
REGS1_k127_7499344_1	580332.Slit_0372	3.164e-116	384.0	COG0251@1|root,COG0251@2|Bacteria,1NQGP@1224|Proteobacteria,2VMPK@28216|Betaproteobacteria,44WCX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	pteridine-dependent deoxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
REGS1_k127_7499344_2	395494.Galf_2704	1.603e-84	284.0	COG4137@1|root,COG4137@2|Bacteria,1R3YD@1224|Proteobacteria,2VK0H@28216|Betaproteobacteria,44V5D@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Cytochrome C assembly protein	ypjD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
REGS1_k127_7580512_5	614083.AWQR01000035_gene3622	3.083e-10	68.0	COG5581@1|root,COG5581@2|Bacteria	2|Bacteria	M	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,YcgR_2
REGS1_k127_7580512_2	1236959.BAMT01000010_gene3226	1.511e-125	415.0	COG0598@1|root,COG0598@2|Bacteria,1MX09@1224|Proteobacteria,2VHCH@28216|Betaproteobacteria,2KKEF@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
REGS1_k127_7580512_4	580332.Slit_2104	2.444e-59	213.0	COG2137@1|root,COG2137@2|Bacteria,1N6P6@1224|Proteobacteria,2VTYZ@28216|Betaproteobacteria,44VWH@713636|Nitrosomonadales	28216|Betaproteobacteria	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
REGS1_k127_7580512_0	1485544.JQKP01000014_gene1886	9.512e-195	617.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,44V3M@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
REGS1_k127_7580512_3	1485544.JQKP01000005_gene366	2.232e-62	218.0	COG1546@1|root,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,2VSQF@28216|Betaproteobacteria,44VUA@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Competence-damaged protein	cinA	-	3.5.1.42	ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA
REGS1_k127_7580512_1	1485544.JQKP01000005_gene365	3.875e-163	515.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,2WGGJ@28216|Betaproteobacteria,44VB6@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide	metZ	-	2.5.1.48	ko:K01739,ko:K10764	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
REGS1_k127_7612495_25	443143.GM18_3979	1.074e-26	114.0	COG2230@1|root,COG2230@2|Bacteria,1R9QV@1224|Proteobacteria,42Z7M@68525|delta/epsilon subdivisions,2WU14@28221|Deltaproteobacteria,43TN2@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Mycolic acid cyclopropane synthetase	-	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
REGS1_k127_7612495_17	580332.Slit_1989	3.286e-60	211.0	COG2153@1|root,COG2153@2|Bacteria,1MZ86@1224|Proteobacteria,2VMR6@28216|Betaproteobacteria,44VYG@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Acetyltransferase (GNAT) domain	yjcF	-	-	-	-	-	-	-	-	-	-	-	4HBT,Acetyltransf_10
REGS1_k127_7612495_12	580332.Slit_1990	6.801e-77	261.0	COG1376@1|root,COG1376@2|Bacteria,1RHBG@1224|Proteobacteria,2VQT7@28216|Betaproteobacteria,44VUE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
REGS1_k127_7612495_13	580332.Slit_1991	6.657e-74	252.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,2VR60@28216|Betaproteobacteria,44VT1@713636|Nitrosomonadales	28216|Betaproteobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33,3.8.1.5	ko:K01563,ko:K11991	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670,R10223	RC00477,RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000,ko03016	-	-	-	Abhydrolase_1,MafB19-deam,TfoX_C
REGS1_k127_7612495_4	1458427.BAWN01000012_gene704	4.334e-233	732.0	COG3581@1|root,COG3581@2|Bacteria,1R7UD@1224|Proteobacteria	1224|Proteobacteria	I	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7612495_2	1458427.BAWN01000012_gene705	0.0	1109.0	COG1924@1|root,COG1924@2|Bacteria,1PKG6@1224|Proteobacteria,2WE9S@28216|Betaproteobacteria	28216|Betaproteobacteria	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
REGS1_k127_7612495_5	1458427.BAWN01000012_gene706	1.768e-179	569.0	COG3580@1|root,COG3580@2|Bacteria	2|Bacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
REGS1_k127_7612495_29	375286.mma_3067	6.877e-05	53.0	2EB5J@1|root,33569@2|Bacteria,1NBIN@1224|Proteobacteria,2VXI8@28216|Betaproteobacteria,4780V@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
REGS1_k127_7612495_3	153948.NAL212_2775	2.477e-254	802.0	COG2857@1|root,COG2857@2|Bacteria,1QWB9@1224|Proteobacteria,2WGY5@28216|Betaproteobacteria,371Z2@32003|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome c1	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7612495_28	765913.ThidrDRAFT_0023	6.677e-11	70.0	2EVMX@1|root,33P1X@2|Bacteria,1NK24@1224|Proteobacteria,1SIT5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CheW
REGS1_k127_7612495_1	365046.Rta_19330	0.0	1117.0	COG0643@1|root,COG0784@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,2VJSZ@28216|Betaproteobacteria,4AGK7@80864|Comamonadaceae	28216|Betaproteobacteria	T	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW,HATPase_c,Hpt,Response_reg
REGS1_k127_7612495_6	365046.Rta_19320	9.283e-145	481.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2W05Y@28216|Betaproteobacteria,4AGS3@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K02660	ko02020,ko02025,map02020,map02025	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	HAMP,MCPsignal,dCache_1
REGS1_k127_7612495_22	365046.Rta_19310	6.432e-35	141.0	COG0835@1|root,COG0835@2|Bacteria,1Q0RG@1224|Proteobacteria,2W5MM@28216|Betaproteobacteria,4AIWF@80864|Comamonadaceae	28216|Betaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
REGS1_k127_7612495_21	365046.Rta_19290	6.803e-47	172.0	COG0745@1|root,COG0745@2|Bacteria	365046.Rta_19290|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7612495_15	365046.Rta_19280	5.483e-68	241.0	COG0745@1|root,COG0745@2|Bacteria,1N2T7@1224|Proteobacteria,2VSUA@28216|Betaproteobacteria,4AIKH@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_7612495_7	580332.Slit_2685	4.519e-111	364.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,44V3G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
REGS1_k127_7612495_10	649639.Bcell_3136	4.41e-84	287.0	COG1809@1|root,COG1809@2|Bacteria,1V20V@1239|Firmicutes,4HDSM@91061|Bacilli,1ZEWC@1386|Bacillus	91061|Bacilli	S	synthase	yitD	-	4.4.1.19	ko:K08097	ko00680,ko01120,map00680,map01120	M00358	R07476	RC01799	ko00000,ko00001,ko00002,ko01000	-	-	-	ComA
REGS1_k127_7612495_19	1356854.N007_19125	7.256e-55	195.0	COG3565@1|root,COG3565@2|Bacteria,1V6AX@1239|Firmicutes,4HIET@91061|Bacilli	91061|Bacilli	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06991	-	-	-	-	ko00000	-	-	-	Glyoxalase
REGS1_k127_7612495_18	1382358.JHVN01000011_gene2017	3.367e-60	216.0	COG2045@1|root,COG2045@2|Bacteria,1TTEV@1239|Firmicutes,4HGDY@91061|Bacilli	91061|Bacilli	H	Belongs to the ComB family	-	GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
REGS1_k127_7612495_16	365046.Rta_19280	1.424e-64	231.0	COG0745@1|root,COG0745@2|Bacteria,1N2T7@1224|Proteobacteria,2VSUA@28216|Betaproteobacteria,4AIKH@80864|Comamonadaceae	28216|Betaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
REGS1_k127_7612495_23	1485544.JQKP01000004_gene442	4.146e-34	139.0	COG4654@1|root,COG4654@2|Bacteria	2|Bacteria	C	Cytochrome c, class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_7612495_11	1163617.SCD_n01991	5.614e-82	282.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,2VQ65@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7612495_0	580332.Slit_2025	0.0	2128.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,2VHTE@28216|Betaproteobacteria,44VBS@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
REGS1_k127_7612495_9	580332.Slit_2026	4.384e-106	354.0	COG0063@1|root,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,2VJZD@28216|Betaproteobacteria,44VJ1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136	ko:K17758	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
REGS1_k127_7612495_20	580332.Slit_2027	1.071e-54	197.0	2BWTE@1|root,32YDB@2|Bacteria,1N0HE@1224|Proteobacteria,2VYW4@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2937)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2937
REGS1_k127_7612495_8	261292.Nit79A3_1349	7.339e-109	357.0	COG0421@1|root,COG0421@2|Bacteria,1RBWW@1224|Proteobacteria,2VK7S@28216|Betaproteobacteria,372CE@32003|Nitrosomonadales	28216|Betaproteobacteria	H	Spermine/spermidine synthase domain	speE1	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
REGS1_k127_7612495_27	580332.Slit_2029	1.895e-17	88.0	2ENVQ@1|root,33GGS@2|Bacteria,1NGVT@1224|Proteobacteria,2VY6X@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2934)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2934
REGS1_k127_7612495_14	1288494.EBAPG3_14050	1.537e-69	244.0	COG3427@1|root,COG3427@2|Bacteria,1N55Y@1224|Proteobacteria,2VTZD@28216|Betaproteobacteria,3748Z@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
REGS1_k127_7645584_5	395494.Galf_2878	6.612e-14	76.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,2VI8I@28216|Betaproteobacteria,44VF5@713636|Nitrosomonadales	28216|Betaproteobacteria	CO	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_2,Thioredoxin_7
REGS1_k127_7645584_4	1485544.JQKP01000002_gene1456	1.77e-38	151.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,2VUC8@28216|Betaproteobacteria,44VZ7@713636|Nitrosomonadales	28216|Betaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
REGS1_k127_7645584_1	580332.Slit_2849	4.905e-160	509.0	COG1466@1|root,COG1466@2|Bacteria,1MWYT@1224|Proteobacteria,2VIKX@28216|Betaproteobacteria,44VB7@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA polymerase III, delta subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delt_C,DNA_pol3_delta
REGS1_k127_7645584_3	580332.Slit_2848	2.087e-42	161.0	COG2980@1|root,COG2980@2|Bacteria,1N13K@1224|Proteobacteria,2VU54@28216|Betaproteobacteria,44VZ0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane	lptE	-	-	ko:K03643	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptE
REGS1_k127_7645584_0	580332.Slit_2847	0.0	1517.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,2VH2J@28216|Betaproteobacteria,44V3Z@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
REGS1_k127_7645584_2	580332.Slit_2685	3.693e-46	168.0	COG0730@1|root,COG0730@2|Bacteria,1R3V4@1224|Proteobacteria,2VKXN@28216|Betaproteobacteria,44V3G@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Sulfite exporter TauE/SafE	-	-	-	-	-	-	-	-	-	-	-	-	TauE
REGS1_k127_7655139_0	580332.Slit_0968	0.0	1055.0	COG2838@1|root,COG2838@2|Bacteria,1MV6Q@1224|Proteobacteria,2VI36@28216|Betaproteobacteria,44VC6@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM Isocitrate dehydrogenase NADP-dependent monomeric type	icd_2	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	IDH
REGS1_k127_7655139_4	580332.Slit_1294	1.228e-86	289.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,2VRM9@28216|Betaproteobacteria,44VRI@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Phosphoribosyl transferase domain	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
REGS1_k127_7655139_2	580332.Slit_1293	1.466e-134	434.0	COG1210@1|root,COG1210@2|Bacteria,1MV5F@1224|Proteobacteria,2VH00@28216|Betaproteobacteria,44VIF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
REGS1_k127_7655139_1	580332.Slit_1292	1.049e-309	963.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,2VIDE@28216|Betaproteobacteria,44VJW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
REGS1_k127_7655139_3	1485544.JQKP01000013_gene1797	3.902e-97	328.0	COG3115@1|root,COG3115@2|Bacteria,1NJ6D@1224|Proteobacteria,2VHQ7@28216|Betaproteobacteria,44VC1@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins	zipA	-	-	-	-	-	-	-	-	-	-	-	ZipA_C
REGS1_k127_7655139_6	1122201.AUAZ01000003_gene1905	1.29e-14	82.0	COG0715@1|root,COG0715@2|Bacteria,1MVJA@1224|Proteobacteria,1S43R@1236|Gammaproteobacteria,468AX@72275|Alteromonadaceae	1236|Gammaproteobacteria	P	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
REGS1_k127_7655139_5	395494.Galf_1197	6e-68	233.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,44V3T@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
REGS1_k127_7672248_8	246969.TAM4_499	5.194e-05	57.0	COG0515@1|root,arCOG00372@1|root,arCOG03264@1|root,arCOG00372@2157|Archaea,arCOG03264@2157|Archaea,arCOG03682@2157|Archaea,2XWYZ@28890|Euryarchaeota,2437Z@183968|Thermococci	183968|Thermococci	T	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
REGS1_k127_7672248_9	485917.Phep_3796	0.0006183	48.0	COG1629@1|root,COG1629@2|Bacteria,4NQGN@976|Bacteroidetes,1IX64@117747|Sphingobacteriia	976|Bacteroidetes	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2
REGS1_k127_7672248_3	580332.Slit_0879	4.965e-186	614.0	COG2202@1|root,COG3829@1|root,COG5001@1|root,COG2202@2|Bacteria,COG3829@2|Bacteria,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2VH3V@28216|Betaproteobacteria,44W76@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,MASE1,PAS_3,PAS_9
REGS1_k127_7672248_6	1485544.JQKP01000004_gene496	9.726e-108	355.0	COG0428@1|root,COG0428@2|Bacteria,1R40E@1224|Proteobacteria,2VN69@28216|Betaproteobacteria,44UZT@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ZIP Zinc transporter	-	-	-	ko:K16267	-	-	-	-	ko00000,ko02000	2.A.5.4.11	-	-	Zip
REGS1_k127_7672248_0	580332.Slit_1579	0.0	1382.0	COG1129@1|root,COG4177@1|root,COG1129@2|Bacteria,COG4177@2|Bacteria,1QU8R@1224|Proteobacteria,2WHYG@28216|Betaproteobacteria	28216|Betaproteobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
REGS1_k127_7672248_4	580332.Slit_1580	1.286e-156	499.0	COG0559@1|root,COG0559@2|Bacteria,1N0XX@1224|Proteobacteria,2VME0@28216|Betaproteobacteria	28216|Betaproteobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
REGS1_k127_7672248_1	580332.Slit_1581	5.328e-205	644.0	COG0683@1|root,COG0683@2|Bacteria,1MX94@1224|Proteobacteria,2VHQ4@28216|Betaproteobacteria	28216|Betaproteobacteria	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
REGS1_k127_7672248_2	580332.Slit_2098	1.436e-190	596.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,2VHR7@28216|Betaproteobacteria,44VFU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
REGS1_k127_7672248_7	1485544.JQKP01000003_gene96	1.984e-26	111.0	COG4391@1|root,COG4391@2|Bacteria,1N7QM@1224|Proteobacteria,2WAN7@28216|Betaproteobacteria,44W2Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Zinc-finger domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHCC
REGS1_k127_7672248_5	580332.Slit_2100	9.712e-120	391.0	COG0859@1|root,COG0859@2|Bacteria,1MXA2@1224|Proteobacteria,2VHHX@28216|Betaproteobacteria,44UZE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Glycosyltransferase family 9 (heptosyltransferase)	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
REGS1_k127_7672798_15	1005048.CFU_0951	1.468e-11	72.0	2E193@1|root,32WPE@2|Bacteria,1PA4R@1224|Proteobacteria,2VVMZ@28216|Betaproteobacteria,474M6@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7672798_10	795666.MW7_0648	4.278e-42	157.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,2VUKU@28216|Betaproteobacteria,1KAN3@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
REGS1_k127_7672798_7	234267.Acid_6266	9.965e-64	222.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
REGS1_k127_7672798_0	1005048.CFU_2115	1.595e-285	887.0	COG1502@1|root,COG1502@2|Bacteria,1R9CI@1224|Proteobacteria,2WFC7@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
REGS1_k127_7672798_5	414996.IL38_12050	1.897e-69	241.0	COG0262@1|root,COG0262@2|Bacteria,2HG35@201174|Actinobacteria,40AE3@622450|Actinopolysporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_7672798_6	706587.Desti_3215	5.602e-66	229.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,42QW0@68525|delta/epsilon subdivisions,2WMZW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
REGS1_k127_7672798_4	1429916.X566_22220	1.162e-78	265.0	COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,2UDER@28211|Alphaproteobacteria,3K4ND@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Cupin domain	manC	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
REGS1_k127_7672798_9	395494.Galf_2897	9.059e-53	192.0	COG3536@1|root,COG3536@2|Bacteria,1MZ5M@1224|Proteobacteria,2VR9K@28216|Betaproteobacteria,44VXY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
REGS1_k127_7672798_1	395494.Galf_2898	2.449e-143	458.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,2VHBM@28216|Betaproteobacteria,44VA7@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
REGS1_k127_7672798_2	1144664.F973_01194	2.239e-89	295.0	2B07T@1|root,31SIM@2|Bacteria,1QQ3R@1224|Proteobacteria,1TNX2@1236|Gammaproteobacteria,3NRH7@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7672798_8	580332.Slit_2972	2.096e-55	199.0	COG2824@1|root,COG2824@2|Bacteria,1RGUU@1224|Proteobacteria,2VSKS@28216|Betaproteobacteria,44VY9@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM alkylphosphonate utilization operon protein PhnA	phnA	-	-	ko:K06193	ko01120,map01120	-	-	-	ko00000	-	-	-	PhnA,PhnA_Zn_Ribbon
REGS1_k127_7672798_3	580332.Slit_2974	9.386e-86	288.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,2VQ14@28216|Betaproteobacteria,44VQS@713636|Nitrosomonadales	28216|Betaproteobacteria	J	RNA pseudouridylate synthase	rluA	-	5.4.99.28,5.4.99.29	ko:K06177	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
REGS1_k127_7672798_13	580332.Slit_2997	3.081e-17	82.0	COG0230@1|root,COG0230@2|Bacteria,1NGGS@1224|Proteobacteria,2VXTS@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
REGS1_k127_7672798_14	1485544.JQKP01000007_gene1996	8.165e-17	85.0	COG0594@1|root,COG0594@2|Bacteria,1PXBW@1224|Proteobacteria,2WCTM@28216|Betaproteobacteria,44WN7@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Ribonuclease P	-	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
REGS1_k127_7672798_11	395494.Galf_2947	4.799e-30	124.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,2VVTR@28216|Betaproteobacteria,44W1S@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
REGS1_k127_7672798_12	323848.Nmul_A2776	1.269e-28	121.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,2VHIA@28216|Betaproteobacteria,371S5@32003|Nitrosomonadales	28216|Betaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
REGS1_k127_7701659_6	381666.H16_B2395	0.0008199	48.0	29A0E@1|root,2ZX1Z@2|Bacteria,1P6RU@1224|Proteobacteria,2W64A@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7701659_0	580332.Slit_2168	2.788e-223	706.0	COG4585@1|root,COG4585@2|Bacteria,1QXNA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11617	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3,PAS_4
REGS1_k127_7701659_3	162425.CADANIAP00004113	1.013e-31	136.0	COG0666@1|root,KOG4177@2759|Eukaryota,38BVK@33154|Opisthokonta,3NW9Q@4751|Fungi,3QJDH@4890|Ascomycota	4751|Fungi	M	ankyrin repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4,NACHT
REGS1_k127_7701659_1	1009370.ALO_01579	9.49e-40	161.0	COG0666@1|root,COG0666@2|Bacteria,1V7AY@1239|Firmicutes,4H628@909932|Negativicutes	909932|Negativicutes	S	Ankyrin repeats (3 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,Ank_4
REGS1_k127_7701659_4	4792.ETI35064	2.963e-26	117.0	COG0666@1|root,KOG0504@2759|Eukaryota,KOG4177@2759|Eukaryota,3Q7Q6@4776|Peronosporales	4776|Peronosporales	S	Ankyrin repeats (many copies)	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2
REGS1_k127_7701659_2	1000565.METUNv1_03477	1.042e-37	149.0	2DM6D@1|root,31WQ8@2|Bacteria,1MZ7P@1224|Proteobacteria,2VUHB@28216|Betaproteobacteria,2KYYM@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7701659_5	1268622.AVS7_04286	1.404e-23	108.0	COG2706@1|root,COG2706@2|Bacteria,1RB38@1224|Proteobacteria,2VSAM@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
REGS1_k127_7704159_11	1121035.AUCH01000006_gene668	1.862e-11	74.0	2AIHJ@1|root,318ZE@2|Bacteria,1Q18Q@1224|Proteobacteria,2W6AT@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_14	1121022.ABENE_00200	0.0005841	51.0	2DR2Z@1|root,339YC@2|Bacteria,1NQ6J@1224|Proteobacteria,2UNJD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3828
REGS1_k127_7704159_10	1235457.C404_09880	1.516e-11	78.0	COG3179@1|root,COG3179@2|Bacteria,1QV3K@1224|Proteobacteria,2W443@28216|Betaproteobacteria,1KA1T@119060|Burkholderiaceae	28216|Betaproteobacteria	S	chitinase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_9	1003200.AXXA_27965	7.341e-16	85.0	2DPYK@1|root,333Z3@2|Bacteria,1NEX0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_0	360910.BAV0429	2.361e-181	609.0	28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,2VSX1@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_5	1003200.AXXA_27975	3.389e-62	220.0	2DZ82@1|root,32V6V@2|Bacteria,1N3UK@1224|Proteobacteria,2VY68@28216|Betaproteobacteria,3T7VI@506|Alcaligenaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_12	1115515.EV102420_06_00380	1.868e-05	49.0	2EFYE@1|root,339QJ@2|Bacteria,1NISM@1224|Proteobacteria,1SIFN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_13	1344012.ATMI01000056_gene1741	0.0005125	48.0	COG5492@1|root,COG5492@2|Bacteria,1Q5FE@1224|Proteobacteria,1TKWB@1236|Gammaproteobacteria,4BVXP@82986|Tatumella	1236|Gammaproteobacteria	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
REGS1_k127_7704159_1	517433.PanABDRAFT_3535	1.635e-117	386.0	28HXV@1|root,2Z83C@2|Bacteria,1PJBP@1224|Proteobacteria,1RYDU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_6	557598.LHK_01541	5.825e-40	157.0	2AXQF@1|root,31PR8@2|Bacteria,1RKX8@1224|Proteobacteria,2W377@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_7	360910.BAV0423	2.597e-26	111.0	2BWQK@1|root,336Z4@2|Bacteria,1NFES@1224|Proteobacteria,2W4EC@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7704159_3	697282.Mettu_0017	1.912e-63	225.0	COG0515@1|root,COG0515@2|Bacteria,1N577@1224|Proteobacteria,1S5IV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Coa1
REGS1_k127_7704159_2	62928.azo2987	1.321e-74	254.0	COG0262@1|root,COG0262@2|Bacteria,1RH02@1224|Proteobacteria,2VQ3W@28216|Betaproteobacteria	28216|Betaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
REGS1_k127_7704159_8	497964.CfE428DRAFT_3034	1.781e-22	101.0	2E5G6@1|root,3307V@2|Bacteria,46VT4@74201|Verrucomicrobia	74201|Verrucomicrobia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
REGS1_k127_7704159_4	1121468.AUBR01000036_gene1308	4.129e-63	227.0	COG2203@1|root,COG3437@1|root,COG3605@1|root,COG4936@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG3605@2|Bacteria,COG4936@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42JGC@68295|Thermoanaerobacterales	186801|Clostridia	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,PocR,SBP_bac_3
REGS1_k127_7730213_2	1158292.JPOE01000002_gene1671	4.104e-197	636.0	COG4548@1|root,COG4548@2|Bacteria,1MVBZ@1224|Proteobacteria,2VJJW@28216|Betaproteobacteria,1KKYF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	P	von Willebrand factor (vWF) type A domain	cbbO	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
REGS1_k127_7730213_7	1485544.JQKP01000005_gene287	2.394e-106	354.0	COG0810@1|root,COG0810@2|Bacteria,1MUMT@1224|Proteobacteria,2VKSW@28216|Betaproteobacteria,44VI1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TonB C terminal	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
REGS1_k127_7730213_0	580332.Slit_0508	7.861e-302	937.0	COG0557@1|root,COG0557@2|Bacteria,1NGSQ@1224|Proteobacteria,2VHMM@28216|Betaproteobacteria,44VP2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	RNB	rnb	-	3.1.13.1	ko:K01147	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNB
REGS1_k127_7730213_12	267608.RSc3104	8.206e-21	101.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2VW0M@28216|Betaproteobacteria,1K77D@119060|Burkholderiaceae	28216|Betaproteobacteria	DTZ	EF-hand domain pair	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
REGS1_k127_7730213_10	395494.Galf_2084	1.221e-28	119.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44W1Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_7730213_8	1485544.JQKP01000002_gene1412	4.276e-91	305.0	2C8XG@1|root,2Z7PK@2|Bacteria,1RA5I@1224|Proteobacteria,2VQGY@28216|Betaproteobacteria,44VSN@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF4197)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4197
REGS1_k127_7730213_9	1265502.KB905969_gene1230	1.463e-51	190.0	2C73B@1|root,330Z7@2|Bacteria,1N4FW@1224|Proteobacteria,2W6GV@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7730213_4	701347.Entcl_2153	1.036e-147	489.0	COG1311@1|root,COG1311@2|Bacteria,1NRG6@1224|Proteobacteria	1224|Proteobacteria	L	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
REGS1_k127_7730213_5	1120999.JONM01000017_gene75	4.989e-127	415.0	COG0430@1|root,COG0430@2|Bacteria,1MX7Q@1224|Proteobacteria,2VHYS@28216|Betaproteobacteria	28216|Betaproteobacteria	A	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP	rtcA	-	6.5.1.4	ko:K01974	-	-	-	-	ko00000,ko01000	-	-	-	RTC,RTC_insert
REGS1_k127_7730213_6	1123487.KB892834_gene2649	3.64e-121	398.0	COG3541@1|root,COG3541@2|Bacteria,1MYFT@1224|Proteobacteria,2VJ6B@28216|Betaproteobacteria,2KY5S@206389|Rhodocyclales	206389|Rhodocyclales	S	Predicted nucleotidyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Nuc-transf
REGS1_k127_7730213_1	1121035.AUCH01000018_gene2785	5.723e-233	725.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,2VJ89@28216|Betaproteobacteria,2KV94@206389|Rhodocyclales	206389|Rhodocyclales	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
REGS1_k127_7730213_11	1116472.MGMO_142c00070	1.943e-26	115.0	2CD2E@1|root,330VS@2|Bacteria,1N86R@1224|Proteobacteria,1SE64@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Probable zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zf-trcl
REGS1_k127_7730213_3	748247.AZKH_2569	4.781e-183	578.0	COG0330@1|root,COG0330@2|Bacteria,1MWMD@1224|Proteobacteria,2VKGC@28216|Betaproteobacteria,2KY8X@206389|Rhodocyclales	206389|Rhodocyclales	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
REGS1_k127_7789971_11	395494.Galf_0356	8.9e-07	51.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2VTZQ@28216|Betaproteobacteria,44WIP@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Polymer-forming cytoskeletal	ccmA	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
REGS1_k127_7789971_8	580332.Slit_2454	5.575e-67	236.0	28IJP@1|root,2Z8KI@2|Bacteria,1R9DP@1224|Proteobacteria,2VHRX@28216|Betaproteobacteria,44WF0@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7789971_2	580332.Slit_2455	1.297e-181	580.0	COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,2VJD7@28216|Betaproteobacteria,44V0R@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
REGS1_k127_7789971_7	580332.Slit_2456	4.59e-67	230.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,2VR5R@28216|Betaproteobacteria,44VSY@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
REGS1_k127_7789971_6	1485544.JQKP01000004_gene459	1.877e-80	269.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,2VQ07@28216|Betaproteobacteria,44VQJ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
REGS1_k127_7789971_5	1095769.CAHF01000005_gene1503	1.47e-87	291.0	COG1573@1|root,COG1573@2|Bacteria,1R9XV@1224|Proteobacteria,2W0X4@28216|Betaproteobacteria,477E5@75682|Oxalobacteraceae	28216|Betaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	UDG
REGS1_k127_7789971_0	580332.Slit_0165	1.409e-217	680.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,2VIN5@28216|Betaproteobacteria,44V0A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Probable RNA and SrmB- binding site of polymerase A	cca	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
REGS1_k127_7789971_1	580332.Slit_0164	5.273e-214	685.0	COG0741@1|root,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,2VHPK@28216|Betaproteobacteria,44VGW@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Soluble lytic murein transglycosylase L domain	slt	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L
REGS1_k127_7789971_3	357808.RoseRS_0661	2.828e-179	580.0	COG1132@1|root,COG1132@2|Bacteria,2G7QD@200795|Chloroflexi,376IN@32061|Chloroflexia	32061|Chloroflexia	P	PFAM ABC transporter related	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
REGS1_k127_7789971_10	43989.cce_2329	3.506e-22	101.0	2CBZI@1|root,339ZR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7789971_4	747365.Thena_1112	3.676e-96	324.0	COG0189@1|root,COG0189@2|Bacteria,1VK93@1239|Firmicutes,24NYP@186801|Clostridia	186801|Clostridia	HJ	ligase activity	-	-	-	-	-	-	-	-	-	-	-	-	RimK
REGS1_k127_7789971_9	395494.Galf_2345	6.769e-51	181.0	COG0307@1|root,COG0307@2|Bacteria,1MUMB@1224|Proteobacteria,2VIU0@28216|Betaproteobacteria,44V83@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Lumazine binding domain	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
REGS1_k127_7811200_3	580332.Slit_2088	2.477e-160	509.0	COG0761@1|root,COG0761@2|Bacteria,1MU7G@1224|Proteobacteria,2VHM8@28216|Betaproteobacteria,44V90@713636|Nitrosomonadales	28216|Betaproteobacteria	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
REGS1_k127_7811200_8	1485544.JQKP01000002_gene1383	2.623e-57	205.0	COG0597@1|root,COG0597@2|Bacteria,1RGV9@1224|Proteobacteria,2VSEP@28216|Betaproteobacteria,44VXG@713636|Nitrosomonadales	28216|Betaproteobacteria	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
REGS1_k127_7811200_0	580332.Slit_2090	0.0	1572.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,2VIEJ@28216|Betaproteobacteria,44V7X@713636|Nitrosomonadales	28216|Betaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
REGS1_k127_7811200_5	395494.Galf_2053	1.779e-126	413.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,2VHIP@28216|Betaproteobacteria,44VNX@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
REGS1_k127_7811200_7	580332.Slit_1052	1.23e-60	213.0	COG0515@1|root,COG0515@2|Bacteria,1NN82@1224|Proteobacteria,2VXXH@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7811200_4	1485544.JQKP01000007_gene1981	3.597e-141	451.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,2VJC3@28216|Betaproteobacteria,44VID@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
REGS1_k127_7811200_9	395494.Galf_2153	4.059e-30	122.0	COG2913@1|root,COG2913@2|Bacteria,1N6YW@1224|Proteobacteria,2VRC6@28216|Betaproteobacteria,44W20@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamE	-	-	ko:K06186	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	SmpA_OmlA
REGS1_k127_7811200_1	580332.Slit_0525	3.985e-204	643.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1PPH1@1224|Proteobacteria,2W9GU@28216|Betaproteobacteria,44WKA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
REGS1_k127_7811200_6	580332.Slit_1446	1.347e-125	408.0	COG0492@1|root,COG0492@2|Bacteria,1R12A@1224|Proteobacteria,2WHYF@28216|Betaproteobacteria	28216|Betaproteobacteria	O	ferredoxin-NADP+ reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7811200_2	580332.Slit_1447	2.084e-160	510.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,2WHYC@28216|Betaproteobacteria,44WNC@713636|Nitrosomonadales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
REGS1_k127_7851994_17	580332.Slit_1605	6.833e-22	95.0	COG2274@1|root,COG2274@2|Bacteria,1R2T0@1224|Proteobacteria,2VP2B@28216|Betaproteobacteria,44W71@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K11004	ko02010,ko03070,ko05133,map02010,map03070,map05133	M00325,M00575	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1.109.1,3.A.1.109.2	-	-	ABC_membrane,ABC_tran
REGS1_k127_7851994_7	1485544.JQKP01000014_gene1877	1.188e-132	434.0	COG1947@1|root,COG1947@2|Bacteria,1MVU3@1224|Proteobacteria,2VHK3@28216|Betaproteobacteria,44V4C@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
REGS1_k127_7851994_3	580332.Slit_2354	5.285e-179	565.0	COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,2VHU0@28216|Betaproteobacteria,44VJC@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
REGS1_k127_7851994_11	580332.Slit_2353	4.173e-96	322.0	COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,2VQNU@28216|Betaproteobacteria,44VSG@713636|Nitrosomonadales	28216|Betaproteobacteria	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
REGS1_k127_7851994_10	580332.Slit_2352	4.9e-100	328.0	COG0193@1|root,COG0193@2|Bacteria,1MX1P@1224|Proteobacteria,2VKKJ@28216|Betaproteobacteria,44VSB@713636|Nitrosomonadales	28216|Betaproteobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
REGS1_k127_7851994_1	580332.Slit_2351	7.877e-220	685.0	COG0012@1|root,COG0012@2|Bacteria,1MVM4@1224|Proteobacteria,2VJ1W@28216|Betaproteobacteria,44VKN@713636|Nitrosomonadales	28216|Betaproteobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
REGS1_k127_7851994_14	338969.Rfer_2088	1.668e-52	191.0	COG0500@1|root,COG2226@2|Bacteria,1RAAC@1224|Proteobacteria,2VQJ2@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_7851994_0	1485544.JQKP01000002_gene1351	4.966e-222	695.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2VH16@28216|Betaproteobacteria,44VDC@713636|Nitrosomonadales	28216|Betaproteobacteria	JKL	DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA	rhlE	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
REGS1_k127_7851994_2	580332.Slit_2348	4.295e-186	587.0	COG2334@1|root,COG2334@2|Bacteria,1MU2Q@1224|Proteobacteria,2VI9A@28216|Betaproteobacteria,44V37@713636|Nitrosomonadales	28216|Betaproteobacteria	H	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response	srkA	-	-	-	-	-	-	-	-	-	-	-	APH
REGS1_k127_7851994_15	1288494.EBAPG3_21560	8.197e-49	177.0	COG3012@1|root,COG3012@2|Bacteria,1MZZK@1224|Proteobacteria,2VTZE@28216|Betaproteobacteria,3737U@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Belongs to the UPF0225 family	ychJ	-	-	ko:K09858	-	-	-	-	ko00000	-	-	-	SEC-C
REGS1_k127_7851994_12	1163617.SCD_n01089	2.27e-89	299.0	COG2716@1|root,COG2716@2|Bacteria,1R7W7@1224|Proteobacteria	1224|Proteobacteria	E	Glycine cleavage system	gcvR	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
REGS1_k127_7851994_13	395494.Galf_2310	7.922e-78	266.0	COG2862@1|root,COG2862@2|Bacteria,1RFUX@1224|Proteobacteria,2VRH2@28216|Betaproteobacteria,44VS8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Uncharacterized protein family, UPF0114	-	-	-	-	-	-	-	-	-	-	-	-	UPF0114
REGS1_k127_7851994_6	580332.Slit_0742	7.457e-142	462.0	COG1295@1|root,COG1295@2|Bacteria,1QICW@1224|Proteobacteria,2VJNM@28216|Betaproteobacteria,44VKC@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Virulence factor BrkB	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
REGS1_k127_7851994_5	580332.Slit_0169	1.723e-164	522.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,2VHWH@28216|Betaproteobacteria,44VEK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
REGS1_k127_7851994_9	1485544.JQKP01000002_gene1396	6.218e-111	362.0	COG1028@1|root,COG1028@2|Bacteria,1MUUV@1224|Proteobacteria,2VK0U@28216|Betaproteobacteria,44VK9@713636|Nitrosomonadales	28216|Betaproteobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.1.1.100,1.5.1.33	ko:K00059,ko:K03793	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
REGS1_k127_7851994_4	580332.Slit_0167	1.648e-169	541.0	COG1565@1|root,COG1565@2|Bacteria,1N3CJ@1224|Proteobacteria,2VHBE@28216|Betaproteobacteria,44V36@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
REGS1_k127_7851994_16	1485544.JQKP01000011_gene761	6.109e-38	151.0	2ETRW@1|root,33M9C@2|Bacteria,1NEBE@1224|Proteobacteria,2VXIY@28216|Betaproteobacteria,44W11@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7851994_8	1485544.JQKP01000011_gene762	1.353e-114	377.0	COG4692@1|root,COG4692@2|Bacteria,1Q1EG@1224|Proteobacteria,2VMXN@28216|Betaproteobacteria,44VCC@713636|Nitrosomonadales	28216|Betaproteobacteria	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
REGS1_k127_7994381_10	395494.Galf_0147	2.232e-133	432.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,2VJN0@28216|Betaproteobacteria,44V0P@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)	pdxA	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
REGS1_k127_7994381_9	580332.Slit_0044	1.577e-151	490.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,2VHHS@28216|Betaproteobacteria,44VEF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3,SurA_N
REGS1_k127_7994381_4	580332.Slit_0045	2.806e-263	830.0	COG1452@1|root,COG1452@2|Bacteria,1MUJC@1224|Proteobacteria,2VIJ7@28216|Betaproteobacteria,44V59@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	lptD	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA,OstA_C
REGS1_k127_7994381_8	580332.Slit_0046	4.811e-194	610.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,2VHBC@28216|Betaproteobacteria,44VMI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
REGS1_k127_7994381_16	1485544.JQKP01000020_gene55	2.258e-97	324.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,2VJUN@28216|Betaproteobacteria,44V8V@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Nucleotidyl transferase	rmlA	-	2.7.7.99	ko:K00992	ko00520,ko01100,map00520,map01100	-	R11025	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
REGS1_k127_7994381_7	1485544.JQKP01000020_gene54	1.186e-203	646.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,2VHQI@28216|Betaproteobacteria,44VB9@713636|Nitrosomonadales	28216|Betaproteobacteria	E	peptidase M24B X-Pro dipeptidase aminopeptidase domain protein	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
REGS1_k127_7994381_23	1485544.JQKP01000020_gene53	1.266e-42	160.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,44V7V@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
REGS1_k127_7994381_14	1485544.JQKP01000020_gene53	1.082e-118	385.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VKV7@28216|Betaproteobacteria,44V7V@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiH	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_3
REGS1_k127_7994381_15	395494.Galf_2281	5.102e-117	387.0	COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,2VIJV@28216|Betaproteobacteria,44V16@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Part of the ABC transporter complex PstSACB involved in phosphate import	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
REGS1_k127_7994381_12	1485544.JQKP01000012_gene2108	1.066e-122	398.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,2VHEW@28216|Betaproteobacteria,44V26@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
REGS1_k127_7994381_20	580332.Slit_1378	1.398e-60	212.0	COG3439@1|root,COG3439@2|Bacteria,1RH9Z@1224|Proteobacteria,2VTC8@28216|Betaproteobacteria,44WK9@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
REGS1_k127_7994381_1	686340.Metal_2036	0.0	1062.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,1RMP2@1236|Gammaproteobacteria,1XESA@135618|Methylococcales	135618|Methylococcales	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
REGS1_k127_7994381_17	580332.Slit_2695	6.354e-88	294.0	COG1192@1|root,COG1192@2|Bacteria,1QBJX@1224|Proteobacteria,2VJNI@28216|Betaproteobacteria,44VQX@713636|Nitrosomonadales	28216|Betaproteobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
REGS1_k127_7994381_22	580332.Slit_2780	9.751e-47	171.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_7994381_24	580332.Slit_2693	1.391e-32	131.0	COG4654@1|root,COG4654@2|Bacteria,1N6UN@1224|Proteobacteria,2VW1Y@28216|Betaproteobacteria,44WJY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM cytochrome c class I	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrom_C,Cytochrome_CBB3
REGS1_k127_7994381_0	1112274.KI911560_gene909	0.0	2251.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,2VHUY@28216|Betaproteobacteria,2KM55@206350|Nitrosomonadales	206350|Nitrosomonadales	E	glutamate synthase, alpha subunit domain protein	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
REGS1_k127_7994381_3	580332.Slit_0116	1.804e-283	874.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,2VIHR@28216|Betaproteobacteria,44VJA@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM glutamate synthase, NADH NADPH, small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
REGS1_k127_7994381_5	1485544.JQKP01000002_gene1407	2.194e-218	681.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,2VHC2@28216|Betaproteobacteria,44V4K@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
REGS1_k127_7994381_2	580332.Slit_0118	0.0	1045.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,2VINT@28216|Betaproteobacteria,44UY9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
REGS1_k127_7994381_18	1485544.JQKP01000002_gene1405	3.121e-79	271.0	COG0723@1|root,COG0723@2|Bacteria,1RAA2@1224|Proteobacteria,2VK46@28216|Betaproteobacteria,44WFV@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal	-	-	1.10.2.2	ko:K00411	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske,UCR_Fe-S_N
REGS1_k127_7994381_6	1485544.JQKP01000002_gene1404	3.498e-218	682.0	COG1290@1|root,COG1290@2|Bacteria,1MV97@1224|Proteobacteria,2VHP5@28216|Betaproteobacteria,44WAZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome b(N-terminal)/b6/petB	petB	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrome_B
REGS1_k127_7994381_19	1485544.JQKP01000002_gene1403	8.166e-74	257.0	COG2857@1|root,COG2857@2|Bacteria,1QFU2@1224|Proteobacteria,2VIR6@28216|Betaproteobacteria,44WH8@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Cytochrome C1 family	petC	-	-	ko:K00413	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_C1
REGS1_k127_7994381_21	1485544.JQKP01000002_gene1645	3.482e-49	179.0	COG2010@1|root,COG2010@2|Bacteria,1NDHN@1224|Proteobacteria	1224|Proteobacteria	C	Planctomycete cytochrome C	-	-	-	-	-	-	-	-	-	-	-	-	PSCyt1
REGS1_k127_7994381_13	582744.Msip34_0215	4.428e-120	389.0	293CN@1|root,2Z8R1@2|Bacteria,1R8CI@1224|Proteobacteria,2VZKD@28216|Betaproteobacteria,2KKCK@206350|Nitrosomonadales	206350|Nitrosomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_7994381_11	1485544.JQKP01000002_gene1402	3.094e-126	409.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,44VFX@713636|Nitrosomonadales	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	-	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
REGS1_k127_8029585_0	479435.Kfla_3049	7.871e-105	360.0	COG1524@1|root,COG1524@2|Bacteria,2HH0Q@201174|Actinobacteria,4DP40@85009|Propionibacteriales	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_2,Phosphodiest
REGS1_k127_8029585_1	1313172.YM304_06270	1.305e-69	255.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
REGS1_k127_8029585_2	1128421.JAGA01000002_gene314	9.223e-54	195.0	COG1131@1|root,COG1131@2|Bacteria,2NQPB@2323|unclassified Bacteria	2|Bacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
REGS1_k127_8081689_3	55207.KP22_09760	1.166e-155	496.0	COG1944@1|root,COG1944@2|Bacteria,1N4UP@1224|Proteobacteria,1SASC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	YcaO cyclodehydratase, ATP-ad Mg2+-binding	-	-	-	ko:K09136	-	-	-	-	ko00000,ko03009	-	-	-	ThiF,YcaO
REGS1_k127_8081689_6	314270.RB2083_1470	1.571e-14	85.0	COG1944@1|root,COG1944@2|Bacteria,1P453@1224|Proteobacteria	1224|Proteobacteria	S	ATP diphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8081689_1	631362.Thi970DRAFT_01055	5.936e-300	963.0	COG2114@1|root,COG3629@1|root,COG3899@1|root,COG2114@2|Bacteria,COG3629@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,1S0DF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc
REGS1_k127_8081689_5	1027396.LMOSA_13170	7.18e-29	126.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,4HEPH@91061|Bacilli,26JK8@186820|Listeriaceae	91061|Bacilli	G	Polysaccharide deacetylase	pgdA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
REGS1_k127_8081689_7	443143.GM18_2701	5.713e-07	53.0	COG3677@1|root,COG3677@2|Bacteria,1QYYF@1224|Proteobacteria	1224|Proteobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8081689_2	580332.Slit_2630	3.05e-226	703.0	COG0208@1|root,COG0208@2|Bacteria,1MWUS@1224|Proteobacteria,2VI7U@28216|Betaproteobacteria,44VEE@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
REGS1_k127_8081689_0	1235457.C404_18750	0.0	1462.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,2VJIV@28216|Betaproteobacteria,1K1JU@119060|Burkholderiaceae	28216|Betaproteobacteria	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC,Ribonuc_red_lgN
REGS1_k127_8117619_3	1121121.KB894312_gene3241	3.867e-11	63.0	2DREZ@1|root,33BFB@2|Bacteria,1UPXP@1239|Firmicutes,4IVCS@91061|Bacilli,2743X@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8117619_1	1485544.JQKP01000002_gene1483	1.686e-91	308.0	COG2518@1|root,COG2518@2|Bacteria,1RD6S@1224|Proteobacteria,2VJX3@28216|Betaproteobacteria,44VPV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Ribosomal RNA adenine dimethylase	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
REGS1_k127_8117619_0	395494.Galf_2852	1.864e-181	578.0	COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,2VHG1@28216|Betaproteobacteria,44VIB@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	TIGRFAM type I secretion outer membrane protein, TolC family	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
REGS1_k127_8117619_2	1007105.PT7_3158	2.162e-23	101.0	COG1088@1|root,COG1088@2|Bacteria,1MU5E@1224|Proteobacteria,2VJAD@28216|Betaproteobacteria,3T20E@506|Alcaligenaceae	28216|Betaproteobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd,dTDP_sugar_isom
REGS1_k127_8170517_13	580332.Slit_2168	3.002e-33	145.0	COG4585@1|root,COG4585@2|Bacteria,1QXNA@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K11617	ko02020,map02020	M00481,M00754	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA_3,PAS_4
REGS1_k127_8170517_16	1304284.L21TH_1689	9.499e-08	64.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,36EG9@31979|Clostridiaceae	186801|Clostridia	NT	chemotaxis	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
REGS1_k127_8170517_9	580332.Slit_2214	6.904e-94	312.0	COG2197@1|root,COG2197@2|Bacteria,1MWGM@1224|Proteobacteria,2VRK9@28216|Betaproteobacteria,44VX9@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_8170517_1	580332.Slit_1427	0.0	1234.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,2VHBJ@28216|Betaproteobacteria,44UYF@713636|Nitrosomonadales	28216|Betaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
REGS1_k127_8170517_3	1499967.BAYZ01000069_gene1853	4.096e-317	992.0	COG0474@1|root,COG0474@2|Bacteria,2NNSC@2323|unclassified Bacteria	2|Bacteria	P	Cation transporter/ATPase, N-terminus	pacL	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
REGS1_k127_8170517_2	1198452.Jab_2c01520	0.0	1056.0	COG2114@1|root,COG2203@1|root,COG2114@2|Bacteria,COG2203@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,4736W@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
REGS1_k127_8170517_11	1283284.AZUK01000001_gene2078	1.216e-59	209.0	COG2259@1|root,COG2259@2|Bacteria,1MZVP@1224|Proteobacteria,1S8UI@1236|Gammaproteobacteria,1Y6B3@135624|Aeromonadales	135624|Aeromonadales	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
REGS1_k127_8170517_6	1485544.JQKP01000001_gene872	1.914e-128	416.0	COG1741@1|root,COG1741@2|Bacteria,1MWIP@1224|Proteobacteria,2VHGK@28216|Betaproteobacteria,44VG8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
REGS1_k127_8170517_5	580332.Slit_1351	1.689e-130	422.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria,2VICP@28216|Betaproteobacteria,44VDG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Transcriptional regulator, LysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
REGS1_k127_8170517_0	580332.Slit_1663	0.0	1262.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,2VI2G@28216|Betaproteobacteria,44VJV@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
REGS1_k127_8170517_4	580332.Slit_1662	6.317e-145	462.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,2VH2K@28216|Betaproteobacteria,44VG0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Metallopeptidase family M24	map	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
REGS1_k127_8170517_10	375286.mma_1786	4.706e-70	246.0	COG3637@1|root,COG3637@2|Bacteria,1NG4D@1224|Proteobacteria,2W4Y9@28216|Betaproteobacteria,4770Q@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8170517_8	580332.Slit_0530	8.278e-103	344.0	COG0515@1|root,COG4252@1|root,COG0515@2|Bacteria,COG4252@2|Bacteria,1MV1P@1224|Proteobacteria,2VKJ8@28216|Betaproteobacteria	28216|Betaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	CHASE2,Pkinase
REGS1_k127_8170517_7	1000565.METUNv1_01462	1.351e-121	411.0	COG0664@1|root,COG2208@1|root,COG0664@2|Bacteria,COG2208@2|Bacteria,1MXJQ@1224|Proteobacteria,2VTSU@28216|Betaproteobacteria,2KX5A@206389|Rhodocyclales	206389|Rhodocyclales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,SpoIIE,cNMP_binding
REGS1_k127_8170517_15	292564.Cyagr_3432	2.604e-17	96.0	COG2172@1|root,COG2172@2|Bacteria,1GMR9@1117|Cyanobacteria,22TS9@167375|Cyanobium	1117|Cyanobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
REGS1_k127_8170517_14	1000565.METUNv1_01460	1.919e-27	115.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
REGS1_k127_8170517_12	580332.Slit_2461	2.806e-53	192.0	COG1647@1|root,COG1647@2|Bacteria,1MVZP@1224|Proteobacteria,2VN24@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Alpha/beta hydrolase family	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_6,Hydrolase_4
REGS1_k127_8282011_6	1121035.AUCH01000022_gene3197	8.18e-91	312.0	COG2206@1|root,COG2206@2|Bacteria,1R3VR@1224|Proteobacteria,2VMY5@28216|Betaproteobacteria,2KVPZ@206389|Rhodocyclales	206389|Rhodocyclales	T	Domain of unknown function (DUF3391)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3391,HD_5
REGS1_k127_8282011_7	1121935.AQXX01000113_gene1406	3.38e-68	240.0	COG5285@1|root,COG5285@2|Bacteria,1R9W1@1224|Proteobacteria,1S7VN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
REGS1_k127_8282011_0	580332.Slit_1976	0.0	1137.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,2VIP3@28216|Betaproteobacteria,44V5I@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
REGS1_k127_8282011_2	1485544.JQKP01000014_gene1874	9.175e-193	604.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,2VHC8@28216|Betaproteobacteria,44VIC@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
REGS1_k127_8282011_10	640081.Dsui_2211	8.356e-34	133.0	COG2009@1|root,COG2009@2|Bacteria,1RIGZ@1224|Proteobacteria,2VSEG@28216|Betaproteobacteria,2KWKD@206389|Rhodocyclales	206389|Rhodocyclales	C	COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
REGS1_k127_8282011_8	1485544.JQKP01000001_gene1294	1.453e-43	162.0	COG2142@1|root,COG2142@2|Bacteria,1MZR9@1224|Proteobacteria,2VSJN@28216|Betaproteobacteria,44W15@713636|Nitrosomonadales	28216|Betaproteobacteria	C	TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein	sdhD	-	-	ko:K00242	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
REGS1_k127_8282011_1	580332.Slit_1839	0.0	1069.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,44V9G@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily	sdhA	GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
REGS1_k127_8282011_4	314345.SPV1_05153	4.67e-145	488.0	COG2197@1|root,COG2203@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria	1224|Proteobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,GAF,GAF_2,HD,HD_5,PAS,PAS_4,PAS_9,Response_reg
REGS1_k127_8282011_5	580332.Slit_1838	7.048e-140	445.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,2VIKC@28216|Betaproteobacteria,44VM4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family	sdhB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
REGS1_k127_8282011_9	1116472.MGMO_15c00080	1.939e-37	148.0	COG2852@1|root,COG2852@2|Bacteria,1N0QU@1224|Proteobacteria,1SA4A@1236|Gammaproteobacteria,1XFUA@135618|Methylococcales	135618|Methylococcales	L	Protein of unknown function (DUF559)	-	-	2.1.1.72	ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF559
REGS1_k127_8282011_11	580332.Slit_1837	7.128e-19	94.0	COG2938@1|root,COG2938@2|Bacteria,1N7P4@1224|Proteobacteria,2VY7W@28216|Betaproteobacteria,44W4H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Flavinator of succinate dehydrogenase	-	-	-	ko:K09159	-	-	-	-	ko00000,ko02048	-	-	-	Sdh5
REGS1_k127_8282011_3	580332.Slit_1836	1.04e-149	476.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,2VIJF@28216|Betaproteobacteria,44VKZ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
REGS1_k127_8286347_13	1429916.X566_01630	1.439e-16	95.0	2A2JU@1|root,30QXU@2|Bacteria,1N7N4@1224|Proteobacteria,2TTU2@28211|Alphaproteobacteria,3JR2N@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	MA20_08245	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8286347_1	580332.Slit_0066	1.473e-279	864.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,2VJ8B@28216|Betaproteobacteria,44V8G@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
REGS1_k127_8286347_9	1485544.JQKP01000001_gene904	3.738e-58	203.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,2VSEZ@28216|Betaproteobacteria,44VUX@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Belongs to the P(II) protein family	glnK	-	-	ko:K04752	-	-	-	-	ko00000	-	-	-	P-II
REGS1_k127_8286347_6	1230343.CANP01000021_gene1423	2.554e-72	257.0	COG2067@1|root,COG2067@2|Bacteria	2|Bacteria	I	long-chain fatty acid transporting porin activity	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
REGS1_k127_8286347_7	580332.Slit_0064	4.734e-66	234.0	2C5U9@1|root,30FF7@2|Bacteria,1N2U0@1224|Proteobacteria,2WIIE@28216|Betaproteobacteria,44VV4@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial protein of unknown function (Gcw_chp)	-	-	-	-	-	-	-	-	-	-	-	-	Gcw_chp
REGS1_k127_8286347_12	395494.Galf_0068	3.536e-23	100.0	COG2960@1|root,COG2960@2|Bacteria,1N7AH@1224|Proteobacteria,2VVR4@28216|Betaproteobacteria,44W3N@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Membrane fusogenic activity	yqiC	-	-	ko:K09806	-	-	-	-	ko00000	-	-	-	BMFP
REGS1_k127_8286347_2	580332.Slit_0062	5.521e-271	839.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,2VHRV@28216|Betaproteobacteria,44V3K@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
REGS1_k127_8286347_3	580332.Slit_2960	2.498e-191	602.0	COG0418@1|root,COG0418@2|Bacteria,1MUYP@1224|Proteobacteria,2VH6F@28216|Betaproteobacteria,44V1G@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
REGS1_k127_8286347_5	580332.Slit_2956	1.215e-95	315.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,2VR65@28216|Betaproteobacteria,44VMU@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial transferase hexapeptide (six repeats)	yrdA	-	-	-	-	-	-	-	-	-	-	-	Hexapep
REGS1_k127_8286347_11	1485544.JQKP01000007_gene2041	6.682e-37	142.0	COG5626@1|root,COG5626@2|Bacteria,1N8QB@1224|Proteobacteria,2VWJM@28216|Betaproteobacteria,44W22@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF2288)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2288
REGS1_k127_8286347_14	580332.Slit_2199	4.02e-05	49.0	COG0820@1|root,COG0820@2|Bacteria,1Q0HH@1224|Proteobacteria,2VMGJ@28216|Betaproteobacteria,44VGY@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Belongs to the radical SAM superfamily. RlmN family	rlmN_2	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
REGS1_k127_8286347_8	395494.Galf_0063	3.179e-61	214.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VSIG@28216|Betaproteobacteria,44WGS@713636|Nitrosomonadales	28216|Betaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	fkpA	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
REGS1_k127_8286347_0	1485544.JQKP01000007_gene2011	0.0	2091.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2VHYQ@28216|Betaproteobacteria,44V3A@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Vitamin B12 dependent methionine synthase activation region	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
REGS1_k127_8286347_4	580332.Slit_0003	1.823e-155	495.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,2VI8N@28216|Betaproteobacteria,44WB9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
REGS1_k127_8356700_2	1485544.JQKP01000012_gene2150	3.982e-292	910.0	COG1643@1|root,COG1643@2|Bacteria,1MUEQ@1224|Proteobacteria,2VI3R@28216|Betaproteobacteria,44VDV@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
REGS1_k127_8356700_14	395494.Galf_0431	1.61e-107	362.0	2AFYG@1|root,31628@2|Bacteria,1PWQT@1224|Proteobacteria,2WC9D@28216|Betaproteobacteria,44VMT@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8356700_1	580332.Slit_0442	2.173e-297	925.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,1MV34@1224|Proteobacteria,2VHQQ@28216|Betaproteobacteria,44VNP@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	kefB	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
REGS1_k127_8356700_7	395494.Galf_0275	2.875e-151	484.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,1MUXD@1224|Proteobacteria,2VI24@28216|Betaproteobacteria,44V7U@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the SIS family. GutQ KpsF subfamily	kdsD	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
REGS1_k127_8356700_18	395494.Galf_0276	1.591e-83	280.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,2VRQX@28216|Betaproteobacteria,44VQ3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family	kdsC	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase,Hydrolase_3
REGS1_k127_8356700_25	580332.Slit_0439	5.138e-50	187.0	COG3117@1|root,COG3117@2|Bacteria,1R5UK@1224|Proteobacteria,2VU37@28216|Betaproteobacteria,44VWE@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Lipopolysaccharide-assembly, LptC-related	lptC	-	-	ko:K11719	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	LptC
REGS1_k127_8356700_26	1485544.JQKP01000001_gene1183	7.299e-46	172.0	COG1934@1|root,COG1934@2|Bacteria,1N776@1224|Proteobacteria,2VSI4@28216|Betaproteobacteria,44VXS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
REGS1_k127_8356700_12	580332.Slit_0437	1.145e-131	425.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,2VH29@28216|Betaproteobacteria,44V0H@713636|Nitrosomonadales	28216|Betaproteobacteria	S	ABC transporter	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
REGS1_k127_8356700_5	580332.Slit_0436	8.026e-201	635.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,2VIEV@28216|Betaproteobacteria,44UZ8@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
REGS1_k127_8356700_27	1485544.JQKP01000001_gene1180	3.176e-42	156.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,2VU5H@28216|Betaproteobacteria,44W0Q@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM sigma 54 modulation protein ribosomal protein S30EA	raiA	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosomal_S30AE
REGS1_k127_8356700_21	580332.Slit_0434	6.101e-66	228.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,2VRDH@28216|Betaproteobacteria,44VUH@713636|Nitrosomonadales	28216|Betaproteobacteria	GT	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
REGS1_k127_8356700_10	580332.Slit_0433	1.93e-140	460.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,2VJCH@28216|Betaproteobacteria,44V87@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
REGS1_k127_8356700_11	580332.Slit_0432	1.008e-132	427.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,2VIH5@28216|Betaproteobacteria,44V0U@713636|Nitrosomonadales	28216|Betaproteobacteria	S	P-loop ATPase protein family	yhbJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
REGS1_k127_8356700_24	580332.Slit_0431	3.018e-51	186.0	COG5341@1|root,COG5341@2|Bacteria,1N1PN@1224|Proteobacteria,2VUW8@28216|Betaproteobacteria,44VY7@713636|Nitrosomonadales	28216|Betaproteobacteria	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
REGS1_k127_8356700_20	580332.Slit_0430	1.183e-80	274.0	COG4769@1|root,COG4769@2|Bacteria,1RJIB@1224|Proteobacteria,2VRM1@28216|Betaproteobacteria,44VVI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Heptaprenyl diphosphate synthase component I	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
REGS1_k127_8356700_13	580332.Slit_0429	3.428e-113	367.0	COG0163@1|root,COG0163@2|Bacteria,1RA0P@1224|Proteobacteria,2VIWQ@28216|Betaproteobacteria,44VAK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
REGS1_k127_8356700_16	322710.Avin_01350	1.734e-93	313.0	COG3655@1|root,COG3655@2|Bacteria,1RBPK@1224|Proteobacteria,1S22Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
REGS1_k127_8356700_22	1123487.KB892857_gene2506	4.855e-65	230.0	28IT1@1|root,2Z8S1@2|Bacteria,1PUT6@1224|Proteobacteria,2VTT1@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
REGS1_k127_8356700_0	1121035.AUCH01000022_gene3191	0.0	1024.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,2VK7T@28216|Betaproteobacteria,2KUKS@206389|Rhodocyclales	206389|Rhodocyclales	IQ	Phosphate acyltransferases	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,Acyltransferase
REGS1_k127_8356700_6	580332.Slit_0462	6.979e-161	521.0	COG0477@1|root,COG0477@2|Bacteria,1QUAG@1224|Proteobacteria,2WHA4@28216|Betaproteobacteria	28216|Betaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	ko:K08227	-	-	-	-	ko00000,ko02000	2.A.1.42	-	-	MFS_1
REGS1_k127_8356700_17	159087.Daro_0407	1.165e-89	302.0	COG0682@1|root,COG0682@2|Bacteria,1MVRP@1224|Proteobacteria,2W2JT@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	-	-	-	-	-	-	-	-	-	LGT
REGS1_k127_8356700_3	159087.Daro_0409	3.329e-242	759.0	COG1964@1|root,COG1964@2|Bacteria,1QE02@1224|Proteobacteria,2VPAH@28216|Betaproteobacteria	28216|Betaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_8356700_8	1038869.AXAN01000006_gene968	1.225e-148	486.0	COG0477@1|root,COG2814@2|Bacteria,1MU1I@1224|Proteobacteria,2VJGS@28216|Betaproteobacteria,1K0ZN@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Major facilitator superfamily	emrB	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
REGS1_k127_8356700_15	358220.C380_12495	1.209e-96	332.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,2VHA2@28216|Betaproteobacteria,4AAZA@80864|Comamonadaceae	28216|Betaproteobacteria	V	secretion protein HlyD family	emrA	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD,HlyD_3,HlyD_D23
REGS1_k127_8356700_9	580332.Slit_0461	1.35e-141	453.0	COG4535@1|root,COG4535@2|Bacteria,1QTU8@1224|Proteobacteria,2VIU8@28216|Betaproteobacteria,44VD2@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC
REGS1_k127_8356700_23	395494.Galf_0596	1.212e-58	208.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,2VSHV@28216|Betaproteobacteria,44VUQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
REGS1_k127_8356700_4	1485544.JQKP01000001_gene1242	1.235e-227	712.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,2VHQM@28216|Betaproteobacteria,44V1C@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
REGS1_k127_8356700_19	1120999.JONM01000002_gene906	6.374e-81	279.0	COG1741@1|root,COG1741@2|Bacteria,1MVSW@1224|Proteobacteria,2VHPA@28216|Betaproteobacteria,2KR50@206351|Neisseriales	206351|Neisseriales	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
REGS1_k127_8360882_9	580332.Slit_2222	2.578e-64	224.0	COG1721@1|root,COG1721@2|Bacteria,1R3QD@1224|Proteobacteria,2VN9P@28216|Betaproteobacteria,44WBQ@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
REGS1_k127_8360882_0	580332.Slit_2223	5.678e-247	778.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,2VHZP@28216|Betaproteobacteria,44WEH@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	2.3.2.13	ko:K22452	-	-	-	-	ko00000,ko01000	-	-	-	DUF3488,DUF4129,Transglut_core
REGS1_k127_8360882_8	580332.Slit_2224	2.186e-79	267.0	COG0720@1|root,COG0720@2|Bacteria,1RETG@1224|Proteobacteria,2VRBN@28216|Betaproteobacteria,44VRF@713636|Nitrosomonadales	28216|Betaproteobacteria	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
REGS1_k127_8360882_4	580332.Slit_1559	2.616e-98	332.0	COG2199@1|root,COG3706@2|Bacteria,1REIE@1224|Proteobacteria,2W3W6@28216|Betaproteobacteria,44WHE@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,cNMP_binding
REGS1_k127_8360882_10	349521.HCH_06679	4.626e-27	124.0	2E3UE@1|root,32YRS@2|Bacteria,1N75A@1224|Proteobacteria,1S9W5@1236|Gammaproteobacteria,1XM11@135619|Oceanospirillales	135619|Oceanospirillales	S	Protein of unknown function (DUF2799)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2799
REGS1_k127_8360882_5	686340.Metal_2530	1.812e-96	319.0	COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria,1XG99@135618|Methylococcales	135618|Methylococcales	C	Belongs to the WrbA family	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
REGS1_k127_8360882_1	331113.SNE_B24410	6.57e-208	661.0	COG0058@1|root,COG0058@2|Bacteria,2JFEH@204428|Chlamydiae	204428|Chlamydiae	G	Carbohydrate phosphorylase	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
REGS1_k127_8360882_7	497321.C664_10373	3.513e-80	272.0	COG3124@1|root,COG3124@2|Bacteria,1MZ59@1224|Proteobacteria,2VSFW@28216|Betaproteobacteria,2KWV1@206389|Rhodocyclales	206389|Rhodocyclales	S	Acyl carrier protein phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	ACP_PD
REGS1_k127_8360882_6	395494.Galf_2290	4.91e-90	300.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VJCP@28216|Betaproteobacteria,44V2R@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SNARE associated Golgi protein	dedA	-	-	ko:K03975	-	-	-	-	ko00000	-	-	-	SNARE_assoc
REGS1_k127_8360882_2	1485544.JQKP01000005_gene351	1.031e-163	518.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,2VHZG@28216|Betaproteobacteria,44V8I@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
REGS1_k127_8360882_3	1485544.JQKP01000005_gene350	1.299e-108	354.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,2VHKD@28216|Betaproteobacteria,44VEI@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD-TM1,SecD_SecF,Sec_GG
REGS1_k127_8364070_1	580332.Slit_0524	1.758e-112	369.0	COG0603@1|root,COG0603@2|Bacteria,1MU5V@1224|Proteobacteria,2VHY3@28216|Betaproteobacteria,44V5Y@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
REGS1_k127_8364070_2	1485544.JQKP01000014_gene1859	6.702e-111	361.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2VGZ7@28216|Betaproteobacteria,44VIV@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
REGS1_k127_8364070_4	1485544.JQKP01000014_gene1860	5.222e-57	207.0	COG1729@1|root,COG1729@2|Bacteria,1MUSV@1224|Proteobacteria,2VIPC@28216|Betaproteobacteria,44VUU@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri,YfiO
REGS1_k127_8364070_7	395494.Galf_2583	1.458e-51	187.0	COG2885@1|root,COG2885@2|Bacteria,1MZTV@1224|Proteobacteria,2VSP6@28216|Betaproteobacteria,44W03@713636|Nitrosomonadales	28216|Betaproteobacteria	M	OmpA family	pal	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
REGS1_k127_8364070_0	580332.Slit_0520	6.176e-184	583.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,2VH9R@28216|Betaproteobacteria,44V5U@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
REGS1_k127_8364070_8	1485544.JQKP01000014_gene1863	2.767e-42	166.0	COG3064@1|root,COG3064@2|Bacteria,1RKZU@1224|Proteobacteria,2WGP5@28216|Betaproteobacteria,44VYW@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TolA C-terminal	tolA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	TonB_2
REGS1_k127_8364070_6	580332.Slit_0518	4.6e-52	187.0	COG0848@1|root,COG0848@2|Bacteria,1RGWR@1224|Proteobacteria,2VT20@28216|Betaproteobacteria,44VVP@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM Biopolymer transport protein ExbD TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
REGS1_k127_8364070_3	580332.Slit_0517	3.523e-108	353.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,2VJPW@28216|Betaproteobacteria,44VN7@713636|Nitrosomonadales	28216|Betaproteobacteria	U	PFAM MotA TolQ ExbB proton channel	tolQ	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
REGS1_k127_8364070_5	580332.Slit_0516	3.427e-53	192.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,2VUEV@28216|Betaproteobacteria,44VXM@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Thioesterase-like superfamily	ybgC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
REGS1_k127_8435281_7	580332.Slit_1462	8.431e-161	510.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,2VJMF@28216|Betaproteobacteria,44V0B@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
REGS1_k127_8435281_11	580332.Slit_1461	1.48e-81	272.0	COG0780@1|root,COG0780@2|Bacteria,1MW0M@1224|Proteobacteria,2VINU@28216|Betaproteobacteria,44VQN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)	queF	-	1.7.1.13	ko:K06879,ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF,QueF_N
REGS1_k127_8435281_13	580332.Slit_2753	1.667e-40	157.0	COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,2VW9W@28216|Betaproteobacteria,44WPG@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
REGS1_k127_8435281_3	580332.Slit_1506	2.932e-233	726.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,2VINP@28216|Betaproteobacteria,44VDU@713636|Nitrosomonadales	28216|Betaproteobacteria	E	ACT domain	lysC	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
REGS1_k127_8435281_2	580332.Slit_1505	7.091e-270	839.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,2VIGF@28216|Betaproteobacteria,44VNW@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DHH family	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
REGS1_k127_8435281_6	580332.Slit_1504	1.225e-171	547.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria	28216|Betaproteobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
REGS1_k127_8435281_5	1163617.SCD_n01826	1.648e-190	599.0	COG1186@1|root,COG1186@2|Bacteria,1MUAW@1224|Proteobacteria,2VJ6C@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
REGS1_k127_8435281_4	580332.Slit_1502	7.158e-206	649.0	2CG46@1|root,2Z7W3@2|Bacteria,1NFW3@1224|Proteobacteria,2VN3X@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8435281_8	580332.Slit_1501	2.102e-117	381.0	28KTK@1|root,2ZAAP@2|Bacteria,1RCI8@1224|Proteobacteria,2VQ6W@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8435281_0	580332.Slit_1500	0.0	1474.0	COG1196@1|root,COG1196@2|Bacteria,1NGZ2@1224|Proteobacteria,2VIWY@28216|Betaproteobacteria	28216|Betaproteobacteria	D	SMC domain protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_29,SMC_N
REGS1_k127_8435281_1	1485544.JQKP01000001_gene974	9.138e-282	870.0	COG1190@1|root,COG1190@2|Bacteria,1MX1V@1224|Proteobacteria,2VH1A@28216|Betaproteobacteria,44V4E@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM tRNA synthetase class II (D K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
REGS1_k127_8435281_10	1485544.JQKP01000001_gene973	1.192e-87	294.0	COG0664@1|root,COG0664@2|Bacteria,1R6BV@1224|Proteobacteria,2VN3A@28216|Betaproteobacteria,44VNG@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, cAMP Regulatory protein	nnr	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
REGS1_k127_8435281_15	1223521.BBJX01000004_gene2547	4.34e-26	109.0	2EGD6@1|root,33A4Z@2|Bacteria,1N733@1224|Proteobacteria,2VVS2@28216|Betaproteobacteria,4AFBH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892
REGS1_k127_8435281_12	96561.Dole_2192	6.888e-73	256.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,42R2E@68525|delta/epsilon subdivisions,2WMYN@28221|Deltaproteobacteria,2MJPF@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
REGS1_k127_8435281_9	395494.Galf_1644	1.184e-112	372.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria	1224|Proteobacteria	C	Formate acetyltransferase	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
REGS1_k127_8700293_0	1348657.M622_14850	3.471e-78	266.0	COG4657@1|root,COG4657@2|Bacteria,1MU8X@1224|Proteobacteria,2VH0C@28216|Betaproteobacteria,2KUIH@206389|Rhodocyclales	206389|Rhodocyclales	C	Part of a membrane complex involved in electron transport	-	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
REGS1_k127_8700293_1	580332.Slit_2540	1.324e-41	156.0	COG1188@1|root,COG1188@2|Bacteria,1MZR6@1224|Proteobacteria,2VTY8@28216|Betaproteobacteria,44WID@713636|Nitrosomonadales	28216|Betaproteobacteria	J	SMART RNA-binding S4 domain protein	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
REGS1_k127_8700293_5	351607.Acel_1568	5.737e-17	96.0	COG1372@1|root,COG1372@2|Bacteria	2|Bacteria	L	intein-mediated protein splicing	rtcB	-	1.17.4.1,6.5.1.3	ko:K00525,ko:K14415	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03016,ko03400	-	-	-	Intein_splicing,LAGLIDADG_2,LAGLIDADG_3,Phage_Mu_F,Phage_portal,RtcB
REGS1_k127_8700293_4	1042209.HK44_008195	5.504e-17	82.0	COG3157@1|root,COG3157@2|Bacteria	2|Bacteria	S	Type VI secretion system effector, Hcp	-	-	-	-	-	-	-	-	-	-	-	-	Pyocin_S
REGS1_k127_8700293_7	991.IW20_15035	1.761e-11	68.0	2DRCY@1|root,33B91@2|Bacteria,4P9CQ@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8700293_3	399741.Spro_4077	1.664e-20	107.0	COG3210@1|root,COG3210@2|Bacteria,1MX2K@1224|Proteobacteria,1RNRK@1236|Gammaproteobacteria,401W8@613|Serratia	1236|Gammaproteobacteria	U	Large exoproteins involved in heme utilization or adhesion	-	-	-	ko:K15125	ko05133,map05133	-	-	-	ko00000,ko00001,ko00536	-	-	-	ESPR,Fil_haemagg,Fil_haemagg_2,Haemagg_act,PT-VENN
REGS1_k127_8700293_6	179408.Osc7112_2877	1.931e-12	72.0	2EHXP@1|root,33BP6@2|Bacteria,1GE1A@1117|Cyanobacteria,1HFI7@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8700293_10	1442599.JAAN01000035_gene607	0.0002151	48.0	2BNT6@1|root,32HGS@2|Bacteria,1PJR2@1224|Proteobacteria,1TCNJ@1236|Gammaproteobacteria,1X9K9@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8700293_8	1151127.KB906337_gene1203	2.785e-09	61.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	RHS,RHS_repeat,Tox-HNH-EHHH
REGS1_k127_8700293_9	1442599.JAAN01000035_gene608	1.39e-05	52.0	2BSQF@1|root,32MTA@2|Bacteria,1QGI3@1224|Proteobacteria,1TDXV@1236|Gammaproteobacteria,1XB5P@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8735607_2	1485544.JQKP01000014_gene1891	1.47e-117	382.0	COG0128@1|root,COG0128@2|Bacteria,1MWMK@1224|Proteobacteria,2VGZF@28216|Betaproteobacteria,44VC3@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin,EPSP_synthase
REGS1_k127_8735607_1	580332.Slit_2062	6.293e-136	437.0	COG0287@1|root,COG0287@2|Bacteria,1QTZA@1224|Proteobacteria,2VIS1@28216|Betaproteobacteria,44VG3@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Prephenate dehydrogenase	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
REGS1_k127_8735607_3	1163617.SCD_n02743	6.964e-82	279.0	2905E@1|root,2ZMVA@2|Bacteria,1REVI@1224|Proteobacteria,2WHYR@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8735607_0	1485544.JQKP01000003_gene152	5.387e-293	909.0	COG4166@1|root,COG4166@2|Bacteria,1R87R@1224|Proteobacteria,2VKFJ@28216|Betaproteobacteria,44W8T@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
REGS1_k127_8829765_15	580332.Slit_2614	6.416e-58	204.0	COG0607@1|root,COG0607@2|Bacteria,1MZ83@1224|Proteobacteria,2VU3D@28216|Betaproteobacteria,44VX6@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Rhodanese Homology Domain	glpE	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
REGS1_k127_8829765_19	1485544.JQKP01000012_gene2137	7.399e-33	132.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,2VU2J@28216|Betaproteobacteria,44W0F@713636|Nitrosomonadales	28216|Betaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
REGS1_k127_8829765_16	580332.Slit_2612	4.676e-56	199.0	COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,2VQ1Q@28216|Betaproteobacteria,44VTN@713636|Nitrosomonadales	28216|Betaproteobacteria	U	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA	secB	-	-	ko:K03071	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03110	3.A.5	-	-	SecB
REGS1_k127_8829765_18	395494.Galf_0223	6.258e-44	167.0	COG3807@1|root,COG3807@2|Bacteria,1MZIA@1224|Proteobacteria,2VUTD@28216|Betaproteobacteria,44W2W@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_4
REGS1_k127_8829765_8	1485544.JQKP01000012_gene2134	2.288e-145	467.0	COG0240@1|root,COG0240@2|Bacteria,1MUU3@1224|Proteobacteria,2VJ91@28216|Betaproteobacteria,44VMG@713636|Nitrosomonadales	28216|Betaproteobacteria	I	PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
REGS1_k127_8829765_13	1485544.JQKP01000002_gene1553	7.451e-71	242.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,2VR5W@28216|Betaproteobacteria,44VUM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
REGS1_k127_8829765_6	1198452.Jab_2c30310	7.769e-167	577.0	COG0642@1|root,COG0715@1|root,COG5002@1|root,COG0715@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria,472D0@75682|Oxalobacteraceae	28216|Betaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,Response_reg
REGS1_k127_8829765_10	580332.Slit_2590	8.149e-85	287.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,2VSPK@28216|Betaproteobacteria,44VV3@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM Phosphoribosyltransferase	comF	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
REGS1_k127_8829765_5	395494.Galf_0244	4.805e-174	552.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,2VHZZ@28216|Betaproteobacteria,44VIK@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
REGS1_k127_8829765_4	580332.Slit_2588	6.098e-190	598.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,2VH25@28216|Betaproteobacteria,44VN1@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_8829765_17	243365.CV_4377	1.283e-46	179.0	COG2267@1|root,COG2267@2|Bacteria,1N2R9@1224|Proteobacteria,2VRME@28216|Betaproteobacteria,2KTUZ@206351|Neisseriales	206351|Neisseriales	I	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters	bioH	-	3.1.1.85	ko:K02170	ko00780,ko01100,map00780,map01100	M00572	R09725	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
REGS1_k127_8829765_7	580332.Slit_2586	6.848e-147	469.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,2VJP9@28216|Betaproteobacteria,44VH3@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11
REGS1_k127_8829765_9	580332.Slit_2585	6.647e-92	308.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,2VR4C@28216|Betaproteobacteria,44VS6@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
REGS1_k127_8829765_14	580332.Slit_2583	6.472e-63	221.0	COG1999@1|root,COG1999@2|Bacteria,1RHJ8@1224|Proteobacteria,2VR3M@28216|Betaproteobacteria,44VTT@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM electron transport protein SCO1 SenC	-	-	-	ko:K07152	-	-	-	-	ko00000,ko03029	-	-	-	SCO1-SenC
REGS1_k127_8829765_3	580332.Slit_2582	1.608e-197	632.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,2VIXT@28216|Betaproteobacteria,44VY8@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
REGS1_k127_8829765_11	580332.Slit_2581	2.823e-82	278.0	COG2197@1|root,COG2197@2|Bacteria,1P4TD@1224|Proteobacteria,2VMX4@28216|Betaproteobacteria,44VVH@713636|Nitrosomonadales	28216|Betaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
REGS1_k127_8829765_0	395494.Galf_0252	0.0	1094.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,2VHJV@28216|Betaproteobacteria,44VA1@713636|Nitrosomonadales	28216|Betaproteobacteria	D	PFAM cell divisionFtsK SpoIIIE	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
REGS1_k127_8829765_12	580332.Slit_2579	9.62e-75	258.0	COG2834@1|root,COG2834@2|Bacteria,1PXDV@1224|Proteobacteria,2VNNH@28216|Betaproteobacteria,44VR2@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
REGS1_k127_8829765_1	580332.Slit_2578	9.871e-243	754.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,2VHN9@28216|Betaproteobacteria,44V6I@713636|Nitrosomonadales	28216|Betaproteobacteria	L	MgsA AAA+ ATPase C terminal	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
REGS1_k127_8829765_2	580332.Slit_2576	1.012e-225	706.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,2VHJJ@28216|Betaproteobacteria,44V1U@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
REGS1_k127_883138_0	1485544.JQKP01000010_gene819	0.0	1037.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,2VIE5@28216|Betaproteobacteria,44V30@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs	rne	-	3.1.26.12	ko:K08300	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
REGS1_k127_883138_4	580332.Slit_1760	8.327e-74	251.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,2VSKW@28216|Betaproteobacteria,44VTI@713636|Nitrosomonadales	28216|Betaproteobacteria	T	PFAM Protein-tyrosine phosphatase, low molecular weight	ptpA	GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
REGS1_k127_883138_10	1114970.PSF113_4078a	4.266e-46	171.0	2C3U0@1|root,32UBK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2691
REGS1_k127_883138_1	580332.Slit_1394	1.372e-248	772.0	COG1282@1|root,COG1282@2|Bacteria,1MUP4@1224|Proteobacteria,2VIDR@28216|Betaproteobacteria,44VMQ@713636|Nitrosomonadales	28216|Betaproteobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	pntB	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
REGS1_k127_883138_9	580332.Slit_1393	8.315e-47	169.0	COG3288@1|root,COG3288@2|Bacteria,1MZ3E@1224|Proteobacteria,2VSM2@28216|Betaproteobacteria	28216|Betaproteobacteria	C	NADP transhydrogenase	pntAb	-	1.6.1.1,1.6.1.2	ko:K00322,ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
REGS1_k127_883138_2	580332.Slit_1392	5.672e-197	620.0	COG3288@1|root,COG3288@2|Bacteria,1MVXU@1224|Proteobacteria,2VJZN@28216|Betaproteobacteria,44VIH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Alanine dehydrogenase/PNT, N-terminal domain	pntAA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
REGS1_k127_883138_12	713587.THITH_00875	1.849e-11	72.0	2DBSQ@1|root,2ZATE@2|Bacteria,1N58C@1224|Proteobacteria,1SAPH@1236|Gammaproteobacteria,1X12X@135613|Chromatiales	135613|Chromatiales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_883138_8	546267.NEIPOLOT_02272	4.452e-50	186.0	COG2229@1|root,COG2229@2|Bacteria,1PYIA@1224|Proteobacteria,2VITQ@28216|Betaproteobacteria,2KQHA@206351|Neisseriales	206351|Neisseriales	S	GTP-binding domain protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
REGS1_k127_883138_3	1123504.JQKD01000117_gene390	1.283e-97	336.0	COG1120@1|root,COG2453@1|root,COG1120@2|Bacteria,COG2453@2|Bacteria,1P0GN@1224|Proteobacteria,2VNDH@28216|Betaproteobacteria,4AC63@80864|Comamonadaceae	28216|Betaproteobacteria	HPT	PFAM Dual specificity protein phosphatase	-	-	3.1.3.16,3.1.3.48	ko:K14165	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	ABC_tran,DSPc
REGS1_k127_883138_7	365044.Pnap_0368	2.565e-55	196.0	COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae	28216|Betaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_883138_6	365044.Pnap_0368	7.759e-59	207.0	COG3829@1|root,COG3829@2|Bacteria,1REUB@1224|Proteobacteria,2VRFH@28216|Betaproteobacteria,4AE2K@80864|Comamonadaceae	28216|Betaproteobacteria	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_883138_11	365044.Pnap_0367	1.16e-27	116.0	COG2018@1|root,COG2018@2|Bacteria	2|Bacteria	K	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
REGS1_k127_883138_5	392500.Swoo_0575	5.027e-72	258.0	COG1018@1|root,COG1018@2|Bacteria,1QXF0@1224|Proteobacteria,1T3A3@1236|Gammaproteobacteria,2Q8UF@267890|Shewanellaceae	1236|Gammaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
REGS1_k127_8833784_24	580332.Slit_2212	8.395e-71	255.0	COG0457@1|root,COG0457@2|Bacteria,1P464@1224|Proteobacteria,2VMYZ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF560)	-	-	-	-	-	-	-	-	-	-	-	-	DUF560,TPR_19
REGS1_k127_8833784_26	653733.Selin_0214	2.341e-33	139.0	COG0810@1|root,COG4254@1|root,COG0810@2|Bacteria,COG4254@2|Bacteria	2|Bacteria	UW	PFAM FecR protein	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	FecR,TonB_2,TonB_C
REGS1_k127_8833784_20	580332.Slit_2775	1.374e-109	360.0	COG1028@1|root,COG1028@2|Bacteria,1P9R4@1224|Proteobacteria,2VUQP@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
REGS1_k127_8833784_22	1288494.EBAPG3_20620	8.638e-87	290.0	COG1544@1|root,COG1544@2|Bacteria,1RJ55@1224|Proteobacteria,2VR5Q@28216|Betaproteobacteria,372T2@32003|Nitrosomonadales	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	CSD,Ribosomal_S30AE
REGS1_k127_8833784_27	580332.Slit_2152	1.116e-22	102.0	2E1DK@1|root,32WSU@2|Bacteria,1N3VJ@1224|Proteobacteria,2VV0D@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8833784_18	1485544.JQKP01000005_gene367	3.253e-122	395.0	COG1187@1|root,COG1187@2|Bacteria,1MXQE@1224|Proteobacteria,2VI7P@28216|Betaproteobacteria,44VGU@713636|Nitrosomonadales	28216|Betaproteobacteria	J	S4 RNA-binding domain	rluF	-	5.4.99.21	ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
REGS1_k127_8833784_23	580332.Slit_0464	3.969e-86	290.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,2VIBH@28216|Betaproteobacteria	28216|Betaproteobacteria	U	UPF0056 inner membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
REGS1_k127_8833784_11	580332.Slit_0466	1.814e-181	582.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,2VH1I@28216|Betaproteobacteria,44VMW@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
REGS1_k127_8833784_13	395494.Galf_2683	6.415e-160	514.0	COG5008@1|root,COG5008@2|Bacteria,1QTTX@1224|Proteobacteria,2VIWS@28216|Betaproteobacteria,44V5T@713636|Nitrosomonadales	28216|Betaproteobacteria	NU	PFAM type II secretion system protein E	-	-	-	ko:K02670	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
REGS1_k127_8833784_6	1485544.JQKP01000002_gene1584	7.059e-223	692.0	COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,2VHGI@28216|Betaproteobacteria,44V7P@713636|Nitrosomonadales	28216|Betaproteobacteria	G	TIGRFAM fructose-bisphosphate aldolase, class II, Calvin cycle subtype	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
REGS1_k127_8833784_4	580332.Slit_0017	4.828e-257	797.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,2VHN5@28216|Betaproteobacteria,44VCT@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the pyruvate kinase family	pykA	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
REGS1_k127_8833784_5	1485544.JQKP01000002_gene1582	6.075e-227	706.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,2VHJK@28216|Betaproteobacteria,44VJU@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the phosphoglycerate kinase family	pgk	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
REGS1_k127_8833784_9	1236959.BAMT01000002_gene2157	5.755e-198	619.0	COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,2VHHG@28216|Betaproteobacteria,2KMB2@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
REGS1_k127_8833784_1	580332.Slit_0014	0.0	1303.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,2VHNX@28216|Betaproteobacteria,44VJX@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
REGS1_k127_8833784_7	1485544.JQKP01000001_gene887	2.377e-216	679.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,2VJ5M@28216|Betaproteobacteria,44V7E@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
REGS1_k127_8833784_2	395494.Galf_0424	2.585e-299	926.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,2VI6G@28216|Betaproteobacteria,44V98@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	lpdA	GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim
REGS1_k127_8833784_3	1000565.METUNv1_00702	2.018e-268	837.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,2VHQ1@28216|Betaproteobacteria,2KV9Y@206389|Rhodocyclales	206389|Rhodocyclales	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
REGS1_k127_8833784_8	580332.Slit_2063	3.859e-204	637.0	COG2876@1|root,COG2876@2|Bacteria,1QVAD@1224|Proteobacteria,2VH85@28216|Betaproteobacteria,44VHR@713636|Nitrosomonadales	28216|Betaproteobacteria	E	NeuB family	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
REGS1_k127_8833784_12	580332.Slit_2064	6.712e-181	572.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,2VIPQ@28216|Betaproteobacteria,44V48@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC2	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
REGS1_k127_8833784_17	243365.CV_2355	9.96e-126	414.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1MU60@1224|Proteobacteria,2VJEV@28216|Betaproteobacteria,2KPE8@206351|Neisseriales	206351|Neisseriales	E	chorismate mutase	pheA	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
REGS1_k127_8833784_10	580332.Slit_2067	6.219e-198	621.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VH5M@28216|Betaproteobacteria,44VKB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
REGS1_k127_8833784_0	580332.Slit_2068	0.0	1537.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,2VJ5Q@28216|Betaproteobacteria,44VGS@713636|Nitrosomonadales	28216|Betaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
REGS1_k127_8833784_28	323848.Nmul_A2064	2.014e-20	98.0	COG2905@1|root,COG2905@2|Bacteria,1QXGK@1224|Proteobacteria,2WHHI@28216|Betaproteobacteria,3730N@32003|Nitrosomonadales	28216|Betaproteobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
REGS1_k127_8833784_16	1485544.JQKP01000014_gene1900	6.905e-126	406.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria,44UZN@713636|Nitrosomonadales	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
REGS1_k127_8833784_21	395494.Galf_1302	6.615e-95	316.0	COG0546@1|root,COG0546@2|Bacteria,1RCXJ@1224|Proteobacteria,2VS13@28216|Betaproteobacteria,44VR8@713636|Nitrosomonadales	28216|Betaproteobacteria	S	HAD-superfamily hydrolase, subfamily IA, variant 1	gph	-	3.1.3.105	ko:K22292	ko00520,map00520	-	R11785	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_8833784_30	580332.Slit_1184	1.06e-16	94.0	COG2200@1|root,COG3829@1|root,COG2200@2|Bacteria,COG3829@2|Bacteria,1NTHT@1224|Proteobacteria,2W1FA@28216|Betaproteobacteria,44WAB@713636|Nitrosomonadales	28216|Betaproteobacteria	KT	TIGRFAM PAS sensor protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PAS_4
REGS1_k127_8833784_14	580332.Slit_2071	8.522e-160	519.0	COG2114@1|root,COG2703@1|root,COG2114@2|Bacteria,COG2703@2|Bacteria,1MV1V@1224|Proteobacteria,2VJ72@28216|Betaproteobacteria,44WAE@713636|Nitrosomonadales	28216|Betaproteobacteria	PT	SMART adenylyl cyclase class-3 4 guanylyl cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,HAMP
REGS1_k127_8833784_15	395494.Galf_0043	1.249e-137	441.0	COG0708@1|root,COG0708@2|Bacteria,1MVII@1224|Proteobacteria,2VI74@28216|Betaproteobacteria,44V0I@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Endonuclease/Exonuclease/phosphatase family	exoA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
REGS1_k127_8833784_19	1485544.JQKP01000002_gene1506	9.963e-110	357.0	COG0461@1|root,COG0461@2|Bacteria,1MW6F@1224|Proteobacteria,2VH9U@28216|Betaproteobacteria,44VM2@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
REGS1_k127_8833784_29	1163617.SCD_n00093	4.248e-20	98.0	2DPC5@1|root,331GN@2|Bacteria,1NCRC@1224|Proteobacteria,2VVUT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Domain of unknown function (DUF4124)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4124
REGS1_k127_8833784_25	1485544.JQKP01000002_gene1561	3.865e-43	160.0	COG0288@1|root,COG0288@2|Bacteria,1NGFN@1224|Proteobacteria,2VR34@28216|Betaproteobacteria,44VSI@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Carbonic anhydrase	cynT	GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
REGS1_k127_8891429_20	580332.Slit_2816	2.337e-15	76.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,2VJ7R@28216|Betaproteobacteria,44W6T@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC-2 type transporter	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
REGS1_k127_8891429_13	580332.Slit_2817	5.469e-61	214.0	COG0824@1|root,COG0824@2|Bacteria,1RCSP@1224|Proteobacteria,2VXA8@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_2
REGS1_k127_8891429_3	1485544.JQKP01000002_gene1427	2.517e-151	484.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,2VI3G@28216|Betaproteobacteria,44VG9@713636|Nitrosomonadales	28216|Betaproteobacteria	V	PFAM ABC transporter related	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
REGS1_k127_8891429_11	395494.Galf_2736	1.489e-81	276.0	COG2945@1|root,COG2945@2|Bacteria,1MUDY@1224|Proteobacteria,2VJ8M@28216|Betaproteobacteria,44VV2@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4,Peptidase_S15
REGS1_k127_8891429_17	395494.Galf_2735	1.556e-53	191.0	COG3411@1|root,COG3411@2|Bacteria,1MZR4@1224|Proteobacteria,2VTY1@28216|Betaproteobacteria,44VZ4@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Ferredoxin	fdx	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
REGS1_k127_8891429_7	580332.Slit_2821	3.365e-115	381.0	COG5652@1|root,COG5652@2|Bacteria,1PJUW@1224|Proteobacteria,2VHEZ@28216|Betaproteobacteria,44V77@713636|Nitrosomonadales	28216|Betaproteobacteria	S	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
REGS1_k127_8891429_14	580332.Slit_2372	4.345e-60	211.0	COG2703@1|root,COG2703@2|Bacteria,1RI40@1224|Proteobacteria,2VVCK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Hemerythrin HHE cation binding domain protein	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
REGS1_k127_8891429_10	1485544.JQKP01000002_gene1579	2.545e-86	290.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VKD8@28216|Betaproteobacteria,44UZG@713636|Nitrosomonadales	28216|Betaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activ_2
REGS1_k127_8891429_1	1485544.JQKP01000002_gene1578	1.482e-274	861.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,2VIDI@28216|Betaproteobacteria,44UYE@713636|Nitrosomonadales	28216|Betaproteobacteria	T	histidine kinase HAMP region domain protein	ntrY	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_7,PAS_8
REGS1_k127_8891429_18	1485544.JQKP01000002_gene1577	2.365e-52	192.0	29CX4@1|root,2ZZV8@2|Bacteria,1RFY7@1224|Proteobacteria,2VR98@28216|Betaproteobacteria,44VWB@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Domain of unknown function (DUF4390)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4390
REGS1_k127_8891429_2	1485544.JQKP01000002_gene1576	1.326e-181	579.0	COG0144@1|root,COG0144@2|Bacteria,1MWPE@1224|Proteobacteria,2VI4V@28216|Betaproteobacteria,44VEQ@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
REGS1_k127_8891429_5	1485544.JQKP01000002_gene1575	6.649e-128	417.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,2VIS2@28216|Betaproteobacteria,44V35@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
REGS1_k127_8891429_12	395494.Galf_0022	2.917e-72	246.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,2VQ4N@28216|Betaproteobacteria,44VPM@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
REGS1_k127_8891429_9	580332.Slit_0007	1.913e-113	376.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,2VIZJ@28216|Betaproteobacteria,44VKI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
REGS1_k127_8891429_4	1485544.JQKP01000002_gene1572	2.07e-146	473.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,2VH3W@28216|Betaproteobacteria,44VI9@713636|Nitrosomonadales	28216|Betaproteobacteria	L	DNA recombination-mediator protein A	smf	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
REGS1_k127_8891429_16	580332.Slit_0005	7.131e-60	211.0	COG2922@1|root,COG2922@2|Bacteria,1RD5F@1224|Proteobacteria,2VRJF@28216|Betaproteobacteria,44VVY@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF494)	smg	-	-	ko:K03747	-	-	-	-	ko00000	-	-	-	DUF494
REGS1_k127_8891429_0	580332.Slit_0004	0.0	1379.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,1MUFZ@1224|Proteobacteria,2VHUF@28216|Betaproteobacteria,44UZ5@713636|Nitrosomonadales	28216|Betaproteobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt,zf-C4_Topoisom
REGS1_k127_8891429_19	580332.Slit_2373	9.327e-47	172.0	COG1959@1|root,COG1959@2|Bacteria,1N05H@1224|Proteobacteria,2VU41@28216|Betaproteobacteria,44WMB@713636|Nitrosomonadales	28216|Betaproteobacteria	K	TIGRFAM transcriptional regulator, Rrf2 family	nsrR	-	-	ko:K13771	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	Rrf2
REGS1_k127_8891429_15	580332.Slit_2374	4.466e-60	210.0	COG2346@1|root,COG2346@2|Bacteria	2|Bacteria	O	COG2346, Truncated hemoglobins	glbN	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057	-	ko:K03406,ko:K06886	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Bac_globin
REGS1_k127_8891429_6	580332.Slit_2375	6.077e-126	412.0	COG1018@1|root,COG1018@2|Bacteria,1REP4@1224|Proteobacteria,2WGRI@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Oxidoreductase FAD-binding domain	-	-	1.18.1.7	ko:K14581	ko00624,ko00626,ko00627,ko00633,ko00642,ko01100,ko01120,ko01220,map00624,map00626,map00627,map00633,map00642,map01100,map01120,map01220	M00534,M00638	R02968,R05422,R05423,R05424,R05425,R05426,R05427,R06909,R06930,R06937,R07704,R07706,R07709,R07710,R09159,R09233	RC00091,RC00098,RC00157,RC00274,RC00275,RC00490,RC01376,RC01377,RC01801	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
REGS1_k127_8891429_8	395494.Galf_0348	8.328e-115	376.0	COG2607@1|root,COG2607@2|Bacteria,1MVMX@1224|Proteobacteria,2VID5@28216|Betaproteobacteria,44W4V@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF815)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
REGS1_k127_8919246_20	1485544.JQKP01000002_gene1436	9.451e-130	416.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,2VJPX@28216|Betaproteobacteria,44VKQ@713636|Nitrosomonadales	28216|Betaproteobacteria	F	PFAM AICARFT IMPCHase bienzyme formylation region	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
REGS1_k127_8919246_28	580332.Slit_0292	1.234e-34	134.0	COG2901@1|root,COG2901@2|Bacteria,1N7MJ@1224|Proteobacteria,2VVQK@28216|Betaproteobacteria,44W2K@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Bacterial regulatory protein, Fis family	fis	-	-	ko:K03557	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000,ko03036,ko03400	-	-	-	HTH_8
REGS1_k127_8919246_9	580332.Slit_0291	3.47e-178	562.0	COG0042@1|root,COG0042@2|Bacteria,1MV5V@1224|Proteobacteria,2VHBP@28216|Betaproteobacteria,44UYZ@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dusB	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
REGS1_k127_8919246_12	1485544.JQKP01000002_gene1422	8.028e-172	546.0	COG0654@1|root,COG0654@2|Bacteria,1MU6I@1224|Proteobacteria,2VIPS@28216|Betaproteobacteria,44V5S@713636|Nitrosomonadales	28216|Betaproteobacteria	CH	TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family	ubiF	-	-	ko:K03185	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04989,R08773	RC02670	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,SE
REGS1_k127_8919246_23	1485544.JQKP01000002_gene1423	1.356e-81	280.0	COG1651@1|root,COG1651@2|Bacteria,1RD39@1224|Proteobacteria,2VIHV@28216|Betaproteobacteria,44VQC@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	dsbC	-	5.3.4.1	ko:K03981	-	-	-	-	ko00000,ko01000,ko02044,ko03110	3.A.7.11.1	-	-	DsbC_N,Thioredoxin_2
REGS1_k127_8919246_8	1485544.JQKP01000007_gene2017	5.475e-186	589.0	COG4536@1|root,COG4536@2|Bacteria,1NZ99@1224|Proteobacteria,2WGFR@28216|Betaproteobacteria,44V5P@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Domain of unknown function DUF21	corB	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
REGS1_k127_8919246_25	1123400.KB904813_gene3048	1.266e-56	201.0	COG0697@1|root,COG0697@2|Bacteria,1N2BC@1224|Proteobacteria,1SAEH@1236|Gammaproteobacteria	1236|Gammaproteobacteria	EG	Protein of unknown function (DUF2569)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2569
REGS1_k127_8919246_4	580332.Slit_2706	1.436e-209	657.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2VJ84@28216|Betaproteobacteria,44V2G@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
REGS1_k127_8919246_24	580332.Slit_2707	8.198e-70	240.0	COG0664@1|root,COG0664@2|Bacteria,1NBRS@1224|Proteobacteria,2WCFJ@28216|Betaproteobacteria,44VZA@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
REGS1_k127_8919246_0	1485544.JQKP01000002_gene1616	0.0	1482.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,2VHDH@28216|Betaproteobacteria,44V1H@713636|Nitrosomonadales	28216|Betaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
REGS1_k127_8919246_21	1288494.EBAPG3_28070	3.804e-91	309.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,2VKR8@28216|Betaproteobacteria,371UP@32003|Nitrosomonadales	28216|Betaproteobacteria	M	Peptidase family M23	-	-	3.4.24.75	ko:K08259	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
REGS1_k127_8919246_31	1163617.SCD_n02476	7.296e-17	86.0	COG4701@1|root,COG4701@2|Bacteria,1N8HR@1224|Proteobacteria,2VW5Y@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
REGS1_k127_8919246_33	1485544.JQKP01000002_gene1618	3.46e-09	61.0	2AG2M@1|root,3166Z@2|Bacteria,1PWZE@1224|Proteobacteria,2WCHD@28216|Betaproteobacteria,44W3K@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_8919246_14	580332.Slit_2712	6.627e-159	505.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2VHI8@28216|Betaproteobacteria,44V9K@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
REGS1_k127_8919246_11	580332.Slit_2713	5.93e-173	550.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,2VH0S@28216|Betaproteobacteria,44VGJ@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
REGS1_k127_8919246_3	580332.Slit_2714	1.918e-226	706.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,44UZY@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
REGS1_k127_8919246_27	1123392.AQWL01000002_gene1866	2.852e-43	166.0	COG1589@1|root,COG1589@2|Bacteria,1N0T7@1224|Proteobacteria,2VRMV@28216|Betaproteobacteria,1KRV6@119069|Hydrogenophilales	119069|Hydrogenophilales	M	POTRA domain, FtsQ-type	-	-	-	-	-	-	-	-	-	-	-	-	FtsQ,POTRA_1
REGS1_k127_8919246_15	1485544.JQKP01000002_gene1623	1.357e-157	502.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,2VHIW@28216|Betaproteobacteria,44V42@713636|Nitrosomonadales	28216|Betaproteobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
REGS1_k127_8919246_19	580332.Slit_2717	9.638e-144	461.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,2W9FB@28216|Betaproteobacteria,44WEF@713636|Nitrosomonadales	28216|Betaproteobacteria	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	-	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
REGS1_k127_8919246_2	1485544.JQKP01000002_gene1625	1.723e-248	774.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,2VIKZ@28216|Betaproteobacteria,44VEH@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Mur ligase family, catalytic domain	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_8919246_18	580332.Slit_2719	3.582e-144	465.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,2VH32@28216|Betaproteobacteria,44V43@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
REGS1_k127_8919246_13	580332.Slit_2720	1.904e-170	544.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,2VI5Q@28216|Betaproteobacteria,44UZV@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Peptidoglycan polymerase that is essential for cell division	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
REGS1_k127_8919246_7	1485544.JQKP01000002_gene1628	8.514e-192	608.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,2VHJ1@28216|Betaproteobacteria,44V6N@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
REGS1_k127_8919246_6	580332.Slit_2722	9.464e-200	626.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,2VHAP@28216|Betaproteobacteria,44V5Q@713636|Nitrosomonadales	28216|Betaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
REGS1_k127_8919246_10	395494.Galf_0330	7.414e-174	563.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,2VH2H@28216|Betaproteobacteria,44VA0@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10,6.3.2.13	ko:K01929,ko:K15792	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R02788,R04573,R04617	RC00064,RC00090,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_8919246_5	580332.Slit_2724	4.732e-209	660.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,2WGFS@28216|Betaproteobacteria,44VE4@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
REGS1_k127_8919246_1	580332.Slit_2725	3.396e-258	807.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,2VIZM@28216|Betaproteobacteria,44VFB@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Catalyzes cross-linking of the peptidoglycan cell wall at the division septum	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
REGS1_k127_8919246_29	580332.Slit_2726	3.56e-27	113.0	COG3116@1|root,COG3116@2|Bacteria,1N6WK@1224|Proteobacteria,2VW1W@28216|Betaproteobacteria,44W2Z@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic	ftsL	-	-	ko:K03586	-	-	-	-	ko00000,ko03036	-	-	-	FtsL
REGS1_k127_8919246_17	580332.Slit_2727	2.725e-144	463.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,2VIYT@28216|Betaproteobacteria,44VNN@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
REGS1_k127_8919246_22	580332.Slit_2728	1.703e-82	275.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,2VRGP@28216|Betaproteobacteria,44VXJ@713636|Nitrosomonadales	28216|Betaproteobacteria	K	MraZ protein, putative antitoxin-like	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
REGS1_k127_8919246_16	395494.Galf_2064	5.817e-148	478.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,2VJR5@28216|Betaproteobacteria,44V3R@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
REGS1_k127_8919246_26	1485544.JQKP01000013_gene1791	2.737e-48	175.0	COG1226@1|root,COG1226@2|Bacteria,1MU1R@1224|Proteobacteria,2WEJI@28216|Betaproteobacteria,44V2J@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Ion channel	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_N
REGS1_k127_8933049_3	1485544.JQKP01000015_gene2073	3.334e-122	403.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,2VH97@28216|Betaproteobacteria,44UZ4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
REGS1_k127_8933049_5	580332.Slit_1483	3.61e-49	178.0	COG0858@1|root,COG0858@2|Bacteria,1MZPE@1224|Proteobacteria,2VR43@28216|Betaproteobacteria,44VW4@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
REGS1_k127_8933049_0	580332.Slit_1482	0.0	1230.0	COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,2VK2H@28216|Betaproteobacteria,44V5A@713636|Nitrosomonadales	28216|Betaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N,IF2_assoc
REGS1_k127_8933049_1	580332.Slit_1481	8.253e-266	826.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,2VH2X@28216|Betaproteobacteria,44VCN@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
REGS1_k127_8933049_4	580332.Slit_1480	1.01e-62	221.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,2VSRT@28216|Betaproteobacteria,44VTX@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
REGS1_k127_8933049_2	1485544.JQKP01000019_gene21	1.645e-176	564.0	COG1070@1|root,COG2827@1|root,COG1070@2|Bacteria,COG2827@2|Bacteria,1MW4A@1224|Proteobacteria,2VI4Z@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
REGS1_k127_8973715_0	1122604.JONR01000009_gene2401	5.636e-214	677.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,1S076@1236|Gammaproteobacteria,1X9SG@135614|Xanthomonadales	135614|Xanthomonadales	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
REGS1_k127_8973715_2	580332.Slit_2729	2.206e-67	235.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,LCCL,OmpA
REGS1_k127_8973715_1	580332.Slit_1287	9.747e-128	410.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,2VHAR@28216|Betaproteobacteria,44V3T@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides	nagZ	-	2.7.8.7,3.2.1.52	ko:K00997,ko:K01207	ko00520,ko00531,ko00770,ko01100,ko01501,map00520,map00531,map00770,map01100,map01501	M00628	R00022,R01625,R05963,R07809,R07810,R10831	RC00002,RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
REGS1_k127_908036_4	1304883.KI912532_gene2041	1.313e-137	443.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,2VJCQ@28216|Betaproteobacteria,2KUHW@206389|Rhodocyclales	206389|Rhodocyclales	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
REGS1_k127_908036_13	713587.THITH_07500	6.967e-25	117.0	COG3043@1|root,COG3043@2|Bacteria	2|Bacteria	C	anaerobic respiration	napB	GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114	-	ko:K02568	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798	RC02812	ko00000,ko00001,ko00002	-	-	iAF1260.b2203,iBWG_1329.BWG_1976,iE2348C_1286.E2348C_2347,iECDH10B_1368.ECDH10B_2360,iECDH1ME8569_1439.ECDH1ME8569_2138,iECED1_1282.ECED1_2668,iECH74115_1262.ECH74115_3340,iECIAI39_1322.ECIAI39_2341,iECNA114_1301.ECNA114_2295,iECOK1_1307.ECOK1_2437,iECP_1309.ECP_2244,iECS88_1305.ECS88_2350,iECSF_1327.ECSF_2084,iECSP_1301.ECSP_3082,iECUMN_1333.ECUMN_2538,iETEC_1333.ETEC_2337,iEcDH1_1363.EcDH1_1456,iEcolC_1368.EcolC_1447,iG2583_1286.G2583_2744,iJO1366.b2203,iLF82_1304.LF82_1453,iNRG857_1313.NRG857_11180,iSFV_1184.SFV_2279,iSF_1195.SF2287,iSFxv_1172.SFxv_2521,iS_1188.S2417,iUMN146_1321.UM146_05790,iY75_1357.Y75_RS11525	NapB
REGS1_k127_908036_0	768671.ThimaDRAFT_4410	0.0	1360.0	COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria,1WW7D@135613|Chromatiales	135613|Chromatiales	C	Molybdopterin oxidoreductase Fe4S4 domain	napA	-	-	ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
REGS1_k127_908036_6	580332.Slit_1477	2.213e-99	325.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,2VI7G@28216|Betaproteobacteria,44VQ2@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
REGS1_k127_908036_7	580332.Slit_1476	1.969e-95	316.0	COG0235@1|root,COG0235@2|Bacteria,1MW7B@1224|Proteobacteria,2VQBC@28216|Betaproteobacteria,44VVE@713636|Nitrosomonadales	28216|Betaproteobacteria	G	PFAM class II aldolase adducin family protein	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
REGS1_k127_908036_3	580332.Slit_1475	5.817e-160	507.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,2VJQQ@28216|Betaproteobacteria,44V13@713636|Nitrosomonadales	28216|Betaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	-	2.4.2.28	ko:K00772,ko:K03815	ko00230,ko00270,ko01100,ko01110,map00230,map00270,map01100,map01110	M00034	R01402,R02297	RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
REGS1_k127_908036_8	296591.Bpro_3095	8.843e-95	320.0	COG1295@1|root,COG1295@2|Bacteria,1NH82@1224|Proteobacteria,2VJW7@28216|Betaproteobacteria,4AAJH@80864|Comamonadaceae	28216|Betaproteobacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
REGS1_k127_908036_9	1313421.JHBV01000016_gene5425	8.061e-48	182.0	COG3000@1|root,COG3000@2|Bacteria,4NKP5@976|Bacteroidetes,1ISJC@117747|Sphingobacteriia	976|Bacteroidetes	I	Fatty acid hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	FA_hydroxylase
REGS1_k127_908036_12	580332.Slit_1238	3.059e-31	127.0	2CIC4@1|root,3328Z@2|Bacteria,1N7FS@1224|Proteobacteria,2VX81@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_908036_1	580332.Slit_1235	5.791e-239	747.0	COG2195@1|root,COG2195@2|Bacteria,1MUWK@1224|Proteobacteria,2VHR4@28216|Betaproteobacteria,44UZB@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Peptidase dimerisation domain	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
REGS1_k127_908036_5	243231.GSU0474	2.174e-124	418.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WIK8@28221|Deltaproteobacteria,43TNR@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_2,GGDEF,PAS,PAS_3,PAS_9,Response_reg
REGS1_k127_908036_11	1232410.KI421415_gene2960	6.404e-43	166.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions,2WP03@28221|Deltaproteobacteria,43SHH@69541|Desulfuromonadales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
REGS1_k127_908036_14	1005048.CFU_2547	2.168e-05	56.0	2AG7M@1|root,316CQ@2|Bacteria,1PXBX@1224|Proteobacteria,2W4C3@28216|Betaproteobacteria,4786R@75682|Oxalobacteraceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_908036_10	1122604.JONR01000014_gene218	4.236e-45	172.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,1S8HN@1236|Gammaproteobacteria,1X62E@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
REGS1_k127_908036_2	1366050.N234_05160	2.562e-203	649.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,2VMGB@28216|Betaproteobacteria,1KCQD@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
REGS1_k127_9089456_2	580332.Slit_2408	2.543e-149	485.0	COG0795@1|root,COG0795@2|Bacteria,1MVW3@1224|Proteobacteria,2VHA1@28216|Betaproteobacteria,44UYI@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptG	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
REGS1_k127_9089456_1	580332.Slit_2409	9.981e-158	505.0	COG0795@1|root,COG0795@2|Bacteria,1MUF2@1224|Proteobacteria,2VH9C@28216|Betaproteobacteria,44V0Y@713636|Nitrosomonadales	28216|Betaproteobacteria	S	PFAM permease YjgP YjgQ family protein	lptF	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
REGS1_k127_9089456_0	580332.Slit_2410	4.368e-238	744.0	COG0260@1|root,COG0260@2|Bacteria,1MUF9@1224|Proteobacteria,2VH79@28216|Betaproteobacteria,44V6F@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
REGS1_k127_9096434_1	1123072.AUDH01000008_gene275	1.036e-62	236.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2TR0J@28211|Alphaproteobacteria,2JP9V@204441|Rhodospirillales	204441|Rhodospirillales	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
REGS1_k127_9096434_2	56780.SYN_01342	5.894e-52	194.0	COG1173@1|root,COG1173@2|Bacteria,1MU26@1224|Proteobacteria,42MFP@68525|delta/epsilon subdivisions,2WJ47@28221|Deltaproteobacteria,2MQ6J@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
REGS1_k127_9096434_3	1051501.AYTL01000027_gene687	2.017e-50	191.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus	91061|Bacilli	P	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components	appB	GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
REGS1_k127_9096434_0	1125863.JAFN01000001_gene2822	3.42e-123	414.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	extracellular solute-binding protein, family 5	-	-	-	ko:K02035,ko:K15584	ko02010,ko02024,map02010,map02024	M00239,M00440	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
REGS1_k127_9108333_1	580332.Slit_2430	7.326e-23	100.0	COG2900@1|root,COG2900@2|Bacteria,1NGFM@1224|Proteobacteria,2VXFA@28216|Betaproteobacteria,44W38@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SlyX	-	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
REGS1_k127_9108333_2	1038862.KB893917_gene4439	4.513e-21	104.0	2A7SG@1|root,30WRD@2|Bacteria,1RENW@1224|Proteobacteria,2U8QE@28211|Alphaproteobacteria,3JYSN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9108333_0	1095769.CAHF01000022_gene195	6.395e-76	273.0	COG0501@1|root,COG0501@2|Bacteria,1NA37@1224|Proteobacteria,2VIMA@28216|Betaproteobacteria	28216|Betaproteobacteria	O	PFAM peptidase M48 Ste24p	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
REGS1_k127_9119122_3	626418.bglu_2g16070	1.602e-10	61.0	COG3547@1|root,COG3547@2|Bacteria,1MXKJ@1224|Proteobacteria,2VP05@28216|Betaproteobacteria,1K8AN@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Transposase IS116 IS110 IS902 family protein	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
REGS1_k127_9119122_4	487316.BBNM01000004_gene638	2.821e-08	61.0	29KS6@1|root,307PK@2|Bacteria,1QS3J@1224|Proteobacteria,1RVEP@1236|Gammaproteobacteria,3NP1B@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9119122_2	666681.M301_1496	1.809e-98	331.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2VMGT@28216|Betaproteobacteria,2KKT2@206350|Nitrosomonadales	206350|Nitrosomonadales	GK	PFAM ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
REGS1_k127_9119122_0	582744.Msip34_1273	4.204e-276	863.0	COG1449@1|root,COG1449@2|Bacteria,1Q9WP@1224|Proteobacteria,2VN9S@28216|Betaproteobacteria,2KNF1@206350|Nitrosomonadales	206350|Nitrosomonadales	G	Domain of unknown function (DUF1926)	-	-	2.4.1.25	ko:K22451	ko00500,map00500	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH57	-	DUF1925,DUF1926,Glyco_hydro_57
REGS1_k127_9119122_1	1163617.SCD_n01924	2.607e-147	474.0	COG1449@1|root,COG1449@2|Bacteria,1P2YJ@1224|Proteobacteria,2VHA4@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
REGS1_k127_912320_10	1485544.JQKP01000004_gene528	2.545e-05	50.0	COG3659@1|root,COG3659@2|Bacteria,1Q8C7@1224|Proteobacteria,2VJFC@28216|Betaproteobacteria,44W6W@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Carbohydrate-selective porin, OprB family	oprB	-	-	-	-	-	-	-	-	-	-	-	OprB
REGS1_k127_912320_1	580332.Slit_0675	4.099e-249	775.0	COG0215@1|root,COG0215@2|Bacteria,1MV8H@1224|Proteobacteria,2VHN4@28216|Betaproteobacteria,44VP0@713636|Nitrosomonadales	28216|Betaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
REGS1_k127_912320_0	580332.Slit_0673	0.0	1034.0	COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,2VHZX@28216|Betaproteobacteria,44V1S@713636|Nitrosomonadales	28216|Betaproteobacteria	J	PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
REGS1_k127_912320_7	1485544.JQKP01000001_gene885	3.067e-56	202.0	COG0457@1|root,COG0457@2|Bacteria,1Q84V@1224|Proteobacteria,2VJAQ@28216|Betaproteobacteria,44V9I@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,TPR_11,TPR_16,TPR_17,TPR_19,TPR_8
REGS1_k127_912320_6	1485544.JQKP01000001_gene883	3.37e-73	253.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2VQ3Z@28216|Betaproteobacteria,44VQD@713636|Nitrosomonadales	28216|Betaproteobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
REGS1_k127_912320_4	1485544.JQKP01000001_gene882	5.954e-99	328.0	COG2908@1|root,COG2908@2|Bacteria,1N3U7@1224|Proteobacteria,2VQRP@28216|Betaproteobacteria,44VBW@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxH	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
REGS1_k127_912320_2	472759.Nhal_1079	7.28e-146	469.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria	1224|Proteobacteria	Q	Multi-copper	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
REGS1_k127_912320_5	472759.Nhal_1080	2.603e-74	256.0	COG2010@1|root,COG3474@1|root,COG2010@2|Bacteria,COG3474@2|Bacteria,1R7BC@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome C, class I	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C
REGS1_k127_912320_9	472759.Nhal_1081	2.215e-36	142.0	COG2010@1|root,COG2010@2|Bacteria,1PDUJ@1224|Proteobacteria,1SUEN@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
REGS1_k127_912320_3	472759.Nhal_1082	6.471e-113	373.0	COG2132@1|root,COG2132@2|Bacteria,1MV74@1224|Proteobacteria,1RXZF@1236|Gammaproteobacteria,1X1G6@135613|Chromatiales	135613|Chromatiales	CQ	Copper binding proteins, plastocyanin/azurin family	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_3
REGS1_k127_912320_8	1123392.AQWL01000001_gene1655	1.602e-37	148.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,2W1AG@28216|Betaproteobacteria,1KS01@119069|Hydrogenophilales	119069|Hydrogenophilales	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
REGS1_k127_9168890_13	640081.Dsui_1140	1.994e-67	233.0	COG0477@1|root,COG2814@2|Bacteria,1NE49@1224|Proteobacteria,2VNGV@28216|Betaproteobacteria,2KVR8@206389|Rhodocyclales	206389|Rhodocyclales	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
REGS1_k127_9168890_10	640081.Dsui_1139	5.241e-80	268.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2VQ0S@28216|Betaproteobacteria,2KYFQ@206389|Rhodocyclales	206389|Rhodocyclales	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
REGS1_k127_9168890_17	395494.Galf_2727	1.986e-43	164.0	COG3350@1|root,COG3350@2|Bacteria,1NBVM@1224|Proteobacteria,2WDC1@28216|Betaproteobacteria,44WNM@713636|Nitrosomonadales	28216|Betaproteobacteria	S	monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9168890_8	1429916.X566_00390	1.165e-104	343.0	COG2020@1|root,COG2020@2|Bacteria,1MUBZ@1224|Proteobacteria,2TQZQ@28211|Alphaproteobacteria,3JR2M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
REGS1_k127_9168890_20	1132855.KB913035_gene1506	6.516e-30	120.0	2DVDD@1|root,32UZ7@2|Bacteria,1NGRW@1224|Proteobacteria,2VY85@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF2933)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2933
REGS1_k127_9168890_1	395494.Galf_2724	0.0	1229.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,44VKX@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
REGS1_k127_9168890_24	697282.Mettu_3437	2.489e-07	58.0	29FX1@1|root,34453@2|Bacteria,1P3CX@1224|Proteobacteria,1SVJS@1236|Gammaproteobacteria,1XGJE@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9168890_22	472759.Nhal_1698	5.491e-11	68.0	29FX1@1|root,34453@2|Bacteria,1P3CX@1224|Proteobacteria,1SVJS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
REGS1_k127_9168890_0	232721.Ajs_2703	0.0	1629.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,4A9J4@80864|Comamonadaceae	28216|Betaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
REGS1_k127_9168890_4	580332.Slit_1864	1.467e-176	563.0	COG0845@1|root,COG5569@1|root,COG0845@2|Bacteria,COG5569@2|Bacteria,1MVAS@1224|Proteobacteria,2VJXV@28216|Betaproteobacteria,44VFA@713636|Nitrosomonadales	28216|Betaproteobacteria	M	TIGRFAM efflux transporter, RND family, MFP subunit	cusB	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	CusF_Ec,HlyD_D23
REGS1_k127_9168890_3	580332.Slit_1863	1.715e-193	612.0	COG1538@1|root,COG1538@2|Bacteria,1PCPQ@1224|Proteobacteria,2VMAB@28216|Betaproteobacteria,44VGB@713636|Nitrosomonadales	28216|Betaproteobacteria	MU	PFAM outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
REGS1_k127_9168890_19	580332.Slit_1862	1.188e-30	126.0	2BUWG@1|root,32Q8K@2|Bacteria,1PJWU@1224|Proteobacteria,2W88K@28216|Betaproteobacteria,44WJH@713636|Nitrosomonadales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2946
REGS1_k127_9168890_2	1540221.JQNI01000004_gene165	1.096e-200	632.0	28HKD@1|root,2Z7V8@2|Bacteria,1WMD0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	type ii restriction enzyme	-	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
REGS1_k127_9168890_23	1288826.MSNKSG1_02419	1.409e-10	72.0	COG2963@1|root,COG2963@2|Bacteria	2|Bacteria	L	transposase activity	-	-	-	ko:K07483,ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1,TniQ,TnsD
REGS1_k127_9168890_6	580332.Slit_0649	1.169e-128	416.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,2VI91@28216|Betaproteobacteria,44VB2@713636|Nitrosomonadales	28216|Betaproteobacteria	K	Sigma-70 factor, region 1.2	rpoH	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
REGS1_k127_9168890_18	391615.ABSJ01000054_gene1466	9.111e-35	143.0	2EUFJ@1|root,33MXU@2|Bacteria,1NZHB@1224|Proteobacteria,1SQC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
REGS1_k127_9168890_11	1202962.KB907170_gene2407	1.444e-75	258.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,1S4SE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Peptidoglycan-synthase activator LpoB	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
REGS1_k127_9168890_9	653733.Selin_0436	5.754e-92	319.0	COG3014@1|root,COG3014@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
REGS1_k127_9168890_16	349124.Hhal_1830	1.139e-45	178.0	COG0136@1|root,335ZB@2|Bacteria,1NQEQ@1224|Proteobacteria,1SI1Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	LPP20 lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	LPP20
REGS1_k127_9168890_5	580332.Slit_2467	5.784e-174	554.0	COG0438@1|root,COG0438@2|Bacteria,1MUB7@1224|Proteobacteria,2W931@28216|Betaproteobacteria,44WM2@713636|Nitrosomonadales	28216|Betaproteobacteria	H	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
REGS1_k127_9168890_12	580332.Slit_2468	1.383e-68	238.0	COG0671@1|root,COG0671@2|Bacteria,1RJ1T@1224|Proteobacteria,2VTYD@28216|Betaproteobacteria	28216|Betaproteobacteria	I	PFAM phosphoesterase, PA-phosphatase related	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
REGS1_k127_9168890_14	580332.Slit_2464	3.11e-58	215.0	COG0204@1|root,COG0204@2|Bacteria,1N2DG@1224|Proteobacteria,2VSJD@28216|Betaproteobacteria,44W16@713636|Nitrosomonadales	28216|Betaproteobacteria	I	Phosphate acyltransferases	plsC	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
REGS1_k127_9168890_7	580332.Slit_2465	6.344e-109	358.0	COG3176@1|root,COG3176@2|Bacteria,1MWIM@1224|Proteobacteria,2VH4B@28216|Betaproteobacteria,44WCP@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5
REGS1_k127_9168890_15	580332.Slit_2466	1.528e-52	187.0	COG0818@1|root,COG0818@2|Bacteria,1MZ3Q@1224|Proteobacteria,2VU5Y@28216|Betaproteobacteria,44WG1@713636|Nitrosomonadales	28216|Betaproteobacteria	M	Recycling of diacylglycerol produced during the turnover of membrane phospholipid	-	-	2.7.1.107	ko:K00901	ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
REGS1_k127_9181776_4	580332.Slit_0526	4.42e-30	119.0	COG0045@1|root,COG0045@2|Bacteria,1MVCE@1224|Proteobacteria,2VHBG@28216|Betaproteobacteria,44UZH@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
REGS1_k127_9181776_5	580332.Slit_1865	1.3e-07	53.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VHCZ@28216|Betaproteobacteria,44VI6@713636|Nitrosomonadales	28216|Betaproteobacteria	P	TIGRFAM heavy metal efflux pump, CzcA family	cusA	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
REGS1_k127_9181776_0	580332.Slit_0527	2.164e-175	551.0	COG0074@1|root,COG0074@2|Bacteria,1MUGA@1224|Proteobacteria,2VH1U@28216|Betaproteobacteria,44V0Q@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
REGS1_k127_9181776_2	580332.Slit_0528	3.411e-103	340.0	COG0861@1|root,COG0861@2|Bacteria,1MXSK@1224|Proteobacteria,2VHZ5@28216|Betaproteobacteria,44VMY@713636|Nitrosomonadales	28216|Betaproteobacteria	P	Integral membrane protein TerC family	-	-	-	-	-	-	-	-	-	-	-	-	TerC
REGS1_k127_9181776_3	580332.Slit_1433	5.413e-103	342.0	28P0I@1|root,2ZBX5@2|Bacteria,1RB8U@1224|Proteobacteria,2VQ6K@28216|Betaproteobacteria,44UZS@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function (DUF3025)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3025
REGS1_k127_9181776_1	1485544.JQKP01000001_gene1253	4.643e-152	482.0	COG0426@1|root,COG0426@2|Bacteria,1N2Y0@1224|Proteobacteria,2VH72@28216|Betaproteobacteria,44WBY@713636|Nitrosomonadales	28216|Betaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
REGS1_k127_987141_20	1144932.ATTF01000021_gene23	1.284e-12	71.0	COG5036@1|root,COG5036@2|Bacteria,1RG06@1224|Proteobacteria	1224|Proteobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
REGS1_k127_987141_18	1144932.ATTF01000017_gene1171	5.558e-51	189.0	COG1285@1|root,COG1285@2|Bacteria,1PD3I@1224|Proteobacteria,2UKD1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
REGS1_k127_987141_21	272562.CA_C3469	4.065e-05	56.0	COG2730@1|root,COG2730@2|Bacteria,1UYCF@1239|Firmicutes,24989@186801|Clostridia,36HIZ@31979|Clostridiaceae	186801|Clostridia	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
REGS1_k127_987141_2	1165096.ARWF01000001_gene1525	2.325e-224	704.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,2VHPW@28216|Betaproteobacteria,2KM71@206350|Nitrosomonadales	206350|Nitrosomonadales	P	TIGRFAM chromate transporter, chromate ion transporter (CHR) family	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
REGS1_k127_987141_16	580332.Slit_0149	1.045e-58	209.0	COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,44WH5@713636|Nitrosomonadales	28216|Betaproteobacteria	S	SMART CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
REGS1_k127_987141_12	395494.Galf_2685	4.948e-86	290.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,44WEU@713636|Nitrosomonadales	28216|Betaproteobacteria	L	TIGRFAM DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
REGS1_k127_987141_5	580332.Slit_0148	5.858e-139	445.0	COG0253@1|root,COG0253@2|Bacteria,1MWDH@1224|Proteobacteria,2VI0C@28216|Betaproteobacteria,44V70@713636|Nitrosomonadales	28216|Betaproteobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
REGS1_k127_987141_14	580332.Slit_0147	2.39e-77	264.0	COG3159@1|root,COG3159@2|Bacteria,1R4BP@1224|Proteobacteria,2VPN6@28216|Betaproteobacteria,44VRV@713636|Nitrosomonadales	28216|Betaproteobacteria	S	Protein of unknown function, DUF484	-	-	-	ko:K09921	-	-	-	-	ko00000	-	-	-	DUF484
REGS1_k127_987141_3	580332.Slit_0146	3.746e-150	479.0	COG4973@1|root,COG4973@2|Bacteria,1MUJJ@1224|Proteobacteria,2VJ5V@28216|Betaproteobacteria,44VAD@713636|Nitrosomonadales	28216|Betaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
REGS1_k127_987141_11	580332.Slit_0274	2.844e-98	338.0	COG0451@1|root,COG0451@2|Bacteria,1MWVJ@1224|Proteobacteria,2VJ3T@28216|Betaproteobacteria,44V5F@713636|Nitrosomonadales	28216|Betaproteobacteria	GM	NAD(P)H-binding	yeeZ	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10,RmlD_sub_bind,TrkA_N
REGS1_k127_987141_4	1163617.SCD_n02069	1.103e-146	478.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,2VKNG@28216|Betaproteobacteria	28216|Betaproteobacteria	J	SMART PUA domain containing protein	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
REGS1_k127_987141_13	983917.RGE_16370	2.528e-85	291.0	COG3344@1|root,COG3344@2|Bacteria,1RIDA@1224|Proteobacteria,2VRQF@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
REGS1_k127_987141_22	641112.ACOK01000098_gene273	0.0002844	47.0	COG1396@1|root,COG1396@2|Bacteria,1VG9X@1239|Firmicutes,25889@186801|Clostridia,3WM6C@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
REGS1_k127_987141_0	395494.Galf_0306	7.2e-287	893.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,2VHSK@28216|Betaproteobacteria,44W7H@713636|Nitrosomonadales	28216|Betaproteobacteria	H	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
REGS1_k127_987141_7	1132855.KB913035_gene395	1.282e-132	430.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2VH7F@28216|Betaproteobacteria,2KKHQ@206350|Nitrosomonadales	206350|Nitrosomonadales	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R01073	RC00440	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
REGS1_k127_987141_10	580332.Slit_0277	2.291e-108	353.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2VHGQ@28216|Betaproteobacteria,44VBD@713636|Nitrosomonadales	28216|Betaproteobacteria	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
REGS1_k127_987141_19	756272.Plabr_4336	4.667e-42	161.0	COG0614@1|root,COG0614@2|Bacteria,2J06G@203682|Planctomycetes	203682|Planctomycetes	P	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_3
REGS1_k127_987141_1	580332.Slit_0278	1.259e-272	843.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,2VI2V@28216|Betaproteobacteria,44V45@713636|Nitrosomonadales	28216|Betaproteobacteria	H	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
REGS1_k127_987141_8	580332.Slit_0279	3.291e-128	411.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,2VIZ6@28216|Betaproteobacteria,44V8F@713636|Nitrosomonadales	28216|Betaproteobacteria	G	HAD-hyrolase-like	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
REGS1_k127_987141_6	1485544.JQKP01000001_gene960	8.263e-134	428.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,2VIGU@28216|Betaproteobacteria,44V7D@713636|Nitrosomonadales	28216|Betaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
REGS1_k127_987141_17	580332.Slit_0283	9.92e-52	186.0	COG2967@1|root,COG2967@2|Bacteria,1MZ2Z@1224|Proteobacteria,2VSPE@28216|Betaproteobacteria,44VWC@713636|Nitrosomonadales	28216|Betaproteobacteria	P	ApaG domain	apaG	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
REGS1_k127_987141_15	1485544.JQKP01000001_gene962	6.958e-74	253.0	COG0500@1|root,COG2226@2|Bacteria,1MVIS@1224|Proteobacteria,2VSGQ@28216|Betaproteobacteria,44VSW@713636|Nitrosomonadales	28216|Betaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
REGS1_k127_987141_9	580332.Slit_0284	2.072e-123	402.0	COG2821@1|root,COG2821@2|Bacteria,1MXD4@1224|Proteobacteria,2VHBF@28216|Betaproteobacteria,44VPE@713636|Nitrosomonadales	28216|Betaproteobacteria	M	MltA specific insert domain	mltA	-	-	ko:K08304	-	-	-	-	ko00000,ko01000,ko01011	-	GH102	-	3D,MltA
## 2339 queries scanned
## Total time (seconds): 35.05819010734558
## Rate: 66.72 q/s