## Tue Nov 12 07:36:22 2024
## emapper-2.1.12
## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/4635/S/SHD3_bin.13.fa -m mmseqs --itype genome -o SHD3_bin.13 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/bins_4635/SHD3_bin.13 --cpu 28
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
SHD3_k127_1002758_0	1220534.B655_1034	2.51e-70	260.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_1002758_2	1192034.CAP_8910	2.366e-28	127.0	COG0457@1|root,COG0457@2|Bacteria,1PC8F@1224|Proteobacteria,438AR@68525|delta/epsilon subdivisions,2X3K3@28221|Deltaproteobacteria,2YWDI@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SHD3_k127_1002758_1	404589.Anae109_1790	2.061e-33	130.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,42Y0E@68525|delta/epsilon subdivisions,2WT2T@28221|Deltaproteobacteria,2YVTQ@29|Myxococcales	28221|Deltaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	-	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SHD3_k127_1002758_3	1254432.SCE1572_09260	4.478e-24	117.0	COG1520@1|root,COG1520@2|Bacteria,1Q2JS@1224|Proteobacteria,4386K@68525|delta/epsilon subdivisions,2X3GH@28221|Deltaproteobacteria,2YVZV@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SHD3_k127_1004730_7	1254432.SCE1572_26235	5.513e-82	289.0	COG1559@1|root,COG1559@2|Bacteria,1MUQF@1224|Proteobacteria,42MPA@68525|delta/epsilon subdivisions,2WJ0Q@28221|Deltaproteobacteria,2YVDN@29|Myxococcales	28221|Deltaproteobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
SHD3_k127_1004730_12	1254432.SCE1572_27680	4.911e-43	161.0	COG0816@1|root,COG0816@2|Bacteria,1RDHZ@1224|Proteobacteria,42UC6@68525|delta/epsilon subdivisions,2WPDD@28221|Deltaproteobacteria,2YVEN@29|Myxococcales	28221|Deltaproteobacteria	J	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
SHD3_k127_1004730_3	448385.sce4545	3.858e-159	512.0	COG0124@1|root,COG0124@2|Bacteria,1MV2K@1224|Proteobacteria,42MG0@68525|delta/epsilon subdivisions,2WJE1@28221|Deltaproteobacteria,2YTVY@29|Myxococcales	28221|Deltaproteobacteria	J	histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
SHD3_k127_1004730_11	1192034.CAP_2402	2.589e-47	180.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_1004730_10	448385.sce4694	1.108e-51	195.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_1004730_9	1121920.AUAU01000022_gene2498	5.681e-64	228.0	COG2518@1|root,COG2518@2|Bacteria,3Y5EB@57723|Acidobacteria	57723|Acidobacteria	O	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	PCMT
SHD3_k127_1004730_2	1254432.SCE1572_17855	8.322e-163	536.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SHD3_k127_1004730_14	1192034.CAP_4827	4.264e-12	76.0	COG1520@1|root,COG3055@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Kelch_1,Laminin_G_3,Malectin,PQQ_2
SHD3_k127_1004730_5	1192034.CAP_3983	4.68e-114	385.0	COG2720@1|root,COG2720@2|Bacteria,1NG7U@1224|Proteobacteria,4319R@68525|delta/epsilon subdivisions,2WW7C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM VanW family protein	-	-	-	ko:K18346	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	PG_binding_4,VanW
SHD3_k127_1004730_13	1254432.SCE1572_32350	4.082e-19	88.0	COG2104@1|root,COG2104@2|Bacteria,1NG8E@1224|Proteobacteria,42WUA@68525|delta/epsilon subdivisions,2X2JA@28221|Deltaproteobacteria,2YW1J@29|Myxococcales	28221|Deltaproteobacteria	H	Thiamine biosynthesis	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
SHD3_k127_1004730_4	1254432.SCE1572_32360	4.545e-152	494.0	COG0621@1|root,COG0621@2|Bacteria,1MURS@1224|Proteobacteria,42MQ3@68525|delta/epsilon subdivisions,2WJEE@28221|Deltaproteobacteria,2YUPE@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
SHD3_k127_1004730_0	1192034.CAP_3998	6.536e-191	612.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42Z0F@68525|delta/epsilon subdivisions,2WTWA@28221|Deltaproteobacteria,2YUMY@29|Myxococcales	28221|Deltaproteobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
SHD3_k127_1004730_8	448385.sce3783	1.78e-76	269.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_1004730_6	1192034.CAP_8039	4.017e-91	321.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,CBM_2,Glyco_hydro_48
SHD3_k127_1010480_12	502025.Hoch_5610	6.938e-42	168.0	COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,43BQ1@68525|delta/epsilon subdivisions,2X718@28221|Deltaproteobacteria,2Z3MK@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
SHD3_k127_1010480_7	404589.Anae109_0319	3.954e-76	269.0	COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,42QF3@68525|delta/epsilon subdivisions,2WKPQ@28221|Deltaproteobacteria,2YYXT@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885,ko:K01894	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SHD3_k127_1010480_13	391625.PPSIR1_35012	2.161e-38	147.0	COG1403@1|root,COG1403@2|Bacteria,1P9ZG@1224|Proteobacteria,43835@68525|delta/epsilon subdivisions,2X9VY@28221|Deltaproteobacteria,2YVHD@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH,HNH_5
SHD3_k127_1010480_8	10224.XP_006813938.1	6.084e-69	246.0	COG1028@1|root,KOG1208@2759|Eukaryota,38CZD@33154|Opisthokonta,3BACQ@33208|Metazoa,3CSEJ@33213|Bilateria	33208|Metazoa	Q	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	1.1.1.300	ko:K11153,ko:K11161	ko00830,ko01100,map00830,map01100	-	R08379,R08383	RC00649	ko00000,ko00001,ko01000	-	-	-	adh_short
SHD3_k127_1010480_11	926560.KE387027_gene284	2.39e-44	166.0	COG0622@1|root,COG0622@2|Bacteria,1WMMY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	TIGRFAM phosphoesterase, MJ0936 family	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SHD3_k127_1010480_10	1123371.ATXH01000003_gene1959	3.345e-49	192.0	COG2265@1|root,COG2265@2|Bacteria,2GGUG@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SHD3_k127_1010480_15	1123508.JH636442_gene3945	1.337e-14	79.0	2FKEU@1|root,34C26@2|Bacteria,2J3XA@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1010480_1	502025.Hoch_6589	5.215e-226	714.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SHD3_k127_1010480_16	1408419.JHYG01000007_gene3078	7.272e-06	54.0	2EQUD@1|root,33IE5@2|Bacteria,1NN93@1224|Proteobacteria	2|Bacteria	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
SHD3_k127_1010480_5	1121456.ATVA01000011_gene1678	2.734e-91	308.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,42Q4Z@68525|delta/epsilon subdivisions,2WM28@28221|Deltaproteobacteria,2M9SQ@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM Glycoside hydrolase family 65, central catalytic	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2,Hydrolase
SHD3_k127_1010480_9	391625.PPSIR1_34178	1.445e-62	223.0	COG1234@1|root,COG1234@2|Bacteria,1PE64@1224|Proteobacteria,42RZR@68525|delta/epsilon subdivisions,2WNPZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SHD3_k127_1010480_14	670307.HYPDE_30998	7.612e-37	143.0	COG2164@1|root,COG2164@2|Bacteria,1N81P@1224|Proteobacteria,2UF42@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Cyclophilin-like	-	-	-	ko:K09143	-	-	-	-	ko00000	-	-	-	Cyclophil_like
SHD3_k127_1010480_0	56780.SYN_00075	7.856e-236	752.0	COG0031@1|root,COG0215@1|root,COG0031@2|Bacteria,COG0215@2|Bacteria,1MUBE@1224|Proteobacteria,42M6M@68525|delta/epsilon subdivisions,2WIQM@28221|Deltaproteobacteria,2MR3Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Pyridoxal-phosphate dependent enzyme	cysM	-	2.5.1.47,6.1.1.16	ko:K01738,ko:K01883,ko:K12339	ko00270,ko00920,ko00970,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map00970,map01100,map01110,map01120,map01130,map01200,map01230	M00021,M00359,M00360	R00897,R03132,R03601,R03650,R04859	RC00020,RC00055,RC00523,RC02814,RC02821,RC02876	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,PALP,tRNA-synt_1e
SHD3_k127_1010480_3	290397.Adeh_3183	1.025e-139	473.0	2DPRW@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,3334N@2|Bacteria,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
SHD3_k127_1010480_4	1125863.JAFN01000001_gene1081	1.598e-124	422.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42NRK@68525|delta/epsilon subdivisions,2WIM6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD	recD	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,UvrD_C_2
SHD3_k127_1010480_2	395493.BegalDRAFT_0662	1.371e-210	699.0	COG1074@1|root,COG1074@2|Bacteria,1MUTF@1224|Proteobacteria,1RPC6@1236|Gammaproteobacteria,45ZUQ@72273|Thiotrichales	72273|Thiotrichales	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	recB	-	3.1.11.5	ko:K03582	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
SHD3_k127_1010480_6	316067.Geob_1390	6.591e-82	291.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,42N6G@68525|delta/epsilon subdivisions,2WJ4Q@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
SHD3_k127_1011817_1	348824.LPU83_1849	1.269e-15	82.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574,ko:K12944	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	HAD_2,NUDIX
SHD3_k127_1011817_0	1242864.D187_009164	2.942e-33	140.0	COG4305@1|root,COG4305@2|Bacteria,1MYW4@1224|Proteobacteria	1224|Proteobacteria	G	Lytic transglycolase	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	CBM_2,Cellulase,DPBB_1,Pollen_allerg_1
SHD3_k127_1012222_0	1121403.AUCV01000057_gene3054	1.423e-93	319.0	COG5297@1|root,COG5297@2|Bacteria,1NDMY@1224|Proteobacteria,4333K@68525|delta/epsilon subdivisions,2WXH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,CelD_N,Glyco_hydro_9
SHD3_k127_1012222_3	448385.sce3556	1.468e-20	106.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_1012222_1	886293.Sinac_5728	1.764e-44	173.0	COG2264@1|root,COG2264@2|Bacteria,2J3H0@203682|Planctomycetes	203682|Planctomycetes	J	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SHD3_k127_1012222_2	1254432.SCE1572_50990	2.749e-24	111.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,CelD_N,Glyco_hydro_11,Glyco_hydro_9,HemolysinCabind,Lipase_GDSL_2,Polysacc_deac_1,SASA
SHD3_k127_1012440_2	1254432.SCE1572_43810	6.044e-41	161.0	COG0745@1|root,COG0745@2|Bacteria,1RI9T@1224|Proteobacteria,439X8@68525|delta/epsilon subdivisions,2WY8Z@28221|Deltaproteobacteria,2Z0MM@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
SHD3_k127_1012440_0	448385.sce1088	1.525e-188	604.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2YUSA@29|Myxococcales	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SHD3_k127_1012440_1	1254432.SCE1572_07800	1.11e-63	225.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1015260_4	1254432.SCE1572_30720	1.429e-99	332.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SHD3_k127_1015260_1	1254432.SCE1572_04355	2.356e-109	366.0	COG1752@1|root,COG1752@2|Bacteria,1R7RX@1224|Proteobacteria,4379P@68525|delta/epsilon subdivisions,2X9XU@28221|Deltaproteobacteria,2Z1Y1@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SHD3_k127_1015260_0	448385.sce0639	2.288e-231	726.0	COG0029@1|root,COG0029@2|Bacteria,1RBQW@1224|Proteobacteria,43BKD@68525|delta/epsilon subdivisions,2WJNK@28221|Deltaproteobacteria,2YUGG@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of L-aspartate to iminoaspartate	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SHD3_k127_1015260_2	1192034.CAP_5012	3.148e-108	357.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,42PYM@68525|delta/epsilon subdivisions,2WJ37@28221|Deltaproteobacteria,2Z31S@29|Myxococcales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SHD3_k127_1015260_3	1192034.CAP_5013	1.282e-104	349.0	COG2025@1|root,COG2025@2|Bacteria,1MUFI@1224|Proteobacteria,42M3T@68525|delta/epsilon subdivisions,2WIV8@28221|Deltaproteobacteria,2YUPZ@29|Myxococcales	28221|Deltaproteobacteria	C	Electron transfer flavoprotein	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
SHD3_k127_1015260_5	1192034.CAP_3979	3.211e-92	323.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_3979|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1015260_6	1254432.SCE1572_00330	5.306e-40	163.0	COG3628@1|root,COG3628@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1015260_8	448385.sce2055	4.408e-29	130.0	COG3055@1|root,COG3203@1|root,COG3055@2|Bacteria,COG3203@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1016090_2	192952.MM_0984	5.301e-08	63.0	COG2043@1|root,arCOG02289@2157|Archaea,2XXDE@28890|Euryarchaeota,2NB2B@224756|Methanomicrobia	224756|Methanomicrobia	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
SHD3_k127_1016090_0	1382305.AZUC01000045_gene1380	5.28e-23	102.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,4HKGZ@91061|Bacilli	91061|Bacilli	S	Belongs to the UPF0145 family	ybjQ	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
SHD3_k127_1016090_1	378806.STAUR_5788	2.457e-17	92.0	COG1413@1|root,COG1413@2|Bacteria,1P8HR@1224|Proteobacteria,438W3@68525|delta/epsilon subdivisions,2X41M@28221|Deltaproteobacteria,2YXYY@29|Myxococcales	28221|Deltaproteobacteria	C	Lipoprotein amino terminal region	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_10184_3	287986.DV20_11960	6.249e-52	196.0	COG3386@1|root,COG3386@2|Bacteria,2HEKE@201174|Actinobacteria,4E1U8@85010|Pseudonocardiales	201174|Actinobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SHD3_k127_10184_4	391038.Bphy_4801	3.522e-37	144.0	COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,2VJY0@28216|Betaproteobacteria,1KGVR@119060|Burkholderiaceae	28216|Betaproteobacteria	E	alcohol dehydrogenase	fdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
SHD3_k127_10184_7	983917.RGE_22640	2.754e-23	103.0	COG5637@1|root,COG5637@2|Bacteria,1N6H4@1224|Proteobacteria,2VV0W@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Cyclase dehydrase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_10184_2	1192034.CAP_4239	4.171e-99	346.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	2|Bacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_10184_5	436308.Nmar_1463	6.33e-37	144.0	COG3324@1|root,arCOG04946@2157|Archaea	436308.Nmar_1463|-	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	-
SHD3_k127_10184_8	515635.Dtur_1305	3.091e-14	87.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin,Trypsin_2
SHD3_k127_10184_1	882.DVU_1778	4.169e-110	374.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7Z@28221|Deltaproteobacteria,2M8HE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
SHD3_k127_10184_0	706587.Desti_3607	6.178e-216	686.0	COG0174@1|root,COG0174@2|Bacteria,1MUGQ@1224|Proteobacteria,42M7A@68525|delta/epsilon subdivisions,2WJ8P@28221|Deltaproteobacteria,2MR6S@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	TIGRFAM glutamine synthetase, type I	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SHD3_k127_10184_6	448385.sce7211	4.646e-27	128.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2YVH0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SHD3_k127_102529_2	1254432.SCE1572_21360	1.943e-11	71.0	COG0790@1|root,COG0790@2|Bacteria,1PFNI@1224|Proteobacteria,4346V@68525|delta/epsilon subdivisions,2X58N@28221|Deltaproteobacteria,2Z09P@29|Myxococcales	28221|Deltaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
SHD3_k127_102529_3	398512.JQKC01000007_gene1223	5.49e-09	62.0	COG0726@1|root,COG3693@1|root,COG0726@2|Bacteria,COG3693@2|Bacteria,1TT17@1239|Firmicutes,24CQR@186801|Clostridia,3WHVK@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 11	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_6,Dockerin_1,Glyco_hydro_10,Glyco_hydro_11,Polysacc_deac_1
SHD3_k127_102529_0	203119.Cthe_1963	3.78e-60	226.0	COG2382@1|root,COG3507@1|root,COG3693@1|root,COG2382@2|Bacteria,COG3507@2|Bacteria,COG3693@2|Bacteria,1TT7Q@1239|Firmicutes,24C1T@186801|Clostridia,3WJ0N@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the glycosyl hydrolase 43 family	-	GO:0003674,GO:0003824,GO:0004553,GO:0016787,GO:0016798,GO:0031176,GO:0033905,GO:0097599	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Dockerin_1,Esterase,Glyco_hydro_11
SHD3_k127_102529_1	1463917.JODC01000003_gene5830	1.807e-12	73.0	COG3693@1|root,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	xynA2	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,Glyco_hydro_10,Ricin_B_lectin
SHD3_k127_1027501_4	1237149.C900_05849	5.562e-14	72.0	COG5487@1|root,COG5487@2|Bacteria,4NXPG@976|Bacteroidetes,47T5C@768503|Cytophagia	976|Bacteroidetes	S	Protein of unknown function (DUF1328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1328
SHD3_k127_1027501_1	1128421.JAGA01000002_gene1203	5.435e-120	395.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_1027501_0	1183438.GKIL_0310	2.461e-181	584.0	COG0433@1|root,COG0561@1|root,COG0433@2|Bacteria,COG0561@2|Bacteria,1G3GC@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,Hydrolase_3
SHD3_k127_1027501_2	1463825.JNXC01000004_gene4243	3.712e-82	280.0	COG2129@1|root,COG2129@2|Bacteria,2GJ72@201174|Actinobacteria,4DXKD@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SHD3_k127_1027501_5	208439.AJAP_23480	5.855e-09	65.0	2DM23@1|root,31DUR@2|Bacteria,2GIYZ@201174|Actinobacteria,4DYWQ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,DUF2204,NTP_transf_5
SHD3_k127_1027501_3	1041930.Mtc_2227	4.355e-27	120.0	COG4914@1|root,arCOG04119@2157|Archaea	2157|Archaea	S	PFAM Conserved Archaeal protein (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204,NTP_transf_5
SHD3_k127_1051725_2	378806.STAUR_7509	4.241e-54	196.0	2EGHW@1|root,33A9Z@2|Bacteria,1PM4Y@1224|Proteobacteria,43304@68525|delta/epsilon subdivisions,2WYJA@28221|Deltaproteobacteria,2Z1SV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1051725_0	1192034.CAP_2387	4.184e-235	760.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,2YUND@29|Myxococcales	28221|Deltaproteobacteria	P	PEGA domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
SHD3_k127_1051725_1	448385.sce4512	6.664e-91	319.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1061318_15	1177154.Y5S_00213	4.737e-61	221.0	COG3076@1|root,COG3076@2|Bacteria,1N195@1224|Proteobacteria,1SD9D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Family of unknown function (DUF695)	-	-	-	-	-	-	-	-	-	-	-	-	DUF695,RraB
SHD3_k127_1061318_16	290397.Adeh_2053	1.858e-52	199.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	2.1.1.187	ko:K00563	-	-	R07233	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SHD3_k127_1061318_13	448385.sce9208	6.835e-65	245.0	2DRH1@1|root,33BQ8@2|Bacteria,1NM8D@1224|Proteobacteria,42XND@68525|delta/epsilon subdivisions,2WSKN@28221|Deltaproteobacteria,2YW71@29|Myxococcales	28221|Deltaproteobacteria	-	-	gspN	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
SHD3_k127_1061318_7	448385.sce9210	7.275e-109	369.0	COG4972@1|root,COG4972@2|Bacteria,1MYIB@1224|Proteobacteria,42SIX@68525|delta/epsilon subdivisions,2WP1G@28221|Deltaproteobacteria,2YVKD@29|Myxococcales	28221|Deltaproteobacteria	NU	Type IV pilus assembly protein PilM;	gspL	-	-	ko:K02461	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	GspL_C,PilM_2,PilN,T2SSL
SHD3_k127_1061318_8	1192034.CAP_6340	2.736e-100	351.0	COG3156@1|root,COG3156@2|Bacteria,1RIW9@1224|Proteobacteria,42V6H@68525|delta/epsilon subdivisions,2X2BW@28221|Deltaproteobacteria,2YVV7@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein K	gspK	-	-	ko:K02460	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSK
SHD3_k127_1061318_14	1192034.CAP_6341	6.042e-62	222.0	COG4795@1|root,COG4795@2|Bacteria,1NPEC@1224|Proteobacteria,42WZG@68525|delta/epsilon subdivisions,2WSPB@28221|Deltaproteobacteria,2YVMW@29|Myxococcales	28221|Deltaproteobacteria	U	Type II secretion system (T2SS), protein J	gspJ	-	-	ko:K02459	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSJ
SHD3_k127_1061318_21	448385.sce9213	2.778e-43	176.0	COG4967@1|root,COG4967@2|Bacteria,1QUS3@1224|Proteobacteria,42X07@68525|delta/epsilon subdivisions,2WSQI@28221|Deltaproteobacteria,2YW2A@29|Myxococcales	28221|Deltaproteobacteria	U	Prokaryotic N-terminal methylation motif	gspI	-	-	ko:K02458	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SHD3_k127_1061318_19	1254432.SCE1572_51975	8.989e-45	171.0	COG4970@1|root,COG4970@2|Bacteria,1QZTS@1224|Proteobacteria,43CNR@68525|delta/epsilon subdivisions,2X7W1@28221|Deltaproteobacteria,2Z3IR@29|Myxococcales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02457	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl
SHD3_k127_1061318_26	448385.sce9215	3.074e-18	95.0	COG2165@1|root,COG2165@2|Bacteria,1RDX2@1224|Proteobacteria,42SFB@68525|delta/epsilon subdivisions,2WP3B@28221|Deltaproteobacteria,2YW2T@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein G	gspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SHD3_k127_1061318_5	448385.sce9217	4.938e-159	512.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42MH9@68525|delta/epsilon subdivisions,2WJE0@28221|Deltaproteobacteria,2YTZT@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein F	gspF	-	-	ko:K02455,ko:K02653	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	T2SSF
SHD3_k127_1061318_0	448385.sce9218	2.541e-238	758.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YUKY@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	gspE	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SHD3_k127_1061318_1	448385.sce9219	5.282e-236	769.0	COG1450@1|root,COG4796@1|root,COG1450@2|Bacteria,COG4796@2|Bacteria,1MUUA@1224|Proteobacteria,42M9I@68525|delta/epsilon subdivisions,2WK1H@28221|Deltaproteobacteria,2YUDZ@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II and III secretion system protein	gspD	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin,Secretin_N
SHD3_k127_1061318_9	1254432.SCE1572_52010	1.341e-81	282.0	COG3031@1|root,COG3031@2|Bacteria,1NB50@1224|Proteobacteria,42WPG@68525|delta/epsilon subdivisions,2WREX@28221|Deltaproteobacteria,2YVJ9@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
SHD3_k127_1061318_3	1192034.CAP_6352	7.587e-221	693.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJU@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_1061318_18	391625.PPSIR1_26026	4.725e-45	174.0	2A20V@1|root,30QAU@2|Bacteria,1RDQH@1224|Proteobacteria,4330X@68525|delta/epsilon subdivisions,2WXN7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1061318_28	404589.Anae109_2744	1.227e-10	72.0	2AJ10@1|root,319J4@2|Bacteria,1Q2X4@1224|Proteobacteria,438K5@68525|delta/epsilon subdivisions,2X3UQ@28221|Deltaproteobacteria,2YX5Z@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1061318_2	1048339.KB913029_gene1974	4.972e-226	710.0	COG0017@1|root,COG0017@2|Bacteria,2HFYJ@201174|Actinobacteria,4EWHK@85013|Frankiales	201174|Actinobacteria	J	tRNA synthetases class II (D, K and N)	-	-	6.1.1.23	ko:K09759	ko00970,map00970	M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
SHD3_k127_1061318_25	448385.sce9225	2.97e-27	128.0	COG3411@1|root,COG3411@2|Bacteria,1RM68@1224|Proteobacteria,42TUK@68525|delta/epsilon subdivisions,2WQGU@28221|Deltaproteobacteria,2YVQK@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1061318_4	1192034.CAP_4257	1.165e-167	541.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2YU21@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
SHD3_k127_1061318_17	1278073.MYSTI_08009	1.115e-45	184.0	COG0642@1|root,COG3447@1|root,COG2205@2|Bacteria,COG3447@2|Bacteria,1QX6V@1224|Proteobacteria,43BZK@68525|delta/epsilon subdivisions,2X7AC@28221|Deltaproteobacteria,2YZ6E@29|Myxococcales	28221|Deltaproteobacteria	T	MASE1	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE1
SHD3_k127_1061318_6	443143.GM18_0169	1.582e-125	423.0	COG2812@1|root,COG2812@2|Bacteria,1MVCK@1224|Proteobacteria,42M09@68525|delta/epsilon subdivisions,2WJ1G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
SHD3_k127_1061318_10	1254432.SCE1572_02185	3.701e-81	274.0	COG0353@1|root,COG0353@2|Bacteria,1MV9Q@1224|Proteobacteria,42QZJ@68525|delta/epsilon subdivisions,2WNCH@28221|Deltaproteobacteria,2YYNH@29|Myxococcales	28221|Deltaproteobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
SHD3_k127_1061318_22	479434.Sthe_1579	2.456e-41	162.0	COG0251@1|root,COG0251@2|Bacteria,2G6XT@200795|Chloroflexi,27YDZ@189775|Thermomicrobia	189775|Thermomicrobia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
SHD3_k127_1061318_12	448385.sce0255	1.259e-72	260.0	COG1158@1|root,COG1158@2|Bacteria	2|Bacteria	K	DNA-templated transcription, termination	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,G5,YSIRK_signal
SHD3_k127_1061318_24	278957.ABEA03000019_gene1865	2.83e-29	127.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SHD3_k127_1061318_27	215803.DB30_4072	1.769e-14	87.0	COG3064@1|root,COG3064@2|Bacteria,1QX6Z@1224|Proteobacteria,43BZQ@68525|delta/epsilon subdivisions,2X7AH@28221|Deltaproteobacteria,2YZHQ@29|Myxococcales	28221|Deltaproteobacteria	M	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SHD3_k127_1061318_11	397945.Aave_1288	1.933e-75	263.0	COG0463@1|root,COG0463@2|Bacteria,1P8G7@1224|Proteobacteria,2VTB4@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_1064302_3	448385.sce0838	2.435e-69	237.0	COG0048@1|root,COG0048@2|Bacteria,1RCWY@1224|Proteobacteria,42RDQ@68525|delta/epsilon subdivisions,2WND8@28221|Deltaproteobacteria,2YV8E@29|Myxococcales	28221|Deltaproteobacteria	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
SHD3_k127_1064302_2	448385.sce0839	3.408e-82	274.0	COG0049@1|root,COG0049@2|Bacteria,1MXC8@1224|Proteobacteria,42QR7@68525|delta/epsilon subdivisions,2WNFM@28221|Deltaproteobacteria,2YUYC@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
SHD3_k127_1064302_0	1254432.SCE1572_05920	0.0	1050.0	COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,42M4T@68525|delta/epsilon subdivisions,2WIM7@28221|Deltaproteobacteria,2YUNN@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SHD3_k127_1064302_1	1254432.SCE1572_05925	1.299e-102	340.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2YX6I@29|Myxococcales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SHD3_k127_1073073_2	1177179.A11A3_05254	3.282e-78	267.0	COG5184@1|root,COG5276@1|root,COG5184@2|Bacteria,COG5276@2|Bacteria,1QUHA@1224|Proteobacteria,1T1YV@1236|Gammaproteobacteria,1XS25@135619|Oceanospirillales	135619|Oceanospirillales	DZ	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	TSP_3
SHD3_k127_1073073_0	1254432.SCE1572_16890	6.665e-151	496.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6Z3@28221|Deltaproteobacteria,2YYI1@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma54_activat
SHD3_k127_1073073_3	448385.sce5880	5.573e-52	207.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_1073073_4	1254432.SCE1572_14920	2.737e-38	160.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_14920|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1073073_1	448385.sce4512	6.089e-93	323.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1073073_5	215803.DB30_3870	8.045e-15	84.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2X240@28221|Deltaproteobacteria,2YZXU@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_1097436_14	685727.REQ_07970	0.0009642	46.0	COG2515@1|root,COG2515@2|Bacteria,2GIV5@201174|Actinobacteria,4FZDF@85025|Nocardiaceae	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SHD3_k127_1097436_3	448385.sce7212	3.95e-208	678.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria	448385.sce7212|-	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1097436_8	448385.sce7213	1.045e-70	245.0	COG1670@1|root,COG1670@2|Bacteria,1PEJD@1224|Proteobacteria,43DWD@68525|delta/epsilon subdivisions,2WZ1V@28221|Deltaproteobacteria,2Z2FW@29|Myxococcales	28221|Deltaproteobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	ko:K03817	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
SHD3_k127_1097436_13	404589.Anae109_2980	9.725e-23	106.0	COG1309@1|root,COG1309@2|Bacteria,1PXCP@1224|Proteobacteria,43E0C@68525|delta/epsilon subdivisions,2WZC8@28221|Deltaproteobacteria,2Z1TT@29|Myxococcales	28221|Deltaproteobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_1097436_1	1192034.CAP_3938	5.409e-226	706.0	COG1260@1|root,COG1260@2|Bacteria,1N0D9@1224|Proteobacteria,42NWK@68525|delta/epsilon subdivisions,2WM2T@28221|Deltaproteobacteria,2YYFZ@29|Myxococcales	28221|Deltaproteobacteria	I	synthase	-	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth,NAD_binding_5
SHD3_k127_1097436_9	1254432.SCE1572_23115	9.788e-53	198.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SHD3_k127_1097436_4	215803.DB30_5750	4.986e-127	437.0	COG4258@1|root,COG4258@2|Bacteria,1QX7Z@1224|Proteobacteria,43C13@68525|delta/epsilon subdivisions,2X7BR@28221|Deltaproteobacteria,2YU55@29|Myxococcales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SHD3_k127_1097436_6	1192034.CAP_3144	1.625e-90	312.0	COG0558@1|root,COG2246@1|root,COG0558@2|Bacteria,COG2246@2|Bacteria,1N9TT@1224|Proteobacteria,42V2Q@68525|delta/epsilon subdivisions,2WRYY@28221|Deltaproteobacteria,2YWYE@29|Myxococcales	28221|Deltaproteobacteria	I	GtrA-like protein	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf,GtrA
SHD3_k127_1097436_12	1123073.KB899241_gene3187	4.419e-23	106.0	COG1267@1|root,COG1267@2|Bacteria,1MZJA@1224|Proteobacteria,1S68A@1236|Gammaproteobacteria,1X6TJ@135614|Xanthomonadales	135614|Xanthomonadales	I	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)	-	-	3.1.3.27	ko:K01095	ko00564,ko01100,map00564,map01100	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	PgpA
SHD3_k127_1097436_10	459349.CLOAM0286	9.064e-43	173.0	COG1409@1|root,COG1409@2|Bacteria,2NRSG@2323|unclassified Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N
SHD3_k127_1097436_5	1122164.JHWF01000027_gene921	4.612e-92	331.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,1T553@1236|Gammaproteobacteria,1JEEF@118969|Legionellales	118969|Legionellales	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SHD3_k127_1097436_2	344747.PM8797T_18741	8.078e-220	695.0	COG2759@1|root,COG2759@2|Bacteria,2IX40@203682|Planctomycetes	203682|Planctomycetes	F	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
SHD3_k127_1097436_0	1192034.CAP_8845	8.973e-284	915.0	COG4775@1|root,COG4775@2|Bacteria,1RJPJ@1224|Proteobacteria,42TA2@68525|delta/epsilon subdivisions,2WP1H@28221|Deltaproteobacteria,2YZDW@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
SHD3_k127_1097436_7	1158318.ATXC01000001_gene398	1.025e-85	287.0	COG0788@1|root,COG0788@2|Bacteria,2G3PV@200783|Aquificae	200783|Aquificae	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
SHD3_k127_1101954_1	1303518.CCALI_00693	8.071e-65	243.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	-	-	-	-	-	-	-	-	-	-	-	-	HSP70,MreB_Mbl
SHD3_k127_1101954_0	378806.STAUR_0531	0.0	1247.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42Z54@68525|delta/epsilon subdivisions,2WUB9@28221|Deltaproteobacteria,2YYC4@29|Myxococcales	28221|Deltaproteobacteria	J	Anticodon-binding domain of tRNA	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SHD3_k127_1102511_7	1254432.SCE1572_34555	2.281e-05	51.0	COG2885@1|root,COG2885@2|Bacteria,1QA7T@1224|Proteobacteria,434W4@68525|delta/epsilon subdivisions,2WZ74@28221|Deltaproteobacteria,2Z1GX@29|Myxococcales	28221|Deltaproteobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1102511_4	1033732.CAHI01000024_gene786	2.969e-40	159.0	COG0266@1|root,COG0266@2|Bacteria,4NIT4@976|Bacteroidetes,2FPIR@200643|Bacteroidia	976|Bacteroidetes	L	Formamidopyrimidine-DNA glycosylase H2TH domain	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SHD3_k127_1102511_0	1191523.MROS_1644	1.935e-244	784.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	xylS	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14
SHD3_k127_1102511_3	1163617.SCD_n01023	2.077e-76	263.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria,2VHGP@28216|Betaproteobacteria	28216|Betaproteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	ubiG	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_23
SHD3_k127_1102511_1	518766.Rmar_2616	1.456e-193	624.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1FIS9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_1102511_2	203119.Cthe_0825	1.596e-149	504.0	COG3291@1|root,COG3291@2|Bacteria,1UITX@1239|Firmicutes,25ERK@186801|Clostridia,3WSIM@541000|Ruminococcaceae	186801|Clostridia	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Dockerin_1,Glyco_hydro_9
SHD3_k127_1102511_5	448385.sce4181	1.047e-20	108.0	2AN2E@1|root,31CZZ@2|Bacteria,1QA0W@1224|Proteobacteria,434RF@68525|delta/epsilon subdivisions,2WZ2M@28221|Deltaproteobacteria,2Z16X@29|Myxococcales	448385.sce4181|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1102511_8	570268.ANBB01000033_gene2147	3.936e-05	56.0	COG1413@1|root,COG1413@2|Bacteria,2GITU@201174|Actinobacteria	201174|Actinobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_1102511_9	693661.Arcve_1469	4.738e-05	55.0	COG5635@1|root,arCOG02967@2157|Archaea,2Y7N5@28890|Euryarchaeota	28890|Euryarchaeota	T	PBS lyase HEAT domain protein repeat-containing protein	-	-	-	ko:K22221	-	-	-	-	ko00000	-	-	-	HEAT_2,HEAT_PBS,NACHT
SHD3_k127_1103085_5	697282.Mettu_0616	1.616e-63	224.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales	135618|Methylococcales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
SHD3_k127_1103085_3	1254432.SCE1572_51360	8.154e-135	454.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria,2YU4W@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SHD3_k127_1103085_8	289377.HL41_06410	1.957e-32	130.0	COG0369@1|root,COG1151@2|Bacteria,2GHBI@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	P	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
SHD3_k127_1103085_6	631362.Thi970DRAFT_00749	5.425e-47	173.0	COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,1S26H@1236|Gammaproteobacteria,1WY18@135613|Chromatiales	135613|Chromatiales	S	PFAM Amino acid-binding ACT	-	-	-	-	-	-	-	-	-	-	-	-	ACT
SHD3_k127_1103085_1	768671.ThimaDRAFT_0592	3.064e-211	665.0	COG1541@1|root,COG1541@2|Bacteria,1MV1W@1224|Proteobacteria,1RQ3D@1236|Gammaproteobacteria,1WWR9@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)	-	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
SHD3_k127_1103085_7	765910.MARPU_13880	7.74e-44	165.0	COG1014@1|root,COG1014@2|Bacteria,1RH9B@1224|Proteobacteria,1S352@1236|Gammaproteobacteria,1WY47@135613|Chromatiales	135613|Chromatiales	C	PFAM Pyruvate	-	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
SHD3_k127_1103085_0	404589.Anae109_0043	1.487e-211	671.0	COG4231@1|root,COG4231@2|Bacteria,1MUKS@1224|Proteobacteria,42N44@68525|delta/epsilon subdivisions,2WIX6@28221|Deltaproteobacteria,2Z24J@29|Myxococcales	28221|Deltaproteobacteria	C	Indolepyruvate ferredoxin oxidoreductase	iorA-1	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
SHD3_k127_1103085_4	1192034.CAP_7394	4.848e-107	354.0	COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,42RAF@68525|delta/epsilon subdivisions,2WN7G@28221|Deltaproteobacteria,2Z09C@29|Myxococcales	28221|Deltaproteobacteria	H	Site-specific DNA-methyltransferase (Adenine-specific)	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SHD3_k127_1103085_2	443143.GM18_2713	8.446e-148	490.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,42M8I@68525|delta/epsilon subdivisions,2WJGH@28221|Deltaproteobacteria,43TRM@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
SHD3_k127_1104139_5	448385.sce1159	1.896e-30	138.0	COG2911@1|root,COG2911@2|Bacteria,1N4HK@1224|Proteobacteria,438QH@68525|delta/epsilon subdivisions,2X912@28221|Deltaproteobacteria,2YXIA@29|Myxococcales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1104139_8	1125863.JAFN01000001_gene1096	4.411e-17	89.0	COG0655@1|root,COG0655@2|Bacteria,1RD5X@1224|Proteobacteria,42T3S@68525|delta/epsilon subdivisions,2WN9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SHD3_k127_1104139_4	448385.sce3020	5.87e-54	199.0	2AMW0@1|root,31CSU@2|Bacteria,1Q9ME@1224|Proteobacteria,434GQ@68525|delta/epsilon subdivisions,2WYU2@28221|Deltaproteobacteria,2Z0M8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1104139_3	665571.STHERM_c16550	5.328e-77	272.0	COG0451@1|root,COG0451@2|Bacteria,2J8I0@203691|Spirochaetes	203691|Spirochaetes	M	NAD(P)H-binding	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SHD3_k127_1104139_2	391625.PPSIR1_16355	3.664e-90	306.0	2DBF0@1|root,2Z8VT@2|Bacteria,1RJQR@1224|Proteobacteria	1224|Proteobacteria	S	3-oxo-5-alpha-steroid 4-dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Steroid_dh
SHD3_k127_1104139_7	1408424.JHYI01000013_gene1101	1.699e-22	105.0	COG1309@1|root,COG1309@2|Bacteria,1VCZS@1239|Firmicutes,4HKIW@91061|Bacilli,1ZDZA@1386|Bacillus	91061|Bacilli	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K16137	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_13,TetR_N
SHD3_k127_1104139_0	1192034.CAP_5247	5.725e-152	504.0	COG3973@1|root,COG3973@2|Bacteria,1P638@1224|Proteobacteria,42MXR@68525|delta/epsilon subdivisions,2WK1Z@28221|Deltaproteobacteria,2Z32G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD_C_2
SHD3_k127_1108490_8	448385.sce3259	1.575e-60	220.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SHD3_k127_1108490_11	448385.sce2918	1.239e-15	91.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
SHD3_k127_1108490_2	404589.Anae109_3067	9.454e-144	483.0	COG1948@1|root,COG4880@2|Bacteria,1PQKR@1224|Proteobacteria,438JJ@68525|delta/epsilon subdivisions,2X3U8@28221|Deltaproteobacteria,2YX4D@29|Myxococcales	28221|Deltaproteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SHD3_k127_1108490_6	1220534.B655_1034	8.264e-64	243.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_1108490_4	1192034.CAP_3571	2.365e-129	430.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SHD3_k127_1108490_3	74547.PMT_0224	1.184e-132	430.0	COG0031@1|root,COG0031@2|Bacteria,1G493@1117|Cyanobacteria,1MKKG@1212|Prochloraceae	1117|Cyanobacteria	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK1	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SHD3_k127_1108490_1	448385.sce7473	1.06e-152	498.0	COG1672@1|root,COG1672@2|Bacteria,1R4NN@1224|Proteobacteria,42NMV@68525|delta/epsilon subdivisions,2WM2Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,AAA_35
SHD3_k127_1108490_0	448385.sce4195	5.923e-222	702.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2Z1PP@29|Myxococcales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM,TPR_1
SHD3_k127_1108490_9	1121413.JMKT01000017_gene441	1.692e-33	138.0	COG1324@1|root,COG1324@2|Bacteria,1N6TN@1224|Proteobacteria,42VE1@68525|delta/epsilon subdivisions,2WR7D@28221|Deltaproteobacteria,2MDG6@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM CutA1 divalent ion tolerance protein	cutA	-	-	ko:K03926	-	-	-	-	ko00000	-	-	-	CutA1
SHD3_k127_1108490_10	1254432.SCE1572_17010	3.027e-16	84.0	COG3793@1|root,COG3793@2|Bacteria	2|Bacteria	P	PFAM Mo-dependent nitrogenase	-	-	-	-	-	-	-	-	-	-	-	-	TerB
SHD3_k127_1108490_5	344747.PM8797T_09309	1.04e-64	235.0	COG0585@1|root,COG0585@2|Bacteria,2IYMT@203682|Planctomycetes	203682|Planctomycetes	J	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs	truD	-	5.4.99.27	ko:K06176	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruD
SHD3_k127_1108490_7	448385.sce3795	1.272e-60	224.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SHD3_k127_1120960_0	584708.Apau_1767	1.072e-62	229.0	2E1HS@1|root,32WVU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1120960_1	1123487.KB892865_gene1533	4.815e-14	72.0	COG2730@1|root,COG2730@2|Bacteria,1MV2T@1224|Proteobacteria,2VMFF@28216|Betaproteobacteria,2KYTZ@206389|Rhodocyclales	206389|Rhodocyclales	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_1121348_2	1304885.AUEY01000023_gene2687	2.511e-29	130.0	COG0826@1|root,COG0826@2|Bacteria	2|Bacteria	O	peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
SHD3_k127_1121348_1	1254432.SCE1572_43485	1.116e-57	213.0	COG2755@1|root,COG5297@1|root,COG2755@2|Bacteria,COG5297@2|Bacteria,1PFIY@1224|Proteobacteria,434S6@68525|delta/epsilon subdivisions,2WZ38@28221|Deltaproteobacteria,2Z1QH@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_1121348_0	1235788.C802_03144	1.795e-85	311.0	COG2605@1|root,COG2605@2|Bacteria,4NHF2@976|Bacteroidetes,2FMWG@200643|Bacteroidia,4AP97@815|Bacteroidaceae	976|Bacteroidetes	S	GHMP kinase, N-terminal domain protein	fkp	-	-	-	-	-	-	-	-	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
SHD3_k127_1132665_1	1501230.ET33_17595	1.197e-55	200.0	COG1247@1|root,COG1247@2|Bacteria,1VJ3A@1239|Firmicutes,4HRVQ@91061|Bacilli	91061|Bacilli	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SHD3_k127_1132665_2	1049564.TevJSym_bj00160	1.509e-49	198.0	COG3420@1|root,COG3420@2|Bacteria,1QWWH@1224|Proteobacteria	1224|Proteobacteria	P	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NosD,W_rich_C
SHD3_k127_1132665_3	1123258.AQXZ01000015_gene4468	1.185e-08	68.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4FU2W@85025|Nocardiaceae	201174|Actinobacteria	Q	Esterase PHB depolymerase	lpqC	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SHD3_k127_1132665_4	448385.sce0701	2.472e-07	59.0	2AG7T@1|root,316CY@2|Bacteria,1PXCS@1224|Proteobacteria,434FW@68525|delta/epsilon subdivisions,2WYTA@28221|Deltaproteobacteria,2Z0JQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1132665_0	290397.Adeh_3516	8.927e-170	552.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CHU_C,PKD,SprB
SHD3_k127_1134486_1	1192034.CAP_5347	3.787e-60	220.0	COG3291@1|root,COG3291@2|Bacteria,1QX66@1224|Proteobacteria,437XJ@68525|delta/epsilon subdivisions,2X37H@28221|Deltaproteobacteria,2YUQ0@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_cc
SHD3_k127_1134486_0	1123368.AUIS01000028_gene1324	2.285e-115	393.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	hydrolase family 65, central catalytic	ycjT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.64,3.2.1.28,5.4.2.6	ko:K01194,ko:K01838,ko:K04844,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
SHD3_k127_1153361_13	1192034.CAP_0009	1.28e-23	105.0	2AQ5Z@1|root,31FBG@2|Bacteria,1PCFM@1224|Proteobacteria,43E4N@68525|delta/epsilon subdivisions,2X980@28221|Deltaproteobacteria,2Z2HX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1153361_7	1192034.CAP_0008	5.27e-80	274.0	COG4464@1|root,COG4464@2|Bacteria,1R5E2@1224|Proteobacteria,42UBJ@68525|delta/epsilon subdivisions,2WQ5M@28221|Deltaproteobacteria,2YVNX@29|Myxococcales	28221|Deltaproteobacteria	GM	PFAM PHP domain protein	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
SHD3_k127_1153361_6	1192034.CAP_5045	3.922e-83	288.0	COG0392@1|root,COG0392@2|Bacteria,1PPSZ@1224|Proteobacteria,434R6@68525|delta/epsilon subdivisions,2WZ2B@28221|Deltaproteobacteria,2Z16A@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SHD3_k127_1153361_14	448385.sce1059	9.194e-16	83.0	2A7HH@1|root,30WF4@2|Bacteria,1QATQ@1224|Proteobacteria,435AN@68525|delta/epsilon subdivisions,2WZMS@28221|Deltaproteobacteria,2Z2E3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1153361_3	448385.sce3799	7.97e-108	363.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_8
SHD3_k127_1153361_8	1254432.SCE1572_22880	3.555e-68	243.0	COG1262@1|root,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,434N1@68525|delta/epsilon subdivisions,2WYZF@28221|Deltaproteobacteria,2Z0ZV@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_1153361_12	767434.Fraau_2333	7.015e-30	124.0	COG0565@1|root,COG0565@2|Bacteria,1N47Y@1224|Proteobacteria,1RPD3@1236|Gammaproteobacteria,1X4VZ@135614|Xanthomonadales	135614|Xanthomonadales	J	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA	trmJ	-	2.1.1.200	ko:K15396	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SHD3_k127_1153361_4	1192034.CAP_7898	8.038e-92	318.0	COG1716@1|root,COG1716@2|Bacteria,1QH9U@1224|Proteobacteria,434RS@68525|delta/epsilon subdivisions,2WZ2V@28221|Deltaproteobacteria,2Z17M@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_1153361_1	448385.sce2040	1.496e-132	434.0	COG0631@1|root,COG0631@2|Bacteria,1NCRX@1224|Proteobacteria,43ABC@68525|delta/epsilon subdivisions,2X2PV@28221|Deltaproteobacteria,2Z0FJ@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SHD3_k127_1153361_9	1192034.CAP_7901	5.802e-65	241.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria	1224|Proteobacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02033,ko:K13890	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	BPD_transp_1
SHD3_k127_1153361_15	1329516.JPST01000005_gene1415	7.944e-14	84.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli,27B97@186824|Thermoactinomycetaceae	91061|Bacilli	EP	N-terminal TM domain of oligopeptide transport permease C	dppC	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SHD3_k127_1153361_5	1254432.SCE1572_12420	4.72e-84	283.0	COG0607@1|root,COG3118@1|root,COG0607@2|Bacteria,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	2.8.1.7,4.4.1.16	ko:K03671,ko:K05838,ko:K07390,ko:K11717	ko00450,ko01100,ko04621,ko05418,map00450,map01100,map04621,map05418	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000,ko03029,ko03110	-	-	-	Aminotran_5,Rhodanese,TPR_19,TPR_20,Thioredoxin
SHD3_k127_1153361_2	404589.Anae109_3145	2.971e-117	387.0	COG2461@1|root,COG2461@2|Bacteria,1R5J5@1224|Proteobacteria,42QAZ@68525|delta/epsilon subdivisions,2WQTR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	ko:K09155	-	-	-	-	ko00000	-	-	-	Hemerythrin,PAS_10
SHD3_k127_1153361_0	1499967.BAYZ01000119_gene3213	3.661e-157	509.0	COG0574@1|root,COG0574@2|Bacteria	2|Bacteria	G	Belongs to the PEP-utilizing enzyme family	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PPDK_N
SHD3_k127_1172204_4	1254432.SCE1572_25585	1.436e-46	179.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_25585|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1172204_2	448385.sce4215	3.129e-127	417.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2Z1G3@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SHD3_k127_1172204_1	502025.Hoch_3406	1.495e-136	451.0	COG1257@1|root,COG1257@2|Bacteria,1MXVE@1224|Proteobacteria,42R5Q@68525|delta/epsilon subdivisions,2WN6K@28221|Deltaproteobacteria,2YTT9@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the HMG-CoA reductase family	-	-	1.1.1.88	ko:K00054	ko00900,ko01110,ko01130,map00900,map01110,map01130	-	R02081	RC00004,RC00644	ko00000,ko00001,ko01000	-	-	-	HMG-CoA_red
SHD3_k127_1172204_0	1192034.CAP_6526	4.017e-171	554.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WK06@28221|Deltaproteobacteria,2YU3N@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SHD3_k127_1172204_3	1192034.CAP_6527	1.188e-124	408.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YTXZ@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SHD3_k127_119274_5	479431.Namu_3157	1.716e-19	102.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_119274_2	1192034.CAP_2442	1.08e-108	364.0	COG0395@1|root,COG0395@2|Bacteria,1MUWS@1224|Proteobacteria,42P8C@68525|delta/epsilon subdivisions,2WJ3R@28221|Deltaproteobacteria,2Z0SJ@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	ugpE	-	-	ko:K05815	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	BPD_transp_1
SHD3_k127_119274_3	1499967.BAYZ01000068_gene1927	1.021e-79	282.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	ugpA	-	-	ko:K02025,ko:K05814,ko:K15771	ko02010,map02010	M00198,M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2,3.A.1.1.3	-	-	BPD_transp_1
SHD3_k127_119274_0	448385.sce9264	2.396e-153	496.0	COG1653@1|root,COG1653@2|Bacteria,1MVMW@1224|Proteobacteria,42N79@68525|delta/epsilon subdivisions,2WM0N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K05813	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	SBP_bac_8
SHD3_k127_119274_1	448385.sce9263	1.426e-122	406.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,42NVJ@68525|delta/epsilon subdivisions,2WJN1@28221|Deltaproteobacteria,2YUG1@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
SHD3_k127_119274_4	1254432.SCE1572_20800	1.34e-30	131.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_119274_6	1173028.ANKO01000190_gene420	8.518e-06	54.0	2DRGP@1|root,33BNN@2|Bacteria,1GAY6@1117|Cyanobacteria,1HDTK@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_119274_7	9541.XP_005545180.1	0.0006232	49.0	2CZJA@1|root,2SAN0@2759|Eukaryota,3A3IY@33154|Opisthokonta,3BR7J@33208|Metazoa,3D5D9@33213|Bilateria,48BV0@7711|Chordata,4998I@7742|Vertebrata,3JG3B@40674|Mammalia,35E9W@314146|Euarchontoglires,4MGKX@9443|Primates,36713@314294|Cercopithecoidea	33208|Metazoa	T	Tumor necrosis factor receptor superfamily member 18	TNFRSF18	GO:0001932,GO:0001934,GO:0002237,GO:0002376,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002694,GO:0003674,GO:0004888,GO:0005031,GO:0005035,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006915,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0008150,GO:0008219,GO:0009605,GO:0009607,GO:0009617,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010033,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0012501,GO:0016020,GO:0016021,GO:0019220,GO:0019221,GO:0019222,GO:0023051,GO:0023052,GO:0023056,GO:0030155,GO:0030334,GO:0030335,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032268,GO:0032270,GO:0032496,GO:0032501,GO:0032502,GO:0032879,GO:0033209,GO:0033993,GO:0034097,GO:0034612,GO:0038023,GO:0040012,GO:0040017,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042509,GO:0042531,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0044425,GO:0044459,GO:0044464,GO:0045580,GO:0045589,GO:0045595,GO:0045619,GO:0045785,GO:0045937,GO:0046425,GO:0046427,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048856,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050863,GO:0050865,GO:0050896,GO:0051171,GO:0051173,GO:0051174,GO:0051239,GO:0051246,GO:0051247,GO:0051249,GO:0051270,GO:0051272,GO:0051704,GO:0051707,GO:0051716,GO:0060089,GO:0060255,GO:0060548,GO:0065007,GO:0070887,GO:0071310,GO:0071345,GO:0071356,GO:0071944,GO:0080090,GO:0097190,GO:0098552,GO:1901700,GO:1902105,GO:1902531,GO:1902533,GO:1903706,GO:1904892,GO:1904894,GO:2000026,GO:2000145,GO:2000147	-	ko:K05154	ko04060,map04060	-	-	-	ko00000,ko00001,ko04050,ko04090	-	-	-	TNFR_c6
SHD3_k127_1211636_3	448385.sce9032	6.751e-106	364.0	COG0500@1|root,COG2226@2|Bacteria,1MZIX@1224|Proteobacteria,43CDM@68525|delta/epsilon subdivisions,2X7PI@28221|Deltaproteobacteria,2YVQH@29|Myxococcales	28221|Deltaproteobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_1211636_1	1254432.SCE1572_51305	4.788e-137	444.0	COG0216@1|root,COG0216@2|Bacteria,1MV28@1224|Proteobacteria,42NA3@68525|delta/epsilon subdivisions,2WIQU@28221|Deltaproteobacteria,2YTSK@29|Myxococcales	28221|Deltaproteobacteria	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
SHD3_k127_1211636_6	443143.GM18_4160	5.058e-25	106.0	COG0254@1|root,COG0254@2|Bacteria,1PT0H@1224|Proteobacteria,42V2Z@68525|delta/epsilon subdivisions,2WRGA@28221|Deltaproteobacteria,43VM9@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
SHD3_k127_1211636_2	448385.sce1085	2.044e-122	404.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2Z073@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_1211636_0	1254432.SCE1572_07790	2.628e-218	693.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,1MY5M@1224|Proteobacteria,43BPV@68525|delta/epsilon subdivisions,2WJVS@28221|Deltaproteobacteria,2YW51@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
SHD3_k127_1211636_9	221288.JH992901_gene3952	2.778e-06	56.0	COG3744@1|root,COG3744@2|Bacteria,1G9VS@1117|Cyanobacteria,1JM9P@1189|Stigonemataceae	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_1211636_7	391625.PPSIR1_03608	5.472e-13	82.0	COG1708@1|root,COG1708@2|Bacteria,1NKZT@1224|Proteobacteria,430VC@68525|delta/epsilon subdivisions,2WVUS@28221|Deltaproteobacteria,2Z164@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
SHD3_k127_1211636_4	1297742.A176_03202	1.15e-46	191.0	29XGE@1|root,30J6W@2|Bacteria,1R0E6@1224|Proteobacteria,43CWN@68525|delta/epsilon subdivisions,2WUSC@28221|Deltaproteobacteria,2Z1N5@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1212966_1	1254432.SCE1572_22315	1.334e-56	220.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2YVAG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SHD3_k127_1212966_4	688269.Theth_1685	7.121e-34	137.0	28JE3@1|root,2Z98B@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SHD3_k127_1212966_5	1191523.MROS_0506	7.838e-23	110.0	COG2942@1|root,COG2942@2|Bacteria	2|Bacteria	G	2-epimerase	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
SHD3_k127_1212966_6	1121875.KB907546_gene2375	1.456e-18	93.0	COG2942@1|root,COG2942@2|Bacteria,4NEH7@976|Bacteroidetes,1HY0E@117743|Flavobacteriia	976|Bacteroidetes	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
SHD3_k127_1212966_2	391625.PPSIR1_11130	6.949e-53	204.0	COG1262@1|root,COG1262@2|Bacteria,1QADB@1224|Proteobacteria,43503@68525|delta/epsilon subdivisions,2X93Q@28221|Deltaproteobacteria,2Z1R3@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_1212966_3	1254432.SCE1572_33835	9.461e-51	192.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SHD3_k127_1212966_0	1192034.CAP_5076	2.762e-100	343.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_5076|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1222337_0	640081.Dsui_2049	1.228e-218	696.0	COG4178@1|root,COG4178@2|Bacteria,1MW09@1224|Proteobacteria,2VIMQ@28216|Betaproteobacteria,2KVDI@206389|Rhodocyclales	206389|Rhodocyclales	S	transport system, permease and ATPase	-	-	-	ko:K02471	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.203.11,3.A.1.203.4	-	-	ABC_membrane_2,ABC_tran
SHD3_k127_1222337_1	448385.sce5869	1.349e-94	321.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2Z07Q@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
SHD3_k127_1222337_2	208444.JNYY01000005_gene6669	1.491e-80	287.0	COG3420@1|root,COG3420@2|Bacteria,2I9HA@201174|Actinobacteria,4DXR8@85010|Pseudonocardiales	201174|Actinobacteria	P	Right handed beta helix region	wcoB	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565,NosD
SHD3_k127_122911_3	1192034.CAP_2970	2.927e-156	508.0	COG0790@1|root,COG0790@2|Bacteria,1PFNI@1224|Proteobacteria,4346V@68525|delta/epsilon subdivisions,2X58N@28221|Deltaproteobacteria,2Z09P@29|Myxococcales	28221|Deltaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
SHD3_k127_122911_1	1123368.AUIS01000032_gene1398	1.515e-199	644.0	COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Pfam SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	PLDc,PLDc_2,SNARE_assoc
SHD3_k127_122911_6	62928.azo1782	4.804e-78	267.0	COG3568@1|root,COG3568@2|Bacteria,1MVN7@1224|Proteobacteria,2VPRV@28216|Betaproteobacteria,2KYBD@206389|Rhodocyclales	206389|Rhodocyclales	L	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SHD3_k127_122911_4	1283300.ATXB01000001_gene664	1.879e-139	457.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1XFWC@135618|Methylococcales	135618|Methylococcales	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	hDGE_amylase
SHD3_k127_122911_0	1128421.JAGA01000003_gene3683	1.289e-205	657.0	COG5297@1|root,COG5297@2|Bacteria,2NQDB@2323|unclassified Bacteria	2|Bacteria	G	CBD_II	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_10,CBM_2,Glyco_hydro_6,PKD
SHD3_k127_122911_2	485913.Krac_5399	8.119e-173	561.0	COG3533@1|root,COG3533@2|Bacteria,2G7X9@200795|Chloroflexi	200795|Chloroflexi	S	COGs COG3533 conserved	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
SHD3_k127_122911_7	1144275.COCOR_01412	8.121e-66	230.0	COG3832@1|root,COG3832@2|Bacteria,1RA7N@1224|Proteobacteria,43DU9@68525|delta/epsilon subdivisions,2WYW3@28221|Deltaproteobacteria,2Z0S4@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SHD3_k127_122911_8	448385.sce1404	1.015e-48	175.0	COG0640@1|root,COG0640@2|Bacteria,1PG03@1224|Proteobacteria,434YR@68525|delta/epsilon subdivisions,2WZ9P@28221|Deltaproteobacteria,2Z0JU@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
SHD3_k127_122911_5	1192034.CAP_8441	1.167e-91	321.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
SHD3_k127_122911_9	1192034.CAP_8251	1.723e-06	55.0	COG1280@1|root,COG1280@2|Bacteria	2|Bacteria	E	homoserine transmembrane transporter activity	yahN	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039	-	ko:K03329,ko:K16327	-	-	-	-	ko00000,ko02000	2.A.76.1.3,2.A.76.1.6	-	-	LysE
SHD3_k127_1233538_2	211165.AJLN01000096_gene5033	1.411e-99	332.0	COG0364@1|root,COG0364@2|Bacteria,1GI0D@1117|Cyanobacteria,1JJHW@1189|Stigonemataceae	1117|Cyanobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	G6PD_C,G6PD_N
SHD3_k127_1233538_0	870187.Thini_1300	4.545e-197	633.0	COG1215@1|root,COG1215@2|Bacteria,1MWF8@1224|Proteobacteria,1RQ9P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Cellulose synthase	-	-	2.4.1.12	ko:K00694	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GT2	-	Cellulose_synt,Glycos_transf_2,PilZ
SHD3_k127_1233538_3	1188256.BASI01000001_gene523	1.31e-12	75.0	COG1366@1|root,COG1366@2|Bacteria,1MZE8@1224|Proteobacteria,2UBXI@28211|Alphaproteobacteria,3FEE7@34008|Rhodovulum	28211|Alphaproteobacteria	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SHD3_k127_1233538_1	518766.Rmar_2616	1.852e-184	595.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1FIS9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_1247444_4	767817.Desgi_2439	3.49e-79	275.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
SHD3_k127_1247444_1	1123373.ATXI01000004_gene1465	5.992e-161	515.0	COG0473@1|root,COG0473@2|Bacteria,2GGUW@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	CE	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SHD3_k127_1247444_7	398512.JQKC01000008_gene968	3.157e-49	180.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
SHD3_k127_1247444_3	1267535.KB906767_gene5203	1.565e-88	302.0	COG1063@1|root,COG1063@2|Bacteria,3Y7C5@57723|Acidobacteria	57723|Acidobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SHD3_k127_1247444_5	1254432.SCE1572_16105	2.726e-61	235.0	2ANE2@1|root,31DCP@2|Bacteria,1QAIW@1224|Proteobacteria,43E1I@68525|delta/epsilon subdivisions,2WZFD@28221|Deltaproteobacteria,2Z20M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1247444_6	269799.Gmet_3132	1.81e-55	201.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,43SW8@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SHD3_k127_1247444_0	156889.Mmc1_1678	1.267e-230	724.0	COG4108@1|root,COG4108@2|Bacteria,1MU7X@1224|Proteobacteria,2TRP5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
SHD3_k127_1247444_10	8932.XP_005507999.1	0.0001319	53.0	KOG4297@1|root,KOG4297@2759|Eukaryota,38GR9@33154|Opisthokonta,3BBE1@33208|Metazoa,3CTZ0@33213|Bilateria,4803E@7711|Chordata,492AY@7742|Vertebrata,4GUFV@8782|Aves	33208|Metazoa	TV	Macrophage mannose receptor 1-like	MRC1	GO:0002237,GO:0002376,GO:0003674,GO:0004888,GO:0005488,GO:0005537,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005886,GO:0005887,GO:0006810,GO:0006897,GO:0006898,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007165,GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009986,GO:0009987,GO:0010008,GO:0010033,GO:0012505,GO:0016020,GO:0016021,GO:0016192,GO:0023052,GO:0030246,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0032496,GO:0033993,GO:0034097,GO:0034341,GO:0036094,GO:0038023,GO:0038024,GO:0042221,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045087,GO:0048029,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0051716,GO:0060089,GO:0065007,GO:0070670,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071346,GO:0071353,GO:0071396,GO:0071944,GO:0097708,GO:0098588,GO:0098657,GO:0098805,GO:1901700,GO:1901701	-	ko:K06560	ko04145,ko05152,map04145,map05152	-	-	-	ko00000,ko00001,ko04090,ko04091,ko04131	-	-	-	Lectin_C,Ricin_B_lectin,fn2
SHD3_k127_1247444_8	1183438.GKIL_3207	1.003e-44	181.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28,fn3
SHD3_k127_1247444_9	59463.ENSMLUP00000017786	1.815e-07	60.0	KOG4297@1|root,KOG4297@2759|Eukaryota,39YT3@33154|Opisthokonta,3BMCI@33208|Metazoa,3CVVA@33213|Bilateria,48BF5@7711|Chordata,48YMK@7742|Vertebrata,3JAM0@40674|Mammalia,4KQ3A@9397|Chiroptera	33208|Metazoa	TV	C-type lectin domain family 10, member	CLEC10A	GO:0002218,GO:0002220,GO:0002223,GO:0002246,GO:0002248,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006952,GO:0006954,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0009611,GO:0009987,GO:0016020,GO:0023052,GO:0030246,GO:0031347,GO:0031349,GO:0032501,GO:0042060,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0048771,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944,GO:0080134,GO:0090594,GO:0097709	-	ko:K06721,ko:K10063	ko04918,map04918	-	-	-	ko00000,ko00001,ko04090,ko04091,ko04147	-	-	-	Lectin_C,Lectin_N
SHD3_k127_1263633_0	1121459.AQXE01000002_gene1309	4.389e-114	380.0	COG0561@1|root,COG0561@2|Bacteria,1NUB1@1224|Proteobacteria,42YPI@68525|delta/epsilon subdivisions,2WTTG@28221|Deltaproteobacteria,2MAW3@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1263633_2	575540.Isop_1328	6.672e-31	140.0	COG2856@1|root,COG2856@2|Bacteria,2J2FQ@203682|Planctomycetes	203682|Planctomycetes	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1263633_3	945713.IALB_2177	2.268e-29	128.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SHD3_k127_1272895_3	1297742.A176_06634	1.606e-06	60.0	COG1413@1|root,COG1413@2|Bacteria,1P8HR@1224|Proteobacteria,438W3@68525|delta/epsilon subdivisions,2X41M@28221|Deltaproteobacteria,2YXYY@29|Myxococcales	28221|Deltaproteobacteria	C	Lipoprotein amino terminal region	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_1272895_2	7668.SPU_021126-tr	5.896e-11	78.0	KOG4297@1|root,KOG4297@2759|Eukaryota,39VZV@33154|Opisthokonta,3BNAM@33208|Metazoa	33208|Metazoa	TV	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	-	-	-	-	-	-	-	-	-	-	-	Lectin_C
SHD3_k127_1272895_1	1121396.KB892946_gene2917	3.189e-13	85.0	COG0823@1|root,COG3291@1|root,COG3591@1|root,COG4676@1|root,COG0823@2|Bacteria,COG3291@2|Bacteria,COG3591@2|Bacteria,COG4676@2|Bacteria	2|Bacteria	UW	Protein conserved in bacteria	lpqB	-	2.7.13.3	ko:K07654	ko02020,map02020	M00461	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	Germane,Gmad1
SHD3_k127_1272895_0	1254432.SCE1572_40970	5.788e-24	121.0	2F8GF@1|root,340V9@2|Bacteria,1NXZ0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1273552_7	215803.DB30_5550	4.838e-88	305.0	COG1502@1|root,COG1502@2|Bacteria,1MWUW@1224|Proteobacteria,43BFU@68525|delta/epsilon subdivisions,2X5HG@28221|Deltaproteobacteria,2YUGC@29|Myxococcales	28221|Deltaproteobacteria	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
SHD3_k127_1273552_4	1192034.CAP_8720	7.276e-147	477.0	COG1078@1|root,COG1078@2|Bacteria,1R5S2@1224|Proteobacteria,42Q9G@68525|delta/epsilon subdivisions,2WMIK@28221|Deltaproteobacteria,2YVEH@29|Myxococcales	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06885	-	-	-	-	ko00000	-	-	-	HD
SHD3_k127_1273552_13	448385.sce7337	1.349e-48	182.0	COG2974@1|root,COG2974@2|Bacteria,1RCUH@1224|Proteobacteria,42QVW@68525|delta/epsilon subdivisions,2WN5B@28221|Deltaproteobacteria,2YVP2@29|Myxococcales	28221|Deltaproteobacteria	L	May be involved in recombination	-	-	-	-	-	-	-	-	-	-	-	-	RdgC
SHD3_k127_1273552_12	448385.sce7338	1.047e-55	202.0	COG2974@1|root,COG2974@2|Bacteria,1N4GC@1224|Proteobacteria,42RPT@68525|delta/epsilon subdivisions,2WIWU@28221|Deltaproteobacteria,2YUX5@29|Myxococcales	28221|Deltaproteobacteria	L	Putative exonuclease, RdgC	-	-	-	ko:K03554	-	-	-	-	ko00000,ko03400	-	-	-	RdgC
SHD3_k127_1273552_10	1192034.CAP_8040	2.083e-74	263.0	2CDCQ@1|root,307SM@2|Bacteria,1QST3@1224|Proteobacteria,4355I@68525|delta/epsilon subdivisions,2WZGF@28221|Deltaproteobacteria,2Z23I@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1273552_0	768670.Calni_2058	0.0	1056.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GF76@200930|Deferribacteres	200930|Deferribacteres	G	PEP-utilising enzyme, mobile domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
SHD3_k127_1273552_9	1242864.D187_005515	3.417e-77	289.0	2AJ5K@1|root,319Q7@2|Bacteria,1Q3I8@1224|Proteobacteria,4340Y@68525|delta/epsilon subdivisions,2X4J1@28221|Deltaproteobacteria,2YZ44@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1273552_5	502025.Hoch_3456	3.568e-134	454.0	COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42MQS@68525|delta/epsilon subdivisions,2WINP@28221|Deltaproteobacteria,2YU7W@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	fadJ	-	1.1.1.35,4.2.1.17,5.1.2.3	ko:K01782	ko00071,ko00280,ko00281,ko00310,ko00362,ko00380,ko00410,ko00640,ko00650,ko00903,ko00930,ko01040,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00281,map00310,map00362,map00380,map00410,map00640,map00650,map00903,map00930,map01040,map01100,map01110,map01120,map01130,map01200,map01212	M00032,M00087	R01975,R03026,R03045,R03276,R04137,R04170,R04203,R04204,R04224,R04737,R04738,R04739,R04740,R04741,R04744,R04745,R04746,R04748,R04749,R05066,R05305,R06411,R06412,R06941,R06942,R07935,R07951,R08093,R08094	RC00029,RC00099,RC00117,RC00241,RC00525,RC00831,RC00834,RC00896,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	3HCDH,3HCDH_N,ECH_1
SHD3_k127_1273552_14	1192034.CAP_2998	1.898e-45	173.0	COG1309@1|root,COG1309@2|Bacteria,1MYFS@1224|Proteobacteria,42T8F@68525|delta/epsilon subdivisions,2WPCH@28221|Deltaproteobacteria,2Z34T@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_1273552_15	448385.sce6268	1.312e-29	120.0	COG2924@1|root,COG2924@2|Bacteria,1Q2JG@1224|Proteobacteria,433U0@68525|delta/epsilon subdivisions,2X9ZA@28221|Deltaproteobacteria,2YVYI@29|Myxococcales	28221|Deltaproteobacteria	C	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes	-	-	-	-	-	-	-	-	-	-	-	-	Iron_traffic
SHD3_k127_1273552_3	1192034.CAP_3394	2.398e-177	579.0	COG3408@1|root,COG3408@2|Bacteria,1MW01@1224|Proteobacteria,42NSN@68525|delta/epsilon subdivisions,2WJF7@28221|Deltaproteobacteria,2YX9T@29|Myxococcales	28221|Deltaproteobacteria	G	High confidence in function and specificity	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N
SHD3_k127_1273552_1	1121428.DESHY_110526___1	2e-323	1018.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,260NC@186807|Peptococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SHD3_k127_1273552_8	643648.Slip_1114	4.343e-87	295.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,42JHI@68298|Syntrophomonadaceae	186801|Clostridia	F	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SHD3_k127_1277483_9	880073.Calab_2213	1.356e-32	138.0	COG1609@1|root,COG1609@2|Bacteria,2NR26@2323|unclassified Bacteria	2|Bacteria	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SHD3_k127_1277483_1	1254432.SCE1572_15505	2.62e-137	467.0	COG0744@1|root,COG0744@2|Bacteria,1RDAQ@1224|Proteobacteria,42QW6@68525|delta/epsilon subdivisions,2WPZA@28221|Deltaproteobacteria,2YVC6@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors	mtgA	-	2.4.1.129	ko:K03814	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly
SHD3_k127_1277483_6	448385.sce2586	1.302e-55	201.0	COG0590@1|root,COG0590@2|Bacteria,1RGU0@1224|Proteobacteria,42TVP@68525|delta/epsilon subdivisions,2WQ7U@28221|Deltaproteobacteria,2YVEI@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
SHD3_k127_1277483_2	331113.SNE_A09680	2.187e-88	305.0	COG2220@1|root,COG2220@2|Bacteria,2JG2E@204428|Chlamydiae	204428|Chlamydiae	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SHD3_k127_1277483_0	1192034.CAP_6072	2.884e-157	509.0	COG0863@1|root,COG0863@2|Bacteria,1R9I2@1224|Proteobacteria,43B52@68525|delta/epsilon subdivisions,2WW0K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	-
SHD3_k127_1277483_4	448385.sce5172	6.119e-64	235.0	COG1082@1|root,COG1082@2|Bacteria,1PAMZ@1224|Proteobacteria	1224|Proteobacteria	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2
SHD3_k127_1277483_14	448385.sce6582	3.436e-14	84.0	2AN8E@1|root,31D6G@2|Bacteria,1QA9T@1224|Proteobacteria,434XI@68525|delta/epsilon subdivisions,2WZ8B@28221|Deltaproteobacteria,2Z1JP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1277483_12	290397.Adeh_1402	6.032e-23	106.0	COG3945@1|root,COG3945@2|Bacteria,1NG3G@1224|Proteobacteria,42WHU@68525|delta/epsilon subdivisions,2WRK5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SHD3_k127_1277483_16	1101191.KI912577_gene1757	2.981e-05	54.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,2TQXJ@28211|Alphaproteobacteria,1JS5Y@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	PDZ DHR GLGF domain protein	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SHD3_k127_1277483_15	1499502.EV12_0944	2.088e-12	70.0	2DYAZ@1|root,348ZI@2|Bacteria,1GF7Z@1117|Cyanobacteria,1MNUQ@1212|Prochloraceae	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1277483_8	1144275.COCOR_06533	2.39e-34	147.0	29Z4J@1|root,30M27@2|Bacteria,1Q3S3@1224|Proteobacteria,439K6@68525|delta/epsilon subdivisions,2X4WW@28221|Deltaproteobacteria,2YZRZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1277483_7	59374.Fisuc_1930	1.158e-39	159.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K07110,ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,DUF4423,HTH_3,HTH_31,Peptidase_M78
SHD3_k127_1277483_13	1192034.CAP_1515	2.206e-19	101.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_1277483_10	1120959.ATXF01000005_gene1379	2.11e-32	141.0	COG1819@1|root,COG1819@2|Bacteria,2I97R@201174|Actinobacteria	201174|Actinobacteria	CG	transferase activity, transferring hexosyl groups	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	-	-	-	-	-	-	-	-	-	Glyco_tran_28_C,UDPGT
SHD3_k127_1277483_11	1122915.AUGY01000005_gene5726	1.561e-28	134.0	COG3979@1|root,COG4733@1|root,COG3979@2|Bacteria,COG4733@2|Bacteria,1UNVG@1239|Firmicutes,4IUR5@91061|Bacilli,277PT@186822|Paenibacillaceae	91061|Bacilli	S	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1277483_5	1379698.RBG1_1C00001G1529	1.926e-59	232.0	COG2304@1|root,COG2304@2|Bacteria,2NPUS@2323|unclassified Bacteria	2|Bacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	M64_N,Peptidase_M64
SHD3_k127_1278637_14	102232.GLO73106DRAFT_00020540	4.849e-05	48.0	2EGZK@1|root,33ARQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1278637_2	448385.sce4543	1.106e-111	390.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,43ARV@68525|delta/epsilon subdivisions,2X65Y@28221|Deltaproteobacteria,2Z39J@29|Myxococcales	448385.sce4543|-	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SHD3_k127_1278637_7	1254432.SCE1572_33325	4.549e-49	197.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,42PUT@68525|delta/epsilon subdivisions,2WKN0@28221|Deltaproteobacteria,2YVT8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
SHD3_k127_1278637_3	1254432.SCE1572_27800	9.265e-92	318.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
SHD3_k127_1278637_6	926550.CLDAP_20910	6.206e-55	218.0	COG1319@1|root,COG3266@1|root,COG3391@1|root,COG1319@2|Bacteria,COG3266@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	FAD_binding_5
SHD3_k127_1278637_4	338963.Pcar_2239	1.055e-64	231.0	COG2188@1|root,COG2188@2|Bacteria,1MUEB@1224|Proteobacteria,42QNG@68525|delta/epsilon subdivisions,2WK8B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	UTRA domain	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
SHD3_k127_1278637_1	1121405.dsmv_2941	1.792e-214	670.0	COG0133@1|root,COG0133@2|Bacteria,1MUS8@1224|Proteobacteria,42MIA@68525|delta/epsilon subdivisions,2WJJA@28221|Deltaproteobacteria,2MHP8@213118|Desulfobacterales	28221|Deltaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SHD3_k127_1278637_5	44251.PDUR_05270	6.53e-61	221.0	COG0159@1|root,COG0159@2|Bacteria,1UZ3R@1239|Firmicutes,4HVBK@91061|Bacilli,26VPF@186822|Paenibacillaceae	91061|Bacilli	E	Tryptophan synthase alpha chain	-	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
SHD3_k127_1278637_9	1121920.AUAU01000015_gene1134	2.078e-48	183.0	COG1179@1|root,COG1179@2|Bacteria	2|Bacteria	H	involved in molybdopterin and THIamine biosynthesis family 1	ygdL	GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016829,GO:0016835,GO:0016836,GO:0030955,GO:0031402,GO:0031420,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0061503,GO:0061504,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.7.7.73,2.7.7.80	ko:K03148,ko:K21029,ko:K22132	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000,ko03016	-	-	-	ThiF
SHD3_k127_1278637_10	391625.PPSIR1_35387	5.085e-39	165.0	COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
SHD3_k127_1278637_11	1123368.AUIS01000033_gene1380	9.149e-27	128.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SHD3_k127_1278637_8	391625.PPSIR1_18632	1.768e-48	186.0	COG5297@1|root,COG5297@2|Bacteria,1NDMY@1224|Proteobacteria,4333K@68525|delta/epsilon subdivisions,2WXH7@28221|Deltaproteobacteria,2YXQH@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,CelD_N,Glyco_hydro_9
SHD3_k127_1278637_0	518766.Rmar_0317	1.952e-249	801.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,4NDWN@976|Bacteroidetes,1FIWU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	L	helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SHD3_k127_1278637_13	338966.Ppro_2623	8.445e-15	81.0	COG3668@1|root,COG3668@2|Bacteria,1N8NU@1224|Proteobacteria,42UWI@68525|delta/epsilon subdivisions,2WQYD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM plasmid stabilization system	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SHD3_k127_1278637_12	215803.DB30_7526	3.474e-20	92.0	COG2161@1|root,COG2161@2|Bacteria,1Q1K4@1224|Proteobacteria,43EY3@68525|delta/epsilon subdivisions,2XA1E@28221|Deltaproteobacteria,2Z1CV@29|Myxococcales	28221|Deltaproteobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SHD3_k127_1280565_15	448385.sce1041	3.145e-30	137.0	COG0760@1|root,COG0760@2|Bacteria,1MVB3@1224|Proteobacteria,42QXH@68525|delta/epsilon subdivisions,2WMN3@28221|Deltaproteobacteria,2YVIS@29|Myxococcales	28221|Deltaproteobacteria	M	SurA N-terminal domain	surA	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
SHD3_k127_1280565_12	1144275.COCOR_00637	7.005e-74	267.0	COG0515@1|root,COG0515@2|Bacteria,1P64D@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	pkn9	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1280565_13	391625.PPSIR1_18477	1.32e-37	153.0	COG3921@1|root,COG3921@2|Bacteria	2|Bacteria	S	Extensin-like protein C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
SHD3_k127_1280565_5	1254432.SCE1572_22505	1.538e-100	347.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_1280565_2	1192034.CAP_7257	4.241e-145	490.0	COG1470@1|root,COG1470@2|Bacteria,1P6QQ@1224|Proteobacteria,4385T@68525|delta/epsilon subdivisions,2X3FM@28221|Deltaproteobacteria,2YVWE@29|Myxococcales	28221|Deltaproteobacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1280565_6	448385.sce5350	1.243e-99	340.0	28WCZ@1|root,32WPU@2|Bacteria,1NECW@1224|Proteobacteria	1224|Proteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1280565_3	448385.sce0415	7.02e-143	480.0	COG2304@1|root,COG2304@2|Bacteria,1NX8F@1224|Proteobacteria,430QD@68525|delta/epsilon subdivisions,2WVNR@28221|Deltaproteobacteria,2YW4W@29|Myxococcales	28221|Deltaproteobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SHD3_k127_1280565_8	1192034.CAP_5637	5.32e-92	311.0	COG1721@1|root,COG1721@2|Bacteria,1MWPG@1224|Proteobacteria	1224|Proteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	MA20_44650	-	-	-	-	-	-	-	-	-	-	-	DUF58
SHD3_k127_1280565_7	1192034.CAP_5646	7.043e-97	326.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,FecR,LysM,Peptidase_M74
SHD3_k127_1280565_14	448385.sce8934	5.44e-35	146.0	COG1187@1|root,COG5523@1|root,COG1187@2|Bacteria,COG5523@2|Bacteria,1PVR8@1224|Proteobacteria,434AQ@68525|delta/epsilon subdivisions,2WZ03@28221|Deltaproteobacteria,2Z11H@29|Myxococcales	28221|Deltaproteobacteria	J	Uncharacterised protein family (UPF0259)	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1280565_4	448385.sce0423	5.991e-139	490.0	COG1807@1|root,COG1807@2|Bacteria,1R4F0@1224|Proteobacteria	1224|Proteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_1280565_1	1254432.SCE1572_03155	1.879e-159	522.0	COG0455@1|root,COG0484@1|root,COG1426@1|root,COG0455@2|Bacteria,COG0484@2|Bacteria,COG1426@2|Bacteria,1R8IW@1224|Proteobacteria,42R3H@68525|delta/epsilon subdivisions,2WMNY@28221|Deltaproteobacteria,2YUZU@29|Myxococcales	28221|Deltaproteobacteria	D	NUBPL iron-transfer P-loop NTPase	-	-	-	ko:K04562	-	-	-	-	ko00000,ko02035	-	-	-	AAA_31,CbiA,HTH_25,ParA
SHD3_k127_1280565_11	1192034.CAP_2003	1.509e-76	271.0	COG1651@1|root,COG1651@2|Bacteria,1PFNH@1224|Proteobacteria,434F2@68525|delta/epsilon subdivisions,2X8UX@28221|Deltaproteobacteria,2Z0HJ@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SHD3_k127_1280565_10	1254432.SCE1572_43800	4.78e-83	284.0	COG0847@1|root,COG0847@2|Bacteria	2|Bacteria	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease	-	-	2.7.7.7	ko:K02342,ko:K10857	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
SHD3_k127_1280565_16	1192034.CAP_5443	4.743e-20	102.0	COG5549@1|root,COG5549@2|Bacteria,1PBXR@1224|Proteobacteria,43864@68525|delta/epsilon subdivisions,2X0VV@28221|Deltaproteobacteria,2YVXH@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SHD3_k127_1280565_17	1254432.SCE1572_43485	7.328e-20	105.0	COG2755@1|root,COG5297@1|root,COG2755@2|Bacteria,COG5297@2|Bacteria,1PFIY@1224|Proteobacteria,434S6@68525|delta/epsilon subdivisions,2WZ38@28221|Deltaproteobacteria,2Z1QH@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_1280565_20	1121921.KB898706_gene2624	8.753e-09	69.0	COG4124@1|root,COG5297@1|root,COG4124@2|Bacteria,COG5297@2|Bacteria,1Q17Q@1224|Proteobacteria,1RZFV@1236|Gammaproteobacteria,2PMZW@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 26	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM_10,CBM_2,Glyco_hydro_26
SHD3_k127_1280565_18	448385.sce0998	2.795e-15	90.0	COG1506@1|root,COG5297@1|root,COG1506@2|Bacteria,COG5297@2|Bacteria,1R9PN@1224|Proteobacteria	1224|Proteobacteria	E	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1280565_9	448385.sce1043	3.913e-89	312.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUWW@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1280565_0	448385.sce0977	5.06e-208	668.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce0977|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1284519_7	1192034.CAP_6467	2.159e-30	126.0	COG1262@1|root,COG1361@1|root,COG3055@1|root,COG5184@1|root,COG1262@2|Bacteria,COG1361@2|Bacteria,COG3055@2|Bacteria,COG5184@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1284519_9	1038867.AXAY01000005_gene7513	3.035e-25	112.0	2BRF4@1|root,32KE0@2|Bacteria,1Q610@1224|Proteobacteria,2TU9G@28211|Alphaproteobacteria,3JUSE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1284519_0	463191.SSEG_02413	8.842e-176	572.0	COG3669@1|root,COG3669@2|Bacteria,2HUEI@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Fucosidase_C,RicinB_lectin_2
SHD3_k127_1284519_12	78579.XP_003664172.1	1.289e-12	73.0	28IP3@1|root,2QR03@2759|Eukaryota,396BN@33154|Opisthokonta,3NXB9@4751|Fungi,3QRQE@4890|Ascomycota,21746@147550|Sordariomycetes,3U7TI@5139|Sordariales,3HB3W@35718|Chaetomiaceae	4751|Fungi	G	Fungal-type cellulose-binding domain	-	-	3.2.1.155	ko:K18578	-	-	-	-	ko00000,ko01000	-	CBM1,GH74	-	CBM_1
SHD3_k127_1284519_1	1089545.KB913037_gene3625	5.268e-173	569.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,2GJF7@201174|Actinobacteria,4E7JT@85010|Pseudonocardiales	201174|Actinobacteria	G	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,RicinB_lectin_2
SHD3_k127_1284519_10	391612.CY0110_30331	2.369e-16	81.0	COG5450@1|root,COG5450@2|Bacteria,1G9ST@1117|Cyanobacteria,3KK8T@43988|Cyanothece	1117|Cyanobacteria	K	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SHD3_k127_1284519_5	118161.KB235922_gene3690	3.256e-37	147.0	COG1487@1|root,COG1487@2|Bacteria,1G736@1117|Cyanobacteria	1117|Cyanobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_1284519_11	247633.GP2143_02944	2.372e-14	74.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria,1J81D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
SHD3_k127_1284519_15	99598.Cal7507_2330	2.86e-08	63.0	2DY1B@1|root,347KB@2|Bacteria,1GFI5@1117|Cyanobacteria	1117|Cyanobacteria	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
SHD3_k127_1284519_2	1254432.SCE1572_30460	4.696e-75	287.0	COG3568@1|root,COG3568@2|Bacteria,1PG5A@1224|Proteobacteria,43E4I@68525|delta/epsilon subdivisions,2WZPU@28221|Deltaproteobacteria,2Z2HE@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1284519_14	68170.KL590474_gene5772	2.797e-08	67.0	COG4870@1|root,COG4870@2|Bacteria,2I4QS@201174|Actinobacteria,4E2KS@85010|Pseudonocardiales	201174|Actinobacteria	O	Repeat of unknown function (DUF346)	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
SHD3_k127_1284519_3	1192034.CAP_8496	1.011e-55	214.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_8496|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1284519_6	1242864.D187_000099	1.883e-31	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4,Sigma70_r4_2
SHD3_k127_1284519_4	502025.Hoch_6179	5.469e-55	204.0	COG2931@1|root,COG2931@2|Bacteria,1QX6U@1224|Proteobacteria,4347R@68525|delta/epsilon subdivisions,2X2DH@28221|Deltaproteobacteria,2YUFB@29|Myxococcales	28221|Deltaproteobacteria	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Astacin,VCBS
SHD3_k127_1284519_16	1246474.ANBE01000044_gene816	5.673e-08	67.0	COG4447@1|root,COG4447@2|Bacteria,2HEKN@201174|Actinobacteria,4EKEB@85012|Streptosporangiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1284519_8	502025.Hoch_0370	6.719e-27	129.0	COG4447@1|root,COG4447@2|Bacteria,1R42J@1224|Proteobacteria,42WGC@68525|delta/epsilon subdivisions,2WRHI@28221|Deltaproteobacteria,2YVIP@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1284519_17	1121904.ARBP01000001_gene5537	0.000706	49.0	2ECCV@1|root,336B4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SHD3_k127_1284519_13	395493.BegalDRAFT_2446	2.588e-10	62.0	COG2931@1|root,COG5184@1|root,COG2931@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,1SA3X@1236|Gammaproteobacteria	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_1288308_6	448385.sce8630	2.434e-65	228.0	COG1473@1|root,COG1473@2|Bacteria,1MX6N@1224|Proteobacteria,42S5J@68525|delta/epsilon subdivisions,2WNJC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Peptidase dimerisation domain	-	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SHD3_k127_1288308_2	1192034.CAP_3102	3.516e-135	442.0	COG1092@1|root,COG1092@2|Bacteria,1MUGB@1224|Proteobacteria,42M7K@68525|delta/epsilon subdivisions,2WKKM@28221|Deltaproteobacteria,2YUWI@29|Myxococcales	28221|Deltaproteobacteria	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,Methyltransf_25
SHD3_k127_1288308_13	886293.Sinac_2827	2.769e-28	118.0	COG0776@1|root,COG0776@2|Bacteria,2J0XR@203682|Planctomycetes	203682|Planctomycetes	L	Belongs to the bacterial histone-like protein family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
SHD3_k127_1288308_12	1192034.CAP_3099	6.384e-29	124.0	COG0319@1|root,COG0319@2|Bacteria,1MZ67@1224|Proteobacteria,42W3M@68525|delta/epsilon subdivisions,2WRMB@28221|Deltaproteobacteria,2YYJR@29|Myxococcales	28221|Deltaproteobacteria	J	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	Cupin_2,UPF0054
SHD3_k127_1288308_8	1254432.SCE1572_00100	8.029e-57	207.0	COG0561@1|root,COG0561@2|Bacteria,1R4WX@1224|Proteobacteria,42P98@68525|delta/epsilon subdivisions,2WJWW@28221|Deltaproteobacteria,2YVRM@29|Myxococcales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SHD3_k127_1288308_1	1254432.SCE1572_00025	1.156e-144	470.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,42MHH@68525|delta/epsilon subdivisions,2WIMW@28221|Deltaproteobacteria,2YTVG@29|Myxococcales	28221|Deltaproteobacteria	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iAF987.Gmet_0204	Aminotran_3
SHD3_k127_1288308_3	1094980.Mpsy_1079	2.709e-86	297.0	COG0448@1|root,arCOG00912@2157|Archaea,2XTI4@28890|Euryarchaeota,2N975@224756|Methanomicrobia	224756|Methanomicrobia	E	Belongs to the ATCase OTCase family	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SHD3_k127_1288308_0	448385.sce0006	1.022e-182	600.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	-	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,Hydrolase
SHD3_k127_1288308_11	1192034.CAP_6331	2.25e-34	140.0	COG0212@1|root,COG0212@2|Bacteria,1MZG0@1224|Proteobacteria,42U47@68525|delta/epsilon subdivisions,2WQXE@28221|Deltaproteobacteria,2YVV5@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
SHD3_k127_1288308_4	1254432.SCE1572_41055	1.816e-67	238.0	COG1216@1|root,COG1216@2|Bacteria,1QVEM@1224|Proteobacteria,42NYG@68525|delta/epsilon subdivisions,2WIXP@28221|Deltaproteobacteria,2Z1KB@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	DUF2062,Glycos_transf_2
SHD3_k127_1288308_7	448385.sce1670	3.308e-65	237.0	COG2339@1|root,COG2339@2|Bacteria,1PCW8@1224|Proteobacteria,4343U@68525|delta/epsilon subdivisions,2X52Q@28221|Deltaproteobacteria,2Z013@29|Myxococcales	28221|Deltaproteobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SHD3_k127_1296598_13	319225.Plut_1918	4.218e-11	69.0	2C78Q@1|root,331C6@2|Bacteria	2|Bacteria	S	Protein  of unknown function (DUF3018)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3018
SHD3_k127_1296598_8	331678.Cphamn1_0733	1.372e-35	138.0	COG2337@1|root,COG2337@2|Bacteria,1FFDG@1090|Chlorobi	1090|Chlorobi	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SHD3_k127_1296598_12	1268068.PG5_33390	4.459e-12	72.0	COG3344@1|root,COG3344@2|Bacteria,1RD41@1224|Proteobacteria,1SASD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
SHD3_k127_1296598_6	1230476.C207_06597	5.325e-49	180.0	29SS3@1|root,30DY0@2|Bacteria,1NH1Z@1224|Proteobacteria,2URCH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1296598_5	448385.sce0854	1.47e-64	234.0	COG2821@1|root,COG2821@2|Bacteria,1NIC3@1224|Proteobacteria,433CJ@68525|delta/epsilon subdivisions,2WXQG@28221|Deltaproteobacteria,2Z1V4@29|Myxococcales	28221|Deltaproteobacteria	M	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
SHD3_k127_1296598_4	1192034.CAP_5434	4.155e-75	260.0	COG0483@1|root,COG0483@2|Bacteria,1MUQT@1224|Proteobacteria,42R1W@68525|delta/epsilon subdivisions,2WMQ4@28221|Deltaproteobacteria,2YVHS@29|Myxococcales	28221|Deltaproteobacteria	G	Inositol monophosphatase	suhB	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SHD3_k127_1296598_7	352165.HMPREF7215_0448	3.077e-46	171.0	COG3012@1|root,COG3012@2|Bacteria,3TC58@508458|Synergistetes	508458|Synergistetes	U	SEC-C motif	-	-	-	-	-	-	-	-	-	-	-	-	SEC-C
SHD3_k127_1296598_0	448385.sce7631	2.834e-170	563.0	COG0773@1|root,COG0773@2|Bacteria,1MUC5@1224|Proteobacteria,42NMY@68525|delta/epsilon subdivisions,2WJ8S@28221|Deltaproteobacteria,2YU74@29|Myxococcales	28221|Deltaproteobacteria	M	Mur ligase family, catalytic domain	mpl	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SHD3_k127_1296598_1	404589.Anae109_2667	1.202e-105	351.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SHD3_k127_1296598_3	448385.sce3776	1.162e-76	275.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SHD3_k127_1296598_10	502025.Hoch_6453	5.467e-18	95.0	28W5H@1|root,2ZI6A@2|Bacteria,1QBFX@1224|Proteobacteria,435GD@68525|delta/epsilon subdivisions,2WZTW@28221|Deltaproteobacteria,2Z2QX@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF3108)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3108
SHD3_k127_1296598_11	1297742.A176_04856	5.548e-13	78.0	COG5612@1|root,COG5612@2|Bacteria,1PBU8@1224|Proteobacteria,433TF@68525|delta/epsilon subdivisions,2X3E2@28221|Deltaproteobacteria,2YVN2@29|Myxococcales	28221|Deltaproteobacteria	S	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
SHD3_k127_1296598_2	1254432.SCE1572_12475	2.02e-92	308.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42RGE@68525|delta/epsilon subdivisions,2WNF7@28221|Deltaproteobacteria,2YUAH@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_1296598_9	1278073.MYSTI_05878	4.621e-29	123.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,43BZY@68525|delta/epsilon subdivisions,2X39W@28221|Deltaproteobacteria,2YV13@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_1300409_1	207559.Dde_1893	0.0	1164.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,42M8F@68525|delta/epsilon subdivisions,2WIU0@28221|Deltaproteobacteria,2M7WE@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
SHD3_k127_1300409_3	102125.Xen7305DRAFT_00015430	5.165e-90	312.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	CP_0674	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,PTS_EIIA_2
SHD3_k127_1300409_0	697282.Mettu_0545	0.0	1313.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,1RN8P@1236|Gammaproteobacteria,1XEHU@135618|Methylococcales	135618|Methylococcales	G	TIGRFAM alpha-glucan	-	-	-	-	-	-	-	-	-	-	-	-	DUF3417,Phosphorylase
SHD3_k127_1300409_2	1123393.KB891326_gene87	2.832e-282	876.0	COG0033@1|root,COG0033@2|Bacteria,1MU5S@1224|Proteobacteria,2VKCX@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Phosphoglucomutase phosphomannomutase alpha beta alpha domain I	pgm	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SHD3_k127_1309652_2	357808.RoseRS_0421	8.56e-79	271.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_1309652_4	1121396.KB893120_gene3067	1.384e-46	178.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1309652_0	1034769.KB910518_gene2222	5.297e-172	559.0	COG3507@1|root,COG3507@2|Bacteria,1TT53@1239|Firmicutes,4IPIB@91061|Bacilli,26VUU@186822|Paenibacillaceae	91061|Bacilli	M	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SHD3_k127_1309652_1	485913.Krac_4022	3.381e-87	297.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
SHD3_k127_1309652_8	485913.Krac_1423	2.041e-17	94.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
SHD3_k127_1309652_11	555778.Hneap_1519	2.073e-05	48.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,1RM9A@1236|Gammaproteobacteria,1WWP6@135613|Chromatiales	135613|Chromatiales	D	DNA segregation ATPase FtsK SpoIIIE	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SHD3_k127_1309652_3	246197.MXAN_0519	3.253e-67	233.0	COG4636@1|root,COG4636@2|Bacteria,1RCFH@1224|Proteobacteria,43ACW@68525|delta/epsilon subdivisions,2X5SW@28221|Deltaproteobacteria,2YZYB@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_1309652_7	1206720.BAFQ01000298_gene6804	9.074e-19	94.0	COG1484@1|root,COG1484@2|Bacteria,2H714@201174|Actinobacteria,4G3K3@85025|Nocardiaceae	201174|Actinobacteria	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SHD3_k127_1309652_6	448385.sce6213	2.606e-26	112.0	COG1262@1|root,COG1262@2|Bacteria,1NQ5K@1224|Proteobacteria	1224|Proteobacteria	M	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
SHD3_k127_1309652_12	272123.Anacy_1783	0.0001165	54.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,CARDB,FTP,Peptidase_M36,Trypsin,Trypsin_2
SHD3_k127_1309652_10	1254432.SCE1572_51540	6.648e-09	65.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Rhs family	-	-	-	-	-	-	-	-	-	-	-	-	AHH,RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
SHD3_k127_1311395_7	582402.Hbal_1697	5.061e-08	55.0	COG0512@1|root,COG0512@2|Bacteria,1MV5Y@1224|Proteobacteria,2TU3N@28211|Alphaproteobacteria,43XHM@69657|Hyphomonadaceae	28211|Alphaproteobacteria	EH	COG0512 Anthranilate para-aminobenzoate synthases component II	trpG	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SHD3_k127_1311395_5	448385.sce4289	1.725e-66	236.0	COG2267@1|root,COG2267@2|Bacteria,1QX85@1224|Proteobacteria,42W1M@68525|delta/epsilon subdivisions,2WR6V@28221|Deltaproteobacteria,2YUZN@29|Myxococcales	28221|Deltaproteobacteria	I	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SHD3_k127_1311395_2	448385.sce4286	2.442e-84	296.0	COG1253@1|root,COG1253@2|Bacteria,1MV3P@1224|Proteobacteria,42QX1@68525|delta/epsilon subdivisions,2WMNH@28221|Deltaproteobacteria,2Z2XP@29|Myxococcales	28221|Deltaproteobacteria	S	Transporter associated domain	corC	-	-	ko:K06189	-	-	-	-	ko00000,ko02000	9.A.40.1.2	-	-	CBS,CorC_HlyC,DUF21
SHD3_k127_1311395_4	1254432.SCE1572_25900	1.977e-72	259.0	COG0130@1|root,COG0130@2|Bacteria,1MV0N@1224|Proteobacteria,42MU5@68525|delta/epsilon subdivisions,2WKWY@28221|Deltaproteobacteria,2YVB2@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
SHD3_k127_1311395_0	1254432.SCE1572_25895	6.823e-106	358.0	COG0204@1|root,COG0204@2|Bacteria,1N01J@1224|Proteobacteria,42UM7@68525|delta/epsilon subdivisions,2WQN9@28221|Deltaproteobacteria,2Z3CW@29|Myxococcales	28221|Deltaproteobacteria	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SHD3_k127_1311395_1	1254432.SCE1572_25890	1.254e-104	352.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42UM2@68525|delta/epsilon subdivisions,2WR61@28221|Deltaproteobacteria,2YVAU@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SHD3_k127_1311395_3	502025.Hoch_5887	7.284e-74	265.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
SHD3_k127_1317356_1	1173020.Cha6605_1515	5.496e-76	266.0	COG0338@1|root,COG0338@2|Bacteria,1G2GJ@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SHD3_k127_1317356_2	1283300.ATXB01000001_gene1241	3.143e-57	221.0	COG0297@1|root,COG3330@1|root,COG0297@2|Bacteria,COG3330@2|Bacteria,1R6U0@1224|Proteobacteria	1224|Proteobacteria	G	Starch synthase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
SHD3_k127_1317356_0	1121430.JMLG01000005_gene758	4.108e-124	411.0	COG1543@1|root,COG1543@2|Bacteria,1TPFX@1239|Firmicutes,248UF@186801|Clostridia,25ZYE@186807|Peptococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 57 family	-	-	2.4.1.18	ko:K16149	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000	-	GH57	-	DUF1957,Glyco_hydro_57
SHD3_k127_1322573_3	868131.MSWAN_0160	2.688e-26	121.0	COG2006@1|root,arCOG02447@2157|Archaea,2Y2ES@28890|Euryarchaeota	28890|Euryarchaeota	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_1322573_0	743299.Acife_3019	2.548e-91	318.0	COG1232@1|root,COG1232@2|Bacteria,1P80H@1224|Proteobacteria,1S0R5@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SHD3_k127_1322573_1	156889.Mmc1_1139	6.124e-67	236.0	COG0500@1|root,COG2226@2|Bacteria,1RFGA@1224|Proteobacteria,2URNK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SHD3_k127_1322573_4	706587.Desti_1501	5.806e-24	118.0	COG1807@1|root,COG1807@2|Bacteria,1Q6N9@1224|Proteobacteria,433F2@68525|delta/epsilon subdivisions,2WXMF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_1322573_2	666681.M301_2258	2.871e-50	194.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2VHJ2@28216|Betaproteobacteria,2KMYM@206350|Nitrosomonadales	206350|Nitrosomonadales	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SHD3_k127_133783_3	941449.dsx2_0979	2.23e-20	98.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42TBU@68525|delta/epsilon subdivisions,2WP21@28221|Deltaproteobacteria,2MGK5@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SHD3_k127_133783_0	1122919.KB905591_gene4016	1.078e-213	674.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,4HCUX@91061|Bacilli,26RY2@186822|Paenibacillaceae	91061|Bacilli	G	alpha-N-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
SHD3_k127_133783_1	1254432.SCE1572_49925	1.508e-147	493.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,4347K@68525|delta/epsilon subdivisions,2X42E@28221|Deltaproteobacteria,2YY2K@29|Myxococcales	28221|Deltaproteobacteria	OU	Peptidase family S49	-	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SHD3_k127_133783_2	1192034.CAP_8291	5.504e-51	203.0	COG0457@1|root,COG0457@2|Bacteria,1QQ0R@1224|Proteobacteria,433U8@68525|delta/epsilon subdivisions,2X3GZ@28221|Deltaproteobacteria,2YW20@29|Myxococcales	28221|Deltaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,zinc_ribbon_4
SHD3_k127_1359548_0	251221.35211841	3.108e-108	379.0	COG1404@1|root,COG1404@2|Bacteria,1G8UV@1117|Cyanobacteria	1117|Cyanobacteria	O	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,VCBS
SHD3_k127_1359548_3	1089545.KB913037_gene1880	7.904e-75	269.0	COG4124@1|root,COG4124@2|Bacteria,2GJ4D@201174|Actinobacteria,4E9T8@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 26	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26,Ricin_B_lectin
SHD3_k127_1359548_8	2002.JOEQ01000029_gene8282	0.0003823	50.0	COG1595@1|root,COG1595@2|Bacteria,2GP81@201174|Actinobacteria,4EJGD@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	sigE	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_1359548_5	391625.PPSIR1_38806	2.489e-11	76.0	2AN2E@1|root,31CZZ@2|Bacteria,1QA0W@1224|Proteobacteria,434RF@68525|delta/epsilon subdivisions,2WZ2M@28221|Deltaproteobacteria,2Z16X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11
SHD3_k127_1359548_2	1254432.SCE1572_20375	1.366e-103	350.0	2FIE8@1|root,34A6F@2|Bacteria,1P3KN@1224|Proteobacteria,431Y1@68525|delta/epsilon subdivisions,2WWQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4423
SHD3_k127_1359548_1	1254432.SCE1572_46825	3.687e-107	361.0	COG5297@1|root,COG5297@2|Bacteria,1QZI4@1224|Proteobacteria,43CJ7@68525|delta/epsilon subdivisions,2X7TJ@28221|Deltaproteobacteria,2YXMV@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 6	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_3,Glyco_hydro_6,fn3
SHD3_k127_1359548_7	675815.VOA_001336	1.684e-06	57.0	COG2199@1|root,COG2199@2|Bacteria,1QXRF@1224|Proteobacteria,1T3HM@1236|Gammaproteobacteria,1Y35A@135623|Vibrionales	135623|Vibrionales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SHD3_k127_1370422_3	448385.sce8989	3.787e-60	220.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_1370422_2	335543.Sfum_2911	4.343e-71	251.0	28NNB@1|root,2ZBNN@2|Bacteria,1N34G@1224|Proteobacteria,42YIA@68525|delta/epsilon subdivisions,2WURD@28221|Deltaproteobacteria,2MR7U@213462|Syntrophobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1370422_1	1313172.YM304_11060	1.405e-91	311.0	2DB7V@1|root,2Z7NX@2|Bacteria,2I9CJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1370422_0	1192034.CAP_0884	9.916e-141	466.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SHD3_k127_1384875_0	9305.ENSSHAP00000009509	0.0005343	53.0	KOG1218@1|root,KOG2217@1|root,KOG1218@2759|Eukaryota,KOG2217@2759|Eukaryota,38CGW@33154|Opisthokonta,3BEXX@33208|Metazoa,3CV8Y@33213|Bilateria,47Z98@7711|Chordata,492GD@7742|Vertebrata,3J4SZ@40674|Mammalia,4JY66@9263|Metatheria	33208|Metazoa	T	Stabilin 1	STAB1	GO:0003674,GO:0003824,GO:0005041,GO:0005044,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006810,GO:0006897,GO:0006898,GO:0006950,GO:0006952,GO:0007154,GO:0007155,GO:0007267,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0012506,GO:0015035,GO:0015036,GO:0016020,GO:0016021,GO:0016192,GO:0016491,GO:0016525,GO:0016667,GO:0022603,GO:0022610,GO:0023052,GO:0030139,GO:0030169,GO:0030228,GO:0030659,GO:0030666,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0038024,GO:0042742,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045765,GO:0048519,GO:0050789,GO:0050793,GO:0050896,GO:0051093,GO:0051179,GO:0051234,GO:0051239,GO:0051241,GO:0051704,GO:0051707,GO:0055114,GO:0065007,GO:0071813,GO:0071814,GO:0071944,GO:0097708,GO:0098542,GO:0098588,GO:0098657,GO:0098805,GO:1901342,GO:1901343,GO:2000026,GO:2000181	-	ko:K19013,ko:K19020	-	-	-	-	ko00000,ko00536	-	-	-	EGF_3,Fasciclin,Xlink
SHD3_k127_1397855_4	153721.MYP_458	2.478e-61	227.0	COG2273@1|root,COG2730@1|root,COG4447@1|root,COG2273@2|Bacteria,COG2730@2|Bacteria,COG4447@2|Bacteria,4NIBG@976|Bacteroidetes,47P3X@768503|Cytophagia	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
SHD3_k127_1397855_9	1148.1652890	2.297e-07	63.0	2EYA9@1|root,33RIQ@2|Bacteria,1GCQY@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1397855_1	1254432.SCE1572_15570	8.936e-135	451.0	COG0664@1|root,COG3264@1|root,COG0664@2|Bacteria,COG3264@2|Bacteria,1QX62@1224|Proteobacteria,42S57@68525|delta/epsilon subdivisions,2WNY0@28221|Deltaproteobacteria,2YVPP@29|Myxococcales	28221|Deltaproteobacteria	MT	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,cNMP_binding
SHD3_k127_1397855_5	404589.Anae109_0987	4.907e-30	129.0	COG1371@1|root,COG1371@2|Bacteria	2|Bacteria	J	PFAM Archease protein family (DUF101 UPF0211)	-	-	2.7.7.72	ko:K00974	ko03013,map03013	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Archease
SHD3_k127_1397855_0	290397.Adeh_0946	1.57e-197	626.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the RtcB family	rtcB	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SHD3_k127_1397855_10	1192034.CAP_3816	1.308e-06	57.0	COG2165@1|root,COG2165@2|Bacteria	2|Bacteria	NU	general secretion pathway protein	-	-	-	ko:K02456,ko:K02650,ko:K10926,ko:K12285	ko02020,ko03070,ko05111,map02020,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.15,3.A.15.2	-	-	N_methyl,Pilin_GH
SHD3_k127_1397855_2	1254432.SCE1572_31735	1.69e-118	411.0	COG1609@1|root,COG2208@1|root,COG1609@2|Bacteria,COG2208@2|Bacteria,1RHRV@1224|Proteobacteria,43ARR@68525|delta/epsilon subdivisions,2X65U@28221|Deltaproteobacteria,2Z0U1@29|Myxococcales	28221|Deltaproteobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3,SpoIIE
SHD3_k127_1397855_3	525897.Dbac_2084	4.147e-64	229.0	COG2360@1|root,COG2360@2|Bacteria,1R9W8@1224|Proteobacteria,42QRC@68525|delta/epsilon subdivisions,2WMP7@28221|Deltaproteobacteria,2M9ZR@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
SHD3_k127_140150_5	448385.sce4949	4.871e-99	347.0	COG0402@1|root,COG1506@1|root,COG5184@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_140150_8	1121406.JAEX01000001_gene433	4.233e-63	228.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WNYM@28221|Deltaproteobacteria,2MG63@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SHD3_k127_140150_11	1254432.SCE1572_50700	1.503e-28	122.0	COG5552@1|root,COG5552@2|Bacteria,1MZBV@1224|Proteobacteria,4315I@68525|delta/epsilon subdivisions,2WWPX@28221|Deltaproteobacteria,2YVPZ@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
SHD3_k127_140150_12	748449.Halha_0085	1.082e-24	115.0	COG0265@1|root,COG0265@2|Bacteria,1TRQS@1239|Firmicutes,24E3C@186801|Clostridia,3WBFM@53433|Halanaerobiales	186801|Clostridia	O	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S7,Trypsin
SHD3_k127_140150_1	246197.MXAN_1269	3.704e-131	450.0	COG1752@1|root,COG1752@2|Bacteria,1Q9RI@1224|Proteobacteria,434JD@68525|delta/epsilon subdivisions,2X8X1@28221|Deltaproteobacteria,2Z0T6@29|Myxococcales	28221|Deltaproteobacteria	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SHD3_k127_140150_4	439235.Dalk_1602	3.182e-109	382.0	COG0642@1|root,COG0834@1|root,COG0834@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43BSB@68525|delta/epsilon subdivisions,2X735@28221|Deltaproteobacteria,2MPRY@213118|Desulfobacterales	28221|Deltaproteobacteria	T	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SBP_bac_3
SHD3_k127_140150_10	1132855.KB913035_gene1364	2.371e-34	145.0	COG0784@1|root,COG0784@2|Bacteria,1QU3I@1224|Proteobacteria,2WGTG@28216|Betaproteobacteria,2KNXS@206350|Nitrosomonadales	206350|Nitrosomonadales	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_140150_3	1547437.LL06_09785	2.844e-126	422.0	COG2195@1|root,COG2195@2|Bacteria,1MV7D@1224|Proteobacteria,2TRNW@28211|Alphaproteobacteria,43MJU@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
SHD3_k127_140150_9	1540221.JQNI01000004_gene79	1.295e-42	165.0	COG4291@1|root,COG4291@2|Bacteria	2|Bacteria	C	membrane	MA20_23190	-	-	-	-	-	-	-	-	-	-	-	DUF1345
SHD3_k127_140150_2	1089545.KB913037_gene9101	7.308e-130	432.0	COG3669@1|root,COG3669@2|Bacteria,2I650@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C,RicinB_lectin_2
SHD3_k127_140150_0	1120949.KB903297_gene5459	1.108e-184	587.0	COG1506@1|root,COG5297@1|root,COG1506@2|Bacteria,COG5297@2|Bacteria,2GNJM@201174|Actinobacteria,4DBDW@85008|Micromonosporales	201174|Actinobacteria	EG	CBD_II	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SHD3_k127_140150_13	1242864.D187_009164	6.003e-06	59.0	COG4305@1|root,COG4305@2|Bacteria,1MYW4@1224|Proteobacteria	1224|Proteobacteria	G	Lytic transglycolase	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	CBM_2,Cellulase,DPBB_1,Pollen_allerg_1
SHD3_k127_140150_7	1499967.BAYZ01000103_gene3758	4.101e-83	299.0	COG0457@1|root,COG0457@2|Bacteria	1499967.BAYZ01000103_gene3758|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_140150_6	1229780.BN381_80256	7.504e-85	300.0	COG1404@1|root,COG5184@1|root,COG1404@2|Bacteria,COG5184@2|Bacteria,2IG31@201174|Actinobacteria	201174|Actinobacteria	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2,SLH
SHD3_k127_1402412_9	365046.Rta_09290	2.002e-18	89.0	COG0628@1|root,COG0628@2|Bacteria,1MVX7@1224|Proteobacteria,2VIIX@28216|Betaproteobacteria,4AAH8@80864|Comamonadaceae	28216|Betaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SHD3_k127_1402412_5	448385.sce4353	8.684e-51	190.0	COG0363@1|root,COG0363@2|Bacteria,1R5K6@1224|Proteobacteria,42UV6@68525|delta/epsilon subdivisions,2WP1R@28221|Deltaproteobacteria,2YVX1@29|Myxococcales	28221|Deltaproteobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	pgl	-	3.1.1.31	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
SHD3_k127_1402412_2	575540.Isop_1743	3.455e-66	241.0	COG1215@1|root,COG1215@2|Bacteria,2IZJX@203682|Planctomycetes	203682|Planctomycetes	M	TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
SHD3_k127_1402412_4	1254432.SCE1572_22005	1.25e-57	208.0	COG0568@1|root,COG0568@2|Bacteria,1PBSF@1224|Proteobacteria,433T8@68525|delta/epsilon subdivisions,2X9VU@28221|Deltaproteobacteria,2YVGG@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70, region 4	asgB	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
SHD3_k127_1402412_10	797299.HALLA_14510	4.753e-13	78.0	COG1011@1|root,arCOG02291@2157|Archaea,2XW3Z@28890|Euryarchaeota,23SFY@183963|Halobacteria	183963|Halobacteria	S	hydrolase (HAD superfamily)	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
SHD3_k127_1402412_0	1408473.JHXO01000005_gene1751	2.124e-116	392.0	COG1180@1|root,COG1180@2|Bacteria,4NJ18@976|Bacteroidetes,2FQZB@200643|Bacteroidia	976|Bacteroidetes	O	radical SAM domain protein	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SHD3_k127_1402412_1	439235.Dalk_3070	8.465e-72	271.0	COG4262@1|root,COG4262@2|Bacteria,1QTYC@1224|Proteobacteria,42Q43@68525|delta/epsilon subdivisions,2WKQF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_1402412_6	439235.Dalk_3956	2.703e-45	174.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,42PPP@68525|delta/epsilon subdivisions,2WJ0H@28221|Deltaproteobacteria,2MPVY@213118|Desulfobacterales	28221|Deltaproteobacteria	S	AMMECR1	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
SHD3_k127_1402412_3	215803.DB30_3716	1.683e-62	226.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42PPP@68525|delta/epsilon subdivisions,2WJ0H@28221|Deltaproteobacteria,2YVVJ@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
SHD3_k127_1402412_7	448385.sce3942	9.837e-34	141.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1406797_8	404589.Anae109_3678	3.303e-14	75.0	COG4372@1|root,COG4372@2|Bacteria,1MUCX@1224|Proteobacteria,43CJZ@68525|delta/epsilon subdivisions,2X7UE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	IS66 C-terminal element	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C
SHD3_k127_1406797_3	1403819.BATR01000081_gene2323	7.222e-24	113.0	COG3115@1|root,COG3115@2|Bacteria	2|Bacteria	D	cell septum assembly	zipA	-	-	ko:K03528	-	-	-	-	ko00000,ko03036	-	-	-	SPOR,ZipA_C
SHD3_k127_1406797_7	555779.Dthio_PD2840	1.087e-14	75.0	COG2929@1|root,COG2929@2|Bacteria,1N6QP@1224|Proteobacteria,42VMA@68525|delta/epsilon subdivisions,2WS3K@28221|Deltaproteobacteria,2ME5A@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	BrnT_toxin
SHD3_k127_1406797_10	378806.STAUR_2950	3.287e-10	68.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42P3V@68525|delta/epsilon subdivisions,2WKWV@28221|Deltaproteobacteria,2YTVV@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SHD3_k127_1406797_0	1254432.SCE1572_15395	1.82e-75	257.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42P3V@68525|delta/epsilon subdivisions,2WKWV@28221|Deltaproteobacteria,2YTVV@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SHD3_k127_1406797_6	1254432.SCE1572_27170	2.661e-16	83.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SHD3_k127_1406797_2	1144275.COCOR_03665	6.892e-29	136.0	COG5492@1|root,COG5492@2|Bacteria,1PBEQ@1224|Proteobacteria	1224|Proteobacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1406797_9	243277.VC_A0027	9.003e-11	76.0	COG3325@1|root,COG3979@1|root,COG3325@2|Bacteria,COG3979@2|Bacteria,1MWAR@1224|Proteobacteria,1RPNS@1236|Gammaproteobacteria,1XT0T@135623|Vibrionales	135623|Vibrionales	G	COG3325 Chitinase	chiA	-	3.2.1.14	ko:K01183	ko00520,ko01100,map00520,map01100	-	R01206,R02334	RC00467	ko00000,ko00001,ko01000	-	GH18	-	CBM_5_12,ChitinaseA_N,Glyco_hydro_18,REJ
SHD3_k127_1406797_4	1192034.CAP_7394	1.419e-22	102.0	COG0338@1|root,COG0338@2|Bacteria,1P85S@1224|Proteobacteria,42RAF@68525|delta/epsilon subdivisions,2WN7G@28221|Deltaproteobacteria,2Z09C@29|Myxococcales	28221|Deltaproteobacteria	H	Site-specific DNA-methyltransferase (Adenine-specific)	-	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
SHD3_k127_1406797_1	1192034.CAP_6604	7.929e-38	149.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_1406797_13	225117.XP_009350379.1	3.34e-05	56.0	KOG1217@1|root,KOG1217@2759|Eukaryota	2759|Eukaryota	O	calcium ion binding	dp	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA
SHD3_k127_1406797_5	314278.NB231_09623	8.588e-20	92.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1T3U5@1236|Gammaproteobacteria,1X1MF@135613|Chromatiales	135613|Chromatiales	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
SHD3_k127_1412494_2	1463934.JOCF01000017_gene4038	6.96e-07	55.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 26 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SHD3_k127_1412494_1	448385.sce0921	2.237e-51	211.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1PEJP@1224|Proteobacteria,433ZI@68525|delta/epsilon subdivisions,2X487@28221|Deltaproteobacteria,2YYGN@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase,TIR_2
SHD3_k127_1412494_0	448385.sce2921	0.0	1210.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_7,TPR_8
SHD3_k127_1438966_6	68260.JOAY01000002_gene5126	2.103e-06	59.0	COG3291@1|root,COG5297@1|root,COG3291@2|Bacteria,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 12 (cellulase H) family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_12,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_1438966_5	1144275.COCOR_01948	8.065e-07	61.0	29RMJ@1|root,30CQT@2|Bacteria,1QTPA@1224|Proteobacteria,4380Z@68525|delta/epsilon subdivisions,2X3B0@28221|Deltaproteobacteria,2YV6U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1438966_0	1385935.N836_20050	5.538e-132	437.0	COG1233@1|root,COG1233@2|Bacteria,1GCDS@1117|Cyanobacteria	1117|Cyanobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
SHD3_k127_1438966_1	1254432.SCE1572_02885	5.751e-118	404.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2X3SJ@28221|Deltaproteobacteria,2YX0A@29|Myxococcales	28221|Deltaproteobacteria	OU	Signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SHD3_k127_1438966_3	1192034.CAP_3241	2.293e-33	149.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
SHD3_k127_1438966_2	247490.KSU1_C0355	4.331e-116	389.0	COG1322@1|root,COG1322@2|Bacteria,2J2TY@203682|Planctomycetes	203682|Planctomycetes	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
SHD3_k127_1438966_4	1123508.JH636453_gene5807	6.829e-20	94.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Calx-beta,DUF4347,HemolysinCabind,VCBS
SHD3_k127_144006_1	246197.MXAN_0519	1.958e-72	248.0	COG4636@1|root,COG4636@2|Bacteria,1RCFH@1224|Proteobacteria,43ACW@68525|delta/epsilon subdivisions,2X5SW@28221|Deltaproteobacteria,2YZYB@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_144006_0	452637.Oter_4282	1.267e-159	530.0	COG0457@1|root,COG0457@2|Bacteria,46V1N@74201|Verrucomicrobia,3KA0R@414999|Opitutae	74201|Verrucomicrobia	M	SMART Tetratricopeptide domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2,TPR_11,TPR_16,TPR_2,TPR_8
SHD3_k127_144006_3	448385.sce0136	2.988e-11	76.0	COG3391@1|root,COG3391@2|Bacteria,1Q2JN@1224|Proteobacteria,4386H@68525|delta/epsilon subdivisions,2X9ZH@28221|Deltaproteobacteria,2YVZH@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,Stig1
SHD3_k127_144006_2	394503.Ccel_0881	1.167e-19	98.0	COG3534@1|root,COG3534@2|Bacteria,1V9Q0@1239|Firmicutes,24JJ3@186801|Clostridia,36QUE@31979|Clostridiaceae	186801|Clostridia	G	Peptidase M60, enhancin and enhancin-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M60
SHD3_k127_1443600_3	215803.DB30_5088	3.307e-83	282.0	COG4191@1|root,COG4191@2|Bacteria,1R95R@1224|Proteobacteria,42PEG@68525|delta/epsilon subdivisions,2WM8J@28221|Deltaproteobacteria,2YU43@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_1443600_2	378806.STAUR_6001	1.732e-118	396.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,4393J@68525|delta/epsilon subdivisions,2X49H@28221|Deltaproteobacteria,2YYJE@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_1443600_4	1144275.COCOR_01048	2.083e-48	194.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02668,ko:K07708	ko02020,map02020	M00497,M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg,SBP_bac_3
SHD3_k127_1443600_1	1232410.KI421426_gene1375	4.142e-123	406.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,42NYZ@68525|delta/epsilon subdivisions,2WK9U@28221|Deltaproteobacteria,43TPP@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,MannoseP_isomer
SHD3_k127_1443600_5	1121127.JAFA01000039_gene3344	4.686e-09	68.0	COG0477@1|root,COG0477@2|Bacteria,1MXBV@1224|Proteobacteria,2VMP5@28216|Betaproteobacteria,1K0MF@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	transporter	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	Sugar_tr
SHD3_k127_1443600_6	1449353.JQMQ01000005_gene4126	1.387e-05	57.0	COG2271@1|root,COG2271@2|Bacteria,2I32P@201174|Actinobacteria	201174|Actinobacteria	G	Major facilitator Superfamily	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,MFS_4,Sugar_tr
SHD3_k127_1443600_0	1242864.D187_000320	0.0	1024.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YYYT@29|Myxococcales	28221|Deltaproteobacteria	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
SHD3_k127_144592_2	1123400.KB904788_gene199	9.526e-28	121.0	COG1994@1|root,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	ko:K16922	-	-	-	-	ko00000,ko01002	-	-	-	Peptidase_M50
SHD3_k127_144592_1	593750.Metfor_0262	1.837e-30	126.0	COG1533@1|root,arCOG01290@2157|Archaea,2Y1RJ@28890|Euryarchaeota,2NAHF@224756|Methanomicrobia	224756|Methanomicrobia	L	Pfam:Gp37_Gp68	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
SHD3_k127_144592_0	1144307.PMI04_00899	3.078e-48	184.0	COG2253@1|root,COG2253@2|Bacteria,1R66E@1224|Proteobacteria	1224|Proteobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	ko:K09144	-	-	-	-	ko00000	-	-	-	AbiEii,WYL
SHD3_k127_144592_3	1227484.C471_09630	1.111e-25	117.0	COG5340@1|root,arCOG04793@2157|Archaea,2XVVB@28890|Euryarchaeota,23UHQ@183963|Halobacteria	183963|Halobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_1,AbiEi_4
SHD3_k127_1447150_4	269799.Gmet_2888	4.257e-63	237.0	COG2244@1|root,COG2244@2|Bacteria,1RHFX@1224|Proteobacteria,42TXE@68525|delta/epsilon subdivisions,2WSBE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Polysaccharide biosynthesis protein	-	-	-	ko:K03328	-	-	-	-	ko00000	2.A.66.2	-	-	Polysacc_synt_3
SHD3_k127_1447150_6	368407.Memar_0189	1.035e-44	177.0	COG1216@1|root,arCOG01383@2157|Archaea,2XW51@28890|Euryarchaeota,2N9HF@224756|Methanomicrobia	224756|Methanomicrobia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
SHD3_k127_1447150_7	1144275.COCOR_05839	2.487e-16	92.0	2DS2B@1|root,33E7G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1447150_2	111781.Lepto7376_0538	8.074e-97	321.0	COG3510@1|root,COG3510@2|Bacteria	2|Bacteria	V	cephalosporin hydroxylase	-	-	-	-	-	-	-	-	-	-	-	-	CmcI,Methyltransf_24
SHD3_k127_1447150_1	1278073.MYSTI_05065	3.29e-125	407.0	COG1209@1|root,COG1209@2|Bacteria,1MU0X@1224|Proteobacteria,42MTN@68525|delta/epsilon subdivisions,2WJAI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rmlA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SHD3_k127_1447150_5	1444711.CCJF01000005_gene270	5.319e-63	226.0	COG1898@1|root,COG1898@2|Bacteria,2JG3J@204428|Chlamydiae	204428|Chlamydiae	M	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SHD3_k127_1447150_3	1444711.CCJF01000005_gene269	6.903e-72	259.0	COG1091@1|root,COG1091@2|Bacteria,2JG0H@204428|Chlamydiae	204428|Chlamydiae	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
SHD3_k127_1447150_0	1444711.CCJF01000005_gene268	1.684e-146	477.0	COG1088@1|root,COG1088@2|Bacteria,2JGKV@204428|Chlamydiae	204428|Chlamydiae	M	Male sterility protein	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
SHD3_k127_1447150_9	477641.MODMU_5551	6.317e-05	55.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_1447150_8	448385.sce7744	2.081e-11	75.0	COG3266@1|root,COG3266@2|Bacteria,1QA9E@1224|Proteobacteria,434X4@68525|delta/epsilon subdivisions,2WZ81@28221|Deltaproteobacteria,2Z1J2@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1454529_1	290397.Adeh_2902	1.889e-192	608.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SHD3_k127_1454529_4	706587.Desti_2066	3.31e-43	177.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria,4322Q@68525|delta/epsilon subdivisions,2WWF0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1454529_0	1125863.JAFN01000001_gene929	1.953e-204	657.0	COG0272@1|root,COG0272@2|Bacteria,1MV3R@1224|Proteobacteria,42MC5@68525|delta/epsilon subdivisions,2WIT5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
SHD3_k127_1454529_3	661478.OP10G_2217	5.342e-47	186.0	COG3488@1|root,COG3488@2|Bacteria	2|Bacteria	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
SHD3_k127_1454529_5	1123377.AUIV01000005_gene1705	0.0001802	53.0	2AF52@1|root,3153T@2|Bacteria,1PV37@1224|Proteobacteria,1RU47@1236|Gammaproteobacteria,1X7RC@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1454529_2	1254432.SCE1572_32030	1.711e-55	208.0	COG0457@1|root,COG0457@2|Bacteria,1Q9KT@1224|Proteobacteria,43DTC@68525|delta/epsilon subdivisions,2WYTS@28221|Deltaproteobacteria,2Z0KP@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1464457_24	760011.Spico_0734	0.0005916	52.0	COG0477@1|root,COG2814@2|Bacteria,2JAP5@203691|Spirochaetes	203691|Spirochaetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08153,ko:K19576	-	M00717	-	-	ko00000,ko00002,ko02000	2.A.1.2.10,2.A.1.2.8	-	-	MFS_1
SHD3_k127_1464457_14	448385.sce3810	2.987e-58	207.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,2YVE0@29|Myxococcales	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SHD3_k127_1464457_20	305700.B447_07012	1.869e-12	69.0	COG2608@1|root,COG2608@2|Bacteria,1NGBD@1224|Proteobacteria,2VXV9@28216|Betaproteobacteria,2KXCB@206389|Rhodocyclales	206389|Rhodocyclales	C	Heavy metal transport detoxification protein	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
SHD3_k127_1464457_11	448385.sce1768	1.657e-70	265.0	2A4SI@1|root,30TDY@2|Bacteria,1PD6V@1224|Proteobacteria,435EQ@68525|delta/epsilon subdivisions,2X98Q@28221|Deltaproteobacteria,2Z2N2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1464457_4	1254432.SCE1572_46825	4.466e-113	379.0	COG5297@1|root,COG5297@2|Bacteria,1QZI4@1224|Proteobacteria,43CJ7@68525|delta/epsilon subdivisions,2X7TJ@28221|Deltaproteobacteria,2YXMV@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 6	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_3,Glyco_hydro_6,fn3
SHD3_k127_1464457_12	448385.sce4032	2.722e-67	246.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_1464457_3	448385.sce4033	3.869e-114	393.0	2AJ10@1|root,319J4@2|Bacteria,1Q2X4@1224|Proteobacteria,438K5@68525|delta/epsilon subdivisions,2X3UQ@28221|Deltaproteobacteria,2YX5Z@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1464457_23	64363.EME47888	9.318e-05	54.0	COG4305@1|root,2S9P9@2759|Eukaryota,3A0PQ@33154|Opisthokonta,3NV2K@4751|Fungi,3QS06@4890|Ascomycota,201E2@147541|Dothideomycetes,3MI2R@451867|Dothideomycetidae	4751|Fungi	G	Carbohydrate-binding module family 63 protein	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	DPBB_1,Pollen_allerg_1
SHD3_k127_1464457_5	448385.sce0414	1.122e-112	376.0	COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2YU2N@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
SHD3_k127_1464457_9	448385.sce0835	6.472e-101	339.0	COG0414@1|root,COG0414@2|Bacteria,1MV1S@1224|Proteobacteria,42N3J@68525|delta/epsilon subdivisions,2WJ19@28221|Deltaproteobacteria,2YUVT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
SHD3_k127_1464457_13	448385.sce0834	4.5e-60	217.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WN3N@28221|Deltaproteobacteria,2YVHP@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SHD3_k127_1464457_17	391625.PPSIR1_41674	4.059e-39	159.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria,2Z2QM@29|Myxococcales	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SHD3_k127_1464457_16	391625.PPSIR1_41674	1.755e-39	160.0	COG5295@1|root,COG5295@2|Bacteria,1NI1M@1224|Proteobacteria,42ZTF@68525|delta/epsilon subdivisions,2WV01@28221|Deltaproteobacteria,2Z2QM@29|Myxococcales	28221|Deltaproteobacteria	UW	Chaperone of endosialidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S74,YadA_head
SHD3_k127_1464457_18	1254432.SCE1572_09715	1.09e-28	124.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_1464457_8	1163409.UUA_15878	9.622e-103	353.0	COG1524@1|root,COG1524@2|Bacteria,1N5SF@1224|Proteobacteria,1RS7W@1236|Gammaproteobacteria,1X350@135614|Xanthomonadales	1224|Proteobacteria	S	proteins of the AP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
SHD3_k127_1464457_10	1254432.SCE1572_08670	7.143e-81	289.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YV97@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SHD3_k127_1464457_15	658187.LDG_8972	3.23e-58	211.0	28M8G@1|root,2ZAMM@2|Bacteria,1MVBT@1224|Proteobacteria,1RMAM@1236|Gammaproteobacteria,1JE74@118969|Legionellales	118969|Legionellales	S	RES	-	-	-	-	-	-	-	-	-	-	-	-	RES
SHD3_k127_1464457_2	338963.Pcar_1629	1.771e-181	582.0	COG0486@1|root,COG0486@2|Bacteria,1PM94@1224|Proteobacteria,42MYX@68525|delta/epsilon subdivisions,2WJE4@28221|Deltaproteobacteria,43TB1@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Ferrous iron transport protein B	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
SHD3_k127_1464457_1	338963.Pcar_1630	1.733e-185	590.0	COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,42MFS@68525|delta/epsilon subdivisions,2WJPR@28221|Deltaproteobacteria,43U0K@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Fumarase C C-terminus	-	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
SHD3_k127_1464457_0	338963.Pcar_1631	9.316e-193	614.0	COG0502@1|root,COG0502@2|Bacteria,1MXK0@1224|Proteobacteria,42Q6J@68525|delta/epsilon subdivisions,2WKXA@28221|Deltaproteobacteria,43TBD@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
SHD3_k127_1464457_6	443143.GM18_1847	3.848e-111	368.0	COG0502@1|root,COG0502@2|Bacteria,1R8GT@1224|Proteobacteria,42QNT@68525|delta/epsilon subdivisions,2WN06@28221|Deltaproteobacteria,43T1U@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
SHD3_k127_1489682_0	1492737.FEM08_33150	4.6e-228	727.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia,2P0E5@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SHD3_k127_1489682_1	1492737.FEM08_33150	1.028e-220	711.0	COG3250@1|root,COG3250@2|Bacteria,4NEWN@976|Bacteroidetes,1HXYF@117743|Flavobacteriia,2P0E5@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SHD3_k127_1489682_3	1396141.BATP01000022_gene395	2.631e-76	276.0	COG1621@1|root,COG2382@1|root,COG1621@2|Bacteria,COG2382@2|Bacteria,46U0H@74201|Verrucomicrobia,2IVDH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SHD3_k127_1489682_2	3218.PP1S55_131V6.1	7.201e-96	332.0	COG3669@1|root,KOG3340@2759|Eukaryota,37NEY@33090|Viridiplantae,3GGSX@35493|Streptophyta	35493|Streptophyta	G	Alpha-l-fucosidase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004560,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0006516,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009100,GO:0009987,GO:0015928,GO:0016787,GO:0016798,GO:0019538,GO:0030163,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
SHD3_k127_1490544_1	1254432.SCE1572_37385	1.864e-128	419.0	COG0604@1|root,COG0604@2|Bacteria,1MX8A@1224|Proteobacteria,42QBD@68525|delta/epsilon subdivisions,2WM4P@28221|Deltaproteobacteria,2YW8P@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N_2
SHD3_k127_1490544_0	1123393.KB891326_gene83	4.794e-239	752.0	COG1387@1|root,COG1387@2|Bacteria,1MYXV@1224|Proteobacteria,2VJIQ@28216|Betaproteobacteria,1KSJ5@119069|Hydrogenophilales	119069|Hydrogenophilales	L	DNA polymerase X family	-	-	-	ko:K02347	-	-	-	-	ko00000,ko03400	-	-	-	DNA_pol_B_thumb,HHH_5,HHH_8
SHD3_k127_1490544_5	1242864.D187_004487	0.0003683	45.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WRBN@28221|Deltaproteobacteria,2Z0B0@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SHD3_k127_1490544_2	448385.sce4512	1.389e-80	280.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1490544_6	443144.GM21_0397	0.0004151	53.0	COG3005@1|root,COG3005@2|Bacteria,1R4UP@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome C family protein	mtrA	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
SHD3_k127_1490544_4	290397.Adeh_3067	4.371e-14	86.0	COG3043@1|root,COG3043@2|Bacteria,1RG8Q@1224|Proteobacteria,42S2W@68525|delta/epsilon subdivisions,2WNP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c	pccJ	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SHD3_k127_1490544_3	1121920.AUAU01000012_gene2646	2.602e-32	139.0	COG0509@1|root,COG2204@1|root,COG0509@2|Bacteria,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GAF_2,GCV_H,Response_reg
SHD3_k127_1500838_2	502025.Hoch_4498	1.322e-44	166.0	COG0537@1|root,COG0537@2|Bacteria,1PDTP@1224|Proteobacteria,42UAD@68525|delta/epsilon subdivisions,2WS0J@28221|Deltaproteobacteria,2Z2ZP@29|Myxococcales	28221|Deltaproteobacteria	FG	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
SHD3_k127_1500838_1	1137799.GZ78_01455	8.276e-54	198.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	-	-	3.6.1.13,3.6.1.55	ko:K01515,ko:K03574	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4743,NUDIX
SHD3_k127_1500838_3	1192034.CAP_1508	1.177e-19	103.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,2YU0X@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_1500838_0	1394178.AWOO02000081_gene2194	1.113e-149	496.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,4EG6Y@85012|Streptosporangiales	201174|Actinobacteria	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SHD3_k127_1503430_1	351746.Pput_0821	2.369e-26	121.0	COG2199@1|root,COG3706@2|Bacteria,1MWHH@1224|Proteobacteria,1S12M@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	(GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
SHD3_k127_1512765_1	1192034.CAP_4938	7.1e-42	168.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	3.4.21.19	ko:K01318	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Trypsin,Trypsin_2
SHD3_k127_1512765_0	298655.KI912266_gene2891	3.403e-123	450.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
SHD3_k127_1514942_7	864051.BurJ1DRAFT_2685	7.66e-74	263.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,2WFJG@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Cytochrome b/b6/petB	-	-	-	-	-	-	-	-	-	-	-	-	Ni_hydr_CYTB
SHD3_k127_1514942_8	566466.NOR53_1656	6.116e-60	215.0	COG4117@1|root,COG4117@2|Bacteria,1R4HB@1224|Proteobacteria,1RSIU@1236|Gammaproteobacteria,1JBRF@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Prokaryotic cytochrome b561	ydhU	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08354	ko00920,ko01120,map00920,map01120	-	R10149	RC02823	ko00000,ko00001,ko02000	5.A.3.5	-	-	Cytochrome_C7,Ni_hydr_CYTB
SHD3_k127_1514942_11	880073.Calab_2452	1.15e-46	177.0	COG2391@1|root,COG2391@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
SHD3_k127_1514942_10	566466.NOR53_798	3.799e-58	207.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1J96D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Rhodanese,Sulf_transp
SHD3_k127_1514942_15	314285.KT71_18446	6.612e-21	108.0	COG2391@1|root,COG2391@2|Bacteria,1RIWE@1224|Proteobacteria,1S93K@1236|Gammaproteobacteria,1J96D@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Rhodanese,Sulf_transp
SHD3_k127_1514942_16	518766.Rmar_1296	7.673e-16	84.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspA	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SHD3_k127_1514942_14	264462.Bd2165	1.035e-22	103.0	COG1765@1|root,COG1765@2|Bacteria,1RCZW@1224|Proteobacteria,42VTN@68525|delta/epsilon subdivisions,2WRRM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	OsmC
SHD3_k127_1514942_6	1192034.CAP_1200	5.36e-78	278.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_1200|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1514942_9	1123508.JH636440_gene2902	1.303e-59	222.0	COG2203@1|root,COG4191@1|root,COG2203@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_1514942_3	765911.Thivi_0635	5.413e-129	418.0	COG2086@1|root,COG2086@2|Bacteria,1MVH6@1224|Proteobacteria,1RN6F@1236|Gammaproteobacteria,1WW5F@135613|Chromatiales	135613|Chromatiales	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
SHD3_k127_1514942_2	880073.Calab_2104	5.055e-154	493.0	COG2025@1|root,COG2025@2|Bacteria,2NNR6@2323|unclassified Bacteria	2|Bacteria	C	Electron transfer flavoprotein	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha,Fer4
SHD3_k127_1514942_0	880073.Calab_2105	1.096e-232	737.0	COG1960@1|root,COG1960@2|Bacteria,2NNRN@2323|unclassified Bacteria	2|Bacteria	I	Dehydrogenase	acd	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.3.8.1,1.3.8.7	ko:K00248,ko:K00249,ko:K20035	ko00071,ko00280,ko00410,ko00640,ko00650,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map00920,map01100,map01110,map01120,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754,R11130	RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246,RC03363	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_C,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_DH_N
SHD3_k127_1514942_18	448385.sce7744	1.517e-10	74.0	COG3266@1|root,COG3266@2|Bacteria,1QA9E@1224|Proteobacteria,434X4@68525|delta/epsilon subdivisions,2WZ81@28221|Deltaproteobacteria,2Z1J2@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1514942_12	1254432.SCE1572_02320	1.758e-41	161.0	COG1595@1|root,COG1595@2|Bacteria,1QR72@1224|Proteobacteria,43E0Y@68525|delta/epsilon subdivisions,2WZDM@28221|Deltaproteobacteria,2Z1WN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_1514942_17	448385.sce1339	1.348e-12	78.0	2AJJV@1|root,31A6Q@2|Bacteria,1Q51M@1224|Proteobacteria,435IH@68525|delta/epsilon subdivisions,2WZW5@28221|Deltaproteobacteria,2Z2VC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1514942_4	1254432.SCE1572_21215	1.242e-120	409.0	COG2730@1|root,COG2730@2|Bacteria,1R2BZ@1224|Proteobacteria	1224|Proteobacteria	G	Glycoside hydrolase family 44	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_44
SHD3_k127_1514942_5	1254432.SCE1572_21065	2.495e-82	282.0	COG1409@1|root,COG1409@2|Bacteria,1R7FF@1224|Proteobacteria	1224|Proteobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,Metallophos_2
SHD3_k127_1514942_1	483219.LILAB_16030	6.514e-207	661.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2WK62@28221|Deltaproteobacteria,2YWZ7@29|Myxococcales	28221|Deltaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
SHD3_k127_1519550_1	404589.Anae109_0627	2.236e-12	72.0	2ANPU@1|root,31DPC@2|Bacteria,1QB0N@1224|Proteobacteria,435DB@68525|delta/epsilon subdivisions,2WZQX@28221|Deltaproteobacteria,2Z2JD@29|Myxococcales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SHD3_k127_1519550_2	479434.Sthe_1131	8.862e-06	57.0	2DYB6@1|root,3490S@2|Bacteria	479434.Sthe_1131|-	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1519550_0	370438.PTH_0496	6.298e-16	84.0	COG0043@1|root,COG0043@2|Bacteria,1TQ6V@1239|Firmicutes,248WY@186801|Clostridia,260E4@186807|Peptococcaceae	186801|Clostridia	H	Belongs to the UbiD family	-	-	-	ko:K16874	ko00365,ko01120,map00365,map01120	-	R10213	RC03086	ko00000,ko00001	-	-	-	UbiD
SHD3_k127_1554649_3	296587.XP_002506940.1	2.515e-31	133.0	COG5184@1|root,KOG1426@2759|Eukaryota	2759|Eukaryota	DZ	guanyl-nucleotide exchange factor activity	RCCD1	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_1554649_2	1192034.CAP_8267	1.014e-61	226.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	68525|delta/epsilon subdivisions	KLT	Family membership	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PP2C_2,Pkinase
SHD3_k127_1554649_1	485913.Krac_9455	1.351e-126	414.0	COG0667@1|root,COG0667@2|Bacteria,2G6BF@200795|Chloroflexi	2|Bacteria	C	PFAM aldo keto reductase	-	-	1.1.1.91	ko:K05882	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
SHD3_k127_1554649_0	1254432.SCE1572_33040	1.036e-141	464.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42MCH@68525|delta/epsilon subdivisions,2WJPZ@28221|Deltaproteobacteria,2Z39Q@29|Myxococcales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SHD3_k127_1567033_3	290397.Adeh_3529	9.44e-109	380.0	COG0642@1|root,COG0784@1|root,COG2461@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,43CCU@68525|delta/epsilon subdivisions,2X7NQ@28221|Deltaproteobacteria,2YX99@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_1567033_4	502025.Hoch_4790	1.174e-102	352.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YYCB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_1567033_5	448385.sce0652	5.533e-95	329.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SHD3_k127_1567033_2	404589.Anae109_1656	3.464e-123	404.0	COG1294@1|root,COG1294@2|Bacteria,1MURP@1224|Proteobacteria,42NHN@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	Cytochrome d ubiquinol oxidase, subunit II	cydB	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	iECABU_c1320.ECABU_c10120,iLF82_1304.LF82_0101,iNRG857_1313.NRG857_04455,iPC815.YPO1118,ic_1306.c1120	Cyt_bd_oxida_II
SHD3_k127_1567033_1	756272.Plabr_1583	2.945e-171	550.0	COG1271@1|root,COG1271@2|Bacteria,2IXYC@203682|Planctomycetes	203682|Planctomycetes	C	Cytochrome bd-type quinol oxidase subunit 1	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
SHD3_k127_1567033_0	290397.Adeh_2962	8.531e-247	792.0	COG0574@1|root,COG0574@2|Bacteria,1N38V@1224|Proteobacteria,42MWC@68525|delta/epsilon subdivisions,2WKAZ@28221|Deltaproteobacteria,2Z1W9@29|Myxococcales	28221|Deltaproteobacteria	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PPDK_N
SHD3_k127_1567033_6	1232410.KI421422_gene1956	4.649e-05	48.0	COG2204@1|root,COG2204@2|Bacteria,1NABF@1224|Proteobacteria,43C0I@68525|delta/epsilon subdivisions,2X7B5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_1570741_3	290397.Adeh_2902	7.262e-64	225.0	COG3303@1|root,COG3303@2|Bacteria,1MVJT@1224|Proteobacteria,42MPU@68525|delta/epsilon subdivisions,2WIJ1@28221|Deltaproteobacteria,2YUSH@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	nrfA	-	1.7.2.2	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	M00530	R05712	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytochrom_C552
SHD3_k127_1570741_6	338963.Pcar_2867	2.632e-49	181.0	COG3005@1|root,COG3005@2|Bacteria,1N0I4@1224|Proteobacteria,42R1B@68525|delta/epsilon subdivisions,2WQMW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	NapC/NirT cytochrome c family, N-terminal region	nrfH	-	-	ko:K15876	ko00910,ko01120,map00910,map01120	M00530	R05712	RC00176	ko00000,ko00001,ko00002	-	-	-	Cytochrom_NNT
SHD3_k127_1570741_8	1254432.SCE1572_03625	6.12e-23	113.0	COG3391@1|root,COG3591@1|root,COG3391@2|Bacteria,COG3591@2|Bacteria,1R0BE@1224|Proteobacteria,43CTP@68525|delta/epsilon subdivisions,2X817@28221|Deltaproteobacteria,2Z05E@29|Myxococcales	28221|Deltaproteobacteria	E	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_1570741_10	1242864.D187_006227	1.51e-14	87.0	COG2730@1|root,COG4447@1|root,COG2730@2|Bacteria,COG4447@2|Bacteria,1R5GC@1224|Proteobacteria,434P8@68525|delta/epsilon subdivisions,2WZ0H@28221|Deltaproteobacteria,2Z12C@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_1570741_5	404589.Anae109_2058	1.528e-58	214.0	COG3644@1|root,COG3644@2|Bacteria,1RK12@1224|Proteobacteria,436NH@68525|delta/epsilon subdivisions,2X1AB@28221|Deltaproteobacteria,2Z1B2@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized protein conserved in bacteria (DUF2239)	-	-	-	ko:K09965	-	-	-	-	ko00000	-	-	-	DUF2239
SHD3_k127_1570741_0	483219.LILAB_30950	4.909e-200	645.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WJ41@28221|Deltaproteobacteria,2YUJJ@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter, ATP-binding protein	ybiT	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SHD3_k127_1570741_7	1123508.JH636445_gene6636	4.442e-46	175.0	COG5478@1|root,COG5478@2|Bacteria,2J05Z@203682|Planctomycetes	203682|Planctomycetes	S	Low affinity iron permease	-	-	-	-	-	-	-	-	-	-	-	-	Iron_permease
SHD3_k127_1570741_1	251229.Chro_3079	4.049e-88	301.0	COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,3VJ5H@52604|Pleurocapsales	1117|Cyanobacteria	S	TIGRFAM YihY family protein (not ribonuclease BN)	rbn	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SHD3_k127_1570741_2	391625.PPSIR1_28478	1.268e-77	273.0	COG0607@1|root,COG3258@1|root,COG0607@2|Bacteria,COG3258@2|Bacteria	2|Bacteria	C	Cytochrome c	soxA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564	1.8.2.2	ko:K00406,ko:K03889,ko:K17222,ko:K19713	ko00190,ko00920,ko01100,ko01120,ko02020,map00190,map00920,map01100,map01120,map02020	M00151,M00156,M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cytochrome_CBB3,Rhodanese
SHD3_k127_1570741_4	448385.sce1485	4.883e-63	225.0	COG3507@1|root,COG3507@2|Bacteria,1R3V6@1224|Proteobacteria,43A5N@68525|delta/epsilon subdivisions,2X50Q@28221|Deltaproteobacteria,2YZY6@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
SHD3_k127_1576033_3	1254432.SCE1572_00345	5.377e-45	172.0	2EI76@1|root,33BYI@2|Bacteria,1RBW7@1224|Proteobacteria,42QZD@68525|delta/epsilon subdivisions,2WN6J@28221|Deltaproteobacteria,2YXMN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1576033_0	1254432.SCE1572_51350	6.546e-152	514.0	COG1196@1|root,COG1196@2|Bacteria,1QX9X@1224|Proteobacteria,43018@68525|delta/epsilon subdivisions,2WVD9@28221|Deltaproteobacteria,2YW2N@29|Myxococcales	28221|Deltaproteobacteria	D	Domain of unknown function (DUF4175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4175
SHD3_k127_1576033_1	1192034.CAP_2106	6.501e-109	372.0	COG0308@1|root,COG0308@2|Bacteria,1RBHC@1224|Proteobacteria,42QWW@68525|delta/epsilon subdivisions,2WMP2@28221|Deltaproteobacteria,2YUU2@29|Myxococcales	28221|Deltaproteobacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19
SHD3_k127_1576033_2	448385.sce9033	7.653e-79	272.0	COG0688@1|root,COG0688@2|Bacteria,1MVT4@1224|Proteobacteria,42PAW@68525|delta/epsilon subdivisions,2WJV9@28221|Deltaproteobacteria,2Z0GD@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
SHD3_k127_158634_0	1254432.SCE1572_00625	4.053e-154	490.0	2DMP1@1|root,32SS8@2|Bacteria,1N6W6@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
SHD3_k127_158634_2	243231.GSU2816	4.793e-135	452.0	COG2204@1|root,COG4191@1|root,COG5000@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,COG5000@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria,43TMC@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_158634_1	1380394.JADL01000026_gene4735	9.746e-145	473.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,2TR6Q@28211|Alphaproteobacteria,2JQDT@204441|Rhodospirillales	204441|Rhodospirillales	JKL	Belongs to the DEAD box helicase family	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
SHD3_k127_158634_10	378806.STAUR_6021	7.138e-07	53.0	2AGWF@1|root,3174U@2|Bacteria,1PYDK@1224|Proteobacteria,435AC@68525|delta/epsilon subdivisions,2WZMD@28221|Deltaproteobacteria,2Z2DC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_158634_7	3711.Bra037056.1-P	4.019e-28	117.0	KOG0118@1|root,KOG0118@2759|Eukaryota,37V6P@33090|Viridiplantae,3GJFA@35493|Streptophyta	35493|Streptophyta	A	Glycine-rich RNA-binding protein	-	GO:0000166,GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003723,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006355,GO:0006950,GO:0006970,GO:0007275,GO:0008144,GO:0008150,GO:0009266,GO:0009409,GO:0009414,GO:0009415,GO:0009628,GO:0009631,GO:0009651,GO:0009791,GO:0009845,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031554,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034336,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043242,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0060567,GO:0065007,GO:0080090,GO:0090351,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	RRM_1
SHD3_k127_158634_3	1192034.CAP_3408	5.843e-123	410.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SHD3_k127_158634_6	1192034.CAP_2110	2.129e-37	162.0	COG0454@1|root,COG0456@2|Bacteria,1PC8S@1224|Proteobacteria,438AY@68525|delta/epsilon subdivisions,2X1TU@28221|Deltaproteobacteria,2YWEB@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SHD3_k127_158634_5	404589.Anae109_1730	1.413e-66	236.0	COG0421@1|root,COG0421@2|Bacteria,1QUUH@1224|Proteobacteria,42MJV@68525|delta/epsilon subdivisions,2WMKH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	cog0421, spermidine synthase	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
SHD3_k127_158634_8	448385.sce7258	4.672e-27	113.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria,2YW65@29|Myxococcales	28221|Deltaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SHD3_k127_158634_4	706587.Desti_3183	1.07e-81	301.0	COG2202@1|root,COG4191@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4191@2|Bacteria,COG4251@2|Bacteria,1RCM9@1224|Proteobacteria,42QA2@68525|delta/epsilon subdivisions,2X7QC@28221|Deltaproteobacteria,2MQRX@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,MASE3,PAS_9
SHD3_k127_158634_9	555088.DealDRAFT_1586	3.237e-11	64.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,42KR8@68298|Syntrophomonadaceae	186801|Clostridia	T	Integral membrane sensor signal transduction histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	DUF3365,HAMP,HATPase_c,HisKA,Hpt,MASE3,PAS,PAS_9,Response_reg
SHD3_k127_1597988_7	502025.Hoch_6593	6.44e-28	128.0	COG0745@1|root,COG2202@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_1597988_1	1306174.JODP01000016_gene7147	2.356e-121	417.0	COG5184@1|root,COG5184@2|Bacteria,2IG31@201174|Actinobacteria	201174|Actinobacteria	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,RCC1,RCC1_2
SHD3_k127_1597988_4	1131812.JQMS01000001_gene3149	2.695e-101	342.0	COG2730@1|root,COG2730@2|Bacteria,4NIBG@976|Bacteroidetes,1HYT8@117743|Flavobacteriia,2NU0X@237|Flavobacterium	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	eglS	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
SHD3_k127_1597988_6	515635.Dtur_1753	4.617e-40	168.0	COG1609@1|root,COG2199@1|root,COG2203@1|root,COG2206@1|root,COG1609@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	rpfG_3	-	-	ko:K02030,ko:K02103,ko:K02529	-	M00236	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1.3	-	-	GAF_2,GGDEF,HD,HD_5,HisKA_7TM,Peripla_BP_3
SHD3_k127_1597988_8	398512.JQKC01000012_gene240	0.0005063	50.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,3WKRD@541000|Ruminococcaceae	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
SHD3_k127_1597988_5	861299.J421_0973	5.078e-81	273.0	COG3548@1|root,COG3548@2|Bacteria	2|Bacteria	S	protein homotetramerization	yiiE	-	-	-	-	-	-	-	-	-	-	-	DUF1211
SHD3_k127_1597988_0	448385.sce3277	9.416e-128	429.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,437EK@68525|delta/epsilon subdivisions,2XA2I@28221|Deltaproteobacteria,2Z0XV@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
SHD3_k127_1597988_3	760568.Desku_2810	4.128e-102	346.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,261GJ@186807|Peptococcaceae	186801|Clostridia	S	associated with various cellular activities	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SHD3_k127_162338_3	1192034.CAP_0179	3.917e-84	290.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_0179|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_162338_0	1192034.CAP_0180	0.0	4269.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG5373@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,COG5373@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_7,TPR_8
SHD3_k127_162338_4	1192034.CAP_7576	2.158e-70	260.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43CK3@68525|delta/epsilon subdivisions,2X7UI@28221|Deltaproteobacteria,2YYPR@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_162338_6	1192034.CAP_6952	2.356e-32	141.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_6952|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_162338_2	1254432.SCE1572_22755	1.013e-117	410.0	COG0860@1|root,COG0860@2|Bacteria,1MUQK@1224|Proteobacteria,42MPH@68525|delta/epsilon subdivisions,2WJHW@28221|Deltaproteobacteria,2Z0ST@29|Myxococcales	28221|Deltaproteobacteria	M	Ami_3	amiC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	AMIN,Amidase_3,TPR_6
SHD3_k127_162338_5	1192034.CAP_6945	2.583e-55	196.0	COG1734@1|root,COG1734@2|Bacteria,1N8RB@1224|Proteobacteria,42W5H@68525|delta/epsilon subdivisions,2WSAD@28221|Deltaproteobacteria,2YVJ6@29|Myxococcales	28221|Deltaproteobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SHD3_k127_162338_1	644282.Deba_2729	1.278e-264	835.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SHD3_k127_1629536_2	102125.Xen7305DRAFT_00015430	1.054e-90	318.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	CP_0674	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,PTS_EIIA_2
SHD3_k127_1629536_0	448385.sce3970	0.0	1660.0	COG1201@1|root,COG2345@1|root,COG1201@2|Bacteria,COG2345@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YU11@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
SHD3_k127_1629536_5	1278073.MYSTI_07754	2.122e-38	155.0	COG1595@1|root,COG1595@2|Bacteria,1Q2GH@1224|Proteobacteria,43830@68525|delta/epsilon subdivisions,2X0DG@28221|Deltaproteobacteria,2YVH2@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-binding regulatory protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_1629536_4	1192034.CAP_0612	1.063e-59	224.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_0612|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1629536_1	404380.Gbem_0793	4.172e-93	330.0	COG2204@1|root,COG3852@1|root,COG4191@1|root,COG2204@2|Bacteria,COG3852@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg,dCache_1
SHD3_k127_1629536_3	44251.PDUR_11565	1.698e-80	287.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MatE
SHD3_k127_1629536_6	1192034.CAP_3140	2.946e-28	116.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,2YVAC@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	yrdC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SHD3_k127_1641432_3	448385.sce7410	3.124e-33	134.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,43A9U@68525|delta/epsilon subdivisions,2X244@28221|Deltaproteobacteria,2Z171@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:RRM_6	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SHD3_k127_1641432_2	448385.sce0876	4.737e-91	322.0	COG1716@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315,ko:K16922	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01002,ko03021	-	-	-	CHASE2,FHA,GAF_2,HATPase_c_2,SpoIIE,Yop-YscD_cpl
SHD3_k127_1641432_0	502025.Hoch_5958	2.521e-264	885.0	COG0457@1|root,COG0457@2|Bacteria,1PC8F@1224|Proteobacteria,438AR@68525|delta/epsilon subdivisions,2X3K3@28221|Deltaproteobacteria,2YWDI@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SHD3_k127_1641432_4	1237149.C900_02200	4.508e-17	94.0	COG2885@1|root,COG2885@2|Bacteria,4NRQ3@976|Bacteroidetes,47S5T@768503|Cytophagia	976|Bacteroidetes	M	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
SHD3_k127_1641432_1	1192034.CAP_7045	1.119e-111	368.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1656069_8	266779.Meso_1391	2.758e-65	235.0	COG1043@1|root,COG1043@2|Bacteria,1MUHQ@1224|Proteobacteria,2TRK9@28211|Alphaproteobacteria,43HH5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxA	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
SHD3_k127_1656069_9	1254432.SCE1572_17495	6.064e-59	206.0	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,42SCN@68525|delta/epsilon subdivisions,2WP3E@28221|Deltaproteobacteria,2YVDF@29|Myxococcales	28221|Deltaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
SHD3_k127_1656069_11	1307759.JOMJ01000004_gene2986	9.909e-40	160.0	COG1044@1|root,COG1044@2|Bacteria,1MUX6@1224|Proteobacteria,42M4X@68525|delta/epsilon subdivisions,2WJJY@28221|Deltaproteobacteria,2M7TA@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2,LpxD
SHD3_k127_1656069_10	1254432.SCE1572_17500	4.558e-51	188.0	COG2825@1|root,COG2825@2|Bacteria,1MZVJ@1224|Proteobacteria,42VH3@68525|delta/epsilon subdivisions,2WP6K@28221|Deltaproteobacteria,2YVZ7@29|Myxococcales	28221|Deltaproteobacteria	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
SHD3_k127_1656069_2	448385.sce0061	1.941e-106	367.0	COG2905@1|root,COG2905@2|Bacteria,1R0B9@1224|Proteobacteria,43CTI@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	DUF4388,cNMP_binding
SHD3_k127_1656069_6	1254432.SCE1572_32035	1.598e-82	294.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_1656069_4	163908.KB235896_gene2775	1.196e-91	303.0	COG0652@1|root,COG0652@2|Bacteria,1G5BD@1117|Cyanobacteria,1HMQV@1161|Nostocales	1117|Cyanobacteria	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	rot	-	5.2.1.8	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SHD3_k127_1656069_5	56780.SYN_02762	3.243e-88	309.0	COG1624@1|root,COG4856@1|root,COG1624@2|Bacteria,COG4856@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	-	-	-	-	-	-	-	-	-	-	DisA_N,YbbR
SHD3_k127_1656069_3	448385.sce0010	7.797e-101	341.0	COG1420@1|root,COG1420@2|Bacteria,1MVX4@1224|Proteobacteria,42MTI@68525|delta/epsilon subdivisions,2WIXW@28221|Deltaproteobacteria,2YUQ9@29|Myxococcales	28221|Deltaproteobacteria	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
SHD3_k127_1656069_7	1192034.CAP_7807	1.703e-66	234.0	COG0669@1|root,COG0669@2|Bacteria,1RD9F@1224|Proteobacteria,42RJQ@68525|delta/epsilon subdivisions,2WNDS@28221|Deltaproteobacteria,2YYUB@29|Myxococcales	28221|Deltaproteobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
SHD3_k127_1656069_0	1192034.CAP_7801	1.196e-146	477.0	2BS7F@1|root,32M8R@2|Bacteria,1Q33Y@1224|Proteobacteria,433XP@68525|delta/epsilon subdivisions,2X2HG@28221|Deltaproteobacteria,2YXTX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1659245_0	1254432.SCE1572_20280	4.481e-82	288.0	COG3693@1|root,COG3693@2|Bacteria,1R7BZ@1224|Proteobacteria	1224|Proteobacteria	G	Beta-xylanase	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM60,CBM_10,CBM_2,CBM_4_9,CBM_5_12_2,CBM_6,Glyco_hydro_10,Glyco_hydro_43,SASA
SHD3_k127_1660690_2	1192034.CAP_3140	1.258e-38	147.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,42QSV@68525|delta/epsilon subdivisions,2WMZ5@28221|Deltaproteobacteria,2YVAC@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the SUA5 family	yrdC	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	Sua5_yciO_yrdC
SHD3_k127_1660690_1	448385.sce2058	2.074e-54	207.0	2B33H@1|root,31VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1660690_0	1254432.SCE1572_00180	6.225e-156	508.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YUHY@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
SHD3_k127_1660919_1	562970.Btus_2172	1.246e-110	372.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli,2781Y@186823|Alicyclobacillaceae	91061|Bacilli	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU34910	Histidinol_dh
SHD3_k127_1660919_0	448385.sce8989	3.795e-150	502.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_1675914_7	1116472.MGMO_135c00020	2.444e-76	270.0	COG3391@1|root,COG3391@2|Bacteria,1MY07@1224|Proteobacteria,1TI0G@1236|Gammaproteobacteria,1XG7U@135618|Methylococcales	135618|Methylococcales	M	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1675914_9	391603.FBALC1_14667	2.827e-25	113.0	COG5580@1|root,COG5580@2|Bacteria,4PK53@976|Bacteroidetes,1I3SX@117743|Flavobacteriia	976|Bacteroidetes	O	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SHD3_k127_1675914_3	290397.Adeh_2972	2.081e-140	457.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2YWS4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SHD3_k127_1675914_6	1242864.D187_001641	7.827e-98	326.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42P96@68525|delta/epsilon subdivisions,2WMVB@28221|Deltaproteobacteria,2YUCK@29|Myxococcales	28221|Deltaproteobacteria	P	Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_1675914_2	1192034.CAP_4198	2.275e-156	507.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWC8@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SHD3_k127_1675914_5	290397.Adeh_2969	3.41e-118	394.0	COG1538@1|root,COG1538@2|Bacteria,1MWX5@1224|Proteobacteria,42SGU@68525|delta/epsilon subdivisions,2WPBP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	MU	CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin)	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
SHD3_k127_1675914_4	383372.Rcas_3626	1.098e-138	453.0	COG0477@1|root,COG0477@2|Bacteria,2GA6R@200795|Chloroflexi,3782R@32061|Chloroflexia	32061|Chloroflexia	EGP	major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SHD3_k127_1675914_1	243231.GSU1105	3.209e-157	505.0	COG0006@1|root,COG0006@2|Bacteria,1MVJK@1224|Proteobacteria,43DQS@68525|delta/epsilon subdivisions,2X6WA@28221|Deltaproteobacteria,43S6S@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
SHD3_k127_1675914_0	404589.Anae109_3461	1.687e-306	951.0	COG0365@1|root,COG0365@2|Bacteria,1MUF5@1224|Proteobacteria,42MHP@68525|delta/epsilon subdivisions,2WIQG@28221|Deltaproteobacteria,2YUFQ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA	acsA	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
SHD3_k127_1675914_10	351160.RCIX1408	5.212e-20	98.0	COG0727@1|root,arCOG02579@2157|Archaea	2157|Archaea	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SHD3_k127_1675914_8	80884.CCF47345	1.348e-30	132.0	2CAP4@1|root,2QQXU@2759|Eukaryota,39KSE@33154|Opisthokonta,3NWM7@4751|Fungi,3QMRM@4890|Ascomycota,214QD@147550|Sordariomycetes,1EYMG@1028384|Glomerellales	4751|Fungi	S	Cellulose-binding family ii	-	-	-	-	-	-	-	-	-	-	-	-	CBM_1
SHD3_k127_1687225_2	867845.KI911784_gene654	3.418e-43	160.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_1687225_1	1192034.CAP_7471	7.916e-79	279.0	COG0457@1|root,COG0457@2|Bacteria,1N5BD@1224|Proteobacteria,42U63@68525|delta/epsilon subdivisions,2WQUR@28221|Deltaproteobacteria,2YUQA@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_4,TPR_8
SHD3_k127_1687225_0	1254432.SCE1572_42990	3.528e-125	427.0	COG0739@1|root,COG0739@2|Bacteria,1MVTF@1224|Proteobacteria,42MNF@68525|delta/epsilon subdivisions,2WIYR@28221|Deltaproteobacteria,2YV41@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SHD3_k127_1687225_4	1254432.SCE1572_09125	4.232e-24	119.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
SHD3_k127_1687225_5	448385.sce2186	1.374e-15	89.0	COG1729@1|root,COG1729@2|Bacteria,1PYP2@1224|Proteobacteria,435GR@68525|delta/epsilon subdivisions,2WZU6@28221|Deltaproteobacteria,2Z2RR@29|Myxococcales	28221|Deltaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SHD3_k127_1687225_3	448385.sce2185	5.187e-27	121.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_169731_6	290397.Adeh_0078	9.313e-38	153.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_169731_1	1254432.SCE1572_43140	2.125e-131	431.0	COG0379@1|root,COG0379@2|Bacteria,1MWQU@1224|Proteobacteria,42N99@68525|delta/epsilon subdivisions,2WJY8@28221|Deltaproteobacteria,2YTVB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
SHD3_k127_169731_4	1192034.CAP_2501	1.538e-96	324.0	COG0345@1|root,COG0345@2|Bacteria,1R5J1@1224|Proteobacteria,42P7F@68525|delta/epsilon subdivisions,2WJW9@28221|Deltaproteobacteria,2YTWD@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0899	F420_oxidored,P5CR_dimer
SHD3_k127_169731_2	1192034.CAP_2594	3.573e-120	396.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2YXG3@29|Myxococcales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SHD3_k127_169731_3	290397.Adeh_4217	2.613e-105	374.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MIZ@68525|delta/epsilon subdivisions,2X2UJ@28221|Deltaproteobacteria,2YZ7G@29|Myxococcales	28221|Deltaproteobacteria	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SHD3_k127_169731_7	886293.Sinac_7121	2.228e-25	124.0	COG0745@1|root,COG5002@1|root,COG5278@1|root,COG0745@2|Bacteria,COG5002@2|Bacteria,COG5278@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_169731_5	1254432.SCE1572_34860	4.823e-46	177.0	COG3215@1|root,COG3215@2|Bacteria,1Q2S4@1224|Proteobacteria,43266@68525|delta/epsilon subdivisions,2WXR8@28221|Deltaproteobacteria,2YVFJ@29|Myxococcales	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	ko:K02676	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilZ
SHD3_k127_1713917_2	903818.KI912268_gene1836	6.524e-39	157.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SHD3_k127_1713917_0	448385.sce6068	1.364e-108	374.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
SHD3_k127_1713917_1	1169144.KB910935_gene2035	7.273e-65	229.0	COG1388@1|root,COG1388@2|Bacteria,1V4GT@1239|Firmicutes,4IPSP@91061|Bacilli	91061|Bacilli	M	LysM domain	M1-670	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1713917_3	391625.PPSIR1_31893	1.572e-28	123.0	COG1629@1|root,COG4771@2|Bacteria,1QX4E@1224|Proteobacteria,437VM@68525|delta/epsilon subdivisions,2X358@28221|Deltaproteobacteria,2YUBU@29|Myxococcales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_C,TonB_dep_Rec
SHD3_k127_1726249_2	1196322.A370_03622	3.437e-27	111.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,36E7J@31979|Clostridiaceae	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
SHD3_k127_1726249_3	215803.DB30_0451	1.43e-15	85.0	COG3064@1|root,COG3215@1|root,COG3064@2|Bacteria,COG3215@2|Bacteria,1Q3B9@1224|Proteobacteria,4392F@68525|delta/epsilon subdivisions,2X485@28221|Deltaproteobacteria,2YYGF@29|Myxococcales	28221|Deltaproteobacteria	MNU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SHD3_k127_1726249_0	631362.Thi970DRAFT_00097	1.347e-84	296.0	COG0701@1|root,COG0701@2|Bacteria,1MUN8@1224|Proteobacteria,1RSPM@1236|Gammaproteobacteria,1WYFN@135613|Chromatiales	135613|Chromatiales	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1,HMA
SHD3_k127_1726249_1	1242864.D187_010311	1.86e-30	129.0	COG0663@1|root,COG0663@2|Bacteria,1Q0SI@1224|Proteobacteria,439EX@68525|delta/epsilon subdivisions,2X4Q4@28221|Deltaproteobacteria,2YZDQ@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1730112_3	105422.BBPM01000102_gene5259	5.872e-23	107.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	-	-	-	-	-	-	-	-	-	-	-	-	He_PIG,PLDc_2
SHD3_k127_1730112_1	1121015.N789_07695	4.856e-61	221.0	arCOG09454@1|root,30G4A@2|Bacteria,1N61J@1224|Proteobacteria,1SRHG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1730112_0	35754.JNYJ01000027_gene6142	1.163e-115	387.0	COG2755@1|root,COG5297@1|root,COG2755@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria,4DCHA@85008|Micromonosporales	201174|Actinobacteria	EG	Alpha-L-arabinofuranosidase B, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_1730112_4	398512.JQKC01000017_gene3048	4.037e-07	55.0	COG3507@1|root,COG3507@2|Bacteria,1TR04@1239|Firmicutes,24ATC@186801|Clostridia,3WG7I@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	AbfB,Big_3,CBM_2,CBM_4_9,CBM_6,Dockerin_1,Esterase,Glyco_hydro_43,RicinB_lectin_2
SHD3_k127_1730112_2	1514668.JOOA01000001_gene744	2.787e-25	116.0	COG0726@1|root,COG3693@1|root,COG0726@2|Bacteria,COG3693@2|Bacteria,1UPM6@1239|Firmicutes,25HJ2@186801|Clostridia,3WRPB@541000|Ruminococcaceae	2|Bacteria	G	Glycosyl hydrolases family 11	-	GO:0003674,GO:0003824,GO:0004099,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0019213,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.5.1.105	ko:K18454	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,CelD_N,Glyco_hydro_10,Glyco_hydro_11,Glyco_hydro_2_N,Glyco_hydro_9,Polysacc_deac_1,SASA
SHD3_k127_1734271_3	1192034.CAP_6254	2.42e-134	449.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SHD3_k127_1734271_2	448385.sce7216	1.301e-158	506.0	COG2255@1|root,COG2255@2|Bacteria,1MU38@1224|Proteobacteria,42M99@68525|delta/epsilon subdivisions,2WJ2Q@28221|Deltaproteobacteria,2YUGW@29|Myxococcales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
SHD3_k127_1734271_21	694427.Palpr_1518	1.941e-08	61.0	COG0607@1|root,COG0607@2|Bacteria,4NXGV@976|Bacteroidetes,2FUKK@200643|Bacteroidia,22YWS@171551|Porphyromonadaceae	976|Bacteroidetes	P	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1734271_18	1042375.AFPL01000030_gene570	3.097e-11	67.0	COG1835@1|root,COG1835@2|Bacteria,1RFAU@1224|Proteobacteria,1RZVV@1236|Gammaproteobacteria,46914@72275|Alteromonadaceae	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SHD3_k127_1734271_19	1500893.JQNB01000001_gene1560	2.838e-10	66.0	COG1835@1|root,COG1835@2|Bacteria,1MYCR@1224|Proteobacteria,1SI9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SHD3_k127_1734271_11	489825.LYNGBM3L_75710	7.632e-54	210.0	COG0535@1|root,COG0535@2|Bacteria,1G4BU@1117|Cyanobacteria,1H9R7@1150|Oscillatoriales	1117|Cyanobacteria	C	4Fe-4S single cluster domain	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_1734271_9	631362.Thi970DRAFT_01668	1.32e-63	233.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pyrroloquinoline quinone biosynthesis protein E	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SHD3_k127_1734271_8	1120949.KB903335_gene9677	8.018e-65	231.0	COG0596@1|root,COG0596@2|Bacteria,2GKT5@201174|Actinobacteria,4DEB0@85008|Micromonosporales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SHD3_k127_1734271_4	266940.Krad_2880	1.34e-119	408.0	COG3420@1|root,COG3420@2|Bacteria,2H41I@201174|Actinobacteria	201174|Actinobacteria	P	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SHD3_k127_1734271_14	1254432.SCE1572_02320	1.519e-28	122.0	COG1595@1|root,COG1595@2|Bacteria,1QR72@1224|Proteobacteria,43E0Y@68525|delta/epsilon subdivisions,2WZDM@28221|Deltaproteobacteria,2Z1WN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_1734271_17	1254432.SCE1572_34760	2.966e-20	94.0	2A4V7@1|root,30TGT@2|Bacteria,1PDBB@1224|Proteobacteria,43E5P@68525|delta/epsilon subdivisions,2WZT2@28221|Deltaproteobacteria,2Z2PJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SPW
SHD3_k127_1734271_12	1380394.JADL01000003_gene5036	2.616e-46	173.0	COG4297@1|root,COG4297@2|Bacteria,1RB1W@1224|Proteobacteria,2U14J@28211|Alphaproteobacteria,2JTMM@204441|Rhodospirillales	204441|Rhodospirillales	S	protein containing double-stranded beta helix domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_1,Cupin_2
SHD3_k127_1734271_13	1121445.ATUZ01000013_gene1014	4.437e-41	164.0	COG3258@1|root,COG3258@2|Bacteria,1NIQK@1224|Proteobacteria,42MCQ@68525|delta/epsilon subdivisions,2X016@28221|Deltaproteobacteria,2M9NP@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome c	-	-	1.8.2.2	ko:K19713	-	-	-	-	ko00000,ko01000	-	-	-	Cytochrome_CBB3
SHD3_k127_1734271_5	1121441.AUCX01000008_gene2060	5.779e-86	306.0	COG1271@1|root,COG2010@1|root,COG1271@2|Bacteria,COG2010@2|Bacteria,1RE9S@1224|Proteobacteria,43ANP@68525|delta/epsilon subdivisions,2WTNU@28221|Deltaproteobacteria,2MGBN@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
SHD3_k127_1734271_6	665942.HMPREF1022_00933	6.581e-82	294.0	COG1271@1|root,COG1271@2|Bacteria,1PG1H@1224|Proteobacteria,437AC@68525|delta/epsilon subdivisions,2WUDD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SHD3_k127_1734271_7	1144275.COCOR_06605	2.505e-68	242.0	COG3880@1|root,COG3880@2|Bacteria,1RD55@1224|Proteobacteria,42TTE@68525|delta/epsilon subdivisions,2X777@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
SHD3_k127_1734271_0	1254432.SCE1572_27530	3.346e-297	939.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1MU1B@1224|Proteobacteria,42NEG@68525|delta/epsilon subdivisions,2WKHA@28221|Deltaproteobacteria,2YTUQ@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	actB	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding
SHD3_k127_1734271_1	1254432.SCE1572_27535	9.872e-191	608.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,2YUIA@29|Myxococcales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	actC	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SHD3_k127_1734271_10	1254432.SCE1572_27540	1.844e-55	203.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria,42WYA@68525|delta/epsilon subdivisions,2WT1Y@28221|Deltaproteobacteria,2Z3CC@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SHD3_k127_1734482_2	671143.DAMO_0756	1.344e-20	101.0	COG0477@1|root,COG2814@2|Bacteria,2NRCB@2323|unclassified Bacteria	2|Bacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
SHD3_k127_1734482_0	1192034.CAP_8957	6.86e-134	444.0	COG1192@1|root,COG1192@2|Bacteria,1QW1T@1224|Proteobacteria,43BRW@68525|delta/epsilon subdivisions,2X72Q@28221|Deltaproteobacteria,2YZTD@29|Myxococcales	28221|Deltaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SHD3_k127_1734482_1	1192034.CAP_8956	1.097e-28	128.0	29YZ3@1|root,30KW0@2|Bacteria,1QAV8@1224|Proteobacteria,435BG@68525|delta/epsilon subdivisions,2WZNV@28221|Deltaproteobacteria,2Z2FQ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1734482_3	1192034.CAP_2649	9.644e-10	66.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YV6N@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SHD3_k127_1738775_1	330214.NIDE0726	8.435e-193	642.0	COG0841@1|root,COG0841@2|Bacteria,3J0ZG@40117|Nitrospirae	40117|Nitrospirae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SHD3_k127_1738775_6	1403819.BATR01000128_gene4552	2.284e-15	88.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SHD3_k127_1738775_2	1278073.MYSTI_05044	2.062e-130	437.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJKZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_1738775_4	671143.DAMO_1544	3.783e-37	158.0	COG4191@1|root,COG4191@2|Bacteria,2NPGF@2323|unclassified Bacteria	2|Bacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_1738775_7	1122990.BAJH01000003_gene621	6.227e-14	85.0	COG0845@1|root,COG0845@2|Bacteria,4NERP@976|Bacteroidetes,2FPPN@200643|Bacteroidia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SHD3_k127_1738775_0	330214.NIDE0726	2.882e-194	651.0	COG0841@1|root,COG0841@2|Bacteria,3J0ZG@40117|Nitrospirae	40117|Nitrospirae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SHD3_k127_1738775_8	1254432.SCE1572_05450	2.748e-05	55.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	motB	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SHD3_k127_1738775_3	1192034.CAP_5604	4.096e-71	259.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
SHD3_k127_1741477_2	215803.DB30_5750	1.239e-52	201.0	COG4258@1|root,COG4258@2|Bacteria,1QX7Z@1224|Proteobacteria,43C13@68525|delta/epsilon subdivisions,2X7BR@28221|Deltaproteobacteria,2YU55@29|Myxococcales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SHD3_k127_1741477_4	1123354.AUDR01000017_gene46	2.588e-34	144.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,2VGZP@28216|Betaproteobacteria,1KRGS@119069|Hydrogenophilales	119069|Hydrogenophilales	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SHD3_k127_1741477_5	448385.sce3576	3.722e-28	116.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,42UCT@68525|delta/epsilon subdivisions,2WPAW@28221|Deltaproteobacteria,2YV7B@29|Myxococcales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SHD3_k127_1741477_6	1331060.RLDS_14975	2.733e-06	55.0	COG0782@1|root,COG0782@2|Bacteria,1RAP0@1224|Proteobacteria,2U75V@28211|Alphaproteobacteria,2K3X2@204457|Sphingomonadales	204457|Sphingomonadales	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length	greB	-	-	ko:K04760	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SHD3_k127_1741477_1	1192034.CAP_7115	4.157e-116	383.0	COG0240@1|root,COG0240@2|Bacteria	2|Bacteria	I	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
SHD3_k127_1741477_0	448385.sce8081	2.57e-322	995.0	COG0143@1|root,COG0143@2|Bacteria,1MUBY@1224|Proteobacteria,42ZB0@68525|delta/epsilon subdivisions,2WUQM@28221|Deltaproteobacteria,2Z2YN@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
SHD3_k127_1741477_3	502025.Hoch_5411	2.343e-37	146.0	COG0647@1|root,COG0647@2|Bacteria	2|Bacteria	G	UMP catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SHD3_k127_1746831_0	448385.sce0648	3.31e-24	109.0	COG2885@1|root,COG2885@2|Bacteria,1QAG8@1224|Proteobacteria,4352E@68525|delta/epsilon subdivisions,2WZDB@28221|Deltaproteobacteria,2Z1W3@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SHD3_k127_1746831_2	1144275.COCOR_00165	5.359e-07	62.0	COG1538@1|root,COG1538@2|Bacteria,1PDKT@1224|Proteobacteria,4398W@68525|delta/epsilon subdivisions,2X4G7@28221|Deltaproteobacteria,2YYYH@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SHD3_k127_1746831_3	1242864.D187_002495	6.105e-05	54.0	2EIZM@1|root,33CQT@2|Bacteria,1P1YR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1746831_1	330214.NIDE0303	7.659e-15	81.0	COG0265@1|root,COG0265@2|Bacteria,3J0X9@40117|Nitrospirae	2|Bacteria	M	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	htrA	GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SHD3_k127_1757619_9	903818.KI912268_gene3221	1.639e-32	137.0	COG2270@1|root,COG2270@2|Bacteria,3Y9EJ@57723|Acidobacteria	57723|Acidobacteria	S	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SHD3_k127_1757619_3	1340493.JNIF01000003_gene4182	3.214e-86	291.0	COG1028@1|root,COG1028@2|Bacteria	1340493.JNIF01000003_gene4182|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1757619_6	644282.Deba_2688	1.058e-64	246.0	COG0745@1|root,COG2202@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_1757619_11	1399115.U719_00850	6.351e-28	126.0	COG1160@1|root,COG3597@1|root,COG1160@2|Bacteria,COG3597@2|Bacteria,1TSZW@1239|Firmicutes,4HCAY@91061|Bacilli	91061|Bacilli	S	Domain of unknown function (DUF697)	-	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	DUF697,MMR_HSR1
SHD3_k127_1757619_12	1042156.CXIVA_08470	2.265e-13	78.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,36JV0@31979|Clostridiaceae	186801|Clostridia	I	Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
SHD3_k127_1757619_0	886293.Sinac_5112	5.447e-165	527.0	COG0686@1|root,COG0686@2|Bacteria,2IXPP@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the AlaDH PNT family	-	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SHD3_k127_1757619_10	1254432.SCE1572_40935	5.453e-31	129.0	COG2204@1|root,COG2204@2|Bacteria,1NABF@1224|Proteobacteria,43C0I@68525|delta/epsilon subdivisions,2X7B5@28221|Deltaproteobacteria,2Z3KD@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_1757619_1	247490.KSU1_C0538	1.123e-141	456.0	COG1741@1|root,COG1741@2|Bacteria,2IXVU@203682|Planctomycetes	203682|Planctomycetes	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
SHD3_k127_1757619_7	1254432.SCE1572_13980	6.419e-59	212.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_1757619_5	706587.Desti_2256	5.99e-66	232.0	COG3945@1|root,COG3945@2|Bacteria,1NX3S@1224|Proteobacteria,430RH@68525|delta/epsilon subdivisions,2WVY3@28221|Deltaproteobacteria,2MS02@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SHD3_k127_1757619_4	767817.Desgi_2411	9.376e-82	280.0	COG0491@1|root,COG0491@2|Bacteria,1V2XF@1239|Firmicutes,24JW4@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SHD3_k127_1757619_14	272942.RCAP_rcc02367	0.0002215	51.0	2DRGX@1|root,33BPS@2|Bacteria,1Q9CQ@1224|Proteobacteria,2VBIK@28211|Alphaproteobacteria,1FC6I@1060|Rhodobacter	28211|Alphaproteobacteria	S	EF hand	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
SHD3_k127_1757619_8	1254432.SCE1572_50250	3.209e-44	166.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,43DXP@68525|delta/epsilon subdivisions,2X910@28221|Deltaproteobacteria,2Z1D7@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_1757619_13	448385.sce8791	6.128e-05	51.0	2AGZU@1|root,3178K@2|Bacteria,1PYIG@1224|Proteobacteria,43E50@68525|delta/epsilon subdivisions,2WZR6@28221|Deltaproteobacteria,2Z2JU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_176714_2	237368.SCABRO_00917	1.364e-64	239.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_176714_1	671143.DAMO_0934	1.733e-75	267.0	COG0300@1|root,COG0300@2|Bacteria	2|Bacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	ymfI	-	1.1.1.100,1.3.1.28	ko:K00059,ko:K00216,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	M00083,M00572	R01505,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117,RC00534	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
SHD3_k127_176714_0	1192034.CAP_7446	4.132e-87	301.0	COG0392@1|root,COG0392@2|Bacteria,1PPSZ@1224|Proteobacteria,434R6@68525|delta/epsilon subdivisions,2WZ2B@28221|Deltaproteobacteria,2Z16A@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SHD3_k127_176714_3	1380394.JADL01000003_gene5229	1.484e-08	57.0	COG0673@1|root,COG0673@2|Bacteria,1MUZI@1224|Proteobacteria,2U21V@28211|Alphaproteobacteria,2JXPB@204441|Rhodospirillales	204441|Rhodospirillales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.292	ko:K19181	-	-	-	-	ko00000,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SHD3_k127_1783623_3	1452718.JBOY01000054_gene1972	1.05e-117	387.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,1RND3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SHD3_k127_1783623_5	1121124.JNIX01000013_gene1400	4.141e-61	213.0	COG0346@1|root,COG0346@2|Bacteria,1RCYX@1224|Proteobacteria,2U7A8@28211|Alphaproteobacteria,2KGHS@204458|Caulobacterales	204458|Caulobacterales	E	Glyoxalase bleomycin resistance protein dioxygenase	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
SHD3_k127_1783623_0	448385.sce7663	1.554e-220	692.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SHD3_k127_1783623_6	1379698.RBG1_1C00001G1240	8.566e-61	226.0	COG2239@1|root,COG2239@2|Bacteria,2NP79@2323|unclassified Bacteria	2|Bacteria	P	MgtE intracellular N domain	opuCA	-	3.6.3.32	ko:K02000,ko:K05847	ko02010,map02010	M00208,M00209	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.12	-	iSB619.SA_RS12845	ABC_tran,CBS,MgtE_N,PRC
SHD3_k127_1783623_1	1399774.JDWH01000030_gene2329	3.351e-153	496.0	COG1914@1|root,COG1914@2|Bacteria,1N0XH@1224|Proteobacteria,1SMEC@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	Natural resistance-associated macrophage protein	-	-	-	-	-	-	-	-	-	-	-	-	Nramp
SHD3_k127_1783623_4	1254432.SCE1572_12410	7.626e-79	273.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria,2YUU1@29|Myxococcales	28221|Deltaproteobacteria	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
SHD3_k127_1783623_2	1254432.SCE1572_12415	8.102e-141	463.0	COG1641@1|root,COG1641@2|Bacteria,1MUKU@1224|Proteobacteria,42MHQ@68525|delta/epsilon subdivisions,2WJAC@28221|Deltaproteobacteria,2YUS7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LarC family	-	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
SHD3_k127_1783623_8	1121920.AUAU01000007_gene404	7.051e-10	59.0	COG0334@1|root,COG0334@2|Bacteria	2|Bacteria	E	glutamate dehydrogenase [NAD(P)+] activity	gdh	GO:0005575,GO:0005623,GO:0009986,GO:0044464	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
SHD3_k127_1796864_1	247634.GPB2148_2650	3.385e-08	57.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Glyco_hydro_17,MFS_2
SHD3_k127_1796864_0	391625.PPSIR1_19764	3.696e-13	79.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
SHD3_k127_1812859_5	404589.Anae109_0915	1.5e-34	141.0	COG2197@1|root,COG2197@2|Bacteria,1NCBR@1224|Proteobacteria,433WZ@68525|delta/epsilon subdivisions,2X3XU@28221|Deltaproteobacteria,2YXHT@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SHD3_k127_1812859_2	404589.Anae109_0913	3.606e-47	182.0	COG0265@1|root,COG0265@2|Bacteria,1N1NJ@1224|Proteobacteria	1224|Proteobacteria	O	PDZ DHR GLGF domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_1812859_0	1297742.A176_07212	1.068e-78	277.0	COG0265@1|root,COG0265@2|Bacteria,1N58P@1224|Proteobacteria	1224|Proteobacteria	O	peptidase S1 and S6 chymotrypsin Hap	MA20_17565	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_1812859_1	357808.RoseRS_2309	7.08e-73	263.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1812859_3	1254432.SCE1572_33835	7.167e-36	151.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SHD3_k127_1812859_7	1185876.BN8_04779	1.123e-05	58.0	COG3170@1|root,COG3170@2|Bacteria,4NIBX@976|Bacteroidetes,47JCB@768503|Cytophagia	976|Bacteroidetes	NU	Astacin (Peptidase family M12A)	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
SHD3_k127_1812859_4	102125.Xen7305DRAFT_00051590	6.187e-35	151.0	COG1957@1|root,COG2730@1|root,COG1957@2|Bacteria,COG2730@2|Bacteria,1GA5Y@1117|Cyanobacteria,3VK82@52604|Pleurocapsales	1117|Cyanobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Cellulase,DUF4114
SHD3_k127_1812859_6	3055.EDP05543	8.472e-07	51.0	KOG1225@1|root,KOG1225@2759|Eukaryota,380A0@33090|Viridiplantae	33090|Viridiplantae	O	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1818474_0	1254432.SCE1572_30460	2.464e-117	419.0	COG3568@1|root,COG3568@2|Bacteria,1PG5A@1224|Proteobacteria,43E4I@68525|delta/epsilon subdivisions,2WZPU@28221|Deltaproteobacteria,2Z2HE@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1818474_1	1500897.JQNA01000002_gene4399	7.157e-22	107.0	28IH6@1|root,2Z8IF@2|Bacteria,1R4Z0@1224|Proteobacteria,2VRWN@28216|Betaproteobacteria,1K2UT@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1822754_4	118005.AWNK01000005_gene1540	9.589e-55	200.0	COG0785@1|root,COG0785@2|Bacteria	2|Bacteria	O	Cytochrome C biogenesis protein	ccdA	-	1.8.4.11,1.8.4.12	ko:K06196,ko:K12267	-	-	-	-	ko00000,ko01000,ko02000	5.A.1.2	-	-	AhpC-TSA,DsbD
SHD3_k127_1822754_2	1459636.NTE_03291	1.297e-74	262.0	arCOG03562@1|root,arCOG03562@2157|Archaea,41SY7@651137|Thaumarchaeota	651137|Thaumarchaeota	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SHD3_k127_1822754_1	1229780.BN381_250054	9.934e-167	554.0	COG0383@1|root,COG0383@2|Bacteria	2|Bacteria	G	mannose metabolic process	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
SHD3_k127_1822754_0	1192034.CAP_5722	1.212e-182	598.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,2YTU8@29|Myxococcales	28221|Deltaproteobacteria	D	protein involved in exopolysaccharide biosynthesis	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
SHD3_k127_1822754_3	1144275.COCOR_01774	4.026e-68	247.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
SHD3_k127_1822754_6	497964.CfE428DRAFT_1503	6.202e-12	75.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2,START
SHD3_k127_1822754_5	744980.TRICHSKD4_3738	4.576e-54	203.0	COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,2TV1Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	MA20_30275	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
SHD3_k127_1824310_10	448385.sce3838	1.888e-42	169.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2Z1RM@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1824310_12	448385.sce3837	6.219e-22	98.0	2AIXI@1|root,319F6@2|Bacteria,1Q2J0@1224|Proteobacteria,4385U@68525|delta/epsilon subdivisions,2X3FN@28221|Deltaproteobacteria,2YVWG@29|Myxococcales	28221|Deltaproteobacteria	S	Ribbon-helix-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	RHH_3
SHD3_k127_1824310_2	1254432.SCE1572_23010	1.982e-159	514.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42N0H@68525|delta/epsilon subdivisions,2WK9P@28221|Deltaproteobacteria,2YU0X@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_1824310_6	1254432.SCE1572_23005	1.859e-121	409.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,42M74@68525|delta/epsilon subdivisions,2WR3G@28221|Deltaproteobacteria,2YXS5@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_1824310_0	765911.Thivi_3764	7.167e-244	766.0	COG1523@1|root,COG1523@2|Bacteria,1R7FD@1224|Proteobacteria	1224|Proteobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SHD3_k127_1824310_3	483219.LILAB_36060	1.852e-143	475.0	COG1109@1|root,COG1109@2|Bacteria,1QUGD@1224|Proteobacteria,43BUU@68525|delta/epsilon subdivisions,2WKYP@28221|Deltaproteobacteria,2YTV9@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SHD3_k127_1824310_5	1254432.SCE1572_28850	8.759e-122	401.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YURZ@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
SHD3_k127_1824310_7	1254432.SCE1572_28640	1.62e-110	365.0	COG1694@1|root,COG3956@2|Bacteria,1MVKM@1224|Proteobacteria,42R48@68525|delta/epsilon subdivisions,2WMAR@28221|Deltaproteobacteria,2YUR9@29|Myxococcales	28221|Deltaproteobacteria	E	MazG nucleotide pyrophosphohydrolase domain	mazG	-	3.6.1.9	ko:K02499,ko:K04765	ko00230,ko00240,ko00760,ko00770,ko01100,map00230,map00240,map00760,map00770,map01100	-	R00086,R00087,R00103,R00287,R00426,R00515,R00662,R00720,R03004,R03036,R11323	RC00002	ko00000,ko00001,ko01000,ko03036	-	-	-	MazG
SHD3_k127_1824310_9	1254432.SCE1572_37335	9.799e-52	199.0	COG0354@1|root,COG0354@2|Bacteria,1QYGE@1224|Proteobacteria,43CCJ@68525|delta/epsilon subdivisions,2WYDB@28221|Deltaproteobacteria,2Z3H2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
SHD3_k127_1824310_8	1192034.CAP_0054	2.866e-58	213.0	COG0793@1|root,COG5038@1|root,COG0793@2|Bacteria,COG5038@2|Bacteria	2|Bacteria	M	C2 domain	-	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	C2,CarboxypepD_reg,PDZ,PDZ_2,Peptidase_S41
SHD3_k127_1824310_11	1192034.CAP_0051	3.853e-24	111.0	COG5567@1|root,COG5567@2|Bacteria	2|Bacteria	N	small periplasmic lipoprotein	yifL	-	-	-	-	-	-	-	-	-	-	-	LPAM_2
SHD3_k127_1824310_4	518766.Rmar_2616	4.513e-139	466.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1FIS9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_1824310_1	1191523.MROS_1644	3.391e-242	778.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	xylS	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31,PA14
SHD3_k127_1824310_13	1254432.SCE1572_41815	2.692e-12	75.0	2A3H8@1|root,30S02@2|Bacteria,1PD5P@1224|Proteobacteria,43E5D@68525|delta/epsilon subdivisions,2WZS5@28221|Deltaproteobacteria,2Z2MN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_183124_12	32057.KB217478_gene697	3.864e-05	50.0	COG0457@1|root,COG1357@1|root,COG0457@2|Bacteria,COG1357@2|Bacteria,1GIT3@1117|Cyanobacteria,1HMM6@1161|Nostocales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,TPR_1,TPR_11,TPR_16,TPR_8
SHD3_k127_183124_2	1210884.HG799462_gene9086	3.639e-102	355.0	COG4191@1|root,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_183124_6	1254432.SCE1572_18315	6.255e-90	312.0	COG0318@1|root,COG0318@2|Bacteria,1MW0Y@1224|Proteobacteria,42SEI@68525|delta/epsilon subdivisions,2WPEN@28221|Deltaproteobacteria,2YY7E@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	menE	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
SHD3_k127_183124_9	502025.Hoch_5719	2.36e-51	196.0	COG4948@1|root,COG4948@2|Bacteria,1MU8R@1224|Proteobacteria,42WKH@68525|delta/epsilon subdivisions,2WSGE@28221|Deltaproteobacteria,2YVQV@29|Myxococcales	28221|Deltaproteobacteria	H	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
SHD3_k127_183124_3	448385.sce3013	2.15e-95	324.0	COG1575@1|root,COG1575@2|Bacteria,1MXQQ@1224|Proteobacteria,42S34@68525|delta/epsilon subdivisions,2X5AY@28221|Deltaproteobacteria,2Z34Z@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SHD3_k127_183124_1	987059.RBXJA2T_13966	9.399e-147	473.0	COG0447@1|root,COG0447@2|Bacteria,1QTZ2@1224|Proteobacteria,2VJ36@28216|Betaproteobacteria,1KKKJ@119065|unclassified Burkholderiales	28216|Betaproteobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	-	4.1.3.36	ko:K01661,ko:K07536	ko00130,ko00362,ko01100,ko01110,ko01120,ko01220,map00130,map00362,map01100,map01110,map01120,map01220	M00116,M00540	R05592,R07263	RC01429,RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
SHD3_k127_183124_5	1254432.SCE1572_18295	1.88e-93	325.0	COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,42PNC@68525|delta/epsilon subdivisions,2WKSZ@28221|Deltaproteobacteria,2YUJF@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SHD3_k127_183124_11	522306.CAP2UW1_1909	5.079e-19	93.0	COG1165@1|root,COG1165@2|Bacteria,1MVMZ@1224|Proteobacteria,2VNGG@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M_2,TPP_enzyme_N
SHD3_k127_183124_7	502025.Hoch_5716	2.303e-78	285.0	COG1169@1|root,COG1169@2|Bacteria,1MVB7@1224|Proteobacteria,42S21@68525|delta/epsilon subdivisions,2WNRS@28221|Deltaproteobacteria,2YV7S@29|Myxococcales	28221|Deltaproteobacteria	HQ	chorismate binding enzyme	menF	-	5.4.4.2	ko:K01851,ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
SHD3_k127_183124_8	502025.Hoch_5715	1.591e-70	254.0	COG0500@1|root,COG2226@2|Bacteria,1MX8I@1224|Proteobacteria,42P2Z@68525|delta/epsilon subdivisions,2WNJ6@28221|Deltaproteobacteria,2YU8C@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)	ubiE	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
SHD3_k127_183124_10	502025.Hoch_5901	6.259e-41	161.0	COG1510@1|root,COG1510@2|Bacteria,1RA49@1224|Proteobacteria,432MH@68525|delta/epsilon subdivisions,2WYFU@28221|Deltaproteobacteria,2YVDK@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the GbsR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SHD3_k127_183124_4	1122222.AXWR01000022_gene321	1.519e-94	326.0	COG0493@1|root,COG0493@2|Bacteria,1WKX0@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	COG0493 NADPH-dependent glutamate synthase beta chain and related	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	NAD_binding_9,Pyr_redox_2
SHD3_k127_183124_0	314230.DSM3645_04065	1.124e-216	693.0	COG0210@1|root,COG0210@2|Bacteria,2IWT0@203682|Planctomycetes	203682|Planctomycetes	L	COG0210 Superfamily I DNA and RNA	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SHD3_k127_1852402_0	391625.PPSIR1_12308	5.19e-48	189.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SHD3_k127_1852402_2	1121899.Q764_07620	9.64e-15	88.0	COG3291@1|root,COG3291@2|Bacteria,4PKMZ@976|Bacteroidetes,1I9DA@117743|Flavobacteriia,2P0DU@237|Flavobacterium	976|Bacteroidetes	S	TIGRFAM Por secretion system C-terminal sorting domain	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C
SHD3_k127_1852402_1	502025.Hoch_2959	2.352e-22	100.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SHD3_k127_1853342_8	1254432.SCE1572_08070	4.668e-34	140.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_1853342_4	1254432.SCE1572_08075	1.456e-76	273.0	COG1729@1|root,COG3712@1|root,COG1729@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_6,WG_beta_rep
SHD3_k127_1853342_1	448385.sce4100	1.3e-117	387.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria	1224|Proteobacteria	Q	Poly3-Hydroxybutyrate Depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase,Esterase_phd
SHD3_k127_1853342_2	1254432.SCE1572_09790	5.636e-101	343.0	COG1506@1|root,COG1506@2|Bacteria,1R0PB@1224|Proteobacteria	1224|Proteobacteria	E	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1853342_5	1869.MB27_01580	2.754e-75	265.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4DI53@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 12 (cellulase H) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12
SHD3_k127_1853342_3	760192.Halhy_3096	7.894e-91	325.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,1IZUU@117747|Sphingobacteriia	976|Bacteroidetes	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
SHD3_k127_1853342_9	383372.Rcas_0264	4.119e-18	98.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1853342_0	1009370.ALO_10784	4.039e-158	510.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4H2MY@909932|Negativicutes	909932|Negativicutes	P	Transporter major facilitator family protein	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
SHD3_k127_1853342_6	1267533.KB906741_gene534	1.658e-66	231.0	COG1247@1|root,COG1247@2|Bacteria,3Y8PE@57723|Acidobacteria,2JNS4@204432|Acidobacteriia	204432|Acidobacteriia	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
SHD3_k127_1853342_10	63577.G9NNW8	1.289e-12	68.0	28JQD@1|root,2QS3Q@2759|Eukaryota,38HXY@33154|Opisthokonta,3NY8Q@4751|Fungi,3QJBJ@4890|Ascomycota,213VW@147550|Sordariomycetes,3TJRS@5125|Hypocreales,3TX67@5129|Hypocreaceae	4751|Fungi	G	Alpha-L-arabinofuranosidase B (ABFB) domain	abfB	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005975,GO:0005976,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010393,GO:0016052,GO:0016787,GO:0016798,GO:0017144,GO:0019321,GO:0019566,GO:0031221,GO:0042737,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044464,GO:0045488,GO:0045490,GO:0046556,GO:0071704,GO:1901575	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	AbfB,ArabFuran-catal
SHD3_k127_1855187_8	1254432.SCE1572_10655	4.781e-35	143.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	surA	-	5.2.1.8	ko:K02597,ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
SHD3_k127_1855187_5	448385.sce1699	1.406e-55	205.0	COG0571@1|root,COG0571@2|Bacteria,1MUQ6@1224|Proteobacteria,42MIP@68525|delta/epsilon subdivisions,2WNDB@28221|Deltaproteobacteria,2YVFW@29|Myxococcales	28221|Deltaproteobacteria	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
SHD3_k127_1855187_2	1254432.SCE1572_10685	1.704e-105	355.0	2ABSM@1|root,31194@2|Bacteria,1RDYC@1224|Proteobacteria,432T5@68525|delta/epsilon subdivisions,2WY30@28221|Deltaproteobacteria,2YVSJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1855187_4	1192034.CAP_7796	6.927e-56	200.0	COG0219@1|root,COG0219@2|Bacteria,1RCY4@1224|Proteobacteria,42RJX@68525|delta/epsilon subdivisions,2WQNR@28221|Deltaproteobacteria,2YZSU@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SHD3_k127_1855187_3	1192034.CAP_6318	3.237e-84	300.0	COG0484@1|root,COG2206@1|root,COG0484@2|Bacteria,COG2206@2|Bacteria,1QX6J@1224|Proteobacteria,43BZ5@68525|delta/epsilon subdivisions,2X79W@28221|Deltaproteobacteria,2Z3EH@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SHD3_k127_1855187_0	448385.sce1691	4.222e-202	638.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YUPC@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	crdA	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_1855187_9	690850.Desaf_1754	5.628e-29	122.0	COG2337@1|root,COG2337@2|Bacteria,1MYU1@1224|Proteobacteria,42UNN@68525|delta/epsilon subdivisions,2WQA2@28221|Deltaproteobacteria,2MFFM@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SHD3_k127_1855187_11	1469607.KK073769_gene6107	7.313e-09	64.0	COG0864@1|root,COG0864@2|Bacteria,1G9E4@1117|Cyanobacteria,1HPW8@1161|Nostocales	1117|Cyanobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1855187_1	404589.Anae109_2802	8.754e-121	406.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_1862925_9	1297742.A176_00947	2.132e-64	225.0	COG4636@1|root,COG4636@2|Bacteria,1RCFH@1224|Proteobacteria,43ACW@68525|delta/epsilon subdivisions,2X5SW@28221|Deltaproteobacteria,2YZYB@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_1862925_0	1192034.CAP_8959	0.0	1234.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YU3Z@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon-2	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SHD3_k127_1862925_1	1254432.SCE1572_19005	2.425e-239	743.0	COG1219@1|root,COG1219@2|Bacteria,1MVQK@1224|Proteobacteria,42MWJ@68525|delta/epsilon subdivisions,2WJ8Q@28221|Deltaproteobacteria,2YUHC@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
SHD3_k127_1862925_6	1192034.CAP_8961	3.7e-96	320.0	COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,42MFU@68525|delta/epsilon subdivisions,2WK74@28221|Deltaproteobacteria,2YUR2@29|Myxococcales	28221|Deltaproteobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
SHD3_k127_1862925_5	448385.sce3146	9.834e-123	409.0	COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,42MBB@68525|delta/epsilon subdivisions,2WIU1@28221|Deltaproteobacteria,2YV7J@29|Myxococcales	28221|Deltaproteobacteria	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
SHD3_k127_1862925_8	1110502.TMO_3418	4.911e-77	270.0	COG1192@1|root,COG1192@2|Bacteria,1MV43@1224|Proteobacteria,2TSWH@28211|Alphaproteobacteria,2JQ3M@204441|Rhodospirillales	204441|Rhodospirillales	D	Chromosome partitioning	parA	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
SHD3_k127_1862925_7	1192034.CAP_8966	2.379e-91	318.0	COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,42M8S@68525|delta/epsilon subdivisions,2WNG8@28221|Deltaproteobacteria,2YV3C@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the ParB family	parB	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SHD3_k127_1862925_4	243231.GSU0247	4.205e-148	483.0	COG1032@1|root,COG1032@2|Bacteria,1RCWX@1224|Proteobacteria,43AIJ@68525|delta/epsilon subdivisions,2X5YS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_1862925_3	555088.DealDRAFT_2165	4.35e-176	575.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,42JHA@68298|Syntrophomonadaceae	186801|Clostridia	J	elongation factor Tu domain 2 protein	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
SHD3_k127_1862925_2	452662.SJA_C2-02340	4.48e-186	591.0	COG0657@1|root,COG0657@2|Bacteria,1QDQP@1224|Proteobacteria,2U41U@28211|Alphaproteobacteria,2K2PZ@204457|Sphingomonadales	204457|Sphingomonadales	I	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
SHD3_k127_1865085_2	448385.sce4378	2.878e-16	83.0	COG0597@1|root,COG0597@2|Bacteria	2|Bacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
SHD3_k127_1865085_3	398527.Bphyt_4399	0.0007889	49.0	2EHMJ@1|root,33BDB@2|Bacteria,1RG1S@1224|Proteobacteria,2W287@28216|Betaproteobacteria,1K3X0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Domain of unknown function (DUF4410)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4410
SHD3_k127_1865085_1	1541960.KQ78_00682	3.275e-18	97.0	2BDA6@1|root,326YM@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	-
SHD3_k127_1865085_0	1042209.HK44_019320	1.253e-27	118.0	COG0599@1|root,COG0599@2|Bacteria,1RK66@1224|Proteobacteria,1RV3Y@1236|Gammaproteobacteria,1YTA3@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
SHD3_k127_188050_0	290397.Adeh_3883	1.016e-67	259.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2Z1PP@29|Myxococcales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM,TPR_14,TPR_16
SHD3_k127_1880891_4	1321778.HMPREF1982_01729	2.478e-09	64.0	COG0477@1|root,COG2814@2|Bacteria,1TQDU@1239|Firmicutes,25ESY@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SHD3_k127_1880891_1	448385.sce4543	5.2e-105	370.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,43ARV@68525|delta/epsilon subdivisions,2X65Y@28221|Deltaproteobacteria,2Z39J@29|Myxococcales	448385.sce4543|-	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SHD3_k127_1880891_2	448385.sce6431	6.817e-75	260.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria,2YXSM@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SHD3_k127_1880891_3	1254432.SCE1572_01035	4.173e-33	132.0	2AN6E@1|root,31D4B@2|Bacteria,1QA73@1224|Proteobacteria,434VH@68525|delta/epsilon subdivisions,2X91G@28221|Deltaproteobacteria,2Z1FK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1880891_0	377629.TERTU_1599	2.825e-231	756.0	COG3693@1|root,COG3693@2|Bacteria,1R7BZ@1224|Proteobacteria,1S17S@1236|Gammaproteobacteria,2PQ0G@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,CBM_6,Glyco_hydro_10
SHD3_k127_1889174_5	1408310.JHUW01000012_gene670	1.818e-26	120.0	29FVP@1|root,302TD@2|Bacteria,4NQ1K@976|Bacteroidetes,2FVI8@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4380
SHD3_k127_1889174_4	1396141.BATP01000023_gene685	5.327e-47	182.0	COG1913@1|root,COG1913@2|Bacteria,46WX0@74201|Verrucomicrobia,2IVPQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Peptidase family M54	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M54
SHD3_k127_1889174_3	755731.Clo1100_1820	2.167e-58	225.0	COG3405@1|root,COG3405@2|Bacteria,1VARG@1239|Firmicutes,24BG1@186801|Clostridia,36VIA@31979|Clostridiaceae	186801|Clostridia	G	Glycosyl hydrolases family 8	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Glyco_hydro_8
SHD3_k127_1889174_0	1254432.SCE1572_17685	0.0	1060.0	COG0515@1|root,COG2203@1|root,COG3829@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YTVN@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,GAF_2,HTH_8,Pkinase,PocR,Sigma54_activat
SHD3_k127_1889174_1	589865.DaAHT2_2572	4.655e-124	408.0	COG0116@1|root,COG0116@2|Bacteria,1MUQM@1224|Proteobacteria,42NJ1@68525|delta/epsilon subdivisions,2WJ5S@28221|Deltaproteobacteria,2MIZQ@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Belongs to the methyltransferase superfamily	rlmL	-	2.1.1.173,2.1.1.264	ko:K07444,ko:K12297	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,THUMP,UPF0020
SHD3_k127_1889174_2	903818.KI912268_gene2579	2.494e-74	258.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4,Glycos_transf_2
SHD3_k127_1899469_0	290397.Adeh_4227	4.887e-50	184.0	COG1392@1|root,COG1392@2|Bacteria,1R4SP@1224|Proteobacteria,42SPV@68525|delta/epsilon subdivisions,2WPTH@28221|Deltaproteobacteria,2Z0HM@29|Myxococcales	28221|Deltaproteobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
SHD3_k127_1906358_3	1267535.KB906767_gene1907	1.235e-85	285.0	COG0693@1|root,COG0693@2|Bacteria,3Y5M0@57723|Acidobacteria	57723|Acidobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SHD3_k127_1906358_2	35754.JNYJ01000011_gene662	6.377e-93	311.0	COG1028@1|root,COG1028@2|Bacteria,2GP1K@201174|Actinobacteria,4DHPW@85008|Micromonosporales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SHD3_k127_1906358_8	1461694.ATO9_09650	8.954e-31	128.0	2DMP1@1|root,32SS8@2|Bacteria,1MZTD@1224|Proteobacteria,2U86W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
SHD3_k127_1906358_7	1408164.MOLA814_01668	2.536e-44	166.0	2DMP1@1|root,32SS8@2|Bacteria,1MZTD@1224|Proteobacteria,2WG6B@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
SHD3_k127_1906358_12	1184267.A11Q_2465	9.497e-12	77.0	28V2A@1|root,2ZH5S@2|Bacteria,1P7QH@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
SHD3_k127_1906358_15	448385.sce3700	0.0001078	53.0	29Z4I@1|root,30M26@2|Bacteria,1QAWT@1224|Proteobacteria,435CA@68525|delta/epsilon subdivisions,2WZPW@28221|Deltaproteobacteria,2Z2HH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1906358_9	1146883.BLASA_1069	1.378e-21	102.0	COG1595@1|root,COG1595@2|Bacteria,2IHWH@201174|Actinobacteria,4EVQ8@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase sigma factor	sigC	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_1906358_13	114615.BRADO6480	1.628e-07	63.0	292R0@1|root,2ZQ8S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1906358_10	502025.Hoch_2959	4.998e-16	82.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SHD3_k127_1906358_11	1110697.NCAST_20_01160	3.075e-15	89.0	COG1397@1|root,COG1397@2|Bacteria,2HSBE@201174|Actinobacteria,4FZPT@85025|Nocardiaceae	201174|Actinobacteria	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1906358_6	1144275.COCOR_01187	3.294e-56	217.0	COG3279@1|root,COG3279@2|Bacteria,1MVJI@1224|Proteobacteria,43ADC@68525|delta/epsilon subdivisions,2X5T8@28221|Deltaproteobacteria,2Z38R@29|Myxococcales	28221|Deltaproteobacteria	K	LytTr DNA-binding domain	lytT	-	-	ko:K02477,ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
SHD3_k127_1906358_5	215803.DB30_2687	5.113e-75	263.0	COG2972@1|root,COG2972@2|Bacteria,1MXVQ@1224|Proteobacteria,42R4U@68525|delta/epsilon subdivisions,2X799@28221|Deltaproteobacteria,2YZAA@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K08082	ko02020,map02020	M00493	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
SHD3_k127_1906358_1	1267533.KB906733_gene3195	6.359e-127	412.0	COG0702@1|root,COG0702@2|Bacteria,3Y3QX@57723|Acidobacteria,2JJ6V@204432|Acidobacteriia	204432|Acidobacteriia	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SHD3_k127_1906358_0	639030.JHVA01000001_gene3700	1.67e-156	497.0	COG2267@1|root,COG2267@2|Bacteria,3Y46X@57723|Acidobacteria,2JHJ7@204432|Acidobacteriia	204432|Acidobacteriia	I	Serine aminopeptidase, S33	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
SHD3_k127_1906358_14	404589.Anae109_2797	8.218e-06	53.0	COG4974@1|root,COG4974@2|Bacteria,1Q4H1@1224|Proteobacteria,43A00@68525|delta/epsilon subdivisions,2X29E@28221|Deltaproteobacteria,2YZ6M@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SHD3_k127_1906358_4	566466.NOR53_2559	1.681e-84	301.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1RSDY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
SHD3_k127_1914577_1	357808.RoseRS_0421	1.644e-88	315.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_1914577_5	543632.JOJL01000006_gene9563	1.169e-14	80.0	2BEQE@1|root,328G0@2|Bacteria,2HE8X@201174|Actinobacteria,4DKTW@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1914577_0	326427.Cagg_0669	1.525e-95	340.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1914577_7	1089550.ATTH01000001_gene707	1.604e-13	83.0	COG3291@1|root,COG3291@2|Bacteria,4PHV2@976|Bacteroidetes,1FJZR@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1914577_2	518766.Rmar_0025	7.404e-30	136.0	COG2730@1|root,COG2730@2|Bacteria,4NIBG@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
SHD3_k127_1914577_3	1680.BADO_1512	8.904e-30	136.0	COG2273@1|root,COG3533@1|root,COG3757@1|root,COG2273@2|Bacteria,COG3533@2|Bacteria,COG3757@2|Bacteria,2I2GQ@201174|Actinobacteria,4D08Z@85004|Bifidobacteriales	201174|Actinobacteria	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_25,RicinB_lectin_2,SLH
SHD3_k127_1914577_6	706587.Desti_0850	1.002e-13	76.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIU5@28221|Deltaproteobacteria,2MQZQ@213462|Syntrophobacterales	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_1914577_4	1045858.Bint_2859	7.758e-16	83.0	COG4640@1|root,COG4640@2|Bacteria	2|Bacteria	KT	response to antibiotic	-	-	-	-	-	-	-	-	-	-	-	-	CD225,DUF4234,DUF4339,zinc_ribbon_2
SHD3_k127_1920458_2	391625.PPSIR1_11130	9.965e-54	205.0	COG1262@1|root,COG1262@2|Bacteria,1QADB@1224|Proteobacteria,43503@68525|delta/epsilon subdivisions,2X93Q@28221|Deltaproteobacteria,2Z1R3@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_1920458_3	370438.PTH_0467	1.712e-33	137.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia,26152@186807|Peptococcaceae	186801|Clostridia	S	pfam ammecr1	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
SHD3_k127_1920458_1	1254432.SCE1572_36110	2.035e-103	345.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WKFE@28221|Deltaproteobacteria,2YUTV@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SHD3_k127_1920458_0	502025.Hoch_2100	0.0	1210.0	COG4770@1|root,COG4799@1|root,COG4770@2|Bacteria,COG4799@2|Bacteria,1P6RE@1224|Proteobacteria,43A2M@68525|delta/epsilon subdivisions,2X1XW@28221|Deltaproteobacteria,2YX2T@29|Myxococcales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase, central region	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
SHD3_k127_1926081_0	351607.Acel_0616	3.732e-113	383.0	COG3934@1|root,COG3934@2|Bacteria,2IC0X@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	Cellulase
SHD3_k127_192712_2	157072.XP_008861966.1	1.813e-07	63.0	2CYVY@1|root,2S6T0@2759|Eukaryota	2759|Eukaryota	S	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_192712_0	448385.sce1766	1.453e-262	839.0	COG1391@1|root,COG1391@2|Bacteria,1MU4I@1224|Proteobacteria,42MCT@68525|delta/epsilon subdivisions,2WINW@28221|Deltaproteobacteria,2YU71@29|Myxococcales	28221|Deltaproteobacteria	H	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	-	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
SHD3_k127_192712_1	448385.sce1765	5.816e-54	193.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SHD3_k127_1941507_1	1444712.BN1013_00669	1.521e-122	416.0	COG0306@1|root,COG0306@2|Bacteria,2JH20@204428|Chlamydiae	204428|Chlamydiae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SHD3_k127_1941507_2	1254432.SCE1572_17910	3.194e-66	233.0	COG0704@1|root,COG0704@2|Bacteria,1MUMI@1224|Proteobacteria,42QWG@68525|delta/epsilon subdivisions,2WN1U@28221|Deltaproteobacteria,2Z2Z8@29|Myxococcales	28221|Deltaproteobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
SHD3_k127_1941507_0	1192034.CAP_6022	1.257e-309	974.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria,2YYGK@29|Myxococcales	28221|Deltaproteobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SHD3_k127_1946028_1	1296415.JACC01000014_gene967	8.542e-09	70.0	COG3227@1|root,COG4733@1|root,COG3227@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	3.4.24.28	ko:K01400	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	FTP,MAM,PepSY,Peptidase_M4,Peptidase_M4_C,Peptidase_S8,fn3
SHD3_k127_1946028_0	469383.Cwoe_0404	3.028e-15	91.0	COG1361@1|root,COG1520@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,2HQK8@201174|Actinobacteria,4CQWH@84995|Rubrobacteria	84995|Rubrobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1957484_1	404589.Anae109_1771	5.744e-71	262.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PDY@68525|delta/epsilon subdivisions,2WUVK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SHD3_k127_1957484_0	448385.sce4178	2.898e-136	442.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Chlorophyllase2,Esterase
SHD3_k127_1958041_3	794903.OPIT5_08550	5.802e-06	53.0	COG0451@1|root,COG0451@2|Bacteria,46VB4@74201|Verrucomicrobia,3K9ME@414999|Opitutae	414999|Opitutae	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SHD3_k127_1958041_0	448385.sce0180	6.082e-221	706.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42M01@68525|delta/epsilon subdivisions,2X1Y5@28221|Deltaproteobacteria,2YWWG@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SHD3_k127_1958041_2	4572.TRIUR3_16644-P1	2.91e-09	61.0	2EXND@1|root,2SZA1@2759|Eukaryota,381T7@33090|Viridiplantae	4572.TRIUR3_16644-P1|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1958041_1	448385.sce6526	3.032e-209	674.0	COG4886@1|root,COG4886@2|Bacteria,1P5D8@1224|Proteobacteria,433SH@68525|delta/epsilon subdivisions,2WXRP@28221|Deltaproteobacteria,2Z2SK@29|Myxococcales	28221|Deltaproteobacteria	S	DUF3160	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160
SHD3_k127_19687_5	1157708.KB907454_gene3008	1.428e-10	74.0	28WH1@1|root,2ZIH5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_19687_1	1499967.BAYZ01000159_gene506	2.655e-51	188.0	28JE3@1|root,2Z98B@2|Bacteria,2NQ8M@2323|unclassified Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SHD3_k127_19687_3	357808.RoseRS_1536	1.275e-20	102.0	COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia	32061|Chloroflexia	D	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SHD3_k127_19687_0	1192034.CAP_4354	2.316e-139	472.0	COG0402@1|root,COG4733@1|root,COG4935@1|root,COG0402@2|Bacteria,COG4733@2|Bacteria,COG4935@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2Z3N3@29|Myxococcales	28221|Deltaproteobacteria	DOZ	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_2,DUF4215
SHD3_k127_1972866_4	880072.Desac_1106	2.622e-23	102.0	2E32K@1|root,32Y2U@2|Bacteria,1NJTE@1224|Proteobacteria,42WY3@68525|delta/epsilon subdivisions,2WSR9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1972866_2	314278.NB231_06750	1.233e-89	305.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,1S0QR@1236|Gammaproteobacteria,1X00D@135613|Chromatiales	135613|Chromatiales	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SHD3_k127_1972866_5	1192034.CAP_4311	2.244e-21	103.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
SHD3_k127_1972866_7	644968.DFW101_0787	2.009e-13	77.0	2FD7F@1|root,3459F@2|Bacteria,1NZVP@1224|Proteobacteria,4363D@68525|delta/epsilon subdivisions,2X0MA@28221|Deltaproteobacteria,2MCTI@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1972866_6	1192034.CAP_1849	1.775e-18	92.0	COG0695@1|root,COG0695@2|Bacteria,1PPNM@1224|Proteobacteria,437CJ@68525|delta/epsilon subdivisions,2X2I6@28221|Deltaproteobacteria,2Z2DY@29|Myxococcales	28221|Deltaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SHD3_k127_1972866_3	1254432.SCE1572_40970	2.046e-23	115.0	2F8GF@1|root,340V9@2|Bacteria,1NXZ0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1972866_0	1123487.KB892834_gene2735	1.448e-186	590.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,2VP45@28216|Betaproteobacteria,2KY6W@206389|Rhodocyclales	206389|Rhodocyclales	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1972866_1	903818.KI912269_gene533	2.808e-146	471.0	COG1492@1|root,COG1492@2|Bacteria,3Y64K@57723|Acidobacteria	57723|Acidobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,CbiA,GATase_3
SHD3_k127_1979573_0	357808.RoseRS_0421	3.037e-123	429.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_1983399_2	63737.Npun_F0728	4.116e-73	256.0	COG4360@1|root,COG4360@2|Bacteria,1G2S9@1117|Cyanobacteria,1HIMD@1161|Nostocales	1117|Cyanobacteria	F	PFAM ATP adenylyltransferase	apa2	-	2.7.7.53	ko:K00988	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	ATP_transf
SHD3_k127_1983399_1	1267005.KB911258_gene458	2.881e-129	443.0	COG0791@1|root,COG0791@2|Bacteria,1MU8A@1224|Proteobacteria,2U1XU@28211|Alphaproteobacteria,3N8B1@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1983399_4	398512.JQKC01000006_gene743	1.863e-62	229.0	COG2006@1|root,COG2133@1|root,COG2006@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1983399_3	96561.Dole_2679	2.722e-63	233.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42T4H@68525|delta/epsilon subdivisions,2X5J5@28221|Deltaproteobacteria,2MPF5@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	6.3.2.10	ko:K01929,ko:K07282	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	PGA_cap
SHD3_k127_1983399_5	344747.PM8797T_30731	6.548e-54	203.0	COG1105@1|root,COG1105@2|Bacteria,2J14C@203682|Planctomycetes	203682|Planctomycetes	H	COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)	-	-	2.7.1.144	ko:K00917	ko00052,ko01100,map00052,map01100	-	R03236	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SHD3_k127_1983399_0	1254432.SCE1572_42365	3.071e-174	577.0	COG1193@1|root,COG1193@2|Bacteria,1QUJI@1224|Proteobacteria,42P7P@68525|delta/epsilon subdivisions,2WK5H@28221|Deltaproteobacteria,2YTYQ@29|Myxococcales	28221|Deltaproteobacteria	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SHD3_k127_1983399_6	1192034.CAP_6891	3.568e-13	70.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SHD3_k127_1996071_4	1242864.D187_006153	9.622e-24	117.0	29WSY@1|root,30IEA@2|Bacteria,1PV9U@1224|Proteobacteria,438BH@68525|delta/epsilon subdivisions,2X3KW@28221|Deltaproteobacteria,2YWGD@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_1996071_5	1123073.KB899241_gene2085	1.617e-17	96.0	COG0392@1|root,COG0392@2|Bacteria,1QCDR@1224|Proteobacteria,1T83P@1236|Gammaproteobacteria,1XBRH@135614|Xanthomonadales	135614|Xanthomonadales	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SHD3_k127_1996071_3	1192868.CAIU01000022_gene3197	4.368e-30	135.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,NodS
SHD3_k127_1996071_2	744872.Spica_1633	1.018e-32	147.0	COG1181@1|root,COG1181@2|Bacteria,2J5KK@203691|Spirochaetes	203691|Spirochaetes	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3,ATP-grasp_4
SHD3_k127_1996071_1	665571.STHERM_c17660	3.777e-60	228.0	COG0463@1|root,COG0463@2|Bacteria,2J7NM@203691|Spirochaetes	203691|Spirochaetes	M	glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721,ko:K20534	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SHD3_k127_1996071_0	1304872.JAGC01000003_gene3619	4.805e-105	356.0	COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,42MTX@68525|delta/epsilon subdivisions,2WITE@28221|Deltaproteobacteria,2M8SG@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the DegT DnrJ EryC1 family	arnB	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
SHD3_k127_2003567_0	502025.Hoch_4234	4.831e-189	615.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2YYYV@29|Myxococcales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SHD3_k127_2003567_2	357808.RoseRS_0552	4.892e-16	80.0	COG1918@1|root,COG1918@2|Bacteria,2G9XG@200795|Chloroflexi,377Q8@32061|Chloroflexia	32061|Chloroflexia	P	PFAM FeoA family protein	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SHD3_k127_2003567_3	519989.ECTPHS_11457	1.649e-07	64.0	COG2885@1|root,COG2885@2|Bacteria,1PGGZ@1224|Proteobacteria,1RNFU@1236|Gammaproteobacteria	1236|Gammaproteobacteria	N	COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins	motY	-	-	ko:K21218	ko02040,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SHD3_k127_2003567_4	1330700.JQNC01000003_gene918	2.067e-05	55.0	COG0745@1|root,COG0745@2|Bacteria,1WNER@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	KT	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SHD3_k127_2014240_4	383372.Rcas_0264	8.403e-40	151.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2014240_0	448385.sce0567	7.539e-212	683.0	COG3973@1|root,COG3973@2|Bacteria,1P638@1224|Proteobacteria,42MXR@68525|delta/epsilon subdivisions,2WK1Z@28221|Deltaproteobacteria,2Z32G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD_C_2
SHD3_k127_2014240_5	243090.RB12316	1.94e-38	154.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SHD3_k127_2014240_7	313606.M23134_03438	1.512e-12	79.0	COG0454@1|root,COG0456@2|Bacteria,4NN2Z@976|Bacteroidetes,47SNV@768503|Cytophagia	976|Bacteroidetes	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
SHD3_k127_2014240_6	1268239.PALB_16270	3.504e-20	101.0	2E74N@1|root,331P2@2|Bacteria,1RC0J@1224|Proteobacteria,1S2MI@1236|Gammaproteobacteria,2Q33T@267888|Pseudoalteromonadaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2014240_1	215803.DB30_6913	2.166e-137	492.0	COG0457@1|root,COG0457@2|Bacteria,1Q2SX@1224|Proteobacteria,438EQ@68525|delta/epsilon subdivisions,2X3PN@28221|Deltaproteobacteria,2YWSJ@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_7,TPR_8
SHD3_k127_2014240_3	1300345.LF41_948	2.21e-41	162.0	COG0084@1|root,COG0084@2|Bacteria,1MW5C@1224|Proteobacteria,1RP5T@1236|Gammaproteobacteria,1X402@135614|Xanthomonadales	135614|Xanthomonadales	L	Hydrolase, TatD family	yjjV	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
SHD3_k127_2014240_2	1192034.CAP_8441	8.019e-94	327.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
SHD3_k127_2017027_0	113395.AXAI01000012_gene7132	1.235e-137	449.0	COG0475@1|root,COG0475@2|Bacteria,1R7K4@1224|Proteobacteria,2U29N@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SHD3_k127_2017027_4	1353531.AZNX01000003_gene2998	1.204e-10	69.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,2U9AG@28211|Alphaproteobacteria,4BF17@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
SHD3_k127_2017027_1	521011.Mpal_2219	2.166e-85	304.0	COG2020@1|root,arCOG03580@2157|Archaea,2XWII@28890|Euryarchaeota,2NAK0@224756|Methanomicrobia	224756|Methanomicrobia	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SHD3_k127_2017027_2	436229.JOEH01000008_gene4097	3.337e-75	262.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,2NMCQ@228398|Streptacidiphilus	201174|Actinobacteria	G	Glycosyl hydrolase family 26	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SHD3_k127_2017027_3	436229.JOEH01000008_gene4097	1.697e-29	118.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,2NMCQ@228398|Streptacidiphilus	201174|Actinobacteria	G	Glycosyl hydrolase family 26	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SHD3_k127_2020667_1	378806.STAUR_7509	1.922e-120	406.0	2EGHW@1|root,33A9Z@2|Bacteria,1PM4Y@1224|Proteobacteria,43304@68525|delta/epsilon subdivisions,2WYJA@28221|Deltaproteobacteria,2Z1SV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2020667_2	269084.syc1605_c	1.389e-97	326.0	COG0722@1|root,COG0722@2|Bacteria,1G35W@1117|Cyanobacteria,1GYEV@1129|Synechococcus	1117|Cyanobacteria	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroG	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SHD3_k127_2020667_4	378806.STAUR_5810	2.144e-44	173.0	COG3148@1|root,COG3148@2|Bacteria,1QJQZ@1224|Proteobacteria,439DR@68525|delta/epsilon subdivisions,2X4NN@28221|Deltaproteobacteria,2YZB6@29|Myxococcales	28221|Deltaproteobacteria	S	DTW	-	-	-	-	-	-	-	-	-	-	-	-	DTW
SHD3_k127_2020667_7	5551.XP_003234541.1	8.105e-09	67.0	KOG1225@1|root,KOG1225@2759|Eukaryota	2759|Eukaryota	L	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	-	-	-	ko:K01691,ko:K13539	ko04310,map04310	-	-	-	ko00000,ko00001,ko01000,ko01002,ko03036	-	-	-	Peptidase_M8,WIF
SHD3_k127_2020667_3	575540.Isop_0364	3.132e-84	294.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,2J033@203682|Planctomycetes	203682|Planctomycetes	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Oxidored_q6
SHD3_k127_2020667_6	1123501.KB902310_gene51	2.799e-36	145.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2U9M1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
SHD3_k127_2020667_0	290397.Adeh_3659	3.595e-163	535.0	COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1QUBF@1224|Proteobacteria,42NJH@68525|delta/epsilon subdivisions,2WJ6J@28221|Deltaproteobacteria,2YZIA@29|Myxococcales	28221|Deltaproteobacteria	C	Respiratory-chain NADH dehydrogenase, 49 Kd subunit	ehrL	-	-	-	-	-	-	-	-	-	-	-	Complex1_30kDa,Complex1_49kDa
SHD3_k127_2020667_5	1120973.AQXL01000135_gene1425	3.066e-44	169.0	COG0651@1|root,COG0651@2|Bacteria,1TRAT@1239|Firmicutes,4HA10@91061|Bacilli	91061|Bacilli	CP	subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali	mrpD	GO:0003674,GO:0005215,GO:0005451,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0035725,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600	-	ko:K05568	-	-	-	-	ko00000,ko02000	2.A.63.1,2.A.63.2	-	iSB619.SA_RS04615	Proton_antipo_M
SHD3_k127_2027241_2	794903.OPIT5_09350	5.289e-35	146.0	COG2207@1|root,COG2207@2|Bacteria,46Y3Q@74201|Verrucomicrobia,3K8VU@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SHD3_k127_2027241_1	1121929.KB898663_gene1074	6.747e-50	202.0	COG3664@1|root,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,4HE9D@91061|Bacilli,471EQ@74385|Gracilibacillus	91061|Bacilli	G	Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
SHD3_k127_2027241_0	1254432.SCE1572_39610	1.319e-135	455.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,43836@68525|delta/epsilon subdivisions,2X3D4@28221|Deltaproteobacteria,2YVHE@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 30 family	srfJ	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C,RicinB_lectin_2
SHD3_k127_2035234_15	1002804.HBZC1_09700	1.363e-16	93.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42M5H@68525|delta/epsilon subdivisions,2YTME@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
SHD3_k127_2035234_9	1123508.JH636445_gene6724	2.99e-61	226.0	COG0524@1|root,COG0524@2|Bacteria,2IZDG@203682|Planctomycetes	203682|Planctomycetes	G	COG0524 Sugar kinases, ribokinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SHD3_k127_2035234_4	1254432.SCE1572_42390	4.086e-129	426.0	COG0681@1|root,COG0711@1|root,COG0681@2|Bacteria,COG0711@2|Bacteria,1MXUF@1224|Proteobacteria,42NJE@68525|delta/epsilon subdivisions,2WKMA@28221|Deltaproteobacteria,2YV8J@29|Myxococcales	28221|Deltaproteobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
SHD3_k127_2035234_0	378806.STAUR_4485	1.295e-200	643.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43C02@68525|delta/epsilon subdivisions,2X7AU@28221|Deltaproteobacteria,2YU9K@29|Myxococcales	28221|Deltaproteobacteria	KT	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_2035234_1	1254432.SCE1572_44120	3.281e-159	518.0	COG3266@1|root,COG3266@2|Bacteria,1PBVF@1224|Proteobacteria,4384T@68525|delta/epsilon subdivisions,2X3EV@28221|Deltaproteobacteria,2YVRI@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	dCache_3
SHD3_k127_2035234_3	1254432.SCE1572_44130	4.724e-145	465.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2YUI6@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
SHD3_k127_2035234_7	448385.sce7637	8.98e-75	266.0	COG1573@1|root,COG1573@2|Bacteria,1MWX1@1224|Proteobacteria,42QXV@68525|delta/epsilon subdivisions,2WS71@28221|Deltaproteobacteria,2Z31Q@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SHD3_k127_2035234_14	1192034.CAP_7416	2.832e-19	94.0	COG3815@1|root,COG3815@2|Bacteria	2|Bacteria	S	Predicted membrane protein (DUF2085)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2085
SHD3_k127_2035234_11	448385.sce4472	2.233e-45	184.0	2AH4I@1|root,317E5@2|Bacteria,1PYQB@1224|Proteobacteria,435HF@68525|delta/epsilon subdivisions,2X99V@28221|Deltaproteobacteria,2Z2T7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2035234_2	448385.sce4471	4.273e-145	468.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YZ61@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
SHD3_k127_2035234_12	1192034.CAP_0106	3.919e-44	161.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SHD3_k127_2043644_3	246197.MXAN_3600	5.283e-15	81.0	COG5659@1|root,COG5659@2|Bacteria,1MXSV@1224|Proteobacteria,42UR2@68525|delta/epsilon subdivisions,2WQER@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_5
SHD3_k127_2043644_2	1192034.CAP_2127	5.62e-43	171.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_2043644_0	1192034.CAP_5604	2.052e-106	363.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
SHD3_k127_2043644_1	502025.Hoch_0884	1.103e-44	181.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,PEGA,Pkinase,TPR_12
SHD3_k127_2043644_4	1254432.SCE1572_33125	0.000958	45.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_33125|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2051111_0	378806.STAUR_1706	2.536e-139	458.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YZTT@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	frgC	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_2051111_1	448385.sce6675	1.863e-73	259.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce6675|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2051111_2	10228.TriadP31757	1.98e-68	254.0	COG1960@1|root,KOG0137@2759|Eukaryota,38EKS@33154|Opisthokonta,3B9YX@33208|Metazoa	33208|Metazoa	I	long-chain-acyl-CoA dehydrogenase activity	ACADVL	GO:0000038,GO:0000062,GO:0000166,GO:0001659,GO:0003674,GO:0003824,GO:0003995,GO:0004466,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005829,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0006986,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010565,GO:0015980,GO:0016020,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0017099,GO:0019216,GO:0019217,GO:0019218,GO:0019222,GO:0019395,GO:0019752,GO:0019866,GO:0023052,GO:0030154,GO:0030258,GO:0030554,GO:0030855,GO:0030968,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033554,GO:0034440,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0036094,GO:0036498,GO:0042221,GO:0042304,GO:0042592,GO:0042645,GO:0042760,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0046395,GO:0046890,GO:0048037,GO:0048519,GO:0048523,GO:0048856,GO:0048869,GO:0048871,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051055,GO:0051716,GO:0055114,GO:0060429,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0070013,GO:0070887,GO:0071310,GO:0071704,GO:0072329,GO:0080090,GO:0090181,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.9	ko:K09479	ko00071,ko01100,ko01212,map00071,map01100,map01212	M00087	R01279	RC00052	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
SHD3_k127_2051111_3	891968.Anamo_1626	4.426e-50	197.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SHD3_k127_2051111_4	537972.ABQU01000040_gene1726	1.973e-06	53.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2YPX3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SHD3_k127_2075025_4	448385.sce5508	2.116e-64	227.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_2075025_1	448385.sce5506	3.578e-137	450.0	COG3405@1|root,COG3405@2|Bacteria,1R633@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolases family 8	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM_2,Glyco_hydro_8
SHD3_k127_2075025_3	632292.Calhy_0729	1.626e-67	248.0	COG1533@1|root,COG1533@2|Bacteria,1V24S@1239|Firmicutes,24BVY@186801|Clostridia	186801|Clostridia	L	PFAM Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SHD3_k127_2075025_6	909663.KI867150_gene795	2.296e-56	221.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42QFH@68525|delta/epsilon subdivisions,2WKWR@28221|Deltaproteobacteria,2MREA@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_2075025_8	215803.DB30_5413	9.405e-24	108.0	COG0586@1|root,COG0586@2|Bacteria,1R6V4@1224|Proteobacteria,42XP4@68525|delta/epsilon subdivisions,2WT5P@28221|Deltaproteobacteria,2YW30@29|Myxococcales	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SHD3_k127_2075025_0	398767.Glov_2185	1.319e-149	489.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42MVS@68525|delta/epsilon subdivisions,2WJKA@28221|Deltaproteobacteria,43TEP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_2075025_5	756272.Plabr_4506	4.319e-64	228.0	COG0652@1|root,COG0652@2|Bacteria,2IZWK@203682|Planctomycetes	203682|Planctomycetes	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SHD3_k127_2075025_2	555079.Toce_1741	5.198e-105	346.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,42HNP@68295|Thermoanaerobacterales	186801|Clostridia	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
SHD3_k127_2083278_4	1123054.KB907708_gene2013	8.012e-06	50.0	COG1012@1|root,COG1012@2|Bacteria,1MV2I@1224|Proteobacteria,1RPQW@1236|Gammaproteobacteria,1X0BM@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SHD3_k127_2083278_1	1073999.BN137_3319	4.368e-75	265.0	COG3138@1|root,COG3138@2|Bacteria,1MWHC@1224|Proteobacteria,1RMXG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	arginine N-succinyltransferase	astA	-	2.3.1.109	ko:K00673	ko00330,ko01100,map00330,map01100	-	R00832	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	iE2348C_1286.E2348C_1875	AstA
SHD3_k127_2083278_0	452637.Oter_1688	5.022e-121	401.0	COG0624@1|root,COG0624@2|Bacteria	2|Bacteria	E	succinyl-diaminopimelate desuccinylase activity	cpg2	-	3.4.17.11	ko:K01295	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SHD3_k127_2083278_2	1254432.SCE1572_02325	1.202e-13	81.0	2DK48@1|root,308EE@2|Bacteria,1QSG3@1224|Proteobacteria,4357G@68525|delta/epsilon subdivisions,2WZIH@28221|Deltaproteobacteria,2Z27V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2084541_0	1254432.SCE1572_21755	6.537e-273	869.0	COG1413@1|root,COG3119@1|root,COG1413@2|Bacteria,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,42V1G@68525|delta/epsilon subdivisions,2WRCZ@28221|Deltaproteobacteria,2YWCA@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SHD3_k127_2084541_3	448385.sce3593	3.622e-35	151.0	COG0457@1|root,COG0457@2|Bacteria,1N8F7@1224|Proteobacteria,42VYY@68525|delta/epsilon subdivisions,2WSH2@28221|Deltaproteobacteria,2YW0E@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_21,TPR_6,TPR_8
SHD3_k127_2084541_1	448385.sce3592	2.748e-159	512.0	COG1520@1|root,COG1520@2|Bacteria,1MXIJ@1224|Proteobacteria,42V3F@68525|delta/epsilon subdivisions,2WR8K@28221|Deltaproteobacteria,2YVGH@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ enzyme repeat	yfgL	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
SHD3_k127_2084541_2	1254432.SCE1572_17115	1.66e-109	359.0	COG1234@1|root,COG1234@2|Bacteria,1QU4B@1224|Proteobacteria,42SHU@68525|delta/epsilon subdivisions,2WPGG@28221|Deltaproteobacteria,2YWV3@29|Myxococcales	28221|Deltaproteobacteria	S	cAMP phosphodiesterases class-II	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2,PDEase_II
SHD3_k127_2085621_3	448385.sce8025	2.875e-09	59.0	COG0839@1|root,COG0839@2|Bacteria,1PJW9@1224|Proteobacteria,42V0F@68525|delta/epsilon subdivisions,2WS8G@28221|Deltaproteobacteria,2Z1CQ@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the complex I subunit 6 family	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SHD3_k127_2085621_2	404589.Anae109_1284	1.147e-41	161.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42SZV@68525|delta/epsilon subdivisions,2WP8T@28221|Deltaproteobacteria,2Z0UI@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338,ko:K05580	ko00190,ko01100,map00190,map01100	M00144,M00145	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_4,Fer4_7
SHD3_k127_2085621_1	1254432.SCE1572_43755	3.438e-127	423.0	COG0265@1|root,COG1005@1|root,COG0265@2|Bacteria,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YYND@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh,PDZ_2
SHD3_k127_2085621_0	404589.Anae109_1286	4.084e-144	474.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YWJS@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
SHD3_k127_2093116_4	448385.sce0831	1.566e-44	178.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_2093116_9	1312954.KI914856_gene1167	8.461e-16	85.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_2093116_11	391625.PPSIR1_00085	1.409e-12	81.0	COG3712@1|root,COG3712@2|Bacteria,1PBZ9@1224|Proteobacteria,433U5@68525|delta/epsilon subdivisions,2X3GP@28221|Deltaproteobacteria,2YW0J@29|Myxococcales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,zf-HC2
SHD3_k127_2093116_7	404589.Anae109_2744	1.084e-37	157.0	2AJ10@1|root,319J4@2|Bacteria,1Q2X4@1224|Proteobacteria,438K5@68525|delta/epsilon subdivisions,2X3UQ@28221|Deltaproteobacteria,2YX5Z@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2093116_2	1254432.SCE1572_11370	4.58e-47	180.0	COG2885@1|root,COG2885@2|Bacteria,1MZKA@1224|Proteobacteria,42U2D@68525|delta/epsilon subdivisions,2X3AZ@28221|Deltaproteobacteria,2YV6S@29|Myxococcales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SHD3_k127_2093116_6	857087.Metme_3737	2.925e-43	171.0	COG5621@1|root,COG5621@2|Bacteria,1MUVF@1224|Proteobacteria,1RZ65@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	secreted hydrolase	attH	-	-	-	-	-	-	-	-	-	-	-	CrtC,Lipocalin_9
SHD3_k127_2093116_0	204669.Acid345_3014	4.881e-85	305.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_2093116_1	1254432.SCE1572_11160	1.572e-76	280.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,433ZY@68525|delta/epsilon subdivisions,2X4BJ@28221|Deltaproteobacteria,2Z0YV@29|Myxococcales	28221|Deltaproteobacteria	M	Spore coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
SHD3_k127_2093116_8	316274.Haur_2512	1.768e-20	93.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16,HemolysinCabind
SHD3_k127_209341_4	502025.Hoch_2910	1.711e-18	85.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2YV8H@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SHD3_k127_209341_0	368407.Memar_2263	1.205e-35	142.0	arCOG09456@1|root,arCOG09456@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_209341_3	266762.HQ36_01780	1.799e-24	108.0	2F643@1|root,33YND@2|Bacteria,4P41A@976|Bacteroidetes,2FSU4@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_209341_2	391625.PPSIR1_12233	6.886e-27	123.0	COG0768@1|root,COG0768@2|Bacteria	2|Bacteria	M	penicillin binding	pbp2B	-	3.4.16.4	ko:K01286	-	-	-	-	ko00000,ko01000	-	-	-	MecA_N,PBP_dimer,Peptidase_C39_2,Peptidase_C70,Transpeptidase
SHD3_k127_209341_1	314271.RB2654_11303	5.54e-35	137.0	COG0346@1|root,COG0346@2|Bacteria,1N0CH@1224|Proteobacteria,2UDI5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SHD3_k127_209341_5	1279017.AQYJ01000023_gene3301	1.033e-12	71.0	2DU0N@1|root,33NF9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_209341_6	324925.Ppha_1724	0.0002964	44.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
SHD3_k127_2105751_8	448385.sce2996	3.357e-31	123.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,2YW1G@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
SHD3_k127_2105751_0	290398.Csal_2440	1.055e-265	839.0	COG0542@1|root,COG0542@2|Bacteria,1MV8B@1224|Proteobacteria,1RMH3@1236|Gammaproteobacteria,1XHDW@135619|Oceanospirillales	135619|Oceanospirillales	O	Belongs to the ClpA ClpB family	clpA	-	-	ko:K03694	-	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SHD3_k127_2105751_7	448385.sce4389	5.314e-36	139.0	COG2127@1|root,COG2127@2|Bacteria,1MZU8@1224|Proteobacteria,42TN3@68525|delta/epsilon subdivisions,2WQ23@28221|Deltaproteobacteria,2YVP9@29|Myxococcales	28221|Deltaproteobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
SHD3_k127_2105751_5	1254432.SCE1572_37285	2.922e-44	181.0	COG1388@1|root,COG3108@1|root,COG1388@2|Bacteria,COG3108@2|Bacteria,1QABK@1224|Proteobacteria,434YH@68525|delta/epsilon subdivisions,2WZ9D@28221|Deltaproteobacteria,2Z1MT@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_2
SHD3_k127_2105751_6	1192034.CAP_5004	2.023e-36	145.0	2E4IQ@1|root,32ZDS@2|Bacteria,1NBEP@1224|Proteobacteria,431T4@68525|delta/epsilon subdivisions,2WW82@28221|Deltaproteobacteria,2YVWC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2105751_2	448385.sce3766	1.266e-74	271.0	COG0515@1|root,COG0515@2|Bacteria,1PFJ6@1224|Proteobacteria,4340Z@68525|delta/epsilon subdivisions,2X4J2@28221|Deltaproteobacteria,2YZ45@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_2105751_1	448385.sce1649	5.801e-214	674.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YX5F@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	nla19	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_2105751_3	1192034.CAP_7169	2.657e-71	248.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria,2YUD8@29|Myxococcales	28221|Deltaproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SHD3_k127_2111918_6	3988.XP_002537145.1	6.303e-19	89.0	COG0693@1|root,KOG2764@2759|Eukaryota	2759|Eukaryota	J	guanine deglycation, methylglyoxal removal	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SHD3_k127_2111918_3	391625.PPSIR1_27218	1.348e-57	220.0	COG2939@1|root,COG2939@2|Bacteria,1Q4XB@1224|Proteobacteria,4302Y@68525|delta/epsilon subdivisions,2WV8P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SHD3_k127_2111918_2	1254432.SCE1572_07050	1.847e-75	276.0	COG3119@1|root,COG3119@2|Bacteria,1QZST@1224|Proteobacteria,43CMS@68525|delta/epsilon subdivisions,2X7UX@28221|Deltaproteobacteria,2Z29A@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SHD3_k127_2111918_5	216596.RL2179	1.975e-32	136.0	COG1409@1|root,COG1409@2|Bacteria,1R4AZ@1224|Proteobacteria,2U884@28211|Alphaproteobacteria,4BB97@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
SHD3_k127_2111918_4	1254432.SCE1572_01640	1.448e-45	175.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K02624,ko:K13641	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
SHD3_k127_2111918_1	1254432.SCE1572_01645	2.418e-100	339.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SHD3_k127_2111918_0	96561.Dole_0365	4.312e-108	357.0	COG1032@1|root,COG1032@2|Bacteria,1P9J0@1224|Proteobacteria,42MWG@68525|delta/epsilon subdivisions,2WIV5@28221|Deltaproteobacteria,2MI1A@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SHD3_k127_2112543_3	448385.sce3103	1.276e-21	97.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42XMH@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF1566,EF-hand_5
SHD3_k127_2112543_1	383372.Rcas_3687	7.551e-32	128.0	COG3744@1|root,COG3744@2|Bacteria,2G9CV@200795|Chloroflexi,377FA@32061|Chloroflexia	32061|Chloroflexia	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_2112543_2	215803.DB30_0231	3.033e-22	100.0	COG2337@1|root,COG2337@2|Bacteria,1N1DE@1224|Proteobacteria,42WAI@68525|delta/epsilon subdivisions,2WRAJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SHD3_k127_2112543_4	983917.RGE_18140	1.831e-06	56.0	COG0210@1|root,COG0210@2|Bacteria,1P8RH@1224|Proteobacteria,2VIW9@28216|Betaproteobacteria	28216|Betaproteobacteria	L	Uvrd rep helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C,UvrD_C_2
SHD3_k127_2112543_0	448385.sce8989	1.002e-249	822.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_215248_3	326427.Cagg_3669	4.734e-41	167.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G6F0@200795|Chloroflexi,377HR@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
SHD3_k127_215248_0	448385.sce8175	5.218e-204	674.0	COG4932@1|root,COG4932@2|Bacteria,1PF83@1224|Proteobacteria,430QE@68525|delta/epsilon subdivisions,2WVYF@28221|Deltaproteobacteria,2Z1TZ@29|Myxococcales	28221|Deltaproteobacteria	M	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SHD3_k127_215248_1	1254432.SCE1572_07800	1.011e-88	317.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_215248_5	497321.C664_04042	2.228e-07	64.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,2VPB3@28216|Betaproteobacteria,2KVVY@206389|Rhodocyclales	206389|Rhodocyclales	S	COG0457 FOG TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_4,TPR_8
SHD3_k127_215248_2	383372.Rcas_0517	3.165e-54	217.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria	2|Bacteria	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,Spermine_synt_N,Spermine_synth
SHD3_k127_2157111_9	1068980.ARVW01000001_gene3010	1.03e-08	60.0	2DSMY@1|root,33GQS@2|Bacteria,2GVW6@201174|Actinobacteria,4E7K8@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
SHD3_k127_2157111_4	1242864.D187_007537	2.789e-123	407.0	COG1482@1|root,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,42QR1@68525|delta/epsilon subdivisions,2WU24@28221|Deltaproteobacteria,2YUXK@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphomannose isomerase type I	-	-	5.3.1.8,5.4.2.8	ko:K01809,ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818,R01819	RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
SHD3_k127_2157111_3	448385.sce5900	5.039e-126	420.0	COG3572@1|root,COG3572@2|Bacteria,1MU47@1224|Proteobacteria,42QDI@68525|delta/epsilon subdivisions,2WJMG@28221|Deltaproteobacteria,2YWDT@29|Myxococcales	28221|Deltaproteobacteria	H	glutamate--cysteine ligase	gshA	-	6.3.2.2	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00894,R10993	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	GCS2
SHD3_k127_2157111_7	1254432.SCE1572_35170	4.913e-49	186.0	COG2040@1|root,COG2040@2|Bacteria	2|Bacteria	E	homocysteine	-	-	2.1.1.10	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	-	R00650	RC00003,RC00035	ko00000,ko00001,ko01000	-	-	-	S-methyl_trans
SHD3_k127_2157111_6	448385.sce1711	1.126e-67	236.0	COG1403@1|root,COG1403@2|Bacteria,1MWEQ@1224|Proteobacteria,437B2@68525|delta/epsilon subdivisions,2X2FR@28221|Deltaproteobacteria,2Z0QW@29|Myxococcales	28221|Deltaproteobacteria	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
SHD3_k127_2157111_0	1254432.SCE1572_35175	0.0	1115.0	COG2304@1|root,COG2304@2|Bacteria,1N4IM@1224|Proteobacteria,437ZC@68525|delta/epsilon subdivisions,2WZWU@28221|Deltaproteobacteria,2YUXT@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA
SHD3_k127_2157111_8	1192034.CAP_0064	2.934e-10	70.0	COG2304@1|root,COG2304@2|Bacteria,1N4IM@1224|Proteobacteria,437ZC@68525|delta/epsilon subdivisions,2WZWU@28221|Deltaproteobacteria,2YUXT@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like,VWA
SHD3_k127_2157111_1	1192034.CAP_0063	1.878e-231	734.0	COG2304@1|root,COG2304@2|Bacteria,1PYZT@1224|Proteobacteria,435MP@68525|delta/epsilon subdivisions,2XA2Q@28221|Deltaproteobacteria,2YYF8@29|Myxococcales	28221|Deltaproteobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SHD3_k127_2157111_2	1192034.CAP_0062	1.497e-142	458.0	COG1721@1|root,COG1721@2|Bacteria,1NEAC@1224|Proteobacteria,43B78@68525|delta/epsilon subdivisions,2X6KP@28221|Deltaproteobacteria,2YWA8@29|Myxococcales	28221|Deltaproteobacteria	S	Von Willebrand factor type A	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SHD3_k127_2157111_5	448385.sce5905	4.405e-119	387.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YYCD@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SHD3_k127_2170421_6	429009.Adeg_0820	2.089e-11	68.0	COG2253@1|root,COG2253@2|Bacteria,1UKDE@1239|Firmicutes,25FUI@186801|Clostridia,42IRB@68295|Thermoanaerobacterales	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SHD3_k127_2170421_4	1283300.ATXB01000001_gene300	9.19e-15	79.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria,1SBYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_2170421_3	96561.Dole_0571	1.263e-17	91.0	COG1011@1|root,COG1011@2|Bacteria,1Q69Y@1224|Proteobacteria,437ES@68525|delta/epsilon subdivisions,2XA2M@28221|Deltaproteobacteria,2MP7F@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Hydrolase	-	-	3.1.3.10	ko:K20866	ko00010,ko01120,map00010,map01120	-	R00947	RC00078	ko00000,ko00001,ko01000	-	-	-	-
SHD3_k127_2170421_0	448385.sce2957	5.411e-87	320.0	COG1413@1|root,COG3266@1|root,COG1413@2|Bacteria,COG3266@2|Bacteria,1QX4H@1224|Proteobacteria,42Z02@68525|delta/epsilon subdivisions,2WUJ9@28221|Deltaproteobacteria,2YVP1@29|Myxococcales	28221|Deltaproteobacteria	C	Type II secretion system (T2SS), protein E, N-terminal domain	frgA	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,T2SSE_N
SHD3_k127_2170421_1	215803.DB30_7594	1.894e-64	233.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SHD3_k127_2170421_5	1306990.BARG01000024_gene2498	1.78e-11	77.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_2178112_5	1192034.CAP_0380	1.623e-65	226.0	COG2131@1|root,COG2131@2|Bacteria,1RD1P@1224|Proteobacteria,42RHI@68525|delta/epsilon subdivisions,2WNGV@28221|Deltaproteobacteria,2YV1R@29|Myxococcales	28221|Deltaproteobacteria	F	deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
SHD3_k127_2178112_2	1254432.SCE1572_51235	4.803e-143	471.0	COG0151@1|root,COG0151@2|Bacteria,1MUAH@1224|Proteobacteria,42MCI@68525|delta/epsilon subdivisions,2WJ7H@28221|Deltaproteobacteria,2YU6X@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the GARS family	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC,GARS_A,GARS_C,GARS_N
SHD3_k127_2178112_0	448385.sce4397	4.226e-154	495.0	COG1932@1|root,COG1932@2|Bacteria,1MUB5@1224|Proteobacteria,42MEN@68525|delta/epsilon subdivisions,2WIYF@28221|Deltaproteobacteria,2YUH6@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
SHD3_k127_2178112_1	1125863.JAFN01000001_gene1833	1.103e-152	498.0	COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,42M1C@68525|delta/epsilon subdivisions,2WIZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
SHD3_k127_2178112_10	1192034.CAP_0383	1.212e-26	120.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SHD3_k127_2178112_6	448385.sce9011	3.236e-62	230.0	COG1716@1|root,COG1716@2|Bacteria,1PFN8@1224|Proteobacteria,435DQ@68525|delta/epsilon subdivisions,2WZR8@28221|Deltaproteobacteria,2Z2JZ@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SHD3_k127_2178112_9	227086.JGI_V11_91426	4.876e-34	145.0	KOG3987@1|root,KOG3987@2759|Eukaryota	2759|Eukaryota	S	DREV methyltransferase	METTL9	-	-	ko:K18328	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DREV
SHD3_k127_2178112_4	1254432.SCE1572_29440	1.744e-90	302.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,42PC4@68525|delta/epsilon subdivisions,2WMG6@28221|Deltaproteobacteria,2YXXU@29|Myxococcales	28221|Deltaproteobacteria	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
SHD3_k127_2178112_3	448385.sce4295	2.581e-96	326.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP,CarboxypepD_reg,HemolysinCabind
SHD3_k127_2178685_1	880073.Calab_2930	3.503e-164	527.0	COG1830@1|root,COG1830@2|Bacteria,2NPYP@2323|unclassified Bacteria	2|Bacteria	G	DeoC/LacD family aldolase	fbaB	GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	iETEC_1333.ETEC_2236,iSBO_1134.SBO_0918,iUMNK88_1353.UMNK88_2640	DeoC
SHD3_k127_2178685_6	1123368.AUIS01000019_gene1198	1.507e-38	147.0	COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1SAUS@1236|Gammaproteobacteria,2ND7I@225057|Acidithiobacillales	225057|Acidithiobacillales	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
SHD3_k127_2178685_7	1123392.AQWL01000003_gene136	8.258e-35	139.0	COG2151@1|root,COG2151@2|Bacteria,1MZ9Y@1224|Proteobacteria,2VPN0@28216|Betaproteobacteria,1KTFF@119069|Hydrogenophilales	119069|Hydrogenophilales	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
SHD3_k127_2178685_5	296591.Bpro_4273	9.908e-40	152.0	COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,2VQ3A@28216|Betaproteobacteria,4ADT9@80864|Comamonadaceae	28216|Betaproteobacteria	C	TIGRFAM SUF system FeS assembly protein, NifU family	-	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
SHD3_k127_2178685_2	502025.Hoch_3281	7.754e-157	509.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	sufS	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
SHD3_k127_2178685_4	502025.Hoch_3282	3.878e-79	282.0	COG0719@1|root,COG0719@2|Bacteria,1MVK0@1224|Proteobacteria,42QXC@68525|delta/epsilon subdivisions,2WN3M@28221|Deltaproteobacteria,2Z0A5@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly protein SufD	sufD	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
SHD3_k127_2178685_3	1297742.A176_03526	2.037e-101	342.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,42PD0@68525|delta/epsilon subdivisions,2WJV3@28221|Deltaproteobacteria,2YWBY@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly ATPase SufC	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
SHD3_k127_2178685_0	502025.Hoch_3284	1.18e-232	727.0	COG0719@1|root,COG0719@2|Bacteria,1MVKY@1224|Proteobacteria,42NJ3@68525|delta/epsilon subdivisions,2WM3R@28221|Deltaproteobacteria,2YX6W@29|Myxococcales	28221|Deltaproteobacteria	O	FeS assembly protein SufB	sufB	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
SHD3_k127_2178685_8	105559.Nwat_0643	4.725e-29	126.0	COG1959@1|root,COG1959@2|Bacteria,1N0E2@1224|Proteobacteria,1S915@1236|Gammaproteobacteria,1X1A7@135613|Chromatiales	135613|Chromatiales	K	transcriptional regulator, Rrf2 family	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SHD3_k127_2178685_9	290397.Adeh_3956	6.179e-26	119.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2181008_3	1394178.AWOO02000007_gene3068	3.664e-22	100.0	COG1028@1|root,COG1028@2|Bacteria,2GIYQ@201174|Actinobacteria,4EP4I@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_2181008_1	1192034.CAP_2197	5.449e-28	130.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SHD3_k127_2181008_2	235909.GK1090	5.406e-24	108.0	COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,4HHE6@91061|Bacilli,1WGE1@129337|Geobacillus	91061|Bacilli	S	Domain in cystathionine beta-synthase and other proteins.	ylbB	-	-	-	-	-	-	-	-	-	-	-	CBS
SHD3_k127_2181597_11	1192034.CAP_1682	7.32e-34	138.0	2ARJ8@1|root,31GVS@2|Bacteria,1Q9YM@1224|Proteobacteria,434PT@68525|delta/epsilon subdivisions,2WZ11@28221|Deltaproteobacteria,2Z138@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2181597_8	448385.sce7269	2.811e-55	198.0	COG0781@1|root,COG0781@2|Bacteria,1N94P@1224|Proteobacteria,42SEA@68525|delta/epsilon subdivisions,2WQP9@28221|Deltaproteobacteria,2YVKR@29|Myxococcales	28221|Deltaproteobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
SHD3_k127_2181597_9	448385.sce8126	1.239e-48	184.0	2BPA6@1|root,32I21@2|Bacteria,1Q1NP@1224|Proteobacteria,437D0@68525|delta/epsilon subdivisions,2X2J2@28221|Deltaproteobacteria,2YVZ4@29|Myxococcales	28221|Deltaproteobacteria	S	Cytosol aminopeptidase family, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M17_N
SHD3_k127_2181597_5	448385.sce8296	9.208e-91	307.0	COG0003@1|root,COG0003@2|Bacteria,1NA7C@1224|Proteobacteria,42V2J@68525|delta/epsilon subdivisions,2WS25@28221|Deltaproteobacteria,2YUZS@29|Myxococcales	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SHD3_k127_2181597_4	448385.sce8018	1.663e-91	321.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce8018|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2181597_7	1254432.SCE1572_45705	4.792e-70	254.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,SapC
SHD3_k127_2181597_10	1157943.KB892706_gene4160	2.231e-47	179.0	COG2114@1|root,COG2114@2|Bacteria,2IE0W@201174|Actinobacteria,236AM@1762|Mycobacteriaceae	201174|Actinobacteria	T	Adenylate guanylate cyclase	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_cyc,YHS
SHD3_k127_2181597_15	1217720.ALOX01000004_gene4169	1.325e-06	59.0	COG1357@1|root,COG1357@2|Bacteria,1MZMI@1224|Proteobacteria,2UBB1@28211|Alphaproteobacteria,2JSRH@204441|Rhodospirillales	204441|Rhodospirillales	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SHD3_k127_2181597_13	1254432.SCE1572_52010	4.445e-19	98.0	COG3031@1|root,COG3031@2|Bacteria,1NB50@1224|Proteobacteria,42WPG@68525|delta/epsilon subdivisions,2WREX@28221|Deltaproteobacteria,2YVJ9@29|Myxococcales	28221|Deltaproteobacteria	U	General secretion pathway protein C	gspC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
SHD3_k127_2181597_6	448385.sce8018	8.45e-79	278.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce8018|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2181597_0	933262.AXAM01000004_gene2415	5.418e-281	892.0	COG0204@1|root,COG0318@1|root,COG0204@2|Bacteria,COG0318@2|Bacteria,1MWDY@1224|Proteobacteria,43BJD@68525|delta/epsilon subdivisions,2WIZT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	phospholipid glycerol acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,Acyltransferase,MFS_1,PP-binding
SHD3_k127_2181597_1	1254432.SCE1572_48485	2.274e-167	540.0	COG1032@1|root,COG1032@2|Bacteria,1MU15@1224|Proteobacteria,42N12@68525|delta/epsilon subdivisions,2WK0X@28221|Deltaproteobacteria,2YUG3@29|Myxococcales	28221|Deltaproteobacteria	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SHD3_k127_2181597_2	1192034.CAP_4560	2.945e-110	375.0	COG0863@1|root,COG0863@2|Bacteria,1NCJF@1224|Proteobacteria,42WGQ@68525|delta/epsilon subdivisions,2WS8Q@28221|Deltaproteobacteria,2YVW5@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SHD3_k127_2181597_16	1254432.SCE1572_28565	0.0001326	51.0	COG3793@1|root,COG3793@2|Bacteria	2|Bacteria	P	PFAM Mo-dependent nitrogenase	-	-	-	-	-	-	-	-	-	-	-	-	TerB
SHD3_k127_2181597_3	1254432.SCE1572_52595	1.797e-97	335.0	COG2843@1|root,COG2843@2|Bacteria,1P1MG@1224|Proteobacteria,42UTJ@68525|delta/epsilon subdivisions,2X5J6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SHD3_k127_2181597_12	244582.JQAK01000004_gene339	1.687e-20	94.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,2TVCY@28211|Alphaproteobacteria,47F9X@766|Rickettsiales	766|Rickettsiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SHD3_k127_2189955_1	1254432.SCE1572_48695	2.219e-155	512.0	COG1696@1|root,COG1696@2|Bacteria,1MUXN@1224|Proteobacteria,42MIR@68525|delta/epsilon subdivisions,2WMEK@28221|Deltaproteobacteria,2YU2I@29|Myxococcales	28221|Deltaproteobacteria	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
SHD3_k127_2189955_0	448385.sce5911	2.546e-279	866.0	COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,42M52@68525|delta/epsilon subdivisions,2WIRK@28221|Deltaproteobacteria,2YUQN@29|Myxococcales	28221|Deltaproteobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
SHD3_k127_2189955_2	448385.sce5910	4.935e-45	164.0	COG0234@1|root,COG0234@2|Bacteria,1MZ2X@1224|Proteobacteria,42U7E@68525|delta/epsilon subdivisions,2WPZP@28221|Deltaproteobacteria,2YVK0@29|Myxococcales	28221|Deltaproteobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
SHD3_k127_2189955_5	1121362.A605_00865	1.358e-06	56.0	2B4YQ@1|root,31XRP@2|Bacteria,2HZCJ@201174|Actinobacteria,22R7E@1653|Corynebacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3024)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3024
SHD3_k127_2195719_4	426117.M446_5027	1.265e-48	174.0	COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,2U5FW@28211|Alphaproteobacteria,1JUN8@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF1348)	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
SHD3_k127_2195719_2	338966.Ppro_1996	5.17e-69	245.0	COG0111@1|root,COG0111@2|Bacteria,1MW1U@1224|Proteobacteria,42Y5S@68525|delta/epsilon subdivisions,2WUB2@28221|Deltaproteobacteria,43TAN@69541|Desulfuromonadales	28221|Deltaproteobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh_C
SHD3_k127_2195719_0	2325.TKV_c02260	3.552e-130	434.0	COG0297@1|root,COG0297@2|Bacteria,1UHYC@1239|Firmicutes,24ANR@186801|Clostridia,42FD7@68295|Thermoanaerobacterales	186801|Clostridia	G	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_2195719_1	1499967.BAYZ01000068_gene1973	1.799e-102	355.0	COG0448@1|root,COG0448@2|Bacteria,2NPBS@2323|unclassified Bacteria	2|Bacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27,2.7.7.91	ko:K00975,ko:K20427	ko00500,ko00520,ko00525,ko01100,ko01110,ko01130,ko02026,map00500,map00520,map00525,map01100,map01110,map01130,map02026	M00565,M00814	R00948,R11237,R11246,R11402	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SHD3_k127_2195719_3	1068978.AMETH_3794	2.497e-64	229.0	2DSRU@1|root,33H7E@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_12
SHD3_k127_2195719_6	349102.Rsph17025_2699	2.184e-18	91.0	COG3237@1|root,COG3237@2|Bacteria,1N6X4@1224|Proteobacteria,2UF5Q@28211|Alphaproteobacteria,1FD26@1060|Rhodobacter	28211|Alphaproteobacteria	S	Belongs to the UPF0337 (CsbD) family	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
SHD3_k127_2195719_5	1192034.CAP_5657	2.128e-30	129.0	2B9U8@1|root,32374@2|Bacteria,1QAN8@1224|Proteobacteria,4356P@68525|delta/epsilon subdivisions,2X968@28221|Deltaproteobacteria,2Z26H@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2195719_7	1192034.CAP_6099	9.973e-07	61.0	2AH4I@1|root,317E5@2|Bacteria,1PYQB@1224|Proteobacteria,435HF@68525|delta/epsilon subdivisions,2X99V@28221|Deltaproteobacteria,2Z2T7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2196865_2	1254432.SCE1572_09125	2.875e-33	138.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
SHD3_k127_2196865_1	1463901.JOIY01000008_gene2792	1.94e-83	293.0	COG3250@1|root,COG5297@1|root,COG3250@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,ArabFuran-catal,RicinB_lectin_2
SHD3_k127_2196865_0	394503.Ccel_1237	5.752e-139	457.0	COG3345@1|root,COG3345@2|Bacteria,1U52C@1239|Firmicutes,25FA2@186801|Clostridia,36EVC@31979|Clostridiaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	CBM_6,Dockerin_1,Melibiase_2,Melibiase_2_C
SHD3_k127_2196865_3	755731.Clo1100_0917	7.913e-15	76.0	COG3345@1|root,COG3345@2|Bacteria,1U52C@1239|Firmicutes,25FA2@186801|Clostridia,36EVC@31979|Clostridiaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	CBM_6,Dockerin_1,Melibiase_2,Melibiase_2_C
SHD3_k127_2197058_2	483219.LILAB_07765	1.571e-57	217.0	COG0784@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WKB1@28221|Deltaproteobacteria,2Z2WE@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS,PAS_3,PAS_4,Response_reg
SHD3_k127_2197058_3	1192034.CAP_2183	1.704e-35	137.0	COG0261@1|root,COG0261@2|Bacteria,1MZEW@1224|Proteobacteria,42SGM@68525|delta/epsilon subdivisions,2WQ3I@28221|Deltaproteobacteria,2YVHC@29|Myxococcales	28221|Deltaproteobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
SHD3_k127_2197058_4	448385.sce7921	5.272e-30	123.0	COG0211@1|root,COG0211@2|Bacteria,1MZGH@1224|Proteobacteria,42THK@68525|delta/epsilon subdivisions,2WQ2U@28221|Deltaproteobacteria,2YVJI@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
SHD3_k127_2197058_1	448385.sce7920	1.339e-62	226.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
SHD3_k127_2197058_0	1192034.CAP_7398	3.169e-68	241.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2YU35@29|Myxococcales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SHD3_k127_2197058_5	215803.DB30_1844	7.223e-12	70.0	COG1629@1|root,COG4771@2|Bacteria,1MW4X@1224|Proteobacteria,439J9@68525|delta/epsilon subdivisions,2X4VV@28221|Deltaproteobacteria,2YZQ2@29|Myxococcales	28221|Deltaproteobacteria	P	Carboxypeptidase regulatory-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SHD3_k127_2200636_1	1150864.MILUP08_40688	2.111e-141	452.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria	201174|Actinobacteria	Q	Poly(3-hydroxybutyrate) depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_2200636_0	1291050.JAGE01000001_gene594	1.206e-158	518.0	COG3507@1|root,COG3507@2|Bacteria,1TR04@1239|Firmicutes,24ATC@186801|Clostridia,3WG7I@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.55	ko:K15921	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43	-	AbfB,Big_3,CBM_2,CBM_4_9,CBM_6,Dockerin_1,Esterase,Glyco_hydro_43,RicinB_lectin_2
SHD3_k127_2200636_2	1382359.JIAL01000001_gene78	2.998e-32	137.0	COG1917@1|root,COG2169@1|root,COG1917@2|Bacteria,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.2.2.21	ko:K02099,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,AraC_binding,Cupin_2,Endonuclea_NS_2,HTH_18,HTH_AraC
SHD3_k127_2201938_4	1185876.BN8_01787	3.54e-70	255.0	COG3227@1|root,COG3405@1|root,COG3534@1|root,COG3227@2|Bacteria,COG3405@2|Bacteria,COG3534@2|Bacteria	2|Bacteria	G	alpha-L-arabinofuranosidase	-	-	2.4.1.12,3.2.1.156,3.2.1.4	ko:K00694,ko:K15531,ko:K20542	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GH8,GT2	-	Dockerin_1,Glyco_hydro_8,fn3
SHD3_k127_2201938_0	768706.Desor_3288	3.197e-200	654.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,2602D@186807|Peptococcaceae	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SHD3_k127_2201938_1	1192034.CAP_4882	3.545e-110	366.0	COG1989@1|root,COG1989@2|Bacteria,1MUZF@1224|Proteobacteria,42S2A@68525|delta/epsilon subdivisions,2WMQ8@28221|Deltaproteobacteria,2YVME@29|Myxococcales	28221|Deltaproteobacteria	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
SHD3_k127_2201938_2	1254432.SCE1572_46745	1.457e-94	327.0	COG2890@1|root,COG2890@2|Bacteria,1MXCQ@1224|Proteobacteria,42PKA@68525|delta/epsilon subdivisions,2WNH0@28221|Deltaproteobacteria,2YVC9@29|Myxococcales	28221|Deltaproteobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
SHD3_k127_2201938_3	1242864.D187_008833	2.384e-77	265.0	COG0642@1|root,COG2205@2|Bacteria,1N9SU@1224|Proteobacteria,43BZY@68525|delta/epsilon subdivisions,2X39W@28221|Deltaproteobacteria,2YV13@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_2203281_9	1297742.A176_07461	3.265e-32	138.0	COG1595@1|root,COG1595@2|Bacteria,1Q2GH@1224|Proteobacteria,43830@68525|delta/epsilon subdivisions,2X0DG@28221|Deltaproteobacteria,2YVH2@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-binding regulatory protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_2203281_2	378806.STAUR_5520	1.364e-67	251.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42VSC@68525|delta/epsilon subdivisions,2WVIT@28221|Deltaproteobacteria,2YXX0@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_2203281_16	448385.sce4950	0.0001414	53.0	COG1470@1|root,COG1470@2|Bacteria,1Q9IM@1224|Proteobacteria,434EQ@68525|delta/epsilon subdivisions,2WYS3@28221|Deltaproteobacteria,2Z0GH@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SHD3_k127_2203281_8	1254432.SCE1572_13580	3.116e-40	158.0	297PQ@1|root,2ZUWM@2|Bacteria,1PYGM@1224|Proteobacteria,435C6@68525|delta/epsilon subdivisions,2WZPR@28221|Deltaproteobacteria,2Z2HB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2203281_6	706587.Desti_1110	1.744e-46	175.0	COG2227@1|root,COG2227@2|Bacteria,1RIMR@1224|Proteobacteria,43CQM@68525|delta/epsilon subdivisions,2X7Y3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2203281_10	903818.KI912268_gene1837	2.082e-21	103.0	COG1309@1|root,COG1309@2|Bacteria,3Y4KW@57723|Acidobacteria	57723|Acidobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_2203281_0	290397.Adeh_3183	7.301e-105	366.0	2DPRW@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,3334N@2|Bacteria,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
SHD3_k127_2203281_13	204669.Acid345_3007	9.507e-12	78.0	COG1409@1|root,COG1409@2|Bacteria,3Y5PM@57723|Acidobacteria,2JN3H@204432|Acidobacteriia	204432|Acidobacteriia	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SHD3_k127_2203281_7	448385.sce5198	1.766e-41	172.0	COG1609@1|root,COG2208@1|root,COG1609@2|Bacteria,COG2208@2|Bacteria,1RHRV@1224|Proteobacteria,43ARR@68525|delta/epsilon subdivisions,2X65U@28221|Deltaproteobacteria,2Z0U1@29|Myxococcales	28221|Deltaproteobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3,SpoIIE
SHD3_k127_2203281_14	446462.Amir_1954	1.893e-07	64.0	28JV8@1|root,2Z9K7@2|Bacteria,2I533@201174|Actinobacteria,4DZQH@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2203281_1	502025.Hoch_6606	9.592e-77	271.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_2203281_5	448385.sce5034	3.218e-47	175.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_2203281_12	1254432.SCE1572_30610	3.178e-13	79.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	TPR_16,TPR_6,YfiO
SHD3_k127_2203281_3	349521.HCH_06576	6.06e-55	205.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16,HemolysinCabind
SHD3_k127_2203281_4	446462.Amir_6912	1.817e-47	189.0	COG2273@1|root,COG2273@2|Bacteria,2IDDZ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SHD3_k127_2211286_2	1192034.CAP_3011	1.388e-116	388.0	COG3852@1|root,COG3852@2|Bacteria,1QVPN@1224|Proteobacteria,42PS3@68525|delta/epsilon subdivisions,2X7MQ@28221|Deltaproteobacteria,2YVCB@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02668	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,HisKA,PAS,PAS_8
SHD3_k127_2211286_0	448385.sce6250	4.275e-173	551.0	COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,42NES@68525|delta/epsilon subdivisions,2WJ0V@28221|Deltaproteobacteria,2YU38@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretion system (T2SS), protein F	pilC	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
SHD3_k127_2211286_4	1254432.SCE1572_37550	7.969e-85	296.0	COG1680@1|root,COG1680@2|Bacteria,1QUYZ@1224|Proteobacteria,42PUC@68525|delta/epsilon subdivisions,2WK0V@28221|Deltaproteobacteria,2YVFK@29|Myxococcales	28221|Deltaproteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SHD3_k127_2211286_3	1192034.CAP_2243	7.731e-93	323.0	COG1716@1|root,COG1716@2|Bacteria,1N5QD@1224|Proteobacteria,4382E@68525|delta/epsilon subdivisions,2X3CH@28221|Deltaproteobacteria,2YVEM@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_2211286_1	1192034.CAP_2242	5.717e-130	434.0	COG2755@1|root,COG2755@2|Bacteria,1MXSG@1224|Proteobacteria,43476@68525|delta/epsilon subdivisions,2X9U4@28221|Deltaproteobacteria,2YV4A@29|Myxococcales	28221|Deltaproteobacteria	E	COG2755 Lysophospholipase L1 and related esterases	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_2211286_5	1192034.CAP_0426	2.532e-43	168.0	COG2755@1|root,COG2755@2|Bacteria,1MXSG@1224|Proteobacteria,42PM9@68525|delta/epsilon subdivisions,2WZ79@28221|Deltaproteobacteria,2Z1H8@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_2216125_1	59374.Fisuc_0362	6.206e-27	115.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	yjeA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,DUF4163,Glyco_hydro_11,Polysacc_deac_1
SHD3_k127_2216125_2	326427.Cagg_0668	2.508e-16	82.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_2216125_0	1122603.ATVI01000006_gene613	1.036e-42	165.0	COG0625@1|root,COG0625@2|Bacteria,1REDI@1224|Proteobacteria,1S13N@1236|Gammaproteobacteria,1X4XE@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the GST superfamily	gst5	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_N,GST_N_3
SHD3_k127_2216125_3	1297742.A176_05885	1.043e-05	51.0	COG0023@1|root,COG0023@2|Bacteria	2|Bacteria	J	translation initiation factor activity	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SHD3_k127_2217727_3	484770.UFO1_3386	5.848e-50	191.0	COG2132@1|root,COG2132@2|Bacteria,1TQSU@1239|Firmicutes,4H63B@909932|Negativicutes	909932|Negativicutes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SHD3_k127_2217727_5	1408813.AYMG01000010_gene491	5.799e-15	78.0	COG4914@1|root,COG4914@2|Bacteria,4NTQ4@976|Bacteroidetes,1ITBS@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SHD3_k127_2217727_6	649638.Trad_1754	6.612e-12	71.0	COG4914@1|root,COG4914@2|Bacteria,1WNGG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2217727_4	1192034.CAP_2886	1.309e-40	154.0	COG0443@1|root,COG0443@2|Bacteria	2|Bacteria	O	unfolded protein binding	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SHD3_k127_2217727_0	290397.Adeh_0696	2.241e-158	521.0	COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,42M5E@68525|delta/epsilon subdivisions,2WIV6@28221|Deltaproteobacteria,2YTXT@29|Myxococcales	28221|Deltaproteobacteria	J	Ribonuclease E/G family	cafA	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1
SHD3_k127_2217727_2	502025.Hoch_5692	2.384e-60	216.0	COG3298@1|root,COG3298@2|Bacteria,1MVZJ@1224|Proteobacteria,42NY0@68525|delta/epsilon subdivisions,2X3G8@28221|Deltaproteobacteria,2YVYR@29|Myxococcales	28221|Deltaproteobacteria	L	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB	-	-	-	ko:K07501	-	-	-	-	ko00000	-	-	-	DNA_pol_B_exo2
SHD3_k127_2217727_1	1254432.SCE1572_42260	4.594e-87	292.0	COG0787@1|root,COG0787@2|Bacteria,1MV0Q@1224|Proteobacteria,42MGU@68525|delta/epsilon subdivisions,2WIVG@28221|Deltaproteobacteria,2YZJS@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
SHD3_k127_2219029_7	269799.Gmet_1569	9.624e-12	79.0	COG1310@1|root,COG1310@2|Bacteria,1N3TI@1224|Proteobacteria,42TY4@68525|delta/epsilon subdivisions,2WW9Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SMART Mov34 MPN PAD-1 family protein	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
SHD3_k127_2219029_1	748449.Halha_2341	2.529e-153	513.0	COG0155@1|root,COG0425@1|root,COG0155@2|Bacteria,COG0425@2|Bacteria,1TS58@1239|Firmicutes,248DQ@186801|Clostridia	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	nirA	-	1.7.7.1,1.8.7.1	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00531	R00790,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr,TusA
SHD3_k127_2219029_3	370438.PTH_0247	5.317e-121	398.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,260EI@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SHD3_k127_2219029_5	404589.Anae109_3603	1.007e-70	247.0	COG0007@1|root,COG1648@1|root,COG0007@2|Bacteria,COG1648@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WTQ2@28221|Deltaproteobacteria,2Z2X5@29|Myxococcales	28221|Deltaproteobacteria	H	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme	-	-	1.3.1.76,2.1.1.107,4.99.1.4	ko:K02302	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03194,R03947	RC00003,RC00871,RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_binding_7,TP_methylase
SHD3_k127_2219029_6	1442598.JABW01000026_gene1195	8.663e-23	104.0	COG3205@1|root,COG3205@2|Bacteria,1NA8W@1224|Proteobacteria,42W08@68525|delta/epsilon subdivisions,2YQND@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Predicted membrane protein (DUF2061)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2061
SHD3_k127_2219029_4	1408473.JHXO01000013_gene531	2.887e-80	276.0	COG0175@1|root,COG0175@2|Bacteria,4NGVI@976|Bacteroidetes,2FPGR@200643|Bacteroidia	976|Bacteroidetes	EH	Reduction of activated sulfate into sulfite	cysH	-	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SHD3_k127_2219029_2	1291050.JAGE01000002_gene3615	1.188e-152	488.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3WJJK@541000|Ruminococcaceae	186801|Clostridia	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
SHD3_k127_2219029_0	720554.Clocl_3417	3.976e-168	547.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,1TQXK@1239|Firmicutes,25EK3@186801|Clostridia,3WISI@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	-	2.7.1.25,2.7.7.4	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D3
SHD3_k127_2221078_7	379066.GAU_2950	8.801e-05	57.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria	2|Bacteria	K	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12
SHD3_k127_2221078_0	290397.Adeh_3062	4.374e-112	404.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_2221078_5	324602.Caur_1689	7.987e-12	75.0	COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia	32061|Chloroflexia	S	Domain of unknown function (DUF333)	-	-	-	ko:K14475	ko05143,map05143	-	-	-	ko00000,ko00001	-	-	-	DUF333
SHD3_k127_2221078_6	1356852.N008_02650	4.09e-07	62.0	COG2885@1|root,COG3509@1|root,COG2885@2|Bacteria,COG3509@2|Bacteria,4NEND@976|Bacteroidetes,47MW3@768503|Cytophagia	976|Bacteroidetes	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA,PD40,RicinB_lectin_2
SHD3_k127_2221078_3	290397.Adeh_0078	3.683e-30	132.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2221078_2	1254432.SCE1572_14625	1.16e-46	179.0	COG3103@1|root,COG3103@2|Bacteria	2|Bacteria	T	Sh3 type 3 domain protein	-	-	3.2.1.17,3.4.17.14	ko:K01185,ko:K07184,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	SH3_3,VanY
SHD3_k127_2221078_1	1192034.CAP_1186	5.113e-56	199.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_1186|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2223820_1	1254432.SCE1572_20600	1.348e-16	94.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_2223820_0	765952.PUV_06410	8.386e-191	610.0	COG0423@1|root,COG0423@2|Bacteria	2|Bacteria	J	glycyl-tRNA aminoacylation	glyQS	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iSB619.SA_RS07880	HGTP_anticodon,tRNA-synt_2b
SHD3_k127_2226056_8	243090.RB2394	6.494e-10	66.0	COG1102@1|root,COG1102@2|Bacteria,2J0M2@203682|Planctomycetes	203682|Planctomycetes	F	Cytidylate kinase-like family	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
SHD3_k127_2226056_6	1254432.SCE1572_43940	1.017e-62	226.0	28T75@1|root,2ZFFV@2|Bacteria,1RBYB@1224|Proteobacteria,43DNG@68525|delta/epsilon subdivisions,2X6JU@28221|Deltaproteobacteria,2Z10T@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2226056_9	1283299.AUKG01000001_gene2898	3.299e-05	53.0	2AVZ3@1|root,31MTC@2|Bacteria,2HQFU@201174|Actinobacteria,4CS0V@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2226056_1	1192034.CAP_3337	8.938e-125	409.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,42MY5@68525|delta/epsilon subdivisions,2WKST@28221|Deltaproteobacteria,2YUHP@29|Myxococcales	28221|Deltaproteobacteria	E	succinyl-diaminopimelate desuccinylase	dapE2	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SHD3_k127_2226056_0	1192034.CAP_3742	1.799e-238	743.0	COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,42M56@68525|delta/epsilon subdivisions,2WJ8W@28221|Deltaproteobacteria,2YYDJ@29|Myxococcales	28221|Deltaproteobacteria	C	Isocitrate/isopropylmalate dehydrogenase	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SHD3_k127_2226056_2	1192034.CAP_3017	2.615e-77	287.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_2226056_3	1254432.SCE1572_27305	1.504e-71	260.0	COG3215@1|root,COG3215@2|Bacteria,1QR4G@1224|Proteobacteria,4352F@68525|delta/epsilon subdivisions,2WZDD@28221|Deltaproteobacteria,2Z1W5@29|Myxococcales	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SHD3_k127_2226056_4	1254432.SCE1572_45460	9.452e-69	245.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
SHD3_k127_2226056_5	448385.sce7997	1.422e-64	228.0	COG0491@1|root,COG0491@2|Bacteria,1MU8Q@1224|Proteobacteria,42QST@68525|delta/epsilon subdivisions,2WMN8@28221|Deltaproteobacteria,2YZ74@29|Myxococcales	28221|Deltaproteobacteria	S	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	gloB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	HAGH_C,Lactamase_B
SHD3_k127_2228193_11	1278073.MYSTI_00976	7.237e-36	141.0	COG0609@1|root,COG0609@2|Bacteria,1MV9W@1224|Proteobacteria	1224|Proteobacteria	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
SHD3_k127_2228193_7	1278073.MYSTI_00975	2.053e-66	239.0	COG1120@1|root,COG1120@2|Bacteria,1MUNG@1224|Proteobacteria,42P8N@68525|delta/epsilon subdivisions,2WIWA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	HP	PFAM ABC transporter related	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
SHD3_k127_2228193_8	1144275.COCOR_03739	3.466e-54	205.0	COG0614@1|root,COG0614@2|Bacteria,1MWVF@1224|Proteobacteria,42SMM@68525|delta/epsilon subdivisions	1224|Proteobacteria	P	Periplasmic binding protein	chuD	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
SHD3_k127_2228193_4	1254432.SCE1572_42750	4.74e-126	417.0	COG0515@1|root,COG0515@2|Bacteria,1PEGQ@1224|Proteobacteria,434JQ@68525|delta/epsilon subdivisions,2WYWY@28221|Deltaproteobacteria,2Z0U3@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_2228193_0	7425.NV11337-PA	1.81e-265	845.0	COG0058@1|root,KOG2099@2759|Eukaryota,38F0I@33154|Opisthokonta,3BD45@33208|Metazoa,3CSQ6@33213|Bilateria,41WXF@6656|Arthropoda,3SHWJ@50557|Insecta,46EHU@7399|Hymenoptera	33208|Metazoa	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	PYGB	GO:0000166,GO:0000272,GO:0000323,GO:0001666,GO:0001775,GO:0002054,GO:0002060,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005515,GO:0005524,GO:0005536,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0005981,GO:0006015,GO:0006073,GO:0006091,GO:0006109,GO:0006112,GO:0006793,GO:0006796,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006887,GO:0006950,GO:0006955,GO:0007275,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0008219,GO:0008340,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009628,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010033,GO:0010243,GO:0010259,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0012501,GO:0012505,GO:0014070,GO:0014074,GO:0015980,GO:0016052,GO:0016192,GO:0016208,GO:0016528,GO:0016529,GO:0016740,GO:0016757,GO:0016758,GO:0017076,GO:0019222,GO:0019637,GO:0019693,GO:0019725,GO:0019842,GO:0030003,GO:0030016,GO:0030017,GO:0030018,GO:0030141,GO:0030170,GO:0030246,GO:0030424,GO:0030554,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031406,GO:0031410,GO:0031674,GO:0031974,GO:0031982,GO:0031983,GO:0032052,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032881,GO:0032940,GO:0032991,GO:0033293,GO:0033500,GO:0034774,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0036293,GO:0042119,GO:0042221,GO:0042582,GO:0042592,GO:0042593,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043299,GO:0043312,GO:0043467,GO:0043470,GO:0043471,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0045055,GO:0045321,GO:0045819,GO:0045913,GO:0046390,GO:0046391,GO:0046683,GO:0046903,GO:0046983,GO:0048029,GO:0048037,GO:0048518,GO:0048522,GO:0048856,GO:0048878,GO:0050662,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051591,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055114,GO:0060205,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070265,GO:0070266,GO:0070279,GO:0070482,GO:0070873,GO:0070875,GO:0071704,GO:0072503,GO:0072507,GO:0080090,GO:0090407,GO:0097159,GO:0097300,GO:0097367,GO:0097458,GO:0097708,GO:0098723,GO:0098771,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0101002,GO:0120025,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901575,GO:1901576,GO:1901698,GO:1901700,GO:1904813	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
SHD3_k127_2228193_1	316057.RPD_1751	1.276e-201	651.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,2TVEK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SHD3_k127_2228193_10	391625.PPSIR1_09016	2.037e-36	147.0	COG1994@1|root,COG1994@2|Bacteria,1PI96@1224|Proteobacteria,43A6G@68525|delta/epsilon subdivisions,2X25Z@28221|Deltaproteobacteria,2Z1TG@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SHD3_k127_2228193_6	448385.sce7890	2.161e-70	256.0	COG0515@1|root,COG0515@2|Bacteria,1PFJ6@1224|Proteobacteria,4340Z@68525|delta/epsilon subdivisions,2X4J2@28221|Deltaproteobacteria,2YZ45@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_2228193_5	1192034.CAP_0441	2.56e-78	284.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_0441|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2228193_9	1192034.CAP_3356	4.595e-42	178.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_3356|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2228193_3	555779.Dthio_PD3715	1.115e-130	430.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,42MFI@68525|delta/epsilon subdivisions,2WKXD@28221|Deltaproteobacteria,2MAH6@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SHD3_k127_2239764_2	448385.sce8707	6.085e-51	199.0	COG0642@1|root,COG2205@2|Bacteria	448385.sce8707|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2239764_4	395495.Lcho_1565	2.701e-36	143.0	COG3744@1|root,COG3744@2|Bacteria,1NA89@1224|Proteobacteria,2VWUQ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_2239764_5	66869.JNXG01000019_gene1487	3.432e-19	89.0	COG4118@1|root,COG4118@2|Bacteria,2IQGB@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SHD3_k127_2239764_3	1183438.GKIL_3110	1.799e-41	163.0	2AN1K@1|root,31CYZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
SHD3_k127_2239764_8	644283.Micau_6014	1.673e-06	58.0	2AN1K@1|root,31CYZ@2|Bacteria,2I8YS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_8
SHD3_k127_2239764_1	479432.Sros_0604	4.58e-66	238.0	COG4861@1|root,COG4861@2|Bacteria,2GMDQ@201174|Actinobacteria	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_2,HTH_IclR
SHD3_k127_2239764_0	1242864.D187_008442	2.096e-137	454.0	2DP8S@1|root,3311S@2|Bacteria,1PXX1@1224|Proteobacteria,4393N@68525|delta/epsilon subdivisions,2X49K@28221|Deltaproteobacteria,2YYJH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2239764_6	1121406.JAEX01000021_gene1453	2.465e-16	93.0	COG0457@1|root,COG1032@1|root,COG0457@2|Bacteria,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM,TPR_1
SHD3_k127_2242693_5	448385.sce4033	7.374e-74	259.0	2AJ10@1|root,319J4@2|Bacteria,1Q2X4@1224|Proteobacteria,438K5@68525|delta/epsilon subdivisions,2X3UQ@28221|Deltaproteobacteria,2YX5Z@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2242693_9	1123242.JH636434_gene4709	1.136e-23	104.0	COG0724@1|root,COG0724@2|Bacteria,2IZPY@203682|Planctomycetes	203682|Planctomycetes	S	PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SHD3_k127_2242693_4	1254432.SCE1572_46570	3.281e-82	288.0	COG0318@1|root,COG0318@2|Bacteria,1QXPD@1224|Proteobacteria,43C59@68525|delta/epsilon subdivisions,2WRV5@28221|Deltaproteobacteria,2Z0SY@29|Myxococcales	28221|Deltaproteobacteria	IQ	Acyl-protein synthetase, LuxE	-	-	-	-	-	-	-	-	-	-	-	-	LuxE
SHD3_k127_2242693_1	448385.sce8625	5.631e-129	426.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,2YWB2@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SHD3_k127_2242693_0	448385.sce8626	6.9e-137	441.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2YWRT@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SHD3_k127_2242693_2	448385.sce1459	9.079e-124	418.0	COG0249@1|root,COG0249@2|Bacteria,1N9K4@1224|Proteobacteria,42ZN5@68525|delta/epsilon subdivisions,2WUW7@28221|Deltaproteobacteria,2YTSE@29|Myxococcales	28221|Deltaproteobacteria	L	ATPase domain of DNA mismatch repair MUTS family	-	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
SHD3_k127_2242693_3	292459.STH1541	2.413e-85	295.0	COG2201@1|root,COG2201@2|Bacteria,1TRHC@1239|Firmicutes,249FD@186801|Clostridia	186801|Clostridia	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SHD3_k127_2242693_6	666509.RCA23_c11590	6.682e-62	235.0	COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria	2|Bacteria	T	Pfam Adenylate and Guanylate cyclase catalytic domain	cyaD	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,Fer2,GAF,GAF_2,Guanylate_cyc,Pkinase,Response_reg
SHD3_k127_2257010_8	1179773.BN6_41910	2.145e-06	61.0	COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria,4E7NA@85010|Pseudonocardiales	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2257010_10	1463900.JOIX01000001_gene6449	0.0001816	54.0	COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria	201174|Actinobacteria	K	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2257010_7	344747.PM8797T_00177	1.567e-29	134.0	2ESRG@1|root,33K9V@2|Bacteria,2J33K@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2257010_9	379066.GAU_3595	5.52e-05	55.0	COG4447@1|root,COG4447@2|Bacteria,1ZT1T@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Sortilin, neurotensin receptor 3,	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SHD3_k127_2257010_2	426117.M446_6784	6.7e-121	401.0	COG2271@1|root,COG2271@2|Bacteria,1MUEK@1224|Proteobacteria,2TS60@28211|Alphaproteobacteria,1JU1S@119045|Methylobacteriaceae	28211|Alphaproteobacteria	G	PFAM major facilitator superfamily MFS_1	-	-	-	ko:K13021	-	-	-	-	ko00000,ko02000	2.A.1.14.3	-	-	MFS_1
SHD3_k127_2257010_5	1056820.KB900661_gene3918	1.652e-72	258.0	COG2755@1|root,COG2755@2|Bacteria,1N3FB@1224|Proteobacteria,1RW9E@1236|Gammaproteobacteria,2PPTD@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Lipase_GDSL_2
SHD3_k127_2257010_0	1089547.KB913013_gene4597	9.452e-138	479.0	COG0784@1|root,COG2203@1|root,COG3829@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG5002@2|Bacteria,4PM0I@976|Bacteroidetes,47XEX@768503|Cytophagia	976|Bacteroidetes	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
SHD3_k127_2257010_6	234267.Acid_6266	3.195e-67	234.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_2
SHD3_k127_2257010_3	1121918.ARWE01000001_gene3108	3.824e-93	312.0	COG0580@1|root,COG0580@2|Bacteria,1MZ47@1224|Proteobacteria	1224|Proteobacteria	U	Belongs to the MIP aquaporin (TC 1.A.8) family	-	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
SHD3_k127_2257010_1	555079.Toce_1732	1.188e-130	444.0	COG3408@1|root,COG3408@2|Bacteria,1TPX8@1239|Firmicutes,249BI@186801|Clostridia,42FGZ@68295|Thermoanaerobacterales	186801|Clostridia	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SHD3_k127_2257010_4	290397.Adeh_2660	3.793e-77	266.0	COG4221@1|root,COG4221@2|Bacteria,1MUU6@1224|Proteobacteria,42YQ8@68525|delta/epsilon subdivisions,2WU8K@28221|Deltaproteobacteria,2YZNE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_2263424_4	1192034.CAP_3958	6.657e-13	78.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_2263424_2	402881.Plav_0855	3.192e-43	171.0	COG0702@1|root,COG0702@2|Bacteria,1MZG7@1224|Proteobacteria,2UBX1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	GM	Nucleoside-diphosphate-sugar epimerases	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SHD3_k127_2263424_0	194439.CT0498	5.079e-184	589.0	COG0004@1|root,COG0004@2|Bacteria,1FDC2@1090|Chlorobi	2|Bacteria	P	PFAM Rh family protein ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SHD3_k127_2263424_1	935567.JAES01000002_gene681	2.087e-118	387.0	COG3384@1|root,COG3384@2|Bacteria,1MXJZ@1224|Proteobacteria,1RR5P@1236|Gammaproteobacteria,1X5FC@135614|Xanthomonadales	135614|Xanthomonadales	S	Extradiol ring-cleavage dioxygenase	-	-	-	ko:K15777	ko00965,map00965	-	R08836	RC00387	ko00000,ko00001,ko01000	-	-	-	LigB
SHD3_k127_2263424_3	502025.Hoch_0984	2.108e-27	113.0	COG1506@1|root,COG1506@2|Bacteria,1R0DH@1224|Proteobacteria,43CWV@68525|delta/epsilon subdivisions,2X84T@28221|Deltaproteobacteria,2Z3KY@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PPC
SHD3_k127_2270512_4	713587.THITH_13230	1.741e-31	129.0	COG2518@1|root,COG2518@2|Bacteria,1MXQC@1224|Proteobacteria,1S2WI@1236|Gammaproteobacteria,1WY40@135613|Chromatiales	135613|Chromatiales	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SHD3_k127_2270512_0	502025.Hoch_6075	6.71e-145	475.0	COG1004@1|root,COG1004@2|Bacteria,1MW5U@1224|Proteobacteria,42MDV@68525|delta/epsilon subdivisions,2WJ3T@28221|Deltaproteobacteria,2YTZC@29|Myxococcales	28221|Deltaproteobacteria	C	UDP binding domain	ugd	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
SHD3_k127_2270512_1	290397.Adeh_0828	1.555e-62	219.0	COG2077@1|root,COG2077@2|Bacteria,1RAJ9@1224|Proteobacteria,42RE8@68525|delta/epsilon subdivisions,2WNA5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides	tpx	-	1.11.1.15	ko:K11065	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA,Redoxin
SHD3_k127_2270512_2	1396141.BATP01000023_gene598	2.301e-46	170.0	COG0662@1|root,COG0662@2|Bacteria,46W1W@74201|Verrucomicrobia,2IW0F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2270512_3	215803.DB30_2185	3.152e-35	143.0	COG2271@1|root,COG2271@2|Bacteria,1MWYR@1224|Proteobacteria,42RD4@68525|delta/epsilon subdivisions,2WN11@28221|Deltaproteobacteria,2YU83@29|Myxococcales	28221|Deltaproteobacteria	G	Organic Anion Transporter Polypeptide (OATP) family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SHD3_k127_2272669_4	1254432.SCE1572_40490	3.905e-36	137.0	COG0539@1|root,COG2183@1|root,COG0539@2|Bacteria,COG2183@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SHD3_k127_2272669_0	1192034.CAP_7597	7.827e-208	651.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SHD3_k127_2272669_3	502025.Hoch_2380	4.061e-57	213.0	COG0283@1|root,COG0283@2|Bacteria,1MUUD@1224|Proteobacteria,42STI@68525|delta/epsilon subdivisions,2WP1K@28221|Deltaproteobacteria,2Z2XF@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
SHD3_k127_2272669_1	448385.sce8915	2.116e-155	498.0	COG0079@1|root,COG0079@2|Bacteria,1MW7I@1224|Proteobacteria,42NCH@68525|delta/epsilon subdivisions,2WJDR@28221|Deltaproteobacteria,2YUC9@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SHD3_k127_2289026_4	1121288.AULL01000012_gene468	4.147e-09	63.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia,3ZPIW@59732|Chryseobacterium	976|Bacteroidetes	Q	Multicopper oxidase	copA	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
SHD3_k127_2289026_5	321846.PS417_00925	1.224e-06	55.0	COG5583@1|root,COG5583@2|Bacteria,1NGI6@1224|Proteobacteria	1224|Proteobacteria	S	Small protein	HA62_30270	-	-	-	-	-	-	-	-	-	-	-	DUF2292
SHD3_k127_2289026_3	1192034.CAP_1809	3.963e-25	121.0	COG3746@1|root,COG3746@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SHD3_k127_2289026_0	1408254.T458_01280	2.362e-145	482.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,4HD5R@91061|Bacilli,26S1S@186822|Paenibacillaceae	91061|Bacilli	P	Sulfate transporter subunit	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
SHD3_k127_2289026_1	1242864.D187_001217	4.487e-106	353.0	COG0555@1|root,COG0555@2|Bacteria,1QTTU@1224|Proteobacteria,42NRU@68525|delta/epsilon subdivisions,2X7CC@28221|Deltaproteobacteria,2YWGP@29|Myxococcales	28221|Deltaproteobacteria	P	Binding-protein-dependent transport system inner membrane component	cysU	-	-	ko:K02046	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SHD3_k127_2289026_2	266834.SM_b21131	4.081e-92	327.0	COG4208@1|root,COG4208@2|Bacteria,1MV8X@1224|Proteobacteria,2TQR8@28211|Alphaproteobacteria,4BA56@82115|Rhizobiaceae	28211|Alphaproteobacteria	P	ABC-type sulfate transport system, permease component	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
SHD3_k127_2296538_0	1382306.JNIM01000001_gene3212	5.865e-92	317.0	COG1129@1|root,COG1129@2|Bacteria,2G7YP@200795|Chloroflexi	200795|Chloroflexi	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SHD3_k127_2296538_1	448385.sce0828	5.468e-66	242.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce0828|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2296538_2	1254432.SCE1572_39600	6.274e-06	59.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_39600|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2299792_3	1078020.KEK_07057	1.033e-43	169.0	COG1028@1|root,COG1028@2|Bacteria,2I45Y@201174|Actinobacteria,233Z9@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0000166,GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008289,GO:0008610,GO:0009058,GO:0009987,GO:0010817,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0036094,GO:0042445,GO:0042446,GO:0042562,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0065007,GO:0065008,GO:0070401,GO:0071704,GO:0097159,GO:0099130,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903924	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_2299792_0	742725.HMPREF9450_01501	9.927e-110	376.0	COG1902@1|root,COG1902@2|Bacteria,4NF98@976|Bacteroidetes,2FNNA@200643|Bacteroidia,22VH1@171550|Rikenellaceae	976|Bacteroidetes	C	NADH:flavin oxidoreductase / NADH oxidase family	namA	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SHD3_k127_2299792_1	290397.Adeh_3532	3.061e-99	346.0	COG0642@1|root,COG2205@2|Bacteria,1QX8G@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,Response_reg
SHD3_k127_2299792_5	1144275.COCOR_05100	6.485e-20	103.0	COG0745@1|root,COG0745@2|Bacteria,1NEVF@1224|Proteobacteria,43C0G@68525|delta/epsilon subdivisions,2WY70@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_2299792_4	1232410.KI421412_gene441	2.058e-27	115.0	COG3809@1|root,COG3809@2|Bacteria,1Q8Z4@1224|Proteobacteria,42UTF@68525|delta/epsilon subdivisions,2WXCZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
SHD3_k127_2299792_2	1120999.JONM01000001_gene1170	5.164e-44	170.0	COG4461@1|root,COG4461@2|Bacteria,1MZPM@1224|Proteobacteria,2WBBU@28216|Betaproteobacteria,2KS9Y@206351|Neisseriales	206351|Neisseriales	G	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_230100_6	474922.ELA34014	6.084e-16	91.0	COG2272@1|root,KOG4389@2759|Eukaryota,38HRZ@33154|Opisthokonta,3P0DZ@4751|Fungi,3QNHX@4890|Ascomycota	4751|Fungi	G	Belongs to the type-B carboxylesterase lipase family	-	-	-	-	-	-	-	-	-	-	-	-	COesterase
SHD3_k127_230100_7	1380356.JNIK01000018_gene839	2.714e-11	76.0	COG5479@1|root,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4EX5K@85013|Frankiales	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
SHD3_k127_230100_3	1254432.SCE1572_50395	2.049e-39	154.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_230100_1	1254432.SCE1572_06270	4.81e-81	293.0	COG5184@1|root,COG5184@2|Bacteria,1PEJQ@1224|Proteobacteria,439SY@68525|delta/epsilon subdivisions,2X560@28221|Deltaproteobacteria,2Z05W@29|Myxococcales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_230100_0	1192034.CAP_8938	6.993e-123	412.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SHD3_k127_230100_2	1254432.SCE1572_27215	2.195e-44	180.0	COG1051@1|root,COG1051@2|Bacteria,1RA9T@1224|Proteobacteria	1224|Proteobacteria	F	NUDIX hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
SHD3_k127_230100_4	391625.PPSIR1_23234	6.196e-38	160.0	COG2304@1|root,COG2304@2|Bacteria,1Q2PD@1224|Proteobacteria,438AP@68525|delta/epsilon subdivisions,2X3K0@28221|Deltaproteobacteria,2YWD7@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2
SHD3_k127_2320097_3	1254432.SCE1572_17770	1.76e-27	125.0	COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria,2YUXH@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SHD3_k127_2320097_5	1502850.FG91_01806	1.425e-06	55.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SHD3_k127_2320097_7	1120705.FG95_03487	0.0003054	51.0	COG1752@1|root,COG1752@2|Bacteria	2|Bacteria	M	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
SHD3_k127_2320097_0	1254432.SCE1572_11400	2.229e-107	363.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria	1224|Proteobacteria	Q	Esterase, phb depolymerase family	phaZ1	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SHD3_k127_2320097_1	439235.Dalk_0842	7.359e-51	202.0	COG0457@1|root,COG0457@2|Bacteria,1RKQQ@1224|Proteobacteria,42T9T@68525|delta/epsilon subdivisions,2WPQ0@28221|Deltaproteobacteria,2MN67@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Tetratricopeptide TPR_2 repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_2320097_6	82654.Pse7367_0512	3.755e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,1G1UY@1117|Cyanobacteria	1117|Cyanobacteria	S	Alternative locus ID	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3,TPR_1,TPR_11,TPR_16,TPR_2,TPR_7,TPR_8
SHD3_k127_2320097_2	931276.Cspa_c32760	7.279e-50	197.0	COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,249YD@186801|Clostridia,36GWD@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.136,3.2.1.45	ko:K01201,ko:K15924	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30,GH5	-	Dockerin_1,Glyco_hydr_30_2,Glyco_hydro_30,Glyco_hydro_30C
SHD3_k127_2320097_4	290397.Adeh_0078	1.052e-22	101.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2320403_8	1296415.JACC01000007_gene2456	8.851e-08	56.0	COG3291@1|root,COG3291@2|Bacteria,4NNHP@976|Bacteroidetes,1I21K@117743|Flavobacteriia,2YHE0@290174|Aquimarina	976|Bacteroidetes	Q	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,VCBS,fn3
SHD3_k127_2320403_9	933262.AXAM01000035_gene2132	1.979e-06	56.0	COG3291@1|root,COG3291@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
SHD3_k127_2320403_2	869210.Marky_0739	1.84e-128	426.0	COG0451@1|root,COG0451@2|Bacteria,1WMCY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SHD3_k127_2320403_3	272134.KB731324_gene1964	2.54e-106	350.0	COG1208@1|root,COG1208@2|Bacteria,1G4AN@1117|Cyanobacteria,1H8TU@1150|Oscillatoriales	1117|Cyanobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.33	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R00956	RC00002	ko00000,ko00001,ko01000	-	-	-	NTP_transferase
SHD3_k127_2320403_5	926566.Terro_2807	5.852e-83	292.0	COG1216@1|root,COG1216@2|Bacteria,3Y7UY@57723|Acidobacteria,2JN0S@204432|Acidobacteriia	204432|Acidobacteriia	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_2320403_4	1162668.LFE_2241	2.212e-91	324.0	COG0394@1|root,COG3919@1|root,COG0394@2|Bacteria,COG3919@2|Bacteria,3J15R@40117|Nitrospirae	40117|Nitrospirae	T	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2320403_6	414684.RC1_3995	4.062e-71	246.0	COG2120@1|root,COG2120@2|Bacteria,1MX2V@1224|Proteobacteria,2TT5F@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
SHD3_k127_2320403_0	251229.Chro_2348	2.647e-175	557.0	COG2227@1|root,COG2227@2|Bacteria,1G06X@1117|Cyanobacteria,3VJGG@52604|Pleurocapsales	1117|Cyanobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SHD3_k127_2320403_7	1123368.AUIS01000027_gene1349	4.406e-63	224.0	COG1898@1|root,COG1898@2|Bacteria,1R9YD@1224|Proteobacteria,1S245@1236|Gammaproteobacteria,2NCIQ@225057|Acidithiobacillales	225057|Acidithiobacillales	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	-	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	dTDP_sugar_isom
SHD3_k127_2320403_1	66897.DJ64_14855	2.547e-168	539.0	COG4310@1|root,COG4310@2|Bacteria,2GK72@201174|Actinobacteria	201174|Actinobacteria	S	winged helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	DUF2172,DUF4910,HTH_47,Peptidase_M28
SHD3_k127_2335381_2	1267535.KB906767_gene61	1.597e-46	174.0	COG1005@1|root,COG1005@2|Bacteria,3Y3VS@57723|Acidobacteria,2JHQZ@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	-	-	-	-	-	-	-	-	-	-	NADHdh
SHD3_k127_2335381_0	1123368.AUIS01000006_gene660	2.918e-320	1003.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,1RMUH@1236|Gammaproteobacteria,2NBWZ@225057|Acidithiobacillales	225057|Acidithiobacillales	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SHD3_k127_2335381_1	323848.Nmul_A1017	2.327e-198	624.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,2VJJ1@28216|Betaproteobacteria,3745P@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
SHD3_k127_2345742_6	1449353.JQMQ01000005_gene1587	1.061e-05	54.0	COG0438@1|root,COG0438@2|Bacteria,2IDF2@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4
SHD3_k127_2345742_4	378806.STAUR_6388	1.5e-36	150.0	COG0328@1|root,COG0328@2|Bacteria,1MZD1@1224|Proteobacteria,42UI6@68525|delta/epsilon subdivisions,2WQSU@28221|Deltaproteobacteria,2YXKN@29|Myxococcales	28221|Deltaproteobacteria	L	Reverse transcriptase-like	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RVT_3
SHD3_k127_2345742_3	596151.DesfrDRAFT_1235	1.92e-45	180.0	COG1533@1|root,COG1533@2|Bacteria,1Q22I@1224|Proteobacteria,42SVJ@68525|delta/epsilon subdivisions,2WPAY@28221|Deltaproteobacteria,2MA2G@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	Domain of unknown function (DUF1848)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1848
SHD3_k127_2345742_5	1303518.CCALI_00619	3.027e-26	126.0	COG3693@1|root,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
SHD3_k127_2345742_0	1087481.AGFX01000047_gene2072	6.751e-113	392.0	COG2730@1|root,COG4124@1|root,COG4733@1|root,COG2730@2|Bacteria,COG4124@2|Bacteria,COG4733@2|Bacteria,1V0UJ@1239|Firmicutes,4HGW4@91061|Bacilli,26T9Y@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 26 family	celA7	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM_3,CBM_35,Glyco_hydro_26,Glyco_hydro_44,fn3
SHD3_k127_2345742_1	661478.OP10G_0793	4.384e-85	295.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	hflC	-	-	-	-	-	-	-	-	-	-	-	Band_7
SHD3_k127_2346810_0	338963.Pcar_2552	4.771e-143	464.0	COG5557@1|root,COG5557@2|Bacteria,1PFX4@1224|Proteobacteria,42PIE@68525|delta/epsilon subdivisions,2WM3C@28221|Deltaproteobacteria,43SBI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Polysulphide reductase, NrfD	moz	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	DUF3341,NrfD
SHD3_k127_2346810_9	338963.Pcar_2553	5.48e-07	58.0	COG2010@1|root,COG2010@2|Bacteria,1PWTD@1224|Proteobacteria,437B9@68525|delta/epsilon subdivisions,2X9ZG@28221|Deltaproteobacteria,43V90@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SHD3_k127_2346810_5	314345.SPV1_03928	1.855e-23	108.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria	1224|Proteobacteria	C	cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SHD3_k127_2346810_6	1191523.MROS_0041	5.013e-18	98.0	COG4531@1|root,COG4531@2|Bacteria	2|Bacteria	P	zinc ion transport	actF	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2346810_8	469383.Cwoe_4928	2.318e-15	83.0	COG2062@1|root,COG2062@2|Bacteria,2HPES@201174|Actinobacteria,4CQT1@84995|Rubrobacteria	84995|Rubrobacteria	T	Phosphoglycerate mutase family	-	-	-	ko:K08296	-	-	-	-	ko00000,ko01000	-	-	-	His_Phos_1
SHD3_k127_2346810_4	335543.Sfum_2366	3.036e-31	135.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ88@28221|Deltaproteobacteria,2MS3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SHD3_k127_2346810_3	96561.Dole_2642	1.038e-38	149.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,2MKAV@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SHD3_k127_2346810_7	44060.JODL01000044_gene3976	8.894e-18	88.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K21886,ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5,MarR_2
SHD3_k127_2346810_1	690850.Desaf_2164	1.203e-75	263.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,42N5I@68525|delta/epsilon subdivisions,2WM5T@28221|Deltaproteobacteria,2M9FV@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	PFAM Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Methyltransf_31,Radical_SAM
SHD3_k127_2346810_2	269799.Gmet_0805	5.288e-60	225.0	COG1853@1|root,COG1853@2|Bacteria,1RAIQ@1224|Proteobacteria,42QXX@68525|delta/epsilon subdivisions,2WMUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SHD3_k127_2350142_3	246197.MXAN_6750	2.152e-07	63.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	csgD	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	GerE,Response_reg
SHD3_k127_2350142_1	889378.Spiaf_2383	7.809e-92	312.0	COG0842@1|root,COG0842@2|Bacteria	2|Bacteria	V	Transport permease protein	nodJ	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SHD3_k127_2350142_0	1307761.L21SP2_2583	6.192e-100	338.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	nodI	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
SHD3_k127_2350142_2	1123060.JONP01000004_gene595	3.173e-20	102.0	COG0681@1|root,COG0681@2|Bacteria,1MXUF@1224|Proteobacteria,2TR9N@28211|Alphaproteobacteria,2JQUC@204441|Rhodospirillales	204441|Rhodospirillales	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
SHD3_k127_2350142_4	219305.MCAG_00228	6.938e-06	57.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4DI53@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 12 (cellulase H) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12
SHD3_k127_2369487_8	1254432.SCE1572_07800	3.796e-83	287.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_2369487_16	1244869.H261_09242	9.058e-22	98.0	COG4118@1|root,COG4118@2|Bacteria,1N7BG@1224|Proteobacteria,2UFRK@28211|Alphaproteobacteria,2JUQG@204441|Rhodospirillales	204441|Rhodospirillales	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SHD3_k127_2369487_15	861299.J421_1642	5.773e-29	124.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_2369487_3	448385.sce1090	2.946e-163	526.0	COG0617@1|root,COG0617@2|Bacteria,1MU2X@1224|Proteobacteria,42N0S@68525|delta/epsilon subdivisions,2WMJK@28221|Deltaproteobacteria,2Z3CT@29|Myxococcales	28221|Deltaproteobacteria	H	tRNA nucleotidyltransferase domain 2 putative	-	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
SHD3_k127_2369487_2	448385.sce7292	2.125e-277	868.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2YUHW@29|Myxococcales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SHD3_k127_2369487_11	1192034.CAP_4571	7.803e-68	240.0	COG0037@1|root,COG0037@2|Bacteria,1MU85@1224|Proteobacteria,42NF0@68525|delta/epsilon subdivisions,2WIJK@28221|Deltaproteobacteria,2YVDX@29|Myxococcales	28221|Deltaproteobacteria	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
SHD3_k127_2369487_4	1254432.SCE1572_42500	2.658e-136	442.0	COG0482@1|root,COG0482@2|Bacteria,1MUT1@1224|Proteobacteria,42MZR@68525|delta/epsilon subdivisions,2WK6B@28221|Deltaproteobacteria,2YUTU@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
SHD3_k127_2369487_0	215803.DB30_8103	0.0	1190.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YYD8@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SHD3_k127_2369487_12	448385.sce8248	2.933e-56	211.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42M4G@68525|delta/epsilon subdivisions,2WKAK@28221|Deltaproteobacteria,2YUR4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SHD3_k127_2369487_1	1123508.JH636439_gene901	2.357e-308	970.0	COG0567@1|root,COG0567@2|Bacteria,2IWRF@203682|Planctomycetes	203682|Planctomycetes	C	Dehydrogenase E1 component	sucA	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
SHD3_k127_2369487_6	886293.Sinac_6537	2.079e-121	401.0	COG0508@1|root,COG0508@2|Bacteria,2IWRM@203682|Planctomycetes	203682|Planctomycetes	C	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)	sucB	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
SHD3_k127_2369487_9	512565.AMIS_65590	5.681e-77	268.0	COG5297@1|root,COG5297@2|Bacteria,2GK3F@201174|Actinobacteria	201174|Actinobacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase,RicinB_lectin_2
SHD3_k127_2369487_17	596154.Alide2_0660	1e-20	99.0	COG0797@1|root,COG0797@2|Bacteria,1MZ8S@1224|Proteobacteria,2VJAN@28216|Betaproteobacteria,4AF8Z@80864|Comamonadaceae	28216|Betaproteobacteria	M	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides	rlpA	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
SHD3_k127_2369487_14	1192034.CAP_0976	2.091e-47	185.0	COG0340@1|root,COG0340@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria,2YVIU@29|Myxococcales	28221|Deltaproteobacteria	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
SHD3_k127_2369487_7	1254432.SCE1572_15415	9.447e-100	332.0	COG0157@1|root,COG0157@2|Bacteria,1MW0C@1224|Proteobacteria,42MY7@68525|delta/epsilon subdivisions,2WJH7@28221|Deltaproteobacteria,2YUYQ@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1988	QRPTase_C,QRPTase_N
SHD3_k127_2369487_10	1192034.CAP_1551	3.292e-76	263.0	COG1266@1|root,COG1266@2|Bacteria,1NHPM@1224|Proteobacteria,4384U@68525|delta/epsilon subdivisions,2X9XI@28221|Deltaproteobacteria,2YVRP@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SHD3_k127_2369487_5	1254432.SCE1572_30705	2.591e-124	419.0	COG1193@1|root,COG1193@2|Bacteria	2|Bacteria	L	negative regulation of DNA recombination	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
SHD3_k127_2381995_0	760568.Desku_0489	7.29e-61	221.0	COG2043@1|root,COG2043@2|Bacteria,1UYUH@1239|Firmicutes,24APQ@186801|Clostridia,260ZZ@186807|Peptococcaceae	186801|Clostridia	S	Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
SHD3_k127_2381995_3	443143.GM18_1183	7.125e-45	177.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,42RF4@68525|delta/epsilon subdivisions,2WPIV@28221|Deltaproteobacteria,43TWB@69541|Desulfuromonadales	28221|Deltaproteobacteria	GK	PFAM ROK family protein	glkA	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
SHD3_k127_2381995_1	1192034.CAP_6421	4.292e-50	188.0	2ENGF@1|root,33G3Y@2|Bacteria,1P8WT@1224|Proteobacteria,43261@68525|delta/epsilon subdivisions,2WXJG@28221|Deltaproteobacteria,2YVTG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2381995_9	644076.SCH4B_1499	0.0008789	47.0	COG5126@1|root,COG5126@2|Bacteria,1NH5D@1224|Proteobacteria,2UF3D@28211|Alphaproteobacteria,4NCBQ@97050|Ruegeria	28211|Alphaproteobacteria	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_1,EF-hand_5
SHD3_k127_2381995_7	1192034.CAP_1983	7.225e-20	100.0	2C2AI@1|root,32RA3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2381995_5	745776.DGo_CA0641	6.183e-29	132.0	COG4251@1|root,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg
SHD3_k127_2381995_2	1192034.CAP_8620	1.396e-45	168.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_2381995_8	448385.sce3783	1.554e-12	75.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_2381995_6	215803.DB30_4062	3.534e-28	123.0	COG2197@1|root,COG2197@2|Bacteria,1PXG3@1224|Proteobacteria,43DU6@68525|delta/epsilon subdivisions,2WYVS@28221|Deltaproteobacteria,2Z0RE@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SHD3_k127_2384738_1	1214101.BN159_1639	1.922e-55	204.0	COG3250@1|root,COG5297@1|root,COG3250@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	AbfB,ArabFuran-catal
SHD3_k127_2384738_0	189426.PODO_07665	1.666e-94	337.0	COG3345@1|root,COG3345@2|Bacteria,1TQ3Q@1239|Firmicutes,4HCAE@91061|Bacilli,26TC5@186822|Paenibacillaceae	91061|Bacilli	G	Alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
SHD3_k127_2384738_2	203119.Cthe_1471	5.006e-54	204.0	COG2730@1|root,COG2730@2|Bacteria,1UTVE@1239|Firmicutes,254HP@186801|Clostridia,3WR4M@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2394439_0	1254432.SCE1572_02165	0.0	3448.0	COG0457@1|root,COG2956@1|root,COG3118@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3118@2|Bacteria,1MVIW@1224|Proteobacteria,4391J@68525|delta/epsilon subdivisions,2X472@28221|Deltaproteobacteria,2YYDY@29|Myxococcales	28221|Deltaproteobacteria	GO	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_7,TPR_8
SHD3_k127_2394439_2	1125863.JAFN01000001_gene3416	1.046e-24	115.0	COG2121@1|root,COG2121@2|Bacteria,1MZID@1224|Proteobacteria,42UW6@68525|delta/epsilon subdivisions,2WQ4A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
SHD3_k127_2394439_1	1192034.CAP_3167	1.219e-80	287.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WQC6@28221|Deltaproteobacteria,2YV64@29|Myxococcales	28221|Deltaproteobacteria	EH	Aminotransferase	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SHD3_k127_2394439_3	1192034.CAP_3164	1.482e-12	79.0	COG3595@1|root,COG3595@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
SHD3_k127_2394926_7	290397.Adeh_3956	2.339e-27	120.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2394926_1	1254432.SCE1572_49820	1.99e-207	660.0	COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,42M8D@68525|delta/epsilon subdivisions,2WJ6E@28221|Deltaproteobacteria,2YWFY@29|Myxococcales	28221|Deltaproteobacteria	C	C-terminal domain of alpha-glycerophosphate oxidase	glpA	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C,Fer2_BFD
SHD3_k127_2394926_0	448385.sce2234	1.343e-254	812.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,1NDMY@1224|Proteobacteria,4333K@68525|delta/epsilon subdivisions,2WXH7@28221|Deltaproteobacteria,2YXQH@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,CelD_N,Glyco_hydro_9
SHD3_k127_2394926_6	868131.MSWAN_0888	7.016e-37	150.0	COG2050@1|root,arCOG00777@2157|Archaea,2XXGC@28890|Euryarchaeota,23PW5@183925|Methanobacteria	183925|Methanobacteria	Q	PFAM Thioesterase superfamily	-	-	-	ko:K02614	ko00360,map00360	-	R09840	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	4HBT
SHD3_k127_2394926_3	502025.Hoch_5024	8.763e-56	223.0	2EV2E@1|root,33NHG@2|Bacteria,1NRHZ@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2394926_2	483219.LILAB_02975	1.374e-125	417.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	frgC	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_2394926_5	448385.sce8901	6.563e-38	151.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_2394926_8	1380391.JIAS01000001_gene2763	3.005e-26	121.0	COG0457@1|root,COG4076@1|root,COG0457@2|Bacteria,COG4076@2|Bacteria,1R46U@1224|Proteobacteria,2U32I@28211|Alphaproteobacteria,2JZQH@204441|Rhodospirillales	204441|Rhodospirillales	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	PrmA,TPR_1,TPR_16,TPR_8
SHD3_k127_2403488_1	1463854.JOHT01000019_gene4850	1.657e-19	104.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
SHD3_k127_241037_1	1254432.SCE1572_46645	1.021e-184	609.0	COG1215@1|root,COG1215@2|Bacteria,1MX08@1224|Proteobacteria,42MS6@68525|delta/epsilon subdivisions,2WIYE@28221|Deltaproteobacteria,2YUMA@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
SHD3_k127_241037_0	1123253.AUBD01000002_gene1229	8.862e-200	653.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1X4KE@135614|Xanthomonadales	135614|Xanthomonadales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SHD3_k127_241037_2	449447.MAE_14020	7.244e-13	73.0	COG2337@1|root,COG2337@2|Bacteria,1G7HN@1117|Cyanobacteria	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SHD3_k127_2417551_0	404589.Anae109_3372	3.145e-12	81.0	COG0457@1|root,COG0457@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
SHD3_k127_2441964_2	1254432.SCE1572_25535	3.712e-62	225.0	COG1577@1|root,COG1577@2|Bacteria,1NBQM@1224|Proteobacteria,43C2T@68525|delta/epsilon subdivisions,2X7DD@28221|Deltaproteobacteria,2YVJ4@29|Myxococcales	28221|Deltaproteobacteria	I	mevalonate kinase	mvk	-	2.7.1.36	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	M00095	R02245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SHD3_k127_2441964_3	448385.sce1762	2.197e-61	227.0	COG2203@1|root,COG2203@2|Bacteria,1P3F7@1224|Proteobacteria,4318K@68525|delta/epsilon subdivisions,2WWQB@28221|Deltaproteobacteria,2Z23F@29|Myxococcales	28221|Deltaproteobacteria	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	GAF_3
SHD3_k127_2441964_1	1254432.SCE1572_10985	1.493e-68	235.0	COG0745@1|root,COG0745@2|Bacteria,1RDNP@1224|Proteobacteria,42RF8@68525|delta/epsilon subdivisions,2WNSP@28221|Deltaproteobacteria,2YVG6@29|Myxococcales	28221|Deltaproteobacteria	T	Chemotaxis protein CheY	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SHD3_k127_2441964_6	760568.Desku_1853	1.321e-40	157.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,2623G@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the TrpF family	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
SHD3_k127_2441964_0	1122915.AUGY01000010_gene4528	1.678e-88	301.0	COG1028@1|root,COG1028@2|Bacteria,1VR43@1239|Firmicutes,4HT9V@91061|Bacilli,26W5D@186822|Paenibacillaceae	91061|Bacilli	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SHD3_k127_2441964_7	448385.sce5231	1.999e-40	166.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_2441964_10	1192034.CAP_8613	2.704e-07	56.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_2441964_5	448385.sce5231	1.241e-40	166.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_2441964_8	448385.sce5231	1.896e-37	155.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_2444010_5	1229204.AMYY01000030_gene713	1.001e-17	90.0	COG0642@1|root,COG2205@2|Bacteria	1229204.AMYY01000030_gene713|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2444010_2	448385.sce3599	3.497e-80	272.0	COG0176@1|root,COG0176@2|Bacteria,1MWQ8@1224|Proteobacteria,42M39@68525|delta/epsilon subdivisions,2WJEZ@28221|Deltaproteobacteria,2YTW3@29|Myxococcales	28221|Deltaproteobacteria	F	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SHD3_k127_2444010_1	1192034.CAP_7109	5.404e-137	458.0	2EGHW@1|root,33A9Z@2|Bacteria,1PM4Y@1224|Proteobacteria,43304@68525|delta/epsilon subdivisions,2WYJA@28221|Deltaproteobacteria,2Z1SV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2444010_0	448385.sce3600	8.52e-144	471.0	COG0463@1|root,COG2227@1|root,COG0463@2|Bacteria,COG2227@2|Bacteria,1NBIU@1224|Proteobacteria	1224|Proteobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Methyltransf_23
SHD3_k127_2444010_3	153721.MYP_465	7.492e-54	209.0	COG4775@1|root,COG4775@2|Bacteria,4NICB@976|Bacteroidetes,47PNV@768503|Cytophagia	976|Bacteroidetes	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
SHD3_k127_2444010_4	448385.sce3600	9.488e-28	124.0	COG0463@1|root,COG2227@1|root,COG0463@2|Bacteria,COG2227@2|Bacteria,1NBIU@1224|Proteobacteria	1224|Proteobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2,Methyltransf_23
SHD3_k127_244723_2	1379281.AVAG01000011_gene1275	6.447e-87	301.0	COG2059@1|root,COG2059@2|Bacteria,1MUBW@1224|Proteobacteria,42P92@68525|delta/epsilon subdivisions,2WKXT@28221|Deltaproteobacteria,2MA2T@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
SHD3_k127_244723_6	1242864.D187_002482	7.06e-40	164.0	COG0500@1|root,COG2226@2|Bacteria,1RC36@1224|Proteobacteria,42UDA@68525|delta/epsilon subdivisions,2WQHW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
SHD3_k127_244723_4	1278073.MYSTI_07172	3.084e-43	176.0	2BQUC@1|root,32JR4@2|Bacteria,1Q2FI@1224|Proteobacteria,4381F@68525|delta/epsilon subdivisions,2X3BH@28221|Deltaproteobacteria,2YV9D@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_244723_7	1254432.SCE1572_13870	2.04e-33	139.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_244723_5	378806.STAUR_3015	1.928e-41	172.0	2BQUC@1|root,32JR4@2|Bacteria,1Q2FI@1224|Proteobacteria,4381F@68525|delta/epsilon subdivisions,2X3BH@28221|Deltaproteobacteria,2YV9D@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_244723_0	290397.Adeh_0444	1.851e-119	395.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42N9C@68525|delta/epsilon subdivisions,2WJ2J@28221|Deltaproteobacteria,2YXSZ@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
SHD3_k127_244723_13	665577.JH993790_gene4825	8.847e-09	63.0	COG1846@1|root,COG1846@2|Bacteria,2IG43@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SHD3_k127_244723_9	82654.Pse7367_1722	4.439e-28	121.0	COG1309@1|root,COG1309@2|Bacteria,1GDI1@1117|Cyanobacteria	1117|Cyanobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_244723_3	204669.Acid345_0016	9.819e-76	272.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SHD3_k127_244723_1	448385.sce1797	2.947e-109	370.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,433ZY@68525|delta/epsilon subdivisions,2X4BJ@28221|Deltaproteobacteria,2Z0YV@29|Myxococcales	28221|Deltaproteobacteria	M	Spore coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
SHD3_k127_244723_8	290397.Adeh_0027	3.722e-28	116.0	COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,437IW@68525|delta/epsilon subdivisions,2X2SP@28221|Deltaproteobacteria,2YUPD@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SHD3_k127_2458235_18	886293.Sinac_6506	1.622e-05	51.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	lspG	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SHD3_k127_2458235_2	502025.Hoch_4153	1.288e-139	461.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YUJ9@29|Myxococcales	28221|Deltaproteobacteria	T	Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains	pilR	-	-	ko:K02667	ko02020,map02020	M00501	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_2458235_5	448385.sce2413	1.753e-101	349.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SHD3_k127_2458235_9	1192034.CAP_7527	2.079e-65	231.0	COG1595@1|root,COG1595@2|Bacteria,1QAB8@1224|Proteobacteria,434YB@68525|delta/epsilon subdivisions,2WZ98@28221|Deltaproteobacteria,2Z1MI@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_2458235_15	1192034.CAP_7525	9.036e-19	98.0	2A4WF@1|root,30TI4@2|Bacteria,1PDD5@1224|Proteobacteria,435F2@68525|delta/epsilon subdivisions,2WZSM@28221|Deltaproteobacteria,2Z2NW@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2458235_13	483219.LILAB_03340	1.267e-24	116.0	COG1560@1|root,COG1560@2|Bacteria,1MVNI@1224|Proteobacteria,42N6U@68525|delta/epsilon subdivisions,2WQ3X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Lipid A biosynthesis acyltransferase	htrB	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SHD3_k127_2458235_10	448385.sce2419	2.943e-63	237.0	COG0484@1|root,COG0484@2|Bacteria,1R0C7@1224|Proteobacteria,43CUM@68525|delta/epsilon subdivisions,2X82A@28221|Deltaproteobacteria,2Z3JM@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SHD3_k127_2458235_0	1254432.SCE1572_14590	7.707e-301	931.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YTUT@29|Myxococcales	28221|Deltaproteobacteria	O	heat shock protein 70	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SHD3_k127_2458235_12	448385.sce2421	7.562e-25	121.0	2DHU7@1|root,300Z2@2|Bacteria,1Q940@1224|Proteobacteria,433U6@68525|delta/epsilon subdivisions,2X3GR@28221|Deltaproteobacteria,2YW0V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TPR_14
SHD3_k127_2458235_1	448385.sce2422	3.909e-160	532.0	COG0308@1|root,COG0308@2|Bacteria,1P5AT@1224|Proteobacteria,433TV@68525|delta/epsilon subdivisions,2X3FG@28221|Deltaproteobacteria,2YVV0@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
SHD3_k127_2458235_17	631362.Thi970DRAFT_02111	4.347e-09	66.0	COG0642@1|root,COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,1RWY8@1236|Gammaproteobacteria,1X0FF@135613|Chromatiales	135613|Chromatiales	T	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SHD3_k127_2458235_8	1254432.SCE1572_10955	2.332e-68	238.0	COG1502@1|root,COG1502@2|Bacteria,1NZKD@1224|Proteobacteria,430D2@68525|delta/epsilon subdivisions,2WVTD@28221|Deltaproteobacteria,2YV79@29|Myxococcales	28221|Deltaproteobacteria	I	PLD-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_2
SHD3_k127_2458235_3	448385.sce3161	6.357e-113	381.0	COG0297@1|root,COG0297@2|Bacteria,1MUGM@1224|Proteobacteria,42MT8@68525|delta/epsilon subdivisions,2WITI@28221|Deltaproteobacteria,2YU1G@29|Myxococcales	28221|Deltaproteobacteria	F	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SHD3_k127_2458235_6	338966.Ppro_3174	1.188e-98	331.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,42N8G@68525|delta/epsilon subdivisions,2WKBC@28221|Deltaproteobacteria,43UK0@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
SHD3_k127_2458235_4	1192034.CAP_8954	4.802e-103	348.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42MDF@68525|delta/epsilon subdivisions,2X6EH@28221|Deltaproteobacteria,2Z3AS@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
SHD3_k127_2458235_7	1192034.CAP_8958	1.532e-75	259.0	COG0138@1|root,COG0138@2|Bacteria,1MUDQ@1224|Proteobacteria,42MV4@68525|delta/epsilon subdivisions,2WKHZ@28221|Deltaproteobacteria,2YTYA@29|Myxococcales	28221|Deltaproteobacteria	F	Bifunctional purine biosynthesis protein PurH	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
SHD3_k127_2460280_1	404589.Anae109_2802	5.351e-97	340.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_2460280_3	215803.DB30_2773	6.391e-09	69.0	COG1361@1|root,COG3055@1|root,COG1361@2|Bacteria,COG3055@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2460280_4	665956.HMPREF1032_02045	4.693e-05	57.0	COG0500@1|root,COG2226@2|Bacteria,1V0UT@1239|Firmicutes,24B8S@186801|Clostridia,3WINF@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Methyltransf_11,Methyltransf_25
SHD3_k127_2460280_0	248742.XP_005648862.1	4.552e-114	408.0	COG0574@1|root,2QS3J@2759|Eukaryota,37PTN@33090|Viridiplantae,34HF5@3041|Chlorophyta	3041|Chlorophyta	E	phosphoglucan water dikinase	PWD1	-	2.7.9.5	ko:K15535	-	-	-	-	ko00000,ko01000	-	-	-	CBM_20,PPDK_N
SHD3_k127_2460280_2	215803.DB30_0693	1.129e-66	244.0	COG2885@1|root,COG2885@2|Bacteria,1R7WJ@1224|Proteobacteria,42QJK@68525|delta/epsilon subdivisions,2WJX0@28221|Deltaproteobacteria,2YWI7@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA,TSP_3
SHD3_k127_2464794_6	1379270.AUXF01000002_gene1393	4.18e-06	49.0	2DRPS@1|root,33CHR@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SHD3_k127_2464794_3	448385.sce2076	1.426e-56	207.0	2A42Z@1|root,30SMX@2|Bacteria,1PBWJ@1224|Proteobacteria,4385D@68525|delta/epsilon subdivisions,2X3FD@28221|Deltaproteobacteria,2YVUP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2464794_2	1192034.CAP_8841	4.647e-86	293.0	COG1451@1|root,COG1451@2|Bacteria,1P1X1@1224|Proteobacteria,4314C@68525|delta/epsilon subdivisions,2X3BB@28221|Deltaproteobacteria,2YV83@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2464794_0	1192034.CAP_8843	3.481e-169	539.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YTSX@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SHD3_k127_2464794_4	485915.Dret_0980	1.019e-54	208.0	COG1253@1|root,COG1253@2|Bacteria,1MWT3@1224|Proteobacteria,42N45@68525|delta/epsilon subdivisions,2WKUD@28221|Deltaproteobacteria,2M8FS@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
SHD3_k127_2467885_4	665571.STHERM_c19770	2.368e-17	96.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2467885_3	1233950.IW22_09680	1.01e-17	97.0	COG4676@1|root,COG4676@2|Bacteria,4PGDK@976|Bacteroidetes,1IHDG@117743|Flavobacteriia,3ZU09@59732|Chryseobacterium	976|Bacteroidetes	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2467885_0	448385.sce1077	8.256e-49	185.0	COG3206@1|root,COG3206@2|Bacteria,1QZTF@1224|Proteobacteria,43CNF@68525|delta/epsilon subdivisions,2X7VS@28221|Deltaproteobacteria,2Z3IM@29|Myxococcales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF4349)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4349
SHD3_k127_2467885_2	1254432.SCE1572_26115	6.823e-35	141.0	COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,42VH9@68525|delta/epsilon subdivisions,2WT3R@28221|Deltaproteobacteria,2YVNR@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
SHD3_k127_2472954_4	316056.RPC_1161	4.11e-22	110.0	COG2271@1|root,COG2271@2|Bacteria,1MVPS@1224|Proteobacteria,2TTHW@28211|Alphaproteobacteria,3JT33@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	PFAM Major Facilitator Superfamily	gudP	-	-	ko:K03535	-	-	-	-	ko00000,ko02000	2.A.1.14.1	-	-	MFS_1
SHD3_k127_2472954_2	1192034.CAP_3350	4.021e-39	165.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42UMR@68525|delta/epsilon subdivisions,2WQ71@28221|Deltaproteobacteria,2YVN1@29|Myxococcales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SHD3_k127_2472954_6	9365.XP_007534993.1	0.0001464	55.0	COG0666@1|root,2QPYN@2759|Eukaryota,39W9Z@33154|Opisthokonta,3B98T@33208|Metazoa,3CZVJ@33213|Bilateria,482NW@7711|Chordata,48VQC@7742|Vertebrata,3J609@40674|Mammalia	33208|Metazoa	S	uveal autoantigen with coiled-coil domains and ankyrin repeats	UACA	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005829,GO:0006915,GO:0006950,GO:0006974,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008219,GO:0008630,GO:0008631,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010604,GO:0010646,GO:0010648,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0012501,GO:0012505,GO:0016020,GO:0019222,GO:0023051,GO:0023052,GO:0023057,GO:0030162,GO:0031323,GO:0031325,GO:0031347,GO:0031348,GO:0031967,GO:0031975,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032386,GO:0032388,GO:0032879,GO:0032880,GO:0032991,GO:0033157,GO:0033554,GO:0034599,GO:0035556,GO:0036473,GO:0042221,GO:0042306,GO:0042307,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043280,GO:0043281,GO:0043293,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045862,GO:0046822,GO:0046824,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0050727,GO:0050728,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051171,GO:0051173,GO:0051222,GO:0051223,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051716,GO:0052547,GO:0052548,GO:0060255,GO:0060341,GO:0065007,GO:0065009,GO:0070201,GO:0070887,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097190,GO:0097193,GO:1900180,GO:1900182,GO:1901222,GO:1901223,GO:1902531,GO:1902532,GO:1903827,GO:1903829,GO:1904589,GO:1904591,GO:1904951,GO:2000116,GO:2001056	-	-	-	-	-	-	-	-	-	-	Ank,Ank_2,Ank_4,Ank_5
SHD3_k127_2472954_3	357808.RoseRS_0746	9.04e-29	119.0	COG2018@1|root,COG2018@2|Bacteria,2G8WW@200795|Chloroflexi,375M5@32061|Chloroflexia	32061|Chloroflexia	S	PFAM Roadblock LC7 family protein	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
SHD3_k127_2472954_5	404380.Gbem_3883	3.524e-12	75.0	COG4656@1|root,COG4656@2|Bacteria,1R010@1224|Proteobacteria,42WXH@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SHD3_k127_2472954_0	398767.Glov_1553	2.654e-117	398.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,42N63@68525|delta/epsilon subdivisions,2WJPA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nickel-dependent hydrogenase, large subunit	mvhL	-	1.12.1.2,1.8.98.5	ko:K00436,ko:K14126	ko00680,map00680	-	R00019,R00700,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
SHD3_k127_2472954_1	398767.Glov_1552	1.344e-96	322.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42PVF@68525|delta/epsilon subdivisions,2WK6U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	mvhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
SHD3_k127_2475313_7	345341.KUTG_00701	9.787e-84	292.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria,4E1D9@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	AbfB,ArabFuran-catal,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_2475313_12	391625.PPSIR1_38004	4.471e-23	105.0	COG2963@1|root,COG2963@2|Bacteria,1N1MP@1224|Proteobacteria,43BIX@68525|delta/epsilon subdivisions,2X6XD@28221|Deltaproteobacteria,2YVUT@29|Myxococcales	28221|Deltaproteobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
SHD3_k127_2475313_8	1254432.SCE1572_00620	2.26e-75	263.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_2475313_9	1254432.SCE1572_00620	1.453e-73	259.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_2475313_5	448385.sce4100	9.015e-102	343.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria	1224|Proteobacteria	Q	Poly3-Hydroxybutyrate Depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase,Esterase_phd
SHD3_k127_2475313_0	448385.sce7481	5.719e-166	530.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2YV47@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SHD3_k127_2475313_6	448385.sce4591	4.834e-85	294.0	COG3693@1|root,COG3693@2|Bacteria,1R7BZ@1224|Proteobacteria	1224|Proteobacteria	G	Beta-xylanase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,CBM_10,CBM_2,CBM_4_9,CBM_5_12_2,CBM_6,Glyco_hydro_10,Glyco_hydro_43,SASA
SHD3_k127_2475313_3	391625.PPSIR1_18642	2.428e-116	389.0	COG2730@1|root,COG2730@2|Bacteria,1N21U@1224|Proteobacteria,435AG@68525|delta/epsilon subdivisions,2WZMJ@28221|Deltaproteobacteria,2Z2DK@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_2475313_11	1282362.AEAC466_07750	4.972e-49	179.0	COG0726@1|root,COG0726@2|Bacteria,1NVAH@1224|Proteobacteria	1224|Proteobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SHD3_k127_2475313_10	595460.RRSWK_00524	5.556e-52	199.0	COG1609@1|root,COG4977@1|root,COG1609@2|Bacteria,COG4977@2|Bacteria,2IXTX@203682|Planctomycetes	203682|Planctomycetes	K	Xylose operon regulatory protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
SHD3_k127_2475313_2	448385.sce8082	2.226e-117	391.0	COG2730@1|root,COG2730@2|Bacteria,1PSHN@1224|Proteobacteria,434Y6@68525|delta/epsilon subdivisions,2WZ90@28221|Deltaproteobacteria,2Z1M0@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Cellulase
SHD3_k127_2475313_4	509190.Cseg_1900	2.615e-110	371.0	COG0657@1|root,COG0657@2|Bacteria,1QDQP@1224|Proteobacteria,2U41U@28211|Alphaproteobacteria,2KI9H@204458|Caulobacterales	204458|Caulobacterales	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
SHD3_k127_247717_4	1121373.KB903644_gene3398	5.102e-120	395.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
SHD3_k127_247717_6	377629.TERTU_2314	1.099e-69	251.0	COG4677@1|root,COG4677@2|Bacteria,1RCVZ@1224|Proteobacteria,1S3H0@1236|Gammaproteobacteria,2PPJ6@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	CBM_6,Pectinesterase
SHD3_k127_247717_5	44060.JODL01000004_gene2418	1.417e-80	282.0	COG3693@1|root,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_2,Glyco_hydro_10
SHD3_k127_247717_10	285535.JOEY01000070_gene524	8.285e-32	130.0	COG3693@1|root,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_10,Glyco_hydro_62
SHD3_k127_247717_11	710111.FraQA3DRAFT_0983	2.968e-07	53.0	COG4977@1|root,COG4977@2|Bacteria,2ICMN@201174|Actinobacteria,4EWX9@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07506	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
SHD3_k127_247717_9	521674.Plim_0774	5.207e-35	148.0	COG1609@1|root,COG2207@1|root,COG1609@2|Bacteria,COG2207@2|Bacteria,2IXTX@203682|Planctomycetes	203682|Planctomycetes	K	Xylose operon regulatory protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,HTH_AraC,Peripla_BP_3
SHD3_k127_247717_2	1210884.HG799473_gene14952	5.735e-139	462.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2IY3H@203682|Planctomycetes	203682|Planctomycetes	P	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
SHD3_k127_247717_3	1123487.KB892840_gene53	5.68e-122	404.0	COG3866@1|root,COG3866@2|Bacteria,1QPFF@1224|Proteobacteria,2VYRZ@28216|Betaproteobacteria	28216|Betaproteobacteria	G	Pectate lyase	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase_C
SHD3_k127_247717_1	452637.Oter_3558	3.277e-216	688.0	COG1032@1|root,COG1032@2|Bacteria,46V7P@74201|Verrucomicrobia,3K74V@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SHD3_k127_247717_7	502025.Hoch_6359	2.029e-40	167.0	2AF1T@1|root,31507@2|Bacteria,1PUYN@1224|Proteobacteria,43842@68525|delta/epsilon subdivisions,2X3E0@28221|Deltaproteobacteria,2YVMX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_247717_0	1125863.JAFN01000001_gene1462	2.165e-311	973.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SHD3_k127_2477545_1	404589.Anae109_2939	4.235e-123	407.0	COG1032@1|root,COG1032@2|Bacteria,1MY2Y@1224|Proteobacteria,42NG3@68525|delta/epsilon subdivisions,2WJ95@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SHD3_k127_2477545_4	1144275.COCOR_01774	8.153e-72	259.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	2.4.1.80	ko:K00720	ko00600,ko01100,map00600,map01100	M00066	R01497	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko02000	4.D.1.4	GT21	-	Glyco_transf_21
SHD3_k127_2477545_6	497964.CfE428DRAFT_1503	2.394e-12	76.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2,START
SHD3_k127_2477545_2	448385.sce0876	7.696e-115	393.0	COG1716@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315,ko:K16922	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01002,ko03021	-	-	-	CHASE2,FHA,GAF_2,HATPase_c_2,SpoIIE,Yop-YscD_cpl
SHD3_k127_2477545_0	3055.EDP07087	7.04e-187	626.0	COG0574@1|root,2QQ6R@2759|Eukaryota,37KSG@33090|Viridiplantae,34GN6@3041|Chlorophyta	3041|Chlorophyta	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	GWD1	-	2.7.9.4	ko:K08244	-	-	-	-	ko00000,ko01000	-	-	-	PPDK_N
SHD3_k127_2477545_5	1192034.CAP_0553	1.477e-24	113.0	2AH09@1|root,31793@2|Bacteria,1PYJ1@1224|Proteobacteria,435DZ@68525|delta/epsilon subdivisions,2WZRH@28221|Deltaproteobacteria,2Z2KK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2477545_7	1242864.D187_003348	2.525e-06	49.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C,HYR,Laminin_G_3,Phosphodiest
SHD3_k127_2489760_0	269799.Gmet_3417	2.487e-51	207.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,43T5D@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SHD3_k127_2489760_5	443143.GM18_3605	7.097e-08	66.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	CheX,HATPase_c,HisKA,Response_reg
SHD3_k127_2489760_1	448385.sce0007	9.251e-51	188.0	COG0735@1|root,COG0735@2|Bacteria,1RDWJ@1224|Proteobacteria,42MN8@68525|delta/epsilon subdivisions,2WQKR@28221|Deltaproteobacteria,2YVE5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the Fur family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SHD3_k127_2489760_4	290397.Adeh_0249	5.881e-09	69.0	COG1413@1|root,COG1413@2|Bacteria,1QX4H@1224|Proteobacteria,42Z02@68525|delta/epsilon subdivisions,2WUJ9@28221|Deltaproteobacteria,2YVP1@29|Myxococcales	28221|Deltaproteobacteria	C	Type II secretion system (T2SS), protein E, N-terminal domain	frgA	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,T2SSE_N
SHD3_k127_2489760_7	1042156.CXIVA_10510	0.0004237	48.0	2C0W2@1|root,306ZY@2|Bacteria,1V5YY@1239|Firmicutes,24I0Q@186801|Clostridia,36KJD@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_7,MqsA_antitoxin
SHD3_k127_2489760_2	596154.Alide2_3689	2.38e-48	175.0	COG3169@1|root,COG3169@2|Bacteria,1RHBQ@1224|Proteobacteria,2VSWS@28216|Betaproteobacteria,4AE2H@80864|Comamonadaceae	28216|Betaproteobacteria	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
SHD3_k127_2489760_6	861299.J421_5914	2.012e-07	62.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,Metallophos,NACHT,Trypsin_2
SHD3_k127_2490873_2	383372.Rcas_0264	8.844e-112	372.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2490873_0	1227739.Hsw_2707	1.02e-137	448.0	COG1085@1|root,COG1085@2|Bacteria,4NEY9@976|Bacteroidetes,47MHS@768503|Cytophagia	976|Bacteroidetes	G	Galactose-1-phosphate uridyl transferase, C-terminal domain	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
SHD3_k127_2490873_1	1185876.BN8_04811	3.939e-121	401.0	COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,47JY8@768503|Cytophagia	976|Bacteroidetes	G	Belongs to the GHMP kinase family. GalK subfamily	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
SHD3_k127_251337_4	1123320.KB889675_gene4116	7.03e-06	58.0	COG0699@1|root,COG0699@2|Bacteria,2GU1B@201174|Actinobacteria	201174|Actinobacteria	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SHD3_k127_251337_0	1162668.LFE_1389	7.552e-126	419.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_251337_3	1206777.B195_18654	6.221e-18	96.0	2AD2S@1|root,312R0@2|Bacteria,1RDQX@1224|Proteobacteria,1S3Y6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_251337_5	446462.Amir_0743	0.0002322	53.0	COG1051@1|root,COG1051@2|Bacteria,2I2P7@201174|Actinobacteria,4E2A1@85010|Pseudonocardiales	201174|Actinobacteria	F	Glycosyltransferase family 87	pimE	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13669	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87,NUDIX
SHD3_k127_251337_1	502025.Hoch_6847	4.491e-58	218.0	2A7CW@1|root,30W9W@2|Bacteria,1QAR7@1224|Proteobacteria,43591@68525|delta/epsilon subdivisions,2WZK7@28221|Deltaproteobacteria,2Z2AT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_251337_2	448385.sce3943	1.219e-40	159.0	COG3628@1|root,COG3628@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2521058_12	7176.CPIJ020109-PA	2.956e-06	60.0	COG5640@1|root,KOG3627@2759|Eukaryota,3A0PZ@33154|Opisthokonta,3BQ4K@33208|Metazoa,3D72Z@33213|Bilateria,41YRY@6656|Arthropoda,3SM5D@50557|Insecta,455U0@7147|Diptera,45K8S@7148|Nematocera	33208|Metazoa	O	Belongs to the peptidase S1 family	-	GO:0002225,GO:0002376,GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002700,GO:0002702,GO:0002759,GO:0002760,GO:0002784,GO:0002788,GO:0002804,GO:0002831,GO:0002833,GO:0002920,GO:0002922,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008592,GO:0009605,GO:0009607,GO:0009617,GO:0009620,GO:0009966,GO:0009967,GO:0010646,GO:0010647,GO:0016787,GO:0017171,GO:0019538,GO:0023051,GO:0023056,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0042742,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043900,GO:0043902,GO:0044238,GO:0045087,GO:0045752,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050830,GO:0050832,GO:0050896,GO:0051704,GO:0051707,GO:0065007,GO:0070011,GO:0071704,GO:0080134,GO:0098542,GO:0140096,GO:1900150,GO:1901564	-	ko:K20673	ko04624,map04624	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLIP,Trypsin
SHD3_k127_2521058_4	99598.Cal7507_0669	7.624e-41	158.0	COG1853@1|root,COG1853@2|Bacteria,1G841@1117|Cyanobacteria	1117|Cyanobacteria	S	Conserved protein of dim6 ntab family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SHD3_k127_2521058_14	584708.Apau_0714	0.0002768	48.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	DUF3795,OsmC
SHD3_k127_2521058_8	1254432.SCE1572_37545	9.362e-20	105.0	COG2518@1|root,COG2518@2|Bacteria	2|Bacteria	O	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SHD3_k127_2521058_11	237368.SCABRO_01644	9.722e-17	95.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	B12-binding,Glycos_transf_2,Radical_SAM
SHD3_k127_2521058_9	573061.Clocel_0940	4.499e-18	96.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,NUDIX,PqqD,Radical_SAM,SPASM
SHD3_k127_2521058_1	313612.L8106_23745	1.906e-67	244.0	COG2227@1|root,COG2227@2|Bacteria,1G0ZD@1117|Cyanobacteria,1H8ZA@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_2521058_3	40571.JOEA01000004_gene6317	4.443e-51	206.0	COG4249@1|root,COG4249@2|Bacteria,2IAM3@201174|Actinobacteria,4E3RZ@85010|Pseudonocardiales	201174|Actinobacteria	O	Caspase domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
SHD3_k127_2521058_10	448385.sce2918	2.303e-17	86.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
SHD3_k127_2521058_0	404589.Anae109_3247	6.506e-113	383.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C
SHD3_k127_2521058_2	502025.Hoch_2253	1.642e-65	244.0	COG2931@1|root,COG2931@2|Bacteria,1PG5F@1224|Proteobacteria,43F2Q@68525|delta/epsilon subdivisions,2X35A@28221|Deltaproteobacteria,2YY8H@29|Myxococcales	28221|Deltaproteobacteria	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2521058_6	1120950.KB892790_gene2060	4.306e-27	126.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4DNR0@85009|Propionibacteriales	201174|Actinobacteria	K	Periplasmic binding protein-like domain	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	LacI,Peripla_BP_3
SHD3_k127_2523011_2	1283283.ATXA01000015_gene107	9.218e-78	275.0	2DB7V@1|root,2Z7NX@2|Bacteria,2I9CJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2523011_3	1122915.AUGY01000137_gene3425	1.164e-76	269.0	COG0760@1|root,COG0760@2|Bacteria,1VN0T@1239|Firmicutes,4HRP5@91061|Bacilli,277QB@186822|Paenibacillaceae	91061|Bacilli	O	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
SHD3_k127_2523011_0	1192034.CAP_4581	1.129e-127	437.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SHD3_k127_2523011_6	448385.sce4315	6.23e-36	144.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2X5KN@28221|Deltaproteobacteria,2YXI5@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SHD3_k127_2523011_7	404589.Anae109_0872	4.786e-34	135.0	COG0848@1|root,COG0848@2|Bacteria,1NE2Q@1224|Proteobacteria,42VAE@68525|delta/epsilon subdivisions,2WRCE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SHD3_k127_2523011_11	404589.Anae109_0871	1.159e-12	79.0	COG0810@1|root,COG0810@2|Bacteria,1NFMG@1224|Proteobacteria,42UAW@68525|delta/epsilon subdivisions,2WTBZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_C
SHD3_k127_2523011_9	246197.MXAN_0455	4.089e-23	115.0	COG4249@1|root,COG4249@2|Bacteria,1QX7K@1224|Proteobacteria,43AHW@68525|delta/epsilon subdivisions,2X5Y0@28221|Deltaproteobacteria,2Z147@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2523011_4	1192034.CAP_0295	2.561e-60	216.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
SHD3_k127_2523011_5	1453505.JASY01000008_gene800	6.967e-45	186.0	COG3534@1|root,COG3534@2|Bacteria,4NJ6F@976|Bacteroidetes,1IDJU@117743|Flavobacteriia,2NYMS@237|Flavobacterium	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2523011_10	448385.sce9011	1.961e-16	89.0	COG1716@1|root,COG1716@2|Bacteria,1PFN8@1224|Proteobacteria,435DQ@68525|delta/epsilon subdivisions,2WZR8@28221|Deltaproteobacteria,2Z2JZ@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SHD3_k127_2523011_1	448385.sce3942	8.216e-84	300.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_2523011_13	1121286.AUMT01000005_gene3091	0.0003227	52.0	COG3866@1|root,COG5563@1|root,COG3866@2|Bacteria,COG5563@2|Bacteria,4NRK6@976|Bacteroidetes,1IIHW@117743|Flavobacteriia,3ZQ5Q@59732|Chryseobacterium	976|Bacteroidetes	G	endonuclease I	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2557457_3	1163409.UUA_02656	6.92e-28	123.0	COG3664@1|root,COG3664@2|Bacteria,1MWYX@1224|Proteobacteria,1T828@1236|Gammaproteobacteria,1XA2A@135614|Xanthomonadales	135614|Xanthomonadales	G	Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
SHD3_k127_2557457_8	264462.Bd2136	0.0001873	51.0	COG2900@1|root,COG2900@2|Bacteria,1PTYV@1224|Proteobacteria,437SC@68525|delta/epsilon subdivisions,2MUIE@213481|Bdellovibrionales,2X31D@28221|Deltaproteobacteria	213481|Bdellovibrionales	S	SlyX	-	-	-	ko:K03745	-	-	-	-	ko00000	-	-	-	SlyX
SHD3_k127_2557457_2	246197.MXAN_2579	6.945e-51	198.0	COG1409@1|root,COG3291@1|root,COG1409@2|Bacteria,COG3291@2|Bacteria,1N85S@1224|Proteobacteria,42WZ6@68525|delta/epsilon subdivisions,2WT5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_C,PKD,Pur_ac_phosph_N
SHD3_k127_2557457_1	1242864.D187_007221	4.303e-81	297.0	COG0515@1|root,COG0515@2|Bacteria	1242864.D187_007221|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2557457_0	448385.sce5204	9.881e-86	317.0	COG1609@1|root,COG2208@1|root,COG1609@2|Bacteria,COG2208@2|Bacteria,1RHRV@1224|Proteobacteria,43ARR@68525|delta/epsilon subdivisions,2X65U@28221|Deltaproteobacteria,2Z0U1@29|Myxococcales	28221|Deltaproteobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3,SpoIIE
SHD3_k127_2557457_6	1382359.JIAL01000001_gene1333	1.045e-20	98.0	2EHGM@1|root,33B8H@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3147
SHD3_k127_2557457_7	1040989.AWZU01000011_gene4044	3.933e-19	94.0	2EM11@1|root,33EQJ@2|Bacteria,1RGA8@1224|Proteobacteria,2U6Z8@28211|Alphaproteobacteria,3JYWR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3147)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3147
SHD3_k127_2557457_4	871963.Desdi_1785	2.512e-25	111.0	COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,24P0N@186801|Clostridia,2670K@186807|Peptococcaceae	186801|Clostridia	S	CoA-binding protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
SHD3_k127_256013_0	509191.AEDB02000002_gene1143	0.0	1422.0	COG4193@1|root,COG5297@1|root,COG5520@1|root,COG4193@2|Bacteria,COG5297@2|Bacteria,COG5520@2|Bacteria,1UY9C@1239|Firmicutes,24AA0@186801|Clostridia,3WH86@541000|Ruminococcaceae	186801|Clostridia	GM	Glycosyl hydrolase family 59	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,Glyco_hydro_59
SHD3_k127_256013_4	639030.JHVA01000001_gene3757	0.0004344	53.0	COG1749@1|root,COG2372@1|root,COG4257@1|root,COG4932@1|root,COG1749@2|Bacteria,COG2372@2|Bacteria,COG4257@2|Bacteria,COG4932@2|Bacteria,3Y930@57723|Acidobacteria	57723|Acidobacteria	M	Flagellar hook protein flgE	-	-	-	-	-	-	-	-	-	-	-	-	DUF4082
SHD3_k127_256013_2	1869.MB27_01580	5.234e-57	213.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4DI53@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 12 (cellulase H) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12
SHD3_k127_256013_3	326427.Cagg_0670	1.469e-41	168.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_256013_1	1120949.KB903294_gene4355	4.065e-84	294.0	COG2755@1|root,COG5297@1|root,COG2755@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria,4DCHA@85008|Micromonosporales	201174|Actinobacteria	EG	Alpha-L-arabinofuranosidase B, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_2564734_0	448385.sce0417	5.07e-180	583.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,42M4Z@68525|delta/epsilon subdivisions,2WJ0D@28221|Deltaproteobacteria,2YUHW@29|Myxococcales	28221|Deltaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
SHD3_k127_2564734_1	1156937.MFUM_40010	1.364e-118	394.0	COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia,37H6N@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_2564734_4	313606.M23134_01153	1.48e-13	73.0	2EMN4@1|root,33FAG@2|Bacteria,4NYZA@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2564734_2	448385.sce5273	1.55e-34	141.0	COG5622@1|root,COG5622@2|Bacteria,1N6XP@1224|Proteobacteria,42WPJ@68525|delta/epsilon subdivisions,2WR9D@28221|Deltaproteobacteria,2YW59@29|Myxococcales	28221|Deltaproteobacteria	N	Protein required for attachment to host cells	-	-	-	-	-	-	-	-	-	-	-	-	Host_attach
SHD3_k127_2564734_3	448385.sce4856	1.687e-28	121.0	COG3558@1|root,COG3558@2|Bacteria,1RA64@1224|Proteobacteria,43067@68525|delta/epsilon subdivisions,2WVBM@28221|Deltaproteobacteria,2YV2I@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1348)	-	-	-	ko:K09958	-	-	-	-	ko00000	-	-	-	DUF1348
SHD3_k127_2578800_5	1254432.SCE1572_25630	1.312e-17	88.0	2EGD2@1|root,33A4V@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
SHD3_k127_2578800_0	1254432.SCE1572_26060	4.872e-85	294.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2X5KN@28221|Deltaproteobacteria,2YXI5@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SHD3_k127_2578800_4	1192034.CAP_6961	4.069e-43	163.0	COG0848@1|root,COG0848@2|Bacteria,1N9DN@1224|Proteobacteria,42V0H@68525|delta/epsilon subdivisions,2WQGB@28221|Deltaproteobacteria,2Z0IY@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SHD3_k127_2578800_2	1254432.SCE1572_26070	6.374e-50	189.0	29R0Y@1|root,30C22@2|Bacteria,1Q9H7@1224|Proteobacteria,434DR@68525|delta/epsilon subdivisions,2X8U5@28221|Deltaproteobacteria,2Z0E2@29|Myxococcales	28221|Deltaproteobacteria	S	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SHD3_k127_2578800_1	1254432.SCE1572_26075	2.017e-69	239.0	COG0664@1|root,COG0664@2|Bacteria,1NBX3@1224|Proteobacteria,42UGQ@68525|delta/epsilon subdivisions,2WQY8@28221|Deltaproteobacteria,2YVI9@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
SHD3_k127_2578800_3	1192034.CAP_0106	1.021e-46	171.0	COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42SP5@68525|delta/epsilon subdivisions,2WP39@28221|Deltaproteobacteria,2YUQU@29|Myxococcales	28221|Deltaproteobacteria	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
SHD3_k127_2583737_0	404589.Anae109_3091	4.472e-175	575.0	COG1033@1|root,COG1033@2|Bacteria,1MUE1@1224|Proteobacteria,42ME2@68525|delta/epsilon subdivisions,2WJRI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	PFAM MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SHD3_k127_2583737_2	391625.PPSIR1_16065	5.475e-20	92.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	CP_0018	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SHD3_k127_2587904_2	680198.SCAB_60111	2.902e-19	88.0	COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,2IBZD@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_4,Glycos_transf_2
SHD3_k127_2587904_1	1961.JOAK01000017_gene658	3.78e-79	272.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SHD3_k127_2587904_3	1278073.MYSTI_04398	2.255e-11	68.0	COG4305@1|root,COG4305@2|Bacteria,1MYW4@1224|Proteobacteria,434JK@68525|delta/epsilon subdivisions,2WYWV@28221|Deltaproteobacteria,2Z0TT@29|Myxococcales	28221|Deltaproteobacteria	G	Rare lipoprotein A (RlpA)-like double-psi beta-barrel	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	DPBB_1,Pollen_allerg_1
SHD3_k127_2587904_0	1254432.SCE1572_38245	2.108e-224	734.0	COG1948@1|root,COG5276@1|root,COG4880@2|Bacteria,COG5276@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SHD3_k127_2598769_7	448385.sce8154	2.582e-99	344.0	COG2199@1|root,COG4567@1|root,COG2199@2|Bacteria,COG4567@2|Bacteria,1R0DZ@1224|Proteobacteria,43CWF@68525|delta/epsilon subdivisions,2X84G@28221|Deltaproteobacteria,2Z3KS@29|Myxococcales	28221|Deltaproteobacteria	KT	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SHD3_k127_2598769_24	479434.Sthe_1691	7.19e-14	78.0	COG1872@1|root,COG1872@2|Bacteria,2G9SM@200795|Chloroflexi,27YQ3@189775|Thermomicrobia	189775|Thermomicrobia	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
SHD3_k127_2598769_25	235985.BBPN01000022_gene2534	6.607e-06	56.0	COG1309@1|root,COG1309@2|Bacteria,2IP2Y@201174|Actinobacteria,2NJ52@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_2598769_6	448385.sce8160	3.814e-102	347.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YUQI@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide	bioF	-	2.3.1.29,2.3.1.47	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	M00123,M00573,M00577	R00371,R03210,R10124	RC00004,RC00039,RC00394,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SHD3_k127_2598769_16	448385.sce8161	6.296e-35	150.0	COG0132@1|root,COG0132@2|Bacteria,1RDRK@1224|Proteobacteria,42SQE@68525|delta/epsilon subdivisions,2WNR7@28221|Deltaproteobacteria,2YW18@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
SHD3_k127_2598769_13	1254432.SCE1572_47475	2.316e-51	189.0	COG1131@1|root,COG1131@2|Bacteria,1RKFP@1224|Proteobacteria,42RXI@68525|delta/epsilon subdivisions,2WNB9@28221|Deltaproteobacteria,2Z263@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	ccmA	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
SHD3_k127_2598769_2	1254432.SCE1572_48300	1.531e-141	462.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WIYY@28221|Deltaproteobacteria,2YWP3@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SHD3_k127_2598769_3	448385.sce8272	7.475e-127	419.0	COG1721@1|root,COG1721@2|Bacteria,1N8IQ@1224|Proteobacteria,42S2K@68525|delta/epsilon subdivisions,2WNA2@28221|Deltaproteobacteria,2YVGE@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SHD3_k127_2598769_0	448385.sce8271	1.303e-229	735.0	COG1305@1|root,COG1305@2|Bacteria,1MWCE@1224|Proteobacteria,42NIZ@68525|delta/epsilon subdivisions,2WM5U@28221|Deltaproteobacteria,2Z315@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF3488)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3488,DUF4129,Transglut_core
SHD3_k127_2598769_9	1254432.SCE1572_47595	9.673e-77	275.0	COG2856@1|root,COG2856@2|Bacteria,1PADA@1224|Proteobacteria,434WD@68525|delta/epsilon subdivisions,2WZ7C@28221|Deltaproteobacteria,2Z1HG@29|Myxococcales	28221|Deltaproteobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2598769_8	1254432.SCE1572_47590	1.621e-82	282.0	COG0036@1|root,COG0036@2|Bacteria,1MUZM@1224|Proteobacteria,42NC0@68525|delta/epsilon subdivisions,2WJK9@28221|Deltaproteobacteria,2YURC@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
SHD3_k127_2598769_11	448385.sce8188	2.68e-61	217.0	COG0454@1|root,COG0456@2|Bacteria,1PYGZ@1224|Proteobacteria,435DK@68525|delta/epsilon subdivisions,2WZR5@28221|Deltaproteobacteria,2Z2JT@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SHD3_k127_2598769_12	1192034.CAP_5352	2.267e-56	209.0	COG0664@1|root,COG0664@2|Bacteria,1N61M@1224|Proteobacteria,42Y1U@68525|delta/epsilon subdivisions,2WNPK@28221|Deltaproteobacteria,2YVYQ@29|Myxococcales	28221|Deltaproteobacteria	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
SHD3_k127_2598769_14	1380390.JIAT01000010_gene4177	1.512e-41	163.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CQPM@84995|Rubrobacteria	84995|Rubrobacteria	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
SHD3_k127_2598769_26	401526.TcarDRAFT_0634	8.462e-06	57.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,4H25Z@909932|Negativicutes	909932|Negativicutes	E	3-deoxy-7-phosphoheptulonate synthase	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
SHD3_k127_2598769_10	502025.Hoch_0362	2.383e-74	270.0	COG0515@1|root,COG0515@2|Bacteria,1MWVZ@1224|Proteobacteria,4389R@68525|delta/epsilon subdivisions,2XA3N@28221|Deltaproteobacteria,2YWAI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
SHD3_k127_2598769_1	1254432.SCE1572_47375	3.898e-181	576.0	COG0172@1|root,COG0172@2|Bacteria,1MUJF@1224|Proteobacteria,42M7H@68525|delta/epsilon subdivisions,2WIT7@28221|Deltaproteobacteria,2YWV6@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_3528	Seryl_tRNA_N,tRNA-synt_2b
SHD3_k127_2598769_22	1385935.N836_25275	1.339e-26	119.0	COG1359@1|root,COG1359@2|Bacteria,1G8H0@1117|Cyanobacteria,1HC7H@1150|Oscillatoriales	1117|Cyanobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
SHD3_k127_2598769_4	1499967.BAYZ01000118_gene3300	8.619e-111	370.0	COG1454@1|root,COG1454@2|Bacteria,2NQ5W@2323|unclassified Bacteria	2|Bacteria	C	Iron-containing alcohol dehydrogenase	CT0951	-	1.1.1.1,4.3.3.7	ko:K00001,ko:K01714,ko:K13954	ko00010,ko00071,ko00261,ko00300,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,ko01230,map00010,map00071,map00261,map00300,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220,map01230	M00016,M00525,M00526,M00527	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310,R10147	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273,RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	Fe-ADH
SHD3_k127_2598769_20	1347087.CBYO010000022_gene3809	8.457e-28	118.0	COG0454@1|root,COG0456@2|Bacteria,1V3K1@1239|Firmicutes,4IUBH@91061|Bacilli	91061|Bacilli	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2598769_19	1278073.MYSTI_02529	2.765e-28	131.0	COG2982@1|root,COG2982@2|Bacteria,1NVUY@1224|Proteobacteria,42P4T@68525|delta/epsilon subdivisions,2WKBS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	AsmA family	-	-	-	ko:K07289	-	-	-	-	ko00000	-	-	-	AsmA,AsmA_2
SHD3_k127_2598769_18	459495.SPLC1_S011140	2.463e-29	128.0	COG1942@1|root,COG1942@2|Bacteria,1G6RE@1117|Cyanobacteria,1HBS7@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM macrophage migration inhibitory factor	-	-	-	-	-	-	-	-	-	-	-	-	MIF
SHD3_k127_2614131_3	378806.STAUR_0974	5.993e-11	64.0	COG2197@1|root,COG2197@2|Bacteria,1NQDZ@1224|Proteobacteria,438UN@68525|delta/epsilon subdivisions,2X9IP@28221|Deltaproteobacteria,2YXTR@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
SHD3_k127_2614131_2	309801.trd_1551	3.878e-18	89.0	COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi,27XKP@189775|Thermomicrobia	189775|Thermomicrobia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SHD3_k127_2614131_1	269799.Gmet_1606	6.94e-21	106.0	COG1406@1|root,COG1406@2|Bacteria,1N7TT@1224|Proteobacteria,433FF@68525|delta/epsilon subdivisions,2WXSM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Chemotaxis phosphatase CheX	cheX-4	-	-	-	-	-	-	-	-	-	-	-	CheX
SHD3_k127_2614131_0	204669.Acid345_3285	5.616e-185	594.0	COG0531@1|root,COG0531@2|Bacteria,3Y3QM@57723|Acidobacteria,2JIFD@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SHD3_k127_2618460_0	1385514.N782_17545	2.861e-68	246.0	arCOG06802@1|root,2ZBBG@2|Bacteria,1V17K@1239|Firmicutes,4HTUX@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2618460_1	1121422.AUMW01000002_gene2122	5.305e-52	206.0	COG2202@1|root,COG2203@1|root,COG3437@1|root,COG4191@1|root,COG5002@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1TQ0S@1239|Firmicutes,24800@186801|Clostridia,260QX@186807|Peptococcaceae	186801|Clostridia	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE4,GGDEF,HD,HD_5,PAS,PAS_4,PAS_9,dCache_1
SHD3_k127_2641593_2	643473.KB235931_gene5000	2.315e-102	339.0	COG0730@1|root,COG0730@2|Bacteria,1G3K1@1117|Cyanobacteria,1HRXH@1161|Nostocales	1117|Cyanobacteria	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SHD3_k127_2641593_6	1174528.JH992889_gene106	3.321e-28	121.0	COG4272@1|root,COG4272@2|Bacteria,1G9P7@1117|Cyanobacteria,1JIUX@1189|Stigonemataceae	1117|Cyanobacteria	S	Protein of unknown function (DUF1634)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1634
SHD3_k127_2641593_3	404589.Anae109_2358	4.956e-66	234.0	COG0500@1|root,COG2226@2|Bacteria,1MVXN@1224|Proteobacteria,43A75@68525|delta/epsilon subdivisions,2X9W3@28221|Deltaproteobacteria,2Z1PF@29|Myxococcales	28221|Deltaproteobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
SHD3_k127_2641593_5	404589.Anae109_2360	9.137e-38	144.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	-	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
SHD3_k127_2641593_1	404589.Anae109_2361	1.33e-126	412.0	COG0492@1|root,COG0492@2|Bacteria,1MV15@1224|Proteobacteria,42MHR@68525|delta/epsilon subdivisions,2WIY8@28221|Deltaproteobacteria,2YUI6@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
SHD3_k127_2641593_0	404589.Anae109_2359	8.573e-164	527.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
SHD3_k127_2641593_10	290397.Adeh_2146	1.346e-10	69.0	COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1RCP7@1224|Proteobacteria,42Q7J@68525|delta/epsilon subdivisions,2WJCK@28221|Deltaproteobacteria,2Z04N@29|Myxococcales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	ccdA	-	-	ko:K06196	-	-	-	-	ko00000,ko02000	5.A.1.2	-	-	DsbD,Thioredoxin
SHD3_k127_2641593_4	404589.Anae109_2204	9.081e-40	152.0	COG0526@1|root,COG0526@2|Bacteria,1QVCY@1224|Proteobacteria,43BX7@68525|delta/epsilon subdivisions,2X780@28221|Deltaproteobacteria,2Z3DU@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	trx	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SHD3_k127_2641593_9	573413.Spirs_3569	3.307e-15	83.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	bta	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin,TraF
SHD3_k127_2641593_7	926560.KE387027_gene360	3.689e-25	116.0	2DQW0@1|root,3390A@2|Bacteria,1WMJN@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2641593_8	502025.Hoch_2847	3.126e-21	99.0	COG2105@1|root,COG2105@2|Bacteria,1N94Q@1224|Proteobacteria,42X7M@68525|delta/epsilon subdivisions,2WSFG@28221|Deltaproteobacteria,2YVYK@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM AIG2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
SHD3_k127_2643348_6	1192034.CAP_2724	5.203e-85	285.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SHD3_k127_2643348_3	1254432.SCE1572_18050	2.266e-114	383.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,42NYP@68525|delta/epsilon subdivisions,2WIPJ@28221|Deltaproteobacteria,2YUUX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_2643348_8	1192034.CAP_8997	7.232e-66	248.0	COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,42MPK@68525|delta/epsilon subdivisions,2WJM1@28221|Deltaproteobacteria,2YVM8@29|Myxococcales	28221|Deltaproteobacteria	O	peptidylprolyl isomerase	nifM	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SHD3_k127_2643348_1	1192034.CAP_8993	1.063e-204	656.0	COG1199@1|root,COG1199@2|Bacteria,1MVCU@1224|Proteobacteria,42N57@68525|delta/epsilon subdivisions,2WJ82@28221|Deltaproteobacteria,2YUK7@29|Myxococcales	28221|Deltaproteobacteria	KL	SMART helicase c2	yoaA	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_2,Helicase_C_2,ResIII
SHD3_k127_2643348_9	1254432.SCE1572_13970	3.459e-58	212.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_2643348_0	1192034.CAP_5971	0.0	1052.0	COG2911@1|root,COG2982@1|root,COG2911@2|Bacteria,COG2982@2|Bacteria,1PQTA@1224|Proteobacteria,42PYT@68525|delta/epsilon subdivisions,2WIZ6@28221|Deltaproteobacteria,2YVF0@29|Myxococcales	28221|Deltaproteobacteria	M	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SHD3_k127_2643348_7	1192034.CAP_4934	5.077e-69	242.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2X2EG@28221|Deltaproteobacteria,2Z20T@29|Myxococcales	28221|Deltaproteobacteria	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SHD3_k127_2643348_2	483219.LILAB_08270	3.959e-120	409.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2YX39@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_8,PAS_9,Response_reg
SHD3_k127_2643348_4	502025.Hoch_6435	8.722e-103	349.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2X36T@28221|Deltaproteobacteria,2YUK1@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SHD3_k127_2643348_10	246197.MXAN_3206	7.818e-53	200.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SHD3_k127_2643348_11	448385.sce7258	6.322e-27	113.0	COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,42V07@68525|delta/epsilon subdivisions,2WRQ6@28221|Deltaproteobacteria,2YW65@29|Myxococcales	28221|Deltaproteobacteria	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
SHD3_k127_2643348_5	448385.sce7257	4.1e-85	289.0	COG0500@1|root,COG0500@2|Bacteria,1R0DM@1224|Proteobacteria,43CW7@68525|delta/epsilon subdivisions,2X847@28221|Deltaproteobacteria,2Z3KJ@29|Myxococcales	28221|Deltaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_2652351_0	330214.NIDE0726	3.203e-299	950.0	COG0841@1|root,COG0841@2|Bacteria,3J0ZG@40117|Nitrospirae	40117|Nitrospirae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SHD3_k127_2652351_4	1254432.SCE1572_21880	9.942e-34	147.0	COG1538@1|root,COG1538@2|Bacteria,1PDKT@1224|Proteobacteria,4398W@68525|delta/epsilon subdivisions,2X4G7@28221|Deltaproteobacteria,2YYYH@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SHD3_k127_2652351_9	378806.STAUR_0741	1.766e-05	55.0	2AQ8H@1|root,31FEB@2|Bacteria,1Q9XA@1224|Proteobacteria,434NZ@68525|delta/epsilon subdivisions,2WZ0A@28221|Deltaproteobacteria,2Z11X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2652351_1	518766.Rmar_2441	3.018e-219	700.0	COG0591@1|root,COG0591@2|Bacteria,4PKHI@976|Bacteroidetes,1FIMH@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
SHD3_k127_2652351_8	216594.MMAR_3225	2.101e-07	63.0	COG5650@1|root,COG5650@2|Bacteria,2GJBC@201174|Actinobacteria,236FB@1762|Mycobacteriaceae	201174|Actinobacteria	S	phosphatidylinositol metabolic process	-	GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509	-	ko:K13671	-	-	-	-	ko00000,ko01000,ko01003	-	GT87	-	GT87
SHD3_k127_2652351_6	219305.MCAG_01725	1.699e-11	73.0	COG1716@1|root,COG1716@2|Bacteria,2GYEE@201174|Actinobacteria,4DJPZ@85008|Micromonosporales	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
SHD3_k127_2652351_2	234267.Acid_0230	3.732e-95	332.0	COG0220@1|root,COG4797@1|root,COG0220@2|Bacteria,COG4797@2|Bacteria,3Y65M@57723|Acidobacteria	2|Bacteria	J	Methyltransferase type 12	-	GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Glyco_transf_41,MethyTransf_Reg,Methyltransf_12,Methyltransf_25,Methyltransf_31
SHD3_k127_2652351_5	1538295.JY96_10750	2.683e-20	102.0	COG3157@1|root,COG3157@2|Bacteria,1RBTU@1224|Proteobacteria,2VS1N@28216|Betaproteobacteria,1KPBG@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Type VI secretion system effector, Hcp	-	-	-	ko:K11903	ko02025,ko03070,map02025,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	-	-	-	T6SS_HCP
SHD3_k127_2652351_7	471852.Tcur_1848	2.393e-10	72.0	COG4675@1|root,COG4675@2|Bacteria,2I6J3@201174|Actinobacteria	201174|Actinobacteria	S	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
SHD3_k127_2652351_3	391625.PPSIR1_11130	1.012e-43	172.0	COG1262@1|root,COG1262@2|Bacteria,1QADB@1224|Proteobacteria,43503@68525|delta/epsilon subdivisions,2X93Q@28221|Deltaproteobacteria,2Z1R3@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_2653881_9	448385.sce0385	7.243e-06	55.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MZW@68525|delta/epsilon subdivisions,2WIV1@28221|Deltaproteobacteria,2YUVS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PocR
SHD3_k127_2653881_5	1254432.SCE1572_02915	1.872e-88	303.0	COG1100@1|root,COG1100@2|Bacteria,1RCJJ@1224|Proteobacteria,42R57@68525|delta/epsilon subdivisions,2WN5Y@28221|Deltaproteobacteria,2YUYK@29|Myxococcales	28221|Deltaproteobacteria	S	Small GTP-binding protein	-	-	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf
SHD3_k127_2653881_2	331869.BAL199_12336	3.431e-140	458.0	COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,2TR4H@28211|Alphaproteobacteria,4BPAJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	argininosuccinate lyase	argH	GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
SHD3_k127_2653881_0	1254432.SCE1572_02920	1.094e-174	568.0	COG0699@1|root,COG0699@2|Bacteria,1MXBK@1224|Proteobacteria,42PVB@68525|delta/epsilon subdivisions,2WIMK@28221|Deltaproteobacteria,2YZ8C@29|Myxococcales	28221|Deltaproteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SHD3_k127_2653881_4	1254432.SCE1572_02925	6.471e-119	389.0	COG0501@1|root,COG0501@2|Bacteria,1NG7Y@1224|Proteobacteria,439MR@68525|delta/epsilon subdivisions,2X4YW@28221|Deltaproteobacteria,2YZV7@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SHD3_k127_2653881_6	1123354.AUDR01000012_gene1779	9.176e-72	248.0	COG0560@1|root,COG0560@2|Bacteria,1MZPG@1224|Proteobacteria,2VHDT@28216|Betaproteobacteria	28216|Betaproteobacteria	E	phosphoserine phosphatase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
SHD3_k127_2653881_3	981369.JQMJ01000004_gene1279	1.635e-137	450.0	COG0673@1|root,COG0673@2|Bacteria,2GJNE@201174|Actinobacteria,2NF66@228398|Streptacidiphilus	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA,GFO_IDH_MocA_C
SHD3_k127_2653881_1	667014.Thein_0206	4.282e-155	508.0	COG2262@1|root,COG2262@2|Bacteria,2GH9H@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
SHD3_k127_2653881_7	378806.STAUR_4903	1.646e-71	251.0	COG0524@1|root,COG0524@2|Bacteria,1Q2QX@1224|Proteobacteria,438CG@68525|delta/epsilon subdivisions,2X3MS@28221|Deltaproteobacteria,2YWJA@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SHD3_k127_2653881_8	1254432.SCE1572_30720	1.401e-25	107.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YU4F@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SHD3_k127_2654749_2	1227349.C170_28823	2.314e-10	74.0	COG1879@1|root,COG1879@2|Bacteria,1TSBH@1239|Firmicutes,4HEG2@91061|Bacilli,274YU@186822|Paenibacillaceae	91061|Bacilli	G	ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SHD3_k127_2654749_1	344747.PM8797T_30731	8.013e-69	256.0	COG1105@1|root,COG1105@2|Bacteria,2J14C@203682|Planctomycetes	203682|Planctomycetes	H	COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)	-	-	2.7.1.144	ko:K00917	ko00052,ko01100,map00052,map01100	-	R03236	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SHD3_k127_2654749_0	1123073.KB899243_gene775	3.699e-102	336.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,1S2TQ@1236|Gammaproteobacteria,1X4M1@135614|Xanthomonadales	135614|Xanthomonadales	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SHD3_k127_2654749_3	383372.Rcas_0264	1.289e-06	53.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_265720_14	768671.ThimaDRAFT_3025	1.022e-18	90.0	COG2442@1|root,COG2442@2|Bacteria,1P47Y@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SHD3_k127_265720_13	794903.OPIT5_19320	2.855e-26	115.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
SHD3_k127_265720_4	886293.Sinac_6637	2.064e-89	305.0	COG1163@1|root,COG1163@2|Bacteria,2IWYP@203682|Planctomycetes	203682|Planctomycetes	S	TGS domain	-	-	-	ko:K06944	-	-	-	-	ko00000	-	-	-	MMR_HSR1,TGS
SHD3_k127_265720_1	1192034.CAP_8397	5.869e-161	524.0	COG0595@1|root,COG0595@2|Bacteria,1MUGV@1224|Proteobacteria,42M65@68525|delta/epsilon subdivisions,2WIQ9@28221|Deltaproteobacteria,2YXJ9@29|Myxococcales	28221|Deltaproteobacteria	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
SHD3_k127_265720_10	1192034.CAP_8078	1.178e-39	152.0	COG2947@1|root,COG2947@2|Bacteria,1RHRU@1224|Proteobacteria,42SRT@68525|delta/epsilon subdivisions,2WPB8@28221|Deltaproteobacteria,2YV8N@29|Myxococcales	28221|Deltaproteobacteria	S	EVE domain	-	-	-	-	-	-	-	-	-	-	-	-	EVE
SHD3_k127_265720_16	483219.LILAB_18920	5.744e-08	64.0	COG2319@1|root,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria	1224|Proteobacteria	LO	WD-40 repeat	-	-	-	ko:K20332	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	NACHT,Pentapeptide,WD40
SHD3_k127_265720_17	66897.DJ64_13605	8.356e-05	55.0	COG5542@1|root,COG5542@2|Bacteria,2GJQF@201174|Actinobacteria	201174|Actinobacteria	NT	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_265720_5	1237149.C900_02500	2.176e-78	267.0	COG2085@1|root,COG2085@2|Bacteria,4NQ1G@976|Bacteroidetes,47Q30@768503|Cytophagia	976|Bacteroidetes	S	NADP oxidoreductase coenzyme F420-dependent	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SHD3_k127_265720_6	1242864.D187_004030	8.161e-72	250.0	COG3325@1|root,COG3325@2|Bacteria,1RHPN@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_265720_18	1229780.BN381_20068	0.0003356	53.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH,HNH_4
SHD3_k127_265720_2	937777.Deipe_1849	1.927e-151	484.0	COG0451@1|root,COG0451@2|Bacteria,1WM05@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	GM	PFAM NAD dependent epimerase dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SHD3_k127_265720_3	448385.sce7406	6.345e-136	459.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YV0J@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SHD3_k127_265720_12	448385.sce9086	8.852e-36	147.0	COG0526@1|root,COG0526@2|Bacteria,1N726@1224|Proteobacteria,42U61@68525|delta/epsilon subdivisions,2WQRF@28221|Deltaproteobacteria,2YVYE@29|Myxococcales	28221|Deltaproteobacteria	CO	Redoxin	dsbE	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
SHD3_k127_265720_9	1304875.JAFZ01000001_gene1344	1.23e-41	163.0	COG1968@1|root,COG1968@2|Bacteria,3TAU6@508458|Synergistetes	508458|Synergistetes	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SHD3_k127_265720_0	448385.sce0664	0.0	1032.0	COG0556@1|root,COG0556@2|Bacteria,1MUFK@1224|Proteobacteria,42MFA@68525|delta/epsilon subdivisions,2WJ20@28221|Deltaproteobacteria,2YU4B@29|Myxococcales	28221|Deltaproteobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
SHD3_k127_265720_8	1192034.CAP_7474	1.617e-52	188.0	COG0103@1|root,COG0103@2|Bacteria,1RD4A@1224|Proteobacteria,42SVI@68525|delta/epsilon subdivisions,2WP7T@28221|Deltaproteobacteria,2YV9P@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
SHD3_k127_265720_7	448385.sce7405	5.517e-56	201.0	COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,42SD5@68525|delta/epsilon subdivisions,2WP5M@28221|Deltaproteobacteria,2YVJG@29|Myxococcales	28221|Deltaproteobacteria	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
SHD3_k127_265720_15	1254432.SCE1572_03085	1.13e-11	68.0	COG0745@1|root,COG3437@1|root,COG3667@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG3667@2|Bacteria,1QXU5@1224|Proteobacteria,43C6N@68525|delta/epsilon subdivisions,2X7GW@28221|Deltaproteobacteria,2YUUA@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HD_5,Response_reg,T2SSE_N
SHD3_k127_2662358_3	1996.JOFO01000006_gene408	0.0007315	52.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_2662358_2	1007103.AFHW01000071_gene5575	2.259e-07	63.0	2DBYB@1|root,2ZBUC@2|Bacteria,1V738@1239|Firmicutes,4HFT2@91061|Bacilli,26UN2@186822|Paenibacillaceae	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2662358_0	472759.Nhal_2807	3.263e-148	482.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1WVY9@135613|Chromatiales	135613|Chromatiales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SHD3_k127_2662358_1	754476.Q7A_3010	1.591e-53	194.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,462AB@72273|Thiotrichales	72273|Thiotrichales	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SHD3_k127_2664380_15	1313172.YM304_10020	1.639e-14	74.0	COG5184@1|root,COG5184@2|Bacteria,2IDH9@201174|Actinobacteria	201174|Actinobacteria	M	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new,RCC1,RCC1_2
SHD3_k127_2664380_4	1047013.AQSP01000133_gene2137	1.589e-99	337.0	COG1172@1|root,COG1172@2|Bacteria,2NPUE@2323|unclassified Bacteria	2|Bacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
SHD3_k127_2664380_3	1499967.BAYZ01000173_gene5799	3.909e-120	393.0	COG1879@1|root,COG1879@2|Bacteria,2NQCX@2323|unclassified Bacteria	2|Bacteria	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
SHD3_k127_2664380_2	1120949.KB903304_gene6929	9.68e-130	428.0	2DP8S@1|root,3311S@2|Bacteria,2IBQV@201174|Actinobacteria,4D9ZS@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2664380_14	1192034.CAP_2433	4.506e-17	96.0	COG4402@1|root,COG4402@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
SHD3_k127_2664380_7	1254432.SCE1572_20810	4.313e-55	199.0	COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,42TMP@68525|delta/epsilon subdivisions,2WR9C@28221|Deltaproteobacteria,2YV89@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family UPF0047	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SHD3_k127_2664380_10	1254432.SCE1572_38630	2.731e-32	139.0	COG1187@1|root,COG1295@1|root,COG1187@2|Bacteria,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	rluB	-	5.4.99.22	ko:K06178,ko:K07058	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4,Virul_fac_BrkB
SHD3_k127_2664380_0	1192034.CAP_2009	2.131e-221	706.0	COG3292@1|root,COG3292@2|Bacteria,1Q3P3@1224|Proteobacteria,439GA@68525|delta/epsilon subdivisions,2X4S8@28221|Deltaproteobacteria,2YZHD@29|Myxococcales	28221|Deltaproteobacteria	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2664380_1	1254432.SCE1572_43840	4.864e-186	600.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S55
SHD3_k127_2664380_5	1242864.D187_005920	4.136e-58	209.0	2AN6Z@1|root,31D4X@2|Bacteria,1QA87@1224|Proteobacteria,434WE@68525|delta/epsilon subdivisions,2WZ7E@28221|Deltaproteobacteria,2Z1HM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2664380_12	1470591.BW41_01325	4.107e-28	123.0	COG3762@1|root,COG3762@2|Bacteria,1R61N@1224|Proteobacteria,2U5XG@28211|Alphaproteobacteria,2K470@204457|Sphingomonadales	204457|Sphingomonadales	S	membrane	-	-	-	ko:K08988	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SHD3_k127_2664380_8	582744.Msip34_2282	8.775e-45	172.0	COG1512@1|root,COG1512@2|Bacteria,1PB41@1224|Proteobacteria,2VMNV@28216|Betaproteobacteria,2KKKF@206350|Nitrosomonadales	206350|Nitrosomonadales	S	TPM domain	-	-	-	ko:K06872	-	-	-	-	ko00000	-	-	-	TPM_phosphatase
SHD3_k127_2664380_6	1217652.F954_00380	2.691e-57	205.0	COG1704@1|root,COG1704@2|Bacteria,1MVH0@1224|Proteobacteria,1RS3E@1236|Gammaproteobacteria,3NK77@468|Moraxellaceae	1236|Gammaproteobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SHD3_k127_2664380_9	402777.KB235903_gene2106	3.13e-37	161.0	COG5635@1|root,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,NACHT
SHD3_k127_2664380_11	502025.Hoch_2222	1.482e-30	139.0	COG0515@1|root,COG1262@1|root,COG1409@1|root,COG5635@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,COG1409@2|Bacteria,COG5635@2|Bacteria,1QZAN@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_2686309_2	485918.Cpin_4843	5.833e-81	277.0	COG1312@1|root,COG1874@1|root,COG1312@2|Bacteria,COG1874@2|Bacteria,4NDX1@976|Bacteroidetes,1IX44@117747|Sphingobacteriia	976|Bacteroidetes	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_35,Glyco_hydro_42
SHD3_k127_2686309_4	1121920.AUAU01000026_gene1475	6.833e-57	220.0	COG0845@1|root,COG0845@2|Bacteria,3Y2XB@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SHD3_k127_2686309_0	1121920.AUAU01000026_gene1474	0.0	1209.0	COG0841@1|root,COG0841@2|Bacteria,3Y35W@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SHD3_k127_2686309_1	1411123.JQNH01000001_gene2515	1.616e-140	475.0	COG0421@1|root,COG0421@2|Bacteria,1N1PJ@1224|Proteobacteria,2TUJQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	MA20_01900	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2691480_1	1144275.COCOR_07596	9.777e-37	145.0	COG3837@1|root,COG3837@2|Bacteria,1N15Q@1224|Proteobacteria,43B73@68525|delta/epsilon subdivisions,2X6KK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SHD3_k127_2691480_2	1121940.AUDZ01000014_gene1123	8.862e-05	53.0	COG0500@1|root,COG2226@2|Bacteria,1PA5F@1224|Proteobacteria,1RY7A@1236|Gammaproteobacteria,1XJ9G@135619|Oceanospirillales	135619|Oceanospirillales	H	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway	bioC	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
SHD3_k127_2691480_0	448385.sce2921	2.469e-299	936.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_7,TPR_8
SHD3_k127_2692137_5	485913.Krac_4022	4.257e-29	119.0	COG2801@1|root,COG2801@2|Bacteria	2|Bacteria	L	transposition	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,LZ_Tnp_IS481,rve_3
SHD3_k127_2692137_7	1242864.D187_004172	9.613e-05	48.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Calx-beta,DUF3616,Kelch_1,Kelch_4,Kelch_6
SHD3_k127_2692137_3	521011.Mpal_0755	6.445e-33	149.0	COG3391@1|root,arCOG03563@2157|Archaea	2157|Archaea	P	NHL repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,HemolysinCabind,NHL,PKD
SHD3_k127_2692137_6	215803.DB30_4298	1.097e-10	76.0	COG4447@1|root,COG4447@2|Bacteria,1PK4F@1224|Proteobacteria,437G7@68525|delta/epsilon subdivisions,2XA3A@28221|Deltaproteobacteria,2YVKV@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2692137_2	1536769.P40081_11680	2.132e-45	189.0	COG3209@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,1V255@1239|Firmicutes,4HFUF@91061|Bacilli,26VZT@186822|Paenibacillaceae	91061|Bacilli	M	40-residue YVTN family beta-propeller repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Collagen,Cytochrom_D1,Lactonase,PD40,Phosphoesterase
SHD3_k127_2692137_4	1133850.SHJG_5074	1.575e-29	120.0	COG2963@1|root,COG2963@2|Bacteria,2IM4Y@201174|Actinobacteria	201174|Actinobacteria	L	PFAM transposase IS3 IS911 family protein	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
SHD3_k127_2692137_0	1254432.SCE1572_06800	1.683e-95	323.0	COG2801@1|root,COG2801@2|Bacteria,1MVXQ@1224|Proteobacteria,42M98@68525|delta/epsilon subdivisions,2WMKB@28221|Deltaproteobacteria,2YXV7@29|Myxococcales	28221|Deltaproteobacteria	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,HTH_Tnp_1,rve
SHD3_k127_2692137_1	483219.LILAB_18230	9.439e-53	196.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Arm-DNA-bind_2,Phage_int_SAM_2,Phage_integrase
SHD3_k127_2700362_1	1192034.CAP_3040	9.187e-149	492.0	COG1360@1|root,COG5316@1|root,COG1360@2|Bacteria,COG5316@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	-	-	-	ko:K11892	ko03070,map03070	M00334	-	-	ko00000,ko00001,ko00002,ko02044	3.A.23.1	-	-	DUF4139,DotU,OmpA
SHD3_k127_2700362_7	502025.Hoch_5735	4.534e-49	181.0	29FS0@1|root,302PP@2|Bacteria,1RE1Q@1224|Proteobacteria,4383H@68525|delta/epsilon subdivisions,2X3DF@28221|Deltaproteobacteria,2YVJ0@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2700362_5	391625.PPSIR1_40645	3.731e-82	287.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2YTVT@29|Myxococcales	28221|Deltaproteobacteria	C	Fe-S oxidoreductases	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_2700362_3	28072.Nos7524_3612	2.176e-109	366.0	COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1HJ2V@1161|Nostocales	1117|Cyanobacteria	C	PFAM Alanine dehydrogenase PNT, C-terminal domain	pntA	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
SHD3_k127_2700362_12	234267.Acid_3374	5.475e-25	111.0	COG3288@1|root,COG3288@2|Bacteria,3Y5PH@57723|Acidobacteria	57723|Acidobacteria	C	4TM region of pyridine nucleotide transhydrogenase, mitoch	-	-	1.6.1.2	ko:K00324	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB_4TM
SHD3_k127_2700362_0	234267.Acid_3373	6.987e-174	562.0	COG1282@1|root,COG1282@2|Bacteria,3Y42H@57723|Acidobacteria	57723|Acidobacteria	C	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane	-	-	1.6.1.2	ko:K00325	ko00760,ko01100,map00760,map01100	-	R00112	RC00001	ko00000,ko00001,ko01000	-	-	-	PNTB
SHD3_k127_2700362_18	292564.Cyagr_1748	0.0008324	47.0	2E9N9@1|root,33N8H@2|Bacteria	2|Bacteria	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SHD3_k127_2700362_11	419947.MRA_2576	3.43e-28	119.0	COG1487@1|root,COG1487@2|Bacteria,2IR5C@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_2700362_15	1192034.CAP_6473	1.103e-07	63.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	DUF1929,Kelch_1,Kelch_4,Kelch_6
SHD3_k127_2700362_16	1463921.JODF01000001_gene3921	1.442e-05	58.0	COG3271@1|root,COG3271@2|Bacteria,2I3GU@201174|Actinobacteria	201174|Actinobacteria	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SHD3_k127_2700362_14	697282.Mettu_2299	7.17e-19	95.0	2CJAT@1|root,32S9N@2|Bacteria,1NJ2X@1224|Proteobacteria,1T545@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM Ethyl tert-butyl ether degradation EthD	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2700362_13	448385.sce0785	5.505e-23	115.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HYR,HtaA,Neocarzinostat
SHD3_k127_2700362_2	1540221.JQNI01000004_gene212	1.65e-119	412.0	COG3405@1|root,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	3.2.1.156	ko:K15531	-	-	-	-	ko00000,ko01000	-	GH8	-	CBM_2,Dockerin_1,Glyco_hydro_8,Polysacc_deac_1
SHD3_k127_2700362_6	448385.sce3328	2.732e-57	213.0	2BWTV@1|root,33WJC@2|Bacteria,1NVPR@1224|Proteobacteria,434NA@68525|delta/epsilon subdivisions,2X8Y8@28221|Deltaproteobacteria,2Z10B@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2700362_4	338966.Ppro_3006	9.538e-88	304.0	COG0642@1|root,COG2205@2|Bacteria,1R7QH@1224|Proteobacteria,42PSC@68525|delta/epsilon subdivisions,2WKFW@28221|Deltaproteobacteria,43SHM@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
SHD3_k127_2700362_17	596153.Alide_3355	0.0005807	52.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,4ACNP@80864|Comamonadaceae	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
SHD3_k127_2700362_9	448385.sce4342	8.959e-39	164.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_2705328_2	1408224.SAMCCGM7_c5024	1.308e-06	61.0	COG2020@1|root,COG2020@2|Bacteria,1R55E@1224|Proteobacteria,2U75X@28211|Alphaproteobacteria,4BJ9F@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1295,ICMT
SHD3_k127_2705328_0	1192034.CAP_5522	6.064e-43	162.0	COG0072@1|root,COG0072@2|Bacteria,1MWKS@1224|Proteobacteria,42M1G@68525|delta/epsilon subdivisions,2WJ7V@28221|Deltaproteobacteria,2YYU4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
SHD3_k127_2713746_1	378806.STAUR_7948	3.203e-39	170.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1QWVY@1224|Proteobacteria,438YB@68525|delta/epsilon subdivisions,2X43T@28221|Deltaproteobacteria,2YY6F@29|Myxococcales	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SHD3_k127_2713746_0	96561.Dole_0398	2.279e-84	296.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,HEAT_2,TetR_C_7,TetR_N
SHD3_k127_2713746_2	1254432.SCE1572_19145	3.88e-20	101.0	COG4447@1|root,COG4447@2|Bacteria,1QX8J@1224|Proteobacteria,43C1P@68525|delta/epsilon subdivisions,2X7CA@28221|Deltaproteobacteria,2YW1N@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR
SHD3_k127_2724702_0	1254432.SCE1572_48480	4.525e-130	439.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2YUX0@29|Myxococcales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SHD3_k127_2724702_3	1254432.SCE1572_48465	3.416e-77	269.0	COG1189@1|root,COG1189@2|Bacteria,1MWP5@1224|Proteobacteria,42R2J@68525|delta/epsilon subdivisions,2WIJ6@28221|Deltaproteobacteria,2YV01@29|Myxococcales	28221|Deltaproteobacteria	J	FtsJ-like methyltransferase	tlyA	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
SHD3_k127_2724702_4	1254432.SCE1572_48310	6.239e-73	258.0	COG1266@1|root,COG1266@2|Bacteria,1QAGW@1224|Proteobacteria,43E11@68525|delta/epsilon subdivisions,2WZDX@28221|Deltaproteobacteria,2Z1XB@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SHD3_k127_2724702_1	1192034.CAP_1669	8.09e-107	357.0	COG0382@1|root,COG0382@2|Bacteria,1MXCM@1224|Proteobacteria,42PEU@68525|delta/epsilon subdivisions,2WNNT@28221|Deltaproteobacteria,2Z2ZE@29|Myxococcales	28221|Deltaproteobacteria	H	UbiA prenyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	UbiA
SHD3_k127_2724702_5	448385.sce8169	9.04e-69	243.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50,2.7.11.1	ko:K08884,ko:K12132,ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
SHD3_k127_2724702_2	1192034.CAP_5373	7.1e-96	334.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,42MQ4@68525|delta/epsilon subdivisions,2WMDT@28221|Deltaproteobacteria,2YUQX@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the CinA family	cinA	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
SHD3_k127_2724702_7	266117.Rxyl_3055	1.537e-17	93.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
SHD3_k127_2724702_6	1192034.CAP_0095	6.403e-58	206.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2YUZD@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SHD3_k127_2724731_5	1192034.CAP_0030	7.553e-53	196.0	COG0424@1|root,COG0424@2|Bacteria,1RH6H@1224|Proteobacteria,42SR7@68525|delta/epsilon subdivisions,2WP65@28221|Deltaproteobacteria,2YVJK@29|Myxococcales	28221|Deltaproteobacteria	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
SHD3_k127_2724731_1	1254432.SCE1572_35335	1.607e-119	403.0	COG1807@1|root,COG1807@2|Bacteria,1RJ20@1224|Proteobacteria,43BAJ@68525|delta/epsilon subdivisions,2X6PS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2724731_6	1254432.SCE1572_35330	9.785e-39	146.0	2CDR8@1|root,32ZSF@2|Bacteria,1NCBG@1224|Proteobacteria,42V4S@68525|delta/epsilon subdivisions,2WSDP@28221|Deltaproteobacteria,2YVN6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2724731_3	1192034.CAP_0033	1.412e-92	314.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2YUWE@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SHD3_k127_2724731_2	861299.J421_3951	1.088e-99	345.0	COG0714@1|root,COG0714@2|Bacteria,1ZT5U@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SHD3_k127_2724731_8	448385.sce5923	9.802e-20	92.0	COG0236@1|root,COG0236@2|Bacteria,1N6RU@1224|Proteobacteria,42V26@68525|delta/epsilon subdivisions,2WQ0Y@28221|Deltaproteobacteria,2Z2KY@29|Myxococcales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	acpP-1	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SHD3_k127_2724731_0	1192034.CAP_0046	4.012e-144	486.0	COG0304@1|root,COG0304@2|Bacteria,1N91E@1224|Proteobacteria,42N4J@68525|delta/epsilon subdivisions,2WIY7@28221|Deltaproteobacteria,2Z361@29|Myxococcales	28221|Deltaproteobacteria	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.179,2.3.1.41	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SHD3_k127_2724731_4	448385.sce5919	3.464e-54	195.0	2BT02@1|root,32N40@2|Bacteria,1Q3JG@1224|Proteobacteria,439CC@68525|delta/epsilon subdivisions,2X4KJ@28221|Deltaproteobacteria,2Z05X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
SHD3_k127_2724731_9	314278.NB231_09623	1.121e-10	70.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,1T3U5@1236|Gammaproteobacteria,1X1MF@135613|Chromatiales	135613|Chromatiales	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp
SHD3_k127_2724731_7	69042.WH5701_02174	3.913e-20	91.0	2DGG3@1|root,32U75@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2733815_0	1254432.SCE1572_51515	8.321e-148	499.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NB-ARC,cNMP_binding
SHD3_k127_2733815_4	296591.Bpro_4104	8.499e-07	57.0	COG1487@1|root,COG1487@2|Bacteria,1RHIX@1224|Proteobacteria,2VRES@28216|Betaproteobacteria,4AG0K@80864|Comamonadaceae	28216|Betaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_2733815_1	1206732.BAGD01000272_gene6033	3.355e-41	162.0	COG4106@1|root,COG4106@2|Bacteria,2GK0K@201174|Actinobacteria,4FZIQ@85025|Nocardiaceae	201174|Actinobacteria	S	Methyltransferase domain	metZ	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_2733815_3	1123256.KB907934_gene2365	2.358e-17	84.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_2733815_2	479434.Sthe_2302	9.211e-39	156.0	COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia	189775|Thermomicrobia	K	cell envelope-related transcriptional attenuator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
SHD3_k127_2763315_2	1300143.CCAV010000002_gene338	3.322e-05	57.0	COG3507@1|root,COG3507@2|Bacteria,4PKXQ@976|Bacteroidetes,1HYKB@117743|Flavobacteriia,3ZPHI@59732|Chryseobacterium	976|Bacteroidetes	G	Carbohydrate binding module (family 6)	xynD_2	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_43
SHD3_k127_2763315_0	1144275.COCOR_02186	4.689e-21	100.0	2C5BM@1|root,32RFE@2|Bacteria,1Q9I2@1224|Proteobacteria,43E05@68525|delta/epsilon subdivisions,2WZBP@28221|Deltaproteobacteria,2Z1SM@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2763315_1	357808.RoseRS_4499	1.799e-16	93.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_2765356_0	1254432.SCE1572_07000	1.655e-86	299.0	COG0639@1|root,COG0639@2|Bacteria,1QEIM@1224|Proteobacteria,4307J@68525|delta/epsilon subdivisions,2WV6F@28221|Deltaproteobacteria,2YVCQ@29|Myxococcales	28221|Deltaproteobacteria	T	COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SHD3_k127_2765356_1	1232410.KI421415_gene3060	1.72e-84	291.0	COG0826@1|root,COG0826@2|Bacteria,1QMCE@1224|Proteobacteria,42PSK@68525|delta/epsilon subdivisions,2WKMU@28221|Deltaproteobacteria,43UGW@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_U32
SHD3_k127_2795051_3	448385.sce1053	2.332e-115	379.0	2ARW7@1|root,31H81@2|Bacteria,1QEXJ@1224|Proteobacteria,439J5@68525|delta/epsilon subdivisions,2X4VQ@28221|Deltaproteobacteria,2YZPU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2795051_4	1464048.JNZS01000018_gene2023	2.079e-112	383.0	COG2730@1|root,COG3469@1|root,COG2730@2|Bacteria,COG3469@2|Bacteria,2HW9X@201174|Actinobacteria,4DB85@85008|Micromonosporales	201174|Actinobacteria	G	Endoglucanase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Cellulase,Glyco_hydro_12
SHD3_k127_2795051_7	448385.sce9005	4.862e-45	179.0	COG1651@1|root,COG1651@2|Bacteria	2|Bacteria	O	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Thioredoxin_4,VKOR
SHD3_k127_2795051_1	448385.sce9004	2.499e-217	706.0	COG0557@1|root,COG0557@2|Bacteria,1MUS6@1224|Proteobacteria,42NHP@68525|delta/epsilon subdivisions,2X6U1@28221|Deltaproteobacteria,2Z35Z@29|Myxococcales	28221|Deltaproteobacteria	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	-	-	3.1.13.1	ko:K01147,ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
SHD3_k127_2795051_5	867845.KI911784_gene134	1.115e-79	277.0	COG0451@1|root,COG0451@2|Bacteria,2G6S4@200795|Chloroflexi,374RT@32061|Chloroflexia	32061|Chloroflexia	M	short-chain dehydrogenase reductase SDR	-	-	5.1.3.6	ko:K08679	ko00520,ko01100,map00520,map01100	-	R01385	RC00289	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SHD3_k127_2795051_2	977880.RALTA_B1364	3.678e-201	651.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,2VK9R@28216|Betaproteobacteria,1K0ZW@119060|Burkholderiaceae	28216|Betaproteobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
SHD3_k127_2795051_0	1382356.JQMP01000004_gene486	0.0	1264.0	COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia	189775|Thermomicrobia	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	APH,Alpha-amylase,Malt_amylase_C
SHD3_k127_2795051_8	472759.Nhal_1244	2.274e-14	72.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SHD3_k127_2809786_2	448385.sce1654	1.093e-46	188.0	COG3170@1|root,COG3170@2|Bacteria,1QX3V@1224|Proteobacteria,43BWB@68525|delta/epsilon subdivisions,2X773@28221|Deltaproteobacteria,2YVT2@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	agmX	-	-	-	-	-	-	-	-	-	-	-	DUF4339,zinc_ribbon_4
SHD3_k127_2809786_0	448385.sce1653	1.988e-172	557.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1RATK@1224|Proteobacteria,42R5C@68525|delta/epsilon subdivisions,2WMZP@28221|Deltaproteobacteria,2YW9T@29|Myxococcales	28221|Deltaproteobacteria	T	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,T2SSE_N,TPR_16,TPR_19,TPR_2,TPR_8
SHD3_k127_2809786_1	1254432.SCE1572_10460	1.806e-153	493.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,42M5Y@68525|delta/epsilon subdivisions,2WIMT@28221|Deltaproteobacteria,2YU84@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
SHD3_k127_2809786_3	1192034.CAP_7169	2.151e-40	152.0	COG0809@1|root,COG0809@2|Bacteria,1MUH3@1224|Proteobacteria,42MMG@68525|delta/epsilon subdivisions,2WJ9W@28221|Deltaproteobacteria,2YUD8@29|Myxococcales	28221|Deltaproteobacteria	F	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
SHD3_k127_2814188_0	1242864.D187_001078	2.896e-123	400.0	COG3868@1|root,COG3868@2|Bacteria,1PIK8@1224|Proteobacteria,4343X@68525|delta/epsilon subdivisions,2X531@28221|Deltaproteobacteria,2Z01F@29|Myxococcales	28221|Deltaproteobacteria	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_114
SHD3_k127_2814188_1	1049564.TevJSym_ah00010	2.625e-62	224.0	COG3291@1|root,COG3868@1|root,COG4257@1|root,COG4409@1|root,COG3291@2|Bacteria,COG3868@2|Bacteria,COG4257@2|Bacteria,COG4409@2|Bacteria,1QWZ9@1224|Proteobacteria,1T30T@1236|Gammaproteobacteria,1JAP8@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	G	Cellulase N-terminal ig-like domain	cel9A	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_10,CBM_2,CelD_N,Glyco_hydro_9,PKD
SHD3_k127_2814188_4	290340.AAur_3937	3.357e-17	90.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,1WA3Q@1268|Micrococcaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_2814188_3	391625.PPSIR1_00085	2.762e-31	136.0	COG3712@1|root,COG3712@2|Bacteria,1PBZ9@1224|Proteobacteria,433U5@68525|delta/epsilon subdivisions,2X3GP@28221|Deltaproteobacteria,2YW0J@29|Myxococcales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,zf-HC2
SHD3_k127_2825966_2	1232410.KI421418_gene2272	5.678e-211	670.0	COG0129@1|root,COG0129@2|Bacteria,1MUTQ@1224|Proteobacteria,42N3P@68525|delta/epsilon subdivisions,2WJB7@28221|Deltaproteobacteria,43U65@69541|Desulfuromonadales	28221|Deltaproteobacteria	EG	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1259	ILVD_EDD
SHD3_k127_2825966_1	395493.BegalDRAFT_0585	1.059e-233	734.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria,45ZW1@72273|Thiotrichales	72273|Thiotrichales	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
SHD3_k127_2825966_0	1071073.KI530536_gene1243	1.135e-295	919.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HETV@91061|Bacilli,1ZPVU@1386|Bacillus	91061|Bacilli	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Glyco_hydro_31
SHD3_k127_2825966_4	1121405.dsmv_0045	1.949e-114	383.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PZJ@68525|delta/epsilon subdivisions,2WMGB@28221|Deltaproteobacteria,2MNPX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SHD3_k127_2825966_5	644966.Tmar_0662	1.393e-68	254.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,3WCQJ@538999|Clostridiales incertae sedis	186801|Clostridia	NU	PFAM Type II IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SHD3_k127_2825966_6	1254432.SCE1572_35200	3.006e-42	169.0	COG0745@1|root,COG0745@2|Bacteria,1RKDZ@1224|Proteobacteria,43F04@68525|delta/epsilon subdivisions,2WYKX@28221|Deltaproteobacteria,2Z1YF@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_2825966_3	448385.sce5906	4.442e-123	417.0	COG1196@1|root,COG1196@2|Bacteria,1Q5CV@1224|Proteobacteria,439J1@68525|delta/epsilon subdivisions,2X4VH@28221|Deltaproteobacteria,2Z08N@29|Myxococcales	28221|Deltaproteobacteria	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2825966_7	448385.sce5905	1.136e-14	79.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YYCD@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SHD3_k127_2835244_0	1267535.KB906767_gene4646	3.772e-154	497.0	COG0626@1|root,COG0626@2|Bacteria,3Y2K5@57723|Acidobacteria,2JHVD@204432|Acidobacteriia	204432|Acidobacteriia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.48,4.4.1.1,4.4.1.2,4.4.1.8	ko:K01739,ko:K01758,ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017,M00338,M00609	R00782,R00999,R01001,R01283,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04930,R04941,R04944,R04945,R04946,R09366	RC00020,RC00056,RC00069,RC00348,RC00382,RC00420,RC00487,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02814,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Cys_Met_Meta_PP
SHD3_k127_2835244_7	215803.DB30_1764	0.0004335	47.0	2DBB3@1|root,2Z85F@2|Bacteria,1N6NI@1224|Proteobacteria,4302P@68525|delta/epsilon subdivisions,2WVHK@28221|Deltaproteobacteria,2YUYS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (4846)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4846
SHD3_k127_2835244_1	1192034.CAP_7335	8.611e-126	430.0	COG1187@1|root,COG2885@1|root,COG1187@2|Bacteria,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,42SM6@68525|delta/epsilon subdivisions,2X3B1@28221|Deltaproteobacteria,2YV6X@29|Myxococcales	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,OmpA
SHD3_k127_2835244_2	246197.MXAN_6468	2.469e-78	273.0	COG0583@1|root,COG0583@2|Bacteria,1MW16@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	ko:K10918	ko05111,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
SHD3_k127_2835244_3	401053.AciPR4_1066	5.637e-68	235.0	COG0302@1|root,COG0302@2|Bacteria,3Y2SP@57723|Acidobacteria,2JIR1@204432|Acidobacteriia	204432|Acidobacteriia	H	TIGRFAM GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
SHD3_k127_2835244_5	397948.Cmaq_0517	4.904e-37	145.0	COG0801@1|root,arCOG07203@2157|Archaea	2157|Archaea	H	Dihydroneopterin aldolase	-	-	-	-	-	-	-	-	-	-	-	-	FolB,HPPK
SHD3_k127_2835244_6	1499967.BAYZ01000145_gene6206	9.076e-31	132.0	COG1539@1|root,COG1539@2|Bacteria,2NQ1A@2323|unclassified Bacteria	2|Bacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folX	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564	1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8	ko:K01633,ko:K07589	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073,R11082	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
SHD3_k127_2835244_4	1499967.BAYZ01000145_gene6207	9.755e-60	214.0	COG1028@1|root,COG1028@2|Bacteria,2NQVU@2323|unclassified Bacteria	2|Bacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.5.1.33	ko:K03793	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
SHD3_k127_2835244_8	926562.Oweho_0965	0.0004424	45.0	COG2204@1|root,COG2204@2|Bacteria,4NE89@976|Bacteroidetes,1HWWK@117743|Flavobacteriia,2PBBX@246874|Cryomorphaceae	976|Bacteroidetes	T	Bacterial regulatory protein, Fis family	zraR	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_2844258_0	1321778.HMPREF1982_04262	3.227e-180	571.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,2688K@186813|unclassified Clostridiales	186801|Clostridia	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SHD3_k127_2844258_2	290397.Adeh_3956	2.068e-30	130.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2844258_1	1254432.SCE1572_32560	6.88e-68	241.0	COG2885@1|root,COG2885@2|Bacteria,1R8DG@1224|Proteobacteria,42NGC@68525|delta/epsilon subdivisions,2WX5K@28221|Deltaproteobacteria,2YXCP@29|Myxococcales	28221|Deltaproteobacteria	M	Domain of unknown function (DUF4398)	ompA2	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
SHD3_k127_2844258_3	1254432.SCE1572_32565	1.949e-13	75.0	2AEYE@1|root,314WB@2|Bacteria,1PUU5@1224|Proteobacteria,434MW@68525|delta/epsilon subdivisions,2WYZA@28221|Deltaproteobacteria,2Z0ZG@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4398)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398
SHD3_k127_2880608_2	1207075.PputUW4_01624	2.119e-144	469.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SHD3_k127_2880608_5	1907.SGLAU_07630	9.667e-89	299.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SHD3_k127_2880608_15	65071.PYU1_T007598	1.473e-20	100.0	28Y4S@1|root,2R4YE@2759|Eukaryota,1MAI5@121069|Pythiales	121069|Pythiales	S	Source PGD	-	-	-	-	-	-	-	-	-	-	-	-	LysE
SHD3_k127_2880608_0	575540.Isop_2400	2.488e-319	992.0	COG1523@1|root,COG1523@2|Bacteria,2IX65@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SHD3_k127_2880608_23	1096546.WYO_2598	0.0008318	51.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,2TSFP@28211|Alphaproteobacteria,1JRP9@119045|Methylobacteriaceae	28211|Alphaproteobacteria	S	ribonuclease BN	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
SHD3_k127_2880608_13	247490.KSU1_D0671	1.889e-29	134.0	COG3848@1|root,COG3848@2|Bacteria	2|Bacteria	GT	kinase activity	-	-	2.7.3.13,2.7.9.1,2.7.9.2	ko:K01006,ko:K01007,ko:K22424	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173,M00374	R00199,R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1080,PEP-utilizers,PPDK_N
SHD3_k127_2880608_21	189426.PODO_09695	2.196e-05	55.0	COG1670@1|root,COG1670@2|Bacteria,1V5D0@1239|Firmicutes,4HFTD@91061|Bacilli,26WBV@186822|Paenibacillaceae	91061|Bacilli	J	GNAT family acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SHD3_k127_2880608_17	1144275.COCOR_03766	3.434e-14	87.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,1P5GC@1224|Proteobacteria,433PX@68525|delta/epsilon subdivisions,2WYIK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
SHD3_k127_2880608_14	1151117.AJLF01000002_gene183	8.22e-27	128.0	COG4945@1|root,arCOG03771@2157|Archaea,2Y6JH@28890|Euryarchaeota,244RF@183968|Thermococci	183968|Thermococci	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2880608_4	1254432.SCE1572_00355	1.253e-111	381.0	COG1167@1|root,COG1167@2|Bacteria,1MV6F@1224|Proteobacteria,42MCR@68525|delta/epsilon subdivisions,2WJXI@28221|Deltaproteobacteria,2YY6G@29|Myxococcales	28221|Deltaproteobacteria	EK	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	lysN	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SHD3_k127_2880608_10	485918.Cpin_6099	5.23e-36	142.0	2DW65@1|root,32V0W@2|Bacteria,4NUH7@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2880608_9	290397.Adeh_0987	3.801e-40	155.0	2B7KW@1|root,320RZ@2|Bacteria,1RFFB@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2880608_18	1380394.JADL01000004_gene5861	7.92e-11	72.0	2C3CF@1|root,32RRR@2|Bacteria,1MZUG@1224|Proteobacteria,2UC1Q@28211|Alphaproteobacteria,2JXM9@204441|Rhodospirillales	204441|Rhodospirillales	S	Protein of unknown function (DUF3175)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3175
SHD3_k127_2880608_6	351160.RCIX2633	8.61e-76	266.0	COG0604@1|root,arCOG01458@2157|Archaea,2XURG@28890|Euryarchaeota,2N9N6@224756|Methanomicrobia	224756|Methanomicrobia	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SHD3_k127_2880608_3	204669.Acid345_3624	4.815e-132	429.0	COG1633@1|root,COG1633@2|Bacteria,3Y42J@57723|Acidobacteria,2JM0I@204432|Acidobacteriia	204432|Acidobacteriia	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SHD3_k127_2880608_19	573065.Astex_3152	1.512e-09	64.0	2E3KF@1|root,32YIQ@2|Bacteria,1NC3P@1224|Proteobacteria,2UJDH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2880608_11	1123072.AUDH01000015_gene2140	3.676e-33	138.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,2U9N6@28211|Alphaproteobacteria,2JSQS@204441|Rhodospirillales	204441|Rhodospirillales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
SHD3_k127_2880608_7	404589.Anae109_2572	8.442e-70	244.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria,2YZAW@29|Myxococcales	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SHD3_k127_2880608_12	1254432.SCE1572_04385	2.849e-31	130.0	COG2885@1|root,COG2885@2|Bacteria,1QAG8@1224|Proteobacteria,4352E@68525|delta/epsilon subdivisions,2WZDB@28221|Deltaproteobacteria,2Z1W3@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SHD3_k127_2880608_1	1254432.SCE1572_09725	8.093e-231	732.0	COG5297@1|root,COG5297@2|Bacteria,1NRKN@1224|Proteobacteria,43EDP@68525|delta/epsilon subdivisions,2X82I@28221|Deltaproteobacteria,2YWBM@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2880608_8	1254432.SCE1572_23885	6.775e-45	166.0	COG3507@1|root,COG3507@2|Bacteria,1R3V6@1224|Proteobacteria,43A5N@68525|delta/epsilon subdivisions,2X50Q@28221|Deltaproteobacteria,2YZY6@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.99	ko:K06113	-	-	-	-	ko00000,ko01000	-	GH43	-	Glyco_hydro_43
SHD3_k127_2886614_3	391625.PPSIR1_34257	1.076e-48	188.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2Z1F1@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_2886614_1	543632.JOJL01000028_gene40	5.843e-96	323.0	COG0451@1|root,COG0451@2|Bacteria,2GN2J@201174|Actinobacteria,4DHR9@85008|Micromonosporales	201174|Actinobacteria	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,NAD_binding_10
SHD3_k127_2886614_4	391625.PPSIR1_15530	2.496e-41	164.0	KOG4143@1|root,344U3@2|Bacteria	2|Bacteria	O	ERG2 and Sigma1 receptor like protein	-	-	-	ko:K20719	-	-	-	-	ko00000,ko02000	8.A.63.1.1	-	-	ERG2_Sigma1R
SHD3_k127_2886614_2	1206743.BAGM01000101_gene2583	3.379e-52	202.0	COG0300@1|root,COG0300@2|Bacteria,2I8RA@201174|Actinobacteria,4G0CF@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
SHD3_k127_2886614_0	204669.Acid345_3014	1.303e-125	443.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_2886614_5	903818.KI912268_gene1481	5.184e-29	132.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
SHD3_k127_2901847_5	1089544.KB912942_gene1816	3.207e-06	54.0	COG0657@1|root,COG0657@2|Bacteria,2I97E@201174|Actinobacteria,4E86Q@85010|Pseudonocardiales	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
SHD3_k127_2901847_2	1254432.SCE1572_51055	1.9e-91	316.0	COG2730@1|root,COG2730@2|Bacteria,1R5GC@1224|Proteobacteria,434P8@68525|delta/epsilon subdivisions,2WZ0H@28221|Deltaproteobacteria,2Z12C@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_2901847_0	1195236.CTER_0514	1.717e-143	470.0	COG5301@1|root,COG5301@2|Bacteria,1V0GR@1239|Firmicutes,24F1N@186801|Clostridia	186801|Clostridia	S	PFAM Dockerin type	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,SASA
SHD3_k127_2901847_1	941824.TCEL_01823	5.713e-134	437.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,36EE0@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SHD3_k127_2901847_4	1297742.A176_04938	1.792e-30	124.0	COG1846@1|root,COG1846@2|Bacteria,1N6T5@1224|Proteobacteria,436X8@68525|delta/epsilon subdivisions,2X1MH@28221|Deltaproteobacteria,2Z1NA@29|Myxococcales	28221|Deltaproteobacteria	K	Winged helix-turn-helix DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SHD3_k127_2901847_3	1304880.JAGB01000003_gene1291	2.886e-43	174.0	COG1274@1|root,COG1274@2|Bacteria,1TQED@1239|Firmicutes,249NP@186801|Clostridia	186801|Clostridia	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SHD3_k127_2914795_8	767434.Fraau_0357	2.015e-21	96.0	COG2020@1|root,COG2020@2|Bacteria,1N936@1224|Proteobacteria,1SCXB@1236|Gammaproteobacteria,1X823@135614|Xanthomonadales	135614|Xanthomonadales	O	Methyltransferase	-	-	2.1.1.100	ko:K00587	ko00900,ko01130,map00900,map01130	-	R04496	RC00003,RC00460	ko00000,ko00001,ko01000	-	-	-	PEMT
SHD3_k127_2914795_6	1300345.LF41_610	6.251e-48	194.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,1S0D5@1236|Gammaproteobacteria,1XCC6@135614|Xanthomonadales	135614|Xanthomonadales	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12
SHD3_k127_2914795_3	1254432.SCE1572_26190	4.57e-101	353.0	COG0515@1|root,COG0515@2|Bacteria,1Q1TQ@1224|Proteobacteria,437GN@68525|delta/epsilon subdivisions,2X2PF@28221|Deltaproteobacteria,2YYUJ@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_2914795_4	1192034.CAP_8241	2.23e-98	340.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42R8X@68525|delta/epsilon subdivisions,2WN6U@28221|Deltaproteobacteria,2YWMS@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SHD3_k127_2914795_2	1254432.SCE1572_15100	3.631e-133	445.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,43AYZ@68525|delta/epsilon subdivisions,2X6D8@28221|Deltaproteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	BON,OMP_b-brl,OmpA
SHD3_k127_2914795_1	1254432.SCE1572_48640	1.211e-213	686.0	COG2199@1|root,COG2203@1|root,COG2203@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42PVX@68525|delta/epsilon subdivisions,2WIJ8@28221|Deltaproteobacteria,2Z2WU@29|Myxococcales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF
SHD3_k127_2914795_0	448385.sce6464	0.0	1019.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,42NF1@68525|delta/epsilon subdivisions,2WK52@28221|Deltaproteobacteria,2YUP8@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the heat shock protein 70 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3731,HSP70
SHD3_k127_2914795_5	85643.Tmz1t_3623	2.069e-56	213.0	COG0266@1|root,COG0266@2|Bacteria,1MVM5@1224|Proteobacteria,2VI10@28216|Betaproteobacteria,2KVBM@206389|Rhodocyclales	206389|Rhodocyclales	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
SHD3_k127_291746_0	1254432.SCE1572_31735	4.923e-69	265.0	COG1609@1|root,COG2208@1|root,COG1609@2|Bacteria,COG2208@2|Bacteria,1RHRV@1224|Proteobacteria,43ARR@68525|delta/epsilon subdivisions,2X65U@28221|Deltaproteobacteria,2Z0U1@29|Myxococcales	28221|Deltaproteobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3,SpoIIE
SHD3_k127_291746_1	395494.Galf_1307	4.911e-17	96.0	COG0642@1|root,COG0784@1|root,COG3850@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG3850@2|Bacteria,1NRP8@1224|Proteobacteria,2VJVN@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE5,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
SHD3_k127_291746_2	502025.Hoch_0364	9.9e-12	72.0	COG3509@1|root,COG3509@2|Bacteria,1PI9N@1224|Proteobacteria,439C2@68525|delta/epsilon subdivisions,2X4K6@28221|Deltaproteobacteria,2YVGR@29|Myxococcales	28221|Deltaproteobacteria	Q	Carbohydrate family 9 binding domain-like	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1
SHD3_k127_291746_3	572477.Alvin_1539	4.448e-07	58.0	COG4637@1|root,COG4637@2|Bacteria,1R63Q@1224|Proteobacteria,1TK7D@1236|Gammaproteobacteria,1X068@135613|Chromatiales	135613|Chromatiales	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
SHD3_k127_2919574_2	1254432.SCE1572_43780	1.221e-108	361.0	COG0189@1|root,COG0189@2|Bacteria,1MVUA@1224|Proteobacteria,42SG1@68525|delta/epsilon subdivisions,2WP1E@28221|Deltaproteobacteria,2YUU8@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the prokaryotic GSH synthase family	gshB	-	6.3.2.3	ko:K01920	ko00270,ko00480,ko01100,map00270,map00480,map01100	M00118	R00497,R10994	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	GSH-S_ATP,GSH-S_N
SHD3_k127_2919574_11	380394.Lferr_1525	8.987e-10	62.0	COG1275@1|root,COG1275@2|Bacteria,1MXP2@1224|Proteobacteria,1RR76@1236|Gammaproteobacteria,2NCT2@225057|Acidithiobacillales	225057|Acidithiobacillales	P	C4-dicarboxylate transporter malic acid transport protein	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
SHD3_k127_2919574_12	247490.KSU1_D0632	1.428e-06	55.0	COG1275@1|root,COG1275@2|Bacteria,2J2HB@203682|Planctomycetes	203682|Planctomycetes	P	Voltage-dependent anion channel	-	-	-	-	-	-	-	-	-	-	-	-	SLAC1
SHD3_k127_2919574_3	1254432.SCE1572_22680	1.152e-59	225.0	COG3511@1|root,COG3511@2|Bacteria,1MWVP@1224|Proteobacteria,43347@68525|delta/epsilon subdivisions,2X4FK@28221|Deltaproteobacteria,2YYXB@29|Myxococcales	28221|Deltaproteobacteria	M	Phosphoesterase family	-	-	3.1.4.3	ko:K01114	ko00562,ko00564,ko00565,ko01100,ko01110,ko02024,ko04919,map00562,map00564,map00565,map01100,map01110,map02024,map04919	-	R01312,R02027,R02052,R03332,R07381	RC00017,RC00425	ko00000,ko00001,ko01000,ko02042	-	-	-	Phosphoesterase
SHD3_k127_2919574_0	113395.AXAI01000029_gene2715	7.802e-223	713.0	COG3408@1|root,COG3408@2|Bacteria,1QQ0U@1224|Proteobacteria,2U25D@28211|Alphaproteobacteria,3JWEZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	G	Trehalase	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SHD3_k127_2919574_1	448385.sce5241	4.136e-217	719.0	COG0402@1|root,COG1506@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_2919574_8	215803.DB30_3870	1.959e-18	95.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2X240@28221|Deltaproteobacteria,2YZXU@29|Myxococcales	28221|Deltaproteobacteria	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_2919574_9	448385.sce1487	2.797e-18	97.0	COG0457@1|root,COG0457@2|Bacteria,1QB30@1224|Proteobacteria,43E53@68525|delta/epsilon subdivisions,2WZRF@28221|Deltaproteobacteria,2Z2KD@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2919574_10	1254432.SCE1572_09715	2.039e-10	64.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_2923045_2	946483.Cenrod_0134	1.26e-66	230.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VJJU@28216|Betaproteobacteria,4ACRH@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SHD3_k127_2923045_3	946483.Cenrod_0134	2.408e-63	222.0	COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VJJU@28216|Betaproteobacteria,4ACRH@80864|Comamonadaceae	28216|Betaproteobacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SHD3_k127_2923045_1	946483.Cenrod_0133	2.53e-169	552.0	COG0747@1|root,COG0747@2|Bacteria,1N4PK@1224|Proteobacteria	1224|Proteobacteria	E	ABC-type dipeptide transport system periplasmic component	VVA0132	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
SHD3_k127_2923045_0	1254432.SCE1572_15045	6.528e-202	658.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SHD3_k127_2923045_6	102232.GLO73106DRAFT_00001180	1.185e-06	54.0	2BCFE@1|root,32611@2|Bacteria,1G6WH@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_5
SHD3_k127_2923045_7	65672.G4TM19	3.638e-05	56.0	29R3V@1|root,2RXA6@2759|Eukaryota,39U1P@33154|Opisthokonta,3P08U@4751|Fungi,3VCFF@5204|Basidiomycota,22FCM@155619|Agaricomycetes	4751|Fungi	G	Glycosyl hydrolase family 45	-	-	-	-	-	-	-	-	-	-	-	-	CBM_1,Glyco_hydro_45
SHD3_k127_2923045_9	543734.LCABL_30140	0.0006984	51.0	COG0596@1|root,COG0596@2|Bacteria,1V02M@1239|Firmicutes,4HN2K@91061|Bacilli,3FBGC@33958|Lactobacillaceae	91061|Bacilli	S	Alpha/beta hydrolase family	-	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1,Hydrolase_4
SHD3_k127_2923045_8	1029824.AFID01000007_gene1070	9.669e-05	54.0	COG0741@1|root,COG1388@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,2IBV1@201174|Actinobacteria,1W7WW@1268|Micrococcaceae	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM,SLT
SHD3_k127_2923045_5	448385.sce5493	3.565e-24	113.0	2AN2E@1|root,31CZZ@2|Bacteria,1QA0W@1224|Proteobacteria,434RF@68525|delta/epsilon subdivisions,2WZ2M@28221|Deltaproteobacteria,2Z16X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11
SHD3_k127_2930132_1	1192034.CAP_6467	2.489e-89	332.0	COG1262@1|root,COG1361@1|root,COG3055@1|root,COG5184@1|root,COG1262@2|Bacteria,COG1361@2|Bacteria,COG3055@2|Bacteria,COG5184@2|Bacteria,1Q2FP@1224|Proteobacteria,4381R@68525|delta/epsilon subdivisions,2X3BT@28221|Deltaproteobacteria,2YVB5@29|Myxococcales	28221|Deltaproteobacteria	DZ	Homologues of snake disintegrins	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2930132_3	448385.sce6396	5.483e-34	153.0	COG1520@1|root,COG1520@2|Bacteria,1P0W9@1224|Proteobacteria	1224|Proteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2930132_5	1201290.M902_2354	8.514e-22	98.0	COG3093@1|root,COG3093@2|Bacteria,1N76J@1224|Proteobacteria,42WQS@68525|delta/epsilon subdivisions,2MUEY@213481|Bdellovibrionales,2WRPT@28221|Deltaproteobacteria	213481|Bdellovibrionales	K	Helix-turn-helix XRE-family like proteins	higA	-	-	ko:K21498	-	-	-	-	ko00000,ko02048	-	-	-	HTH_3
SHD3_k127_2930132_4	314254.OA2633_05341	6.067e-30	122.0	COG3549@1|root,COG3549@2|Bacteria,1MZKX@1224|Proteobacteria,2UBQF@28211|Alphaproteobacteria,43YJJ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	RelE-like toxin of type II toxin-antitoxin system HigB	-	-	-	ko:K07334	-	-	-	-	ko00000,ko02048	-	-	-	HigB-like_toxin
SHD3_k127_293607_6	1047013.AQSP01000133_gene2141	9.3e-23	105.0	COG2605@1|root,COG2605@2|Bacteria	2|Bacteria	G	GHMP kinase	fkp	-	2.7.1.52	ko:K05305	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R03161	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	Fucokinase,GHMP_kinases_C,GHMP_kinases_N
SHD3_k127_293607_5	269799.Gmet_0042	4.018e-41	160.0	COG1878@1|root,COG1878@2|Bacteria,1P8U5@1224|Proteobacteria,42SY1@68525|delta/epsilon subdivisions,2WPQ7@28221|Deltaproteobacteria,43V12@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
SHD3_k127_293607_3	404589.Anae109_0513	3.763e-86	292.0	COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,42MMJ@68525|delta/epsilon subdivisions,2WK7X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KO	TIGRFAM Hydrogenase accessory protein HypB	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
SHD3_k127_293607_7	404589.Anae109_0514	2.28e-17	95.0	COG0375@1|root,COG0375@2|Bacteria,1MZJH@1224|Proteobacteria,42TGG@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Probably plays a role in a hydrogenase nickel cofactor insertion step	hypA	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
SHD3_k127_293607_1	378806.STAUR_1796	9.601e-157	511.0	COG1232@1|root,COG1232@2|Bacteria,1QX5M@1224|Proteobacteria,42VK0@68525|delta/epsilon subdivisions,2WRXR@28221|Deltaproteobacteria,2YUYX@29|Myxococcales	28221|Deltaproteobacteria	H	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SHD3_k127_293607_9	1192034.CAP_1496	3.707e-15	84.0	2DI1Z@1|root,301RV@2|Bacteria,1NM7Q@1224|Proteobacteria,433HJ@68525|delta/epsilon subdivisions,2WXZG@28221|Deltaproteobacteria,2Z1QD@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of Unknown Function (DUF350)	-	-	-	-	-	-	-	-	-	-	-	-	DUF350
SHD3_k127_293607_2	379066.GAU_3057	4.099e-149	488.0	COG4262@1|root,COG4262@2|Bacteria,1ZU7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_293607_10	1278073.MYSTI_00775	5.529e-14	86.0	COG0612@1|root,COG0612@2|Bacteria,1MU6R@1224|Proteobacteria,4315B@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Insulinase (Peptidase family M16)	MA20_05660	-	2.7.7.6	ko:K00960,ko:K07263,ko:K07623	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_293607_0	309801.trd_1815	0.0	1286.0	COG0209@1|root,COG0209@2|Bacteria,2G8RN@200795|Chloroflexi,27Y2V@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SHD3_k127_293607_12	1123256.KB907934_gene2365	5.494e-10	67.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_293607_8	1254432.SCE1572_02890	2.66e-15	79.0	COG0209@1|root,COG0209@2|Bacteria,1MUJ8@1224|Proteobacteria,42N8M@68525|delta/epsilon subdivisions,2WJRT@28221|Deltaproteobacteria,2YUBZ@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdA1	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
SHD3_k127_293607_13	1121935.AQXX01000098_gene1655	0.0002837	50.0	COG3637@1|root,COG3637@2|Bacteria,1RDPZ@1224|Proteobacteria,1S4GQ@1236|Gammaproteobacteria,1XP8B@135619|Oceanospirillales	135619|Oceanospirillales	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SHD3_k127_293607_11	1297742.A176_06726	1.718e-11	75.0	COG4935@1|root,COG5184@1|root,COG4935@2|Bacteria,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,RCC1
SHD3_k127_293607_4	1303518.CCALI_01467	1.358e-56	212.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	exsH	-	3.2.1.178,3.2.1.18,3.2.1.52	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	M00079	R00022,R04018,R06004,R11316	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	-	GH16,GH20,GH33	-	CBM_4_9,Glyco_hydro_16
SHD3_k127_2940817_3	1254432.SCE1572_09715	2.097e-37	147.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_2940817_4	448385.sce1487	3.568e-16	91.0	COG0457@1|root,COG0457@2|Bacteria,1QB30@1224|Proteobacteria,43E53@68525|delta/epsilon subdivisions,2WZRF@28221|Deltaproteobacteria,2Z2KD@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2940817_2	1267535.KB906767_gene2997	1.515e-103	345.0	COG4279@1|root,COG4279@2|Bacteria,3Y8KE@57723|Acidobacteria	57723|Acidobacteria	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
SHD3_k127_2940817_0	1267535.KB906767_gene2998	0.0	1230.0	COG0553@1|root,COG0553@2|Bacteria,3Y61F@57723|Acidobacteria	57723|Acidobacteria	L	SNF2 Helicase protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
SHD3_k127_2940817_1	1122927.KB895419_gene2538	8.09e-202	653.0	COG0265@1|root,COG4099@1|root,COG0265@2|Bacteria,COG4099@2|Bacteria,1UNX7@1239|Firmicutes,4IUTQ@91061|Bacilli,2707B@186822|Paenibacillaceae	91061|Bacilli	O	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2943559_5	443144.GM21_0021	5.378e-79	271.0	COG0543@1|root,COG0543@2|Bacteria,1NTWI@1224|Proteobacteria,42M66@68525|delta/epsilon subdivisions,2WJJ2@28221|Deltaproteobacteria,43U7N@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	oxidoreductase FAD NAD(P)-binding domain protein	nfnB	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
SHD3_k127_2943559_1	243231.GSU3057	8.987e-181	577.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJHC@28221|Deltaproteobacteria,43UJI@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	nfnA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
SHD3_k127_2943559_9	448385.sce9012	7.913e-32	135.0	COG1716@1|root,COG1716@2|Bacteria,1PEBF@1224|Proteobacteria,433IZ@68525|delta/epsilon subdivisions,2WXWM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_2943559_3	215803.DB30_7940	1.588e-104	361.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X7DF@28221|Deltaproteobacteria,2YY2W@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_2943559_4	1192034.CAP_3357	2.121e-98	341.0	COG0515@1|root,COG0515@2|Bacteria,1Q38J@1224|Proteobacteria,438ZJ@68525|delta/epsilon subdivisions,2X44T@28221|Deltaproteobacteria,2YY98@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	masK	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_2943559_2	1192034.CAP_3392	2.327e-136	447.0	COG1570@1|root,COG1570@2|Bacteria,1MUA4@1224|Proteobacteria,42MSB@68525|delta/epsilon subdivisions,2WJI6@28221|Deltaproteobacteria,2YV21@29|Myxococcales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
SHD3_k127_2943559_6	1192034.CAP_3372	8.607e-74	259.0	COG2804@1|root,COG2804@2|Bacteria	2|Bacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE_N
SHD3_k127_2943559_0	448385.sce2470	2.746e-274	870.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUQ6@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,Pkinase,TPR_12,zinc_ribbon_2
SHD3_k127_2943559_8	1254432.SCE1572_14820	6.458e-59	213.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,431UR@68525|delta/epsilon subdivisions,2WWZQ@28221|Deltaproteobacteria,2YU65@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
SHD3_k127_2945604_3	391625.PPSIR1_39020	4.15e-13	70.0	COG0631@1|root,COG0631@2|Bacteria,1MVE7@1224|Proteobacteria,43AG6@68525|delta/epsilon subdivisions,2X63V@28221|Deltaproteobacteria,2Z38Y@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090	-	-	-	-	ko00000,ko01000	-	-	-	PP2C_2
SHD3_k127_2945604_0	886293.Sinac_3678	1.978e-49	202.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BNR,Pep_M12B_propep,Reprolysin_5,Sortilin-Vps10
SHD3_k127_2945604_1	760568.Desku_1009	3.036e-46	173.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,2620R@186807|Peptococcaceae	186801|Clostridia	S	DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SHD3_k127_2945604_2	243233.MCA2830	8.504e-27	114.0	COG0531@1|root,COG0531@2|Bacteria,1MXNJ@1224|Proteobacteria,1RY8P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	amino acid	frlA	GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039	-	ko:K03294,ko:K19540	-	-	-	-	ko00000,ko02000	2.A.3.2,2.A.3.8.17	-	iAF1260.b3370,iB21_1397.B21_03173,iBWG_1329.BWG_3062,iEC042_1314.EC042_3632,iEC55989_1330.EC55989_3776,iECBD_1354.ECBD_0378,iECB_1328.ECB_03221,iECDH10B_1368.ECDH10B_3546,iECDH1ME8569_1439.ECDH1ME8569_3250,iECD_1391.ECD_03221,iECIAI1_1343.ECIAI1_3509,iECO111_1330.ECO111_4180,iECO26_1355.ECO26_4459,iETEC_1333.ETEC_3621,iEcDH1_1363.EcDH1_0342,iJO1366.b3370,iSSON_1240.SSON_3502,iUMNK88_1353.UMNK88_4136,iY75_1357.Y75_RS20365	AA_permease_2
SHD3_k127_2951418_5	1123277.KB893195_gene5768	1.414e-09	65.0	COG0702@1|root,COG0702@2|Bacteria,4NMI5@976|Bacteroidetes,47R0K@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SHD3_k127_2951418_4	1278073.MYSTI_01582	2.911e-17	92.0	COG2730@1|root,COG5549@1|root,COG2730@2|Bacteria,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_6,F5_F8_type_C,Peptidase_M57
SHD3_k127_2951418_2	1220534.B655_2396	4.831e-35	151.0	COG2020@1|root,arCOG03580@2157|Archaea,2Y4MT@28890|Euryarchaeota	28890|Euryarchaeota	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	ICMT
SHD3_k127_2951418_3	1123008.KB905694_gene1580	5.312e-19	95.0	COG1309@1|root,COG1309@2|Bacteria,4NU6H@976|Bacteroidetes	976|Bacteroidetes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_2951418_7	452652.KSE_27970	0.000392	44.0	COG3631@1|root,COG3631@2|Bacteria,2IJQH@201174|Actinobacteria	201174|Actinobacteria	S	Limonene-1,2-epoxide hydrolase catalytic domain	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
SHD3_k127_2951418_1	1286171.EAL2_c07490	4.152e-167	539.0	COG0277@1|root,COG0277@2|Bacteria,1VPB2@1239|Firmicutes	1239|Firmicutes	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4
SHD3_k127_2951418_0	744872.Spica_0555	0.0	1433.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,2J5ZA@203691|Spirochaetes	203691|Spirochaetes	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
SHD3_k127_2952984_29	1089553.Tph_c25870	3.15e-14	72.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,42EPJ@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SHD3_k127_2952984_13	1192034.CAP_0438	1.107e-54	193.0	COG0051@1|root,COG0051@2|Bacteria,1RGWF@1224|Proteobacteria,42SE4@68525|delta/epsilon subdivisions,2WP4K@28221|Deltaproteobacteria,2YV49@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in the binding of tRNA to the ribosomes	rpsJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
SHD3_k127_2952984_5	448385.sce0843	2.432e-79	269.0	COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,42MPW@68525|delta/epsilon subdivisions,2WN96@28221|Deltaproteobacteria,2YW7S@29|Myxococcales	28221|Deltaproteobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
SHD3_k127_2952984_22	448385.sce0844	1.199e-31	127.0	COG0089@1|root,COG0089@2|Bacteria,1MZXX@1224|Proteobacteria,42V3Y@68525|delta/epsilon subdivisions,2WRMX@28221|Deltaproteobacteria,2Z0X0@29|Myxococcales	28221|Deltaproteobacteria	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
SHD3_k127_2952984_2	1192034.CAP_0435	7.547e-137	439.0	COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,42MBV@68525|delta/epsilon subdivisions,2WIRE@28221|Deltaproteobacteria,2YTYD@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
SHD3_k127_2952984_18	1192034.CAP_0434	2.884e-48	174.0	COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,42THY@68525|delta/epsilon subdivisions,2WQ0F@28221|Deltaproteobacteria,2YVJ3@29|Myxococcales	28221|Deltaproteobacteria	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
SHD3_k127_2952984_27	1453505.JASY01000021_gene29	1.968e-16	91.0	COG0457@1|root,COG2849@1|root,COG0457@2|Bacteria,COG2849@2|Bacteria,4NMDX@976|Bacteroidetes,1I51X@117743|Flavobacteriia,2NVG3@237|Flavobacterium	976|Bacteroidetes	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2,TPR_1,TPR_16,TPR_8
SHD3_k127_2952984_21	448385.sce7958	1.54e-39	155.0	COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,42TRE@68525|delta/epsilon subdivisions,2WQBH@28221|Deltaproteobacteria,2Z1JN@29|Myxococcales	28221|Deltaproteobacteria	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
SHD3_k127_2952984_3	448385.sce7957	1.422e-123	403.0	COG0092@1|root,COG0092@2|Bacteria,1MUAI@1224|Proteobacteria,42N5W@68525|delta/epsilon subdivisions,2WIU3@28221|Deltaproteobacteria,2YUEX@29|Myxococcales	28221|Deltaproteobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
SHD3_k127_2952984_11	1192034.CAP_1821	1.373e-59	208.0	COG0197@1|root,COG0197@2|Bacteria,1RA0Z@1224|Proteobacteria,42QW5@68525|delta/epsilon subdivisions,2WP71@28221|Deltaproteobacteria,2YV82@29|Myxococcales	28221|Deltaproteobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
SHD3_k127_2952984_31	448385.sce7955	3.838e-09	68.0	COG0255@1|root,COG0255@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
SHD3_k127_2952984_23	1254432.SCE1572_45675	6.875e-31	123.0	COG0186@1|root,COG0186@2|Bacteria,1MZIK@1224|Proteobacteria,42TNS@68525|delta/epsilon subdivisions,2WR6G@28221|Deltaproteobacteria,2Z0QF@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
SHD3_k127_2952984_12	439235.Dalk_1905	3.325e-55	195.0	COG0093@1|root,COG0093@2|Bacteria,1RCWZ@1224|Proteobacteria,42RHR@68525|delta/epsilon subdivisions,2WNEK@28221|Deltaproteobacteria,2MJSK@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
SHD3_k127_2952984_24	1401328.P856_136	3.879e-25	109.0	COG0198@1|root,COG0198@2|Bacteria,1MZQD@1224|Proteobacteria,2UC6Y@28211|Alphaproteobacteria,2JT9D@204441|Rhodospirillales	204441|Rhodospirillales	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
SHD3_k127_2952984_6	1192034.CAP_1826	1.025e-73	255.0	COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,42QS6@68525|delta/epsilon subdivisions,2WMPD@28221|Deltaproteobacteria,2YURE@29|Myxococcales	28221|Deltaproteobacteria	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
SHD3_k127_2952984_25	448385.sce7950	1.147e-23	100.0	COG0199@1|root,COG0199@2|Bacteria,1PDMJ@1224|Proteobacteria,42VCE@68525|delta/epsilon subdivisions,2WR7W@28221|Deltaproteobacteria,2YW33@29|Myxococcales	28221|Deltaproteobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
SHD3_k127_2952984_19	448385.sce7949	8.151e-47	171.0	COG0096@1|root,COG0096@2|Bacteria,1RDG3@1224|Proteobacteria,42SF6@68525|delta/epsilon subdivisions,2WPDP@28221|Deltaproteobacteria,2YVKK@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
SHD3_k127_2952984_10	448385.sce7948	6.767e-60	214.0	COG0097@1|root,COG0097@2|Bacteria,1R9YZ@1224|Proteobacteria,42NSE@68525|delta/epsilon subdivisions,2WN9B@28221|Deltaproteobacteria,2YV6Z@29|Myxococcales	28221|Deltaproteobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
SHD3_k127_2952984_16	448385.sce7947	2.59e-51	183.0	COG0256@1|root,COG0256@2|Bacteria,1RGY7@1224|Proteobacteria,42TIT@68525|delta/epsilon subdivisions,2WQ8U@28221|Deltaproteobacteria,2YVEW@29|Myxococcales	28221|Deltaproteobacteria	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
SHD3_k127_2952984_7	1192034.CAP_1830	2.246e-73	252.0	COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,42QX0@68525|delta/epsilon subdivisions,2WNBN@28221|Deltaproteobacteria,2Z01M@29|Myxococcales	28221|Deltaproteobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
SHD3_k127_2952984_26	1192034.CAP_1831	1.445e-16	87.0	COG1841@1|root,COG1841@2|Bacteria,1Q1P2@1224|Proteobacteria,437D4@68525|delta/epsilon subdivisions,2X2J6@28221|Deltaproteobacteria,2YW77@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein L30	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
SHD3_k127_2952984_20	448385.sce7944	2.008e-44	168.0	COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,42SRC@68525|delta/epsilon subdivisions,2WQQ4@28221|Deltaproteobacteria,2YVK2@29|Myxococcales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
SHD3_k127_2952984_0	1192034.CAP_1833	9.384e-192	609.0	COG0201@1|root,COG0201@2|Bacteria,1MVU7@1224|Proteobacteria,42MGM@68525|delta/epsilon subdivisions,2WIZ7@28221|Deltaproteobacteria,2YU46@29|Myxococcales	28221|Deltaproteobacteria	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
SHD3_k127_2952984_8	1254432.SCE1572_45620	1.295e-70	245.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,42M8E@68525|delta/epsilon subdivisions,2WJH0@28221|Deltaproteobacteria,2YV4U@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
SHD3_k127_2952984_30	1033737.CAEV01000063_gene2725	4.122e-10	62.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,36KM7@31979|Clostridiaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SHD3_k127_2952984_28	1254432.SCE1572_45610	8.832e-15	74.0	COG0257@1|root,COG0257@2|Bacteria,1NGEI@1224|Proteobacteria,42WXD@68525|delta/epsilon subdivisions,2WSYK@28221|Deltaproteobacteria,2YW0P@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL36 family	rpmJ	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
SHD3_k127_2952984_14	1254432.SCE1572_45605	1.564e-53	191.0	COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,42RE3@68525|delta/epsilon subdivisions,2WPD5@28221|Deltaproteobacteria,2YVHF@29|Myxococcales	28221|Deltaproteobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
SHD3_k127_2952984_9	1192034.CAP_1837	2.259e-62	216.0	COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,42R43@68525|delta/epsilon subdivisions,2WPH1@28221|Deltaproteobacteria,2YVAP@29|Myxococcales	28221|Deltaproteobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
SHD3_k127_2952984_4	448385.sce7937	4.342e-92	306.0	COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,42M5X@68525|delta/epsilon subdivisions,2WJGN@28221|Deltaproteobacteria,2YU1D@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
SHD3_k127_2952984_1	1254432.SCE1572_45590	5.995e-178	563.0	COG0202@1|root,COG0202@2|Bacteria,1MU75@1224|Proteobacteria,42MIX@68525|delta/epsilon subdivisions,2WJ5K@28221|Deltaproteobacteria,2YXN1@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
SHD3_k127_2952984_17	448385.sce7935	4.168e-50	182.0	COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,42SBD@68525|delta/epsilon subdivisions,2WP9P@28221|Deltaproteobacteria,2YVU9@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein L17	rplQ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
SHD3_k127_2952984_15	1121406.JAEX01000002_gene1127	2.675e-52	194.0	COG0500@1|root,COG2226@2|Bacteria,1RFDN@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
SHD3_k127_2970323_1	1192034.CAP_5778	2.749e-87	310.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_2970323_3	1192034.CAP_5779	3.26e-16	86.0	COG1314@1|root,COG1314@2|Bacteria,1NJ1D@1224|Proteobacteria,42TKW@68525|delta/epsilon subdivisions,2WRA3@28221|Deltaproteobacteria,2YVR1@29|Myxococcales	28221|Deltaproteobacteria	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
SHD3_k127_2970323_2	1192034.CAP_5781	1.293e-79	280.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,2YTW5@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SHD3_k127_2970323_0	930171.Asphe3_31610	1.593e-93	329.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,CHB_HEX_C_1,Cellulase,F5_F8_type_C
SHD3_k127_2972078_3	1500301.JQMF01000002_gene699	5.323e-24	115.0	COG5555@1|root,COG5555@2|Bacteria,1NBMC@1224|Proteobacteria,2UPAC@28211|Alphaproteobacteria,4BC6B@82115|Rhizobiaceae	28211|Alphaproteobacteria	N	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SHD3_k127_2972078_1	1192034.CAP_5683	8.078e-62	228.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,43CTF@68525|delta/epsilon subdivisions,2X80Z@28221|Deltaproteobacteria,2Z067@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_2972078_0	448385.sce4543	1.118e-131	438.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,43ARV@68525|delta/epsilon subdivisions,2X65Y@28221|Deltaproteobacteria,2Z39J@29|Myxococcales	448385.sce4543|-	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SHD3_k127_2972078_4	290397.Adeh_0078	2.135e-06	52.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2978938_2	243090.RB3466	4.59e-47	171.0	COG0187@1|root,COG0187@2|Bacteria,2IWXP@203682|Planctomycetes	203682|Planctomycetes	L	COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit	-	-	5.99.1.3	ko:K02470,ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SHD3_k127_2978938_1	595460.RRSWK_04301	2.536e-300	940.0	COG0188@1|root,COG0188@2|Bacteria,2IXMT@203682|Planctomycetes	203682|Planctomycetes	L	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SHD3_k127_2978938_0	1192034.CAP_3405	0.0	1037.0	COG4775@1|root,COG4775@2|Bacteria,1MU0D@1224|Proteobacteria,42MMA@68525|delta/epsilon subdivisions,2WIZB@28221|Deltaproteobacteria,2YUN3@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamA	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
SHD3_k127_2985268_9	251221.35214326	4.086e-25	107.0	COG0693@1|root,COG0693@2|Bacteria,1G2VP@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM intracellular protease, PfpI family	-	-	3.5.1.124	ko:K03152,ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI,DUF2383
SHD3_k127_2985268_1	1192034.CAP_2417	2.394e-215	697.0	COG2937@1|root,COG2937@2|Bacteria,1MWZ6@1224|Proteobacteria,42MN4@68525|delta/epsilon subdivisions,2WJJ5@28221|Deltaproteobacteria,2YW2Y@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the GPAT DAPAT family	plsB	-	2.3.1.15	ko:K00631	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SHD3_k127_2985268_6	1192034.CAP_2416	5.824e-79	272.0	COG3770@1|root,COG3770@2|Bacteria,1QA7G@1224|Proteobacteria,43DYC@68525|delta/epsilon subdivisions,2WZ6W@28221|Deltaproteobacteria,2Z1GB@29|Myxococcales	28221|Deltaproteobacteria	M	Penicillin-insensitive murein endopeptidase	-	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M74
SHD3_k127_2985268_3	448385.sce9358	3.531e-102	340.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42RUT@68525|delta/epsilon subdivisions,2X9ZW@28221|Deltaproteobacteria,2Z1HJ@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SHD3_k127_2985268_10	1211814.CAPG01000022_gene835	1.868e-07	61.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,4HB4C@91061|Bacilli,1ZFF1@1386|Bacillus	91061|Bacilli	E	YoaP-like	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
SHD3_k127_2985268_5	448385.sce0734	1.186e-81	291.0	COG1032@1|root,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,43AF4@68525|delta/epsilon subdivisions,2X5UV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_2985268_12	69319.XP_008559522.1	0.00062	52.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,46JI8@7399|Hymenoptera	33208|Metazoa	T	Low-density lipoprotein receptor domain class A	-	-	-	-	-	-	-	-	-	-	-	-	EGF_3,EGF_CA,NIDO,Zona_pellucida,hEGF
SHD3_k127_2985268_0	1279038.KB907340_gene1566	5.345e-309	955.0	COG1274@1|root,COG1274@2|Bacteria,1MX3C@1224|Proteobacteria,2TUPJ@28211|Alphaproteobacteria,2JRME@204441|Rhodospirillales	204441|Rhodospirillales	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
SHD3_k127_2985268_4	526227.Mesil_0175	4.77e-86	303.0	COG0009@1|root,COG0009@2|Bacteria,1WJN4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	Sua5 YciO YrdC YwlC family protein	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
SHD3_k127_2985268_2	1192034.CAP_5632	1.655e-119	407.0	COG0745@1|root,COG3437@1|root,COG3667@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG3667@2|Bacteria,1QXU5@1224|Proteobacteria,43C6N@68525|delta/epsilon subdivisions,2X7GW@28221|Deltaproteobacteria,2YUUA@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HD_5,Response_reg,T2SSE_N
SHD3_k127_2987468_5	1254432.SCE1572_02315	8.143e-10	70.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_2987468_3	1254432.SCE1572_02320	8.565e-39	154.0	COG1595@1|root,COG1595@2|Bacteria,1QR72@1224|Proteobacteria,43E0Y@68525|delta/epsilon subdivisions,2WZDM@28221|Deltaproteobacteria,2Z1WN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_2987468_4	1254432.SCE1572_02325	1.673e-11	73.0	2DK48@1|root,308EE@2|Bacteria,1QSG3@1224|Proteobacteria,4357G@68525|delta/epsilon subdivisions,2WZIH@28221|Deltaproteobacteria,2Z27V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2987468_1	448385.sce5364	7.424e-65	231.0	28VPU@1|root,2ZHRS@2|Bacteria,1R7QU@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_2987468_2	1254432.SCE1572_10990	1.784e-64	233.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SHD3_k127_2987468_0	452637.Oter_0715	5.461e-217	688.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SF8@74201|Verrucomicrobia,3K8ZC@414999|Opitutae	414999|Opitutae	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.21,1.2.1.22,1.2.1.88,1.5.5.2	ko:K07248,ko:K13821	ko00250,ko00330,ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00250,map00330,map00620,map00630,map01100,map01110,map01120,map01130	-	R00203,R00245,R00707,R00708,R01253,R01333,R01446,R04444,R04445,R05051	RC00080,RC00083,RC00104,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh
SHD3_k127_2987676_5	596151.DesfrDRAFT_2790	5.382e-19	100.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2M99V@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Spermine/spermidine synthase domain	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_2987676_1	589865.DaAHT2_0592	8.186e-87	305.0	COG2267@1|root,COG2267@2|Bacteria,1R80M@1224|Proteobacteria,43ATD@68525|delta/epsilon subdivisions	1224|Proteobacteria	M	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
SHD3_k127_2987676_4	448385.sce1644	3.441e-37	153.0	COG1191@1|root,COG1191@2|Bacteria,1Q2IP@1224|Proteobacteria,4385G@68525|delta/epsilon subdivisions,2X9Y3@28221|Deltaproteobacteria,2YVUY@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
SHD3_k127_2987676_3	1192034.CAP_4563	3.607e-51	189.0	COG1266@1|root,COG1266@2|Bacteria,1RI59@1224|Proteobacteria,433F0@68525|delta/epsilon subdivisions,2WYHI@28221|Deltaproteobacteria,2Z276@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SHD3_k127_2987676_0	448385.sce2546	3.894e-218	689.0	COG2203@1|root,COG2204@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2204@2|Bacteria,COG2206@2|Bacteria,1RAQS@1224|Proteobacteria,42MEJ@68525|delta/epsilon subdivisions,2X71A@28221|Deltaproteobacteria,2YUZY@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GAF_3,HD,Response_reg
SHD3_k127_2987676_2	1254432.SCE1572_15250	6.501e-75	261.0	COG0321@1|root,COG0321@2|Bacteria,1MU6A@1224|Proteobacteria,42RIC@68525|delta/epsilon subdivisions,2WPRF@28221|Deltaproteobacteria,2YVCE@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate	lipB	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,NUDIX
SHD3_k127_3000630_3	1230343.CANP01000005_gene394	3.364e-74	260.0	COG4221@1|root,COG4221@2|Bacteria,1QY9P@1224|Proteobacteria,1T3MV@1236|Gammaproteobacteria,1JFU6@118969|Legionellales	118969|Legionellales	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_3000630_1	448385.sce7801	7.704e-194	619.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42P6D@68525|delta/epsilon subdivisions,2WM1P@28221|Deltaproteobacteria,2YUD4@29|Myxococcales	28221|Deltaproteobacteria	T	DNA-binding response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_3000630_6	1254432.SCE1572_07835	4.924e-25	121.0	COG2204@1|root,COG2204@2|Bacteria,1NABF@1224|Proteobacteria,43C0I@68525|delta/epsilon subdivisions,2X7B5@28221|Deltaproteobacteria,2YVMV@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_3000630_5	388051.AUFE01000016_gene5843	1.623e-41	168.0	COG0845@1|root,COG0845@2|Bacteria,1R4E4@1224|Proteobacteria,2VN9E@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SHD3_k127_3000630_0	330214.NIDE1804	2.593e-294	935.0	COG3696@1|root,COG3696@2|Bacteria,3J0ZR@40117|Nitrospirae	40117|Nitrospirae	P	AcrB/AcrD/AcrF family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SHD3_k127_3000630_7	330214.NIDE1802	7.776e-23	112.0	COG1538@1|root,COG1538@2|Bacteria,3J1F2@40117|Nitrospirae	40117|Nitrospirae	MU	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SHD3_k127_3000630_8	477641.MODMU_5157	0.0002214	49.0	2DDN7@1|root,2ZIN3@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4190
SHD3_k127_3000630_2	448385.sce5869	2.092e-99	332.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2Z07Q@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
SHD3_k127_3000630_4	1242864.D187_010372	2.02e-53	203.0	COG2202@1|root,COG5002@1|root,COG2202@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SHD3_k127_3000947_1	1385935.N836_01620	6.967e-94	314.0	COG0655@1|root,COG0655@2|Bacteria,1GB8R@1117|Cyanobacteria,1HDV7@1150|Oscillatoriales	1117|Cyanobacteria	S	Nadph-dependent fmn reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SHD3_k127_3000947_3	491952.Mar181_1355	8.983e-26	113.0	COG0702@1|root,COG0702@2|Bacteria,1RDKF@1224|Proteobacteria,1S0A1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SHD3_k127_3000947_4	316274.Haur_1598	5.941e-23	116.0	COG1361@1|root,COG3266@1|root,COG5624@1|root,COG1361@2|Bacteria,COG3266@2|Bacteria,COG5624@2|Bacteria,2G94N@200795|Chloroflexi,377N8@32061|Chloroflexia	200795|Chloroflexi	K	Conserved repeat domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3000947_2	391625.PPSIR1_27218	8.819e-31	141.0	COG2939@1|root,COG2939@2|Bacteria,1Q4XB@1224|Proteobacteria,4302Y@68525|delta/epsilon subdivisions,2WV8P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Serine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S10
SHD3_k127_3000947_0	448385.sce1832	1.171e-124	410.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,43836@68525|delta/epsilon subdivisions,2X3D4@28221|Deltaproteobacteria,2YVHE@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 30 family	srfJ	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C,RicinB_lectin_2
SHD3_k127_3004652_2	909663.KI867150_gene133	6.638e-117	399.0	COG1330@1|root,COG1330@2|Bacteria,1MWTI@1224|Proteobacteria,42N6G@68525|delta/epsilon subdivisions,2WJ4Q@28221|Deltaproteobacteria,2MQWD@213462|Syntrophobacterales	28221|Deltaproteobacteria	L	Exodeoxyribonuclease V, gamma subunit	recC	-	3.1.11.5	ko:K03583	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_V_gamma
SHD3_k127_3004652_1	448385.sce4539	9.504e-138	459.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YUMV@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3004652_5	448385.sce4538	2.064e-22	109.0	COG0457@1|root,COG0457@2|Bacteria,1Q2MT@1224|Proteobacteria,433UE@68525|delta/epsilon subdivisions,2X3I3@28221|Deltaproteobacteria,2YW6Y@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3004652_3	1192034.CAP_4316	3.209e-95	317.0	COG0500@1|root,COG2226@2|Bacteria,1RASQ@1224|Proteobacteria,42QTY@68525|delta/epsilon subdivisions,2WMN2@28221|Deltaproteobacteria,2YWX8@29|Myxococcales	28221|Deltaproteobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SHD3_k127_3004652_7	1192034.CAP_4343	1.252e-05	58.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_4343|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3004652_0	1121904.ARBP01000010_gene2316	1.117e-156	513.0	COG1167@1|root,COG1167@2|Bacteria	2|Bacteria	K	transaminase activity	aspT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
SHD3_k127_3004652_6	455632.SGR_6939	5.783e-07	57.0	COG1846@1|root,COG1846@2|Bacteria,2IKND@201174|Actinobacteria,41BJX@629295|Streptomyces griseus group	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
SHD3_k127_3004652_4	375286.mma_0021	3.498e-41	172.0	COG0845@1|root,COG0845@2|Bacteria,1NQZ0@1224|Proteobacteria,2VNHM@28216|Betaproteobacteria,474AW@75682|Oxalobacteraceae	28216|Betaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SHD3_k127_3004652_8	887062.HGR_07536	6.289e-05	46.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,2VHFI@28216|Betaproteobacteria,4AAY8@80864|Comamonadaceae	28216|Betaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	nolG	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SHD3_k127_300592_0	1283300.ATXB01000001_gene665	3.865e-169	543.0	COG0297@1|root,COG0297@2|Bacteria,1P7F2@1224|Proteobacteria,1RZVJ@1236|Gammaproteobacteria,1XG73@135618|Methylococcales	135618|Methylococcales	G	Starch synthase catalytic domain	-	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
SHD3_k127_300592_3	1254432.SCE1572_40455	6.955e-38	146.0	COG3450@1|root,COG3450@2|Bacteria,1N8CD@1224|Proteobacteria,431DE@68525|delta/epsilon subdivisions,2WW7R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Protein of unknown function (DUF861)	-	-	-	ko:K06995	-	-	-	-	ko00000	-	-	-	Cupin_3
SHD3_k127_300592_2	1499967.BAYZ01000026_gene1576	1.338e-41	165.0	COG0613@1|root,COG0613@2|Bacteria,2NR6H@2323|unclassified Bacteria	2|Bacteria	S	PHP domain protein	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP,PHP_C
SHD3_k127_300592_1	553385.JEMF01000025_gene141	3.413e-49	180.0	COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,1XJ7F@135619|Oceanospirillales	135619|Oceanospirillales	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SHD3_k127_3006385_0	1192034.CAP_7480	7.76e-177	563.0	COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,42KZ7@68525|delta/epsilon subdivisions,2WJP6@28221|Deltaproteobacteria,2YU49@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iAF987.Gmet_1487	GATase_6,SIS
SHD3_k127_3006385_1	404589.Anae109_3834	4.811e-111	374.0	COG1055@1|root,COG1055@2|Bacteria,1MXKG@1224|Proteobacteria,42PAX@68525|delta/epsilon subdivisions,2WKEP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
SHD3_k127_3006385_2	448385.sce7411	2.312e-101	349.0	COG0747@1|root,COG0747@2|Bacteria	2|Bacteria	E	dipeptide transport	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
SHD3_k127_3010355_1	1306174.JODP01000013_gene7765	1.068e-84	284.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SHD3_k127_3010355_5	1300345.LF41_148	1.749e-05	48.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,1RN5I@1236|Gammaproteobacteria,1X3SP@135614|Xanthomonadales	135614|Xanthomonadales	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SHD3_k127_3010355_4	42565.FP66_10530	3.789e-06	60.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,1RPI3@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	SPOR,Sel1
SHD3_k127_3010355_2	582515.KR51_00004800	1.134e-53	213.0	COG0705@1|root,COG0705@2|Bacteria,1G1Z3@1117|Cyanobacteria	1117|Cyanobacteria	S	PFAM Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
SHD3_k127_3010355_3	448385.sce4332	3.283e-48	189.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce4332|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3010355_0	448385.sce4512	9.604e-103	353.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3016359_0	1254432.SCE1572_39610	9.024e-225	707.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,43836@68525|delta/epsilon subdivisions,2X3D4@28221|Deltaproteobacteria,2YVHE@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 30 family	srfJ	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C,RicinB_lectin_2
SHD3_k127_3016359_4	397945.Aave_1288	1e-68	248.0	COG0463@1|root,COG0463@2|Bacteria,1P8G7@1224|Proteobacteria,2VTB4@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_3016359_5	448385.sce4876	2.05e-18	91.0	COG1848@1|root,COG1848@2|Bacteria,1RFYN@1224|Proteobacteria,43015@68525|delta/epsilon subdivisions,2WV6Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3016359_2	755731.Clo1100_2937	9.654e-103	365.0	COG1472@1|root,COG1472@2|Bacteria,1VSFU@1239|Firmicutes,25BFI@186801|Clostridia,36WFE@31979|Clostridiaceae	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_3016359_1	1254432.SCE1572_39610	1.458e-157	513.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,43836@68525|delta/epsilon subdivisions,2X3D4@28221|Deltaproteobacteria,2YVHE@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 30 family	srfJ	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C,RicinB_lectin_2
SHD3_k127_3016359_6	240292.Ava_1882	1.159e-12	81.0	COG3420@1|root,COG3420@2|Bacteria,1GR0V@1117|Cyanobacteria,1HTIB@1161|Nostocales	2|Bacteria	P	Right handed beta helix region	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Beta_helix,DUF1565,DUF4082,HemolysinCabind
SHD3_k127_3016359_3	1192034.CAP_5588	2.818e-75	277.0	COG1807@1|root,COG1807@2|Bacteria,1N5QJ@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_3019565_2	1144275.COCOR_05769	6.147e-58	209.0	COG0531@1|root,COG0531@2|Bacteria,1MUA2@1224|Proteobacteria,42T8N@68525|delta/epsilon subdivisions,2WZ91@28221|Deltaproteobacteria,2Z1M2@29|Myxococcales	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SHD3_k127_3019565_0	1254432.SCE1572_22720	1.762e-123	410.0	COG0515@1|root,COG0515@2|Bacteria	1254432.SCE1572_22720|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SHD3_k127_3019565_3	1254432.SCE1572_22725	6.439e-54	200.0	COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,2YVT7@29|Myxococcales	28221|Deltaproteobacteria	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
SHD3_k127_3019565_1	1192034.CAP_6944	1.382e-78	269.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42M4I@68525|delta/epsilon subdivisions,2WJHM@28221|Deltaproteobacteria,2YY9M@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SHD3_k127_3023130_2	1380386.JIAW01000014_gene2814	6.275e-25	104.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,233CA@1762|Mycobacteriaceae	201174|Actinobacteria	P	thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate	atsD	GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SHD3_k127_3023130_1	118173.KB235914_gene1097	2.499e-61	226.0	COG0683@1|root,COG0683@2|Bacteria,1G4Y1@1117|Cyanobacteria	1117|Cyanobacteria	E	leucine binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3023130_3	1121875.KB907547_gene2992	1.138e-13	78.0	COG2149@1|root,COG2149@2|Bacteria,4NZMM@976|Bacteroidetes	976|Bacteroidetes	S	Domain of unknown function (DUF202)	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
SHD3_k127_3023130_0	304371.MCP_2346	4.444e-73	254.0	COG0641@1|root,arCOG00945@2157|Archaea,2Y0F7@28890|Euryarchaeota,2NAGD@224756|Methanomicrobia	224756|Methanomicrobia	K	SEC-C motif	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
SHD3_k127_3051539_1	583355.Caka_0958	5.27e-90	302.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
SHD3_k127_3051539_0	404589.Anae109_0529	4.694e-129	453.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria,2YZ0R@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SHD3_k127_3051539_3	247490.KSU1_D0360	1.249e-44	188.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SHD3_k127_3051539_2	552811.Dehly_1197	6.636e-64	233.0	COG4826@1|root,COG4826@2|Bacteria,2GBWN@200795|Chloroflexi,34D50@301297|Dehalococcoidia	301297|Dehalococcoidia	M	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SHD3_k127_3054920_0	1254432.SCE1572_05925	5.42e-218	680.0	COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,42MWZ@68525|delta/epsilon subdivisions,2WJ2B@28221|Deltaproteobacteria,2YX6I@29|Myxococcales	28221|Deltaproteobacteria	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SHD3_k127_3054920_5	1192034.CAP_8437	4.763e-73	263.0	COG1729@1|root,COG1729@2|Bacteria,1R0BI@1224|Proteobacteria,43CTU@68525|delta/epsilon subdivisions,2X81F@28221|Deltaproteobacteria,2Z3J8@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3054920_7	448385.sce0784	9.677e-59	215.0	COG0220@1|root,COG0220@2|Bacteria,1MUWJ@1224|Proteobacteria,42M78@68525|delta/epsilon subdivisions,2WRKW@28221|Deltaproteobacteria,2YVUK@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
SHD3_k127_3054920_2	448385.sce0783	5.117e-140	469.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3054920_11	391625.PPSIR1_06648	1.401e-05	57.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3054920_4	1254432.SCE1572_04515	7.739e-95	326.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria	1224|Proteobacteria	C	Aldo Keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SHD3_k127_3054920_3	1192034.CAP_8449	1.257e-99	348.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,DUF4145,Pentapeptide,RDD
SHD3_k127_3054920_1	502025.Hoch_5108	1.703e-186	604.0	COG1716@1|root,COG2203@1|root,COG3829@1|root,COG1716@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6YI@28221|Deltaproteobacteria,2YZGR@29|Myxococcales	28221|Deltaproteobacteria	KT	Sigma-54 interaction domain	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_3054920_6	391625.PPSIR1_16065	3.212e-59	216.0	COG3221@1|root,COG3221@2|Bacteria	2|Bacteria	P	organic phosphonate transport	CP_0018	-	-	ko:K02044	ko02010,map02010	M00223	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.9	-	-	Phosphonate-bd
SHD3_k127_3066609_1	1206726.BAFV01000056_gene4121	1.012e-163	527.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4FTXY@85025|Nocardiaceae	201174|Actinobacteria	G	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	GO:0000271,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901576	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
SHD3_k127_3066609_4	1254432.SCE1572_25295	7.288e-57	214.0	COG0392@1|root,COG0392@2|Bacteria,1RCGI@1224|Proteobacteria,42RDB@68525|delta/epsilon subdivisions,2WMU8@28221|Deltaproteobacteria,2Z17J@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SHD3_k127_3066609_3	391625.PPSIR1_16910	6.115e-103	351.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,2YV19@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SHD3_k127_3066609_2	1254432.SCE1572_07045	9.638e-120	398.0	COG1451@1|root,COG1451@2|Bacteria,1RDZ9@1224|Proteobacteria,42SB4@68525|delta/epsilon subdivisions,2WNVN@28221|Deltaproteobacteria,2YYVM@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2786,SprT-like
SHD3_k127_3066609_0	187303.BN69_2262	0.0	1268.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,1MV6G@1224|Proteobacteria,2TQTG@28211|Alphaproteobacteria,36XTN@31993|Methylocystaceae	28211|Alphaproteobacteria	E	B12 binding domain	metH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SHD3_k127_3071095_9	42345.XP_008807062.1	1.066e-07	62.0	28Q1Z@1|root,2QWQN@2759|Eukaryota,37QJS@33090|Viridiplantae,3GG93@35493|Streptophyta,3MAVT@4447|Liliopsida	35493|Streptophyta	S	Hydrophobic seed protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrophob_seed
SHD3_k127_3071095_0	391625.PPSIR1_40645	2.068e-122	411.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2YTVT@29|Myxococcales	28221|Deltaproteobacteria	C	Fe-S oxidoreductases	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_3071095_7	391625.PPSIR1_30549	9.962e-34	142.0	COG0791@1|root,COG0791@2|Bacteria	2|Bacteria	M	cysteine-type peptidase activity	-	-	-	ko:K21471,ko:K21473,ko:K21687	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	GH23	-	LysM,NLPC_P60,SH3_3,SLT,Transglycosylas
SHD3_k127_3071095_4	391625.PPSIR1_02166	2.221e-88	309.0	COG5297@1|root,COG5297@2|Bacteria,1R8MG@1224|Proteobacteria,434I9@68525|delta/epsilon subdivisions,2WYVI@28221|Deltaproteobacteria,2Z0QV@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase family 6	celA	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,Glyco_hydro_6
SHD3_k127_3071095_6	1254432.SCE1572_13630	2.333e-37	154.0	COG0517@1|root,COG0517@2|Bacteria,1PXJK@1224|Proteobacteria,434MB@68525|delta/epsilon subdivisions,2X8XT@28221|Deltaproteobacteria,2Z0YD@29|Myxococcales	28221|Deltaproteobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
SHD3_k127_3071095_11	448385.sce8069	6.755e-05	56.0	COG3170@1|root,COG3170@2|Bacteria,1QX3V@1224|Proteobacteria,43BWB@68525|delta/epsilon subdivisions,2X773@28221|Deltaproteobacteria,2YVT2@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SHD3_k127_3071095_1	290397.Adeh_2778	8.746e-102	353.0	COG5434@1|root,COG5434@2|Bacteria,1QYGC@1224|Proteobacteria,43CCG@68525|delta/epsilon subdivisions,2WR1K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Pectate_lyase_3
SHD3_k127_3071095_2	1205680.CAKO01000016_gene143	1.106e-93	316.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2U16Z@28211|Alphaproteobacteria,2JRZM@204441|Rhodospirillales	204441|Rhodospirillales	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
SHD3_k127_3071095_5	595460.RRSWK_01149	3.276e-55	204.0	COG0631@1|root,COG0631@2|Bacteria,2IZVG@203682|Planctomycetes	203682|Planctomycetes	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SHD3_k127_3071095_3	448385.sce4512	2.282e-93	323.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3071095_10	164757.Mjls_5052	7.625e-07	51.0	COG0189@1|root,COG0189@2|Bacteria,2GN0U@201174|Actinobacteria,2356T@1762|Mycobacteriaceae	201174|Actinobacteria	HJK	acetyltransferase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acylphosphatase,CPSase_L_D2,RimK
SHD3_k127_3075420_2	472759.Nhal_3638	1.017e-10	64.0	2DTSM@1|root,33MH2@2|Bacteria	2|Bacteria	S	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SHD3_k127_3075420_3	671143.DAMO_2748	1.045e-09	67.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_3075420_0	223926.28809294	9.325e-33	146.0	COG1361@1|root,COG5295@1|root,COG1361@2|Bacteria,COG5295@2|Bacteria,1MUQC@1224|Proteobacteria,1T39T@1236|Gammaproteobacteria,1XUYV@135623|Vibrionales	135623|Vibrionales	M	Gametolysin peptidase M11	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc,Peptidase_M11
SHD3_k127_3075420_1	1123508.JH636444_gene5205	3.634e-21	106.0	COG4099@1|root,COG4099@2|Bacteria,2IZFN@203682|Planctomycetes	203682|Planctomycetes	S	Phospholipase/Carboxylesterase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S9
SHD3_k127_3078128_3	378806.STAUR_0754	9.628e-13	78.0	2EIZM@1|root,33CQT@2|Bacteria,1P1YR@1224|Proteobacteria,439UY@68525|delta/epsilon subdivisions,2X58M@28221|Deltaproteobacteria,2Z09N@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3078128_1	448385.sce5073	5.695e-90	307.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,42MP1@68525|delta/epsilon subdivisions,2WJPD@28221|Deltaproteobacteria,2YURD@29|Myxococcales	28221|Deltaproteobacteria	K	Two component transcriptional regulator, winged helix family	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_3078128_2	448385.sce6967	2.337e-30	127.0	COG2204@1|root,COG2204@2|Bacteria,1NABF@1224|Proteobacteria,43C0I@68525|delta/epsilon subdivisions,2X7B5@28221|Deltaproteobacteria,2Z3KD@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_3078128_0	502025.Hoch_4790	3.129e-109	364.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YYCB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_3081738_3	502025.Hoch_2910	6.596e-19	87.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2YV8H@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SHD3_k127_3081738_1	1242864.D187_008146	1.256e-84	291.0	COG1621@1|root,COG1621@2|Bacteria,1R2XX@1224|Proteobacteria,43DHW@68525|delta/epsilon subdivisions,2X8PM@28221|Deltaproteobacteria,2Z10P@29|Myxococcales	2|Bacteria	G	Alpha-L-arabinofuranosidase B (ABFB) domain	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	AbfB,Glyco_hydro_32C,Glyco_hydro_32N,Glyco_hydro_43
SHD3_k127_3081738_0	1121926.AXWO01000015_gene4292	7.546e-100	338.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,Big_4,Dockerin_1,Glyco_hydro_43,Laminin_G_3
SHD3_k127_3081738_2	1120949.KB903314_gene392	7.252e-21	97.0	COG1073@1|root,COG4733@1|root,COG1073@2|Bacteria,COG4733@2|Bacteria,2GK1U@201174|Actinobacteria,4DBS1@85008|Micromonosporales	201174|Actinobacteria	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_3081836_6	1382306.JNIM01000001_gene1471	1.083e-49	201.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SHD3_k127_3081836_1	1121918.ARWE01000001_gene3102	5.678e-163	523.0	COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42PNI@68525|delta/epsilon subdivisions,2WJNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM natural resistance-associated macrophage protein	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp,Usp
SHD3_k127_3081836_4	1254432.SCE1572_00050	1.26e-72	259.0	COG0564@1|root,COG0564@2|Bacteria,1MVJ5@1224|Proteobacteria,42PI3@68525|delta/epsilon subdivisions,2WJN3@28221|Deltaproteobacteria,2YZZD@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RluA family	-	-	5.4.99.23,5.4.99.28,5.4.99.29	ko:K06177,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03016	-	-	-	PseudoU_synth_2
SHD3_k127_3081836_3	685778.AORL01000021_gene904	3.321e-74	272.0	COG1032@1|root,COG1032@2|Bacteria,1NAY8@1224|Proteobacteria,2TV1I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_3081836_2	448385.sce6264	1.916e-86	304.0	COG4775@1|root,COG4775@2|Bacteria	2|Bacteria	M	membrane organization	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,CarboxypepD_reg,Laminin_G_3,POTRA
SHD3_k127_3081836_7	1397528.Q671_09110	2.148e-06	60.0	COG0265@1|root,COG3016@1|root,COG0265@2|Bacteria,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,1RPWZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Iron-regulated protein	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
SHD3_k127_3081836_5	1192034.CAP_5247	4.693e-57	202.0	COG3973@1|root,COG3973@2|Bacteria,1P638@1224|Proteobacteria,42MXR@68525|delta/epsilon subdivisions,2WK1Z@28221|Deltaproteobacteria,2Z32G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD_C_2
SHD3_k127_3082259_1	1121346.KB899835_gene949	1.392e-273	853.0	COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,4HB1E@91061|Bacilli,26SW8@186822|Paenibacillaceae	91061|Bacilli	G	the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
SHD3_k127_3082259_3	886293.Sinac_4875	5.194e-54	202.0	COG2755@1|root,COG2755@2|Bacteria,2IZ2H@203682|Planctomycetes	203682|Planctomycetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_3082259_2	316067.Geob_3650	7.011e-218	695.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SHD3_k127_3082259_4	1121403.AUCV01000021_gene3592	3.2e-27	122.0	2EBU8@1|root,335TU@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
SHD3_k127_3082259_0	903818.KI912268_gene1451	0.0	1110.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SHD3_k127_3082259_5	1192034.CAP_0620	1.817e-06	60.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,NHL
SHD3_k127_3083907_11	1254432.SCE1572_45725	3.507e-30	126.0	COG1702@1|root,COG1702@2|Bacteria,1MVDV@1224|Proteobacteria,42N58@68525|delta/epsilon subdivisions,2WIQS@28221|Deltaproteobacteria,2YTWI@29|Myxococcales	28221|Deltaproteobacteria	T	PhoH-like protein	phoH2	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
SHD3_k127_3083907_2	1254432.SCE1572_45735	2.128e-112	376.0	COG0768@1|root,COG0768@2|Bacteria,1R7A0@1224|Proteobacteria,42MJC@68525|delta/epsilon subdivisions,2WJZ2@28221|Deltaproteobacteria,2YV14@29|Myxococcales	28221|Deltaproteobacteria	M	Cell division protein FtsI penicillin-binding protein 2	pbp4	-	-	-	-	-	-	-	-	-	-	-	Transpeptidase
SHD3_k127_3083907_0	1192034.CAP_1802	1e-273	876.0	COG0823@1|root,COG4775@1|root,COG0823@2|Bacteria,COG4775@2|Bacteria,1R8QH@1224|Proteobacteria,42T02@68525|delta/epsilon subdivisions,2WPNU@28221|Deltaproteobacteria,2YUP3@29|Myxococcales	28221|Deltaproteobacteria	MU	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,PD40
SHD3_k127_3083907_7	448385.sce7970	5.209e-53	200.0	COG3215@1|root,COG3215@2|Bacteria,1Q3B9@1224|Proteobacteria,4392F@68525|delta/epsilon subdivisions,2X485@28221|Deltaproteobacteria,2YYGF@29|Myxococcales	28221|Deltaproteobacteria	MNU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SHD3_k127_3083907_5	1254432.SCE1572_45765	7.211e-74	260.0	COG0223@1|root,COG0223@2|Bacteria,1PF16@1224|Proteobacteria,42RYZ@68525|delta/epsilon subdivisions	1224|Proteobacteria	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_C,Formyl_trans_N
SHD3_k127_3083907_3	448385.sce7972	8.943e-101	334.0	COG2884@1|root,COG2884@2|Bacteria,1MVQ4@1224|Proteobacteria,42MAM@68525|delta/epsilon subdivisions,2WK4Y@28221|Deltaproteobacteria,2YV0E@29|Myxococcales	28221|Deltaproteobacteria	D	ABC transporter	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
SHD3_k127_3083907_4	1254432.SCE1572_45775	4.895e-81	278.0	COG2177@1|root,COG2177@2|Bacteria,1MU65@1224|Proteobacteria,43BBA@68525|delta/epsilon subdivisions,2X6QG@28221|Deltaproteobacteria,2YVCX@29|Myxococcales	28221|Deltaproteobacteria	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
SHD3_k127_3083907_6	1254432.SCE1572_45780	3.482e-68	252.0	COG4942@1|root,COG4942@2|Bacteria,1MY3E@1224|Proteobacteria,42N32@68525|delta/epsilon subdivisions,2WKBN@28221|Deltaproteobacteria,2YVR8@29|Myxococcales	28221|Deltaproteobacteria	D	Peptidase family M23	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3
SHD3_k127_3083907_8	448385.sce7908	4.026e-39	160.0	COG0564@1|root,COG0564@2|Bacteria	2|Bacteria	J	pseudouridine synthase activity	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SHD3_k127_3083907_1	1192034.CAP_8363	2.773e-131	435.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439KJ@68525|delta/epsilon subdivisions,2X4XC@28221|Deltaproteobacteria,2Z096@29|Myxococcales	28221|Deltaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3084094_6	1121403.AUCV01000025_gene2298	5.493e-38	148.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42R36@68525|delta/epsilon subdivisions,2WU0Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	frzCD	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_4,PAS_9,dCache_1,sCache_3_2,sCache_3_3
SHD3_k127_3084094_7	622637.KE124774_gene725	5.403e-33	140.0	COG0835@1|root,COG0835@2|Bacteria,1RD1W@1224|Proteobacteria,2VFAW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SHD3_k127_3084094_0	338963.Pcar_1200	1.517e-108	363.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria,43S6W@69541|Desulfuromonadales	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	cheB34H	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SHD3_k127_3084094_5	521010.BbiDN127_0040	4.592e-38	154.0	COG1352@1|root,COG1352@2|Bacteria,2J7GX@203691|Spirochaetes	203691|Spirochaetes	NT	CheR methyltransferase, SAM binding domain	cheR-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SHD3_k127_3084094_1	240015.ACP_0962	2.048e-105	362.0	COG0643@1|root,COG0643@2|Bacteria,3Y3WE@57723|Acidobacteria,2JMFQ@204432|Acidobacteriia	204432|Acidobacteriia	NT	Signal transducing histidine kinase, homodimeric domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SHD3_k127_3084094_2	1192034.CAP_8756	1.29e-87	295.0	COG3647@1|root,COG3647@2|Bacteria,1N7NB@1224|Proteobacteria,42SI3@68525|delta/epsilon subdivisions,2WPVX@28221|Deltaproteobacteria,2YXH0@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2238)	-	-	-	ko:K08984	-	-	-	-	ko00000	-	-	-	DUF2238
SHD3_k127_3084094_4	357808.RoseRS_0421	2.968e-43	175.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_3084094_3	398512.JQKC01000006_gene743	3.583e-59	224.0	COG2006@1|root,COG2133@1|root,COG2006@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3084094_10	926569.ANT_18750	1.563e-12	70.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,Cellulase
SHD3_k127_3084094_9	880073.Calab_3094	4.221e-19	94.0	COG2730@1|root,COG2730@2|Bacteria,2NPWE@2323|unclassified Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,Cellulase
SHD3_k127_3086149_15	1123059.KB823011_gene915	5.855e-41	162.0	COG0548@1|root,COG0548@2|Bacteria,1MU17@1224|Proteobacteria,2TQQS@28211|Alphaproteobacteria,43YAH@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	NAT, N-acetyltransferase, of N-acetylglutamate synthase	-	-	2.3.1.1,2.7.2.8	ko:K22478	ko00220,ko01210,ko01230,map00220,map01210,map01230	M00028,M00845	R00259,R02649	RC00002,RC00004,RC00043,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,NAT
SHD3_k127_3086149_13	652103.Rpdx1_1759	2.259e-46	181.0	2DC2D@1|root,2ZCMG@2|Bacteria,1R8RP@1224|Proteobacteria,2U2PD@28211|Alphaproteobacteria,3JX6K@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Protein of unknown function (DUF3829)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3829
SHD3_k127_3086149_6	1192034.CAP_4337	6.749e-98	333.0	COG3325@1|root,COG3325@2|Bacteria,1RDYE@1224|Proteobacteria,438K8@68525|delta/epsilon subdivisions,2X3US@28221|Deltaproteobacteria,2YX66@29|Myxococcales	28221|Deltaproteobacteria	G	Glyco_18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,fn3
SHD3_k127_3086149_5	448385.sce0363	2.21e-114	388.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_3086149_16	509635.N824_20700	5.159e-40	158.0	COG2259@1|root,COG2259@2|Bacteria,4NYPC@976|Bacteroidetes,1IZT9@117747|Sphingobacteriia	976|Bacteroidetes	S	SURF4 family	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX,SURF4
SHD3_k127_3086149_0	1254432.SCE1572_37260	6.088e-287	902.0	COG4796@1|root,COG4796@2|Bacteria,1QTT6@1224|Proteobacteria,42MKN@68525|delta/epsilon subdivisions,2WJV6@28221|Deltaproteobacteria,2YTV4@29|Myxococcales	28221|Deltaproteobacteria	U	type IV pilus secretin PilQ	pilQ	-	-	ko:K02666	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	AMIN,STN,Secretin,Secretin_N
SHD3_k127_3086149_17	448385.sce6185	3.069e-39	160.0	COG3168@1|root,COG3168@2|Bacteria	2|Bacteria	NU	Pilus assembly protein, PilP	pilP	-	-	ko:K02665	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilP
SHD3_k127_3086149_14	448385.sce6186	4.442e-46	175.0	COG3167@1|root,COG3167@2|Bacteria,1RBGW@1224|Proteobacteria,42S1V@68525|delta/epsilon subdivisions,2WNDR@28221|Deltaproteobacteria,2YVZQ@29|Myxococcales	28221|Deltaproteobacteria	NU	Pilus assembly protein, PilO	pilO	-	-	ko:K02664	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilO
SHD3_k127_3086149_9	448385.sce6187	2.397e-64	228.0	COG3166@1|root,COG3166@2|Bacteria,1Q1I0@1224|Proteobacteria,42W65@68525|delta/epsilon subdivisions,2WS79@28221|Deltaproteobacteria,2Z2I6@29|Myxococcales	28221|Deltaproteobacteria	NU	Fimbrial assembly protein (PilN)	pilN	-	-	ko:K02663	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilN
SHD3_k127_3086149_1	1192034.CAP_3050	2.205e-151	487.0	COG4972@1|root,COG4972@2|Bacteria,1MX8P@1224|Proteobacteria,42M36@68525|delta/epsilon subdivisions,2WJFJ@28221|Deltaproteobacteria,2YUJQ@29|Myxococcales	28221|Deltaproteobacteria	NU	pilus assembly protein	pilM	-	-	ko:K02662	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	PilM_2
SHD3_k127_3086149_11	1254432.SCE1572_37285	1.13e-47	186.0	COG1388@1|root,COG3108@1|root,COG1388@2|Bacteria,COG3108@2|Bacteria,1QABK@1224|Proteobacteria,434YH@68525|delta/epsilon subdivisions,2WZ9D@28221|Deltaproteobacteria,2Z1MT@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial protein of unknown function (DUF882)	-	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M15_2
SHD3_k127_3086149_4	1254432.SCE1572_43080	2.958e-131	432.0	COG3014@1|root,COG3014@2|Bacteria,1PD4S@1224|Proteobacteria,42V8Q@68525|delta/epsilon subdivisions,2WRSG@28221|Deltaproteobacteria,2YW0X@29|Myxococcales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09859	-	-	-	-	ko00000	-	-	-	-
SHD3_k127_3086149_10	1254432.SCE1572_43075	7.425e-56	203.0	COG3417@1|root,COG3417@2|Bacteria,1RA6V@1224|Proteobacteria,42UKY@68525|delta/epsilon subdivisions,2WR6E@28221|Deltaproteobacteria,2YW6R@29|Myxococcales	28221|Deltaproteobacteria	M	Collagen-binding surface adhesin SpaP (antigen I II family)	-	-	-	ko:K07337	-	-	-	-	ko00000	-	-	-	LpoB
SHD3_k127_3086149_18	469383.Cwoe_4044	1.342e-27	125.0	COG0673@1|root,COG0673@2|Bacteria,2IEY3@201174|Actinobacteria,4CTIF@84995|Rubrobacteria	84995|Rubrobacteria	S	PFAM oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SHD3_k127_3086149_24	246437.XP_006162321.1	0.0002586	47.0	COG5028@1|root,KOG1985@2759|Eukaryota,3AGJX@33154|Opisthokonta,3BG52@33208|Metazoa,3CS67@33213|Bilateria,483S5@7711|Chordata,48VR8@7742|Vertebrata,3JFDW@40674|Mammalia,35B1E@314146|Euarchontoglires	33208|Metazoa	U	Sec23/Sec24 trunk domain	SEC24B	GO:0002376,GO:0002474,GO:0002478,GO:0002495,GO:0002504,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005798,GO:0005829,GO:0006810,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006996,GO:0008150,GO:0008270,GO:0009987,GO:0012505,GO:0012506,GO:0012507,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0019882,GO:0019884,GO:0019886,GO:0022607,GO:0030117,GO:0030120,GO:0030127,GO:0030133,GO:0030134,GO:0030135,GO:0030658,GO:0030659,GO:0030660,GO:0030662,GO:0031090,GO:0031410,GO:0031982,GO:0031984,GO:0032991,GO:0033218,GO:0034622,GO:0035459,GO:0042175,GO:0042277,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0046872,GO:0046907,GO:0046914,GO:0048002,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048475,GO:0051179,GO:0051234,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0051668,GO:0061024,GO:0065003,GO:0071840,GO:0090110,GO:0090114,GO:0097708,GO:0098588,GO:0098796,GO:0098805,GO:0098827	-	ko:K14007	ko04141,map04141	M00404	-	-	ko00000,ko00001,ko00002,ko04131	-	-	-	Gelsolin,Sec23_BS,Sec23_helical,Sec23_trunk,zf-Sec23_Sec24
SHD3_k127_3086149_23	1032480.MLP_13190	3.06e-06	59.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4DWSC@85009|Propionibacteriales	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_3086149_8	1192034.CAP_5535	1.972e-65	229.0	COG1847@1|root,COG1847@2|Bacteria,1RB1P@1224|Proteobacteria,42QPK@68525|delta/epsilon subdivisions,2WN58@28221|Deltaproteobacteria,2YW74@29|Myxococcales	28221|Deltaproteobacteria	S	R3H domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
SHD3_k127_3086149_2	1254432.SCE1572_15085	1.839e-139	463.0	COG0706@1|root,COG0706@2|Bacteria,1MV5M@1224|Proteobacteria,42MS8@68525|delta/epsilon subdivisions,2WJB6@28221|Deltaproteobacteria,2YV0H@29|Myxococcales	28221|Deltaproteobacteria	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
SHD3_k127_3086149_20	399739.Pmen_4540	1.54e-23	111.0	COG0759@1|root,COG0759@2|Bacteria,1N6U4@1224|Proteobacteria,1SCG6@1236|Gammaproteobacteria,1YGXT@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
SHD3_k127_3086149_19	448385.sce2522	3.211e-26	112.0	COG0594@1|root,COG0594@2|Bacteria,1NGQJ@1224|Proteobacteria,42VBC@68525|delta/epsilon subdivisions,2WRF0@28221|Deltaproteobacteria,2YVYX@29|Myxococcales	28221|Deltaproteobacteria	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
SHD3_k127_3086149_22	1231241.Mc24_04355	6.664e-12	68.0	COG0230@1|root,COG0230@2|Bacteria,2GDMP@200918|Thermotogae	200918|Thermotogae	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
SHD3_k127_3086149_21	1283300.ATXB01000001_gene2018	1.933e-17	83.0	COG0267@1|root,COG0267@2|Bacteria,1N6QV@1224|Proteobacteria,1SCEJ@1236|Gammaproteobacteria,1XFR0@135618|Methylococcales	135618|Methylococcales	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SHD3_k127_3086149_3	1192034.CAP_5528	7.013e-138	457.0	COG2885@1|root,COG2885@2|Bacteria,1NB27@1224|Proteobacteria	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OmpA
SHD3_k127_3086149_7	1254432.SCE1572_44200	8.726e-92	316.0	COG2340@1|root,COG2340@2|Bacteria,1REVB@1224|Proteobacteria,4386P@68525|delta/epsilon subdivisions,2X3GI@28221|Deltaproteobacteria,2YW01@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SHD3_k127_3086149_12	448385.sce7646	1.183e-46	181.0	COG1463@1|root,COG1463@2|Bacteria,1RFFS@1224|Proteobacteria,42P4P@68525|delta/epsilon subdivisions,2WNNQ@28221|Deltaproteobacteria,2YUZI@29|Myxococcales	28221|Deltaproteobacteria	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
SHD3_k127_3088774_1	391625.PPSIR1_00897	2.239e-145	481.0	COG0497@1|root,COG0497@2|Bacteria,1MUNP@1224|Proteobacteria,42N50@68525|delta/epsilon subdivisions,2WJ23@28221|Deltaproteobacteria,2YTSW@29|Myxococcales	28221|Deltaproteobacteria	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
SHD3_k127_3088774_3	243233.MCA0141	1.853e-66	233.0	COG1881@1|root,COG1881@2|Bacteria,1N0Y4@1224|Proteobacteria,1S400@1236|Gammaproteobacteria,1XF3U@135618|Methylococcales	135618|Methylococcales	S	PFAM Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
SHD3_k127_3088774_0	4787.PITG_22685T0	2.486e-256	800.0	COG0129@1|root,KOG2448@2759|Eukaryota,3QAAT@4776|Peronosporales	4776|Peronosporales	E	Dehydratase family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
SHD3_k127_3088774_5	40215.BBOS01000075_gene2217	3.643e-09	66.0	COG0695@1|root,COG0695@2|Bacteria,1N72P@1224|Proteobacteria,1SCA2@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	grxC	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681	-	ko:K03676	-	-	-	-	ko00000,ko03110	-	-	-	Glutaredoxin
SHD3_k127_3088774_6	857087.Metme_4329	2.671e-08	64.0	2DWID@1|root,340GN@2|Bacteria,1ND9Q@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3088774_2	665571.STHERM_c03630	1.85e-72	245.0	COG0432@1|root,COG0432@2|Bacteria,2J7PN@203691|Spirochaetes	203691|Spirochaetes	S	Secondary thiamine-phosphate synthase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	UPF0047
SHD3_k127_3088774_8	570268.ANBB01000045_gene1142	0.0003375	53.0	COG4260@1|root,COG4260@2|Bacteria,2HUEV@201174|Actinobacteria,4EP9H@85012|Streptosporangiales	201174|Actinobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,SHOCT
SHD3_k127_3088774_7	1192034.CAP_1747	9.197e-06	59.0	COG3170@1|root,COG3170@2|Bacteria,1QX3V@1224|Proteobacteria,43BWB@68525|delta/epsilon subdivisions,2X773@28221|Deltaproteobacteria,2YVT2@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SHD3_k127_3091711_10	448385.sce4436	5.22e-30	121.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,2YV3E@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
SHD3_k127_3091711_5	448385.sce4435	4.732e-62	220.0	COG4752@1|root,COG4752@2|Bacteria,1RJ2G@1224|Proteobacteria,42SXX@68525|delta/epsilon subdivisions,2WP1I@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SAM-dependent RNA methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrn_RNA_4
SHD3_k127_3091711_3	1254432.SCE1572_27100	3.129e-65	235.0	COG1560@1|root,COG1560@2|Bacteria,1R03A@1224|Proteobacteria,43CQI@68525|delta/epsilon subdivisions,2X7XZ@28221|Deltaproteobacteria,2Z27Y@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial lipid A biosynthesis acyltransferase	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Lip_A_acyltrans
SHD3_k127_3091711_8	448385.sce4432	9.886e-35	141.0	COG1801@1|root,COG1801@2|Bacteria	2|Bacteria	L	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SHD3_k127_3091711_11	448385.sce4430	1.212e-25	107.0	COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,437HJ@68525|delta/epsilon subdivisions,2WSUJ@28221|Deltaproteobacteria,2YW0Q@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
SHD3_k127_3091711_1	448385.sce4428	1.746e-86	296.0	COG3741@1|root,COG3741@2|Bacteria,1MY4D@1224|Proteobacteria,43EZM@68525|delta/epsilon subdivisions,2X2S3@28221|Deltaproteobacteria,2Z1PB@29|Myxococcales	28221|Deltaproteobacteria	E	N-formylglutamate amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FGase
SHD3_k127_3091711_9	1192034.CAP_6604	2.227e-33	136.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_3091711_0	1192034.CAP_3429	6.532e-102	348.0	COG4974@1|root,COG4974@2|Bacteria,1MVNF@1224|Proteobacteria,42N0M@68525|delta/epsilon subdivisions,2WJ7D@28221|Deltaproteobacteria,2YZDB@29|Myxococcales	28221|Deltaproteobacteria	D	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SHD3_k127_3091711_7	404589.Anae109_0373	8.364e-45	172.0	COG0134@1|root,COG0134@2|Bacteria,1MW5K@1224|Proteobacteria,42MAG@68525|delta/epsilon subdivisions,2WM94@28221|Deltaproteobacteria,2YV8U@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the TrpC family	trpC	-	4.1.1.48,5.3.1.24	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508,R03509	RC00944,RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2494	IGPS
SHD3_k127_3091711_2	1502851.FG93_03569	5.76e-81	287.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,3JVIJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
SHD3_k127_3091711_4	498761.HM1_1917	2.752e-64	222.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia	186801|Clostridia	EH	TIGRFAM glutamine amidotransferase of anthranilate synthase	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SHD3_k127_309314_4	1254432.SCE1572_05290	1.399e-14	79.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_binding_2,FTP,FlgD_ig,PPC,Peptidase_M4,Peptidase_M4_C,RicinB_lectin_2,SBBP,TIG,Trypsin,VCBS
SHD3_k127_309314_3	1254432.SCE1572_35755	1.848e-71	255.0	COG0491@1|root,COG0491@2|Bacteria,1MUDN@1224|Proteobacteria,42QWD@68525|delta/epsilon subdivisions,2WN14@28221|Deltaproteobacteria,2YVW4@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	ycbL	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SHD3_k127_309314_5	7237.FBpp0280939	3.007e-12	78.0	KOG1217@1|root,KOG3594@1|root,KOG1217@2759|Eukaryota,KOG1219@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera,45X8G@7214|Drosophilidae	33208|Metazoa	T	Worm-specific repeat type 1	-	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA,Zona_pellucida
SHD3_k127_309314_2	309799.DICTH_0008	9.93e-74	265.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,Cellulase
SHD3_k127_309314_1	448385.sce2624	9.352e-136	440.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,42M69@68525|delta/epsilon subdivisions,2WIYC@28221|Deltaproteobacteria,2YWK7@29|Myxococcales	28221|Deltaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SHD3_k127_309314_0	1254432.SCE1572_15700	6.547e-177	569.0	COG0606@1|root,COG0606@2|Bacteria,1MU4R@1224|Proteobacteria,42NBJ@68525|delta/epsilon subdivisions,2WJ52@28221|Deltaproteobacteria,2YTU1@29|Myxococcales	28221|Deltaproteobacteria	O	Magnesium chelatase, subunit ChlI C-terminal	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
SHD3_k127_309314_6	448385.sce1365	4.48e-09	68.0	COG1520@1|root,COG1520@2|Bacteria,1Q2JS@1224|Proteobacteria,4386K@68525|delta/epsilon subdivisions,2X3GH@28221|Deltaproteobacteria,2YVZV@29|Myxococcales	28221|Deltaproteobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SHD3_k127_3094232_4	448385.sce5077	4.447e-53	193.0	COG0817@1|root,COG0817@2|Bacteria,1MUJI@1224|Proteobacteria,42QPX@68525|delta/epsilon subdivisions,2WNF9@28221|Deltaproteobacteria,2YVCN@29|Myxococcales	28221|Deltaproteobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
SHD3_k127_3094232_0	391625.PPSIR1_33429	3.057e-168	542.0	COG1233@1|root,COG1233@2|Bacteria,1MV2R@1224|Proteobacteria,42Y0Z@68525|delta/epsilon subdivisions,2WT7J@28221|Deltaproteobacteria,2YWBV@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SHD3_k127_3094232_3	246197.MXAN_1404	2.569e-101	344.0	COG0707@1|root,COG0707@2|Bacteria,1MWQP@1224|Proteobacteria,42R9T@68525|delta/epsilon subdivisions,2WMWQ@28221|Deltaproteobacteria,2YTYH@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase family 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_3
SHD3_k127_3094232_6	1254432.SCE1572_14060	1.143e-27	123.0	COG1186@1|root,COG1186@2|Bacteria,1RH75@1224|Proteobacteria,42UF8@68525|delta/epsilon subdivisions,2WR6W@28221|Deltaproteobacteria,2Z1VX@29|Myxococcales	28221|Deltaproteobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
SHD3_k127_3094232_1	1254432.SCE1572_30845	3.952e-160	517.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M0V@68525|delta/epsilon subdivisions,2WIQ1@28221|Deltaproteobacteria,2YU4J@29|Myxococcales	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	glcD	-	1.1.2.4,1.1.3.15	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	-	R00197,R00475	RC00042,RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SHD3_k127_3094232_2	502025.Hoch_0991	6.45e-117	386.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SHD3_k127_3094232_5	448385.sce8901	3.388e-37	147.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3094232_11	1254432.SCE1572_45535	9.244e-07	56.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2YUBF@29|Myxococcales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SHD3_k127_3094232_7	864051.BurJ1DRAFT_3207	2.179e-26	119.0	COG0399@1|root,COG0399@2|Bacteria,1MUMJ@1224|Proteobacteria,2VQRJ@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
SHD3_k127_3107212_3	1192034.CAP_8436	3.324e-06	60.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3107212_2	391625.PPSIR1_28078	2.535e-64	228.0	COG0663@1|root,COG0663@2|Bacteria,1RD76@1224|Proteobacteria,42MR0@68525|delta/epsilon subdivisions,2WP23@28221|Deltaproteobacteria,2Z0GF@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SHD3_k127_3107212_1	1192034.CAP_7045	1.439e-92	321.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3107212_0	1192034.CAP_1111	8.841e-139	446.0	COG0620@1|root,COG0620@2|Bacteria,1QTG9@1224|Proteobacteria,43A3S@68525|delta/epsilon subdivisions,2X29J@28221|Deltaproteobacteria,2Z1JZ@29|Myxococcales	28221|Deltaproteobacteria	E	Cobalamin-independent synthase, N-terminal domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1
SHD3_k127_3109786_4	1120950.KB892823_gene572	1.305e-99	335.0	COG0116@1|root,COG0116@2|Bacteria,2I2EM@201174|Actinobacteria	201174|Actinobacteria	L	Putative RNA methylase family UPF0020	-	-	-	-	-	-	-	-	-	-	-	-	UPF0020
SHD3_k127_3109786_9	326427.Cagg_0669	3.718e-08	59.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3109786_0	903818.KI912268_gene1102	6.447e-230	726.0	COG0119@1|root,COG0119@2|Bacteria	2|Bacteria	E	Belongs to the alpha-IPM synthase homocitrate synthase family	leuA	GO:0000287,GO:0003674,GO:0003824,GO:0003852,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0019752,GO:0030145,GO:0030955,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0046912,GO:0046914,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iYL1228.KPN_03016	HMGL-like,LeuA_dimer
SHD3_k127_3109786_3	1267535.KB906767_gene67	6.192e-115	387.0	COG1007@1|root,COG1007@2|Bacteria,3Y3PV@57723|Acidobacteria,2JIT3@204432|Acidobacteriia	204432|Acidobacteriia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	Proton_antipo_M
SHD3_k127_3109786_2	1123368.AUIS01000006_gene666	3.721e-178	582.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,1RNI4@1236|Gammaproteobacteria,2NCKR@225057|Acidithiobacillales	1236|Gammaproteobacteria	C	Proton-conducting membrane transporter	nuoM	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iSDY_1059.SDY_2473	Proton_antipo_M
SHD3_k127_3109786_1	323261.Noc_1117	2.199e-212	677.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,1RNKN@1236|Gammaproteobacteria,1WWQ6@135613|Chromatiales	135613|Chromatiales	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
SHD3_k127_3109786_8	323848.Nmul_A1022	7.16e-36	138.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,2WDWR@28216|Betaproteobacteria,3748W@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SHD3_k127_3109786_7	1123368.AUIS01000006_gene663	1.326e-49	181.0	COG0839@1|root,COG0839@2|Bacteria,1PJWA@1224|Proteobacteria,1TAH9@1236|Gammaproteobacteria,2NDFI@225057|Acidithiobacillales	225057|Acidithiobacillales	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SHD3_k127_3109786_6	1266925.JHVX01000004_gene1247	3.462e-89	296.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,2WBX2@28216|Betaproteobacteria,373YS@32003|Nitrosomonadales	28216|Betaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
SHD3_k127_3109786_5	472759.Nhal_2135	3.94e-99	326.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,1RQE9@1236|Gammaproteobacteria,1WXDH@135613|Chromatiales	135613|Chromatiales	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SHD3_k127_3110017_3	525897.Dbac_2319	1.495e-35	148.0	COG0019@1|root,COG0019@2|Bacteria,1MW3T@1224|Proteobacteria,42MVP@68525|delta/epsilon subdivisions,2WITG@28221|Deltaproteobacteria,2M7Z2@213115|Desulfovibrionales	28221|Deltaproteobacteria	E	Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Ala_racemase_N,Orn_DAP_Arg_deC
SHD3_k127_3110017_0	502025.Hoch_6504	1.84e-204	644.0	COG1748@1|root,COG1748@2|Bacteria,1NIU2@1224|Proteobacteria,42MHS@68525|delta/epsilon subdivisions,2WJQW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Saccharopine dehydrogenase	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0902	Sacchrp_dh_C,Sacchrp_dh_NADP
SHD3_k127_3110017_2	1254432.SCE1572_15560	6.424e-44	168.0	COG0810@1|root,COG0810@2|Bacteria,1QARZ@1224|Proteobacteria,4359H@68525|delta/epsilon subdivisions,2WZKN@28221|Deltaproteobacteria,2Z2BQ@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3110017_1	1254432.SCE1572_36105	7.961e-100	335.0	COG1213@1|root,COG1213@2|Bacteria,1RB54@1224|Proteobacteria,42PKE@68525|delta/epsilon subdivisions,2X99A@28221|Deltaproteobacteria,2Z2QS@29|Myxococcales	28221|Deltaproteobacteria	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
SHD3_k127_3111082_1	345341.KUTG_00701	1.176e-94	320.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria,4E1D9@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	AbfB,ArabFuran-catal,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_3111082_2	452637.Oter_3803	2.966e-90	311.0	COG0845@1|root,COG0845@2|Bacteria,46U1B@74201|Verrucomicrobia,3K78A@414999|Opitutae	414999|Opitutae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	HlyD_D23
SHD3_k127_3111082_0	1232410.KI421412_gene178	0.0	1290.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,43S5E@69541|Desulfuromonadales	28221|Deltaproteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2	-	-	ACR_tran
SHD3_k127_3114905_1	1123242.JH636435_gene894	3.863e-236	747.0	COG1523@1|root,COG1523@2|Bacteria,2IX65@203682|Planctomycetes	203682|Planctomycetes	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,CBM_48
SHD3_k127_3114905_0	1380390.JIAT01000009_gene545	9.263e-269	847.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4CP7U@84995|Rubrobacteria	84995|Rubrobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
SHD3_k127_3114905_2	1192034.CAP_3271	9.763e-31	139.0	COG0515@1|root,COG0515@2|Bacteria,1Q27Z@1224|Proteobacteria,437UY@68525|delta/epsilon subdivisions,2X34F@28221|Deltaproteobacteria,2YU7K@29|Myxococcales	28221|Deltaproteobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SHD3_k127_3114905_4	158189.SpiBuddy_2037	6.127e-13	77.0	COG1418@1|root,COG1418@2|Bacteria	2|Bacteria	S	mRNA catabolic process	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SHD3_k127_3114905_5	215803.DB30_1840	1.724e-10	72.0	COG4305@1|root,COG4305@2|Bacteria,1MYW4@1224|Proteobacteria	1224|Proteobacteria	G	Lytic transglycolase	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	CBM_2,Cellulase,DPBB_1,Pollen_allerg_1
SHD3_k127_3114905_3	391625.PPSIR1_05303	5.865e-29	126.0	2A4BQ@1|root,30SXD@2|Bacteria,1PCFN@1224|Proteobacteria,438EV@68525|delta/epsilon subdivisions,2WYPE@28221|Deltaproteobacteria,2YWSY@29|Myxococcales	28221|Deltaproteobacteria	S	IgGFc binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IgGFc_binding
SHD3_k127_311576_1	658187.LDG_5899	4.976e-11	74.0	COG1652@1|root,COG3209@1|root,COG1652@2|Bacteria,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,1SKYM@1236|Gammaproteobacteria,1JCV3@118969|Legionellales	118969|Legionellales	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	LysM,RHS_repeat
SHD3_k127_311576_0	642492.Clole_0277	3.395e-46	184.0	COG3266@1|root,COG3266@2|Bacteria,1UIIB@1239|Firmicutes,25F7Q@186801|Clostridia	186801|Clostridia	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SHD3_k127_311576_2	1192034.CAP_1626	0.0006045	51.0	COG4969@1|root,COG4969@2|Bacteria	2|Bacteria	NU	cell adhesion	-	-	-	-	-	-	-	-	-	-	-	-	DUF4845,Pilin_GH
SHD3_k127_3128457_2	335543.Sfum_2436	9.288e-48	182.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2MRTA@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798,ko:K15727	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1,8.A.1.2.1	-	-	DUF3347,HlyD_D23
SHD3_k127_3128457_0	671143.DAMO_0963	0.0	1427.0	COG3696@1|root,COG3696@2|Bacteria,2NNKZ@2323|unclassified Bacteria	2|Bacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	cusA	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SHD3_k127_3128457_1	335543.Sfum_2246	0.0	1262.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2MRHY@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SHD3_k127_314172_4	1192034.CAP_4453	5.143e-168	542.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YUJY@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SHD3_k127_314172_12	448385.sce6502	4.375e-130	421.0	COG1721@1|root,COG1721@2|Bacteria,1Q7RR@1224|Proteobacteria,42PJB@68525|delta/epsilon subdivisions,2WK1X@28221|Deltaproteobacteria,2YURN@29|Myxococcales	28221|Deltaproteobacteria	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SHD3_k127_314172_16	448385.sce6503	9.547e-93	326.0	2DQMB@1|root,337KD@2|Bacteria,1NKJH@1224|Proteobacteria,42X0X@68525|delta/epsilon subdivisions,2WSJT@28221|Deltaproteobacteria,2YVNT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_314172_9	1254432.SCE1572_38500	8.657e-137	445.0	COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,42NWB@68525|delta/epsilon subdivisions,2WKKE@28221|Deltaproteobacteria,2YXC9@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	batA	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA
SHD3_k127_314172_10	1192034.CAP_4449	8.858e-133	450.0	COG2304@1|root,COG2304@2|Bacteria,1MW51@1224|Proteobacteria,42M45@68525|delta/epsilon subdivisions,2WM19@28221|Deltaproteobacteria,2YV46@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	batB	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,TPR_1,TPR_16,TPR_2,VWA,VWA_2
SHD3_k127_314172_24	1192034.CAP_4448	1.739e-62	241.0	COG0457@1|root,COG0457@2|Bacteria,1PYTB@1224|Proteobacteria,42VYS@68525|delta/epsilon subdivisions,2XA0E@28221|Deltaproteobacteria,2YW26@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2
SHD3_k127_314172_14	448385.sce6507	1.639e-99	351.0	COG0457@1|root,COG0457@2|Bacteria,1MXK4@1224|Proteobacteria,42PK9@68525|delta/epsilon subdivisions,2WM9F@28221|Deltaproteobacteria,2YVH9@29|Myxococcales	28221|Deltaproteobacteria	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
SHD3_k127_314172_28	448385.sce6508	3.681e-52	198.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce6508|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_314172_18	1396141.BATP01000030_gene3653	5.109e-82	277.0	COG1335@1|root,COG1335@2|Bacteria,46UUK@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	isochorismatase hydrolase	-	-	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
SHD3_k127_314172_3	338963.Pcar_1714	1.081e-189	632.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,43S9Z@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SHD3_k127_314172_36	1192034.CAP_8125	8.133e-05	54.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,42PKU@68525|delta/epsilon subdivisions,2WM5K@28221|Deltaproteobacteria,2YZUC@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
SHD3_k127_314172_31	387093.SUN_0789	1.255e-08	66.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2YMM8@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	P	cation transport ATPase	copA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
SHD3_k127_314172_7	661478.OP10G_4690	4.273e-145	468.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	yrpG	-	-	ko:K13315	ko00523,ko01130,map00523,map01130	M00798,M00799	R11051,R11474	RC00897,RC01516	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
SHD3_k127_314172_27	28444.JODQ01000007_gene5157	1.59e-53	211.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,4EGMA@85012|Streptosporangiales	201174|Actinobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
SHD3_k127_314172_37	633.DJ40_3245	0.0001542	50.0	COG2979@1|root,COG2979@2|Bacteria,1R95E@1224|Proteobacteria,1S2WZ@1236|Gammaproteobacteria,41FH0@629|Yersinia	1236|Gammaproteobacteria	S	Protein of unknown function (DUF533)	yebE	-	-	-	-	-	-	-	-	-	-	-	DUF533
SHD3_k127_314172_15	1254432.SCE1572_45965	2.245e-95	321.0	COG0164@1|root,COG0164@2|Bacteria	2|Bacteria	L	RNA-DNA hybrid ribonuclease activity	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SHD3_k127_314172_20	502025.Hoch_5887	3.493e-70	264.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42RC9@68525|delta/epsilon subdivisions,2WN5U@28221|Deltaproteobacteria,2YWJ8@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,PEGA,Pkinase
SHD3_k127_314172_30	880071.Fleli_3602	9.844e-22	110.0	2E9WW@1|root,3342M@2|Bacteria,4P592@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_314172_8	391625.PPSIR1_02256	1.498e-141	479.0	COG2304@1|root,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,42NNC@68525|delta/epsilon subdivisions,2WKQW@28221|Deltaproteobacteria,2Z33Y@29|Myxococcales	28221|Deltaproteobacteria	M	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VIT,VWA_3
SHD3_k127_314172_0	1254432.SCE1572_06940	3.425e-268	838.0	COG1217@1|root,COG1217@2|Bacteria,1MV5Q@1224|Proteobacteria,42M3S@68525|delta/epsilon subdivisions,2WJVZ@28221|Deltaproteobacteria,2YU94@29|Myxococcales	28221|Deltaproteobacteria	T	GTP-binding protein	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
SHD3_k127_314172_35	3760.EMJ15168	3.718e-06	61.0	2BN3S@1|root,2S1NG@2759|Eukaryota,37VHH@33090|Viridiplantae,3GJNP@35493|Streptophyta,4JU6P@91835|fabids	35493|Streptophyta	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_314172_23	502025.Hoch_1734	1.835e-63	246.0	COG3203@1|root,COG3203@2|Bacteria	2|Bacteria	M	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Porin_4
SHD3_k127_314172_34	4641.GSMUA_Achr5P21130_001	2.822e-06	61.0	2BN3S@1|root,2S1NG@2759|Eukaryota,37VHH@33090|Viridiplantae,3GJNP@35493|Streptophyta,3M7MI@4447|Liliopsida	35493|Streptophyta	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_314172_38	608506.COB47_1671	0.0004044	54.0	COG2730@1|root,COG3266@1|root,COG3693@1|root,COG2730@2|Bacteria,COG3266@2|Bacteria,COG3693@2|Bacteria,1UK4A@1239|Firmicutes,248JY@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase,Dockerin_1
SHD3_k127_314172_33	864073.HFRIS_009969	6.898e-08	63.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2VIT4@28216|Betaproteobacteria,476HQ@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Phosphate regulon two-component response regulator transcription regulator protein	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_314172_29	1254432.SCE1572_10070	1.986e-42	176.0	2AH4I@1|root,317E5@2|Bacteria,1PYQB@1224|Proteobacteria,435HF@68525|delta/epsilon subdivisions,2X99V@28221|Deltaproteobacteria,2Z2T7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_314172_5	448385.sce9006	3.905e-162	521.0	COG1816@1|root,COG1816@2|Bacteria,1MWBV@1224|Proteobacteria,42UJZ@68525|delta/epsilon subdivisions,2WQCC@28221|Deltaproteobacteria,2YV77@29|Myxococcales	28221|Deltaproteobacteria	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	-	A_deaminase
SHD3_k127_314172_26	999419.HMPREF1077_03518	1.254e-54	197.0	COG1443@1|root,COG1443@2|Bacteria,4NJUP@976|Bacteroidetes,2FNMR@200643|Bacteroidia,22XUF@171551|Porphyromonadaceae	976|Bacteroidetes	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	IspA,NUDIX
SHD3_k127_314172_21	1040986.ATYO01000007_gene1065	7.305e-65	233.0	COG0053@1|root,COG0053@2|Bacteria,1MVH8@1224|Proteobacteria,2TVQV@28211|Alphaproteobacteria,43HC5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SHD3_k127_314172_17	448385.sce7618	2.309e-91	308.0	COG1708@1|root,COG1708@2|Bacteria,1NKZT@1224|Proteobacteria,430VC@68525|delta/epsilon subdivisions,2WVUS@28221|Deltaproteobacteria,2Z164@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterised protein family (UPF0158)	-	-	-	-	-	-	-	-	-	-	-	-	UPF0158
SHD3_k127_314172_6	1380356.JNIK01000021_gene4464	1.375e-147	487.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4EREP@85013|Frankiales	201174|Actinobacteria	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
SHD3_k127_314172_1	448385.sce7616	1.271e-237	749.0	COG1716@1|root,COG2114@1|root,COG2203@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,COG2203@2|Bacteria,1RAHZ@1224|Proteobacteria,42UGY@68525|delta/epsilon subdivisions,2WQPI@28221|Deltaproteobacteria,2YUG9@29|Myxococcales	28221|Deltaproteobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	FHA,GAF,GAF_2,Guanylate_cyc
SHD3_k127_314172_11	448385.sce7615	2.513e-132	429.0	COG0825@1|root,COG0825@2|Bacteria,1MURN@1224|Proteobacteria,42NC2@68525|delta/epsilon subdivisions,2WKA3@28221|Deltaproteobacteria,2YU4X@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA	accA	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA
SHD3_k127_314172_2	204669.Acid345_3284	3.914e-201	638.0	COG0531@1|root,COG0531@2|Bacteria,3Y3SZ@57723|Acidobacteria,2JI7T@204432|Acidobacteriia	204432|Acidobacteriia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
SHD3_k127_314172_13	1254432.SCE1572_21550	5.446e-116	386.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_314172_19	1254432.SCE1572_30065	5.155e-78	280.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_3145791_0	1304880.JAGB01000003_gene1278	1.32e-318	989.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia	186801|Clostridia	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_3158696_3	78898.MVEG_00454T0	4.726e-18	84.0	COG1949@1|root,KOG3242@2759|Eukaryota,39R06@33154|Opisthokonta,3NYIP@4751|Fungi,1GTS4@112252|Fungi incertae sedis	4751|Fungi	L	EXOIII	rex2	GO:0000002,GO:0000175,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016073,GO:0016180,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034472,GO:0034475,GO:0034476,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
SHD3_k127_3158696_2	945713.IALB_1235	6.869e-29	127.0	28J1N@1|root,2Z8YI@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SHD3_k127_3158696_4	330214.NIDE3859	0.0003573	48.0	COG0071@1|root,COG0071@2|Bacteria,3J0TV@40117|Nitrospirae	40117|Nitrospirae	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SHD3_k127_3158696_0	765910.MARPU_10595	0.0	1616.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,1WX8F@135613|Chromatiales	135613|Chromatiales	F	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS_C,GATase_5
SHD3_k127_3158696_1	38833.XP_003058487.1	1.572e-162	554.0	COG0574@1|root,2QQ6R@2759|Eukaryota,37KSG@33090|Viridiplantae,34GN6@3041|Chlorophyta	3041|Chlorophyta	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	GWD1	-	2.7.9.4	ko:K08244	-	-	-	-	ko00000,ko01000	-	-	-	PPDK_N
SHD3_k127_316582_2	448385.sce2553	4.882e-76	263.0	COG0020@1|root,COG0020@2|Bacteria,1MVP1@1224|Proteobacteria,42PTV@68525|delta/epsilon subdivisions,2WMWK@28221|Deltaproteobacteria,2YUTJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
SHD3_k127_316582_4	1192034.CAP_5455	1.644e-36	141.0	COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,43EDJ@68525|delta/epsilon subdivisions,2X82C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GHKL domain	-	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SHD3_k127_316582_0	1254432.SCE1572_15295	7.318e-98	331.0	COG0642@1|root,COG0642@2|Bacteria,1QU3Z@1224|Proteobacteria,43EDJ@68525|delta/epsilon subdivisions,2X82C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	GHKL domain	-	-	2.7.13.3	ko:K07641	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SHD3_k127_316582_1	448385.sce2555	5.383e-93	315.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42UVV@68525|delta/epsilon subdivisions,2WUTB@28221|Deltaproteobacteria,2YUY6@29|Myxococcales	28221|Deltaproteobacteria	K	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_316582_3	1254432.SCE1572_46675	3.965e-43	165.0	COG2969@1|root,COG2969@2|Bacteria,1R39Y@1224|Proteobacteria,43DJU@68525|delta/epsilon subdivisions,2X8R3@28221|Deltaproteobacteria,2YW22@29|Myxococcales	28221|Deltaproteobacteria	S	Stringent starvation protein B	-	-	-	ko:K03600	-	-	-	-	ko00000,ko03021	-	-	-	SspB
SHD3_k127_316582_5	448385.sce8703	1.105e-32	131.0	COG0457@1|root,COG0457@2|Bacteria,1QQ0R@1224|Proteobacteria,433U8@68525|delta/epsilon subdivisions,2X3GZ@28221|Deltaproteobacteria,2YW20@29|Myxococcales	28221|Deltaproteobacteria	S	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,zinc_ribbon_4
SHD3_k127_3166429_0	497964.CfE428DRAFT_6157	1.016e-65	256.0	COG1361@1|root,COG1520@1|root,COG1572@1|root,COG3291@1|root,COG3391@1|root,COG4932@1|root,COG4934@1|root,COG1361@2|Bacteria,COG1520@2|Bacteria,COG1572@2|Bacteria,COG3291@2|Bacteria,COG3391@2|Bacteria,COG4932@2|Bacteria,COG4934@2|Bacteria	2|Bacteria	O	collagen metabolic process	-	-	-	ko:K08677	-	-	-	-	ko00000,ko01002	-	-	-	CHU_C,DUF11,Pro-kuma_activ,SdrD_B
SHD3_k127_3166429_1	357808.RoseRS_0421	1.45e-35	158.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_3166913_6	391625.PPSIR1_29633	6.45e-18	92.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigH	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_3166913_10	525898.Sdel_1225	2.038e-05	57.0	COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria,42YII@68525|delta/epsilon subdivisions,2YR8I@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	PT	Domain of unknown function (DUF4974)	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
SHD3_k127_3166913_8	68219.JNXI01000054_gene182	8.005e-09	69.0	COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria	201174|Actinobacteria	E	Zinc metalloprotease (Elastase)	-	-	-	-	-	-	-	-	-	-	-	-	Sortilin-Vps10
SHD3_k127_3166913_7	314345.SPV1_00887	6.467e-10	71.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3166913_2	1192034.CAP_0180	2.805e-57	218.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG5373@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,COG5373@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_7,TPR_8
SHD3_k127_3166913_4	448385.sce0618	2.55e-33	144.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	bscD	-	-	ko:K03220	-	M00332	-	-	ko00000,ko00002,ko02044	3.A.6.1	-	-	FHA
SHD3_k127_3166913_3	448385.sce3444	2.583e-55	207.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SHD3_k127_3166913_5	1278073.MYSTI_06160	3.493e-29	122.0	COG3030@1|root,COG3030@2|Bacteria,1MZJJ@1224|Proteobacteria,42VMT@68525|delta/epsilon subdivisions,2WPFB@28221|Deltaproteobacteria,2YVIK@29|Myxococcales	28221|Deltaproteobacteria	S	FxsA cytoplasmic membrane protein	fsxA	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
SHD3_k127_3166913_1	1192034.CAP_6903	5.918e-104	352.0	COG0484@1|root,COG0484@2|Bacteria,1QXUZ@1224|Proteobacteria,43C7N@68525|delta/epsilon subdivisions,2X7HY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
SHD3_k127_3166913_0	448385.sce3750	9.411e-248	781.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2YU4G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SHD3_k127_3170900_1	1123508.JH636459_gene178	8.257e-126	432.0	COG0642@1|root,COG0784@1|root,COG4191@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,PAS_9,Response_reg
SHD3_k127_3170900_3	926562.Oweho_0029	1.12e-15	85.0	2ATWF@1|root,31JFP@2|Bacteria,4NT3Q@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3170900_2	762376.AXYL_05381	1.178e-38	156.0	2C3WA@1|root,2Z8P1@2|Bacteria,1R8VC@1224|Proteobacteria,2VQ8D@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3170900_0	1487953.JMKF01000091_gene5284	0.0	1310.0	COG3119@1|root,COG3119@2|Bacteria,1G3QV@1117|Cyanobacteria	1117|Cyanobacteria	P	COG3119 Arylsulfatase A and related enzymes	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
SHD3_k127_3179006_2	290397.Adeh_3027	0.0007058	43.0	COG0702@1|root,COG0702@2|Bacteria,1PDTN@1224|Proteobacteria,42M8X@68525|delta/epsilon subdivisions,2WJ5J@28221|Deltaproteobacteria,2Z22B@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
SHD3_k127_3179006_1	1122604.JONR01000011_gene3684	4.545e-13	73.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,1RQE4@1236|Gammaproteobacteria,1X59Z@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SHD3_k127_3179006_0	1254432.SCE1572_09725	1.66e-22	115.0	COG5297@1|root,COG5297@2|Bacteria,1NRKN@1224|Proteobacteria,43EDP@68525|delta/epsilon subdivisions,2X82I@28221|Deltaproteobacteria,2YWBM@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3187470_0	861299.J421_5728	1.652e-86	313.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SHD3_k127_3187470_2	1280944.HY17_11145	2.923e-14	87.0	COG0457@1|root,COG3710@1|root,COG5616@1|root,COG0457@2|Bacteria,COG3710@2|Bacteria,COG5616@2|Bacteria,1PF3H@1224|Proteobacteria,2V7F9@28211|Alphaproteobacteria,43YSF@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,Trans_reg_C
SHD3_k127_3187470_1	234267.Acid_5780	2.581e-68	260.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,TPR_12,TPR_8,Trans_reg_C
SHD3_k127_3187470_3	316274.Haur_1450	7.894e-07	60.0	COG0515@1|root,COG2199@1|root,COG2203@1|root,COG2909@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG2909@2|Bacteria,COG3706@2|Bacteria,COG3899@2|Bacteria,2G87Y@200795|Chloroflexi,377XF@32061|Chloroflexia	32061|Chloroflexia	KT	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SHD3_k127_3190405_1	391625.PPSIR1_40050	5.285e-18	94.0	2C0JI@1|root,33E1V@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4013)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4013
SHD3_k127_3192419_3	41431.PCC8801_2029	2.138e-31	141.0	COG0451@1|root,COG0451@2|Bacteria,1G2DP@1117|Cyanobacteria,3KG36@43988|Cyanothece	1117|Cyanobacteria	M	PFAM NAD-dependent epimerase dehydratase	dfrA	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SHD3_k127_3192419_0	1125863.JAFN01000001_gene303	1.041e-106	366.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42QS7@68525|delta/epsilon subdivisions,2X74U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	AMP-binding enzyme	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,Acyltransferase,PP-binding
SHD3_k127_3192419_1	667014.Thein_0379	4.472e-102	345.0	COG0304@1|root,COG0304@2|Bacteria,2GH5C@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SHD3_k127_3192419_2	215803.DB30_0196	3.549e-96	334.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,4377E@68525|delta/epsilon subdivisions,2X289@28221|Deltaproteobacteria,2YUWN@29|Myxococcales	28221|Deltaproteobacteria	S	Von Willebrand factor type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SHD3_k127_319347_4	1121861.KB899936_gene351	2.817e-24	110.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,2U9N6@28211|Alphaproteobacteria,2JSQS@204441|Rhodospirillales	204441|Rhodospirillales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
SHD3_k127_319347_7	1307761.L21SP2_2883	3.324e-18	87.0	arCOG15062@1|root,32Y8D@2|Bacteria,2J908@203691|Spirochaetes	203691|Spirochaetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PQ-loop
SHD3_k127_319347_3	1261545.MBE-HAL_2094	9.463e-69	247.0	COG0115@1|root,arCOG02297@2157|Archaea,2XT9V@28890|Euryarchaeota,23SQX@183963|Halobacteria	183963|Halobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SHD3_k127_319347_1	502025.Hoch_0461	3.785e-118	392.0	COG1916@1|root,COG1916@2|Bacteria,1MWJ0@1224|Proteobacteria,42P2H@68525|delta/epsilon subdivisions,2WJQM@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM TraB determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	TraB
SHD3_k127_319347_2	234267.Acid_5283	3.747e-104	350.0	COG0436@1|root,COG0436@2|Bacteria,3Y2VQ@57723|Acidobacteria	57723|Acidobacteria	E	PFAM Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
SHD3_k127_319347_8	287.DR97_3551	2.536e-13	78.0	COG1539@1|root,COG1539@2|Bacteria,1MZ8Z@1224|Proteobacteria,1S9B2@1236|Gammaproteobacteria,1YGCA@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802	1.13.11.81,4.1.2.25,5.1.99.8	ko:K01633	ko00790,ko01100,map00790,map01100	M00126,M00840	R03504,R11037,R11073	RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	iECDH1ME8569_1439.ECDH1ME8569_2955,iECSE_1348.ECSE_3338,iPC815.YPO0648,iSBO_1134.SBO_2914,iSDY_1059.SDY_3241,iSFxv_1172.SFxv_3403,iUTI89_1310.UTI89_C3494,iYL1228.KPN_03462,ic_1306.c3808	FolB
SHD3_k127_319347_0	290397.Adeh_1141	1.943e-143	480.0	COG3590@1|root,COG3590@2|Bacteria,1MVNQ@1224|Proteobacteria,42S4X@68525|delta/epsilon subdivisions,2WNPW@28221|Deltaproteobacteria,2YU9Y@29|Myxococcales	28221|Deltaproteobacteria	O	Peptidase family M13	-	-	3.4.24.71	ko:K01415,ko:K07386	-	-	-	-	ko00000,ko01000,ko01002,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
SHD3_k127_3214069_2	1121861.KB899926_gene2638	1.885e-134	447.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TRE4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	dna methylase	-	-	2.1.1.72	ko:K00571,ko:K07316	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
SHD3_k127_3214069_8	1125863.JAFN01000001_gene1836	3.75e-27	117.0	COG1917@1|root,COG1917@2|Bacteria,1RJX2@1224|Proteobacteria,42TVK@68525|delta/epsilon subdivisions,2WQ2T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SHD3_k127_3214069_13	290397.Adeh_3688	5.128e-05	57.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria,1NVZF@1224|Proteobacteria,42ZUK@68525|delta/epsilon subdivisions,2X7NR@28221|Deltaproteobacteria,2Z3H7@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,Response_reg
SHD3_k127_3214069_0	1192034.CAP_3830	4.955e-180	581.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YZC4@29|Myxococcales	28221|Deltaproteobacteria	T	Sigma-54 interaction domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Response_reg,Sigma54_activat
SHD3_k127_3214069_3	1192034.CAP_3831	5.447e-81	286.0	COG0642@1|root,COG2205@2|Bacteria	1192034.CAP_3831|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3214069_12	66874.JOFS01000017_gene3535	2.815e-05	56.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_3214069_11	525897.Dbac_2092	1.609e-05	57.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1MUY7@1224|Proteobacteria,43CZY@68525|delta/epsilon subdivisions,2X887@28221|Deltaproteobacteria,2MHCZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	histidine kinase HAMP region domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9
SHD3_k127_3214069_1	448385.sce0950	1.31e-154	509.0	COG3119@1|root,COG3119@2|Bacteria,1QZST@1224|Proteobacteria,43CMS@68525|delta/epsilon subdivisions,2X7UX@28221|Deltaproteobacteria,2Z29A@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SHD3_k127_3214069_6	1163617.SCD_n00309	8.51e-62	223.0	COG0500@1|root,COG2226@2|Bacteria,1RDI3@1224|Proteobacteria	1224|Proteobacteria	Q	Pfam Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
SHD3_k127_3214069_10	1192034.CAP_8715	3e-24	115.0	2DBMC@1|root,2Z9YC@2|Bacteria,1PY40@1224|Proteobacteria,43E0Z@68525|delta/epsilon subdivisions,2WZDV@28221|Deltaproteobacteria,2Z1X8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3214069_7	1278073.MYSTI_01269	3.296e-32	127.0	COG2261@1|root,COG2261@2|Bacteria,1N72Y@1224|Proteobacteria,42X0E@68525|delta/epsilon subdivisions,2WTFH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Transglycosylase-associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SHD3_k127_3214069_5	748247.AZKH_2167	7.482e-68	240.0	COG2816@1|root,COG2816@2|Bacteria,1QGCX@1224|Proteobacteria,2VQIR@28216|Betaproteobacteria,2KW28@206389|Rhodocyclales	206389|Rhodocyclales	L	NADH pyrophosphatase-like rudimentary NUDIX domain	-	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
SHD3_k127_3214069_14	215803.DB30_6675	0.0004987	51.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4346X@68525|delta/epsilon subdivisions,2XA3R@28221|Deltaproteobacteria,2YXWE@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TonB_C
SHD3_k127_3237840_2	404589.Anae109_4286	3.208e-70	254.0	COG4258@1|root,COG4258@2|Bacteria,1QX7Z@1224|Proteobacteria,43C13@68525|delta/epsilon subdivisions,2X7BR@28221|Deltaproteobacteria,2YU55@29|Myxococcales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SHD3_k127_3237840_0	448385.sce1523	4.137e-274	859.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,42NE9@68525|delta/epsilon subdivisions,2WKU2@28221|Deltaproteobacteria,2YYXU@29|Myxococcales	28221|Deltaproteobacteria	G	N-terminal domain of (some) glycogen debranching enzymes	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
SHD3_k127_3237840_4	448385.sce6014	1.985e-15	82.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTW0@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K02481,ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_3237840_1	1242864.D187_002575	2.33e-73	265.0	COG0642@1|root,COG2205@2|Bacteria,1N5YU@1224|Proteobacteria,42N55@68525|delta/epsilon subdivisions,2WVAY@28221|Deltaproteobacteria,2YWI6@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_3237840_3	1229172.JQFA01000002_gene2141	5.468e-50	187.0	COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,1GQ4V@1117|Cyanobacteria,1HI04@1150|Oscillatoriales	1117|Cyanobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,PAS_10
SHD3_k127_3243752_15	1449353.JQMQ01000005_gene1098	4.453e-17	95.0	COG1361@1|root,COG3533@1|root,COG1361@2|Bacteria,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,CHU_C,DUF11,IgGFc_binding,LTD,NPCBM_assoc,Peptidase_M11,SprB
SHD3_k127_3243752_3	1254432.SCE1572_02715	6.06e-86	305.0	COG0515@1|root,COG0515@2|Bacteria,1Q38J@1224|Proteobacteria,438ZJ@68525|delta/epsilon subdivisions,2X44T@28221|Deltaproteobacteria,2YY98@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	masK	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3243752_1	65497.JODV01000033_gene1318	4.196e-144	486.0	COG5297@1|root,COG5297@2|Bacteria,2I363@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 28 family	yesW	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SHD3_k127_3243752_17	684949.ATTJ01000001_gene528	3.222e-11	75.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3243752_7	1254432.SCE1572_34115	7.628e-60	220.0	COG0823@1|root,COG0823@2|Bacteria,1RI0N@1224|Proteobacteria	1224|Proteobacteria	U	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14,VPEP
SHD3_k127_3243752_14	1254432.SCE1572_29295	5.707e-24	102.0	COG0745@1|root,COG0745@2|Bacteria,1MVCB@1224|Proteobacteria,42QQJ@68525|delta/epsilon subdivisions,2WMUM@28221|Deltaproteobacteria,2Z2Y5@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483,ko:K07663	ko02020,map02020	M00449	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_3243752_16	1396418.BATQ01000007_gene1447	9.226e-17	91.0	2DR4U@1|root,33A62@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CreD
SHD3_k127_3243752_13	1123308.KB904538_gene247	9.571e-27	128.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli	91061|Bacilli	E	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	livJ	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SHD3_k127_3243752_19	391612.CY0110_12752	4.128e-05	57.0	COG5361@1|root,COG5361@2|Bacteria,1G8PW@1117|Cyanobacteria,3KHNR@43988|Cyanothece	1117|Cyanobacteria	S	Neurotransmitter-gated ion-channel ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Neur_chan_LBD,Neur_chan_memb
SHD3_k127_3243752_2	1254432.SCE1572_51055	6.47e-135	440.0	COG2730@1|root,COG2730@2|Bacteria,1R5GC@1224|Proteobacteria,434P8@68525|delta/epsilon subdivisions,2WZ0H@28221|Deltaproteobacteria,2Z12C@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_3243752_6	926569.ANT_04000	5.886e-73	256.0	COG3868@1|root,COG3868@2|Bacteria	2|Bacteria	S	Glycoside-hydrolase family GH114	-	-	-	ko:K21006	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	Glyco_hydro_114
SHD3_k127_3243752_4	1907.SGLAU_30675	5.432e-84	287.0	COG3828@1|root,COG3828@2|Bacteria,2GJW0@201174|Actinobacteria	201174|Actinobacteria	M	Trehalose utilisation	-	-	-	ko:K09992	-	-	-	-	ko00000	-	-	-	CBM_6,Glyco_hydro_99,ThuA
SHD3_k127_3243752_9	1254432.SCE1572_05770	4.268e-57	205.0	2A4VM@1|root,30TH8@2|Bacteria,1PDC0@1224|Proteobacteria,435FP@68525|delta/epsilon subdivisions,2WZT7@28221|Deltaproteobacteria,2Z2PV@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4154)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4154
SHD3_k127_3243752_0	448385.sce1399	8.875e-316	987.0	COG1629@1|root,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria	1224|Proteobacteria	P	Receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SHD3_k127_3243752_8	926550.CLDAP_06180	3.391e-58	225.0	COG1879@1|root,COG1879@2|Bacteria,2G79U@200795|Chloroflexi	200795|Chloroflexi	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SHD3_k127_3243752_5	1254432.SCE1572_05665	2.741e-79	291.0	COG0643@1|root,COG5000@1|root,COG0643@2|Bacteria,COG5000@2|Bacteria,1R7CN@1224|Proteobacteria,42PXU@68525|delta/epsilon subdivisions,2WMJW@28221|Deltaproteobacteria,2Z2WW@29|Myxococcales	28221|Deltaproteobacteria	NT	Nitrate and nitrite sensing	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	HATPase_c,Hpt,NIT
SHD3_k127_3243752_10	1254432.SCE1572_05675	6.997e-39	148.0	COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,43CTT@68525|delta/epsilon subdivisions,2X81E@28221|Deltaproteobacteria,2Z29Q@29|Myxococcales	28221|Deltaproteobacteria	KT	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
SHD3_k127_3243752_20	1254432.SCE1572_05670	6.654e-05	53.0	COG1406@1|root,COG1406@2|Bacteria	2|Bacteria	N	Chemotaxis phosphatase CheX	cheX-3	-	-	ko:K03409	ko02030,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheX
SHD3_k127_3263712_5	588581.Cpap_0289	5.637e-09	66.0	COG1668@1|root,COG1668@2|Bacteria	2|Bacteria	CP	transmembrane transport	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
SHD3_k127_3263712_3	1536774.H70357_06875	3.937e-83	286.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,4HA8K@91061|Bacilli,26TFZ@186822|Paenibacillaceae	91061|Bacilli	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_3263712_4	511062.GU3_04920	2.386e-76	262.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,1RNUJ@1236|Gammaproteobacteria,1Y4YM@135624|Aeromonadales	135624|Aeromonadales	V	Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides	macB	-	-	ko:K02003,ko:K05685	ko02010,map02010	M00258,M00709	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.122.1,3.A.1.122.12	-	-	ABC_tran,FtsX,MacB_PCD
SHD3_k127_3263712_0	502025.Hoch_0325	6.359e-256	816.0	COG0577@1|root,COG0577@2|Bacteria,1MW6D@1224|Proteobacteria,42PQC@68525|delta/epsilon subdivisions,2WJ8K@28221|Deltaproteobacteria,2YY7H@29|Myxococcales	28221|Deltaproteobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SHD3_k127_3263712_2	1123368.AUIS01000028_gene1325	5.981e-105	360.0	COG0845@1|root,COG0845@2|Bacteria,1PDUT@1224|Proteobacteria,1RQKD@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	HlyD_3,HlyD_D23,OEP
SHD3_k127_3263712_1	404589.Anae109_1076	2.839e-126	416.0	COG3328@1|root,COG3328@2|Bacteria,1MU4P@1224|Proteobacteria,42S30@68525|delta/epsilon subdivisions,2WQ5S@28221|Deltaproteobacteria,2Z141@29|Myxococcales	28221|Deltaproteobacteria	L	transposase mutator type	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SHD3_k127_3266964_3	1254432.SCE1572_09950	4.437e-22	100.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YV97@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SHD3_k127_3266964_0	1313301.AUGC01000001_gene1488	1.849e-179	578.0	COG0442@1|root,COG0442@2|Bacteria,4NEAF@976|Bacteroidetes	976|Bacteroidetes	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
SHD3_k127_3266964_1	1254432.SCE1572_40505	3.65e-106	359.0	COG0628@1|root,COG0628@2|Bacteria,1PTH3@1224|Proteobacteria,42T9W@68525|delta/epsilon subdivisions,2WPRE@28221|Deltaproteobacteria,2YUY8@29|Myxococcales	28221|Deltaproteobacteria	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SHD3_k127_3266964_5	1192034.CAP_7597	2.056e-06	53.0	COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,42M29@68525|delta/epsilon subdivisions,2WJ0X@28221|Deltaproteobacteria,2YU9B@29|Myxococcales	28221|Deltaproteobacteria	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SHD3_k127_3271635_1	391625.PPSIR1_34257	1.669e-42	169.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2Z1F1@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_3271635_2	765869.BDW_03175	1.469e-24	108.0	COG3464@1|root,COG3464@2|Bacteria,1N2KA@1224|Proteobacteria,42WQP@68525|delta/epsilon subdivisions,2MT1Q@213481|Bdellovibrionales,2WRAF@28221|Deltaproteobacteria	213481|Bdellovibrionales	L	COG3464 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
SHD3_k127_3271635_4	1408444.JHYC01000013_gene2473	2.191e-05	47.0	2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales	118969|Legionellales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3271635_0	1192034.CAP_7180	3.591e-82	281.0	COG0169@1|root,COG0169@2|Bacteria,1MVH4@1224|Proteobacteria,42N54@68525|delta/epsilon subdivisions,2WMGU@28221|Deltaproteobacteria,2Z2ZW@29|Myxococcales	28221|Deltaproteobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SHD3_k127_3287771_6	1242864.D187_000504	2.541e-13	80.0	COG0457@1|root,COG0457@2|Bacteria,1PXHP@1224|Proteobacteria,434K6@68525|delta/epsilon subdivisions,2WYXE@28221|Deltaproteobacteria,2Z0V1@29|Myxococcales	28221|Deltaproteobacteria	S	TPR repeat	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16
SHD3_k127_3287771_3	448385.sce2559	3.044e-39	160.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce2559|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3287771_2	1254432.SCE1572_02430	4.639e-43	169.0	COG0632@1|root,COG0632@2|Bacteria,1MWJR@1224|Proteobacteria,42RPS@68525|delta/epsilon subdivisions,2WPH5@28221|Deltaproteobacteria,2Z0ZS@29|Myxococcales	28221|Deltaproteobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
SHD3_k127_3287771_0	1192034.CAP_5847	1.074e-108	364.0	COG1716@1|root,COG1716@2|Bacteria,1Q2GC@1224|Proteobacteria,4382T@68525|delta/epsilon subdivisions,2X0C6@28221|Deltaproteobacteria,2YVG7@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_3287771_1	1254432.SCE1572_02420	3.867e-62	215.0	COG0494@1|root,COG0494@2|Bacteria,1RCZM@1224|Proteobacteria,42T10@68525|delta/epsilon subdivisions,2WPNN@28221|Deltaproteobacteria,2YVNK@29|Myxococcales	28221|Deltaproteobacteria	L	Nudix hydrolase	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX,NUDIX_4
SHD3_k127_3287771_4	448385.sce7288	1.832e-36	147.0	COG1040@1|root,COG1040@2|Bacteria,1RHAV@1224|Proteobacteria,42SV9@68525|delta/epsilon subdivisions,2WPXX@28221|Deltaproteobacteria,2YVCY@29|Myxococcales	28221|Deltaproteobacteria	S	Phosphoribosyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
SHD3_k127_3289551_2	1144275.COCOR_07153	7.673e-13	76.0	COG3391@1|root,COG3391@2|Bacteria,1QX9W@1224|Proteobacteria,43C32@68525|delta/epsilon subdivisions,2X7DQ@28221|Deltaproteobacteria,2YVS2@29|Myxococcales	28221|Deltaproteobacteria	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_3289551_1	1449346.JQMO01000002_gene1303	8.327e-21	107.0	COG0823@1|root,COG0823@2|Bacteria,2IC0F@201174|Actinobacteria,2M4GV@2063|Kitasatospora	201174|Actinobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SHD3_k127_3289551_0	641107.CDLVIII_4239	3.357e-42	173.0	COG5520@1|root,COG5520@2|Bacteria,1U8RG@1239|Firmicutes,248NT@186801|Clostridia,36H0Z@31979|Clostridiaceae	186801|Clostridia	G	dockerin type	xynC1	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_2,CBM_4_9,CBM_6,Dockerin_1,Esterase,Glyco_hydro_30,Glyco_hydro_30C,Polysacc_deac_1,RicinB_lectin_2
SHD3_k127_3290599_3	1254432.SCE1572_14920	5.357e-41	167.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_14920|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3290599_1	448385.sce5315	7.415e-85	304.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_3290599_2	448385.sce6753	2.002e-74	267.0	COG3867@1|root,COG3867@2|Bacteria,1R33X@1224|Proteobacteria	1224|Proteobacteria	G	Arabinogalactan endo-beta-1,4-galactanase	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53
SHD3_k127_3290599_0	498211.CJA_2520	1.222e-137	466.0	COG1022@1|root,COG5184@1|root,COG5276@1|root,COG1022@2|Bacteria,COG5184@2|Bacteria,COG5276@2|Bacteria,1PG4J@1224|Proteobacteria,1RWXR@1236|Gammaproteobacteria,1FIEH@10|Cellvibrio	1236|Gammaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1
SHD3_k127_329087_3	1267535.KB906767_gene3091	1.144e-08	62.0	COG1595@1|root,COG1595@2|Bacteria,3Y815@57723|Acidobacteria	57723|Acidobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_329087_5	1396141.BATP01000058_gene1963	0.0001959	47.0	2EG51@1|root,339WY@2|Bacteria,46WHK@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_329087_4	493475.GARC_2683	8.647e-07	57.0	COG1846@1|root,COG1846@2|Bacteria,1N3J2@1224|Proteobacteria,1S8UY@1236|Gammaproteobacteria,468IT@72275|Alteromonadaceae	1236|Gammaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
SHD3_k127_329087_1	439235.Dalk_4626	2.732e-75	267.0	COG1143@1|root,COG2006@1|root,COG1143@2|Bacteria,COG2006@2|Bacteria,1RABP@1224|Proteobacteria,42QQA@68525|delta/epsilon subdivisions,2WMRX@28221|Deltaproteobacteria,2MK55@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
SHD3_k127_329087_0	246197.MXAN_6138	1.967e-114	369.0	COG0262@1|root,COG0262@2|Bacteria,1QH1Q@1224|Proteobacteria,4341U@68525|delta/epsilon subdivisions,2X4QE@28221|Deltaproteobacteria,2YZE6@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SHD3_k127_3307989_8	1370121.AUWS01000073_gene1010	1.476e-08	65.0	29XQ7@1|root,30JFV@2|Bacteria,2IJJD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3307989_4	1068978.AMETH_2960	5.612e-43	161.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria,4E4JK@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SHD3_k127_3307989_6	1396418.BATQ01000185_gene2128	1.205e-26	117.0	COG2207@1|root,COG2207@2|Bacteria,46X0S@74201|Verrucomicrobia,2IWFJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SHD3_k127_3307989_1	269799.Gmet_3086	1.393e-50	192.0	COG2378@1|root,COG2378@2|Bacteria,1PE00@1224|Proteobacteria,42T67@68525|delta/epsilon subdivisions,2X5N2@28221|Deltaproteobacteria,43SWU@69541|Desulfuromonadales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SHD3_k127_3307989_7	652103.Rpdx1_1005	2.298e-09	64.0	COG1724@1|root,COG1724@2|Bacteria,1NMBX@1224|Proteobacteria	1224|Proteobacteria	N	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SHD3_k127_3307989_2	404589.Anae109_4225	6.826e-50	185.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	BRCT,DUF433,HTH_17,MerR_1,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8
SHD3_k127_3307989_0	388051.AUFE01000042_gene3460	3.281e-144	471.0	COG0468@1|root,COG0468@2|Bacteria,1MU3C@1224|Proteobacteria,2VHNA@28216|Betaproteobacteria,1K09V@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
SHD3_k127_3307989_3	871968.DESME_03075	2.598e-49	202.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SHD3_k127_3307989_5	1192034.CAP_1515	1.153e-34	154.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3327562_8	1297742.A176_04110	1.041e-35	138.0	COG1716@1|root,COG1716@2|Bacteria,1RAA4@1224|Proteobacteria,431UR@68525|delta/epsilon subdivisions,2WWZQ@28221|Deltaproteobacteria,2YU65@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
SHD3_k127_3327562_0	1192034.CAP_0851	1.337e-209	673.0	COG1287@1|root,COG2203@1|root,COG3852@1|root,COG1287@2|Bacteria,COG2203@2|Bacteria,COG3852@2|Bacteria,1MVN6@1224|Proteobacteria,43BPS@68525|delta/epsilon subdivisions,2X710@28221|Deltaproteobacteria,2YU4V@29|Myxococcales	28221|Deltaproteobacteria	T	Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA
SHD3_k127_3327562_1	1297742.A176_05565	3.067e-193	616.0	COG0624@1|root,COG0624@2|Bacteria,1MW20@1224|Proteobacteria,42N09@68525|delta/epsilon subdivisions,2WIRX@28221|Deltaproteobacteria,2YUYT@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
SHD3_k127_3327562_6	1254432.SCE1572_51060	2.037e-46	175.0	COG2264@1|root,COG2264@2|Bacteria	2|Bacteria	J	protein methyltransferase activity	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
SHD3_k127_3327562_5	1192034.CAP_0855	1.36e-55	200.0	COG1057@1|root,COG1057@2|Bacteria,1RD0J@1224|Proteobacteria,42SD9@68525|delta/epsilon subdivisions,2WPPN@28221|Deltaproteobacteria,2YVKY@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3200	CTP_transf_like
SHD3_k127_3327562_3	448385.sce2454	2.022e-75	261.0	COG2386@1|root,COG2386@2|Bacteria,1QF23@1224|Proteobacteria,42RAM@68525|delta/epsilon subdivisions,2WMS1@28221|Deltaproteobacteria,2YVDV@29|Myxococcales	28221|Deltaproteobacteria	U	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes	ccmB	-	-	ko:K02194	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	CcmB
SHD3_k127_3327562_9	1192034.CAP_8687	5.962e-33	134.0	2BUQR@1|root,32Q1U@2|Bacteria,1Q9JK@1224|Proteobacteria,434FE@68525|delta/epsilon subdivisions,2WYSW@28221|Deltaproteobacteria,2Z0IR@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF2505)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2505
SHD3_k127_3327562_10	1192034.CAP_0862	3.538e-29	121.0	29Z2K@1|root,30M04@2|Bacteria,1QAUM@1224|Proteobacteria,43E42@68525|delta/epsilon subdivisions,2WZNA@28221|Deltaproteobacteria,2Z2EY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3327562_2	378806.STAUR_2782	1.006e-77	282.0	COG3863@1|root,COG3863@2|Bacteria,1NCR6@1224|Proteobacteria,42WW5@68525|delta/epsilon subdivisions,2X2EC@28221|Deltaproteobacteria,2YYP2@29|Myxococcales	28221|Deltaproteobacteria	S	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C92
SHD3_k127_3327562_4	290397.Adeh_2597	3.055e-62	218.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2YV5P@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SHD3_k127_3335179_13	765869.BDW_10700	7.389e-17	84.0	COG2730@1|root,COG2730@2|Bacteria,1R8QQ@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_3335179_0	290397.Adeh_3723	5.307e-197	637.0	COG0572@1|root,COG0572@2|Bacteria	2|Bacteria	F	uridine kinase	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
SHD3_k127_3335179_15	7668.SPU_001200-tr	0.0001985	52.0	KOG1217@1|root,KOG1217@2759|Eukaryota	2759|Eukaryota	O	calcium ion binding	-	-	-	-	-	-	-	-	-	-	-	-	EGF,hEGF
SHD3_k127_3335179_11	1254432.SCE1572_33835	4.772e-22	107.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SHD3_k127_3335179_1	1192034.CAP_4442	1.038e-114	388.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_4442|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3335179_3	448385.sce7917	1.501e-89	310.0	COG1388@1|root,COG3770@1|root,COG1388@2|Bacteria,COG3770@2|Bacteria,1MU9I@1224|Proteobacteria,42VK7@68525|delta/epsilon subdivisions,2WS1M@28221|Deltaproteobacteria,2YVMA@29|Myxococcales	28221|Deltaproteobacteria	M	LysM domain protein	mepA	-	-	ko:K07261	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M74
SHD3_k127_3335179_4	1254432.SCE1572_38075	9.237e-82	281.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42T2J@68525|delta/epsilon subdivisions,2WPPV@28221|Deltaproteobacteria,2YXSM@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SHD3_k127_3335179_7	246197.MXAN_3733	1.831e-57	210.0	COG3781@1|root,COG3781@2|Bacteria,1MX91@1224|Proteobacteria,43821@68525|delta/epsilon subdivisions,2X3C3@28221|Deltaproteobacteria,2YVCA@29|Myxococcales	28221|Deltaproteobacteria	S	Bestrophin, RFP-TM, chloride channel	-	-	-	ko:K08994	-	-	-	-	ko00000,ko02000	1.A.46.2	-	-	Bestrophin
SHD3_k127_3335179_14	1123242.JH636436_gene227	2.905e-05	52.0	COG2331@1|root,COG2331@2|Bacteria,2J0RB@203682|Planctomycetes	203682|Planctomycetes	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3335179_10	1167006.UWK_02146	1.181e-25	120.0	COG0746@1|root,COG0746@2|Bacteria,1RKCH@1224|Proteobacteria	1224|Proteobacteria	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	mobA	-	2.7.7.77	ko:K03752	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3,ThiS
SHD3_k127_3335179_12	1304883.KI912532_gene2942	1.3e-17	95.0	COG1763@1|root,COG1763@2|Bacteria,1RD3Q@1224|Proteobacteria,2VSIP@28216|Betaproteobacteria,2KWDE@206389|Rhodocyclales	206389|Rhodocyclales	H	molybdopterin-guanine dinucleotide biosynthesis protein	-	-	-	ko:K03753	-	-	-	-	ko00000	-	-	-	MobB
SHD3_k127_3335179_5	555079.Toce_0276	2.233e-77	271.0	COG0521@1|root,COG2258@1|root,COG0521@2|Bacteria,COG2258@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,42G8D@68295|Thermoanaerobacterales	186801|Clostridia	H	TIGRFAM molybdenum cofactor synthesis domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
SHD3_k127_3335179_9	517418.Ctha_0863	2.141e-39	154.0	COG0315@1|root,COG0521@1|root,COG0315@2|Bacteria,COG0521@2|Bacteria,1FDMF@1090|Chlorobi	1090|Chlorobi	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoaC
SHD3_k127_3335179_2	1227739.Hsw_4060	4.139e-90	310.0	COG0659@1|root,COG0659@2|Bacteria	2|Bacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	MFS_MOT1
SHD3_k127_3335179_8	765913.ThidrDRAFT_3073	7.289e-56	215.0	COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Mob_synth_C,Radical_SAM
SHD3_k127_3335179_6	382464.ABSI01000011_gene3134	5.926e-64	235.0	COG0303@1|root,COG0303@2|Bacteria,46SZB@74201|Verrucomicrobia,2IUKH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	MoeA N-terminal region (domain I and II)	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
SHD3_k127_3339687_1	1283300.ATXB01000001_gene2098	5.898e-107	360.0	COG1449@1|root,COG1449@2|Bacteria,1R5KI@1224|Proteobacteria,1S0ID@1236|Gammaproteobacteria,1XGAT@135618|Methylococcales	135618|Methylococcales	G	Glycosyl hydrolase family 57	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
SHD3_k127_3339687_2	1479239.JQMU01000001_gene702	1.982e-15	88.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,2TR60@28211|Alphaproteobacteria,2K1XQ@204457|Sphingomonadales	204457|Sphingomonadales	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SHD3_k127_3339687_0	1133850.SHJG_0589	1.716e-109	372.0	COG1020@1|root,COG1020@2|Bacteria,2GP0R@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SHD3_k127_3339687_3	575540.Isop_1081	5.393e-09	64.0	COG0236@1|root,COG0236@2|Bacteria,2J1MP@203682|Planctomycetes	203682|Planctomycetes	IQ	acyl carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SHD3_k127_3344624_0	448385.sce6933	7.445e-64	226.0	COG0196@1|root,COG0196@2|Bacteria,1MV9I@1224|Proteobacteria,42MV7@68525|delta/epsilon subdivisions,2WJTU@28221|Deltaproteobacteria,2YV5E@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
SHD3_k127_3353426_1	290397.Adeh_1020	1.826e-83	281.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
SHD3_k127_3353426_2	868131.MSWAN_2214	9.811e-69	245.0	COG2513@1|root,arCOG00581@2157|Archaea,2Y86J@28890|Euryarchaeota	28890|Euryarchaeota	G	COG2513 PEP phosphonomutase and related enzymes	-	-	4.1.3.30,5.4.2.9	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	-	R00409,R00661	RC00286,RC00287,RC02792	ko00000,ko00001,ko01000	-	-	-	PEP_mutase
SHD3_k127_3353426_0	1254432.SCE1572_02475	1.087e-110	373.0	COG4552@1|root,COG4552@2|Bacteria,1NBTH@1224|Proteobacteria,42W5G@68525|delta/epsilon subdivisions,2WXK2@28221|Deltaproteobacteria,2YW0Z@29|Myxococcales	28221|Deltaproteobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
SHD3_k127_3353426_5	2903.EOD23445	0.0001627	53.0	2EMZ8@1|root,2SRHU@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3353426_4	521674.Plim_2230	4.334e-15	87.0	2ESRG@1|root,34C3P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3353426_3	1408422.JHYF01000004_gene1725	1.649e-18	90.0	COG5504@1|root,COG5504@2|Bacteria,1TT7P@1239|Firmicutes,24C0E@186801|Clostridia,36HC5@31979|Clostridiaceae	186801|Clostridia	O	Predicted Zn-dependent protease (DUF2268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2268
SHD3_k127_3356613_1	1121930.AQXG01000004_gene2995	1.474e-85	301.0	COG3534@1|root,COG3534@2|Bacteria,4P2GD@976|Bacteroidetes,1IZ5X@117747|Sphingobacteriia	976|Bacteroidetes	G	alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3356613_2	1121346.KB899821_gene2714	4.85e-62	226.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,4H9MA@91061|Bacilli,26QSG@186822|Paenibacillaceae	91061|Bacilli	I	3-hydroxyisobutyrate dehydrogenase	hopR	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2,PilZ
SHD3_k127_3356613_0	378806.STAUR_7238	8.39e-107	370.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_3363336_2	1123368.AUIS01000005_gene352	9.987e-42	164.0	COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,2NC2J@225057|Acidithiobacillales	225057|Acidithiobacillales	C	Apoptosis-inducing factor, mitochondrion-associated, C-term	-	-	-	-	-	-	-	-	-	-	-	-	AIF_C,Pyr_redox_2
SHD3_k127_3363336_1	926550.CLDAP_02280	7.444e-58	208.0	COG3404@1|root,COG3404@2|Bacteria,2G70J@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Formiminotransferase-cyclodeaminase	-	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
SHD3_k127_3363336_3	1123242.JH636435_gene2375	8.408e-13	81.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,2IXUG@203682|Planctomycetes	203682|Planctomycetes	CP	COG1668 ABC-type Na efflux pump, permease component	-	-	-	ko:K01992,ko:K09696	ko02010,ko02020,map02010,map02020	M00253,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.115	-	-	ABC2_membrane_2,Abi
SHD3_k127_3363336_0	370438.PTH_1002	4.593e-66	235.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,260DA@186807|Peptococcaceae	186801|Clostridia	C	PFAM 2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SHD3_k127_336379_6	554065.XP_005847752.1	1.058e-42	165.0	COG1752@1|root,2SMEN@2759|Eukaryota,37Y6Y@33090|Viridiplantae,34KDX@3041|Chlorophyta	3041|Chlorophyta	I	Lipolytic acyl hydrolase (LAH)	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
SHD3_k127_336379_0	448385.sce1797	1.08e-180	587.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,433ZY@68525|delta/epsilon subdivisions,2X4BJ@28221|Deltaproteobacteria,2Z0YV@29|Myxococcales	28221|Deltaproteobacteria	M	Spore coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
SHD3_k127_336379_8	335543.Sfum_0272	2.403e-19	99.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42V72@68525|delta/epsilon subdivisions,2WRHE@28221|Deltaproteobacteria,2MSA6@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_336379_4	1297742.A176_07580	8.612e-83	295.0	COG4249@1|root,COG4249@2|Bacteria	2|Bacteria	S	B-1 B cell differentiation	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	GUN4,GUN4_N,Peptidase_C13,Peptidase_C14
SHD3_k127_336379_2	448385.sce4185	1.178e-117	414.0	COG5184@1|root,COG5184@2|Bacteria,1PEJQ@1224|Proteobacteria,439SY@68525|delta/epsilon subdivisions,2X560@28221|Deltaproteobacteria,2Z05W@29|Myxococcales	28221|Deltaproteobacteria	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_336379_11	285514.JNWO01000047_gene965	5.028e-08	64.0	COG3325@1|root,COG3469@1|root,COG3325@2|Bacteria,COG3469@2|Bacteria,2GJTU@201174|Actinobacteria	201174|Actinobacteria	G	alpha-galactosidase	-	-	3.2.1.14,3.2.1.4	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	-	R01206,R02334,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH18,GH5,GH9	-	CBM_2,CBM_4_9,Calx-beta,Cellulase,Glyco_hydro_18,PE,fn3
SHD3_k127_336379_7	404589.Anae109_2762	4.866e-30	133.0	COG0484@1|root,COG0484@2|Bacteria	404589.Anae109_2762|-	O	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_336379_3	502025.Hoch_5161	1.78e-96	345.0	COG0484@1|root,COG0484@2|Bacteria,1MXM9@1224|Proteobacteria,4397N@68525|delta/epsilon subdivisions,2X4EI@28221|Deltaproteobacteria,2YYVA@29|Myxococcales	1224|Proteobacteria	C	heat shock protein binding	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrom_c3_2,Cytochrome_C7
SHD3_k127_336379_5	290397.Adeh_2667	1.948e-71	273.0	COG0492@1|root,COG1145@1|root,COG0492@2|Bacteria,COG1145@2|Bacteria,1NDW6@1224|Proteobacteria,42MUD@68525|delta/epsilon subdivisions,2WKZ9@28221|Deltaproteobacteria,2YYPV@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Pyr_redox_3
SHD3_k127_336379_10	96561.Dole_0589	7.056e-11	73.0	COG1145@1|root,COG2006@1|root,COG1145@2|Bacteria,COG2006@2|Bacteria,1RABP@1224|Proteobacteria,42QQA@68525|delta/epsilon subdivisions,2WMRX@28221|Deltaproteobacteria,2MK55@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
SHD3_k127_33680_2	1254432.SCE1572_26650	4.289e-29	131.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Rhs family	-	-	-	-	-	-	-	-	-	-	-	-	AHH,RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
SHD3_k127_33680_1	1254432.SCE1572_51540	1.347e-37	157.0	COG3209@1|root,COG3209@2|Bacteria,1MVV1@1224|Proteobacteria,42P9N@68525|delta/epsilon subdivisions,2WJSQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Rhs family	-	-	-	-	-	-	-	-	-	-	-	-	AHH,RHS_repeat,SpvB,TcdB_toxin_midN,VCBS
SHD3_k127_33680_0	1121920.AUAU01000018_gene1825	3.122e-185	602.0	COG0514@1|root,COG0514@2|Bacteria,3Y2KM@57723|Acidobacteria	57723|Acidobacteria	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RecQ_Zn_bind
SHD3_k127_33680_3	1123508.JH636453_gene5808	2.385e-06	61.0	COG2931@1|root,COG3391@1|root,COG2931@2|Bacteria,COG3391@2|Bacteria,2J08H@203682|Planctomycetes	203682|Planctomycetes	J	Integrin alpha (beta-propellor repeats).	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SHD3_k127_337323_5	96561.Dole_2799	2.739e-68	243.0	COG2267@1|root,COG2267@2|Bacteria,1MWF5@1224|Proteobacteria,42T8M@68525|delta/epsilon subdivisions,2WPBS@28221|Deltaproteobacteria,2MKKR@213118|Desulfobacterales	28221|Deltaproteobacteria	I	Alpha beta hydrolase	agmH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
SHD3_k127_337323_9	1121904.ARBP01000001_gene5866	1.18e-43	172.0	2CA0C@1|root,30S8C@2|Bacteria	2|Bacteria	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
SHD3_k127_337323_6	448385.sce2449	1.238e-63	229.0	COG0741@1|root,COG0741@2|Bacteria,1MZ4X@1224|Proteobacteria,42TVX@68525|delta/epsilon subdivisions,2WP4F@28221|Deltaproteobacteria,2YV7H@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF4124,SLT
SHD3_k127_337323_2	448385.sce2447	1.86e-143	464.0	COG2378@1|root,COG2378@2|Bacteria,1RBK8@1224|Proteobacteria,42R5D@68525|delta/epsilon subdivisions,2WN2E@28221|Deltaproteobacteria,2Z2CD@29|Myxococcales	28221|Deltaproteobacteria	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
SHD3_k127_337323_1	1254432.SCE1572_14685	8.606e-149	482.0	COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,42PCD@68525|delta/epsilon subdivisions,2WKGQ@28221|Deltaproteobacteria,2YU9M@29|Myxococcales	28221|Deltaproteobacteria	F	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis	pdp	-	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
SHD3_k127_337323_0	1123242.JH636434_gene5524	5.093e-300	934.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,2IXD4@203682|Planctomycetes	203682|Planctomycetes	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
SHD3_k127_337323_10	1242864.D187_003438	5.809e-22	101.0	COG5544@1|root,COG5544@2|Bacteria,1PD2E@1224|Proteobacteria,435E0@68525|delta/epsilon subdivisions,2WZRI@28221|Deltaproteobacteria,2Z2KM@29|Myxococcales	28221|Deltaproteobacteria	S	Lipoprotein	-	-	-	ko:K05811	-	-	-	-	ko00000	-	-	-	-
SHD3_k127_337323_4	1254432.SCE1572_17640	2.165e-71	251.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,42Q8V@68525|delta/epsilon subdivisions,2WJP0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_337323_3	1192034.CAP_0155	6.222e-92	326.0	COG0810@1|root,COG0810@2|Bacteria,1QGPT@1224|Proteobacteria,434QY@68525|delta/epsilon subdivisions,2WZ24@28221|Deltaproteobacteria,2Z15Z@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_337323_8	378806.STAUR_3559	9.918e-45	178.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.133,2.5.1.39,2.5.1.42,2.5.1.62	ko:K03179,ko:K04040,ko:K17105	ko00130,ko00564,ko00860,ko01100,ko01110,map00130,map00564,map00860,map01100,map01110	M00117	R04520,R05000,R05615,R06284,R09067,R11514,R11517	RC00020,RC00209,RC01171,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
SHD3_k127_337323_7	443143.GM18_2768	1.422e-58	220.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,42X93@68525|delta/epsilon subdivisions,2WSXR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SHD3_k127_337323_11	926692.AZYG01000007_gene1228	3.457e-14	78.0	COG0419@1|root,COG1196@1|root,COG0419@2|Bacteria,COG1196@2|Bacteria,1V9TU@1239|Firmicutes,24Q7A@186801|Clostridia	186801|Clostridia	L	nuclear chromosome segregation	-	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23
SHD3_k127_3380146_6	383372.Rcas_0264	1.145e-30	123.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3380146_5	215803.DB30_2315	4.52e-50	202.0	COG1520@1|root,COG3055@1|root,COG4676@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,COG4676@2|Bacteria,1NZI5@1224|Proteobacteria,43AH4@68525|delta/epsilon subdivisions,2X5X4@28221|Deltaproteobacteria,2Z37E@29|Myxococcales	1224|Proteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1,Kelch_4,PKD,UPF0560
SHD3_k127_3380146_7	1507.HMPREF0262_01622	1.652e-20	94.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,36DPZ@31979|Clostridiaceae	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
SHD3_k127_3380146_0	502025.Hoch_3647	1.291e-163	522.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_3380146_8	59374.Fisuc_0830	2.244e-13	76.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PA,PPC,Peptidase_M36,Peptidase_S8,SLH
SHD3_k127_3380146_10	926550.CLDAP_34780	3.498e-06	60.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4114,HemolysinCabind,PPC,Peptidase_M8,Peptidase_S8,SLH
SHD3_k127_3380146_4	448385.sce1797	5.121e-55	212.0	COG5337@1|root,COG5337@2|Bacteria,1QCJ4@1224|Proteobacteria,433ZY@68525|delta/epsilon subdivisions,2X4BJ@28221|Deltaproteobacteria,2Z0YV@29|Myxococcales	28221|Deltaproteobacteria	M	Spore coat	-	-	-	-	-	-	-	-	-	-	-	-	CotH
SHD3_k127_3380146_3	463191.SSEG_06046	3.021e-59	222.0	COG1073@1|root,COG5297@1|root,COG1073@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,ArabFuran-catal,RicinB_lectin_2
SHD3_k127_3380146_1	287986.DV20_37225	6.979e-122	406.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria,4E1D9@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	ArabFuran-catal,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_3380146_2	694427.Palpr_2366	1.506e-67	244.0	COG5520@1|root,COG5520@2|Bacteria,4NKP9@976|Bacteroidetes,2FQP9@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 30 family	xynC_2	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_cc
SHD3_k127_3391187_5	483219.LILAB_00515	5.465e-133	434.0	COG4641@1|root,COG4641@2|Bacteria,1MY6E@1224|Proteobacteria,42YKD@68525|delta/epsilon subdivisions,2WU5I@28221|Deltaproteobacteria,2YUP6@29|Myxococcales	28221|Deltaproteobacteria	S	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_2
SHD3_k127_3391187_12	1125863.JAFN01000001_gene1528	8.562e-10	68.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WKJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_3391187_7	1121943.KB899992_gene2160	1.051e-68	244.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	-	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku,Rho_N
SHD3_k127_3391187_8	1121943.KB899992_gene2159	1.918e-67	239.0	COG1273@1|root,COG1273@2|Bacteria,1N4UX@1224|Proteobacteria,1RNJ7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD	ku	-	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
SHD3_k127_3391187_3	1232410.KI421413_gene952	4.325e-262	833.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,1MVWY@1224|Proteobacteria,4378Y@68525|delta/epsilon subdivisions,2X2C1@28221|Deltaproteobacteria,43UD2@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	ATP dependent DNA ligase C terminal region	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
SHD3_k127_3391187_0	448385.sce2118	0.0	1386.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,42M5I@68525|delta/epsilon subdivisions,2WK8Y@28221|Deltaproteobacteria,2YUG8@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,FAD-oxidase_C,FAD_binding_4,Fer4_8
SHD3_k127_3391187_9	266117.Rxyl_2717	3.19e-50	182.0	COG4288@1|root,COG4288@2|Bacteria,2IT13@201174|Actinobacteria,4CT9V@84995|Rubrobacteria	84995|Rubrobacteria	S	Anabaena sensory rhodopsin transducer	-	-	-	-	-	-	-	-	-	-	-	-	ASRT
SHD3_k127_3391187_2	574966.KB898646_gene3486	6.181e-265	827.0	COG0028@1|root,COG0028@2|Bacteria,1MU6U@1224|Proteobacteria,1RMQQ@1236|Gammaproteobacteria,1XHV2@135619|Oceanospirillales	135619|Oceanospirillales	E	acetolactate synthase	-	-	1.2.5.1	ko:K00156	ko00620,map00620	-	R03145	RC00860	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SHD3_k127_3391187_4	448385.sce2119	1.611e-145	469.0	COG4948@1|root,COG4948@2|Bacteria,1MYZE@1224|Proteobacteria,42MY9@68525|delta/epsilon subdivisions,2WKS9@28221|Deltaproteobacteria,2YUFM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the mandelate racemase muconate lactonizing enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SHD3_k127_3391187_11	882378.RBRH_03068	7.392e-18	88.0	2B7KW@1|root,320RZ@2|Bacteria,1RJSP@1224|Proteobacteria,2VTD1@28216|Betaproteobacteria,1K1DA@119060|Burkholderiaceae	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3391187_1	1163617.SCD_n00704	0.0	1237.0	COG3957@1|root,COG3957@2|Bacteria,1MVSE@1224|Proteobacteria,2VIGM@28216|Betaproteobacteria	28216|Betaproteobacteria	G	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
SHD3_k127_3391187_6	290397.Adeh_3183	1.944e-117	398.0	2DPRW@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,3334N@2|Bacteria,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
SHD3_k127_3393351_12	1192034.CAP_5302	6.524e-13	72.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SHD3_k127_3393351_9	448385.sce4273	4.104e-27	118.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02456	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	N_methyl,T2SSG
SHD3_k127_3393351_7	448385.sce4274	5.502e-42	161.0	COG4969@1|root,COG4969@2|Bacteria,1R0CQ@1224|Proteobacteria,43CV8@68525|delta/epsilon subdivisions,2X835@28221|Deltaproteobacteria,2Z3JW@29|Myxococcales	28221|Deltaproteobacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl
SHD3_k127_3393351_8	448385.sce4276	3.766e-33	137.0	COG4969@1|root,COG4969@2|Bacteria,1QWD5@1224|Proteobacteria	1224|Proteobacteria	NU	Belongs to the N-Me-Phe pilin family	-	-	-	ko:K02650	ko02020,map02020	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.15.2	-	-	N_methyl,Pilin
SHD3_k127_3393351_4	1254432.SCE1572_25865	1.747e-77	269.0	COG0457@1|root,COG0457@2|Bacteria,1NMQD@1224|Proteobacteria,42XCX@68525|delta/epsilon subdivisions,2WSK3@28221|Deltaproteobacteria,2Z31X@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3393351_0	448385.sce4279	3.912e-224	729.0	2C4HX@1|root,2Z9XP@2|Bacteria,1MY22@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3393351_1	1192034.CAP_5305	8.545e-170	545.0	COG0621@1|root,COG0621@2|Bacteria,1MU7N@1224|Proteobacteria,42MRJ@68525|delta/epsilon subdivisions,2WITA@28221|Deltaproteobacteria,2YUDC@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
SHD3_k127_3393351_10	204669.Acid345_2150	5.065e-22	103.0	2DMJE@1|root,32RYR@2|Bacteria,3Y4XN@57723|Acidobacteria,2JJFS@204432|Acidobacteriia	204432|Acidobacteriia	S	Domain of unknown function (DUF4112)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4112
SHD3_k127_3393351_13	1448389.BAVQ01000043_gene1922	1.306e-06	61.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_3393351_3	357808.RoseRS_4055	1.661e-133	436.0	COG0505@1|root,COG0505@2|Bacteria,2G5S1@200795|Chloroflexi,3755X@32061|Chloroflexia	32061|Chloroflexia	F	TIGRFAM carbamoyl-phosphate synthase, small subunit	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
SHD3_k127_3393351_2	1192034.CAP_5306	1.518e-158	530.0	COG0044@1|root,COG0044@2|Bacteria,1MVXY@1224|Proteobacteria,42MJ9@68525|delta/epsilon subdivisions,2WJH8@28221|Deltaproteobacteria,2YU2Z@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
SHD3_k127_3393351_5	502025.Hoch_4573	2.111e-75	291.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_6,TPR_7,TPR_8
SHD3_k127_3395440_4	1242864.D187_000272	4.937e-51	196.0	COG0644@1|root,COG0644@2|Bacteria,1PFC1@1224|Proteobacteria,42VN7@68525|delta/epsilon subdivisions,2WR8D@28221|Deltaproteobacteria,2Z2KV@29|Myxococcales	28221|Deltaproteobacteria	C	FAD binding domain	-	-	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
SHD3_k127_3395440_3	365046.Rta_23850	2.924e-51	185.0	COG4119@1|root,COG4119@2|Bacteria,1RHCE@1224|Proteobacteria,2VV6B@28216|Betaproteobacteria	28216|Betaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SHD3_k127_3395440_5	1242864.D187_008639	9.45e-49	183.0	COG1633@1|root,COG1633@2|Bacteria,1PR5N@1224|Proteobacteria,437AS@68525|delta/epsilon subdivisions,2X2F3@28221|Deltaproteobacteria,2Z1A4@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
SHD3_k127_3395440_0	886293.Sinac_0738	1.016e-237	751.0	COG3387@1|root,COG3387@2|Bacteria,2IXUW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 15	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
SHD3_k127_3395440_7	448385.sce8139	1.886e-27	121.0	COG5592@1|root,COG5592@2|Bacteria,1ND3D@1224|Proteobacteria,42WES@68525|delta/epsilon subdivisions,2WSA6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SHD3_k127_3395440_6	483219.LILAB_19405	1.126e-34	139.0	COG1633@1|root,COG1633@2|Bacteria,1QX6R@1224|Proteobacteria,432ES@68525|delta/epsilon subdivisions,2WYEY@28221|Deltaproteobacteria,2Z3EJ@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF2383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
SHD3_k127_3395440_2	1192034.CAP_8932	7.236e-56	200.0	COG3861@1|root,COG3861@2|Bacteria,1QE0P@1224|Proteobacteria,42TDZ@68525|delta/epsilon subdivisions,2WPW5@28221|Deltaproteobacteria,2Z2TG@29|Myxococcales	28221|Deltaproteobacteria	S	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3395440_1	1123371.ATXH01000009_gene1077	1.519e-116	383.0	COG0438@1|root,COG0438@2|Bacteria,2GHNP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_3419655_1	448385.sce2236	1.431e-76	278.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	asgD	-	3.1.3.3	ko:K07315	-	-	-	-	ko00000,ko01000,ko03021	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SHD3_k127_3419655_0	1254432.SCE1572_03510	0.0	1043.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,430UT@68525|delta/epsilon subdivisions,2X6PU@28221|Deltaproteobacteria,2Z3C4@29|Myxococcales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF5110)	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
SHD3_k127_3425766_5	1192034.CAP_8625	1.328e-60	216.0	29XG8@1|root,30J6Q@2|Bacteria,1R0D3@1224|Proteobacteria,43CVQ@68525|delta/epsilon subdivisions,2X83Q@28221|Deltaproteobacteria,2YW3E@29|Myxococcales	28221|Deltaproteobacteria	S	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SHD3_k127_3425766_2	452637.Oter_3478	1.665e-191	604.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,3K7PK@414999|Opitutae	74201|Verrucomicrobia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
SHD3_k127_3425766_7	886293.Sinac_0455	1.372e-10	68.0	COG0858@1|root,COG0858@2|Bacteria,2J19A@203682|Planctomycetes	203682|Planctomycetes	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3425766_4	338966.Ppro_0477	4.364e-127	424.0	COG1143@1|root,COG1143@2|Bacteria,1QYG4@1224|Proteobacteria,43E88@68525|delta/epsilon subdivisions,2X7N9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3425766_1	530564.Psta_3194	2.834e-269	845.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2IYK8@203682|Planctomycetes	203682|Planctomycetes	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
SHD3_k127_3425766_0	240015.ACP_1268	4.645e-305	965.0	2CDRA@1|root,2Z7QN@2|Bacteria,3Y73N@57723|Acidobacteria,2JMK6@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3425766_3	1242864.D187_010311	2.094e-191	606.0	COG0663@1|root,COG0663@2|Bacteria,1Q0SI@1224|Proteobacteria,439EX@68525|delta/epsilon subdivisions,2X4Q4@28221|Deltaproteobacteria,2YZDQ@29|Myxococcales	28221|Deltaproteobacteria	S	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3433899_8	1345695.CLSA_c09200	1.366e-15	88.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,36GBY@31979|Clostridiaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SHD3_k127_3433899_2	502025.Hoch_4238	4.617e-49	195.0	COG1109@1|root,COG1482@1|root,COG1109@2|Bacteria,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,42QR1@68525|delta/epsilon subdivisions,2WU24@28221|Deltaproteobacteria,2YUXK@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphomannose isomerase type I	-	-	5.3.1.8,5.4.2.8	ko:K01809,ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818,R01819	RC00376,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
SHD3_k127_3433899_1	246197.MXAN_5476	1.735e-95	353.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,4383V@68525|delta/epsilon subdivisions,2X0HP@28221|Deltaproteobacteria,2YVM9@29|Myxococcales	28221|Deltaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_3433899_0	1089545.KB913037_gene2605	1.521e-111	378.0	COG4733@1|root,COG4733@2|Bacteria,2HJAB@201174|Actinobacteria,4E5P6@85010|Pseudonocardiales	201174|Actinobacteria	S	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_6
SHD3_k127_3433899_10	204669.Acid345_2637	3.419e-11	66.0	COG2161@1|root,COG2161@2|Bacteria,3Y5VX@57723|Acidobacteria,2JK4M@204432|Acidobacteriia	204432|Acidobacteriia	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SHD3_k127_3433899_9	1031288.AXAA01000046_gene2146	2.122e-15	82.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,36GBY@31979|Clostridiaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SHD3_k127_3433899_3	794903.OPIT5_19320	1.396e-34	138.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Mut7-C
SHD3_k127_3433899_7	794903.OPIT5_19315	3.424e-24	105.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
SHD3_k127_3433899_11	331678.Cphamn1_1346	0.0006963	48.0	COG0433@1|root,COG0433@2|Bacteria,1FEIF@1090|Chlorobi	1090|Chlorobi	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF87
SHD3_k127_3433899_5	1395587.P364_0108775	5.884e-32	140.0	COG5464@1|root,COG5464@2|Bacteria,1V1A7@1239|Firmicutes,4HG0B@91061|Bacilli,26SWZ@186822|Paenibacillaceae	91061|Bacilli	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SHD3_k127_3433899_6	1345695.CLSA_c09200	6.779e-32	136.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,36GBY@31979|Clostridiaceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
SHD3_k127_3442293_2	1254432.SCE1572_14350	8.629e-39	149.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2Z2XY@29|Myxococcales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SHD3_k127_3442293_3	1254432.SCE1572_03950	3.828e-21	102.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria	1224|Proteobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.57	ko:K13779,ko:K15312	ko00281,map00281	-	R03493	RC00941	ko00000,ko00001,ko01000,ko01008	-	-	-	ECH_1
SHD3_k127_3442293_4	1167006.UWK_01756	7.5e-12	73.0	COG1908@1|root,COG1908@2|Bacteria,1MZ7V@1224|Proteobacteria,42UHS@68525|delta/epsilon subdivisions,2WQMX@28221|Deltaproteobacteria,2MQ23@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM methyl-viologen-reducing hydrogenase delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
SHD3_k127_3442293_1	555088.DealDRAFT_1099	6.882e-49	186.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,42K7P@68298|Syntrophomonadaceae	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SHD3_k127_3442293_0	880072.Desac_1037	1.34e-80	282.0	COG1304@1|root,COG2221@1|root,COG1304@2|Bacteria,COG2221@2|Bacteria	2|Bacteria	C	Nitrite and sulphite reductase 4Fe-4S	yahG	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_1033	DUF1116,FMN_dh,Fer4,Glu_synthase
SHD3_k127_3444429_1	391625.PPSIR1_11130	2.633e-51	197.0	COG1262@1|root,COG1262@2|Bacteria,1QADB@1224|Proteobacteria,43503@68525|delta/epsilon subdivisions,2X93Q@28221|Deltaproteobacteria,2Z1R3@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_3444429_0	1254432.SCE1572_07785	8.259e-72	254.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2Z073@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_3444429_2	398512.JQKC01000029_gene4335	3.517e-44	174.0	COG2755@1|root,COG2755@2|Bacteria,1TSSA@1239|Firmicutes,24EZX@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_3447650_1	1254432.SCE1572_51110	3.06e-133	443.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,42MCN@68525|delta/epsilon subdivisions,2WIYA@28221|Deltaproteobacteria,2YUYF@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	ntrY	-	2.7.13.3	ko:K13598	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4
SHD3_k127_3447650_5	1254432.SCE1572_51115	1.115e-84	291.0	COG0840@1|root,COG0840@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SHD3_k127_3447650_4	1254432.SCE1572_51115	6.958e-95	315.0	COG0840@1|root,COG0840@2|Bacteria,1RG2B@1224|Proteobacteria,42RYX@68525|delta/epsilon subdivisions,2WNHC@28221|Deltaproteobacteria,2YU4H@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	rppA	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal
SHD3_k127_3447650_2	1254432.SCE1572_10755	2.101e-117	396.0	COG1305@1|root,COG1305@2|Bacteria,1R0BY@1224|Proteobacteria,43DTA@68525|delta/epsilon subdivisions,2X8VQ@28221|Deltaproteobacteria,2Z0KI@29|Myxococcales	28221|Deltaproteobacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
SHD3_k127_3447650_7	640081.Dsui_3378	2.075e-10	66.0	2DPTK@1|root,333BS@2|Bacteria,1QVH8@1224|Proteobacteria,2VWD4@28216|Betaproteobacteria,2M02S@206389|Rhodocyclales	206389|Rhodocyclales	S	YXWGXW repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	YXWGXW
SHD3_k127_3447650_8	1192034.CAP_0018	2.901e-10	68.0	29RMJ@1|root,30CQT@2|Bacteria,1QTPA@1224|Proteobacteria,4380Z@68525|delta/epsilon subdivisions,2X3B0@28221|Deltaproteobacteria,2YV6U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3447650_6	469371.Tbis_2951	1.559e-81	281.0	COG0384@1|root,COG0384@2|Bacteria,2GM1W@201174|Actinobacteria,4DZTV@85010|Pseudonocardiales	201174|Actinobacteria	S	Phenazine biosynthesis PhzC PhzF protein	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SHD3_k127_3447650_3	1122605.KB893626_gene2600	4.284e-95	319.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SHD3_k127_3447650_0	316067.Geob_0965	1.136e-177	568.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SHD3_k127_3447998_6	102125.Xen7305DRAFT_00031650	2.381e-66	244.0	2C05R@1|root,2ZCQ7@2|Bacteria	2|Bacteria	S	PFAM Endonuclease Exonuclease phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3447998_9	59374.Fisuc_1992	1.449e-31	136.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K07110,ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,DUF4423,HTH_3,HTH_31,Peptidase_M78
SHD3_k127_3447998_0	1499967.BAYZ01000033_gene1092	1.568e-151	489.0	COG2006@1|root,COG2006@2|Bacteria,2NPTK@2323|unclassified Bacteria	2|Bacteria	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4
SHD3_k127_3447998_5	518766.Rmar_2034	5.018e-93	312.0	COG1028@1|root,COG1028@2|Bacteria,4NKYV@976|Bacteroidetes	976|Bacteroidetes	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SHD3_k127_3447998_8	580340.Tlie_1652	1.082e-42	179.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_76
SHD3_k127_3447998_1	459495.SPLC1_S050840	1.28e-145	472.0	COG0863@1|root,COG0863@2|Bacteria,1G3H1@1117|Cyanobacteria,1H9NU@1150|Oscillatoriales	1117|Cyanobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.113	ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SHD3_k127_3447998_11	309799.DICTH_1607	1.369e-11	66.0	COG2331@1|root,COG2331@2|Bacteria	2|Bacteria	P	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SHD3_k127_3447998_2	448385.sce7890	1.858e-137	454.0	COG0515@1|root,COG0515@2|Bacteria,1PFJ6@1224|Proteobacteria,4340Z@68525|delta/epsilon subdivisions,2X4J2@28221|Deltaproteobacteria,2YZ45@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_3447998_3	448385.sce7670	1.142e-105	359.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,43981@68525|delta/epsilon subdivisions,2X4F4@28221|Deltaproteobacteria,2YYWJ@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SHD3_k127_3447998_10	448385.sce7252	5.224e-27	128.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_3447998_7	448385.sce4032	1.719e-57	216.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_3449134_2	573413.Spirs_0926	3.978e-138	473.0	COG1501@1|root,COG1501@2|Bacteria,2J73G@203691|Spirochaetes	203691|Spirochaetes	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
SHD3_k127_3449134_7	502025.Hoch_1850	4.436e-57	208.0	COG1385@1|root,COG1385@2|Bacteria,1MZBG@1224|Proteobacteria,42R3E@68525|delta/epsilon subdivisions,2WN3C@28221|Deltaproteobacteria,2Z350@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	-	-	-	-	-	-	-	-	-	-	Methyltrans_RNA
SHD3_k127_3449134_1	522306.CAP2UW1_2887	1.699e-286	914.0	COG0587@1|root,COG0587@2|Bacteria,1MUE4@1224|Proteobacteria,2VHCS@28216|Betaproteobacteria,1KR7N@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	-	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SHD3_k127_3449134_4	1192034.CAP_7839	7.713e-97	338.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,4320V@68525|delta/epsilon subdivisions,2WW8U@28221|Deltaproteobacteria,2YW2I@29|Myxococcales	28221|Deltaproteobacteria	L	nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C
SHD3_k127_3449134_9	448385.sce1739	2.517e-45	174.0	COG0468@1|root,COG0468@2|Bacteria,1PBWC@1224|Proteobacteria,433TR@68525|delta/epsilon subdivisions,2X3F6@28221|Deltaproteobacteria,2YVTP@29|Myxococcales	28221|Deltaproteobacteria	L	recA bacterial DNA recombination protein	-	-	-	-	-	-	-	-	-	-	-	-	RecA
SHD3_k127_3449134_13	196490.AUEZ01000052_gene182	1.393e-18	99.0	COG4346@1|root,COG4346@2|Bacteria,1QHX0@1224|Proteobacteria,2TVG5@28211|Alphaproteobacteria,3JT74@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	2.4.1.109	ko:K00728	ko00514,ko00515,ko01100,map00514,map00515,map01100	-	R04072,R07620,R11399	RC00005,RC00059,RC00397	ko00000,ko00001,ko01000,ko01003	-	GT39	-	PMT,PMT_2,PMT_4TMC
SHD3_k127_3449134_5	1242864.D187_000970	1.068e-86	310.0	COG1807@1|root,COG1807@2|Bacteria,1NPGH@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	-
SHD3_k127_3449134_6	391625.PPSIR1_21914	1.931e-86	302.0	COG0515@1|root,COG0515@2|Bacteria	391625.PPSIR1_21914|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3449134_18	1236902.ANAS01000011_gene1451	0.0007077	51.0	COG3209@1|root,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria,4EK62@85012|Streptosporangiales	201174|Actinobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,Laminin_G_3,PT-HINT,RHS_repeat
SHD3_k127_3449134_10	448385.sce5448	3.388e-37	147.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_3449134_3	1254432.SCE1572_34825	1.824e-112	369.0	COG1606@1|root,COG1606@2|Bacteria,1R7UZ@1224|Proteobacteria,42Q6V@68525|delta/epsilon subdivisions,2WKIM@28221|Deltaproteobacteria,2YUUD@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM asparagine synthase	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
SHD3_k127_3449134_0	448385.sce4541	0.0	1032.0	COG1185@1|root,COG1185@2|Bacteria,1MVB9@1224|Proteobacteria,42MTZ@68525|delta/epsilon subdivisions,2WJCE@28221|Deltaproteobacteria,2YUER@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
SHD3_k127_3449134_11	439235.Dalk_4742	2.061e-33	130.0	COG0184@1|root,COG0184@2|Bacteria,1MZ2W@1224|Proteobacteria,42TPZ@68525|delta/epsilon subdivisions,2WQ0P@28221|Deltaproteobacteria,2MKH5@213118|Desulfobacterales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA	rpsO	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
SHD3_k127_3449134_8	631362.Thi970DRAFT_00187	7.796e-47	172.0	COG3577@1|root,COG3577@2|Bacteria,1MYMV@1224|Proteobacteria,1S8C8@1236|Gammaproteobacteria,1WYQ4@135613|Chromatiales	135613|Chromatiales	S	Clan AA aspartic protease, AF_0612 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3449134_12	589865.DaAHT2_0701	5.096e-23	111.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2MIED@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_3451376_4	448385.sce1635	3.83e-160	514.0	COG4591@1|root,COG4591@2|Bacteria,1MVV7@1224|Proteobacteria,42MV0@68525|delta/epsilon subdivisions,2WITK@28221|Deltaproteobacteria,2YUSA@29|Myxococcales	28221|Deltaproteobacteria	M	ABC-type transport system involved in lipoprotein release permease component	lolC	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
SHD3_k127_3451376_7	448385.sce1636	1.2e-106	355.0	COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,42QNS@68525|delta/epsilon subdivisions,2WMSN@28221|Deltaproteobacteria,2YURX@29|Myxococcales	28221|Deltaproteobacteria	V	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner	lolD	-	-	ko:K09810	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.125	-	-	ABC_tran
SHD3_k127_3451376_11	1304885.AUEY01000090_gene2886	7.664e-56	199.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42RB9@68525|delta/epsilon subdivisions,2WMPE@28221|Deltaproteobacteria,2MJPY@213118|Desulfobacterales	28221|Deltaproteobacteria	P	Ferritin-like domain	bfr	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SHD3_k127_3451376_0	448385.sce2923	0.0	1236.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1QA6R@1224|Proteobacteria	2|Bacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SHD3_k127_3451376_5	452637.Oter_1350	3.508e-123	421.0	COG0457@1|root,COG0457@2|Bacteria,46Y0G@74201|Verrucomicrobia,3K8R1@414999|Opitutae	414999|Opitutae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3451376_3	448385.sce2927	1.247e-169	562.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02282,ko:K20971	ko02025,map02025	-	-	-	ko00000,ko00001,ko01001,ko02022,ko02035,ko02044	-	-	-	7TMR-DISMED2,7TMR-DISM_7TM,AAA_31,HATPase_c,HTH_8,HisKA,PAS_7,Response_reg,Sigma54_activ_2,V4R,XylR_N
SHD3_k127_3451376_2	1254432.SCE1572_17590	3.445e-191	606.0	COG1875@1|root,COG1875@2|Bacteria,1MUX1@1224|Proteobacteria,42MK9@68525|delta/epsilon subdivisions,2WJ1C@28221|Deltaproteobacteria,2YY78@29|Myxococcales	28221|Deltaproteobacteria	T	Large family of predicted nucleotide-binding domains	phoH1	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
SHD3_k127_3451376_10	1254432.SCE1572_17595	3.325e-60	223.0	COG3930@1|root,COG3930@2|Bacteria	2|Bacteria	E	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF1704
SHD3_k127_3451376_12	583355.Caka_0358	3.962e-48	186.0	COG1917@1|root,COG4977@1|root,COG1917@2|Bacteria,COG4977@2|Bacteria,46Z91@74201|Verrucomicrobia	74201|Verrucomicrobia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SHD3_k127_3451376_8	1183438.GKIL_1098	2.378e-78	274.0	COG0708@1|root,COG0708@2|Bacteria,1G29X@1117|Cyanobacteria	1117|Cyanobacteria	L	Exodeoxyribonuclease iii	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
SHD3_k127_3451376_1	1254432.SCE1572_19705	7.362e-274	870.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SHD3_k127_3451376_6	448385.sce0378	1.611e-122	413.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42MNA@68525|delta/epsilon subdivisions,2X3SJ@28221|Deltaproteobacteria,2YX0A@29|Myxococcales	28221|Deltaproteobacteria	OU	Signal peptide peptidase	sppA	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SHD3_k127_3451376_16	502025.Hoch_1830	9.38e-20	104.0	COG5640@1|root,COG5640@2|Bacteria,1NNT3@1224|Proteobacteria,4336R@68525|delta/epsilon subdivisions,2WXZ9@28221|Deltaproteobacteria,2YV5V@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SHD3_k127_3451376_13	1121405.dsmv_1931	4.939e-42	164.0	COG3945@1|root,COG3945@2|Bacteria,1RG8J@1224|Proteobacteria,42S6P@68525|delta/epsilon subdivisions,2WNYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SHD3_k127_3451376_9	349521.HCH_04219	5.057e-75	257.0	COG0847@1|root,COG0847@2|Bacteria,1RDF2@1224|Proteobacteria,1S44N@1236|Gammaproteobacteria,1XMCN@135619|Oceanospirillales	135619|Oceanospirillales	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3451376_18	1150398.JIBJ01000004_gene2765	6.326e-13	81.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C,Laminin_G_3,PKD
SHD3_k127_3454426_0	1192034.CAP_5227	2.328e-148	479.0	COG0162@1|root,COG0162@2|Bacteria,1MVUQ@1224|Proteobacteria,42N2A@68525|delta/epsilon subdivisions,2WIP6@28221|Deltaproteobacteria,2YU10@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
SHD3_k127_3454426_6	1121403.AUCV01000008_gene1588	1.808e-40	157.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2MJTK@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM transcription factor CarD	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SHD3_k127_3454426_4	861299.J421_2533	1.057e-44	175.0	COG2096@1|root,COG2096@2|Bacteria,1ZT4I@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
SHD3_k127_3454426_2	448385.sce2574	5.491e-98	340.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42NY2@68525|delta/epsilon subdivisions,2WJKQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF1566,Pkinase
SHD3_k127_3454426_10	448385.sce4032	0.0009931	51.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_3454426_9	661478.OP10G_4340	1.435e-19	93.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K16210	-	-	-	-	ko00000,ko02000	2.A.2.5	-	-	MFS_1,MFS_2,Peripla_BP_3
SHD3_k127_3454426_1	448385.sce3314	5.514e-126	421.0	COG2304@1|root,COG2304@2|Bacteria,1RCMB@1224|Proteobacteria	1224|Proteobacteria	S	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_M64
SHD3_k127_3454426_3	1051632.TPY_2452	6.897e-46	173.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
SHD3_k127_3454426_8	1192034.CAP_2871	1.644e-24	113.0	COG0526@1|root,COG0526@2|Bacteria,1PYQJ@1224|Proteobacteria,435HK@68525|delta/epsilon subdivisions,2WZV8@28221|Deltaproteobacteria,2Z2TQ@29|Myxococcales	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3461254_11	391625.PPSIR1_26658	5.438e-45	177.0	COG0705@1|root,COG0705@2|Bacteria,1MYPM@1224|Proteobacteria	1224|Proteobacteria	S	Rhomboid-type serine protease that catalyzes intramembrane proteolysis	glpG	GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:0140096,GO:1901363,GO:1901564,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141	-	ko:K02441	-	-	-	-	ko00000	-	-	-	NRho,Rhomboid,Rhomboid_N
SHD3_k127_3461254_9	215803.DB30_6914	1.083e-56	205.0	COG4221@1|root,COG4221@2|Bacteria,1PWXN@1224|Proteobacteria,43811@68525|delta/epsilon subdivisions,2X3B3@28221|Deltaproteobacteria,2YV70@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4336)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4336
SHD3_k127_3461254_13	290397.Adeh_0078	7.918e-36	152.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3461254_15	316273.XCV3105	3.022e-26	113.0	2EHW5@1|root,33BMQ@2|Bacteria,1P29Q@1224|Proteobacteria,1T710@1236|Gammaproteobacteria,1X8K7@135614|Xanthomonadales	135614|Xanthomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3461254_8	502025.Hoch_6045	2.488e-60	236.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1Q53R@1224|Proteobacteria,430W1@68525|delta/epsilon subdivisions,2WVP7@28221|Deltaproteobacteria,2YWDG@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
SHD3_k127_3461254_3	395495.Lcho_3088	7.222e-85	297.0	28PW6@1|root,2ZCGK@2|Bacteria,1R61T@1224|Proteobacteria,2VXBE@28216|Betaproteobacteria,1KNHF@119065|unclassified Burkholderiales	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3461254_2	448385.sce5315	1.196e-93	334.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions,2X50D@28221|Deltaproteobacteria,2YZXK@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_3461254_6	880072.Desac_1082	1.671e-68	252.0	COG0620@1|root,COG0620@2|Bacteria,1R6KI@1224|Proteobacteria,42PCN@68525|delta/epsilon subdivisions,2WKT3@28221|Deltaproteobacteria,2MRM1@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3461254_10	456442.Mboo_1191	1.777e-45	174.0	COG3640@1|root,arCOG00587@2157|Archaea,2XT61@28890|Euryarchaeota,2N9QI@224756|Methanomicrobia	224756|Methanomicrobia	D	AAA domain	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
SHD3_k127_3461254_5	756499.Desde_3265	5.843e-69	243.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,260Q5@186807|Peptococcaceae	186801|Clostridia	D	PFAM CobQ CobB MinD ParA nucleotide binding domain	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
SHD3_k127_3461254_1	760568.Desku_2787	3.523e-208	667.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25ZZF@186807|Peptococcaceae	186801|Clostridia	C	TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
SHD3_k127_3461254_14	635013.TherJR_1938	4.04e-31	140.0	COG1142@1|root,COG1142@2|Bacteria,1V809@1239|Firmicutes,25E9V@186801|Clostridia,262AX@186807|Peptococcaceae	186801|Clostridia	C	PFAM 4Fe-4S	-	-	-	ko:K00196	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4
SHD3_k127_3461254_7	768704.Desmer_1789	7.624e-63	237.0	COG1251@1|root,COG1251@2|Bacteria,1TQYX@1239|Firmicutes,24AD5@186801|Clostridia,261IP@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
SHD3_k127_3461254_0	555779.Dthio_PD3239	1.235e-275	871.0	COG1614@1|root,COG1614@2|Bacteria,1MVI5@1224|Proteobacteria,42N9A@68525|delta/epsilon subdivisions,2WK4H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit	-	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
SHD3_k127_3461254_4	264732.Moth_1198	1.011e-78	286.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,42FRG@68295|Thermoanaerobacterales	186801|Clostridia	C	CO dehydrogenase acetyl-CoA synthase	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
SHD3_k127_3461254_12	429009.Adeg_0337	1.972e-39	154.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,42EP5@68295|Thermoanaerobacterales	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
SHD3_k127_3483765_0	1123508.JH636447_gene7938	2.644e-161	545.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4150,PAAR_motif,RHS,RHS_repeat,YwqJ-deaminase
SHD3_k127_3492896_5	1449126.JQKL01000013_gene3402	5.094e-28	115.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA2	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SHD3_k127_3492896_2	448385.sce3766	3.607e-79	284.0	COG0515@1|root,COG0515@2|Bacteria,1PFJ6@1224|Proteobacteria,4340Z@68525|delta/epsilon subdivisions,2X4J2@28221|Deltaproteobacteria,2YZ45@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_3492896_1	926550.CLDAP_33840	5.889e-104	347.0	COG1313@1|root,COG1313@2|Bacteria,2G65I@200795|Chloroflexi	200795|Chloroflexi	C	Radical SAM domain protein	-	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SHD3_k127_3492896_6	702450.CUW_2372	6.81e-16	90.0	COG4552@1|root,COG4552@2|Bacteria,1V86K@1239|Firmicutes	1239|Firmicutes	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
SHD3_k127_3492896_4	404589.Anae109_0839	7.033e-58	216.0	COG1595@1|root,COG1595@2|Bacteria,1MVPD@1224|Proteobacteria,43AKN@68525|delta/epsilon subdivisions,2X60M@28221|Deltaproteobacteria,2Z1JH@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
SHD3_k127_3492896_3	1192034.CAP_7780	2.488e-62	220.0	COG0233@1|root,COG0233@2|Bacteria,1N66T@1224|Proteobacteria,42NAA@68525|delta/epsilon subdivisions,2WNMN@28221|Deltaproteobacteria,2YV1Q@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
SHD3_k127_3492896_0	1254432.SCE1572_37210	1.039e-114	376.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SHD3_k127_3493606_2	754476.Q7A_3010	8.326e-57	203.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,1RR44@1236|Gammaproteobacteria,462AB@72273|Thiotrichales	72273|Thiotrichales	S	Histidine-specific methyltransferase, SAM-dependent	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SHD3_k127_3493606_0	448385.sce6929	7.652e-120	399.0	COG4232@1|root,COG4232@2|Bacteria,1MU8W@1224|Proteobacteria,42MVQ@68525|delta/epsilon subdivisions,2WMS6@28221|Deltaproteobacteria,2Z30T@29|Myxococcales	28221|Deltaproteobacteria	CO	Cytochrome C biogenesis protein transmembrane region	dsbD	-	1.8.1.8	ko:K04084	-	-	-	-	ko00000,ko01000,ko03110	5.A.1.1	-	-	DsbC,DsbD,Thioredoxin_7
SHD3_k127_3493606_1	1254432.SCE1572_40735	4.267e-68	240.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_40735|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3493606_3	1192034.CAP_6891	1.914e-07	53.0	COG1193@1|root,COG1193@2|Bacteria,1NCS6@1224|Proteobacteria,42VGJ@68525|delta/epsilon subdivisions,2WRA6@28221|Deltaproteobacteria,2YVNG@29|Myxococcales	28221|Deltaproteobacteria	L	Smr domain	-	-	-	-	-	-	-	-	-	-	-	-	Smr
SHD3_k127_3498774_18	483219.LILAB_16375	9.871e-59	214.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2YTV2@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
SHD3_k127_3498774_6	448385.sce0564	4.593e-126	418.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,2YZW1@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SHD3_k127_3498774_16	439235.Dalk_2235	2.943e-67	238.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SHD3_k127_3498774_20	1192034.CAP_5498	2.329e-52	191.0	COG5018@1|root,COG5018@2|Bacteria,1RE77@1224|Proteobacteria	1224|Proteobacteria	L	Exonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
SHD3_k127_3498774_0	449447.MAE_19430	1e-323	1010.0	COG1523@1|root,COG1523@2|Bacteria,1G219@1117|Cyanobacteria	1117|Cyanobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SHD3_k127_3498774_4	1499967.BAYZ01000028_gene1265	4.54e-153	494.0	COG1509@1|root,COG1509@2|Bacteria,2NNY6@2323|unclassified Bacteria	2|Bacteria	E	lysine 2,3-aminomutase activity	kamA	-	5.4.3.2	ko:K01843,ko:K19810	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000,ko03012	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
SHD3_k127_3498774_9	1499967.BAYZ01000028_gene1264	1.463e-112	372.0	COG1181@1|root,COG1181@2|Bacteria,2NRF0@2323|unclassified Bacteria	2|Bacteria	M	ATP-grasp domain	ddlA	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SHD3_k127_3498774_24	448385.sce8516	8.563e-16	91.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.55,3.2.1.91	ko:K19668,ko:K20844	ko00500,ko00520,ko01100,ko02020,map00500,map00520,map01100,map02020	-	R01762,R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	CBM42,GH54,GH6	-	ArabFuran-catal,CBM_2,Glyco_hydro_66,RicinB_lectin_2,Ricin_B_lectin,fn3
SHD3_k127_3498774_19	448385.sce8898	1.805e-57	207.0	COG0546@1|root,COG0546@2|Bacteria,1RDDY@1224|Proteobacteria,42T69@68525|delta/epsilon subdivisions,2WNN3@28221|Deltaproteobacteria,2YZCU@29|Myxococcales	28221|Deltaproteobacteria	S	HAD-hyrolase-like	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
SHD3_k127_3498774_23	1121405.dsmv_2367	3.425e-24	117.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SHD3_k127_3498774_22	290397.Adeh_3956	4.326e-29	127.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3498774_8	1192034.CAP_2970	2.169e-115	396.0	COG0790@1|root,COG0790@2|Bacteria,1PFNI@1224|Proteobacteria,4346V@68525|delta/epsilon subdivisions,2X58N@28221|Deltaproteobacteria,2Z09P@29|Myxococcales	28221|Deltaproteobacteria	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
SHD3_k127_3498774_15	1121920.AUAU01000026_gene1445	3.151e-68	238.0	COG3303@1|root,COG3303@2|Bacteria,3Y9EA@57723|Acidobacteria	57723|Acidobacteria	P	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
SHD3_k127_3498774_1	1121920.AUAU01000026_gene1443	1.146e-260	837.0	COG0437@1|root,COG0437@2|Bacteria,3Y2Z0@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
SHD3_k127_3498774_3	903818.KI912268_gene1412	1.064e-212	668.0	COG5557@1|root,COG5557@2|Bacteria,3Y3NS@57723|Acidobacteria	57723|Acidobacteria	C	PFAM Polysulphide reductase, NrfD	-	-	-	-	-	-	-	-	-	-	-	-	NrfD
SHD3_k127_3498774_7	903818.KI912268_gene1411	4.914e-120	401.0	COG2010@1|root,COG2010@2|Bacteria,3Y3HF@57723|Acidobacteria	57723|Acidobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF3341
SHD3_k127_3498774_5	1121920.AUAU01000026_gene1440	8.861e-137	454.0	COG4531@1|root,COG4531@2|Bacteria,3Y2X7@57723|Acidobacteria	57723|Acidobacteria	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3498774_17	903818.KI912268_gene1409	2.835e-62	231.0	COG2010@1|root,COG2010@2|Bacteria,3Y5X3@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,FixO
SHD3_k127_3498774_13	1121920.AUAU01000026_gene1438	2.438e-73	256.0	COG1999@1|root,COG1999@2|Bacteria,3Y3XH@57723|Acidobacteria	57723|Acidobacteria	S	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3498774_2	1121920.AUAU01000026_gene1437	2.043e-240	756.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SHD3_k127_3498774_12	1121920.AUAU01000026_gene1436	2.967e-75	263.0	COG1845@1|root,COG1845@2|Bacteria,3Y414@57723|Acidobacteria	57723|Acidobacteria	C	PFAM cytochrome c oxidase, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	COX3
SHD3_k127_3498774_10	1121920.AUAU01000026_gene1434	5.038e-100	335.0	COG1622@1|root,COG1622@2|Bacteria,3Y2GR@57723|Acidobacteria	57723|Acidobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	-	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C,Cytochrome_CBB3
SHD3_k127_3498774_21	1191523.MROS_0034	2.718e-43	169.0	COG0109@1|root,COG0109@2|Bacteria	2|Bacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
SHD3_k127_3498774_26	1502850.FG91_03726	2.364e-12	79.0	COG0823@1|root,COG0823@2|Bacteria,1MZ1T@1224|Proteobacteria,2UKB8@28211|Alphaproteobacteria,2K99E@204457|Sphingomonadales	204457|Sphingomonadales	U	WD40-like Beta Propeller Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PD40
SHD3_k127_3498774_14	448385.sce5778	3.703e-72	250.0	29XG8@1|root,30J6Q@2|Bacteria,1R0D3@1224|Proteobacteria,43CVQ@68525|delta/epsilon subdivisions,2X83Q@28221|Deltaproteobacteria,2YW3E@29|Myxococcales	28221|Deltaproteobacteria	S	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
SHD3_k127_3499296_4	575540.Isop_0668	7.542e-74	251.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2IY5P@203682|Planctomycetes	203682|Planctomycetes	E	Methionine synthase	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
SHD3_k127_3499296_0	518766.Rmar_0807	1.962e-112	385.0	COG0215@1|root,COG0215@2|Bacteria,4NE3Y@976|Bacteroidetes,1FIUS@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
SHD3_k127_3499296_7	313606.M23134_00497	8.5e-27	121.0	2DFQD@1|root,2ZSNM@2|Bacteria,4P7GE@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3499296_3	1192034.CAP_2808	7.048e-75	267.0	COG4676@1|root,COG4676@2|Bacteria,1Q2DI@1224|Proteobacteria,437ZR@68525|delta/epsilon subdivisions,2X39P@28221|Deltaproteobacteria,2YV0B@29|Myxococcales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3499296_1	1144275.COCOR_07776	9.626e-99	335.0	COG1409@1|root,COG1409@2|Bacteria,1Q1ST@1224|Proteobacteria,437FZ@68525|delta/epsilon subdivisions,2X2NK@28221|Deltaproteobacteria,2YU0N@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SHD3_k127_3499296_5	234267.Acid_0054	8.364e-44	173.0	COG0586@1|root,COG0586@2|Bacteria,3Y364@57723|Acidobacteria	57723|Acidobacteria	S	PFAM SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SHD3_k127_3499296_2	1254432.SCE1572_19705	5.128e-81	287.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SHD3_k127_3501399_1	756499.Desde_1993	1.912e-30	126.0	COG2197@1|root,COG2197@2|Bacteria,1VV36@1239|Firmicutes,2508S@186801|Clostridia,2651R@186807|Peptococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
SHD3_k127_3501399_0	204669.Acid345_2712	2.457e-128	427.0	COG3005@1|root,COG3005@2|Bacteria,3Y3MU@57723|Acidobacteria,2JJ6B@204432|Acidobacteriia	57723|Acidobacteria	C	NapC/NirT cytochrome c family, N-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_NNT
SHD3_k127_3501399_2	1515746.HR45_11315	5.085e-24	117.0	COG3303@1|root,COG3303@2|Bacteria,1NNDS@1224|Proteobacteria	1224|Proteobacteria	C	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3508652_2	1499968.TCA2_1875	5.36e-144	472.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HCT0@91061|Bacilli,27496@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
SHD3_k127_3508652_1	572477.Alvin_1605	2.656e-153	495.0	COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,1WW1E@135613|Chromatiales	135613|Chromatiales	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SHD3_k127_3508652_3	1254432.SCE1572_25175	7.612e-137	447.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YZKE@29|Myxococcales	28221|Deltaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_3508652_9	177437.HRM2_43060	1.28e-28	120.0	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,42U5E@68525|delta/epsilon subdivisions,2WNSN@28221|Deltaproteobacteria,2MJXA@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
SHD3_k127_3508652_10	1192034.CAP_4873	6.986e-22	111.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_4873|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3508652_4	572477.Alvin_2162	5.6e-129	429.0	COG0119@1|root,COG0119@2|Bacteria,1MVQG@1224|Proteobacteria,1RPPW@1236|Gammaproteobacteria,1WW82@135613|Chromatiales	135613|Chromatiales	E	PFAM Pyruvate carboxyltransferase	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
SHD3_k127_3508652_6	448385.sce1764	1.109e-79	275.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SHD3_k127_3508652_0	1254432.SCE1572_44605	2.568e-240	766.0	COG4581@1|root,COG4581@2|Bacteria,1MVD6@1224|Proteobacteria,42PR3@68525|delta/epsilon subdivisions,2X5JT@28221|Deltaproteobacteria,2YU02@29|Myxococcales	28221|Deltaproteobacteria	L	Helicase	mgpS	-	3.6.4.13	ko:K17675	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	Helicase_C
SHD3_k127_3508652_7	96561.Dole_1496	4.46e-71	258.0	COG1902@1|root,COG1902@2|Bacteria,1MVE0@1224|Proteobacteria,42NA7@68525|delta/epsilon subdivisions,2WIN5@28221|Deltaproteobacteria,2MJ30@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
SHD3_k127_3508652_5	448385.sce7993	1.019e-81	282.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_3508652_12	1336245.JAGO01000010_gene898	2.364e-09	64.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1XKQE@135619|Oceanospirillales	135619|Oceanospirillales	P	subunit of a heme lyase	ccmH	-	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
SHD3_k127_3508652_8	85643.Tmz1t_1273	6.15e-47	178.0	COG2716@1|root,COG2716@2|Bacteria,1MZJ6@1224|Proteobacteria,2VRVD@28216|Betaproteobacteria,2KWIM@206389|Rhodocyclales	206389|Rhodocyclales	E	Glycine cleavage system regulatory protein	gcvR	-	-	-	-	-	-	-	-	-	-	-	ACT,ACT_6
SHD3_k127_3508652_11	642492.Clole_0089	8.905e-11	68.0	COG0457@1|root,COG0535@1|root,COG0457@2|Bacteria,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_3512009_3	472759.Nhal_3219	4.743e-56	206.0	COG2303@1|root,COG2303@2|Bacteria,1MXUT@1224|Proteobacteria,1S03P@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	(GMC) oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,GMC_oxred_C,Pyr_redox_2
SHD3_k127_3512009_6	743299.Acife_3113	1.523e-24	112.0	COG4891@1|root,COG4891@2|Bacteria,1N4U1@1224|Proteobacteria,1SG3N@1236|Gammaproteobacteria,2NDRR@225057|Acidithiobacillales	1236|Gammaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
SHD3_k127_3512009_1	1192034.CAP_0705	2.512e-87	305.0	COG3950@1|root,COG3950@2|Bacteria,1PKXP@1224|Proteobacteria,439S9@68525|delta/epsilon subdivisions,2X556@28221|Deltaproteobacteria,2Z04Q@29|Myxococcales	28221|Deltaproteobacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3512009_4	502025.Hoch_3797	7.096e-48	177.0	COG2036@1|root,COG2036@2|Bacteria,1N3S6@1224|Proteobacteria,42UYX@68525|delta/epsilon subdivisions,2WQE4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	B	protein heterodimerization activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3512009_2	448385.sce1239	2.442e-58	211.0	COG0800@1|root,COG0800@2|Bacteria,1MUVJ@1224|Proteobacteria,42RDD@68525|delta/epsilon subdivisions,2X6JS@28221|Deltaproteobacteria,2Z3BH@29|Myxococcales	28221|Deltaproteobacteria	G	KDPG and KHG aldolase	-	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
SHD3_k127_3512009_0	404589.Anae109_4165	9.521e-111	369.0	COG1475@1|root,COG1475@2|Bacteria	2|Bacteria	K	chromosome segregation	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
SHD3_k127_3512009_5	1191523.MROS_2102	2.973e-40	153.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2,MFS_3
SHD3_k127_3524231_4	1340493.JNIF01000003_gene2589	3.82e-13	72.0	COG1131@1|root,COG1131@2|Bacteria,3Y725@57723|Acidobacteria	57723|Acidobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_3524231_1	290397.Adeh_3111	9.462e-67	248.0	COG1566@1|root,COG1566@2|Bacteria,1QU7Z@1224|Proteobacteria,43BPM@68525|delta/epsilon subdivisions,2X70W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM secretion protein HlyD family protein	ybhG	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SHD3_k127_3524231_2	378806.STAUR_0773	1.937e-60	227.0	COG4191@1|root,COG4191@2|Bacteria,1QXD8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_8,Response_reg,SBP_bac_3
SHD3_k127_3524231_0	404589.Anae109_0889	1.979e-164	529.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07713	ko02020,map02020	M00499	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_3524231_3	469596.HMPREF9488_02451	2.133e-19	94.0	COG4859@1|root,COG4859@2|Bacteria,1VB1S@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3529137_2	382464.ABSI01000005_gene1378	8.908e-29	129.0	COG1262@1|root,COG1262@2|Bacteria,46WEI@74201|Verrucomicrobia,2IVF7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_3529137_6	945713.IALB_3013	2.538e-09	72.0	COG1413@1|root,COG3266@1|root,COG1413@2|Bacteria,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	3.4.11.2,3.4.21.96,3.4.24.3	ko:K01256,ko:K01361,ko:K01387,ko:K03301	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002,ko02042,ko03110	2.A.12	-	-	HEAT_2,Peptidase_M9,Peptidase_M9_N
SHD3_k127_3529137_0	349520.PPE_04361	3.944e-33	150.0	COG2730@1|root,COG4124@1|root,COG4733@1|root,COG2730@2|Bacteria,COG4124@2|Bacteria,COG4733@2|Bacteria,1V0UJ@1239|Firmicutes,4HGW4@91061|Bacilli,26T9Y@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 26 family	celA7	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	CBM_3,CBM_35,Glyco_hydro_26,Glyco_hydro_44,fn3
SHD3_k127_3529137_1	1254432.SCE1572_01805	8.115e-31	133.0	COG1266@1|root,COG1266@2|Bacteria,1MWXT@1224|Proteobacteria,42XZG@68525|delta/epsilon subdivisions,2WSV7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SHD3_k127_3529137_4	187272.Mlg_1038	5.587e-17	91.0	COG1833@1|root,COG1833@2|Bacteria,1N8Y1@1224|Proteobacteria,1SDIB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function DUF123	-	-	-	-	-	-	-	-	-	-	-	-	DUF123
SHD3_k127_3529137_7	215803.DB30_6554	2.923e-06	61.0	COG1572@1|root,COG1572@2|Bacteria	2|Bacteria	NU	bacterial-type flagellum-dependent cell motility	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5011
SHD3_k127_3529137_5	1283283.ATXA01000055_gene2408	6.317e-11	70.0	28YH6@1|root,2ZKBC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3529137_3	1380387.JADM01000016_gene3800	1.847e-20	100.0	COG0515@1|root,COG0515@2|Bacteria,1QZ10@1224|Proteobacteria,1S5Y1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	KLT	Domain of unknown function (DUF4328)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4328
SHD3_k127_353063_1	448385.sce6388	2.064e-55	199.0	COG0622@1|root,COG0622@2|Bacteria,1P6AE@1224|Proteobacteria,432S1@68525|delta/epsilon subdivisions,2WXPU@28221|Deltaproteobacteria,2Z3CY@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
SHD3_k127_353063_4	67356.KL575592_gene2667	3.712e-07	57.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria	201174|Actinobacteria	T	Transcriptional regulator, TraR DksA family	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
SHD3_k127_353063_3	1190606.AJYG01000007_gene2442	2.25e-10	73.0	COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria,1XVIP@135623|Vibrionales	135623|Vibrionales	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SHD3_k127_353063_2	506534.Rhein_3236	2.185e-13	76.0	COG3385@1|root,COG3385@2|Bacteria,1R55Y@1224|Proteobacteria,1RRSD@1236|Gammaproteobacteria,1X0M5@135613|Chromatiales	135613|Chromatiales	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
SHD3_k127_3535392_2	1254432.SCE1572_35395	1.726e-74	260.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WPZ9@28221|Deltaproteobacteria,2YV95@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3535392_1	1254432.SCE1572_35390	4.236e-82	282.0	29RMJ@1|root,30CQT@2|Bacteria,1QTPA@1224|Proteobacteria,4380Z@68525|delta/epsilon subdivisions,2X3B0@28221|Deltaproteobacteria,2YV6U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3535392_0	448385.sce5945	6.923e-207	674.0	COG0457@1|root,COG0457@2|Bacteria,1Q2EC@1224|Proteobacteria,43804@68525|delta/epsilon subdivisions,2X3A2@28221|Deltaproteobacteria,2YV2B@29|Myxococcales	28221|Deltaproteobacteria	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SHD3_k127_3539768_4	1254432.SCE1572_45570	5.24e-62	219.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1R91W@1224|Proteobacteria,42PXP@68525|delta/epsilon subdivisions,2WJJX@28221|Deltaproteobacteria,2YX85@29|Myxococcales	28221|Deltaproteobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_9
SHD3_k127_3539768_1	1254432.SCE1572_45560	7.148e-137	455.0	COG4191@1|root,COG4191@2|Bacteria,1MY5P@1224|Proteobacteria,42MTA@68525|delta/epsilon subdivisions,2WJ9Q@28221|Deltaproteobacteria,2YUZA@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	4HB_MCP_1,CHASE3,HAMP,HATPase_c,HisKA
SHD3_k127_3539768_7	448385.sce7977	3.279e-12	70.0	2AJ7Q@1|root,319SI@2|Bacteria,1Q3U9@1224|Proteobacteria,435C3@68525|delta/epsilon subdivisions,2WZPM@28221|Deltaproteobacteria,2Z2H7@29|Myxococcales	28221|Deltaproteobacteria	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
SHD3_k127_3539768_3	1254432.SCE1572_45805	2.03e-90	304.0	COG0356@1|root,COG0356@2|Bacteria,1MV87@1224|Proteobacteria,42NR9@68525|delta/epsilon subdivisions,2WKX1@28221|Deltaproteobacteria,2YVR0@29|Myxococcales	28221|Deltaproteobacteria	C	it plays a direct role in the translocation of protons across the membrane	atpB	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
SHD3_k127_3539768_6	448385.sce7980	9.949e-26	110.0	COG0636@1|root,COG0636@2|Bacteria,1QAIF@1224|Proteobacteria,43A8Y@68525|delta/epsilon subdivisions,2X9Z1@28221|Deltaproteobacteria,2YW38@29|Myxococcales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
SHD3_k127_3539768_0	1192034.CAP_1789	9.81e-192	614.0	COG0661@1|root,COG0661@2|Bacteria,1MU1Z@1224|Proteobacteria,42N87@68525|delta/epsilon subdivisions,2WK1B@28221|Deltaproteobacteria,2YYJM@29|Myxococcales	28221|Deltaproteobacteria	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1,APH,WaaY
SHD3_k127_3539768_2	448385.sce7981	1.554e-130	432.0	COG1376@1|root,COG1376@2|Bacteria,1NKBB@1224|Proteobacteria,432T9@68525|delta/epsilon subdivisions,2WYN9@28221|Deltaproteobacteria,2YWNH@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SHD3_k127_3539768_5	1254432.SCE1572_45820	1.38e-45	169.0	COG1716@1|root,COG1716@2|Bacteria,1QJBG@1224|Proteobacteria,433TM@68525|delta/epsilon subdivisions,2X3EM@28221|Deltaproteobacteria,2YVQN@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_3553273_11	1192034.CAP_2081	1.401e-16	91.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
SHD3_k127_3553273_1	448385.sce7788	2.635e-94	319.0	COG4974@1|root,COG4974@2|Bacteria,1QU6A@1224|Proteobacteria,42Q4U@68525|delta/epsilon subdivisions,2WJ08@28221|Deltaproteobacteria,2YV00@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the 'phage' integrase family. XerC subfamily	xerC	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
SHD3_k127_3553273_9	1254432.SCE1572_46135	5.282e-22	108.0	2CI35@1|root,32SUG@2|Bacteria,1PZ8E@1224|Proteobacteria,43E6E@68525|delta/epsilon subdivisions,2WZV6@28221|Deltaproteobacteria,2Z2TN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3553273_2	1254432.SCE1572_46140	2.116e-88	301.0	COG1277@1|root,COG1277@2|Bacteria,1RM0H@1224|Proteobacteria,42T8A@68525|delta/epsilon subdivisions,2WPQJ@28221|Deltaproteobacteria,2YVVY@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	pilI	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_4
SHD3_k127_3553273_7	1192034.CAP_7867	6.835e-40	153.0	COG0745@1|root,COG0745@2|Bacteria	1192034.CAP_7867|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3553273_8	448385.sce5888	2.005e-31	128.0	COG2979@1|root,COG2979@2|Bacteria	2|Bacteria	T	Protein of unknown function (DUF533)	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	LETM1,TerB
SHD3_k127_3553273_6	1192034.CAP_4789	1.415e-43	177.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	FG-GAP_2,PQQ_2,PQQ_3
SHD3_k127_3553273_5	1254432.SCE1572_34935	1.999e-44	165.0	COG0316@1|root,COG0316@2|Bacteria,1RHCW@1224|Proteobacteria,431E6@68525|delta/epsilon subdivisions,2WWGA@28221|Deltaproteobacteria,2YVXB@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the HesB IscA family	-	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
SHD3_k127_3553273_0	1192034.CAP_2500	6.12e-98	330.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2Z07Q@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r4
SHD3_k127_3553273_12	759362.KVU_1965	2.053e-15	80.0	2ENFV@1|root,33G39@2|Bacteria,1NP5K@1224|Proteobacteria,2UJUH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3560538_3	452637.Oter_0060	6.884e-63	233.0	2DKW5@1|root,30J7Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3560538_0	1123508.JH636446_gene6369	1.108e-136	476.0	COG3852@1|root,COG4191@1|root,COG3852@2|Bacteria,COG4191@2|Bacteria,2IWUM@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_3560538_1	649831.L083_5542	8.213e-90	305.0	COG2755@1|root,COG2755@2|Bacteria,2GN76@201174|Actinobacteria,4D9AP@85008|Micromonosporales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_3560538_5	713586.KB900536_gene2502	2.898e-29	129.0	COG1216@1|root,COG1216@2|Bacteria,1NM61@1224|Proteobacteria,1RRUD@1236|Gammaproteobacteria,1WX3T@135613|Chromatiales	135613|Chromatiales	M	PFAM Glycosyl transferase family 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SHD3_k127_3560538_2	592015.HMPREF1705_00543	2.303e-83	292.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_3560538_4	525898.Sdel_1813	3.269e-31	129.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2YMZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SHD3_k127_3582813_6	1254432.SCE1572_21550	4.635e-11	69.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3582813_1	1192034.CAP_0509	6.127e-55	209.0	COG2755@1|root,COG2755@2|Bacteria,1R7BU@1224|Proteobacteria,43428@68525|delta/epsilon subdivisions,2X4SY@28221|Deltaproteobacteria,2YZIV@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_3582813_4	316067.Geob_3314	6.681e-29	118.0	2E7BZ@1|root,331V9@2|Bacteria,1N8MZ@1224|Proteobacteria	1224|Proteobacteria	S	Domain of Unknown Function (DUF1540)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
SHD3_k127_3582813_3	1499967.BAYZ01000148_gene1727	3.299e-34	136.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
SHD3_k127_3582813_0	404589.Anae109_0566	1.678e-171	547.0	COG2211@1|root,COG2211@2|Bacteria,1QVH9@1224|Proteobacteria,43BQR@68525|delta/epsilon subdivisions,2X71T@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SHD3_k127_3582813_2	1121405.dsmv_0268	1.352e-42	158.0	COG1695@1|root,COG1695@2|Bacteria,1RHG3@1224|Proteobacteria,42UV3@68525|delta/epsilon subdivisions,2WR1W@28221|Deltaproteobacteria,2MNUT@213118|Desulfobacterales	28221|Deltaproteobacteria	K	PFAM transcriptional regulator PadR family protein	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SHD3_k127_3583614_1	1303518.CCALI_00619	6.4e-84	298.0	COG3693@1|root,COG3693@2|Bacteria	2|Bacteria	G	endo-1,4-beta-xylanase activity	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,Glyco_hydro_10
SHD3_k127_3583614_2	1192034.CAP_0182	3.393e-10	66.0	COG0515@1|root,COG0515@2|Bacteria,1Q38C@1224|Proteobacteria,433YY@68525|delta/epsilon subdivisions,2X44H@28221|Deltaproteobacteria,2YY8C@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PEGA,Pkinase
SHD3_k127_3583614_0	448385.sce0353	1.03e-89	308.0	COG0515@1|root,COG0515@2|Bacteria,1Q38J@1224|Proteobacteria,438ZJ@68525|delta/epsilon subdivisions,2X44T@28221|Deltaproteobacteria,2YY98@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	masK	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3587849_7	243231.GSU2418	0.0002187	46.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,42PVF@68525|delta/epsilon subdivisions,2WK6U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	mvhS	-	1.8.98.5	ko:K14128	ko00680,map00680	-	R00019,R11943	RC00011	ko00000,ko00001,ko01000	-	-	-	Oxidored_q6
SHD3_k127_3587849_4	443144.GM21_3974	8.52e-30	124.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	ko:K07013,ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	V4R
SHD3_k127_3587849_2	880073.Calab_3013	7.56e-37	155.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,GGDEF,Response_reg
SHD3_k127_3587849_0	1254432.SCE1572_33925	2.5e-235	735.0	COG3104@1|root,COG3104@2|Bacteria,1MW6W@1224|Proteobacteria,42NNY@68525|delta/epsilon subdivisions,2WKK6@28221|Deltaproteobacteria,2YTWP@29|Myxococcales	28221|Deltaproteobacteria	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
SHD3_k127_3587849_1	1125863.JAFN01000001_gene2927	6.659e-165	531.0	COG0436@1|root,COG0436@2|Bacteria,1MW0Z@1224|Proteobacteria,42MQI@68525|delta/epsilon subdivisions,2WN1S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.2	ko:K00814	ko00220,ko00250,ko00710,ko01100,ko01120,ko01200,ko01210,ko01230,map00220,map00250,map00710,map01100,map01120,map01200,map01210,map01230	M00171	R00258	RC00006,RC00008	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SHD3_k127_3587849_3	713587.THITH_12510	4.811e-33	148.0	COG0421@1|root,COG0421@2|Bacteria,1MVV5@1224|Proteobacteria	1224|Proteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_3587849_5	861299.J421_0439	3.992e-05	56.0	COG1470@1|root,COG1572@1|root,COG3227@1|root,COG4447@1|root,COG1470@2|Bacteria,COG1572@2|Bacteria,COG3227@2|Bacteria,COG4447@2|Bacteria,1ZT2Y@142182|Gemmatimonadetes	142182|Gemmatimonadetes	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3589084_2	345341.KUTG_00701	1.966e-71	260.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria,4E1D9@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	AbfB,ArabFuran-catal,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_3589084_6	68223.JNZY01000011_gene1315	0.0001174	55.0	COG1501@1|root,COG3511@1|root,COG3693@1|root,COG1501@2|Bacteria,COG3511@2|Bacteria,COG3693@2|Bacteria,2GP4V@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,F5_F8_type_C,FIVAR,Glyco_hydro_31,Ricin_B_lectin
SHD3_k127_3589084_5	909613.UO65_4914	1.58e-09	71.0	COG1361@1|root,COG5520@1|root,COG1361@2|Bacteria,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF5011,Peptidase_M11,Ricin_B_lectin
SHD3_k127_3589084_3	448385.sce0469	2.686e-52	203.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce0469|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3589084_1	1192034.CAP_5604	1.506e-112	380.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
SHD3_k127_3589084_0	1173027.Mic7113_5430	8.92e-177	570.0	COG0438@1|root,COG0438@2|Bacteria,1G2C5@1117|Cyanobacteria,1H922@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
SHD3_k127_3589084_4	1192034.CAP_4938	7.774e-16	85.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	-	-	3.4.21.19	ko:K01318	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Trypsin,Trypsin_2
SHD3_k127_3592451_8	66377.JOBH01000027_gene3983	3.606e-06	58.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
SHD3_k127_3592451_4	404380.Gbem_1332	4.854e-86	297.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria,43V13@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
SHD3_k127_3592451_0	1192034.CAP_0822	1.769e-315	1004.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1N4IM@1224|Proteobacteria,437ZC@68525|delta/epsilon subdivisions,2WZWU@28221|Deltaproteobacteria,2YUXT@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_2,VWA_3
SHD3_k127_3592451_1	1192034.CAP_0821	1.768e-170	556.0	COG2304@1|root,COG2304@2|Bacteria,1QB89@1224|Proteobacteria,435EV@68525|delta/epsilon subdivisions,2WZSF@28221|Deltaproteobacteria,2Z2NJ@29|Myxococcales	28221|Deltaproteobacteria	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA,VWA_2
SHD3_k127_3592451_5	1414720.CBYM010000001_gene782	4.669e-32	138.0	COG1721@1|root,COG1721@2|Bacteria,1V2UW@1239|Firmicutes,24AGA@186801|Clostridia,36HER@31979|Clostridiaceae	186801|Clostridia	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SHD3_k127_3592451_2	1192034.CAP_7424	1.278e-133	446.0	COG1277@1|root,COG1277@2|Bacteria,1Q3SM@1224|Proteobacteria,4342Q@68525|delta/epsilon subdivisions,2X4XP@28221|Deltaproteobacteria,2YZT2@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
SHD3_k127_3592451_3	1254432.SCE1572_42855	1.451e-132	432.0	COG1131@1|root,COG1131@2|Bacteria,1MY19@1224|Proteobacteria,43479@68525|delta/epsilon subdivisions,2X1TN@28221|Deltaproteobacteria,2YUXA@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_3595261_11	398767.Glov_2304	6.855e-82	279.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,43TBH@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SHD3_k127_3595261_22	1254432.SCE1572_42280	2.397e-29	128.0	2BFUE@1|root,329PK@2|Bacteria,1QAVH@1224|Proteobacteria,435BN@68525|delta/epsilon subdivisions,2WZP4@28221|Deltaproteobacteria,2Z2G3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3595261_5	1192034.CAP_8508	1.523e-133	430.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,42RNB@68525|delta/epsilon subdivisions,2WQ81@28221|Deltaproteobacteria,2YTTJ@29|Myxococcales	28221|Deltaproteobacteria	T	Diadenosine tetraphosphatase and related serine threonine protein phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SHD3_k127_3595261_14	1192034.CAP_5019	8.325e-68	239.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	ko:K07059	-	-	-	-	ko00000	-	-	-	DnaJ_C,Rhomboid
SHD3_k127_3595261_18	1254432.SCE1572_04210	4.237e-39	154.0	2ENGZ@1|root,33G4G@2|Bacteria,1P6A6@1224|Proteobacteria,43288@68525|delta/epsilon subdivisions,2WXAP@28221|Deltaproteobacteria,2YVQY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3595261_8	1254432.SCE1572_04205	4.67e-98	334.0	COG0767@1|root,COG0767@2|Bacteria,1RHNJ@1224|Proteobacteria,42SNW@68525|delta/epsilon subdivisions,2WPKT@28221|Deltaproteobacteria,2YV5J@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter permease	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SHD3_k127_3595261_26	290397.Adeh_1662	7.295e-17	87.0	COG0789@1|root,COG0789@2|Bacteria,1MZ3P@1224|Proteobacteria,42VYV@68525|delta/epsilon subdivisions,2WRGQ@28221|Deltaproteobacteria,2Z0X7@29|Myxococcales	28221|Deltaproteobacteria	K	MerR, DNA binding	-	-	-	ko:K19591	-	M00769	-	-	ko00000,ko00002,ko01504,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
SHD3_k127_3595261_23	1151122.AQYD01000004_gene2763	7.185e-28	120.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,4FNCY@85023|Microbacteriaceae	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
SHD3_k127_3595261_16	497965.Cyan7822_0442	1.003e-53	201.0	COG2199@1|root,COG3706@2|Bacteria,1G5BB@1117|Cyanobacteria,3KGBC@43988|Cyanothece	1117|Cyanobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SHD3_k127_3595261_19	1254432.SCE1572_35210	1.28e-35	144.0	2E05E@1|root,32VTR@2|Bacteria,1N5CW@1224|Proteobacteria,431HU@68525|delta/epsilon subdivisions,2WWRZ@28221|Deltaproteobacteria,2YVXX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3595261_20	448385.sce1486	5.551e-32	134.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_3595261_30	448385.sce1487	2.104e-10	71.0	COG0457@1|root,COG0457@2|Bacteria,1QB30@1224|Proteobacteria,43E53@68525|delta/epsilon subdivisions,2WZRF@28221|Deltaproteobacteria,2Z2KD@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3595261_28	1173028.ANKO01000127_gene4174	1.242e-14	79.0	COG3577@1|root,COG3577@2|Bacteria,1G657@1117|Cyanobacteria,1HIAT@1150|Oscillatoriales	1117|Cyanobacteria	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	gag-asp_proteas
SHD3_k127_3595261_21	477974.Daud_0415	1.001e-31	133.0	COG2402@1|root,COG2402@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07065	-	-	-	-	ko00000	-	-	-	PIN
SHD3_k127_3595261_29	1449357.JQLK01000001_gene1693	4.018e-13	73.0	2DSVR@1|root,33HKS@2|Bacteria,1WKIU@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1,RHH_3,RHH_4
SHD3_k127_3595261_4	1254432.SCE1572_42310	1.086e-144	469.0	COG1509@1|root,COG1509@2|Bacteria,1MUPJ@1224|Proteobacteria,42MNR@68525|delta/epsilon subdivisions,2WJ70@28221|Deltaproteobacteria,2YU37@29|Myxococcales	28221|Deltaproteobacteria	C	lysine 2,3-aminomutase	kamA	-	5.4.3.2	ko:K01843	ko00310,map00310	-	R00461	RC00303	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,LAM_C,Radical_SAM
SHD3_k127_3595261_12	448385.sce7260	6.629e-80	280.0	COG0760@1|root,COG0760@2|Bacteria,1MZDK@1224|Proteobacteria,42RP3@68525|delta/epsilon subdivisions,2WNPA@28221|Deltaproteobacteria,2YVS3@29|Myxococcales	28221|Deltaproteobacteria	O	PFAM PpiC-type peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K03769,ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SHD3_k127_3595261_7	1192034.CAP_8511	6.297e-102	343.0	COG0528@1|root,COG0528@2|Bacteria,1MV3N@1224|Proteobacteria,42M3X@68525|delta/epsilon subdivisions,2WJDF@28221|Deltaproteobacteria,2YU4R@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
SHD3_k127_3595261_2	1192034.CAP_5367	1.404e-245	777.0	COG1138@1|root,COG1138@2|Bacteria,1MUQS@1224|Proteobacteria,42P4Q@68525|delta/epsilon subdivisions,2WK5G@28221|Deltaproteobacteria,2YU4N@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome c-type biogenesis protein	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
SHD3_k127_3595261_25	448385.sce8171	8.906e-22	100.0	2ANI1@1|root,31DGW@2|Bacteria,1QARK@1224|Proteobacteria,43E3E@68525|delta/epsilon subdivisions,2WZKG@28221|Deltaproteobacteria,2Z2BA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3595261_3	1192034.CAP_5377	1.145e-150	485.0	COG0592@1|root,COG0592@2|Bacteria,1MVD9@1224|Proteobacteria,42NQW@68525|delta/epsilon subdivisions,2WJZM@28221|Deltaproteobacteria,2YUS5@29|Myxococcales	28221|Deltaproteobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
SHD3_k127_3595261_9	1192034.CAP_5376	1.138e-83	291.0	COG1195@1|root,COG1195@2|Bacteria,1MX8N@1224|Proteobacteria,42SYJ@68525|delta/epsilon subdivisions,2WP80@28221|Deltaproteobacteria,2YV1Z@29|Myxococcales	28221|Deltaproteobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
SHD3_k127_3595261_1	1192034.CAP_5375	0.0	1069.0	COG0187@1|root,COG0187@2|Bacteria,1MVKT@1224|Proteobacteria,42M7M@68525|delta/epsilon subdivisions,2WJ9X@28221|Deltaproteobacteria,2YU54@29|Myxococcales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
SHD3_k127_3595261_0	1192034.CAP_5374	0.0	1205.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2YUBF@29|Myxococcales	28221|Deltaproteobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SHD3_k127_3595261_24	335543.Sfum_3424	6.577e-23	105.0	2CFD1@1|root,2ZMI9@2|Bacteria,1P8BR@1224|Proteobacteria,4324N@68525|delta/epsilon subdivisions,2WYA2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4405)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4405
SHD3_k127_3595261_6	448385.sce1586	2.625e-130	422.0	2BRF1@1|root,32KDW@2|Bacteria,1Q2SY@1224|Proteobacteria,438ER@68525|delta/epsilon subdivisions,2X3PP@28221|Deltaproteobacteria,2YWSS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3595261_10	251221.35214018	1.963e-83	291.0	COG1162@1|root,COG1162@2|Bacteria,1G18W@1117|Cyanobacteria	1117|Cyanobacteria	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	-	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
SHD3_k127_3595261_15	1121935.AQXX01000048_gene5279	8.182e-67	241.0	COG3291@1|root,COG3866@1|root,COG3291@2|Bacteria,COG3866@2|Bacteria,1R9Q3@1224|Proteobacteria,1S3TY@1236|Gammaproteobacteria,1XQ8E@135619|Oceanospirillales	135619|Oceanospirillales	G	Amb_all	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	Pec_lyase_C
SHD3_k127_3595261_31	1192034.CAP_9030	3.709e-06	58.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
SHD3_k127_3595261_27	1192034.CAP_6604	2.342e-15	79.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_3597395_11	1123504.JQKD01000012_gene1238	3.035e-42	163.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria	1224|Proteobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SHD3_k127_3597395_15	298654.FraEuI1c_3899	1.514e-10	64.0	2DSDZ@1|root,33FQR@2|Bacteria	2|Bacteria	S	Bacterial antitoxin of type II TA system, VapB	-	-	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
SHD3_k127_3597395_16	866536.Belba_2375	9.988e-09	59.0	COG2337@1|root,COG2337@2|Bacteria,4NRIX@976|Bacteroidetes	976|Bacteroidetes	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SHD3_k127_3597395_14	429009.Adeg_2177	3.531e-11	73.0	COG2253@1|root,COG2253@2|Bacteria,1UYJB@1239|Firmicutes,24G9I@186801|Clostridia	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SHD3_k127_3597395_3	448385.sce8524	1.832e-135	439.0	COG0150@1|root,COG0150@2|Bacteria,1MURG@1224|Proteobacteria,42KZT@68525|delta/epsilon subdivisions,2WIXY@28221|Deltaproteobacteria,2YTTG@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphoribosylformylglycinamidine cyclo-ligase	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1844	AIRS,AIRS_C
SHD3_k127_3597395_6	1254432.SCE1572_49405	3.629e-78	266.0	COG0299@1|root,COG0299@2|Bacteria,1MWN1@1224|Proteobacteria,42R30@68525|delta/epsilon subdivisions,2WJT0@28221|Deltaproteobacteria,2YVC1@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
SHD3_k127_3597395_1	1254432.SCE1572_49400	9.376e-177	571.0	COG1233@1|root,COG1233@2|Bacteria,1Q2HN@1224|Proteobacteria,4384H@68525|delta/epsilon subdivisions,2X3EF@28221|Deltaproteobacteria,2YVQ0@29|Myxococcales	28221|Deltaproteobacteria	Q	COG1233 Phytoene dehydrogenase and related	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_8
SHD3_k127_3597395_12	1254432.SCE1572_46755	6.969e-41	170.0	29RQC@1|root,30CTT@2|Bacteria,1QTPW@1224|Proteobacteria,435D4@68525|delta/epsilon subdivisions,2WZQP@28221|Deltaproteobacteria,2Z2IY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SHD3_k127_3597395_10	1192034.CAP_1417	5.879e-43	164.0	COG0742@1|root,COG0742@2|Bacteria,1MXKW@1224|Proteobacteria,42U1F@68525|delta/epsilon subdivisions,2WQQM@28221|Deltaproteobacteria,2YVK3@29|Myxococcales	28221|Deltaproteobacteria	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
SHD3_k127_3597395_17	448385.sce5360	8.51e-08	61.0	COG1716@1|root,COG2304@1|root,COG4676@1|root,COG4783@1|root,COG1716@2|Bacteria,COG2304@2|Bacteria,COG4676@2|Bacteria,COG4783@2|Bacteria,1PCRX@1224|Proteobacteria,433WB@68525|delta/epsilon subdivisions,2X9AU@28221|Deltaproteobacteria,2YX4K@29|Myxococcales	28221|Deltaproteobacteria	E	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	VIT
SHD3_k127_3597395_7	1254432.SCE1572_46765	2.694e-77	269.0	COG0101@1|root,COG0101@2|Bacteria,1MUYI@1224|Proteobacteria,42RTC@68525|delta/epsilon subdivisions,2WNQ6@28221|Deltaproteobacteria,2YVHB@29|Myxococcales	28221|Deltaproteobacteria	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
SHD3_k127_3597395_0	1192034.CAP_4595	9.886e-206	653.0	COG0156@1|root,COG0156@2|Bacteria,1MVVH@1224|Proteobacteria,42MM1@68525|delta/epsilon subdivisions,2WIU7@28221|Deltaproteobacteria,2YX7Y@29|Myxococcales	28221|Deltaproteobacteria	E	Beta-eliminating lyase	bioF1	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
SHD3_k127_3597395_2	1254432.SCE1572_42005	4.672e-146	471.0	COG0454@1|root,COG0456@2|Bacteria,1PMA3@1224|Proteobacteria,42PYX@68525|delta/epsilon subdivisions,2WKSE@28221|Deltaproteobacteria,2YUVH@29|Myxococcales	28221|Deltaproteobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3597395_5	448385.sce7198	1.889e-102	344.0	COG0451@1|root,COG0451@2|Bacteria,1MX2J@1224|Proteobacteria,42TZR@68525|delta/epsilon subdivisions,2WQAW@28221|Deltaproteobacteria,2YV9A@29|Myxococcales	28221|Deltaproteobacteria	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SHD3_k127_3597395_13	1415780.JPOG01000001_gene182	1.511e-22	107.0	2E4SV@1|root,32ZM7@2|Bacteria,1N8VN@1224|Proteobacteria,1S6AW@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
SHD3_k127_3597395_4	1177181.T9A_03079	1.094e-102	352.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,1RMSE@1236|Gammaproteobacteria,1XIBT@135619|Oceanospirillales	135619|Oceanospirillales	E	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
SHD3_k127_3604561_3	1254432.SCE1572_20425	1.61e-37	160.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14,PD40,PKD
SHD3_k127_3604561_1	1254432.SCE1572_30995	1.564e-86	303.0	COG0515@1|root,COG0515@2|Bacteria	1254432.SCE1572_30995|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3604561_2	391625.PPSIR1_03008	1.053e-55	210.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SHD3_k127_3604561_0	1254432.SCE1572_31085	1.014e-311	988.0	COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,42M70@68525|delta/epsilon subdivisions,2WJA8@28221|Deltaproteobacteria,2YU3X@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
SHD3_k127_3604561_4	945712.CULC22_00302	0.0007936	44.0	COG0812@1|root,COG0812@2|Bacteria,2GIV2@201174|Actinobacteria,22JJP@1653|Corynebacteriaceae	201174|Actinobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SHD3_k127_3607368_2	1122194.AUHU01000003_gene2068	2.061e-54	198.0	COG2730@1|root,COG2730@2|Bacteria,1R9PR@1224|Proteobacteria,1S1CE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 45	-	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	-	-	-	-	-	-	-	-	-	CBM_10,CBM_2,Glyco_hydro_45
SHD3_k127_3607368_4	391625.PPSIR1_28123	9.758e-41	172.0	COG4402@1|root,COG4402@2|Bacteria,1MVMM@1224|Proteobacteria	1224|Proteobacteria	M	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
SHD3_k127_3607368_5	1192034.CAP_5282	8.08e-37	160.0	COG0494@1|root,COG0494@2|Bacteria,1QXXS@1224|Proteobacteria,43C8Y@68525|delta/epsilon subdivisions,2X7JB@28221|Deltaproteobacteria,2YVVN@29|Myxococcales	28221|Deltaproteobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
SHD3_k127_3607368_6	1254432.SCE1572_42520	1.999e-30	128.0	COG2260@1|root,COG2260@2|Bacteria	2|Bacteria	J	snoRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007
SHD3_k127_3607368_3	448385.sce2650	2.223e-53	199.0	COG0671@1|root,COG0671@2|Bacteria,1RF0K@1224|Proteobacteria,4384K@68525|delta/epsilon subdivisions,2X3EK@28221|Deltaproteobacteria,2YVQJ@29|Myxococcales	28221|Deltaproteobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
SHD3_k127_3607368_0	404589.Anae109_0667	4.771e-233	734.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIPP@28221|Deltaproteobacteria,2YTYC@29|Myxococcales	28221|Deltaproteobacteria	NU	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB	pilB	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N,cNMP_binding
SHD3_k127_3607368_1	404589.Anae109_0668	3.493e-178	564.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WIMF@28221|Deltaproteobacteria,2YWXD@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT-4	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SHD3_k127_3607368_7	204669.Acid345_4447	3.491e-26	120.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria,2JJB9@204432|Acidobacteriia	204432|Acidobacteriia	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SHD3_k127_3614919_5	631362.Thi970DRAFT_04048	9.598e-25	109.0	COG0647@1|root,COG0647@2|Bacteria,1QHTN@1224|Proteobacteria,1S8KM@1236|Gammaproteobacteria,1WZUP@135613|Chromatiales	135613|Chromatiales	G	PFAM Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
SHD3_k127_3614919_2	3075.A0A087SKI8	2.831e-65	227.0	COG0221@1|root,KOG1626@2759|Eukaryota,37R74@33090|Viridiplantae	33090|Viridiplantae	C	soluble inorganic	-	GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0008150,GO:0010035,GO:0010038,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyrophosphatase
SHD3_k127_3614919_0	1254432.SCE1572_01775	4.619e-144	486.0	COG1719@1|root,COG3829@1|root,COG1719@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42M2E@68525|delta/epsilon subdivisions,2WKAB@28221|Deltaproteobacteria,2YWDZ@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,V4R,XylR_N
SHD3_k127_3614919_3	869210.Marky_1794	4.449e-37	156.0	COG0624@1|root,COG0624@2|Bacteria,1WJ84@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	PFAM Peptidase family M20 M25 M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
SHD3_k127_3614919_1	515635.Dtur_0938	2.313e-85	296.0	COG0282@1|root,COG0282@2|Bacteria	2|Bacteria	F	acetate kinase activity	ackA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv0409	Acetate_kinase
SHD3_k127_3620586_3	237368.SCABRO_00535	5.524e-20	104.0	COG3637@1|root,COG3637@2|Bacteria,2J46X@203682|Planctomycetes	203682|Planctomycetes	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3620586_1	331678.Cphamn1_0650	7.201e-42	162.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SHD3_k127_3620586_2	1232410.KI421425_gene1566	1.936e-41	158.0	COG3474@1|root,COG3474@2|Bacteria,1QUNA@1224|Proteobacteria,42PVG@68525|delta/epsilon subdivisions,2X7M4@28221|Deltaproteobacteria,43VY9@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3620586_0	861299.J421_3630	3.045e-173	577.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,1ZSRY@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,TAT_signal
SHD3_k127_3622939_11	7719.XP_002122504.2	2.948e-05	57.0	COG5640@1|root,KOG4475@1|root,KOG3627@2759|Eukaryota,KOG4475@2759|Eukaryota,39S5Z@33154|Opisthokonta,3BKRV@33208|Metazoa,3D24J@33213|Bilateria,48JTN@7711|Chordata	33208|Metazoa	O	Trypsin-like serine protease	-	-	-	ko:K09640	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	TSP_1,Trypsin
SHD3_k127_3622939_2	483219.LILAB_11200	4.059e-42	165.0	COG1360@1|root,COG1360@2|Bacteria,1MU4S@1224|Proteobacteria,42RH7@68525|delta/epsilon subdivisions,2WP03@28221|Deltaproteobacteria,2YV7N@29|Myxococcales	28221|Deltaproteobacteria	N	OmpA family	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SHD3_k127_3622939_1	1041930.Mtc_0454	1.922e-53	207.0	COG0540@1|root,arCOG00911@2157|Archaea,2XSZ7@28890|Euryarchaeota,2N99Z@224756|Methanomicrobia	224756|Methanomicrobia	F	aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	iAF692.Mbar_A1168	OTCace,OTCace_N
SHD3_k127_3622939_4	593750.Metfor_0412	1.607e-33	140.0	COG1670@1|root,arCOG00842@2157|Archaea	2157|Archaea	J	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SHD3_k127_3622939_9	448385.sce4715	1.414e-06	60.0	2AGKM@1|root,316TT@2|Bacteria,1PY02@1224|Proteobacteria,43DZS@68525|delta/epsilon subdivisions,2WZAI@28221|Deltaproteobacteria,2Z1Q4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3622939_5	1254432.SCE1572_15940	2.961e-15	89.0	2DSXQ@1|root,33HVC@2|Bacteria,1N9KU@1224|Proteobacteria	1224|Proteobacteria	S	Kazal type serine protease inhibitors	-	-	-	-	-	-	-	-	-	-	-	-	Kazal_1,Kazal_2
SHD3_k127_3622939_6	1192034.CAP_9030	3.936e-15	86.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
SHD3_k127_3622939_3	1192034.CAP_9029	1.928e-41	160.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3622939_0	397945.Aave_2156	4.908e-125	418.0	COG2931@1|root,COG2931@2|Bacteria,1R4CQ@1224|Proteobacteria	1224|Proteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_362390_2	1460634.JCM19037_2836	0.0009594	44.0	COG4221@1|root,COG4221@2|Bacteria,1TRHF@1239|Firmicutes,4HBXH@91061|Bacilli	91061|Bacilli	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_362390_0	29875.EHK20789	1.238e-144	477.0	2D0SS@1|root,2SFAG@2759|Eukaryota,3AE77@33154|Opisthokonta,3P9GB@4751|Fungi,3R0TS@4890|Ascomycota,21NKN@147550|Sordariomycetes,3TWBD@5125|Hypocreales,3TYPI@5129|Hypocreaceae	4751|Fungi	S	Pollen allergen	-	GO:0005575,GO:0005623,GO:0009986,GO:0044464	-	-	-	-	-	-	-	-	-	-	CBM_1,Pollen_allerg_1
SHD3_k127_362390_1	906968.Trebr_2556	7.795e-74	280.0	COG4677@1|root,COG4677@2|Bacteria,2J9H3@203691|Spirochaetes	203691|Spirochaetes	G	pectinesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Pectinesterase
SHD3_k127_3634687_0	880072.Desac_2378	1.785e-31	125.0	COG0366@1|root,COG0754@1|root,COG0366@2|Bacteria,COG0754@2|Bacteria,1PDXT@1224|Proteobacteria,43789@68525|delta/epsilon subdivisions,2X2AW@28221|Deltaproteobacteria,2MS3Q@213462|Syntrophobacterales	28221|Deltaproteobacteria	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
SHD3_k127_3634687_2	1396141.BATP01000059_gene2438	3.059e-08	62.0	COG0469@1|root,COG0469@2|Bacteria,46SBJ@74201|Verrucomicrobia,2ITNV@203494|Verrucomicrobiae	2|Bacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SHD3_k127_3634687_4	1267533.KB906737_gene1714	1.996e-05	58.0	COG3292@1|root,COG4585@1|root,COG3292@2|Bacteria,COG4585@2|Bacteria,3Y2ZI@57723|Acidobacteria,2JIKK@204432|Acidobacteriia	204432|Acidobacteriia	T	Two component regulator propeller	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3,Reg_prop,Y_Y_Y
SHD3_k127_3634687_3	1144275.COCOR_05928	1.278e-05	57.0	COG4447@1|root,COG4447@2|Bacteria,1PK4F@1224|Proteobacteria,437G7@68525|delta/epsilon subdivisions,2XA3A@28221|Deltaproteobacteria,2YVKV@29|Myxococcales	28221|Deltaproteobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3638331_8	1254432.SCE1572_26350	1.397e-29	133.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_26350|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3638331_5	1192034.CAP_2370	1.579e-43	178.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_2370|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3638331_12	861299.J421_5728	8.388e-08	60.0	COG4191@1|root,COG4936@1|root,COG4191@2|Bacteria,COG4936@2|Bacteria,1ZUC5@142182|Gemmatimonadetes	142182|Gemmatimonadetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SHD3_k127_3638331_11	693979.Bache_1381	8.82e-12	72.0	COG0642@1|root,COG0745@1|root,COG3292@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,COG3292@2|Bacteria,4NITX@976|Bacteroidetes,2FM2F@200643|Bacteroidia,4ANIP@815|Bacteroidaceae	976|Bacteroidetes	T	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg
SHD3_k127_3638331_2	448385.sce9360	3.891e-102	340.0	COG0224@1|root,COG0224@2|Bacteria,1MU28@1224|Proteobacteria,42N8B@68525|delta/epsilon subdivisions,2WJ6I@28221|Deltaproteobacteria,2YUV1@29|Myxococcales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
SHD3_k127_3638331_0	448385.sce9361	8.469e-247	776.0	COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,42MVX@68525|delta/epsilon subdivisions,2WIK7@28221|Deltaproteobacteria,2YUF7@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
SHD3_k127_3638331_6	1192034.CAP_3137	1.517e-40	159.0	COG0712@1|root,COG0712@2|Bacteria,1MVRH@1224|Proteobacteria,42U68@68525|delta/epsilon subdivisions,2WQJS@28221|Deltaproteobacteria,2Z301@29|Myxococcales	28221|Deltaproteobacteria	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
SHD3_k127_3638331_9	1192034.CAP_3136	4.862e-26	117.0	COG0711@1|root,COG0711@2|Bacteria,1N97K@1224|Proteobacteria,42VYP@68525|delta/epsilon subdivisions,2WZJJ@28221|Deltaproteobacteria,2Z29S@29|Myxococcales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SHD3_k127_3638331_7	1254432.SCE1572_52700	6.443e-33	134.0	COG0711@1|root,COG0711@2|Bacteria,1Q25M@1224|Proteobacteria,437SR@68525|delta/epsilon subdivisions,2X31U@28221|Deltaproteobacteria,2Z2TD@29|Myxococcales	28221|Deltaproteobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
SHD3_k127_3638331_4	926554.KI912669_gene4989	1.279e-43	164.0	COG0801@1|root,COG0801@2|Bacteria,1WJU9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	folK	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
SHD3_k127_3638331_1	448385.sce8438	2.345e-116	403.0	COG0484@1|root,COG0484@2|Bacteria	2|Bacteria	O	heat shock protein binding	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SHD3_k127_3638331_3	318996.AXAZ01000113_gene348	2.771e-78	281.0	COG0451@1|root,COG0451@2|Bacteria,1PB4Y@1224|Proteobacteria,2TTV7@28211|Alphaproteobacteria,3JWIV@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SHD3_k127_3638331_13	1254432.SCE1572_03140	2.74e-07	55.0	2EGZK@1|root,33ARQ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3653874_9	1192034.CAP_0886	5.266e-67	233.0	COG0293@1|root,COG0293@2|Bacteria,1MW1C@1224|Proteobacteria,42T4F@68525|delta/epsilon subdivisions,2WP6B@28221|Deltaproteobacteria,2YVEY@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit	ftsJ	-	2.1.1.166	ko:K02427	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ
SHD3_k127_3653874_4	1254432.SCE1572_38850	9.819e-122	411.0	COG0564@1|root,COG1092@1|root,COG0564@2|Bacteria,COG1092@2|Bacteria,1PUHQ@1224|Proteobacteria,42Q87@68525|delta/epsilon subdivisions,2WPIN@28221|Deltaproteobacteria,2Z02J@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the methyltransferase superfamily	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PseudoU_synth_2
SHD3_k127_3653874_7	1254432.SCE1572_12105	2.629e-89	301.0	COG0087@1|root,COG0087@2|Bacteria,1MUST@1224|Proteobacteria,42NV2@68525|delta/epsilon subdivisions,2WNJ1@28221|Deltaproteobacteria,2YV8C@29|Myxococcales	28221|Deltaproteobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
SHD3_k127_3653874_15	448385.sce2517	7.724e-41	156.0	COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,42TMU@68525|delta/epsilon subdivisions,2WQ67@28221|Deltaproteobacteria,2Z0HV@29|Myxococcales	28221|Deltaproteobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
SHD3_k127_3653874_18	448385.sce2516	3.375e-33	143.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA
SHD3_k127_3653874_2	1192034.CAP_4577	2.39e-211	686.0	COG1240@1|root,COG1716@1|root,COG1240@2|Bacteria,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	bchD	-	6.6.1.1	ko:K03404,ko:K07114	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3653874_8	1192034.CAP_4578	1.819e-73	262.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WP2A@28221|Deltaproteobacteria,2YV2K@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
SHD3_k127_3653874_1	448385.sce8989	1.597e-291	940.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_3653874_0	448385.sce2512	0.0	1196.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1MX27@1224|Proteobacteria	1224|Proteobacteria	TV	ABC-type multidrug transport system ATPase component	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
SHD3_k127_3653874_21	42256.RradSPS_0565	3.502e-23	111.0	COG0589@1|root,COG0589@2|Bacteria,2GSJK@201174|Actinobacteria,4CQXK@84995|Rubrobacteria	201174|Actinobacteria	T	COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms	uspA2	-	-	-	-	-	-	-	-	-	-	-	Usp
SHD3_k127_3653874_3	391625.PPSIR1_30125	3.87e-132	435.0	COG1207@1|root,COG1207@2|Bacteria,1R7DE@1224|Proteobacteria,42N1D@68525|delta/epsilon subdivisions,2WIRZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	-	-	2.7.7.23,2.7.7.83	ko:K00972	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00361,M00362	R00416	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	-
SHD3_k127_3653874_10	491205.JARQ01000001_gene936	1.643e-65	250.0	COG1807@1|root,COG1807@2|Bacteria,4PAM6@976|Bacteroidetes,1IH65@117743|Flavobacteriia,3ZT5C@59732|Chryseobacterium	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3653874_24	448385.sce8516	9.419e-09	67.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.55,3.2.1.91	ko:K19668,ko:K20844	ko00500,ko00520,ko01100,ko02020,map00500,map00520,map01100,map02020	-	R01762,R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	CBM42,GH54,GH6	-	ArabFuran-catal,CBM_2,Glyco_hydro_66,RicinB_lectin_2,Ricin_B_lectin,fn3
SHD3_k127_3653874_22	269798.CHU_0569	3.914e-21	109.0	COG0457@1|root,COG0457@2|Bacteria,4NMZG@976|Bacteroidetes,47MTB@768503|Cytophagia	976|Bacteroidetes	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1736,PMT_2,TPR_16,TPR_2,TPR_8
SHD3_k127_3653874_11	1255043.TVNIR_1877	2.672e-65	233.0	COG0842@1|root,COG0842@2|Bacteria,1N55T@1224|Proteobacteria,1S29T@1236|Gammaproteobacteria,1X0GP@135613|Chromatiales	135613|Chromatiales	V	TIGRFAM ABC-2 type transporter, NodJ	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
SHD3_k127_3653874_6	1120949.KB903305_gene7174	1.66e-99	334.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4DAC8@85008|Micromonosporales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
SHD3_k127_3653874_13	1254432.SCE1572_41655	5.243e-45	171.0	COG1611@1|root,COG1611@2|Bacteria,1RJ91@1224|Proteobacteria,42TR7@68525|delta/epsilon subdivisions,2WQUE@28221|Deltaproteobacteria,2Z1AI@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM conserved	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	DNA_processg_A,Lysine_decarbox
SHD3_k127_3653874_17	448385.sce5231	2.119e-34	148.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3653874_5	640511.BC1002_6699	1.167e-103	354.0	COG1032@1|root,COG1032@2|Bacteria,1R92G@1224|Proteobacteria,2WB71@28216|Betaproteobacteria,1K09Q@119060|Burkholderiaceae	28216|Betaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_3653874_16	1121920.AUAU01000021_gene2521	1.96e-35	145.0	COG3809@1|root,COG3809@2|Bacteria,3Y803@57723|Acidobacteria	57723|Acidobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	DZR,zf-TFIIB
SHD3_k127_3653874_14	1254432.SCE1572_23805	4.009e-44	177.0	28HBS@1|root,2Z7NR@2|Bacteria,1MVH3@1224|Proteobacteria,434WA@68525|delta/epsilon subdivisions,2WZ78@28221|Deltaproteobacteria,2Z1H7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3653874_20	555079.Toce_0227	5.832e-26	110.0	COG3829@1|root,COG3829@2|Bacteria,1VBSS@1239|Firmicutes	1239|Firmicutes	KT	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3653874_23	502025.Hoch_4695	6.033e-17	92.0	COG4932@1|root,COG4932@2|Bacteria,1QXTV@1224|Proteobacteria,43C6B@68525|delta/epsilon subdivisions,2X7GH@28221|Deltaproteobacteria,2YXCU@29|Myxococcales	28221|Deltaproteobacteria	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SHD3_k127_3653874_12	502025.Hoch_4695	4.513e-54	202.0	COG4932@1|root,COG4932@2|Bacteria,1QXTV@1224|Proteobacteria,43C6B@68525|delta/epsilon subdivisions,2X7GH@28221|Deltaproteobacteria,2YXCU@29|Myxococcales	28221|Deltaproteobacteria	M	CarboxypepD_reg-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg
SHD3_k127_3655800_8	435591.BDI_1330	4.524e-16	85.0	COG0558@1|root,COG0558@2|Bacteria,4NWDJ@976|Bacteroidetes,2FW32@200643|Bacteroidia,2316P@171551|Porphyromonadaceae	976|Bacteroidetes	I	Domain of unknown function (DUF4833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4833
SHD3_k127_3655800_5	1192034.CAP_6887	1.518e-40	174.0	COG2911@1|root,COG2911@2|Bacteria,1N4HK@1224|Proteobacteria,438QH@68525|delta/epsilon subdivisions,2X912@28221|Deltaproteobacteria,2YXIA@29|Myxococcales	28221|Deltaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3655800_0	313624.NSP_34990	0.0	1144.0	COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria,1HUA6@1161|Nostocales	1117|Cyanobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SHD3_k127_3655800_6	448385.sce5988	7.225e-29	120.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria	1224|Proteobacteria	S	PFAM RNP-1 like RNA-binding protein	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SHD3_k127_3655800_1	1122963.AUHB01000011_gene1416	3.217e-158	504.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,2TRHS@28211|Alphaproteobacteria,36Y4X@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SHD3_k127_3655800_7	357808.RoseRS_4272	1.672e-16	94.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3655800_3	589865.DaAHT2_0873	8.626e-97	330.0	COG3287@1|root,COG3287@2|Bacteria,1R474@1224|Proteobacteria,42PVH@68525|delta/epsilon subdivisions,2WMB4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SHD3_k127_3655800_4	204669.Acid345_3014	5.069e-89	322.0	COG0784@1|root,COG2202@1|root,COG2203@1|root,COG4191@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG4191@2|Bacteria,3Y64H@57723|Acidobacteria,2JM5F@204432|Acidobacteriia	204432|Acidobacteriia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_3655800_2	1121957.ATVL01000007_gene2074	2.074e-121	407.0	COG3664@1|root,COG3664@2|Bacteria,4NHQ0@976|Bacteroidetes,47N7Z@768503|Cytophagia	976|Bacteroidetes	G	PFAM glycoside hydrolase family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
SHD3_k127_3655874_0	1316936.K678_12102	9.36e-79	266.0	COG1830@1|root,COG1830@2|Bacteria,1MWJW@1224|Proteobacteria,2U27K@28211|Alphaproteobacteria,2JUUK@204441|Rhodospirillales	204441|Rhodospirillales	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SHD3_k127_3655874_2	448385.sce4032	1.49e-13	76.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_3655874_1	760192.Halhy_5381	2.829e-46	180.0	2A087@1|root,30NBF@2|Bacteria,4NMD0@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3655874_3	1463917.JODC01000005_gene6463	5.464e-12	76.0	COG4402@1|root,COG4402@2|Bacteria,2I90K@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2330
SHD3_k127_3656580_6	338966.Ppro_3522	3.676e-11	75.0	COG1143@1|root,COG1143@2|Bacteria,1RK71@1224|Proteobacteria,42Y1X@68525|delta/epsilon subdivisions,2WQB3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	ko:K14091	-	-	-	-	ko00000	-	-	-	ETF_QO,Fer4,Fer4_7
SHD3_k127_3656580_2	338966.Ppro_3523	2.543e-61	215.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SHD3_k127_3656580_3	338966.Ppro_3523	7.227e-53	190.0	COG1005@1|root,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria	68525|delta/epsilon subdivisions	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SHD3_k127_3656580_0	338966.Ppro_3524	9.097e-162	522.0	COG3261@1|root,COG3261@2|Bacteria,1QUBF@1224|Proteobacteria,43DST@68525|delta/epsilon subdivisions,2WJ4E@28221|Deltaproteobacteria,43TGG@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH-ubiquinone oxidoreductase, chain 49kDa	-	-	1.6.5.3	ko:K00333,ko:K14090	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa,NiFeSe_Hases
SHD3_k127_3656580_4	338966.Ppro_3525	1.118e-34	145.0	COG0852@1|root,COG0852@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases
SHD3_k127_3656580_1	338966.Ppro_0593	3.165e-69	238.0	COG3260@1|root,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,42NH3@68525|delta/epsilon subdivisions,2WNT3@28221|Deltaproteobacteria,43UYP@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	PFAM NADH ubiquinone oxidoreductase 20 kDa subunit	-	-	-	ko:K14088	-	-	-	-	ko00000	-	-	-	Oxidored_q6
SHD3_k127_3657200_3	118168.MC7420_323	7.403e-05	48.0	2E3CI@1|root,32YBU@2|Bacteria,1GAH6@1117|Cyanobacteria,1HDX8@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SHD3_k127_3657200_1	903818.KI912268_gene1481	5.862e-63	244.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
SHD3_k127_3657200_2	224325.AF_1461	3.651e-09	59.0	COG1146@1|root,arCOG02587@2157|Archaea	2157|Archaea	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SHD3_k127_3657200_0	391625.PPSIR1_40645	5.513e-132	433.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2YTVT@29|Myxococcales	28221|Deltaproteobacteria	C	Fe-S oxidoreductases	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_365876_10	1210884.HG799468_gene13752	1.583e-05	58.0	COG0642@1|root,COG0784@1|root,COG2197@1|root,COG0784@2|Bacteria,COG2197@2|Bacteria,COG2205@2|Bacteria,2IX8Z@203682|Planctomycetes	203682|Planctomycetes	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,PAS_4,Response_reg
SHD3_k127_365876_7	1220534.B655_1999	1.139e-24	120.0	COG0642@1|root,COG0784@1|root,arCOG02348@1|root,arCOG02352@1|root,arCOG06712@1|root,arCOG02348@2157|Archaea,arCOG02352@2157|Archaea,arCOG02358@2157|Archaea,arCOG06537@2157|Archaea,arCOG06712@2157|Archaea	2157|Archaea	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg
SHD3_k127_365876_6	215803.DB30_0979	1.897e-38	164.0	COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1Q3JJ@1224|Proteobacteria,439CF@68525|delta/epsilon subdivisions,2X4KQ@28221|Deltaproteobacteria,2YZ7Q@29|Myxococcales	28221|Deltaproteobacteria	T	RsbT co-antagonist protein rsbRD N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS_9,RsbRD_N
SHD3_k127_365876_9	391625.PPSIR1_07987	8.977e-06	56.0	2BQRM@1|root,32JN9@2|Bacteria,1PDHV@1224|Proteobacteria,435GS@68525|delta/epsilon subdivisions,2WZUA@28221|Deltaproteobacteria,2Z2RV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_365876_5	401053.AciPR4_0436	7.294e-42	156.0	2CC1B@1|root,32RUI@2|Bacteria,3Y56C@57723|Acidobacteria,2JJRT@204432|Acidobacteriia	204432|Acidobacteriia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_365876_3	1254432.SCE1572_42845	1.031e-76	273.0	COG0515@1|root,COG0515@2|Bacteria	1254432.SCE1572_42845|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SHD3_k127_365876_0	661478.OP10G_1294	3.949e-274	867.0	COG3533@1|root,COG3533@2|Bacteria	2|Bacteria	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	F5_F8_type_C,Glyco_hydro_127
SHD3_k127_365876_4	1121382.JQKG01000003_gene4306	6.321e-59	214.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	yisR	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
SHD3_k127_365876_1	641107.CDLVIII_3062	1.761e-119	406.0	COG3664@1|root,COG3664@2|Bacteria,1UHGX@1239|Firmicutes,24HX5@186801|Clostridia,36RFV@31979|Clostridiaceae	186801|Clostridia	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39
SHD3_k127_365876_2	1121373.KB903644_gene3398	5.218e-90	302.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Pec_lyase_C
SHD3_k127_3660349_14	28072.Nos7524_0074	7.893e-05	54.0	COG0457@1|root,COG0457@2|Bacteria,1G0IA@1117|Cyanobacteria,1HM3X@1161|Nostocales	1117|Cyanobacteria	S	PFAM Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6
SHD3_k127_3660349_11	1254432.SCE1572_50770	1.203e-28	126.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_50770|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3660349_3	1254432.SCE1572_50810	9.307e-172	551.0	COG0104@1|root,COG0104@2|Bacteria,1MU5B@1224|Proteobacteria,42M9E@68525|delta/epsilon subdivisions,2WJ3F@28221|Deltaproteobacteria,2YUGA@29|Myxococcales	28221|Deltaproteobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
SHD3_k127_3660349_8	1254432.SCE1572_17635	1.647e-43	168.0	COG2214@1|root,COG2214@2|Bacteria	2|Bacteria	O	Heat shock protein DnaJ domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SHD3_k127_3660349_4	1192034.CAP_3939	1.506e-145	471.0	COG1597@1|root,COG1597@2|Bacteria,1Q2E6@1224|Proteobacteria,437ZZ@68525|delta/epsilon subdivisions,2X9TP@28221|Deltaproteobacteria,2YV1J@29|Myxococcales	28221|Deltaproteobacteria	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SHD3_k127_3660349_5	1192034.CAP_3942	8.932e-125	407.0	COG0536@1|root,COG0536@2|Bacteria,1MUGZ@1224|Proteobacteria,42M40@68525|delta/epsilon subdivisions,2WIM4@28221|Deltaproteobacteria,2YUC0@29|Myxococcales	28221|Deltaproteobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
SHD3_k127_3660349_1	1121920.AUAU01000002_gene2086	4.258e-319	996.0	COG3256@1|root,COG3256@2|Bacteria,3Y2GQ@57723|Acidobacteria	2|Bacteria	P	Cytochrome C and Quinol oxidase polypeptide I	norZ	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
SHD3_k127_3660349_6	1408473.JHXO01000008_gene2655	2.785e-117	396.0	COG0330@1|root,COG0330@2|Bacteria,4NH8V@976|Bacteroidetes,2FQPC@200643|Bacteroidia	976|Bacteroidetes	O	SPFH Band 7 PHB domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
SHD3_k127_3660349_12	246197.MXAN_4815	4.052e-13	74.0	COG1544@1|root,COG1544@2|Bacteria,1N8CQ@1224|Proteobacteria,4387F@68525|delta/epsilon subdivisions,2X3HC@28221|Deltaproteobacteria,2YW3C@29|Myxococcales	28221|Deltaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
SHD3_k127_3660349_13	379066.GAU_0983	3.527e-09	61.0	COG2261@1|root,COG2261@2|Bacteria,1ZU62@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
SHD3_k127_3660349_2	452637.Oter_3558	7.288e-224	704.0	COG1032@1|root,COG1032@2|Bacteria,46V7P@74201|Verrucomicrobia,3K74V@414999|Opitutae	414999|Opitutae	C	Domain of unknown function (DUF4070)	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,DUF4070,Radical_SAM
SHD3_k127_3660349_0	304371.MCP_1979	1.635e-321	1008.0	COG0474@1|root,arCOG01578@2157|Archaea,2XW9Y@28890|Euryarchaeota,2N9BB@224756|Methanomicrobia	224756|Methanomicrobia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SHD3_k127_366109_5	1535287.JP74_11520	1.033e-28	126.0	COG0657@1|root,COG0657@2|Bacteria,1N3TH@1224|Proteobacteria,2U6EC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
SHD3_k127_366109_2	1121918.ARWE01000001_gene3081	2.104e-95	321.0	COG1013@1|root,COG1013@2|Bacteria,1MUY9@1224|Proteobacteria,42MQY@68525|delta/epsilon subdivisions,2WJGJ@28221|Deltaproteobacteria,43V7G@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	1.2.7.1,1.2.7.7	ko:K00170,ko:K00187	ko00010,ko00020,ko00280,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R07160,R08034,R08566,R08567	RC00004,RC00250,RC02742,RC02833,RC02856	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SHD3_k127_366109_1	1121918.ARWE01000001_gene3080	7.868e-105	353.0	COG0674@1|root,COG0674@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJG3@28221|Deltaproteobacteria,43TT3@69541|Desulfuromonadales	68525|delta/epsilon subdivisions	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.1	ko:K00169	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SHD3_k127_366109_0	1121918.ARWE01000001_gene3079	1.323e-163	544.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42P5P@68525|delta/epsilon subdivisions,2WITN@28221|Deltaproteobacteria,43TQJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	HI0933-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_9,Pyr_redox_2
SHD3_k127_366109_3	316274.Haur_3461	4.791e-70	256.0	COG3866@1|root,COG5297@1|root,COG3866@2|Bacteria,COG5297@2|Bacteria,2G8UB@200795|Chloroflexi	2|Bacteria	G	CBD_II	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	CBM_2,Glyco_hydro_12,Pec_lyase_C
SHD3_k127_366109_4	298653.Franean1_2092	2.091e-61	216.0	COG0448@1|root,COG0448@2|Bacteria,2I2EF@201174|Actinobacteria,4ERNH@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SHD3_k127_3662834_0	448385.sce3597	6.003e-204	650.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WJ88@28221|Deltaproteobacteria,2YTZW@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	ntrX	-	-	ko:K13599	ko02020,map02020	M00498	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_3662834_1	1254432.SCE1572_21770	3.595e-63	226.0	COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,42RV8@68525|delta/epsilon subdivisions,2WKU0@28221|Deltaproteobacteria,2YVHZ@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	bamD	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	YfiO
SHD3_k127_3662834_2	1192034.CAP_7926	3.72e-55	197.0	COG0782@1|root,COG0782@2|Bacteria,1RCXW@1224|Proteobacteria,42SDX@68525|delta/epsilon subdivisions,2WP41@28221|Deltaproteobacteria,2YV5G@29|Myxococcales	28221|Deltaproteobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
SHD3_k127_3662931_4	1192034.CAP_3855	1.899e-83	295.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_3855|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3662931_7	1254432.SCE1572_46755	2.844e-42	173.0	29RQC@1|root,30CTT@2|Bacteria,1QTPW@1224|Proteobacteria,435D4@68525|delta/epsilon subdivisions,2WZQP@28221|Deltaproteobacteria,2Z2IY@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SHD3_k127_3662931_3	1254432.SCE1572_23520	9.1e-87	294.0	COG0177@1|root,COG0177@2|Bacteria,1MUYQ@1224|Proteobacteria,42N6I@68525|delta/epsilon subdivisions,2WK7S@28221|Deltaproteobacteria,2Z2Z1@29|Myxococcales	28221|Deltaproteobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
SHD3_k127_3662931_0	1254432.SCE1572_22415	0.0	1147.0	COG0188@1|root,COG0188@2|Bacteria,1MUGG@1224|Proteobacteria,42KZ9@68525|delta/epsilon subdivisions,2WJBC@28221|Deltaproteobacteria,2YUDT@29|Myxococcales	28221|Deltaproteobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
SHD3_k127_3662931_2	1192034.CAP_7912	3.867e-95	319.0	COG2030@1|root,COG2030@2|Bacteria,1QXU8@1224|Proteobacteria,43C6S@68525|delta/epsilon subdivisions,2X7GZ@28221|Deltaproteobacteria,2YW6B@29|Myxococcales	28221|Deltaproteobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
SHD3_k127_3662931_1	1047013.AQSP01000142_gene127	2.387e-113	379.0	COG2070@1|root,COG2070@2|Bacteria,2NPGR@2323|unclassified Bacteria	2|Bacteria	S	Nitronate monooxygenase	fabK	-	1.3.1.9	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00083	R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	NMO,ThiG
SHD3_k127_3662931_6	391625.PPSIR1_04548	9.951e-71	246.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2YUT4@29|Myxococcales	28221|Deltaproteobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SHD3_k127_3662931_5	635013.TherJR_2074	2.006e-79	273.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,260VS@186807|Peptococcaceae	186801|Clostridia	IQ	PFAM short chain dehydrogenase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SHD3_k127_3662931_8	448385.sce5749	3.288e-08	61.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce5749|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SHD3_k127_3667472_2	1150626.PHAMO_280013	7.542e-74	251.0	COG1830@1|root,COG1830@2|Bacteria,1MWJW@1224|Proteobacteria,2U27K@28211|Alphaproteobacteria,2JUUK@204441|Rhodospirillales	204441|Rhodospirillales	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
SHD3_k127_3667472_0	335543.Sfum_2463	1.243e-140	462.0	COG1063@1|root,COG1063@2|Bacteria,1MV9A@1224|Proteobacteria,42SJQ@68525|delta/epsilon subdivisions,2WPH7@28221|Deltaproteobacteria,2MRF5@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
SHD3_k127_3667472_6	96561.Dole_1896	6.158e-17	86.0	COG0346@1|root,COG0346@2|Bacteria,1P708@1224|Proteobacteria,432H7@68525|delta/epsilon subdivisions,2WXRS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3667472_3	219305.MCAG_02521	2.638e-69	252.0	COG3386@1|root,COG3386@2|Bacteria,2HEMZ@201174|Actinobacteria,4DC5U@85008|Micromonosporales	201174|Actinobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
SHD3_k127_3667472_5	1120954.ATXE01000001_gene2185	1.869e-22	114.0	COG0739@1|root,COG4886@1|root,COG0739@2|Bacteria,COG4886@2|Bacteria,2I34T@201174|Actinobacteria,4DWIA@85009|Propionibacteriales	201174|Actinobacteria	M	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,VCBS
SHD3_k127_3667472_1	509191.AEDB02000089_gene3216	6.525e-124	415.0	COG5434@1|root,COG5434@2|Bacteria,1UQXS@1239|Firmicutes,258QV@186801|Clostridia,3WNDQ@541000|Ruminococcaceae	186801|Clostridia	M	Pectate lyase superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Pectate_lyase_3
SHD3_k127_3667472_7	338966.Ppro_0369	7.789e-06	49.0	COG3501@1|root,COG3501@2|Bacteria,1MU7Q@1224|Proteobacteria,42PYY@68525|delta/epsilon subdivisions,2WJID@28221|Deltaproteobacteria,43VNU@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Phage late control gene D protein (GPD)	-	-	-	-	-	-	-	-	-	-	-	-	Phage_GPD
SHD3_k127_3682668_5	215803.DB30_5820	2.708e-40	153.0	COG3189@1|root,COG3189@2|Bacteria,1Q9T3@1224|Proteobacteria,434KI@68525|delta/epsilon subdivisions,2WYXV@28221|Deltaproteobacteria,2Z0W0@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SHD3_k127_3682668_8	324057.Pjdr2_1772	3.215e-07	55.0	COG3669@1|root,COG3669@2|Bacteria,1TSG7@1239|Firmicutes,4HEKS@91061|Bacilli,26UH5@186822|Paenibacillaceae	91061|Bacilli	G	alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
SHD3_k127_3682668_0	760192.Halhy_5751	1.137e-136	451.0	2CK59@1|root,335GM@2|Bacteria,4NYUR@976|Bacteroidetes,1IWCN@117747|Sphingobacteriia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3682668_1	1173020.Cha6605_0968	7.136e-120	395.0	COG2267@1|root,COG2267@2|Bacteria,1G771@1117|Cyanobacteria	2|Bacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
SHD3_k127_3682668_7	67593.Physo135919	1.455e-11	78.0	COG0515@1|root,2QUN0@2759|Eukaryota,3Q8RR@4776|Peronosporales	4776|Peronosporales	KLT	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_3682668_4	720554.Clocl_2746	3.228e-49	196.0	COG3507@1|root,COG5520@1|root,COG3507@2|Bacteria,COG5520@2|Bacteria,1VV8A@1239|Firmicutes,250MI@186801|Clostridia	186801|Clostridia	M	Glycosyl hydrolase family 30 beta sandwich domain	-	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	Glyco_hydro_30,Glyco_hydro_30C
SHD3_k127_3682668_3	452637.Oter_2704	1.124e-63	226.0	COG4225@1|root,COG4225@2|Bacteria,46TG3@74201|Verrucomicrobia,3K902@414999|Opitutae	414999|Opitutae	S	PFAM glycosyl hydrolase family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	Glyco_hydro_88
SHD3_k127_3684558_11	1254432.SCE1572_12335	1.294e-34	145.0	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
SHD3_k127_3684558_13	1192034.CAP_7916	8.082e-21	103.0	COG4967@1|root,COG4967@2|Bacteria	2|Bacteria	NU	type IV pilus modification protein PilV	pilV-1	-	-	ko:K02671,ko:K02681	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
SHD3_k127_3684558_14	448385.sce2021	1.421e-19	100.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02246,ko:K08084	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.15.2	-	-	GspH,N_methyl
SHD3_k127_3684558_10	448385.sce2023	2.335e-35	151.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	ppiD	-	5.2.1.8	ko:K03769,ko:K03770,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
SHD3_k127_3684558_3	448385.sce2026	4.548e-157	517.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PP2C_2,Pkinase
SHD3_k127_3684558_5	1254432.SCE1572_12375	3.337e-79	274.0	COG1354@1|root,COG1354@2|Bacteria,1MVCN@1224|Proteobacteria,42RG5@68525|delta/epsilon subdivisions,2WNRE@28221|Deltaproteobacteria,2YV06@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
SHD3_k127_3684558_8	1254432.SCE1572_12385	1.988e-65	241.0	COG1386@1|root,COG5164@1|root,COG1386@2|Bacteria,COG5164@2|Bacteria,1PUA6@1224|Proteobacteria,42SVD@68525|delta/epsilon subdivisions,2WPFX@28221|Deltaproteobacteria,2Z049@29|Myxococcales	28221|Deltaproteobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
SHD3_k127_3684558_7	448385.sce2030	1.755e-65	243.0	2BQPR@1|root,32JK6@2|Bacteria,1PDCX@1224|Proteobacteria,435G0@68525|delta/epsilon subdivisions,2WZTH@28221|Deltaproteobacteria,2Z2QA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3684558_9	1144275.COCOR_06209	8.504e-60	221.0	COG1716@1|root,COG1716@2|Bacteria,1REM9@1224|Proteobacteria,43232@68525|delta/epsilon subdivisions,2WWVT@28221|Deltaproteobacteria,2YZXE@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_3684558_2	448385.sce5061	9.379e-208	660.0	COG0493@1|root,COG0493@2|Bacteria,1MU2H@1224|Proteobacteria,42MGY@68525|delta/epsilon subdivisions,2WJZJ@28221|Deltaproteobacteria,2Z2XA@29|Myxococcales	28221|Deltaproteobacteria	C	Glutamate synthase	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
SHD3_k127_3684558_0	1254432.SCE1572_30760	0.0	2325.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria,2YUAD@29|Myxococcales	28221|Deltaproteobacteria	E	Glutamate synthase	gltB1	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
SHD3_k127_3684558_6	448385.sce9205	3.039e-77	273.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce9205|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SHD3_k127_3684558_1	56110.Oscil6304_4395	1.217e-265	831.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1G1HW@1117|Cyanobacteria,1H6Y0@1150|Oscillatoriales	1117|Cyanobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
SHD3_k127_3700459_7	247639.MGP2080_12195	1.751e-13	81.0	COG1663@1|root,COG1663@2|Bacteria,1MU8G@1224|Proteobacteria,1RMMW@1236|Gammaproteobacteria,1J5MP@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	F	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	iBWG_1329.BWG_0767,iECDH10B_1368.ECDH10B_0985,iPC815.YPO1396	LpxK
SHD3_k127_3700459_5	448385.sce1622	3.567e-41	155.0	2A21P@1|root,30QBQ@2|Bacteria,1Q2MF@1224|Proteobacteria,43882@68525|delta/epsilon subdivisions,2X3HT@28221|Deltaproteobacteria,2YW5S@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3700459_1	1254432.SCE1572_02445	2.658e-95	329.0	COG1652@1|root,COG1652@2|Bacteria,1MUBV@1224|Proteobacteria,42QS9@68525|delta/epsilon subdivisions,2WN3H@28221|Deltaproteobacteria,2YVFR@29|Myxococcales	28221|Deltaproteobacteria	S	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
SHD3_k127_3700459_2	1192034.CAP_7201	1.286e-90	306.0	COG1183@1|root,COG1183@2|Bacteria,1MWD9@1224|Proteobacteria,42QV4@68525|delta/epsilon subdivisions,2WMR6@28221|Deltaproteobacteria,2YVVU@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pssA	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
SHD3_k127_3700459_0	448385.sce6528	1.13e-224	716.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42M2A@68525|delta/epsilon subdivisions,2WIJY@28221|Deltaproteobacteria,2YUEB@29|Myxococcales	28221|Deltaproteobacteria	S	ATPase components of ABC transporters with duplicated ATPase domains	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
SHD3_k127_3700459_4	448385.sce6529	1.384e-46	190.0	COG0695@1|root,COG0695@2|Bacteria,1PPNM@1224|Proteobacteria,437CJ@68525|delta/epsilon subdivisions,2X2I6@28221|Deltaproteobacteria,2Z2DY@29|Myxococcales	28221|Deltaproteobacteria	O	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SHD3_k127_3700459_3	1254432.SCE1572_06465	1.632e-51	192.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1PFJ9@1224|Proteobacteria,4372P@68525|delta/epsilon subdivisions,2X9PH@28221|Deltaproteobacteria,2YZFP@29|Myxococcales	28221|Deltaproteobacteria	KLT	SMART serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Pkinase
SHD3_k127_3700459_8	84751.XP_007882496.1	5.298e-09	68.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38DMI@33154|Opisthokonta,3PF4P@4751|Fungi,3V643@5204|Basidiomycota	4751|Fungi	T	Si dkey-21a6.5	-	-	-	-	-	-	-	-	-	-	-	-	Ephrin_rec_like
SHD3_k127_3702964_2	491915.Aflv_2512	4.127e-06	58.0	COG3209@1|root,COG3209@2|Bacteria,1TR8F@1239|Firmicutes,4HBZE@91061|Bacilli,21W5B@150247|Anoxybacillus	91061|Bacilli	M	RHS Repeat	wapA	GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	RHS_repeat
SHD3_k127_3702964_0	1121920.AUAU01000007_gene403	1.271e-110	365.0	COG1741@1|root,COG1741@2|Bacteria,3Y831@57723|Acidobacteria	57723|Acidobacteria	S	Pirin C-terminal cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Pirin,Pirin_C
SHD3_k127_3702964_1	880073.Calab_0035	1.239e-21	111.0	COG2911@1|root,COG4733@1|root,COG2911@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FlgD_ig,SLH
SHD3_k127_3706259_0	573413.Spirs_3564	2.409e-150	485.0	COG0205@1|root,COG0205@2|Bacteria,2J7BI@203691|Spirochaetes	203691|Spirochaetes	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SHD3_k127_3706259_3	290397.Adeh_3956	5.803e-37	150.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3706259_6	448385.sce0618	6.096e-11	69.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	bscD	-	-	ko:K03220	-	M00332	-	-	ko00000,ko00002,ko02044	3.A.6.1	-	-	FHA
SHD3_k127_3706259_10	608506.COB47_0986	1.538e-05	55.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,248NM@186801|Clostridia,42HXG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3706259_11	649639.Bcell_0870	4.708e-05	49.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,4HTI7@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3706259_13	632518.Calow_1346	0.0001746	44.0	arCOG07336@1|root,2Z8ST@2|Bacteria,1TRXN@1239|Firmicutes,248NM@186801|Clostridia,42HXG@68295|Thermoanaerobacterales	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3706259_7	515635.Dtur_0653	7.705e-09	61.0	arCOG07336@1|root,2Z8ST@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3706259_2	1254432.SCE1572_17195	4.755e-37	149.0	29WVW@1|root,30IHH@2|Bacteria,1PZ6T@1224|Proteobacteria,435EN@68525|delta/epsilon subdivisions,2WZSA@28221|Deltaproteobacteria,2Z2MZ@29|Myxococcales	28221|Deltaproteobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
SHD3_k127_3706259_4	765420.OSCT_0513	1.063e-33	144.0	COG1408@1|root,COG1408@2|Bacteria,2G6VC@200795|Chloroflexi,375MG@32061|Chloroflexia	32061|Chloroflexia	S	PFAM metallophosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos,Metallophos_2
SHD3_k127_3706259_5	309807.SRU_2757	5.904e-11	68.0	COG1595@1|root,COG1595@2|Bacteria,4NSVA@976|Bacteroidetes	976|Bacteroidetes	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3706259_1	1192034.CAP_1200	2.559e-56	215.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_1200|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3706259_12	1248916.ANFY01000007_gene2549	7.884e-05	45.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2U5BS@28211|Alphaproteobacteria,2K4S9@204457|Sphingomonadales	204457|Sphingomonadales	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SHD3_k127_3707074_1	234267.Acid_0207	2.665e-107	355.0	COG0583@1|root,COG0583@2|Bacteria,3Y34A@57723|Acidobacteria	57723|Acidobacteria	K	LysR substrate binding domain	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SHD3_k127_3707074_3	522306.CAP2UW1_2179	3.227e-18	89.0	COG1544@1|root,COG1544@2|Bacteria,1N8CQ@1224|Proteobacteria,2VVX7@28216|Betaproteobacteria	28216|Betaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_S30AE
SHD3_k127_3707074_0	1121920.AUAU01000004_gene849	9.175e-114	375.0	COG0861@1|root,COG0861@2|Bacteria,3Y37C@57723|Acidobacteria	57723|Acidobacteria	P	PFAM Integral membrane protein TerC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SHD3_k127_3707074_2	448385.sce5601	1.549e-19	99.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce5601|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3715539_5	35754.JNYJ01000052_gene6662	1.024e-90	310.0	COG3779@1|root,COG3779@2|Bacteria	2|Bacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF4261
SHD3_k127_3715539_6	1278073.MYSTI_05411	1.201e-62	234.0	COG5078@1|root,COG5078@2|Bacteria,1P62E@1224|Proteobacteria,432N1@68525|delta/epsilon subdivisions,2WY4Y@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	PFAM Ubiquitin-conjugating	-	-	-	-	-	-	-	-	-	-	-	-	UQ_con
SHD3_k127_3715539_7	1278073.MYSTI_05410	7.759e-60	228.0	COG0265@1|root,COG0265@2|Bacteria,1P00D@1224|Proteobacteria,431TG@68525|delta/epsilon subdivisions,2WWC8@28221|Deltaproteobacteria,2Z2GR@29|Myxococcales	28221|Deltaproteobacteria	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SHD3_k127_3715539_2	1278073.MYSTI_05408	3.146e-124	412.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	Yop-YscD_cpl
SHD3_k127_3715539_4	1278073.MYSTI_05407	6.606e-92	314.0	COG1310@1|root,COG1310@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	JAB
SHD3_k127_3715539_0	1278073.MYSTI_05406	8.274e-161	514.0	COG0476@1|root,COG0476@2|Bacteria	2|Bacteria	H	Involved in molybdopterin and thiamine biosynthesis, family 2	moeB	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF
SHD3_k127_3715539_9	1278073.MYSTI_05405	8.41e-41	154.0	2EFHE@1|root,3399Z@2|Bacteria	2|Bacteria	S	WXG100 protein secretion system (Wss), protein YukD	-	-	-	-	-	-	-	-	-	-	-	-	YukD
SHD3_k127_3715539_15	1303518.CCALI_00694	6.541e-06	53.0	COG0457@1|root,COG0457@2|Bacteria	1303518.CCALI_00694|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3715539_1	1242864.D187_003232	3.924e-142	479.0	COG1864@1|root,COG3591@1|root,COG1864@2|Bacteria,COG3591@2|Bacteria,1QSGF@1224|Proteobacteria	1224|Proteobacteria	L	DNA RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_NS,Trypsin_2
SHD3_k127_3715539_13	400682.PAC_15723879	3.175e-10	70.0	28IH4@1|root,2SFJ8@2759|Eukaryota,3A80Q@33154|Opisthokonta	33154|Opisthokonta	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3715539_10	448385.sce1472	1.728e-37	147.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X7DF@28221|Deltaproteobacteria,2YY2W@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_3715539_12	159087.Daro_3403	2.62e-10	65.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,2VNYV@28216|Betaproteobacteria,2KV5E@206389|Rhodocyclales	206389|Rhodocyclales	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_3715539_3	903818.KI912268_gene1425	8.906e-121	406.0	COG4191@1|root,COG4191@2|Bacteria,3Y2IQ@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SHD3_k127_3715539_11	1317118.ATO8_09046	4.39e-12	73.0	COG4978@1|root,COG4978@2|Bacteria	2|Bacteria	-	-	MA20_43725	-	-	ko:K13652	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,Polyketide_cyc2
SHD3_k127_3732034_1	525897.Dbac_1052	6.154e-90	309.0	COG0420@1|root,COG0420@2|Bacteria,1MXMJ@1224|Proteobacteria,42Q5U@68525|delta/epsilon subdivisions,2WINF@28221|Deltaproteobacteria,2M8J4@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	PFAM Metallophosphoesterase	sbcD-1	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
SHD3_k127_3732034_0	404589.Anae109_2985	1.355e-121	405.0	COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,42PQH@68525|delta/epsilon subdivisions,2WM5W@28221|Deltaproteobacteria,2YWUY@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
SHD3_k127_3732034_3	1304880.JAGB01000003_gene1025	3.564e-81	283.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
SHD3_k127_3732034_6	448385.sce3418	6.207e-06	58.0	2BPY0@1|root,32IRR@2|Bacteria,1Q1YS@1224|Proteobacteria,437KR@68525|delta/epsilon subdivisions,2X2UV@28221|Deltaproteobacteria,2YUI3@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3732034_2	338963.Pcar_2474	2.041e-85	295.0	COG3287@1|root,COG3287@2|Bacteria,1MVUZ@1224|Proteobacteria,42TFQ@68525|delta/epsilon subdivisions,2WPIZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	FIST N domain	-	-	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SHD3_k127_3732034_5	338966.Ppro_2992	4.986e-07	53.0	COG3287@1|root,COG3287@2|Bacteria	2|Bacteria	M	FIST C domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,FIST,FIST_C,GGDEF,PAS_9,PDZ_2,Pkinase
SHD3_k127_3732034_4	1303518.CCALI_02044	2.293e-53	196.0	2EE91@1|root,3383F@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3742306_12	1499967.BAYZ01000190_gene3861	2.988e-21	103.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
SHD3_k127_3742306_4	709986.Deima_0762	2.021e-120	401.0	COG0667@1|root,COG0667@2|Bacteria,1WMBT@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COGs COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase)	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SHD3_k127_3742306_11	1121127.JAFA01000015_gene6335	1.231e-25	119.0	COG0625@1|root,COG0625@2|Bacteria,1RAIN@1224|Proteobacteria,2VKU4@28216|Betaproteobacteria,1K2UR@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Belongs to the GST superfamily	-	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C,GST_C_3,GST_N
SHD3_k127_3742306_0	1254432.SCE1572_51765	9.72e-188	605.0	COG1414@1|root,COG1414@2|Bacteria,1Q48S@1224|Proteobacteria,42YKZ@68525|delta/epsilon subdivisions,2WUID@28221|Deltaproteobacteria,2YW86@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SHD3_k127_3742306_8	448385.sce0748	1.184e-60	222.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2Z1F1@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_3742306_13	1192034.CAP_3958	2.739e-15	89.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3742306_9	105559.Nwat_1044	6.826e-52	200.0	COG3115@1|root,COG3115@2|Bacteria,1QW35@1224|Proteobacteria	1224|Proteobacteria	D	cell septum assembly	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3742306_1	1192034.CAP_0942	2.249e-161	541.0	COG1073@1|root,COG1073@2|Bacteria,1QRTY@1224|Proteobacteria,433U7@68525|delta/epsilon subdivisions,2X3GS@28221|Deltaproteobacteria,2YW15@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3742306_15	134676.ACPL_4778	2.378e-08	67.0	COG3021@1|root,COG3534@1|root,COG3021@2|Bacteria,COG3534@2|Bacteria,2I58F@201174|Actinobacteria,4DJCZ@85008|Micromonosporales	201174|Actinobacteria	G	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SHD3_k127_3742306_16	153721.MYP_4620	1.645e-07	62.0	2EKCZ@1|root,33E39@2|Bacteria,4NXWT@976|Bacteroidetes,47VYQ@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3742306_2	661478.OP10G_4440	2.25e-147	490.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_2_N,SASA
SHD3_k127_3742306_5	215803.DB30_5827	5.005e-91	306.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,430ZU@68525|delta/epsilon subdivisions,2WWJB@28221|Deltaproteobacteria,2YV8T@29|Myxococcales	28221|Deltaproteobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SHD3_k127_3742306_7	1123242.JH636435_gene1244	3.082e-62	228.0	COG4850@1|root,COG4850@2|Bacteria,2IZDS@203682|Planctomycetes	203682|Planctomycetes	S	Uncharacterized conserved protein (DUF2183)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2183
SHD3_k127_3742306_10	1283284.AZUK01000001_gene2516	2.46e-40	171.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,1RM8A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	T	Diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,EAL,GAF_2,GGDEF,PAS,PAS_4,PAS_9
SHD3_k127_3742306_3	338966.Ppro_2725	5.034e-132	445.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43BSB@68525|delta/epsilon subdivisions,2X735@28221|Deltaproteobacteria,43TD7@69541|Desulfuromonadales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,SBP_bac_3
SHD3_k127_3742306_6	1415778.JQMM01000001_gene2127	1.451e-88	317.0	COG3437@1|root,COG4191@1|root,COG3437@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,1RP53@1236|Gammaproteobacteria,1J53Q@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HAMP,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_3753327_6	1192034.CAP_6527	1.169e-22	98.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YTXZ@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SHD3_k127_3753327_3	1192034.CAP_6527	7.945e-44	167.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YTXZ@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	nuoM	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
SHD3_k127_3753327_0	1192034.CAP_6528	4.767e-240	769.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,42KZE@68525|delta/epsilon subdivisions,2WIPT@28221|Deltaproteobacteria,2YWE3@29|Myxococcales	28221|Deltaproteobacteria	CP	NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein	nuoL-1	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_C,Proton_antipo_M,Proton_antipo_N
SHD3_k127_3753327_5	1254432.SCE1572_25610	3.998e-25	109.0	COG0713@1|root,COG0713@2|Bacteria,1RH0S@1224|Proteobacteria,42VAT@68525|delta/epsilon subdivisions,2WRE5@28221|Deltaproteobacteria,2YVNJ@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
SHD3_k127_3753327_4	1192034.CAP_6530	1.161e-37	149.0	COG0839@1|root,COG0839@2|Bacteria,1PJW9@1224|Proteobacteria,42V0F@68525|delta/epsilon subdivisions,2WS8G@28221|Deltaproteobacteria,2Z2ZK@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	nuoJ	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
SHD3_k127_3753327_1	448385.sce4223	3.343e-192	608.0	COG1894@1|root,COG1894@2|Bacteria,1MV8F@1224|Proteobacteria,42N6N@68525|delta/epsilon subdivisions,2WJ1W@28221|Deltaproteobacteria,2YUFG@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoF-2	-	1.6.5.3	ko:K00334,ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S,SLBB
SHD3_k127_3753327_2	1192034.CAP_6532	1.924e-59	209.0	COG1905@1|root,COG1905@2|Bacteria,1MWS2@1224|Proteobacteria,42SRI@68525|delta/epsilon subdivisions,2WQ7W@28221|Deltaproteobacteria,2Z370@29|Myxococcales	28221|Deltaproteobacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SHD3_k127_3761098_1	903818.KI912268_gene2977	8.173e-43	174.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SHD3_k127_3761098_0	1254432.SCE1572_13020	1.169e-255	810.0	COG3533@1|root,COG3533@2|Bacteria,1MWEN@1224|Proteobacteria	1224|Proteobacteria	S	Protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
SHD3_k127_3773951_2	941449.dsx2_0537	9.524e-151	490.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,42MEA@68525|delta/epsilon subdivisions,2WIW6@28221|Deltaproteobacteria,2M8HN@213115|Desulfovibrionales	28221|Deltaproteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
SHD3_k127_3773951_5	404589.Anae109_3251	1.1e-111	363.0	COG0262@1|root,COG0262@2|Bacteria,1R5UU@1224|Proteobacteria,42SE7@68525|delta/epsilon subdivisions,2WPK7@28221|Deltaproteobacteria,2YVBX@29|Myxococcales	28221|Deltaproteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SHD3_k127_3773951_12	335543.Sfum_2364	6.239e-32	133.0	COG0484@1|root,COG0484@2|Bacteria,1N19U@1224|Proteobacteria,42TX7@68525|delta/epsilon subdivisions,2WQMA@28221|Deltaproteobacteria,2MSG9@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
SHD3_k127_3773951_10	1121405.dsmv_2692	7.642e-38	145.0	COG0071@1|root,COG0071@2|Bacteria,1NA27@1224|Proteobacteria,42VE3@68525|delta/epsilon subdivisions,2WR9Q@28221|Deltaproteobacteria,2MMAN@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SHD3_k127_3773951_11	335543.Sfum_2366	9.685e-36	141.0	COG0071@1|root,COG0071@2|Bacteria,1N7C7@1224|Proteobacteria,42U0T@68525|delta/epsilon subdivisions,2WQ88@28221|Deltaproteobacteria,2MS3K@213462|Syntrophobacterales	28221|Deltaproteobacteria	O	Belongs to the small heat shock protein (HSP20) family	-	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
SHD3_k127_3773951_15	391625.PPSIR1_27843	2.253e-25	123.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_3773951_18	448385.sce0364	6.767e-09	65.0	COG3031@1|root,COG3031@2|Bacteria,1RFDB@1224|Proteobacteria,42WP0@68525|delta/epsilon subdivisions	1224|Proteobacteria	U	General secretion pathway protein C	xcsC	-	-	ko:K02452	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	PDZ_2,T2SSC
SHD3_k127_3773951_1	1121946.AUAX01000029_gene1945	5.63e-153	492.0	COG3507@1|root,COG3507@2|Bacteria,2GNEY@201174|Actinobacteria,4DBQJ@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43,Ricin_B_lectin
SHD3_k127_3773951_16	448385.sce7410	4.961e-25	114.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,43A9U@68525|delta/epsilon subdivisions,2X244@28221|Deltaproteobacteria,2Z171@29|Myxococcales	28221|Deltaproteobacteria	S	Pfam:RRM_6	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SHD3_k127_3773951_20	378806.STAUR_6021	0.0003961	46.0	2AGWF@1|root,3174U@2|Bacteria,1PYDK@1224|Proteobacteria,435AC@68525|delta/epsilon subdivisions,2WZMD@28221|Deltaproteobacteria,2Z2DC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3773951_9	234267.Acid_5886	2.489e-64	239.0	COG1538@1|root,COG1538@2|Bacteria,3Y3KB@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SHD3_k127_3773951_0	234267.Acid_5518	0.0	1212.0	COG0841@1|root,COG0841@2|Bacteria,3Y478@57723|Acidobacteria	57723|Acidobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SHD3_k127_3773951_6	240015.ACP_1129	4.902e-98	341.0	COG0845@1|root,COG0845@2|Bacteria,3Y2U2@57723|Acidobacteria,2JMFW@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SHD3_k127_3773951_8	1040989.AWZU01000073_gene3947	7.579e-92	312.0	COG4275@1|root,COG4275@2|Bacteria,1MYDE@1224|Proteobacteria,2TV61@28211|Alphaproteobacteria,3K2CR@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Chromate resistance exported protein	-	-	-	-	-	-	-	-	-	-	-	-	Chrome_Resist
SHD3_k127_3773951_7	666685.R2APBS1_1301	2.617e-96	329.0	COG1388@1|root,COG1388@2|Bacteria,1MY1S@1224|Proteobacteria,1T8D6@1236|Gammaproteobacteria,1XAGQ@135614|Xanthomonadales	135614|Xanthomonadales	M	Domain of Unknown Function (DUF1259)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1529
SHD3_k127_3773951_3	1168034.FH5T_03280	6.232e-148	496.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	dppX	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SHD3_k127_3773951_4	1382306.JNIM01000001_gene1483	1.393e-146	475.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SHD3_k127_3773951_17	1410670.JHXF01000008_gene820	1.078e-18	97.0	COG0726@1|root,COG2382@1|root,COG3693@1|root,COG0726@2|Bacteria,COG2382@2|Bacteria,COG3693@2|Bacteria,1UHTC@1239|Firmicutes,25C2J@186801|Clostridia,3WSAR@541000|Ruminococcaceae	1239|Firmicutes	GP	Glycosyl hydrolase family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	CBM_4_9,CBM_6,Glyco_hydro_10,Glyco_hydro_11,Polysacc_deac_1
SHD3_k127_3773951_19	5786.XP_003288885.1	3.297e-08	67.0	28JEF@1|root,2S9SU@2759|Eukaryota,3X9TT@554915|Amoebozoa	2759|Eukaryota	S	Expansin-like protein	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	DPBB_1,Pollen_allerg_1
SHD3_k127_3779891_1	1121403.AUCV01000033_gene3626	2.892e-47	176.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,42MZC@68525|delta/epsilon subdivisions,2WKRK@28221|Deltaproteobacteria,2MIYS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3683)	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_10,Fer4_8
SHD3_k127_3779891_0	1192034.CAP_8668	6.338e-195	620.0	COG0364@1|root,COG0364@2|Bacteria,1MUN0@1224|Proteobacteria,42M0J@68525|delta/epsilon subdivisions,2WK1D@28221|Deltaproteobacteria,2YUFW@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
SHD3_k127_3779891_2	929712.KI912613_gene2814	8.349e-08	64.0	COG3429@1|root,COG3429@2|Bacteria,2HYJH@201174|Actinobacteria,4CPZH@84995|Rubrobacteria	84995|Rubrobacteria	G	Glucose-6-phosphate dehydrogenase subunit	-	-	-	-	-	-	-	-	-	-	-	-	OpcA_G6PD_assem
SHD3_k127_3779891_3	795797.C497_04872	4.097e-06	57.0	COG0628@1|root,arCOG02642@2157|Archaea,2XT00@28890|Euryarchaeota,23TDZ@183963|Halobacteria	183963|Halobacteria	S	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
SHD3_k127_3783063_0	448385.sce5034	8.81e-25	111.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3793380_7	926550.CLDAP_02020	2.044e-20	103.0	COG1520@1|root,COG1520@2|Bacteria,2G93W@200795|Chloroflexi	200795|Chloroflexi	S	Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SHD3_k127_3793380_6	1254432.SCE1572_05290	4.822e-24	114.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_binding_2,FTP,FlgD_ig,PPC,Peptidase_M4,Peptidase_M4_C,RicinB_lectin_2,SBBP,TIG,Trypsin,VCBS
SHD3_k127_3793380_1	443143.GM18_4316	1.445e-135	478.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
SHD3_k127_3793380_3	485916.Dtox_0537	2.455e-79	275.0	COG2020@1|root,COG2020@2|Bacteria,1V0PB@1239|Firmicutes,25CSA@186801|Clostridia	186801|Clostridia	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3793380_4	1121468.AUBR01000058_gene881	1.356e-60	220.0	COG0749@1|root,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,42FDS@68295|Thermoanaerobacterales	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SHD3_k127_3793380_0	1229780.BN381_150139	0.0	1047.0	COG0550@1|root,COG0550@2|Bacteria,2GJU7@201174|Actinobacteria,3UW7H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0009892,GO:0010605,GO:0016020,GO:0016853,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0040007,GO:0043086,GO:0043167,GO:0043169,GO:0044092,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060700,GO:0060701,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0140097	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
SHD3_k127_3793380_2	1279038.KB907337_gene238	1.691e-111	368.0	COG1235@1|root,COG1235@2|Bacteria,1NW4Z@1224|Proteobacteria,2U14Z@28211|Alphaproteobacteria,2JPB8@204441|Rhodospirillales	204441|Rhodospirillales	S	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SHD3_k127_3793380_5	1173027.Mic7113_3893	1.238e-59	221.0	COG0618@1|root,COG0618@2|Bacteria,1G12Y@1117|Cyanobacteria,1H759@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH
SHD3_k127_3793380_8	926569.ANT_03260	0.0001754	45.0	COG0028@1|root,COG0028@2|Bacteria,2G5Q7@200795|Chloroflexi	200795|Chloroflexi	H	Thiamine pyrophosphate protein TPP binding domain protein	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
SHD3_k127_3802793_3	1254432.SCE1572_45505	1.467e-59	209.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2YTW8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SHD3_k127_3802793_1	1254432.SCE1572_16105	4.7e-68	252.0	2ANE2@1|root,31DCP@2|Bacteria,1QAIW@1224|Proteobacteria,43E1I@68525|delta/epsilon subdivisions,2WZFD@28221|Deltaproteobacteria,2Z20M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3802793_2	1192034.CAP_1747	3.845e-65	243.0	COG3170@1|root,COG3170@2|Bacteria,1QX3V@1224|Proteobacteria,43BWB@68525|delta/epsilon subdivisions,2X773@28221|Deltaproteobacteria,2YVT2@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SHD3_k127_3804111_2	1128421.JAGA01000002_gene1496	1.295e-127	419.0	COG3875@1|root,COG3875@2|Bacteria	2|Bacteria	S	lactate racemase activity	-	-	5.1.2.1	ko:K22373	ko00620,map00620	-	R01450	RC00519	ko00000,ko00001,ko01000	-	-	-	DUF2088
SHD3_k127_3804111_3	57918.XP_004287282.1	4.676e-126	427.0	2CC3R@1|root,2QPVE@2759|Eukaryota,37PZF@33090|Viridiplantae,3G9WK@35493|Streptophyta,4JD4H@91835|fabids	35493|Streptophyta	S	galactinol--sucrose galactosyltransferase	-	-	2.4.1.82	ko:K06617	ko00052,map00052	-	R02411	RC00049,RC00059	ko00000,ko00001,ko01000	-	GH36	-	Raffinose_syn
SHD3_k127_3804111_5	309807.SRU_0281	1.041e-96	334.0	COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,1FK1J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Glycosyl transferases group 1	gmhA	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glyco_transf_5,Glycos_transf_1
SHD3_k127_3804111_8	1463825.JNXC01000003_gene3711	2.394e-30	140.0	COG3534@1|root,COG3534@2|Bacteria,2GMAK@201174|Actinobacteria,4E195@85010|Pseudonocardiales	201174|Actinobacteria	G	alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C,CBM_2,DUF5011,Glyco_hydro_30C,Glyco_hydro_79n,Laminin_G_3,fn3
SHD3_k127_3804111_7	1127134.NOCYR_2237	1.685e-35	150.0	COG4106@1|root,COG4106@2|Bacteria,2GJMG@201174|Actinobacteria,4FVN0@85025|Nocardiaceae	201174|Actinobacteria	S	Methyltransferase small domain	tam	-	2.1.1.144	ko:K00598	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_23,Methyltransf_25
SHD3_k127_3804111_1	639030.JHVA01000001_gene2577	2.609e-156	500.0	COG1793@1|root,COG1793@2|Bacteria,3Y45N@57723|Acidobacteria,2JIH0@204432|Acidobacteriia	204432|Acidobacteriia	L	ATP dependent DNA ligase C terminal region	-	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
SHD3_k127_3804111_0	1267533.KB906737_gene1874	2.34e-209	658.0	COG3285@1|root,COG3285@2|Bacteria,3Y715@57723|Acidobacteria,2JM5P@204432|Acidobacteriia	204432|Acidobacteriia	L	dna ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3804111_11	690850.Desaf_1545	3.256e-14	77.0	COG3370@1|root,COG3370@2|Bacteria,1N3DX@1224|Proteobacteria,42UA2@68525|delta/epsilon subdivisions,2WQ2I@28221|Deltaproteobacteria,2MCZA@213115|Desulfovibrionales	28221|Deltaproteobacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	DrsE
SHD3_k127_3804111_4	448385.sce9313	1.072e-98	326.0	COG4225@1|root,COG4225@2|Bacteria,1NIRN@1224|Proteobacteria	1224|Proteobacteria	S	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
SHD3_k127_3804111_6	448385.sce3398	1.883e-66	239.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3804111_9	448385.sce3319	2.572e-18	98.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_3804111_10	1173026.Glo7428_2883	3.354e-18	86.0	COG2730@1|root,COG2730@2|Bacteria,1G7EB@1117|Cyanobacteria	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_3804111_12	1121035.AUCH01000016_gene2176	1.477e-06	56.0	2A2TX@1|root,30R7T@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3829)	yiiG	-	-	-	-	-	-	-	-	-	-	-	DUF3829
SHD3_k127_3810780_4	1254432.SCE1572_21985	5.074e-58	209.0	COG1595@1|root,COG1595@2|Bacteria,1NY42@1224|Proteobacteria,431SP@68525|delta/epsilon subdivisions,2WW84@28221|Deltaproteobacteria,2Z1C0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3810780_1	1125863.JAFN01000001_gene207	1.162e-89	303.0	COG1028@1|root,COG1028@2|Bacteria,1QXA0@1224|Proteobacteria,42UQH@68525|delta/epsilon subdivisions,2WQ5R@28221|Deltaproteobacteria	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
SHD3_k127_3810780_0	1192034.CAP_4459	2.687e-125	419.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,433VW@68525|delta/epsilon subdivisions,2X3QK@28221|Deltaproteobacteria,2YWUN@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_3810780_3	448385.sce3638	9.25e-68	237.0	COG1520@1|root,COG1520@2|Bacteria,1Q3BK@1224|Proteobacteria,4392T@68525|delta/epsilon subdivisions,2X48J@28221|Deltaproteobacteria,2YYHQ@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SHD3_k127_381130_9	411473.RUMCAL_02174	3.722e-32	130.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24J98@186801|Clostridia,3WJY6@541000|Ruminococcaceae	186801|Clostridia	S	TIGRFAM C_GCAxxG_C_C family	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
SHD3_k127_381130_3	1121342.AUCO01000003_gene1441	2.325e-118	385.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,36EYI@31979|Clostridiaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
SHD3_k127_381130_2	272562.CA_C2564	1.67e-182	574.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,36FFQ@31979|Clostridiaceae	186801|Clostridia	S	GGGtGRT protein	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
SHD3_k127_381130_16	1183438.GKIL_2036	0.000178	53.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SHD3_k127_381130_12	1298858.AUEL01000001_gene4673	3.789e-12	78.0	COG0845@1|root,COG0845@2|Bacteria,1P540@1224|Proteobacteria,2U20J@28211|Alphaproteobacteria,43N2H@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	M	HlyD membrane-fusion protein of T1SS	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3,HlyD_D23
SHD3_k127_381130_0	215803.DB30_8886	9.711e-218	711.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,43C3Q@68525|delta/epsilon subdivisions	1224|Proteobacteria	V	AcrB/AcrD/AcrF family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	-	ACR_tran
SHD3_k127_381130_14	219305.MCAG_04172	4.468e-10	68.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,CHAT,HTH_31,N_BRCA1_IG,TIR_2
SHD3_k127_381130_4	1121895.Q765_02105	1.289e-106	362.0	COG3659@1|root,COG3659@2|Bacteria,4NHN1@976|Bacteroidetes,1I7GH@117743|Flavobacteriia,2NVH9@237|Flavobacterium	976|Bacteroidetes	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K16080	-	-	-	-	ko00000,ko02000	1.B.4.2.2	-	-	OprB
SHD3_k127_381130_8	290397.Adeh_3806	4.49e-42	168.0	COG0735@1|root,COG0735@2|Bacteria,1QI59@1224|Proteobacteria,434TD@68525|delta/epsilon subdivisions,2WZ4D@28221|Deltaproteobacteria,2Z1B0@29|Myxococcales	28221|Deltaproteobacteria	K	Ferric uptake regulator family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
SHD3_k127_381130_13	502025.Hoch_2029	2.72e-11	68.0	2BR48@1|root,32K27@2|Bacteria,1Q2KM@1224|Proteobacteria,43878@68525|delta/epsilon subdivisions,2X3H6@28221|Deltaproteobacteria,2YW2M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_381130_1	1125863.JAFN01000001_gene2640	1.2e-200	647.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
SHD3_k127_381130_10	1089553.Tph_c04540	1.663e-20	98.0	COG1918@1|root,COG1918@2|Bacteria,1VMJD@1239|Firmicutes,24VI7@186801|Clostridia,42HGN@68295|Thermoanaerobacterales	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
SHD3_k127_381130_11	46234.ANA_C12479	9.124e-17	82.0	COG2002@1|root,COG2002@2|Bacteria,1G926@1117|Cyanobacteria	1117|Cyanobacteria	K	SpoVT AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
SHD3_k127_381130_6	903818.KI912269_gene26	8.017e-57	201.0	COG1487@1|root,COG1487@2|Bacteria,3Y87Z@57723|Acidobacteria	57723|Acidobacteria	S	ribonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_381130_5	1294142.CINTURNW_3524	4.073e-64	234.0	COG2020@1|root,COG2020@2|Bacteria,1UXZ3@1239|Firmicutes,24T5J@186801|Clostridia,36N3W@31979|Clostridiaceae	186801|Clostridia	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SHD3_k127_381130_7	1408422.JHYF01000008_gene3696	4.415e-47	177.0	COG1309@1|root,COG1309@2|Bacteria,1V3YX@1239|Firmicutes,24Q7E@186801|Clostridia,36PSC@31979|Clostridiaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_3819847_2	1123065.ATWL01000006_gene2307	3.062e-97	337.0	COG1082@1|root,COG1082@2|Bacteria,2I94Z@201174|Actinobacteria	201174|Actinobacteria	G	BNR repeat-containing family member	-	-	-	-	-	-	-	-	-	-	-	-	BNR_4
SHD3_k127_3819847_1	398512.JQKC01000004_gene5283	8.248e-109	370.0	COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,24BMN@186801|Clostridia,3WJP1@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
SHD3_k127_3819847_0	1120949.KB903297_gene5459	6.616e-182	586.0	COG1506@1|root,COG5297@1|root,COG1506@2|Bacteria,COG5297@2|Bacteria,2GNJM@201174|Actinobacteria,4DBDW@85008|Micromonosporales	201174|Actinobacteria	EG	CBD_II	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SHD3_k127_3819847_4	1254432.SCE1572_43485	7.004e-71	250.0	COG2755@1|root,COG5297@1|root,COG2755@2|Bacteria,COG5297@2|Bacteria,1PFIY@1224|Proteobacteria,434S6@68525|delta/epsilon subdivisions,2WZ38@28221|Deltaproteobacteria,2Z1QH@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_3819847_5	1192034.CAP_3356	1.508e-40	166.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_3356|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3819847_3	1192034.CAP_0441	2.42e-78	290.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_0441|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3819847_6	1192034.CAP_3350	5.315e-33	146.0	COG0683@1|root,COG0683@2|Bacteria,1MWJ1@1224|Proteobacteria,42UMR@68525|delta/epsilon subdivisions,2WQ71@28221|Deltaproteobacteria,2YVN1@29|Myxococcales	28221|Deltaproteobacteria	E	Periplasmic binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SHD3_k127_3831297_5	1192034.CAP_7623	2.24e-71	254.0	2BBR2@1|root,32597@2|Bacteria,1QAQN@1224|Proteobacteria,43E36@68525|delta/epsilon subdivisions,2WZJR@28221|Deltaproteobacteria,2Z2A1@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3831297_6	1192034.CAP_7624	8.168e-63	233.0	COG0564@1|root,COG0564@2|Bacteria,1MUBN@1224|Proteobacteria,42MBA@68525|delta/epsilon subdivisions,2WKX9@28221|Deltaproteobacteria,2YUX4@29|Myxococcales	28221|Deltaproteobacteria	J	Responsible for synthesis of pseudouridine from uracil	coaE	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	CoaE,PseudoU_synth_2,S4
SHD3_k127_3831297_0	1254432.SCE1572_51290	2.579e-316	980.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria,2YUEK@29|Myxococcales	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SHD3_k127_3831297_17	1254432.SCE1572_50475	0.0001138	53.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SHD3_k127_3831297_2	448385.sce3438	3.04e-86	297.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_3831297_8	357808.RoseRS_3811	4.265e-49	184.0	COG2518@1|root,COG2518@2|Bacteria,2G6NG@200795|Chloroflexi,377B2@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins	pcm	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	PCMT
SHD3_k127_3831297_12	404589.Anae109_0457	1.676e-39	153.0	COG1678@1|root,COG1678@2|Bacteria,1RCXM@1224|Proteobacteria,42SD7@68525|delta/epsilon subdivisions,2WPI5@28221|Deltaproteobacteria,2YVK5@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the UPF0301 (AlgH) family	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
SHD3_k127_3831297_4	290397.Adeh_2594	7.108e-80	275.0	COG1355@1|root,COG1355@2|Bacteria,1MXK5@1224|Proteobacteria,42R55@68525|delta/epsilon subdivisions,2WN4E@28221|Deltaproteobacteria,2Z304@29|Myxococcales	28221|Deltaproteobacteria	S	Memo-like protein	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	Memo
SHD3_k127_3831297_7	1403819.BATR01000104_gene3621	2.787e-54	203.0	COG2207@1|root,COG2207@2|Bacteria,46UPM@74201|Verrucomicrobia,2IUQC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
SHD3_k127_3831297_15	398767.Glov_0642	3.333e-17	96.0	COG4733@1|root,COG4733@2|Bacteria,1N010@1224|Proteobacteria,42M7U@68525|delta/epsilon subdivisions,2WRUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	PFAM Fibronectin, type III domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
SHD3_k127_3831297_1	665571.STHERM_c01940	2.31e-115	389.0	COG0460@1|root,COG0460@2|Bacteria,2J89J@203691|Spirochaetes	203691|Spirochaetes	E	homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
SHD3_k127_3831297_11	643562.Daes_2693	5.159e-40	158.0	COG1971@1|root,COG1971@2|Bacteria,1NWBY@1224|Proteobacteria,42RE2@68525|delta/epsilon subdivisions,2WNEN@28221|Deltaproteobacteria,2MB2K@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
SHD3_k127_3831297_9	448385.sce6926	1.295e-40	164.0	2E2XW@1|root,32XYS@2|Bacteria,1N3ID@1224|Proteobacteria,42UFM@68525|delta/epsilon subdivisions,2WQKF@28221|Deltaproteobacteria,2YVPU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3831297_13	448385.sce0412	5.805e-24	103.0	COG0745@1|root,COG3437@1|root,COG3667@1|root,COG0745@2|Bacteria,COG3437@2|Bacteria,COG3667@2|Bacteria,1QXU5@1224|Proteobacteria,43C6N@68525|delta/epsilon subdivisions,2X7GW@28221|Deltaproteobacteria,2YUUA@29|Myxococcales	28221|Deltaproteobacteria	T	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,HD_5,Response_reg,T2SSE_N
SHD3_k127_3836270_0	330214.NIDE0726	2.993e-305	968.0	COG0841@1|root,COG0841@2|Bacteria,3J0ZG@40117|Nitrospirae	40117|Nitrospirae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
SHD3_k127_3836270_3	797114.C475_00767	1.57e-12	79.0	arCOG03858@1|root,arCOG03858@2157|Archaea,2XX40@28890|Euryarchaeota,23VUT@183963|Halobacteria	183963|Halobacteria	G	Glycosyl hydrolase family 12	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_12
SHD3_k127_3836270_1	1487953.JMKF01000065_gene4631	3.505e-87	295.0	COG1215@1|root,COG1215@2|Bacteria,1GHF8@1117|Cyanobacteria,1H7FV@1150|Oscillatoriales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_3836270_4	326427.Cagg_0457	5.761e-08	66.0	COG1287@1|root,COG1287@2|Bacteria,2GA02@200795|Chloroflexi,377K4@32061|Chloroflexia	32061|Chloroflexia	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3839210_3	103733.JNYO01000039_gene4515	2.49e-08	68.0	295DP@1|root,2ZSRJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3839210_2	391625.PPSIR1_38806	9.114e-29	135.0	2AN2E@1|root,31CZZ@2|Bacteria,1QA0W@1224|Proteobacteria,434RF@68525|delta/epsilon subdivisions,2WZ2M@28221|Deltaproteobacteria,2Z16X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11
SHD3_k127_3839210_0	1232410.KI421421_gene3608	1.929e-85	301.0	COG0526@1|root,COG0526@2|Bacteria,1MWDE@1224|Proteobacteria,42RCT@68525|delta/epsilon subdivisions,2WKJ9@28221|Deltaproteobacteria,43UJX@69541|Desulfuromonadales	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Glutaredoxin
SHD3_k127_3839210_1	1254432.SCE1572_45365	4.981e-74	265.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	DNase-RNase,PDZ_2,Trypsin_2
SHD3_k127_3839210_4	378806.STAUR_0754	1.057e-07	63.0	2EIZM@1|root,33CQT@2|Bacteria,1P1YR@1224|Proteobacteria,439UY@68525|delta/epsilon subdivisions,2X58M@28221|Deltaproteobacteria,2Z09N@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3840859_0	344747.PM8797T_21498	1.383e-85	298.0	COG0515@1|root,COG0515@2|Bacteria,2IXG3@203682|Planctomycetes	203682|Planctomycetes	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	HDOD,Pkinase,dCache_1
SHD3_k127_3840859_2	1042375.AFPL01000029_gene3472	0.0007833	48.0	COG0501@1|root,COG0501@2|Bacteria,1R47C@1224|Proteobacteria,1RPRU@1236|Gammaproteobacteria,46BJ5@72275|Alteromonadaceae	1236|Gammaproteobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48,Pilin
SHD3_k127_3840859_1	448385.sce4005	1.57e-47	186.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,CelD_N,Glyco_hydro_11,Glyco_hydro_9,HemolysinCabind,Lipase_GDSL_2,Polysacc_deac_1,SASA
SHD3_k127_3844484_18	448385.sce0354	2.716e-13	83.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SHD3_k127_3844484_8	1254432.SCE1572_23655	1.696e-83	296.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3844484_14	1192034.CAP_7010	2.61e-29	136.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_16,TPR_19,TPR_7,TPR_8
SHD3_k127_3844484_0	391625.PPSIR1_29925	3.172e-247	785.0	COG5316@1|root,COG5316@2|Bacteria,1NWFX@1224|Proteobacteria,42NSK@68525|delta/epsilon subdivisions,2WMAZ@28221|Deltaproteobacteria,2YUUF@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
SHD3_k127_3844484_9	448385.sce4204	1.968e-77	272.0	COG0142@1|root,COG0142@2|Bacteria,1PIT3@1224|Proteobacteria,4354P@68525|delta/epsilon subdivisions,2X95E@28221|Deltaproteobacteria,2Z21G@29|Myxococcales	28221|Deltaproteobacteria	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
SHD3_k127_3844484_5	448385.sce1761	1.124e-120	402.0	COG1304@1|root,COG1304@2|Bacteria,1N6KI@1224|Proteobacteria,42TUC@68525|delta/epsilon subdivisions,2WQGC@28221|Deltaproteobacteria,2YUIJ@29|Myxococcales	28221|Deltaproteobacteria	C	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)	fni	-	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	-	FMN_dh
SHD3_k127_3844484_13	926569.ANT_28790	2.455e-41	156.0	COG1545@1|root,COG1545@2|Bacteria,2G73Z@200795|Chloroflexi	200795|Chloroflexi	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
SHD3_k127_3844484_3	926550.CLDAP_27990	2.862e-133	435.0	COG0183@1|root,COG0183@2|Bacteria,2G63J@200795|Chloroflexi	200795|Chloroflexi	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
SHD3_k127_3844484_1	926569.ANT_28810	2.03e-146	472.0	COG3425@1|root,COG3425@2|Bacteria,2G606@200795|Chloroflexi	200795|Chloroflexi	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein	-	-	2.3.3.10	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	M00088,M00095	R01978	RC00004,RC00503	ko00000,ko00001,ko00002,ko01000	-	-	-	ACP_syn_III_C
SHD3_k127_3844484_11	215803.DB30_4973	5.622e-66	238.0	COG1108@1|root,COG1108@2|Bacteria,1Q1G9@1224|Proteobacteria,4378R@68525|delta/epsilon subdivisions,2X2BN@28221|Deltaproteobacteria,2YX1Q@29|Myxococcales	28221|Deltaproteobacteria	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC-3
SHD3_k127_3844484_12	1297742.A176_07167	1.799e-57	208.0	COG1121@1|root,COG1121@2|Bacteria,1MUDW@1224|Proteobacteria,42NI8@68525|delta/epsilon subdivisions,2X2B5@28221|Deltaproteobacteria,2Z08Q@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SHD3_k127_3844484_7	1242864.D187_009011	1.027e-85	293.0	COG0803@1|root,COG0803@2|Bacteria,1MVW9@1224|Proteobacteria,42MBX@68525|delta/epsilon subdivisions,2WQ7S@28221|Deltaproteobacteria,2YTZ9@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the bacterial solute-binding protein 9 family	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
SHD3_k127_3844484_2	483219.LILAB_22490	1.165e-138	457.0	COG3170@1|root,COG3170@2|Bacteria,1QX7F@1224|Proteobacteria,42NQR@68525|delta/epsilon subdivisions,2WRZ7@28221|Deltaproteobacteria,2YYH9@29|Myxococcales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3844484_10	690850.Desaf_3380	2.585e-66	246.0	COG0500@1|root,COG0500@2|Bacteria,1QW86@1224|Proteobacteria,42N1Q@68525|delta/epsilon subdivisions,2WJJS@28221|Deltaproteobacteria,2MA1B@213115|Desulfovibrionales	28221|Deltaproteobacteria	Q	O-methyltransferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
SHD3_k127_3844484_16	1242864.D187_008996	1.007e-19	104.0	COG3411@1|root,COG3411@2|Bacteria,1RM68@1224|Proteobacteria,42TUK@68525|delta/epsilon subdivisions,2WQGU@28221|Deltaproteobacteria,2YVQK@29|Myxococcales	28221|Deltaproteobacteria	C	Ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3844484_6	316274.Haur_4064	1.823e-118	395.0	COG2189@1|root,COG2189@2|Bacteria,2G5WR@200795|Chloroflexi,376Z9@32061|Chloroflexia	32061|Chloroflexia	H	PFAM DNA methylase N-4 N-6 domain protein	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
SHD3_k127_3844484_4	290317.Cpha266_0514	4.749e-121	403.0	COG0477@1|root,COG0477@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SHD3_k127_3844484_17	1206720.BAFQ01000042_gene1036	6.865e-19	100.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4FVE3@85025|Nocardiaceae	201174|Actinobacteria	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
SHD3_k127_3844484_15	1254432.SCE1572_13870	7.608e-20	99.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3848854_20	1134445.AJJM01000030_gene4563	2.827e-05	55.0	COG1595@1|root,COG2340@1|root,COG1595@2|Bacteria,COG2340@2|Bacteria,2GJ21@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	CAP,Sigma70_r2
SHD3_k127_3848854_7	1254432.SCE1572_17135	1.015e-87	307.0	COG1656@1|root,COG1656@2|Bacteria,1QWEF@1224|Proteobacteria,42ZSC@68525|delta/epsilon subdivisions,2WUTP@28221|Deltaproteobacteria,2YURA@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4178)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4178
SHD3_k127_3848854_11	1379270.AUXF01000001_gene2345	1.064e-62	235.0	COG4262@1|root,COG4262@2|Bacteria,1ZU7C@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_3848854_10	502025.Hoch_4949	7.799e-63	223.0	COG0558@1|root,COG0558@2|Bacteria,1NJC1@1224|Proteobacteria,42XU7@68525|delta/epsilon subdivisions,2WT69@28221|Deltaproteobacteria,2Z0YR@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	-	-	-	-	-	-	-	-	-	-	CDP-OH_P_transf
SHD3_k127_3848854_0	290397.Adeh_2407	1.38e-183	602.0	COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,42M9S@68525|delta/epsilon subdivisions,2WJSZ@28221|Deltaproteobacteria,2YYKK@29|Myxococcales	28221|Deltaproteobacteria	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
SHD3_k127_3848854_14	1192034.CAP_3662	2.242e-48	188.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_3662|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3848854_5	448385.sce4512	1.298e-100	347.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3848854_16	448385.sce1849	1.521e-33	138.0	2AH4J@1|root,317E7@2|Bacteria,1PYQD@1224|Proteobacteria,435HH@68525|delta/epsilon subdivisions,2WZV3@28221|Deltaproteobacteria,2Z2TC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3848854_12	1192034.CAP_3662	1.101e-55	208.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_3662|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3848854_8	1254432.SCE1572_37985	5.769e-81	299.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3848854_6	1121438.JNJA01000019_gene2769	2.517e-89	301.0	COG0778@1|root,COG0778@2|Bacteria,1PUI1@1224|Proteobacteria,42P7Q@68525|delta/epsilon subdivisions,2WKSB@28221|Deltaproteobacteria,2M9QE@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SagB-type dehydrogenase domain	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SHD3_k127_3848854_4	1121920.AUAU01000005_gene1063	8.707e-106	357.0	COG0462@1|root,COG0462@2|Bacteria,3Y3KV@57723|Acidobacteria	57723|Acidobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
SHD3_k127_3848854_3	1120797.KB908267_gene3278	6.86e-107	377.0	COG2242@1|root,COG2242@2|Bacteria,2HN5V@201174|Actinobacteria,235WF@1762|Mycobacteriaceae	201174|Actinobacteria	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23,Methyltransf_25
SHD3_k127_3848854_21	1121382.JQKG01000001_gene2459	3.023e-05	57.0	COG2227@1|root,COG2227@2|Bacteria,1WK2D@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_3848854_18	1448389.BAVQ01000043_gene1922	7.965e-06	59.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria	201174|Actinobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_3848854_22	1192034.CAP_8992	0.0005321	52.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_3848854_19	7159.AAEL012909-PA	2.731e-05	51.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SQGI@50557|Insecta,4555M@7147|Diptera,45EMX@7148|Nematocera	33208|Metazoa	T	Calcium-binding EGF-like domain	-	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA,Zona_pellucida
SHD3_k127_3848854_13	266117.Rxyl_2842	5.447e-50	184.0	COG0590@1|root,COG0590@2|Bacteria,2I9KR@201174|Actinobacteria	201174|Actinobacteria	FJ	CMP dCMP deaminase, zinc-binding	-	-	-	-	-	-	-	-	-	-	-	-	dCMP_cyt_deam_1
SHD3_k127_3848854_2	1192034.CAP_5462	3.175e-109	370.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_3848854_1	502025.Hoch_2510	3.782e-171	549.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU4Y@29|Myxococcales	28221|Deltaproteobacteria	T	Two component, sigma54 specific, transcriptional regulator, Fis family	-	-	-	ko:K07712	ko02020,map02020	M00497	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_3848854_17	1192034.CAP_6502	3.092e-07	61.0	COG1470@1|root,COG1470@2|Bacteria,1Q9IM@1224|Proteobacteria,434EQ@68525|delta/epsilon subdivisions,2WYS3@28221|Deltaproteobacteria,2Z0GH@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SHD3_k127_3860265_3	1254432.SCE1572_12315	3.176e-38	159.0	COG0509@1|root,COG0509@2|Bacteria,1RGV7@1224|Proteobacteria,42RS9@68525|delta/epsilon subdivisions,2WP93@28221|Deltaproteobacteria,2Z1AT@29|Myxococcales	28221|Deltaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
SHD3_k127_3860265_1	1128421.JAGA01000002_gene782	1.143e-101	343.0	COG0404@1|root,COG0404@2|Bacteria,2NNSR@2323|unclassified Bacteria	2|Bacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
SHD3_k127_3860265_2	1192034.CAP_4564	2.59e-56	206.0	COG0745@1|root,COG0745@2|Bacteria	1192034.CAP_4564|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3860265_0	1192034.CAP_7919	1.455e-186	629.0	COG3419@1|root,COG3419@2|Bacteria,1NUAV@1224|Proteobacteria,42NJ7@68525|delta/epsilon subdivisions,2WJYB@28221|Deltaproteobacteria,2YW3S@29|Myxococcales	28221|Deltaproteobacteria	NU	Tfp pilus assembly protein tip-associated adhesin	-	-	-	ko:K02674	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	Neisseria_PilC
SHD3_k127_3860265_6	1254432.SCE1572_12335	3.972e-07	54.0	COG4966@1|root,COG4966@2|Bacteria	2|Bacteria	NU	pilus assembly protein PilW	-	-	-	ko:K02672	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	N_methyl
SHD3_k127_3885057_1	338966.Ppro_0904	1.296e-11	69.0	COG0784@1|root,COG5000@1|root,COG0784@2|Bacteria,COG5000@2|Bacteria,1NC9X@1224|Proteobacteria,43BSJ@68525|delta/epsilon subdivisions,2X73B@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,Response_reg
SHD3_k127_3885057_0	313596.RB2501_10772	1.439e-150	496.0	COG3119@1|root,COG3119@2|Bacteria,4NEPB@976|Bacteroidetes,1HYHN@117743|Flavobacteriia	976|Bacteroidetes	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SHD3_k127_3885730_1	521011.Mpal_1663	1.156e-25	109.0	COG0467@1|root,arCOG01174@2157|Archaea,2XV95@28890|Euryarchaeota,2N9UG@224756|Methanomicrobia	224756|Methanomicrobia	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SHD3_k127_3885730_0	1254432.SCE1572_27455	1.252e-142	472.0	COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BJQ@68525|delta/epsilon subdivisions,2X7N6@28221|Deltaproteobacteria,2Z2X1@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SHD3_k127_3891298_22	448385.sce4032	0.0004148	51.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_3891298_17	684949.ATTJ01000001_gene2317	5.667e-10	62.0	COG1826@1|root,COG1826@2|Bacteria,1WKBC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SHD3_k127_3891298_1	448385.sce0933	6.453e-244	765.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_3891298_13	448385.sce0942	9.205e-37	144.0	COG3339@1|root,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
SHD3_k127_3891298_8	1192034.CAP_0370	6.683e-73	258.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YXC1@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SHD3_k127_3891298_7	448385.sce0944	1.641e-77	273.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_3891298_12	404589.Anae109_2601	6.279e-57	203.0	COG1611@1|root,COG1611@2|Bacteria,1RD59@1224|Proteobacteria,42SVS@68525|delta/epsilon subdivisions,2WNMI@28221|Deltaproteobacteria,2YZY7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the LOG family	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
SHD3_k127_3891298_9	83332.Rv1732c	5.593e-70	246.0	COG1225@1|root,COG1225@2|Bacteria,2II4M@201174|Actinobacteria,234YH@1762|Mycobacteriaceae	201174|Actinobacteria	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
SHD3_k127_3891298_19	179408.Osc7112_2745	2.282e-06	55.0	COG2337@1|root,COG2337@2|Bacteria,1G5NV@1117|Cyanobacteria,1HHND@1150|Oscillatoriales	1117|Cyanobacteria	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SHD3_k127_3891298_5	1121396.KB892935_gene3851	7.037e-107	369.0	COG1032@1|root,COG1307@1|root,COG1461@1|root,COG1032@2|Bacteria,COG1307@2|Bacteria,COG1461@2|Bacteria,1MWR0@1224|Proteobacteria,439ZF@68525|delta/epsilon subdivisions,2WU71@28221|Deltaproteobacteria,2MN5E@213118|Desulfobacterales	28221|Deltaproteobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Dak2,DegV,Radical_SAM
SHD3_k127_3891298_15	1121403.AUCV01000014_gene4650	1.676e-21	102.0	COG2834@1|root,COG2834@2|Bacteria,1NDM6@1224|Proteobacteria,42VR3@68525|delta/epsilon subdivisions,2WRTR@28221|Deltaproteobacteria,2MM6C@213118|Desulfobacterales	28221|Deltaproteobacteria	M	Outer membrane lipoprotein carrier protein LolA	-	-	-	-	-	-	-	-	-	-	-	-	LolA
SHD3_k127_3891298_16	1121403.AUCV01000014_gene4649	1.701e-15	86.0	2FB0T@1|root,3437G@2|Bacteria,1P1GK@1224|Proteobacteria,431F1@68525|delta/epsilon subdivisions,2WWSI@28221|Deltaproteobacteria,2MNUW@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3891298_3	1167006.UWK_00151	2.51e-158	537.0	COG0500@1|root,COG4258@1|root,COG0500@2|Bacteria,COG4258@2|Bacteria,1MU1E@1224|Proteobacteria,42P70@68525|delta/epsilon subdivisions,2WJGD@28221|Deltaproteobacteria,2MJYG@213118|Desulfobacterales	28221|Deltaproteobacteria	Q	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SHD3_k127_3891298_21	691883.XP_009497501.1	3.356e-06	62.0	COG0515@1|root,COG1404@1|root,KOG0193@2759|Eukaryota,KOG3525@2759|Eukaryota,38EIV@33154|Opisthokonta	33154|Opisthokonta	OT	extracellular matrix	FRAS1	GO:0001655,GO:0001656,GO:0001822,GO:0002009,GO:0003338,GO:0005575,GO:0005576,GO:0005604,GO:0006810,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0015031,GO:0015833,GO:0030326,GO:0031012,GO:0032501,GO:0032502,GO:0033036,GO:0035107,GO:0035108,GO:0035113,GO:0042886,GO:0043588,GO:0044420,GO:0044421,GO:0045184,GO:0048513,GO:0048598,GO:0048729,GO:0048731,GO:0048736,GO:0048856,GO:0051179,GO:0051234,GO:0060021,GO:0060173,GO:0060429,GO:0060993,GO:0061618,GO:0062023,GO:0071702,GO:0071705,GO:0072001	-	ko:K17885	-	-	-	-	ko00000,ko02000,ko03029	2.A.29.25	-	-	Cadherin_3,Calx-beta,Pkinase,VWC
SHD3_k127_3891298_10	1254432.SCE1572_22990	6.022e-61	225.0	COG3628@1|root,COG3628@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3891298_6	1192034.CAP_1200	8.347e-85	298.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_1200|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3891298_11	1192034.CAP_1200	5.124e-59	221.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_1200|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3891298_20	1254432.SCE1572_44490	2.346e-06	54.0	2FIE8@1|root,34A6F@2|Bacteria,1P3KN@1224|Proteobacteria,431Y1@68525|delta/epsilon subdivisions,2WWQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4423
SHD3_k127_3891298_4	448385.sce0945	1.787e-138	475.0	COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,1MW2T@1224|Proteobacteria,42M1M@68525|delta/epsilon subdivisions,2WPBN@28221|Deltaproteobacteria,2Z2ZM@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	mltC	-	-	ko:K08306,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	DUF3393,SLT,TPR_6
SHD3_k127_3891298_0	1125863.JAFN01000001_gene353	0.0	1291.0	COG0458@1|root,COG0458@2|Bacteria,1MUDZ@1224|Proteobacteria,42MGK@68525|delta/epsilon subdivisions,2WJQH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Belongs to the CarB family	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
SHD3_k127_3891298_18	448385.sce2559	1.641e-07	63.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce2559|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3891298_2	1254432.SCE1572_50745	2.045e-171	559.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF4214,HYR,PD40,PKD,REJ
SHD3_k127_3901137_8	159450.NH14_06015	7.352e-14	78.0	COG0300@1|root,COG0300@2|Bacteria,1PNDU@1224|Proteobacteria,2VIWD@28216|Betaproteobacteria,1K056@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	wcbP	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_3901137_0	700598.Niako_5559	3.794e-94	317.0	COG3958@1|root,COG3958@2|Bacteria,4NFTS@976|Bacteroidetes	976|Bacteroidetes	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr
SHD3_k127_3901137_3	700598.Niako_5558	2.456e-78	271.0	COG3959@1|root,COG3959@2|Bacteria,4NDWK@976|Bacteroidetes,1IQSI@117747|Sphingobacteriia	976|Bacteroidetes	G	PFAM Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SHD3_k127_3901137_5	1125863.JAFN01000001_gene381	9.324e-40	168.0	COG2199@1|root,COG3706@2|Bacteria,1REEI@1224|Proteobacteria,42RTM@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	PFAM GGDEF domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HAMP
SHD3_k127_3901137_4	700598.Niako_0709	1.063e-69	258.0	COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,1IP52@117747|Sphingobacteriia	976|Bacteroidetes	G	Alpha-L-arabinofuranosidase domain protein	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
SHD3_k127_3901137_2	1214101.BN159_1639	1.806e-80	283.0	COG3250@1|root,COG5297@1|root,COG3250@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	AbfB,ArabFuran-catal
SHD3_k127_3901137_1	59374.Fisuc_2943	3.614e-85	301.0	COG5520@1|root,COG5520@2|Bacteria	59374.Fisuc_2943|-	M	Belongs to the glycosyl hydrolase 30 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3901137_9	1254432.SCE1572_02325	3.602e-10	70.0	2DK48@1|root,308EE@2|Bacteria,1QSG3@1224|Proteobacteria,4357G@68525|delta/epsilon subdivisions,2WZIH@28221|Deltaproteobacteria,2Z27V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3901137_6	1254432.SCE1572_02320	2.563e-33	136.0	COG1595@1|root,COG1595@2|Bacteria,1QR72@1224|Proteobacteria,43E0Y@68525|delta/epsilon subdivisions,2WZDM@28221|Deltaproteobacteria,2Z1WN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3901137_12	1254432.SCE1572_34545	0.0003535	52.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	pcm	-	2.1.1.77,2.7.7.7	ko:K00573,ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	Calx-beta,Gram_pos_anchor,Rib,YSIRK_signal
SHD3_k127_3901137_11	1254432.SCE1572_02315	2.747e-05	55.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_3901137_7	479434.Sthe_1133	6.748e-22	106.0	2DYB6@1|root,3490S@2|Bacteria	479434.Sthe_1133|-	S	Polysaccharide lyase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3910942_0	1122919.KB905581_gene3124	7.402e-243	794.0	COG2755@1|root,COG3401@1|root,COG5492@1|root,COG2755@2|Bacteria,COG3401@2|Bacteria,COG5492@2|Bacteria,1TQR3@1239|Firmicutes,4HBSX@91061|Bacilli,26QDW@186822|Paenibacillaceae	91061|Bacilli	M	cell wall organization	-	-	4.2.2.23	ko:K18197	-	-	-	-	ko00000,ko01000	-	PL11	-	Big_2,ChitinaseA_N,Lipase_GDSL_2,fn3
SHD3_k127_3910942_2	714943.Mucpa_1877	7.278e-14	85.0	COG1595@1|root,COG2374@1|root,COG3291@1|root,COG4733@1|root,COG1595@2|Bacteria,COG2374@2|Bacteria,COG3291@2|Bacteria,COG4733@2|Bacteria,4PHZI@976|Bacteroidetes,1IW7Q@117747|Sphingobacteriia	976|Bacteroidetes	K	SPTR Fibronectin type III domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_3,Glyco_hydro_cc,Laminin_G_3
SHD3_k127_3910942_1	1280390.CBQR020000058_gene1137	4.822e-26	124.0	COG3533@1|root,COG3533@2|Bacteria,1U157@1239|Firmicutes,4HT9T@91061|Bacilli,26UV2@186822|Paenibacillaceae	91061|Bacilli	G	Concanavalin A-like lectin/glucanases superfamily	M1-853	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SHD3_k127_3919077_9	448385.sce1052	2.781e-57	209.0	2BT1V@1|root,32N66@2|Bacteria,1QAJD@1224|Proteobacteria,43E1N@68525|delta/epsilon subdivisions,2WZFU@28221|Deltaproteobacteria,2Z21P@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3919077_4	1192034.CAP_3803	1.821e-102	363.0	COG1413@1|root,COG1413@2|Bacteria,1PYBK@1224|Proteobacteria,43E33@68525|delta/epsilon subdivisions,2WZJM@28221|Deltaproteobacteria,2Z29W@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_3919077_8	322710.Avin_20730	2.493e-61	224.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	COG0451 Nucleoside-diphosphate-sugar epimerases	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
SHD3_k127_3919077_10	448385.sce7200	7.81e-52	201.0	COG0308@1|root,COG0308@2|Bacteria,1NJK3@1224|Proteobacteria,42Y4Q@68525|delta/epsilon subdivisions,2WTET@28221|Deltaproteobacteria,2YVW2@29|Myxococcales	28221|Deltaproteobacteria	E	aminopeptidase N	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_MA_2
SHD3_k127_3919077_15	338963.Pcar_1323	8.34e-16	81.0	COG1605@1|root,COG1605@2|Bacteria,1Q1RX@1224|Proteobacteria,42U9H@68525|delta/epsilon subdivisions,2WQ7P@28221|Deltaproteobacteria,43SMW@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Chorismate mutase type II	-	-	5.4.99.5	ko:K04093	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2
SHD3_k127_3919077_6	1254432.SCE1572_42265	6.663e-66	241.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_3919077_5	1207063.P24_04694	3.43e-78	267.0	COG4122@1|root,COG4122@2|Bacteria,1RB34@1224|Proteobacteria,2VGIH@28211|Alphaproteobacteria,2JS0H@204441|Rhodospirillales	204441|Rhodospirillales	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
SHD3_k127_3919077_7	1313304.CALK_2538	5.866e-63	224.0	COG0118@1|root,COG0118@2|Bacteria	2|Bacteria	E	glutamine metabolic process	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
SHD3_k127_3919077_3	1313304.CALK_2539	1.589e-117	386.0	COG0107@1|root,COG0107@2|Bacteria	2|Bacteria	E	imidazoleglycerol-phosphate synthase activity	hisF	GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SHD3_k127_3919077_2	1123393.KB891316_gene2018	1.724e-134	435.0	28HGI@1|root,2Z7SC@2|Bacteria,1MWKC@1224|Proteobacteria,2VP5Q@28216|Betaproteobacteria	28216|Betaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3919077_12	204669.Acid345_4002	2.199e-46	180.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SHD3_k127_3919077_11	335541.Swol_1039	1.964e-46	177.0	COG2928@1|root,COG2928@2|Bacteria,1VBFF@1239|Firmicutes,25DJP@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF502
SHD3_k127_3919077_1	1254432.SCE1572_20060	6.799e-179	574.0	COG3604@1|root,COG3604@2|Bacteria,1QTT3@1224|Proteobacteria,42Y69@68525|delta/epsilon subdivisions,2X7TS@28221|Deltaproteobacteria,2YXZZ@29|Myxococcales	28221|Deltaproteobacteria	K	Domain present in phytochromes and cGMP-specific phosphodiesterases.	-	-	-	ko:K12266	ko05132,map05132	-	-	-	ko00000,ko00001,ko03000	-	-	-	GAF,HTH_8,Sigma54_activat
SHD3_k127_3919077_0	1254432.SCE1572_20065	0.0	1045.0	COG3256@1|root,COG3256@2|Bacteria,1MVT1@1224|Proteobacteria,42NBM@68525|delta/epsilon subdivisions,2WKTG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	PFAM Cytochrome c oxidase, subunit I	-	-	1.7.2.5	ko:K04561	ko00910,ko01120,map00910,map01120	M00529	R00294	RC02794	ko00000,ko00001,ko00002,ko01000	3.D.4.10	-	-	COX1
SHD3_k127_3919077_13	404589.Anae109_2428	3.264e-27	117.0	COG3945@1|root,COG3945@2|Bacteria,1NG3G@1224|Proteobacteria,42WHU@68525|delta/epsilon subdivisions,2WRK5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SHD3_k127_3919077_14	1192034.CAP_8111	4.42e-18	94.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_8111|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3919077_16	448385.sce6866	3.266e-11	66.0	COG5592@1|root,COG5592@2|Bacteria	2|Bacteria	I	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Phasin_2
SHD3_k127_3919550_15	378806.STAUR_5256	9.254e-24	103.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RGDF@1224|Proteobacteria,42NRI@68525|delta/epsilon subdivisions,2X78P@28221|Deltaproteobacteria,2YXRC@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_3919550_10	1192034.CAP_8013	2.716e-69	247.0	COG0438@1|root,COG0438@2|Bacteria,1PY46@1224|Proteobacteria,4352X@68525|delta/epsilon subdivisions,2X94R@28221|Deltaproteobacteria,2Z1XM@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
SHD3_k127_3919550_13	1254432.SCE1572_10925	5.466e-29	117.0	COG0828@1|root,COG0828@2|Bacteria,1PDBN@1224|Proteobacteria,435FI@68525|delta/epsilon subdivisions,2WZT4@28221|Deltaproteobacteria,2Z2PN@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
SHD3_k127_3919550_3	1267535.KB906767_gene5316	1.146e-210	693.0	COG0553@1|root,COG0553@2|Bacteria,3Y7CF@57723|Acidobacteria	57723|Acidobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
SHD3_k127_3919550_12	631362.Thi970DRAFT_01668	6.783e-61	224.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pyrroloquinoline quinone biosynthesis protein E	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SHD3_k127_3919550_11	631362.Thi970DRAFT_01668	2.482e-63	231.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pyrroloquinoline quinone biosynthesis protein E	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SHD3_k127_3919550_9	1297742.A176_00270	4.85e-81	287.0	COG2823@1|root,COG5637@1|root,COG2823@2|Bacteria,COG5637@2|Bacteria,1RI3F@1224|Proteobacteria,437A8@68525|delta/epsilon subdivisions,2X2EK@28221|Deltaproteobacteria,2YVIY@29|Myxococcales	28221|Deltaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
SHD3_k127_3919550_16	1254432.SCE1572_25350	6.931e-21	102.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_25350|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3919550_1	448385.sce0609	9.778e-296	978.0	COG0457@1|root,COG0457@2|Bacteria,1PXR4@1224|Proteobacteria,43DWZ@68525|delta/epsilon subdivisions,2WZ3E@28221|Deltaproteobacteria,2Z18R@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3919550_0	448385.sce0608	0.0	1206.0	COG0457@1|root,COG0457@2|Bacteria,1QA96@1224|Proteobacteria,43DYT@68525|delta/epsilon subdivisions,2X92B@28221|Deltaproteobacteria,2Z1IW@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3919550_4	1192034.CAP_5028	7.414e-201	675.0	COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42NZK@68525|delta/epsilon subdivisions,2WIY5@28221|Deltaproteobacteria,2YVS5@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_14,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8,zinc_ribbon_4
SHD3_k127_3919550_8	1173028.ANKO01000017_gene292	3.724e-81	286.0	COG2227@1|root,COG2227@2|Bacteria,1G0ZD@1117|Cyanobacteria,1H8ZA@1150|Oscillatoriales	1117|Cyanobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_3919550_2	452637.Oter_4352	3.934e-238	745.0	COG4868@1|root,COG4868@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF1846)	XK27_07020	-	-	-	-	-	-	-	-	-	-	-	DUF1846
SHD3_k127_3919550_7	886293.Sinac_4681	3.389e-83	295.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	Abi,Exosortase_EpsH
SHD3_k127_3919550_5	196162.Noca_1954	3.71e-166	535.0	COG1858@1|root,COG1858@2|Bacteria	2|Bacteria	C	electron transfer activity	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,DHOR
SHD3_k127_3919550_6	1192034.CAP_8124	8.03e-85	297.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SHD3_k127_3928463_5	316067.Geob_0965	1.097e-35	139.0	COG0277@1|root,COG0277@2|Bacteria	2|Bacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
SHD3_k127_3928463_1	316067.Geob_0964	8.015e-122	408.0	COG3320@1|root,COG3320@2|Bacteria,1QSHC@1224|Proteobacteria,42W94@68525|delta/epsilon subdivisions,2WR9E@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
SHD3_k127_3928463_3	861299.J421_0350	4.035e-102	353.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	pglA	-	3.2.1.15	ko:K01184	ko00040,ko01100,map00040,map01100	M00081	R01982,R02360	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_28,Pectate_lyase_3,Pectinesterase
SHD3_k127_3928463_6	935845.JADQ01000032_gene1303	1.135e-20	104.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli,26TP1@186822|Paenibacillaceae	91061|Bacilli	S	Oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SHD3_k127_3928463_7	1416759.AYMR01000007_gene909	2.301e-15	89.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF4214,F5_F8_type_C
SHD3_k127_3928463_4	1242864.D187_008587	1.006e-47	186.0	COG0006@1|root,COG4284@1|root,COG0006@2|Bacteria,COG4284@2|Bacteria,1NQW9@1224|Proteobacteria,42YFV@68525|delta/epsilon subdivisions,2WTVE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M24
SHD3_k127_3928463_0	448385.sce8336	1.475e-216	706.0	COG0616@1|root,COG0616@2|Bacteria,1MUXE@1224|Proteobacteria,42QUN@68525|delta/epsilon subdivisions,2WN6Q@28221|Deltaproteobacteria,2YU60@29|Myxococcales	28221|Deltaproteobacteria	OU	signal peptide peptidase SppA, 36K type	sppA2	-	-	ko:K04773	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
SHD3_k127_3928463_8	1463857.JOFZ01000001_gene5562	1.023e-05	57.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_3928463_2	1254432.SCE1572_48560	4.754e-104	350.0	COG0263@1|root,COG0263@2|Bacteria,1MUBG@1224|Proteobacteria,42NEA@68525|delta/epsilon subdivisions,2WIVS@28221|Deltaproteobacteria,2YTY2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_3198	AA_kinase,PUA
SHD3_k127_3935245_6	1125863.JAFN01000001_gene1549	1.74e-08	56.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
SHD3_k127_3935245_2	663610.JQKO01000001_gene626	4.833e-34	134.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,3NBSY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SHD3_k127_3935245_0	448385.sce2258	1.503e-64	230.0	28PB0@1|root,2ZC40@2|Bacteria,1Q1BW@1224|Proteobacteria,4376A@68525|delta/epsilon subdivisions,2X3U5@28221|Deltaproteobacteria,2YX4A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3935245_4	448385.sce7744	9.704e-14	82.0	COG3266@1|root,COG3266@2|Bacteria,1QA9E@1224|Proteobacteria,434X4@68525|delta/epsilon subdivisions,2WZ81@28221|Deltaproteobacteria,2Z1J2@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3935245_3	391625.PPSIR1_29153	1.787e-27	119.0	COG1595@1|root,COG1595@2|Bacteria,1QR72@1224|Proteobacteria,43E0Y@68525|delta/epsilon subdivisions,2WZDM@28221|Deltaproteobacteria,2Z1WN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_3935245_5	448385.sce1339	5.401e-12	76.0	2AJJV@1|root,31A6Q@2|Bacteria,1Q51M@1224|Proteobacteria,435IH@68525|delta/epsilon subdivisions,2WZW5@28221|Deltaproteobacteria,2Z2VC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3935245_1	1121430.JMLG01000002_gene1059	9.772e-64	233.0	COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia,263EX@186807|Peptococcaceae	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_3941787_1	1172180.KB911807_gene6567	1.634e-68	257.0	COG4225@1|root,COG4225@2|Bacteria,2I8PZ@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl Hydrolase Family 88	-	-	3.2.1.172	ko:K15532	-	-	-	-	ko00000,ko01000	-	GH105	-	CBM_6,Glyco_hydro_88
SHD3_k127_3941787_2	219305.MCAG_00228	7.249e-51	193.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4DI53@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 12 (cellulase H) family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12
SHD3_k127_3941787_0	234267.Acid_0588	3.441e-135	453.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat
SHD3_k127_3941787_4	857087.Metme_1275	1.975e-05	55.0	COG1842@1|root,COG1842@2|Bacteria,1N09Q@1224|Proteobacteria,1S8S2@1236|Gammaproteobacteria,1XFIG@135618|Methylococcales	135618|Methylococcales	KT	PFAM PspA IM30	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SHD3_k127_3941787_3	1283300.ATXB01000002_gene2627	1.749e-09	66.0	293XF@1|root,2ZRCI@2|Bacteria,1RGQW@1224|Proteobacteria,1S41W@1236|Gammaproteobacteria,1XDZ3@135618|Methylococcales	135618|Methylococcales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3948933_1	1192034.CAP_5418	4.597e-17	91.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_5418|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3948933_2	555779.Dthio_PD1970	3.661e-12	80.0	COG0457@1|root,COG1032@1|root,COG0457@2|Bacteria,COG1032@2|Bacteria,1MWR0@1224|Proteobacteria,42PFW@68525|delta/epsilon subdivisions,2WJ1N@28221|Deltaproteobacteria,2MANW@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM,TPR_1
SHD3_k127_3948933_0	1192034.CAP_2703	2.419e-212	672.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WTUX@28221|Deltaproteobacteria,2YTTM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SHD3_k127_39531_11	929713.NIASO_03420	6.581e-08	65.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Cytochrom_C,Lectin_legB,Lumazine_bd_2
SHD3_k127_39531_8	298654.FraEuI1c_3358	7.859e-19	100.0	COG1520@1|root,COG1520@2|Bacteria,2GR6Q@201174|Actinobacteria	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Tachylectin
SHD3_k127_39531_7	324602.Caur_3908	5.913e-23	104.0	COG0110@1|root,COG0110@2|Bacteria,2G7B9@200795|Chloroflexi	200795|Chloroflexi	S	PFAM transferase hexapeptide repeat containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
SHD3_k127_39531_5	1254432.SCE1572_38940	2.215e-32	139.0	2AN96@1|root,31D78@2|Bacteria,1QAAX@1224|Proteobacteria,434Y2@68525|delta/epsilon subdivisions,2WZ8X@28221|Deltaproteobacteria,2Z1KT@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SHD3_k127_39531_0	234267.Acid_0658	2.608e-244	772.0	COG0451@1|root,COG0463@1|root,COG0451@2|Bacteria,COG0463@2|Bacteria,3Y8F6@57723|Acidobacteria	57723|Acidobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Epimerase
SHD3_k127_39531_10	926559.JoomaDRAFT_0718	5.019e-08	63.0	COG2353@1|root,COG2353@2|Bacteria	2|Bacteria	O	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
SHD3_k127_39531_2	1242864.D187_008088	8.616e-73	260.0	29EP2@1|root,301KY@2|Bacteria,1Q96E@1224|Proteobacteria,437IB@68525|delta/epsilon subdivisions,2X2RW@28221|Deltaproteobacteria,2Z2TH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_39531_4	448385.sce7865	2.893e-37	145.0	COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,42U37@68525|delta/epsilon subdivisions,2WQ9M@28221|Deltaproteobacteria,2Z1YM@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SHD3_k127_39531_1	1123371.ATXH01000010_gene723	2.72e-217	683.0	COG0174@1|root,COG0174@2|Bacteria,2GH5N@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	E	Glutamine synthetase, catalytic domain	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
SHD3_k127_39531_3	1192034.CAP_2847	1.263e-53	195.0	COG0347@1|root,COG0347@2|Bacteria,1RGWK@1224|Proteobacteria,42SJJ@68525|delta/epsilon subdivisions,2WP4E@28221|Deltaproteobacteria,2YVH0@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the P(II) protein family	glnB	-	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
SHD3_k127_39531_6	439235.Dalk_2543	1.517e-30	130.0	COG2515@1|root,COG2515@2|Bacteria,1MVYF@1224|Proteobacteria,42PWI@68525|delta/epsilon subdivisions,2WKFE@28221|Deltaproteobacteria,2MKKB@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.4.1.15	ko:K05396	ko00270,map00270	-	R01874	RC00382	ko00000,ko00001,ko01000	-	-	-	PALP
SHD3_k127_395556_2	391603.FBALC1_14557	1.558e-05	57.0	COG4676@1|root,COG4676@2|Bacteria,4NISW@976|Bacteroidetes,1I0BF@117743|Flavobacteriia	976|Bacteroidetes	O	Peptidyl-prolyl cis-trans isomerase	-	-	-	-	-	-	-	-	-	-	-	-	UPF0560
SHD3_k127_395556_0	290397.Adeh_0078	3.567e-29	126.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_395556_1	1121918.ARWE01000001_gene2765	1.139e-07	62.0	COG0457@1|root,COG0745@1|root,COG0457@2|Bacteria,COG0745@2|Bacteria	1121918.ARWE01000001_gene2765|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3963723_5	626523.GCWU000342_00301	0.0002372	48.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
SHD3_k127_3963723_0	1283300.ATXB01000002_gene2668	1.603e-181	589.0	COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,1XE3D@135618|Methylococcales	1236|Gammaproteobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	-	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
SHD3_k127_3963723_1	1254432.SCE1572_18490	1.872e-93	323.0	COG3386@1|root,COG3386@2|Bacteria,1QY38@1224|Proteobacteria,43CUW@68525|delta/epsilon subdivisions,2X82P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	-	-	-	-	-	-	-	-	-	-	SGL
SHD3_k127_3963723_4	1196323.ALKF01000150_gene1342	6.912e-09	59.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,26RR1@186822|Paenibacillaceae	91061|Bacilli	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SHD3_k127_3963723_6	235909.GK1257	0.000248	52.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli,1WERC@129337|Geobacillus	91061|Bacilli	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SHD3_k127_3963723_3	443144.GM21_1334	5.993e-18	87.0	COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,42ME5@68525|delta/epsilon subdivisions,2WKA2@28221|Deltaproteobacteria,43TSA@69541|Desulfuromonadales	28221|Deltaproteobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
SHD3_k127_3975939_8	1128421.JAGA01000003_gene3679	1.462e-39	153.0	COG5297@1|root,COG5297@2|Bacteria,2NQDB@2323|unclassified Bacteria	2|Bacteria	G	CBD_II	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_3,Dockerin_1,Glyco_hydro_9,fn3
SHD3_k127_3975939_2	1128421.JAGA01000003_gene3679	1.109e-239	751.0	COG5297@1|root,COG5297@2|Bacteria,2NQDB@2323|unclassified Bacteria	2|Bacteria	G	CBD_II	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_3,Dockerin_1,Glyco_hydro_9,fn3
SHD3_k127_3975939_1	985665.HPL003_22375	0.0	1238.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,4HFBX@91061|Bacilli,26RCV@186822|Paenibacillaceae	91061|Bacilli	G	Cellobiose phosphorylase	chvB3	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36,Glycoamylase
SHD3_k127_3975939_3	1121381.JNIV01000176_gene1275	5.022e-99	340.0	COG2199@1|root,COG3706@2|Bacteria,1WIYY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	T	TIGRFAM diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
SHD3_k127_3975939_7	546414.Deide_11970	3.409e-50	204.0	COG2202@1|root,COG3852@1|root,COG2202@2|Bacteria,COG3852@2|Bacteria	2|Bacteria	T	phosphorelay sensor kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg,cNMP_binding
SHD3_k127_3975939_4	1499967.BAYZ01000108_gene2206	1.837e-94	341.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
SHD3_k127_3975939_5	1192034.CAP_0103	2.633e-79	290.0	2AH4I@1|root,317E5@2|Bacteria,1PYQB@1224|Proteobacteria,435HF@68525|delta/epsilon subdivisions,2X99V@28221|Deltaproteobacteria,2Z2T7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3975939_6	1254432.SCE1572_20805	3.604e-55	201.0	COG0204@1|root,COG0204@2|Bacteria,1MY51@1224|Proteobacteria,42S1J@68525|delta/epsilon subdivisions,2WP2S@28221|Deltaproteobacteria,2YVUS@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SHD3_k127_3975939_0	448385.sce6592	0.0	1269.0	COG0457@1|root,COG0457@2|Bacteria,1PC8F@1224|Proteobacteria,438AR@68525|delta/epsilon subdivisions,2X3K3@28221|Deltaproteobacteria,2YWDI@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_19
SHD3_k127_3977950_1	1397528.Q671_12880	6.241e-14	84.0	COG2801@1|root,COG2801@2|Bacteria,1MVC8@1224|Proteobacteria,1RXYF@1236|Gammaproteobacteria,1XHWD@135619|Oceanospirillales	135619|Oceanospirillales	L	HTH-like domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
SHD3_k127_3977950_0	768710.DesyoDRAFT_4194	1.924e-29	136.0	COG3209@1|root,COG3209@2|Bacteria,1UZR4@1239|Firmicutes,24CNR@186801|Clostridia	186801|Clostridia	M	virulence plasmid 65kDa B protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
SHD3_k127_3989373_4	1034943.BN1094_00763	2.897e-22	108.0	COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,1SBJ9@1236|Gammaproteobacteria,1JCX8@118969|Legionellales	118969|Legionellales	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	cypB	-	5.2.1.8	ko:K03767	ko01503,ko04217,map01503,map04217	-	-	-	ko00000,ko00001,ko01000,ko03110,ko04147	-	-	-	Pro_isomerase
SHD3_k127_3989373_1	448385.sce4949	4.688e-212	693.0	COG0402@1|root,COG1506@1|root,COG5184@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_3989373_5	1254432.SCE1572_16065	5.157e-10	63.0	COG2931@1|root,COG2931@2|Bacteria,1R2A3@1224|Proteobacteria	1224|Proteobacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3989373_2	1254432.SCE1572_28135	1.402e-186	593.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria,437EK@68525|delta/epsilon subdivisions,2XA2I@28221|Deltaproteobacteria,2Z0XV@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase_phd
SHD3_k127_3989373_0	234267.Acid_1388	2.91e-293	922.0	COG0457@1|root,COG0823@1|root,COG0457@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	dppX	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
SHD3_k127_3989373_3	33178.CADATEAP00010399	4.92e-57	212.0	COG3509@1|root,2QU71@2759|Eukaryota,39T0C@33154|Opisthokonta,3NYZ8@4751|Fungi,3QPJY@4890|Ascomycota,20K5U@147545|Eurotiomycetes,3SC58@5042|Eurotiales	4751|Fungi	O	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	CBM_1,Esterase,Peptidase_S9
SHD3_k127_398945_3	1121272.KB903251_gene868	4.202e-19	96.0	COG1413@1|root,COG1413@2|Bacteria,2GKP6@201174|Actinobacteria,4DC90@85008|Micromonosporales	201174|Actinobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_398945_4	1123277.KB893200_gene6379	5.263e-15	89.0	COG4447@1|root,COG4447@2|Bacteria	2|Bacteria	S	cellulose binding	-	GO:0003674,GO:0005488,GO:0005515,GO:0042802	3.2.1.4,3.2.1.78	ko:K01179,ko:K01218	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R01332,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000	-	GH26,GH5,GH9	-	CBM_3,CBM_35,CBM_X2,Cu-binding_MopE,Dockerin_1,Glyco_hydro_26,Glyco_hydro_48,Glyco_hydro_9
SHD3_k127_398945_1	1340493.JNIF01000003_gene2360	1.135e-57	212.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	coxC	GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007	-	ko:K02477,ko:K07705,ko:K21696	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022,ko03000	-	-	-	LytTR,MHYT,Response_reg
SHD3_k127_398945_0	234267.Acid_2310	2.513e-58	216.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
SHD3_k127_398945_2	1267535.KB906767_gene1907	1.606e-22	97.0	COG0693@1|root,COG0693@2|Bacteria,3Y5M0@57723|Acidobacteria	57723|Acidobacteria	S	DJ-1/PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
SHD3_k127_3999601_1	1242864.D187_005157	1.009e-05	55.0	COG0642@1|root,COG2205@2|Bacteria	1242864.D187_005157|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_3999601_0	1242864.D187_005156	1.516e-239	760.0	COG0467@1|root,COG0467@2|Bacteria,1NM7E@1224|Proteobacteria,42SM2@68525|delta/epsilon subdivisions,2WPEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SHD3_k127_4008314_2	448385.sce4279	9.98e-37	156.0	2C4HX@1|root,2Z9XP@2|Bacteria,1MY22@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4008314_3	1242864.D187_006914	6.295e-28	117.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	4.4.1.5	ko:K01759,ko:K08234	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
SHD3_k127_4008314_1	935863.AWZR01000007_gene141	5.875e-59	218.0	COG2227@1|root,COG2227@2|Bacteria,1PGKN@1224|Proteobacteria,1TKBG@1236|Gammaproteobacteria,1XBAH@135614|Xanthomonadales	135614|Xanthomonadales	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SHD3_k127_4008314_0	378806.STAUR_2012	1.763e-102	344.0	2DB7V@1|root,2Z7NX@2|Bacteria,1N9SI@1224|Proteobacteria,43ANT@68525|delta/epsilon subdivisions,2WTAF@28221|Deltaproteobacteria,2YYSS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4019283_1	1192034.CAP_8370	2.41e-159	519.0	COG4775@1|root,COG4775@2|Bacteria,1PBXZ@1224|Proteobacteria,433TZ@68525|delta/epsilon subdivisions,2X3G3@28221|Deltaproteobacteria,2YVY6@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag,POTRA
SHD3_k127_4019283_3	1192034.CAP_8371	4.377e-36	149.0	2ANWS@1|root,31DXD@2|Bacteria,1QB7T@1224|Proteobacteria,43E5G@68525|delta/epsilon subdivisions,2X98S@28221|Deltaproteobacteria,2Z2NC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4019283_0	1192034.CAP_7320	2.2e-266	837.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_7320|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_402245_4	1254432.SCE1572_52180	1.148e-74	256.0	COG0231@1|root,COG0231@2|Bacteria,1MW2J@1224|Proteobacteria,42N6H@68525|delta/epsilon subdivisions,2WNG7@28221|Deltaproteobacteria,2YUWK@29|Myxococcales	28221|Deltaproteobacteria	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
SHD3_k127_402245_3	1254432.SCE1572_52175	2.333e-85	293.0	COG1729@1|root,COG1729@2|Bacteria,1QXUN@1224|Proteobacteria,43C75@68525|delta/epsilon subdivisions,2X7HE@28221|Deltaproteobacteria,2YXEZ@29|Myxococcales	28221|Deltaproteobacteria	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_6
SHD3_k127_402245_2	570952.ATVH01000018_gene3217	3.169e-89	303.0	COG0351@1|root,COG0351@2|Bacteria,1MU9J@1224|Proteobacteria,2TUKR@28211|Alphaproteobacteria,2JPMV@204441|Rhodospirillales	204441|Rhodospirillales	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
SHD3_k127_402245_0	1303518.CCALI_00158	7.556e-260	815.0	COG0166@1|root,COG0166@2|Bacteria	2|Bacteria	G	Belongs to the GPI family	pgi	GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iEcSMS35_1347.EcSMS35_4486	PGI
SHD3_k127_402245_1	1125863.JAFN01000001_gene3117	1.004e-216	693.0	COG0058@1|root,COG0058@2|Bacteria,1MW4J@1224|Proteobacteria,42MEQ@68525|delta/epsilon subdivisions,2WIPF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM glycosyl transferase, family 35	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
SHD3_k127_402245_5	941449.dsx2_0194	8.251e-47	179.0	COG1418@1|root,COG1418@2|Bacteria,1RB2W@1224|Proteobacteria,42UMT@68525|delta/epsilon subdivisions,2WQD6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
SHD3_k127_402245_8	1192034.CAP_1507	3.073e-14	81.0	2DGCA@1|root,2ZVDU@2|Bacteria,1PCAI@1224|Proteobacteria,43E4G@68525|delta/epsilon subdivisions,2WZPI@28221|Deltaproteobacteria,2Z2H4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_402245_7	1536769.P40081_27865	4.977e-20	94.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,4HCT0@91061|Bacilli,27496@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
SHD3_k127_4022469_1	765911.Thivi_0047	5.706e-106	360.0	COG2843@1|root,COG2843@2|Bacteria,1PGVS@1224|Proteobacteria,1RXHX@1236|Gammaproteobacteria,1X1CU@135613|Chromatiales	135613|Chromatiales	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
SHD3_k127_4022469_8	159087.Daro_1193	4.712e-15	79.0	2E2Z5@1|root,32VPF@2|Bacteria,1N0U4@1224|Proteobacteria,2VUC1@28216|Betaproteobacteria,2KZ2Z@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4022469_6	1123487.KB892866_gene1656	8.756e-33	134.0	COG4319@1|root,COG4319@2|Bacteria,1N8K3@1224|Proteobacteria,2W5GJ@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Calcium/calmodulin dependent protein kinase II association domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4022469_2	530564.Psta_4074	1.146e-82	284.0	COG1595@1|root,COG1595@2|Bacteria,2IYFG@203682|Planctomycetes	203682|Planctomycetes	K	COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
SHD3_k127_4022469_5	448385.sce8901	1.874e-33	136.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_4022469_4	448385.sce8660	7.565e-40	157.0	COG0789@1|root,COG0789@2|Bacteria,1MWN0@1224|Proteobacteria,43EX6@68525|delta/epsilon subdivisions,2X2FH@28221|Deltaproteobacteria,2YYBB@29|Myxococcales	28221|Deltaproteobacteria	K	TipAS antibiotic-recognition domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
SHD3_k127_4022469_7	1297742.A176_05026	4.377e-30	125.0	COG3795@1|root,COG3795@2|Bacteria	2|Bacteria	F	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
SHD3_k127_4022469_0	886293.Sinac_0949	1.054e-248	802.0	COG3250@1|root,COG3250@2|Bacteria,2IWTW@203682|Planctomycetes	203682|Planctomycetes	G	Glycosyl hydrolases family 2	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Glyco_hydro_43
SHD3_k127_4022469_3	1167006.UWK_03371	4.513e-42	162.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,42PFX@68525|delta/epsilon subdivisions,2WJS3@28221|Deltaproteobacteria,2MHR3@213118|Desulfobacterales	28221|Deltaproteobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
SHD3_k127_4026932_14	977880.RALTA_B0625	2.361e-26	111.0	COG0477@1|root,COG0477@2|Bacteria,1NS3F@1224|Proteobacteria,2WGGT@28216|Betaproteobacteria,1KIE5@119060|Burkholderiaceae	28216|Betaproteobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
SHD3_k127_4026932_16	1297742.A176_04856	2.368e-11	72.0	COG5612@1|root,COG5612@2|Bacteria,1PBU8@1224|Proteobacteria,433TF@68525|delta/epsilon subdivisions,2X3E2@28221|Deltaproteobacteria,2YVN2@29|Myxococcales	28221|Deltaproteobacteria	S	Heavy-metal resistance	-	-	-	-	-	-	-	-	-	-	-	-	Metal_resist
SHD3_k127_4026932_1	748658.KB907314_gene31	9.829e-270	856.0	COG3280@1|root,COG3280@2|Bacteria	2|Bacteria	G	synthase	treY	GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576	2.4.1.25,5.4.99.15	ko:K00705,ko:K06044	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R01824,R05196,R09995	RC00049	ko00000,ko00001,ko00002,ko01000	-	GH13,GH77	-	Alpha-amylase,Glyco_hydro_77
SHD3_k127_4026932_2	1279019.ARQK01000061_gene1757	3.607e-226	719.0	COG0296@1|root,COG0296@2|Bacteria,1MVM7@1224|Proteobacteria,1RP2N@1236|Gammaproteobacteria,1WWIM@135613|Chromatiales	135613|Chromatiales	G	TIGRFAM malto-oligosyltrehalose trehalohydrolase	-	-	3.2.1.141	ko:K01236	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11256	RC00049	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48,DUF3459
SHD3_k127_4026932_3	448385.sce4549	2.843e-165	546.0	COG0457@1|root,COG0457@2|Bacteria,1QX7S@1224|Proteobacteria,43C0S@68525|delta/epsilon subdivisions,2X7BD@28221|Deltaproteobacteria,2YV1Y@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4026932_0	448385.sce2838	0.0	1040.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SHD3_k127_4026932_12	1192034.CAP_4347	1.322e-56	207.0	2A6Q2@1|root,30VI0@2|Bacteria,1QABI@1224|Proteobacteria,434YG@68525|delta/epsilon subdivisions,2X92X@28221|Deltaproteobacteria,2Z1MS@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4026932_6	1254432.SCE1572_17360	8.769e-81	279.0	COG0131@1|root,COG0131@2|Bacteria,1MWBS@1224|Proteobacteria,42NIV@68525|delta/epsilon subdivisions,2WNA4@28221|Deltaproteobacteria,2YV6W@29|Myxococcales	28221|Deltaproteobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
SHD3_k127_4026932_8	1254432.SCE1572_17275	7.812e-79	270.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,42NRX@68525|delta/epsilon subdivisions,2WK1K@28221|Deltaproteobacteria,2YVBU@29|Myxococcales	28221|Deltaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0388	His_biosynth
SHD3_k127_4026932_5	448385.sce2812	6.257e-82	291.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce2812|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4026932_7	1192034.CAP_4352	2.953e-80	274.0	COG0558@1|root,COG0558@2|Bacteria,1RCZ7@1224|Proteobacteria,42QQ4@68525|delta/epsilon subdivisions,2WQGH@28221|Deltaproteobacteria,2YVBE@29|Myxococcales	28221|Deltaproteobacteria	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	pgsA	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
SHD3_k127_4026932_15	290397.Adeh_0702	6.114e-12	69.0	COG1987@1|root,COG1987@2|Bacteria,1N73W@1224|Proteobacteria,42VAB@68525|delta/epsilon subdivisions,2WR6X@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Flagellar biosynthetic protein FliQ	fliQ	-	-	ko:K02420,ko:K03227	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_3
SHD3_k127_4026932_4	1254432.SCE1572_17250	2.151e-85	298.0	COG2269@1|root,COG2269@2|Bacteria,1MU97@1224|Proteobacteria,42MAN@68525|delta/epsilon subdivisions,2WJBB@28221|Deltaproteobacteria,2YUT5@29|Myxococcales	28221|Deltaproteobacteria	J	tRNA synthetases class II (D, K and N)	genX	-	-	ko:K04568	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	tRNA-synt_2
SHD3_k127_4026932_11	448385.sce2983	2.024e-59	216.0	COG0503@1|root,COG0503@2|Bacteria,1MVZ6@1224|Proteobacteria,42QSH@68525|delta/epsilon subdivisions,2WP5X@28221|Deltaproteobacteria,2YY5P@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
SHD3_k127_4026932_10	448385.sce4838	9.286e-71	258.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
SHD3_k127_4026932_13	391625.PPSIR1_11130	1.001e-26	114.0	COG1262@1|root,COG1262@2|Bacteria,1QADB@1224|Proteobacteria,43503@68525|delta/epsilon subdivisions,2X93Q@28221|Deltaproteobacteria,2Z1R3@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_4039316_2	1254432.SCE1572_45375	1.273e-123	417.0	COG2304@1|root,COG3712@1|root,COG2304@2|Bacteria,COG3712@2|Bacteria,1QRQ1@1224|Proteobacteria,4341K@68525|delta/epsilon subdivisions,2X4NI@28221|Deltaproteobacteria,2YZAV@29|Myxococcales	28221|Deltaproteobacteria	PT	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,VIT,VWA_3
SHD3_k127_4039316_3	290397.Adeh_1157	6.655e-102	347.0	28HX6@1|root,2Z82X@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4039316_1	309798.COPRO5265_1482	2.712e-142	459.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia	186801|Clostridia	E	aspartate--ammonia ligase	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
SHD3_k127_4039316_4	1379698.RBG1_1C00001G0467	1.351e-80	279.0	COG0861@1|root,COG0861@2|Bacteria,2NNXY@2323|unclassified Bacteria	2|Bacteria	P	Integral membrane protein TerC family	terC	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
SHD3_k127_4039316_0	357808.RoseRS_1575	3.276e-154	503.0	COG1640@1|root,COG1640@2|Bacteria,2G668@200795|Chloroflexi,376Q1@32061|Chloroflexia	32061|Chloroflexia	G	PFAM glycoside hydrolase, family 77	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SHD3_k127_4039998_0	1192034.CAP_5866	6.595e-75	259.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_4039998_1	1168065.DOK_09601	1.608e-71	260.0	COG1373@1|root,COG1373@2|Bacteria,1MWBT@1224|Proteobacteria,1RPXG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
SHD3_k127_4039998_2	1254432.SCE1572_25680	2.393e-70	244.0	COG4636@1|root,COG4636@2|Bacteria,1Q8YX@1224|Proteobacteria,4344R@68525|delta/epsilon subdivisions,2X57Z@28221|Deltaproteobacteria,2Z08R@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_4045588_3	404589.Anae109_1597	1.896e-41	158.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SHD3_k127_4045588_0	448385.sce0929	6.56e-128	437.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,430V0@68525|delta/epsilon subdivisions,2WVT6@28221|Deltaproteobacteria,2YXP7@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9
SHD3_k127_4045588_4	1380391.JIAS01000015_gene78	7.616e-38	149.0	COG2208@1|root,COG2208@2|Bacteria,1N9UZ@1224|Proteobacteria,2U953@28211|Alphaproteobacteria,2JUWV@204441|Rhodospirillales	204441|Rhodospirillales	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
SHD3_k127_4045588_2	469383.Cwoe_3439	9.675e-43	160.0	COG2172@1|root,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
SHD3_k127_4045588_5	1206720.BAFQ01000108_gene2662	1.48e-35	143.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria,4G0GD@85025|Nocardiaceae	201174|Actinobacteria	T	STAS domain	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
SHD3_k127_4045588_1	1385518.N798_11920	3.51e-92	311.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria,4FG7K@85021|Intrasporangiaceae	201174|Actinobacteria	T	STAS domain	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
SHD3_k127_4074947_7	118161.KB235922_gene3131	2.203e-27	119.0	COG2442@1|root,COG2442@2|Bacteria,1G87F@1117|Cyanobacteria	1117|Cyanobacteria	S	COGs COG2442 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SHD3_k127_4074947_6	1254432.SCE1572_48940	2.11e-40	154.0	COG4634@1|root,COG4634@2|Bacteria,1RH7A@1224|Proteobacteria,42U78@68525|delta/epsilon subdivisions,2WQJY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4074947_9	1121448.DGI_1291	5.245e-13	71.0	COG1598@1|root,COG1598@2|Bacteria,1NMQ9@1224|Proteobacteria,43EUT@68525|delta/epsilon subdivisions,2X9PN@28221|Deltaproteobacteria,2MFP1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM Uncharacterised protein family UPF0150	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4074947_8	290317.Cpha266_1441	1.888e-23	100.0	COG1724@1|root,COG1724@2|Bacteria	2|Bacteria	N	mRNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
SHD3_k127_4074947_11	877421.AUJT01000002_gene1026	8.232e-09	58.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,27IM5@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SHD3_k127_4074947_0	448385.sce0425	1.307e-170	546.0	COG4198@1|root,COG4198@2|Bacteria,1NPPY@1224|Proteobacteria,42PTC@68525|delta/epsilon subdivisions,2WM3S@28221|Deltaproteobacteria,2YTUU@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
SHD3_k127_4074947_1	1192034.CAP_3414	2.997e-141	455.0	COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,42NCX@68525|delta/epsilon subdivisions,2WJUZ@28221|Deltaproteobacteria,2YXCF@29|Myxococcales	28221|Deltaproteobacteria	S	MCM2/3/5 family	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
SHD3_k127_4074947_2	448385.sce4440	3.835e-101	353.0	2AGZQ@1|root,3178G@2|Bacteria,1PYI9@1224|Proteobacteria,435DD@68525|delta/epsilon subdivisions,2WZQZ@28221|Deltaproteobacteria,2Z2JG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4074947_3	448385.sce3127	3.786e-93	327.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4084249_3	742733.HMPREF9469_04310	1.301e-35	141.0	COG0241@1|root,COG0241@2|Bacteria,1V6XD@1239|Firmicutes,24IZ4@186801|Clostridia,21Z1E@1506553|Lachnoclostridium	186801|Clostridia	E	Polynucleotide kinase 3 phosphatase	gmhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_6,Hydrolase_like,PNK3P
SHD3_k127_4084249_2	749222.Nitsa_1425	1.656e-60	216.0	COG0279@1|root,COG0279@2|Bacteria,1NVIE@1224|Proteobacteria,42QUT@68525|delta/epsilon subdivisions,2YNVS@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	G	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SHD3_k127_4084249_0	760142.Hipma_0110	1.465e-101	346.0	COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,42MC1@68525|delta/epsilon subdivisions,2WJ24@28221|Deltaproteobacteria,2M711@213113|Desulfurellales	28221|Deltaproteobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	hldD	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
SHD3_k127_4084249_1	525898.Sdel_1813	7.788e-96	323.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,1MV3Z@1224|Proteobacteria,42MBC@68525|delta/epsilon subdivisions,2YMZG@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	F	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose	hldE	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
SHD3_k127_4087236_0	404589.Anae109_2999	0.0	1202.0	COG0247@1|root,COG0277@1|root,COG0247@2|Bacteria,COG0277@2|Bacteria,1MU43@1224|Proteobacteria,42MZC@68525|delta/epsilon subdivisions,2WKRK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	CCG,DUF3683,FAD-oxidase_C,FAD_binding_4,Fer4_10,Fer4_8
SHD3_k127_4087236_1	1254432.SCE1572_09680	7.234e-150	494.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X7DF@28221|Deltaproteobacteria,2YY2W@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_4087236_2	335543.Sfum_2574	1.446e-97	329.0	COG0053@1|root,COG0053@2|Bacteria,1MUDS@1224|Proteobacteria,42NCJ@68525|delta/epsilon subdivisions,2WM7Z@28221|Deltaproteobacteria,2MQJH@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	ko:K13283	-	-	-	-	ko00000,ko02000	2.A.4.7.1	-	-	Cation_efflux,ZT_dimer
SHD3_k127_4087236_3	246197.MXAN_6933	1.927e-67	242.0	COG4636@1|root,COG4636@2|Bacteria,1PDM3@1224|Proteobacteria,43996@68525|delta/epsilon subdivisions,2X4GI@28221|Deltaproteobacteria,2YYZ8@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_4104115_9	1254432.SCE1572_14925	2.399e-21	99.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4104115_2	671143.DAMO_0932	1.284e-135	443.0	COG0463@1|root,COG0463@2|Bacteria,2NQWR@2323|unclassified Bacteria	2|Bacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Epimerase,GDP_Man_Dehyd,Glycos_transf_2
SHD3_k127_4104115_7	671143.DAMO_0931	6.036e-73	257.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	ubiE5	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
SHD3_k127_4104115_0	671143.DAMO_0933	1.098e-148	476.0	COG0451@1|root,COG0451@2|Bacteria,2NQSZ@2323|unclassified Bacteria	2|Bacteria	GM	NAD(P)H-binding	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SHD3_k127_4104115_3	1116472.MGMO_94c00220	1.733e-131	427.0	COG0673@1|root,COG0673@2|Bacteria,1MZIG@1224|Proteobacteria,1RS5T@1236|Gammaproteobacteria,1XEQF@135618|Methylococcales	135618|Methylococcales	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
SHD3_k127_4104115_1	1408164.MOLA814_00706	1.162e-143	465.0	COG2605@1|root,COG2605@2|Bacteria,1PKV9@1224|Proteobacteria,2VKPX@28216|Betaproteobacteria	28216|Betaproteobacteria	S	GHMP kinases N terminal domain	-	-	2.7.1.168	ko:K07031	ko00540,map00540	-	R09770	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
SHD3_k127_4104115_6	1408164.MOLA814_00704	1.789e-95	316.0	COG0279@1|root,COG0279@2|Bacteria	2|Bacteria	G	D-glycero-D-manno-heptose 7-phosphate metabolic process	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
SHD3_k127_4104115_8	1408164.MOLA814_00703	4.547e-63	226.0	COG0241@1|root,COG0241@2|Bacteria,1RDGR@1224|Proteobacteria,2WEA7@28216|Betaproteobacteria	28216|Betaproteobacteria	E	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_like
SHD3_k127_4104115_5	1408164.MOLA814_00702	2.387e-96	324.0	COG0176@1|root,COG0176@2|Bacteria,1QAUK@1224|Proteobacteria	1224|Proteobacteria	H	Transaldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SHD3_k127_4111641_6	1254432.SCE1572_43085	3.807e-21	99.0	COG0760@1|root,COG0760@2|Bacteria,1Q4IW@1224|Proteobacteria,43A0D@68525|delta/epsilon subdivisions,2X2FD@28221|Deltaproteobacteria,2Z2B6@29|Myxococcales	28221|Deltaproteobacteria	M	PPIC-type PPIASE domain	-	-	-	-	-	-	-	-	-	-	-	-	Rotamase_3
SHD3_k127_4111641_4	1123368.AUIS01000030_gene1253	1.835e-25	111.0	COG1522@1|root,COG1522@2|Bacteria,1NC1H@1224|Proteobacteria,1SE9N@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
SHD3_k127_4111641_10	671143.DAMO_2148	6.097e-06	56.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SHD3_k127_4111641_1	1254432.SCE1572_35555	1.275e-91	314.0	COG1801@1|root,COG1801@2|Bacteria,1N06I@1224|Proteobacteria,43BIA@68525|delta/epsilon subdivisions,2X6WP@28221|Deltaproteobacteria,2Z3DC@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SHD3_k127_4111641_0	1192034.CAP_7405	7.118e-199	627.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,42N81@68525|delta/epsilon subdivisions,2WJB0@28221|Deltaproteobacteria,2YWEI@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SHD3_k127_4111641_5	1192034.CAP_3001	1.894e-24	111.0	COG1999@1|root,COG1999@2|Bacteria	2|Bacteria	M	signal sequence binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4111641_7	404589.Anae109_0223	1.557e-15	87.0	COG4914@1|root,COG4914@2|Bacteria,1N1W1@1224|Proteobacteria,42VPD@68525|delta/epsilon subdivisions,2WS3U@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4111641_8	96561.Dole_1128	4.093e-10	63.0	COG4914@1|root,COG4914@2|Bacteria,1N1W1@1224|Proteobacteria,42VPD@68525|delta/epsilon subdivisions,2WS3U@28221|Deltaproteobacteria,2MPCT@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4117987_17	1254432.SCE1572_48480	4.231e-37	143.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1MUKF@1224|Proteobacteria,42N3S@68525|delta/epsilon subdivisions,2WJ5P@28221|Deltaproteobacteria,2YUX0@29|Myxococcales	28221|Deltaproteobacteria	S	DNA internalization-related competence protein ComEC Rec2	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
SHD3_k127_4117987_11	1192034.CAP_5359	1.147e-66	232.0	COG0634@1|root,COG0634@2|Bacteria,1NRT8@1224|Proteobacteria,42SNI@68525|delta/epsilon subdivisions,2WPFN@28221|Deltaproteobacteria,2YV3U@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
SHD3_k127_4117987_4	1254432.SCE1572_47560	1.587e-168	540.0	COG2256@1|root,COG2256@2|Bacteria,1MUVS@1224|Proteobacteria,42M9X@68525|delta/epsilon subdivisions,2WJ7E@28221|Deltaproteobacteria,2YU66@29|Myxococcales	28221|Deltaproteobacteria	L	AAA C-terminal domain	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
SHD3_k127_4117987_12	1254432.SCE1572_47570	2.641e-64	228.0	COG0325@1|root,COG0325@2|Bacteria,1MWN7@1224|Proteobacteria,42PSG@68525|delta/epsilon subdivisions,2WKYN@28221|Deltaproteobacteria,2YZQW@29|Myxococcales	28221|Deltaproteobacteria	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	yggS	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
SHD3_k127_4117987_21	1297865.APJD01000018_gene5681	5.409e-10	71.0	COG1886@1|root,COG1886@2|Bacteria,1RGWT@1224|Proteobacteria,2UC6U@28211|Alphaproteobacteria,3JYS1@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	N	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation	fliN	GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944	-	ko:K02417	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02035,ko02044	3.A.6.2,3.A.6.3	-	-	FliMN_C
SHD3_k127_4117987_16	1192034.CAP_0871	1.656e-37	149.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_0871|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4117987_5	448385.sce1051	3.349e-137	443.0	COG0152@1|root,COG0152@2|Bacteria,1MUR9@1224|Proteobacteria,42M8A@68525|delta/epsilon subdivisions,2WJY0@28221|Deltaproteobacteria,2YUIU@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the SAICAR synthetase family	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
SHD3_k127_4117987_22	867903.ThesuDRAFT_00274	1.066e-05	55.0	COG1317@1|root,COG1317@2|Bacteria	2|Bacteria	N	bacterial-type flagellum organization	fliH	-	-	ko:K02411,ko:K03223	ko02040,ko03070,map02040,map03070	M00332,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	FliH,HrpE,NolV
SHD3_k127_4117987_10	1192034.CAP_7808	3.103e-73	269.0	COG1994@1|root,COG1994@2|Bacteria,1QZHR@1224|Proteobacteria,43CIT@68525|delta/epsilon subdivisions,2X7T2@28221|Deltaproteobacteria,2Z3HE@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
SHD3_k127_4117987_14	448385.sce0012	3.884e-50	190.0	COG0745@1|root,COG0745@2|Bacteria,1N1N5@1224|Proteobacteria,42UP1@68525|delta/epsilon subdivisions,2WQAF@28221|Deltaproteobacteria,2YVKX@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_4117987_0	1192034.CAP_3119	0.0	1217.0	COG0525@1|root,COG0525@2|Bacteria,1MV7B@1224|Proteobacteria,42MPZ@68525|delta/epsilon subdivisions,2WIR9@28221|Deltaproteobacteria,2YXPT@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
SHD3_k127_4117987_1	448385.sce0013	2.354e-249	801.0	COG1807@1|root,COG1807@2|Bacteria,1NMIZ@1224|Proteobacteria,42RXF@68525|delta/epsilon subdivisions,2WNF1@28221|Deltaproteobacteria,2YV5A@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	arnT	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
SHD3_k127_4117987_15	1254432.SCE1572_00065	2.067e-41	162.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1MUI0@1224|Proteobacteria,42MCB@68525|delta/epsilon subdivisions,2WIRJ@28221|Deltaproteobacteria,2YUYH@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the precorrin methyltransferase family	hemD	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
SHD3_k127_4117987_2	1254432.SCE1572_00085	5.642e-175	568.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42N2U@68525|delta/epsilon subdivisions,2WJRR@28221|Deltaproteobacteria,2YXAZ@29|Myxococcales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	msbA1	-	-	ko:K06147,ko:K18890	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SHD3_k127_4117987_7	316067.Geob_3726	3.269e-99	353.0	COG1132@1|root,COG1132@2|Bacteria,1MUBM@1224|Proteobacteria,42NCR@68525|delta/epsilon subdivisions,2WKMY@28221|Deltaproteobacteria,43T6P@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	ABC transporter transmembrane region	-	-	-	ko:K06147,ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SHD3_k127_4117987_6	448385.sce3531	3.339e-124	411.0	29BBV@1|root,2ZYA6@2|Bacteria	2|Bacteria	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
SHD3_k127_4117987_9	671143.DAMO_0013	1.008e-82	285.0	COG0483@1|root,COG0483@2|Bacteria,2NQAS@2323|unclassified Bacteria	2|Bacteria	G	Inositol monophosphatase family	hisN	-	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
SHD3_k127_4117987_13	1304880.JAGB01000005_gene2465	2.399e-63	233.0	COG0684@1|root,COG0684@2|Bacteria,1UZ9U@1239|Firmicutes,24ADH@186801|Clostridia	186801|Clostridia	H	PFAM Dimethylmenaquinone methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
SHD3_k127_4117987_3	671143.DAMO_2001	1.669e-169	546.0	COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,2NQBV@2323|unclassified Bacteria	2|Bacteria	M	Substrate binding domain of ABC-type glycine betaine transport system	MA20_02380	-	-	ko:K05845,ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1,OpuAC
SHD3_k127_4117987_8	671143.DAMO_2002	1.917e-85	288.0	COG1125@1|root,COG1125@2|Bacteria,2NQWK@2323|unclassified Bacteria	2|Bacteria	E	ATPases associated with a variety of cellular activities	yehX	GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0031460,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0072337	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	iECED1_1282.ECED1_2573,iEcE24377_1341.EcE24377A_2418,iPC815.YPO1198	ABC_tran,CBS
SHD3_k127_4120616_0	221288.JH992901_gene4311	6.818e-78	270.0	COG2227@1|root,COG2227@2|Bacteria,1GQZP@1117|Cyanobacteria,1JKUR@1189|Stigonemataceae	1117|Cyanobacteria	H	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SHD3_k127_4120616_1	344747.PM8797T_17427	2.102e-62	233.0	COG1073@1|root,COG1073@2|Bacteria,2IYQ5@203682|Planctomycetes	203682|Planctomycetes	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SHD3_k127_4120616_3	1229780.BN381_330102	8.325e-12	70.0	COG1848@1|root,COG1848@2|Bacteria,2GUVQ@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4120616_2	1123256.KB907934_gene2365	1.536e-15	85.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_413476_1	1192034.CAP_6022	9.188e-288	905.0	COG0642@1|root,COG2205@2|Bacteria,1MUZQ@1224|Proteobacteria,42NZF@68525|delta/epsilon subdivisions,2WJNR@28221|Deltaproteobacteria,2YYGK@29|Myxococcales	28221|Deltaproteobacteria	T	Osmosensitive K+ channel His kinase sensor domain	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,GAF_3,HATPase_c,HisKA,KdpD,Usp
SHD3_k127_413476_3	1458357.BG58_18710	4.984e-66	237.0	COG2156@1|root,COG2156@2|Bacteria,1RABG@1224|Proteobacteria,2VQ72@28216|Betaproteobacteria,1K3NK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
SHD3_k127_413476_0	1192034.CAP_6024	0.0	1074.0	COG2216@1|root,COG2216@2|Bacteria,1MU7D@1224|Proteobacteria,42NGX@68525|delta/epsilon subdivisions,2WJC0@28221|Deltaproteobacteria,2YWXY@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iAF987.Gmet_2434	E1-E2_ATPase,Hydrolase
SHD3_k127_413476_2	1192034.CAP_6025	1.265e-264	826.0	COG2060@1|root,COG2060@2|Bacteria,1MV1K@1224|Proteobacteria,42NCD@68525|delta/epsilon subdivisions,2WJ03@28221|Deltaproteobacteria,2YWFC@29|Myxococcales	28221|Deltaproteobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
SHD3_k127_4140279_12	4896.SPAC57A10.07.1	3.756e-12	71.0	KOG4533@1|root,KOG4533@2759|Eukaryota,3A4VF@33154|Opisthokonta,3P3U4@4751|Fungi,3QT2Z@4890|Ascomycota,3MDXM@451866|Taphrinomycotina	4751|Fungi	S	duf218 domain protein	-	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	-	-	-	-	-	-	-	-	-	DUF218
SHD3_k127_4140279_2	1502852.FG94_05115	1.674e-119	398.0	COG2271@1|root,COG2271@2|Bacteria,1QZGJ@1224|Proteobacteria,2WBH7@28216|Betaproteobacteria,475TH@75682|Oxalobacteraceae	28216|Betaproteobacteria	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SHD3_k127_4140279_8	96561.Dole_0519	6.318e-64	235.0	COG1651@1|root,COG4243@1|root,COG1651@2|Bacteria,COG4243@2|Bacteria,1QSA7@1224|Proteobacteria,42T4Y@68525|delta/epsilon subdivisions,2WPNT@28221|Deltaproteobacteria,2MMVE@213118|Desulfobacterales	28221|Deltaproteobacteria	O	VKc	-	-	-	-	-	-	-	-	-	-	-	-	DSBA,Thioredoxin_4,VKOR
SHD3_k127_4140279_11	404589.Anae109_2838	8.715e-18	92.0	COG0526@1|root,COG0526@2|Bacteria,1QT4H@1224|Proteobacteria,4356V@68525|delta/epsilon subdivisions,2X96A@28221|Deltaproteobacteria,2Z26T@29|Myxococcales	28221|Deltaproteobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_8
SHD3_k127_4140279_6	448385.sce6201	2.103e-82	286.0	COG2885@1|root,COG2885@2|Bacteria,1Q9RC@1224|Proteobacteria,434J9@68525|delta/epsilon subdivisions,2WYWG@28221|Deltaproteobacteria,2Z0SZ@29|Myxococcales	28221|Deltaproteobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4140279_1	1254432.SCE1572_37355	1.35e-121	404.0	COG1651@1|root,COG1651@2|Bacteria,1Q3GQ@1224|Proteobacteria,43994@68525|delta/epsilon subdivisions,2X4GG@28221|Deltaproteobacteria,2YYZ6@29|Myxococcales	28221|Deltaproteobacteria	O	Vitamin K epoxide reductase family	-	-	-	-	-	-	-	-	-	-	-	-	VKOR
SHD3_k127_4140279_4	448385.sce1028	1.077e-105	365.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gt4G	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SHD3_k127_4140279_9	448385.sce2841	3.136e-36	145.0	COG2867@1|root,COG2867@2|Bacteria	2|Bacteria	I	negative regulation of translational initiation	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc,Polyketide_cyc2,START
SHD3_k127_4140279_3	234267.Acid_4374	1.977e-109	359.0	COG0588@1|root,COG0588@2|Bacteria,3Y6SZ@57723|Acidobacteria	57723|Acidobacteria	F	Phosphoglycerate mutase family	-	-	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SHD3_k127_4140279_7	309799.DICTH_0376	2.62e-69	242.0	COG1028@1|root,COG1028@2|Bacteria	309799.DICTH_0376|-	IQ	oxidoreductase activity, acting on CH-OH group of donors	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4140279_0	1499967.BAYZ01000079_gene883	1.672e-211	663.0	COG2873@1|root,COG2873@2|Bacteria,2NQN4@2323|unclassified Bacteria	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SHD3_k127_4140279_5	1313304.CALK_0524	4.533e-87	302.0	COG1897@1|root,COG1897@2|Bacteria	2|Bacteria	E	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	HTS
SHD3_k127_4155925_0	667014.Thein_0272	0.0	1068.0	COG0086@1|root,COG0086@2|Bacteria,2GHHF@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SHD3_k127_4155925_1	593750.Metfor_0192	2.607e-72	254.0	COG0500@1|root,arCOG01773@2157|Archaea,2Y131@28890|Euryarchaeota	28890|Euryarchaeota	Q	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
SHD3_k127_4155925_2	419947.MRA_0081	7.026e-47	175.0	2CYNV@1|root,32T4H@2|Bacteria,2IRMP@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SHD3_k127_4160706_5	1192034.CAP_0922	1.853e-30	124.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2X5MZ@28221|Deltaproteobacteria,2Z36F@29|Myxococcales	28221|Deltaproteobacteria	J	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SHD3_k127_4160706_1	1192034.CAP_0921	1.7e-97	328.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,2YUW4@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SHD3_k127_4160706_2	1192034.CAP_0920	2.88e-58	227.0	COG1413@1|root,COG1413@2|Bacteria,1N55Z@1224|Proteobacteria,42Q7F@68525|delta/epsilon subdivisions,2WPWV@28221|Deltaproteobacteria,2YWMA@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT,HEAT_2,HEAT_PBS
SHD3_k127_4160706_3	448385.sce1596	2.274e-42	160.0	COG0835@1|root,COG0835@2|Bacteria,1RAH1@1224|Proteobacteria,42S69@68525|delta/epsilon subdivisions,2X5TT@28221|Deltaproteobacteria,2Z060@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	cheW	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SHD3_k127_4160706_4	448385.sce1595	1.74e-38	149.0	COG0835@1|root,COG0835@2|Bacteria,1PEGB@1224|Proteobacteria,43466@68525|delta/epsilon subdivisions,2X1U3@28221|Deltaproteobacteria,2YYW0@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SHD3_k127_4160706_0	448385.sce1594	1.501e-150	486.0	COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WJ5U@28221|Deltaproteobacteria,2YU8D@29|Myxococcales	28221|Deltaproteobacteria	NT	Signal transducing histidine kinase, homodimeric domain	cheA40H	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt
SHD3_k127_4165388_3	1380394.JADL01000020_gene1815	2.084e-25	115.0	COG0745@1|root,COG0745@2|Bacteria,1MY2Z@1224|Proteobacteria,2TRFZ@28211|Alphaproteobacteria,2JPZV@204441|Rhodospirillales	204441|Rhodospirillales	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoB	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_4165388_4	1454004.AW11_01516	2.538e-12	68.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,1KQA1@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	P	YHS domain	silP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
SHD3_k127_4165388_2	641107.CDLVIII_4239	2.051e-35	151.0	COG5520@1|root,COG5520@2|Bacteria,1U8RG@1239|Firmicutes,248NT@186801|Clostridia,36H0Z@31979|Clostridiaceae	186801|Clostridia	G	dockerin type	xynC1	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_2,CBM_4_9,CBM_6,Dockerin_1,Esterase,Glyco_hydro_30,Glyco_hydro_30C,Polysacc_deac_1,RicinB_lectin_2
SHD3_k127_4165388_1	378806.STAUR_3683	4.776e-65	229.0	COG4305@1|root,COG4305@2|Bacteria,1MYW4@1224|Proteobacteria,439IT@68525|delta/epsilon subdivisions,2X4V8@28221|Deltaproteobacteria,2YZP0@29|Myxococcales	28221|Deltaproteobacteria	G	Lytic transglycolase	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	DPBB_1
SHD3_k127_4165388_0	383372.Rcas_0264	4.153e-66	240.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4178996_3	448385.sce2981	6.228e-88	303.0	COG1075@1|root,COG1075@2|Bacteria,1QTCH@1224|Proteobacteria,437VW@68525|delta/epsilon subdivisions,2WYPR@28221|Deltaproteobacteria,2YUCF@29|Myxococcales	28221|Deltaproteobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4178996_7	448385.sce8005	1.1e-44	164.0	COG1145@1|root,COG1145@2|Bacteria,1MZ6H@1224|Proteobacteria,42U8W@68525|delta/epsilon subdivisions,2X3DV@28221|Deltaproteobacteria,2YVMF@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
SHD3_k127_4178996_9	1192034.CAP_2173	2.029e-27	120.0	2ANM7@1|root,31DKH@2|Bacteria,1QAWY@1224|Proteobacteria,435CB@68525|delta/epsilon subdivisions,2WZPX@28221|Deltaproteobacteria,2Z2HJ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4178996_6	1254432.SCE1572_45995	6.977e-56	211.0	COG1413@1|root,COG1413@2|Bacteria,1QAW1@1224|Proteobacteria,43E4E@68525|delta/epsilon subdivisions,2WZPH@28221|Deltaproteobacteria,2Z2H1@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_4178996_2	448385.sce7149	2.674e-88	306.0	COG2755@1|root,COG2755@2|Bacteria,1Q3HJ@1224|Proteobacteria,439AC@68525|delta/epsilon subdivisions,2X4HW@28221|Deltaproteobacteria,2YZ1R@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_4178996_1	448385.sce8001	5.617e-129	422.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YY6R@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SHD3_k127_4178996_0	1254432.SCE1572_45975	8.307e-189	600.0	COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,42N8Y@68525|delta/epsilon subdivisions,2WIR7@28221|Deltaproteobacteria,2YTYX@29|Myxococcales	28221|Deltaproteobacteria	C	dihydrolipoamide dehydrogenase	pdhD	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
SHD3_k127_4178996_11	1169154.KB897780_gene2216	1.047e-06	62.0	COG5640@1|root,COG5640@2|Bacteria,2IAMZ@201174|Actinobacteria	201174|Actinobacteria	O	PFAM peptidase S1 and S6, chymotrypsin Hap	-	-	-	-	-	-	-	-	-	-	-	-	Ricin_B_lectin,Trypsin
SHD3_k127_4178996_13	58123.JOFJ01000018_gene4275	2.414e-06	60.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,Peptidase_M10
SHD3_k127_4178996_12	1278073.MYSTI_06674	1.439e-06	61.0	COG0457@1|root,COG1629@1|root,COG0457@2|Bacteria,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42PWS@68525|delta/epsilon subdivisions,2WKI5@28221|Deltaproteobacteria,2YU72@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TPR_8,TonB_dep_Rec
SHD3_k127_4178996_5	1192034.CAP_6942	1.354e-58	225.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4178996_4	1192034.CAP_5604	5.406e-60	220.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
SHD3_k127_4183635_3	82654.Pse7367_0585	8.112e-15	78.0	COG1357@1|root,COG1357@2|Bacteria,1G37B@1117|Cyanobacteria,1HAA6@1150|Oscillatoriales	1117|Cyanobacteria	T	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
SHD3_k127_4183635_1	1192034.CAP_1200	7.953e-79	280.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_1200|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4183635_0	1254432.SCE1572_22070	1.076e-145	474.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,42P5Y@68525|delta/epsilon subdivisions,2WJEH@28221|Deltaproteobacteria,2YXPN@29|Myxococcales	28221|Deltaproteobacteria	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SHD3_k127_4195716_5	1123072.AUDH01000001_gene2761	0.0003508	50.0	2E13Z@1|root,32WJ8@2|Bacteria,1NYI6@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4195716_1	1254432.SCE1572_14920	1.608e-43	171.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_14920|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4195716_4	243233.MCA2782	3.107e-08	68.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XDTR@135618|Methylococcales	135618|Methylococcales	G	alpha beta alpha domain I	-	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SHD3_k127_4195716_3	999141.GME_14475	3.354e-14	88.0	COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1XI27@135619|Oceanospirillales	135619|Oceanospirillales	G	phosphomannomutase	algC	-	5.4.2.2,5.4.2.8	ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SHD3_k127_4195716_0	485913.Krac_4737	7.626e-82	280.0	COG0566@1|root,COG0566@2|Bacteria,2G7XK@200795|Chloroflexi	200795|Chloroflexi	H	PFAM tRNA rRNA methyltransferase (SpoU)	-	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
SHD3_k127_4195716_2	4787.PITG_16483T0	5.566e-17	96.0	COG0515@1|root,2QUN0@2759|Eukaryota,3Q8RR@4776|Peronosporales	4776|Peronosporales	KLT	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_420659_1	1254432.SCE1572_31760	2.36e-34	153.0	COG1609@1|root,COG2208@1|root,COG1609@2|Bacteria,COG2208@2|Bacteria,1RHRV@1224|Proteobacteria,43ARR@68525|delta/epsilon subdivisions,2X65U@28221|Deltaproteobacteria,2Z0U1@29|Myxococcales	28221|Deltaproteobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3,SpoIIE
SHD3_k127_420659_0	1121403.AUCV01000045_gene1130	2.768e-49	202.0	COG0642@1|root,COG2204@1|root,COG2204@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43CHE@68525|delta/epsilon subdivisions,2X7SI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_4211833_0	1192034.CAP_5957	5.154e-149	479.0	2DBFX@1|root,2Z917@2|Bacteria,1P4PR@1224|Proteobacteria,42R0H@68525|delta/epsilon subdivisions,2WN0C@28221|Deltaproteobacteria,2YXKP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4211833_5	448385.sce0881	3.769e-27	116.0	COG2172@1|root,COG2172@2|Bacteria,1Q2UT@1224|Proteobacteria,42V6B@68525|delta/epsilon subdivisions,2WRJ9@28221|Deltaproteobacteria,2Z2FB@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase-like ATPase domain	-	-	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
SHD3_k127_4211833_2	448385.sce0882	8.163e-89	303.0	COG2148@1|root,COG2148@2|Bacteria,1MV6W@1224|Proteobacteria,42NH8@68525|delta/epsilon subdivisions,2WJMA@28221|Deltaproteobacteria,2YXRR@29|Myxococcales	28221|Deltaproteobacteria	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
SHD3_k127_4211833_1	448385.sce1301	5.51e-92	322.0	COG0438@1|root,COG0438@2|Bacteria,1R564@1224|Proteobacteria,42SAM@68525|delta/epsilon subdivisions,2WPCJ@28221|Deltaproteobacteria,2YZP2@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
SHD3_k127_4211833_4	335283.Neut_0902	7.054e-64	237.0	COG0726@1|root,COG0726@2|Bacteria,1RAPZ@1224|Proteobacteria,2WFKR@28216|Betaproteobacteria,374PZ@32003|Nitrosomonadales	28216|Betaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4211833_3	933262.AXAM01000035_gene2132	2.246e-65	250.0	COG3291@1|root,COG3291@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
SHD3_k127_4211833_6	933262.AXAM01000035_gene2132	6.097e-23	106.0	COG3291@1|root,COG3291@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
SHD3_k127_4218808_1	391625.PPSIR1_34113	4.324e-82	288.0	COG2200@1|root,COG2204@1|root,COG2200@2|Bacteria,COG2204@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2Z1P1@29|Myxococcales	28221|Deltaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
SHD3_k127_4218808_3	1192034.CAP_0018	3.094e-05	54.0	29RMJ@1|root,30CQT@2|Bacteria,1QTPA@1224|Proteobacteria,4380Z@68525|delta/epsilon subdivisions,2X3B0@28221|Deltaproteobacteria,2YV6U@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4218808_0	502025.Hoch_4790	2.261e-117	394.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YYCB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_4218808_2	472759.Nhal_1244	4.266e-58	204.0	COG1523@1|root,COG1523@2|Bacteria,1MU19@1224|Proteobacteria,1RP6F@1236|Gammaproteobacteria,1WX62@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
SHD3_k127_4219186_6	1121918.ARWE01000001_gene3170	3.562e-30	139.0	COG1520@1|root,COG4886@1|root,COG1520@2|Bacteria,COG4886@2|Bacteria,1PIDG@1224|Proteobacteria,42UM6@68525|delta/epsilon subdivisions,2WPZY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_3
SHD3_k127_4219186_2	357808.RoseRS_0421	5.441e-93	332.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_4219186_5	448385.sce5448	1.346e-31	131.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_4219186_4	1303518.CCALI_02592	5.226e-32	142.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,Response_reg,dCache_1
SHD3_k127_4219186_7	596152.DesU5LDRAFT_2790	1.114e-19	101.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2MG1U@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_4219186_1	1192034.CAP_7197	2.582e-98	330.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria,2YUZ3@29|Myxococcales	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
SHD3_k127_4219186_0	448385.sce1624	2.975e-111	379.0	COG0373@1|root,COG0373@2|Bacteria,1MU41@1224|Proteobacteria,42MUG@68525|delta/epsilon subdivisions,2WISB@28221|Deltaproteobacteria,2YWEM@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
SHD3_k127_4219186_3	1254432.SCE1572_10315	8.983e-44	169.0	COG4137@1|root,COG4137@2|Bacteria,1R3M0@1224|Proteobacteria,43DKU@68525|delta/epsilon subdivisions,2X8S0@28221|Deltaproteobacteria,2YW4U@29|Myxococcales	28221|Deltaproteobacteria	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SHD3_k127_4226735_6	1192034.CAP_0509	1.206e-40	154.0	COG2755@1|root,COG2755@2|Bacteria,1R7BU@1224|Proteobacteria,43428@68525|delta/epsilon subdivisions,2X4SY@28221|Deltaproteobacteria,2YZIV@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_4226735_0	1192034.CAP_7322	6.554e-147	485.0	COG4775@1|root,COG4775@2|Bacteria,1Q2CZ@1224|Proteobacteria,437ZA@68525|delta/epsilon subdivisions,2X399@28221|Deltaproteobacteria,2YUX9@29|Myxococcales	28221|Deltaproteobacteria	M	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
SHD3_k127_4226735_1	1254432.SCE1572_27145	1.253e-138	466.0	COG1721@1|root,COG1721@2|Bacteria,1QN1W@1224|Proteobacteria,434YE@68525|delta/epsilon subdivisions,2WZ9B@28221|Deltaproteobacteria,2Z1MQ@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
SHD3_k127_4226735_4	1254432.SCE1572_27150	1.058e-86	298.0	COG0030@1|root,COG0030@2|Bacteria,1MVNU@1224|Proteobacteria,42QAC@68525|delta/epsilon subdivisions,2WN8H@28221|Deltaproteobacteria,2YVAS@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
SHD3_k127_4226735_2	1254432.SCE1572_28180	6.726e-114	379.0	COG5653@1|root,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria,42VU5@68525|delta/epsilon subdivisions,2WSGU@28221|Deltaproteobacteria,2YX5B@29|Myxococcales	28221|Deltaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
SHD3_k127_4226735_5	1040989.AWZU01000056_gene3841	2.081e-52	209.0	COG0639@1|root,COG0639@2|Bacteria,1MUV1@1224|Proteobacteria,2V74D@28211|Alphaproteobacteria,3K3QZ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
SHD3_k127_4226735_3	1254432.SCE1572_28190	1.726e-100	342.0	COG3919@1|root,COG3919@2|Bacteria,1N13P@1224|Proteobacteria,42WGT@68525|delta/epsilon subdivisions,2WRKR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	ATP-grasp	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_3
SHD3_k127_422774_15	287.DR97_6140	2.056e-07	64.0	COG1413@1|root,COG1413@2|Bacteria,1R4SF@1224|Proteobacteria,1S2HV@1236|Gammaproteobacteria,1YF9N@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	C	HEAT repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS
SHD3_k127_422774_13	1254432.SCE1572_09880	8.807e-15	78.0	COG3868@1|root,COG4733@1|root,COG5640@1|root,COG3868@2|Bacteria,COG4733@2|Bacteria,COG5640@2|Bacteria,1QZIM@1224|Proteobacteria,43CK5@68525|delta/epsilon subdivisions,2X7UK@28221|Deltaproteobacteria,2Z12E@29|Myxococcales	28221|Deltaproteobacteria	O	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_422774_8	378806.STAUR_3433	1.109e-46	173.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SHD3_k127_422774_11	1254432.SCE1572_05290	5.839e-25	123.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_binding_2,FTP,FlgD_ig,PPC,Peptidase_M4,Peptidase_M4_C,RicinB_lectin_2,SBBP,TIG,Trypsin,VCBS
SHD3_k127_422774_2	443143.GM18_4316	3.777e-132	467.0	COG1404@1|root,COG1520@1|root,COG1404@2|Bacteria,COG1520@2|Bacteria,1MU3S@1224|Proteobacteria,42Q3Z@68525|delta/epsilon subdivisions,2WJPC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase S8 family	-	-	3.4.21.66	ko:K08651	-	-	-	-	ko00000,ko01000,ko01002,ko03110	-	-	-	Big_2,CUB,He_PIG,Peptidase_S8
SHD3_k127_422774_7	448385.sce2072	1.428e-48	190.0	COG5164@1|root,COG5164@2|Bacteria,1R0C5@1224|Proteobacteria,43CUH@68525|delta/epsilon subdivisions,2X826@28221|Deltaproteobacteria,2Z24H@29|Myxococcales	28221|Deltaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_422774_1	1254432.SCE1572_05400	0.0	1119.0	COG3661@1|root,COG3661@2|Bacteria,1MXKA@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 67 family	aguA	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010383,GO:0010410,GO:0010413,GO:0016052,GO:0016787,GO:0016798,GO:0033939,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044260,GO:0045491,GO:0045493,GO:0071554,GO:0071704,GO:1901575,GO:2000886	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
SHD3_k127_422774_5	688245.CtCNB1_2562	9.51e-81	280.0	COG3291@1|root,COG3291@2|Bacteria,1R9R7@1224|Proteobacteria,2VUZS@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Pkd domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_422774_6	448385.sce2825	1.194e-64	239.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_422774_14	309799.DICTH_1678	2.894e-10	71.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF1451,FHA,Yop-YscD_cpl
SHD3_k127_422774_16	345341.KUTG_01093	1.368e-05	57.0	COG5640@1|root,COG5640@2|Bacteria,2H3EF@201174|Actinobacteria,4EAME@85010|Pseudonocardiales	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SHD3_k127_422774_17	6500.XP_005097836.1	0.0002088	56.0	KOG4297@1|root,KOG4297@2759|Eukaryota,3AVB5@33154|Opisthokonta,3C546@33208|Metazoa,3DKG5@33213|Bilateria	33208|Metazoa	TV	C-type lectin (CTL) or carbohydrate-recognition domain (CRD)	-	GO:0003674,GO:0005488,GO:0030246	-	ko:K22244	ko05226,map05226	-	-	-	ko00000,ko00001	-	-	-	Lectin_C
SHD3_k127_422774_12	1297742.A176_06634	5.098e-17	96.0	COG1413@1|root,COG1413@2|Bacteria,1P8HR@1224|Proteobacteria,438W3@68525|delta/epsilon subdivisions,2X41M@28221|Deltaproteobacteria,2YXYY@29|Myxococcales	28221|Deltaproteobacteria	C	Lipoprotein amino terminal region	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_422774_9	502025.Hoch_0055	3.682e-42	173.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.71	ko:K01346	ko04972,ko04974,map04972,map04974	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Trypsin
SHD3_k127_422774_3	357808.RoseRS_0421	1.959e-97	330.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_422774_4	1454004.AW11_00141	3.409e-83	291.0	COG1835@1|root,COG1835@2|Bacteria,1NSVZ@1224|Proteobacteria,2VKZ5@28216|Betaproteobacteria,1KQRB@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
SHD3_k127_422774_0	448385.sce2503	0.0	1134.0	COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YUB7@29|Myxococcales	28221|Deltaproteobacteria	KL	Superfamily II DNA RNA helicases, SNF2 family	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
SHD3_k127_422774_10	1121448.DGI_2220	5.15e-32	130.0	COG0840@1|root,COG2703@1|root,COG0840@2|Bacteria,COG2703@2|Bacteria,1RBB1@1224|Proteobacteria,42RNA@68525|delta/epsilon subdivisions,2WNGN@28221|Deltaproteobacteria,2MGVG@213115|Desulfovibrionales	28221|Deltaproteobacteria	NPT	PFAM chemotaxis	-	-	-	ko:K03406,ko:K07216	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	Hemerythrin,MCPsignal,PilJ
SHD3_k127_423139_2	448385.sce3687	5.522e-06	55.0	COG0858@1|root,COG0858@2|Bacteria,1QAV6@1224|Proteobacteria,435BE@68525|delta/epsilon subdivisions,2WZNT@28221|Deltaproteobacteria,2Z2FN@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosome-binding factor A	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_423139_0	448385.sce3688	1.756e-91	316.0	COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2YWM1@29|Myxococcales	28221|Deltaproteobacteria	S	tRNA-splicing ligase RtcB	-	-	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
SHD3_k127_423139_1	886293.Sinac_4353	6.497e-20	101.0	2A8GS@1|root,30XIR@2|Bacteria,2J2JC@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4233183_9	369723.Strop_0788	1.183e-06	52.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4D8CT@85008|Micromonosporales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
SHD3_k127_4233183_4	670292.JH26_16970	2.231e-64	235.0	COG2017@1|root,COG2017@2|Bacteria,1RGXX@1224|Proteobacteria,2U93Z@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
SHD3_k127_4233183_2	1043493.BBLU01000003_gene2294	6.605e-84	298.0	COG0039@1|root,COG0039@2|Bacteria,2IB3A@201174|Actinobacteria	201174|Actinobacteria	C	lactate/malate dehydrogenase, NAD binding domain	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_N
SHD3_k127_4233183_0	518766.Rmar_0119	5.08e-182	587.0	COG1626@1|root,COG1626@2|Bacteria,4NFJW@976|Bacteroidetes,1FJT0@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	Trehalase	treA	-	3.2.1.28	ko:K01194	ko00500,ko01100,map00500,map01100	-	R00010	RC00049	ko00000,ko00001,ko00537,ko01000	-	GH37	-	Trehalase,Trehalase_Ca-bi
SHD3_k127_4233183_6	219305.MCAG_04084	1.696e-21	106.0	COG5297@1|root,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4DBZI@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 12 (cellulase H) family	celA1	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Glyco_hydro_12
SHD3_k127_4233183_3	1192034.CAP_3979	1.826e-71	259.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_3979|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4233183_7	391625.PPSIR1_07325	9.091e-15	87.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SHD3_k127_4233183_1	452637.Oter_4086	2.899e-87	310.0	COG0524@1|root,COG0524@2|Bacteria,46SCP@74201|Verrucomicrobia,3K7C2@414999|Opitutae	414999|Opitutae	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
SHD3_k127_4233183_8	66377.JOBH01000003_gene5402	6.766e-14	78.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_4254553_6	1173022.Cri9333_4340	0.0001045	55.0	COG0457@1|root,COG0457@2|Bacteria,1GC67@1117|Cyanobacteria,1HENI@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4254553_4	58123.JOFJ01000011_gene4806	4.577e-31	137.0	2DB8X@1|root,2Z7T1@2|Bacteria,2GMNE@201174|Actinobacteria,4ENRQ@85012|Streptosporangiales	201174|Actinobacteria	S	Suppressor of fused protein (SUFU)	-	-	-	-	-	-	-	-	-	-	-	-	SUFU
SHD3_k127_4254553_2	269798.CHU_2852	1.794e-39	169.0	COG3405@1|root,COG5295@1|root,COG3405@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,47KN7@768503|Cytophagia	976|Bacteroidetes	GUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
SHD3_k127_4254553_5	448385.sce5493	2.629e-07	64.0	2AN2E@1|root,31CZZ@2|Bacteria,1QA0W@1224|Proteobacteria,434RF@68525|delta/epsilon subdivisions,2WZ2M@28221|Deltaproteobacteria,2Z16X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_11
SHD3_k127_4254553_1	933262.AXAM01000035_gene2132	9.899e-67	249.0	COG3291@1|root,COG3291@2|Bacteria,1MWIT@1224|Proteobacteria,42W2M@68525|delta/epsilon subdivisions,2WRTW@28221|Deltaproteobacteria,2MKVR@213118|Desulfobacterales	28221|Deltaproteobacteria	M	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD,VCBS
SHD3_k127_4254553_0	880070.Cycma_4136	2.147e-76	273.0	COG4948@1|root,COG4948@2|Bacteria,4NE9A@976|Bacteroidetes,47NDY@768503|Cytophagia	976|Bacteroidetes	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MR_MLE_C,MR_MLE_N
SHD3_k127_4254553_3	398512.JQKC01000013_gene1447	2.738e-33	145.0	COG4447@1|root,COG4447@2|Bacteria,1UU3Y@1239|Firmicutes,24C6F@186801|Clostridia,3WMYB@541000|Ruminococcaceae	186801|Clostridia	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4256120_1	573413.Spirs_3049	7.911e-34	141.0	COG0477@1|root,COG2814@2|Bacteria,2JA5Q@203691|Spirochaetes	203691|Spirochaetes	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SHD3_k127_4256120_0	1089544.KB912942_gene2691	5.824e-60	231.0	COG1032@1|root,COG1032@2|Bacteria,2GPWR@201174|Actinobacteria	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_4256120_2	1280941.HY2_16625	6.466e-07	55.0	2DHQX@1|root,300M5@2|Bacteria,1Q6CH@1224|Proteobacteria,2V6V7@28211|Alphaproteobacteria,43ZY3@69657|Hyphomonadaceae	28211|Alphaproteobacteria	S	Fe-S-cluster oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SHD3_k127_4257645_0	1167006.UWK_01107	4.27e-123	407.0	COG2848@1|root,COG2848@2|Bacteria,1NAFG@1224|Proteobacteria,42NH7@68525|delta/epsilon subdivisions,2WJJM@28221|Deltaproteobacteria,2MI2J@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Uncharacterised ACR (DUF711)	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
SHD3_k127_4257645_2	1167006.UWK_01106	1.264e-30	133.0	COG2716@1|root,COG2716@2|Bacteria,1RB6J@1224|Proteobacteria,42RTX@68525|delta/epsilon subdivisions,2WPGC@28221|Deltaproteobacteria,2MJZX@213118|Desulfobacterales	28221|Deltaproteobacteria	E	ACT domain	-	-	-	ko:K03567	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	ACT_6
SHD3_k127_4257645_1	1192034.CAP_5182	1.648e-46	188.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_4257645_3	1177179.A11A3_15147	7.341e-25	114.0	COG0454@1|root,COG0456@2|Bacteria,1N4JC@1224|Proteobacteria,1SDHV@1236|Gammaproteobacteria,1XMSM@135619|Oceanospirillales	135619|Oceanospirillales	K	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SHD3_k127_4257645_4	1313172.YM304_13950	8.029e-20	105.0	COG4188@1|root,COG4188@2|Bacteria,2GZAJ@201174|Actinobacteria	201174|Actinobacteria	S	Platelet-activating factor acetylhydrolase, isoform II	-	-	-	-	-	-	-	-	-	-	-	-	PAF-AH_p_II
SHD3_k127_4257645_6	1281779.H009_17393	7.597e-09	69.0	COG4188@1|root,COG4188@2|Bacteria,1MW2N@1224|Proteobacteria,2U1F7@28211|Alphaproteobacteria,4BMHE@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,PAF-AH_p_II
SHD3_k127_4270738_1	1254432.SCE1572_10170	1.38e-94	326.0	COG0741@1|root,COG1388@1|root,COG3064@1|root,COG0741@2|Bacteria,COG1388@2|Bacteria,COG3064@2|Bacteria,1MWKE@1224|Proteobacteria,42MWF@68525|delta/epsilon subdivisions,2WKAQ@28221|Deltaproteobacteria,2Z2XM@29|Myxococcales	28221|Deltaproteobacteria	M	Lysin motif	-	-	-	ko:K08307	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	LysM,SLT
SHD3_k127_4270738_0	1268237.G114_01789	2.08e-209	663.0	COG0114@1|root,COG0114@2|Bacteria,1MUQI@1224|Proteobacteria,1RNUS@1236|Gammaproteobacteria,1Y3VA@135624|Aeromonadales	135624|Aeromonadales	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	-	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
SHD3_k127_4270738_2	1297742.A176_04405	4.087e-57	218.0	298PG@1|root,2ZVTY@2|Bacteria,1RIKV@1224|Proteobacteria,433IU@68525|delta/epsilon subdivisions,2WXIH@28221|Deltaproteobacteria,2YUYB@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4270738_4	983920.Y88_1296	5.686e-29	128.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2U0BU@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
SHD3_k127_4270738_3	1122921.KB898190_gene1404	2.591e-38	153.0	COG0500@1|root,COG2226@2|Bacteria,1V45D@1239|Firmicutes,4HG4Y@91061|Bacilli,274IB@186822|Paenibacillaceae	91061|Bacilli	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_4270738_5	43354.JOIJ01000007_gene1579	4.404e-09	60.0	COG0789@1|root,COG0789@2|Bacteria,2GPCQ@201174|Actinobacteria,4DZ8U@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SHD3_k127_4285580_3	640081.Dsui_3027	2.061e-33	130.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2VJT0@28216|Betaproteobacteria,2KVAX@206389|Rhodocyclales	206389|Rhodocyclales	C	Belongs to the NiFe NiFeSe hydrogenase large subunit family	hoxH	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
SHD3_k127_4285580_4	876269.ARWA01000001_gene1529	1.316e-28	123.0	COG0680@1|root,COG0680@2|Bacteria,1MZE1@1224|Proteobacteria,2UJ8E@28211|Alphaproteobacteria,3NCCE@45404|Beijerinckiaceae	28211|Alphaproteobacteria	C	hydrogenase maturation protease	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4285580_9	1191523.MROS_2486	4.723e-13	74.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.13.3	ko:K02282,ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko02044	-	-	-	AAA_31,CheW,GGDEF,H-kinase_dim,HATPase_c,Hpt,Response_reg
SHD3_k127_4285580_0	935845.JADQ01000050_gene3903	1.108e-179	571.0	COG2152@1|root,COG2152@2|Bacteria,1TNYI@1239|Firmicutes,4HA02@91061|Bacilli,26QPI@186822|Paenibacillaceae	91061|Bacilli	G	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose	unk1	-	2.4.1.281	ko:K16212	-	-	R09943	RC00049	ko00000,ko01000	-	-	-	Glyco_hydro_130
SHD3_k127_4285580_5	448385.sce6967	1.671e-26	119.0	COG2204@1|root,COG2204@2|Bacteria,1NABF@1224|Proteobacteria,43C0I@68525|delta/epsilon subdivisions,2X7B5@28221|Deltaproteobacteria,2Z3KD@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_4285580_7	378806.STAUR_4538	3.13e-19	97.0	COG0745@1|root,COG0745@2|Bacteria,1MZ7D@1224|Proteobacteria,42VVV@68525|delta/epsilon subdivisions,2WRBW@28221|Deltaproteobacteria,2YVNP@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_4285580_1	404589.Anae109_2150	8.167e-56	207.0	COG0702@1|root,COG0702@2|Bacteria,1PGSR@1224|Proteobacteria,430YP@68525|delta/epsilon subdivisions,2WVUA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
SHD3_k127_4285580_6	479433.Caci_6206	7.668e-25	117.0	2EFBW@1|root,3394U@2|Bacteria,2H758@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4285580_2	1254432.SCE1572_31745	1.308e-46	187.0	COG1609@1|root,COG2208@1|root,COG1609@2|Bacteria,COG2208@2|Bacteria,1RHRV@1224|Proteobacteria,43ARR@68525|delta/epsilon subdivisions,2X65U@28221|Deltaproteobacteria,2Z0U1@29|Myxococcales	28221|Deltaproteobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3,SpoIIE
SHD3_k127_4285580_10	1206741.BAFX01000031_gene7673	1.502e-05	56.0	COG0515@1|root,COG0515@2|Bacteria,2GJTV@201174|Actinobacteria,4FVEP@85025|Nocardiaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,TPR_10
SHD3_k127_429773_1	1121382.JQKG01000089_gene4588	6.036e-42	158.0	COG1487@1|root,COG1487@2|Bacteria	2|Bacteria	S	nuclease activity	-	-	-	ko:K18828	-	-	-	-	ko00000,ko01000,ko02048,ko03016	-	-	-	PIN
SHD3_k127_429773_3	251221.35211407	3.316e-11	67.0	COG3905@1|root,COG3905@2|Bacteria,1GAZS@1117|Cyanobacteria	1117|Cyanobacteria	K	Ribbon-helix-helix protein, copG family	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SHD3_k127_429773_0	768671.ThimaDRAFT_4171	5.447e-54	207.0	29QS6@1|root,30BS1@2|Bacteria,1REGY@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_429773_4	680198.SCAB_11951	0.0008767	48.0	COG0662@1|root,COG0662@2|Bacteria,2IQFZ@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
SHD3_k127_429773_2	391625.PPSIR1_34113	2.991e-29	123.0	COG2200@1|root,COG2204@1|root,COG2200@2|Bacteria,COG2204@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2Z1P1@29|Myxococcales	28221|Deltaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
SHD3_k127_430055_3	452637.Oter_2603	1.988e-75	258.0	COG2864@1|root,COG2864@2|Bacteria	2|Bacteria	C	formate dehydrogenase	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
SHD3_k127_430055_1	1121920.AUAU01000001_gene2269	7.588e-149	495.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	2|Bacteria	C	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
SHD3_k127_430055_4	644282.Deba_1371	5.004e-60	226.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,43B2Q@68525|delta/epsilon subdivisions,2WK38@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
SHD3_k127_430055_2	1211115.ALIQ01000015_gene2282	1.346e-88	301.0	COG3865@1|root,COG3865@2|Bacteria,1N7IY@1224|Proteobacteria,2U993@28211|Alphaproteobacteria,3NBAH@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
SHD3_k127_430055_8	1123251.ATWM01000003_gene1150	2.599e-11	66.0	2DSUP@1|root,33HGU@2|Bacteria,2GV46@201174|Actinobacteria	201174|Actinobacteria	-	-	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_430055_5	314278.NB231_16453	5.363e-50	185.0	COG1848@1|root,COG1848@2|Bacteria,1RK9K@1224|Proteobacteria,1SBYF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_430055_0	404589.Anae109_3067	1.122e-151	504.0	COG1948@1|root,COG4880@2|Bacteria,1PQKR@1224|Proteobacteria,438JJ@68525|delta/epsilon subdivisions,2X3U8@28221|Deltaproteobacteria,2YX4D@29|Myxococcales	28221|Deltaproteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SHD3_k127_430055_6	555079.Toce_1939	1.197e-16	87.0	COG2445@1|root,COG2445@2|Bacteria,1V8S2@1239|Firmicutes,24J9G@186801|Clostridia,42GKZ@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
SHD3_k127_430055_7	1121468.AUBR01000039_gene1934	4.233e-14	79.0	COG1669@1|root,COG1669@2|Bacteria,1VBHH@1239|Firmicutes,24JZE@186801|Clostridia	186801|Clostridia	S	DNA polymerase beta domain protein region	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
SHD3_k127_430055_9	378806.STAUR_3710	3.094e-08	61.0	2AGCS@1|root,316IF@2|Bacteria,1PXN9@1224|Proteobacteria,43EI7@68525|delta/epsilon subdivisions,2WZ12@28221|Deltaproteobacteria,2Z139@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4304889_27	1131269.AQVV01000005_gene377	1.239e-13	83.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_4304889_22	1352941.M877_08995	3.406e-27	127.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K21789	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119,R11671	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SHD3_k127_4304889_15	1304880.JAGB01000001_gene34	7.137e-79	279.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SHD3_k127_4304889_29	153721.MYP_4264	5.116e-08	59.0	COG0236@1|root,COG0236@2|Bacteria,4NSFU@976|Bacteroidetes,47S6H@768503|Cytophagia	976|Bacteroidetes	IQ	Phosphopantetheine attachment site	acpP2	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SHD3_k127_4304889_13	448385.sce3829	2.214e-87	307.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce3829|-	KLT	protein kinase activity	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	-
SHD3_k127_4304889_18	448385.sce6925	1.536e-52	205.0	COG4325@1|root,COG4325@2|Bacteria,1QKIM@1224|Proteobacteria,43411@68525|delta/epsilon subdivisions,2X4JG@28221|Deltaproteobacteria,2YZ4U@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
SHD3_k127_4304889_30	886293.Sinac_6110	3.657e-06	55.0	COG1254@1|root,COG1254@2|Bacteria,2J1IX@203682|Planctomycetes	203682|Planctomycetes	C	Belongs to the acylphosphatase family	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
SHD3_k127_4304889_20	189753.AXAS01000105_gene8002	2.704e-48	191.0	2CAM1@1|root,301FE@2|Bacteria,1RJ36@1224|Proteobacteria,2U473@28211|Alphaproteobacteria,3JWV8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase
SHD3_k127_4304889_12	596151.DesfrDRAFT_1651	3.189e-100	340.0	COG0306@1|root,COG0306@2|Bacteria,1MVXK@1224|Proteobacteria,42Q5K@68525|delta/epsilon subdivisions,2X5HI@28221|Deltaproteobacteria,2M950@213115|Desulfovibrionales	28221|Deltaproteobacteria	P	PFAM phosphate transporter	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SHD3_k127_4304889_14	378806.STAUR_1088	6.211e-79	279.0	COG1807@1|root,COG1807@2|Bacteria,1R77I@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_4304889_4	1254432.SCE1572_10535	3.553e-162	522.0	COG0206@1|root,COG0206@2|Bacteria,1MV2X@1224|Proteobacteria,42MHK@68525|delta/epsilon subdivisions,2WJAZ@28221|Deltaproteobacteria,2YTTW@29|Myxococcales	28221|Deltaproteobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
SHD3_k127_4304889_2	1192034.CAP_7154	9.449e-201	633.0	COG0849@1|root,COG0849@2|Bacteria,1MUSR@1224|Proteobacteria,42MS2@68525|delta/epsilon subdivisions,2WIQ0@28221|Deltaproteobacteria,2YTZH@29|Myxococcales	28221|Deltaproteobacteria	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
SHD3_k127_4304889_26	156889.Mmc1_0749	1.922e-16	93.0	COG1589@1|root,COG1589@2|Bacteria	2|Bacteria	D	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly	ftsQ	GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047	6.3.2.4	ko:K01921,ko:K03589,ko:K06438	ko00473,ko00550,ko01100,ko01502,ko04112,map00473,map00550,map01100,map01502,map04112	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	FtsQ,POTRA_1
SHD3_k127_4304889_1	1254432.SCE1572_10520	7.673e-216	683.0	COG0773@1|root,COG0773@2|Bacteria,1MV68@1224|Proteobacteria,42MMP@68525|delta/epsilon subdivisions,2WK50@28221|Deltaproteobacteria,2YTUP@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SHD3_k127_4304889_10	1254432.SCE1572_10515	3.664e-110	368.0	COG0707@1|root,COG0707@2|Bacteria,1MVIB@1224|Proteobacteria,42ME1@68525|delta/epsilon subdivisions,2WJNY@28221|Deltaproteobacteria,2YWEZ@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
SHD3_k127_4304889_5	1192034.CAP_7158	1.358e-145	478.0	COG0772@1|root,COG0772@2|Bacteria,1MVDB@1224|Proteobacteria,42MG2@68525|delta/epsilon subdivisions,2WJ01@28221|Deltaproteobacteria,2YTX5@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
SHD3_k127_4304889_7	1254432.SCE1572_10505	3.711e-141	460.0	COG0771@1|root,COG0771@2|Bacteria,1MVYD@1224|Proteobacteria,42MJY@68525|delta/epsilon subdivisions,2WJAQ@28221|Deltaproteobacteria,2YU89@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	AlaDh_PNT_C,FAD_binding_3,Mur_ligase_C,Mur_ligase_M,NAD_binding_8
SHD3_k127_4304889_3	1192034.CAP_7160	5.901e-169	539.0	COG0472@1|root,COG0472@2|Bacteria,1MUTK@1224|Proteobacteria,42MCP@68525|delta/epsilon subdivisions,2WJDS@28221|Deltaproteobacteria,2YWXN@29|Myxococcales	28221|Deltaproteobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	iAF987.Gmet_0409	Glycos_transf_4,MraY_sig1
SHD3_k127_4304889_9	1254432.SCE1572_43050	3.104e-113	386.0	COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,42MXF@68525|delta/epsilon subdivisions,2WIJZ@28221|Deltaproteobacteria,2YXRU@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SHD3_k127_4304889_6	1192034.CAP_7161	1.007e-144	489.0	COG0769@1|root,COG0769@2|Bacteria,1MU6P@1224|Proteobacteria,42NKY@68525|delta/epsilon subdivisions,2WJJG@28221|Deltaproteobacteria,2YU1E@29|Myxococcales	28221|Deltaproteobacteria	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
SHD3_k127_4304889_0	448385.sce1659	3.178e-246	786.0	COG0768@1|root,COG0768@2|Bacteria,1MUNY@1224|Proteobacteria,42M1T@68525|delta/epsilon subdivisions,2WK0W@28221|Deltaproteobacteria,2YTT3@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
SHD3_k127_4304889_11	1254432.SCE1572_10480	3.636e-102	342.0	COG0275@1|root,COG0275@2|Bacteria,1MUT4@1224|Proteobacteria,42N5Q@68525|delta/epsilon subdivisions,2WJ8J@28221|Deltaproteobacteria,2YUXX@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
SHD3_k127_4304889_17	1254432.SCE1572_10475	8.76e-55	196.0	COG2001@1|root,COG2001@2|Bacteria,1RHCG@1224|Proteobacteria,42TRZ@68525|delta/epsilon subdivisions,2WQRI@28221|Deltaproteobacteria,2YYCH@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
SHD3_k127_4304889_31	247490.KSU1_D0997	5.664e-05	49.0	COG4412@1|root,COG4412@2|Bacteria	2|Bacteria	S	peptidase activity, acting on L-amino acid peptides	ina	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Peptidase_M6
SHD3_k127_4304889_21	448385.sce7091	1.503e-43	168.0	COG1385@1|root,COG1385@2|Bacteria,1MXCU@1224|Proteobacteria,42R1A@68525|delta/epsilon subdivisions,2WMV6@28221|Deltaproteobacteria,2YVVD@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
SHD3_k127_4304889_25	1123276.KB893268_gene4846	1.3e-22	102.0	COG0818@1|root,COG0818@2|Bacteria,4NQ39@976|Bacteroidetes,47QV2@768503|Cytophagia	976|Bacteroidetes	M	PFAM diacylglycerol kinase	dgkA	-	2.7.1.107,2.7.1.66	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	-	R02240,R05626	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DAGK_prokar
SHD3_k127_4304889_8	1254432.SCE1572_02815	4.551e-115	398.0	COG0729@1|root,COG0729@2|Bacteria,1MUKM@1224|Proteobacteria,42MB2@68525|delta/epsilon subdivisions,2WJAF@28221|Deltaproteobacteria,2YVJQ@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	ko:K07277,ko:K07278	-	-	-	-	ko00000,ko02000,ko03029	1.B.33,1.B.33.2.4	-	-	Bac_surface_Ag,POTRA,POTRA_TamA_1
SHD3_k127_4304889_19	448385.sce4535	4.971e-50	199.0	COG2911@1|root,COG2911@2|Bacteria,1MUVD@1224|Proteobacteria,42PSZ@68525|delta/epsilon subdivisions,2WMBH@28221|Deltaproteobacteria,2YVSB@29|Myxococcales	28221|Deltaproteobacteria	S	TamB, inner membrane protein subunit of TAM complex	-	-	-	ko:K09800	-	-	-	-	ko00000,ko02000	-	-	-	TamB
SHD3_k127_4306912_0	1254432.SCE1572_51105	2.792e-159	522.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_4306912_3	103733.JNYO01000002_gene394	7.388e-34	139.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,4E1UW@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SHD3_k127_4306912_4	1242864.D187_002495	4.954e-07	61.0	2EIZM@1|root,33CQT@2|Bacteria,1P1YR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4306912_2	1192034.CAP_8393	5.5e-67	240.0	COG0611@1|root,COG0611@2|Bacteria,1MU9X@1224|Proteobacteria,42MYJ@68525|delta/epsilon subdivisions,2WNGE@28221|Deltaproteobacteria,2YVMB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
SHD3_k127_4306912_1	1254432.SCE1572_02910	2.544e-124	409.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42MZW@68525|delta/epsilon subdivisions,2WIV1@28221|Deltaproteobacteria,2YUVS@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PocR
SHD3_k127_432171_3	1121272.KB903292_gene3794	2.131e-08	60.0	COG1595@1|root,COG1595@2|Bacteria,2IHWH@201174|Actinobacteria,4DD9V@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigC	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_432171_1	1521187.JPIM01000167_gene1704	3.527e-32	142.0	COG0457@1|root,COG1404@1|root,COG0457@2|Bacteria,COG1404@2|Bacteria,2G8UU@200795|Chloroflexi,3759F@32061|Chloroflexia	32061|Chloroflexia	O	PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_4,Kelch_5,Peptidase_S8
SHD3_k127_432171_4	33898.JRHJ01000024_gene6680	0.0003531	54.0	COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31,PD40,WD40
SHD3_k127_432171_0	1265505.ATUG01000001_gene3021	4.045e-69	265.0	COG1404@1|root,COG3291@1|root,COG4870@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,COG4870@2|Bacteria,1N8Z7@1224|Proteobacteria,43AX0@68525|delta/epsilon subdivisions,2X6B7@28221|Deltaproteobacteria,2MPH8@213118|Desulfobacterales	28221|Deltaproteobacteria	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	PKD,Peptidase_C1
SHD3_k127_432171_2	1123508.JH636440_gene2948	4.011e-15	85.0	2E1HA@1|root,32WVF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_432679_0	448385.sce7031	0.0	1274.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,1MW8K@1224|Proteobacteria,43956@68525|delta/epsilon subdivisions,2X4BH@28221|Deltaproteobacteria,2YYP3@29|Myxococcales	28221|Deltaproteobacteria	S	Protein containing a von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,VIT,VWA_3
SHD3_k127_432679_2	234267.Acid_0301	1.805e-107	360.0	COG0123@1|root,COG0123@2|Bacteria,3Y5CR@57723|Acidobacteria	57723|Acidobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SHD3_k127_432679_4	1254432.SCE1572_34455	8.651e-28	123.0	COG0779@1|root,COG0779@2|Bacteria,1RDP2@1224|Proteobacteria,42THF@68525|delta/epsilon subdivisions,2WQ0W@28221|Deltaproteobacteria,2Z300@29|Myxococcales	28221|Deltaproteobacteria	J	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
SHD3_k127_432679_1	1192034.CAP_7326	2.795e-147	470.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2YUJG@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SHD3_k127_432679_3	1254432.SCE1572_34450	1.851e-93	312.0	COG0195@1|root,COG0195@2|Bacteria,1MWT7@1224|Proteobacteria,42MUW@68525|delta/epsilon subdivisions,2WIXI@28221|Deltaproteobacteria,2YUJG@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	HHH_5,KH_5,NusA_N,S1
SHD3_k127_432679_6	1123267.JONN01000001_gene793	5.178e-11	70.0	COG2740@1|root,COG2740@2|Bacteria,1RHPR@1224|Proteobacteria,2U9RY@28211|Alphaproteobacteria,2K2B7@204457|Sphingomonadales	204457|Sphingomonadales	K	Nucleic-acid-binding protein	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
SHD3_k127_4326995_2	404589.Anae109_1823	6.751e-53	201.0	COG0484@1|root,COG0484@2|Bacteria,1QYGD@1224|Proteobacteria,43CCI@68525|delta/epsilon subdivisions,2X7NG@28221|Deltaproteobacteria,2Z1CZ@29|Myxococcales	28221|Deltaproteobacteria	C	TIGRFAM cytochrome C family protein	-	-	-	-	-	-	-	-	-	-	-	-	GSu_C4xC__C2xCH
SHD3_k127_4326995_1	502025.Hoch_6280	5.931e-53	204.0	COG3005@1|root,COG3005@2|Bacteria,1R03H@1224|Proteobacteria,43CQK@68525|delta/epsilon subdivisions,2X7Y1@28221|Deltaproteobacteria,2Z1GR@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
SHD3_k127_4326995_4	290397.Adeh_0837	9.211e-39	156.0	28PU4@1|root,2ZCF6@2|Bacteria,1RBK2@1224|Proteobacteria,43B3E@68525|delta/epsilon subdivisions,2X6H4@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4326995_0	1121920.AUAU01000001_gene2269	1.486e-204	658.0	COG2864@1|root,COG2864@2|Bacteria,3Y6QW@57723|Acidobacteria	2|Bacteria	C	Prokaryotic cytochrome b561	cbcY	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_c3_2,Cytochrome_C7,Ni_hydr_CYTB,Paired_CXXCH_1,Rhodanese
SHD3_k127_4326995_5	404589.Anae109_1837	1.631e-16	94.0	COG3043@1|root,COG3043@2|Bacteria,1RG8Q@1224|Proteobacteria,42S2W@68525|delta/epsilon subdivisions,2WNP8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	cytochrome c	pccJ	-	-	-	-	-	-	-	-	-	-	-	Paired_CXXCH_1
SHD3_k127_4326995_3	867845.KI911784_gene2789	8.727e-39	164.0	COG4585@1|root,COG5000@1|root,COG4585@2|Bacteria,COG5000@2|Bacteria,2G6F0@200795|Chloroflexi,377HR@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA_3,sCache_3_2
SHD3_k127_4327431_0	1254432.SCE1572_15050	2.444e-76	286.0	COG0842@1|root,COG1131@1|root,COG1716@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,COG1716@2|Bacteria,1MX27@1224|Proteobacteria	1224|Proteobacteria	TV	ABC-type multidrug transport system ATPase component	-	-	-	ko:K21397	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA
SHD3_k127_4327431_1	266117.Rxyl_2282	1.66e-41	164.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4CU1S@84995|Rubrobacteria	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4327861_2	1201290.M902_0556	1.808e-06	58.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,RCC1_2
SHD3_k127_4327861_3	1192034.CAP_1238	1.302e-05	55.0	COG4733@1|root,COG4935@1|root,COG5184@1|root,COG4733@2|Bacteria,COG4935@2|Bacteria,COG5184@2|Bacteria,1QW0V@1224|Proteobacteria,42U6C@68525|delta/epsilon subdivisions,2WQX8@28221|Deltaproteobacteria,2Z3N3@29|Myxococcales	28221|Deltaproteobacteria	DOZ	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_2,DUF4215
SHD3_k127_4327861_1	717606.PaecuDRAFT_4666	1.958e-17	88.0	COG2159@1|root,COG2159@2|Bacteria,1VRJ3@1239|Firmicutes,4HUMG@91061|Bacilli,26VK3@186822|Paenibacillaceae	91061|Bacilli	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
SHD3_k127_4335134_1	502025.Hoch_2100	2.342e-186	598.0	COG4770@1|root,COG4799@1|root,COG4770@2|Bacteria,COG4799@2|Bacteria,1P6RE@1224|Proteobacteria,43A2M@68525|delta/epsilon subdivisions,2X1XW@28221|Deltaproteobacteria,2YX2T@29|Myxococcales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase, central region	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
SHD3_k127_4335134_0	1089545.KB913037_gene3625	2.864e-195	634.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,2GJF7@201174|Actinobacteria,4E7JT@85010|Pseudonocardiales	201174|Actinobacteria	G	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,RicinB_lectin_2
SHD3_k127_4335134_5	402777.KB235898_gene5702	3.299e-06	58.0	COG3291@1|root,COG4675@1|root,COG5276@1|root,COG3291@2|Bacteria,COG4675@2|Bacteria,COG5276@2|Bacteria	2|Bacteria	M	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF859,LVIVD,Laminin_G_3
SHD3_k127_4335134_3	290397.Adeh_3454	2.278e-57	211.0	2BIM8@1|root,32CU6@2|Bacteria,1P1YI@1224|Proteobacteria,4353N@68525|delta/epsilon subdivisions,2WZEN@28221|Deltaproteobacteria,2Z1Z6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4335134_4	1380390.JIAT01000012_gene3108	7.234e-19	94.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	3.6.3.44	ko:K06147,ko:K18104	ko01501,ko02010,map01501,map02010	M00700	-	-	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	3.A.1.106,3.A.1.109,3.A.1.117,3.A.1.123,3.A.1.21	-	-	ABC_membrane,ABC_tran
SHD3_k127_4335134_2	1254432.SCE1572_44880	1.792e-138	453.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
SHD3_k127_4356552_1	448385.sce2918	1.605e-156	511.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
SHD3_k127_4356552_2	404589.Anae109_2808	1.735e-109	362.0	COG2085@1|root,COG2085@2|Bacteria,1RBKZ@1224|Proteobacteria	1224|Proteobacteria	S	NADP Oxidoreductase	-	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
SHD3_k127_4356552_0	1267533.KB906734_gene4428	3.287e-166	540.0	COG2133@1|root,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	manA5	-	3.2.1.51,3.2.1.78	ko:K01206,ko:K01218	ko00051,ko00511,ko02024,map00051,map00511,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000,ko04147	-	GH26,GH29	-	Alpha_L_fucos,Cytochrome_C554,Glyco_hydro_26,PA14,RsgI_N
SHD3_k127_4356552_3	1267535.KB906767_gene1576	4.58e-90	312.0	COG2010@1|root,COG2010@2|Bacteria,3Y7CN@57723|Acidobacteria,2JK7I@204432|Acidobacteriia	204432|Acidobacteriia	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SHD3_k127_4356552_5	502025.Hoch_5250	1.336e-40	158.0	COG4758@1|root,COG4758@2|Bacteria,1RANH@1224|Proteobacteria	1224|Proteobacteria	S	Cell wall-active antibiotics response 4TMS YvqF	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
SHD3_k127_4356552_7	448385.sce6450	5.689e-07	59.0	COG4103@1|root,COG4103@2|Bacteria	2|Bacteria	T	Tellurite resistance protein TerB	-	-	-	ko:K05801	-	-	-	-	ko00000,ko03110	-	-	-	DnaJ,TerB
SHD3_k127_4356552_4	1499967.BAYZ01000120_gene3420	1.999e-51	191.0	COG2020@1|root,COG2020@2|Bacteria,2NR07@2323|unclassified Bacteria	2|Bacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SHD3_k127_4363946_2	1163409.UUA_03463	9.383e-209	666.0	COG1132@1|root,COG1132@2|Bacteria,1MXC2@1224|Proteobacteria,1RZQR@1236|Gammaproteobacteria,1XCEP@135614|Xanthomonadales	135614|Xanthomonadales	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_tran
SHD3_k127_4363946_1	1297742.A176_04954	0.0	1132.0	COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,42MRQ@68525|delta/epsilon subdivisions,2WJ3E@28221|Deltaproteobacteria,2YU4U@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
SHD3_k127_4363946_9	1254432.SCE1572_22320	1.271e-98	327.0	COG1801@1|root,COG1801@2|Bacteria,1N66P@1224|Proteobacteria,42U3V@68525|delta/epsilon subdivisions,2WQYP@28221|Deltaproteobacteria,2Z2V4@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
SHD3_k127_4363946_19	717785.HYPMC_1163	7.704e-06	57.0	COG3743@1|root,COG3743@2|Bacteria,1N76A@1224|Proteobacteria,2UFVP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	rRNA binding	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	-
SHD3_k127_4363946_4	1192034.CAP_7078	1.043e-168	547.0	COG0815@1|root,COG0815@2|Bacteria,1MUBU@1224|Proteobacteria,42MPS@68525|delta/epsilon subdivisions,2WIUD@28221|Deltaproteobacteria,2YVAG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
SHD3_k127_4363946_6	1192034.CAP_7076	1.719e-145	473.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,439TT@68525|delta/epsilon subdivisions,2X575@28221|Deltaproteobacteria,2Z07H@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_4363946_10	448385.sce3703	1.021e-97	335.0	COG1104@1|root,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria	1224|Proteobacteria	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
SHD3_k127_4363946_13	1192034.CAP_7074	2.146e-59	216.0	COG0566@1|root,COG0566@2|Bacteria,1MWCM@1224|Proteobacteria,42MZF@68525|delta/epsilon subdivisions,2WPA6@28221|Deltaproteobacteria,2YVGB@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
SHD3_k127_4363946_12	1254432.SCE1572_22290	9.92e-72	249.0	COG0284@1|root,COG0284@2|Bacteria,1MW2C@1224|Proteobacteria,42N5N@68525|delta/epsilon subdivisions,2WMJ5@28221|Deltaproteobacteria,2YV59@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)	pyrF	GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
SHD3_k127_4363946_14	448385.sce3700	5.994e-44	169.0	29Z4I@1|root,30M26@2|Bacteria,1QAWT@1224|Proteobacteria,435CA@68525|delta/epsilon subdivisions,2WZPW@28221|Deltaproteobacteria,2Z2HH@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4363946_18	404589.Anae109_0748	9.141e-26	124.0	COG4669@1|root,COG4669@2|Bacteria,1N69F@1224|Proteobacteria,42T6F@68525|delta/epsilon subdivisions,2WPNY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Secretory protein of YscJ/FliF family	nolT	-	-	ko:K03222	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	YscJ_FliF
SHD3_k127_4363946_5	448385.sce3962	5.619e-166	537.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce3962|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4363946_0	1192034.CAP_5311	0.0	1455.0	COG0457@1|root,COG4760@1|root,COG0457@2|Bacteria,COG4760@2|Bacteria,1QZT2@1224|Proteobacteria,4331A@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4363946_11	1254432.SCE1572_25795	8.24e-86	293.0	COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,42Q52@68525|delta/epsilon subdivisions,2WJ3S@28221|Deltaproteobacteria,2YV3I@29|Myxococcales	28221|Deltaproteobacteria	V	LD-carboxypeptidase	-	-	3.4.17.13	ko:K01297	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_S66
SHD3_k127_4363946_7	448385.sce4260	7.744e-103	342.0	COG0204@1|root,COG0204@2|Bacteria,1R9IG@1224|Proteobacteria,42T29@68525|delta/epsilon subdivisions,2WPJ8@28221|Deltaproteobacteria,2YUTC@29|Myxococcales	28221|Deltaproteobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
SHD3_k127_4363946_8	448385.sce4259	1.295e-102	356.0	COG0451@1|root,COG0451@2|Bacteria,1N8PG@1224|Proteobacteria,42TCH@68525|delta/epsilon subdivisions,2WPEI@28221|Deltaproteobacteria,2YU8R@29|Myxococcales	28221|Deltaproteobacteria	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SHD3_k127_4363946_3	1192034.CAP_8100	9.865e-169	539.0	COG0014@1|root,COG0014@2|Bacteria,1MUGJ@1224|Proteobacteria,42ME0@68525|delta/epsilon subdivisions,2WJB8@28221|Deltaproteobacteria,2YU1V@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SHD3_k127_4363946_15	1254432.SCE1572_22165	3.056e-38	155.0	COG0799@1|root,COG0799@2|Bacteria,1MZEF@1224|Proteobacteria,42VN5@68525|delta/epsilon subdivisions,2WRGG@28221|Deltaproteobacteria,2YVQW@29|Myxococcales	28221|Deltaproteobacteria	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
SHD3_k127_4363946_16	448385.sce3674	1.206e-37	149.0	COG1576@1|root,COG1576@2|Bacteria,1R9Z2@1224|Proteobacteria,42S60@68525|delta/epsilon subdivisions,2WRAR@28221|Deltaproteobacteria,2Z3BB@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
SHD3_k127_436974_0	1254432.SCE1572_24215	3.585e-200	635.0	COG3507@1|root,COG3507@2|Bacteria,1NBF0@1224|Proteobacteria,4352Q@68525|delta/epsilon subdivisions,2WZDS@28221|Deltaproteobacteria,2Z1WZ@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43,RicinB_lectin_2
SHD3_k127_436974_1	867845.KI911784_gene654	2.949e-69	256.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_436974_2	1254432.SCE1572_18580	3.096e-54	197.0	COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,43E39@68525|delta/epsilon subdivisions,2X970@28221|Deltaproteobacteria,2Z2AF@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SHD3_k127_436974_4	373994.Riv7116_1428	6.254e-06	59.0	2DBMC@1|root,2Z9YC@2|Bacteria,1G29C@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_437008_0	525904.Tter_0313	4.19e-136	439.0	COG0137@1|root,COG0137@2|Bacteria,2NR2I@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	-	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SHD3_k127_437008_1	479434.Sthe_0205	4.189e-134	443.0	COG0165@1|root,COG0165@2|Bacteria,2G616@200795|Chloroflexi,27XG0@189775|Thermomicrobia	200795|Chloroflexi	E	argininosuccinate lyase	-	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Lyase_1
SHD3_k127_437008_2	557599.MKAN_03180	1.421e-55	207.0	COG4826@1|root,COG4826@2|Bacteria,2GJ5T@201174|Actinobacteria,23DWN@1762|Mycobacteriaceae	201174|Actinobacteria	O	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SHD3_k127_4383790_0	1254432.SCE1572_36375	1.193e-139	461.0	COG2433@1|root,COG2433@2|Bacteria,1RJ1Q@1224|Proteobacteria,43CJE@68525|delta/epsilon subdivisions,2X7TT@28221|Deltaproteobacteria,2Z3N4@29|Myxococcales	28221|Deltaproteobacteria	S	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66
SHD3_k127_4383790_1	1254432.SCE1572_46330	2.734e-20	94.0	COG3436@1|root,COG3436@2|Bacteria,1MZFT@1224|Proteobacteria	1224|Proteobacteria	L	IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
SHD3_k127_4383790_2	596151.DesfrDRAFT_4158	4.129e-05	50.0	COG2963@1|root,COG2963@2|Bacteria,1NGD6@1224|Proteobacteria,42X6G@68525|delta/epsilon subdivisions,2WT2N@28221|Deltaproteobacteria,2ME0K@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	IMG reference gene	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
SHD3_k127_4384581_1	765914.ThisiDRAFT_1228	3.242e-47	193.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RPWV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CZB,HAMP,MCPsignal
SHD3_k127_4384581_4	652103.Rpdx1_4951	1.363e-05	56.0	COG0745@1|root,COG0745@2|Bacteria,1N0YI@1224|Proteobacteria,2VEXA@28211|Alphaproteobacteria,3JWUY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07666	ko02020,ko02024,map02020,map02024	M00453	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_4384581_2	1121933.AUHH01000015_gene439	1.286e-46	177.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	GO:0008150,GO:0040007	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1606	PRA-CH
SHD3_k127_4384581_0	756272.Plabr_1918	2.579e-111	366.0	COG0040@1|root,COG0040@2|Bacteria,2IXEV@203682|Planctomycetes	203682|Planctomycetes	F	ATP phosphoribosyltransferase	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
SHD3_k127_4384581_3	391625.PPSIR1_33344	2.617e-23	104.0	COG1188@1|root,COG1188@2|Bacteria	2|Bacteria	J	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))	hslR	GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	5.4.99.23,5.4.99.24	ko:K04762,ko:K06179,ko:K06180	-	-	-	-	ko00000,ko01000,ko03009,ko03110	-	-	-	S4
SHD3_k127_4389805_3	448385.sce9052	8.029e-124	407.0	COG0323@1|root,COG0323@2|Bacteria,1MV61@1224|Proteobacteria,42MFX@68525|delta/epsilon subdivisions,2WJ91@28221|Deltaproteobacteria,2YU35@29|Myxococcales	28221|Deltaproteobacteria	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
SHD3_k127_4389805_1	1192034.CAP_5222	1.012e-142	472.0	COG0642@1|root,COG2205@2|Bacteria,1P4WV@1224|Proteobacteria,43ARK@68525|delta/epsilon subdivisions,2X65I@28221|Deltaproteobacteria,2YWWX@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SHD3_k127_4389805_5	1254432.SCE1572_03605	6.166e-31	132.0	COG2203@1|root,COG2203@2|Bacteria	2|Bacteria	T	Gaf domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS_4,PAS_8
SHD3_k127_4389805_0	448385.sce0512	1.241e-182	596.0	COG1287@1|root,COG1287@2|Bacteria	2|Bacteria	S	oligosaccharyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4389805_4	1192034.CAP_5226	3.692e-53	190.0	COG0776@1|root,COG0776@2|Bacteria,1MZ7M@1224|Proteobacteria,42TVD@68525|delta/epsilon subdivisions,2WQPX@28221|Deltaproteobacteria,2Z13W@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the bacterial histone-like protein family	ihfB	-	-	ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
SHD3_k127_439509_1	880072.Desac_1035	1.45e-140	458.0	COG0067@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0070@2|Bacteria,1NZ4D@1224|Proteobacteria,43B3T@68525|delta/epsilon subdivisions,2X6HR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	GXGXG motif	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GXGXG
SHD3_k127_439509_5	429009.Adeg_1335	3.328e-37	148.0	COG1150@1|root,COG1150@2|Bacteria,1V8UM@1239|Firmicutes,24J4U@186801|Clostridia,42GMS@68295|Thermoanaerobacterales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03390	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4_17,Fer4_8,Fer4_9
SHD3_k127_439509_2	243231.GSU0091	1.094e-83	287.0	COG2048@1|root,COG2048@2|Bacteria,1N37J@1224|Proteobacteria,42P51@68525|delta/epsilon subdivisions,2WK1J@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	heterodisulfide reductase	hdrB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
SHD3_k127_439509_0	1121472.AQWN01000006_gene1831	0.0	1403.0	COG0493@1|root,COG1148@1|root,COG0493@2|Bacteria,COG1148@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,26166@186807|Peptococcaceae	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Fer4_7,NAD_binding_8,Pyr_redox_2
SHD3_k127_439509_4	880072.Desac_0821	5.174e-41	175.0	COG1908@1|root,COG1908@2|Bacteria	2|Bacteria	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
SHD3_k127_439509_3	1232437.KL661971_gene4880	4.315e-52	189.0	COG4656@1|root,COG4656@2|Bacteria,1MWAX@1224|Proteobacteria,42NJM@68525|delta/epsilon subdivisions,2WJJB@28221|Deltaproteobacteria,2MHNS@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Methylene-tetrahydrofolate reductase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	MTHFR_C
SHD3_k127_4395744_4	756067.MicvaDRAFT_3375	6.093e-06	48.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,VCBS
SHD3_k127_4395744_0	192952.MM_1967	1.684e-63	230.0	COG3359@1|root,arCOG03130@2157|Archaea,2XUES@28890|Euryarchaeota,2NANN@224756|Methanomicrobia	224756|Methanomicrobia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
SHD3_k127_4395744_5	1410653.JHVC01000015_gene659	8.344e-05	54.0	COG2972@1|root,COG4936@1|root,COG2972@2|Bacteria,COG4936@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,36EDH@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,PocR
SHD3_k127_4395744_1	381666.H16_A0106	3.222e-41	156.0	COG0346@1|root,COG0346@2|Bacteria,1RH79@1224|Proteobacteria,2VRYP@28216|Betaproteobacteria,1KFN5@119060|Burkholderiaceae	28216|Betaproteobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SHD3_k127_4395744_2	448385.sce9187	7.812e-09	67.0	COG1633@1|root,COG1633@2|Bacteria,1Q2YM@1224|Proteobacteria,438N5@68525|delta/epsilon subdivisions,2X3W7@28221|Deltaproteobacteria,2YXBD@29|Myxococcales	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	-
SHD3_k127_4395744_6	7213.XP_004521881.1	0.0001312	54.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera	33208|Metazoa	T	Calcium ion binding	dp	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA
SHD3_k127_4395744_3	215803.DB30_7610	8.123e-08	64.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SHD3_k127_4401574_1	1192034.CAP_1142	2.204e-51	197.0	COG4305@1|root,COG4305@2|Bacteria,1MYW4@1224|Proteobacteria,434JK@68525|delta/epsilon subdivisions,2WYWV@28221|Deltaproteobacteria,2Z0TT@29|Myxococcales	28221|Deltaproteobacteria	G	Rare lipoprotein A (RlpA)-like double-psi beta-barrel	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	DPBB_1,Pollen_allerg_1
SHD3_k127_4401574_0	448385.sce7079	9.789e-245	779.0	COG4886@1|root,COG4886@2|Bacteria,1P5D8@1224|Proteobacteria,433SH@68525|delta/epsilon subdivisions,2WXRP@28221|Deltaproteobacteria,2Z2SK@29|Myxococcales	28221|Deltaproteobacteria	S	DUF3160	-	-	-	-	-	-	-	-	-	-	-	-	DUF3160
SHD3_k127_4406095_1	1211114.ALIP01000124_gene681	6.171e-28	117.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,1RNJP@1236|Gammaproteobacteria,1X5C6@135614|Xanthomonadales	135614|Xanthomonadales	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SHD3_k127_4406095_3	398579.Spea_3868	0.0003097	51.0	COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1R8DG@1224|Proteobacteria,1RP3K@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	OMP_b-brl,OmpA,TSP_3
SHD3_k127_4406095_2	550540.Fbal_1100	0.0001208	53.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	-	-	-	-	-	-	-	-	-	MtrB_PioB,OMP_b-brl,OmpA_membrane
SHD3_k127_4406095_0	243233.MCA2573	2.52e-250	783.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1MU31@1224|Proteobacteria,1RNBG@1236|Gammaproteobacteria,1XEFJ@135618|Methylococcales	135618|Methylococcales	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
SHD3_k127_4407647_1	1254432.SCE1572_20165	1.187e-76	268.0	COG2273@1|root,COG2273@2|Bacteria,1RANY@1224|Proteobacteria,437CZ@68525|delta/epsilon subdivisions,2X2IX@28221|Deltaproteobacteria,2Z2SU@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SHD3_k127_4407647_2	1291050.JAGE01000002_gene3871	6.875e-65	241.0	COG1621@1|root,COG3507@1|root,COG1621@2|Bacteria,COG3507@2|Bacteria,1VT6W@1239|Firmicutes,248X6@186801|Clostridia,3WNZ9@541000|Ruminococcaceae	186801|Clostridia	G	Cellulose Binding Domain Type IV	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1
SHD3_k127_4407647_0	909663.KI867150_gene1826	4.78e-196	625.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42N0C@68525|delta/epsilon subdivisions,2WJQQ@28221|Deltaproteobacteria,2MQT7@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	PFAM Aldehyde dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
SHD3_k127_4407647_3	59374.Fisuc_0389	3.621e-48	179.0	COG3507@1|root,COG5297@1|root,COG3507@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.8	ko:K01181,ko:K09955	-	-	-	-	ko00000,ko01000	-	-	-	ArabFuran-catal,CBM_4_9,CBM_6,DUF1080,DUF4091,Dockerin_1,F5_F8_type_C,Glyco_hydro_10,Glyco_hydro_127,Glyco_hydro_43,Laminin_G_3,RicinB_lectin_2
SHD3_k127_4412803_2	219305.MCAG_03935	6.58e-63	229.0	COG5184@1|root,COG5184@2|Bacteria,2IG31@201174|Actinobacteria,4DA30@85008|Micromonosporales	201174|Actinobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing proteins	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,CW_binding_2,RCC1,RCC1_2
SHD3_k127_4412803_3	1246448.ANAZ01000003_gene5408	1.417e-11	72.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4EK02@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_4412803_4	1439940.BAY1663_03402	6.961e-07	61.0	COG3712@1|root,COG3712@2|Bacteria,1MZCK@1224|Proteobacteria	1224|Proteobacteria	PT	Fe2 -dicitrate sensor, membrane component	fecR	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
SHD3_k127_4412803_0	927658.AJUM01000007_gene2723	9.275e-117	393.0	COG5520@1|root,COG5520@2|Bacteria,4PIPI@976|Bacteroidetes,2G1E7@200643|Bacteroidia,3XKYS@558415|Marinilabiliaceae	976|Bacteroidetes	M	Belongs to the glycosyl hydrolase 30 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4412803_1	290397.Adeh_3062	4.726e-113	399.0	COG4262@1|root,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_4416118_0	448385.sce8269	2.538e-198	625.0	COG0173@1|root,COG0173@2|Bacteria,1MUXB@1224|Proteobacteria,42NC6@68525|delta/epsilon subdivisions,2WJEV@28221|Deltaproteobacteria,2YTWY@29|Myxococcales	28221|Deltaproteobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
SHD3_k127_4416118_2	1254432.SCE1572_34090	4.582e-75	276.0	COG1506@1|root,COG1506@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PA14
SHD3_k127_4416118_1	903818.KI912268_gene1425	7.209e-89	320.0	COG4191@1|root,COG4191@2|Bacteria,3Y2IQ@57723|Acidobacteria	57723|Acidobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_9,Response_reg
SHD3_k127_4416118_7	1254432.SCE1572_30460	0.0004139	54.0	COG3568@1|root,COG3568@2|Bacteria,1PG5A@1224|Proteobacteria,43E4I@68525|delta/epsilon subdivisions,2WZPU@28221|Deltaproteobacteria,2Z2HE@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4416118_5	1125971.ASJB01000064_gene6524	0.000181	55.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4DZGM@85010|Pseudonocardiales	201174|Actinobacteria	Q	Poly(3-hydroxybutyrate) depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_4416118_3	1131812.JQMS01000001_gene985	2.955e-05	56.0	COG3210@1|root,COG3210@2|Bacteria,4NTNN@976|Bacteroidetes,1I414@117743|Flavobacteriia,2NX6N@237|Flavobacterium	976|Bacteroidetes	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,LTD
SHD3_k127_4416118_4	1321778.HMPREF1982_00776	0.0001579	50.0	2ATW4@1|root,31JFC@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4429431_1	1150864.MILUP08_41902	3.254e-73	278.0	COG4733@1|root,COG4733@2|Bacteria,2I9G5@201174|Actinobacteria,4DHDN@85008|Micromonosporales	201174|Actinobacteria	S	Glycoside hydrolase family 44	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_44,fn3
SHD3_k127_4429431_0	1408473.JHXO01000008_gene2711	5.168e-131	426.0	COG1472@1|root,COG1472@2|Bacteria,4NEBU@976|Bacteroidetes,2FN0J@200643|Bacteroidia	976|Bacteroidetes	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_4437506_1	525904.Tter_1945	3.87e-42	168.0	COG2207@1|root,COG2207@2|Bacteria,2NS0W@2323|unclassified Bacteria	2|Bacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K21826	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
SHD3_k127_4437506_4	1254432.SCE1572_13750	1.591e-26	121.0	COG0392@1|root,COG0392@2|Bacteria,1QDIG@1224|Proteobacteria,434TJ@68525|delta/epsilon subdivisions,2WZ4H@28221|Deltaproteobacteria,2Z1B9@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
SHD3_k127_4437506_0	1499967.BAYZ01000076_gene841	1.16e-96	330.0	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
SHD3_k127_4437506_2	448385.sce9040	1.183e-36	150.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria,2YU4W@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SHD3_k127_4475780_0	1123368.AUIS01000028_gene1324	4.125e-116	381.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	hydrolase family 65, central catalytic	ycjT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.64,3.2.1.28,5.4.2.6	ko:K01194,ko:K01838,ko:K04844,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
SHD3_k127_4475780_3	1123368.AUIS01000028_gene1323	4.666e-40	160.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
SHD3_k127_4475780_4	448385.sce7729	4.942e-29	117.0	COG0667@1|root,COG0667@2|Bacteria,1R77F@1224|Proteobacteria,42Y4Z@68525|delta/epsilon subdivisions,2WTTZ@28221|Deltaproteobacteria,2YYIM@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SHD3_k127_4475780_5	204669.Acid345_4508	5.22e-09	61.0	COG1453@1|root,COG1453@2|Bacteria,3Y99H@57723|Acidobacteria,2JP09@204432|Acidobacteriia	204432|Acidobacteriia	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SHD3_k127_4475780_1	118166.JH976538_gene5057	3.208e-114	394.0	COG4191@1|root,COG4191@2|Bacteria,1G1PE@1117|Cyanobacteria,1H8US@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_4,PAS_8,Response_reg
SHD3_k127_4475780_2	1192034.CAP_1015	4.828e-92	314.0	COG2273@1|root,COG3179@1|root,COG2273@2|Bacteria,COG3179@2|Bacteria,1NFHX@1224|Proteobacteria,43AJK@68525|delta/epsilon subdivisions,2X5ZT@28221|Deltaproteobacteria,2YUVB@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SHD3_k127_4476524_7	1254432.SCE1572_45825	6.486e-21	95.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF4234,FHA,zinc_ribbon_2
SHD3_k127_4476524_2	448385.sce7983	4.27e-130	435.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	2.4.1.227,2.7.11.1,3.4.11.2	ko:K01256,ko:K02563,ko:K08776,ko:K12132	ko00480,ko00550,ko01100,ko01502,ko04112,map00480,map00550,map01100,map01502,map04112	-	R00899,R04951,R05032,R05662	RC00005,RC00049,RC00096,RC00141	ko00000,ko00001,ko01000,ko01001,ko01002,ko01011	-	GT28	-	HEAT_2,Peptidase_M1,Sulfatase,T2SSE_N
SHD3_k127_4476524_0	1192034.CAP_1783	6.713e-253	806.0	COG1674@1|root,COG1674@2|Bacteria,1MVPI@1224|Proteobacteria,42N4X@68525|delta/epsilon subdivisions,2WIPR@28221|Deltaproteobacteria,2YU2E@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the FtsK SpoIIIE SftA family	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
SHD3_k127_4476524_4	1254432.SCE1572_45845	1.11e-80	277.0	2ETUP@1|root,33MBY@2|Bacteria,1NG8K@1224|Proteobacteria,42XR1@68525|delta/epsilon subdivisions,2WSS8@28221|Deltaproteobacteria,2YW5Y@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4476524_6	1479238.JQMZ01000001_gene936	1.247e-29	130.0	COG0774@1|root,COG0774@2|Bacteria,1MV6T@1224|Proteobacteria,2TUHH@28211|Alphaproteobacteria,43X28@69657|Hyphomonadaceae	28211|Alphaproteobacteria	M	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	lpxC	-	3.5.1.108	ko:K02535	ko00540,ko01100,map00540,map01100	M00060	R04587	RC00166,RC00300	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxC
SHD3_k127_4476524_3	1254432.SCE1572_45855	5.406e-105	351.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YV9N@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
SHD3_k127_4476524_1	448385.sce7919	5.055e-150	484.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce7919|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4480791_6	1122247.C731_4532	2.068e-35	139.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,2GNII@201174|Actinobacteria,23687@1762|Mycobacteriaceae	201174|Actinobacteria	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
SHD3_k127_4480791_4	1192034.CAP_1439	2.604e-53	198.0	COG4886@1|root,COG4886@2|Bacteria,1R9FD@1224|Proteobacteria,435HC@68525|delta/epsilon subdivisions,2X99T@28221|Deltaproteobacteria,2Z2T4@29|Myxococcales	28221|Deltaproteobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4480791_3	313596.RB2501_08035	5.756e-83	295.0	COG0304@1|root,COG0304@2|Bacteria,4NGJD@976|Bacteroidetes,1HYKN@117743|Flavobacteriia	976|Bacteroidetes	IQ	Belongs to the beta-ketoacyl-ACP synthases family	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SHD3_k127_4480791_7	187272.Mlg_1738	1.188e-08	64.0	COG0704@1|root,COG0704@2|Bacteria,1NRGK@1224|Proteobacteria,1SMQP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	PhoU domain	-	-	-	-	-	-	-	-	-	-	-	-	PhoU
SHD3_k127_4480791_1	686340.Metal_2212	4.913e-130	432.0	COG1858@1|root,COG1858@2|Bacteria,1MV70@1224|Proteobacteria,1RPPQ@1236|Gammaproteobacteria,1XG6A@135618|Methylococcales	135618|Methylococcales	C	Di-haem cytochrome c peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG,Haem_bd
SHD3_k127_4480791_0	1501391.LG35_06985	3.153e-133	442.0	COG2509@1|root,COG2509@2|Bacteria,4NEUQ@976|Bacteroidetes,2FM1G@200643|Bacteroidia,22U7Z@171550|Rikenellaceae	976|Bacteroidetes	S	FAD binding domain	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,FAD_binding_3,GIDA,HI0933_like,Pyr_redox_2
SHD3_k127_4480791_2	1192034.CAP_0080	3.296e-122	404.0	COG1262@1|root,COG1262@2|Bacteria,1R59H@1224|Proteobacteria	1224|Proteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_4480791_5	945713.IALB_3030	1.509e-35	140.0	COG3439@1|root,COG3439@2|Bacteria	2|Bacteria	D	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
SHD3_k127_4489870_0	710111.FraQA3DRAFT_0729	5.363e-96	360.0	COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4EW27@85013|Frankiales	201174|Actinobacteria	M	TIGRFAM YD repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	SpvB,TcdB_toxin_midC,TcdB_toxin_midN,VCBS
SHD3_k127_4489870_1	485913.Krac_9959	2.168e-29	136.0	COG2730@1|root,COG5297@1|root,COG2730@2|Bacteria,COG5297@2|Bacteria,2G8G7@200795|Chloroflexi	200795|Chloroflexi	G	PFAM glycoside hydrolase family 5	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_3,Cellulase
SHD3_k127_4490153_0	448385.sce1616	0.0	1106.0	COG0457@1|root,COG0457@2|Bacteria,1PEH7@1224|Proteobacteria,42TVC@68525|delta/epsilon subdivisions,2WSCX@28221|Deltaproteobacteria,2YXM3@29|Myxococcales	28221|Deltaproteobacteria	O	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,TPR_14,TPR_16,TPR_2,TPR_4,TPR_6,TPR_8
SHD3_k127_4490153_5	1123070.KB899247_gene1428	4.017e-08	65.0	COG3391@1|root,COG3712@1|root,COG3391@2|Bacteria,COG3712@2|Bacteria,46UNY@74201|Verrucomicrobia,2IVKN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,FecR,PA14
SHD3_k127_4490153_6	561175.KB894093_gene3113	4.652e-05	55.0	COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4EJ4G@85012|Streptosporangiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
SHD3_k127_4490153_3	1192034.CAP_7446	1.53e-91	314.0	COG0392@1|root,COG0392@2|Bacteria,1PPSZ@1224|Proteobacteria,434R6@68525|delta/epsilon subdivisions,2WZ2B@28221|Deltaproteobacteria,2Z16A@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SHD3_k127_4490153_1	1192034.CAP_7446	7.362e-98	332.0	COG0392@1|root,COG0392@2|Bacteria,1PPSZ@1224|Proteobacteria,434R6@68525|delta/epsilon subdivisions,2WZ2B@28221|Deltaproteobacteria,2Z16A@29|Myxococcales	28221|Deltaproteobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
SHD3_k127_4490153_2	1340493.JNIF01000004_gene385	1.989e-92	312.0	COG0388@1|root,COG0388@2|Bacteria,3Y2T9@57723|Acidobacteria	57723|Acidobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SHD3_k127_4491065_2	448385.sce1745	1.403e-18	89.0	COG2331@1|root,COG2331@2|Bacteria,1N6Q9@1224|Proteobacteria,42V24@68525|delta/epsilon subdivisions,2WR87@28221|Deltaproteobacteria,2YW0Y@29|Myxococcales	28221|Deltaproteobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
SHD3_k127_4491065_0	448385.sce1744	0.0	1142.0	COG1196@1|root,COG1196@2|Bacteria,1MUAQ@1224|Proteobacteria,42MN9@68525|delta/epsilon subdivisions,2WJZF@28221|Deltaproteobacteria,2YU45@29|Myxococcales	28221|Deltaproteobacteria	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
SHD3_k127_4491065_1	547042.BACCOPRO_00455	2.611e-64	240.0	COG0251@1|root,COG0251@2|Bacteria,4NEVA@976|Bacteroidetes,2FN38@200643|Bacteroidia,4AKJZ@815|Bacteroidaceae	976|Bacteroidetes	J	endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
SHD3_k127_4491983_3	377629.TERTU_0094	1.104e-30	126.0	COG0627@1|root,COG0627@2|Bacteria,1QR76@1224|Proteobacteria,1RU21@1236|Gammaproteobacteria,2PQC4@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SHD3_k127_4491983_2	448385.sce0315	1.035e-30	135.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2,YjbH
SHD3_k127_4491983_0	448385.sce6675	4.077e-60	227.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce6675|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4491983_4	751945.Theos_0271	1.011e-16	94.0	COG1470@1|root,COG3895@1|root,COG1470@2|Bacteria,COG3895@2|Bacteria,1WIA5@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	PFAM PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,PEGA
SHD3_k127_4491983_1	246197.MXAN_0518	2.37e-32	138.0	COG0457@1|root,COG1629@1|root,COG0457@2|Bacteria,COG4771@2|Bacteria,1MUC1@1224|Proteobacteria,42R8H@68525|delta/epsilon subdivisions,2WMWF@28221|Deltaproteobacteria,2Z0PV@29|Myxococcales	28221|Deltaproteobacteria	M	TonB-dependent Receptor Plug Domain	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	PEGA,Plug,TonB_dep_Rec
SHD3_k127_4508812_7	1192034.CAP_0345	9.198e-27	112.0	COG0848@1|root,COG0848@2|Bacteria,1RENY@1224|Proteobacteria,42X3K@68525|delta/epsilon subdivisions,2WT0T@28221|Deltaproteobacteria,2YW1G@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	aglS	-	-	-	-	-	-	-	-	-	-	-	ExbD
SHD3_k127_4508812_5	1192034.CAP_0344	1.53e-55	199.0	COG0848@1|root,COG0848@2|Bacteria,1N8FU@1224|Proteobacteria,42WU3@68525|delta/epsilon subdivisions,2WSMD@28221|Deltaproteobacteria,2YZRG@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
SHD3_k127_4508812_2	1192034.CAP_0343	6.385e-97	322.0	COG0811@1|root,COG0811@2|Bacteria,1PKF8@1224|Proteobacteria,43BH3@68525|delta/epsilon subdivisions,2X6VD@28221|Deltaproteobacteria,2YV1A@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	aglR2	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
SHD3_k127_4508812_1	448385.sce2993	7.479e-99	327.0	COG0811@1|root,COG0811@2|Bacteria,1MX5J@1224|Proteobacteria,42NWR@68525|delta/epsilon subdivisions,2WK2E@28221|Deltaproteobacteria,2YVC0@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	DUF3450,MotA_ExbB
SHD3_k127_4508812_4	448385.sce2992	2.664e-56	201.0	COG0848@1|root,COG0848@2|Bacteria,1N8FU@1224|Proteobacteria,42WU3@68525|delta/epsilon subdivisions,2WSMD@28221|Deltaproteobacteria,2YW1Y@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
SHD3_k127_4508812_3	1192034.CAP_0340	6.618e-69	239.0	COG0848@1|root,COG0848@2|Bacteria,1NA7P@1224|Proteobacteria,42V1Q@68525|delta/epsilon subdivisions,2WSGW@28221|Deltaproteobacteria,2YY8R@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	-	-	-	-	-	-	-	-	-	ExbD
SHD3_k127_4508812_6	1519464.HY22_06785	2.497e-52	210.0	COG3808@1|root,COG3808@2|Bacteria,1FD6P@1090|Chlorobi	1090|Chlorobi	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SHD3_k127_4508812_0	215803.DB30_4326	2.139e-188	633.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,42M5P@68525|delta/epsilon subdivisions,2WIW8@28221|Deltaproteobacteria,2YU7C@29|Myxococcales	28221|Deltaproteobacteria	KL	helicase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
SHD3_k127_4514122_5	1121918.ARWE01000001_gene2997	1.888e-14	76.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,43UHD@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	ATP-grasp domain	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SHD3_k127_4514122_2	96561.Dole_2566	2.703e-117	391.0	COG1032@1|root,COG1032@2|Bacteria,1MUMS@1224|Proteobacteria,42QFG@68525|delta/epsilon subdivisions,2WK91@28221|Deltaproteobacteria,2MK0R@213118|Desulfobacterales	28221|Deltaproteobacteria	C	PFAM Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_4514122_1	448385.sce8063	1.909e-122	404.0	COG3876@1|root,COG3876@2|Bacteria,1MX3S@1224|Proteobacteria,42N6K@68525|delta/epsilon subdivisions,2WKFH@28221|Deltaproteobacteria,2YUIN@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF1343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1343
SHD3_k127_4514122_0	1254432.SCE1572_17585	2.994e-230	726.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YTY9@29|Myxococcales	28221|Deltaproteobacteria	T	response regulator	-	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_4514122_3	1192034.CAP_8363	5.41e-94	330.0	COG0515@1|root,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439KJ@68525|delta/epsilon subdivisions,2X4XC@28221|Deltaproteobacteria,2Z096@29|Myxococcales	28221|Deltaproteobacteria	KLT	Lipopolysaccharide kinase (Kdo/WaaP) family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4514122_4	1254432.SCE1572_03760	2.42e-45	169.0	2EE3P@1|root,337Y9@2|Bacteria	2|Bacteria	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
SHD3_k127_4517650_3	290397.Adeh_3529	1.884e-121	434.0	COG0642@1|root,COG0784@1|root,COG2461@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,43CCU@68525|delta/epsilon subdivisions,2X7NQ@28221|Deltaproteobacteria,2YX99@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_4517650_1	1254432.SCE1572_03445	9.052e-160	520.0	COG3866@1|root,COG3866@2|Bacteria	2|Bacteria	G	Pectate lyase	-	-	3.2.1.202,4.2.2.2	ko:K01728,ko:K21606	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	CBM5,GH18	-	Beta_helix,Big_5,CBM_2,CBM_5_12_2,CBM_6,ChiC,Glyco_hydro_18,Lipase_GDSL_2,Pec_lyase_C,Pectinesterase
SHD3_k127_4517650_0	1254432.SCE1572_06575	3.952e-180	582.0	COG5520@1|root,COG5520@2|Bacteria,1NNIB@1224|Proteobacteria,43432@68525|delta/epsilon subdivisions,2X4ZB@28221|Deltaproteobacteria,2YZVW@29|Myxococcales	28221|Deltaproteobacteria	M	O-Glycosyl hydrolase family 30	-	-	3.2.1.164	ko:K18579	-	-	-	-	ko00000,ko01000	-	GH5	-	Glyco_hydr_30_2
SHD3_k127_4517650_5	1254432.SCE1572_00620	0.0002626	45.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_4517650_4	885580.XP_010603918.1	7.998e-16	85.0	KOG4297@1|root,KOG4297@2759|Eukaryota,39X2I@33154|Opisthokonta,3BNNA@33208|Metazoa,3D0U7@33213|Bilateria,485EY@7711|Chordata,4988M@7742|Vertebrata,3JE70@40674|Mammalia,35CE0@314146|Euarchontoglires,4PTN5@9989|Rodentia	33208|Metazoa	T	Low affinity immunoglobulin epsilon Fc	FCER2	GO:0002682,GO:0002684,GO:0002697,GO:0002699,GO:0002703,GO:0002705,GO:0002706,GO:0002708,GO:0002712,GO:0002714,GO:0002819,GO:0002821,GO:0002822,GO:0002824,GO:0002889,GO:0002891,GO:0002920,GO:0002922,GO:0002923,GO:0002925,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0007154,GO:0007165,GO:0007166,GO:0007219,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0010556,GO:0010557,GO:0010604,GO:0016020,GO:0016021,GO:0019221,GO:0019222,GO:0023052,GO:0031224,GO:0031226,GO:0031341,GO:0031343,GO:0032768,GO:0032770,GO:0034097,GO:0042221,GO:0043085,GO:0043900,GO:0043902,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0044877,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050794,GO:0050839,GO:0050896,GO:0050999,GO:0051000,GO:0051341,GO:0051353,GO:0051709,GO:0051712,GO:0051716,GO:0051769,GO:0051770,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071310,GO:0071345,GO:0071944,GO:0098552	-	ko:K06468	ko04640,ko05169,map04640,map05169	-	-	-	ko00000,ko00001,ko04090,ko04091	-	-	-	Lectin_C
SHD3_k127_4517650_2	153721.MYP_4345	3.738e-133	441.0	COG1506@1|root,COG1506@2|Bacteria,4PKQ3@976|Bacteroidetes,47XYQ@768503|Cytophagia	976|Bacteroidetes	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	CBM9_1,Peptidase_S9
SHD3_k127_451930_0	1192034.CAP_4027	9.052e-253	815.0	COG0642@1|root,COG1352@1|root,COG5002@1|root,COG1352@2|Bacteria,COG2205@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF_2,HATPase_c,HisKA,PAS,PAS_10,PAS_4,PAS_9,Response_reg
SHD3_k127_451930_2	1254432.SCE1572_28130	3.615e-89	306.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	CBM_2,Esterase_phd,Peptidase_S9,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_451930_1	913865.DOT_2771	8.081e-97	331.0	COG0346@1|root,COG3315@1|root,COG0346@2|Bacteria,COG3315@2|Bacteria,1V5T8@1239|Firmicutes	1239|Firmicutes	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
SHD3_k127_4519378_6	575540.Isop_0572	7.957e-13	69.0	COG0388@1|root,COG0388@2|Bacteria,2IX91@203682|Planctomycetes	203682|Planctomycetes	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
SHD3_k127_4519378_3	1267535.KB906767_gene5095	1.706e-104	351.0	COG2957@1|root,COG2957@2|Bacteria,3Y2W5@57723|Acidobacteria,2JIKF@204432|Acidobacteriia	204432|Acidobacteriia	E	Belongs to the agmatine deiminase family	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
SHD3_k127_4519378_7	376733.IT41_03810	8.028e-06	59.0	COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,1QV29@1224|Proteobacteria,2TW8Q@28211|Alphaproteobacteria,2PVI4@265|Paracoccus	28211|Alphaproteobacteria	M	Lysin motif	lysM	-	-	-	-	-	-	-	-	-	-	-	LysM,Peptidase_M23
SHD3_k127_4519378_0	404589.Anae109_2216	4.227e-148	480.0	COG1157@1|root,COG1157@2|Bacteria,1MUH6@1224|Proteobacteria,42M0K@68525|delta/epsilon subdivisions,2WISR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	PFAM H transporting two-sector ATPase alpha beta subunit central region	fliI	-	3.6.3.14	ko:K02412,ko:K03224	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko01000,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	ATP-synt_ab,ATP-synt_ab_N
SHD3_k127_4519378_1	1192034.CAP_7152	2.487e-124	407.0	COG0484@1|root,COG0484@2|Bacteria,1MVMS@1224|Proteobacteria,42KZM@68525|delta/epsilon subdivisions,2WJGP@28221|Deltaproteobacteria,2YXG3@29|Myxococcales	28221|Deltaproteobacteria	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
SHD3_k127_4519378_4	448385.sce7189	2.79e-51	199.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
SHD3_k127_4526036_3	436229.JOEH01000006_gene2713	3.362e-18	89.0	COG1846@1|root,COG1846@2|Bacteria,2IM7W@201174|Actinobacteria,2NIXG@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SHD3_k127_4526036_2	448385.sce3153	4.93e-92	308.0	COG0670@1|root,COG0670@2|Bacteria,1R7VN@1224|Proteobacteria,43DVQ@68525|delta/epsilon subdivisions,2WZ04@28221|Deltaproteobacteria,2Z11K@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
SHD3_k127_4526036_0	1192034.CAP_0096	1.06e-160	524.0	COG0608@1|root,COG0608@2|Bacteria,1MU1M@1224|Proteobacteria,42MYF@68525|delta/epsilon subdivisions,2WJE3@28221|Deltaproteobacteria,2YTVE@29|Myxococcales	28221|Deltaproteobacteria	L	single-stranded-DNA-specific exonuclease RecJ	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
SHD3_k127_4526036_1	448385.sce4479	3.163e-111	364.0	COG1127@1|root,COG1127@2|Bacteria,1MUSD@1224|Proteobacteria,42NTG@68525|delta/epsilon subdivisions,2X5CT@28221|Deltaproteobacteria,2YV0W@29|Myxococcales	28221|Deltaproteobacteria	Q	ABC transporter	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
SHD3_k127_4526547_0	1254432.SCE1572_04890	7.053e-156	505.0	COG0477@1|root,COG2814@2|Bacteria,1QTX0@1224|Proteobacteria,42PT2@68525|delta/epsilon subdivisions,2WJ6Q@28221|Deltaproteobacteria,2YWF8@29|Myxococcales	28221|Deltaproteobacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
SHD3_k127_4526547_2	316067.Geob_2058	4.853e-72	254.0	COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria	1224|Proteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran
SHD3_k127_4526547_1	1192034.CAP_0509	1.948e-77	273.0	COG2755@1|root,COG2755@2|Bacteria,1R7BU@1224|Proteobacteria,43428@68525|delta/epsilon subdivisions,2X4SY@28221|Deltaproteobacteria,2YZIV@29|Myxococcales	28221|Deltaproteobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
SHD3_k127_4528163_2	1192034.CAP_6336	1.165e-61	220.0	COG0731@1|root,COG0731@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
SHD3_k127_4528163_6	1121920.AUAU01000002_gene2147	1.096e-08	68.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	ubiA	-	2.5.1.133,2.5.1.62	ko:K04040,ko:K20616	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06284,R09067,R11514,R11517	RC00020	ko00000,ko00001,ko01000,ko01006	-	-	-	UbiA
SHD3_k127_4528163_0	1254432.SCE1572_37135	5.149e-133	451.0	COG0457@1|root,COG0741@1|root,COG0457@2|Bacteria,COG0741@2|Bacteria,1MV3F@1224|Proteobacteria,42N7A@68525|delta/epsilon subdivisions,2WQFJ@28221|Deltaproteobacteria,2YV3N@29|Myxococcales	28221|Deltaproteobacteria	M	Transglycosylase SLT domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	SLT,SLT_L,TPR_16,TPR_6
SHD3_k127_4528163_1	1254432.SCE1572_49385	2.286e-108	361.0	COG3178@1|root,COG3178@2|Bacteria,1MXCH@1224|Proteobacteria,42TUJ@68525|delta/epsilon subdivisions,2WQ4U@28221|Deltaproteobacteria,2YX6A@29|Myxococcales	28221|Deltaproteobacteria	S	Choline/ethanolamine kinase	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
SHD3_k127_4528163_3	1192034.CAP_1560	1.106e-45	175.0	COG0357@1|root,COG0357@2|Bacteria	2|Bacteria	J	rRNA methyltransferase activity	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
SHD3_k127_4528163_5	1307759.JOMJ01000003_gene102	1.837e-19	100.0	2CGNA@1|root,3301B@2|Bacteria,1N74P@1224|Proteobacteria,42VID@68525|delta/epsilon subdivisions,2WRHN@28221|Deltaproteobacteria,2MD48@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4529051_9	391625.PPSIR1_05378	2.977e-61	221.0	COG3405@1|root,COG3405@2|Bacteria,1N41Q@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_8
SHD3_k127_4529051_5	1254432.SCE1572_23445	2.016e-86	294.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2YVGX@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SHD3_k127_4529051_15	1192034.CAP_6993	1.636e-17	88.0	COG1826@1|root,COG1826@2|Bacteria	2|Bacteria	U	protein secretion	tatB	GO:0003674,GO:0005215	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SHD3_k127_4529051_13	1283287.KB822578_gene2367	1.965e-28	128.0	COG2339@1|root,COG2339@2|Bacteria,2GKR5@201174|Actinobacteria,4DQ3Y@85009|Propionibacteriales	201174|Actinobacteria	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
SHD3_k127_4529051_6	1192034.CAP_4611	1.13e-69	245.0	COG0755@1|root,COG0755@2|Bacteria,1MU61@1224|Proteobacteria,42RU4@68525|delta/epsilon subdivisions,2WNN7@28221|Deltaproteobacteria,2YVGN@29|Myxococcales	28221|Deltaproteobacteria	O	Cytochrome C assembly protein	ccmC	-	-	ko:K02195	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.107	-	-	Cytochrom_C_asm
SHD3_k127_4529051_0	1254432.SCE1572_21860	8.157e-186	601.0	COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42Q0K@68525|delta/epsilon subdivisions,2WJUW@28221|Deltaproteobacteria,2YTVH@29|Myxococcales	28221|Deltaproteobacteria	L	DbpA RNA binding domain	dedA	-	3.6.4.13	ko:K03732,ko:K05592	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
SHD3_k127_4529051_8	1192034.CAP_8701	1.715e-62	230.0	COG0142@1|root,COG0142@2|Bacteria,1MUK6@1224|Proteobacteria,42M1B@68525|delta/epsilon subdivisions,2WK2M@28221|Deltaproteobacteria,2YVA6@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the FPP GGPP synthase family	ispB	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
SHD3_k127_4529051_2	1192034.CAP_7939	1.767e-118	397.0	COG0457@1|root,COG0457@2|Bacteria,1QX47@1224|Proteobacteria,42Y0X@68525|delta/epsilon subdivisions,2WT7V@28221|Deltaproteobacteria,2YW72@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,Zincin_1
SHD3_k127_4529051_1	448385.sce3607	7.661e-133	450.0	COG1376@1|root,COG1376@2|Bacteria,1NKBB@1224|Proteobacteria,432T9@68525|delta/epsilon subdivisions,2X2MM@28221|Deltaproteobacteria,2Z0G3@29|Myxococcales	28221|Deltaproteobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SHD3_k127_4529051_10	448385.sce0938	4.758e-48	178.0	COG0853@1|root,COG0853@2|Bacteria,1RI1B@1224|Proteobacteria,42SBM@68525|delta/epsilon subdivisions,2WQ24@28221|Deltaproteobacteria,2Z0M5@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
SHD3_k127_4529051_3	1254432.SCE1572_49075	7.804e-113	380.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_4529051_4	1254432.SCE1572_49080	3.562e-97	336.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria	1224|Proteobacteria	C	Belongs to the peptidase M16 family	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_4538305_5	1242864.D187_000320	7.592e-27	111.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YYYT@29|Myxococcales	28221|Deltaproteobacteria	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
SHD3_k127_4538305_0	265072.Mfla_1306	4.74e-238	772.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,2VKKR@28216|Betaproteobacteria,2KM5P@206350|Nitrosomonadales	206350|Nitrosomonadales	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K15726	-	-	-	-	ko00000,ko02000	2.A.6.1.2	-	-	ACR_tran
SHD3_k127_4538305_3	1242864.D187_000321	1.641e-58	219.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SHD3_k127_4538305_4	1242864.D187_000322	3.5e-43	177.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SHD3_k127_4538305_7	1254432.SCE1572_05205	2.277e-12	80.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like,EGF_CA,SLH
SHD3_k127_4538305_1	1192034.CAP_5270	4.921e-196	636.0	COG1629@1|root,COG4771@2|Bacteria,1QX4E@1224|Proteobacteria,437VM@68525|delta/epsilon subdivisions,2X358@28221|Deltaproteobacteria,2YUBU@29|Myxococcales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_C,TonB_dep_Rec
SHD3_k127_4538305_6	1242864.D187_005314	3.357e-22	113.0	COG3055@1|root,COG4447@1|root,COG3055@2|Bacteria,COG4447@2|Bacteria,1P49S@1224|Proteobacteria,4350R@68525|delta/epsilon subdivisions,2WZBJ@28221|Deltaproteobacteria,2Z1SD@29|Myxococcales	28221|Deltaproteobacteria	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4538305_2	641524.ADICYQ_0725	1.172e-59	235.0	COG1404@1|root,COG3291@1|root,COG1404@2|Bacteria,COG3291@2|Bacteria,4NFMW@976|Bacteroidetes,47X9G@768503|Cytophagia	976|Bacteroidetes	O	PFAM peptidase S8 and S53 subtilisin kexin sedolisin	-	-	-	-	-	-	-	-	-	-	-	-	PKD,P_proprotein,Peptidase_S8,fn3
SHD3_k127_4549112_3	36875.HQ29_01355	7.668e-09	58.0	COG0543@1|root,COG0543@2|Bacteria,4NJ0I@976|Bacteroidetes,2FNBW@200643|Bacteroidia,22WH8@171551|Porphyromonadaceae	976|Bacteroidetes	C	Ferredoxin-NADP reductase	gltD	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SHD3_k127_4549112_0	515635.Dtur_1752	2.406e-82	302.0	COG1609@1|root,COG2199@1|root,COG1609@2|Bacteria,COG2199@2|Bacteria	2|Bacteria	T	diguanylate cyclase activity	-	-	-	ko:K02103,ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	GAF,GGDEF,Peripla_BP_3
SHD3_k127_4549112_2	644282.Deba_2158	2.198e-40	167.0	COG4753@1|root,COG5002@1|root,COG4753@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42QJF@68525|delta/epsilon subdivisions,2WJ9D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
SHD3_k127_4549112_1	666685.R2APBS1_2352	5.293e-41	159.0	COG0350@1|root,COG0350@2|Bacteria,1N2YQ@1224|Proteobacteria,1S68H@1236|Gammaproteobacteria,1X6DF@135614|Xanthomonadales	135614|Xanthomonadales	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N
SHD3_k127_4557905_9	326424.FRAAL4481	1.93e-06	60.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_4557905_5	1192034.CAP_5639	1.513e-21	109.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	PEGA,TPR_16,TPR_6,TPR_8
SHD3_k127_4557905_2	448385.sce7925	2.274e-102	353.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce7925|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4557905_6	448385.sce8677	2.683e-11	67.0	COG0268@1|root,COG0268@2|Bacteria	2|Bacteria	J	rRNA binding	rpsT	GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
SHD3_k127_4557905_3	448385.sce8680	1.811e-82	278.0	COG1595@1|root,COG1595@2|Bacteria,1RKMN@1224|Proteobacteria,431Z5@68525|delta/epsilon subdivisions,2WWH8@28221|Deltaproteobacteria,2Z13Y@29|Myxococcales	28221|Deltaproteobacteria	K	RNA polymerase sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_4557905_0	1192034.CAP_2867	1.704e-152	500.0	COG0539@1|root,COG0539@2|Bacteria,1N2EJ@1224|Proteobacteria,42NXS@68525|delta/epsilon subdivisions,2WJ0A@28221|Deltaproteobacteria,2YV19@29|Myxococcales	28221|Deltaproteobacteria	J	Ribosomal protein S1-like RNA-binding domain	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
SHD3_k127_4557905_1	1254432.SCE1572_42150	1.088e-116	385.0	COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,42NR0@68525|delta/epsilon subdivisions,2WIPG@28221|Deltaproteobacteria,2YU3H@29|Myxococcales	28221|Deltaproteobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
SHD3_k127_4557905_4	448385.sce6970	6.428e-58	218.0	2ANEP@1|root,31GV0@2|Bacteria,1Q9YI@1224|Proteobacteria,434PP@68525|delta/epsilon subdivisions,2WZ0X@28221|Deltaproteobacteria,2Z134@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4557965_14	1254432.SCE1572_24255	1.654e-35	153.0	COG0642@1|root,COG3437@1|root,COG2205@2|Bacteria,COG3437@2|Bacteria,1P1A3@1224|Proteobacteria,42R7R@68525|delta/epsilon subdivisions,2WMT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HATPase_c,HisKA,PAS,Response_reg
SHD3_k127_4557965_16	1087481.AGFX01000037_gene4482	8.41e-24	116.0	COG4191@1|root,COG4191@2|Bacteria,1UJKY@1239|Firmicutes,4ITB2@91061|Bacilli,277B1@186822|Paenibacillaceae	91061|Bacilli	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4
SHD3_k127_4557965_2	448385.sce2668	4.764e-145	511.0	COG2203@1|root,COG3829@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HTH_8,Sigma54_activat
SHD3_k127_4557965_21	502025.Hoch_5749	1.934e-08	63.0	COG1262@1|root,COG1262@2|Bacteria,1R0NM@1224|Proteobacteria,43CZA@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4557965_24	378806.STAUR_3871	5.279e-05	54.0	2C9DJ@1|root,33GUH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	OMP_b-brl
SHD3_k127_4557965_7	448385.sce6893	1.037e-72	254.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_2,DLH
SHD3_k127_4557965_3	1254432.SCE1572_39075	9.15e-129	430.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_4557965_6	1242864.D187_004766	1.085e-78	269.0	COG0463@1|root,COG0463@2|Bacteria,1QW1R@1224|Proteobacteria,42R1R@68525|delta/epsilon subdivisions,2WMTK@28221|Deltaproteobacteria,2YUV3@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
SHD3_k127_4557965_5	1122604.JONR01000050_gene3144	6.214e-95	326.0	COG5000@1|root,COG5000@2|Bacteria,1MWKZ@1224|Proteobacteria,1RQ8B@1236|Gammaproteobacteria,1X41T@135614|Xanthomonadales	135614|Xanthomonadales	T	Histidine kinase	styS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_8
SHD3_k127_4557965_1	448385.sce8837	7.095e-170	546.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria,2YU6E@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_4557965_23	1123386.AUIW01000009_gene1813	4.006e-07	56.0	2DGZ3@1|root,2ZXUD@2|Bacteria,1WKRC@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
SHD3_k127_4557965_18	1123386.AUIW01000009_gene1812	2.045e-19	97.0	COG1848@1|root,COG1848@2|Bacteria,1WKJ4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4557965_22	1122176.KB903534_gene2171	2.224e-08	65.0	2EN4P@1|root,33FSQ@2|Bacteria,4NZ3C@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4557965_4	448385.sce4952	2.393e-103	353.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria,2YUVI@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4557965_11	448385.sce4951	1.421e-46	193.0	2ANDU@1|root,31DCF@2|Bacteria,1QAIC@1224|Proteobacteria,43541@68525|delta/epsilon subdivisions,2X956@28221|Deltaproteobacteria,2Z1ZX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VCBS
SHD3_k127_4557965_8	1192034.CAP_6502	2.272e-68	251.0	COG1470@1|root,COG1470@2|Bacteria,1Q9IM@1224|Proteobacteria,434EQ@68525|delta/epsilon subdivisions,2WYS3@28221|Deltaproteobacteria,2Z0GH@29|Myxococcales	28221|Deltaproteobacteria	S	PEGA domain	-	-	-	-	-	-	-	-	-	-	-	-	PEGA
SHD3_k127_4557965_0	448385.sce2511	1.447e-235	756.0	COG0810@1|root,COG1629@1|root,COG0810@2|Bacteria,COG4771@2|Bacteria,1R5B9@1224|Proteobacteria,43C1I@68525|delta/epsilon subdivisions,2X7C6@28221|Deltaproteobacteria,2YWPC@29|Myxococcales	28221|Deltaproteobacteria	MP	Periplasmic protein TonB links inner and outer membranes	-	-	-	-	-	-	-	-	-	-	-	-	CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_C,TonB_dep_Rec
SHD3_k127_4557965_17	448385.sce4317	9.9e-21	102.0	29R0Y@1|root,30C22@2|Bacteria,1Q9H7@1224|Proteobacteria,434DR@68525|delta/epsilon subdivisions,2X8U5@28221|Deltaproteobacteria,2Z0E2@29|Myxococcales	28221|Deltaproteobacteria	S	Gram-negative bacterial TonB protein C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SHD3_k127_4557965_12	1192034.CAP_6961	1.053e-44	166.0	COG0848@1|root,COG0848@2|Bacteria,1N9DN@1224|Proteobacteria,42V0H@68525|delta/epsilon subdivisions,2WQGB@28221|Deltaproteobacteria,2Z0IY@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
SHD3_k127_4557965_13	1254432.SCE1572_43455	2.579e-37	157.0	COG0811@1|root,COG0811@2|Bacteria,1RK2P@1224|Proteobacteria,42TPV@68525|delta/epsilon subdivisions,2X5KN@28221|Deltaproteobacteria,2YXI5@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
SHD3_k127_4557965_9	351160.RCIX1913	5.296e-54	210.0	COG1852@1|root,arCOG02078@2157|Archaea,2XXPW@28890|Euryarchaeota	28890|Euryarchaeota	S	Protein of unknown function DUF116	-	-	-	-	-	-	-	-	-	-	-	-	DUF116
SHD3_k127_4561535_5	555793.WSK_3818	4.445e-17	83.0	2E8X6@1|root,33378@2|Bacteria,1N0Q7@1224|Proteobacteria	1224|Proteobacteria	S	Immunity protein 63	-	-	-	-	-	-	-	-	-	-	-	-	Imm63
SHD3_k127_4561535_1	882378.RBRH_00456	3.427e-126	422.0	COG4584@1|root,COG4584@2|Bacteria,1MW5J@1224|Proteobacteria,2VMZS@28216|Betaproteobacteria,1K35W@119060|Burkholderiaceae	28216|Betaproteobacteria	L	Evidence 2b Function of strongly homologous gene	-	-	-	-	-	-	-	-	-	-	-	-	rve
SHD3_k127_4561535_3	879212.DespoDRAFT_02828	8.775e-73	263.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2MPZT@213118|Desulfobacterales	28221|Deltaproteobacteria	L	PFAM IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SHD3_k127_4561535_4	290397.Adeh_0078	1.286e-37	155.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4561535_0	448385.sce7214	2.935e-139	462.0	COG0642@1|root,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,439XM@68525|delta/epsilon subdivisions,2X1UY@28221|Deltaproteobacteria,2Z0MH@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SHD3_k127_4561535_2	448385.sce7215	4.588e-92	328.0	COG0642@1|root,COG2205@2|Bacteria	448385.sce7215|-	T	PhoQ Sensor	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4561535_6	1961.JOAK01000002_gene1228	6.979e-05	53.0	COG1141@1|root,COG1141@2|Bacteria,2IR4H@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S single cluster domain	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
SHD3_k127_4570057_8	1307759.JOMJ01000003_gene372	2.296e-10	68.0	COG0167@1|root,COG0167@2|Bacteria,1MU7C@1224|Proteobacteria,42M46@68525|delta/epsilon subdivisions,2WJ7G@28221|Deltaproteobacteria,2M8K5@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily	pyrD	GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.3.1.14,1.3.5.2	ko:K00254,ko:K02823,ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01868,R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SHD3_k127_4570057_5	1125863.JAFN01000001_gene358	1.528e-47	186.0	COG0543@1|root,COG0543@2|Bacteria,1RF43@1224|Proteobacteria,42RQK@68525|delta/epsilon subdivisions,2WNJU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
SHD3_k127_4570057_7	448385.sce7253	3.736e-18	97.0	COG0454@1|root,COG0456@2|Bacteria,1RIE6@1224|Proteobacteria,42V77@68525|delta/epsilon subdivisions,2WRQF@28221|Deltaproteobacteria,2YVTX@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
SHD3_k127_4570057_6	246197.MXAN_2686	3.915e-44	184.0	COG0643@1|root,COG0745@1|root,COG2198@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,42M6Q@68525|delta/epsilon subdivisions,2WIRT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	ATP-binding region ATPase domain protein	cheA4	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
SHD3_k127_4570057_9	1388763.O165_001910	0.0004474	52.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,1YX20@136845|Pseudomonas putida group	1236|Gammaproteobacteria	NT	Cache domain	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,dCache_1,dCache_2,sCache_2
SHD3_k127_4570057_3	1192034.CAP_1661	1.881e-118	396.0	COG0784@1|root,COG0784@2|Bacteria,1QAM7@1224|Proteobacteria,43563@68525|delta/epsilon subdivisions,2WZH3@28221|Deltaproteobacteria,2Z24X@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,Response_reg
SHD3_k127_4570057_1	525904.Tter_1474	4.625e-224	734.0	COG0667@1|root,COG0673@1|root,COG0667@2|Bacteria,COG0673@2|Bacteria,2NP86@2323|unclassified Bacteria	2|Bacteria	C	Oxidoreductase family, NAD-binding Rossmann fold	strT	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,GFO_IDH_MocA
SHD3_k127_4570057_0	1122185.N792_08220	2.38e-271	861.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1SJQ1@1236|Gammaproteobacteria,1X5IA@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SHD3_k127_4570057_4	1125863.JAFN01000001_gene1948	5.107e-92	325.0	COG2984@1|root,COG4191@1|root,COG5002@1|root,COG2984@2|Bacteria,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,42MC4@68525|delta/epsilon subdivisions,2WIZU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC_sub_bind,HATPase_c,HisKA,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_4570057_2	404589.Anae109_3792	5.765e-184	592.0	COG1488@1|root,COG1488@2|Bacteria,1R5W0@1224|Proteobacteria,42NQQ@68525|delta/epsilon subdivisions,2WJ4V@28221|Deltaproteobacteria,2YU8U@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C
SHD3_k127_4572960_4	1121920.AUAU01000008_gene1590	3.564e-49	180.0	COG0167@1|root,COG0167@2|Bacteria,3Y464@57723|Acidobacteria	57723|Acidobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
SHD3_k127_4572960_0	1125863.JAFN01000001_gene663	0.0	1567.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,1MVM0@1224|Proteobacteria,42MZ0@68525|delta/epsilon subdivisions,2WJ96@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	poR	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C
SHD3_k127_4572960_1	335543.Sfum_1411	6.196e-122	444.0	COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2WKBU@28221|Deltaproteobacteria,2MQ6I@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13893	ko02010,ko02024,map02010,map02024	M00239,M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
SHD3_k127_4572960_2	335543.Sfum_1413	5.233e-82	284.0	COG0601@1|root,COG0601@2|Bacteria,1NS80@1224|Proteobacteria,42N5D@68525|delta/epsilon subdivisions,2WIRR@28221|Deltaproteobacteria,2MQBC@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
SHD3_k127_4572960_3	530564.Psta_2295	7.414e-68	248.0	COG1173@1|root,COG1173@2|Bacteria,2IXTP@203682|Planctomycetes	203682|Planctomycetes	P	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
SHD3_k127_4582633_0	1123228.AUIH01000001_gene1297	3.102e-74	271.0	COG0366@1|root,COG1874@1|root,COG0366@2|Bacteria,COG1874@2|Bacteria,1R8CV@1224|Proteobacteria,1S0MI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Glycosyl hydrolase family 14	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_14
SHD3_k127_4588332_0	1232410.KI421418_gene2432	0.0	1493.0	COG0243@1|root,COG1104@1|root,COG0243@2|Bacteria,COG1104@2|Bacteria,1MU1C@1224|Proteobacteria,43CDJ@68525|delta/epsilon subdivisions,2X7PE@28221|Deltaproteobacteria,43TE0@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5,Molybdopterin,Molydop_binding
SHD3_k127_4588332_10	448385.sce6352	7.193e-41	161.0	COG2340@1|root,COG2340@2|Bacteria,1RI4E@1224|Proteobacteria,43BDZ@68525|delta/epsilon subdivisions,2X6SG@28221|Deltaproteobacteria,2Z3CJ@29|Myxococcales	28221|Deltaproteobacteria	S	SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains.	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SHD3_k127_4588332_2	1198114.AciX9_1827	1.082e-234	749.0	COG1472@1|root,COG1472@2|Bacteria,3Y2YR@57723|Acidobacteria,2JHNP@204432|Acidobacteriia	204432|Acidobacteriia	G	PFAM glycoside hydrolase family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_4588332_3	756272.Plabr_3955	2.632e-163	527.0	COG0082@1|root,COG0082@2|Bacteria,2IY2Z@203682|Planctomycetes	203682|Planctomycetes	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
SHD3_k127_4588332_1	1125863.JAFN01000001_gene445	5.361e-253	827.0	COG1197@1|root,COG1197@2|Bacteria,1MUXG@1224|Proteobacteria,42N8X@68525|delta/epsilon subdivisions,2WIVR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
SHD3_k127_4588332_12	448385.sce5858	8.32e-22	98.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,cNMP_binding
SHD3_k127_4588332_6	1192034.CAP_6176	2.533e-86	299.0	COG0657@1|root,COG0657@2|Bacteria,1MVRE@1224|Proteobacteria,42XSE@68525|delta/epsilon subdivisions,2WTGG@28221|Deltaproteobacteria,2YYH0@29|Myxococcales	28221|Deltaproteobacteria	I	Pectinacetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	PAE
SHD3_k127_4588332_9	391625.PPSIR1_30474	8.609e-44	176.0	COG0745@1|root,COG0745@2|Bacteria	391625.PPSIR1_30474|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4588332_14	109871.XP_006677476.1	1.874e-05	57.0	2CMDU@1|root,2QQ2C@2759|Eukaryota	2759|Eukaryota	S	Phosphate-induced protein 1 conserved region	-	GO:0005575,GO:0005618,GO:0005623,GO:0005911,GO:0008150,GO:0009505,GO:0009506,GO:0009628,GO:0030054,GO:0030312,GO:0044464,GO:0050896,GO:0055044,GO:0071944,GO:0080167	-	-	-	-	-	-	-	-	-	-	Phi_1
SHD3_k127_4588332_4	1242864.D187_005644	2.224e-96	330.0	COG0515@1|root,COG0515@2|Bacteria,1QTCV@1224|Proteobacteria,437W9@68525|delta/epsilon subdivisions,2X35U@28221|Deltaproteobacteria,2YUE8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4588332_7	1254432.SCE1572_44930	2.033e-57	209.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43AQK@68525|delta/epsilon subdivisions,2X64H@28221|Deltaproteobacteria,2Z00K@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_459688_6	378806.STAUR_1396	2.359e-08	59.0	COG1651@1|root,COG1651@2|Bacteria,1NZPQ@1224|Proteobacteria,42U1T@68525|delta/epsilon subdivisions,2WQH9@28221|Deltaproteobacteria,2YXM2@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SHD3_k127_459688_1	65393.PCC7424_4751	4.29e-56	211.0	COG0823@1|root,COG0823@2|Bacteria,1G6E9@1117|Cyanobacteria	1117|Cyanobacteria	MU	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
SHD3_k127_459688_5	448385.sce0557	5.895e-12	76.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
SHD3_k127_459688_2	448385.sce8901	7.051e-41	158.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_4599558_5	313603.FB2170_08744	5.968e-22	109.0	COG5337@1|root,COG5337@2|Bacteria,4PIRT@976|Bacteroidetes,1IETZ@117743|Flavobacteriia,2PIVA@252356|Maribacter	976|Bacteroidetes	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
SHD3_k127_4599558_6	1123314.AUIO01000003_gene1286	3.151e-06	58.0	COG5036@1|root,COG5036@2|Bacteria,1V1FZ@1239|Firmicutes,4HJFI@91061|Bacilli	91061|Bacilli	P	molecular chaperone	-	-	-	-	-	-	-	-	-	-	-	-	VTC
SHD3_k127_4599558_3	1242864.D187_006455	5.592e-47	177.0	2BK7J@1|root,32EMD@2|Bacteria,1QB42@1224|Proteobacteria,43E56@68525|delta/epsilon subdivisions,2WZRQ@28221|Deltaproteobacteria,2Z2M1@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4599558_4	1242864.D187_010443	1.881e-38	153.0	COG1285@1|root,COG1285@2|Bacteria,1RAIG@1224|Proteobacteria	1224|Proteobacteria	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
SHD3_k127_4599558_0	1242864.D187_010444	8.458e-138	457.0	COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WNES@28221|Deltaproteobacteria,2YU98@29|Myxococcales	28221|Deltaproteobacteria	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
SHD3_k127_4599558_2	1280390.CBQR020000118_gene3102	2.286e-49	183.0	COG2074@1|root,COG2074@2|Bacteria,1VBU6@1239|Firmicutes,4HMME@91061|Bacilli,26X3Y@186822|Paenibacillaceae	91061|Bacilli	G	An automated process has identified a potential problem with this gene model	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4599558_1	1122182.KB903819_gene194	1.645e-108	363.0	COG2706@1|root,COG3227@1|root,COG2706@2|Bacteria,COG3227@2|Bacteria,2IDQA@201174|Actinobacteria,4DBCS@85008|Micromonosporales	201174|Actinobacteria	E	Thermolysin metallopeptidase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	FTP,P_proprotein,Peptidase_M4,Peptidase_M4_C
SHD3_k127_4602727_1	502025.Hoch_0876	1.058e-56	227.0	COG3591@1|root,COG3591@2|Bacteria,1NP6U@1224|Proteobacteria,437JH@68525|delta/epsilon subdivisions,2X2TH@28221|Deltaproteobacteria,2YXUB@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SHD3_k127_4602727_0	378806.STAUR_7771	2.344e-111	398.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42YUY@68525|delta/epsilon subdivisions,2WU6Z@28221|Deltaproteobacteria,2YUNM@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_4602727_2	246197.MXAN_6577	1.312e-08	58.0	COG3391@1|root,COG3391@2|Bacteria,1QX9W@1224|Proteobacteria,43C32@68525|delta/epsilon subdivisions,2X7DQ@28221|Deltaproteobacteria,2YVS2@29|Myxococcales	28221|Deltaproteobacteria	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_4611818_0	1254432.SCE1572_48385	9.614e-187	593.0	COG0015@1|root,COG0015@2|Bacteria,1MV4B@1224|Proteobacteria,42MYS@68525|delta/epsilon subdivisions,2WJ2E@28221|Deltaproteobacteria,2YUJM@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
SHD3_k127_4611818_6	215803.DB30_0689	4.735e-48	188.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42Q51@68525|delta/epsilon subdivisions,2WIMQ@28221|Deltaproteobacteria,2YYKM@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	CarS-like,Metallophos
SHD3_k127_4611818_8	269799.Gmet_3230	1.566e-31	126.0	COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,42TPU@68525|delta/epsilon subdivisions,2WQ1M@28221|Deltaproteobacteria,43UZN@69541|Desulfuromonadales	28221|Deltaproteobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
SHD3_k127_4611818_4	448385.sce0369	1.05e-64	231.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,42R8D@68525|delta/epsilon subdivisions,2WN83@28221|Deltaproteobacteria,2YVI3@29|Myxococcales	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SHD3_k127_4611818_11	633149.Bresu_2189	2.643e-09	63.0	COG1664@1|root,COG1664@2|Bacteria,1MZN0@1224|Proteobacteria,2U5DW@28211|Alphaproteobacteria,2KGZV@204458|Caulobacterales	204458|Caulobacterales	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SHD3_k127_4611818_7	448385.sce0448	3.977e-33	135.0	COG1664@1|root,COG1664@2|Bacteria,1RHS7@1224|Proteobacteria,433TD@68525|delta/epsilon subdivisions,2X9WK@28221|Deltaproteobacteria,2YVM0@29|Myxococcales	28221|Deltaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SHD3_k127_4611818_10	448385.sce0447	1.557e-27	119.0	COG1664@1|root,COG1664@2|Bacteria,1QAFI@1224|Proteobacteria,4351U@68525|delta/epsilon subdivisions,2WZCU@28221|Deltaproteobacteria,2Z1UZ@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SHD3_k127_4611818_3	1254432.SCE1572_03295	4.36e-72	250.0	COG0461@1|root,COG0461@2|Bacteria,1PI8N@1224|Proteobacteria,42QSR@68525|delta/epsilon subdivisions,2WMT5@28221|Deltaproteobacteria,2YV92@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
SHD3_k127_4611818_1	1254432.SCE1572_30460	2.107e-126	458.0	COG3568@1|root,COG3568@2|Bacteria,1PG5A@1224|Proteobacteria,43E4I@68525|delta/epsilon subdivisions,2WZPU@28221|Deltaproteobacteria,2Z2HE@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4611818_5	1192034.CAP_1358	7.652e-49	203.0	COG3055@1|root,COG3055@2|Bacteria	2|Bacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Big_3_2,Kelch_1,Laminin_G_3,Malectin,PKD
SHD3_k127_4611818_9	351607.Acel_0615	1.268e-29	139.0	COG5297@1|root,COG5297@2|Bacteria,2IAE1@201174|Actinobacteria,4EWTP@85013|Frankiales	2|Bacteria	G	cellulose-binding family II	-	-	3.2.1.91	ko:K19668	ko00500,ko01100,ko02020,map00500,map01100,map02020	-	R02886,R11308	RC00799	ko00000,ko00001,ko01000	-	GH6	-	CBM_2,Glyco_hydro_6,fn3
SHD3_k127_4611818_13	1192034.CAP_6604	1.918e-07	55.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_4630346_6	261292.Nit79A3_2352	1.307e-17	100.0	COG0457@1|root,COG1409@1|root,COG3842@1|root,COG0457@2|Bacteria,COG1409@2|Bacteria,COG3842@2|Bacteria,1N8PY@1224|Proteobacteria	1224|Proteobacteria	P	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SHD3_k127_4630346_5	1254432.SCE1572_43555	3.576e-24	121.0	COG1409@1|root,COG1413@1|root,COG5635@1|root,COG1409@2|Bacteria,COG1413@2|Bacteria,COG5635@2|Bacteria	2|Bacteria	T	Nacht domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HEAT_2,Metallophos,NACHT,cNMP_binding
SHD3_k127_4630346_0	1297742.A176_01113	2.846e-103	345.0	COG0705@1|root,COG0705@2|Bacteria,1MYFP@1224|Proteobacteria,42P0V@68525|delta/epsilon subdivisions,2WJGR@28221|Deltaproteobacteria,2YVSU@29|Myxococcales	28221|Deltaproteobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SHD3_k127_4630346_2	483219.LILAB_01395	1.486e-71	263.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,43AJ3@68525|delta/epsilon subdivisions,2X5ZE@28221|Deltaproteobacteria,2Z043@29|Myxococcales	28221|Deltaproteobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PilZ,Pkinase
SHD3_k127_4630346_1	1192034.CAP_1200	1.585e-84	298.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_1200|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4630346_4	448385.sce5260	1.462e-24	114.0	COG4305@1|root,COG5297@1|root,COG4305@2|Bacteria,COG5297@2|Bacteria,1MYW4@1224|Proteobacteria,434JK@68525|delta/epsilon subdivisions,2WYWV@28221|Deltaproteobacteria,2Z0TT@29|Myxococcales	28221|Deltaproteobacteria	G	Rare lipoprotein A (RlpA)-like double-psi beta-barrel	-	-	-	ko:K20628	-	-	-	-	ko00000	-	-	-	DPBB_1,Pollen_allerg_1
SHD3_k127_4630346_9	1088721.NSU_4061	0.0001398	49.0	COG0322@1|root,COG0322@2|Bacteria,1MV38@1224|Proteobacteria,2TT32@28211|Alphaproteobacteria,2K1TK@204457|Sphingomonadales	204457|Sphingomonadales	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_5,UVR,UvrC_HhH_N
SHD3_k127_463136_0	1033743.CAES01000033_gene1025	1.657e-82	278.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,4HGWW@91061|Bacilli,26TEW@186822|Paenibacillaceae	91061|Bacilli	L	DNA-3-methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
SHD3_k127_463136_1	1254432.SCE1572_38360	4.608e-64	237.0	COG1729@1|root,COG3712@1|root,COG1729@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_6,WG_beta_rep
SHD3_k127_463136_2	1254432.SCE1572_20235	5.759e-48	179.0	COG1595@1|root,COG1595@2|Bacteria,1QRBA@1224|Proteobacteria,43DX0@68525|delta/epsilon subdivisions,2WZ3I@28221|Deltaproteobacteria,2Z194@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_463136_5	765913.ThidrDRAFT_3021	0.0003224	51.0	COG3028@1|root,COG3028@2|Bacteria,1MZ4R@1224|Proteobacteria,1S9JJ@1236|Gammaproteobacteria,1WY21@135613|Chromatiales	135613|Chromatiales	S	Belongs to the UPF0307 family	-	-	-	ko:K09889	-	-	-	-	ko00000,ko03009	-	-	-	DUF615
SHD3_k127_463136_4	1121946.AUAX01000020_gene3083	7.929e-14	75.0	COG3266@1|root,COG5297@1|root,COG3266@2|Bacteria,COG5297@2|Bacteria,2GM06@201174|Actinobacteria,4DBIV@85008|Micromonosporales	201174|Actinobacteria	G	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2
SHD3_k127_4633515_4	2850.Phatr12031	1.082e-31	128.0	COG0299@1|root,KOG3076@2759|Eukaryota,2XBM4@2836|Bacillariophyta	2836|Bacillariophyta	G	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
SHD3_k127_4633515_1	448385.sce4032	3.983e-52	203.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_4633515_2	448385.sce4032	1.486e-49	193.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_4633515_3	926549.KI421517_gene2159	3.423e-47	189.0	COG2017@1|root,COG2017@2|Bacteria	2|Bacteria	G	converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim,DUF4380
SHD3_k127_4633515_0	290397.Adeh_1281	8.861e-114	374.0	COG1045@1|root,COG1045@2|Bacteria,1MVFX@1224|Proteobacteria,42MND@68525|delta/epsilon subdivisions,2WJC3@28221|Deltaproteobacteria,2YWX3@29|Myxococcales	28221|Deltaproteobacteria	E	Bacterial transferase hexapeptide (six repeats)	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
SHD3_k127_4633515_5	1140.Synpcc7942_0085	3.631e-31	134.0	COG0637@1|root,COG0637@2|Bacteria,1G7W5@1117|Cyanobacteria	1117|Cyanobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
SHD3_k127_4639515_6	237609.PSAKL28_29660	4.675e-26	110.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,1RRWV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
SHD3_k127_4639515_2	582899.Hden_3207	1.34e-91	309.0	COG0164@1|root,COG0164@2|Bacteria,1RA65@1224|Proteobacteria,2U73X@28211|Alphaproteobacteria,3N6VY@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
SHD3_k127_4639515_4	1485545.JQLW01000008_gene2054	7.135e-33	143.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	pqqE	-	-	ko:K06139,ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,PqqD,Radical_SAM,SPASM
SHD3_k127_4639515_9	519989.ECTPHS_13727	0.0001871	52.0	COG1493@1|root,COG1493@2|Bacteria,1QWDD@1224|Proteobacteria,1T3TI@1236|Gammaproteobacteria,1WWBI@135613|Chromatiales	135613|Chromatiales	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4639515_3	1144275.COCOR_04600	2.697e-39	149.0	COG0025@1|root,COG0025@2|Bacteria,1QTZ5@1224|Proteobacteria	1224|Proteobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SHD3_k127_4639515_0	391625.PPSIR1_35722	1.251e-250	794.0	COG2183@1|root,COG2183@2|Bacteria,1MUA7@1224|Proteobacteria,42M9U@68525|delta/epsilon subdivisions,2WJ4X@28221|Deltaproteobacteria,2YUNF@29|Myxococcales	28221|Deltaproteobacteria	K	Tex-like protein N-terminal domain	tex	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
SHD3_k127_4639515_7	448385.sce6854	2.895e-05	55.0	COG3055@1|root,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
SHD3_k127_4639515_5	667632.KB890176_gene4711	4.447e-26	113.0	2E5QB@1|root,330EW@2|Bacteria,1N890@1224|Proteobacteria,2VVXS@28216|Betaproteobacteria,1K8E0@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF2844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2844
SHD3_k127_4639515_1	1005048.CFU_1855	3.096e-98	334.0	28I2U@1|root,2Z86S@2|Bacteria,1P33F@1224|Proteobacteria,2VP36@28216|Betaproteobacteria,476IG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF3443)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3443
SHD3_k127_4650379_2	404589.Anae109_1011	5.156e-84	285.0	COG0730@1|root,COG0730@2|Bacteria,1MXNM@1224|Proteobacteria,42KZF@68525|delta/epsilon subdivisions,2WSRV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
SHD3_k127_4650379_0	1163617.SCD_n01760	3.899e-148	478.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria,2VINV@28216|Betaproteobacteria	28216|Betaproteobacteria	C	Radical SAM	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SHD3_k127_4650379_1	448385.sce7975	1.11e-93	313.0	COG0689@1|root,COG0689@2|Bacteria,1MVFZ@1224|Proteobacteria,42NEX@68525|delta/epsilon subdivisions,2WJ1Y@28221|Deltaproteobacteria,2YUXF@29|Myxococcales	28221|Deltaproteobacteria	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
SHD3_k127_4650379_4	1207058.L53_07195	7.651e-47	177.0	COG0602@1|root,COG0602@2|Bacteria,1MUJ2@1224|Proteobacteria,2TU1S@28211|Alphaproteobacteria,43WAY@69657|Hyphomonadaceae	28211|Alphaproteobacteria	H	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	queE	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
SHD3_k127_4650379_3	448385.sce8140	4.34e-81	284.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,Sulfatase
SHD3_k127_4652628_4	1192034.CAP_7801	1.265e-66	230.0	2BS7F@1|root,32M8R@2|Bacteria,1Q33Y@1224|Proteobacteria,433XP@68525|delta/epsilon subdivisions,2X2HG@28221|Deltaproteobacteria,2YXTX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4652628_3	1192034.CAP_7799	7.685e-78	279.0	COG1360@1|root,COG1360@2|Bacteria	2|Bacteria	N	Flagellar Motor Protein	-	-	-	ko:K02557	ko02030,ko02040,map02030,map02040	-	-	-	ko00000,ko00001,ko02000,ko02035	1.A.30.1	-	-	OmpA
SHD3_k127_4652628_1	448385.sce1705	2.282e-83	288.0	COG0248@1|root,COG0248@2|Bacteria,1MV35@1224|Proteobacteria,42NIH@68525|delta/epsilon subdivisions,2WQJT@28221|Deltaproteobacteria,2YV3J@29|Myxococcales	28221|Deltaproteobacteria	FP	Ppx GppA	gppA-1	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
SHD3_k127_4652628_0	1192034.CAP_7797	5.877e-91	302.0	COG1329@1|root,COG1329@2|Bacteria,1MWI2@1224|Proteobacteria,42RXS@68525|delta/epsilon subdivisions,2WNA0@28221|Deltaproteobacteria,2YVAI@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator, CarD family	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
SHD3_k127_4652628_5	103733.JNYO01000013_gene4363	3.393e-50	188.0	COG0710@1|root,COG0710@2|Bacteria	2|Bacteria	E	3-dehydroquinate dehydratase activity	aroD	GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617	1.1.1.25,4.2.1.10	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413,R03084	RC00206,RC00848	ko00000,ko00001,ko00002,ko01000	-	-	iEC042_1314.EC042_1860	DHquinase_I,Shikimate_DH,Shikimate_dh_N
SHD3_k127_4652628_7	1254432.SCE1572_10655	3.788e-11	67.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	surA	-	5.2.1.8	ko:K02597,ko:K03769,ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N,SurA_N_3
SHD3_k127_4653153_3	103733.JNYO01000047_gene7340	3.444e-32	139.0	COG4638@1|root,COG4638@2|Bacteria,2I2DT@201174|Actinobacteria,4DYBY@85010|Pseudonocardiales	201174|Actinobacteria	P	PFAM Rieske 2Fe-2S domain	crtV	-	-	-	-	-	-	-	-	-	-	-	Rieske
SHD3_k127_4653153_4	373994.Riv7116_1184	3.386e-23	108.0	COG4704@1|root,COG4704@2|Bacteria,1G7Y9@1117|Cyanobacteria,1HP3K@1161|Nostocales	1117|Cyanobacteria	S	Uncharacterized protein conserved in bacteria (DUF2141)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2141
SHD3_k127_4653153_2	1121405.dsmv_1254	4.222e-35	138.0	COG0748@1|root,COG0748@2|Bacteria,1N2JV@1224|Proteobacteria,42TYW@68525|delta/epsilon subdivisions,2WQEM@28221|Deltaproteobacteria,2MKGM@213118|Desulfobacterales	28221|Deltaproteobacteria	P	PFAM Pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
SHD3_k127_4653153_1	1304883.KI912532_gene360	8.723e-40	160.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1R2NF@1224|Proteobacteria,2VJDG@28216|Betaproteobacteria,2KW35@206389|Rhodocyclales	206389|Rhodocyclales	K	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
SHD3_k127_4653153_0	1242864.D187_010367	4.168e-50	182.0	COG3349@1|root,COG3349@2|Bacteria,1RAVN@1224|Proteobacteria,433WH@68525|delta/epsilon subdivisions,2X3VQ@28221|Deltaproteobacteria,2YX9K@29|Myxococcales	28221|Deltaproteobacteria	Q	FAD dependent oxidoreductase	-	-	-	ko:K09879	ko00906,map00906	-	R07541,R07560,R07857,R07858	RC01901,RC01965	ko00000,ko00001	-	-	-	Amino_oxidase
SHD3_k127_46539_0	517418.Ctha_1771	3.82e-102	341.0	COG2203@1|root,COG2206@1|root,COG2203@2|Bacteria,COG2206@2|Bacteria	2|Bacteria	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	3.1.4.17	ko:K01120	ko00230,map00230	-	R00191,R01234	RC00296	ko00000,ko00001,ko01000	-	-	-	GAF,GAF_2,GerE,HATPase_c,HD,HD_5,HisKA
SHD3_k127_46539_2	313606.M23134_07899	5.808e-13	80.0	COG1716@1|root,COG1716@2|Bacteria,4P7PV@976|Bacteroidetes	976|Bacteroidetes	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_46539_1	935866.JAER01000058_gene253	5.745e-38	155.0	COG0631@1|root,COG0631@2|Bacteria,2IPUA@201174|Actinobacteria,4DTN9@85009|Propionibacteriales	201174|Actinobacteria	T	Protein phosphatase 2C	-	-	-	-	-	-	-	-	-	-	-	-	PP2C_2
SHD3_k127_46539_3	926569.ANT_14090	5.121e-06	49.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,RDD,Yop-YscD_cpl
SHD3_k127_4655699_3	290397.Adeh_3668	2.142e-16	87.0	COG0475@1|root,COG0475@2|Bacteria,1RB9F@1224|Proteobacteria,42UIK@68525|delta/epsilon subdivisions,2X5D2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
SHD3_k127_4655699_1	226186.BT_2345	9.758e-34	140.0	COG1266@1|root,COG1266@2|Bacteria,4NRAH@976|Bacteroidetes,2FS5H@200643|Bacteroidia,4ATCX@815|Bacteroidaceae	976|Bacteroidetes	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SHD3_k127_4655699_0	880072.Desac_2549	2.101e-117	383.0	COG0500@1|root,COG2226@2|Bacteria,1RDQI@1224|Proteobacteria,42SIB@68525|delta/epsilon subdivisions,2WPCP@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_4655699_4	1196322.A370_03657	5.359e-08	57.0	COG1402@1|root,COG1402@2|Bacteria,1TT2A@1239|Firmicutes,24FDY@186801|Clostridia	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
SHD3_k127_4655699_2	1122137.AQXF01000005_gene990	2.118e-32	142.0	COG4242@1|root,COG4242@2|Bacteria,1R6CH@1224|Proteobacteria,2U8MQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	PQ	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
SHD3_k127_4655699_5	1038859.AXAU01000037_gene5353	6.142e-05	47.0	COG0810@1|root,COG0810@2|Bacteria,1MZXC@1224|Proteobacteria,2UCBT@28211|Alphaproteobacteria,3JURP@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Gram-negative bacterial TonB protein C-terminal	tonB	-	-	ko:K03832	-	-	-	-	ko00000,ko02000	2.C.1.1	-	-	TonB_2,TonB_C
SHD3_k127_4671139_0	1254432.SCE1572_31760	1.042e-88	327.0	COG1609@1|root,COG2208@1|root,COG1609@2|Bacteria,COG2208@2|Bacteria,1RHRV@1224|Proteobacteria,43ARR@68525|delta/epsilon subdivisions,2X65U@28221|Deltaproteobacteria,2Z0U1@29|Myxococcales	28221|Deltaproteobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_3,SpoIIE
SHD3_k127_4671139_1	215803.DB30_0855	4.557e-20	100.0	COG0491@1|root,COG0491@2|Bacteria,1Q427@1224|Proteobacteria,439VM@68525|delta/epsilon subdivisions,2X59N@28221|Deltaproteobacteria,2Z0AV@29|Myxococcales	28221|Deltaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SHD3_k127_4678721_4	395493.BegalDRAFT_0912	3.284e-35	153.0	COG1948@1|root,COG4880@2|Bacteria,1P2CI@1224|Proteobacteria	1224|Proteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SHD3_k127_4678721_2	1117943.SFHH103_01763	4.946e-100	346.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,2TSQU@28211|Alphaproteobacteria,4BB7Q@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF3520)	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SHD3_k127_4678721_1	1254432.SCE1572_20375	1.23e-100	338.0	2FIE8@1|root,34A6F@2|Bacteria,1P3KN@1224|Proteobacteria,431Y1@68525|delta/epsilon subdivisions,2WWQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4423
SHD3_k127_4678721_0	246197.MXAN_5220	1.705e-107	357.0	COG0122@1|root,COG5483@1|root,COG0122@2|Bacteria,COG5483@2|Bacteria,1PERA@1224|Proteobacteria,435TA@68525|delta/epsilon subdivisions,2X08G@28221|Deltaproteobacteria,2Z18M@29|Myxococcales	28221|Deltaproteobacteria	L	endonuclease III	-	-	3.2.2.21	ko:K01247	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
SHD3_k127_4678721_3	330214.NIDE1115	3.023e-43	173.0	COG0265@1|root,COG1262@1|root,COG0265@2|Bacteria,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	1.14.99.50	ko:K18912	ko00340,map00340	-	R11013	RC03323,RC03324	ko00000,ko00001,ko01000	-	-	-	FGE-sulfatase,Trypsin_2
SHD3_k127_4685863_0	391625.PPSIR1_18642	1.613e-36	159.0	COG2730@1|root,COG2730@2|Bacteria,1N21U@1224|Proteobacteria,435AG@68525|delta/epsilon subdivisions,2WZMJ@28221|Deltaproteobacteria,2Z2DK@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_4685863_1	448385.sce5448	2.76e-32	133.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_4685863_3	43151.ADAC002015-PA	1.981e-18	96.0	COG2272@1|root,KOG1214@2759|Eukaryota,3A7ZK@33154|Opisthokonta,3BTKQ@33208|Metazoa,3DABX@33213|Bilateria,420PX@6656|Arthropoda,3SP0X@50557|Insecta,456FA@7147|Diptera,45I4S@7148|Nematocera	33208|Metazoa	O	Pacifastin inhibitor (LCMII)	-	-	-	-	-	-	-	-	-	-	-	-	Pacifastin_I
SHD3_k127_4691745_8	316067.Geob_2544	2.679e-25	115.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1MV6C@1224|Proteobacteria,42MF5@68525|delta/epsilon subdivisions,2WKPR@28221|Deltaproteobacteria,43U25@69541|Desulfuromonadales	28221|Deltaproteobacteria	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
SHD3_k127_4691745_5	543632.JOJL01000029_gene3629	1.9e-61	222.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4D8MQ@85008|Micromonosporales	201174|Actinobacteria	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
SHD3_k127_4691745_9	497964.CfE428DRAFT_5379	1.813e-12	72.0	COG0236@1|root,COG0236@2|Bacteria,46TAW@74201|Verrucomicrobia	74201|Verrucomicrobia	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SHD3_k127_4691745_4	203275.BFO_1132	4.028e-73	263.0	COG0304@1|root,COG0304@2|Bacteria,4NFC8@976|Bacteroidetes,2FPUI@200643|Bacteroidia,22WV4@171551|Porphyromonadaceae	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	2.3.1.41	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_2,Ketoacyl-synt_C,ketoacyl-synt
SHD3_k127_4691745_10	888059.HMPREF9071_2230	3.931e-11	76.0	COG0304@1|root,COG0304@2|Bacteria,4NEU6@976|Bacteroidetes,1HXNF@117743|Flavobacteriia,1ERGW@1016|Capnocytophaga	976|Bacteroidetes	IQ	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_2,ketoacyl-synt
SHD3_k127_4691745_3	56780.SYN_02127	7.366e-79	270.0	COG1028@1|root,COG1028@2|Bacteria,1MU6X@1224|Proteobacteria,42MB9@68525|delta/epsilon subdivisions,2WJ64@28221|Deltaproteobacteria,2MQF5@213462|Syntrophobacterales	28221|Deltaproteobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
SHD3_k127_4691745_7	1192124.LIG30_1132	6.571e-34	151.0	COG0318@1|root,COG0764@1|root,COG0318@2|Bacteria,COG0764@2|Bacteria,1MXPB@1224|Proteobacteria,2VIYA@28216|Betaproteobacteria,1JZSG@119060|Burkholderiaceae	28216|Betaproteobacteria	IQ	amp-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,FabA
SHD3_k127_4691745_2	1033734.CAET01000030_gene4009	2.09e-106	368.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,1ZAQW@1386|Bacillus	91061|Bacilli	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	6.4.1.6	ko:K10855	-	-	-	-	ko00000,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SHD3_k127_4691745_6	266117.Rxyl_1849	3.605e-37	149.0	COG4647@1|root,COG4647@2|Bacteria,2IG9M@201174|Actinobacteria	201174|Actinobacteria	Q	Acetone carboxylase gamma subunit	-	-	-	-	-	-	-	-	-	-	-	-	Acetone_carb_G
SHD3_k127_4691745_0	1033734.CAET01000030_gene4007	1.23e-231	739.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,4HB8X@91061|Bacilli,1ZAQW@1386|Bacillus	91061|Bacilli	EQ	COG0145 N-methylhydantoinase A acetone carboxylase, beta subunit	-	-	6.4.1.6	ko:K10855	-	-	-	-	ko00000,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
SHD3_k127_4691745_1	1033734.CAET01000030_gene4006	1.432e-203	654.0	COG0146@1|root,COG0146@2|Bacteria,1U1N7@1239|Firmicutes,4HBKB@91061|Bacilli,1ZDFI@1386|Bacillus	91061|Bacilli	EQ	COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	Hydantoinase_B
SHD3_k127_4694856_1	1254432.SCE1572_38200	2.626e-265	828.0	COG0443@1|root,COG0443@2|Bacteria,1MXX7@1224|Proteobacteria,42NWU@68525|delta/epsilon subdivisions,2WKQQ@28221|Deltaproteobacteria,2YUNI@29|Myxococcales	28221|Deltaproteobacteria	O	MreB/Mbl protein	dnaK4	-	-	-	-	-	-	-	-	-	-	-	HSP70
SHD3_k127_4694856_15	869210.Marky_1177	7.586e-55	205.0	COG0120@1|root,COG0120@2|Bacteria,1WIR4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
SHD3_k127_4694856_11	1242864.D187_006013	1.739e-89	301.0	COG4221@1|root,COG4221@2|Bacteria,1MUF8@1224|Proteobacteria	1224|Proteobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_4694856_7	1242864.D187_005576	3.623e-125	411.0	COG0604@1|root,COG0604@2|Bacteria,1QY04@1224|Proteobacteria,43AHJ@68525|delta/epsilon subdivisions,2X5XS@28221|Deltaproteobacteria,2YUNY@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
SHD3_k127_4694856_16	448385.sce0899	1.171e-50	182.0	COG1293@1|root,COG1293@2|Bacteria,1P028@1224|Proteobacteria	1224|Proteobacteria	K	Fibronectin fibrinogen-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
SHD3_k127_4694856_12	1254432.SCE1572_45365	1.504e-84	296.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	DNase-RNase,PDZ_2,Trypsin_2
SHD3_k127_4694856_8	1192034.CAP_2145	2.426e-124	406.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,42QUA@68525|delta/epsilon subdivisions,2WMWM@28221|Deltaproteobacteria,2YU7P@29|Myxococcales	28221|Deltaproteobacteria	T	Protein serine threonine phosphatase	pph1	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SHD3_k127_4694856_13	448385.sce7897	1.195e-78	270.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YVKS@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_4694856_9	1192034.CAP_7270	6.915e-112	378.0	COG1232@1|root,COG1232@2|Bacteria,1R0KQ@1224|Proteobacteria,42NBG@68525|delta/epsilon subdivisions,2WKMN@28221|Deltaproteobacteria,2YUWM@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemY	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
SHD3_k127_4694856_22	926566.Terro_2695	1.597e-14	79.0	COG4783@1|root,COG4783@2|Bacteria,3Y5FY@57723|Acidobacteria,2JJX1@204432|Acidobacteriia	204432|Acidobacteriia	S	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	TPR_17,TPR_19
SHD3_k127_4694856_3	448385.sce5027	1.192e-242	756.0	COG2006@1|root,COG2006@2|Bacteria,1NSD4@1224|Proteobacteria,42YV4@68525|delta/epsilon subdivisions,2WTK6@28221|Deltaproteobacteria,2YWVS@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_4694856_2	448385.sce0891	1.043e-242	775.0	COG0210@1|root,COG0210@2|Bacteria,1MU0G@1224|Proteobacteria,42MKU@68525|delta/epsilon subdivisions,2WJR3@28221|Deltaproteobacteria,2YU2G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
SHD3_k127_4694856_17	448385.sce0004	1.193e-47	180.0	COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,42TM2@68525|delta/epsilon subdivisions,2WQ0U@28221|Deltaproteobacteria,2YVHI@29|Myxococcales	28221|Deltaproteobacteria	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
SHD3_k127_4694856_4	639282.DEFDS_2114	2.757e-231	731.0	COG0443@1|root,COG0443@2|Bacteria,2GEXS@200930|Deferribacteres	200930|Deferribacteres	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
SHD3_k127_4694856_5	1254432.SCE1572_00005	5.652e-182	585.0	COG0593@1|root,COG0593@2|Bacteria,1MU5H@1224|Proteobacteria,42MA0@68525|delta/epsilon subdivisions,2WJAT@28221|Deltaproteobacteria,2YTT2@29|Myxococcales	28221|Deltaproteobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
SHD3_k127_4694856_14	448385.sce9367	8.513e-73	261.0	294S9@1|root,2ZS5H@2|Bacteria,1P6YX@1224|Proteobacteria,4330Z@68525|delta/epsilon subdivisions,2WY8M@28221|Deltaproteobacteria,2YZRX@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4694856_19	448385.sce9251	8.475e-32	131.0	COG2332@1|root,COG2332@2|Bacteria	2|Bacteria	O	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH	ccmE	-	-	ko:K02197	-	-	-	-	ko00000	-	-	-	CcmE
SHD3_k127_4694856_6	1254432.SCE1572_46550	1.844e-142	459.0	COG0407@1|root,COG0407@2|Bacteria,1MUG1@1224|Proteobacteria,42MV9@68525|delta/epsilon subdivisions,2WJZK@28221|Deltaproteobacteria,2YTSB@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0016	URO-D
SHD3_k127_4694856_0	448385.sce2753	0.0	1512.0	COG0515@1|root,COG3899@1|root,COG0515@2|Bacteria,COG3899@2|Bacteria,1MWVZ@1224|Proteobacteria,438G1@68525|delta/epsilon subdivisions,2X3QZ@28221|Deltaproteobacteria,2YWVV@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,PEGA,Pkinase,TPR_12
SHD3_k127_4706953_1	1121396.KB893113_gene3201	1.735e-67	237.0	COG4804@1|root,COG4804@2|Bacteria,1NBWK@1224|Proteobacteria,42NXR@68525|delta/epsilon subdivisions,2WN7B@28221|Deltaproteobacteria,2MN5N@213118|Desulfobacterales	28221|Deltaproteobacteria	V	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
SHD3_k127_4706953_0	59374.Fisuc_0389	4.403e-94	326.0	COG3507@1|root,COG5297@1|root,COG3507@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.8	ko:K01181,ko:K09955	-	-	-	-	ko00000,ko01000	-	-	-	ArabFuran-catal,CBM_4_9,CBM_6,DUF1080,DUF4091,Dockerin_1,F5_F8_type_C,Glyco_hydro_10,Glyco_hydro_127,Glyco_hydro_43,Laminin_G_3,RicinB_lectin_2
SHD3_k127_4706953_3	502025.Hoch_2959	3.599e-06	53.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SHD3_k127_4709351_2	706587.Desti_2948	3.302e-17	82.0	COG0069@1|root,COG0069@2|Bacteria	2|Bacteria	E	glutamate synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
SHD3_k127_4709351_0	880072.Desac_1036	9.967e-202	642.0	COG0069@1|root,COG1145@1|root,COG0069@2|Bacteria,COG1145@2|Bacteria,1MU7B@1224|Proteobacteria,42MF7@68525|delta/epsilon subdivisions,2WJBR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Glutamate synthase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Glu_synthase
SHD3_k127_4709351_1	1265505.ATUG01000002_gene1765	3.893e-178	569.0	COG0067@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0070@2|Bacteria,1NZ4D@1224|Proteobacteria,43B3T@68525|delta/epsilon subdivisions,2X6HR@28221|Deltaproteobacteria,2MN6R@213118|Desulfobacterales	28221|Deltaproteobacteria	E	GXGXG motif	-	-	-	-	-	-	-	-	-	-	-	-	GATase_6,GXGXG
SHD3_k127_4741645_7	1267535.KB906767_gene1468	2.618e-17	89.0	COG0577@1|root,COG0577@2|Bacteria,3Y3K0@57723|Acidobacteria	57723|Acidobacteria	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SHD3_k127_4741645_2	483219.LILAB_30180	8.936e-62	222.0	COG4221@1|root,COG4221@2|Bacteria,1MUU6@1224|Proteobacteria,42YQ8@68525|delta/epsilon subdivisions,2WU8K@28221|Deltaproteobacteria,2YZNE@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_4741645_8	1173264.KI913949_gene42	3.421e-06	61.0	COG2319@1|root,COG2319@2|Bacteria,1FZVW@1117|Cyanobacteria	1117|Cyanobacteria	A	WD domain, G-beta repeat	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C14,WD40
SHD3_k127_4741645_9	1254432.SCE1572_45475	9.971e-06	59.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
SHD3_k127_4741645_1	1192034.CAP_2598	1.91e-71	270.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42Q78@68525|delta/epsilon subdivisions,2WJHK@28221|Deltaproteobacteria,2YU6Z@29|Myxococcales	28221|Deltaproteobacteria	S	protein containing a von Willebrand factor type A (vWA) domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	DUF3520,VWA,vWF_A
SHD3_k127_4741645_5	1408254.T458_14775	8.034e-24	104.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
SHD3_k127_4741645_4	197221.22295469	1.241e-30	136.0	COG0845@1|root,COG0845@2|Bacteria,1G01U@1117|Cyanobacteria	1117|Cyanobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_D23,OEP
SHD3_k127_4741645_0	690850.Desaf_3773	9.639e-81	276.0	COG1136@1|root,COG1136@2|Bacteria,1MU45@1224|Proteobacteria,42QF5@68525|delta/epsilon subdivisions,2WK2K@28221|Deltaproteobacteria,2M96E@213115|Desulfovibrionales	28221|Deltaproteobacteria	V	pfam abc	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_4741645_6	1220534.B655_1340	3.736e-22	111.0	COG0577@1|root,arCOG02312@2157|Archaea,2XUEE@28890|Euryarchaeota,23PE0@183925|Methanobacteria	183925|Methanobacteria	P	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SHD3_k127_4741645_3	1384054.N790_02500	1.488e-47	186.0	COG0577@1|root,COG0577@2|Bacteria,1MX7X@1224|Proteobacteria,1RRH7@1236|Gammaproteobacteria,1X430@135614|Xanthomonadales	135614|Xanthomonadales	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SHD3_k127_4749441_2	378806.STAUR_2228	1.799e-86	302.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2YU5P@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SHD3_k127_4749441_0	448385.sce7048	1.56e-114	377.0	COG1198@1|root,COG1198@2|Bacteria,1MUUZ@1224|Proteobacteria,42MNH@68525|delta/epsilon subdivisions,2WJ4G@28221|Deltaproteobacteria,2YU5P@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
SHD3_k127_4749441_4	1297742.A176_01399	6.022e-19	93.0	2C852@1|root,32YB2@2|Bacteria,1N9HY@1224|Proteobacteria,42WCG@68525|delta/epsilon subdivisions,2WS1H@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4136)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4136
SHD3_k127_4749441_1	448385.sce5153	1.13e-89	314.0	29X07@1|root,30ING@2|Bacteria,1PDK6@1224|Proteobacteria,43E67@68525|delta/epsilon subdivisions,2WZUQ@28221|Deltaproteobacteria,2Z2SP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4749441_7	1340493.JNIF01000003_gene3146	6.728e-08	58.0	COG1538@1|root,COG1538@2|Bacteria,3Y3KB@57723|Acidobacteria	57723|Acidobacteria	MU	outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SHD3_k127_4749441_8	471854.Dfer_3160	3.714e-05	49.0	COG0841@1|root,COG0845@1|root,COG0841@2|Bacteria,COG0845@2|Bacteria,4NG7I@976|Bacteroidetes,47NV5@768503|Cytophagia	976|Bacteroidetes	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran,HlyD_D23
SHD3_k127_4749441_5	1267535.KB906767_gene2008	2.982e-09	68.0	COG0845@1|root,COG0845@2|Bacteria,3Y2U2@57723|Acidobacteria,2JMFW@204432|Acidobacteriia	204432|Acidobacteriia	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SHD3_k127_4749441_6	234267.Acid_5519	3.667e-09	59.0	COG0845@1|root,COG0845@2|Bacteria,3Y2U2@57723|Acidobacteria	57723|Acidobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SHD3_k127_4749441_3	1242864.D187_005998	4.204e-62	233.0	COG3746@1|root,COG3746@2|Bacteria,1R9AP@1224|Proteobacteria	1224|Proteobacteria	P	PFAM Phosphate-selective porin O	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
SHD3_k127_47526_8	1089553.Tph_c25870	3.15e-14	72.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,42EPJ@68295|Thermoanaerobacterales	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
SHD3_k127_47526_9	1235796.C815_01203	8.285e-08	55.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes	1239|Firmicutes	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
SHD3_k127_47526_7	1254432.SCE1572_03040	9.126e-32	133.0	COG0690@1|root,COG0690@2|Bacteria,1QARP@1224|Proteobacteria,4359C@68525|delta/epsilon subdivisions,2WZKH@28221|Deltaproteobacteria,2Z2BF@29|Myxococcales	28221|Deltaproteobacteria	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
SHD3_k127_47526_3	1192034.CAP_5625	1.794e-74	257.0	COG0250@1|root,COG0250@2|Bacteria,1MU14@1224|Proteobacteria,42MPQ@68525|delta/epsilon subdivisions,2WMP6@28221|Deltaproteobacteria,2YV7X@29|Myxococcales	28221|Deltaproteobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
SHD3_k127_47526_4	448385.sce0406	8.948e-62	215.0	COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,42RE7@68525|delta/epsilon subdivisions,2WNAH@28221|Deltaproteobacteria,2YV5W@29|Myxococcales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
SHD3_k127_47526_2	1254432.SCE1572_03055	1.509e-97	324.0	COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,42MZP@68525|delta/epsilon subdivisions,2WJ1Z@28221|Deltaproteobacteria,2YTSV@29|Myxococcales	28221|Deltaproteobacteria	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
SHD3_k127_47526_5	1254432.SCE1572_03060	1e-56	202.0	COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,42R1J@68525|delta/epsilon subdivisions,2WQE8@28221|Deltaproteobacteria,2YVQE@29|Myxococcales	28221|Deltaproteobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
SHD3_k127_47526_6	1122962.AULH01000006_gene3167	6.744e-43	160.0	COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2U9FX@28211|Alphaproteobacteria,36YD6@31993|Methylocystaceae	28211|Alphaproteobacteria	J	Ribosomal protein L7/L12 dimerisation domain	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
SHD3_k127_47526_0	1192034.CAP_5630	0.0	2261.0	COG0085@1|root,COG0085@2|Bacteria,1MUC4@1224|Proteobacteria,43DMZ@68525|delta/epsilon subdivisions,2WIW5@28221|Deltaproteobacteria,2YUEA@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
SHD3_k127_47526_1	448385.sce0411	3.789e-239	742.0	COG0086@1|root,COG0086@2|Bacteria,1MU3M@1224|Proteobacteria,42NAW@68525|delta/epsilon subdivisions,2WISU@28221|Deltaproteobacteria,2YUJI@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
SHD3_k127_4755264_0	349521.HCH_00108	1.209e-211	675.0	COG1894@1|root,COG1905@1|root,COG1894@2|Bacteria,COG1905@2|Bacteria,1MV8F@1224|Proteobacteria,1RMUD@1236|Gammaproteobacteria,1XH7K@135619|Oceanospirillales	135619|Oceanospirillales	C	NADH-quinone oxidoreductase subunit F	-	-	1.12.1.2	ko:K18005	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,NADH_4Fe-4S
SHD3_k127_4755264_2	349521.HCH_00107	8.586e-82	278.0	COG3383@1|root,COG3383@2|Bacteria,1MXTC@1224|Proteobacteria,1RZDX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	NADH ubiquinone oxidoreductase	-	-	1.12.1.2	ko:K18006,ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Fer2_4,Fer4_15,NADH-G_4Fe-4S_3
SHD3_k127_4755264_3	349521.HCH_00106	1.343e-72	250.0	COG1941@1|root,COG1941@2|Bacteria,1NS0E@1224|Proteobacteria,1RW0G@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Coenzyme F420-reducing hydrogenase, gamma subunit	hoxY	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
SHD3_k127_4755264_1	349521.HCH_00105	1.27e-172	549.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,1T20U@1236|Gammaproteobacteria,1XPVQ@135619|Oceanospirillales	135619|Oceanospirillales	C	Nickel-dependent hydrogenase	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
SHD3_k127_4756997_4	1242864.D187_002633	1.018e-46	174.0	COG2944@1|root,COG2944@2|Bacteria,1Q6DX@1224|Proteobacteria,432Z1@68525|delta/epsilon subdivisions,2WXF7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MqsA_antitoxin
SHD3_k127_4756997_3	391625.PPSIR1_11130	4.135e-54	201.0	COG1262@1|root,COG1262@2|Bacteria,1QADB@1224|Proteobacteria,43503@68525|delta/epsilon subdivisions,2X93Q@28221|Deltaproteobacteria,2Z1R3@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_4756997_2	1254432.SCE1572_09950	7.189e-60	225.0	COG4826@1|root,COG4826@2|Bacteria,1REGX@1224|Proteobacteria,42T9N@68525|delta/epsilon subdivisions,2WPDB@28221|Deltaproteobacteria,2YV97@29|Myxococcales	28221|Deltaproteobacteria	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SHD3_k127_4756997_5	59374.Fisuc_1992	3.435e-34	142.0	COG3093@1|root,COG3093@2|Bacteria	2|Bacteria	K	addiction module antidote protein HigA	-	-	-	ko:K07110,ko:K21686	-	-	-	-	ko00000,ko03000	-	-	-	DUF2083,DUF4423,HTH_3,HTH_31,Peptidase_M78
SHD3_k127_4756997_9	404589.Anae109_0078	4.505e-05	55.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2YTXF@29|Myxococcales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SHD3_k127_4756997_1	290397.Adeh_0141	2.302e-100	343.0	COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria,2YU4K@29|Myxococcales	28221|Deltaproteobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
SHD3_k127_4756997_7	335543.Sfum_2513	3.548e-16	86.0	COG1994@1|root,COG1994@2|Bacteria,1NPJC@1224|Proteobacteria	1224|Proteobacteria	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4756997_0	448385.sce9281	4.049e-155	503.0	COG3344@1|root,COG3344@2|Bacteria,1MVI1@1224|Proteobacteria,42Y93@68525|delta/epsilon subdivisions,2WU1Y@28221|Deltaproteobacteria,2YWK2@29|Myxococcales	28221|Deltaproteobacteria	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
SHD3_k127_475986_3	671143.DAMO_2148	2.375e-36	142.0	COG4914@1|root,COG4914@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
SHD3_k127_475986_1	448385.sce7249	2.095e-111	361.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SHD3_k127_475986_2	448385.sce7248	5.587e-88	292.0	COG2018@1|root,COG2018@2|Bacteria,1RDN5@1224|Proteobacteria,42S13@68525|delta/epsilon subdivisions,2WNKB@28221|Deltaproteobacteria,2YV9Q@29|Myxococcales	28221|Deltaproteobacteria	S	Roadblock/LC7 domain	mglB	-	-	-	-	-	-	-	-	-	-	-	Robl_LC7
SHD3_k127_475986_0	1254432.SCE1572_42235	7.133e-218	699.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria,1R5BE@1224|Proteobacteria,4339F@68525|delta/epsilon subdivisions,2WYFR@28221|Deltaproteobacteria,2YTXM@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of Unknown Function with PDB structure (DUF3857)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19,TPR_8,Transglut_core
SHD3_k127_4765617_3	247639.MGP2080_05877	1.069e-36	144.0	COG2311@1|root,COG2311@2|Bacteria,1MWHW@1224|Proteobacteria,1RQ08@1236|Gammaproteobacteria,1J70N@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF418
SHD3_k127_4765617_2	401053.AciPR4_0158	6.543e-66	243.0	COG0612@1|root,COG0612@2|Bacteria,3Y2UB@57723|Acidobacteria,2JITC@204432|Acidobacteriia	204432|Acidobacteriia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_4765617_1	29581.BW37_00307	2.064e-124	417.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,472VG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_4765617_0	215803.DB30_5241	0.0	1395.0	COG0642@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C0N@68525|delta/epsilon subdivisions,2X7B9@28221|Deltaproteobacteria,2Z3EZ@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
SHD3_k127_4765617_4	1192034.CAP_0867	1.173e-10	70.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X6Z3@28221|Deltaproteobacteria,2YWFG@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat
SHD3_k127_477331_5	391625.PPSIR1_18632	5.266e-42	161.0	COG5297@1|root,COG5297@2|Bacteria,1NDMY@1224|Proteobacteria,4333K@68525|delta/epsilon subdivisions,2WXH7@28221|Deltaproteobacteria,2YXQH@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,CelD_N,Glyco_hydro_9
SHD3_k127_477331_3	1254432.SCE1572_41670	2.968e-61	224.0	COG3016@1|root,COG3016@2|Bacteria,1MX1I@1224|Proteobacteria,42U2R@68525|delta/epsilon subdivisions,2WM9S@28221|Deltaproteobacteria,2YZVS@29|Myxococcales	28221|Deltaproteobacteria	S	Haem-binding uptake, Tiki superfamily, ChaN	-	-	-	-	-	-	-	-	-	-	-	-	Cofac_haem_bdg,PDZ_2
SHD3_k127_477331_8	765420.OSCT_0225	2.6e-05	53.0	COG1719@1|root,COG1719@2|Bacteria	2|Bacteria	KT	4-vinyl reductase, 4VR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,HTH_8,Sigma54_activat,V4R,XylR_N
SHD3_k127_477331_4	1089553.Tph_c27930	3.924e-57	209.0	COG0467@1|root,COG0467@2|Bacteria,1V05P@1239|Firmicutes,24ED2@186801|Clostridia	186801|Clostridia	T	Pfam:KaiC	-	-	-	-	-	-	-	-	-	-	-	-	ATPase
SHD3_k127_477331_2	1242864.D187_005156	9.464e-101	346.0	COG0467@1|root,COG0467@2|Bacteria,1NM7E@1224|Proteobacteria,42SM2@68525|delta/epsilon subdivisions,2WPEU@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SHD3_k127_477331_7	1337936.IJ00_01030	2.89e-06	59.0	2DN63@1|root,32VRT@2|Bacteria,1G831@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_477331_0	1198114.AciX9_2547	7.55e-125	424.0	COG0467@1|root,COG0467@2|Bacteria,3Y6QG@57723|Acidobacteria,2JM7Y@204432|Acidobacteriia	204432|Acidobacteriia	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SHD3_k127_477331_1	290397.Adeh_3529	8.787e-122	418.0	COG0642@1|root,COG0784@1|root,COG2461@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,43CCU@68525|delta/epsilon subdivisions,2X7NQ@28221|Deltaproteobacteria,2YX99@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_477331_6	530564.Psta_1465	2.464e-30	135.0	COG0699@1|root,COG0699@2|Bacteria	2|Bacteria	T	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SHD3_k127_4774744_0	1192034.CAP_7046	1.35e-47	185.0	COG3628@1|root,COG3628@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4774744_2	448385.sce4032	4.976e-11	74.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_478116_1	656519.Halsa_2243	1.005e-39	162.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3WAAI@53433|Halanaerobiales	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SHD3_k127_478116_2	1131269.AQVV01000013_gene1770	5.495e-24	115.0	COG0053@1|root,COG0053@2|Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
SHD3_k127_478116_4	156889.Mmc1_2267	8.721e-06	57.0	COG0265@1|root,COG0265@2|Bacteria,1NTJ8@1224|Proteobacteria	1224|Proteobacteria	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SHD3_k127_478116_3	1121015.N789_10520	2.063e-06	58.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,1RN9T@1236|Gammaproteobacteria,1X3EN@135614|Xanthomonadales	135614|Xanthomonadales	O	Belongs to the peptidase S1C family	htrA	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ,PDZ_2,Trypsin_2
SHD3_k127_478116_0	1380394.JADL01000010_gene4355	1.027e-48	189.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,2TQPZ@28211|Alphaproteobacteria,2JQVG@204441|Rhodospirillales	204441|Rhodospirillales	O	Belongs to the peptidase S1C family	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_4797385_3	1254432.SCE1572_29260	5.989e-78	277.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
SHD3_k127_4797385_2	1254432.SCE1572_29265	9.52e-148	497.0	COG4206@1|root,COG4206@2|Bacteria,1QTTF@1224|Proteobacteria,43CUK@68525|delta/epsilon subdivisions,2X828@28221|Deltaproteobacteria	1224|Proteobacteria	H	Outer membrane receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
SHD3_k127_4797385_6	448385.sce0781	2.674e-24	108.0	COG0835@1|root,COG0835@2|Bacteria	2|Bacteria	NT	chemotaxis	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SHD3_k127_4797385_7	1254432.SCE1572_05490	1.832e-23	109.0	COG2199@1|root,COG3706@2|Bacteria	2|Bacteria	T	GGDEF domain	-	-	2.7.7.65	ko:K02488,ko:K21025	ko02020,ko02025,ko04112,map02020,map02025,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	EAL,GGDEF,HATPase_c,Response_reg
SHD3_k127_4797385_1	1254432.SCE1572_05475	2.885e-184	589.0	COG0840@1|root,COG3290@1|root,COG0840@2|Bacteria,COG3290@2|Bacteria,1MU9B@1224|Proteobacteria,42R36@68525|delta/epsilon subdivisions,2WU0Z@28221|Deltaproteobacteria,2YZN9@29|Myxococcales	28221|Deltaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	frzCD	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_4,PAS_9,dCache_1,sCache_3_2,sCache_3_3
SHD3_k127_4797385_0	1254432.SCE1572_05470	1.502e-235	749.0	COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,1MUAG@1224|Proteobacteria,439YY@68525|delta/epsilon subdivisions,2X1I2@28221|Deltaproteobacteria,2YW92@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	cheA3	-	2.7.13.3	ko:K03407,ko:K13490	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00509	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
SHD3_k127_4797385_4	1254432.SCE1572_05465	5.126e-77	271.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2WJ2S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SHD3_k127_4797385_8	1254432.SCE1572_05460	7.874e-18	86.0	COG0457@1|root,COG1352@1|root,COG0457@2|Bacteria,COG1352@2|Bacteria	2|Bacteria	NT	protein-glutamate O-methyltransferase activity	wspC	-	2.1.1.80	ko:K00575,ko:K13486	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,TPR_8
SHD3_k127_480932_0	269799.Gmet_1424	1.067e-195	649.0	COG0249@1|root,COG0249@2|Bacteria,1MUGX@1224|Proteobacteria,42MRR@68525|delta/epsilon subdivisions,2WIQ7@28221|Deltaproteobacteria,43TPJ@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
SHD3_k127_480932_2	448385.sce3023	1.327e-21	103.0	2BQRM@1|root,32JN9@2|Bacteria,1PDHV@1224|Proteobacteria,435GS@68525|delta/epsilon subdivisions,2WZUA@28221|Deltaproteobacteria,2Z2RV@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4826842_3	96561.Dole_3110	5.788e-46	181.0	COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,42TW3@68525|delta/epsilon subdivisions,2WPZS@28221|Deltaproteobacteria,2MKHQ@213118|Desulfobacterales	28221|Deltaproteobacteria	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
SHD3_k127_4826842_1	330214.NIDE0446	1.057e-81	282.0	COG0169@1|root,COG0169@2|Bacteria,3J0SM@40117|Nitrospirae	40117|Nitrospirae	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
SHD3_k127_4826842_4	237609.PSAKL28_39850	4.06e-28	132.0	COG0349@1|root,COG0349@2|Bacteria,1MURV@1224|Proteobacteria,1RPBP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	J	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides	rnd	GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0033890,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
SHD3_k127_4826842_2	387093.SUN_1308	9.441e-80	275.0	COG1409@1|root,COG1409@2|Bacteria,1MXD6@1224|Proteobacteria,42SIA@68525|delta/epsilon subdivisions,2YREF@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
SHD3_k127_4826842_0	1192034.CAP_8571	1.098e-144	468.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,PD40,Peptidase_S9
SHD3_k127_4826842_5	502025.Hoch_6345	8.126e-22	105.0	COG1309@1|root,COG1309@2|Bacteria,1NDYG@1224|Proteobacteria,42WJ9@68525|delta/epsilon subdivisions,2X293@28221|Deltaproteobacteria,2YZAR@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_4835713_14	10224.XP_002740083.1	2.137e-07	58.0	COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BDZ9@33208|Metazoa,3CW1H@33213|Bilateria	33208|Metazoa	S	Transmembrane and TPR repeat-containing protein	TMTC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827	-	-	-	-	-	-	-	-	-	-	DUF1736,TPR_1,TPR_16,TPR_2,TPR_8
SHD3_k127_4835713_13	1123248.KB893314_gene3436	1.248e-07	61.0	COG1704@1|root,COG1704@2|Bacteria,4NMD3@976|Bacteroidetes,1IS2G@117747|Sphingobacteriia	976|Bacteroidetes	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
SHD3_k127_4835713_8	156889.Mmc1_2254	1.094e-32	143.0	COG0265@1|root,COG0265@2|Bacteria,1NZFR@1224|Proteobacteria,2USTQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4835713_11	644968.DFW101_3511	6.892e-13	71.0	2AE4W@1|root,313Y7@2|Bacteria,1PT9D@1224|Proteobacteria,4335W@68525|delta/epsilon subdivisions,2WXPB@28221|Deltaproteobacteria,2ME2H@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4835713_6	1242864.D187_006022	3.483e-48	183.0	COG3118@1|root,COG3118@2|Bacteria,1RJYC@1224|Proteobacteria,435D0@68525|delta/epsilon subdivisions,2WZQM@28221|Deltaproteobacteria,2Z2IT@29|Myxococcales	28221|Deltaproteobacteria	O	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
SHD3_k127_4835713_2	1242864.D187_006023	1.23e-105	359.0	COG0501@1|root,COG0501@2|Bacteria,1NG7Y@1224|Proteobacteria,434VJ@68525|delta/epsilon subdivisions,2X91I@28221|Deltaproteobacteria,2Z1FS@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
SHD3_k127_4835713_9	35754.JNYJ01000036_gene3658	6.038e-23	109.0	COG0515@1|root,COG0515@2|Bacteria,2GMPZ@201174|Actinobacteria,4DDFA@85008|Micromonosporales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4835713_7	335543.Sfum_1291	1.105e-41	156.0	COG1959@1|root,COG1959@2|Bacteria,1PC6N@1224|Proteobacteria,43EVM@68525|delta/epsilon subdivisions,2X9SC@28221|Deltaproteobacteria,2MSFF@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
SHD3_k127_4835713_3	269796.Rru_A1066	2.815e-101	343.0	COG1136@1|root,COG1136@2|Bacteria,1PXKV@1224|Proteobacteria,2U2EP@28211|Alphaproteobacteria,2JWPD@204441|Rhodospirillales	204441|Rhodospirillales	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SHD3_k127_4835713_1	269796.Rru_A1067	4.762e-118	383.0	COG0378@1|root,COG0378@2|Bacteria	2|Bacteria	KO	nickel cation binding	-	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
SHD3_k127_4835713_4	1150469.RSPPHO_02568	2.9e-92	307.0	COG2000@1|root,COG2000@2|Bacteria,1NU4F@1224|Proteobacteria	1224|Proteobacteria	C	Putative Fe-S cluster	-	-	-	-	-	-	-	-	-	-	-	-	FeS
SHD3_k127_4835713_12	485913.Krac_1616	1.074e-09	70.0	2F8X7@1|root,34192@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4835713_0	448385.sce5848	3.273e-140	474.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_4835713_15	929703.KE386491_gene2805	1.204e-06	60.0	2CIB5@1|root,334EI@2|Bacteria,4NWSN@976|Bacteroidetes,47W2Y@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4835713_16	765420.OSCT_0866	0.0007536	51.0	2A48D@1|root,30STK@2|Bacteria,2GAP6@200795|Chloroflexi,376XA@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4835713_10	322710.Avin_16000	7.266e-15	88.0	28HDP@1|root,2Z7Q8@2|Bacteria,1MXR8@1224|Proteobacteria,1S3FG@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4835713_5	243231.GSU0626	3.689e-62	215.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,42KZY@68525|delta/epsilon subdivisions,2WJ4B@28221|Deltaproteobacteria,43T4M@69541|Desulfuromonadales	28221|Deltaproteobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SHD3_k127_483798_12	1254432.SCE1572_44005	1.438e-35	138.0	COG0218@1|root,COG0218@2|Bacteria,1MY3Z@1224|Proteobacteria,42RJR@68525|delta/epsilon subdivisions,2WMK3@28221|Deltaproteobacteria,2YVG8@29|Myxococcales	28221|Deltaproteobacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
SHD3_k127_483798_9	1192034.CAP_7143	9.647e-51	188.0	COG1381@1|root,COG1381@2|Bacteria,1RIBW@1224|Proteobacteria,42PUE@68525|delta/epsilon subdivisions,2WK4W@28221|Deltaproteobacteria,2YVXU@29|Myxococcales	28221|Deltaproteobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
SHD3_k127_483798_7	1254432.SCE1572_10575	6.068e-54	192.0	COG1426@1|root,COG1426@2|Bacteria,1NIQS@1224|Proteobacteria,4387Z@68525|delta/epsilon subdivisions,2X3HR@28221|Deltaproteobacteria,2YW5H@29|Myxococcales	28221|Deltaproteobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_25
SHD3_k127_483798_4	1192034.CAP_7145	3.743e-75	262.0	COG0457@1|root,COG0457@2|Bacteria,1MZGK@1224|Proteobacteria,42US4@68525|delta/epsilon subdivisions,2X72T@28221|Deltaproteobacteria,2YVP7@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_6,TPR_8
SHD3_k127_483798_5	1254432.SCE1572_10565	1.234e-74	258.0	COG0664@1|root,COG0664@2|Bacteria,1NHNS@1224|Proteobacteria,42X3Y@68525|delta/epsilon subdivisions,2WT4M@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	cyclic nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
SHD3_k127_483798_14	1120965.AUBV01000008_gene1889	1.001e-22	111.0	COG1214@1|root,COG1214@2|Bacteria,4NDUR@976|Bacteroidetes,47NST@768503|Cytophagia	976|Bacteroidetes	O	TIGRFAM universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
SHD3_k127_483798_2	1254432.SCE1572_17475	4.478e-101	343.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1MVE7@1224|Proteobacteria,43AG6@68525|delta/epsilon subdivisions,2X63V@28221|Deltaproteobacteria,2Z0GY@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SHD3_k127_483798_18	1123277.KB893241_gene5283	0.0005371	47.0	COG1577@1|root,COG3391@1|root,COG1577@2|Bacteria,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	mvaK2	-	2.7.1.36,2.7.4.2	ko:K00869,ko:K00938,ko:K20276	ko00900,ko01100,ko01110,ko01130,ko02024,ko04146,map00900,map01100,map01110,map01130,map02024,map04146	M00095	R02245,R03245	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N,VCBS
SHD3_k127_483798_1	96561.Dole_1480	1.522e-145	482.0	COG1032@1|root,COG1032@2|Bacteria,1RJ9Z@1224|Proteobacteria,42TDD@68525|delta/epsilon subdivisions,2WPHS@28221|Deltaproteobacteria,2MK5Y@213118|Desulfobacterales	28221|Deltaproteobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K22318	-	-	-	-	ko00000	-	-	-	Radical_SAM
SHD3_k127_483798_15	1283300.ATXB01000001_gene891	4.749e-21	103.0	COG1191@1|root,COG1191@2|Bacteria,1MWEU@1224|Proteobacteria,1RMKJ@1236|Gammaproteobacteria,1XEDJ@135618|Methylococcales	135618|Methylococcales	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes	fliA	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
SHD3_k127_483798_6	443144.GM21_0360	1.141e-60	218.0	COG2199@1|root,COG3706@2|Bacteria,1QWNG@1224|Proteobacteria,42SDQ@68525|delta/epsilon subdivisions,2WP1N@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc,Response_reg
SHD3_k127_483798_3	665571.STHERM_c05640	4.195e-98	345.0	COG0642@1|root,COG2205@2|Bacteria,2J6U2@203691|Spirochaetes	203691|Spirochaetes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,HATPase_c,HisKA,Hpt,PAS_4,PAS_9,Reg_prop,Response_reg,dCache_1
SHD3_k127_483798_11	1356852.N008_09475	2.888e-36	147.0	2D6MI@1|root,32TMJ@2|Bacteria,4NPMS@976|Bacteroidetes,47Q9V@768503|Cytophagia	976|Bacteroidetes	S	PAP2 superfamily C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_C
SHD3_k127_483798_0	631362.Thi970DRAFT_04011	1.07e-181	597.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1MV6M@1224|Proteobacteria,1RQ34@1236|Gammaproteobacteria,1WWR1@135613|Chromatiales	135613|Chromatiales	KL	DNA RNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N,SWIM
SHD3_k127_483798_16	7370.XP_005190497.1	4.819e-09	68.0	KOG3948@1|root,KOG3948@2759|Eukaryota,38CJ2@33154|Opisthokonta,3BIGQ@33208|Metazoa,3D2WG@33213|Bilateria,41Z5P@6656|Arthropoda,3SMFY@50557|Insecta,451H9@7147|Diptera	33208|Metazoa	A	PHAX RNA-binding domain	PHAX	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006351,GO:0006366,GO:0006403,GO:0006405,GO:0006408,GO:0006725,GO:0006807,GO:0006810,GO:0006913,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009301,GO:0009987,GO:0010467,GO:0015630,GO:0015643,GO:0015931,GO:0016070,GO:0016073,GO:0018130,GO:0019438,GO:0031974,GO:0031981,GO:0032774,GO:0033036,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0036477,GO:0042795,GO:0043025,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046907,GO:0050657,GO:0050658,GO:0051030,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051641,GO:0051649,GO:0070013,GO:0071702,GO:0071704,GO:0071705,GO:0090304,GO:0097064,GO:0097159,GO:0097458,GO:0097659,GO:0098781,GO:1901360,GO:1901362,GO:1901363,GO:1901576	-	ko:K14291	ko03013,map03013	-	-	-	ko00000,ko00001	-	-	-	RNA_GG_bind
SHD3_k127_483798_8	290397.Adeh_0453	3.344e-51	189.0	COG0500@1|root,COG0500@2|Bacteria,1R947@1224|Proteobacteria,432GY@68525|delta/epsilon subdivisions,2WYII@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_483798_10	1254432.SCE1572_10090	1.25e-36	153.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4840101_3	1232683.ADIMK_1231	4.728e-111	367.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,1RMV1@1236|Gammaproteobacteria,464Z8@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	COG4992 Ornithine acetylornithine aminotransferase	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SHD3_k127_4840101_5	1123487.KB892865_gene1453	1.267e-91	316.0	COG3174@1|root,COG3174@2|Bacteria,1NDBI@1224|Proteobacteria,2VJ4P@28216|Betaproteobacteria,2KUDC@206389|Rhodocyclales	206389|Rhodocyclales	S	Domain of unknown function (DUF4010)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4010,MgtC
SHD3_k127_4840101_8	946483.Cenrod_0412	5.417e-05	53.0	COG1451@1|root,COG1451@2|Bacteria,1MXZU@1224|Proteobacteria,2VNC5@28216|Betaproteobacteria,4A9K3@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
SHD3_k127_4840101_6	670487.Ocepr_0569	2.215e-22	112.0	COG0204@1|root,COG0204@2|Bacteria,1WJXG@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	PFAM Phospholipid glycerol acyltransferase	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
SHD3_k127_4840101_2	357808.RoseRS_0975	1.485e-129	422.0	COG0309@1|root,COG0309@2|Bacteria,2G5MV@200795|Chloroflexi,376G0@32061|Chloroflexia	32061|Chloroflexia	O	TIGRFAM hydrogenase expression formation protein HypE	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
SHD3_k127_4840101_1	518766.Rmar_2595	2.517e-162	518.0	COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes	976|Bacteroidetes	O	TIGRFAM hydrogenase expression formation protein HypD	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
SHD3_k127_4840101_7	1541065.JRFE01000006_gene4850	2.359e-21	95.0	COG0298@1|root,COG0298@2|Bacteria,1G9FZ@1117|Cyanobacteria,3VKNN@52604|Pleurocapsales	1117|Cyanobacteria	O	TIGRFAM hydrogenase assembly chaperone hypC hupF	hypC	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
SHD3_k127_4840101_0	926550.CLDAP_07460	1.279e-263	832.0	COG0068@1|root,COG0068@2|Bacteria,2G5QN@200795|Chloroflexi	200795|Chloroflexi	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
SHD3_k127_4840101_4	1121935.AQXX01000131_gene2856	3.661e-100	336.0	COG4989@1|root,COG4989@2|Bacteria,1MY3G@1224|Proteobacteria,1RRIC@1236|Gammaproteobacteria,1XK55@135619|Oceanospirillales	135619|Oceanospirillales	S	Aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SHD3_k127_4851072_2	1254432.SCE1572_37305	4.204e-76	263.0	COG0575@1|root,COG0575@2|Bacteria,1MWSV@1224|Proteobacteria,42U86@68525|delta/epsilon subdivisions,2WPKR@28221|Deltaproteobacteria,2Z3NC@29|Myxococcales	28221|Deltaproteobacteria	I	Cytidylyltransferase family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
SHD3_k127_4851072_6	448385.sce8901	4.702e-35	141.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_4851072_12	448385.sce3319	2.282e-08	67.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_4851072_3	1242864.D187_004294	3.128e-61	222.0	COG1073@1|root,COG1073@2|Bacteria,1RIWI@1224|Proteobacteria,42TGK@68525|delta/epsilon subdivisions,2WRBS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha/beta hydrolase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
SHD3_k127_4851072_13	1254432.SCE1572_03625	1.65e-06	57.0	COG3391@1|root,COG3591@1|root,COG3391@2|Bacteria,COG3591@2|Bacteria,1R0BE@1224|Proteobacteria,43CTP@68525|delta/epsilon subdivisions,2X817@28221|Deltaproteobacteria,2Z05E@29|Myxococcales	28221|Deltaproteobacteria	E	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_4851072_1	448385.sce2904	9.96e-115	386.0	2AIWV@1|root,319EH@2|Bacteria,1Q2HT@1224|Proteobacteria,433TN@68525|delta/epsilon subdivisions,2X3EP@28221|Deltaproteobacteria,2YVQT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4851072_0	1192034.CAP_0163	1.26e-128	422.0	COG3303@1|root,COG3303@2|Bacteria,1MYBV@1224|Proteobacteria,42SER@68525|delta/epsilon subdivisions,2WPC2@28221|Deltaproteobacteria,2YUR5@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
SHD3_k127_4851072_7	1254432.SCE1572_17705	1.035e-32	129.0	2BGQS@1|root,32APS@2|Bacteria,1QAWR@1224|Proteobacteria,43E4J@68525|delta/epsilon subdivisions,2X97X@28221|Deltaproteobacteria,2Z2HF@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4851072_9	706587.Desti_0293	1.509e-28	131.0	COG1633@1|root,COG1633@2|Bacteria,1N4PW@1224|Proteobacteria,42UZG@68525|delta/epsilon subdivisions,2WNGQ@28221|Deltaproteobacteria,2MS9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	S	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SHD3_k127_4851072_4	765952.PUV_25710	2.308e-57	222.0	COG0477@1|root,COG2814@2|Bacteria,2JFUR@204428|Chlamydiae	204428|Chlamydiae	EGP	Major Facilitator Superfamily	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	MFS_1
SHD3_k127_4851072_8	397945.Aave_1288	2.124e-31	127.0	COG0463@1|root,COG0463@2|Bacteria,1P8G7@1224|Proteobacteria,2VTB4@28216|Betaproteobacteria	28216|Betaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_4868130_1	1499967.BAYZ01000108_gene2206	2.438e-88	314.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
SHD3_k127_4868130_0	1192034.CAP_3357	3.913e-119	401.0	COG0515@1|root,COG0515@2|Bacteria,1Q38J@1224|Proteobacteria,438ZJ@68525|delta/epsilon subdivisions,2X44T@28221|Deltaproteobacteria,2YY98@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	masK	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_4868130_2	1192034.CAP_0383	3.808e-19	96.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SHD3_k127_48792_5	1123508.JH636443_gene4639	2.614e-09	65.0	COG1005@1|root,COG1005@2|Bacteria,2IXH1@203682|Planctomycetes	203682|Planctomycetes	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
SHD3_k127_48792_0	1120950.KB892708_gene4380	0.0	1046.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4DPKG@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	-	ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
SHD3_k127_48792_2	448385.sce7249	1.122e-106	351.0	COG1100@1|root,COG1100@2|Bacteria,1R6NS@1224|Proteobacteria,42NIX@68525|delta/epsilon subdivisions,2WJ44@28221|Deltaproteobacteria,2YU2F@29|Myxococcales	28221|Deltaproteobacteria	S	ADP-ribosylation factor family	mglA	GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007	-	ko:K06883	-	-	-	-	ko00000	-	-	-	Arf,Ras
SHD3_k127_48792_1	1254432.SCE1572_11645	2.092e-135	458.0	COG1629@1|root,COG4771@2|Bacteria,1QX4E@1224|Proteobacteria,437VM@68525|delta/epsilon subdivisions,2X358@28221|Deltaproteobacteria,2YUBU@29|Myxococcales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_C,TonB_dep_Rec
SHD3_k127_48792_6	877415.JNJQ01000009_gene990	1.109e-06	61.0	COG4225@1|root,COG4225@2|Bacteria,1TRJ7@1239|Firmicutes,3VSVN@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
SHD3_k127_4881132_2	290397.Adeh_0078	2.839e-19	91.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4881132_0	1254432.SCE1572_25675	0.0	1465.0	COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,42MKB@68525|delta/epsilon subdivisions,2WJ4W@28221|Deltaproteobacteria,2YUFE@29|Myxococcales	28221|Deltaproteobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
SHD3_k127_4881132_1	1254432.SCE1572_18910	2.917e-86	296.0	COG0726@1|root,COG0726@2|Bacteria,1MWYU@1224|Proteobacteria,4317N@68525|delta/epsilon subdivisions,2WWU5@28221|Deltaproteobacteria,2YV2P@29|Myxococcales	28221|Deltaproteobacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
SHD3_k127_4884527_0	452637.Oter_1744	6.696e-165	524.0	COG3459@1|root,COG3459@2|Bacteria,46TCU@74201|Verrucomicrobia	2|Bacteria	H	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
SHD3_k127_4884527_1	765420.OSCT_1871	1.421e-121	400.0	COG0483@1|root,COG0483@2|Bacteria,2G88V@200795|Chloroflexi	200795|Chloroflexi	G	inositol monophosphate 1-phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4884527_2	394503.Ccel_2001	1.778e-113	387.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,36F99@31979|Clostridiaceae	186801|Clostridia	P	transporter	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SHD3_k127_4884527_3	1434929.X946_2479	5.69e-21	94.0	COG2350@1|root,COG2350@2|Bacteria	2|Bacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
SHD3_k127_4884527_4	404589.Anae109_3673	3.668e-17	84.0	COG1396@1|root,COG1396@2|Bacteria,1NMZH@1224|Proteobacteria	1224|Proteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_37
SHD3_k127_4896508_4	525904.Tter_0313	5.375e-39	150.0	COG0137@1|root,COG0137@2|Bacteria,2NR2I@2323|unclassified Bacteria	2|Bacteria	E	Arginosuccinate synthase	-	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
SHD3_k127_4896508_0	483219.LILAB_20000	1.889e-147	489.0	COG4789@1|root,COG4789@2|Bacteria,1R346@1224|Proteobacteria,43DIZ@68525|delta/epsilon subdivisions,2X8Q9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	U	Type III secretion protein	-	-	-	ko:K03230	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	FHIPEP
SHD3_k127_4896508_3	448385.sce6951	3.247e-64	234.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
SHD3_k127_4896508_1	1254432.SCE1572_40870	5.163e-99	329.0	COG0631@1|root,COG0631@2|Bacteria,1R7UF@1224|Proteobacteria,439RM@68525|delta/epsilon subdivisions,2X54F@28221|Deltaproteobacteria,2Z03P@29|Myxococcales	28221|Deltaproteobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
SHD3_k127_4896508_2	1254432.SCE1572_40305	6.64e-95	316.0	COG1181@1|root,COG1181@2|Bacteria,1MUTB@1224|Proteobacteria,42NF2@68525|delta/epsilon subdivisions,2WJ7Q@28221|Deltaproteobacteria,2YUFD@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
SHD3_k127_4907660_0	448385.sce2937	2.868e-259	832.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce2937|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4907660_1	1254432.SCE1572_39085	5.345e-195	620.0	COG0112@1|root,COG0112@2|Bacteria,1MUIS@1224|Proteobacteria,42M0T@68525|delta/epsilon subdivisions,2WJ3C@28221|Deltaproteobacteria,2YTTC@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SHD3_k127_4907660_2	84751.XP_007882496.1	3.994e-09	68.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38DMI@33154|Opisthokonta,3PF4P@4751|Fungi,3V643@5204|Basidiomycota	4751|Fungi	T	Si dkey-21a6.5	-	-	-	-	-	-	-	-	-	-	-	-	Ephrin_rec_like
SHD3_k127_4915950_1	1242864.D187_002335	4.43e-32	139.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNJE@28221|Deltaproteobacteria,2Z1RI@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SHD3_k127_4915950_2	1242864.D187_007221	2.759e-24	121.0	COG0515@1|root,COG0515@2|Bacteria	1242864.D187_007221|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4915950_8	324602.Caur_0662	7.014e-05	57.0	2DSCK@1|root,32USS@2|Bacteria,2GAKK@200795|Chloroflexi,376NF@32061|Chloroflexia	32061|Chloroflexia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4915950_4	1254432.SCE1572_05290	9.952e-20	106.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_binding_2,FTP,FlgD_ig,PPC,Peptidase_M4,Peptidase_M4_C,RicinB_lectin_2,SBBP,TIG,Trypsin,VCBS
SHD3_k127_4915950_9	1246995.AFR_35245	0.0001998	54.0	COG1520@1|root,COG1520@2|Bacteria,2ISHY@201174|Actinobacteria,4DF7R@85008|Micromonosporales	201174|Actinobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SHD3_k127_4915950_7	378806.STAUR_2410	4.396e-08	65.0	COG1961@1|root,COG1961@2|Bacteria,1MWCZ@1224|Proteobacteria,42PDG@68525|delta/epsilon subdivisions,2WKNJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Resolvase	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
SHD3_k127_4915950_3	1254432.SCE1572_34570	1.886e-23	106.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
SHD3_k127_4915950_5	641112.ACOK01000059_gene186	7.556e-18	94.0	COG2382@1|root,COG3693@1|root,COG2382@2|Bacteria,COG3693@2|Bacteria,1V05A@1239|Firmicutes,24HZA@186801|Clostridia,3WNWK@541000|Ruminococcaceae	186801|Clostridia	GP	Glycosyl hydrolases family 11	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Esterase,Glyco_hydro_11
SHD3_k127_4915950_0	502025.Hoch_2959	3.986e-36	141.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SHD3_k127_4917131_5	515635.Dtur_0727	5.864e-49	194.0	COG0457@1|root,COG1305@1|root,COG0457@2|Bacteria,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,Transglut_core
SHD3_k127_4917131_0	448385.sce7186	0.0	1055.0	COG0457@1|root,COG0457@2|Bacteria,1Q2H1@1224|Proteobacteria,4383J@68525|delta/epsilon subdivisions,2X3DM@28221|Deltaproteobacteria,2YVKC@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,TPR_16,TPR_19
SHD3_k127_4917131_18	1041607.K0KH04	3.731e-06	59.0	COG0664@1|root,KOG1113@2759|Eukaryota,38GS1@33154|Opisthokonta,3NU9Z@4751|Fungi,3QKI5@4890|Ascomycota,3RSCY@4891|Saccharomycetes	4751|Fungi	T	cAMP-dependent protein kinase regulatory subunit	PKAR	GO:0000003,GO:0000166,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0005952,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008277,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030551,GO:0030552,GO:0030554,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0043949,GO:0043951,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045744,GO:0045761,GO:0045762,GO:0045786,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051445,GO:0051447,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097159,GO:0097271,GO:0097367,GO:0098772,GO:0106070,GO:0106072,GO:0110033,GO:0110034,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1901265,GO:1901363,GO:1902531,GO:1902532,GO:1902659,GO:1902660,GO:1903664,GO:1903666,GO:1903827,GO:1903829,GO:1904951,GO:2000241,GO:2000242,GO:2000479,GO:2000480	-	ko:K04739	ko04910,map04910	-	-	-	ko00000,ko00001	-	-	-	RIIa,cNMP_binding
SHD3_k127_4917131_15	1051632.TPY_1662	1.634e-11	76.0	COG0477@1|root,COG2814@2|Bacteria,1UN4X@1239|Firmicutes,25GWF@186801|Clostridia,3WDNP@538999|Clostridiales incertae sedis	2|Bacteria	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,MFS_3
SHD3_k127_4917131_2	1121957.ATVL01000006_gene2934	1.131e-87	300.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	phoA	-	3.1.3.2	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	-	R00548	RC00017	ko00000,ko00001,ko01000	-	-	-	Metallophos,PQQ_2,PQQ_3
SHD3_k127_4917131_9	1463920.JOGB01000040_gene4162	3.526e-37	148.0	2F1NT@1|root,33UP3@2|Bacteria,2IG09@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4917131_19	913865.DOT_1025	2.642e-05	56.0	29JY6@1|root,306VF@2|Bacteria,1UTWY@1239|Firmicutes,254PX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4917131_12	448385.sce1487	2.775e-20	101.0	COG0457@1|root,COG0457@2|Bacteria,1QB30@1224|Proteobacteria,43E53@68525|delta/epsilon subdivisions,2WZRF@28221|Deltaproteobacteria,2Z2KD@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4917131_10	1254432.SCE1572_09715	6.855e-36	145.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_4917131_1	215803.DB30_3649	6.871e-121	400.0	COG2220@1|root,COG2220@2|Bacteria,1MV20@1224|Proteobacteria,42QPP@68525|delta/epsilon subdivisions,2WK2U@28221|Deltaproteobacteria,2YTUH@29|Myxococcales	28221|Deltaproteobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
SHD3_k127_4917131_8	1220534.B655_0672	8.817e-43	177.0	arCOG01788@1|root,arCOG01788@2157|Archaea	2157|Archaea	S	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_4917131_3	665571.STHERM_c17700	7.973e-54	202.0	COG0508@1|root,COG0508@2|Bacteria,2J5U3@203691|Spirochaetes	203691|Spirochaetes	C	dehydrogenase complex catalyzes the overall conversion of	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh
SHD3_k127_4917131_7	1035308.AQYY01000001_gene3504	1.679e-46	175.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,2608N@186807|Peptococcaceae	186801|Clostridia	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	2.3.1.40,6.2.1.20,6.2.1.3,6.2.1.48	ko:K01897,ko:K02182,ko:K05939	ko00061,ko00071,ko00564,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00564,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280,R01406,R04864	RC00004,RC00014,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
SHD3_k127_4917131_13	502025.Hoch_5370	1.129e-18	89.0	COG4775@1|root,COG4775@2|Bacteria,1RDM0@1224|Proteobacteria,42S2Q@68525|delta/epsilon subdivisions,2WNSG@28221|Deltaproteobacteria,2YX6N@29|Myxococcales	28221|Deltaproteobacteria	M	Surface antigen	-	-	-	-	-	-	-	-	-	-	-	-	Bac_surface_Ag
SHD3_k127_4917131_4	1192034.CAP_2110	1.14e-51	194.0	COG0454@1|root,COG0456@2|Bacteria,1PC8S@1224|Proteobacteria,438AY@68525|delta/epsilon subdivisions,2X1TU@28221|Deltaproteobacteria,2YWEB@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SHD3_k127_4917131_11	1192034.CAP_6604	3.676e-28	126.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_4917131_6	448385.sce5929	6.042e-47	180.0	2DSD6@1|root,33FM0@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4917131_14	760154.Sulba_1350	1.603e-14	84.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2YTMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_4925769_11	1242864.D187_003567	7.262e-18	85.0	COG0326@1|root,COG0326@2|Bacteria,1MUUE@1224|Proteobacteria,42N42@68525|delta/epsilon subdivisions,2WK62@28221|Deltaproteobacteria,2YWZ7@29|Myxococcales	28221|Deltaproteobacteria	O	Molecular chaperone. Has ATPase activity	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
SHD3_k127_4925769_10	448385.sce1083	1.214e-18	89.0	2ANPU@1|root,31DPC@2|Bacteria,1QB0N@1224|Proteobacteria,435DB@68525|delta/epsilon subdivisions,2WZQX@28221|Deltaproteobacteria,2Z2JD@29|Myxococcales	28221|Deltaproteobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SHD3_k127_4925769_12	330084.JNYZ01000020_gene4595	1.49e-08	66.0	COG5640@1|root,COG5640@2|Bacteria,2I97B@201174|Actinobacteria	201174|Actinobacteria	O	Trypsin-like serine protease	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin
SHD3_k127_4925769_5	391625.PPSIR1_05378	6.711e-93	323.0	COG3405@1|root,COG3405@2|Bacteria,1N41Q@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_8
SHD3_k127_4925769_8	867903.ThesuDRAFT_01594	5.358e-58	218.0	COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,248M5@186801|Clostridia	186801|Clostridia	C	TIGRFAM iron-sulfur cluster binding protein	queG	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16,HEAT_2
SHD3_k127_4925769_3	1254432.SCE1572_27045	1.333e-114	377.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2YUM7@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_4925769_7	448385.sce4422	2.037e-67	250.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,437H5@68525|delta/epsilon subdivisions,2X2QG@28221|Deltaproteobacteria,2YUX3@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SHD3_k127_4925769_0	448385.sce4423	3.306e-162	539.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,437Y9@68525|delta/epsilon subdivisions,2X9RZ@28221|Deltaproteobacteria,2YUSF@29|Myxococcales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
SHD3_k127_4925769_6	448385.sce4424	6.967e-82	286.0	2A45R@1|root,30SQS@2|Bacteria,1PC2Q@1224|Proteobacteria,4387Q@68525|delta/epsilon subdivisions,2X3HH@28221|Deltaproteobacteria,2YW4R@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
SHD3_k127_4925769_4	448385.sce3929	3.673e-97	342.0	COG3119@1|root,COG3119@2|Bacteria,1QZHU@1224|Proteobacteria,42PUM@68525|delta/epsilon subdivisions,2X7T5@28221|Deltaproteobacteria,2Z00V@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	3.1.6.6	ko:K01133	-	-	-	-	ko00000,ko01000	-	-	-	Cu-binding_MopE,Sulfatase
SHD3_k127_4925769_1	1254432.SCE1572_17165	2.81e-158	515.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SHD3_k127_4925769_14	670292.JH26_28335	0.0006012	50.0	2AQC4@1|root,31FIA@2|Bacteria,1RIJR@1224|Proteobacteria,2US1V@28211|Alphaproteobacteria,1JXWU@119045|Methylobacteriaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4925769_9	290397.Adeh_0078	5.449e-42	166.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4925769_2	1254432.SCE1572_18250	1.517e-145	491.0	COG0515@1|root,COG0515@2|Bacteria,1PBV3@1224|Proteobacteria,438HA@68525|delta/epsilon subdivisions,2X3S2@28221|Deltaproteobacteria,2YWZ2@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_4934957_0	448385.sce2571	0.0	2158.0	COG0178@1|root,COG0178@2|Bacteria,1MW0W@1224|Proteobacteria,42P3V@68525|delta/epsilon subdivisions,2WKWV@28221|Deltaproteobacteria,2YTVV@29|Myxococcales	28221|Deltaproteobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA1	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
SHD3_k127_4934957_2	1192034.CAP_5473	1.852e-44	169.0	COG0691@1|root,COG0691@2|Bacteria,1RDFP@1224|Proteobacteria,42SJ8@68525|delta/epsilon subdivisions,2WP5B@28221|Deltaproteobacteria,2YVUD@29|Myxococcales	28221|Deltaproteobacteria	J	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
SHD3_k127_4934957_5	1254432.SCE1572_50150	5.206e-12	79.0	COG1729@1|root,COG3712@1|root,COG1729@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_6,WG_beta_rep
SHD3_k127_4934957_1	1192034.CAP_7224	6.072e-63	223.0	COG1595@1|root,COG1595@2|Bacteria,1N4RS@1224|Proteobacteria,43E0K@68525|delta/epsilon subdivisions,2WZCJ@28221|Deltaproteobacteria,2Z1UN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_4934957_3	448385.sce8329	1.717e-40	166.0	COG1716@1|root,COG1716@2|Bacteria,1Q8QY@1224|Proteobacteria,437GG@68525|delta/epsilon subdivisions,2X2P3@28221|Deltaproteobacteria,2Z08U@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
SHD3_k127_4934957_4	1192034.CAP_4702	1.524e-21	108.0	2E2XW@1|root,32XYS@2|Bacteria,1N3ID@1224|Proteobacteria,42UFM@68525|delta/epsilon subdivisions,2WQKF@28221|Deltaproteobacteria,2YVPU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4937865_7	1254432.SCE1572_04930	4.207e-05	51.0	COG4886@1|root,COG4886@2|Bacteria,1R9FD@1224|Proteobacteria,42XXN@68525|delta/epsilon subdivisions,2WVUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Leucine-rich repeat (LRR) protein	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	LRR_4
SHD3_k127_4937865_3	595460.RRSWK_02687	8.467e-27	110.0	COG1278@1|root,COG1278@2|Bacteria,2J13Y@203682|Planctomycetes	203682|Planctomycetes	K	COG1278 Cold shock	-	-	-	-	-	-	-	-	-	-	-	-	CSD
SHD3_k127_4937865_6	378806.STAUR_6021	9.868e-07	53.0	2AGWF@1|root,3174U@2|Bacteria,1PYDK@1224|Proteobacteria,435AC@68525|delta/epsilon subdivisions,2WZMD@28221|Deltaproteobacteria,2Z2DC@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4937865_2	3827.XP_004489519.1	1.021e-27	116.0	KOG0118@1|root,KOG0118@2759|Eukaryota,37SIW@33090|Viridiplantae,3GBC5@35493|Streptophyta,4JP0Q@91835|fabids	35493|Streptophyta	A	Glycine-rich RNA-binding protein	-	-	-	ko:K12741	ko03040,map03040	-	-	-	ko00000,ko00001,ko03019,ko03041	-	-	-	RRM_1
SHD3_k127_4937865_5	1304275.C41B8_08470	3.232e-11	72.0	2C6T2@1|root,32ZMJ@2|Bacteria,1R3H1@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF3892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3892
SHD3_k127_4937865_8	1232447.BAHW02000009_gene270	0.0002496	43.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,267PJ@186813|unclassified Clostridiales	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SHD3_k127_4937865_4	59374.Fisuc_2250	2.02e-20	106.0	COG5520@1|root,COG5520@2|Bacteria	2|Bacteria	M	Belongs to the glycosyl hydrolase 30 family	-	-	3.2.1.136,3.2.1.55,3.2.1.8	ko:K01181,ko:K15921,ko:K15924	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM6,GH43,GH5	-	Beta_helix,Binary_toxB_2,Binary_toxB_3,CBM_6,CW_binding_1,Dockerin_1,Glyco_hydro_10,Glyco_hydro_30,Glyco_hydro_30C,Glyco_hydro_43,Lipase_GDSL_2,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_4937865_0	1163671.JAGI01000002_gene3342	4.179e-114	383.0	COG5520@1|root,COG5520@2|Bacteria,1U8RG@1239|Firmicutes,248NT@186801|Clostridia,36H0Z@31979|Clostridiaceae	186801|Clostridia	G	dockerin type	xynC1	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_2,CBM_4_9,CBM_6,Dockerin_1,Esterase,Glyco_hydro_30,Glyco_hydro_30C,Polysacc_deac_1,RicinB_lectin_2
SHD3_k127_4939900_2	671143.DAMO_0414	1.358e-36	142.0	COG0642@1|root,COG2205@2|Bacteria,2NNNV@2323|unclassified Bacteria	2|Bacteria	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
SHD3_k127_4939900_1	404589.Anae109_3104	1.725e-84	286.0	COG0745@1|root,COG0745@2|Bacteria,1MWZ5@1224|Proteobacteria,42QTM@68525|delta/epsilon subdivisions,2WN5R@28221|Deltaproteobacteria,2YZM4@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_4939900_0	562970.Btus_2864	5.281e-128	419.0	COG0226@1|root,COG0226@2|Bacteria,1TYCT@1239|Firmicutes,4I7GX@91061|Bacilli,279TX@186823|Alicyclobacillaceae	91061|Bacilli	P	Belongs to the PstS family	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
SHD3_k127_4939900_3	1254432.SCE1572_17925	4.143e-10	63.0	COG0573@1|root,COG0573@2|Bacteria,1MVKP@1224|Proteobacteria,42N2N@68525|delta/epsilon subdivisions,2WK67@28221|Deltaproteobacteria,2Z25A@29|Myxococcales	28221|Deltaproteobacteria	U	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	iAF987.Gmet_2702	BPD_transp_1
SHD3_k127_4944701_2	622637.KE124774_gene726	6.043e-76	270.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,2TQR7@28211|Alphaproteobacteria,36XJZ@31993|Methylocystaceae	28211|Alphaproteobacteria	NT	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	HAMP,MCPsignal,PAS_3,PAS_4,PAS_8,PAS_9
SHD3_k127_4944701_4	1144275.COCOR_05358	2.77e-22	101.0	COG0745@1|root,COG0745@2|Bacteria,1RDYB@1224|Proteobacteria	1224|Proteobacteria	T	response regulator	pilG	-	-	ko:K02657,ko:K03413	ko02020,ko02025,ko02030,map02020,map02025,map02030	M00506,M00507	-	-	ko00000,ko00001,ko00002,ko02022,ko02035,ko02044	-	-	-	Response_reg
SHD3_k127_4944701_5	1157632.AQWQ01000015_gene3478	8.171e-08	64.0	COG2815@1|root,COG3693@1|root,COG4447@1|root,COG2815@2|Bacteria,COG3693@2|Bacteria,COG4447@2|Bacteria,2GJF7@201174|Actinobacteria	201174|Actinobacteria	G	cellulose binding	xeg74	-	-	-	-	-	-	-	-	-	-	-	BNR,CBM_2
SHD3_k127_4944701_1	401526.TcarDRAFT_2684	9.027e-80	280.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,4H3FV@909932|Negativicutes	909932|Negativicutes	S	DNA modification repair radical SAM protein	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
SHD3_k127_4944701_0	448385.sce4520	6.797e-98	334.0	COG5557@1|root,COG5557@2|Bacteria,1QURB@1224|Proteobacteria,43BT1@68525|delta/epsilon subdivisions,2X73S@28221|Deltaproteobacteria,2Z3JY@29|Myxococcales	28221|Deltaproteobacteria	C	Pfam Polysulphide reductase, NrfD	actF	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4944701_3	1254432.SCE1572_27545	4.498e-36	144.0	COG2010@1|root,COG2010@2|Bacteria,1RHGQ@1224|Proteobacteria,4393P@68525|delta/epsilon subdivisions,2X49M@28221|Deltaproteobacteria,2YYJI@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
SHD3_k127_495300_1	29581.BW37_00307	1.836e-131	437.0	COG0612@1|root,COG0612@2|Bacteria,1MVST@1224|Proteobacteria,2VHVB@28216|Betaproteobacteria,472VG@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_495300_5	1267534.KB906754_gene3138	1.218e-61	232.0	COG0612@1|root,COG0612@2|Bacteria,3Y2UB@57723|Acidobacteria,2JITC@204432|Acidobacteriia	204432|Acidobacteriia	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
SHD3_k127_495300_0	1254432.SCE1572_42080	3.422e-233	740.0	COG0745@1|root,COG2202@1|root,COG2203@1|root,COG5002@1|root,COG0745@2|Bacteria,COG2202@2|Bacteria,COG2203@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CW5@68525|delta/epsilon subdivisions,2X845@28221|Deltaproteobacteria,2Z3KI@29|Myxococcales	28221|Deltaproteobacteria	KT	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HisKA,PAS,Response_reg
SHD3_k127_495300_4	448385.sce7218	5.678e-73	261.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42S9W@68525|delta/epsilon subdivisions,2WNX4@28221|Deltaproteobacteria,2YUXR@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA,PAS,PAS_4,PAS_8
SHD3_k127_495300_3	448385.sce7221	8.337e-89	301.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42U04@68525|delta/epsilon subdivisions,2WQA9@28221|Deltaproteobacteria,2YV9U@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_495300_2	1192034.CAP_2859	2.85e-117	387.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YYCB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_4956894_14	324602.Caur_2646	6.237e-09	67.0	COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,2G7NF@200795|Chloroflexi,374TJ@32061|Chloroflexia	32061|Chloroflexia	T	histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS
SHD3_k127_4956894_13	1172185.KB911509_gene570	1.395e-11	77.0	COG1864@1|root,COG3591@1|root,COG1864@2|Bacteria,COG3591@2|Bacteria,2GM9R@201174|Actinobacteria,4G9DJ@85025|Nocardiaceae	201174|Actinobacteria	EF	DNA/RNA non-specific endonuclease	-	-	-	ko:K01173	ko04210,map04210	-	-	-	ko00000,ko00001,ko03029	-	-	-	Endonuclease_1,Endonuclease_NS,Trypsin_2
SHD3_k127_4956894_12	935866.JAER01000073_gene3593	9.902e-13	70.0	COG4634@1|root,COG4634@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4956894_11	1254432.SCE1572_40970	1.533e-22	113.0	2F8GF@1|root,340V9@2|Bacteria,1NXZ0@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4956894_4	1278073.MYSTI_00789	1.032e-83	290.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	yfbL	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SHD3_k127_4956894_9	335543.Sfum_3425	2.91e-45	172.0	COG2227@1|root,COG2227@2|Bacteria,1MU89@1224|Proteobacteria	1224|Proteobacteria	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
SHD3_k127_4956894_10	472759.Nhal_2791	6.738e-23	104.0	COG2885@1|root,COG2885@2|Bacteria,1REH1@1224|Proteobacteria,1S4WV@1236|Gammaproteobacteria,1WZ8J@135613|Chromatiales	135613|Chromatiales	M	Belongs to the ompA family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4398,OmpA
SHD3_k127_4956894_2	261292.Nit79A3_3156	3.822e-136	452.0	COG1858@1|root,COG1858@2|Bacteria,1REQ9@1224|Proteobacteria	1224|Proteobacteria	P	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
SHD3_k127_4956894_8	1254432.SCE1572_17480	8.736e-52	193.0	COG0564@1|root,COG0564@2|Bacteria,1N8GW@1224|Proteobacteria,42RAV@68525|delta/epsilon subdivisions,2WNTB@28221|Deltaproteobacteria,2Z0SP@29|Myxococcales	28221|Deltaproteobacteria	J	RNA pseudouridylate synthase	truC	-	5.4.99.26	ko:K06175	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_2
SHD3_k127_4956894_5	1499967.BAYZ01000028_gene1235	9.566e-80	280.0	COG0384@1|root,COG0384@2|Bacteria	2|Bacteria	S	isomerase activity	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
SHD3_k127_4956894_3	1123023.JIAI01000001_gene6265	2.423e-94	315.0	COG0426@1|root,COG0426@2|Bacteria,2GKJ9@201174|Actinobacteria	201174|Actinobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4956894_6	1122604.JONR01000011_gene3616	2.583e-67	236.0	COG0778@1|root,COG0778@2|Bacteria,1RDJ6@1224|Proteobacteria,1SXRF@1236|Gammaproteobacteria,1XAGK@135614|Xanthomonadales	1224|Proteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SHD3_k127_4956894_0	713586.KB900536_gene1551	1.264e-200	634.0	COG1350@1|root,COG1350@2|Bacteria,1N07Y@1224|Proteobacteria,1RMGK@1236|Gammaproteobacteria,1WWHA@135613|Chromatiales	135613|Chromatiales	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SHD3_k127_4956894_7	1254432.SCE1572_30780	9.375e-60	221.0	2C5NX@1|root,32RFY@2|Bacteria,1QTDQ@1224|Proteobacteria,438EN@68525|delta/epsilon subdivisions,2X3PK@28221|Deltaproteobacteria,2YWSG@29|Myxococcales	28221|Deltaproteobacteria	S	GRAS domain family	-	-	-	-	-	-	-	-	-	-	-	-	GRAS
SHD3_k127_4956894_1	215803.DB30_2529	1.733e-143	471.0	COG0488@1|root,COG0488@2|Bacteria,1QUVR@1224|Proteobacteria,42P66@68525|delta/epsilon subdivisions,2WJ2D@28221|Deltaproteobacteria,2YWET@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
SHD3_k127_4963718_2	1254432.SCE1572_27800	1.881e-66	244.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,439RU@68525|delta/epsilon subdivisions,2X54N@28221|Deltaproteobacteria,2Z03Z@29|Myxococcales	28221|Deltaproteobacteria	K	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Sigma54_activat
SHD3_k127_4963718_3	1192034.CAP_0460	3.244e-65	245.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	68525|delta/epsilon subdivisions	KLT	Family membership	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PP2C_2,Pkinase
SHD3_k127_4963718_4	448385.sce0634	8.648e-10	70.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce0634|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4963718_1	59374.Fisuc_1584	5.539e-122	401.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	celC	GO:0005575,GO:0005576	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_4963718_0	502025.Hoch_6684	1.63e-258	811.0	COG1048@1|root,COG1048@2|Bacteria,1MU9T@1224|Proteobacteria,42M33@68525|delta/epsilon subdivisions,2WJGS@28221|Deltaproteobacteria,2YU96@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
SHD3_k127_4976353_10	1382306.JNIM01000001_gene1402	1.285e-17	88.0	COG1985@1|root,COG1985@2|Bacteria,2G97Y@200795|Chloroflexi	200795|Chloroflexi	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SHD3_k127_4976353_6	292459.STH770	4.739e-49	192.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia	1239|Firmicutes	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
SHD3_k127_4976353_2	1396141.BATP01000023_gene619	4.005e-153	502.0	COG1070@1|root,COG1070@2|Bacteria,46UPD@74201|Verrucomicrobia,2IV4A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
SHD3_k127_4976353_1	1242864.D187_001888	2.004e-186	593.0	COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,438FH@68525|delta/epsilon subdivisions,2X3QH@28221|Deltaproteobacteria,2YWUI@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
SHD3_k127_4976353_12	483219.LILAB_30845	0.0008456	51.0	2ANK1@1|root,31DJ4@2|Bacteria,1QAV1@1224|Proteobacteria,435BA@68525|delta/epsilon subdivisions,2WZNP@28221|Deltaproteobacteria,2Z2FG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4976353_4	448385.sce3783	1.879e-75	267.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_4976353_0	502025.Hoch_6864	1.818e-210	670.0	COG1164@1|root,COG1164@2|Bacteria,1MXAC@1224|Proteobacteria,42NAD@68525|delta/epsilon subdivisions,2WKEY@28221|Deltaproteobacteria,2Z1IJ@29|Myxococcales	28221|Deltaproteobacteria	E	PFAM peptidase M3A and M3B thimet oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
SHD3_k127_4976353_3	452637.Oter_2315	1.775e-101	347.0	COG2211@1|root,COG2211@2|Bacteria,46UFW@74201|Verrucomicrobia	74201|Verrucomicrobia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
SHD3_k127_4976353_7	1242864.D187_007972	1.299e-24	112.0	COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria,1N9AN@1224|Proteobacteria,42XYC@68525|delta/epsilon subdivisions,2WSN6@28221|Deltaproteobacteria,2Z267@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,VanY
SHD3_k127_4976353_8	1123242.JH636434_gene3185	7.606e-22	107.0	COG0394@1|root,COG0394@2|Bacteria,2J0YU@203682|Planctomycetes	203682|Planctomycetes	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
SHD3_k127_4977772_0	1254432.SCE1572_03510	4.678e-83	279.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,430UT@68525|delta/epsilon subdivisions,2X6PU@28221|Deltaproteobacteria,2Z3C4@29|Myxococcales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF5110)	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
SHD3_k127_4977772_2	448385.sce3900	1.904e-30	124.0	COG0805@1|root,COG0805@2|Bacteria,1MVAY@1224|Proteobacteria,42MM7@68525|delta/epsilon subdivisions,2WKJW@28221|Deltaproteobacteria,2YVGX@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
SHD3_k127_4977772_1	1254432.SCE1572_40265	5.797e-82	282.0	COG0726@1|root,COG0726@2|Bacteria,1R7W4@1224|Proteobacteria,43DTW@68525|delta/epsilon subdivisions,2X8WG@28221|Deltaproteobacteria,2Z0PP@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 11 (cellulase G) family	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_11
SHD3_k127_4977772_3	156889.Mmc1_2864	3.764e-27	115.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
SHD3_k127_4977772_4	384765.SIAM614_30906	1.697e-10	65.0	COG3405@1|root,COG3405@2|Bacteria,1N41Q@1224|Proteobacteria,2U0D1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Glycosyl hydrolases family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_8
SHD3_k127_4984678_1	452637.Oter_2107	9.508e-216	678.0	COG0034@1|root,COG0034@2|Bacteria,46SSU@74201|Verrucomicrobia	74201|Verrucomicrobia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7
SHD3_k127_4984678_0	56780.SYN_02589	0.0	1643.0	COG0458@1|root,COG0458@2|Bacteria,1NPMZ@1224|Proteobacteria,42NF3@68525|delta/epsilon subdivisions,2WM4C@28221|Deltaproteobacteria,2MQ8X@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Carbamoyl-phosphate synthetase large chain, oligomerisation	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
SHD3_k127_4984678_9	1297742.A176_06263	5.985e-54	200.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Acetyltransf_9,DUF952
SHD3_k127_4984678_7	661478.OP10G_1682	7.399e-88	306.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SHD3_k127_4984678_6	304371.MCP_0027	2.929e-99	349.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,Radical_SAM
SHD3_k127_4984678_12	1254432.SCE1572_18405	4.009e-06	57.0	COG0400@1|root,COG0400@2|Bacteria	2|Bacteria	S	palmitoyl-(protein) hydrolase activity	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,Abhydrolase_2,Abhydrolase_4,Esterase
SHD3_k127_4984678_3	909663.KI867150_gene1228	3.732e-121	394.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,42M44@68525|delta/epsilon subdivisions,2WJFW@28221|Deltaproteobacteria,2MQ9U@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
SHD3_k127_4984678_5	1156937.MFUM_40010	2.403e-107	363.0	COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia,37H6N@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_4984678_4	290397.Adeh_3183	2.211e-117	397.0	2DPRW@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG5002@1|root,3334N@2|Bacteria,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
SHD3_k127_4984678_8	391625.PPSIR1_34257	1.192e-59	217.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2Z1F1@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_4984678_2	243090.RB5820	2.406e-127	416.0	COG0667@1|root,COG0667@2|Bacteria	2|Bacteria	C	Aldo Keto reductase	-	-	1.1.1.122	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	M00114	R07675,R08926	RC00066,RC00161	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldo_ket_red
SHD3_k127_4984678_11	243231.GSU2422	1.462e-13	78.0	COG0680@1|root,COG0680@2|Bacteria,1PI7E@1224|Proteobacteria,42X63@68525|delta/epsilon subdivisions,2WSJX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	Hydrogenase maturation protease	mvhP	-	-	-	-	-	-	-	-	-	-	-	HycI
SHD3_k127_4984678_10	585.DR95_866	1.727e-15	83.0	COG0635@1|root,COG0635@2|Bacteria,1NTDN@1224|Proteobacteria,1RPGS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	H	coproporphyrinogen III oxidase	hutW	-	2.1.1.342	ko:K21936	-	-	R11700	-	ko00000,ko01000	-	-	-	ChuX_HutX,Radical_SAM
SHD3_k127_4989875_6	1192034.CAP_8138	7.684e-12	78.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	CHU_C,PA14,PD40,PKD
SHD3_k127_4989875_4	335543.Sfum_0500	8.476e-88	296.0	COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,42RIR@68525|delta/epsilon subdivisions,2WP3R@28221|Deltaproteobacteria,2MSCP@213462|Syntrophobacterales	28221|Deltaproteobacteria	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
SHD3_k127_4989875_3	1254432.SCE1572_17835	5.537e-108	374.0	COG0457@1|root,COG0457@2|Bacteria,1NJ9F@1224|Proteobacteria	1224|Proteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4989875_5	522306.CAP2UW1_0486	5.881e-85	290.0	COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,2VIRP@28216|Betaproteobacteria,1KPZN@119066|unclassified Betaproteobacteria	28216|Betaproteobacteria	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
SHD3_k127_4989875_1	1121434.AULY01000007_gene1289	6.971e-151	488.0	COG0126@1|root,COG0126@2|Bacteria,1MUNU@1224|Proteobacteria,42N4P@68525|delta/epsilon subdivisions,2WJ0B@28221|Deltaproteobacteria,2M7RZ@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Belongs to the phosphoglycerate kinase family	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
SHD3_k127_4989875_2	1480694.DC28_00370	1.141e-130	427.0	COG0057@1|root,COG0057@2|Bacteria,2J5AD@203691|Spirochaetes	203691|Spirochaetes	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gap	GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
SHD3_k127_4989875_0	1123008.KB905705_gene933	1.353e-151	487.0	COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae	976|Bacteroidetes	G	Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
SHD3_k127_4989875_7	1321778.HMPREF1982_04262	3.672e-10	62.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,2688K@186813|unclassified Clostridiales	186801|Clostridia	G	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
SHD3_k127_4995899_1	59374.Fisuc_1228	7.813e-97	323.0	COG1173@1|root,COG1173@2|Bacteria	2|Bacteria	P	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	iLJ478.TM0029	BPD_transp_1,OppC_N
SHD3_k127_4995899_0	946483.Cenrod_0136	5.534e-124	404.0	COG0444@1|root,COG0444@2|Bacteria,1R4KB@1224|Proteobacteria,2W0NK@28216|Betaproteobacteria	28216|Betaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
SHD3_k127_4995899_2	59374.Fisuc_1226	8.13e-90	303.0	COG4608@1|root,COG4608@2|Bacteria	2|Bacteria	P	Belongs to the ABC transporter superfamily	nikV	-	3.6.3.24	ko:K02031,ko:K02032,ko:K10823,ko:K10824	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439,M00440	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
SHD3_k127_4995899_3	1268237.G114_05495	1.745e-46	175.0	COG2102@1|root,COG2102@2|Bacteria,1MUU2@1224|Proteobacteria,1S3D2@1236|Gammaproteobacteria,1Y5C1@135624|Aeromonadales	135624|Aeromonadales	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
SHD3_k127_4995899_4	314278.NB231_02858	2.168e-34	141.0	2CBKC@1|root,32RTJ@2|Bacteria,1N5I0@1224|Proteobacteria,1SACI@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_4995899_5	1242864.D187_006227	7.7e-19	87.0	COG2730@1|root,COG4447@1|root,COG2730@2|Bacteria,COG4447@2|Bacteria,1R5GC@1224|Proteobacteria,434P8@68525|delta/epsilon subdivisions,2WZ0H@28221|Deltaproteobacteria,2Z12C@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_499784_1	765912.Thimo_2911	9.344e-178	563.0	COG1449@1|root,COG1449@2|Bacteria,1R3Z3@1224|Proteobacteria,1RNRC@1236|Gammaproteobacteria,1WVY7@135613|Chromatiales	135613|Chromatiales	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_57
SHD3_k127_499784_6	1547445.LO80_05900	2.721e-63	229.0	COG1073@1|root,COG1073@2|Bacteria,1MUCD@1224|Proteobacteria,1RP4I@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	AXE1,Abhydrolase_6,Hydrolase_4,Peptidase_S15
SHD3_k127_499784_5	1254432.SCE1572_15140	1.116e-77	273.0	28V7D@1|root,2ZHAI@2|Bacteria,1RA29@1224|Proteobacteria,42R9H@68525|delta/epsilon subdivisions,2WN1D@28221|Deltaproteobacteria,2Z26N@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
SHD3_k127_499784_0	1254432.SCE1572_15145	7.303e-196	628.0	COG3225@1|root,COG3225@2|Bacteria,1MY63@1224|Proteobacteria,42N95@68525|delta/epsilon subdivisions,2WJ0N@28221|Deltaproteobacteria,2Z1WX@29|Myxococcales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
SHD3_k127_499784_4	448385.sce2533	7.467e-83	281.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2YVMT@29|Myxococcales	28221|Deltaproteobacteria	N	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3,ABC_transp_aux
SHD3_k127_499784_2	1254432.SCE1572_15155	4.889e-147	475.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria,2YUUC@29|Myxococcales	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_499784_7	246197.MXAN_5647	1.148e-51	194.0	COG4790@1|root,COG4790@2|Bacteria,1R34E@1224|Proteobacteria,42P10@68525|delta/epsilon subdivisions,2WK6A@28221|Deltaproteobacteria,2YYE5@29|Myxococcales	28221|Deltaproteobacteria	U	FliP family	-	-	-	ko:K03226	ko03070,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02044	3.A.6.1,3.A.6.3	-	-	FliP
SHD3_k127_499784_3	1192034.CAP_5270	1.581e-142	464.0	COG1629@1|root,COG4771@2|Bacteria,1QX4E@1224|Proteobacteria,437VM@68525|delta/epsilon subdivisions,2X358@28221|Deltaproteobacteria,2YUBU@29|Myxococcales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_C,TonB_dep_Rec
SHD3_k127_499784_8	483219.LILAB_09745	2.873e-05	56.0	2B37D@1|root,31VVE@2|Bacteria,1QTRA@1224|Proteobacteria,4382S@68525|delta/epsilon subdivisions,2X3CT@28221|Deltaproteobacteria,2YVG4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5003239_0	945713.IALB_1070	3.46e-223	707.0	COG1012@1|root,COG1012@2|Bacteria	2|Bacteria	C	belongs to the aldehyde dehydrogenase family	pruA	-	1.2.1.88	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	-	R00245,R00707,R00708,R04444,R04445,R05051	RC00080,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000	-	-	-	Aldedh
SHD3_k127_5003239_1	1192034.CAP_5016	1.405e-98	326.0	COG0745@1|root,COG0745@2|Bacteria,1NUNK@1224|Proteobacteria,43CMR@68525|delta/epsilon subdivisions,2X7UV@28221|Deltaproteobacteria,2Z3I4@29|Myxococcales	28221|Deltaproteobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Response_reg
SHD3_k127_5008871_1	1254432.SCE1572_11630	1.469e-76	265.0	arCOG10456@1|root,2ZA6T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5008871_0	1242864.D187_009527	6.393e-216	692.0	COG0475@1|root,COG0589@1|root,COG0475@2|Bacteria,COG0589@2|Bacteria,1MVGV@1224|Proteobacteria,42WJ6@68525|delta/epsilon subdivisions,2WQ9K@28221|Deltaproteobacteria,2YXTM@29|Myxococcales	28221|Deltaproteobacteria	PT	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,Usp
SHD3_k127_5022005_2	269798.CHU_2852	3.982e-58	219.0	COG3405@1|root,COG5295@1|root,COG3405@2|Bacteria,COG5295@2|Bacteria,4NF6Q@976|Bacteroidetes,47KN7@768503|Cytophagia	976|Bacteroidetes	GUW	candidate b-glycosidase, glycoside hydrolase family 8 protein	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_3_3,M60-like_N,NosD,Peptidase_M60
SHD3_k127_5022005_0	398512.JQKC01000004_gene5283	2.383e-113	380.0	COG2755@1|root,COG2755@2|Bacteria,1UYZ1@1239|Firmicutes,24BMN@186801|Clostridia,3WJP1@541000|Ruminococcaceae	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
SHD3_k127_5022005_5	398578.Daci_6012	3.519e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,1MXVA@1224|Proteobacteria,2VK3C@28216|Betaproteobacteria,4AC81@80864|Comamonadaceae	28216|Betaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5022005_1	448385.sce4949	2.866e-63	237.0	COG0402@1|root,COG1506@1|root,COG5184@1|root,COG0402@2|Bacteria,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_5022005_4	240015.ACP_3430	6.036e-06	55.0	COG3664@1|root,COG3664@2|Bacteria,3Y3B7@57723|Acidobacteria,2JKTF@204432|Acidobacteriia	204432|Acidobacteriia	G	Glycosyl hydrolases family 39	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_39
SHD3_k127_5023937_1	483219.LILAB_27255	2.401e-79	270.0	COG4430@1|root,COG4430@2|Bacteria,1NEN6@1224|Proteobacteria,4386R@68525|delta/epsilon subdivisions,2X9ZT@28221|Deltaproteobacteria,2YUYI@29|Myxococcales	28221|Deltaproteobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
SHD3_k127_5023937_5	215803.DB30_8223	1.073e-20	103.0	COG3391@1|root,COG3391@2|Bacteria,1QX9W@1224|Proteobacteria,43C32@68525|delta/epsilon subdivisions,2X7DQ@28221|Deltaproteobacteria,2YVS2@29|Myxococcales	28221|Deltaproteobacteria	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_5023937_6	1144275.COCOR_07153	1.937e-20	104.0	COG3391@1|root,COG3391@2|Bacteria,1QX9W@1224|Proteobacteria,43C32@68525|delta/epsilon subdivisions,2X7DQ@28221|Deltaproteobacteria,2YVS2@29|Myxococcales	28221|Deltaproteobacteria	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_5023937_9	575540.Isop_0599	2.085e-05	49.0	COG2006@1|root,COG2006@2|Bacteria,2J2FX@203682|Planctomycetes	203682|Planctomycetes	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_5023937_4	118163.Ple7327_2879	3.159e-31	140.0	28N8A@1|root,2ZBCR@2|Bacteria,1G2Q6@1117|Cyanobacteria,3VMJF@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5023937_8	1096546.WYO_5203	1.132e-06	60.0	COG0438@1|root,COG0457@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,1R07A@1224|Proteobacteria,2UYK8@28211|Alphaproteobacteria,1JWQY@119045|Methylobacteriaceae	28211|Alphaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SHD3_k127_5023937_0	404380.Gbem_2934	1.027e-193	616.0	COG1232@1|root,COG1232@2|Bacteria,1MX35@1224|Proteobacteria,42QDK@68525|delta/epsilon subdivisions	1224|Proteobacteria	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
SHD3_k127_5023937_3	742726.HMPREF9448_01911	6.599e-38	146.0	COG2246@1|root,COG2246@2|Bacteria,4NXZ2@976|Bacteroidetes	976|Bacteroidetes	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
SHD3_k127_5023937_7	1254432.SCE1572_02325	5.308e-14	83.0	2DK48@1|root,308EE@2|Bacteria,1QSG3@1224|Proteobacteria,4357G@68525|delta/epsilon subdivisions,2WZIH@28221|Deltaproteobacteria,2Z27V@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5023937_2	357808.RoseRS_0421	7.791e-75	278.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,37639@32061|Chloroflexia	32061|Chloroflexia	DZ	Regulator of chromosome condensation (RCC1) repeat	-	-	-	-	-	-	-	-	-	-	-	-	RCC1_2
SHD3_k127_5027579_4	1173024.KI912148_gene2732	1.889e-08	67.0	COG5563@1|root,COG5563@2|Bacteria,1GASM@1117|Cyanobacteria	1117|Cyanobacteria	S	Extracellular repeat protein, HAF family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3466
SHD3_k127_5027579_0	1079986.JH164846_gene1966	2.395e-103	359.0	COG3693@1|root,COG3693@2|Bacteria,2GJSN@201174|Actinobacteria	201174|Actinobacteria	G	PFAM glycoside hydrolase, family 10	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_10,Glyco_hydro_62,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_5027579_2	326427.Cagg_0670	8.394e-69	253.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	200795|Chloroflexi	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_5027579_6	348824.LPU83_pLPU83a_0112	0.0007856	46.0	COG0389@1|root,COG0389@2|Bacteria,1MU5X@1224|Proteobacteria,2TQVR@28211|Alphaproteobacteria,4B7G3@82115|Rhizobiaceae	28211|Alphaproteobacteria	L	Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
SHD3_k127_5027579_5	223926.28809294	2.641e-07	61.0	COG1361@1|root,COG5295@1|root,COG1361@2|Bacteria,COG5295@2|Bacteria,1MUQC@1224|Proteobacteria,1T39T@1236|Gammaproteobacteria,1XUYV@135623|Vibrionales	135623|Vibrionales	M	Gametolysin peptidase M11	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc,Peptidase_M11
SHD3_k127_5027579_1	330214.NIDE3608	4.978e-92	323.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874,Glyco_hydro_42
SHD3_k127_5030614_5	448385.sce0763	5.879e-08	59.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_binding_2,FTP,FlgD_ig,PPC,Peptidase_M4,Peptidase_M4_C,RicinB_lectin_2,SBBP,TIG,Trypsin,VCBS
SHD3_k127_5030614_3	448385.sce6176	3.66e-80	274.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,42VWF@68525|delta/epsilon subdivisions,2WRX8@28221|Deltaproteobacteria,2YVKZ@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the DNA glycosylase MPG family	-	-	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
SHD3_k127_5030614_4	1297742.A176_02250	1.355e-41	160.0	COG0454@1|root,COG0456@2|Bacteria,1N2EC@1224|Proteobacteria,437FF@68525|delta/epsilon subdivisions,2X2N2@28221|Deltaproteobacteria,2YZX8@29|Myxococcales	28221|Deltaproteobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
SHD3_k127_5030614_0	1156937.MFUM_40010	2.221e-137	447.0	COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia,37H6N@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	G	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_5030614_1	448385.sce3103	4.587e-134	439.0	COG1262@1|root,COG1262@2|Bacteria,1R6GS@1224|Proteobacteria,42XMH@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Protein of unknown function (DUF1566)	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3,DUF1566,EF-hand_5
SHD3_k127_5030614_2	886293.Sinac_0959	5.058e-101	333.0	COG0176@1|root,COG0176@2|Bacteria,2IYC8@203682|Planctomycetes	203682|Planctomycetes	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	-	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
SHD3_k127_5033346_1	1297742.A176_07603	4.969e-51	195.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_5033346_3	448385.sce8709	0.0002279	53.0	COG1538@1|root,COG1538@2|Bacteria,1R6VY@1224|Proteobacteria,430DM@68525|delta/epsilon subdivisions,2WVTG@28221|Deltaproteobacteria,2YVRS@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	czcC	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
SHD3_k127_5033346_2	378806.STAUR_1200	3.658e-35	154.0	COG0845@1|root,COG0845@2|Bacteria,1MX8W@1224|Proteobacteria,42T6A@68525|delta/epsilon subdivisions,2WPV8@28221|Deltaproteobacteria,2YUNA@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
SHD3_k127_5033346_0	1297742.A176_03031	1.093e-129	430.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42M0A@68525|delta/epsilon subdivisions,2WIQY@28221|Deltaproteobacteria,2YTUC@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787,ko:K15726	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.2,2.A.6.1.4	-	-	ACR_tran
SHD3_k127_5050863_4	338966.Ppro_3531	1.069e-39	156.0	COG1009@1|root,COG1009@2|Bacteria,1QV11@1224|Proteobacteria,43CGR@68525|delta/epsilon subdivisions,2X7RW@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	-	-	-	ko:K12137	-	-	-	-	ko00000,ko01000	-	-	-	Proton_antipo_M
SHD3_k127_5050863_0	338966.Ppro_3532	2.025e-171	553.0	COG1009@1|root,COG1009@2|Bacteria,1MW2M@1224|Proteobacteria,43CGQ@68525|delta/epsilon subdivisions,2X7RV@28221|Deltaproteobacteria	1224|Proteobacteria	C	PFAM NADH Ubiquinone plastoquinone (complex I)	hyfD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00341,ko:K05568,ko:K12139,ko:K14086	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	iEcSMS35_1347.EcSMS35_2631	Proton_antipo_M,Proton_antipo_N
SHD3_k127_5050863_3	1408419.JHYG01000002_gene1063	1.359e-74	262.0	COG3774@1|root,COG3774@2|Bacteria	2|Bacteria	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Gly_transf_sug,MLD
SHD3_k127_5050863_6	1133849.O3I_011205	2.01e-24	114.0	COG3233@1|root,COG3233@2|Bacteria,2HMCU@201174|Actinobacteria,4FWDB@85025|Nocardiaceae	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2334)	-	-	-	ko:K06986	-	-	-	-	ko00000	-	-	-	DUF2334
SHD3_k127_5050863_2	1254432.SCE1572_07390	1.886e-75	272.0	COG0438@1|root,COG0438@2|Bacteria,1NU0D@1224|Proteobacteria,431K6@68525|delta/epsilon subdivisions,2WWVM@28221|Deltaproteobacteria,2Z1M9@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase Family 4	-	-	-	ko:K14335	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_5050863_5	215803.DB30_4465	7.749e-37	152.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,42SA7@68525|delta/epsilon subdivisions,2WNRU@28221|Deltaproteobacteria,2YU91@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SHD3_k127_5050863_1	1254432.SCE1572_43245	3.542e-159	507.0	COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,42ZA3@68525|delta/epsilon subdivisions,2WUE3@28221|Deltaproteobacteria,2Z36C@29|Myxococcales	28221|Deltaproteobacteria	F	Metal binding domain of Ada	-	-	2.1.1.63	ko:K10778	-	-	-	-	ko00000,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,DNA_binding_1,HTH_18
SHD3_k127_505259_2	396588.Tgr7_2382	1.756e-132	430.0	COG0171@1|root,COG0171@2|Bacteria,1QHZ4@1224|Proteobacteria,1RXE1@1236|Gammaproteobacteria,1WZVQ@135613|Chromatiales	135613|Chromatiales	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source	-	-	6.3.1.5	ko:K01916	ko00760,ko01100,map00760,map01100	M00115	R00189	RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	NAD_synthase
SHD3_k127_505259_0	1254432.SCE1572_22980	9.608e-278	874.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria,2YUPX@29|Myxococcales	28221|Deltaproteobacteria	E	Asparagine synthase	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
SHD3_k127_505259_1	448385.sce3825	5.493e-205	650.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,42M5F@68525|delta/epsilon subdivisions,2WJ00@28221|Deltaproteobacteria,2YURH@29|Myxococcales	28221|Deltaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD1	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
SHD3_k127_505259_6	1254432.SCE1572_22970	1.812e-23	102.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,42VU0@68525|delta/epsilon subdivisions,2WRU6@28221|Deltaproteobacteria,2Z2NF@29|Myxococcales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
SHD3_k127_505259_3	448385.sce0876	1.526e-113	389.0	COG1716@1|root,COG2208@1|root,COG1716@2|Bacteria,COG2208@2|Bacteria	2|Bacteria	T	phosphoserine phosphatase activity	rsbU	-	3.1.3.3,4.6.1.1	ko:K01768,ko:K07315,ko:K16922	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000,ko01002,ko03021	-	-	-	CHASE2,FHA,GAF_2,HATPase_c_2,SpoIIE,Yop-YscD_cpl
SHD3_k127_505259_4	1267534.KB906757_gene899	8.863e-77	274.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
SHD3_k127_505259_5	1192034.CAP_0261	9.588e-76	259.0	COG1215@1|root,COG1215@2|Bacteria,1NDPE@1224|Proteobacteria,42PIY@68525|delta/epsilon subdivisions,2X81Z@28221|Deltaproteobacteria,2YXIU@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_5059317_1	378806.STAUR_7112	2.85e-276	886.0	COG0642@1|root,COG0784@1|root,COG1352@1|root,COG2201@1|root,COG0784@2|Bacteria,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,43C0N@68525|delta/epsilon subdivisions,2X7B9@28221|Deltaproteobacteria,2Z3EZ@29|Myxococcales	28221|Deltaproteobacteria	T	PAS domain	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS_10,PAS_4,Response_reg
SHD3_k127_5059317_9	247490.KSU1_D0867	1.658e-54	221.0	COG2203@1|root,COG3829@1|root,COG4251@1|root,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4251@2|Bacteria,2J2DQ@203682|Planctomycetes	203682|Planctomycetes	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,dCache_1
SHD3_k127_5059317_10	351160.RCIX1231	6.754e-32	147.0	COG2202@1|root,arCOG06721@1|root,arCOG06721@2157|Archaea,arCOG06918@2157|Archaea	2157|Archaea	T	Pas domain	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3,PAS_4,PAS_9,PocR
SHD3_k127_5059317_6	290397.Adeh_3529	1.071e-122	442.0	COG0642@1|root,COG0784@1|root,COG2461@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,43CCU@68525|delta/epsilon subdivisions,2X7NQ@28221|Deltaproteobacteria,2YX99@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_5059317_8	404589.Anae109_3179	2.409e-72	268.0	COG1752@1|root,COG1752@2|Bacteria,1MUM9@1224|Proteobacteria,42RSN@68525|delta/epsilon subdivisions,2WNDI@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin,cNMP_binding
SHD3_k127_5059317_2	1144275.COCOR_01446	3.704e-212	672.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,42MRU@68525|delta/epsilon subdivisions,2WIQX@28221|Deltaproteobacteria,2YZUW@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SHD3_k127_5059317_4	1144275.COCOR_01445	6.737e-136	439.0	COG0845@1|root,COG0845@2|Bacteria,1MUG6@1224|Proteobacteria,42NC1@68525|delta/epsilon subdivisions,2WMKG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
SHD3_k127_5059317_0	1144275.COCOR_01444	0.0	1472.0	COG0842@1|root,COG1129@1|root,COG0842@2|Bacteria,COG1129@2|Bacteria,1QTT9@1224|Proteobacteria,43BJ5@68525|delta/epsilon subdivisions,2X713@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	PFAM ABC transporter	-	-	-	ko:K01990,ko:K13926	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3,ABC_tran
SHD3_k127_5059317_3	1144275.COCOR_01443	2.891e-182	595.0	COG0842@1|root,COG0842@2|Bacteria,1MUIA@1224|Proteobacteria,43AEH@68525|delta/epsilon subdivisions,2WIU2@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	yhhJ	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SHD3_k127_5059317_5	448385.sce8681	3.334e-133	440.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WJKC@28221|Deltaproteobacteria,2YZGM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SHD3_k127_5059317_12	448385.sce8686	1.14e-25	108.0	2AIXE@1|root,319F2@2|Bacteria,1Q2IN@1224|Proteobacteria,4385F@68525|delta/epsilon subdivisions,2X3FF@28221|Deltaproteobacteria,2YVUW@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5059317_13	1248916.ANFY01000011_gene1164	3.77e-13	80.0	COG0642@1|root,COG2205@2|Bacteria,1MW8M@1224|Proteobacteria,2TUSJ@28211|Alphaproteobacteria,2K1K2@204457|Sphingomonadales	204457|Sphingomonadales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
SHD3_k127_5059317_7	448385.sce8690	2.546e-101	344.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_5059317_11	1254432.SCE1572_42110	6.118e-27	112.0	2EAFJ@1|root,334IY@2|Bacteria,1NA2Y@1224|Proteobacteria,42VJ1@68525|delta/epsilon subdivisions,2WRKE@28221|Deltaproteobacteria,2YVZK@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1844)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1844
SHD3_k127_5063368_11	290397.Adeh_0078	1.215e-09	65.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5063368_10	118168.MC7420_2331	7.959e-10	72.0	COG3463@1|root,COG3463@2|Bacteria,1G0WX@1117|Cyanobacteria,1H7DV@1150|Oscillatoriales	1117|Cyanobacteria	S	membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SHD3_k127_5063368_8	864702.OsccyDRAFT_0982	2.067e-19	104.0	COG3463@1|root,COG3463@2|Bacteria,1G0WX@1117|Cyanobacteria,1H7DV@1150|Oscillatoriales	1117|Cyanobacteria	S	membrane protein (DUF2079)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2079
SHD3_k127_5063368_3	1329516.JPST01000019_gene2718	2.304e-101	344.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli,27CF0@186824|Thermoactinomycetaceae	91061|Bacilli	M	Glycosyltransferase like family 2	ykcC	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
SHD3_k127_5063368_5	1128421.JAGA01000002_gene1580	9.602e-41	169.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GT87,PMT_2
SHD3_k127_5063368_9	420246.GTNG_1934	5.432e-14	78.0	COG2246@1|root,COG2246@2|Bacteria,1VFGI@1239|Firmicutes,4HZ8T@91061|Bacilli,1WGE2@129337|Geobacillus	91061|Bacilli	S	GtrA-like protein	yngA	-	-	-	-	-	-	-	-	-	-	-	GtrA
SHD3_k127_5063368_4	404589.Anae109_0092	8.768e-69	241.0	COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7I3@28221|Deltaproteobacteria,2Z24R@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_5063368_6	448385.sce6588	1.372e-28	123.0	COG4760@1|root,COG4760@2|Bacteria	2|Bacteria	D	membrane	-	-	-	ko:K06377	-	-	-	-	ko00000	-	-	-	BaxI_1
SHD3_k127_5063368_2	1192034.CAP_5889	1.032e-101	337.0	COG1521@1|root,COG1521@2|Bacteria,1MUYA@1224|Proteobacteria,42MVZ@68525|delta/epsilon subdivisions,2WJ3N@28221|Deltaproteobacteria,2YTUR@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1986	Pan_kinase
SHD3_k127_5063368_1	1192034.CAP_6313	4.144e-116	402.0	COG0652@1|root,COG0652@2|Bacteria,1R4KH@1224|Proteobacteria,42R08@68525|delta/epsilon subdivisions,2WWSG@28221|Deltaproteobacteria,2YVBS@29|Myxococcales	28221|Deltaproteobacteria	M	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	HEAT_2,Pro_isomerase
SHD3_k127_5063368_7	1192034.CAP_6314	2.514e-27	117.0	COG1434@1|root,COG1434@2|Bacteria,1RF6P@1224|Proteobacteria,43ACD@68525|delta/epsilon subdivisions,2X5S6@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
SHD3_k127_5063368_0	1192034.CAP_7811	7.251e-140	460.0	COG0617@1|root,COG0617@2|Bacteria,1MVCS@1224|Proteobacteria,42QKZ@68525|delta/epsilon subdivisions,2WJ74@28221|Deltaproteobacteria,2YU8X@29|Myxococcales	28221|Deltaproteobacteria	H	Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control	pcnB	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	PolyA_pol,PolyA_pol_RNAbd,PolyA_pol_arg_C
SHD3_k127_5073590_0	1192034.CAP_0175	5.458e-114	389.0	COG0457@1|root,COG0457@2|Bacteria,1P0DI@1224|Proteobacteria,431RN@68525|delta/epsilon subdivisions,2WWCP@28221|Deltaproteobacteria,2Z3IU@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5077493_0	1128427.KB904821_gene2462	2.695e-286	932.0	COG0642@1|root,COG1352@1|root,COG2201@1|root,COG1352@2|Bacteria,COG2201@2|Bacteria,COG2205@2|Bacteria,1G09B@1117|Cyanobacteria,1H91P@1150|Oscillatoriales	1117|Cyanobacteria	T	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,GAF,HATPase_c,HisKA,PAS_10,PAS_3,PAS_4,PAS_9,Response_reg
SHD3_k127_5077493_1	316067.Geob_3570	5.092e-204	654.0	COG0467@1|root,COG0467@2|Bacteria,1NEWW@1224|Proteobacteria,42P4F@68525|delta/epsilon subdivisions,2WJVT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Pfam:KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
SHD3_k127_5077493_3	386456.JQKN01000001_gene1698	7.321e-38	145.0	COG0526@1|root,arCOG07612@2157|Archaea,2Y43J@28890|Euryarchaeota	28890|Euryarchaeota	O	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
SHD3_k127_5077493_4	316067.Geob_3568	8.961e-32	130.0	COG4251@1|root,COG4251@2|Bacteria,1N44A@1224|Proteobacteria,431XF@68525|delta/epsilon subdivisions,2WWPK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	KaiB	-	-	-	ko:K08481	-	-	-	-	ko00000	-	-	-	KaiB
SHD3_k127_5077493_5	326427.Cagg_1364	3.605e-23	116.0	COG3920@1|root,COG3920@2|Bacteria,2GB58@200795|Chloroflexi,377AY@32061|Chloroflexia	32061|Chloroflexia	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_2,PAS
SHD3_k127_5077493_2	404589.Anae109_0529	4.868e-113	394.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria,2YZ0R@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SHD3_k127_5087077_1	663610.JQKO01000001_gene626	5.583e-25	111.0	COG3324@1|root,COG3324@2|Bacteria,1R81W@1224|Proteobacteria,2U6BE@28211|Alphaproteobacteria,3NBSY@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
SHD3_k127_5087077_0	251221.35211586	1.054e-110	370.0	COG0598@1|root,COG0598@2|Bacteria,1G1AG@1117|Cyanobacteria	1117|Cyanobacteria	P	Mediates influx of magnesium ions	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
SHD3_k127_5087077_2	290397.Adeh_3956	3.257e-19	96.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5088794_3	595460.RRSWK_00524	4.296e-32	132.0	COG1609@1|root,COG4977@1|root,COG1609@2|Bacteria,COG4977@2|Bacteria,2IXTX@203682|Planctomycetes	203682|Planctomycetes	K	Xylose operon regulatory protein	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18,Peripla_BP_3
SHD3_k127_5088794_1	518766.Rmar_0478	1.17e-111	385.0	COG3533@1|root,COG3533@2|Bacteria,4NF8W@976|Bacteroidetes	976|Bacteroidetes	C	glycosyl hydrolase of	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	DUF4986,Glyco_hydro_127
SHD3_k127_5088794_0	1408473.JHXO01000005_gene1551	2.435e-168	545.0	COG3507@1|root,COG3507@2|Bacteria,4PKXQ@976|Bacteroidetes,2FNWV@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	xynD_2	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_43
SHD3_k127_5088794_2	4787.PITG_22758T0	2.91e-109	369.0	28JQD@1|root,2QS3Q@2759|Eukaryota,3QB0C@4776|Peronosporales	4776|Peronosporales	M	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	ArabFuran-catal
SHD3_k127_5089797_3	448385.sce7823	2.839e-92	312.0	COG0812@1|root,COG0812@2|Bacteria,1MXDH@1224|Proteobacteria,42R0K@68525|delta/epsilon subdivisions,2WMTU@28221|Deltaproteobacteria,2Z309@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
SHD3_k127_5089797_15	706587.Desti_4672	6.316e-10	66.0	2EM0R@1|root,33EQ9@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5089797_2	448385.sce5122	2.252e-132	439.0	COG1715@1|root,COG1715@2|Bacteria,1QXA7@1224|Proteobacteria,438GS@68525|delta/epsilon subdivisions,2X3RM@28221|Deltaproteobacteria,2YWXV@29|Myxococcales	28221|Deltaproteobacteria	V	HB1, ASXL, restriction endonuclease HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HARE-HTH,Mrr_cat
SHD3_k127_5089797_5	448385.sce5121	1.805e-71	258.0	COG2834@1|root,COG2834@2|Bacteria,1NMTC@1224|Proteobacteria,42XC3@68525|delta/epsilon subdivisions,2WT97@28221|Deltaproteobacteria,2YWF6@29|Myxococcales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4292
SHD3_k127_5089797_7	1192034.CAP_1151	2.624e-49	186.0	COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,42U7W@68525|delta/epsilon subdivisions,2WQ9A@28221|Deltaproteobacteria,2YVEF@29|Myxococcales	28221|Deltaproteobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
SHD3_k127_5089797_8	1254432.SCE1572_31045	6.268e-48	184.0	COG0758@1|root,COG0758@2|Bacteria,1MVF6@1224|Proteobacteria,42N10@68525|delta/epsilon subdivisions,2WJI9@28221|Deltaproteobacteria,2YVFF@29|Myxococcales	28221|Deltaproteobacteria	LU	DNA recombination-mediator protein A	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
SHD3_k127_5089797_11	448385.sce2055	4.768e-19	101.0	COG3055@1|root,COG3203@1|root,COG3055@2|Bacteria,COG3203@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5089797_14	1242864.D187_006227	3.922e-10	72.0	COG2730@1|root,COG4447@1|root,COG2730@2|Bacteria,COG4447@2|Bacteria,1R5GC@1224|Proteobacteria,434P8@68525|delta/epsilon subdivisions,2WZ0H@28221|Deltaproteobacteria,2Z12C@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_5089797_9	63402.XP_003175784.1	2.261e-37	156.0	KOG1218@1|root,KOG1218@2759|Eukaryota,38F48@33154|Opisthokonta	33154|Opisthokonta	T	EB module	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5089797_1	448385.sce5114	1.082e-153	497.0	COG1206@1|root,COG1206@2|Bacteria,1MWNQ@1224|Proteobacteria,42MTS@68525|delta/epsilon subdivisions,2WJ50@28221|Deltaproteobacteria,2YU50@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs	trmFO	GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363	2.1.1.74	ko:K04094	-	-	-	-	ko00000,ko01000,ko03016,ko03036	-	-	-	GIDA
SHD3_k127_5089797_0	448385.sce3845	0.0	1015.0	COG0317@1|root,COG0317@2|Bacteria,1MU44@1224|Proteobacteria,42M6W@68525|delta/epsilon subdivisions,2WIZF@28221|Deltaproteobacteria,2YUFJ@29|Myxococcales	28221|Deltaproteobacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
SHD3_k127_5089797_17	218284.CCDN010000001_gene1975	0.0001057	49.0	2DFW2@1|root,2ZTE1@2|Bacteria,1W5BA@1239|Firmicutes,4IM45@91061|Bacilli,1ZJ3K@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5089797_12	1380355.JNIJ01000041_gene5253	5.794e-12	68.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,2U24Y@28211|Alphaproteobacteria,3JXTX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_32,rve,rve_3
SHD3_k127_5089797_4	448385.sce7736	1.745e-75	266.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_5089797_10	1038860.AXAP01000157_gene8657	4.898e-26	111.0	COG2801@1|root,COG2801@2|Bacteria,1MX69@1224|Proteobacteria,2TSIE@28211|Alphaproteobacteria,3K2DN@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve_3
SHD3_k127_5089797_13	56110.Oscil6304_1700	1.378e-10	74.0	2DV72@1|root,33UF1@2|Bacteria,1GDJA@1117|Cyanobacteria	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5093206_12	497321.C664_05061	2.712e-26	117.0	COG0731@1|root,COG0731@2|Bacteria,1QG36@1224|Proteobacteria,2VK7Z@28216|Betaproteobacteria,2KVBZ@206389|Rhodocyclales	206389|Rhodocyclales	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5093206_1	448385.sce1276	6.441e-134	438.0	COG2357@1|root,COG2357@2|Bacteria,1QYWE@1224|Proteobacteria,432GG@68525|delta/epsilon subdivisions,2WY52@28221|Deltaproteobacteria,2Z0Y8@29|Myxococcales	28221|Deltaproteobacteria	S	RelA SpoT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5093206_16	644282.Deba_1242	3.08e-17	84.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42WGE@68525|delta/epsilon subdivisions,2WRF1@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
SHD3_k127_5093206_2	448385.sce3438	9.617e-91	308.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_5093206_9	391625.PPSIR1_00085	2.406e-45	179.0	COG3712@1|root,COG3712@2|Bacteria,1PBZ9@1224|Proteobacteria,433U5@68525|delta/epsilon subdivisions,2X3GP@28221|Deltaproteobacteria,2YW0J@29|Myxococcales	28221|Deltaproteobacteria	PT	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,zf-HC2
SHD3_k127_5093206_10	391625.PPSIR1_00090	2.056e-35	143.0	COG1595@1|root,COG1595@2|Bacteria,1N4RS@1224|Proteobacteria,43E0K@68525|delta/epsilon subdivisions,2WZCJ@28221|Deltaproteobacteria,2Z1UN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5093206_8	448385.sce5860	5.142e-61	222.0	COG1595@1|root,COG1595@2|Bacteria,1R7KF@1224|Proteobacteria,4385W@68525|delta/epsilon subdivisions,2X9YP@28221|Deltaproteobacteria,2YVWM@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5093206_13	1254432.SCE1572_34890	7.207e-25	108.0	2A4YU@1|root,30TKK@2|Bacteria,1PDH1@1224|Proteobacteria,435GP@68525|delta/epsilon subdivisions,2WZU4@28221|Deltaproteobacteria,2Z2RP@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5093206_3	1192034.CAP_2507	1.449e-85	291.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P3C@68525|delta/epsilon subdivisions,2WJW1@28221|Deltaproteobacteria,2YUUB@29|Myxococcales	28221|Deltaproteobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
SHD3_k127_5093206_5	1254432.SCE1572_23540	8.764e-78	268.0	COG2935@1|root,COG2935@2|Bacteria,1MW62@1224|Proteobacteria,42N66@68525|delta/epsilon subdivisions,2WQ1W@28221|Deltaproteobacteria,2YVMR@29|Myxococcales	28221|Deltaproteobacteria	O	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate	ate	-	2.3.2.29	ko:K21420	-	-	R11547,R11548	RC00064	ko00000,ko01000	-	-	-	ATE_C,ATE_N
SHD3_k127_5093206_7	1192034.CAP_2505	2e-72	267.0	COG0745@1|root,COG1196@1|root,COG0745@2|Bacteria,COG1196@2|Bacteria,1QXA6@1224|Proteobacteria,43E4U@68525|delta/epsilon subdivisions,2X7E9@28221|Deltaproteobacteria,2YVVM@29|Myxococcales	28221|Deltaproteobacteria	DKT	Response regulator receiver domain	frzS	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_5093206_18	246197.MXAN_2752	1.35e-06	61.0	COG3170@1|root,COG4260@1|root,COG3170@2|Bacteria,COG4260@2|Bacteria,1Q3VD@1224|Proteobacteria,4343A@68525|delta/epsilon subdivisions,2X513@28221|Deltaproteobacteria,2YZYS@29|Myxococcales	28221|Deltaproteobacteria	NU	Domain of unknown function (DUF4339)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4339
SHD3_k127_5093206_6	448385.sce0037	5.725e-74	261.0	COG1496@1|root,COG1496@2|Bacteria,1MW2H@1224|Proteobacteria,42SE9@68525|delta/epsilon subdivisions,2WMQE@28221|Deltaproteobacteria,2YVJ7@29|Myxococcales	28221|Deltaproteobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
SHD3_k127_5093206_0	448385.sce0038	7.148e-137	444.0	COG0393@1|root,COG0515@1|root,COG0393@2|Bacteria,COG0515@2|Bacteria,1QA6R@1224|Proteobacteria,439IS@68525|delta/epsilon subdivisions,2X4V7@28221|Deltaproteobacteria,2YZNY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_5093206_4	1254432.SCE1572_00180	6.4e-79	273.0	COG5009@1|root,COG5009@2|Bacteria,1MU5A@1224|Proteobacteria,42MJB@68525|delta/epsilon subdivisions,2WIXF@28221|Deltaproteobacteria,2YUHY@29|Myxococcales	28221|Deltaproteobacteria	M	penicillin-binding protein	mrcA	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	iAF987.Gmet_0354	PCB_OB,Transgly,Transpeptidase
SHD3_k127_5094149_2	448385.sce7604	2.973e-35	149.0	COG3921@1|root,COG3921@2|Bacteria	2|Bacteria	S	Extensin-like protein C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
SHD3_k127_5094149_0	1291050.JAGE01000002_gene3671	6.19e-110	370.0	COG3345@1|root,COG3345@2|Bacteria,1U52C@1239|Firmicutes,25FA2@186801|Clostridia,3WJWC@541000|Ruminococcaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Dockerin_1,Melibiase_2
SHD3_k127_5094149_1	448385.sce3301	5.674e-40	159.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Lipase_GDSL_2
SHD3_k127_5094149_3	203119.Cthe_1471	5.034e-22	102.0	COG2730@1|root,COG2730@2|Bacteria,1UTVE@1239|Firmicutes,254HP@186801|Clostridia,3WR4M@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5103520_0	1192034.CAP_7704	5.696e-29	131.0	COG2340@1|root,COG2340@2|Bacteria,1Q6AW@1224|Proteobacteria,439IR@68525|delta/epsilon subdivisions,2X4V6@28221|Deltaproteobacteria,2YZNX@29|Myxococcales	28221|Deltaproteobacteria	S	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SHD3_k127_5103520_1	555088.DealDRAFT_0781	4.121e-26	113.0	COG5586@1|root,COG5586@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2293
SHD3_k127_5103520_2	1415630.U771_19005	4.474e-09	59.0	COG0625@1|root,COG0625@2|Bacteria,1NX28@1224|Proteobacteria,1RQUP@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Glutathione S-transferase	yfcF	-	2.5.1.18	ko:K00799	ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418	-	R03522,R07002,R07003,R07004,R07023,R07024,R07025,R07026,R07069,R07070,R07083,R07084,R07091,R07092,R07093,R07094,R07100,R07113,R07116,R08280,R09409,R11905	RC00004,RC00069,RC00840,RC00948,RC01704,RC01705,RC01706,RC01758,RC01759,RC01765,RC01767,RC01769,RC02243,RC02527,RC02939,RC02940,RC02942,RC02943,RC02944	ko00000,ko00001,ko01000,ko02000	1.A.12.2.2,1.A.12.3.2	-	-	GST_C_4,GST_N,GST_N_3
SHD3_k127_5103789_3	1538295.JY96_10180	1.069e-07	61.0	2BX6S@1|root,3386D@2|Bacteria,1N91D@1224|Proteobacteria,2VX8C@28216|Betaproteobacteria,1KMKH@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	Protein of unknown function (DUF1439)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1439
SHD3_k127_5103789_1	1192034.CAP_7489	1.892e-176	597.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE,DUF4215,RCC1,RCC1_2
SHD3_k127_5103789_0	1192034.CAP_7488	1.32e-180	618.0	COG5184@1|root,COG5184@2|Bacteria,1P1C6@1224|Proteobacteria,4310A@68525|delta/epsilon subdivisions,2WWWF@28221|Deltaproteobacteria,2Z029@29|Myxococcales	28221|Deltaproteobacteria	DZ	Putative metal-binding motif	-	-	-	-	-	-	-	-	-	-	-	-	Cu-binding_MopE
SHD3_k127_5103789_4	1380393.JHVP01000013_gene3424	0.0004053	53.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_5103789_2	871968.DESME_03075	9.318e-28	119.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	DUF11
SHD3_k127_5111602_0	945713.IALB_2594	1.783e-208	673.0	COG1472@1|root,COG1472@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
SHD3_k127_5111602_2	448385.sce1380	1.878e-17	96.0	COG0515@1|root,COG0515@2|Bacteria,1P2EB@1224|Proteobacteria	1224|Proteobacteria	KLT	Family membership	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_5111602_4	706439.HMPREF9057_02225	1.025e-05	51.0	2AS1K@1|root,31HE1@2|Bacteria,2HM28@201174|Actinobacteria,4D68E@85005|Actinomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5111602_1	1120941.AUBL01000034_gene2176	1.124e-22	105.0	COG1848@1|root,COG1848@2|Bacteria,2HMSF@201174|Actinobacteria,4D7GW@85005|Actinomycetales	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5111602_3	1038860.AXAP01000042_gene115	3.067e-15	83.0	COG4992@1|root,COG4992@2|Bacteria,1MV3C@1224|Proteobacteria,2U0HZ@28211|Alphaproteobacteria,3JTHX@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	Aminotransferase class-III	MA20_13060	GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
SHD3_k127_5115562_1	1192034.CAP_1274	5.546e-128	426.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
SHD3_k127_5115562_2	62928.azo3774	7.655e-46	181.0	COG0515@1|root,COG0515@2|Bacteria,1P64D@1224|Proteobacteria	1224|Proteobacteria	KLT	serine threonine protein kinase	pkn9	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_5115562_0	448385.sce5126	2.048e-197	639.0	2AIV6@1|root,319CD@2|Bacteria,1Q2BD@1224|Proteobacteria,437XV@68525|delta/epsilon subdivisions,2X37S@28221|Deltaproteobacteria,2YUR7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5125345_3	290397.Adeh_4078	1.363e-45	175.0	COG3884@1|root,COG3884@2|Bacteria,1NBT0@1224|Proteobacteria,42W3W@68525|delta/epsilon subdivisions,2WR9F@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
SHD3_k127_5125345_6	1193181.BN10_160001	1.014e-07	55.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4FJAV@85021|Intrasporangiaceae	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	ko:K07493	-	-	-	-	ko00000	-	-	-	Transposase_mut
SHD3_k127_5125345_4	1304880.JAGB01000002_gene1556	2.472e-31	126.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
SHD3_k127_5125345_7	215803.DB30_4802	0.0001812	47.0	COG1506@1|root,COG1506@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PA14
SHD3_k127_5125345_0	448385.sce0368	1.317e-226	724.0	COG0247@1|root,COG0247@2|Bacteria,1MUMH@1224|Proteobacteria,42MIV@68525|delta/epsilon subdivisions,2WJ5X@28221|Deltaproteobacteria,2YUAI@29|Myxococcales	28221|Deltaproteobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8,Fer4_9
SHD3_k127_5125345_2	448385.sce0369	2.049e-57	206.0	COG0566@1|root,COG0566@2|Bacteria,1MWBE@1224|Proteobacteria,42R8D@68525|delta/epsilon subdivisions,2WN83@28221|Deltaproteobacteria,2YVI3@29|Myxococcales	28221|Deltaproteobacteria	J	SpoU rRNA Methylase family	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
SHD3_k127_5125345_1	1254432.SCE1572_51515	9.346e-71	246.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,HEAT_PBS,NB-ARC,cNMP_binding
SHD3_k127_5139747_1	706587.Desti_2376	4.196e-44	171.0	COG1180@1|root,COG1180@2|Bacteria,1QJHU@1224|Proteobacteria,42R2E@68525|delta/epsilon subdivisions,2WMYN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	TIGRFAM glycyl-radical enzyme activating protein family	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
SHD3_k127_5139747_0	706587.Desti_2378	2.837e-169	552.0	COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,42M5J@68525|delta/epsilon subdivisions,2WJAK@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	formate C-acetyltransferase glycine radical	-	-	-	-	-	-	-	-	-	-	-	-	Gly_radical,PFL-like
SHD3_k127_5144725_2	1254432.SCE1572_16220	1.289e-76	263.0	2DQDU@1|root,3366T@2|Bacteria	2|Bacteria	S	Thaumatin family	-	-	-	-	-	-	-	-	-	-	-	-	Thaumatin
SHD3_k127_5144725_1	448385.sce3274	2.394e-157	508.0	2A4SW@1|root,30TEA@2|Bacteria,1PD78@1224|Proteobacteria,438UI@68525|delta/epsilon subdivisions,2X40J@28221|Deltaproteobacteria,2YXT8@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2403
SHD3_k127_5144725_0	1121007.AUML01000046_gene4058	8.969e-190	613.0	COG0520@1|root,COG0520@2|Bacteria,4NDUB@976|Bacteroidetes,1HWSI@117743|Flavobacteriia,2YGVA@290174|Aquimarina	976|Bacteroidetes	E	Beta-eliminating lyase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
SHD3_k127_5144725_3	448385.sce2918	2.212e-60	234.0	COG1716@1|root,COG1716@2|Bacteria,1NEW5@1224|Proteobacteria,42VUF@68525|delta/epsilon subdivisions,2WRV9@28221|Deltaproteobacteria,2YV34@29|Myxococcales	28221|Deltaproteobacteria	T	FHA domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,TonB_C,Yop-YscD_cpl
SHD3_k127_5144725_4	794903.OPIT5_09350	3.288e-34	144.0	COG2207@1|root,COG2207@2|Bacteria,46Y3Q@74201|Verrucomicrobia,3K8VU@414999|Opitutae	414999|Opitutae	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
SHD3_k127_5144725_5	448385.sce6659	6.227e-25	111.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5154675_10	1487953.JMKF01000077_gene4059	1.831e-27	129.0	COG1357@1|root,COG1357@2|Bacteria,1G0KS@1117|Cyanobacteria,1H6Y2@1150|Oscillatoriales	1117|Cyanobacteria	S	PFAM Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
SHD3_k127_5154675_15	1089550.ATTH01000001_gene1816	9.892e-05	51.0	COG1664@1|root,COG1664@2|Bacteria,4NUZA@976|Bacteroidetes,1FJH9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SHD3_k127_5154675_12	448385.sce2986	2.242e-11	77.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce2986|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5154675_9	448385.sce5502	3.327e-30	134.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MZ25@1224|Proteobacteria,42PUT@68525|delta/epsilon subdivisions,2WKN0@28221|Deltaproteobacteria,2YVT8@29|Myxococcales	28221|Deltaproteobacteria	KLT	Sulfatase-modifying factor enzyme 1	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	FGE-sulfatase,Pkinase
SHD3_k127_5154675_11	448385.sce2186	1.751e-19	101.0	COG1729@1|root,COG1729@2|Bacteria,1PYP2@1224|Proteobacteria,435GR@68525|delta/epsilon subdivisions,2WZU6@28221|Deltaproteobacteria,2Z2RR@29|Myxococcales	28221|Deltaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR
SHD3_k127_5154675_7	448385.sce2185	4.007e-48	181.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5154675_1	1173023.KE650771_gene104	1.054e-184	603.0	COG0659@1|root,COG0659@2|Bacteria,1G1CM@1117|Cyanobacteria,1JGWV@1189|Stigonemataceae	1117|Cyanobacteria	P	secondary active sulfate transmembrane transporter activity	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	-
SHD3_k127_5154675_6	880073.Calab_2806	2.131e-48	190.0	COG2199@1|root,COG3706@2|Bacteria,2NPJ3@2323|unclassified Bacteria	2|Bacteria	T	diguanylate cyclase	-	-	2.7.7.65	ko:K02488	ko02020,ko04112,map02020,map04112	M00511	R08057	-	ko00000,ko00001,ko00002,ko01000,ko02022	-	-	-	EAL,GAF,GAF_2,GGDEF,HisKA_7TM,PAS_4,PAS_9,PocR,Response_reg
SHD3_k127_5154675_0	404589.Anae109_0189	0.0	1230.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1PKG6@1224|Proteobacteria,42MY4@68525|delta/epsilon subdivisions,2WJFI@28221|Deltaproteobacteria,2YVGM@29|Myxococcales	28221|Deltaproteobacteria	I	CoA-substrate-specific enzyme activase	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229
SHD3_k127_5154675_4	448385.sce4313	3.561e-70	260.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA
SHD3_k127_5154675_5	335543.Sfum_2242	6.836e-50	197.0	COG1807@1|root,COG1807@2|Bacteria,1NTFE@1224|Proteobacteria,42Z1W@68525|delta/epsilon subdivisions,2WTMJ@28221|Deltaproteobacteria,2MS6C@213462|Syntrophobacterales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_5154675_8	1183438.GKIL_3078	2.77e-37	161.0	COG1807@1|root,COG1807@2|Bacteria,1GCPV@1117|Cyanobacteria	1117|Cyanobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_5154675_14	411476.BACOVA_03372	1.125e-05	58.0	2DKZS@1|root,311B0@2|Bacteria,4NQ1B@976|Bacteroidetes,2FS9G@200643|Bacteroidia	976|Bacteroidetes	S	Fimbrillin-like	-	-	-	-	-	-	-	-	-	-	-	-	Mfa_like_1
SHD3_k127_5154675_13	51453.EGR45568	3.586e-08	64.0	2E9CW@1|root,2SFRC@2759|Eukaryota,3A7JQ@33154|Opisthokonta,3P6G0@4751|Fungi,3RN3S@4890|Ascomycota,21F69@147550|Sordariomycetes,3TNER@5125|Hypocreales,3TYF7@5129|Hypocreaceae	4751|Fungi	S	Pfam:PA14_2	-	-	3.2.1.4	ko:K01179,ko:K10352	ko00500,ko01100,ko04530,map00500,map01100,map04530	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000,ko04147,ko04812	-	GH5,GH9	-	Cellulase,GLEYA,Ricin_B_lectin
SHD3_k127_5154675_3	1192034.CAP_4442	2.168e-92	330.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_4442|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5156701_10	1121430.JMLG01000002_gene1059	5.671e-14	79.0	COG1032@1|root,COG1032@2|Bacteria,1TRZA@1239|Firmicutes,24B00@186801|Clostridia,263EX@186807|Peptococcaceae	186801|Clostridia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_5156701_11	452637.Oter_3544	1.601e-08	61.0	COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	ko:K00412	ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016	M00151,M00152	-	-	ko00000,ko00001,ko00002,ko03029	-	-	-	Cytochrom_B_C,Cytochrom_B_N_2,Cytochrome_B,Cytochrome_CBB3
SHD3_k127_5156701_1	1123073.KB899242_gene1315	2.458e-114	383.0	COG4242@1|root,COG4242@2|Bacteria,1R5TW@1224|Proteobacteria,1RYMR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	PQ	Belongs to the peptidase S51 family	-	-	-	-	-	-	-	-	-	-	-	-	PPC,Peptidase_S51
SHD3_k127_5156701_7	1173020.Cha6605_4360	2.259e-38	155.0	COG2859@1|root,COG2859@2|Bacteria,1G4NY@1117|Cyanobacteria	1117|Cyanobacteria	S	periplasmic protein	-	-	-	ko:K09797	-	-	-	-	ko00000	-	-	-	SIMPL
SHD3_k127_5156701_3	1121952.ATXT01000014_gene1445	1.285e-75	261.0	arCOG07343@1|root,326WF@2|Bacteria,2GZK1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5156701_0	96561.Dole_1401	9.042e-190	600.0	COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,42M67@68525|delta/epsilon subdivisions,2WJQX@28221|Deltaproteobacteria,2MIZT@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.48,4.4.1.8	ko:K01739,ko:K01760	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00782,R00999,R01286,R01288,R02408,R02508,R03217,R03260,R04941,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00382,RC00420,RC00488,RC00710,RC01245,RC02303,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
SHD3_k127_5156701_12	324057.Pjdr2_0972	1.987e-05	55.0	COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4IQWI@91061|Bacilli,274WM@186822|Paenibacillaceae	91061|Bacilli	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SHD3_k127_5156701_9	1440774.Y900_018065	6.069e-25	119.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria,235P4@1762|Mycobacteriaceae	201174|Actinobacteria	C	Radical SAM	pqqE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_5156701_6	1038859.AXAU01000001_gene3168	1.488e-40	160.0	COG0463@1|root,COG0463@2|Bacteria,1QTWH@1224|Proteobacteria,2TRNC@28211|Alphaproteobacteria,3JXZY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
SHD3_k127_5156701_13	1121017.AUFG01000006_gene1147	6.702e-05	52.0	COG2456@1|root,COG2456@2|Bacteria,2GQTD@201174|Actinobacteria,4FH2H@85021|Intrasporangiaceae	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
SHD3_k127_5156701_4	111780.Sta7437_1417	6.378e-74	267.0	28H6C@1|root,2Z7IV@2|Bacteria,1G3DU@1117|Cyanobacteria,3VHK6@52604|Pleurocapsales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5156701_2	1123261.AXDW01000001_gene1058	2.458e-93	319.0	COG0451@1|root,COG0451@2|Bacteria,1MW32@1224|Proteobacteria,1SYQK@1236|Gammaproteobacteria,1X462@135614|Xanthomonadales	135614|Xanthomonadales	M	Male sterility protein	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SHD3_k127_5156701_5	211165.AJLN01000096_gene5033	2.852e-58	209.0	COG0364@1|root,COG0364@2|Bacteria,1GI0D@1117|Cyanobacteria,1JJHW@1189|Stigonemataceae	1117|Cyanobacteria	G	Glucose-6-phosphate dehydrogenase, NAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	G6PD_C,G6PD_N
SHD3_k127_5163988_10	290397.Adeh_0078	3.278e-42	164.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5163988_11	1254432.SCE1572_42930	2.91e-34	141.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	5.4.99.28,5.4.99.29	ko:K06177,ko:K07052,ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03009,ko03016	3.A.1.115	-	-	Abi
SHD3_k127_5163988_2	1254432.SCE1572_42935	7.754e-140	459.0	COG0452@1|root,COG0452@2|Bacteria,1MVQP@1224|Proteobacteria,42NIG@68525|delta/epsilon subdivisions,2WIR1@28221|Deltaproteobacteria,2YUKH@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
SHD3_k127_5163988_6	502025.Hoch_6056	3.157e-76	268.0	COG0515@1|root,COG0515@2|Bacteria,1Q31E@1224|Proteobacteria,438RJ@68525|delta/epsilon subdivisions,2X991@28221|Deltaproteobacteria,2YXKM@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_5163988_5	1192034.CAP_0302	2.057e-102	338.0	COG0639@1|root,COG0639@2|Bacteria	2|Bacteria	T	phosphoprotein phosphatase activity	prp1	-	3.1.3.16	ko:K07313	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
SHD3_k127_5163988_1	404589.Anae109_2880	1.94e-211	698.0	COG4935@1|root,COG4935@2|Bacteria,1QZT5@1224|Proteobacteria,42YUM@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5163988_9	1047013.AQSP01000009_gene2603	2.135e-42	162.0	2DMID@1|root,32RSF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii,DUF2204
SHD3_k127_5163988_0	1192034.CAP_2185	3.463e-261	870.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HYR,HtaA,Neocarzinostat
SHD3_k127_5163988_8	886293.Sinac_0689	5.329e-70	243.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	ybaK	-	-	ko:K03976,ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
SHD3_k127_5163988_13	1254432.SCE1572_51220	7.354e-28	124.0	COG1716@1|root,COG1716@2|Bacteria,1PFN8@1224|Proteobacteria,435DQ@68525|delta/epsilon subdivisions,2WZR8@28221|Deltaproteobacteria,2Z2JZ@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SHD3_k127_5163988_7	1192034.CAP_4568	7.757e-71	258.0	COG0515@1|root,COG0515@2|Bacteria,1Q2R6@1224|Proteobacteria,433VB@68525|delta/epsilon subdivisions,2X3MY@28221|Deltaproteobacteria,2YWK6@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_5163988_3	1089548.KI783301_gene1817	2.482e-113	377.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli,3WF4J@539002|Bacillales incertae sedis	91061|Bacilli	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_5163988_4	1163617.SCD_n00016	2.139e-105	349.0	COG1432@1|root,COG1432@2|Bacteria,1MX5C@1224|Proteobacteria,2VK44@28216|Betaproteobacteria	28216|Betaproteobacteria	NU	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
SHD3_k127_5173330_3	448385.sce0526	1.379e-175	557.0	COG1034@1|root,COG1034@2|Bacteria,1P8MN@1224|Proteobacteria,42PT5@68525|delta/epsilon subdivisions,2WKMJ@28221|Deltaproteobacteria,2YU8F@29|Myxococcales	28221|Deltaproteobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
SHD3_k127_5173330_2	1192034.CAP_0604	5.001e-198	623.0	COG0649@1|root,COG0649@2|Bacteria,1MVIN@1224|Proteobacteria,42M9G@68525|delta/epsilon subdivisions,2WIS7@28221|Deltaproteobacteria,2YU4Q@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944	1.6.5.3	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa,Complex1_49kDa
SHD3_k127_5173330_10	1254432.SCE1572_03655	4.776e-65	229.0	COG0852@1|root,COG0852@2|Bacteria,1MX4B@1224|Proteobacteria,42NAR@68525|delta/epsilon subdivisions,2WQB1@28221|Deltaproteobacteria,2YVJM@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3353	Complex1_30kDa
SHD3_k127_5173330_8	1254432.SCE1572_03650	7.48e-80	273.0	COG0377@1|root,COG0377@2|Bacteria,1MUI2@1224|Proteobacteria,42MDJ@68525|delta/epsilon subdivisions,2WN9U@28221|Deltaproteobacteria,2YUX6@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iAF987.Gmet_3354	Oxidored_q6
SHD3_k127_5173330_13	1192034.CAP_0601	1.89e-38	147.0	COG0838@1|root,COG0838@2|Bacteria,1RGUT@1224|Proteobacteria,42UPV@68525|delta/epsilon subdivisions,2WQB6@28221|Deltaproteobacteria,2YVS6@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
SHD3_k127_5173330_9	452637.Oter_1058	1.424e-77	265.0	COG0655@1|root,COG0655@2|Bacteria	2|Bacteria	S	NAD(P)H dehydrogenase (quinone) activity	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SHD3_k127_5173330_7	338963.Pcar_0322	1.077e-87	308.0	COG1194@1|root,COG1194@2|Bacteria,1MUD4@1224|Proteobacteria,42PDR@68525|delta/epsilon subdivisions,2WJ60@28221|Deltaproteobacteria,43S8C@69541|Desulfuromonadales	28221|Deltaproteobacteria	L	NUDIX domain	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4
SHD3_k127_5173330_0	472759.Nhal_2900	0.0	1079.0	COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,1WWE0@135613|Chromatiales	135613|Chromatiales	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	-	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
SHD3_k127_5173330_6	1254432.SCE1572_43825	2.395e-122	417.0	COG1408@1|root,COG1408@2|Bacteria,1MUH5@1224|Proteobacteria,42N75@68525|delta/epsilon subdivisions,2WKJY@28221|Deltaproteobacteria,2Z2YT@29|Myxococcales	28221|Deltaproteobacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
SHD3_k127_5173330_11	448385.sce4032	4.096e-50	199.0	COG2304@1|root,COG2304@2|Bacteria,1PBY8@1224|Proteobacteria,4386F@68525|delta/epsilon subdivisions,2X3GC@28221|Deltaproteobacteria,2YVZ2@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor (vWF) type A domain	cglB	-	-	-	-	-	-	-	-	-	-	-	VWA
SHD3_k127_5173330_16	1123401.JHYQ01000021_gene1015	3.915e-11	67.0	COG0864@1|root,COG0864@2|Bacteria,1N84E@1224|Proteobacteria	1224|Proteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	RHH_1
SHD3_k127_5173330_14	1123401.JHYQ01000021_gene1016	1.902e-28	119.0	COG2337@1|root,COG2337@2|Bacteria,1N1DE@1224|Proteobacteria	1224|Proteobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SHD3_k127_5173330_5	290397.Adeh_0254	1.037e-126	421.0	COG0707@1|root,COG0707@2|Bacteria	2|Bacteria	M	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	-	-	-	ko:K12583	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_tran_28_C,Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
SHD3_k127_5173330_15	665571.STHERM_c19380	3.79e-19	98.0	COG3920@1|root,COG5002@1|root,COG3920@2|Bacteria,COG5002@2|Bacteria	2|Bacteria	T	protein histidine kinase activity	exsG	-	-	-	-	-	-	-	-	-	-	-	GAF_2,GGDEF,HATPase_c,HATPase_c_2,HWE_HK,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SpoIIE
SHD3_k127_5173330_1	1192034.CAP_0657	6.452e-200	644.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,1MV4K@1224|Proteobacteria,42N93@68525|delta/epsilon subdivisions,2WJ9N@28221|Deltaproteobacteria,2YU58@29|Myxococcales	28221|Deltaproteobacteria	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
SHD3_k127_5173330_17	404589.Anae109_0027	2.41e-09	59.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PocR,Response_reg,RsbRD_N
SHD3_k127_5173764_3	13689.BV96_02976	1.033e-11	75.0	COG2159@1|root,COG2159@2|Bacteria,1R5PG@1224|Proteobacteria,2U2G9@28211|Alphaproteobacteria,2K1BU@204457|Sphingomonadales	204457|Sphingomonadales	S	PFAM amidohydrolase 2	-	-	4.1.1.45	ko:K03392	ko00380,ko01100,map00380,map01100	M00038	R04323	RC00779	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_2
SHD3_k127_5173764_1	886293.Sinac_2842	1.435e-38	154.0	COG2091@1|root,COG2091@2|Bacteria,2J06Q@203682|Planctomycetes	203682|Planctomycetes	H	Belongs to the P-Pant transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SHD3_k127_5173764_0	397288.C806_04479	6.708e-129	431.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,27JJP@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SHD3_k127_5179506_3	448385.sce3942	5.143e-100	334.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YWMB@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_5179506_9	247490.KSU1_D0857	2.413e-26	121.0	2F0IU@1|root,33TMI@2|Bacteria,2J1V2@203682|Planctomycetes	203682|Planctomycetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5179506_6	237368.SCABRO_00305	2.584e-60	216.0	COG0755@1|root,COG0755@2|Bacteria,2J2E5@203682|Planctomycetes	203682|Planctomycetes	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
SHD3_k127_5179506_4	497964.CfE428DRAFT_4938	1.491e-92	316.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia	74201|Verrucomicrobia	C	DRTGG domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
SHD3_k127_5179506_0	1184607.AUCHE_22_00900	9.713e-167	536.0	COG0372@1|root,COG0372@2|Bacteria,2GSH4@201174|Actinobacteria,4F62W@85018|Dermatophilaceae	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SHD3_k127_5179506_10	1121403.AUCV01000002_gene539	1.895e-14	80.0	COG1146@1|root,COG1146@2|Bacteria,1NJJD@1224|Proteobacteria,42VKY@68525|delta/epsilon subdivisions,2WRXE@28221|Deltaproteobacteria,2MKYB@213118|Desulfobacterales	28221|Deltaproteobacteria	C	4Fe-4S ferredoxin, iron-sulfur binding	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_7
SHD3_k127_5179506_1	335543.Sfum_1166	1.81e-133	439.0	COG0674@1|root,COG0674@2|Bacteria,1NBSJ@1224|Proteobacteria,42MS1@68525|delta/epsilon subdivisions,2WJ97@28221|Deltaproteobacteria,2MQWC@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	oxidoreductase, alpha subunit	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
SHD3_k127_5179506_5	644282.Deba_2850	4.672e-91	309.0	COG1013@1|root,COG1013@2|Bacteria,1R5BF@1224|Proteobacteria,42MD3@68525|delta/epsilon subdivisions,2WJQ0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Thiamine pyrophosphate	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
SHD3_k127_5179506_7	335543.Sfum_1168	2.849e-41	161.0	COG1014@1|root,COG1014@2|Bacteria,1RAQ4@1224|Proteobacteria,43BEE@68525|delta/epsilon subdivisions,2WN0D@28221|Deltaproteobacteria,2MRMB@213462|Syntrophobacterales	28221|Deltaproteobacteria	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	korC	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
SHD3_k127_5179506_8	1121405.dsmv_2440	7.713e-35	141.0	2CAZH@1|root,2Z7RU@2|Bacteria,1RBDC@1224|Proteobacteria,42SC7@68525|delta/epsilon subdivisions,2WP8S@28221|Deltaproteobacteria,2MJFJ@213118|Desulfobacterales	28221|Deltaproteobacteria	C	TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family	frdC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SHD3_k127_5179506_2	880070.Cycma_0904	2.69e-131	424.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SHD3_k127_5191324_6	448385.sce1829	8.651e-69	252.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2Z31E@29|Myxococcales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_5191324_10	3702.AT4G33730.1	6.527e-29	122.0	COG2340@1|root,KOG3017@2759|Eukaryota,37UH8@33090|Viridiplantae,3GIM9@35493|Streptophyta,3I07J@3699|Brassicales	35493|Streptophyta	S	Belongs to the CRISP family	-	-	-	ko:K13449	ko04016,ko04075,ko04626,map04016,map04075,map04626	-	-	-	ko00000,ko00001	-	-	-	CAP
SHD3_k127_5191324_7	448385.sce7194	4.472e-67	245.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce7194|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5191324_5	502025.Hoch_6519	3.573e-72	254.0	COG1230@1|root,COG1230@2|Bacteria,1MVQB@1224|Proteobacteria,42MJ0@68525|delta/epsilon subdivisions,2WKKK@28221|Deltaproteobacteria,2Z2YM@29|Myxococcales	28221|Deltaproteobacteria	P	Cation efflux family	dmeF	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
SHD3_k127_5191324_13	671143.DAMO_3023	5.343e-13	76.0	COG1848@1|root,COG1848@2|Bacteria	2|Bacteria	G	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005576	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
SHD3_k127_5191324_2	290397.Adeh_1573	8.797e-207	658.0	COG0477@1|root,COG0477@2|Bacteria,1RGPN@1224|Proteobacteria,43BMI@68525|delta/epsilon subdivisions,2X6ZQ@28221|Deltaproteobacteria,2Z3FD@29|Myxococcales	28221|Deltaproteobacteria	P	Major Facilitator Superfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SHD3_k127_5191324_4	215803.DB30_6919	5.369e-102	353.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42S77@68525|delta/epsilon subdivisions,2X5PF@28221|Deltaproteobacteria,2YXJB@29|Myxococcales	28221|Deltaproteobacteria	V	Biotin-lipoyl like	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_D23
SHD3_k127_5191324_11	765913.ThidrDRAFT_2439	1.346e-23	109.0	COG3861@1|root,COG3861@2|Bacteria,1RD6Y@1224|Proteobacteria,1S4FS@1236|Gammaproteobacteria,1WYS2@135613|Chromatiales	135613|Chromatiales	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PRC
SHD3_k127_5191324_16	1282362.AEAC466_07890	1.574e-05	49.0	COG3315@1|root,COG3315@2|Bacteria,1RG18@1224|Proteobacteria,2VFMW@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	LCM
SHD3_k127_5191324_1	519989.ECTPHS_11782	1.963e-240	769.0	COG1743@1|root,COG1743@2|Bacteria,1P7I6@1224|Proteobacteria,1RMB6@1236|Gammaproteobacteria,1WXFZ@135613|Chromatiales	135613|Chromatiales	L	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SHD3_k127_5191324_0	215803.DB30_5796	1.102e-283	890.0	COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,42M2R@68525|delta/epsilon subdivisions,2WJ4J@28221|Deltaproteobacteria,2YTUI@29|Myxococcales	28221|Deltaproteobacteria	P	copper-translocating P-type ATPase	copF	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
SHD3_k127_5191324_8	1297742.A176_03329	1.196e-54	205.0	COG1595@1|root,COG1595@2|Bacteria,1RBM4@1224|Proteobacteria,42S7N@68525|delta/epsilon subdivisions,2X3DW@28221|Deltaproteobacteria,2YUWD@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5191324_9	1121405.dsmv_1931	6.158e-40	156.0	COG3945@1|root,COG3945@2|Bacteria,1RG8J@1224|Proteobacteria,42S6P@68525|delta/epsilon subdivisions,2WNYW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
SHD3_k127_5191324_12	1286171.EAL2_808p00350	1.469e-18	90.0	COG1985@1|root,COG1985@2|Bacteria,1U525@1239|Firmicutes,259XK@186801|Clostridia,25Z3Z@186806|Eubacteriaceae	186801|Clostridia	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SHD3_k127_5193269_5	1254432.SCE1572_25715	9.012e-63	227.0	COG5549@1|root,COG5549@2|Bacteria,1PBXR@1224|Proteobacteria,43864@68525|delta/epsilon subdivisions,2X0VV@28221|Deltaproteobacteria,2YVXH@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SHD3_k127_5193269_7	391625.PPSIR1_34402	1.336e-22	106.0	COG1024@1|root,COG1024@2|Bacteria,1MVEC@1224|Proteobacteria,4385B@68525|delta/epsilon subdivisions,2X9XY@28221|Deltaproteobacteria,2YVU8@29|Myxococcales	28221|Deltaproteobacteria	I	enoyl-CoA hydratase	-	-	-	ko:K15312	-	-	-	-	ko00000,ko01008	-	-	-	ECH_1
SHD3_k127_5193269_4	1297742.A176_02168	2.547e-95	342.0	COG1506@1|root,COG1506@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PA14
SHD3_k127_5193269_0	1123253.AUBD01000002_gene1165	1.5e-265	833.0	COG1505@1|root,COG1505@2|Bacteria,1NZ7N@1224|Proteobacteria,1T1KJ@1236|Gammaproteobacteria,1X478@135614|Xanthomonadales	135614|Xanthomonadales	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
SHD3_k127_5193269_3	686340.Metal_0215	3.289e-114	389.0	2DUCG@1|root,33PYM@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5193269_1	335543.Sfum_1906	2.138e-126	428.0	COG2204@1|root,COG4191@1|root,COG2204@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42MFW@68525|delta/epsilon subdivisions,2WJSJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,PAS_9,Response_reg
SHD3_k127_5193269_6	1245469.S58_20290	2.948e-36	149.0	COG0262@1|root,COG0262@2|Bacteria,1RH0P@1224|Proteobacteria,2U9GC@28211|Alphaproteobacteria,3JQWH@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
SHD3_k127_5193269_2	879212.DespoDRAFT_02545	7.854e-124	401.0	COG0207@1|root,COG0207@2|Bacteria,1MUBD@1224|Proteobacteria,42PY3@68525|delta/epsilon subdivisions,2WV23@28221|Deltaproteobacteria	28221|Deltaproteobacteria	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	-	-	-	-	-	-	-	-	-	-	Thymidylat_synt
SHD3_k127_5198535_2	502025.Hoch_1787	8.325e-55	211.0	COG0671@1|root,COG0671@2|Bacteria,1RIRR@1224|Proteobacteria,42X79@68525|delta/epsilon subdivisions,2WSVG@28221|Deltaproteobacteria,2Z1Q2@29|Myxococcales	28221|Deltaproteobacteria	I	Acid phosphatase homologues	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
SHD3_k127_5198535_0	1191523.MROS_2102	2.142e-160	523.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2,MFS_3
SHD3_k127_5198535_1	1173263.Syn7502_00051	1.535e-87	297.0	COG0664@1|root,COG4420@1|root,COG0664@2|Bacteria,COG4420@2|Bacteria,1G2QW@1117|Cyanobacteria,1H1J5@1129|Synechococcus	1117|Cyanobacteria	CT	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2,cNMP_binding
SHD3_k127_5198535_3	443144.GM21_3357	3.05e-41	160.0	COG2804@1|root,COG2804@2|Bacteria,1MU7V@1224|Proteobacteria,42M51@68525|delta/epsilon subdivisions,2WIVD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NU	General secretory system II, protein E domain protein	pulE-3	-	-	ko:K02454	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	T2SSE,T2SSE_N
SHD3_k127_5210620_3	1192034.CAP_4023	1.668e-07	57.0	COG0845@1|root,COG0845@2|Bacteria,1MU8D@1224|Proteobacteria,42NVA@68525|delta/epsilon subdivisions,2WMQK@28221|Deltaproteobacteria,2YWS4@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
SHD3_k127_5210620_2	335543.Sfum_1360	7.158e-93	319.0	COG0635@1|root,COG0635@2|Bacteria,1MU76@1224|Proteobacteria,42NGU@68525|delta/epsilon subdivisions,2WIM5@28221|Deltaproteobacteria,2MQ6W@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Involved in the biosynthesis of porphyrin-containing compound	-	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
SHD3_k127_5210620_0	909663.KI867150_gene2669	1.998e-284	884.0	COG0481@1|root,COG0481@2|Bacteria,1MVZA@1224|Proteobacteria,42M3D@68525|delta/epsilon subdivisions,2WJEA@28221|Deltaproteobacteria,2MQ6G@213462|Syntrophobacterales	28221|Deltaproteobacteria	J	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C
SHD3_k127_5210620_1	448385.sce7999	9.248e-108	357.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1RGWC@1224|Proteobacteria,42N4Z@68525|delta/epsilon subdivisions,2WIKW@28221|Deltaproteobacteria,2Z30B@29|Myxococcales	28221|Deltaproteobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	-	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
SHD3_k127_5217108_6	5762.XP_002670031.1	3.843e-29	134.0	2EUNG@1|root,2SWSM@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5217108_5	1313172.YM304_06760	8.009e-32	141.0	2DBF7@1|root,2Z8X0@2|Bacteria,2I0F0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SHD3_k127_5217108_1	765911.Thivi_4128	3.903e-152	495.0	COG0076@1|root,COG0076@2|Bacteria,1MWUX@1224|Proteobacteria,1RQ8G@1236|Gammaproteobacteria,1WZ19@135613|Chromatiales	135613|Chromatiales	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.86	ko:K13745	ko00260,ko01120,map00260,map01120	-	R07650	RC00299	ko00000,ko00001,ko01000	-	-	-	Pyridoxal_deC
SHD3_k127_5217108_7	459349.CLOAM0012	1.364e-12	77.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SHD3_k127_5217108_3	1123519.PSJM300_17900	8.171e-48	179.0	COG2020@1|root,COG2020@2|Bacteria,1N3YJ@1224|Proteobacteria,1SGBM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	O	Phospholipid methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SHD3_k127_5217108_0	59538.XP_005975636.1	4.979e-159	513.0	KOG2366@1|root,KOG2366@2759|Eukaryota,38EIP@33154|Opisthokonta,3BAJ5@33208|Metazoa,3CSQH@33213|Bilateria,47YZ9@7711|Chordata	33208|Metazoa	G	alpha-galactosidase activity	-	-	3.2.1.22,3.2.1.49	ko:K01189,ko:K01204,ko:K07407	ko00052,ko00561,ko00600,ko00603,ko04142,map00052,map00561,map00600,map00603,map04142	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R05966,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,Melibiase_2_C
SHD3_k127_5217108_2	398512.JQKC01000006_gene743	7.899e-90	319.0	COG2006@1|root,COG2133@1|root,COG2006@2|Bacteria,COG2133@2|Bacteria	2|Bacteria	G	pyrroloquinoline quinone binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5217108_4	529818.AMSG_02461T0	2.453e-47	190.0	KOG1215@1|root,KOG3607@1|root,KOG4348@1|root,KOG1215@2759|Eukaryota,KOG3607@2759|Eukaryota,KOG4348@2759|Eukaryota	2759|Eukaryota	S	negative regulation of transforming growth factor beta1 production	KMT2D	GO:0000003,GO:0001654,GO:0001667,GO:0001745,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005938,GO:0006928,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007423,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010564,GO:0010631,GO:0016020,GO:0016043,GO:0016477,GO:0017124,GO:0019904,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030029,GO:0030036,GO:0030100,GO:0030154,GO:0030496,GO:0030707,GO:0030855,GO:0032153,GO:0032154,GO:0032155,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032794,GO:0032879,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0040011,GO:0043062,GO:0043063,GO:0044085,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044459,GO:0044464,GO:0044703,GO:0045171,GO:0045177,GO:0045179,GO:0045216,GO:0045807,GO:0048259,GO:0048260,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048592,GO:0048609,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050839,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051302,GO:0051674,GO:0051704,GO:0051726,GO:0060429,GO:0060627,GO:0065007,GO:0071840,GO:0071944,GO:0090130,GO:0090132,GO:0090596,GO:0097435,GO:0098590,GO:0099568,GO:0099738	2.1.1.43,2.7.11.1	ko:K03068,ko:K06261,ko:K06593,ko:K08867,ko:K09187,ko:K12488,ko:K13738,ko:K14972,ko:K20050,ko:K20371	ko00310,ko04144,ko04150,ko04310,ko04512,ko04520,ko04611,ko04640,ko04666,ko04934,ko05100,ko05200,ko05224,ko05225,ko05226,map00310,map04144,map04150,map04310,map04512,map04520,map04611,map04640,map04666,map04934,map05100,map05200,map05224,map05225,map05226	-	R03875,R03938,R04866,R04867	RC00003,RC00060,RC00181,RC00496	ko00000,ko00001,ko01000,ko01001,ko01009,ko03000,ko03036,ko04090,ko04131,ko04147,ko04516	-	-	-	Ig_3,Ldl_recept_a,SET,SH3_1,SH3_9,V-set
SHD3_k127_523018_16	448385.sce3828	1.95e-35	148.0	COG4700@1|root,COG4700@2|Bacteria	2|Bacteria	T	PFAM Protein kinase domain	-	-	-	ko:K08309	-	-	-	-	ko00000,ko01000,ko01011	-	GH23	-	PLDc_N,TPR_16,TPR_19,TPR_4,TPR_6,TPR_8
SHD3_k127_523018_5	1192034.CAP_3979	2.619e-84	300.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_3979|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_523018_24	983917.RGE_21170	1.067e-05	58.0	COG1652@1|root,COG4254@1|root,COG1652@2|Bacteria,COG4254@2|Bacteria,1NKA2@1224|Proteobacteria,2VMS2@28216|Betaproteobacteria,1KKQB@119065|unclassified Burkholderiales	28216|Betaproteobacteria	S	FecR protein	-	-	-	-	-	-	-	-	-	-	-	-	FecR,LysM
SHD3_k127_523018_0	1192034.CAP_2605	2.567e-215	695.0	COG0421@1|root,COG4262@1|root,COG0421@2|Bacteria,COG4262@2|Bacteria,1QX9D@1224|Proteobacteria,42Q62@68525|delta/epsilon subdivisions,2WMHX@28221|Deltaproteobacteria,2YUT9@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synth
SHD3_k127_523018_9	886293.Sinac_4028	1.238e-56	209.0	COG0702@1|root,COG0702@2|Bacteria	2|Bacteria	GM	epimerase	azoB	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
SHD3_k127_523018_15	448385.sce5956	1.388e-38	153.0	COG1309@1|root,COG1309@2|Bacteria,1RITZ@1224|Proteobacteria,438VB@68525|delta/epsilon subdivisions,2WYC9@28221|Deltaproteobacteria,2Z0YF@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_523018_17	246197.MXAN_2670	7.405e-33	143.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1MYSX@1224|Proteobacteria,43AI4@68525|delta/epsilon subdivisions	1224|Proteobacteria	T	Histidine kinase-like ATPases	asgA	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,Response_reg
SHD3_k127_523018_20	1158146.KB907123_gene544	8.507e-24	115.0	COG4191@1|root,COG4191@2|Bacteria,1MU55@1224|Proteobacteria,1RQ5N@1236|Gammaproteobacteria,1WWAJ@135613|Chromatiales	135613|Chromatiales	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c
SHD3_k127_523018_8	378806.STAUR_3334	1.75e-62	242.0	COG2197@1|root,COG2197@2|Bacteria,1QX8T@1224|Proteobacteria,43C1U@68525|delta/epsilon subdivisions,2X7CF@28221|Deltaproteobacteria,2YZ7U@29|Myxococcales	28221|Deltaproteobacteria	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_523018_12	215803.DB30_6776	8.114e-50	189.0	COG0500@1|root,COG2226@2|Bacteria,1R6F0@1224|Proteobacteria,42QVF@68525|delta/epsilon subdivisions,2WN5H@28221|Deltaproteobacteria,2YWDA@29|Myxococcales	28221|Deltaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
SHD3_k127_523018_2	1297742.A176_06805	2.252e-118	413.0	COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,1RCM9@1224|Proteobacteria,43BK1@68525|delta/epsilon subdivisions,2X6XW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SHD3_k127_523018_10	391625.PPSIR1_07445	2.583e-54	204.0	COG3137@1|root,COG3137@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07283	-	-	-	-	ko00000	-	-	-	DUF481
SHD3_k127_523018_19	118173.KB235914_gene3039	4.279e-26	112.0	COG3428@1|root,COG3428@2|Bacteria,1GE7A@1117|Cyanobacteria	1117|Cyanobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
SHD3_k127_523018_23	1144275.COCOR_07153	7.433e-07	61.0	COG3391@1|root,COG3391@2|Bacteria,1QX9W@1224|Proteobacteria,43C32@68525|delta/epsilon subdivisions,2X7DQ@28221|Deltaproteobacteria,2YVS2@29|Myxococcales	28221|Deltaproteobacteria	S	Stigma-specific protein, Stig1	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_523018_18	448385.sce0848	1.886e-30	139.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce0848|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_523018_7	314278.NB231_14868	2.067e-65	230.0	COG0122@1|root,COG5483@1|root,COG0122@2|Bacteria,COG5483@2|Bacteria,1RDGV@1224|Proteobacteria,1SBHQ@1236|Gammaproteobacteria,1X14P@135613|Chromatiales	135613|Chromatiales	L	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
SHD3_k127_523018_4	504472.Slin_6434	6e-102	351.0	COG2273@1|root,COG2273@2|Bacteria,4NF91@976|Bacteroidetes,47MDE@768503|Cytophagia	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	DUF1735,Glyco_hydro_16,Glyco_hydro_43
SHD3_k127_523018_14	1540221.JQNI01000004_gene233	1.228e-43	178.0	COG0429@1|root,COG3055@1|root,COG0429@2|Bacteria,COG3055@2|Bacteria,1WKZU@1297|Deinococcus-Thermus	2|Bacteria	S	NPCBM	yheT	-	-	ko:K07019	-	-	-	-	ko00000	-	-	-	Abhydrolase_1,NPCBM
SHD3_k127_523018_3	1254432.SCE1572_39610	1.243e-117	395.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,43836@68525|delta/epsilon subdivisions,2X3D4@28221|Deltaproteobacteria,2YVHE@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 30 family	srfJ	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C,RicinB_lectin_2
SHD3_k127_523018_1	469371.Tbis_2599	2.136e-193	630.0	COG1032@1|root,COG1032@2|Bacteria,2HW71@201174|Actinobacteria,4E7P4@85010|Pseudonocardiales	201174|Actinobacteria	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_523018_6	1499967.BAYZ01000108_gene2206	5.724e-81	293.0	COG3829@1|root,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HTH_8,PAS,PAS_4,PAS_9,Response_reg,Sigma54_activat
SHD3_k127_523018_11	876269.ARWA01000001_gene2316	9.655e-51	185.0	COG2020@1|root,COG2020@2|Bacteria,1R7G6@1224|Proteobacteria,2VG1Y@28211|Alphaproteobacteria	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
SHD3_k127_523018_22	1370121.AUWS01000006_gene5264	3.371e-08	58.0	COG2020@1|root,COG2020@2|Bacteria,2I4HM@201174|Actinobacteria,23314@1762|Mycobacteriaceae	201174|Actinobacteria	O	PFAM Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
SHD3_k127_5235457_1	448385.sce8862	1.63e-56	211.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Lipase_GDSL_2,PA14,RicinB_lectin_2,SASA,SLH
SHD3_k127_5235457_0	448385.sce4512	1.901e-86	304.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_5239627_3	1254432.SCE1572_40640	4.737e-143	477.0	COG4206@1|root,COG4206@2|Bacteria,1MW63@1224|Proteobacteria,43C33@68525|delta/epsilon subdivisions,2X7DR@28221|Deltaproteobacteria,2YVIJ@29|Myxococcales	28221|Deltaproteobacteria	P	TonB dependent receptor	-	-	-	ko:K02014,ko:K16092	-	-	-	-	ko00000,ko02000	1.B.14,1.B.14.3	-	-	Plug,TonB_dep_Rec
SHD3_k127_5239627_5	1123508.JH636448_gene7514	7.136e-59	220.0	COG0689@1|root,COG2931@1|root,COG3291@1|root,COG4932@1|root,COG0689@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG4932@2|Bacteria,2J503@203682|Planctomycetes	203682|Planctomycetes	J	Domain of unknown function (DUF4465)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4465,Dockerin_1
SHD3_k127_5239627_8	391625.PPSIR1_14055	3.9e-22	104.0	COG1404@1|root,COG4935@1|root,COG1404@2|Bacteria,COG4935@2|Bacteria,1QZT5@1224|Proteobacteria,42YUM@68525|delta/epsilon subdivisions	1224|Proteobacteria	O	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5239627_7	448385.sce0059	4.01e-29	129.0	COG3628@1|root,COG3628@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5239627_4	1192034.CAP_3979	6.138e-93	326.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_3979|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5239627_6	448385.sce4445	1.892e-39	155.0	COG0355@1|root,COG0355@2|Bacteria,1RHE4@1224|Proteobacteria,42TII@68525|delta/epsilon subdivisions,2WPVK@28221|Deltaproteobacteria,2YW5U@29|Myxococcales	28221|Deltaproteobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
SHD3_k127_5239627_0	1192034.CAP_3411	1.354e-242	757.0	COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,42KZA@68525|delta/epsilon subdivisions,2WJ1V@28221|Deltaproteobacteria,2YU1A@29|Myxococcales	28221|Deltaproteobacteria	F	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
SHD3_k127_5239627_2	1192034.CAP_3409	3.475e-172	565.0	COG0358@1|root,COG0358@2|Bacteria,1MUHC@1224|Proteobacteria,42MDZ@68525|delta/epsilon subdivisions,2WJ9Y@28221|Deltaproteobacteria,2YUT2@29|Myxococcales	28221|Deltaproteobacteria	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
SHD3_k127_5239627_1	1242864.D187_008792	3.976e-209	674.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YUHI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	rpoD	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ner,Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SHD3_k127_5240849_1	1234364.AMSF01000015_gene3298	2.438e-70	249.0	COG3158@1|root,COG3158@2|Bacteria,1MUVH@1224|Proteobacteria,1RPM6@1236|Gammaproteobacteria,1X3P7@135614|Xanthomonadales	135614|Xanthomonadales	P	Transport of potassium into the cell	kup	GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
SHD3_k127_5240849_0	794903.OPIT5_28125	0.0	1208.0	COG3808@1|root,COG3808@2|Bacteria,46S7R@74201|Verrucomicrobia,3K82Q@414999|Opitutae	414999|Opitutae	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
SHD3_k127_5240849_4	1385515.N791_00055	9.727e-10	62.0	COG1826@1|root,COG1826@2|Bacteria,1N6S4@1224|Proteobacteria,1SCC7@1236|Gammaproteobacteria,1X840@135614|Xanthomonadales	135614|Xanthomonadales	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
SHD3_k127_5240849_3	1163409.UUA_01025	4.77e-12	75.0	COG3571@1|root,COG3571@2|Bacteria,1R1FA@1224|Proteobacteria,1T50H@1236|Gammaproteobacteria,1XDAX@135614|Xanthomonadales	135614|Xanthomonadales	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5240849_2	338966.Ppro_0598	7.363e-25	110.0	COG0680@1|root,COG0680@2|Bacteria,1R3V7@1224|Proteobacteria,42RDY@68525|delta/epsilon subdivisions	1224|Proteobacteria	C	hydrogenase maturation protease	hycI	GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.23.51	ko:K08315	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
SHD3_k127_5240849_5	1286171.EAL2_c06880	0.0006089	44.0	COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1UHYA@1239|Firmicutes,24I1D@186801|Clostridia,25X41@186806|Eubacteriaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7,Oxidored_q6
SHD3_k127_5245395_2	391625.PPSIR1_40645	4.497e-60	218.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2WJAX@28221|Deltaproteobacteria,2YTVT@29|Myxococcales	28221|Deltaproteobacteria	C	Fe-S oxidoreductases	-	-	-	ko:K22226	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_5245395_0	1254432.SCE1572_00415	1.529e-129	439.0	COG2885@1|root,COG2885@2|Bacteria,1MWHF@1224|Proteobacteria,43AYZ@68525|delta/epsilon subdivisions,2X6D8@28221|Deltaproteobacteria,2Z2YZ@29|Myxococcales	1224|Proteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03286	-	-	-	-	ko00000,ko02000	1.B.6	-	-	BON,OMP_b-brl,OmpA
SHD3_k127_5245395_1	1192034.CAP_5018	1.153e-92	313.0	COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,42NBY@68525|delta/epsilon subdivisions,2WJV2@28221|Deltaproteobacteria,2YWFP@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ C terminal domain	-	-	-	ko:K03686,ko:K05516	-	-	-	-	ko00000,ko03029,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
SHD3_k127_5247141_5	391625.PPSIR1_29985	2.567e-34	139.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5247141_2	489825.LYNGBM3L_08950	7.951e-61	215.0	COG1305@1|root,COG1305@2|Bacteria,1G3GN@1117|Cyanobacteria,1H7NE@1150|Oscillatoriales	1117|Cyanobacteria	E	PFAM Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Transglut_core
SHD3_k127_5247141_0	279714.FuraDRAFT_1271	9.898e-88	295.0	COG0262@1|root,COG0262@2|Bacteria,1MU1W@1224|Proteobacteria,2VHF9@28216|Betaproteobacteria	28216|Betaproteobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SHD3_k127_5247141_3	1463858.JOHR01000029_gene5766	5.158e-38	161.0	COG0596@1|root,COG0596@2|Bacteria,2GNK7@201174|Actinobacteria	201174|Actinobacteria	S	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
SHD3_k127_5247141_1	1121920.AUAU01000010_gene117	4.873e-75	257.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	MA20_15105	-	-	-	-	-	-	-	-	-	-	-	AHSA1
SHD3_k127_5247141_4	448385.sce2055	2.338e-36	154.0	COG3055@1|root,COG3203@1|root,COG3055@2|Bacteria,COG3203@2|Bacteria,1QA41@1224|Proteobacteria,43DXI@68525|delta/epsilon subdivisions,2X90U@28221|Deltaproteobacteria,2Z1C1@29|Myxococcales	28221|Deltaproteobacteria	M	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5248082_10	469371.Tbis_1693	1.518e-10	70.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4E2ZJ@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
SHD3_k127_5248082_11	980584.AFPB01000089_gene31	2.443e-08	67.0	COG2273@1|root,COG2273@2|Bacteria,4NKCF@976|Bacteroidetes,1I0S5@117743|Flavobacteriia,406SD@61432|unclassified Flavobacteriaceae	976|Bacteroidetes	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_16
SHD3_k127_5248082_7	272560.BPSS0144	2.029e-24	108.0	COG3387@1|root,COG3387@2|Bacteria,1MYVI@1224|Proteobacteria,2VIRI@28216|Betaproteobacteria,1KCU2@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Starch binding domain	-	-	3.2.1.3	ko:K01178	ko00500,ko01100,map00500,map01100	-	R01790,R01791,R06199	-	ko00000,ko00001,ko01000	-	GH15	-	CBM_20,Glucodextran_N,Glyco_hydro_15
SHD3_k127_5248082_0	1122603.ATVI01000005_gene3439	2.65e-227	733.0	COG0286@1|root,COG0286@2|Bacteria,1MWUJ@1224|Proteobacteria,1RRRR@1236|Gammaproteobacteria	1236|Gammaproteobacteria	V	helicase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SHD3_k127_5248082_3	42256.RradSPS_2066	5.213e-64	226.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,4CQ9H@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	pdxH	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
SHD3_k127_5248082_2	1254432.SCE1572_43620	6.279e-77	265.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria	1224|Proteobacteria	KT	Phage shock protein A	pspA	GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SHD3_k127_5248082_6	290397.Adeh_0700	9.285e-38	155.0	COG1377@1|root,COG1377@2|Bacteria,1MUWI@1224|Proteobacteria,42NKR@68525|delta/epsilon subdivisions,2WJIQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	N	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin	yscU	-	-	ko:K02401,ko:K03229	ko02040,ko03070,map02040,map03070	M00332,M00542,M00660	-	-	ko00000,ko00001,ko00002,ko02035,ko02044	3.A.6.1,3.A.6.2,3.A.6.3	-	-	Bac_export_2
SHD3_k127_5248082_1	56780.SYN_01358	8.274e-103	346.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	-	-	1.1.1.3,2.7.6.5,3.1.7.2	ko:K00003,ko:K01139	ko00230,ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R00336,R00429,R01773,R01775	RC00002,RC00078,RC00087	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	HD_4,HTH_3,RelA_SpoT
SHD3_k127_5248082_5	215803.DB30_5287	6.899e-47	188.0	COG2304@1|root,COG2304@2|Bacteria,1MUTS@1224|Proteobacteria,42R8X@68525|delta/epsilon subdivisions,2WN6U@28221|Deltaproteobacteria,2YYGP@29|Myxococcales	28221|Deltaproteobacteria	S	von Willebrand factor type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA
SHD3_k127_5248082_8	880071.Fleli_3602	4.166e-18	98.0	2E9WW@1|root,3342M@2|Bacteria,4P592@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5248082_9	1254432.SCE1572_19380	3.668e-17	84.0	COG3950@1|root,COG3950@2|Bacteria,1MUE0@1224|Proteobacteria	1224|Proteobacteria	L	ATP-binding protein involved in virulence	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
SHD3_k127_5253578_6	396595.TK90_1885	9.978e-40	153.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,1RN2M@1236|Gammaproteobacteria,1WVVQ@135613|Chromatiales	135613|Chromatiales	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
SHD3_k127_5253578_5	1254432.SCE1572_22910	1.915e-58	206.0	COG1327@1|root,COG1327@2|Bacteria,1RE7V@1224|Proteobacteria,42SJP@68525|delta/epsilon subdivisions,2WPK0@28221|Deltaproteobacteria,2YVAV@29|Myxococcales	28221|Deltaproteobacteria	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
SHD3_k127_5253578_0	448385.sce3813	2.766e-177	569.0	COG0304@1|root,COG0304@2|Bacteria,1MU1X@1224|Proteobacteria,42MUZ@68525|delta/epsilon subdivisions,2WJT6@28221|Deltaproteobacteria,2YXTZ@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
SHD3_k127_5253578_7	1254432.SCE1572_22920	1.806e-36	139.0	COG0236@1|root,COG0236@2|Bacteria,1MZ4P@1224|Proteobacteria,42V9M@68525|delta/epsilon subdivisions,2WRDW@28221|Deltaproteobacteria,2YVWU@29|Myxococcales	28221|Deltaproteobacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
SHD3_k127_5253578_4	1254432.SCE1572_22930	1.311e-102	348.0	COG0331@1|root,COG0331@2|Bacteria,1MV6N@1224|Proteobacteria,42MKH@68525|delta/epsilon subdivisions,2WIWQ@28221|Deltaproteobacteria,2YU16@29|Myxococcales	28221|Deltaproteobacteria	I	malonyl CoA-acyl carrier protein transacylase	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
SHD3_k127_5253578_3	1254432.SCE1572_22935	3.139e-132	430.0	COG0332@1|root,COG0332@2|Bacteria,1MU9N@1224|Proteobacteria,42MU6@68525|delta/epsilon subdivisions,2WIJN@28221|Deltaproteobacteria,2YUIT@29|Myxococcales	28221|Deltaproteobacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
SHD3_k127_5253578_9	292459.STH1443	2.87e-15	78.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
SHD3_k127_5253578_8	1254432.SCE1572_22945	4.332e-17	89.0	COG1399@1|root,COG1399@2|Bacteria,1N7GQ@1224|Proteobacteria,42U2P@68525|delta/epsilon subdivisions,2WRMV@28221|Deltaproteobacteria,2YW6X@29|Myxococcales	28221|Deltaproteobacteria	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
SHD3_k127_5253578_1	1254432.SCE1572_22950	1.359e-153	496.0	COG1807@1|root,COG1807@2|Bacteria,1Q2FK@1224|Proteobacteria,4381I@68525|delta/epsilon subdivisions,2X3BM@28221|Deltaproteobacteria,2YUUG@29|Myxococcales	28221|Deltaproteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5253578_2	309801.trd_0582	1.945e-153	491.0	COG1064@1|root,COG1064@2|Bacteria,2G829@200795|Chloroflexi,27YST@189775|Thermomicrobia	189775|Thermomicrobia	S	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N
SHD3_k127_5253578_10	1502724.FF80_02855	2.435e-05	51.0	COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria,3N75W@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	S	Yqey-like protein	MA20_04985	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
SHD3_k127_5256160_0	290397.Adeh_3529	4.691e-122	420.0	COG0642@1|root,COG0784@1|root,COG2461@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,43CCU@68525|delta/epsilon subdivisions,2X7NQ@28221|Deltaproteobacteria,2YX99@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_5256160_3	1121396.KB893057_gene2482	9.932e-47	178.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Big_4,F5_F8_type_C,Laminin_G_3,Metallophos
SHD3_k127_5256160_1	667014.Thein_1524	8.301e-113	379.0	COG0438@1|root,COG0438@2|Bacteria,2GHNP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_5256160_5	1254432.SCE1572_04385	3.053e-31	138.0	COG2885@1|root,COG2885@2|Bacteria,1QAG8@1224|Proteobacteria,4352E@68525|delta/epsilon subdivisions,2WZDB@28221|Deltaproteobacteria,2Z1W3@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SHD3_k127_5256160_7	1254432.SCE1572_34875	8.016e-11	66.0	COG3215@1|root,COG3215@2|Bacteria	2|Bacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ,cNMP_binding
SHD3_k127_5256160_2	521674.Plim_1473	4.94e-97	345.0	COG0515@1|root,COG0515@2|Bacteria,2J50A@203682|Planctomycetes	203682|Planctomycetes	KLT	PFAM Serine threonine protein kinase-related	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,dCache_1
SHD3_k127_5256160_8	290397.Adeh_0078	3.922e-08	61.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5258482_7	1131814.JAFO01000001_gene2365	1.892e-77	269.0	COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,2TRSU@28211|Alphaproteobacteria,3EYWP@335928|Xanthobacteraceae	28211|Alphaproteobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
SHD3_k127_5258482_5	1192034.CAP_0863	5.18e-101	340.0	COG1266@1|root,COG1266@2|Bacteria,1R5BW@1224|Proteobacteria,434JF@68525|delta/epsilon subdivisions,2WYWP@28221|Deltaproteobacteria,2Z0TD@29|Myxococcales	28221|Deltaproteobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
SHD3_k127_5258482_0	251221.35214644	3.213e-253	796.0	COG1166@1|root,COG1166@2|Bacteria,1G1C4@1117|Cyanobacteria	1117|Cyanobacteria	H	Catalyzes the biosynthesis of agmatine from arginine	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
SHD3_k127_5258482_17	1206732.BAGD01000097_gene4249	2.014e-15	86.0	COG2186@1|root,COG2186@2|Bacteria,2I90D@201174|Actinobacteria,4FYCG@85025|Nocardiaceae	201174|Actinobacteria	K	FCD	mce2R	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043207,GO:0043565,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	-	-	-	-	-	-	-	-	-	FCD,GntR
SHD3_k127_5258482_8	1340493.JNIF01000004_gene1038	2.272e-77	278.0	COG0843@1|root,COG0843@2|Bacteria,3Y2X6@57723|Acidobacteria	57723|Acidobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	-	-	-	-	-	-	-	-	-	-	COX1
SHD3_k127_5258482_11	1123242.JH636436_gene296	4.457e-69	246.0	COG1622@1|root,COG2010@1|root,COG1622@2|Bacteria,COG2010@2|Bacteria,2IXB7@203682|Planctomycetes	203682|Planctomycetes	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	-	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM,Cytochrom_C
SHD3_k127_5258482_10	1123242.JH636436_gene293	2.814e-69	251.0	COG4531@1|root,COG4531@2|Bacteria,2IY65@203682|Planctomycetes	203682|Planctomycetes	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5258482_6	502025.Hoch_2415	3.127e-94	324.0	COG2010@1|root,COG2010@2|Bacteria,1RDVX@1224|Proteobacteria,42WYA@68525|delta/epsilon subdivisions,2WT1Y@28221|Deltaproteobacteria,2Z0GX@29|Myxococcales	28221|Deltaproteobacteria	C	Protein of unknown function (DUF3341)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3341
SHD3_k127_5258482_3	521674.Plim_3984	1.005e-152	497.0	COG5557@1|root,COG5557@2|Bacteria,2IWYN@203682|Planctomycetes	203682|Planctomycetes	C	Polysulphide reductase	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
SHD3_k127_5258482_1	1123242.JH636436_gene290	2.249e-232	762.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,2IXNQ@203682|Planctomycetes	203682|Planctomycetes	C	Molybdopterin oxidoreductase, iron-sulfur binding subunit	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7,Molydop_binding
SHD3_k127_5258482_9	502025.Hoch_2412	1.014e-70	246.0	COG3880@1|root,COG3880@2|Bacteria,1RD55@1224|Proteobacteria,42TTE@68525|delta/epsilon subdivisions,2X777@28221|Deltaproteobacteria,2YXUR@29|Myxococcales	28221|Deltaproteobacteria	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_CIII,Cytochrome_C7
SHD3_k127_5258482_2	1254432.SCE1572_42220	2.982e-183	592.0	COG0568@1|root,COG0568@2|Bacteria,1MVNJ@1224|Proteobacteria,42N2S@68525|delta/epsilon subdivisions,2WJ0E@28221|Deltaproteobacteria,2YYKC@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SHD3_k127_5258482_14	1289387.AUKW01000003_gene2427	3.371e-33	147.0	COG4987@1|root,COG4988@1|root,COG4987@2|Bacteria,COG4988@2|Bacteria,2I2DP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD	cydD	-	-	ko:K16013,ko:K16014	ko02010,map02010	-	-	-	ko00000,ko00001,ko02000	3.A.1.129	-	-	ABC_membrane,ABC_tran
SHD3_k127_5258482_4	1192034.CAP_2880	9.252e-137	444.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,42MB0@68525|delta/epsilon subdivisions,2WJ42@28221|Deltaproteobacteria,2YWE0@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	iAF987.Gmet_1415	Phe_tRNA-synt_N,tRNA-synt_2d
SHD3_k127_5258482_13	1192034.CAP_2879	7.633e-39	147.0	COG0292@1|root,COG0292@2|Bacteria,1RGU2@1224|Proteobacteria,42REF@68525|delta/epsilon subdivisions,2WQ4F@28221|Deltaproteobacteria,2YVYH@29|Myxococcales	28221|Deltaproteobacteria	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
SHD3_k127_5258482_16	448385.sce7246	1.621e-17	84.0	COG0291@1|root,COG0291@2|Bacteria,1QDQ4@1224|Proteobacteria,42VSG@68525|delta/epsilon subdivisions,2WREY@28221|Deltaproteobacteria,2Z2C4@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
SHD3_k127_5258482_12	448385.sce8431	1.798e-42	164.0	COG2032@1|root,COG2032@2|Bacteria,1N26J@1224|Proteobacteria,43B8H@68525|delta/epsilon subdivisions,2X6MV@28221|Deltaproteobacteria,2Z3BS@29|Myxococcales	28221|Deltaproteobacteria	P	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	-	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
SHD3_k127_5258482_18	298655.KI912267_gene6841	7.885e-10	71.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_5260598_2	290397.Adeh_4049	3.951e-23	105.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Protein-disulfide isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SHD3_k127_5260598_3	1532558.JL39_16180	4.356e-23	104.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria,4B880@82115|Rhizobiaceae	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_9,Response_reg
SHD3_k127_5260598_4	1265505.ATUG01000002_gene1876	3.726e-20	101.0	COG0509@1|root,COG0509@2|Bacteria,1NRFW@1224|Proteobacteria,42ZAN@68525|delta/epsilon subdivisions,2WUQI@28221|Deltaproteobacteria,2MMY2@213118|Desulfobacterales	28221|Deltaproteobacteria	E	Glycine cleavage H-protein	-	-	-	-	-	-	-	-	-	-	-	-	GCV_H
SHD3_k127_5260598_1	1265505.ATUG01000002_gene1877	6.589e-31	130.0	COG1913@1|root,COG1913@2|Bacteria,1NEU5@1224|Proteobacteria,42WCP@68525|delta/epsilon subdivisions,2X5BA@28221|Deltaproteobacteria,2MN8Z@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase family M54	-	-	-	ko:K06974	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M54
SHD3_k127_5260598_0	945713.IALB_2429	4.951e-156	507.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K02481,ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_5260598_5	1304883.KI912532_gene1775	6.67e-12	66.0	COG2202@1|root,COG2203@1|root,COG3829@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG3829@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2VJGE@28216|Betaproteobacteria,2KV5M@206389|Rhodocyclales	206389|Rhodocyclales	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02482	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	GAF_2,HATPase_c,HisKA,PAS_3,Response_reg
SHD3_k127_5266374_8	1192034.CAP_0165	2.627e-58	212.0	COG1413@1|root,COG1413@2|Bacteria,1PC2V@1224|Proteobacteria,4387S@68525|delta/epsilon subdivisions,2X3HJ@28221|Deltaproteobacteria,2YW4Z@29|Myxococcales	28221|Deltaproteobacteria	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_5266374_5	1192034.CAP_0167	1.327e-98	332.0	2DCII@1|root,2ZE9Y@2|Bacteria,1PA1F@1224|Proteobacteria,433KQ@68525|delta/epsilon subdivisions,2WYI5@28221|Deltaproteobacteria,2YW5W@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5266374_3	448385.sce2908	6.272e-121	400.0	COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,42N3Z@68525|delta/epsilon subdivisions,2WIPM@28221|Deltaproteobacteria,2YY2A@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
SHD3_k127_5266374_11	1254432.SCE1572_17745	4.104e-29	127.0	COG1413@1|root,COG1413@2|Bacteria,1Q31D@1224|Proteobacteria,438RI@68525|delta/epsilon subdivisions,2X3YG@28221|Deltaproteobacteria,2YXKK@29|Myxococcales	28221|Deltaproteobacteria	C	HEAT repeats	cpcE	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_5266374_10	448385.sce2911	4.845e-41	160.0	COG2972@1|root,COG2972@2|Bacteria,1QA94@1224|Proteobacteria,434WZ@68525|delta/epsilon subdivisions,2WZ7X@28221|Deltaproteobacteria,2Z1IT@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5266374_12	1254432.SCE1572_17755	5.474e-28	118.0	COG0792@1|root,COG0792@2|Bacteria,1Q8YJ@1224|Proteobacteria,43AAG@68525|delta/epsilon subdivisions,2X233@28221|Deltaproteobacteria,2Z2KT@29|Myxococcales	28221|Deltaproteobacteria	J	nuclease activity	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
SHD3_k127_5266374_1	1192034.CAP_0175	1.523e-246	772.0	COG0457@1|root,COG0457@2|Bacteria,1P0DI@1224|Proteobacteria,431RN@68525|delta/epsilon subdivisions,2WWCP@28221|Deltaproteobacteria,2Z3IU@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5266374_0	1254432.SCE1572_17770	0.0	1367.0	COG1729@1|root,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria,2YUXH@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SHD3_k127_5266374_4	1254432.SCE1572_17775	2.735e-109	366.0	COG0457@1|root,COG0457@2|Bacteria,1NFC8@1224|Proteobacteria,42VYT@68525|delta/epsilon subdivisions,2WRFT@28221|Deltaproteobacteria,2Z1XW@29|Myxococcales	28221|Deltaproteobacteria	S	adventurous gliding protein T	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_10,TPR_16,TPR_19,TPR_2,TPR_8
SHD3_k127_5267949_1	290397.Adeh_3196	5.179e-10	67.0	COG0262@1|root,COG0262@2|Bacteria,1N2NT@1224|Proteobacteria	1224|Proteobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
SHD3_k127_5267949_0	215803.DB30_6288	1.701e-92	327.0	COG4249@1|root,COG4249@2|Bacteria,1PCBJ@1224|Proteobacteria,438CD@68525|delta/epsilon subdivisions,2X3MP@28221|Deltaproteobacteria,2YWJ1@29|Myxococcales	28221|Deltaproteobacteria	S	Peptidase C14 caspase catalytic subunit p20	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5268269_2	469383.Cwoe_5091	1.248e-42	166.0	COG2706@1|root,COG4409@1|root,COG2706@2|Bacteria,COG4409@2|Bacteria	2|Bacteria	G	exo-alpha-(2->6)-sialidase activity	-	-	-	-	-	-	-	-	-	-	-	-	ASH,BNR_2,Calx-beta,TIG,VCBS
SHD3_k127_5268269_0	448385.sce3398	8.882e-64	232.0	COG4188@1|root,COG4188@2|Bacteria	2|Bacteria	KT	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5268269_4	29850.GGTG_13662T0	1.241e-10	73.0	28JQD@1|root,2QS3Q@2759|Eukaryota,38HXY@33154|Opisthokonta,3NY8Q@4751|Fungi,3QJBJ@4890|Ascomycota,213VW@147550|Sordariomycetes,41Q48@639021|Magnaporthales	4751|Fungi	O	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	AbfB,ArabFuran-catal,CBM_1
SHD3_k127_5268269_5	448385.sce7744	8.877e-08	64.0	COG3266@1|root,COG3266@2|Bacteria,1QA9E@1224|Proteobacteria,434X4@68525|delta/epsilon subdivisions,2WZ81@28221|Deltaproteobacteria,2Z1J2@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5268269_6	391625.PPSIR1_17945	8.068e-05	48.0	COG1595@1|root,COG1595@2|Bacteria,1QA32@1224|Proteobacteria,434TA@68525|delta/epsilon subdivisions,2WZ4A@28221|Deltaproteobacteria,2Z1AN@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5268269_1	641107.CDLVIII_4239	1.528e-46	186.0	COG5520@1|root,COG5520@2|Bacteria,1U8RG@1239|Firmicutes,248NT@186801|Clostridia,36H0Z@31979|Clostridiaceae	186801|Clostridia	G	dockerin type	xynC1	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_2,CBM_4_9,CBM_6,Dockerin_1,Esterase,Glyco_hydro_30,Glyco_hydro_30C,Polysacc_deac_1,RicinB_lectin_2
SHD3_k127_5268269_3	1242864.D187_002450	2.866e-37	156.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,CBM_6,Calx-beta,Cellulase,Collagen_bind_2,DUF4038,RicinB_lectin_2
SHD3_k127_5275079_0	1144275.COCOR_07712	3.095e-114	373.0	COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,437ZU@68525|delta/epsilon subdivisions,2X39R@28221|Deltaproteobacteria,2YV0T@29|Myxococcales	28221|Deltaproteobacteria	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
SHD3_k127_5275079_1	7213.XP_004521881.1	7.903e-05	56.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera	33208|Metazoa	T	Calcium ion binding	dp	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA
SHD3_k127_5284562_4	1254432.SCE1572_50395	8.318e-20	94.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_5284562_2	584708.Apau_0714	2.652e-41	158.0	COG1765@1|root,COG1765@2|Bacteria	2|Bacteria	O	OsmC-like protein	-	-	-	ko:K07397	-	-	-	-	ko00000	-	-	-	DUF3795,OsmC
SHD3_k127_5284562_0	502025.Hoch_1142	4.147e-136	455.0	COG2963@1|root,COG2963@2|Bacteria,1NMA3@1224|Proteobacteria,434KN@68525|delta/epsilon subdivisions,2WYXX@28221|Deltaproteobacteria,2Z0W6@29|Myxococcales	28221|Deltaproteobacteria	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5284562_3	448385.sce0354	4.734e-21	107.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SHD3_k127_5284562_1	153721.MYP_1794	1.193e-57	222.0	COG3291@1|root,COG3405@1|root,COG3291@2|Bacteria,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	2.4.1.12,3.2.1.156,3.2.1.4	ko:K00694,ko:K15531,ko:K20542	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GH8,GT2	-	CHU_C,Glyco_hydro_8,PKD
SHD3_k127_5293030_1	671143.DAMO_2917	6.567e-67	236.0	COG0667@1|root,COG1331@1|root,COG0667@2|Bacteria,COG1331@2|Bacteria,2NP26@2323|unclassified Bacteria	2|Bacteria	O	Protein of unknown function, DUF255	yyaL	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,GlcNAc_2-epim,Thioredox_DsbH
SHD3_k127_5293030_3	448385.sce6967	6.401e-22	101.0	COG2204@1|root,COG2204@2|Bacteria,1NABF@1224|Proteobacteria,43C0I@68525|delta/epsilon subdivisions,2X7B5@28221|Deltaproteobacteria,2Z3KD@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_5293030_2	290315.Clim_1860	3.347e-51	188.0	COG1528@1|root,COG1528@2|Bacteria	2|Bacteria	P	ferric iron binding	ftn	GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771	1.16.3.1,1.16.3.2	ko:K02217,ko:K22336	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
SHD3_k127_5293030_0	1254432.SCE1572_15260	1.764e-107	376.0	COG0564@1|root,COG2265@1|root,COG0564@2|Bacteria,COG2265@2|Bacteria,1MV3A@1224|Proteobacteria,42ME9@68525|delta/epsilon subdivisions,2WKF0@28221|Deltaproteobacteria,2Z219@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
SHD3_k127_5294686_27	1192034.CAP_2649	2.713e-36	144.0	COG2355@1|root,COG2355@2|Bacteria,1MWEW@1224|Proteobacteria,42NXB@68525|delta/epsilon subdivisions,2WMBF@28221|Deltaproteobacteria,2YV6N@29|Myxococcales	28221|Deltaproteobacteria	E	Membrane dipeptidase (Peptidase family M19)	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
SHD3_k127_5294686_10	1192034.CAP_6824	6.577e-87	294.0	COG0568@1|root,COG0568@2|Bacteria,1PBSF@1224|Proteobacteria,433T8@68525|delta/epsilon subdivisions,2X9VU@28221|Deltaproteobacteria,2YVGG@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-70, region 4	asgB	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
SHD3_k127_5294686_17	448385.sce3645	5.422e-52	188.0	COG0789@1|root,COG0789@2|Bacteria,1Q2FZ@1224|Proteobacteria,4382B@68525|delta/epsilon subdivisions,2X3CF@28221|Deltaproteobacteria,2YVED@29|Myxococcales	28221|Deltaproteobacteria	K	MerR HTH family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
SHD3_k127_5294686_11	1254432.SCE1572_22015	3.217e-83	288.0	COG2267@1|root,COG2267@2|Bacteria,1P3EB@1224|Proteobacteria,43EDS@68525|delta/epsilon subdivisions,2X82V@28221|Deltaproteobacteria,2Z2G4@29|Myxococcales	28221|Deltaproteobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SHD3_k127_5294686_4	1254432.SCE1572_22030	6.278e-146	488.0	COG0515@1|root,COG0745@1|root,COG3266@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG3266@2|Bacteria,1NVZF@1224|Proteobacteria,42ZUK@68525|delta/epsilon subdivisions,2X7NR@28221|Deltaproteobacteria,2Z3H7@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,Response_reg
SHD3_k127_5294686_8	1254432.SCE1572_22030	3.079e-95	330.0	COG0515@1|root,COG0745@1|root,COG3266@1|root,COG0515@2|Bacteria,COG0745@2|Bacteria,COG3266@2|Bacteria,1NVZF@1224|Proteobacteria,42ZUK@68525|delta/epsilon subdivisions,2X7NR@28221|Deltaproteobacteria,2Z3H7@29|Myxococcales	28221|Deltaproteobacteria	T	Domain of unknown function (DUF4388)	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF4388,Response_reg
SHD3_k127_5294686_13	1192034.CAP_6831	1.793e-78	282.0	COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,2YUUH@29|Myxococcales	28221|Deltaproteobacteria	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,DUF4339,DZR,SHOCT,zinc_ribbon_2
SHD3_k127_5294686_6	1192034.CAP_6832	1.47e-106	361.0	2DMMW@1|root,32SIJ@2|Bacteria,1N004@1224|Proteobacteria,42TSJ@68525|delta/epsilon subdivisions,2WQHG@28221|Deltaproteobacteria,2YV84@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5294686_24	1121918.ARWE01000001_gene434	1.192e-39	151.0	COG0864@1|root,COG0864@2|Bacteria,1RK4R@1224|Proteobacteria,42SID@68525|delta/epsilon subdivisions,2WQ86@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	transcriptional regulator	nikR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K07722	-	-	-	-	ko00000,ko03000	-	-	-	NikR_C,RHH_1
SHD3_k127_5294686_3	1192034.CAP_2972	1.682e-161	535.0	COG0826@1|root,COG0826@2|Bacteria,1MUQG@1224|Proteobacteria,42M8P@68525|delta/epsilon subdivisions,2WMKS@28221|Deltaproteobacteria,2YWJ3@29|Myxococcales	28221|Deltaproteobacteria	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
SHD3_k127_5294686_29	1041142.ATTP01000019_gene5223	7.667e-18	87.0	COG4691@1|root,COG4691@2|Bacteria,1N7UI@1224|Proteobacteria,2UFQB@28211|Alphaproteobacteria,4BH33@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	plasmid stabilization protein	-	-	-	ko:K21495	-	-	-	-	ko00000,ko02048	-	-	-	-
SHD3_k127_5294686_18	1336235.JAEG01000023_gene1076	1.906e-45	168.0	COG1487@1|root,COG1487@2|Bacteria,1MZQC@1224|Proteobacteria,2U73E@28211|Alphaproteobacteria,4BFHT@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	PIN domain	vapC	-	-	ko:K07062	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PIN
SHD3_k127_5294686_22	1254432.SCE1572_22055	1.674e-41	163.0	COG3147@1|root,COG3147@2|Bacteria,1NGE3@1224|Proteobacteria,43C1W@68525|delta/epsilon subdivisions,2X7CG@28221|Deltaproteobacteria,2YVUH@29|Myxococcales	28221|Deltaproteobacteria	S	Sporulation related domain	-	-	-	-	-	-	-	-	-	-	-	-	SPOR
SHD3_k127_5294686_2	1192034.CAP_6865	2.541e-201	651.0	COG0018@1|root,COG0018@2|Bacteria,1MU4J@1224|Proteobacteria,42MTY@68525|delta/epsilon subdivisions,2WKII@28221|Deltaproteobacteria,2YWMT@29|Myxococcales	28221|Deltaproteobacteria	J	Arginyl tRNA synthetase N terminal dom	argS	GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	iAF987.Gmet_1434	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
SHD3_k127_5294686_12	1192034.CAP_7081	1.771e-82	291.0	COG0147@1|root,COG0147@2|Bacteria,1MVBJ@1224|Proteobacteria,42P55@68525|delta/epsilon subdivisions,2WJNC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	EH	PFAM chorismate	pabB	-	2.6.1.85	ko:K01665	ko00790,map00790	-	R01716	RC00010,RC01418	ko00000,ko00001,ko01000	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
SHD3_k127_5294686_30	298655.KI912267_gene7618	2.803e-06	60.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_5294686_14	1254432.SCE1572_22395	1.069e-71	252.0	COG1208@1|root,COG1208@2|Bacteria,1R9ZD@1224|Proteobacteria,42SI2@68525|delta/epsilon subdivisions,2WQPV@28221|Deltaproteobacteria,2YVRY@29|Myxococcales	28221|Deltaproteobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
SHD3_k127_5294686_21	448385.sce4449	7.765e-43	175.0	COG0705@1|root,COG0705@2|Bacteria	2|Bacteria	S	proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
SHD3_k127_5294686_16	448385.sce3821	2.812e-64	224.0	COG2065@1|root,COG2065@2|Bacteria,1RI6U@1224|Proteobacteria,42S2E@68525|delta/epsilon subdivisions,2WMT9@28221|Deltaproteobacteria,2YVDA@29|Myxococcales	28221|Deltaproteobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
SHD3_k127_5294686_5	1192034.CAP_6139	1.304e-124	412.0	COG0540@1|root,COG0540@2|Bacteria,1MWAB@1224|Proteobacteria,42NMR@68525|delta/epsilon subdivisions,2WJQR@28221|Deltaproteobacteria,2YU78@29|Myxococcales	28221|Deltaproteobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
SHD3_k127_5294686_9	448385.sce4844	8.241e-94	316.0	COG0796@1|root,COG0796@2|Bacteria,1NAI2@1224|Proteobacteria,42P58@68525|delta/epsilon subdivisions,2WKYK@28221|Deltaproteobacteria,2YY1K@29|Myxococcales	28221|Deltaproteobacteria	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0547	Asp_Glu_race
SHD3_k127_5294686_1	640081.Dsui_3372	1.711e-203	657.0	28HUW@1|root,2Z81F@2|Bacteria,1Q3QA@1224|Proteobacteria,2VK1A@28216|Betaproteobacteria,2KVYD@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5294686_0	1254432.SCE1572_30410	0.0	1328.0	COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,42M9W@68525|delta/epsilon subdivisions,2WJ29@28221|Deltaproteobacteria,2YUPG@29|Myxococcales	28221|Deltaproteobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SHD3_k127_5294686_7	1192034.CAP_5548	4.161e-101	338.0	COG0223@1|root,COG0223@2|Bacteria,1MU4Q@1224|Proteobacteria,42M3E@68525|delta/epsilon subdivisions,2WKMK@28221|Deltaproteobacteria,2YUSE@29|Myxococcales	28221|Deltaproteobacteria	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
SHD3_k127_5294686_20	502025.Hoch_6055	3.451e-43	169.0	2AGE4@1|root,316JY@2|Bacteria,1PXQC@1224|Proteobacteria,434RK@68525|delta/epsilon subdivisions,2WZ2R@28221|Deltaproteobacteria,2Z17A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5294686_19	448385.sce1810	1.325e-44	168.0	COG1413@1|root,COG1413@2|Bacteria,1RK8P@1224|Proteobacteria,42VXW@68525|delta/epsilon subdivisions,2WRH4@28221|Deltaproteobacteria,2Z1BY@29|Myxococcales	28221|Deltaproteobacteria	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_5308510_7	1254432.SCE1572_10160	7.372e-14	71.0	COG1352@1|root,COG1352@2|Bacteria,1MU6W@1224|Proteobacteria,42QPJ@68525|delta/epsilon subdivisions,2WMNM@28221|Deltaproteobacteria,2YUW4@29|Myxococcales	28221|Deltaproteobacteria	H	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP	cheR40H-1	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
SHD3_k127_5308510_5	1192034.CAP_0922	1.634e-123	407.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42M27@68525|delta/epsilon subdivisions,2X5MZ@28221|Deltaproteobacteria,2Z36F@29|Myxococcales	28221|Deltaproteobacteria	J	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SHD3_k127_5308510_4	502025.Hoch_4790	1.331e-129	430.0	COG0265@1|root,COG0265@2|Bacteria,1MU63@1224|Proteobacteria,42NB6@68525|delta/epsilon subdivisions,2WIWE@28221|Deltaproteobacteria,2YYCB@29|Myxococcales	28221|Deltaproteobacteria	M	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
SHD3_k127_5308510_1	35754.JNYJ01000023_gene8263	1.532e-225	714.0	COG3509@1|root,COG5434@1|root,COG3509@2|Bacteria,COG5434@2|Bacteria,2IDY2@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl hydrolases family 28	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_28
SHD3_k127_5308510_2	1254432.SCE1572_11400	2.953e-144	472.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria	1224|Proteobacteria	Q	Esterase, phb depolymerase family	phaZ1	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SHD3_k127_5308510_3	1121272.KB903290_gene4833	3.604e-144	472.0	COG3509@1|root,COG5297@1|root,COG3509@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria,4D8FN@85008|Micromonosporales	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	3.2.1.55	ko:K20844	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	CBM42,GH54	-	ArabFuran-catal,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_5308510_6	1254432.SCE1572_50990	4.297e-40	163.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin_3,CelD_N,Glyco_hydro_11,Glyco_hydro_9,HemolysinCabind,Lipase_GDSL_2,Polysacc_deac_1,SASA
SHD3_k127_5308510_0	1254432.SCE1572_03510	0.0	1155.0	COG1501@1|root,COG1501@2|Bacteria,1MWNJ@1224|Proteobacteria,430UT@68525|delta/epsilon subdivisions,2X6PU@28221|Deltaproteobacteria,2Z3C4@29|Myxococcales	28221|Deltaproteobacteria	G	Domain of unknown function (DUF5110)	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
SHD3_k127_5308510_8	28042.GU90_14950	1.73e-10	66.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4E2KG@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5327662_20	1144275.COCOR_01585	6.405e-06	56.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
SHD3_k127_5327662_9	1192034.CAP_4718	9.224e-61	224.0	COG3108@1|root,COG3108@2|Bacteria	2|Bacteria	S	Peptidase M15	-	-	-	ko:K02395	-	-	-	-	ko00000,ko02035	-	-	-	Glucosaminidase,Peptidase_M15_2,Peptidase_M15_3,PhageMin_Tail
SHD3_k127_5327662_6	448385.sce1791	2.872e-78	283.0	COG2812@1|root,COG2812@2|Bacteria,1QVB3@1224|Proteobacteria,42SBC@68525|delta/epsilon subdivisions,2WPCK@28221|Deltaproteobacteria,2YVD8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
SHD3_k127_5327662_12	448385.sce1789	4.802e-56	203.0	COG0352@1|root,COG0352@2|Bacteria,1RDSU@1224|Proteobacteria,42R5Z@68525|delta/epsilon subdivisions,2WMPN@28221|Deltaproteobacteria,2YVXC@29|Myxococcales	28221|Deltaproteobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
SHD3_k127_5327662_14	378806.STAUR_2130	2.956e-44	177.0	COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1MWJA@1224|Proteobacteria,42P8D@68525|delta/epsilon subdivisions,2WMH1@28221|Deltaproteobacteria,2YY1Q@29|Myxococcales	28221|Deltaproteobacteria	KLT	Phosphotransferase enzyme family	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase,Pkinase_Tyr,WD40
SHD3_k127_5327662_11	448385.sce1774	3.534e-57	216.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce1774|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5327662_18	768679.TTX_0160	5.198e-09	66.0	COG0727@1|root,arCOG02579@2157|Archaea	2157|Archaea	S	Fe-S-cluster oxidoreductase	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
SHD3_k127_5327662_5	1192034.CAP_2042	6.35e-82	286.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2X7DF@28221|Deltaproteobacteria,2YY2W@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_5327662_2	1192034.CAP_7997	5.574e-126	419.0	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX5U@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
SHD3_k127_5327662_1	1192034.CAP_7998	4.437e-141	461.0	COG2268@1|root,COG2268@2|Bacteria,1QIR4@1224|Proteobacteria,42Q0N@68525|delta/epsilon subdivisions,2WJDJ@28221|Deltaproteobacteria,2YX63@29|Myxococcales	28221|Deltaproteobacteria	S	prohibitin homologues	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
SHD3_k127_5327662_16	1192034.CAP_7999	7.388e-34	139.0	2AS5D@1|root,32BXX@2|Bacteria,1QADV@1224|Proteobacteria,4350N@68525|delta/epsilon subdivisions,2X93Y@28221|Deltaproteobacteria,2Z1S2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5327662_19	326424.FRAAL4481	3.067e-07	63.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,4ESDB@85013|Frankiales	201174|Actinobacteria	L	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
SHD3_k127_5327662_3	518766.Rmar_0806	1.268e-121	398.0	COG0113@1|root,COG0113@2|Bacteria,4NFW6@976|Bacteroidetes,1FJ2J@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Delta-aminolevulinic acid dehydratase	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
SHD3_k127_5327662_13	443143.GM18_0083	8.353e-51	194.0	COG2234@1|root,COG2234@2|Bacteria,1MXZS@1224|Proteobacteria,42S82@68525|delta/epsilon subdivisions,2WNUR@28221|Deltaproteobacteria,43TZW@69541|Desulfuromonadales	28221|Deltaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
SHD3_k127_5327662_10	1382356.JQMP01000003_gene2161	1.94e-60	215.0	COG0041@1|root,COG0041@2|Bacteria,2G6JS@200795|Chloroflexi,27YJ0@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
SHD3_k127_5327662_4	1192034.CAP_6426	1.66e-100	336.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YZAP@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
SHD3_k127_5327662_0	641491.DND132_1157	1.301e-168	542.0	COG0372@1|root,COG0372@2|Bacteria,1MUKX@1224|Proteobacteria,42N8U@68525|delta/epsilon subdivisions,2WJAN@28221|Deltaproteobacteria,2M8J0@213115|Desulfovibrionales	28221|Deltaproteobacteria	C	Belongs to the citrate synthase family	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
SHD3_k127_5327662_8	1047013.AQSP01000140_gene2512	2.772e-64	237.0	COG1226@1|root,COG1226@2|Bacteria,2NP71@2323|unclassified Bacteria	2|Bacteria	U	Ion channel	kch	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans_2,TrkA_C,TrkA_N
SHD3_k127_5327662_7	477974.Daud_0459	4.759e-75	262.0	COG1090@1|root,COG1090@2|Bacteria,1TRCE@1239|Firmicutes,24GWH@186801|Clostridia,261G8@186807|Peptococcaceae	186801|Clostridia	S	PFAM NAD dependent epimerase dehydratase family	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
SHD3_k127_5337037_0	1068978.AMETH_3649	2.028e-225	712.0	COG0492@1|root,COG0492@2|Bacteria,2GK62@201174|Actinobacteria,4E11F@85010|Pseudonocardiales	201174|Actinobacteria	KOT	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
SHD3_k127_5337037_2	926560.KE387027_gene603	1.632e-31	132.0	COG0406@1|root,COG0406@2|Bacteria	2|Bacteria	G	alpha-ribazole phosphatase activity	-	-	3.1.3.85,5.4.2.11,5.4.2.12	ko:K01834,ko:K15634,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
SHD3_k127_5337037_4	45351.EDO30841	4.278e-18	96.0	2BVT1@1|root,2SBPC@2759|Eukaryota	2759|Eukaryota	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5337037_1	1192034.CAP_8540	3.683e-49	181.0	COG1595@1|root,COG1595@2|Bacteria,1N38X@1224|Proteobacteria,42U8K@68525|delta/epsilon subdivisions,2WQZR@28221|Deltaproteobacteria,2YY8N@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5346127_8	868131.MSWAN_0998	1.909e-31	124.0	COG2873@1|root,arCOG00061@2157|Archaea,2XSWM@28890|Euryarchaeota,23NN2@183925|Methanobacteria	183925|Methanobacteria	E	sulfhydrylase	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
SHD3_k127_5346127_3	404589.Anae109_0929	6.242e-71	246.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1RE8Z@1224|Proteobacteria,42VZV@68525|delta/epsilon subdivisions,2WRHV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SHD3_k127_5346127_6	1192034.CAP_1738	1.472e-51	205.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1RE8Z@1224|Proteobacteria,42VZV@68525|delta/epsilon subdivisions,2WRHV@28221|Deltaproteobacteria,2YVUE@29|Myxococcales	28221|Deltaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
SHD3_k127_5346127_5	246197.MXAN_6173	1.375e-52	208.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
SHD3_k127_5346127_1	1000565.METUNv1_03586	1.149e-107	358.0	COG0625@1|root,COG0625@2|Bacteria,1MUN3@1224|Proteobacteria,2VHCD@28216|Betaproteobacteria,2KW9G@206389|Rhodocyclales	206389|Rhodocyclales	O	Belongs to the GST superfamily	-	-	-	ko:K11209	-	-	-	-	ko00000,ko01000	-	-	-	GST_C,GST_N
SHD3_k127_5346127_9	747365.Thena_1663	4.721e-05	55.0	COG0859@1|root,COG0859@2|Bacteria,1UYYX@1239|Firmicutes,24ETA@186801|Clostridia	2|Bacteria	M	PFAM Glycosyltransferase family 9 (heptosyltransferase)	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
SHD3_k127_5346127_4	1122963.AUHB01000016_gene4350	3.631e-59	226.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2U3I4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_5346127_0	1122963.AUHB01000016_gene4350	1.256e-109	369.0	COG0641@1|root,COG0641@2|Bacteria,1MX3M@1224|Proteobacteria,2U3I4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_5346127_2	1122963.AUHB01000016_gene4348	2.847e-80	278.0	COG0535@1|root,COG0535@2|Bacteria	2|Bacteria	I	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_5347523_5	509191.AEDB02000002_gene1141	7.439e-62	215.0	COG3507@1|root,COG4193@1|root,COG4733@1|root,COG3507@2|Bacteria,COG4193@2|Bacteria,COG4733@2|Bacteria,1UYQE@1239|Firmicutes,24C16@186801|Clostridia,3WI7H@541000|Ruminococcaceae	186801|Clostridia	G	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,Laminin_G_3
SHD3_k127_5347523_1	1303518.CCALI_01285	2.4e-113	402.0	COG1874@1|root,COG1874@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35,Glyco_hydro_42C
SHD3_k127_5347523_0	1408473.JHXO01000005_gene1551	3.056e-171	555.0	COG3507@1|root,COG3507@2|Bacteria,4PKXQ@976|Bacteroidetes,2FNWV@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 43 family	xynD_2	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Glyco_hydro_43
SHD3_k127_5347523_3	219305.MCAG_03934	1.433e-82	289.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4D9F4@85008|Micromonosporales	201174|Actinobacteria	Q	Ricin-type beta-trefoil	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_5347523_2	448385.sce3992	1.586e-94	322.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_5347523_4	3218.PP1S55_131V6.1	9.373e-77	275.0	COG3669@1|root,KOG3340@2759|Eukaryota,37NEY@33090|Viridiplantae,3GGSX@35493|Streptophyta	35493|Streptophyta	G	Alpha-l-fucosidase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004560,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0006516,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009100,GO:0009987,GO:0015928,GO:0016787,GO:0016798,GO:0019538,GO:0030163,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
SHD3_k127_5350445_1	479434.Sthe_0979	8.001e-148	489.0	COG0128@1|root,COG0128@2|Bacteria,2G6S6@200795|Chloroflexi,27Y0N@189775|Thermomicrobia	189775|Thermomicrobia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
SHD3_k127_5350445_4	391625.PPSIR1_21744	4.619e-30	132.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	-	-	-	-	-	-	-	-	-	-	CAP
SHD3_k127_5350445_2	378806.STAUR_6512	3.229e-97	345.0	COG3119@1|root,COG3119@2|Bacteria,1MV0B@1224|Proteobacteria,43AH9@68525|delta/epsilon subdivisions,2X5XB@28221|Deltaproteobacteria,2Z37F@29|Myxococcales	28221|Deltaproteobacteria	P	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SHD3_k127_5350445_5	1120972.AUMH01000023_gene544	4.059e-25	123.0	COG3119@1|root,COG3119@2|Bacteria,1VAJC@1239|Firmicutes,4HGBS@91061|Bacilli	91061|Bacilli	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SHD3_k127_5350445_0	314285.KT71_18426	9.559e-165	533.0	28I8B@1|root,2Z8B5@2|Bacteria,1MUNM@1224|Proteobacteria,1RQ1H@1236|Gammaproteobacteria,1J4H2@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c bacterial	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Cytochrome_cB
SHD3_k127_5354581_2	1254432.SCE1572_22905	3.996e-88	296.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1MUWT@1224|Proteobacteria,42NBS@68525|delta/epsilon subdivisions,2WIP2@28221|Deltaproteobacteria,2YUVJ@29|Myxococcales	28221|Deltaproteobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1624	RibD_C,dCMP_cyt_deam_1
SHD3_k127_5354581_4	1192034.CAP_6151	3.747e-58	206.0	COG0242@1|root,COG0242@2|Bacteria,1RA2P@1224|Proteobacteria,42RFN@68525|delta/epsilon subdivisions,2WP25@28221|Deltaproteobacteria,2YVE0@29|Myxococcales	28221|Deltaproteobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
SHD3_k127_5354581_1	1254432.SCE1572_22895	3.813e-120	411.0	COG1716@1|root,COG4962@1|root,COG1716@2|Bacteria,COG4962@2|Bacteria,1R7EN@1224|Proteobacteria,42NAK@68525|delta/epsilon subdivisions,2WIYX@28221|Deltaproteobacteria,2YTSI@29|Myxococcales	28221|Deltaproteobacteria	TU	Type II IV secretion system protein	-	-	-	ko:K02283,ko:K03609	-	-	-	-	ko00000,ko02035,ko02044,ko03036,ko04812	-	-	-	CbiA,FHA,T2SSE
SHD3_k127_5354581_0	1254432.SCE1572_23140	3.926e-132	437.0	COG0457@1|root,COG0789@1|root,COG0457@2|Bacteria,COG0789@2|Bacteria,1PQD2@1224|Proteobacteria,4323R@68525|delta/epsilon subdivisions,2WXJB@28221|Deltaproteobacteria,2Z10C@29|Myxococcales	28221|Deltaproteobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TPR_1,TPR_17,TPR_8
SHD3_k127_5354581_3	1254432.SCE1572_27205	2.595e-86	297.0	COG0388@1|root,COG0388@2|Bacteria,1MUUB@1224|Proteobacteria,42T24@68525|delta/epsilon subdivisions,2WPF8@28221|Deltaproteobacteria,2YV09@29|Myxococcales	28221|Deltaproteobacteria	S	PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	ko:K11206	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
SHD3_k127_5354581_7	448385.sce5096	1.362e-05	51.0	COG1716@1|root,COG3829@1|root,COG1716@2|Bacteria,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria,43BKG@68525|delta/epsilon subdivisions,2X1VT@28221|Deltaproteobacteria,2YWWI@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma-54 dependent transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_28,Sigma54_activat
SHD3_k127_5359101_1	1121022.ABENE_12130	1.262e-115	401.0	COG1680@1|root,COG3291@1|root,COG1680@2|Bacteria,COG3291@2|Bacteria,1QWZ9@1224|Proteobacteria,2TYW9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CelD_N,Glyco_hydro_9
SHD3_k127_5359101_4	1095769.CAHF01000023_gene465	4.689e-53	197.0	COG2382@1|root,COG2382@2|Bacteria,1QWH3@1224|Proteobacteria,2WGZS@28216|Betaproteobacteria	28216|Betaproteobacteria	P	esterase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5359101_3	1056816.JAFQ01000004_gene6300	2.649e-57	216.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4FX82@85025|Nocardiaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
SHD3_k127_5359101_0	435591.BDI_1057	1.546e-127	416.0	COG1052@1|root,COG1052@2|Bacteria,4NF1R@976|Bacteroidetes,2FMNY@200643|Bacteroidia,22WSN@171551|Porphyromonadaceae	976|Bacteroidetes	CH	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
SHD3_k127_5359101_5	448385.sce6967	1.247e-27	117.0	COG2204@1|root,COG2204@2|Bacteria,1NABF@1224|Proteobacteria,43C0I@68525|delta/epsilon subdivisions,2X7B5@28221|Deltaproteobacteria,2Z3KD@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_5359101_2	1121413.JMKT01000014_gene2447	3.968e-69	244.0	COG2230@1|root,COG2230@2|Bacteria,1R1J6@1224|Proteobacteria,43DEG@68525|delta/epsilon subdivisions,2X8KD@28221|Deltaproteobacteria,2MHIT@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
SHD3_k127_5359101_6	331113.SNE_A01070	5.542e-21	104.0	COG2849@1|root,COG2849@2|Bacteria,2JGQS@204428|Chlamydiae	204428|Chlamydiae	S	MORN repeat variant	-	-	-	-	-	-	-	-	-	-	-	-	MORN_2
SHD3_k127_5359101_7	338963.Pcar_2376	1.637e-15	85.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria,43RY1@69541|Desulfuromonadales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5359101_8	1232437.KL661988_gene230	2.569e-12	69.0	2C2F5@1|root,32WND@2|Bacteria,1ND6R@1224|Proteobacteria,42Q4T@68525|delta/epsilon subdivisions,2WK9F@28221|Deltaproteobacteria,2MHXS@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5361011_4	28564.XP_002340131.1	1.25e-81	280.0	KOG4155@1|root,KOG4155@2759|Eukaryota,3AG0Y@33154|Opisthokonta,3Q4RG@4751|Fungi,3RN16@4890|Ascomycota,20UKC@147545|Eurotiomycetes,3SE9V@5042|Eurotiales	4751|Fungi	S	Encoded by	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,NACHT,WD40
SHD3_k127_5361011_7	179408.Osc7112_1469	8.598e-12	71.0	COG2337@1|root,COG2337@2|Bacteria,1G7FJ@1117|Cyanobacteria,1HCDG@1150|Oscillatoriales	1117|Cyanobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
SHD3_k127_5361011_1	1448860.BBJO01000041_gene1989	1.145e-94	328.0	COG1061@1|root,arCOG00874@2157|Archaea,2XTYQ@28890|Euryarchaeota,23SWE@183963|Halobacteria	183963|Halobacteria	K	COG1061 DNA or RNA helicases of superfamily II	rad25	-	-	-	-	-	-	-	-	-	-	-	ERCC3_RAD25_C,ResIII
SHD3_k127_5361011_6	926554.KI912633_gene3644	2.978e-14	85.0	COG3372@1|root,COG3372@2|Bacteria	2|Bacteria	S	COGs COG3372 conserved	-	-	-	ko:K09744	-	-	-	-	ko00000	-	-	-	DUF790
SHD3_k127_5361011_5	1125863.JAFN01000001_gene3141	5.894e-24	109.0	COG0586@1|root,COG1409@1|root,COG0586@2|Bacteria,COG1409@2|Bacteria,1R6V4@1224|Proteobacteria,42XP4@68525|delta/epsilon subdivisions,2WT5P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
SHD3_k127_5361011_3	1254432.SCE1572_38140	1.125e-89	315.0	COG1995@1|root,COG1995@2|Bacteria,1MX5W@1224|Proteobacteria,42NJJ@68525|delta/epsilon subdivisions,2WJGI@28221|Deltaproteobacteria,2YV17@29|Myxococcales	28221|Deltaproteobacteria	C	Belongs to the PdxA family	pdxA	-	1.1.1.262,1.1.1.408,1.1.1.409	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
SHD3_k127_5361011_2	448385.sce6445	4.951e-92	313.0	COG0745@1|root,COG0745@2|Bacteria,1QA39@1224|Proteobacteria,43DXD@68525|delta/epsilon subdivisions,2WZ4F@28221|Deltaproteobacteria,2Z1B4@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
SHD3_k127_5361011_0	1254432.SCE1572_38155	2.863e-114	381.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
SHD3_k127_5367009_1	1121448.DGI_1657	1.232e-70	243.0	COG3871@1|root,COG3871@2|Bacteria,1NWAM@1224|Proteobacteria,42ZZ2@68525|delta/epsilon subdivisions,2WV91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Pyrid_ox_like
SHD3_k127_5367009_3	1254432.SCE1572_34115	3.423e-63	230.0	COG0823@1|root,COG0823@2|Bacteria,1RI0N@1224|Proteobacteria	1224|Proteobacteria	U	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14,VPEP
SHD3_k127_5367009_7	369723.Strop_0635	7.544e-42	169.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4D930@85008|Micromonosporales	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
SHD3_k127_5367009_2	436229.JOEH01000008_gene4097	2.335e-70	253.0	COG4124@1|root,COG4124@2|Bacteria,2GMW5@201174|Actinobacteria,2NMCQ@228398|Streptacidiphilus	201174|Actinobacteria	G	Glycosyl hydrolase family 26	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_26
SHD3_k127_5367009_6	1254432.SCE1572_48805	1.479e-44	175.0	COG2273@1|root,COG2273@2|Bacteria,1R709@1224|Proteobacteria	1224|Proteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	CBM_10,CBM_5_12_2,Glyco_hydro_16
SHD3_k127_5367009_5	1209072.ALBT01000017_gene4193	5.143e-50	191.0	COG2273@1|root,COG2730@1|root,COG2273@2|Bacteria,COG2730@2|Bacteria,1RANY@1224|Proteobacteria,1S8N5@1236|Gammaproteobacteria,1FH24@10|Cellvibrio	1236|Gammaproteobacteria	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
SHD3_k127_5367009_0	518766.Rmar_2616	1.115e-155	517.0	COG1472@1|root,COG1472@2|Bacteria,4NE90@976|Bacteroidetes,1FIS9@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_5367009_4	573061.Clocel_3242	4.22e-62	231.0	COG2730@1|root,COG5297@1|root,COG2730@2|Bacteria,COG5297@2|Bacteria,1UYCF@1239|Firmicutes,24989@186801|Clostridia,36FED@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	GO:0000272,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005975,GO:0005976,GO:0006073,GO:0006080,GO:0008150,GO:0008152,GO:0008810,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010391,GO:0010410,GO:0016052,GO:0016787,GO:0016788,GO:0016798,GO:0017144,GO:0030243,GO:0030245,GO:0030246,GO:0030247,GO:0030248,GO:0042737,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0045491,GO:0045493,GO:0046555,GO:0051273,GO:0051275,GO:0052689,GO:0071554,GO:0071704,GO:1901575,GO:2000884	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Cellulase,Dockerin_1,Lipase_GDSL_2
SHD3_k127_5367009_8	1382359.JIAL01000001_gene78	0.0005623	44.0	COG1917@1|root,COG2169@1|root,COG1917@2|Bacteria,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.2.2.21	ko:K02099,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,AraC_binding,Cupin_2,Endonuclea_NS_2,HTH_18,HTH_AraC
SHD3_k127_5376182_10	215803.DB30_7610	2.221e-17	97.0	COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales	28221|Deltaproteobacteria	MU	PKD domain	-	-	-	-	-	-	-	-	-	-	-	-	PKD
SHD3_k127_5376182_2	378806.STAUR_5697	1.163e-151	494.0	COG0766@1|root,COG0766@2|Bacteria,1MUH7@1224|Proteobacteria,42MJT@68525|delta/epsilon subdivisions,2WJ7W@28221|Deltaproteobacteria,2YUNU@29|Myxococcales	28221|Deltaproteobacteria	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
SHD3_k127_5376182_9	1192034.CAP_2391	2.476e-20	100.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
SHD3_k127_5376182_7	448385.sce9146	3.846e-42	161.0	COG2885@1|root,COG2885@2|Bacteria,1MX1F@1224|Proteobacteria,42UTB@68525|delta/epsilon subdivisions,2WQUW@28221|Deltaproteobacteria,2YUE1@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	Big_3_2,DUF11,OmpA,Phenol_MetA_deg,TSP_3
SHD3_k127_5376182_4	1192034.CAP_7616	9.138e-83	301.0	COG1413@1|root,COG1413@2|Bacteria	2|Bacteria	C	deoxyhypusine monooxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_5376182_8	903818.KI912268_gene3161	2.876e-37	160.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	peb4	-	5.2.1.8	ko:K01802,ko:K03769	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,Rotamase_3,SurA_N_3
SHD3_k127_5376182_0	485918.Cpin_4545	7.832e-165	538.0	COG3533@1|root,COG3533@2|Bacteria,4P23R@976|Bacteroidetes	976|Bacteroidetes	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5376182_11	1192034.CAP_7617	1.074e-15	80.0	COG1722@1|root,COG1722@2|Bacteria,1Q1MN@1224|Proteobacteria,437C8@68525|delta/epsilon subdivisions,2X2HR@28221|Deltaproteobacteria,2YW46@29|Myxococcales	28221|Deltaproteobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
SHD3_k127_5376182_5	1254432.SCE1572_38425	4.255e-72	255.0	COG1058@1|root,COG1058@2|Bacteria,1MVG6@1224|Proteobacteria,42R50@68525|delta/epsilon subdivisions,2X3AE@28221|Deltaproteobacteria,2YV4E@29|Myxococcales	28221|Deltaproteobacteria	S	nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
SHD3_k127_5376182_6	448385.sce6487	1.94e-58	212.0	COG2003@1|root,COG2003@2|Bacteria,1MXZ5@1224|Proteobacteria,42PPW@68525|delta/epsilon subdivisions,2WM1S@28221|Deltaproteobacteria,2YVFT@29|Myxococcales	28221|Deltaproteobacteria	L	Belongs to the UPF0758 family	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
SHD3_k127_5376182_3	1254432.SCE1572_38305	8.857e-145	475.0	COG0631@1|root,COG0664@1|root,COG0631@2|Bacteria,COG0664@2|Bacteria,1R7UF@1224|Proteobacteria,42WUQ@68525|delta/epsilon subdivisions,2XA41@28221|Deltaproteobacteria,2YTYP@29|Myxococcales	28221|Deltaproteobacteria	T	SMART protein phosphatase 2C domain protein	pp2c12	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2,cNMP_binding
SHD3_k127_5376182_1	1254432.SCE1572_38300	2.772e-162	528.0	2AIWW@1|root,319EI@2|Bacteria,1Q2HU@1224|Proteobacteria,4384N@68525|delta/epsilon subdivisions,2X3EQ@28221|Deltaproteobacteria,2YVQU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5383178_0	448385.sce5944	0.0	1342.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,1MX82@1224|Proteobacteria,42TQ9@68525|delta/epsilon subdivisions,2WR3B@28221|Deltaproteobacteria,2YUCZ@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
SHD3_k127_5383178_2	1254432.SCE1572_35380	2.873e-122	410.0	COG0457@1|root,COG0457@2|Bacteria,1PDTX@1224|Proteobacteria,42RK5@68525|delta/epsilon subdivisions,2WNZC@28221|Deltaproteobacteria,2YW1B@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	SPOR,TPR_1,TPR_11,TPR_16,TPR_19,TPR_2,TPR_8
SHD3_k127_5383178_1	1254432.SCE1572_35365	2.239e-151	491.0	COG0810@1|root,COG0810@2|Bacteria,1R65W@1224|Proteobacteria,42XJ0@68525|delta/epsilon subdivisions,2WT3A@28221|Deltaproteobacteria,2YYW2@29|Myxococcales	28221|Deltaproteobacteria	M	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins	-	-	-	-	-	-	-	-	-	-	-	-	TonB_C
SHD3_k127_5383178_6	1254432.SCE1572_35360	3.105e-38	151.0	2A45D@1|root,30SQF@2|Bacteria,1PC1Y@1224|Proteobacteria,43879@68525|delta/epsilon subdivisions,2X3H7@28221|Deltaproteobacteria,2YW2Q@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5383178_3	448385.sce5938	2.84e-119	399.0	2BR4Z@1|root,32K2Z@2|Bacteria,1Q2KX@1224|Proteobacteria,4387K@68525|delta/epsilon subdivisions,2XA10@28221|Deltaproteobacteria,2YW3X@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5383178_4	1254432.SCE1572_35350	4.841e-63	224.0	COG1596@1|root,COG1596@2|Bacteria,1N7GP@1224|Proteobacteria,42MNP@68525|delta/epsilon subdivisions,2WMJZ@28221|Deltaproteobacteria,2YVBP@29|Myxococcales	28221|Deltaproteobacteria	M	polysaccharide export	wza2	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
SHD3_k127_5383178_5	1192034.CAP_0029	6.938e-42	168.0	COG2885@1|root,COG2885@2|Bacteria,1NRFN@1224|Proteobacteria,43CZ4@68525|delta/epsilon subdivisions,2X87C@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SHD3_k127_5405202_5	1254432.SCE1572_13870	8.297e-46	181.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5405202_3	1192034.CAP_3878	1.151e-90	310.0	2ANCN@1|root,31DB7@2|Bacteria,1QAGG@1224|Proteobacteria,4352J@68525|delta/epsilon subdivisions,2WZDK@28221|Deltaproteobacteria,2Z1WK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5405202_10	290397.Adeh_3735	5.286e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,1PEZT@1224|Proteobacteria,42W2J@68525|delta/epsilon subdivisions,2WS5K@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5405202_2	251221.35210928	8.184e-111	367.0	COG0580@1|root,COG0580@2|Bacteria,1G0AW@1117|Cyanobacteria	1117|Cyanobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	iJN678.apqZ	MIP
SHD3_k127_5405202_1	448385.sce6491	1.766e-223	709.0	COG1964@1|root,COG1964@2|Bacteria,1QE02@1224|Proteobacteria,42M4B@68525|delta/epsilon subdivisions,2WJDI@28221|Deltaproteobacteria,2YZG3@29|Myxococcales	28221|Deltaproteobacteria	S	4Fe-4S single cluster domain	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SHD3_k127_5405202_4	1192034.CAP_7142	9.569e-48	189.0	COG2908@1|root,COG2908@2|Bacteria	2|Bacteria	M	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	3.6.1.54	ko:K03269	ko00540,ko01100,map00540,map01100	M00060	R04549	RC00002	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Metallophos,Metallophos_2
SHD3_k127_5405202_7	391625.PPSIR1_28911	4.231e-18	92.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_5405202_6	391625.PPSIR1_28916	9.666e-46	179.0	COG0845@1|root,COG0845@2|Bacteria,1MXGH@1224|Proteobacteria,42RCZ@68525|delta/epsilon subdivisions,2WN2W@28221|Deltaproteobacteria,2YWQC@29|Myxococcales	28221|Deltaproteobacteria	M	Biotin-lipoyl like	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_D23
SHD3_k127_5405202_0	391625.PPSIR1_28921	6.578e-312	989.0	COG0841@1|root,COG0841@2|Bacteria,1MU48@1224|Proteobacteria,42MF6@68525|delta/epsilon subdivisions,2WJ8D@28221|Deltaproteobacteria,2YXGU@29|Myxococcales	28221|Deltaproteobacteria	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
SHD3_k127_5418033_5	665571.STHERM_c02090	7.341e-08	54.0	COG1136@1|root,COG1136@2|Bacteria,2J7FN@203691|Spirochaetes	203691|Spirochaetes	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003,ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_5418033_1	518766.Rmar_2535	1.746e-50	198.0	COG4591@1|root,COG4591@2|Bacteria,4NHBR@976|Bacteroidetes	976|Bacteroidetes	M	ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SHD3_k127_5418033_2	1121405.dsmv_2058	7.308e-45	179.0	COG4591@1|root,COG4591@2|Bacteria,1R4Q2@1224|Proteobacteria,42N3Y@68525|delta/epsilon subdivisions,2WJFS@28221|Deltaproteobacteria,2MJEA@213118|Desulfobacterales	28221|Deltaproteobacteria	M	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
SHD3_k127_5418033_0	335543.Sfum_2496	1.196e-54	205.0	COG2834@1|root,COG2834@2|Bacteria,1R5U8@1224|Proteobacteria,42MIS@68525|delta/epsilon subdivisions,2WMK7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
SHD3_k127_5418033_3	483219.LILAB_24970	3.491e-23	108.0	COG1309@1|root,COG1309@2|Bacteria,1N2GG@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_5418033_4	502025.Hoch_6345	3.348e-21	102.0	COG1309@1|root,COG1309@2|Bacteria,1NDYG@1224|Proteobacteria,42WJ9@68525|delta/epsilon subdivisions,2X293@28221|Deltaproteobacteria,2YZAR@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
SHD3_k127_5418033_6	1297742.A176_06348	0.0006931	51.0	2EIZM@1|root,33CQT@2|Bacteria,1P1YR@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5436198_2	1192034.CAP_0774	1.523e-23	103.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_0774|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5436198_3	1254432.SCE1572_35060	9.145e-20	96.0	COG2979@1|root,COG2979@2|Bacteria	2|Bacteria	T	Protein of unknown function (DUF533)	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	LETM1,TerB
SHD3_k127_5436198_1	1254432.SCE1572_28550	1.138e-39	153.0	COG0545@1|root,COG0545@2|Bacteria	2|Bacteria	O	Peptidyl-prolyl cis-trans isomerase	-	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C
SHD3_k127_5436198_0	1191523.MROS_1573	4.961e-137	456.0	COG0077@1|root,COG1605@1|root,COG2876@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,COG2876@2|Bacteria	2|Bacteria	E	3-deoxy-7-phosphoheptulonate synthase activity	pheA	GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	1.3.1.12,2.3.1.79,2.5.1.54,4.2.1.51,5.4.99.5	ko:K00661,ko:K03856,ko:K04092,ko:K04093,ko:K04516,ko:K04518,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00022,M00024,M00025	R00691,R01373,R01715,R01728,R01826	RC00125,RC00360,RC00435,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	iECNA114_1301.ECNA114_2667	ACT,CM_2,PDT
SHD3_k127_5436198_4	1192034.CAP_0384	2.269e-18	89.0	COG1716@1|root,COG1716@2|Bacteria,1PFN8@1224|Proteobacteria,435DQ@68525|delta/epsilon subdivisions,2WZR8@28221|Deltaproteobacteria,2Z2JZ@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SHD3_k127_5458890_0	552811.Dehly_0385	3.024e-172	546.0	COG2873@1|root,COG2873@2|Bacteria,2G5NS@200795|Chloroflexi	200795|Chloroflexi	E	PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	CoA_binding_2,Cys_Met_Meta_PP
SHD3_k127_5458890_1	56780.SYN_01253	2.626e-150	481.0	COG0031@1|root,COG0031@2|Bacteria,1MUBE@1224|Proteobacteria,42N1R@68525|delta/epsilon subdivisions,2WJ7R@28221|Deltaproteobacteria,2MQT2@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	cysteine synthase A	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SHD3_k127_5458890_3	1254432.SCE1572_11740	8.005e-09	67.0	COG1705@1|root,COG3409@1|root,COG1705@2|Bacteria,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.5.1.28	ko:K01448,ko:K02395,ko:K17733	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036	-	-	-	Amidase_3,Glucosaminidase,PG_binding_1,Rod-binding
SHD3_k127_5458890_2	391625.PPSIR1_07842	4.6e-69	251.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2WKZ1@28221|Deltaproteobacteria,2YZ6I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_546566_2	290397.Adeh_2841	2.683e-96	321.0	COG0501@1|root,COG0501@2|Bacteria,1MUV4@1224|Proteobacteria,42MEE@68525|delta/epsilon subdivisions,2WJYV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
SHD3_k127_546566_4	414684.RC1_2368	5.045e-23	110.0	COG2930@1|root,COG2930@2|Bacteria,1RHV6@1224|Proteobacteria,2U9N6@28211|Alphaproteobacteria,2JSQS@204441|Rhodospirillales	204441|Rhodospirillales	S	Las17-binding protein actin regulator	-	-	-	-	-	-	-	-	-	-	-	-	Ysc84
SHD3_k127_546566_1	404589.Anae109_1597	3.484e-115	422.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42M0Y@68525|delta/epsilon subdivisions,2X7MY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase A domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SHD3_k127_546566_0	443143.GM18_4017	0.0	1889.0	COG0515@1|root,COG2203@1|root,COG3899@1|root,COG0515@2|Bacteria,COG2203@2|Bacteria,COG3899@2|Bacteria,1RGKE@1224|Proteobacteria,43DX3@68525|delta/epsilon subdivisions,2X71G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GAF_2,HATPase_c,HisKA_3,Pkinase,STAS
SHD3_k127_546566_3	1297742.A176_01023	1.463e-25	113.0	COG3591@1|root,COG3591@2|Bacteria,1NP6U@1224|Proteobacteria,42ZKY@68525|delta/epsilon subdivisions,2WUS6@28221|Deltaproteobacteria,2YUM8@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the peptidase S1B family	-	-	-	-	-	-	-	-	-	-	-	-	Trypsin_2
SHD3_k127_5466015_4	1254432.SCE1572_38155	1.384e-71	261.0	COG0457@1|root,COG3170@1|root,COG0457@2|Bacteria,COG3170@2|Bacteria,1R7RK@1224|Proteobacteria,42PPY@68525|delta/epsilon subdivisions,2WKX6@28221|Deltaproteobacteria,2YUCP@29|Myxococcales	28221|Deltaproteobacteria	NU	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19
SHD3_k127_5466015_0	521674.Plim_2671	1.126e-307	970.0	COG0189@1|root,COG0769@1|root,COG0189@2|Bacteria,COG0769@2|Bacteria,2IXGZ@203682|Planctomycetes	203682|Planctomycetes	M	cyanophycin synthetase	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M,RimK
SHD3_k127_5466015_1	1123242.JH636435_gene2214	2.393e-255	815.0	COG1181@1|root,COG1181@2|Bacteria,2J54E@203682|Planctomycetes	203682|Planctomycetes	M	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase_M
SHD3_k127_5466015_2	521674.Plim_4037	1.073e-244	788.0	COG1132@1|root,COG1132@2|Bacteria,2IX22@203682|Planctomycetes	203682|Planctomycetes	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
SHD3_k127_5466015_3	497965.Cyan7822_5350	8.018e-202	636.0	COG0500@1|root,COG0500@2|Bacteria,1GHCT@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_13,Methyltransf_14,Methyltransf_23
SHD3_k127_5473283_2	929712.KI912613_gene1225	1.864e-30	125.0	COG1848@1|root,COG1848@2|Bacteria,2GUVQ@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5473283_3	935848.JAEN01000029_gene2815	9.759e-20	100.0	COG2931@1|root,COG2931@2|Bacteria,1PH02@1224|Proteobacteria,2V8WH@28211|Alphaproteobacteria,2PY2T@265|Paracoccus	28211|Alphaproteobacteria	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
SHD3_k127_5473283_4	1144275.COCOR_03158	3.123e-11	74.0	COG3055@1|root,COG3055@2|Bacteria,1MYQG@1224|Proteobacteria,42P3T@68525|delta/epsilon subdivisions,2WKUC@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Galactose oxidase, central domain	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,PKD
SHD3_k127_5473283_1	1144275.COCOR_04219	2.966e-68	250.0	COG5184@1|root,COG5184@2|Bacteria	2|Bacteria	DZ	guanyl-nucleotide exchange factor activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,RCC1,RCC1_2
SHD3_k127_5473283_0	1242864.D187_001183	1.067e-98	337.0	COG2730@1|root,COG2730@2|Bacteria,1MV2T@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	egl	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	Cellulase
SHD3_k127_5484599_1	208444.JNYY01000009_gene3429	0.0006809	48.0	COG3325@1|root,COG5297@1|root,COG3325@2|Bacteria,COG5297@2|Bacteria,2HDPZ@201174|Actinobacteria,4E329@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolase family 12	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,Glyco_hydro_12,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_5484599_0	477641.MODMU_0396	1.976e-23	112.0	COG3786@1|root,COG5479@1|root,COG3786@2|Bacteria,COG5479@2|Bacteria,2GNX8@201174|Actinobacteria,4ETA4@85013|Frankiales	201174|Actinobacteria	D	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
SHD3_k127_5484706_0	448385.sce7089	3.265e-75	267.0	COG3693@1|root,COG3693@2|Bacteria,1R7BZ@1224|Proteobacteria	1224|Proteobacteria	G	Beta-xylanase	-	-	-	-	-	-	-	-	-	-	-	-	CBM60,CBM_10,CBM_2,CBM_4_9,CBM_5_12_2,CBM_6,Glyco_hydro_10,Glyco_hydro_43,SASA
SHD3_k127_5484706_2	313612.L8106_22119	1.733e-14	78.0	COG3668@1|root,COG3668@2|Bacteria,1G8WD@1117|Cyanobacteria,1HDM2@1150|Oscillatoriales	1117|Cyanobacteria	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
SHD3_k127_5493223_2	1254432.SCE1572_27345	9.766e-15	79.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,42V1U@68525|delta/epsilon subdivisions,2WR76@28221|Deltaproteobacteria,2Z26G@29|Myxococcales	28221|Deltaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
SHD3_k127_5493223_0	1254432.SCE1572_27340	8.818e-227	722.0	COG0342@1|root,COG0342@2|Bacteria,1MV5U@1224|Proteobacteria,42M6V@68525|delta/epsilon subdivisions,2WJCI@28221|Deltaproteobacteria,2YU0A@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SHD3_k127_5493223_1	1242864.D187_004564	4.018e-60	223.0	COG0341@1|root,COG0341@2|Bacteria,1MU74@1224|Proteobacteria,42M2H@68525|delta/epsilon subdivisions,2WJ8I@28221|Deltaproteobacteria,2YUZD@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	-	-	ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
SHD3_k127_5501319_7	378806.STAUR_7977	4.057e-39	148.0	COG4637@1|root,COG4637@2|Bacteria,1PFJA@1224|Proteobacteria,4325S@68525|delta/epsilon subdivisions,2WX6S@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5501319_0	867903.ThesuDRAFT_02368	2.365e-275	880.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3WCCU@538999|Clostridiales incertae sedis	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SHD3_k127_5501319_1	448385.sce7888	1.416e-211	670.0	COG0750@1|root,COG0750@2|Bacteria,1MU91@1224|Proteobacteria,42NJ0@68525|delta/epsilon subdivisions,2WJ7A@28221|Deltaproteobacteria,2YTYT@29|Myxococcales	28221|Deltaproteobacteria	M	Peptidase family M50	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
SHD3_k127_5501319_5	290397.Adeh_3970	3.729e-59	222.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1MWPE@1224|Proteobacteria,42P2T@68525|delta/epsilon subdivisions,2WJ9B@28221|Deltaproteobacteria,2YV48@29|Myxococcales	28221|Deltaproteobacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	rsmB	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
SHD3_k127_5501319_2	448385.sce8027	4.157e-99	333.0	COG0329@1|root,COG0329@2|Bacteria,1MUCM@1224|Proteobacteria,42M0X@68525|delta/epsilon subdivisions,2WK4D@28221|Deltaproteobacteria,2YUVE@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
SHD3_k127_5501319_4	1192034.CAP_4874	7.657e-80	288.0	COG0289@1|root,COG0289@2|Bacteria,1MUCT@1224|Proteobacteria,42N84@68525|delta/epsilon subdivisions,2WJKT@28221|Deltaproteobacteria,2YZXG@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
SHD3_k127_5501319_6	926549.KI421517_gene1757	4.21e-43	174.0	COG0682@1|root,COG0682@2|Bacteria,4NFP7@976|Bacteroidetes,47KQC@768503|Cytophagia	976|Bacteroidetes	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
SHD3_k127_5501319_3	502025.Hoch_6744	5.786e-96	319.0	COG1573@1|root,COG1573@2|Bacteria,1PIX8@1224|Proteobacteria,42P41@68525|delta/epsilon subdivisions,2WM40@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	PFAM Uracil-DNA glycosylase superfamily	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
SHD3_k127_5501319_8	290397.Adeh_1143	1.304e-05	49.0	COG1012@1|root,COG1012@2|Bacteria,1R528@1224|Proteobacteria,433YD@68525|delta/epsilon subdivisions,2X42A@28221|Deltaproteobacteria,2YY1Y@29|Myxococcales	28221|Deltaproteobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.5	ko:K00129	ko00010,ko00340,ko00350,ko00360,ko00410,ko00980,ko00982,ko01100,ko01110,ko01120,ko05204,map00010,map00340,map00350,map00360,map00410,map00980,map00982,map01100,map01110,map01120,map05204	-	R00711,R00904,R02536,R02537,R02695,R02697,R03300,R03302,R04882,R04883,R04888,R04889,R04891,R04892,R04996,R07104,R08282,R08283,R08307	RC00047,RC00080,RC00242,RC01735	ko00000,ko00001,ko01000	-	-	-	Aldedh
SHD3_k127_5513817_0	1122927.KB895423_gene3757	1.179e-127	439.0	COG3420@1|root,COG4099@1|root,COG5492@1|root,COG3420@2|Bacteria,COG4099@2|Bacteria,COG5492@2|Bacteria,1VR20@1239|Firmicutes,4HVGA@91061|Bacilli,26V79@186822|Paenibacillaceae	91061|Bacilli	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2
SHD3_k127_5513817_1	1303518.CCALI_01844	2.406e-63	230.0	COG5309@1|root,COG5309@2|Bacteria	2|Bacteria	G	chondroitin AC lyase activity	-	-	-	ko:K21000	ko02025,map02025	-	-	-	ko00000,ko00001	-	GH39	-	CBM_6,Glyco_hydro_cc
SHD3_k127_5528911_1	1384054.N790_02125	7.618e-13	75.0	2ECEX@1|root,336D4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5528911_0	1220534.B655_1034	7.469e-64	242.0	COG1032@1|root,arCOG01356@2157|Archaea	2157|Archaea	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_5548255_1	502025.Hoch_6848	4.481e-56	215.0	2A7CW@1|root,30W9W@2|Bacteria,1QAR7@1224|Proteobacteria,43591@68525|delta/epsilon subdivisions,2WZK7@28221|Deltaproteobacteria,2Z2AT@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5548255_0	1192034.CAP_5588	2.889e-60	225.0	COG1807@1|root,COG1807@2|Bacteria,1N5QJ@1224|Proteobacteria	1224|Proteobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_5548384_9	448385.sce3839	4.698e-67	237.0	COG2849@1|root,COG2849@2|Bacteria,1RJWA@1224|Proteobacteria,42VHV@68525|delta/epsilon subdivisions,2WRR0@28221|Deltaproteobacteria,2YVQD@29|Myxococcales	28221|Deltaproteobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5548384_5	1254432.SCE1572_23035	1.503e-86	293.0	COG1187@1|root,COG1187@2|Bacteria,1MUCE@1224|Proteobacteria,42NI7@68525|delta/epsilon subdivisions,2WNPX@28221|Deltaproteobacteria,2YUXM@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the pseudouridine synthase RsuA family	rluB	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
SHD3_k127_5548384_6	1192034.CAP_8242	7.629e-76	287.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	AXE1,Peptidase_S9
SHD3_k127_5548384_12	448385.sce3938	1.079e-30	126.0	2E6J8@1|root,3316B@2|Bacteria,1N7GY@1224|Proteobacteria,42V6W@68525|delta/epsilon subdivisions,2WRHG@28221|Deltaproteobacteria,2YYZA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5548384_13	1254432.SCE1572_23630	2.898e-27	118.0	2CIY5@1|root,2ZET1@2|Bacteria,1P8MM@1224|Proteobacteria,4330I@68525|delta/epsilon subdivisions,2WXKY@28221|Deltaproteobacteria,2YW19@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5548384_2	1192034.CAP_7037	6.299e-144	468.0	COG0006@1|root,COG0006@2|Bacteria,1MUZS@1224|Proteobacteria,42M1K@68525|delta/epsilon subdivisions,2WJRH@28221|Deltaproteobacteria,2YUPB@29|Myxococcales	28221|Deltaproteobacteria	E	Aminopeptidase P, N-terminal domain	pepP	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
SHD3_k127_5548384_7	1254432.SCE1572_14525	1.392e-71	253.0	COG0682@1|root,COG0682@2|Bacteria,1Q2R4@1224|Proteobacteria,438CQ@68525|delta/epsilon subdivisions,2WP0G@28221|Deltaproteobacteria,2YWK4@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SHD3_k127_5548384_10	502025.Hoch_2148	1.064e-59	218.0	COG1597@1|root,COG1597@2|Bacteria,1RCJT@1224|Proteobacteria,42W6W@68525|delta/epsilon subdivisions,2X6V3@28221|Deltaproteobacteria,2YUYD@29|Myxococcales	28221|Deltaproteobacteria	I	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
SHD3_k127_5548384_8	448385.sce2406	2.162e-67	239.0	COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria	1224|Proteobacteria	S	PFAM RNP-1 like RNA-binding protein	rbpA	-	-	-	-	-	-	-	-	-	-	-	RRM_1
SHD3_k127_5548384_1	1192034.CAP_7535	3.404e-205	640.0	COG1077@1|root,COG1077@2|Bacteria,1MUMW@1224|Proteobacteria,42M1J@68525|delta/epsilon subdivisions,2WIQR@28221|Deltaproteobacteria,2YTUE@29|Myxococcales	28221|Deltaproteobacteria	D	Rod shape-determining protein	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
SHD3_k127_5548384_4	1192034.CAP_7534	1.989e-99	332.0	COG1792@1|root,COG1792@2|Bacteria,1N8ZS@1224|Proteobacteria,42S9I@68525|delta/epsilon subdivisions,2WNTW@28221|Deltaproteobacteria,2YVI1@29|Myxococcales	28221|Deltaproteobacteria	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
SHD3_k127_5548384_0	448385.sce2411	1.819e-232	736.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2YU5Y@29|Myxococcales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	iAF987.Gmet_0928	PBP_dimer,Transpeptidase
SHD3_k127_5548384_3	448385.sce2412	3.584e-126	417.0	COG0772@1|root,COG0772@2|Bacteria,1MUK3@1224|Proteobacteria,42MQT@68525|delta/epsilon subdivisions,2WIP1@28221|Deltaproteobacteria,2YUT8@29|Myxococcales	28221|Deltaproteobacteria	D	Belongs to the SEDS family	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
SHD3_k127_5551160_5	903818.KI912268_gene1635	1.771e-28	123.0	COG1053@1|root,COG1053@2|Bacteria	2|Bacteria	C	succinate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,Succ_DH_flav_C
SHD3_k127_5551160_7	177437.HRM2_01150	1.935e-11	68.0	COG1146@1|root,COG1146@2|Bacteria,1NCND@1224|Proteobacteria,43BSD@68525|delta/epsilon subdivisions,2WY6D@28221|Deltaproteobacteria	1224|Proteobacteria	C	4Fe-4S ferredoxin, iron-sulfur binding family protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
SHD3_k127_5551160_2	926569.ANT_09020	6.35e-113	378.0	COG0477@1|root,COG2814@2|Bacteria,2G8W5@200795|Chloroflexi	200795|Chloroflexi	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
SHD3_k127_5551160_1	452637.Oter_0327	3.618e-118	404.0	COG3507@1|root,COG3507@2|Bacteria,46TKI@74201|Verrucomicrobia,3KA3C@414999|Opitutae	2|Bacteria	G	PFAM glycoside hydrolase family 62	-	-	1.16.3.3	ko:K22350	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,Big_4,CBM_4_9,CBM_6,DUF1080,DUF1349,DUF5011,Flg_new,GSDH,Glyco_hydro_43,Laminin_G_3,PKD,RicinB_lectin_2,SLH,ThuA
SHD3_k127_5551160_0	383372.Rcas_0264	1.951e-160	527.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5551160_4	383372.Rcas_0264	2.184e-31	127.0	COG5184@1|root,COG5184@2|Bacteria,2G8WU@200795|Chloroflexi,3765G@32061|Chloroflexia	32061|Chloroflexia	DZ	PFAM regulator of chromosome condensation, RCC1	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5551160_9	1192034.CAP_3097	3.832e-10	69.0	COG0653@1|root,COG0653@2|Bacteria,1MUJZ@1224|Proteobacteria,42MMV@68525|delta/epsilon subdivisions,2WIZ4@28221|Deltaproteobacteria,2YU97@29|Myxococcales	28221|Deltaproteobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
SHD3_k127_5551160_8	246197.MXAN_0367	3.637e-11	69.0	29QYF@1|root,30BZA@2|Bacteria,1QTGV@1224|Proteobacteria,43E38@68525|delta/epsilon subdivisions,2WZJY@28221|Deltaproteobacteria,2Z2AA@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5551160_11	1121373.KB903664_gene2635	9.171e-06	58.0	COG1397@1|root,COG1397@2|Bacteria,4P1DN@976|Bacteroidetes,47T8F@768503|Cytophagia	976|Bacteroidetes	O	ADP-ribosylglycohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5551160_6	448385.sce1944	2.64e-21	106.0	2EKQJ@1|root,33EEC@2|Bacteria,1Q6FB@1224|Proteobacteria,4331H@68525|delta/epsilon subdivisions,2WXFD@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5551160_3	357808.RoseRS_1799	1.722e-64	238.0	COG2006@1|root,COG2006@2|Bacteria,2G86X@200795|Chloroflexi	200795|Chloroflexi	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_5551160_10	797114.C475_00767	1.023e-08	66.0	arCOG03858@1|root,arCOG03858@2157|Archaea,2XX40@28890|Euryarchaeota,23VUT@183963|Halobacteria	183963|Halobacteria	G	Glycosyl hydrolase family 12	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_12
SHD3_k127_5556798_0	1192034.CAP_2703	5.602e-156	509.0	COG0793@1|root,COG0793@2|Bacteria,1MU39@1224|Proteobacteria,42MHD@68525|delta/epsilon subdivisions,2WTUX@28221|Deltaproteobacteria,2YTTM@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the peptidase S41A family	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
SHD3_k127_5556798_3	404589.Anae109_2333	1.391e-70	246.0	COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,42NZY@68525|delta/epsilon subdivisions,2WJDY@28221|Deltaproteobacteria,2YVHT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1885	PdxJ
SHD3_k127_5556798_5	1254432.SCE1572_02530	1.391e-31	138.0	COG0736@1|root,COG0736@2|Bacteria,1MZBF@1224|Proteobacteria,42TWY@68525|delta/epsilon subdivisions,2WRSQ@28221|Deltaproteobacteria,2Z1VF@29|Myxococcales	28221|Deltaproteobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
SHD3_k127_5556798_1	1254432.SCE1572_02535	5.384e-148	487.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1MU1Q@1224|Proteobacteria,42ND6@68525|delta/epsilon subdivisions,2WIJS@28221|Deltaproteobacteria,2YURF@29|Myxococcales	28221|Deltaproteobacteria	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
SHD3_k127_5556798_4	1254432.SCE1572_02555	2.349e-47	176.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_5556798_2	143224.JQMD01000002_gene1706	2.065e-98	345.0	COG4030@1|root,COG4030@2|Bacteria,4NIPI@976|Bacteroidetes,1I3X3@117743|Flavobacteriia	976|Bacteroidetes	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
SHD3_k127_5559315_4	1122921.KB898189_gene682	3.447e-85	320.0	COG0265@1|root,COG3291@1|root,COG0265@2|Bacteria,COG3291@2|Bacteria,1UNWN@1239|Firmicutes	1239|Firmicutes	O	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SHD3_k127_5559315_16	246197.MXAN_0886	2.5e-06	62.0	COG0402@1|root,COG2374@1|root,COG0402@2|Bacteria,COG2374@2|Bacteria,1NFUA@1224|Proteobacteria,433MB@68525|delta/epsilon subdivisions,2WXJF@28221|Deltaproteobacteria,2YUGP@29|Myxococcales	28221|Deltaproteobacteria	F	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,DUF4215,LTD,TSP_3
SHD3_k127_5559315_3	1449050.JNLE01000003_gene2230	1.183e-85	321.0	COG3291@1|root,COG3420@1|root,COG3291@2|Bacteria,COG3420@2|Bacteria,1UY76@1239|Firmicutes,25G76@186801|Clostridia,36PFI@31979|Clostridiaceae	186801|Clostridia	P	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SHD3_k127_5559315_13	946362.XP_004996892.1	1.379e-14	89.0	28N08@1|root,2QUJ0@2759|Eukaryota	2759|Eukaryota	-	-	MUC4	GO:0001894,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003008,GO:0003674,GO:0005102,GO:0005176,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007586,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010669,GO:0012505,GO:0016020,GO:0016021,GO:0016266,GO:0019538,GO:0022600,GO:0023052,GO:0030197,GO:0030277,GO:0031012,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031974,GO:0032501,GO:0034645,GO:0036211,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0048871,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0071704,GO:0071944,GO:0080134,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K22017	-	-	-	-	ko00000,ko04131	-	-	-	NIDO,VWD
SHD3_k127_5559315_20	1392498.JQLH01000001_gene3251	0.0002618	55.0	COG4447@1|root,COG4447@2|Bacteria,4NEZQ@976|Bacteroidetes,1HWS9@117743|Flavobacteriia,2PI3H@252356|Maribacter	976|Bacteroidetes	S	Thrombospondin type 3 repeat	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Laminin_G_3,PKD,Sortilin-Vps10,TSP_3
SHD3_k127_5559315_0	1123242.JH636436_gene121	6.458e-184	599.0	COG4122@1|root,COG4122@2|Bacteria,2IXSM@203682|Planctomycetes	203682|Planctomycetes	S	O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5559315_1	404589.Anae109_2802	4.73e-122	421.0	COG5184@1|root,COG5184@2|Bacteria,1R504@1224|Proteobacteria,42QHC@68525|delta/epsilon subdivisions,2WKUI@28221|Deltaproteobacteria,2YU2V@29|Myxococcales	28221|Deltaproteobacteria	DZ	Alpha-tubulin suppressor and related RCC1 domain-containing	-	-	-	-	-	-	-	-	-	-	-	-	RCC1,RCC1_2
SHD3_k127_5559315_14	1278073.MYSTI_05967	1.961e-13	84.0	2AIZJ@1|root,319HM@2|Bacteria,1Q2SU@1224|Proteobacteria,438EK@68525|delta/epsilon subdivisions,2X3PJ@28221|Deltaproteobacteria,2YWS6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Stig1
SHD3_k127_5559315_9	1123508.JH636457_gene227	6.314e-23	115.0	COG5297@1|root,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_12,Ricin_B_lectin
SHD3_k127_5559315_18	246197.MXAN_0886	1.904e-05	58.0	COG0402@1|root,COG2374@1|root,COG0402@2|Bacteria,COG2374@2|Bacteria,1NFUA@1224|Proteobacteria,433MB@68525|delta/epsilon subdivisions,2WXJF@28221|Deltaproteobacteria,2YUGP@29|Myxococcales	28221|Deltaproteobacteria	F	Lamin Tail Domain	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,DUF4215,LTD,TSP_3
SHD3_k127_5559315_8	448385.sce5448	3.75e-33	142.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_5559315_7	215803.DB30_2315	1.887e-37	162.0	COG1520@1|root,COG3055@1|root,COG4676@1|root,COG1520@2|Bacteria,COG3055@2|Bacteria,COG4676@2|Bacteria,1NZI5@1224|Proteobacteria,43AH4@68525|delta/epsilon subdivisions,2X5X4@28221|Deltaproteobacteria,2Z37E@29|Myxococcales	1224|Proteobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,Kelch_1,Kelch_4,PKD,UPF0560
SHD3_k127_5559315_2	1313172.YM304_11060	6.029e-95	321.0	2DB7V@1|root,2Z7NX@2|Bacteria,2I9CJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5559315_6	1254432.SCE1572_20375	1.047e-52	198.0	2FIE8@1|root,34A6F@2|Bacteria,1P3KN@1224|Proteobacteria,431Y1@68525|delta/epsilon subdivisions,2WWQN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4423)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4423
SHD3_k127_5559315_5	583355.Caka_1050	2.61e-76	274.0	COG0857@1|root,COG0857@2|Bacteria,46UEZ@74201|Verrucomicrobia,3K761@414999|Opitutae	414999|Opitutae	C	AAA domain	-	-	-	ko:K06873	-	-	-	-	ko00000	-	-	-	AAA_26,DRTGG
SHD3_k127_5559315_10	1261545.MBE-HAL_0822	8.906e-22	100.0	COG1990@1|root,arCOG04228@2157|Archaea,2XYRE@28890|Euryarchaeota,23W1W@183963|Halobacteria	183963|Halobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K04794	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	PTH2
SHD3_k127_5559315_15	565033.GACE_2076	1.545e-11	71.0	COG0607@1|root,arCOG02021@2157|Archaea	2157|Archaea	P	COG0607 Rhodanese-related sulfurtransferase	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Rhodanese,THUMP,ThiI
SHD3_k127_5559315_11	439235.Dalk_3120	9.911e-17	87.0	COG1026@1|root,COG1026@2|Bacteria,1MVDJ@1224|Proteobacteria,42MRG@68525|delta/epsilon subdivisions,2WJ5Q@28221|Deltaproteobacteria,2MINB@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Peptidase M16C associated	PREP	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
SHD3_k127_5560942_3	870187.Thini_2559	4.435e-31	125.0	COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,45ZW2@72273|Thiotrichales	72273|Thiotrichales	G	Belongs to the pyruvate kinase family	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
SHD3_k127_5560942_1	448385.sce5989	1.359e-84	291.0	COG1968@1|root,COG1968@2|Bacteria,1MX02@1224|Proteobacteria,42N67@68525|delta/epsilon subdivisions,2WKPK@28221|Deltaproteobacteria,2Z316@29|Myxococcales	28221|Deltaproteobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
SHD3_k127_5560942_4	448385.sce2874	2.71e-15	89.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_5560942_0	1254432.SCE1572_26495	0.0	1116.0	COG4581@1|root,COG4581@2|Bacteria,1QUPR@1224|Proteobacteria,42NSH@68525|delta/epsilon subdivisions,2WKD7@28221|Deltaproteobacteria,2YUGZ@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DSHCT,DUF3516,Helicase_C
SHD3_k127_5560942_2	483219.LILAB_31530	1.087e-49	186.0	COG2095@1|root,COG2095@2|Bacteria,1MX5T@1224|Proteobacteria,42TIP@68525|delta/epsilon subdivisions,2WQA8@28221|Deltaproteobacteria,2YZB0@29|Myxococcales	28221|Deltaproteobacteria	U	UPF0056 inner membrane protein	marC	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
SHD3_k127_5570493_5	1123368.AUIS01000016_gene2555	8.247e-32	131.0	COG0737@1|root,COG0737@2|Bacteria,1Q977@1224|Proteobacteria,1RYXZ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	F	Belongs to the 5'-nucleotidase family	yfkN	-	3.1.3.6,3.1.4.16	ko:K01119	ko00230,ko00240,map00230,map00240	-	R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135	RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
SHD3_k127_5570493_4	404589.Anae109_0027	1.254e-32	129.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PocR,Response_reg,RsbRD_N
SHD3_k127_5570493_6	1121017.AUFG01000040_gene883	3.365e-07	59.0	COG0510@1|root,COG0510@2|Bacteria,2GRZD@201174|Actinobacteria,4FJEG@85021|Intrasporangiaceae	201174|Actinobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
SHD3_k127_5570493_0	1464048.JNZS01000018_gene2023	2.06e-100	341.0	COG2730@1|root,COG3469@1|root,COG2730@2|Bacteria,COG3469@2|Bacteria,2HW9X@201174|Actinobacteria,4DB85@85008|Micromonosporales	201174|Actinobacteria	G	Endoglucanase	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Cellulase,Glyco_hydro_12
SHD3_k127_5570493_3	251221.35212131	1.047e-33	146.0	2AVYW@1|root,31MT4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5570493_1	234267.Acid_4124	2.9e-51	203.0	COG1470@1|root,COG2931@1|root,COG1470@2|Bacteria,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CHB_HEX_C_1,CarboxypepD_reg,DUF11,DUF5122,Kelch_1,NPCBM_assoc,VCBS
SHD3_k127_5570493_2	1144313.PMI10_02561	4.347e-42	177.0	COG3405@1|root,COG3405@2|Bacteria,4NMI0@976|Bacteroidetes,1III7@117743|Flavobacteriia,2NUEH@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_8
SHD3_k127_5570493_7	1121403.AUCV01000030_gene2737	4.534e-06	59.0	2DSDS@1|root,33FPE@2|Bacteria,1Q5RQ@1224|Proteobacteria,431PE@68525|delta/epsilon subdivisions,2WWY9@28221|Deltaproteobacteria	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_557106_5	1192034.CAP_7613	7.545e-43	173.0	COG4105@1|root,COG4105@2|Bacteria	2|Bacteria	S	cell envelope organization	bamD	-	-	ko:K05807,ko:K08309	-	-	-	-	ko00000,ko01000,ko01011,ko02000	1.B.33.1	GH23	-	YfiO
SHD3_k127_557106_2	1192034.CAP_4442	1.484e-90	318.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_4442|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_557106_3	1192034.CAP_3979	4.607e-86	297.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_3979|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_557106_0	1242864.D187_002524	1.246e-172	554.0	COG1196@1|root,COG1196@2|Bacteria,1R3XQ@1224|Proteobacteria,42YF5@68525|delta/epsilon subdivisions,2WUDV@28221|Deltaproteobacteria,2YUHS@29|Myxococcales	28221|Deltaproteobacteria	D	5' nucleotidase family	surE2	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid
SHD3_k127_557106_1	1379281.AVAG01000009_gene617	6.724e-91	314.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,42RUT@68525|delta/epsilon subdivisions,2WR62@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	COG2189 Adenine specific DNA methylase Mod	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
SHD3_k127_557106_8	404589.Anae109_1523	3.237e-05	53.0	COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,42M64@68525|delta/epsilon subdivisions,2WIWS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	Heat shock 70 kDa protein	-	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70,PilZ
SHD3_k127_557106_6	448385.sce0848	1.468e-32	147.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce0848|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_557106_7	1254432.SCE1572_14920	1.014e-11	76.0	COG0457@1|root,COG0457@2|Bacteria	1254432.SCE1572_14920|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_557106_4	1192034.CAP_4239	7.44e-46	173.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	2|Bacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	FHA,HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_5600549_5	1158762.KB898041_gene1311	0.0001663	49.0	COG1664@1|root,COG1664@2|Bacteria,1PDPX@1224|Proteobacteria,1S9XY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Integral membrane protein CcmA involved in cell shape determination	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SHD3_k127_5600549_4	483219.LILAB_19665	6.147e-08	61.0	2ESNI@1|root,33K73@2|Bacteria,1Q2MV@1224|Proteobacteria,4388I@68525|delta/epsilon subdivisions,2X3I7@28221|Deltaproteobacteria,2YW7A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2378
SHD3_k127_5600549_0	1192034.CAP_1125	7.586e-131	434.0	COG0533@1|root,COG0533@2|Bacteria,1MU6S@1224|Proteobacteria,42MHX@68525|delta/epsilon subdivisions,2WIKS@28221|Deltaproteobacteria,2YTSN@29|Myxococcales	28221|Deltaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
SHD3_k127_5600549_2	290397.Adeh_0078	1.65e-42	166.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5600549_3	1192034.CAP_8873	3.209e-37	149.0	COG1716@1|root,COG1716@2|Bacteria,1PCHK@1224|Proteobacteria,438FP@68525|delta/epsilon subdivisions,2X3QN@28221|Deltaproteobacteria,2YWV4@29|Myxococcales	28221|Deltaproteobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
SHD3_k127_5602371_3	794903.OPIT5_18090	2.29e-97	325.0	2EDIX@1|root,337ET@2|Bacteria,46TG5@74201|Verrucomicrobia,3K76Q@414999|Opitutae	414999|Opitutae	S	tagaturonate epimerase	-	-	-	-	-	-	-	-	-	-	-	-	UxaE
SHD3_k127_5602371_0	234267.Acid_7084	3.447e-187	589.0	COG0524@1|root,COG0524@2|Bacteria,3Y3DE@57723|Acidobacteria	57723|Acidobacteria	G	PfkB domain protein	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
SHD3_k127_5602371_1	313628.LNTAR_19542	1.834e-185	591.0	COG1904@1|root,COG1904@2|Bacteria	2|Bacteria	G	glucuronate isomerase activity	uxaC	GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	iPC815.YPO0579,iSbBS512_1146.SbBS512_E3528	UxaC
SHD3_k127_5602371_9	204669.Acid345_4002	5.267e-51	192.0	COG1879@1|root,COG1879@2|Bacteria	2|Bacteria	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02058,ko:K10439	ko02010,ko02030,map02010,map02030	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SHD3_k127_5602371_11	1869.MB27_17115	1.16e-09	70.0	COG3266@1|root,COG4733@1|root,COG3266@2|Bacteria,COG4733@2|Bacteria,2I2V4@201174|Actinobacteria,4D9Z9@85008|Micromonosporales	201174|Actinobacteria	E	Parallel beta-helix repeats	pelX	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_2,CBM_35,CBM_6
SHD3_k127_5602371_7	316274.Haur_3461	2.302e-65	238.0	COG3866@1|root,COG5297@1|root,COG3866@2|Bacteria,COG5297@2|Bacteria,2G8UB@200795|Chloroflexi	2|Bacteria	G	CBD_II	-	-	4.2.2.2	ko:K01728	ko00040,ko02024,map00040,map02024	-	R02361,R06240	RC00049,RC00705	ko00000,ko00001,ko01000	-	-	-	CBM_2,Glyco_hydro_12,Pec_lyase_C
SHD3_k127_5602371_2	448385.sce1768	1.388e-103	355.0	2A4SI@1|root,30TDY@2|Bacteria,1PD6V@1224|Proteobacteria,435EQ@68525|delta/epsilon subdivisions,2X98Q@28221|Deltaproteobacteria,2Z2N2@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5602371_6	1254432.SCE1572_20660	2.828e-77	273.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_5602371_12	1236902.ANAS01000024_gene3160	2.983e-07	61.0	COG3266@1|root,COG3266@2|Bacteria,2I2V4@201174|Actinobacteria,4EGK1@85012|Streptosporangiales	201174|Actinobacteria	M	Right handed beta helix region	pelX	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,CBM_2,CBM_35,CBM_6
SHD3_k127_5602371_4	1192034.CAP_0103	2.373e-86	310.0	2AH4I@1|root,317E5@2|Bacteria,1PYQB@1224|Proteobacteria,435HF@68525|delta/epsilon subdivisions,2X99V@28221|Deltaproteobacteria,2Z2T7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5602371_10	84531.JMTZ01000168_gene725	1.469e-12	74.0	290G0@1|root,2ZN55@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5602371_8	448385.sce2072	2.146e-62	231.0	COG5164@1|root,COG5164@2|Bacteria,1R0C5@1224|Proteobacteria,43CUH@68525|delta/epsilon subdivisions,2X826@28221|Deltaproteobacteria,2Z24H@29|Myxococcales	28221|Deltaproteobacteria	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5602371_5	1192034.CAP_6318	9.835e-80	287.0	COG0484@1|root,COG2206@1|root,COG0484@2|Bacteria,COG2206@2|Bacteria,1QX6J@1224|Proteobacteria,43BZ5@68525|delta/epsilon subdivisions,2X79W@28221|Deltaproteobacteria,2Z3EH@29|Myxococcales	28221|Deltaproteobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DnaJ
SHD3_k127_5611687_7	1192034.CAP_0972	6.868e-46	173.0	COG0037@1|root,COG0037@2|Bacteria,1MW5Q@1224|Proteobacteria,42MMC@68525|delta/epsilon subdivisions,2WN12@28221|Deltaproteobacteria,2YTV2@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system	ttcA	-	-	ko:K14058	-	-	-	-	ko00000,ko03016	-	-	-	ATP_bind_3
SHD3_k127_5611687_10	448385.sce3099	5.397e-18	96.0	2AIUZ@1|root,319C5@2|Bacteria,1Q2AQ@1224|Proteobacteria,437XB@68525|delta/epsilon subdivisions,2X9R0@28221|Deltaproteobacteria,2Z0BZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5611687_4	448385.sce2902	3.699e-64	237.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,43BQ2@68525|delta/epsilon subdivisions,2WQ6X@28221|Deltaproteobacteria,2Z2WS@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SHD3_k127_5611687_3	1254432.SCE1572_23430	4.195e-100	341.0	COG0820@1|root,COG0820@2|Bacteria,1MUYK@1224|Proteobacteria,42N69@68525|delta/epsilon subdivisions,2WIUJ@28221|Deltaproteobacteria,2YWPQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the radical SAM superfamily. RlmN family	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
SHD3_k127_5611687_8	552811.Dehly_1197	3.296e-22	99.0	COG4826@1|root,COG4826@2|Bacteria,2GBWN@200795|Chloroflexi,34D50@301297|Dehalococcoidia	301297|Dehalococcoidia	M	SERine  Proteinase INhibitors	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Serpin
SHD3_k127_5611687_6	913325.N799_11240	5.155e-49	185.0	COG0518@1|root,COG0518@2|Bacteria,1MV9U@1224|Proteobacteria,1S49E@1236|Gammaproteobacteria,1X380@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
SHD3_k127_5611687_0	448385.sce7312	3.542e-171	552.0	COG0192@1|root,COG0192@2|Bacteria,1MUFQ@1224|Proteobacteria,42MFM@68525|delta/epsilon subdivisions,2WIQ3@28221|Deltaproteobacteria,2YUBT@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
SHD3_k127_5611687_2	639282.DEFDS_0424	7.647e-115	402.0	COG0643@1|root,COG0784@1|root,COG0643@2|Bacteria,COG0784@2|Bacteria,2GEP8@200930|Deferribacteres	200930|Deferribacteres	T	two-component system, chemotaxis family, sensor kinase CheA with response regulator domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,Response_reg
SHD3_k127_5611687_5	1122138.AQUZ01000001_gene1688	9.902e-59	220.0	COG1515@1|root,COG1515@2|Bacteria,2GJEZ@201174|Actinobacteria,4DUVR@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease V	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
SHD3_k127_5611687_9	1192034.CAP_4556	1.281e-19	93.0	COG0793@1|root,COG0793@2|Bacteria	2|Bacteria	M	Belongs to the peptidase S41A family	ctpB	GO:0003674,GO:0003824,GO:0004175,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009653,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030154,GO:0030288,GO:0030313,GO:0030435,GO:0031975,GO:0032502,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043603,GO:0043900,GO:0043902,GO:0043934,GO:0044237,GO:0044238,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1900190,GO:1900192,GO:1901564	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,PG_binding_1,Peptidase_S41
SHD3_k127_5611687_1	448385.sce2862	3.717e-149	482.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,42M6S@68525|delta/epsilon subdivisions,2WJU8@28221|Deltaproteobacteria,2YV2H@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
SHD3_k127_5621165_1	1121403.AUCV01000057_gene3054	4.713e-187	602.0	COG5297@1|root,COG5297@2|Bacteria,1NDMY@1224|Proteobacteria,4333K@68525|delta/epsilon subdivisions,2WXH7@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Cellulase N-terminal ig-like domain	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,CelD_N,Glyco_hydro_9
SHD3_k127_5621165_0	1254432.SCE1572_46485	3.677e-225	714.0	COG1032@1|root,COG1032@2|Bacteria,1MUG3@1224|Proteobacteria,42N0P@68525|delta/epsilon subdivisions,2WJCQ@28221|Deltaproteobacteria,2YU1P@29|Myxococcales	28221|Deltaproteobacteria	C	UPF0313 protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
SHD3_k127_5621165_2	349521.HCH_06576	1.252e-66	237.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Glyco_hydro_16,HemolysinCabind
SHD3_k127_5621165_3	398512.JQKC01000033_gene4972	1.316e-48	192.0	COG3405@1|root,COG3405@2|Bacteria,1VARG@1239|Firmicutes,24BG1@186801|Clostridia,3WK66@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	-	-	-	-	-	-	-	-	-	-	Dockerin_1,Glyco_hydro_8
SHD3_k127_562138_0	1121012.AUKX01000004_gene3566	1.289e-85	287.0	COG0277@1|root,COG0277@2|Bacteria,4NHFC@976|Bacteroidetes,1HYJ4@117743|Flavobacteriia,23FR5@178469|Arenibacter	976|Bacteroidetes	C	Berberine and berberine like	-	-	-	-	-	-	-	-	-	-	-	-	BBE,DUF805,FAD_binding_4
SHD3_k127_562138_1	59538.XP_005973263.1	1.054e-60	218.0	COG0451@1|root,2STIR@2759|Eukaryota	2759|Eukaryota	GM	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_562138_5	216594.MMAR_4002	6.084e-20	100.0	COG1028@1|root,COG1028@2|Bacteria,2I32I@201174|Actinobacteria,23FAN@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_562138_3	675635.Psed_0672	3.667e-24	103.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria,4EBN0@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
SHD3_k127_562138_2	641107.CDLVIII_4239	6.05e-48	191.0	COG5520@1|root,COG5520@2|Bacteria,1U8RG@1239|Firmicutes,248NT@186801|Clostridia,36H0Z@31979|Clostridiaceae	186801|Clostridia	G	dockerin type	xynC1	-	3.2.1.136	ko:K15924	-	-	-	-	ko00000,ko01000	-	GH5	-	CBM_2,CBM_4_9,CBM_6,Dockerin_1,Esterase,Glyco_hydro_30,Glyco_hydro_30C,Polysacc_deac_1,RicinB_lectin_2
SHD3_k127_562138_4	1120972.AUMH01000008_gene2001	5.491e-23	105.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,4HAAG@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21,3.2.1.52	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	M00628	R00022,R00026,R02558,R02887,R02985,R03527,R04949,R04998,R05963,R07809,R07810,R10035,R10039,R10040,R10831	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko00002,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
SHD3_k127_5625410_5	1378168.N510_01882	6.222e-05	50.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes	1239|Firmicutes	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
SHD3_k127_5625410_0	1121946.AUAX01000001_gene2439	8.79e-34	151.0	COG4677@1|root,COG4733@1|root,COG4677@2|Bacteria,COG4733@2|Bacteria,2I2SF@201174|Actinobacteria,4DA8U@85008|Micromonosporales	201174|Actinobacteria	G	Pectinesterase	-	-	3.1.1.11	ko:K01051	ko00040,ko01100,map00040,map01100	M00081	R02362	RC00460,RC00461	ko00000,ko00001,ko00002,ko01000	-	-	-	Pectinesterase
SHD3_k127_5625410_4	903818.KI912269_gene161	1.165e-06	58.0	COG2865@1|root,COG2865@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
SHD3_k127_5625410_2	448385.sce2914	6.358e-26	112.0	COG0457@1|root,COG0457@2|Bacteria,1P0DI@1224|Proteobacteria,431RN@68525|delta/epsilon subdivisions,2WWCP@28221|Deltaproteobacteria,2Z3IU@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5630254_9	944481.JAFP01000001_gene1126	6.728e-34	143.0	COG2885@1|root,COG2885@2|Bacteria,1R0MX@1224|Proteobacteria,430Y0@68525|delta/epsilon subdivisions,2WVRR@28221|Deltaproteobacteria,2M6W6@213113|Desulfurellales	28221|Deltaproteobacteria	M	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
SHD3_k127_5630254_2	1449347.JQLN01000006_gene3085	2.902e-96	328.0	COG2730@1|root,COG2730@2|Bacteria,2HW9X@201174|Actinobacteria,2M0K4@2063|Kitasatospora	201174|Actinobacteria	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Cellulase
SHD3_k127_5630254_12	251229.Chro_1923	2.194e-19	102.0	COG2006@1|root,COG2006@2|Bacteria,1G1NA@1117|Cyanobacteria,3VIJ1@52604|Pleurocapsales	1117|Cyanobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_5630254_11	1121440.AUMA01000003_gene2990	7.101e-23	107.0	COG1259@1|root,COG1259@2|Bacteria,1RFFV@1224|Proteobacteria,42SCI@68525|delta/epsilon subdivisions,2WPWT@28221|Deltaproteobacteria,2M8KC@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
SHD3_k127_5630254_13	309807.SRU_2552	2.712e-18	92.0	2CDT8@1|root,33C3R@2|Bacteria,4NXI8@976|Bacteroidetes	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5630254_15	448385.sce4732	6.744e-09	64.0	COG5549@1|root,COG5549@2|Bacteria	2|Bacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SHD3_k127_5630254_10	448385.sce3514	1.096e-25	119.0	COG3921@1|root,COG3921@2|Bacteria,1QASS@1224|Proteobacteria,4359Z@68525|delta/epsilon subdivisions,2WZM2@28221|Deltaproteobacteria,2Z2CT@29|Myxococcales	28221|Deltaproteobacteria	S	Extensin-like protein C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Extensin-like_C
SHD3_k127_5630254_14	159749.K0T0B9	7.436e-11	72.0	COG1404@1|root,KOG1153@2759|Eukaryota,2XCPP@2836|Bacillariophyta	2759|Eukaryota	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	EGF_CA,Peptidase_S8
SHD3_k127_5630254_0	448385.sce1684	6.275e-237	764.0	COG0457@1|root,COG0457@2|Bacteria,1Q385@1224|Proteobacteria,433YW@68525|delta/epsilon subdivisions,2X44A@28221|Deltaproteobacteria,2YY7W@29|Myxococcales	28221|Deltaproteobacteria	E	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
SHD3_k127_5630254_6	517417.Cpar_0408	5.376e-55	203.0	COG1912@1|root,COG1912@2|Bacteria,1FDZ8@1090|Chlorobi	1090|Chlorobi	M	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
SHD3_k127_5630254_7	1121468.AUBR01000009_gene2126	3.346e-45	175.0	COG0655@1|root,COG0655@2|Bacteria,1TRAC@1239|Firmicutes,24APM@186801|Clostridia,42HAM@68295|Thermoanaerobacterales	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
SHD3_k127_5630254_3	926560.KE387027_gene352	1.262e-81	284.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1WMXM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5630254_4	1532557.JL37_06595	3.829e-68	243.0	COG0386@1|root,COG0386@2|Bacteria,1RD1R@1224|Proteobacteria,2VR4K@28216|Betaproteobacteria,3T3WM@506|Alcaligenaceae	28216|Betaproteobacteria	O	Belongs to the glutathione peroxidase family	bsaA	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
SHD3_k127_5630254_8	1157708.KB907450_gene6312	9.946e-41	163.0	COG0627@1|root,COG0627@2|Bacteria,1MY73@1224|Proteobacteria,2VS12@28216|Betaproteobacteria,4AF76@80864|Comamonadaceae	28216|Betaproteobacteria	S	Serine hydrolase involved in the detoxification of formaldehyde	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SHD3_k127_5630254_16	749414.SBI_04631	8.859e-07	63.0	COG0488@1|root,COG2319@1|root,COG0488@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria	201174|Actinobacteria	F	WD-40 repeat	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC4_WD40,HTH_3,HTH_31,WD40
SHD3_k127_5630254_5	717785.HYPMC_1421	1.098e-56	199.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,2VF0E@28211|Alphaproteobacteria,3N9CH@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	M	FKBP-type peptidyl-prolyl cis-trans isomerase	MA20_44950	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Rhodanese
SHD3_k127_5630254_1	504472.Slin_5373	1.654e-119	391.0	COG0702@1|root,COG0702@2|Bacteria,4NIHJ@976|Bacteroidetes,47M40@768503|Cytophagia	976|Bacteroidetes	GM	NmrA-like family	-	-	-	-	-	-	-	-	-	-	-	-	NmrA
SHD3_k127_5632033_1	215803.DB30_8691	3.652e-40	169.0	COG1413@1|root,COG1413@2|Bacteria,1P8HR@1224|Proteobacteria,438W3@68525|delta/epsilon subdivisions,2X41M@28221|Deltaproteobacteria,2YXYY@29|Myxococcales	28221|Deltaproteobacteria	C	Lipoprotein amino terminal region	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_5632033_4	1123508.JH636443_gene4803	5.166e-24	109.0	COG1714@1|root,COG1714@2|Bacteria,2J3VC@203682|Planctomycetes	203682|Planctomycetes	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
SHD3_k127_5632033_2	357808.RoseRS_4272	6.639e-35	144.0	COG2931@1|root,COG3210@1|root,COG2931@2|Bacteria,COG3210@2|Bacteria,2G88I@200795|Chloroflexi,3780V@32061|Chloroflexia	32061|Chloroflexia	U	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5637269_6	1125863.JAFN01000001_gene2926	6.427e-78	278.0	COG1122@1|root,COG1122@2|Bacteria,1N5X0@1224|Proteobacteria,43ADF@68525|delta/epsilon subdivisions,2WMEV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	part of an ABC transporter complex. Responsible for energy coupling to the transport system	-	-	-	ko:K02006,ko:K16787	ko02010,map02010	M00245,M00246,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
SHD3_k127_5637269_8	1125863.JAFN01000001_gene2925	2.193e-56	211.0	COG0619@1|root,COG0619@2|Bacteria,1R2DN@1224|Proteobacteria,43B6A@68525|delta/epsilon subdivisions,2X6JT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	-	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
SHD3_k127_5637269_5	398767.Glov_2769	2.532e-80	278.0	COG0310@1|root,COG0310@2|Bacteria,1R70A@1224|Proteobacteria,42NXD@68525|delta/epsilon subdivisions,2WKCZ@28221|Deltaproteobacteria,43U1E@69541|Desulfuromonadales	28221|Deltaproteobacteria	P	PDGLE domain	nikMN	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	iAF987.Gmet_2441	CbiM,PDGLE
SHD3_k127_5637269_10	765420.OSCT_1275	3.155e-36	157.0	COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia	32061|Chloroflexia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5637269_4	1192034.CAP_3979	4.359e-89	308.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_3979|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5637269_11	391625.PPSIR1_34113	1.012e-30	136.0	COG2200@1|root,COG2204@1|root,COG2200@2|Bacteria,COG2204@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2Z1P1@29|Myxococcales	28221|Deltaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
SHD3_k127_5637269_12	640081.Dsui_1894	9.483e-08	63.0	2DKZI@1|root,310D6@2|Bacteria,1QV1U@1224|Proteobacteria,2VQ0G@28216|Betaproteobacteria,2KW5E@206389|Rhodocyclales	206389|Rhodocyclales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5637269_9	1254432.SCE1572_21910	3.993e-50	188.0	COG4636@1|root,COG4636@2|Bacteria,1Q2ER@1224|Proteobacteria,4380F@68525|delta/epsilon subdivisions,2X3AI@28221|Deltaproteobacteria,2YV50@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_5637269_2	1192034.CAP_3665	7.255e-156	503.0	COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria	1224|Proteobacteria	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Mrr_cat,N6_N4_Mtase
SHD3_k127_5637269_0	1192034.CAP_0894	2.558e-192	625.0	COG0827@1|root,COG1002@1|root,COG0827@2|Bacteria,COG1002@2|Bacteria,1NM9N@1224|Proteobacteria	1224|Proteobacteria	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
SHD3_k127_5637269_1	1210884.HG799463_gene9303	2.042e-160	514.0	COG0579@1|root,COG0579@2|Bacteria,2IX3W@203682|Planctomycetes	203682|Planctomycetes	S	FAD dependent oxidoreductase	-	-	-	ko:K15736	-	-	-	-	ko00000,ko01000	-	-	-	DAO
SHD3_k127_5637269_3	414684.RC1_0837	3.166e-113	376.0	COG1940@1|root,COG1940@2|Bacteria,1MU94@1224|Proteobacteria,2TRRU@28211|Alphaproteobacteria,2JQ4F@204441|Rhodospirillales	204441|Rhodospirillales	GK	ROK family	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
SHD3_k127_5637269_7	1254432.SCE1572_10990	7.59e-59	220.0	COG1716@1|root,COG2199@1|root,COG1716@2|Bacteria,COG3706@2|Bacteria,1MZV7@1224|Proteobacteria,4302C@68525|delta/epsilon subdivisions,2WVBW@28221|Deltaproteobacteria,2YUSZ@29|Myxococcales	28221|Deltaproteobacteria	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA,GGDEF,Yop-YscD_cpl
SHD3_k127_5637269_13	391625.PPSIR1_16510	5.36e-06	54.0	COG0823@1|root,COG3266@1|root,COG0823@2|Bacteria,COG3266@2|Bacteria,1RI0N@1224|Proteobacteria,43CN9@68525|delta/epsilon subdivisions,2X7VJ@28221|Deltaproteobacteria,2Z048@29|Myxococcales	28221|Deltaproteobacteria	U	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14
SHD3_k127_5639570_2	1254432.SCE1572_05290	2.507e-21	98.0	COG5640@1|root,COG5640@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,CW_binding_2,FTP,FlgD_ig,PPC,Peptidase_M4,Peptidase_M4_C,RicinB_lectin_2,SBBP,TIG,Trypsin,VCBS
SHD3_k127_5639570_4	765910.MARPU_08480	3.482e-07	61.0	COG0845@1|root,COG0845@2|Bacteria,1MVAS@1224|Proteobacteria,1RPBZ@1236|Gammaproteobacteria,1WWE4@135613|Chromatiales	135613|Chromatiales	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	HlyD_D23
SHD3_k127_5639570_0	1192034.CAP_8124	7.113e-274	879.0	COG3696@1|root,COG3696@2|Bacteria,1NUIV@1224|Proteobacteria,42NCZ@68525|delta/epsilon subdivisions,2WK3X@28221|Deltaproteobacteria,2YUB0@29|Myxococcales	28221|Deltaproteobacteria	P	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K07787	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4	-	iAF987.Gmet_1547	ACR_tran
SHD3_k127_5639570_1	448385.sce3735	6.814e-78	265.0	COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,42M8G@68525|delta/epsilon subdivisions,2WIYB@28221|Deltaproteobacteria,2YUGJ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
SHD3_k127_5645559_3	1173029.JH980292_gene2288	0.000833	52.0	COG0457@1|root,COG0457@2|Bacteria,1GD9N@1117|Cyanobacteria,1HH3D@1150|Oscillatoriales	1117|Cyanobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_11,TPR_16,TPR_2,TPR_8
SHD3_k127_5645559_1	1254432.SCE1572_07785	5.285e-71	254.0	COG2006@1|root,COG2006@2|Bacteria,1QMGX@1224|Proteobacteria,42PRJ@68525|delta/epsilon subdivisions,2WMFN@28221|Deltaproteobacteria,2Z073@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
SHD3_k127_5645559_0	215803.DB30_5758	5.497e-89	331.0	COG0419@1|root,COG0419@2|Bacteria,1MVTQ@1224|Proteobacteria,42NVV@68525|delta/epsilon subdivisions,2WJIZ@28221|Deltaproteobacteria,2YWNV@29|Myxococcales	28221|Deltaproteobacteria	L	COG0419 ATPase involved in DNA repair	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
SHD3_k127_5645559_2	1192759.AKIB01000020_gene3083	2.342e-13	79.0	COG0420@1|root,COG0420@2|Bacteria,1MVV6@1224|Proteobacteria,2TV97@28211|Alphaproteobacteria,2K6PZ@204457|Sphingomonadales	204457|Sphingomonadales	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	-	-	-	-	-	-	-	-	-	Metallophos,SbcD_C
SHD3_k127_5650470_1	1206733.BAGC01000035_gene3691	4.701e-90	317.0	COG1053@1|root,COG1053@2|Bacteria,2IEP3@201174|Actinobacteria,4FX2Y@85025|Nocardiaceae	201174|Actinobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
SHD3_k127_5650470_0	203122.Sde_2929	1.688e-151	494.0	COG2730@1|root,COG2730@2|Bacteria,1N21U@1224|Proteobacteria,1RRB0@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_6,Cellulase
SHD3_k127_5650470_3	1158318.ATXC01000001_gene710	1.201e-27	125.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126,ko:K19292	-	-	-	-	ko00000	-	-	-	DUF900,Sel1
SHD3_k127_5650470_2	449447.MAE_21550	9.481e-42	171.0	COG2931@1|root,COG2931@2|Bacteria	2|Bacteria	Q	calcium- and calmodulin-responsive adenylate cyclase activity	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,DUF11,HemolysinCabind,LTD,Peptidase_M10_C
SHD3_k127_565145_0	448385.sce6517	5.845e-281	891.0	COG1032@1|root,COG5011@1|root,COG1032@2|Bacteria,COG5011@2|Bacteria,1MV5G@1224|Proteobacteria,42MPT@68525|delta/epsilon subdivisions,2WJG9@28221|Deltaproteobacteria,2YUJ4@29|Myxococcales	28221|Deltaproteobacteria	C	SMART Elongator protein 3 MiaB NifB	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344,Radical_SAM
SHD3_k127_565145_1	448385.sce2640	1.188e-139	458.0	2CF5E@1|root,2ZFJ4@2|Bacteria,1Q1S5@1224|Proteobacteria,437FB@68525|delta/epsilon subdivisions,2X2MW@28221|Deltaproteobacteria,2YTW7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_565145_2	290397.Adeh_0078	1.903e-29	128.0	2A9VF@1|root,30Z3B@2|Bacteria,1PKZS@1224|Proteobacteria,435JG@68525|delta/epsilon subdivisions,2WZXJ@28221|Deltaproteobacteria,2Z0YG@29|Myxococcales	290397.Adeh_0078|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5651572_20	224324.aq_951	4.807e-10	68.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,2G3JS@200783|Aquificae	200783|Aquificae	E	Prephenate dehydratase	pheA	GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
SHD3_k127_5651572_15	350058.Mvan_1002	9.257e-16	81.0	COG3255@1|root,COG3255@2|Bacteria	2|Bacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
SHD3_k127_5651572_0	448385.sce1272	7.44e-172	556.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	enhA_1	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
SHD3_k127_5651572_18	1192034.CAP_1747	1.099e-11	78.0	COG3170@1|root,COG3170@2|Bacteria,1QX3V@1224|Proteobacteria,43BWB@68525|delta/epsilon subdivisions,2X773@28221|Deltaproteobacteria,2YVT2@29|Myxococcales	28221|Deltaproteobacteria	NU	zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_4
SHD3_k127_5651572_14	290397.Adeh_0467	1.036e-17	91.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	amcY	GO:0005575,GO:0005623,GO:0042597,GO:0044464	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
SHD3_k127_5651572_19	1122927.KB895419_gene2329	3.726e-11	68.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,26ZR6@186822|Paenibacillaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	cccB	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
SHD3_k127_5651572_1	404589.Anae109_2886	2.896e-149	484.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria,2YZRV@29|Myxococcales	28221|Deltaproteobacteria	C	Aldo/keto reductase family	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SHD3_k127_5651572_7	1192034.CAP_4980	3.084e-44	163.0	COG1664@1|root,COG1664@2|Bacteria,1N7TF@1224|Proteobacteria,42VWZ@68525|delta/epsilon subdivisions,2WRPF@28221|Deltaproteobacteria,2YVIX@29|Myxococcales	28221|Deltaproteobacteria	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SHD3_k127_5651572_2	448385.sce2847	1.365e-140	456.0	COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria,2YVAA@29|Myxococcales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_0069	GGDEF,Response_reg
SHD3_k127_5651572_3	1278073.MYSTI_05929	5.859e-140	459.0	COG2204@1|root,COG2204@2|Bacteria,1MU0N@1224|Proteobacteria,42M03@68525|delta/epsilon subdivisions,2WIT0@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	two component, sigma54 specific, transcriptional regulator, Fis family	hsfA	-	-	ko:K07713,ko:K07714	ko02020,map02020	M00499,M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
SHD3_k127_5651572_4	1192034.CAP_4613	9.308e-127	425.0	COG1538@1|root,COG1538@2|Bacteria,1QWWG@1224|Proteobacteria,42PD6@68525|delta/epsilon subdivisions,2WK6G@28221|Deltaproteobacteria,2Z1AQ@29|Myxococcales	28221|Deltaproteobacteria	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
SHD3_k127_5651572_6	1254432.SCE1572_23515	6.581e-105	366.0	COG3177@1|root,COG3177@2|Bacteria,1Q2H9@1224|Proteobacteria,4383Y@68525|delta/epsilon subdivisions,2X3DX@28221|Deltaproteobacteria,2YVMK@29|Myxococcales	28221|Deltaproteobacteria	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
SHD3_k127_5651572_5	448385.sce1069	1.234e-110	368.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria,2YU2H@29|Myxococcales	28221|Deltaproteobacteria	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
SHD3_k127_5651572_11	1192034.CAP_5063	2.743e-22	99.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nifU	-	-	ko:K07126,ko:K13819	-	-	-	-	ko00000	-	-	-	Fer2_BFD,NifU,NifU_N
SHD3_k127_5651572_13	1304874.JAFY01000005_gene1294	1.219e-19	96.0	COG0228@1|root,COG0228@2|Bacteria,3TBDH@508458|Synergistetes	508458|Synergistetes	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
SHD3_k127_5651572_10	644282.Deba_3167	1.715e-22	100.0	COG1837@1|root,COG1837@2|Bacteria,1N7IX@1224|Proteobacteria,42TXI@68525|delta/epsilon subdivisions,2WQBS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Belongs to the UPF0109 family	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
SHD3_k127_5651572_12	1254432.SCE1572_27120	4.02e-21	101.0	COG0806@1|root,COG0806@2|Bacteria,1MWQR@1224|Proteobacteria,42TGI@68525|delta/epsilon subdivisions,2WQJU@28221|Deltaproteobacteria,2YW17@29|Myxococcales	28221|Deltaproteobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
SHD3_k127_5651572_8	448385.sce4436	6.534e-44	167.0	COG0336@1|root,COG0336@2|Bacteria,1MUN1@1224|Proteobacteria,42P8R@68525|delta/epsilon subdivisions,2WKIR@28221|Deltaproteobacteria,2YV3E@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Methyltrn_RNA_4,tRNA_m1G_MT
SHD3_k127_5651942_3	448385.sce0400	7.985e-41	164.0	COG3266@1|root,COG3266@2|Bacteria,1Q2HB@1224|Proteobacteria,43840@68525|delta/epsilon subdivisions,2X9WR@28221|Deltaproteobacteria,2YVMS@29|Myxococcales	28221|Deltaproteobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5651942_2	1254432.SCE1572_02980	4.601e-74	260.0	2BQU7@1|root,32JQZ@2|Bacteria,1Q2FE@1224|Proteobacteria,4381B@68525|delta/epsilon subdivisions,2X05S@28221|Deltaproteobacteria,2YV8M@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_FA
SHD3_k127_5651942_1	1254432.SCE1572_02975	5.228e-98	334.0	COG0682@1|root,COG0682@2|Bacteria,1MVE3@1224|Proteobacteria,42M2I@68525|delta/epsilon subdivisions,2WNPT@28221|Deltaproteobacteria,2YXEG@29|Myxococcales	28221|Deltaproteobacteria	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	-	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
SHD3_k127_5651942_0	215803.DB30_4304	3.371e-227	713.0	COG1216@1|root,COG4976@1|root,COG1216@2|Bacteria,COG4976@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
SHD3_k127_5651942_4	1340493.JNIF01000004_gene1024	4.486e-22	111.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT,PMT_2
SHD3_k127_5651942_6	7739.XP_002613281.1	0.0001406	54.0	KOG4729@1|root,KOG4729@2759|Eukaryota	7739.XP_002613281.1|-	O	carbohydrate binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_565284_0	290397.Adeh_2580	3.396e-174	555.0	COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,42NGD@68525|delta/epsilon subdivisions,2WJDC@28221|Deltaproteobacteria,2YZAF@29|Myxococcales	28221|Deltaproteobacteria	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SHD3_k127_565284_2	290397.Adeh_2581	2.896e-123	411.0	COG1007@1|root,COG1007@2|Bacteria,1MV56@1224|Proteobacteria,42P7Z@68525|delta/epsilon subdivisions,2WKS0@28221|Deltaproteobacteria,2YXGF@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
SHD3_k127_565284_3	1254432.SCE1572_48410	7.375e-78	274.0	COG0003@1|root,COG0003@2|Bacteria,1NA7C@1224|Proteobacteria,42V2J@68525|delta/epsilon subdivisions,2WS25@28221|Deltaproteobacteria,2YUZS@29|Myxococcales	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SHD3_k127_565284_1	870187.Thini_3652	3.859e-161	520.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria,460F9@72273|Thiotrichales	72273|Thiotrichales	C	Aldehyde dehydrogenase family	-	-	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
SHD3_k127_5669787_0	1283300.ATXB01000001_gene2252	4.795e-159	508.0	COG1262@1|root,COG1262@2|Bacteria,1MUNC@1224|Proteobacteria,1RQI4@1236|Gammaproteobacteria,1XG2U@135618|Methylococcales	135618|Methylococcales	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,FGE-sulfatase
SHD3_k127_5669787_2	323848.Nmul_A1925	3.377e-92	316.0	COG4301@1|root,COG4301@2|Bacteria,1MUCG@1224|Proteobacteria,2VJHK@28216|Betaproteobacteria,373E1@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Histidine-specific methyltransferase, SAM-dependent	egtD	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_33
SHD3_k127_5669787_1	1356852.N008_00500	1.116e-114	376.0	28HGI@1|root,2Z7SC@2|Bacteria,4NJUF@976|Bacteroidetes,47PDE@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5669787_3	398527.Bphyt_5493	9.026e-39	147.0	COG5207@1|root,COG5207@2|Bacteria,1RHKT@1224|Proteobacteria,2W3ZK@28216|Betaproteobacteria,1K983@119060|Burkholderiaceae	28216|Betaproteobacteria	O	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	zf-UBP
SHD3_k127_5682518_0	344747.PM8797T_02909	2.575e-231	777.0	COG0642@1|root,COG1352@1|root,COG2202@1|root,COG5000@1|root,COG5002@1|root,COG1352@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,2IWSR@203682|Planctomycetes	203682|Planctomycetes	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,CheR,CheR_N,HATPase_c,HisKA,PAS,PAS_10,PAS_3,PAS_4,Response_reg
SHD3_k127_5704830_1	153721.MYP_1794	0.0006611	48.0	COG3291@1|root,COG3405@1|root,COG3291@2|Bacteria,COG3405@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 8 (cellulase D) family	-	-	2.4.1.12,3.2.1.156,3.2.1.4	ko:K00694,ko:K15531,ko:K20542	ko00500,ko01100,ko02026,map00500,map01100,map02026	-	R02889	RC00005	ko00000,ko00001,ko01000,ko01003,ko02000	4.D.3.1.2,4.D.3.1.5,4.D.3.1.6	GH8,GT2	-	CHU_C,Glyco_hydro_8,PKD
SHD3_k127_5704830_0	1144313.PMI10_02561	1.218e-50	204.0	COG3405@1|root,COG3405@2|Bacteria,4NMI0@976|Bacteroidetes,1III7@117743|Flavobacteriia,2NUEH@237|Flavobacterium	976|Bacteroidetes	G	Glycosyl hydrolases family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_8
SHD3_k127_5709510_2	391612.CY0110_25938	7.174e-36	140.0	COG0065@1|root,COG0065@2|Bacteria,1G1J0@1117|Cyanobacteria,3KGCN@43988|Cyanothece	1117|Cyanobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
SHD3_k127_5709510_3	1894.JOER01000001_gene5206	2.427e-06	55.0	COG1846@1|root,COG1846@2|Bacteria,2II35@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
SHD3_k127_5709510_0	997346.HMPREF9374_0159	9.435e-265	835.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,4H9SU@91061|Bacilli,27BJQ@186824|Thermoactinomycetaceae	91061|Bacilli	T	5TM C-terminal transporter carbon starvation CstA	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
SHD3_k127_5709510_1	1254432.SCE1572_22470	1.968e-170	544.0	COG0119@1|root,COG0119@2|Bacteria,1MUNQ@1224|Proteobacteria,42MAV@68525|delta/epsilon subdivisions,2WJC9@28221|Deltaproteobacteria,2YW7U@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the alpha-IPM synthase homocitrate synthase family	cimA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
SHD3_k127_5709901_3	448385.sce8989	1.504e-81	286.0	COG1506@1|root,COG5184@1|root,COG1506@2|Bacteria,COG5184@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215
SHD3_k127_5709901_5	1192034.CAP_5425	5.379e-67	239.0	COG4856@1|root,COG4856@2|Bacteria,1QARN@1224|Proteobacteria,4359B@68525|delta/epsilon subdivisions,2X973@28221|Deltaproteobacteria,2Z2BE@29|Myxococcales	28221|Deltaproteobacteria	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
SHD3_k127_5709901_2	1254432.SCE1572_44070	1.196e-86	300.0	COG1624@1|root,COG3266@1|root,COG1624@2|Bacteria,COG3266@2|Bacteria,1PEQT@1224|Proteobacteria,42P5A@68525|delta/epsilon subdivisions,2WKPP@28221|Deltaproteobacteria,2YV5I@29|Myxococcales	28221|Deltaproteobacteria	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
SHD3_k127_5709901_4	1192034.CAP_5427	1.353e-75	265.0	COG0294@1|root,COG0294@2|Bacteria,1MUIR@1224|Proteobacteria,42MMY@68525|delta/epsilon subdivisions,2WIXA@28221|Deltaproteobacteria,2YVIZ@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15,2.7.6.3	ko:K00796,ko:K13941	ko00790,ko01100,map00790,map01100	M00126,M00840,M00841	R03066,R03067,R03503	RC00002,RC00017,RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
SHD3_k127_5709901_0	1192034.CAP_5428	1.672e-188	608.0	COG1480@1|root,COG1480@2|Bacteria,1NCY5@1224|Proteobacteria,42MI9@68525|delta/epsilon subdivisions,2WJI1@28221|Deltaproteobacteria,2YUW7@29|Myxococcales	28221|Deltaproteobacteria	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,7TMR-HDED,HD
SHD3_k127_5709901_11	757424.Hsero_3426	6.543e-19	89.0	2DPYH@1|root,333YR@2|Bacteria,1NF9G@1224|Proteobacteria	1224|Proteobacteria	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
SHD3_k127_5709901_10	631362.Thi970DRAFT_00210	1.695e-26	118.0	2E3EN@1|root,32YDN@2|Bacteria,1N7N7@1224|Proteobacteria,1SCSD@1236|Gammaproteobacteria,1WZ7T@135613|Chromatiales	135613|Chromatiales	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
SHD3_k127_5709901_9	644282.Deba_2158	2.613e-36	154.0	COG4753@1|root,COG5002@1|root,COG4753@2|Bacteria,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,42QJF@68525|delta/epsilon subdivisions,2WJ9D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS,PAS_4,Response_reg
SHD3_k127_5709901_6	377629.TERTU_0094	9.963e-61	221.0	COG0627@1|root,COG0627@2|Bacteria,1QR76@1224|Proteobacteria,1RU21@1236|Gammaproteobacteria,2PQC4@256005|Alteromonadales genera incertae sedis	1236|Gammaproteobacteria	S	Esterase PHB depolymerase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
SHD3_k127_5709901_7	448385.sce2921	2.157e-58	227.0	COG0457@1|root,COG2956@1|root,COG3071@1|root,COG0457@2|Bacteria,COG2956@2|Bacteria,COG3071@2|Bacteria,1MVIW@1224|Proteobacteria,437VP@68525|delta/epsilon subdivisions,2WWNT@28221|Deltaproteobacteria,2YUC4@29|Myxococcales	28221|Deltaproteobacteria	G	repeat protein	agmK	-	-	-	-	-	-	-	-	-	-	-	TPR_19,TPR_6,TPR_7,TPR_8
SHD3_k127_5709901_1	1444712.BN1013_00669	4.553e-127	416.0	COG0306@1|root,COG0306@2|Bacteria,2JH20@204428|Chlamydiae	204428|Chlamydiae	P	Phosphate transporter family	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
SHD3_k127_5709901_8	96561.Dole_2749	3.295e-48	183.0	COG1181@1|root,COG1181@2|Bacteria,1MX3I@1224|Proteobacteria,42SA1@68525|delta/epsilon subdivisions,2WNIR@28221|Deltaproteobacteria,2MIAX@213118|Desulfobacterales	28221|Deltaproteobacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C
SHD3_k127_5710865_1	446471.Xcel_2665	3.213e-92	309.0	COG1874@1|root,COG1874@2|Bacteria,2IE1F@201174|Actinobacteria	201174|Actinobacteria	G	Beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4978,Glyco_hydro_35,Glyco_hydro_42,RicinB_lectin_2
SHD3_k127_5710865_3	179408.Osc7112_1573	2.054e-10	70.0	28JE3@1|root,2Z98B@2|Bacteria,1G13G@1117|Cyanobacteria,1H9TN@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_5710865_0	1168034.FH5T_01625	2.164e-146	475.0	COG5557@1|root,COG5557@2|Bacteria	2|Bacteria	C	Polysulphide reductase, NrfD	hmcC	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	NrfD
SHD3_k127_5710865_2	1168034.FH5T_01630	4.786e-88	302.0	COG0437@1|root,COG0437@2|Bacteria,4NIEP@976|Bacteroidetes	976|Bacteroidetes	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_4
SHD3_k127_580861_9	1254432.SCE1572_43615	9.751e-47	171.0	COG5611@1|root,COG5611@2|Bacteria	2|Bacteria	S	PIN domain	vapC	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_580861_5	448385.sce8309	2.766e-69	247.0	COG0479@1|root,COG0479@2|Bacteria,1MVHS@1224|Proteobacteria,42M2J@68525|delta/epsilon subdivisions,2WJMH@28221|Deltaproteobacteria,2YWFJ@29|Myxococcales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240,ko:K00245	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_10,Fer4_8
SHD3_k127_580861_3	1254432.SCE1572_48440	1.213e-114	392.0	COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,42M81@68525|delta/epsilon subdivisions,2WJXY@28221|Deltaproteobacteria,2YWNM@29|Myxococcales	28221|Deltaproteobacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SHD3_k127_580861_7	1254432.SCE1572_48435	6.808e-54	199.0	COG2009@1|root,COG2009@2|Bacteria,1R7RY@1224|Proteobacteria,4329Z@68525|delta/epsilon subdivisions,2WYFY@28221|Deltaproteobacteria,2Z20Y@29|Myxococcales	28221|Deltaproteobacteria	C	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
SHD3_k127_580861_11	448385.sce8304	2.147e-41	160.0	COG0802@1|root,COG0802@2|Bacteria,1RGYU@1224|Proteobacteria,42VU4@68525|delta/epsilon subdivisions,2WQBA@28221|Deltaproteobacteria,2YW3H@29|Myxococcales	28221|Deltaproteobacteria	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	yjeE	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
SHD3_k127_580861_4	448385.sce8301	5.694e-91	308.0	COG0767@1|root,COG0767@2|Bacteria,1MVPN@1224|Proteobacteria,42MR1@68525|delta/epsilon subdivisions,2WKC9@28221|Deltaproteobacteria,2YV04@29|Myxococcales	28221|Deltaproteobacteria	Q	COG0767 ABC-type transport system involved in resistance to organic solvents, permease component	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
SHD3_k127_580861_2	519989.ECTPHS_13452	4.022e-123	406.0	COG0438@1|root,COG0438@2|Bacteria,1MWSZ@1224|Proteobacteria,1RMQP@1236|Gammaproteobacteria,1WXA8@135613|Chromatiales	135613|Chromatiales	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
SHD3_k127_580861_1	1411123.JQNH01000001_gene3594	2.63e-180	592.0	COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2TQK2@28211|Alphaproteobacteria	28211|Alphaproteobacteria	G	Amylo-alpha-1,6-glucosidase	MA20_17380	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,GDE_C,GDE_N_bis
SHD3_k127_580861_6	292564.Cyagr_2459	4.156e-68	239.0	COG0518@1|root,COG0518@2|Bacteria,1GFCZ@1117|Cyanobacteria,22SY9@167375|Cyanobium	1117|Cyanobacteria	F	F COG0518 GMP synthase - Glutamine amidotransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	GATase
SHD3_k127_580861_12	1144275.COCOR_03999	6.177e-26	118.0	28PB0@1|root,2ZC40@2|Bacteria,1Q1BW@1224|Proteobacteria,4376A@68525|delta/epsilon subdivisions,2X3U5@28221|Deltaproteobacteria,2YX4A@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_580861_0	448385.sce1029	0.0	1045.0	COG1033@1|root,COG4258@1|root,COG1033@2|Bacteria,COG4258@2|Bacteria,1QX7Z@1224|Proteobacteria,43C13@68525|delta/epsilon subdivisions,2X7BR@28221|Deltaproteobacteria,2YU55@29|Myxococcales	28221|Deltaproteobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
SHD3_k127_580861_10	240015.ACP_1703	6.811e-44	170.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.197	ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,TPMT
SHD3_k127_583662_1	59374.Fisuc_2943	9.841e-63	231.0	COG5520@1|root,COG5520@2|Bacteria	59374.Fisuc_2943|-	M	Belongs to the glycosyl hydrolase 30 family	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_583662_0	59374.Fisuc_0389	2.081e-80	286.0	COG3507@1|root,COG5297@1|root,COG3507@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	-	-	3.2.1.8	ko:K01181,ko:K09955	-	-	-	-	ko00000,ko01000	-	-	-	ArabFuran-catal,CBM_4_9,CBM_6,DUF1080,DUF4091,Dockerin_1,F5_F8_type_C,Glyco_hydro_10,Glyco_hydro_127,Glyco_hydro_43,Laminin_G_3,RicinB_lectin_2
SHD3_k127_585655_0	1499967.BAYZ01000059_gene4772	0.0	1031.0	COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.12.1.3	ko:K18331	-	-	-	-	ko00000,ko01000	-	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB
SHD3_k127_585655_3	880073.Calab_1429	1.338e-50	184.0	COG1905@1|root,COG1905@2|Bacteria,2NPSB@2323|unclassified Bacteria	2|Bacteria	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.12.1.4,1.6.5.3	ko:K00334,ko:K17999	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
SHD3_k127_585655_2	880073.Calab_1430	3.09e-51	189.0	COG2344@1|root,COG2344@2|Bacteria,2NPI1@2323|unclassified Bacteria	2|Bacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
SHD3_k127_585655_1	1168289.AJKI01000015_gene2172	1.529e-88	311.0	COG2730@1|root,COG2730@2|Bacteria,4NNCY@976|Bacteroidetes,2G2A7@200643|Bacteroidia,3XKJR@558415|Marinilabiliaceae	976|Bacteroidetes	G	Cellulase (glycosyl hydrolase family 5)	-	-	3.2.1.78	ko:K01218	ko00051,ko02024,map00051,map02024	-	R01332	RC00467	ko00000,ko00001,ko01000	-	GH26	-	Cellulase
SHD3_k127_588957_6	1195236.CTER_5225	2.394e-28	133.0	COG3533@1|root,COG3533@2|Bacteria,1VWG6@1239|Firmicutes,250SM@186801|Clostridia,3WPCF@541000|Ruminococcaceae	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_588957_3	479432.Sros_2447	7.025e-74	269.0	COG3507@1|root,COG3507@2|Bacteria,2I911@201174|Actinobacteria,4EGG5@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
SHD3_k127_588957_0	1254432.SCE1572_18965	1.492e-238	766.0	COG2844@1|root,COG2844@2|Bacteria,1MV54@1224|Proteobacteria,42MN5@68525|delta/epsilon subdivisions,2WINN@28221|Deltaproteobacteria,2YU3A@29|Myxococcales	28221|Deltaproteobacteria	H	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	-	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,DUF294,GlnD_UR_UTase,GlnE,HD,NTP_transf_2
SHD3_k127_588957_7	1192034.CAP_5328	4.059e-26	115.0	2EHJS@1|root,33BBN@2|Bacteria,1NP80@1224|Proteobacteria,439MQ@68525|delta/epsilon subdivisions,2X4YU@28221|Deltaproteobacteria,2YZV4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_588957_4	1254432.SCE1572_25715	7.711e-65	233.0	COG5549@1|root,COG5549@2|Bacteria,1PBXR@1224|Proteobacteria,43864@68525|delta/epsilon subdivisions,2X0VV@28221|Deltaproteobacteria,2YVXH@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SHD3_k127_588957_5	1158762.KB898043_gene1098	2.691e-49	196.0	COG0763@1|root,COG0763@2|Bacteria,1MVBI@1224|Proteobacteria,1RNS1@1236|Gammaproteobacteria,1WY1X@135613|Chromatiales	135613|Chromatiales	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxB	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
SHD3_k127_588957_9	1117647.M5M_18815	5.723e-16	92.0	COG1807@1|root,COG1807@2|Bacteria,1P6JE@1224|Proteobacteria,1RPPS@1236|Gammaproteobacteria,1J7CA@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	M	Related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PMT_2
SHD3_k127_588957_2	1192034.CAP_5324	8.977e-119	389.0	COG0502@1|root,COG0502@2|Bacteria,1MVFF@1224|Proteobacteria,42PK8@68525|delta/epsilon subdivisions,2X5GR@28221|Deltaproteobacteria,2YV7E@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
SHD3_k127_588957_1	1192034.CAP_5323	2.921e-132	430.0	COG2805@1|root,COG2805@2|Bacteria,1MU3J@1224|Proteobacteria,42M7F@68525|delta/epsilon subdivisions,2WJ4Z@28221|Deltaproteobacteria,2YXJE@29|Myxococcales	28221|Deltaproteobacteria	NU	twitching motility protein	pilT1	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
SHD3_k127_588957_10	1196029.ALIM01000032_gene1463	0.0002462	50.0	2EG8N@1|root,33A0G@2|Bacteria,1VP0T@1239|Firmicutes,4IRMF@91061|Bacilli,1ZRVJ@1386|Bacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_601894_2	448385.sce7567	2.372e-36	151.0	COG5662@1|root,COG5662@2|Bacteria,1PC36@1224|Proteobacteria,4387X@68525|delta/epsilon subdivisions,2X3HP@28221|Deltaproteobacteria,2YW5D@29|Myxococcales	28221|Deltaproteobacteria	K	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
SHD3_k127_601894_0	1254432.SCE1572_43770	4.515e-85	287.0	COG1595@1|root,COG1595@2|Bacteria,1PEJM@1224|Proteobacteria,4380A@68525|delta/epsilon subdivisions,2X3AB@28221|Deltaproteobacteria,2YV3Y@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	rpoE	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_601894_1	448385.sce7563	1.639e-66	246.0	COG0265@1|root,COG1005@1|root,COG0265@2|Bacteria,COG1005@2|Bacteria,1MU2R@1224|Proteobacteria,42MMX@68525|delta/epsilon subdivisions,2WIX8@28221|Deltaproteobacteria,2YYND@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh,PDZ_2
SHD3_k127_606558_7	234267.Acid_1334	8.061e-48	182.0	COG0235@1|root,COG0235@2|Bacteria,3Y66P@57723|Acidobacteria	57723|Acidobacteria	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
SHD3_k127_606558_14	82654.Pse7367_0729	0.0003359	49.0	COG4319@1|root,COG4319@2|Bacteria,1G6QY@1117|Cyanobacteria,1HBIC@1150|Oscillatoriales	1117|Cyanobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
SHD3_k127_606558_4	1220534.B655_1297	6.482e-55	208.0	arCOG12322@1|root,arCOG12322@2157|Archaea	2157|Archaea	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_606558_5	383372.Rcas_0048	1.117e-53	203.0	COG0042@1|root,COG0042@2|Bacteria,2G6XB@200795|Chloroflexi,374WR@32061|Chloroflexia	32061|Chloroflexia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
SHD3_k127_606558_0	886293.Sinac_5754	0.0	1012.0	COG0466@1|root,COG0466@2|Bacteria	2|Bacteria	O	ATP-dependent peptidase activity	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
SHD3_k127_606558_2	448385.sce7661	3.425e-70	254.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42QEI@68525|delta/epsilon subdivisions	1224|Proteobacteria	KLT	Serine Threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_606558_10	1278073.MYSTI_05768	1.638e-28	132.0	2DVPF@1|root,33WNU@2|Bacteria	2|Bacteria	S	Putative peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Metallopep
SHD3_k127_606558_8	452637.Oter_1833	1.322e-44	166.0	COG3981@1|root,COG3981@2|Bacteria,46WUY@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
SHD3_k127_606558_1	1192034.CAP_4252	7.429e-81	285.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_606558_3	96561.Dole_2360	2.977e-61	237.0	COG3356@1|root,COG3356@2|Bacteria,1QW1Q@1224|Proteobacteria,43BRP@68525|delta/epsilon subdivisions,2X72J@28221|Deltaproteobacteria,2MMRW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
SHD3_k127_606558_13	448385.sce3792	3.967e-05	55.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce3792|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_606558_6	1242864.D187_009241	8.388e-53	205.0	COG0457@1|root,COG0515@1|root,COG0457@2|Bacteria,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42VSC@68525|delta/epsilon subdivisions,2WVIT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	T	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_606558_9	1144275.COCOR_00244	6.931e-32	136.0	COG1595@1|root,COG1595@2|Bacteria,1Q2GH@1224|Proteobacteria,43830@68525|delta/epsilon subdivisions,2X0DG@28221|Deltaproteobacteria,2YVH2@29|Myxococcales	28221|Deltaproteobacteria	K	DNA-binding regulatory protein	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_606558_11	1254432.SCE1572_09715	3.584e-22	100.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_616378_0	1192034.CAP_2127	3.648e-48	193.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_616378_4	404380.Gbem_3242	6.569e-08	55.0	COG3064@1|root,COG3064@2|Bacteria,1R4YM@1224|Proteobacteria	1224|Proteobacteria	M	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_616378_2	1121396.KB893120_gene3067	2.761e-36	146.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,42YNG@68525|delta/epsilon subdivisions,2WU6B@28221|Deltaproteobacteria,2MN61@213118|Desulfobacterales	28221|Deltaproteobacteria	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_616378_1	1242864.D187_000792	6.527e-43	173.0	COG0265@1|root,COG1266@1|root,COG0265@2|Bacteria,COG1266@2|Bacteria,1NMQX@1224|Proteobacteria,4334M@68525|delta/epsilon subdivisions,2WY91@28221|Deltaproteobacteria	28221|Deltaproteobacteria	O	CAAX amino terminal protease family	-	-	-	-	-	-	-	-	-	-	-	-	Abi,PDZ_2
SHD3_k127_616378_5	59374.Fisuc_0362	1.355e-06	54.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	yjeA	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	DUF3298,DUF4163,Glyco_hydro_11,Polysacc_deac_1
SHD3_k127_616378_3	1278073.MYSTI_02644	6.223e-26	124.0	COG1506@1|root,COG1506@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PA14
SHD3_k127_616726_6	1192034.CAP_2724	1.066e-29	122.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,42MKX@68525|delta/epsilon subdivisions,2WKXU@28221|Deltaproteobacteria,2YV73@29|Myxococcales	28221|Deltaproteobacteria	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
SHD3_k127_616726_3	1192034.CAP_2719	6.356e-39	149.0	2AIXD@1|root,319F1@2|Bacteria,1Q2IM@1224|Proteobacteria,4385A@68525|delta/epsilon subdivisions,2X3FB@28221|Deltaproteobacteria,2YVU7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_616726_5	448385.sce0648	1.345e-36	149.0	COG2885@1|root,COG2885@2|Bacteria,1QAG8@1224|Proteobacteria,4352E@68525|delta/epsilon subdivisions,2WZDB@28221|Deltaproteobacteria,2Z1W3@29|Myxococcales	28221|Deltaproteobacteria	M	Belongs to the ompA family	-	-	-	ko:K03640	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	OmpA
SHD3_k127_616726_1	1254432.SCE1572_04390	4.213e-55	201.0	COG0811@1|root,COG0811@2|Bacteria,1NCWW@1224|Proteobacteria,42PKF@68525|delta/epsilon subdivisions,2X1X5@28221|Deltaproteobacteria,2Z23Q@29|Myxococcales	28221|Deltaproteobacteria	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03562	ko01120,map01120	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	MotA_ExbB
SHD3_k127_616726_2	1192034.CAP_4481	6.142e-47	175.0	COG0848@1|root,COG0848@2|Bacteria,1MZ6M@1224|Proteobacteria,42U00@68525|delta/epsilon subdivisions,2WQD4@28221|Deltaproteobacteria,2YVFC@29|Myxococcales	28221|Deltaproteobacteria	U	Biopolymer transport protein ExbD/TolR	tolR	-	-	ko:K03560	-	-	-	-	ko00000,ko02000	1.A.30.2.2	-	-	ExbD
SHD3_k127_616726_0	1192034.CAP_4483	8.213e-94	325.0	COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,42PHP@68525|delta/epsilon subdivisions,2WIXN@28221|Deltaproteobacteria,2YVNE@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in the TonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40,TolB_N
SHD3_k127_617524_1	1254432.SCE1572_14350	1.054e-77	267.0	COG0004@1|root,COG0004@2|Bacteria,1NR9F@1224|Proteobacteria,42MFT@68525|delta/epsilon subdivisions,2WIXC@28221|Deltaproteobacteria,2Z2XY@29|Myxococcales	28221|Deltaproteobacteria	P	Ammonium Transporter Family	amtB	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SHD3_k127_617524_0	483219.LILAB_14210	2.894e-135	448.0	28WH1@1|root,2ZIH5@2|Bacteria,1N53T@1224|Proteobacteria,43CXN@68525|delta/epsilon subdivisions,2X85S@28221|Deltaproteobacteria,2YX1G@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_617524_3	450851.PHZ_c2654	3.839e-73	251.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,2U5BS@28211|Alphaproteobacteria,2KGM0@204458|Caulobacterales	204458|Caulobacterales	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SHD3_k127_617524_4	518766.Rmar_1931	6.513e-59	228.0	COG0613@1|root,COG0613@2|Bacteria,4NX7H@976|Bacteroidetes,1FJ9Y@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	DNA polymerase alpha chain like domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
SHD3_k127_617524_7	1192034.CAP_1515	1.975e-30	135.0	COG2304@1|root,COG2304@2|Bacteria	2|Bacteria	IU	oxidoreductase activity	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA,VWA_2
SHD3_k127_617524_10	913865.DOT_1025	6.948e-06	58.0	29JY6@1|root,306VF@2|Bacteria,1UTWY@1239|Firmicutes,254PX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_617524_6	448385.sce4606	3.897e-36	149.0	COG3509@1|root,COG3509@2|Bacteria,1R9H9@1224|Proteobacteria	1224|Proteobacteria	Q	COG3509 Poly(3-hydroxybutyrate) depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Abhydrolase_2,Esterase_phd
SHD3_k127_617524_11	1301098.PKB_1750	0.0008371	48.0	2C0Z5@1|root,30A8M@2|Bacteria,1QT69@1224|Proteobacteria,1STUY@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_617524_5	378806.STAUR_7978	7.362e-53	196.0	2CAZG@1|root,30VUZ@2|Bacteria,1PPP8@1224|Proteobacteria,435CM@68525|delta/epsilon subdivisions,2WZQ7@28221|Deltaproteobacteria,2Z2I0@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4276)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4276
SHD3_k127_617524_2	768671.ThimaDRAFT_4646	4.539e-77	267.0	COG4637@1|root,COG4637@2|Bacteria,1ND40@1224|Proteobacteria,1RPX7@1236|Gammaproteobacteria,1X0JH@135613|Chromatiales	135613|Chromatiales	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
SHD3_k127_619098_5	1192034.CAP_6319	8.725e-77	268.0	COG0515@1|root,COG0515@2|Bacteria	1192034.CAP_6319|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_619098_8	1254432.SCE1572_33835	1.151e-26	123.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SHD3_k127_619098_9	448385.sce4333	3.256e-12	80.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3,NHL
SHD3_k127_619098_11	1206732.BAGD01000259_gene5871	2.262e-08	68.0	COG3863@1|root,COG5479@1|root,COG3863@2|Bacteria,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4FYNN@85025|Nocardiaceae	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
SHD3_k127_619098_6	1144275.COCOR_04821	1.986e-30	137.0	COG4713@1|root,COG4713@2|Bacteria,1RB29@1224|Proteobacteria,432DN@68525|delta/epsilon subdivisions,2WYDT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
SHD3_k127_619098_1	404589.Anae109_2365	1.043e-149	515.0	COG0642@1|root,COG0745@1|root,COG0745@2|Bacteria,COG2205@2|Bacteria,1QV0D@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,MEDS,PAS_4,Response_reg,RsbRD_N
SHD3_k127_619098_4	404589.Anae109_2366	3.032e-118	394.0	COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,42QZV@68525|delta/epsilon subdivisions,2WN5Z@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR	-	-	3.1.1.61,3.5.1.44	ko:K03412	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CheB_methylest,Response_reg
SHD3_k127_619098_0	404589.Anae109_2367	2.159e-184	598.0	COG0643@1|root,COG0745@1|root,COG0643@2|Bacteria,COG0745@2|Bacteria,1NSFS@1224|Proteobacteria	1224|Proteobacteria	T	Histidine Phosphotransfer domain	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,HATPase_c,Hpt,Response_reg
SHD3_k127_619098_3	404589.Anae109_2368	2.027e-136	455.0	COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,42MBK@68525|delta/epsilon subdivisions,2WKDV@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	PFAM chemotaxis sensory transducer	mcp40H-17	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,MCPsignal
SHD3_k127_619098_10	1192034.CAP_8812	3.041e-11	70.0	COG0835@1|root,COG0835@2|Bacteria,1PX96@1224|Proteobacteria,434DE@68525|delta/epsilon subdivisions,2WYQJ@28221|Deltaproteobacteria,2Z0DB@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	ko:K03408	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	CheW
SHD3_k127_619098_2	404589.Anae109_2370	9.002e-139	466.0	COG1352@1|root,COG3170@1|root,COG1352@2|Bacteria,COG3170@2|Bacteria,1R6N1@1224|Proteobacteria,42T12@68525|delta/epsilon subdivisions,2WPTY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	NT	Methyltransferase, chemotaxis proteins	-	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N,Response_reg,TPR_16
SHD3_k127_619098_7	1192034.CAP_8814	1.085e-26	114.0	COG0835@1|root,COG0835@2|Bacteria,1Q2HD@1224|Proteobacteria,43841@68525|delta/epsilon subdivisions,2X3DZ@28221|Deltaproteobacteria,2YVMU@29|Myxococcales	28221|Deltaproteobacteria	NT	Two component signalling adaptor domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
SHD3_k127_61926_21	196367.JNFG01000215_gene703	8.187e-15	79.0	COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2VHRA@28216|Betaproteobacteria,1JZXK@119060|Burkholderiaceae	28216|Betaproteobacteria	P	import. Responsible for energy coupling to the transport system	rbsA	-	3.6.3.17	ko:K02056,ko:K10441,ko:K10562	ko02010,map02010	M00212,M00220,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9	-	-	ABC_tran
SHD3_k127_61926_12	391625.PPSIR1_34113	9.962e-90	316.0	COG2200@1|root,COG2204@1|root,COG2200@2|Bacteria,COG2204@2|Bacteria,1MVJY@1224|Proteobacteria,42S4U@68525|delta/epsilon subdivisions,2WTJ9@28221|Deltaproteobacteria,2Z1P1@29|Myxococcales	28221|Deltaproteobacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL
SHD3_k127_61926_18	1121403.AUCV01000001_gene772	2.836e-24	111.0	COG3809@1|root,COG3809@2|Bacteria,1PZB0@1224|Proteobacteria,433GD@68525|delta/epsilon subdivisions,2WXX5@28221|Deltaproteobacteria,2MP8T@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Transcription factor zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-TFIIB
SHD3_k127_61926_4	1283300.ATXB01000001_gene664	3.241e-162	521.0	COG0366@1|root,COG0366@2|Bacteria,1MWBZ@1224|Proteobacteria,1RYKS@1236|Gammaproteobacteria,1XFWC@135618|Methylococcales	135618|Methylococcales	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	hDGE_amylase
SHD3_k127_61926_1	1254432.SCE1572_17995	5.855e-230	730.0	COG1651@1|root,COG1651@2|Bacteria,1RKYF@1224|Proteobacteria,42T64@68525|delta/epsilon subdivisions,2WP82@28221|Deltaproteobacteria,2YU4W@29|Myxococcales	28221|Deltaproteobacteria	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_4
SHD3_k127_61926_2	448385.sce2960	7.557e-203	665.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,4399Y@68525|delta/epsilon subdivisions,2X4HE@28221|Deltaproteobacteria,2YZ0V@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase; unclassified specificity.	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_61926_13	234267.Acid_2161	2.832e-62	237.0	2DV06@1|root,33TAT@2|Bacteria,3Y720@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_61926_6	1192034.CAP_4998	3.12e-137	453.0	COG1640@1|root,COG1640@2|Bacteria,1QTVJ@1224|Proteobacteria,42PZB@68525|delta/epsilon subdivisions,2WK77@28221|Deltaproteobacteria,2YVA7@29|Myxococcales	28221|Deltaproteobacteria	G	4-alpha-glucanotransferase	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
SHD3_k127_61926_22	1038859.AXAU01000001_gene2613	9.652e-13	72.0	2AKTJ@1|root,31BKK@2|Bacteria,1NYB1@1224|Proteobacteria,2UTN8@28211|Alphaproteobacteria,3K4H7@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_61926_0	1254432.SCE1572_42195	2.168e-260	812.0	COG0504@1|root,COG0504@2|Bacteria,1MUIT@1224|Proteobacteria,42MEU@68525|delta/epsilon subdivisions,2WJ0F@28221|Deltaproteobacteria,2YTT7@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_1276	CTP_synth_N,GATase
SHD3_k127_61926_8	1254432.SCE1572_42215	3.44e-113	386.0	COG2027@1|root,COG2027@2|Bacteria,1MW40@1224|Proteobacteria,42UDC@68525|delta/epsilon subdivisions,2X5AW@28221|Deltaproteobacteria,2Z34Y@29|Myxococcales	28221|Deltaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	dacB	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
SHD3_k127_61926_16	1131462.DCF50_p892	8.005e-33	135.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,26732@186807|Peptococcaceae	186801|Clostridia	S	Conserved protein of DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
SHD3_k127_61926_17	448385.sce0315	1.458e-27	124.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2,YjbH
SHD3_k127_61926_7	398767.Glov_3033	7.355e-136	445.0	COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,42YJ3@68525|delta/epsilon subdivisions,2WUQQ@28221|Deltaproteobacteria,43SUN@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
SHD3_k127_61926_3	1123274.KB899409_gene482	4.546e-171	545.0	COG0436@1|root,COG0436@2|Bacteria,2J6H6@203691|Spirochaetes	203691|Spirochaetes	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
SHD3_k127_61926_9	794903.OPIT5_04180	7.011e-112	368.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,3K7F5@414999|Opitutae	414999|Opitutae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
SHD3_k127_61926_10	1254432.SCE1572_50535	9.444e-112	371.0	COG1879@1|root,COG1879@2|Bacteria,1MU95@1224|Proteobacteria	1224|Proteobacteria	G	Periplasmic binding protein LacI transcriptional regulator	alsB	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
SHD3_k127_61926_5	452637.Oter_3321	1.422e-142	467.0	COG1129@1|root,COG1129@2|Bacteria,46UQP@74201|Verrucomicrobia,3K90Q@414999|Opitutae	414999|Opitutae	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
SHD3_k127_61926_11	448385.sce3324	8.354e-109	363.0	COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,42QIH@68525|delta/epsilon subdivisions,2WIR8@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057,ko:K10440	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
SHD3_k127_61926_19	395492.Rleg2_5373	5.874e-22	104.0	28PFH@1|root,2ZC6N@2|Bacteria,1RE9A@1224|Proteobacteria,2US7V@28211|Alphaproteobacteria,4BIHZ@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Domain of unknown function (DUF4272)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4272
SHD3_k127_61926_14	448385.sce5637	4.929e-53	199.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	cpoB	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TolA_bind_tri
SHD3_k127_622122_0	903818.KI912268_gene1007	3.405e-121	394.0	COG1053@1|root,COG1053@2|Bacteria,3Y2MQ@57723|Acidobacteria	57723|Acidobacteria	C	Succinate dehydrogenase or fumarate reductase, flavoprotein subunit	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
SHD3_k127_622122_2	324602.Caur_1880	1.839e-101	339.0	COG0479@1|root,COG0479@2|Bacteria,2GACG@200795|Chloroflexi,3758X@32061|Chloroflexia	32061|Chloroflexia	C	4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
SHD3_k127_622122_3	742767.HMPREF9456_01739	1.24e-98	336.0	COG0045@1|root,COG0045@2|Bacteria,4NFHA@976|Bacteroidetes,2FNFG@200643|Bacteroidia,22XK2@171551|Porphyromonadaceae	976|Bacteroidetes	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
SHD3_k127_622122_1	1382356.JQMP01000003_gene1858	1.901e-102	351.0	COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia	189775|Thermomicrobia	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
SHD3_k127_622888_4	1192034.CAP_8373	1.001e-56	211.0	COG0457@1|root,COG0457@2|Bacteria	1192034.CAP_8373|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_622888_2	448385.sce4237	5.727e-79	268.0	COG4636@1|root,COG4636@2|Bacteria,1Q8YX@1224|Proteobacteria,4344R@68525|delta/epsilon subdivisions,2X57Z@28221|Deltaproteobacteria,2Z08R@29|Myxococcales	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_622888_1	1254432.SCE1572_51935	2.165e-211	664.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,42M1W@68525|delta/epsilon subdivisions,2WK53@28221|Deltaproteobacteria,2YTVW@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
SHD3_k127_622888_5	1283299.AUKG01000002_gene3802	1.216e-38	164.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,4CPUJ@84995|Rubrobacteria	84995|Rubrobacteria	P	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SHD3_k127_622888_6	1297742.A176_07656	8.279e-16	88.0	COG0003@1|root,COG0003@2|Bacteria,1NA7C@1224|Proteobacteria,42V2J@68525|delta/epsilon subdivisions,2WS25@28221|Deltaproteobacteria,2YUZS@29|Myxococcales	28221|Deltaproteobacteria	P	Anion-transporting ATPase	-	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
SHD3_k127_622888_3	1192034.CAP_2185	1.258e-68	263.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	HYR,HtaA,Neocarzinostat
SHD3_k127_633146_1	1192034.CAP_6942	2.042e-89	311.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42MVV@68525|delta/epsilon subdivisions,2X4JB@28221|Deltaproteobacteria,2YZ4I@29|Myxococcales	28221|Deltaproteobacteria	KLT	Family membership	-	-	2.7.11.1	ko:K08884	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_633146_5	448385.sce2054	4.007e-20	102.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce2054|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_633146_0	1192034.CAP_3785	1e-134	439.0	COG0039@1|root,COG0039@2|Bacteria,1MV57@1224|Proteobacteria,42KZJ@68525|delta/epsilon subdivisions,2WJ4U@28221|Deltaproteobacteria,2YVVI@29|Myxococcales	28221|Deltaproteobacteria	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
SHD3_k127_633146_3	368407.Memar_0814	3.219e-63	237.0	COG1108@1|root,arCOG01006@2157|Archaea,2XTNB@28890|Euryarchaeota,2N9BQ@224756|Methanomicrobia	224756|Methanomicrobia	P	ABC 3 transport family	-	-	-	ko:K09816	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	iAF692.Mbar_A0996	ABC-3
SHD3_k127_633146_2	43989.cce_2962	3.728e-70	246.0	COG1121@1|root,COG1121@2|Bacteria,1G2EJ@1117|Cyanobacteria,3KGBQ@43988|Cyanothece	1117|Cyanobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K09817	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ABC_tran
SHD3_k127_633146_4	194439.CT2106	4.335e-56	206.0	COG0803@1|root,COG0803@2|Bacteria,1FEDW@1090|Chlorobi	1090|Chlorobi	P	PFAM periplasmic solute binding protein	-	-	-	ko:K09815	ko02010,map02010	M00242	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.3,3.A.1.15.5	-	-	ZnuA
SHD3_k127_633146_6	1499967.BAYZ01000108_gene2200	6.85e-17	86.0	COG0524@1|root,COG0524@2|Bacteria	2|Bacteria	G	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73	ko:K00852,ko:K00856,ko:K10710,ko:K22026	ko00030,ko00230,ko00240,ko01100,map00030,map00230,map00240,map01100	-	R00185,R00513,R01051,R01131,R01228,R02750,R08124	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
SHD3_k127_635325_8	479433.Caci_6626	1.874e-09	68.0	COG3664@1|root,COG4733@1|root,COG3664@2|Bacteria,COG4733@2|Bacteria,2GK1U@201174|Actinobacteria	201174|Actinobacteria	E	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
SHD3_k127_635325_2	1206731.BAGB01000076_gene6657	1.912e-119	402.0	COG3315@1|root,COG3315@2|Bacteria,2GN89@201174|Actinobacteria,4G3VX@85025|Nocardiaceae	201174|Actinobacteria	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
SHD3_k127_635325_3	448385.sce4649	1.08e-78	278.0	COG2382@1|root,COG2382@2|Bacteria	2|Bacteria	P	enterobactin catabolic process	-	-	-	ko:K07214	-	-	-	-	ko00000	-	-	-	Esterase
SHD3_k127_635325_5	204669.Acid345_2336	7.879e-60	229.0	COG1032@1|root,COG1032@2|Bacteria,3Y7D8@57723|Acidobacteria,2JMKA@204432|Acidobacteriia	204432|Acidobacteriia	C	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
SHD3_k127_635325_7	1254432.SCE1572_04435	1.997e-13	81.0	COG1266@1|root,COG1668@1|root,COG1266@2|Bacteria,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales	28221|Deltaproteobacteria	CP	sodium ABC transporter, permease	-	-	-	ko:K09696	ko02010,ko02020,map02010,map02020	M00253	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.115	-	-	ABC2_membrane_2,Abi
SHD3_k127_635325_1	448385.sce9054	6.746e-130	424.0	COG0568@1|root,COG0568@2|Bacteria,1MVWR@1224|Proteobacteria,42NRM@68525|delta/epsilon subdivisions,2WJ0S@28221|Deltaproteobacteria,2YU1B@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoH	-	-	ko:K03086,ko:K03089	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
SHD3_k127_635325_4	1192034.CAP_7395	1.52e-71	252.0	COG0313@1|root,COG0313@2|Bacteria,1MU0E@1224|Proteobacteria,42P3I@68525|delta/epsilon subdivisions,2WM37@28221|Deltaproteobacteria,2YV9J@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
SHD3_k127_635325_0	1254432.SCE1572_49495	2.912e-229	721.0	COG0541@1|root,COG0541@2|Bacteria,1MVIA@1224|Proteobacteria,42M94@68525|delta/epsilon subdivisions,2WINB@28221|Deltaproteobacteria,2YUHB@29|Myxococcales	28221|Deltaproteobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
SHD3_k127_640475_3	439235.Dalk_0918	1.277e-22	100.0	COG0238@1|root,COG0238@2|Bacteria,1MZ8U@1224|Proteobacteria,42VJQ@68525|delta/epsilon subdivisions,2WR7Z@28221|Deltaproteobacteria,2MKM0@213118|Desulfobacterales	28221|Deltaproteobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
SHD3_k127_640475_2	1254432.SCE1572_40780	5.034e-34	140.0	COG0359@1|root,COG0359@2|Bacteria,1RD0R@1224|Proteobacteria,42SCQ@68525|delta/epsilon subdivisions,2WPZQ@28221|Deltaproteobacteria,2YX0Q@29|Myxococcales	28221|Deltaproteobacteria	J	binds to the 23S rRNA	rplI	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
SHD3_k127_640475_0	448385.sce6941	1.056e-183	588.0	COG0305@1|root,COG0305@2|Bacteria,1MUG9@1224|Proteobacteria,42M7X@68525|delta/epsilon subdivisions,2WJCA@28221|Deltaproteobacteria,2YTXF@29|Myxococcales	28221|Deltaproteobacteria	L	it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
SHD3_k127_640475_1	502025.Hoch_2991	8.043e-62	218.0	COG0583@1|root,COG0583@2|Bacteria,1MVHT@1224|Proteobacteria,42UN5@68525|delta/epsilon subdivisions,2WQU9@28221|Deltaproteobacteria,2YXHW@29|Myxococcales	28221|Deltaproteobacteria	K	Transcriptional regulator	-	-	-	ko:K03717	-	-	-	-	ko00000,ko03000	-	-	-	HTH_1,LysR_substrate
SHD3_k127_641927_1	1089551.KE386572_gene276	2.256e-97	343.0	COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,2TQS3@28211|Alphaproteobacteria,4BRPX@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS,PAS_4,PAS_8,Response_reg
SHD3_k127_641927_2	903818.KI912269_gene401	1.565e-77	268.0	COG1592@1|root,COG1592@2|Bacteria,3Y5YA@57723|Acidobacteria	57723|Acidobacteria	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
SHD3_k127_641927_0	903818.KI912268_gene624	7.809e-103	354.0	COG1251@1|root,COG1592@1|root,COG1251@2|Bacteria,COG1592@2|Bacteria,3Y6PZ@57723|Acidobacteria	57723|Acidobacteria	C	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
SHD3_k127_641927_4	1192034.CAP_6298	5.737e-15	79.0	COG1366@1|root,COG1366@2|Bacteria,1NJJA@1224|Proteobacteria,43B92@68525|delta/epsilon subdivisions,2X6NE@28221|Deltaproteobacteria,2Z1QN@29|Myxococcales	28221|Deltaproteobacteria	T	Belongs to the anti-sigma-factor antagonist family	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
SHD3_k127_641927_3	1254432.SCE1572_07050	5.057e-48	193.0	COG3119@1|root,COG3119@2|Bacteria,1QZST@1224|Proteobacteria,43CMS@68525|delta/epsilon subdivisions,2X7UX@28221|Deltaproteobacteria,2Z29A@29|Myxococcales	28221|Deltaproteobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
SHD3_k127_641927_5	4558.Sb01g045040.1	0.0007856	50.0	28NGJ@1|root,2QV26@2759|Eukaryota,37PB2@33090|Viridiplantae,3G8QC@35493|Streptophyta,3M4NG@4447|Liliopsida,3IB30@38820|Poales	35493|Streptophyta	K	DNA-binding domain in plant proteins such as APETALA2 and EREBPs	-	-	-	ko:K09286	-	-	-	-	ko00000,ko03000	-	-	-	AP2
SHD3_k127_646085_2	448385.sce6854	1.148e-58	230.0	COG3055@1|root,COG3055@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
SHD3_k127_646085_4	1120950.KB892709_gene4049	5.027e-05	53.0	COG1595@1|root,COG1595@2|Bacteria,2GMPC@201174|Actinobacteria,4DRXB@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_646085_1	1254432.SCE1572_14465	2.402e-127	453.0	COG0784@1|root,COG2202@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG5002@2|Bacteria,1NC9X@1224|Proteobacteria,43BJQ@68525|delta/epsilon subdivisions,2X7N6@28221|Deltaproteobacteria,2Z2X1@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
SHD3_k127_646085_5	448385.sce8648	0.0003084	50.0	COG3055@1|root,COG3391@1|root,COG3055@2|Bacteria,COG3391@2|Bacteria,1Q4PQ@1224|Proteobacteria,4347S@68525|delta/epsilon subdivisions,2X34Y@28221|Deltaproteobacteria,2YUAC@29|Myxococcales	28221|Deltaproteobacteria	V	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_4,TSP_3
SHD3_k127_648531_5	448385.sce5290	2.487e-08	66.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce5290|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_648531_7	56110.Oscil6304_1575	2.987e-05	57.0	COG3420@1|root,COG3420@2|Bacteria,1G2FG@1117|Cyanobacteria,1H7WG@1150|Oscillatoriales	1117|Cyanobacteria	P	S-layer homology domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF1565,SLH
SHD3_k127_648531_0	1254432.SCE1572_49580	5.868e-202	644.0	COG0405@1|root,COG0405@2|Bacteria,1MUV6@1224|Proteobacteria,42NY8@68525|delta/epsilon subdivisions,2WJNT@28221|Deltaproteobacteria,2YU0V@29|Myxococcales	28221|Deltaproteobacteria	M	gamma-glutamyltransferase	ggt	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
SHD3_k127_648531_2	1254432.SCE1572_32630	4.818e-101	340.0	COG4798@1|root,COG4798@2|Bacteria,1NNHX@1224|Proteobacteria	1224|Proteobacteria	S	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SHD3_k127_648531_1	1278073.MYSTI_03501	1.408e-141	456.0	COG0685@1|root,COG0685@2|Bacteria,1MUC9@1224|Proteobacteria,42P5X@68525|delta/epsilon subdivisions,2WIQW@28221|Deltaproteobacteria,2YU6V@29|Myxococcales	28221|Deltaproteobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
SHD3_k127_648531_3	546414.Deide_21610	2.046e-29	134.0	COG2202@1|root,COG4251@1|root,COG2202@2|Bacteria,COG4251@2|Bacteria	2|Bacteria	T	photoreceptor activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9
SHD3_k127_67592_2	1192034.CAP_0393	1.323e-84	301.0	COG0426@1|root,COG0515@1|root,COG0426@2|Bacteria,COG0515@2|Bacteria,1N2Y0@1224|Proteobacteria,42QKU@68525|delta/epsilon subdivisions,2WR5B@28221|Deltaproteobacteria,2YUDV@29|Myxococcales	28221|Deltaproteobacteria	C	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
SHD3_k127_67592_0	1192034.CAP_4198	3.647e-167	534.0	COG0577@1|root,COG0577@2|Bacteria,1PBKH@1224|Proteobacteria,42MAR@68525|delta/epsilon subdivisions,2WJEU@28221|Deltaproteobacteria,2YWC8@29|Myxococcales	28221|Deltaproteobacteria	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
SHD3_k127_67592_8	1121448.DGI_2534	3.864e-13	80.0	COG0517@1|root,COG0517@2|Bacteria,1N0EB@1224|Proteobacteria,42W96@68525|delta/epsilon subdivisions,2WP5S@28221|Deltaproteobacteria,2MC10@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM CBS domain containing protein	-	-	-	ko:K07168	-	-	-	-	ko00000	-	-	-	CBS
SHD3_k127_67592_3	1192034.CAP_0942	2.395e-61	239.0	COG1073@1|root,COG1073@2|Bacteria,1QRTY@1224|Proteobacteria,433U7@68525|delta/epsilon subdivisions,2X3GS@28221|Deltaproteobacteria,2YW15@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_67592_1	1254432.SCE1572_00895	1.068e-164	526.0	2DBF7@1|root,2Z8X0@2|Bacteria,1QXU4@1224|Proteobacteria,42YFE@68525|delta/epsilon subdivisions,2WTQD@28221|Deltaproteobacteria,2YUC6@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Chlam_PMP
SHD3_k127_67592_6	448385.sce4841	9.157e-28	118.0	COG0745@1|root,COG0745@2|Bacteria,1R0CU@1224|Proteobacteria,43CVD@68525|delta/epsilon subdivisions,2X83B@28221|Deltaproteobacteria,2Z1S3@29|Myxococcales	28221|Deltaproteobacteria	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
SHD3_k127_67592_9	446462.Amir_1954	0.0006452	52.0	28JV8@1|root,2Z9K7@2|Bacteria,2I533@201174|Actinobacteria,4DZQH@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_67592_5	1192034.CAP_0795	9.415e-33	145.0	COG0515@1|root,COG1572@1|root,COG0515@2|Bacteria,COG1572@2|Bacteria,1PJRR@1224|Proteobacteria	2|Bacteria	KLT	serine threonine protein kinase	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Big_3_3,CARDB,DUF11,GSDH,Glyco_hyd_65N_2,Laminin_G_3,SdrD_B
SHD3_k127_67592_4	1192034.CAP_0399	4.173e-55	218.0	COG5316@1|root,COG5316@2|Bacteria,1NWFX@1224|Proteobacteria,42NSK@68525|delta/epsilon subdivisions,2WMAZ@28221|Deltaproteobacteria,2YUUF@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF4139)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4139
SHD3_k127_67592_7	1156919.QWC_18157	8.06e-21	95.0	COG1089@1|root,COG1089@2|Bacteria,1MUX0@1224|Proteobacteria,2VIBX@28216|Betaproteobacteria,3T2YI@506|Alcaligenaceae	28216|Betaproteobacteria	H	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
SHD3_k127_683944_6	1304883.KI912532_gene2006	7.87e-67	233.0	COG0282@1|root,COG0664@1|root,COG4869@1|root,COG0282@2|Bacteria,COG0664@2|Bacteria,COG4869@2|Bacteria,1MW61@1224|Proteobacteria,2VHRC@28216|Betaproteobacteria,2KXZH@206389|Rhodocyclales	206389|Rhodocyclales	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	-	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase,PTAC,cNMP_binding
SHD3_k127_683944_4	497964.CfE428DRAFT_4312	1.49e-100	336.0	COG1994@1|root,COG1994@2|Bacteria,46VEB@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50,Peptidase_M50B
SHD3_k127_683944_2	404589.Anae109_0080	2.586e-182	582.0	COG2239@1|root,COG2239@2|Bacteria,1MW24@1224|Proteobacteria,42MA7@68525|delta/epsilon subdivisions,2WIPC@28221|Deltaproteobacteria,2YWVA@29|Myxococcales	28221|Deltaproteobacteria	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
SHD3_k127_683944_5	448385.sce7993	2.724e-76	266.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_683944_1	1035308.AQYY01000002_gene233	8.555e-205	653.0	COG1414@1|root,COG1414@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	3.6.4.12	ko:K03655,ko:K10439,ko:K11708	ko02010,ko02030,ko03440,map02010,map02030,map03440	M00212,M00319	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko03400	3.A.1.15,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	AlbA_2,HATPase_c_4,HTH_IclR,IclR,Peripla_BP_4,VCBS
SHD3_k127_683944_8	1254432.SCE1572_10070	1.309e-07	64.0	2AH4I@1|root,317E5@2|Bacteria,1PYQB@1224|Proteobacteria,435HF@68525|delta/epsilon subdivisions,2X99V@28221|Deltaproteobacteria,2Z2T7@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_683944_3	1192034.CAP_6588	1.408e-131	430.0	COG0604@1|root,COG0604@2|Bacteria,1MXUX@1224|Proteobacteria,42UGV@68525|delta/epsilon subdivisions,2WR1G@28221|Deltaproteobacteria,2YUDE@29|Myxococcales	28221|Deltaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
SHD3_k127_683944_0	518766.Rmar_1185	1.025e-220	702.0	COG3250@1|root,COG3250@2|Bacteria,4NESZ@976|Bacteroidetes	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
SHD3_k127_683944_7	448385.sce8402	9.25e-21	104.0	COG4191@1|root,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,43AKM@68525|delta/epsilon subdivisions,2X60K@28221|Deltaproteobacteria,2Z39T@29|Myxococcales	28221|Deltaproteobacteria	T	HAMP domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
SHD3_k127_706229_1	502025.Hoch_2910	1.216e-98	327.0	COG1484@1|root,COG1484@2|Bacteria,1MWQX@1224|Proteobacteria,42NG2@68525|delta/epsilon subdivisions,2WK33@28221|Deltaproteobacteria,2YV8H@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM IstB domain protein ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
SHD3_k127_706229_0	502025.Hoch_2874	6.454e-206	651.0	COG4584@1|root,COG4584@2|Bacteria,1MWIV@1224|Proteobacteria,42QTE@68525|delta/epsilon subdivisions,2WN61@28221|Deltaproteobacteria,2YUPI@29|Myxococcales	28221|Deltaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,rve
SHD3_k127_718433_9	290397.Adeh_2662	1.819e-22	106.0	COG3021@1|root,COG3021@2|Bacteria,1QAG3@1224|Proteobacteria,4352B@68525|delta/epsilon subdivisions,2WZDA@28221|Deltaproteobacteria,2Z1W0@29|Myxococcales	28221|Deltaproteobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
SHD3_k127_718433_2	448385.sce7663	3.551e-166	535.0	COG2723@1|root,COG2723@2|Bacteria,1MWG6@1224|Proteobacteria,42UR5@68525|delta/epsilon subdivisions,2WQET@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
SHD3_k127_718433_1	1192034.CAP_4136	7.419e-175	567.0	COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,42P77@68525|delta/epsilon subdivisions,2WK7E@28221|Deltaproteobacteria,2YY2C@29|Myxococcales	28221|Deltaproteobacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsI	-	2.7.1.202,2.7.3.9	ko:K02768,ko:K08483,ko:K11183	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1,8.A.7	-	-	EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PTS-HPr
SHD3_k127_718433_11	1232410.KI421421_gene3598	6.76e-19	98.0	COG1925@1|root,COG1925@2|Bacteria,1N6RM@1224|Proteobacteria,42V5C@68525|delta/epsilon subdivisions,2WRC4@28221|Deltaproteobacteria,43VGK@69541|Desulfuromonadales	28221|Deltaproteobacteria	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
SHD3_k127_718433_6	1254432.SCE1572_34250	1.551e-92	316.0	COG1660@1|root,COG1660@2|Bacteria,1MVX6@1224|Proteobacteria,42MZM@68525|delta/epsilon subdivisions,2WJG6@28221|Deltaproteobacteria,2YV1E@29|Myxococcales	28221|Deltaproteobacteria	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
SHD3_k127_718433_4	1254432.SCE1572_34255	4.372e-111	370.0	COG1493@1|root,COG1493@2|Bacteria,1NNN5@1224|Proteobacteria,42P9W@68525|delta/epsilon subdivisions,2WK54@28221|Deltaproteobacteria,2YUU0@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
SHD3_k127_718433_12	1121439.dsat_1422	6.303e-16	87.0	COG1762@1|root,COG1762@2|Bacteria,1RD0E@1224|Proteobacteria,42SD2@68525|delta/epsilon subdivisions,2WP7H@28221|Deltaproteobacteria,2MC5C@213115|Desulfovibrionales	28221|Deltaproteobacteria	G	PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2	ptsN	-	-	ko:K02806	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	-	-	-	PTS_EIIA_2
SHD3_k127_718433_10	1254432.SCE1572_34270	1.366e-21	104.0	COG1544@1|root,COG1544@2|Bacteria,1MZHW@1224|Proteobacteria,42SJW@68525|delta/epsilon subdivisions,2WPF7@28221|Deltaproteobacteria,2YVRH@29|Myxococcales	28221|Deltaproteobacteria	J	Sigma 54 modulation protein / S30EA ribosomal protein	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
SHD3_k127_718433_0	1254432.SCE1572_00150	1.47e-217	685.0	COG1508@1|root,COG1508@2|Bacteria,1MW4V@1224|Proteobacteria,42M3C@68525|delta/epsilon subdivisions,2WJ21@28221|Deltaproteobacteria,2YTW6@29|Myxococcales	28221|Deltaproteobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	rpoN	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
SHD3_k127_718433_8	941449.dsx2_0125	7.625e-46	174.0	COG1137@1|root,COG1137@2|Bacteria,1MU8M@1224|Proteobacteria,42M4J@68525|delta/epsilon subdivisions,2WJM8@28221|Deltaproteobacteria,2M8FR@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	PFAM ABC transporter related	lptB	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran,BCA_ABC_TP_C
SHD3_k127_718433_13	633131.TR2A62_2521	2.233e-09	64.0	COG1934@1|root,COG1934@2|Bacteria,1MXGA@1224|Proteobacteria,2U6DD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Protein conserved in bacteria	lptA	-	-	ko:K09774	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	OstA
SHD3_k127_718433_3	1192034.CAP_6802	3.952e-111	390.0	COG0699@1|root,COG0699@2|Bacteria,1NBKR@1224|Proteobacteria,42NDN@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
SHD3_k127_718433_7	1192034.CAP_6813	3.671e-84	296.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_718433_5	448385.sce3638	4.171e-99	346.0	COG1520@1|root,COG1520@2|Bacteria,1Q3BK@1224|Proteobacteria,4392T@68525|delta/epsilon subdivisions,2X48J@28221|Deltaproteobacteria,2YYHQ@29|Myxococcales	28221|Deltaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
SHD3_k127_718545_2	1254432.SCE1572_03675	2.38e-87	290.0	COG1143@1|root,COG1143@2|Bacteria,1MV90@1224|Proteobacteria,42T2H@68525|delta/epsilon subdivisions,2WRSP@28221|Deltaproteobacteria,2Z31G@29|Myxococcales	28221|Deltaproteobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4,Fer4_7
SHD3_k127_718545_0	1254432.SCE1572_03680	1.03e-166	537.0	COG0064@1|root,COG0064@2|Bacteria,1MUKG@1224|Proteobacteria,42M31@68525|delta/epsilon subdivisions,2WJK4@28221|Deltaproteobacteria,2YUCW@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
SHD3_k127_718545_1	1192034.CAP_6088	1.828e-120	397.0	COG0182@1|root,COG0182@2|Bacteria,1MUPM@1224|Proteobacteria,42MJ2@68525|delta/epsilon subdivisions,2WJQB@28221|Deltaproteobacteria,2YUP1@29|Myxococcales	28221|Deltaproteobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0072	IF-2B
SHD3_k127_718545_3	999630.TUZN_1026	5.538e-85	289.0	COG0320@1|root,arCOG00660@2157|Archaea,2XQ5G@28889|Crenarchaeota	28889|Crenarchaeota	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	Radical_SAM
SHD3_k127_718545_5	1192034.CAP_6082	4.125e-14	76.0	COG2979@1|root,COG2979@2|Bacteria	2|Bacteria	T	Protein of unknown function (DUF533)	-	-	-	ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	DUF533,PG_binding_4,TerB,VanW
SHD3_k127_718545_6	448385.sce1572	1.234e-13	73.0	COG2979@1|root,COG2979@2|Bacteria	2|Bacteria	T	Protein of unknown function (DUF533)	-	-	-	ko:K06596	ko02020,ko02025,map02020,map02025	M00507	-	-	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	-	-	-	PG_binding_4,TerB,VanW
SHD3_k127_718545_4	1192034.CAP_6081	2.958e-25	108.0	COG1071@1|root,COG1071@2|Bacteria,1MU5R@1224|Proteobacteria,42NW8@68525|delta/epsilon subdivisions,2WJY1@28221|Deltaproteobacteria,2YV62@29|Myxococcales	28221|Deltaproteobacteria	C	Dehydrogenase E1 component	bkdA	-	1.2.4.1,1.2.4.4	ko:K00161,ko:K00166	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00036,M00307	R00014,R00209,R01699,R03270,R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00004,RC00027,RC00627,RC02742,RC02743,RC02744,RC02882,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
SHD3_k127_726612_2	448385.sce5953	3.281e-116	387.0	COG0003@1|root,COG0003@2|Bacteria,1PMWP@1224|Proteobacteria,42RUR@68525|delta/epsilon subdivisions,2WNEE@28221|Deltaproteobacteria,2YUU4@29|Myxococcales	28221|Deltaproteobacteria	D	AAA domain	agmR	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
SHD3_k127_726612_1	1254432.SCE1572_35420	9.745e-153	494.0	COG1160@1|root,COG1160@2|Bacteria,1MU9S@1224|Proteobacteria,42M3N@68525|delta/epsilon subdivisions,2WISS@28221|Deltaproteobacteria,2YU6J@29|Myxococcales	28221|Deltaproteobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
SHD3_k127_726612_3	1254432.SCE1572_35415	5.712e-78	273.0	COG1159@1|root,COG1159@2|Bacteria,1MUKT@1224|Proteobacteria,42MUR@68525|delta/epsilon subdivisions,2WJC8@28221|Deltaproteobacteria,2YYQ7@29|Myxococcales	28221|Deltaproteobacteria	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
SHD3_k127_726612_0	1254432.SCE1572_35410	7.586e-172	571.0	COG1807@1|root,COG1807@2|Bacteria,1P6BI@1224|Proteobacteria,433Q7@68525|delta/epsilon subdivisions,2WXUY@28221|Deltaproteobacteria,2Z13P@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_726612_4	1254432.SCE1572_35405	1.458e-46	170.0	COG3215@1|root,COG3215@2|Bacteria,1QASH@1224|Proteobacteria,4359S@68525|delta/epsilon subdivisions,2X978@28221|Deltaproteobacteria,2Z2CF@29|Myxococcales	28221|Deltaproteobacteria	NU	PilZ domain	-	-	-	-	-	-	-	-	-	-	-	-	PilZ
SHD3_k127_73150_0	1254432.SCE1572_48915	1.618e-272	866.0	COG1305@1|root,COG1305@2|Bacteria	2|Bacteria	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3857,DUF3858,LRR_5,Transglut_core
SHD3_k127_73150_2	1121403.AUCV01000032_gene2870	8.598e-44	167.0	COG0778@1|root,COG0778@2|Bacteria,1PDTZ@1224|Proteobacteria,42SQ3@68525|delta/epsilon subdivisions,2WPC5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SHD3_k127_73150_1	1449346.JQMO01000003_gene6329	1.222e-135	451.0	COG1470@1|root,COG1470@2|Bacteria,2I2YC@201174|Actinobacteria,2M64B@2063|Kitasatospora	201174|Actinobacteria	S	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase_2,NPCBM,NPCBM_assoc
SHD3_k127_734510_1	290317.Cpha266_0907	4.252e-55	196.0	COG1661@1|root,COG1661@2|Bacteria,1FF1P@1090|Chlorobi	1090|Chlorobi	S	Domain of unknown function (DUF296)	-	-	-	-	-	-	-	-	-	-	-	-	DUF296
SHD3_k127_734510_4	1282362.AEAC466_14110	0.0009538	45.0	COG3152@1|root,COG3152@2|Bacteria,1MZJ4@1224|Proteobacteria,2UG35@28211|Alphaproteobacteria,2KJTU@204458|Caulobacterales	28211|Alphaproteobacteria	S	Protein of unknown function (DUF805)	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
SHD3_k127_734510_0	1123371.ATXH01000040_gene1172	2.605e-100	344.0	2AM9X@1|root,31C4U@2|Bacteria,2GIDP@200940|Thermodesulfobacteria	200940|Thermodesulfobacteria	S	Hypothetical glycosyl hydrolase family 15	-	-	-	-	-	-	-	-	-	-	-	-	GHL15
SHD3_k127_734510_3	395495.Lcho_1379	4.965e-26	123.0	2EU61@1|root,33MNM@2|Bacteria,1NV9A@1224|Proteobacteria	1224|Proteobacteria	S	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_734510_2	631362.Thi970DRAFT_01668	2.541e-28	118.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pyrroloquinoline quinone biosynthesis protein E	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SHD3_k127_748331_6	391625.PPSIR1_18632	1.632e-54	204.0	COG5297@1|root,COG5297@2|Bacteria,1NDMY@1224|Proteobacteria,4333K@68525|delta/epsilon subdivisions,2WXH7@28221|Deltaproteobacteria,2YXQH@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 9	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_4_9,CelD_N,Glyco_hydro_9
SHD3_k127_748331_7	448385.sce5453	1.641e-48	181.0	COG1595@1|root,COG1595@2|Bacteria,1QRBA@1224|Proteobacteria,43DX0@68525|delta/epsilon subdivisions,2WZ3I@28221|Deltaproteobacteria,2Z194@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_748331_5	1254432.SCE1572_38360	1.589e-58	218.0	COG1729@1|root,COG3712@1|root,COG1729@2|Bacteria,COG3712@2|Bacteria	2|Bacteria	PT	iron ion homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	FecR,TPR_16,TPR_6,WG_beta_rep
SHD3_k127_748331_2	1210884.HG799462_gene8794	9.82e-122	428.0	COG4191@1|root,COG4191@2|Bacteria,2J2PC@203682|Planctomycetes	203682|Planctomycetes	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SHD3_k127_748331_4	518766.Rmar_1114	2.993e-67	236.0	COG0179@1|root,COG0179@2|Bacteria,4NFMZ@976|Bacteroidetes,1FJ8W@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
SHD3_k127_748331_0	518766.Rmar_0127	2.402e-182	580.0	COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,1FIQU@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	H	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
SHD3_k127_748331_8	448385.sce6468	5.08e-39	152.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
SHD3_k127_748331_1	1254432.SCE1572_13385	3.847e-126	411.0	COG3509@1|root,COG3509@2|Bacteria	2|Bacteria	Q	xylan catabolic process	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	CBM_2,Esterase_phd,Peptidase_S9,RicinB_lectin_2,Ricin_B_lectin
SHD3_k127_748331_11	56107.Cylst_4011	2.887e-16	88.0	COG4675@1|root,COG4675@2|Bacteria,1G8V2@1117|Cyanobacteria	1117|Cyanobacteria	S	tail collar domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
SHD3_k127_759468_6	77586.LPERR01G25810.2	4.516e-07	59.0	COG0241@1|root,KOG1037@1|root,KOG1037@2759|Eukaryota,KOG2134@2759|Eukaryota,37P8G@33090|Viridiplantae,3G8Z7@35493|Streptophyta,3KVVC@4447|Liliopsida,3IAKE@38820|Poales	35493|Streptophyta	KLO	Polynucleotide kinase 3 phosphatase	-	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0009117,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010638,GO:0010835,GO:0010836,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0019205,GO:0019219,GO:0019222,GO:0019637,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031400,GO:0031974,GO:0031981,GO:0032204,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032269,GO:0033043,GO:0033044,GO:0033554,GO:0034641,GO:0042578,GO:0042769,GO:0043085,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045935,GO:0046403,GO:0046404,GO:0046483,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051248,GO:0051338,GO:0051347,GO:0051606,GO:0051716,GO:0051731,GO:0051733,GO:0051734,GO:0051972,GO:0051973,GO:0055086,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0098501,GO:0098502,GO:0098503,GO:0098504,GO:0098506,GO:0098518,GO:1901360,GO:1901363,GO:1904353,GO:1904355,GO:1904356,GO:1904358,GO:2000112,GO:2000278,GO:2000573,GO:2001252	2.7.1.78,3.1.3.32	ko:K08073	-	-	-	-	ko00000,ko01000,ko01009,ko03400	-	-	-	PNK3P,zf-PARP
SHD3_k127_759468_4	595494.Tola_0954	4.001e-30	137.0	COG1361@1|root,COG1361@2|Bacteria,1MUQC@1224|Proteobacteria,1RYHS@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	PFAM Peptidase M11 gametolysin	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM_assoc,Peptidase_M11
SHD3_k127_759468_1	290397.Adeh_3389	1.607e-174	570.0	COG0123@1|root,COG0123@2|Bacteria,1MU7P@1224|Proteobacteria,42V54@68525|delta/epsilon subdivisions,2WSDI@28221|Deltaproteobacteria,2YWJM@29|Myxococcales	28221|Deltaproteobacteria	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
SHD3_k127_759468_5	1079986.JH164839_gene4408	1.248e-13	84.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_759468_3	448385.sce7901	2.918e-57	206.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigX	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_759468_0	1254432.SCE1572_45375	1.307e-185	603.0	COG2304@1|root,COG3712@1|root,COG2304@2|Bacteria,COG3712@2|Bacteria,1QRQ1@1224|Proteobacteria,4341K@68525|delta/epsilon subdivisions,2X4NI@28221|Deltaproteobacteria,2YZAV@29|Myxococcales	28221|Deltaproteobacteria	PT	Vault protein inter-alpha-trypsin domain	-	-	-	-	-	-	-	-	-	-	-	-	FecR,VIT,VWA_3
SHD3_k127_76450_1	1121904.ARBP01000062_gene1612	8.058e-22	111.0	COG2730@1|root,COG4935@1|root,COG2730@2|Bacteria,COG4935@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	CHU_C,Cellulase,Inhibitor_I69,Peptidase_C10,SprB
SHD3_k127_76450_0	448385.sce5860	4.132e-25	112.0	COG1595@1|root,COG1595@2|Bacteria,1R7KF@1224|Proteobacteria,4385W@68525|delta/epsilon subdivisions,2X9YP@28221|Deltaproteobacteria,2YVWM@29|Myxococcales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_76450_2	911239.CF149_20336	1.095e-07	64.0	COG3712@1|root,COG3712@2|Bacteria,1RGU3@1224|Proteobacteria,1S996@1236|Gammaproteobacteria	1236|Gammaproteobacteria	PT	peptide ABC transporter substrate-binding protein	-	-	-	ko:K07165	-	-	-	-	ko00000	-	-	-	DUF4880,DUF4974,FecR
SHD3_k127_77128_7	1278073.MYSTI_00081	8.032e-19	94.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,42PZ5@68525|delta/epsilon subdivisions,2WM5Q@28221|Deltaproteobacteria,2YX39@29|Myxococcales	28221|Deltaproteobacteria	T	PAS fold	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_8,PAS_9,Response_reg
SHD3_k127_77128_0	1254432.SCE1572_23155	1.121e-171	555.0	COG1807@1|root,COG1807@2|Bacteria,1QX93@1224|Proteobacteria,43C25@68525|delta/epsilon subdivisions,2X7CQ@28221|Deltaproteobacteria,2YUUE@29|Myxococcales	28221|Deltaproteobacteria	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
SHD3_k127_77128_4	1192034.CAP_7108	3.176e-81	281.0	2A4RR@1|root,30TD5@2|Bacteria,1PD62@1224|Proteobacteria,435EI@68525|delta/epsilon subdivisions,2WZS8@28221|Deltaproteobacteria,2Z2MR@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_77128_2	448385.sce3691	4.833e-132	446.0	COG0451@1|root,COG0451@2|Bacteria,1R4Q0@1224|Proteobacteria	1224|Proteobacteria	M	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SHD3_k127_77128_5	1254432.SCE1572_22540	1.035e-79	276.0	COG1208@1|root,COG1208@2|Bacteria,1RDSE@1224|Proteobacteria	1224|Proteobacteria	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
SHD3_k127_77128_11	1282361.ABAC402_03260	2.772e-06	60.0	COG0457@1|root,COG0457@2|Bacteria,1Q4FC@1224|Proteobacteria,2UDXE@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C
SHD3_k127_77128_12	656024.FsymDg_1056	6.452e-05	55.0	COG1807@1|root,COG1807@2|Bacteria,2IME4@201174|Actinobacteria,4EVSG@85013|Frankiales	201174|Actinobacteria	M	Predicted membrane protein (DUF2142)	-	-	-	ko:K17414	-	-	-	-	br01610,ko00000,ko03011	-	-	-	DUF2142,PMT_2
SHD3_k127_77128_3	926569.ANT_06290	7.478e-123	401.0	COG0451@1|root,COG0451@2|Bacteria,2G7M6@200795|Chloroflexi	200795|Chloroflexi	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
SHD3_k127_77128_1	335543.Sfum_0151	3.153e-154	505.0	COG0500@1|root,COG1216@1|root,COG1216@2|Bacteria,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31,NTP_transf_5
SHD3_k127_77128_9	316274.Haur_3822	3.168e-11	72.0	COG0500@1|root,COG2226@2|Bacteria,2G9CY@200795|Chloroflexi,375EP@32061|Chloroflexia	32061|Chloroflexia	Q	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
SHD3_k127_77128_6	1435356.Y013_03985	1.491e-45	190.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4FU49@85025|Nocardiaceae	201174|Actinobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
SHD3_k127_77128_10	1365176.N186_00425	1.232e-06	58.0	arCOG03743@1|root,arCOG03743@2157|Archaea,2XS5J@28889|Crenarchaeota	28889|Crenarchaeota	O	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
SHD3_k127_77128_8	1144275.COCOR_02469	6.766e-14	78.0	2ANHZ@1|root,31DGT@2|Bacteria,1QARG@1224|Proteobacteria,43598@68525|delta/epsilon subdivisions,2WZKE@28221|Deltaproteobacteria,2Z2B4@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_771803_19	428125.CLOLEP_01942	0.0002856	53.0	28HDP@1|root,2Z7Q8@2|Bacteria,1V01A@1239|Firmicutes,24BY7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_771803_4	632335.Calkr_2478	1.795e-132	432.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,24BGZ@186801|Clostridia,42JAJ@68295|Thermoanaerobacterales	186801|Clostridia	C	PFAM aldo keto reductase	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
SHD3_k127_771803_10	1254432.SCE1572_20885	5.711e-53	202.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	hrpL	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
SHD3_k127_771803_0	1278073.MYSTI_00984	6.432e-210	663.0	COG0477@1|root,COG0477@2|Bacteria,1RGPN@1224|Proteobacteria,43BMI@68525|delta/epsilon subdivisions,2X6ZQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	drug resistance transporter, EmrB QacA subfamily	-	-	-	ko:K03446	-	M00701	-	-	ko00000,ko00002,ko02000	2.A.1.3	-	-	MFS_1
SHD3_k127_771803_6	1278073.MYSTI_00983	3.171e-121	406.0	COG1566@1|root,COG1566@2|Bacteria,1MU7I@1224|Proteobacteria,42S77@68525|delta/epsilon subdivisions,2X5PF@28221|Deltaproteobacteria,2YXJB@29|Myxococcales	28221|Deltaproteobacteria	V	Biotin-lipoyl like	-	-	-	ko:K03543	-	M00701	-	-	ko00000,ko00002,ko02000	8.A.1.1	-	-	Biotin_lipoyl_2,HlyD_D23
SHD3_k127_771803_12	246197.MXAN_0943	5.287e-35	139.0	COG1846@1|root,COG1846@2|Bacteria,1N1RV@1224|Proteobacteria,42WMS@68525|delta/epsilon subdivisions,2WR99@28221|Deltaproteobacteria,2Z2BS@29|Myxococcales	28221|Deltaproteobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
SHD3_k127_771803_5	65393.PCC7424_2861	9.324e-125	407.0	COG0304@1|root,COG0740@1|root,COG0304@2|Bacteria,COG0740@2|Bacteria,1GM56@1117|Cyanobacteria,3KJCF@43988|Cyanothece	1117|Cyanobacteria	IOQU	Serine dehydrogenase proteinase	-	-	-	-	-	-	-	-	-	-	-	-	SDH_sah
SHD3_k127_771803_13	1121403.AUCV01000018_gene3180	1.202e-26	121.0	2DWP7@1|root,3419S@2|Bacteria,1NXHT@1224|Proteobacteria,430NG@68525|delta/epsilon subdivisions,2WVKS@28221|Deltaproteobacteria,2MNQW@213118|Desulfobacterales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_771803_2	1254432.SCE1572_12230	5.744e-156	528.0	COG1073@1|root,COG1073@2|Bacteria,1QRTY@1224|Proteobacteria,433U7@68525|delta/epsilon subdivisions,2X3GS@28221|Deltaproteobacteria,2YW15@29|Myxococcales	28221|Deltaproteobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_771803_20	103733.JNYO01000012_gene2739	0.0006163	49.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4E0FJ@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07665	ko02020,map02020	M00452,M00745	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
SHD3_k127_771803_11	391625.PPSIR1_41879	5.822e-49	199.0	COG0790@1|root,COG0790@2|Bacteria,1MWPA@1224|Proteobacteria,42M5H@68525|delta/epsilon subdivisions	1224|Proteobacteria	S	FOG TPR repeat SEL1 subfamily	hcpD	GO:0003674,GO:0003824,GO:0008800,GO:0016787,GO:0016810,GO:0016812	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_8
SHD3_k127_771803_15	592026.GCWU0000282_001949	1.909e-16	93.0	28K5P@1|root,2Z9U8@2|Bacteria,1UY1H@1239|Firmicutes,24D42@186801|Clostridia	186801|Clostridia	S	HEAT repeats	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
SHD3_k127_771803_16	1254432.SCE1572_18145	1.866e-05	57.0	COG0515@1|root,COG0515@2|Bacteria	1254432.SCE1572_18145|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_771803_17	483219.LILAB_11620	3.251e-05	57.0	COG0745@1|root,COG0745@2|Bacteria	483219.LILAB_11620|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_771803_3	1408422.JHYF01000001_gene2935	2.867e-143	469.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,36EE0@31979|Clostridiaceae	186801|Clostridia	F	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
SHD3_k127_771803_7	1121920.AUAU01000002_gene2003	8.395e-100	339.0	COG0280@1|root,COG0280@2|Bacteria,3Y6AD@57723|Acidobacteria	57723|Acidobacteria	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
SHD3_k127_771803_18	880073.Calab_2512	0.0001883	52.0	COG0720@1|root,COG0720@2|Bacteria,2NPY7@2323|unclassified Bacteria	2|Bacteria	H	6-pyruvoyl tetrahydropterin synthase	queD	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
SHD3_k127_771803_8	1254432.SCE1572_35470	5.141e-90	310.0	COG2844@1|root,COG2844@2|Bacteria,1P77X@1224|Proteobacteria,433GP@68525|delta/epsilon subdivisions,2WXFN@28221|Deltaproteobacteria,2YW9R@29|Myxococcales	28221|Deltaproteobacteria	O	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD
SHD3_k127_771803_1	1121937.AUHJ01000009_gene1479	6.9e-174	557.0	COG0527@1|root,COG0527@2|Bacteria,1MW3H@1224|Proteobacteria,1RN1G@1236|Gammaproteobacteria,465C7@72275|Alteromonadaceae	1236|Gammaproteobacteria	E	Belongs to the aspartokinase family	thrA	GO:0003674,GO:0003824,GO:0004072,GO:0004412,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.3,2.7.2.4	ko:K12524,ko:K12525	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iECDH1ME8569_1439.ECDH1ME8569_0002,iEcDH1_1363.EcDH1_3594,iSFV_1184.SFV_0001,iUMNK88_1353.UMNK88_4778,iYL1228.KPN_04234	AA_kinase,ACT,ACT_7,Homoserine_dh,NAD_binding_3
SHD3_k127_771803_9	1254432.SCE1572_09795	1.059e-70	250.0	COG3509@1|root,COG3509@2|Bacteria,1N6M6@1224|Proteobacteria,42U8Z@68525|delta/epsilon subdivisions,2WQQT@28221|Deltaproteobacteria,2Z1F1@29|Myxococcales	28221|Deltaproteobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase,Esterase_phd,Peptidase_S9,RicinB_lectin_2
SHD3_k127_771803_14	1192034.CAP_5836	8.156e-22	97.0	COG4636@1|root,COG4636@2|Bacteria,1N1KS@1224|Proteobacteria,43ACX@68525|delta/epsilon subdivisions,2X5SX@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_786228_9	378806.STAUR_0776	1.213e-87	295.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42PIB@68525|delta/epsilon subdivisions,2WKFC@28221|Deltaproteobacteria,2Z2W7@29|Myxococcales	28221|Deltaproteobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	ybhF-N	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
SHD3_k127_786228_7	404589.Anae109_0894	3.292e-109	365.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42MV1@68525|delta/epsilon subdivisions,2WK9W@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC transporter	-	-	-	ko:K01990,ko:K01992,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC2_membrane_3,ABC_tran
SHD3_k127_786228_5	1278073.MYSTI_04096	2.815e-111	374.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42P7V@68525|delta/epsilon subdivisions,2WJQA@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	PFAM ABC-2 type transporter	ybhS	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SHD3_k127_786228_6	378806.STAUR_0779	2.911e-110	372.0	COG0842@1|root,COG0842@2|Bacteria,1MW5R@1224|Proteobacteria,42NC3@68525|delta/epsilon subdivisions,2WIJJ@28221|Deltaproteobacteria,2Z30N@29|Myxococcales	28221|Deltaproteobacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
SHD3_k127_786228_14	640511.BC1002_4255	3.636e-43	167.0	COG0778@1|root,COG0778@2|Bacteria,1RJMP@1224|Proteobacteria,2WG8W@28216|Betaproteobacteria,1KG2B@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
SHD3_k127_786228_2	448385.sce9312	1.726e-157	526.0	COG1629@1|root,COG4771@2|Bacteria,1QX4E@1224|Proteobacteria,437VM@68525|delta/epsilon subdivisions,2X358@28221|Deltaproteobacteria,2YUBU@29|Myxococcales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_C,TonB_dep_Rec
SHD3_k127_786228_0	404589.Anae109_3101	3.157e-216	689.0	COG0531@1|root,COG0531@2|Bacteria,1R829@1224|Proteobacteria,42MS5@68525|delta/epsilon subdivisions,2WINQ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
SHD3_k127_786228_12	391625.PPSIR1_11130	1.377e-57	213.0	COG1262@1|root,COG1262@2|Bacteria,1QADB@1224|Proteobacteria,43503@68525|delta/epsilon subdivisions,2X93Q@28221|Deltaproteobacteria,2Z1R3@29|Myxococcales	28221|Deltaproteobacteria	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_786228_10	398512.JQKC01000005_gene5328	3.15e-84	303.0	COG4412@1|root,COG4412@2|Bacteria,1UIJ6@1239|Firmicutes,24BZI@186801|Clostridia	186801|Clostridia	G	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,CW_binding_1,F5_F8_type_C,Laminin_G_3
SHD3_k127_786228_8	929703.KE386491_gene2941	3.051e-108	366.0	COG3659@1|root,COG3659@2|Bacteria,4NHN1@976|Bacteroidetes,47MFC@768503|Cytophagia	976|Bacteroidetes	M	Carbohydrate-selective porin, OprB family	-	-	-	ko:K16080	-	-	-	-	ko00000,ko02000	1.B.4.2.2	-	-	OprB
SHD3_k127_786228_13	1254432.SCE1572_25715	6.658e-54	211.0	COG5549@1|root,COG5549@2|Bacteria,1PBXR@1224|Proteobacteria,43864@68525|delta/epsilon subdivisions,2X0VV@28221|Deltaproteobacteria,2YVXH@29|Myxococcales	28221|Deltaproteobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
SHD3_k127_786228_3	448385.sce0363	2.578e-119	404.0	COG0515@1|root,COG0515@2|Bacteria,1P913@1224|Proteobacteria,4377Q@68525|delta/epsilon subdivisions,2X28Z@28221|Deltaproteobacteria,2YUDY@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_786228_1	452637.Oter_2476	1.012e-176	566.0	COG0004@1|root,COG0004@2|Bacteria,46SCE@74201|Verrucomicrobia,3K7NK@414999|Opitutae	414999|Opitutae	P	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
SHD3_k127_786228_18	7370.XP_005182163.1	2.195e-06	61.0	COG4886@1|root,KOG1217@1|root,KOG3594@1|root,KOG1217@2759|Eukaryota,KOG1219@2759|Eukaryota,KOG4237@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SKFR@50557|Insecta,4510U@7147|Diptera	33208|Metazoa	T	Calcium ion binding	-	GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066	-	-	-	-	-	-	-	-	-	-	EGF_CA,Zona_pellucida
SHD3_k127_786228_11	391625.PPSIR1_13070	1.143e-77	287.0	COG1506@1|root,COG1506@2|Bacteria,1QX7B@1224|Proteobacteria,431GN@68525|delta/epsilon subdivisions,2WWHZ@28221|Deltaproteobacteria,2YWHU@29|Myxococcales	28221|Deltaproteobacteria	E	Domain of unknown function (DUF4215)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4215,PA14
SHD3_k127_786228_15	1267535.KB906767_gene2841	7.646e-29	130.0	COG2067@1|root,COG2067@2|Bacteria,3Y3JJ@57723|Acidobacteria,2JJB9@204432|Acidobacteriia	204432|Acidobacteriia	I	Putative beta-barrel porin-2, OmpL-like. bbp2	-	-	-	-	-	-	-	-	-	-	-	-	BBP2
SHD3_k127_786228_17	1185876.BN8_00154	2.735e-19	94.0	COG0558@1|root,COG0558@2|Bacteria,4NWDJ@976|Bacteroidetes,47XVU@768503|Cytophagia	976|Bacteroidetes	I	Domain of unknown function (DUF4833)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4833
SHD3_k127_786228_4	1242864.D187_007396	5.603e-115	390.0	COG0667@1|root,COG0667@2|Bacteria,1MVEH@1224|Proteobacteria,42MDR@68525|delta/epsilon subdivisions,2WKUR@28221|Deltaproteobacteria	28221|Deltaproteobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
SHD3_k127_786228_16	290397.Adeh_0115	3.832e-26	113.0	COG0515@1|root,COG0515@2|Bacteria,1MV1P@1224|Proteobacteria,42Q67@68525|delta/epsilon subdivisions,2X566@28221|Deltaproteobacteria,2Z063@29|Myxococcales	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
SHD3_k127_796995_8	584708.Apau_0187	6.203e-10	68.0	COG0023@1|root,COG0023@2|Bacteria	2|Bacteria	J	translation initiation factor activity	yciH	GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K03113	ko03013,map03013	-	-	-	ko00000,ko00001,ko03012	-	-	-	SUI1
SHD3_k127_796995_7	1172190.M947_05515	2.344e-15	84.0	COG4895@1|root,COG4895@2|Bacteria,1N7TD@1224|Proteobacteria,42V1D@68525|delta/epsilon subdivisions,2YQJ3@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	S	Uncharacterized conserved protein (DUF2196)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2196
SHD3_k127_796995_6	448385.sce1829	2.08e-64	238.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42M55@68525|delta/epsilon subdivisions,2WIKM@28221|Deltaproteobacteria,2Z31E@29|Myxococcales	28221|Deltaproteobacteria	C	Iron-sulfur cluster-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_796995_5	1469948.JPNB01000001_gene2276	3.036e-68	245.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,36E8H@31979|Clostridiaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SHD3_k127_796995_9	748247.AZKH_2577	0.0007114	47.0	COG1538@1|root,COG1538@2|Bacteria,1MUA8@1224|Proteobacteria,2VISZ@28216|Betaproteobacteria,2KV30@206389|Rhodocyclales	206389|Rhodocyclales	M	Outer membrane efflux protein	-	-	-	ko:K18903	-	M00698	-	-	ko00000,ko00002,ko01504,ko02000	1.B.17.3.3	-	-	OEP
SHD3_k127_796995_0	1192034.CAP_3241	6.1e-159	523.0	COG3420@1|root,COG3420@2|Bacteria	2|Bacteria	P	alginic acid biosynthetic process	-	-	4.2.2.3	ko:K01729	ko00051,map00051	-	R03706	-	ko00000,ko00001,ko01000	-	-	-	Beta_helix,Chondroitinas_B
SHD3_k127_796995_1	1254432.SCE1572_40265	8.41e-97	321.0	COG0726@1|root,COG0726@2|Bacteria,1R7W4@1224|Proteobacteria,43DTW@68525|delta/epsilon subdivisions,2X8WG@28221|Deltaproteobacteria,2Z0PP@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 11 (cellulase G) family	-	-	3.2.1.8	ko:K01181	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_11
SHD3_k127_796995_3	448385.sce5731	4.671e-72	254.0	COG5297@1|root,COG5297@2|Bacteria,1QARJ@1224|Proteobacteria,43599@68525|delta/epsilon subdivisions,2WZKF@28221|Deltaproteobacteria,2Z2B8@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 12 (cellulase H) family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_12
SHD3_k127_796995_2	290397.Adeh_0028	2.493e-91	310.0	COG0583@1|root,COG0583@2|Bacteria,1MWVB@1224|Proteobacteria,4319Y@68525|delta/epsilon subdivisions,2WWCS@28221|Deltaproteobacteria,2Z023@29|Myxococcales	28221|Deltaproteobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
SHD3_k127_796995_4	290397.Adeh_0027	7.014e-69	241.0	COG0451@1|root,COG0451@2|Bacteria,1MXYR@1224|Proteobacteria,437IW@68525|delta/epsilon subdivisions,2X2SP@28221|Deltaproteobacteria,2YUPD@29|Myxococcales	28221|Deltaproteobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SHD3_k127_801333_0	404589.Anae109_0027	1.264e-51	188.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria	1224|Proteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PocR,Response_reg,RsbRD_N
SHD3_k127_801333_1	448385.sce2173	2.536e-08	60.0	COG0457@1|root,COG0457@2|Bacteria	448385.sce2173|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_801333_2	1077974.GOEFS_017_00430	3.66e-08	63.0	COG1695@1|root,COG1695@2|Bacteria,2IJQK@201174|Actinobacteria,4GDBD@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
SHD3_k127_801333_3	1120936.KB907210_gene5540	6.779e-07	62.0	COG4447@1|root,COG4447@2|Bacteria,2HEKQ@201174|Actinobacteria,4EQ2R@85012|Streptosporangiales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_801333_4	1172180.KB911783_gene2190	0.0003572	53.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3,Pkinase
SHD3_k127_840802_0	1254432.SCE1572_25880	8.402e-209	660.0	COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,42MAH@68525|delta/epsilon subdivisions,2WJT7@28221|Deltaproteobacteria,2YTXJ@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
SHD3_k127_840802_7	448385.sce4280	1.313e-24	108.0	COG0721@1|root,COG0721@2|Bacteria,1QE6H@1224|Proteobacteria,42VPR@68525|delta/epsilon subdivisions,2WRP0@28221|Deltaproteobacteria,2YW6Q@29|Myxococcales	28221|Deltaproteobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	iAF987.Gmet_0076	Glu-tRNAGln
SHD3_k127_840802_5	448385.sce7602	4.296e-58	222.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce7602|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_840802_6	1173025.GEI7407_0097	1.965e-54	203.0	COG1218@1|root,COG1218@2|Bacteria,1G1Z4@1117|Cyanobacteria,1H7F9@1150|Oscillatoriales	1117|Cyanobacteria	P	3'(2'),5'-bisphosphate nucleotidase	-	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
SHD3_k127_840802_2	1128421.JAGA01000003_gene3206	7.925e-113	381.0	COG0381@1|root,COG0381@2|Bacteria,2NNVT@2323|unclassified Bacteria	2|Bacteria	M	UDP-N-acetylglucosamine 2-epimerase	wecB	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
SHD3_k127_840802_1	448385.sce3132	7.38e-119	389.0	COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,42M3Y@68525|delta/epsilon subdivisions,2WJH5@28221|Deltaproteobacteria,2YTZQ@29|Myxococcales	28221|Deltaproteobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
SHD3_k127_840802_3	1254432.SCE1572_18905	4.565e-82	286.0	COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,42NNS@68525|delta/epsilon subdivisions,2WMS3@28221|Deltaproteobacteria,2YVCJ@29|Myxococcales	28221|Deltaproteobacteria	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
SHD3_k127_840802_4	1254432.SCE1572_32275	8.171e-62	220.0	COG4636@1|root,COG4636@2|Bacteria	2|Bacteria	D	protein conserved in cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
SHD3_k127_840802_9	313612.L8106_15525	3.205e-17	93.0	2DRDY@1|root,33BC0@2|Bacteria,1G9R7@1117|Cyanobacteria,1HCUI@1150|Oscillatoriales	1117|Cyanobacteria	S	Coenzyme PQQ synthesis protein D (PqqD)	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
SHD3_k127_840802_10	1248917.ANFX01000035_gene1938	1.523e-11	70.0	2ESXU@1|root,33KG4@2|Bacteria,1NMBC@1224|Proteobacteria	1224|Proteobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core3
SHD3_k127_840802_8	329726.AM1_1917	1.307e-18	100.0	COG1493@1|root,COG1493@2|Bacteria,1G614@1117|Cyanobacteria	1117|Cyanobacteria	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_859017_2	1254432.SCE1572_39610	8.636e-47	170.0	COG5520@1|root,COG5520@2|Bacteria,1N9T9@1224|Proteobacteria,43836@68525|delta/epsilon subdivisions,2X3D4@28221|Deltaproteobacteria,2YVHE@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the glycosyl hydrolase 30 family	srfJ	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	Glyco_hydro_30,Glyco_hydro_30C,RicinB_lectin_2
SHD3_k127_859017_0	1291050.JAGE01000002_gene3671	1.62e-114	385.0	COG3345@1|root,COG3345@2|Bacteria,1U52C@1239|Firmicutes,25FA2@186801|Clostridia,3WJWC@541000|Ruminococcaceae	186801|Clostridia	G	Alpha galactosidase A	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Dockerin_1,Melibiase_2
SHD3_k127_859017_1	1254432.SCE1572_11400	8.317e-105	356.0	COG3509@1|root,COG3509@2|Bacteria,1MXUI@1224|Proteobacteria	1224|Proteobacteria	Q	Esterase, phb depolymerase family	phaZ1	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
SHD3_k127_861997_12	1192034.CAP_3517	1.843e-07	61.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
SHD3_k127_861997_5	404589.Anae109_3067	3.412e-126	430.0	COG1948@1|root,COG4880@2|Bacteria,1PQKR@1224|Proteobacteria,438JJ@68525|delta/epsilon subdivisions,2X3U8@28221|Deltaproteobacteria,2YX4D@29|Myxococcales	28221|Deltaproteobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
SHD3_k127_861997_13	502025.Hoch_2959	1.265e-06	51.0	COG2801@1|root,COG2801@2|Bacteria,1P5SB@1224|Proteobacteria,4313Z@68525|delta/epsilon subdivisions,2WX2K@28221|Deltaproteobacteria,2Z2QP@29|Myxococcales	28221|Deltaproteobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
SHD3_k127_861997_2	68223.JNZY01000008_gene2785	9.481e-213	690.0	COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria,2GJF7@201174|Actinobacteria	201174|Actinobacteria	G	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR,RicinB_lectin_2
SHD3_k127_861997_10	1142394.PSMK_00920	3.71e-23	108.0	28HQ2@1|root,2Z7XV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_861997_11	1142394.PSMK_00920	1.66e-14	78.0	28HQ2@1|root,2Z7XV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_861997_7	448385.sce7194	6.424e-76	264.0	COG0515@1|root,COG0515@2|Bacteria	448385.sce7194|-	KLT	protein kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_861997_3	448385.sce8545	6.528e-197	636.0	COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,42MMK@68525|delta/epsilon subdivisions,2WJC1@28221|Deltaproteobacteria,2YU05@29|Myxococcales	28221|Deltaproteobacteria	S	ABC transporter	uup	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
SHD3_k127_861997_1	1205753.A989_01575	3.915e-231	733.0	COG1874@1|root,COG1874@2|Bacteria,1MUVR@1224|Proteobacteria,1RPW9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	beta-galactosidase	bglY	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
SHD3_k127_861997_4	378806.STAUR_4922	6.776e-143	494.0	COG0457@1|root,COG0775@1|root,COG0457@2|Bacteria,COG0775@2|Bacteria,1R9KT@1224|Proteobacteria,42XBH@68525|delta/epsilon subdivisions,2WTEV@28221|Deltaproteobacteria,2YUPK@29|Myxococcales	28221|Deltaproteobacteria	F	Anaphase-promoting complex subunit 5	-	-	-	-	-	-	-	-	-	-	-	-	ANAPC5,TPR_10
SHD3_k127_861997_0	1120972.AUMH01000008_gene2024	6.632e-278	878.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli	91061|Bacilli	G	Belongs to the glycosyl hydrolase 31 family	yicI	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
SHD3_k127_861997_9	903818.KI912268_gene2977	2.153e-45	181.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
SHD3_k127_861997_6	1142394.PSMK_10690	1.969e-117	386.0	COG1087@1|root,COG1087@2|Bacteria,2IY22@203682|Planctomycetes	203682|Planctomycetes	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
SHD3_k127_861997_8	631362.Thi970DRAFT_01668	3.885e-66	244.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,1RMR1@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Pyrroloquinoline quinone biosynthesis protein E	pqqE	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
SHD3_k127_869112_1	3988.XP_002523703.1	8.031e-79	290.0	COG3669@1|root,KOG3340@2759|Eukaryota,37NEY@33090|Viridiplantae,3GGSX@35493|Streptophyta,4JIIF@91835|fabids	35493|Streptophyta	G	alpha-L-fucosidase	-	GO:0003674,GO:0003824,GO:0004553,GO:0004560,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0006516,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009100,GO:0009987,GO:0015928,GO:0016787,GO:0016798,GO:0019538,GO:0030163,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
SHD3_k127_869112_0	394503.Ccel_1239	5.011e-265	847.0	COG3250@1|root,COG3507@1|root,COG3250@2|Bacteria,COG3507@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,36FQM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Big_3,Big_4,CBM_6,DUF4982,F5_F8_type_C,FIVAR,Glyco_hydro_2,Glyco_hydro_20b,Glyco_hydro_2_C,Glyco_hydro_2_N,NAGidase
SHD3_k127_876051_4	1035308.AQYY01000002_gene390	2.96e-32	128.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,249J4@186801|Clostridia,264FI@186807|Peptococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	panE	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SHD3_k127_876051_7	762903.Pedsa_0673	9.5e-06	55.0	COG0845@1|root,COG0845@2|Bacteria,4NG8S@976|Bacteroidetes,1IPFI@117747|Sphingobacteriia	976|Bacteroidetes	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K07798	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.6.1.4,8.A.1	-	-	DUF3347,HlyD_D23
SHD3_k127_876051_1	1242864.D187_010114	1.278e-93	324.0	COG3829@1|root,COG3829@2|Bacteria,1NU8B@1224|Proteobacteria	1224|Proteobacteria	K	PFAM sigma-54 factor interaction domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_876051_2	448385.sce1683	2.673e-77	284.0	COG4221@1|root,COG4221@2|Bacteria,1QVCA@1224|Proteobacteria,431MP@68525|delta/epsilon subdivisions,2WWCC@28221|Deltaproteobacteria,2Z3JH@29|Myxococcales	28221|Deltaproteobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_876051_0	765914.ThisiDRAFT_1231	4.661e-181	577.0	COG0369@1|root,COG1151@2|Bacteria,1N88B@1224|Proteobacteria,1RP1I@1236|Gammaproteobacteria,1WWDV@135613|Chromatiales	135613|Chromatiales	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
SHD3_k127_876051_3	595460.RRSWK_02165	5.626e-48	181.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
SHD3_k127_876338_2	290397.Adeh_3529	1.42e-153	527.0	COG0642@1|root,COG0784@1|root,COG2461@1|root,COG5002@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG2461@2|Bacteria,COG5002@2|Bacteria,1NRP8@1224|Proteobacteria,43CCU@68525|delta/epsilon subdivisions,2X7NQ@28221|Deltaproteobacteria,2YX99@29|Myxococcales	28221|Deltaproteobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
SHD3_k127_876338_5	246197.MXAN_6979	2.791e-87	307.0	COG4191@1|root,COG4191@2|Bacteria,1MWR3@1224|Proteobacteria,42WNA@68525|delta/epsilon subdivisions,2WRKM@28221|Deltaproteobacteria,2YUJ7@29|Myxococcales	28221|Deltaproteobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K15011	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
SHD3_k127_876338_12	483219.LILAB_11515	3.414e-56	207.0	COG4567@1|root,COG4567@2|Bacteria,1RD7J@1224|Proteobacteria,42ZS1@68525|delta/epsilon subdivisions,2WV25@28221|Deltaproteobacteria,2YV5R@29|Myxococcales	28221|Deltaproteobacteria	T	Bacterial regulatory protein, Fis family	-	-	-	ko:K15012	ko02020,map02020	M00523	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg
SHD3_k127_876338_4	1280390.CBQR020000153_gene4094	3.302e-89	313.0	COG0535@1|root,COG0535@2|Bacteria,1TQGZ@1239|Firmicutes,4HFKU@91061|Bacilli	1239|Firmicutes	C	Nitrogen fixation protein NifB	-	-	-	ko:K02585	-	-	-	-	ko00000	-	-	-	Nitro_FeMo-Co,Radical_SAM
SHD3_k127_876338_20	1168289.AJKI01000053_gene817	2.566e-07	64.0	COG3934@1|root,COG3934@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 5 (cellulase A) family	-	-	3.2.1.78	ko:K19355	ko00051,map00051	-	R01332	RC00467	ko00000,ko00001,ko01000	-	-	-	CBM_11,Cellulase
SHD3_k127_876338_13	760192.Halhy_3968	1.932e-44	183.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Peptidase_C14
SHD3_k127_876338_0	1123278.KB893615_gene5179	2.339e-175	576.0	COG3386@1|root,COG3391@1|root,COG3386@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,47PBP@768503|Cytophagia	976|Bacteroidetes	G	NHL repeat	-	-	-	-	-	-	-	-	-	-	-	-	NHL
SHD3_k127_876338_7	266117.Rxyl_0877	7.084e-82	293.0	COG0793@1|root,COG0793@2|Bacteria,2GKRP@201174|Actinobacteria,4CPMI@84995|Rubrobacteria	84995|Rubrobacteria	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
SHD3_k127_876338_14	448385.sce6234	2.025e-35	145.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SHD3_k127_876338_1	903818.KI912268_gene3327	5.455e-154	504.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cyt_bd_oxida_I,Cytochrome_CBB3
SHD3_k127_876338_10	1242864.D187_010025	1.534e-67	246.0	COG0693@1|root,COG0693@2|Bacteria,1MYPJ@1224|Proteobacteria,42RVZ@68525|delta/epsilon subdivisions,2X5WP@28221|Deltaproteobacteria,2YYGJ@29|Myxococcales	28221|Deltaproteobacteria	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
SHD3_k127_876338_6	497964.CfE428DRAFT_6538	3.453e-85	293.0	COG0500@1|root,COG0500@2|Bacteria,46Z8Z@74201|Verrucomicrobia	74201|Verrucomicrobia	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_2
SHD3_k127_876338_8	304371.MCP_0739	3.967e-79	283.0	COG0535@1|root,arCOG00938@2157|Archaea,2Y8D0@28890|Euryarchaeota	28890|Euryarchaeota	S	PFAM Radical SAM domain protein	pqqE	-	-	ko:K15045,ko:K22227	ko05164,map05164	-	-	-	ko00000,ko00001	-	-	-	Fer4_12,Radical_SAM,SPASM
SHD3_k127_876338_16	1254432.SCE1572_50395	1.131e-30	135.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
SHD3_k127_876338_21	448385.sce1338	5.427e-07	61.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_876338_3	105559.Nwat_2023	1.872e-114	382.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1MY9R@1224|Proteobacteria,1S28T@1236|Gammaproteobacteria,1WY61@135613|Chromatiales	135613|Chromatiales	S	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50,Peptidase_M50B
SHD3_k127_876338_15	316067.Geob_2063	1.121e-31	135.0	COG1266@1|root,COG1266@2|Bacteria	2|Bacteria	V	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
SHD3_k127_876338_11	1232410.KI421428_gene1178	5.548e-62	228.0	COG0596@1|root,COG0596@2|Bacteria,1RGAP@1224|Proteobacteria,42XWU@68525|delta/epsilon subdivisions,2WSMY@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	Alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
SHD3_k127_876338_17	1340493.JNIF01000004_gene520	1.524e-24	119.0	COG1520@1|root,COG1520@2|Bacteria,3Y5TU@57723|Acidobacteria	57723|Acidobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	VPEP
SHD3_k127_876338_9	1041147.AUFB01000015_gene997	2.048e-72	255.0	COG1028@1|root,COG1028@2|Bacteria,1MUCH@1224|Proteobacteria,2TQRM@28211|Alphaproteobacteria,4B7EU@82115|Rhizobiaceae	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114	-	-	-	-	-	-	-	-	-	-	adh_short
SHD3_k127_880321_1	1192034.CAP_9011	6.378e-194	617.0	COG1109@1|root,COG1109@2|Bacteria,1MU24@1224|Proteobacteria,42M6I@68525|delta/epsilon subdivisions,2WJTV@28221|Deltaproteobacteria,2YU3G@29|Myxococcales	28221|Deltaproteobacteria	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1886	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
SHD3_k127_880321_3	1254432.SCE1572_34380	5.371e-85	304.0	COG0285@1|root,COG0285@2|Bacteria,1MVCH@1224|Proteobacteria,42N08@68525|delta/epsilon subdivisions,2WIW9@28221|Deltaproteobacteria,2YUTG@29|Myxococcales	28221|Deltaproteobacteria	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2475	Mur_ligase_C,Mur_ligase_M
SHD3_k127_880321_2	1254432.SCE1572_34375	2.637e-115	378.0	COG0777@1|root,COG0777@2|Bacteria,1MW8G@1224|Proteobacteria,42MAB@68525|delta/epsilon subdivisions,2WK95@28221|Deltaproteobacteria,2YU1S@29|Myxococcales	28221|Deltaproteobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
SHD3_k127_880321_0	1254432.SCE1572_34345	7.303e-204	664.0	COG0457@1|root,COG1672@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,1NB06@1224|Proteobacteria,43AS1@68525|delta/epsilon subdivisions,2X665@28221|Deltaproteobacteria,2YYB2@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,TPR_12,TPR_8
SHD3_k127_880321_4	1192034.CAP_8097	3.701e-54	193.0	COG0756@1|root,COG0756@2|Bacteria,1RA7P@1224|Proteobacteria,42SJS@68525|delta/epsilon subdivisions,2WP7N@28221|Deltaproteobacteria,2YV9H@29|Myxococcales	28221|Deltaproteobacteria	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
SHD3_k127_880321_5	1229204.AMYY01000036_gene2084	0.0001228	47.0	COG5573@1|root,COG5573@2|Bacteria,1N9U9@1224|Proteobacteria,2VEQF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
SHD3_k127_893316_0	448385.sce8496	3.044e-59	216.0	COG1893@1|root,COG1893@2|Bacteria,1MX5M@1224|Proteobacteria,42SX1@68525|delta/epsilon subdivisions,2X5WJ@28221|Deltaproteobacteria,2YY1T@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
SHD3_k127_893316_1	591167.Sfla_5112	2.762e-09	70.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
SHD3_k127_904655_13	1336208.JADY01000001_gene1182	5.488e-07	59.0	COG0784@1|root,COG4191@1|root,COG0784@2|Bacteria,COG4191@2|Bacteria,1RCM9@1224|Proteobacteria,2TQQ9@28211|Alphaproteobacteria	28211|Alphaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg
SHD3_k127_904655_11	1192034.CAP_1239	3.299e-23	109.0	COG0727@1|root,COG0727@2|Bacteria,1RCAS@1224|Proteobacteria,43BA4@68525|delta/epsilon subdivisions,2X8W3@28221|Deltaproteobacteria,2Z3C1@29|Myxococcales	28221|Deltaproteobacteria	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
SHD3_k127_904655_0	215803.DB30_0565	8.356e-240	762.0	COG3591@1|root,COG3591@2|Bacteria,1MX71@1224|Proteobacteria,438V6@68525|delta/epsilon subdivisions,2X414@28221|Deltaproteobacteria,2YXVR@29|Myxococcales	28221|Deltaproteobacteria	E	Peptidase S46	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S46
SHD3_k127_904655_4	448385.sce3764	1.027e-104	352.0	COG0524@1|root,COG0524@2|Bacteria,1Q8Y3@1224|Proteobacteria,42NSV@68525|delta/epsilon subdivisions,2WJWD@28221|Deltaproteobacteria,2YU0F@29|Myxococcales	28221|Deltaproteobacteria	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	iAF987.Gmet_2683	PfkB
SHD3_k127_904655_5	1254432.SCE1572_22635	7.421e-102	339.0	COG0005@1|root,COG0005@2|Bacteria,1MUWW@1224|Proteobacteria,42P5B@68525|delta/epsilon subdivisions,2WM02@28221|Deltaproteobacteria,2YUVV@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates	mtnP	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.28	ko:K00772	ko00270,ko01100,map00270,map01100	M00034	R01402	RC00063,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2684	PNP_UDP_1
SHD3_k127_904655_7	448385.sce3761	3.85e-72	253.0	COG1561@1|root,COG1561@2|Bacteria,1MWRA@1224|Proteobacteria,42RFR@68525|delta/epsilon subdivisions,2WJYK@28221|Deltaproteobacteria,2YVIN@29|Myxococcales	28221|Deltaproteobacteria	S	Domain of unknown function (DUF1732)	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
SHD3_k127_904655_3	1192034.CAP_6915	4.866e-129	419.0	COG0451@1|root,COG0451@2|Bacteria,1MU7J@1224|Proteobacteria,42MRN@68525|delta/epsilon subdivisions,2WJCH@28221|Deltaproteobacteria,2YZUS@29|Myxococcales	28221|Deltaproteobacteria	M	Polysaccharide biosynthesis protein	-	-	5.1.3.2,5.1.3.7	ko:K01784,ko:K02473	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R00418,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
SHD3_k127_904655_8	448385.sce3758	1.706e-44	172.0	COG2952@1|root,COG2952@2|Bacteria,1QJIU@1224|Proteobacteria,43826@68525|delta/epsilon subdivisions,2X3CC@28221|Deltaproteobacteria,2YVDW@29|Myxococcales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF507)	-	-	-	ko:K09804	-	-	-	-	ko00000	-	-	-	DUF507
SHD3_k127_904655_2	448385.sce3756	3.518e-138	450.0	2BKCR@1|root,32ETA@2|Bacteria,1RJ21@1224|Proteobacteria,430EX@68525|delta/epsilon subdivisions,2WVVF@28221|Deltaproteobacteria,2YUQK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_904655_6	391625.PPSIR1_10130	1.778e-72	261.0	COG2204@1|root,COG2204@2|Bacteria	2|Bacteria	T	phosphorelay signal transduction system	-	-	-	ko:K10941	ko02020,ko02025,ko05111,map02020,map02025,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	FHA,GAF_2,HTH_8,Sigma54_activat,Yop-YscD_cpl
SHD3_k127_904655_10	1254432.SCE1572_22585	1.997e-23	108.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K00406,ko:K03889	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00151,M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3
SHD3_k127_904655_9	1254432.SCE1572_34820	1.096e-32	136.0	COG2885@1|root,COG2885@2|Bacteria	2|Bacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
SHD3_k127_904655_1	1254432.SCE1572_22570	2.429e-238	751.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,2YU4G@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
SHD3_k127_92116_1	448385.sce5472	1.152e-115	378.0	COG1842@1|root,COG1842@2|Bacteria,1NC7S@1224|Proteobacteria,42VIT@68525|delta/epsilon subdivisions,2WS62@28221|Deltaproteobacteria,2YZJ3@29|Myxococcales	28221|Deltaproteobacteria	KT	PspA/IM30 family	-	-	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
SHD3_k127_92116_3	448385.sce5471	4.603e-33	132.0	2E9HN@1|root,333QR@2|Bacteria,1QTQ2@1224|Proteobacteria,4359W@68525|delta/epsilon subdivisions,2WZKZ@28221|Deltaproteobacteria,2Z2CN@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_92116_0	1192034.CAP_7478	1.52e-235	736.0	COG0516@1|root,COG0516@2|Bacteria,1MUJM@1224|Proteobacteria,42M2M@68525|delta/epsilon subdivisions,2WJ5H@28221|Deltaproteobacteria,2YUG2@29|Myxococcales	28221|Deltaproteobacteria	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
SHD3_k127_92116_5	1120949.KB903326_gene3138	9.8e-25	120.0	COG1361@1|root,COG3250@1|root,COG3533@1|root,COG5297@1|root,COG1361@2|Bacteria,COG3250@2|Bacteria,COG3533@2|Bacteria,COG5297@2|Bacteria,2GJXK@201174|Actinobacteria,4DHTI@85008|Micromonosporales	201174|Actinobacteria	G	Alpha-L-arabinofuranosidase B, catalytic	-	-	-	-	-	-	-	-	-	-	-	-	AbfB,ArabFuran-catal
SHD3_k127_92116_4	644966.Tmar_1896	2.001e-25	119.0	COG3547@1|root,COG3547@2|Bacteria,1VI3C@1239|Firmicutes,25AXZ@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS116 IS110 IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
SHD3_k127_929551_0	279010.BL05207	0.0	1245.0	COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,4IS5E@91061|Bacilli,1ZS18@1386|Bacillus	91061|Bacilli	C	formate dehydrogenase (NAD+) activity	yjgC	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114	1.17.1.9	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
SHD3_k127_929551_1	1158345.JNLL01000001_gene877	4.92e-36	153.0	COG3746@1|root,COG3746@2|Bacteria,2G5GY@200783|Aquificae	200783|Aquificae	P	Phosphate-selective porin O and P	-	-	-	-	-	-	-	-	-	-	-	-	Porin_O_P
SHD3_k127_96387_1	448385.sce4292	2.531e-110	366.0	COG1472@1|root,COG1472@2|Bacteria,1MVAJ@1224|Proteobacteria,42N8K@68525|delta/epsilon subdivisions,2WN0Z@28221|Deltaproteobacteria,2YUJN@29|Myxococcales	28221|Deltaproteobacteria	G	Glycosyl hydrolase family 3 N terminal domain	nagZ	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
SHD3_k127_96387_2	1254432.SCE1572_26335	1.555e-100	342.0	2ANEP@1|root,31DDB@2|Bacteria,1QAJQ@1224|Proteobacteria,434DJ@68525|delta/epsilon subdivisions,2X8U1@28221|Deltaproteobacteria,2Z0DK@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_96387_4	7029.ACYPI060717-PA	1.701e-07	64.0	KOG1217@1|root,KOG1217@2759|Eukaryota,38BUP@33154|Opisthokonta,3BA2W@33208|Metazoa,3CUNH@33213|Bilateria,41VHE@6656|Arthropoda,3SX05@50557|Insecta,3EC26@33342|Paraneoptera	33208|Metazoa	T	Worm-specific repeat type 1	-	-	-	-	-	-	-	-	-	-	-	-	EGF_CA,NIDO,hEGF
SHD3_k127_96387_3	1254432.SCE1572_26330	5.402e-33	132.0	COG2442@1|root,COG2442@2|Bacteria	2|Bacteria	K	InterPro IPR007367	-	-	-	-	-	-	-	-	-	-	-	-	DUF433
SHD3_k127_96387_0	398767.Glov_2804	8.16e-207	662.0	COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,42M80@68525|delta/epsilon subdivisions,2WINJ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	tkt	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
SHD3_k127_964697_5	1071073.KI530536_gene1074	2.226e-81	278.0	COG3386@1|root,COG3386@2|Bacteria,1V1TK@1239|Firmicutes,4HG0A@91061|Bacilli,1ZAVX@1386|Bacillus	91061|Bacilli	G	SMP-30/Gluconolaconase/LRE-like region	yvrE	GO:0003674,GO:0003824,GO:0004341,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005975,GO:0005996,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016051,GO:0016053,GO:0016787,GO:0016788,GO:0019752,GO:0019852,GO:0019853,GO:0042364,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0052689,GO:0071704,GO:1901576	-	ko:K14274	ko00040,map00040	-	R02427	RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
SHD3_k127_964697_14	1142394.PSMK_01890	7.924e-07	55.0	28J96@1|root,2Z947@2|Bacteria	2|Bacteria	S	PFAM Oligopeptide transporter OPT superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_964697_3	219305.MCAG_00247	1.917e-135	437.0	COG0395@1|root,COG0395@2|Bacteria,2GJPQ@201174|Actinobacteria,4DBTJ@85008|Micromonosporales	201174|Actinobacteria	G	binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
SHD3_k127_964697_2	219305.MCAG_00248	2.74e-158	517.0	COG4209@1|root,COG4209@2|Bacteria,2GKSR@201174|Actinobacteria,4D8J4@85008|Micromonosporales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
SHD3_k127_964697_0	219305.MCAG_00249	7.985e-224	706.0	COG1653@1|root,COG1653@2|Bacteria,2GN8J@201174|Actinobacteria,4D8XX@85008|Micromonosporales	201174|Actinobacteria	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8
SHD3_k127_964697_4	1089548.KI783301_gene547	1.273e-126	415.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli,3WEIN@539002|Bacillales incertae sedis	91061|Bacilli	P	ABC transporter	msmX	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
SHD3_k127_964697_12	1379270.AUXF01000001_gene2005	6.786e-07	58.0	COG2010@1|root,COG2010@2|Bacteria,1ZV0S@142182|Gemmatimonadetes	142182|Gemmatimonadetes	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	ko:K08738	ko00920,ko01100,ko01120,ko01524,ko02020,ko04115,ko04210,ko04214,ko04215,ko04932,ko05010,ko05012,ko05014,ko05016,ko05134,ko05145,ko05152,ko05161,ko05164,ko05167,ko05168,ko05200,ko05210,ko05222,ko05416,map00920,map01100,map01120,map01524,map02020,map04115,map04210,map04214,map04215,map04932,map05010,map05012,map05014,map05016,map05134,map05145,map05152,map05161,map05164,map05167,map05168,map05200,map05210,map05222,map05416	M00595	R10151	RC03151,RC03152	ko00000,ko00001,ko00002	3.D.4.6	-	-	Cytochrome_CBB3
SHD3_k127_964697_8	1089544.KB912942_gene3008	1.13e-23	109.0	COG0451@1|root,COG0451@2|Bacteria,2GP24@201174|Actinobacteria,4E0PP@85010|Pseudonocardiales	201174|Actinobacteria	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
SHD3_k127_964697_7	1254432.SCE1572_09715	1.751e-24	114.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigD	GO:0000988,GO:0000990,GO:0002791,GO:0003674,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0016987,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032879,GO:0032880,GO:0043254,GO:0044087,GO:0044419,GO:0050708,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051049,GO:0051128,GO:0051171,GO:0051223,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070201,GO:0080090,GO:0090087,GO:0140110,GO:1903506,GO:1903530,GO:2000112,GO:2000142,GO:2001141	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
SHD3_k127_964697_9	448385.sce7834	8.571e-15	86.0	COG0457@1|root,COG0457@2|Bacteria,1QAUJ@1224|Proteobacteria,43E41@68525|delta/epsilon subdivisions,2X97M@28221|Deltaproteobacteria,2Z2EX@29|Myxococcales	28221|Deltaproteobacteria	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_964697_1	1254432.SCE1572_45505	1.389e-188	605.0	COG0507@1|root,COG0507@2|Bacteria,1MW43@1224|Proteobacteria,42M8J@68525|delta/epsilon subdivisions,2WJD6@28221|Deltaproteobacteria,2YTW8@29|Myxococcales	28221|Deltaproteobacteria	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
SHD3_k127_988361_6	357808.RoseRS_2451	2.851e-65	248.0	COG4870@1|root,COG4932@1|root,COG5513@1|root,COG4870@2|Bacteria,COG4932@2|Bacteria,COG5513@2|Bacteria,2GA24@200795|Chloroflexi,377PH@32061|Chloroflexia	2|Bacteria	MO	Carboxypeptidase regulatory-like domain	-	-	3.4.22.15	ko:K01365,ko:K02030,ko:K14475	ko04140,ko04142,ko04145,ko04210,ko04612,ko05143,ko05205,ko05323,ko05418,map04140,map04142,map04145,map04210,map04612,map05143,map05205,map05323,map05418	M00236	-	-	ko00000,ko00001,ko00002,ko00537,ko01000,ko01002,ko02000,ko03110	3.A.1.3	-	-	CarboxypepD_reg,Inhibitor_I42,Peptidase_C1
SHD3_k127_988361_1	448385.sce2429	8.71e-119	403.0	COG3225@1|root,COG3225@2|Bacteria,1MUXW@1224|Proteobacteria,42MRY@68525|delta/epsilon subdivisions,2WJ4F@28221|Deltaproteobacteria,2Z1RF@29|Myxococcales	28221|Deltaproteobacteria	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC_transp_aux
SHD3_k127_988361_3	1192034.CAP_7501	1.032e-85	298.0	COG1277@1|root,COG1277@2|Bacteria,1NZZ9@1224|Proteobacteria,42SH9@68525|delta/epsilon subdivisions,2WPWW@28221|Deltaproteobacteria,2Z111@29|Myxococcales	28221|Deltaproteobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
SHD3_k127_988361_2	1254432.SCE1572_14660	1.58e-108	363.0	COG1131@1|root,COG1131@2|Bacteria,1MUX3@1224|Proteobacteria,42NF6@68525|delta/epsilon subdivisions,2WKVH@28221|Deltaproteobacteria	28221|Deltaproteobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
SHD3_k127_988361_8	448385.sce5487	3.488e-43	170.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,1MV1P@1224|Proteobacteria,430N6@68525|delta/epsilon subdivisions,2WVRE@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,Pkinase
SHD3_k127_988361_0	448385.sce9312	1.028e-184	604.0	COG1629@1|root,COG4771@2|Bacteria,1QX4E@1224|Proteobacteria,437VM@68525|delta/epsilon subdivisions,2X358@28221|Deltaproteobacteria,2YUBU@29|Myxococcales	28221|Deltaproteobacteria	P	TonB-dependent Receptor Plug Domain	-	-	-	-	-	-	-	-	-	-	-	-	Plug,TonB_C,TonB_dep_Rec
SHD3_k127_988361_7	448385.sce3783	1.579e-43	172.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,HdeA
SHD3_k127_988361_10	1089553.Tph_c00400	6.584e-11	70.0	COG1664@1|root,COG1664@2|Bacteria,1VEVU@1239|Firmicutes,24QT5@186801|Clostridia,42GQS@68295|Thermoanaerobacterales	186801|Clostridia	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
SHD3_k127_988361_9	448385.sce2058	1.849e-39	162.0	2B33H@1|root,31VR5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
SHD3_k127_988361_5	1254432.SCE1572_30835	1.259e-68	239.0	COG2834@1|root,COG2834@2|Bacteria,1PDTV@1224|Proteobacteria,42TAB@68525|delta/epsilon subdivisions,2WPXY@28221|Deltaproteobacteria,2YVS1@29|Myxococcales	28221|Deltaproteobacteria	M	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)	lolA	-	-	ko:K03634	-	-	-	-	ko00000	-	-	-	LolA
SHD3_k127_99314_0	1185876.BN8_03780	2.627e-37	158.0	COG2374@1|root,COG3250@1|root,COG3509@1|root,COG4733@1|root,COG5297@1|root,COG2374@2|Bacteria,COG3250@2|Bacteria,COG3509@2|Bacteria,COG4733@2|Bacteria,COG5297@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase family 6	xynX1	-	3.1.3.8,3.2.1.23	ko:K01083,ko:K01190	ko00052,ko00511,ko00562,ko00600,ko01100,map00052,map00511,map00562,map00600,map01100	-	R01105,R01678,R03355,R03371,R04783,R06114	RC00049,RC00078,RC00452	ko00000,ko00001,ko01000	-	-	-	Exo_endo_phos,F5_F8_type_C,LTD,Laminin_G_3,SLH
SHD3_k127_99314_1	545695.TREAZ_1844	7.295e-37	145.0	COG2318@1|root,COG2318@2|Bacteria,2J94Z@203691|Spirochaetes	203691|Spirochaetes	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DinB
## 5997 queries scanned
## Total time (seconds): 339.2435109615326
## Rate: 17.68 q/s