## Fri Nov 15 14:30:54 2024 ## emapper-2.1.12 ## /data/home/zkh/miniconda3/envs/eggnog-mapper/bin/emapper.py -i /data/home/zkh/binning/bin_4635/bin/bin22/SJTD_3_bin.35.fa -m mmseqs --itype genome -o SJTD_3_bin.35 --output_dir /data/home/zkh/meta_analysis/eggnog-mapper/4635/SJTD_3_bin.35 --cpu 28 ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs SJTD3_k127_1005697_2 661478.OP10G_2830 3.989e-20 93.0 COG0489@1|root,COG0489@2|Bacteria 2|Bacteria D protein tyrosine kinase activity mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA SJTD3_k127_1005697_1 1267535.KB906767_gene735 2.642e-38 156.0 COG1073@1|root,COG1073@2|Bacteria,3Y5TG@57723|Acidobacteria,2JNP5@204432|Acidobacteriia 204432|Acidobacteriia S Serine aminopeptidase, S33 - - - - - - - - - - - - - SJTD3_k127_1005697_0 485913.Krac_12092 1.639e-181 581.0 COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi 200795|Chloroflexi I PFAM carboxyl transferase - - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans SJTD3_k127_1011000_0 1382356.JQMP01000004_gene471 2.232e-117 392.0 COG0472@1|root,COG0472@2|Bacteria,2G5TJ@200795|Chloroflexi,27Y23@189775|Thermomicrobia 189775|Thermomicrobia M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4 SJTD3_k127_1011000_1 926550.CLDAP_38140 1.51e-49 181.0 COG0770@1|root,COG0770@2|Bacteria,2G5PN@200795|Chloroflexi 200795|Chloroflexi M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SJTD3_k127_101170_4 1007103.AFHW01000035_gene1898 3.381e-10 68.0 COG4709@1|root,COG4709@2|Bacteria,1VE8I@1239|Firmicutes,4HN2C@91061|Bacilli,26Y07@186822|Paenibacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - DUF1700 SJTD3_k127_101170_6 1519464.HY22_05255 0.0005212 51.0 2ETC6@1|root,33KW3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_101170_0 316274.Haur_4710 1.337e-70 241.0 COG1225@1|root,COG1225@2|Bacteria,2G6TX@200795|Chloroflexi,37744@32061|Chloroflexia 32061|Chloroflexia O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SJTD3_k127_101170_3 298654.FraEuI1c_6618 1.602e-21 96.0 COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria 201174|Actinobacteria S Putative zinc-finger - - - - - - - - - - - - zf-HC2 SJTD3_k127_101170_1 404589.Anae109_3622 1.597e-61 219.0 COG1595@1|root,COG1595@2|Bacteria,1RI7C@1224|Proteobacteria,42XJU@68525|delta/epsilon subdivisions,2WT13@28221|Deltaproteobacteria,2Z11E@29|Myxococcales 28221|Deltaproteobacteria K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_101170_2 485913.Krac_11442 2.554e-53 199.0 COG0580@1|root,COG0580@2|Bacteria 2|Bacteria U water channel activity glpF - - ko:K02440,ko:K06188,ko:K09874 - - - - ko00000,ko02000 1.A.8,1.A.8.1,1.A.8.12,1.A.8.2 - - MIP SJTD3_k127_101170_5 313612.L8106_16604 4.911e-08 66.0 COG4990@1|root,COG4990@2|Bacteria,1G1Y5@1117|Cyanobacteria,1HA6F@1150|Oscillatoriales 1117|Cyanobacteria S Peptidase_C39 like family - - - - - - - - - - - - Peptidase_C39_2 SJTD3_k127_1018429_2 316274.Haur_0626 2.467e-31 130.0 COG1309@1|root,COG1309@2|Bacteria,2G8XR@200795|Chloroflexi,377W5@32061|Chloroflexia 32061|Chloroflexia K PFAM regulatory protein TetR - - - - - - - - - - - - TetR_N SJTD3_k127_1018429_1 1131269.AQVV01000004_gene636 1.894e-55 218.0 COG3221@1|root,COG3221@2|Bacteria 2|Bacteria P organic phosphonate transport phnD - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd SJTD3_k127_1018429_0 357808.RoseRS_2358 5.952e-69 259.0 COG1525@1|root,COG1572@1|root,COG1525@2|Bacteria,COG1572@2|Bacteria,2G86R@200795|Chloroflexi,3757A@32061|Chloroflexia 32061|Chloroflexia G PFAM peptidase domain protein - - - - - - - - - - - - NPCBM_assoc,PPC SJTD3_k127_1019386_2 756067.MicvaDRAFT_3232 9.596e-25 107.0 COG0500@1|root,COG2226@2|Bacteria,1G4RI@1117|Cyanobacteria,1HF5F@1150|Oscillatoriales 1117|Cyanobacteria H PFAM Methyltransferase type 11 - - - - - - - - - - - - - SJTD3_k127_1019386_1 926550.CLDAP_08060 1.306e-87 296.0 COG2003@1|root,COG2003@2|Bacteria,2G6BK@200795|Chloroflexi 200795|Chloroflexi L Belongs to the UPF0758 family - - - ko:K03630 - - - - ko00000 - - - RadC SJTD3_k127_1019386_0 1122182.KB903813_gene2669 7.956e-92 312.0 COG1409@1|root,COG1409@2|Bacteria,2IM97@201174|Actinobacteria,4D9VR@85008|Micromonosporales 201174|Actinobacteria S Calcineurin-like phosphoesterase - - 3.1.3.1 ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - Metallophos SJTD3_k127_1021471_0 926560.KE387023_gene2923 1.974e-48 188.0 COG2866@1|root,COG2866@2|Bacteria,1WMA9@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus M Zn_pept - - - - - - - - - - - - Peptidase_M14 SJTD3_k127_1025829_0 1501230.ET33_07065 2.37e-60 225.0 COG2197@1|root,COG2197@2|Bacteria,1VSKR@1239|Firmicutes,4HUB6@91061|Bacilli,26WVV@186822|Paenibacillaceae 91061|Bacilli KT response regulator - - - - - - - - - - - - - SJTD3_k127_1025829_1 479434.Sthe_2339 3.999e-34 136.0 COG1278@1|root,COG1278@2|Bacteria,2G79W@200795|Chloroflexi,27YHA@189775|Thermomicrobia 189775|Thermomicrobia K Probable zinc-ribbon domain - - - - - - - - - - - - zf-trcl SJTD3_k127_1025829_2 580331.Thit_2267 2.875e-09 59.0 COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,42EKA@68295|Thermoanaerobacterales 186801|Clostridia E PFAM aminotransferase class V - - - - - - - - - - - - Aminotran_5 SJTD3_k127_1026409_0 1382356.JQMP01000003_gene1473 1.868e-160 528.0 COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi,27XN1@189775|Thermomicrobia 189775|Thermomicrobia J DALR anticodon binding domain argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - DALR_1,tRNA-synt_1d SJTD3_k127_1039744_0 383372.Rcas_0740 1.571e-265 837.0 COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,374YB@32061|Chloroflexia 32061|Chloroflexia M PFAM transferase hexapeptide repeat containing protein - - 2.7.7.13,5.4.2.8 ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III SJTD3_k127_1043717_5 1162668.LFE_1678 0.0005221 45.0 COG0457@1|root,COG0457@2|Bacteria 1162668.LFE_1678|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SJTD3_k127_1043717_3 311402.Avi_0012 8.055e-09 63.0 COG1396@1|root,COG1396@2|Bacteria,1N1CT@1224|Proteobacteria,2UCMF@28211|Alphaproteobacteria,4BEU1@82115|Rhizobiaceae 28211|Alphaproteobacteria K transcriptional - - - - - - - - - - - - HTH_3,HTH_31 SJTD3_k127_1043717_4 1203606.HMPREF1526_01742 9.703e-06 55.0 COG2856@1|root,COG2856@2|Bacteria,1V1KH@1239|Firmicutes,24GHH@186801|Clostridia,36VFM@31979|Clostridiaceae 186801|Clostridia E Pfam:DUF955 - - - - - - - - - - - - Peptidase_M78 SJTD3_k127_1043717_2 545693.BMQ_1650 2.008e-27 121.0 COG1051@1|root,COG1051@2|Bacteria,1VJ3C@1239|Firmicutes,4HQHF@91061|Bacilli,1ZIGN@1386|Bacillus 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX SJTD3_k127_1043717_1 383372.Rcas_3242 5.825e-40 157.0 COG1040@1|root,COG1040@2|Bacteria,2G6WB@200795|Chloroflexi,377AQ@32061|Chloroflexia 32061|Chloroflexia S competence protein - - - - - - - - - - - - Pribosyltran SJTD3_k127_1043717_0 1382304.JNIL01000001_gene3015 1.347e-79 268.0 COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,4HAKQ@91061|Bacilli,279ER@186823|Alicyclobacillaceae 91061|Bacilli H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM SJTD3_k127_1067316_0 927677.ALVU02000001_gene2370 7.134e-49 190.0 COG1597@1|root,COG1597@2|Bacteria,1G0MV@1117|Cyanobacteria 1117|Cyanobacteria I PFAM Diacylglycerol kinase, catalytic - - - - - - - - - - - - DAGK_cat SJTD3_k127_1073340_0 234267.Acid_1471 3.946e-56 212.0 COG0491@1|root,COG0491@2|Bacteria,3Y83W@57723|Acidobacteria 57723|Acidobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SJTD3_k127_1073340_2 533247.CRD_00341 8.112e-11 68.0 2EPAC@1|root,329XD@2|Bacteria,1GK94@1117|Cyanobacteria,1HTHE@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - SJTD3_k127_1073340_1 522306.CAP2UW1_0994 2.217e-29 121.0 COG3743@1|root,COG3743@2|Bacteria,1RA3K@1224|Proteobacteria,2VVIG@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4332) - - - - - - - - - - - - DUF4332 SJTD3_k127_1080106_3 118173.KB235914_gene1603 7.664e-39 148.0 COG0028@1|root,COG0028@2|Bacteria,1G0KQ@1117|Cyanobacteria,1H8HU@1150|Oscillatoriales 1117|Cyanobacteria EH Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ilvB - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N SJTD3_k127_1080106_5 1254432.SCE1572_35510 4.385e-10 67.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,42MDU@68525|delta/epsilon subdivisions,2WM9V@28221|Deltaproteobacteria,2YUA7@29|Myxococcales 28221|Deltaproteobacteria C Aldehyde dehydrogenase family gabD - 1.2.1.16,1.2.1.20,1.2.1.79 ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 M00027 R00713,R00714,R02401 RC00080 ko00000,ko00001,ko00002,ko01000 - - - Aldedh SJTD3_k127_1080106_0 525904.Tter_0958 3.308e-88 298.0 COG0217@1|root,COG0217@2|Bacteria,2NNSI@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulatory protein yebC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - - - - - - - - - - Transcrip_reg SJTD3_k127_1080106_2 913865.DOT_1742 1.058e-55 202.0 COG0817@1|root,COG0817@2|Bacteria,1V3N9@1239|Firmicutes,24HMI@186801|Clostridia,261I9@186807|Peptococcaceae 186801|Clostridia L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group ruvC - 3.1.22.4 ko:K01159 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvC SJTD3_k127_1080106_1 326427.Cagg_0318 9.309e-79 271.0 COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,3757F@32061|Chloroflexia 32061|Chloroflexia J PFAM ribosomal RNA methyltransferase RrmJ FtsJ - - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 SJTD3_k127_1080106_4 498761.HM1_0298 1.197e-14 79.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia 186801|Clostridia H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iHN637.CLJU_RS05480 NAD_kinase SJTD3_k127_1080733_0 1173024.KI912151_gene2146 4.661e-198 627.0 COG2312@1|root,COG2312@2|Bacteria,1GA2Z@1117|Cyanobacteria,1JKPG@1189|Stigonemataceae 1117|Cyanobacteria S Erythromycin esterase - - - - - - - - - - - - Erythro_esteras SJTD3_k127_1082976_0 477974.Daud_0851 0.0 1321.0 COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,264Z9@186807|Peptococcaceae 186801|Clostridia G Alpha-amylase domain ams - 2.4.1.4,3.2.1.1,5.4.99.16 ko:K05341,ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R01823,R02108,R02112,R11262 RC00028,RC01816 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase SJTD3_k127_1082976_1 240292.Ava_4664 0.0 1051.0 COG0045@1|root,COG1042@1|root,COG1670@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1670@2|Bacteria,1G2D3@1117|Cyanobacteria,1HIIK@1161|Nostocales 1117|Cyanobacteria CJ TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig SJTD3_k127_1083031_0 880073.Calab_3450 3.697e-96 335.0 COG0587@1|root,COG0587@2|Bacteria,2NNVY@2323|unclassified Bacteria 2|Bacteria L DNA polymerase dnaE-2 - 2.7.7.7 ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP SJTD3_k127_1083031_1 485913.Krac_0472 2.92e-72 248.0 COG1708@1|root,COG1708@2|Bacteria 2|Bacteria S nucleotidyltransferase activity aadD - - ko:K17882 - - - - ko00000,ko01000,ko01504 - - - KNTase_C,NTP_transf_2 SJTD3_k127_1085373_2 485913.Krac_8232 2.326e-23 103.0 COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi 200795|Chloroflexi EGP Transmembrane secretion effector - - - - - - - - - - - - - SJTD3_k127_1085373_3 877418.ATWV01000007_gene2395 2.1e-15 89.0 COG3595@1|root,COG3595@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF4097 SJTD3_k127_1085373_1 1144275.COCOR_01634 1.367e-25 113.0 COG3877@1|root,COG3877@2|Bacteria,1QTDB@1224|Proteobacteria,434C3@68525|delta/epsilon subdivisions,2WZVJ@28221|Deltaproteobacteria,2Z2U6@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function (DUF2089) - - - - - - - - - - - - DUF2089 SJTD3_k127_1085373_0 383372.Rcas_3050 1.529e-40 156.0 COG2071@1|root,COG2071@2|Bacteria,2G6QN@200795|Chloroflexi,375KT@32061|Chloroflexia 32061|Chloroflexia S PFAM glutamine amidotransferase class-I - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 SJTD3_k127_1086415_3 1415774.U728_541 5.198e-09 66.0 29V2B@1|root,30GFG@2|Bacteria,1UFXY@1239|Firmicutes,24KMA@186801|Clostridia,36JHR@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - - SJTD3_k127_1086415_0 1254432.SCE1572_24145 7.017e-223 707.0 COG2373@1|root,COG2373@2|Bacteria,1Q2SN@1224|Proteobacteria 1224|Proteobacteria I Animal haem peroxidase - - - - - - - - - - - - An_peroxidase SJTD3_k127_1086415_1 32057.KB217478_gene5036 5.424e-66 238.0 COG0753@1|root,COG2373@1|root,COG0753@2|Bacteria,COG2373@2|Bacteria,1GQ3G@1117|Cyanobacteria,1HUC4@1161|Nostocales 1117|Cyanobacteria P Animal haem peroxidase - - - - - - - - - - - - An_peroxidase SJTD3_k127_1087097_0 525904.Tter_0255 1.796e-78 274.0 COG0624@1|root,COG0624@2|Bacteria,2NNX2@2323|unclassified Bacteria 2|Bacteria E Peptidase dimerisation domain ygeY - - - - - - - - - - - M20_dimer,Peptidase_M20 SJTD3_k127_1087097_1 861299.J421_4371 1.567e-39 160.0 COG1215@1|root,COG1215@2|Bacteria,1ZU0V@142182|Gemmatimonadetes 142182|Gemmatimonadetes M Glycosyl transferase family 21 - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SJTD3_k127_1087872_4 926550.CLDAP_24770 0.0004207 45.0 COG1070@1|root,COG1070@2|Bacteria 2|Bacteria G xylulokinase activity lyx_2 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 ko:K00848,ko:K00851,ko:K00854,ko:K00862 ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737,R01902,R03014,R11536 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N SJTD3_k127_1087872_3 1223545.GS4_15_00160 7.508e-30 131.0 COG0546@1|root,COG0546@2|Bacteria,2HXG7@201174|Actinobacteria,4GFMH@85026|Gordoniaceae 201174|Actinobacteria S HAD-hyrolase-like - - 3.6.1.1 ko:K06019 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - HAD_2 SJTD3_k127_1087872_1 926550.CLDAP_29710 2.229e-81 281.0 COG1735@1|root,COG1735@2|Bacteria,2G8Y3@200795|Chloroflexi 200795|Chloroflexi S Phosphotriesterase family - - - ko:K07048 - - - - ko00000 - - - PTE SJTD3_k127_1087872_2 1343740.M271_42385 1.924e-50 192.0 COG1414@1|root,COG1414@2|Bacteria,2IMT9@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - HTH_IclR,IclR SJTD3_k127_1087872_0 357808.RoseRS_3490 8.01e-209 658.0 COG1012@1|root,COG1012@2|Bacteria,2G5NY@200795|Chloroflexi 200795|Chloroflexi C Aldehyde dehydrogenase - - - - - - - - - - - - Aldedh SJTD3_k127_1094413_0 765420.OSCT_2657 1.243e-140 466.0 COG0608@1|root,COG0608@2|Bacteria,2G5US@200795|Chloroflexi,374UZ@32061|Chloroflexia 32061|Chloroflexia L PFAM phosphoesterase, RecJ domain protein - - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 SJTD3_k127_1094413_2 316067.Geob_2623 4.021e-10 71.0 COG3884@1|root,COG3884@2|Bacteria,1MYEN@1224|Proteobacteria,42STQ@68525|delta/epsilon subdivisions,2WPV7@28221|Deltaproteobacteria 28221|Deltaproteobacteria I Acyl-ACP thioesterase - - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE SJTD3_k127_1094413_3 1122182.KB903838_gene4117 0.0001807 53.0 2DHV8@1|root,30127@2|Bacteria,2GU8T@201174|Actinobacteria,4DG03@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_1094413_1 1048983.EL17_04825 8.888e-19 93.0 COG0500@1|root,COG0500@2|Bacteria,4PPBM@976|Bacteroidetes 976|Bacteroidetes Q Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_25 SJTD3_k127_1112543_1 350688.Clos_1058 9.128e-75 274.0 COG0421@1|root,COG0421@2|Bacteria,1VRGK@1239|Firmicutes,24C37@186801|Clostridia,36RCA@31979|Clostridiaceae 186801|Clostridia E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth SJTD3_k127_1112543_0 211114.JOEF01000011_gene5186 9.018e-164 522.0 COG4733@1|root,COG4733@2|Bacteria,2I3TX@201174|Actinobacteria,4DYI4@85010|Pseudonocardiales 201174|Actinobacteria S Protein of unknown function (DUF2961) - - - - - - - - - - - - DUF2961 SJTD3_k127_1112543_2 1120949.KB903313_gene494 1.101e-10 63.0 COG0251@1|root,COG0251@2|Bacteria,2GQ40@201174|Actinobacteria 201174|Actinobacteria J YjgF/chorismate_mutase-like, putative endoribonuclease - - - - - - - - - - - - YjgF_endoribonc SJTD3_k127_1112572_7 671143.DAMO_0647 2.805e-10 62.0 COG2025@1|root,COG2025@2|Bacteria,2NNR6@2323|unclassified Bacteria 2|Bacteria C Electron transfer flavoprotein etfA-5 - - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha SJTD3_k127_1112572_3 211165.AJLN01000141_gene2398 1.409e-50 182.0 COG1145@1|root,32UJ7@2|Bacteria,1G9Q2@1117|Cyanobacteria 1117|Cyanobacteria C Ferredoxin - - - - - - - - - - - - - SJTD3_k127_1112572_6 525904.Tter_0505 1.081e-29 124.0 COG0265@1|root,COG0695@1|root,COG0265@2|Bacteria,COG0695@2|Bacteria,2NQ8T@2323|unclassified Bacteria 2|Bacteria O Glutaredoxin grxC - 3.4.21.107 ko:K03676,ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - Glutaredoxin,PDZ_2 SJTD3_k127_1112572_0 1183377.Py04_0738 3.751e-114 378.0 COG0448@1|root,arCOG00912@2157|Archaea,2XTI4@28890|Euryarchaeota,242ZT@183968|Thermococci 183968|Thermococci E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N SJTD3_k127_1112572_1 246969.TAM4_1238 8.185e-104 347.0 COG0549@1|root,arCOG00863@2157|Archaea,2XTCB@28890|Euryarchaeota,243F1@183968|Thermococci 183968|Thermococci E Belongs to the carbamate kinase family cpkA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 - R00150,R01395 RC00002,RC00043,RC02803,RC02804 ko00000,ko00001,ko01000 - - - AA_kinase SJTD3_k127_1112572_4 1500894.JQNN01000001_gene1358 5.189e-47 173.0 COG0662@1|root,COG0662@2|Bacteria,1RJ7D@1224|Proteobacteria,2VU1R@28216|Betaproteobacteria 28216|Betaproteobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_1112572_5 1166018.FAES_5179 2.497e-31 124.0 2EJF2@1|root,32Z95@2|Bacteria,4P5WW@976|Bacteroidetes,47VU2@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - SJTD3_k127_1112572_2 234267.Acid_0349 5.101e-59 209.0 COG0438@1|root,COG1232@1|root,COG0438@2|Bacteria,COG1232@2|Bacteria 2|Bacteria H protoporphyrinogen oxidase activity tuaH - 5.4.99.9 ko:K01854,ko:K07011 ko00052,ko00520,map00052,map00520 - R00505,R09009 RC00317,RC02396 ko00000,ko00001,ko01000 - - - Amino_oxidase,GLF,Glyco_trans_1_4,NAD_binding_8 SJTD3_k127_1120584_1 292459.STH1313 1.936e-71 244.0 COG0395@1|root,COG0395@2|Bacteria,1UY7D@1239|Firmicutes,25C4X@186801|Clostridia 186801|Clostridia P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SJTD3_k127_1120584_0 525904.Tter_2118 1.241e-103 365.0 COG3408@1|root,COG3408@2|Bacteria 2|Bacteria G Glycogen debranching enzyme hypBA2 - - - - - - - - - - - BNR_2,Bac_rhamnosid6H,F5_F8_type_C,GDE_C,RicinB_lectin_2,Trehalase SJTD3_k127_1120584_2 1341151.ASZU01000026_gene1121 1.146e-25 109.0 COG2076@1|root,COG2076@2|Bacteria,1VEUF@1239|Firmicutes,4HNJX@91061|Bacilli,27CGE@186824|Thermoactinomycetaceae 91061|Bacilli P Small Multidrug Resistance protein qacC - - ko:K03297,ko:K11814 - M00710 - - ko00000,ko00002,ko02000 2.A.7.1,2.A.7.1.6 - - Multi_Drug_Res SJTD3_k127_1122745_1 1128421.JAGA01000002_gene1351 2.289e-58 207.0 COG0438@1|root,COG0438@2|Bacteria,2NQ17@2323|unclassified Bacteria 2|Bacteria M glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_1122745_2 926560.KE387023_gene3676 5.575e-10 66.0 COG2010@1|root,COG2010@2|Bacteria,1WN3Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrome_CBB3 SJTD3_k127_1122745_0 525904.Tter_0977 3.553e-140 460.0 COG0060@1|root,COG0060@2|Bacteria,2NNT5@2323|unclassified Bacteria 2|Bacteria J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iG2583_1286.G2583_0027,iPC815.YPO0475 Anticodon_1,tRNA-synt_1,zf-FPG_IleRS SJTD3_k127_1127923_1 1173027.Mic7113_1472 3.947e-111 376.0 COG3349@1|root,COG3349@2|Bacteria,1G09Q@1117|Cyanobacteria,1H81V@1150|Oscillatoriales 1117|Cyanobacteria S Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' crtQ - 1.3.5.6 ko:K00514 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R04798,R04800,R07511,R09656,R09658 RC01214,RC01959 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase SJTD3_k127_1127923_0 1128421.JAGA01000003_gene3172 3.782e-123 411.0 COG0644@1|root,COG0644@2|Bacteria 2|Bacteria C geranylgeranyl reductase activity - - 1.14.19.9 ko:K14266 ko00404,ko01130,map00404,map01130 M00789,M00790 R09570 RC00949 ko00000,ko00001,ko00002,ko01000 - - - MDMPI_N,Trp_halogenase SJTD3_k127_1131337_0 518766.Rmar_1549 1.953e-110 374.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FIUV@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes C dehydrogenase, E1 component bfmBAB - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C SJTD3_k127_1131337_1 351160.RCIX653 4.311e-16 84.0 COG0477@1|root,arCOG00130@2157|Archaea,2XX8J@28890|Euryarchaeota,2NB8J@224756|Methanomicrobia 224756|Methanomicrobia G Major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1,MFS_1_like SJTD3_k127_1133324_0 518766.Rmar_1774 4.086e-52 201.0 COG1626@1|root,COG1626@2|Bacteria,4PKJT@976|Bacteroidetes 976|Bacteroidetes G glycoside hydrolase family 37 - - - - - - - - - - - - Glyco_hydro_63,Trehalase SJTD3_k127_1133324_1 1122223.KB890696_gene262 6.026e-46 172.0 COG1653@1|root,COG1653@2|Bacteria,1WJ53@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 SJTD3_k127_1133592_0 479434.Sthe_1974 2.2e-187 599.0 COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia 189775|Thermomicrobia J Elongation factor SelB, winged helix - - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 SJTD3_k127_1133592_3 1128421.JAGA01000002_gene1694 6.238e-42 165.0 COG2176@1|root,COG2378@1|root,COG2176@2|Bacteria,COG2378@2|Bacteria 2|Bacteria K regulation of single-species biofilm formation dnaQ - 2.7.7.7 ko:K02342,ko:K03763,ko:K13573 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03051,ko03400 - - - GIY-YIG,RNase_T,VRR_NUC,WYL SJTD3_k127_1133592_4 537013.CLOSTMETH_03873 3.349e-07 62.0 COG0640@1|root,COG0640@2|Bacteria,1V2A1@1239|Firmicutes,24RXK@186801|Clostridia,3WQFF@541000|Ruminococcaceae 186801|Clostridia K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_5 SJTD3_k127_1133592_2 926560.KE387027_gene1085 5.43e-49 177.0 COG0251@1|root,COG0251@2|Bacteria,1WKNH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus J Endoribonuclease L-PSP - - - - - - - - - - - - Ribonuc_L-PSP SJTD3_k127_1133592_1 485913.Krac_2030 4.604e-75 259.0 COG2197@1|root,COG2197@2|Bacteria,2G6K1@200795|Chloroflexi 2|Bacteria K Two component transcriptional regulator, LuxR family - - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg SJTD3_k127_1138709_0 1210884.HG799464_gene10582 2.158e-202 645.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity mtsE - - ko:K11089 ko05322,map05322 - - - ko00000,ko00001 - - - TROVE,VWA_2 SJTD3_k127_1138709_1 525904.Tter_0978 3.35e-63 221.0 COG1403@1|root,COG1403@2|Bacteria,2NPJD@2323|unclassified Bacteria 2|Bacteria L HNH endonuclease MA20_20605 - - - - - - - - - - - HNH,HNH_5 SJTD3_k127_1138709_2 479434.Sthe_0104 4.03e-39 150.0 COG4447@1|root,COG4447@2|Bacteria,2G8DW@200795|Chloroflexi,27YX3@189775|Thermomicrobia 189775|Thermomicrobia S cellulose binding - - - - - - - - - - - - - SJTD3_k127_1143142_1 2002.JOEQ01000016_gene7347 1.004e-137 475.0 COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales 201174|Actinobacteria M WD40 repeats - - - - - - - - - - - - HTH_31,WD40 SJTD3_k127_1143142_2 497964.CfE428DRAFT_0631 1.58e-60 239.0 COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia 74201|Verrucomicrobia T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,NB-ARC SJTD3_k127_1143142_4 1123504.JQKD01000102_gene3524 0.0006429 45.0 2CC4J@1|root,2Z7W8@2|Bacteria,1R42M@1224|Proteobacteria,2VN58@28216|Betaproteobacteria,4ADD2@80864|Comamonadaceae 28216|Betaproteobacteria S Domain of unknown function (DUF932) - - - - - - - - - - - - DUF932 SJTD3_k127_1143142_0 649638.Trad_2634 2.542e-167 541.0 COG0702@1|root,COG0702@2|Bacteria,1WJH3@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus GM Protein of unknown function (DUF2867) - - - - - - - - - - - - DUF2867,NAD_binding_10,NmrA SJTD3_k127_1143142_3 383372.Rcas_3982 3.428e-13 75.0 COG3467@1|root,COG3467@2|Bacteria,2G77X@200795|Chloroflexi 200795|Chloroflexi S PFAM pyridoxamine 5'-phosphate oxidase-related - - - - - - - - - - - - Putative_PNPOx SJTD3_k127_1150456_1 357808.RoseRS_0609 9.305e-86 293.0 COG1477@1|root,COG1477@2|Bacteria,2G6WH@200795|Chloroflexi,375JB@32061|Chloroflexia 32061|Chloroflexia H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE SJTD3_k127_1150456_2 383372.Rcas_0225 5.339e-75 263.0 COG4097@1|root,COG4097@2|Bacteria,2G71Y@200795|Chloroflexi,375FI@32061|Chloroflexia 32061|Chloroflexia P Ferric reductase like transmembrane component - - - - - - - - - - - - Ferric_reduct SJTD3_k127_1150456_3 1254432.SCE1572_31350 3.177e-21 100.0 COG1695@1|root,COG1695@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - DUF4180,PadR SJTD3_k127_1150456_0 1121324.CLIT_10c01870 7.456e-131 436.0 COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia 186801|Clostridia V Psort location Cytoplasmic, score - - - - - - - - - - - - Beta-lactamase SJTD3_k127_1150456_4 192952.MM_0566 0.0003118 51.0 COG4912@1|root,arCOG05122@2157|Archaea,2XWYV@28890|Euryarchaeota,2N9IE@224756|Methanomicrobia 224756|Methanomicrobia L PFAM DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation SJTD3_k127_1161617_3 1303518.CCALI_01089 1.075e-30 138.0 COG2211@1|root,COG2211@2|Bacteria 2|Bacteria G Major facilitator Superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_1161617_0 479432.Sros_4136 8.251e-121 394.0 COG0596@1|root,COG0596@2|Bacteria,2I9PQ@201174|Actinobacteria,4EHNW@85012|Streptosporangiales 201174|Actinobacteria S Alpha beta hydrolase - - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_1161617_2 485913.Krac_5861 3.255e-33 134.0 COG2947@1|root,COG2947@2|Bacteria 2|Bacteria L Ubiquinol--cytochrome c reductase - - - ko:K07452 - - - - ko00000,ko01000,ko02048 - - - AAA_5,EVE,HNH SJTD3_k127_1161617_1 479434.Sthe_0159 8.158e-67 238.0 COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,2G7US@200795|Chloroflexi,27YN6@189775|Thermomicrobia 189775|Thermomicrobia L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - AAA_11,AAA_12,PDDEXK_1 SJTD3_k127_1171445_1 525904.Tter_2599 1.963e-26 112.0 COG0451@1|root,COG0451@2|Bacteria,2NPZU@2323|unclassified Bacteria 2|Bacteria M Male sterility protein - - 1.1.1.219,5.1.3.26 ko:K00091,ko:K19997 - - - - ko00000,ko01000 - - - Epimerase SJTD3_k127_1171445_0 1173026.Glo7428_0555 2.62e-180 594.0 COG2203@1|root,COG3322@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3322@2|Bacteria,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria 1117|Cyanobacteria T signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - - - - - - - - - - CHASE4,EAL,GGDEF,PAS,PAS_4 SJTD3_k127_1173633_1 1120949.KB903303_gene6761 8.407e-70 242.0 COG0500@1|root,COG2226@2|Bacteria,2GNTH@201174|Actinobacteria,4D8MM@85008|Micromonosporales 201174|Actinobacteria Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SJTD3_k127_1173633_0 1128421.JAGA01000002_gene104 3.762e-92 316.0 COG0598@1|root,COG0598@2|Bacteria,2NQIW@2323|unclassified Bacteria 2|Bacteria P CorA-like Mg2+ transporter protein corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA SJTD3_k127_1173633_6 1120950.KB892762_gene5505 0.0003097 51.0 2D17X@1|root,32TA2@2|Bacteria,2GY4U@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_1173633_3 926550.CLDAP_25450 4.725e-47 186.0 COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi 2|Bacteria D PFAM cell divisionFtsK SpoIIIE ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma SJTD3_k127_1173633_5 485913.Krac_3647 3.435e-06 55.0 COG4283@1|root,COG4283@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1706) M1-431 - - - - - - - - - - - DUF1706 SJTD3_k127_1173633_4 243231.GSU0041 1.212e-13 80.0 COG1974@1|root,COG1974@2|Bacteria,1MW80@1224|Proteobacteria,42URP@68525|delta/epsilon subdivisions,2WQFZ@28221|Deltaproteobacteria,43UTN@69541|Desulfuromonadales 28221|Deltaproteobacteria K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 SJTD3_k127_1173633_2 309801.trd_0666 4.087e-58 211.0 COG1974@1|root,COG1974@2|Bacteria,2G6NC@200795|Chloroflexi,27Y6E@189775|Thermomicrobia 189775|Thermomicrobia K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair lexA - 3.4.21.88 ko:K01356 - M00729 - - ko00000,ko00002,ko01000,ko01002,ko03400 - - - LexA_DNA_bind,Peptidase_S24 SJTD3_k127_1195971_0 1329516.JPST01000012_gene180 4.279e-274 855.0 COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,4H9NH@91061|Bacilli,27BE2@186824|Thermoactinomycetaceae 91061|Bacilli E Urocanase C-terminal domain hutU - 4.2.1.49 ko:K01712 ko00340,ko01100,map00340,map01100 M00045 R02914 RC00804 ko00000,ko00001,ko00002,ko01000 - - - Urocanase,Urocanase_C,Urocanase_N SJTD3_k127_1195971_1 485913.Krac_9334 5.303e-64 230.0 COG0637@1|root,COG0637@2|Bacteria 2|Bacteria S phosphonoacetaldehyde hydrolase activity - - - ko:K07025 - - - - ko00000 - - - HAD_2,Hydrolase SJTD3_k127_1195971_2 1173027.Mic7113_2082 1.023e-47 184.0 COG0454@1|root,COG0456@2|Bacteria,1G407@1117|Cyanobacteria,1H9GX@1150|Oscillatoriales 1117|Cyanobacteria K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_1195971_3 179408.Osc7112_0397 6.886e-42 171.0 COG0454@1|root,COG0456@2|Bacteria,1G407@1117|Cyanobacteria,1H9GX@1150|Oscillatoriales 1117|Cyanobacteria K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_1198629_1 1121929.KB898671_gene4132 3.564e-45 173.0 COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,4H9QE@91061|Bacilli 91061|Bacilli C glycerophosphoryl diester phosphodiesterase glpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD SJTD3_k127_1198629_0 479434.Sthe_1444 2.417e-49 182.0 COG0560@1|root,COG0560@2|Bacteria 2|Bacteria E Phosphoserine phosphatase serB1 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 2.3.1.51,3.1.3.3 ko:K15781,ko:K21830 - - - - ko00000,ko01000 - - - Acyltransferase,HAD SJTD3_k127_1220772_0 572544.Ilyop_1757 6.114e-52 196.0 COG0162@1|root,COG0162@2|Bacteria,378M9@32066|Fusobacteria 32066|Fusobacteria J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b SJTD3_k127_1220772_4 1267533.KB906735_gene4802 4.804e-07 57.0 2DB97@1|root,32TX2@2|Bacteria,3Y59S@57723|Acidobacteria,2JJUG@204432|Acidobacteriia 204432|Acidobacteriia - - - - - - - - - - - - - - - SJTD3_k127_1220772_3 909613.UO65_0956 1.213e-07 62.0 COG0454@1|root,COG0456@2|Bacteria,2HJGF@201174|Actinobacteria,4E0PN@85010|Pseudonocardiales 201174|Actinobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 SJTD3_k127_1220772_1 485913.Krac_2664 1.283e-51 196.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_1220772_2 1194165.CAJF01000023_gene3176 1.704e-20 96.0 2DMMA@1|root,32SDH@2|Bacteria,2HZ6N@201174|Actinobacteria,4FSGP@85023|Microbacteriaceae 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_122887_7 485913.Krac_8332 7.689e-10 66.0 COG3372@1|root,COG3372@2|Bacteria,2G9BS@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF790) - - - ko:K09744 - - - - ko00000 - - - DUF790 SJTD3_k127_122887_4 1122622.ATWJ01000007_gene2022 9.787e-73 255.0 COG0702@1|root,COG0702@2|Bacteria,2ICEY@201174|Actinobacteria,4FHR4@85021|Intrasporangiaceae 201174|Actinobacteria GM NmrA-like family - - - - - - - - - - - - NAD_binding_10,NmrA SJTD3_k127_122887_6 42256.RradSPS_0710 3.638e-11 74.0 2D0CU@1|root,33KYC@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_122887_3 525904.Tter_0012 2.322e-88 301.0 COG1028@1|root,COG1028@2|Bacteria,2NP35@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SJTD3_k127_122887_2 525904.Tter_0013 2.214e-102 342.0 COG0331@1|root,COG0331@2|Bacteria,2NP3V@2323|unclassified Bacteria 2|Bacteria I malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 SJTD3_k127_122887_0 471223.GWCH70_0750 1.313e-142 464.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1WE7S@129337|Geobacillus 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458,ko:K14660 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - iSB619.SA_RS04785 Ketoacyl-synt_C,ketoacyl-synt SJTD3_k127_122887_1 309801.trd_A0447 2.205e-137 449.0 COG0304@1|root,COG0304@2|Bacteria,2G5K7@200795|Chloroflexi,27Y13@189775|Thermomicrobia 189775|Thermomicrobia I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt SJTD3_k127_122887_5 485913.Krac_9072 7.235e-56 202.0 COG3214@1|root,COG3214@2|Bacteria,2G766@200795|Chloroflexi 200795|Chloroflexi S Winged helix DNA-binding domain - - - - - - - - - - - - HTH_42 SJTD3_k127_1229555_0 1336208.JADY01000001_gene887 1.261e-130 424.0 COG0473@1|root,COG0473@2|Bacteria,1MUH4@1224|Proteobacteria,2TSBB@28211|Alphaproteobacteria,2JVIE@204441|Rhodospirillales 204441|Rhodospirillales CE Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - - Iso_dh SJTD3_k127_1229555_1 1128421.JAGA01000001_gene2318 5.891e-22 98.0 COG0395@1|root,COG0395@2|Bacteria,2NPII@2323|unclassified Bacteria 2|Bacteria G PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SJTD3_k127_1235285_0 570268.ANBB01000008_gene4700 7.069e-234 738.0 COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4EH1A@85012|Streptosporangiales 2|Bacteria L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran SJTD3_k127_1238061_1 316067.Geob_1230 2.863e-10 62.0 COG1826@1|root,COG1826@2|Bacteria,1NGDP@1224|Proteobacteria,42V5P@68525|delta/epsilon subdivisions,2WRM0@28221|Deltaproteobacteria,43VPN@69541|Desulfuromonadales 28221|Deltaproteobacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 SJTD3_k127_1238061_0 1267534.KB906756_gene662 2.168e-91 320.0 COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria 2|Bacteria K ADP binding - - - - - - - - - - - - AAA_22,DUF4062,NB-ARC,TPR_12,TPR_19,TPR_8,Trans_reg_C SJTD3_k127_1238339_1 1410618.JNKI01000031_gene2179 2.275e-09 67.0 COG3261@1|root,COG3262@1|root,COG3261@2|Bacteria,COG3262@2|Bacteria,1VZGX@1239|Firmicutes,4H3CA@909932|Negativicutes 909932|Negativicutes C NADH dehydrogenase - - - - - - - - - - - - Complex1_30kDa,Complex1_49kDa,NiFeSe_Hases SJTD3_k127_1238339_0 1382306.JNIM01000001_gene522 2.828e-41 160.0 COG0438@1|root,COG0438@2|Bacteria,2G7W6@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_1243872_2 768706.Desor_3920 1.165e-54 199.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,260XG@186807|Peptococcaceae 186801|Clostridia J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey SJTD3_k127_1243872_0 525904.Tter_0805 3.46e-176 561.0 COG0334@1|root,COG0334@2|Bacteria,2NNRJ@2323|unclassified Bacteria 2|Bacteria E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N SJTD3_k127_1243872_1 525904.Tter_1683 1.452e-78 276.0 COG0515@1|root,COG3103@1|root,COG0515@2|Bacteria,COG4991@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K07282,ko:K12132,ko:K15539 - - - - ko00000,ko01000,ko01001 - - - Pkinase,SH3_3,SH3_4 SJTD3_k127_1249307_2 867845.KI911784_gene1691 1.418e-62 219.0 COG0484@1|root,COG0484@2|Bacteria,2G5NV@200795|Chloroflexi,374VC@32061|Chloroflexia 32061|Chloroflexia O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG SJTD3_k127_1249307_6 644282.Deba_2282 1.005e-11 70.0 COG1950@1|root,COG1950@2|Bacteria,1N1DF@1224|Proteobacteria,42WCF@68525|delta/epsilon subdivisions,2WRES@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM Membrane protein of - - - ko:K08972 - - - - ko00000 - - - Phage_holin_4_2 SJTD3_k127_1249307_3 383372.Rcas_0523 4.096e-60 221.0 COG0346@1|root,COG0346@2|Bacteria,2G8K0@200795|Chloroflexi,37776@32061|Chloroflexia 32061|Chloroflexia E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase_3 SJTD3_k127_1249307_4 1232410.KI421418_gene2221 2.244e-38 151.0 COG0662@1|root,COG0662@2|Bacteria,1RHRM@1224|Proteobacteria,42UA5@68525|delta/epsilon subdivisions,2WQWH@28221|Deltaproteobacteria,43SMP@69541|Desulfuromonadales 28221|Deltaproteobacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - - SJTD3_k127_1249307_5 1127134.NOCYR_1764 2.282e-18 93.0 2ER8X@1|root,33IUI@2|Bacteria,2IRAS@201174|Actinobacteria,4G57Q@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - NIPSNAP SJTD3_k127_1249307_0 471852.Tcur_1068 5.712e-114 383.0 COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4ENXQ@85012|Streptosporangiales 201174|Actinobacteria S Bacterial low temperature requirement A protein (LtrA) - - - - - - - - - - - - LtrA SJTD3_k127_1249307_1 1121472.AQWN01000008_gene1860 2.687e-67 241.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,260MP@186807|Peptococcaceae 186801|Clostridia K Belongs to the ParB family spo0J - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc SJTD3_k127_125544_9 383372.Rcas_4283 2.652e-32 132.0 COG0319@1|root,COG0319@2|Bacteria,2G78D@200795|Chloroflexi,375VQ@32061|Chloroflexia 32061|Chloroflexia J Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 SJTD3_k127_125544_10 395961.Cyan7425_4493 2.865e-24 110.0 COG0818@1|root,COG0818@2|Bacteria,1G6IC@1117|Cyanobacteria,3KI1I@43988|Cyanothece 1117|Cyanobacteria M Diacylglycerol kinase dgkA - 2.7.1.107 ko:K00901 ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_prokar SJTD3_k127_125544_5 1200792.AKYF01000013_gene4276 7.592e-54 201.0 COG0702@1|root,COG0702@2|Bacteria,1TT3N@1239|Firmicutes,4HB09@91061|Bacilli,26W1M@186822|Paenibacillaceae 91061|Bacilli GM NAD(P)H-binding - - 1.6.5.3,1.6.99.3 ko:K00329,ko:K00356 ko00190,map00190 - R11945 RC00061 ko00000,ko00001,ko01000 - - - NAD_binding_10 SJTD3_k127_125544_8 373994.Riv7116_0120 7.897e-34 134.0 COG3118@1|root,COG3118@2|Bacteria,1G6KZ@1117|Cyanobacteria,1HNFW@1161|Nostocales 1117|Cyanobacteria O Belongs to the thioredoxin family trxA GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin SJTD3_k127_125544_4 383372.Rcas_2690 1.512e-57 228.0 COG0741@1|root,COG1729@1|root,COG0741@2|Bacteria,COG1729@2|Bacteria,2G6NM@200795|Chloroflexi,374VP@32061|Chloroflexia 32061|Chloroflexia M Lytic transglycosylase catalytic - - - ko:K08309 - - - - ko00000,ko01000,ko01011 - GH23 - SLT,TPR_16 SJTD3_k127_125544_6 1205680.CAKO01000032_gene2111 3.676e-48 181.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity lipJ - - - - - - - - - - - Abhydrolase_1,BTAD,GerE,Guanylate_cyc,Hydrolase_4,Trans_reg_C SJTD3_k127_125544_0 32057.KB217478_gene5481 3.352e-134 439.0 COG0477@1|root,COG2814@2|Bacteria,1G2WB@1117|Cyanobacteria 1117|Cyanobacteria EGP PFAM Major Facilitator Superfamily - - - ko:K08223 - - - - ko00000,ko02000 2.A.1.35 - - MFS_1 SJTD3_k127_125544_2 1027396.LMOSA_18710 1.556e-126 407.0 COG0842@1|root,COG0842@2|Bacteria,1TS7U@1239|Firmicutes,4HA36@91061|Bacilli,26KE8@186820|Listeriaceae 91061|Bacilli V Transport permease protein drrB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane SJTD3_k127_125544_1 1122918.KB907285_gene1870 1.9e-133 429.0 COG1131@1|root,COG1131@2|Bacteria,1TPJE@1239|Firmicutes,4HB5U@91061|Bacilli,26SG2@186822|Paenibacillaceae 91061|Bacilli V ABC transporter drrA_1 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162,SRP54 SJTD3_k127_125544_7 1120746.CCNL01000014_gene2125 4.296e-44 163.0 COG4817@1|root,COG4817@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1048) - - - - - - - - - - - - DUF1048 SJTD3_k127_125544_3 1007103.AFHW01000119_gene1268 7.313e-58 203.0 COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,4HIP5@91061|Bacilli,26XR1@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator - - - ko:K10947 - - - - ko00000,ko03000 - - - PadR SJTD3_k127_125544_11 309801.trd_1371 8.145e-14 72.0 COG1376@1|root,COG1376@2|Bacteria,2G8JH@200795|Chloroflexi,27XUR@189775|Thermomicrobia 189775|Thermomicrobia S PFAM ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD SJTD3_k127_1256001_2 1169161.KB897722_gene4346 9.743e-26 111.0 COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria 201174|Actinobacteria I PFAM Phospholipid glycerol acyltransferase - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase SJTD3_k127_1256001_3 1524467.IV04_13700 6.562e-21 101.0 COG0558@1|root,COG0558@2|Bacteria,1RE0I@1224|Proteobacteria,1S2UQ@1236|Gammaproteobacteria,402GQ@613|Serratia 1236|Gammaproteobacteria I CDP-alcohol phosphatidyltransferase ynbA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf SJTD3_k127_1256001_1 1423775.BAMN01000006_gene985 4.9e-28 125.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli,3FC0H@33958|Lactobacillaceae 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 SJTD3_k127_1256001_0 67267.JNXT01000090_gene5369 6.858e-76 263.0 COG2267@1|root,COG2267@2|Bacteria,2I9H2@201174|Actinobacteria 201174|Actinobacteria I Putative methyltransferase - - - - - - - - - - - - Methyltransf_20 SJTD3_k127_1261856_0 485913.Krac_2926 2.453e-129 444.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulator, LuxR family - - - - - - - - - - - - AAA_22,GerE,NB-ARC,TPR_12 SJTD3_k127_1261856_1 1123073.KB899242_gene1520 2.495e-19 96.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - 4.4.1.3,5.3.3.19 ko:K16953,ko:K19547 ko00920,ko01130,map00920,map01130 M00787 R02574 RC00747,RC00748 ko00000,ko00001,ko00002,ko01000 - - - Asp_Arg_Hydrox,Cupin_1,Cupin_2 SJTD3_k127_1263823_7 479434.Sthe_3135 5.669e-88 308.0 COG1721@1|root,COG1721@2|Bacteria,2G6Y7@200795|Chloroflexi,27Y3Z@189775|Thermomicrobia 189775|Thermomicrobia S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 SJTD3_k127_1263823_4 485913.Krac_8718 5.864e-122 400.0 COG0714@1|root,COG0714@2|Bacteria,2G669@200795|Chloroflexi 200795|Chloroflexi S ATPase associated with various cellular activities, AAA_3 - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SJTD3_k127_1263823_3 479434.Sthe_0827 1.029e-126 443.0 COG0613@1|root,COG2865@1|root,COG0613@2|Bacteria,COG2865@2|Bacteria,2G5UU@200795|Chloroflexi 200795|Chloroflexi K SMART phosphoesterase PHP domain protein - - - - - - - - - - - - AlbA_2,PHP SJTD3_k127_1263823_0 1121428.DESHY_120029___1 2.044e-247 791.0 COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,260BY@186807|Peptococcaceae 186801|Clostridia O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner lon - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C SJTD3_k127_1263823_5 1128421.JAGA01000002_gene1035 2.048e-117 393.0 COG0303@1|root,COG0303@2|Bacteria,2NP4N@2323|unclassified Bacteria 2|Bacteria H MoeA N-terminal region (domain I and II) moeA - 2.10.1.1 ko:K03750 ko00790,ko01100,map00790,map01100 - R09735 RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N SJTD3_k127_1263823_6 765420.OSCT_2799 1.541e-114 383.0 COG5282@1|root,COG5282@2|Bacteria,2G800@200795|Chloroflexi,3758B@32061|Chloroflexia 32061|Chloroflexia S Zincin-like metallopeptidase - - - - - - - - - - - - Zincin_2 SJTD3_k127_1263823_10 479434.Sthe_0127 1.906e-30 128.0 COG0526@1|root,COG0526@2|Bacteria,2G8YT@200795|Chloroflexi,27YFH@189775|Thermomicrobia 200795|Chloroflexi CO Thioredoxin - - - - - - - - - - - - Thioredoxin_9 SJTD3_k127_1263823_1 525904.Tter_2737 2.849e-176 559.0 COG0626@1|root,COG0626@2|Bacteria,2NNNS@2323|unclassified Bacteria 2|Bacteria E Cys/Met metabolism PLP-dependent enzyme - - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.2,4.4.1.8 ko:K01739,ko:K01760,ko:K01761,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017,M00609 R00654,R00782,R00999,R01001,R01283,R01286,R01288,R02408,R02508,R03217,R03260,R04770,R04941,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00196,RC00348,RC00382,RC00420,RC00487,RC00488,RC00710,RC01209,RC01210,RC01245,RC02303,RC02814,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP SJTD3_k127_1263823_9 1123321.KB905815_gene3079 2.091e-36 142.0 COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria 201174|Actinobacteria H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine panD - 4.1.1.11 ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R00489 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Asp_decarbox SJTD3_k127_1263823_2 485913.Krac_5186 1.179e-129 418.0 COG1397@1|root,COG1397@2|Bacteria 2|Bacteria O ADP-ribosylglycohydrolase - - - - - - - - - - - - ADP_ribosyl_GH SJTD3_k127_1263823_8 1121468.AUBR01000004_gene173 2.099e-62 233.0 COG2203@1|root,COG3437@1|root,COG4191@1|root,COG2203@2|Bacteria,COG3437@2|Bacteria,COG4191@2|Bacteria,1V7YT@1239|Firmicutes,25ET2@186801|Clostridia,42J5U@68295|Thermoanaerobacterales 186801|Clostridia KT HD domain - - - - - - - - - - - - HD_5 SJTD3_k127_1265658_5 479434.Sthe_1974 9.178e-24 102.0 COG3276@1|root,COG3276@2|Bacteria,2G5JX@200795|Chloroflexi,27XRW@189775|Thermomicrobia 189775|Thermomicrobia J Elongation factor SelB, winged helix - - - ko:K03833 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,SelB-wing_2,SelB-wing_3 SJTD3_k127_1265658_0 671143.DAMO_2491 1.132e-82 286.0 COG1028@1|root,COG1028@2|Bacteria,2NQBD@2323|unclassified Bacteria 2|Bacteria IQ NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - - - - - - - - - - adh_short_C2 SJTD3_k127_1265658_1 47839.CCAU010000004_gene892 2.954e-53 197.0 COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae 201174|Actinobacteria T guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc SJTD3_k127_1265658_2 216594.MMAR_0935 2.176e-50 190.0 COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae 201174|Actinobacteria T guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc SJTD3_k127_1265658_4 1034347.CAHJ01000054_gene133 2.574e-28 125.0 COG0526@1|root,COG0526@2|Bacteria,1VAPY@1239|Firmicutes,4HJN1@91061|Bacilli,1ZG2C@1386|Bacillus 91061|Bacilli CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - - - - - - - - - - AhpC-TSA SJTD3_k127_1265658_7 886882.PPSC2_c2630 3.862e-07 59.0 COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,1V2NW@1239|Firmicutes,4HGAA@91061|Bacilli,26WTC@186822|Paenibacillaceae 91061|Bacilli K Rhodanese-like domain arsR1 - - - - - - - - - - - HTH_5,Rhodanese SJTD3_k127_1265658_3 324602.Caur_2341 3.137e-42 166.0 COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi,375SK@32061|Chloroflexia 32061|Chloroflexia S PFAM LmbE family protein - - - - - - - - - - - - PIG-L SJTD3_k127_1265658_6 1133849.O3I_018710 6.513e-11 66.0 COG3871@1|root,COG3871@2|Bacteria,2IFC3@201174|Actinobacteria,4G2N2@85025|Nocardiaceae 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx SJTD3_k127_1274328_1 472759.Nhal_1436 9.562e-65 225.0 COG2896@1|root,COG2896@2|Bacteria,1MW3W@1224|Proteobacteria,1RR68@1236|Gammaproteobacteria,1WW2B@135613|Chromatiales 135613|Chromatiales H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate moaA - 4.1.99.22 ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09394 RC03420 ko00000,ko00001,ko01000 - - - Fer4_12,Mob_synth_C,Radical_SAM SJTD3_k127_1274328_3 452637.Oter_0124 8.88e-39 153.0 COG4244@1|root,COG4244@2|Bacteria 2|Bacteria E Membrane - - - - - - - - - - - - DUF2231,Rieske SJTD3_k127_1274328_0 452637.Oter_0125 3.055e-77 267.0 COG2146@1|root,COG4244@1|root,COG2146@2|Bacteria,COG4244@2|Bacteria,46WQG@74201|Verrucomicrobia 74201|Verrucomicrobia P Rieske-like [2Fe-2S] domain - - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske SJTD3_k127_1274328_4 765420.OSCT_1395 4.082e-06 56.0 2A6K3@1|root,30VDR@2|Bacteria,2G9YY@200795|Chloroflexi,377EE@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_1274328_2 479434.Sthe_0434 8.243e-56 206.0 COG0079@1|root,COG0079@2|Bacteria,2G5U4@200795|Chloroflexi,27XEN@189775|Thermomicrobia 189775|Thermomicrobia E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 SJTD3_k127_1286916_2 543632.JOJL01000013_gene9501 3.753e-31 144.0 COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria,4DFG8@85008|Micromonosporales 201174|Actinobacteria S cellulose binding - - - - - - - - - - - - - SJTD3_k127_1286916_3 1382306.JNIM01000001_gene1193 1.018e-29 139.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - CBM_2 SJTD3_k127_1286916_1 1120949.KB903357_gene4933 1.886e-46 195.0 COG4447@1|root,COG4447@2|Bacteria,2IT8P@201174|Actinobacteria 201174|Actinobacteria M phospholipase C - - - - - - - - - - - - - SJTD3_k127_1286916_0 1183438.GKIL_2106 2.803e-50 207.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - CBM_2 SJTD3_k127_1286916_5 1123290.AUDQ01000022_gene745 7.134e-08 67.0 COG0791@1|root,COG0791@2|Bacteria,1V9FW@1239|Firmicutes,4HISN@91061|Bacilli,26FSP@186818|Planococcaceae 91061|Bacilli M S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_1286916_4 1347368.HG964403_gene3974 7.994e-11 72.0 COG4632@1|root,COG4632@2|Bacteria,1UWXQ@1239|Firmicutes,4HWZ4@91061|Bacilli,1ZNWY@1386|Bacillus 91061|Bacilli G S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_129043_1 1101190.ARWB01000001_gene2399 7.915e-24 118.0 COG3227@1|root,COG3227@2|Bacteria,1P416@1224|Proteobacteria,2U2EI@28211|Alphaproteobacteria,370T4@31993|Methylocystaceae 28211|Alphaproteobacteria E Thermolysin metallopeptidase, catalytic domain - - - - - - - - - - - - Peptidase_M4,Peptidase_M4_C SJTD3_k127_129043_0 316067.Geob_1283 2.132e-34 153.0 COG1361@1|root,COG1404@1|root,COG3210@1|root,COG4625@1|root,COG4886@1|root,COG1361@2|Bacteria,COG1404@2|Bacteria,COG3210@2|Bacteria,COG4625@2|Bacteria,COG4886@2|Bacteria,1QUXB@1224|Proteobacteria 1224|Proteobacteria U 6-phosphogluconolactonase activity - - - - - - - - - - - - Autotransporter,Cadherin_3,DUF11,DUF4347,He_PIG,PATR SJTD3_k127_1305717_1 1128421.JAGA01000002_gene1198 1.918e-07 55.0 COG5485@1|root,COG5485@2|Bacteria 2|Bacteria S SnoaL-like polyketide cyclase - - - ko:K15945 ko01057,ko01130,map01057,map01130 - R09330 RC00046 ko00000,ko00001 - - - SnoaL,SnoaL_2 SJTD3_k127_1305717_0 1185652.USDA257_c04170 1.019e-151 505.0 COG3408@1|root,COG3408@2|Bacteria,1MUYU@1224|Proteobacteria,2TQK2@28211|Alphaproteobacteria,4B9N1@82115|Rhizobiaceae 28211|Alphaproteobacteria G Protein involved in amylo-alpha-1,6-glucosidase activity and glycogen biosynthetic process - - - - - - - - - - - - GDE_C,GDE_N_bis SJTD3_k127_1318337_2 649638.Trad_2741 2.122e-50 183.0 COG0566@1|root,COG0566@2|Bacteria 2|Bacteria J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH - 2.1.1.185,2.1.1.34 ko:K00556,ko:K03218,ko:K03437 - - - - ko00000,ko01000,ko03009,ko03016 - - - SpoU_methylase SJTD3_k127_1318337_0 485913.Krac_5497 6.221e-99 332.0 COG0384@1|root,COG0384@2|Bacteria,2G8NU@200795|Chloroflexi 200795|Chloroflexi S PFAM Phenazine biosynthesis PhzC PhzF protein - - 5.3.3.17 ko:K06998 ko00405,ko01130,ko02024,map00405,map01130,map02024 M00835 - - ko00000,ko00001,ko00002,ko01000 - - - PhzC-PhzF SJTD3_k127_1318337_1 525904.Tter_0639 1.23e-82 286.0 COG0761@1|root,COG0761@2|Bacteria,2NP7K@2323|unclassified Bacteria 2|Bacteria IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis ispH - 1.17.7.4,2.7.4.25 ko:K00945,ko:K02945,ko:K03527 ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010 M00052,M00096,M00178 R00158,R00512,R01665,R05884,R08210 RC00002,RC01137,RC01487 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 - - iIT341.HP0400,iLJ478.TM1444 LYTB,S1 SJTD3_k127_1318337_3 926569.ANT_16060 4.457e-19 95.0 COG0640@1|root,COG3860@1|root,COG0640@2|Bacteria,COG3860@2|Bacteria,2G8TH@200795|Chloroflexi 200795|Chloroflexi K regulatory protein, arsR - - - - - - - - - - - - DUF2087,HTH_5 SJTD3_k127_1326501_0 1230342.CTM_02684 1.717e-33 139.0 COG3261@1|root,COG3261@2|Bacteria,1VZGX@1239|Firmicutes,248UJ@186801|Clostridia,36E5K@31979|Clostridiaceae 186801|Clostridia C Belongs to the complex I 49 kDa subunit family - - - - - - - - - - - - Complex1_49kDa,NiFeSe_Hases SJTD3_k127_1337138_2 926554.KI912671_gene240 1.419e-24 109.0 COG5504@1|root,COG5504@2|Bacteria 2|Bacteria O Zn-dependent protease yjfC - - - - - - - - - - - DUF2268 SJTD3_k127_1337138_0 246194.CHY_2323 3.684e-54 194.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,42G61@68295|Thermoanaerobacterales 186801|Clostridia J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK - - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N SJTD3_k127_1337138_1 926560.KE387023_gene1119 5.349e-47 173.0 COG0789@1|root,COG0789@2|Bacteria,1WMUY@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 SJTD3_k127_1342954_0 1121090.KB894700_gene3295 5.653e-115 379.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,4IU6J@91061|Bacilli 91061|Bacilli I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - - 3HCDH,3HCDH_N,ECH_1,ECH_2 SJTD3_k127_1342954_4 869210.Marky_1276 5.84e-29 119.0 COG3224@1|root,COG3224@2|Bacteria,1WMX3@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S SPTR Ethyl tert-butyl ether degradation EthD - - - - - - - - - - - - EthD SJTD3_k127_1342954_3 1042877.GQS_10190 1.016e-37 147.0 COG0346@1|root,arCOG02706@2157|Archaea,2XY0R@28890|Euryarchaeota,24458@183968|Thermococci 183968|Thermococci E Glyoxalase-like domain - GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase_4 SJTD3_k127_1342954_2 558169.AGAV01000005_gene2102 7.529e-44 169.0 COG3483@1|root,COG3483@2|Bacteria,1TR14@1239|Firmicutes,4H9X1@91061|Bacilli 91061|Bacilli E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety kynA GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019752,GO:0020037,GO:0022607,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 ko:K00453 ko00380,ko01100,map00380,map01100 M00038 R00678 RC00356 ko00000,ko00001,ko00002,ko01000 - - - Trp_dioxygenase SJTD3_k127_1342954_1 1128421.JAGA01000002_gene1277 1.656e-51 193.0 COG1525@1|root,COG1572@1|root,COG1525@2|Bacteria,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - Alpha_L_fucos,Calx-beta,F5_F8_type_C,G5,SNase,Trypsin_2,YSIRK_signal SJTD3_k127_1346313_1 1267535.KB906767_gene2223 3.743e-62 229.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - ko:K02847 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 9.B.67.4,9.B.67.5 - - Wzy_C SJTD3_k127_1346313_0 1089553.Tph_c02730 2.162e-108 362.0 COG0438@1|root,COG0438@2|Bacteria,1UZ0I@1239|Firmicutes,24M87@186801|Clostridia,42HYK@68295|Thermoanaerobacterales 186801|Clostridia M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_1346313_2 56780.SYN_01135 1.321e-26 119.0 COG1428@1|root,COG1428@2|Bacteria 2|Bacteria F Deoxynucleoside kinase - - - - - - - - - - - - - SJTD3_k127_1346313_3 56780.SYN_01139 9.478e-18 86.0 COG0125@1|root,COG0125@2|Bacteria,1RA0K@1224|Proteobacteria 1224|Proteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - - - - - - - - - - - SJTD3_k127_1348720_1 383372.Rcas_1885 3.593e-176 557.0 COG1085@1|root,COG1085@2|Bacteria,2G6K5@200795|Chloroflexi,3759B@32061|Chloroflexia 32061|Chloroflexia H PFAM galactose-1-phosphate uridyl transferase domain protein - - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf SJTD3_k127_1348720_3 373903.Hore_20600 2.063e-78 278.0 COG2723@1|root,COG2723@2|Bacteria 2|Bacteria G beta-glucosidase activity - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 SJTD3_k127_1348720_0 1121377.KB906402_gene3265 1.57e-234 741.0 COG3507@1|root,COG3507@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 43 family - - 3.2.1.99 ko:K06113 - - - - ko00000,ko01000 - GH43 - Glyco_hydro_43 SJTD3_k127_1348720_2 926569.ANT_11430 3.157e-119 393.0 COG3507@1|root,COG3507@2|Bacteria,2G7I9@200795|Chloroflexi 200795|Chloroflexi G Glycosyl hydrolases family 43 - - 3.2.1.37,3.2.1.55 ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 - R01433,R01762 RC00467 ko00000,ko00001,ko01000 - GH43,GH51 - Glyco_hydro_43 SJTD3_k127_1351746_4 743718.Isova_0314 1.111e-20 97.0 COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,4F3S3@85017|Promicromonosporaceae 201174|Actinobacteria F Phosphoribosylglycinamide synthetase, C domain purD GO:0008150,GO:0040007 6.3.3.1,6.3.4.13 ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144,R04208 RC00090,RC00166,RC01100 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N SJTD3_k127_1351746_3 350688.Clos_1595 2.246e-40 155.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,24JFS@186801|Clostridia,36ITW@31979|Clostridiaceae 186801|Clostridia L nudix family nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX SJTD3_k127_1351746_2 1303518.CCALI_01414 1.826e-46 178.0 COG1573@1|root,COG1573@2|Bacteria 2|Bacteria L deaminated base DNA N-glycosylase activity ung2 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 ko:K21929 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG SJTD3_k127_1351746_1 1131266.ARWQ01000003_gene1584 1.039e-149 489.0 COG0516@1|root,arCOG00612@2157|Archaea,41S7R@651137|Thaumarchaeota 651137|Thaumarchaeota F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH SJTD3_k127_1351746_0 671143.DAMO_0386 3.881e-293 928.0 COG1048@1|root,COG1048@2|Bacteria,2NNWW@2323|unclassified Bacteria 2|Bacteria C Aconitase C-terminal domain dmdA - 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_2763 Aconitase,Aconitase_C SJTD3_k127_1351900_0 479434.Sthe_1490 1.674e-46 170.0 COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia 200795|Chloroflexi S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn SJTD3_k127_1351900_1 1220589.CD32_22660 6.984e-20 105.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,3IWAP@400634|Lysinibacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CHB_HEX_C_1,Gram_pos_anchor,LTD,Metallophos,SLH SJTD3_k127_1351900_2 1242864.D187_000827 5.995e-14 85.0 COG1404@1|root,COG3386@1|root,COG1404@2|Bacteria,COG3386@2|Bacteria,1MU3S@1224|Proteobacteria,42SPI@68525|delta/epsilon subdivisions,2X5HN@28221|Deltaproteobacteria 28221|Deltaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 SJTD3_k127_1352558_1 316274.Haur_4627 1.843e-91 320.0 COG0188@1|root,COG0188@2|Bacteria,2G5Q2@200795|Chloroflexi,37520@32061|Chloroflexia 32061|Chloroflexia L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV SJTD3_k127_1352558_5 383372.Rcas_1121 1.766e-07 56.0 COG3847@1|root,COG3847@2|Bacteria,2GB1R@200795|Chloroflexi,377RD@32061|Chloroflexia 32061|Chloroflexia U PFAM Flp Fap pilin component - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap SJTD3_k127_1352558_4 383372.Rcas_1121 1.012e-07 56.0 COG3847@1|root,COG3847@2|Bacteria,2GB1R@200795|Chloroflexi,377RD@32061|Chloroflexia 32061|Chloroflexia U PFAM Flp Fap pilin component - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap SJTD3_k127_1352558_6 383372.Rcas_1121 0.000838 46.0 COG3847@1|root,COG3847@2|Bacteria,2GB1R@200795|Chloroflexi,377RD@32061|Chloroflexia 32061|Chloroflexia U PFAM Flp Fap pilin component - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap SJTD3_k127_1352558_0 765420.OSCT_0728 3.969e-92 317.0 COG4585@1|root,COG4585@2|Bacteria,2G71C@200795|Chloroflexi,3752U@32061|Chloroflexia 32061|Chloroflexia T histidine kinase, dimerisation and phosphoacceptor region - - 2.7.13.3 ko:K07777 ko02020,map02020 M00478 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DegS,HATPase_c,HisKA_3 SJTD3_k127_1352558_2 1121272.KB903249_gene2255 8.073e-42 160.0 COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales 201174|Actinobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase SJTD3_k127_1352558_3 765420.OSCT_0664 3.233e-31 134.0 COG1287@1|root,COG1287@2|Bacteria,2GANB@200795|Chloroflexi,376UI@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_1353112_0 221288.JH992901_gene2423 8.099e-117 383.0 28HGI@1|root,2Z7SC@2|Bacteria,1FZZQ@1117|Cyanobacteria,1JHV5@1189|Stigonemataceae 1117|Cyanobacteria - - - - - - - - - - - - - - - SJTD3_k127_1353112_3 485913.Krac_5622 4.996e-43 165.0 COG5207@1|root,COG5207@2|Bacteria 2|Bacteria O Pfam Zn-finger in ubiquitin-hydrolases and other protein - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N,zf-UBP SJTD3_k127_1353112_2 1041930.Mtc_1585 5.147e-47 177.0 COG1985@1|root,arCOG01484@2157|Archaea,2XU47@28890|Euryarchaeota,2N96I@224756|Methanomicrobia 224756|Methanomicrobia H PFAM bifunctional deaminase-reductase domain protein - - 1.1.1.302 ko:K14654 ko00740,ko01100,map00740,map01100 - R09375,R09376 RC00933 ko00000,ko00001,ko01000 - - - RibD_C SJTD3_k127_1353112_1 1254432.SCE1572_28920 1.346e-92 311.0 COG0807@1|root,COG0807@2|Bacteria,1MWZR@1224|Proteobacteria,42N2Q@68525|delta/epsilon subdivisions,2X9TY@28221|Deltaproteobacteria,2YV7W@29|Myxococcales 28221|Deltaproteobacteria H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate ribA - 3.5.4.25 ko:K01497 ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024 M00125 R00425 RC00293,RC02504 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydro2 SJTD3_k127_1353112_5 1122139.KB907872_gene2243 0.0002926 46.0 COG1028@1|root,COG1028@2|Bacteria,1MUWC@1224|Proteobacteria,1SMS6@1236|Gammaproteobacteria 1236|Gammaproteobacteria IQ NAD dependent epimerase/dehydratase family - - - - - - - - - - - - adh_short_C2 SJTD3_k127_1353112_4 749414.SBI_02032 4.085e-08 55.0 COG1028@1|root,COG1028@2|Bacteria,2GXKF@201174|Actinobacteria 201174|Actinobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short SJTD3_k127_1354404_1 429009.Adeg_0369 6.905e-63 220.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,24FQD@186801|Clostridia,42G0W@68295|Thermoanaerobacterales 186801|Clostridia F Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily pyrR - 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - iHN637.CLJU_RS05275 Pribosyltran SJTD3_k127_1354404_2 485913.Krac_9989 1.511e-30 125.0 COG0640@1|root,COG0640@2|Bacteria,2G78R@200795|Chloroflexi 200795|Chloroflexi K PFAM regulatory protein, ArsR - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 SJTD3_k127_1354404_0 696369.KI912183_gene1805 1.357e-213 689.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,260Y1@186807|Peptococcaceae 186801|Clostridia P ATPase, P-type (transporting), HAD superfamily, subfamily IC cadA - 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase SJTD3_k127_1361740_3 635013.TherJR_1359 5.654e-14 76.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,261N9@186807|Peptococcaceae 186801|Clostridia J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr - - ko:K02838 - - - - ko00000,ko03012 - - - RRF SJTD3_k127_1361740_0 997346.HMPREF9374_0713 3.315e-98 329.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli,27BDV@186824|Thermoactinomycetaceae 91061|Bacilli F Amino acid kinase family pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase SJTD3_k127_1361740_2 311424.DhcVS_320 3.153e-51 186.0 COG0264@1|root,COG0264@2|Bacteria,2G6MJ@200795|Chloroflexi,34CST@301297|Dehalococcoidia 301297|Dehalococcoidia J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf - - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS SJTD3_k127_1361740_1 525904.Tter_1520 7.938e-98 329.0 COG0052@1|root,COG0052@2|Bacteria,2NP4M@2323|unclassified Bacteria 2|Bacteria J Belongs to the universal ribosomal protein uS2 family rpsB GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 SJTD3_k127_1369586_1 926550.CLDAP_29550 2.15e-07 62.0 COG3835@1|root,COG3835@2|Bacteria 2|Bacteria KT positive regulation of transcription, DNA-templated - - - ko:K09684 - - - - ko00000,ko03000 - - - GAF_2,HTH_30,PucR SJTD3_k127_1369586_0 309801.trd_A0621 4.701e-142 462.0 COG0477@1|root,COG2814@2|Bacteria,2G8FT@200795|Chloroflexi,27Z09@189775|Thermomicrobia 189775|Thermomicrobia EGP Sugar (and other) transporter - - - ko:K08369 - - - - ko00000,ko02000 2.A.1 - - Sugar_tr SJTD3_k127_1373757_0 266117.Rxyl_2946 2.342e-131 449.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4CPZ0@84995|Rubrobacteria 84995|Rubrobacteria T Transcriptional regulator - - - - - - - - - - - - BTAD,Trans_reg_C SJTD3_k127_1373757_1 665029.EAMY_2595 8.8e-06 57.0 28I6Y@1|root,2Z89T@2|Bacteria,1R4DR@1224|Proteobacteria,1RRDT@1236|Gammaproteobacteria,3X4X5@551|Erwinia 1236|Gammaproteobacteria S Enhanced serine sensitivity sseB - - - - - - - - - - - SseB,SseB_C SJTD3_k127_1398478_1 266117.Rxyl_0455 4.701e-116 387.0 COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CQCU@84995|Rubrobacteria 84995|Rubrobacteria E Peptidase dimerisation domain - - - - - - - - - - - - M20_dimer,Peptidase_M20 SJTD3_k127_1398478_0 316274.Haur_0966 4.605e-240 763.0 COG3291@1|root,COG3291@2|Bacteria 2|Bacteria S metallopeptidase activity - - - - - - - - - - - - LTD,PKD,Reprolysin_4,Reprolysin_5 SJTD3_k127_1400419_0 1128421.JAGA01000002_gene1001 2.053e-45 184.0 COG1807@1|root,COG1807@2|Bacteria,2NS23@2323|unclassified Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - Glyco_transf_22,PMT,PMT_2 SJTD3_k127_1400419_2 436229.JOEH01000015_gene6038 5.585e-05 53.0 COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria,2NHC0@228398|Streptacidiphilus 201174|Actinobacteria K Sigma-70, region 4 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_1400419_1 448385.sce6683 1.362e-20 105.0 COG2244@1|root,COG2244@2|Bacteria,1MUN5@1224|Proteobacteria,42MH6@68525|delta/epsilon subdivisions,2WKH9@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C SJTD3_k127_1419782_0 479434.Sthe_1693 3.804e-56 203.0 COG3693@1|root,COG5479@1|root,COG3693@2|Bacteria,COG5479@2|Bacteria,2GBGU@200795|Chloroflexi,27Y52@189775|Thermomicrobia 200795|Chloroflexi M Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase SJTD3_k127_1419782_1 1382306.JNIM01000001_gene4215 7.038e-18 93.0 COG1466@1|root,COG1466@2|Bacteria,2G6XX@200795|Chloroflexi 200795|Chloroflexi L TIGRFAM DNA polymerase III, delta' subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta SJTD3_k127_142945_1 479434.Sthe_1991 2.5e-125 420.0 COG0773@1|root,COG0773@2|Bacteria,2G5J4@200795|Chloroflexi,27XZD@189775|Thermomicrobia 189775|Thermomicrobia M Mur ligase family, catalytic domain murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SJTD3_k127_142945_2 525904.Tter_1607 1.19e-106 358.0 COG0772@1|root,COG0772@2|Bacteria,2NP3P@2323|unclassified Bacteria 2|Bacteria D Belongs to the SEDS family ftsW GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008360,GO:0009987,GO:0015647,GO:0015648,GO:0015835,GO:0015836,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032153,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051179,GO:0051234,GO:0051301,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505 2.4.1.227 ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 2.A.103.1 GT28 - FTSW_RODA_SPOVE SJTD3_k127_142945_0 1128421.JAGA01000002_gene1028 3.664e-135 445.0 COG0771@1|root,COG0771@2|Bacteria,2NP27@2323|unclassified Bacteria 2|Bacteria M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M SJTD3_k127_1437471_1 702450.CUW_1637 5.348e-44 170.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,3VR4Y@526524|Erysipelotrichia 526524|Erysipelotrichia GM Capsular polysaccharide biosynthesis protein - - - - - - - - - - - - - SJTD3_k127_1437471_0 383372.Rcas_3668 2.874e-72 250.0 COG0489@1|root,COG0489@2|Bacteria,2G5WM@200795|Chloroflexi,375EN@32061|Chloroflexia 32061|Chloroflexia D TIGRFAM capsular exopolysaccharide family - - 2.7.10.2 ko:K08253 - - - - ko00000,ko01000 - - - CbiA,ParA SJTD3_k127_1437471_2 1128421.JAGA01000003_gene3427 5.25e-06 50.0 COG3944@1|root,COG3944@2|Bacteria 2|Bacteria M capsule polysaccharide biosynthetic process - - - ko:K16692 - - - - ko00000,ko01000,ko01001 - - - GNVR,Wzz SJTD3_k127_1443852_3 1382306.JNIM01000001_gene4158 1.387e-24 111.0 2ARWP@1|root,31H8I@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_1443852_0 316274.Haur_0506 3.862e-168 537.0 COG0626@1|root,COG0626@2|Bacteria,2G5M2@200795|Chloroflexi,376G2@32061|Chloroflexia 32061|Chloroflexia E PFAM Cys Met metabolism pyridoxal-phosphate-dependent - - 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP SJTD3_k127_1443852_2 1382306.JNIM01000001_gene1439 2.445e-35 151.0 COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi 200795|Chloroflexi S integral membrane protein - - - - - - - - - - - - Mannosyl_trans2 SJTD3_k127_1443852_1 997346.HMPREF9374_1227 1.815e-50 189.0 COG0861@1|root,COG0861@2|Bacteria,1V487@1239|Firmicutes,4HH2E@91061|Bacilli,27BSY@186824|Thermoactinomycetaceae 91061|Bacilli P Integral membrane protein TerC family - - - - - - - - - - - - TerC SJTD3_k127_1444388_1 926550.CLDAP_09460 1.102e-115 383.0 COG0136@1|root,COG0136@2|Bacteria,2G5T9@200795|Chloroflexi 200795|Chloroflexi E Belongs to the aspartate-semialdehyde dehydrogenase family asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC SJTD3_k127_1444388_2 1521187.JPIM01000015_gene3734 1.753e-76 276.0 COG0460@1|root,COG0460@2|Bacteria,2G8BZ@200795|Chloroflexi,376ET@32061|Chloroflexia 32061|Chloroflexia E PFAM homoserine dehydrogenase - - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - - Homoserine_dh,NAD_binding_3 SJTD3_k127_1444388_0 926550.CLDAP_10210 3.493e-126 419.0 COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi 200795|Chloroflexi E Belongs to the aspartokinase family metL - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 SJTD3_k127_145804_3 265072.Mfla_1749 2.932e-34 135.0 COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2VUZH@28216|Betaproteobacteria,2KKCA@206350|Nitrosomonadales 206350|Nitrosomonadales S PFAM SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc SJTD3_k127_145804_4 1232410.KI421424_gene1683 1.394e-13 79.0 292ZR@1|root,2ZQH4@2|Bacteria,1Q6C4@1224|Proteobacteria,432UF@68525|delta/epsilon subdivisions,2WXCR@28221|Deltaproteobacteria,43VSP@69541|Desulfuromonadales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_145804_1 525904.Tter_2371 5.725e-67 250.0 COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3290@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,2NQT3@2323|unclassified Bacteria 2|Bacteria T SMART ATP-binding region ATPase domain protein - - - - - - - - - - - - CBS,CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg SJTD3_k127_145804_5 338963.Pcar_2565 5.354e-07 63.0 COG5001@1|root,COG5001@2|Bacteria,1MU2C@1224|Proteobacteria,42M0W@68525|delta/epsilon subdivisions,2WUAW@28221|Deltaproteobacteria,43U3F@69541|Desulfuromonadales 28221|Deltaproteobacteria T Putative diguanylate phosphodiesterase - - - - - - - - - - - - EAL,GGDEF,PAS_3,Response_reg SJTD3_k127_145804_2 309801.trd_1763 1.612e-61 228.0 COG2340@1|root,COG5479@1|root,COG2340@2|Bacteria,COG5479@2|Bacteria,2GBCS@200795|Chloroflexi,27YT2@189775|Thermomicrobia 189775|Thermomicrobia M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP SJTD3_k127_145804_6 218495.SUB1809 1.912e-05 52.0 COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,4HJ76@91061|Bacilli 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor aseR - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_5 SJTD3_k127_145804_0 479434.Sthe_1716 8.68e-170 537.0 COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,27Y0U@189775|Thermomicrobia 189775|Thermomicrobia I Myo-inositol-1-phosphate synthase - - 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth SJTD3_k127_1467310_1 383372.Rcas_0422 1.359e-60 222.0 COG2197@1|root,COG4963@1|root,COG2197@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia 32061|Chloroflexia D PFAM response regulator receiver - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,Response_reg SJTD3_k127_1467310_0 309801.trd_1011 4.369e-161 520.0 COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia 189775|Thermomicrobia U Type II/IV secretion system protein - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE SJTD3_k127_1467310_2 1382356.JQMP01000003_gene2237 3.817e-56 208.0 COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi,27XX2@189775|Thermomicrobia 189775|Thermomicrobia U Type II secretion system (T2SS), protein F - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF SJTD3_k127_1467310_3 1157490.EL26_17580 1.456e-06 57.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,1TQXZ@1239|Firmicutes,4HB0B@91061|Bacilli,27929@186823|Alicyclobacillaceae 91061|Bacilli S Putative glutamine amidotransferase - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - GATase1_like,VWA,VWA_2,VWA_3 SJTD3_k127_1468165_0 926560.KE387027_gene274 2.911e-72 255.0 arCOG10517@1|root,31Y5Z@2|Bacteria,1WMKM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - SJTD3_k127_1468165_1 1227739.Hsw_0070 2.892e-15 79.0 COG1409@1|root,COG3419@1|root,COG1409@2|Bacteria,COG3419@2|Bacteria,4NGK2@976|Bacteroidetes,47NR3@768503|Cytophagia 976|Bacteroidetes NU PFAM metallophosphoesterase - - - - - - - - - - - - Metallophos,Pur_ac_phosph_N SJTD3_k127_1468165_2 1122138.AQUZ01000002_gene2075 2.505e-12 74.0 2EYIJ@1|root,33RSC@2|Bacteria,2IPA3@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_1483456_1 1280390.CBQR020000072_gene1544 6.545e-24 106.0 COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae 91061|Bacilli S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 SJTD3_k127_1483456_0 1128421.JAGA01000002_gene1247 1.485e-189 640.0 COG0744@1|root,COG0744@2|Bacteria 2|Bacteria M Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors mrcB - 2.4.1.129,3.4.16.4 ko:K05365 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,UB2H SJTD3_k127_1483456_2 290633.GOX1551 2.22e-19 92.0 COG0745@1|root,COG0745@2|Bacteria,1RHDD@1224|Proteobacteria,2U9G2@28211|Alphaproteobacteria,2JSYP@204441|Rhodospirillales 204441|Rhodospirillales KT Response regulator receiver domain - - - ko:K03413 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko02022,ko02035 - - - Response_reg SJTD3_k127_149555_0 1385935.N836_34705 5.873e-45 171.0 COG0703@1|root,COG0703@2|Bacteria,1G7N0@1117|Cyanobacteria 1117|Cyanobacteria E Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - - - - - - - - - - - SJTD3_k127_149555_1 479434.Sthe_0077 3.612e-25 109.0 2DQ3G@1|root,334K8@2|Bacteria,2G77Z@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF2568) - - - - - - - - - - - - DUF2568 SJTD3_k127_1505996_4 1128421.JAGA01000002_gene1623 3.777e-37 146.0 COG2606@1|root,COG2606@2|Bacteria 2|Bacteria S Cys-tRNA(Pro) hydrolase activity ybaK GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit SJTD3_k127_1505996_5 591167.Sfla_6338 3.9e-33 141.0 COG1672@1|root,COG2319@1|root,COG1672@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria 201174|Actinobacteria F WD-40 repeat - - - - - - - - - - - - AAA_16,NACHT,Pentapeptide,TIR_2,WD40 SJTD3_k127_1505996_0 485913.Krac_2581 4.315e-135 447.0 COG1816@1|root,COG1816@2|Bacteria,2G6AT@200795|Chloroflexi 200795|Chloroflexi F PFAM Adenosine AMP deaminase - - 3.5.4.4,3.5.4.40 ko:K01488,ko:K18286 ko00130,ko00230,ko01100,ko01110,ko05340,map00130,map00230,map01100,map01110,map05340 - R01560,R02556,R10695 RC00477 ko00000,ko00001,ko01000 - - - A_deaminase SJTD3_k127_1505996_1 706587.Desti_0703 1.454e-73 249.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WNIG@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA SJTD3_k127_1505996_8 706587.Desti_0703 8.082e-22 98.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,42MAJ@68525|delta/epsilon subdivisions,2WNIG@28221|Deltaproteobacteria 28221|Deltaproteobacteria O PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA SJTD3_k127_1505996_2 357808.RoseRS_2133 9.738e-61 218.0 COG3311@1|root,COG4936@1|root,COG3311@2|Bacteria,COG4936@2|Bacteria 2|Bacteria KT Sensory domain found in PocR - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - HTH_17,PocR SJTD3_k127_1505996_6 194439.CT0847 7.605e-28 113.0 COG0425@1|root,COG0425@2|Bacteria,1FE4M@1090|Chlorobi 1090|Chlorobi O Belongs to the sulfur carrier protein TusA family - - - ko:K04085 ko04122,map04122 - - - ko00000,ko00001,ko01000,ko03016 - - - TusA SJTD3_k127_1505996_3 644282.Deba_2661 2.87e-47 177.0 COG2210@1|root,COG2210@2|Bacteria,1RDUG@1224|Proteobacteria,42VFB@68525|delta/epsilon subdivisions,2WRRQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria S DsrE/DsrF/DrsH-like family - - - - - - - - - - - - DrsE_2 SJTD3_k127_1505996_7 478741.JAFS01000002_gene435 1.32e-23 102.0 COG2210@1|root,COG2210@2|Bacteria,46ZAV@74201|Verrucomicrobia,37GMZ@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia S DsrE/DsrF-like family - - - - - - - - - - - - DrsE_2 SJTD3_k127_1519685_1 255470.cbdbA367 1.757e-72 255.0 COG1597@1|root,COG1597@2|Bacteria,2G6UK@200795|Chloroflexi,34CPQ@301297|Dehalococcoidia 301297|Dehalococcoidia I Diacylglycerol kinase catalytic domain - - - - - - - - - - - - DAGK_cat SJTD3_k127_1519685_2 646529.Desaci_0681 8.095e-31 129.0 COG2020@1|root,COG2020@2|Bacteria,1VKIT@1239|Firmicutes 1239|Firmicutes O PFAM Isoprenylcysteine carboxyl methyltransferase - - - - - - - - - - - - ICMT,PEMT SJTD3_k127_1519685_0 40571.JOEA01000005_gene4054 3.481e-96 323.0 COG0702@1|root,COG0702@2|Bacteria,2GK1A@201174|Actinobacteria,4E577@85010|Pseudonocardiales 201174|Actinobacteria GM NmrA-like family - - - - - - - - - - - - NmrA SJTD3_k127_1519685_3 525904.Tter_0916 1.914e-14 76.0 COG1314@1|root,COG1314@2|Bacteria,2NS1U@2323|unclassified Bacteria 2|Bacteria U Preprotein translocase SecG subunit secG GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG SJTD3_k127_1520950_1 1172188.KB911824_gene3342 1.229e-26 117.0 COG4995@1|root,COG4995@2|Bacteria,2ICQB@201174|Actinobacteria,4FG53@85021|Intrasporangiaceae 201174|Actinobacteria E CHAT domain - - - - - - - - - - - - CBM9_1,CHAT,Peptidase_S8,WD40 SJTD3_k127_1520950_0 1121272.KB903250_gene2872 8.895e-36 147.0 COG2267@1|root,COG2267@2|Bacteria,2IGKW@201174|Actinobacteria,4DIAN@85008|Micromonosporales 201174|Actinobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 SJTD3_k127_1520950_2 1382356.JQMP01000001_gene820 2.559e-17 85.0 COG4242@1|root,COG4242@2|Bacteria,2G6C3@200795|Chloroflexi,27XM7@189775|Thermomicrobia 189775|Thermomicrobia PQ Belongs to the peptidase S51 family - - - - - - - - - - - - - SJTD3_k127_1528913_0 459495.SPLC1_S240990 1.584e-13 83.0 COG0457@1|root,COG0457@2|Bacteria,1G4DA@1117|Cyanobacteria,1HI8X@1150|Oscillatoriales 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - - SJTD3_k127_1547172_0 485913.Krac_12535 2.259e-165 524.0 COG0085@1|root,COG0085@2|Bacteria,2G5VH@200795|Chloroflexi 200795|Chloroflexi K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 SJTD3_k127_1547172_1 383372.Rcas_1597 1.398e-84 284.0 COG0086@1|root,COG0086@2|Bacteria,2G632@200795|Chloroflexi,374SV@32061|Chloroflexia 32061|Chloroflexia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 SJTD3_k127_1558633_0 649638.Trad_1966 7.105e-70 243.0 COG1814@1|root,COG1814@2|Bacteria,1WMZB@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S VIT family - - - - - - - - - - - - VIT1 SJTD3_k127_1558633_1 479434.Sthe_1882 1.103e-52 203.0 COG4758@1|root,COG4758@2|Bacteria,2G93M@200795|Chloroflexi 200795|Chloroflexi S membrane - - - - - - - - - - - - - SJTD3_k127_1575467_1 1454004.AW11_00251 5.296e-24 108.0 COG0457@1|root,COG0457@2|Bacteria,1MUZK@1224|Proteobacteria,2VR7H@28216|Betaproteobacteria 28216|Betaproteobacteria M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Glyco_transf_9,TPR_1,TPR_11,TPR_16,TPR_2,TPR_4,TPR_8 SJTD3_k127_1575467_0 296591.Bpro_4144 4.616e-213 674.0 COG4147@1|root,COG4147@2|Bacteria,1MVJ8@1224|Proteobacteria,2VH3P@28216|Betaproteobacteria,4AA9Z@80864|Comamonadaceae 28216|Betaproteobacteria S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family actP_1 - - ko:K14393 - - - - ko00000,ko02000 2.A.21.7 - - SSF SJTD3_k127_1579285_0 316274.Haur_4885 1.166e-122 401.0 COG1363@1|root,COG1363@2|Bacteria,2G6EE@200795|Chloroflexi,376NV@32061|Chloroflexia 32061|Chloroflexia G peptidase M42 family protein - - - - - - - - - - - - Peptidase_M42 SJTD3_k127_1579285_2 1128421.JAGA01000002_gene348 4.125e-19 94.0 29AKR@1|root,2ZXKP@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_1579285_1 1382306.JNIM01000001_gene1964 6.066e-106 355.0 COG0520@1|root,COG0520@2|Bacteria 2|Bacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine ycbU - - - - - - - - - - - Aminotran_5 SJTD3_k127_1593420_3 700598.Niako_2729 1.785e-51 190.0 COG0596@1|root,COG0596@2|Bacteria,4PNUJ@976|Bacteroidetes,1IXQ1@117747|Sphingobacteriia 976|Bacteroidetes F Thioesterase domain - - - - - - - - - - - - Abhydrolase_1,Hydrolase_4 SJTD3_k127_1593420_1 1123508.JH636440_gene2035 6.312e-102 340.0 COG0451@1|root,COG0451@2|Bacteria,2IXJ5@203682|Planctomycetes 203682|Planctomycetes M epimerase dehydratase - - 5.1.3.6 ko:K08679 ko00520,ko01100,map00520,map01100 - R01385 RC00289 ko00000,ko00001,ko01000 - - - Epimerase,GDP_Man_Dehyd SJTD3_k127_1593420_2 383372.Rcas_4268 2.175e-74 271.0 COG3307@1|root,COG3307@2|Bacteria,2G6TE@200795|Chloroflexi,375HE@32061|Chloroflexia 32061|Chloroflexia M PFAM O-antigen polymerase - - - - - - - - - - - - Wzy_C SJTD3_k127_1593420_0 479434.Sthe_1157 3.842e-129 420.0 COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi,27XSM@189775|Thermomicrobia 189775|Thermomicrobia GM 3-beta hydroxysteroid dehydrogenase/isomerase family - - 4.1.1.35 ko:K08678 ko00520,ko01100,map00520,map01100 M00361 R01384 RC00508 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd SJTD3_k127_1593420_4 1944.JOAZ01000018_gene3943 2.922e-11 67.0 2EPVB@1|root,33HFT@2|Bacteria,2IQ3M@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_1614528_0 1173028.ANKO01000014_gene1000 6.35e-62 234.0 COG0784@1|root,COG3290@1|root,COG5000@1|root,COG5002@1|root,COG0784@2|Bacteria,COG3290@2|Bacteria,COG5000@2|Bacteria,COG5002@2|Bacteria,1GPYK@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - HATPase_c,HisKA,PAS_4,PAS_8,PAS_9,Response_reg SJTD3_k127_1620781_1 525904.Tter_1796 2.324e-33 135.0 COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria 2|Bacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS20740 ACCA,Carboxyl_trans SJTD3_k127_1620781_0 278963.ATWD01000001_gene4079 6.017e-107 354.0 COG0624@1|root,COG0624@2|Bacteria,3Y3TZ@57723|Acidobacteria,2JIUW@204432|Acidobacteriia 204432|Acidobacteriia E PFAM peptidase - - - - - - - - - - - - M20_dimer,Peptidase_M20 SJTD3_k127_1635509_1 1120948.KB903219_gene767 1.33e-06 54.0 COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DXJ5@85010|Pseudonocardiales 201174|Actinobacteria E Alcohol dehydrogenase GroES-like domain adh - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N SJTD3_k127_1635509_0 1382356.JQMP01000003_gene2064 4.868e-182 582.0 COG0154@1|root,COG0154@2|Bacteria,2G7KI@200795|Chloroflexi,27YVS@189775|Thermomicrobia 189775|Thermomicrobia J Amidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase SJTD3_k127_1637838_1 869210.Marky_2090 4.645e-66 231.0 COG0157@1|root,COG0157@2|Bacteria,1WIHZ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Belongs to the NadC ModD family nadC - 2.4.2.19 ko:K00767 ko00760,ko01100,map00760,map01100 M00115 R03348 RC02877 ko00000,ko00001,ko00002,ko01000 - - - QRPTase_C,QRPTase_N SJTD3_k127_1637838_0 479434.Sthe_0863 4.57e-106 352.0 COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi,27Z0R@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA SJTD3_k127_1646062_0 290397.Adeh_2304 5.177e-266 828.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.3,1.8.5.5 ko:K07306,ko:K08352 ko00920,ko01120,map00920,map01120 - R09501,R10149 RC02555,RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.3,5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_1660779_4 243159.AFE_1122 3.181e-12 70.0 2DNWH@1|root,32ZJ0@2|Bacteria,1NBJK@1224|Proteobacteria,1SJ5C@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Protein of unknown function (DUF4031) - - - - - - - - - - - - DUF4031 SJTD3_k127_1660779_0 525904.Tter_2120 1.263e-81 279.0 COG0745@1|root,COG0745@2|Bacteria 525904.Tter_2120|- T phosphorelay signal transduction system - - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - - SJTD3_k127_1660779_1 479434.Sthe_3406 9.59e-75 282.0 COG0477@1|root,COG0642@1|root,COG0793@1|root,COG2199@1|root,COG2203@1|root,COG3437@1|root,COG0477@2|Bacteria,COG0793@2|Bacteria,COG2199@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3437@2|Bacteria,2G6ND@200795|Chloroflexi,27Y5Y@189775|Thermomicrobia 189775|Thermomicrobia T HD domain - - - - - - - - - - - - GAF_2,GGDEF,HD SJTD3_k127_1660779_3 67332.FM21_15730 1.134e-15 89.0 COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria 201174|Actinobacteria H Belongs to the FPP GGPP synthase family - - 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00365 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt SJTD3_k127_1660779_2 1173027.Mic7113_2082 3.586e-37 148.0 COG0454@1|root,COG0456@2|Bacteria,1G407@1117|Cyanobacteria,1H9GX@1150|Oscillatoriales 1117|Cyanobacteria K PFAM Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_167973_0 1382306.JNIM01000001_gene3583 1.542e-143 469.0 COG0578@1|root,COG0578@2|Bacteria 2|Bacteria C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family glpD GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.1.5.3 ko:K00111 ko00564,ko01110,map00564,map01110 - R00848 RC00029 ko00000,ko00001,ko01000 - - - DAO,DAO_C SJTD3_k127_167973_1 926569.ANT_08060 8.788e-27 112.0 COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi 200795|Chloroflexi M PFAM sugar isomerase (SIS) - - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - SIS SJTD3_k127_1679989_1 273068.TTE0899 1.16e-21 103.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,42GQR@68295|Thermoanaerobacterales 186801|Clostridia M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC SJTD3_k127_1679989_0 525904.Tter_1629 5.507e-164 525.0 COG1077@1|root,COG1077@2|Bacteria,2NNVU@2323|unclassified Bacteria 2|Bacteria D MreB/Mbl protein mreB - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SJTD3_k127_1681371_1 1089553.Tph_c21880 1.352e-119 395.0 COG0815@1|root,COG0815@2|Bacteria,1V095@1239|Firmicutes,24B2E@186801|Clostridia 186801|Clostridia M Carbon-nitrogen hydrolase - - - ko:K03820 - - - - ko00000,ko01000 - GT2 - CN_hydrolase SJTD3_k127_1681371_2 1128421.JAGA01000004_gene2697 3.849e-83 282.0 COG1878@1|root,COG1878@2|Bacteria 2|Bacteria S arylformamidase activity - - - - - - - - - - - - Cyclase SJTD3_k127_1681371_9 264198.Reut_B5045 1.053e-05 55.0 COG5553@1|root,COG5553@2|Bacteria,1R5RR@1224|Proteobacteria,2VQ9W@28216|Betaproteobacteria,1K60U@119060|Burkholderiaceae 28216|Betaproteobacteria C cysteine dioxygenase type I - - - - - - - - - - - - CDO_I SJTD3_k127_1681371_5 1380354.JIAN01000005_gene2604 3.64e-58 207.0 COG0346@1|root,COG0346@2|Bacteria,2IKCC@201174|Actinobacteria 201174|Actinobacteria E lactoylglutathione lyase activity - - - - - - - - - - - - - SJTD3_k127_1681371_0 1183438.GKIL_1369 4.104e-157 540.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - SBBP SJTD3_k127_1681371_6 933115.GPDM_10955 6.171e-21 110.0 COG2333@1|root,COG2333@2|Bacteria,1UNCH@1239|Firmicutes,4IU9T@91061|Bacilli,26GJ8@186818|Planococcaceae 91061|Bacilli S S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_1681371_3 502025.Hoch_5296 7.102e-75 260.0 COG0656@1|root,COG0656@2|Bacteria,1MX6S@1224|Proteobacteria,4383U@68525|delta/epsilon subdivisions,2X3DT@28221|Deltaproteobacteria,2YVM7@29|Myxococcales 28221|Deltaproteobacteria S Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red SJTD3_k127_1681371_8 1245475.ANAE01000162_gene2530 1.566e-13 81.0 COG1708@1|root,COG1708@2|Bacteria,2GK36@201174|Actinobacteria 201174|Actinobacteria S nucleotidyltransferase activity - - - ko:K18236 - - - - ko00000,ko01504 - - - - SJTD3_k127_1681371_7 405948.SACE_3736 6.162e-17 85.0 2E8C8@1|root,332QW@2|Bacteria,2GVKT@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_1681371_4 326427.Cagg_1059 8.602e-62 217.0 COG0477@1|root,COG2814@2|Bacteria,2G7PX@200795|Chloroflexi,3765F@32061|Chloroflexia 32061|Chloroflexia EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_1687072_1 383372.Rcas_1157 8.248e-119 387.0 COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi,375CC@32061|Chloroflexia 32061|Chloroflexia C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N SJTD3_k127_1687072_0 357808.RoseRS_4401 7.502e-129 424.0 COG0477@1|root,COG2814@2|Bacteria,2G7AV@200795|Chloroflexi,3782X@32061|Chloroflexia 32061|Chloroflexia EGP PFAM major facilitator superfamily MFS_1 - - - ko:K08162 - - - - ko00000,ko02000 2.A.1.2.21 - - MFS_1 SJTD3_k127_1687072_7 1356854.N007_11050 7.341e-05 54.0 2EUC9@1|root,33MUN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_1687072_4 485913.Krac_5359 1.136e-34 135.0 COG1695@1|root,COG1695@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated - - - - - - - - - - - - PadR SJTD3_k127_1687072_5 204669.Acid345_2783 7.008e-26 110.0 COG3098@1|root,COG3098@2|Bacteria 2|Bacteria S single-species biofilm formation yqcC GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 3.5.1.28,5.1.3.13,5.4.99.26 ko:K01790,ko:K03806,ko:K06175 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000,ko01011,ko03016 - - - DUF446 SJTD3_k127_1687072_2 485913.Krac_7202 2.69e-97 332.0 COG0477@1|root,COG2814@2|Bacteria,2G8CV@200795|Chloroflexi 2|Bacteria EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1,MFS_3 SJTD3_k127_1687072_3 316274.Haur_2225 1.204e-38 151.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DUF664,DinB_2 SJTD3_k127_1687072_8 861299.J421_3786 0.000314 51.0 COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase SJTD3_k127_1697971_0 106370.Francci3_3077 2.371e-16 89.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4ERI4@85013|Frankiales 201174|Actinobacteria KLT Serine threonine protein kinase pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase SJTD3_k127_1698819_0 485913.Krac_6780 1.552e-117 387.0 COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi 200795|Chloroflexi C PFAM Luciferase-like - - 1.14.14.5 ko:K04091 ko00920,map00920 - R07210,R10206 RC01779,RC02556 ko00000,ko00001,ko01000 - - - Bac_luciferase SJTD3_k127_1698819_1 1313172.YM304_27830 3.216e-40 157.0 COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria 201174|Actinobacteria C Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase SJTD3_k127_1701911_3 485913.Krac_3442 7.162e-24 105.0 COG1233@1|root,COG1233@2|Bacteria 2|Bacteria Q all-trans-retinol 13,14-reductase activity - - - - - - - - - - - - Amino_oxidase,NAD_binding_8 SJTD3_k127_1701911_2 316274.Haur_0414 4.531e-43 166.0 COG2345@1|root,COG2345@2|Bacteria,2G8V0@200795|Chloroflexi,375MI@32061|Chloroflexia 32061|Chloroflexia K DeoR-like helix-turn-helix domain - - - - - - - - - - - - HTH_24,HTH_DeoR SJTD3_k127_1701911_1 575540.Isop_3226 5.869e-92 314.0 COG0396@1|root,COG0396@2|Bacteria,2IY5X@203682|Planctomycetes 203682|Planctomycetes O COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component - - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran SJTD3_k127_1701911_0 309801.trd_0379 2.648e-93 323.0 COG0719@1|root,COG0719@2|Bacteria,2G5S8@200795|Chloroflexi,27Y27@189775|Thermomicrobia 189775|Thermomicrobia O Uncharacterized protein family (UPF0051) - - - ko:K09015 - - - - ko00000 - - - UPF0051 SJTD3_k127_170699_2 316274.Haur_4465 5.453e-10 64.0 COG3307@1|root,COG3307@2|Bacteria,2G6B1@200795|Chloroflexi,375BP@32061|Chloroflexia 32061|Chloroflexia M PFAM O-antigen polymerase - - - - - - - - - - - - Wzy_C SJTD3_k127_170699_0 926560.KE387023_gene2647 8.913e-116 380.0 COG0596@1|root,COG0596@2|Bacteria,1WN2Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Transposase and inactivated derivatives - - - - - - - - - - - - - SJTD3_k127_170699_1 272134.KB731324_gene2611 1.893e-33 134.0 COG0246@1|root,COG0246@2|Bacteria,1G3KX@1117|Cyanobacteria,1HECE@1150|Oscillatoriales 1117|Cyanobacteria G Mannitol dehydrogenase Rossmann domain - - 1.1.1.67 ko:K00045 ko00051,map00051 - R00868 RC00085 ko00000,ko00001,ko01000 - - - Mannitol_dh,Mannitol_dh_C SJTD3_k127_1712379_1 1123322.KB904680_gene3371 1.485e-06 52.0 COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria 201174|Actinobacteria K cellulose binding - - - - - - - - - - - - - SJTD3_k127_1712379_0 383372.Rcas_1915 6.127e-38 150.0 COG1595@1|root,COG1595@2|Bacteria,2GB53@200795|Chloroflexi,377AG@32061|Chloroflexia 32061|Chloroflexia K RNA polymerase, sigma-24 subunit, ECF subfamily - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_171888_4 765420.OSCT_0805 7.373e-34 139.0 COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi,37660@32061|Chloroflexia 32061|Chloroflexia V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SJTD3_k127_171888_2 765420.OSCT_0806 9.783e-92 309.0 COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi,376XE@32061|Chloroflexia 32061|Chloroflexia V Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_171888_5 1521187.JPIM01000179_gene2365 2.295e-32 146.0 COG0845@1|root,COG1566@1|root,COG0845@2|Bacteria,COG1566@2|Bacteria,2G6RK@200795|Chloroflexi 200795|Chloroflexi M PFAM secretion protein HlyD family protein - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23 SJTD3_k127_171888_1 479434.Sthe_0314 1.176e-101 341.0 COG3285@1|root,COG3285@2|Bacteria,2GBDW@200795|Chloroflexi,27Z1A@189775|Thermomicrobia 189775|Thermomicrobia L dna ligase - - 6.5.1.1 ko:K01971 ko03450,map03450 - R00381 RC00005 ko00000,ko00001,ko01000,ko03400 - - - - SJTD3_k127_171888_6 1192034.CAP_4647 8.35e-27 119.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - 2.1.1.180 ko:K18846 - - - - ko00000,ko01000,ko01504,ko03009 - - - Methyltransf_11,Methyltransf_25 SJTD3_k127_171888_9 383372.Rcas_1659 0.0007709 51.0 COG3266@1|root,COG3266@2|Bacteria,2G9F4@200795|Chloroflexi,377QC@32061|Chloroflexia 32061|Chloroflexia S domain, Protein - - - - - - - - - - - - - SJTD3_k127_171888_7 383372.Rcas_4108 3.452e-25 111.0 COG1595@1|root,COG1595@2|Bacteria,2G9TD@200795|Chloroflexi 200795|Chloroflexi K RNA polymerase, sigma-24 subunit, ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2 SJTD3_k127_171888_0 479434.Sthe_3252 8.69e-113 373.0 COG2141@1|root,COG2141@2|Bacteria,2G87P@200795|Chloroflexi,27XPZ@189775|Thermomicrobia 200795|Chloroflexi C Luciferase-like monooxygenase - - 1.14.14.5 ko:K04091 ko00920,map00920 - R07210,R10206 RC01779,RC02556 ko00000,ko00001,ko01000 - - - Bac_luciferase SJTD3_k127_171888_3 485913.Krac_3470 4.462e-79 270.0 COG1272@1|root,COG1272@2|Bacteria,2G7B7@200795|Chloroflexi 200795|Chloroflexi S PFAM Hly-III family protein - - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII SJTD3_k127_171888_8 926569.ANT_30850 4.21e-22 105.0 COG0694@1|root,COG0694@2|Bacteria 2|Bacteria O iron-sulfur cluster assembly nfuA - - - - - - - - - - - NifU SJTD3_k127_1726627_1 649747.HMPREF0083_03630 1.406e-79 274.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli,26TYT@186822|Paenibacillaceae 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase SJTD3_k127_1726627_2 401526.TcarDRAFT_1564 1.11e-65 235.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4H2Y2@909932|Negativicutes 909932|Negativicutes E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE - 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_DH,Shikimate_dh_N SJTD3_k127_1726627_0 1232410.KI421416_gene2557 1.279e-110 369.0 COG0082@1|root,COG0082@2|Bacteria,1MU98@1224|Proteobacteria,42MF9@68525|delta/epsilon subdivisions,2WJ57@28221|Deltaproteobacteria,43U6V@69541|Desulfuromonadales 28221|Deltaproteobacteria E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0976 Chorismate_synt SJTD3_k127_1726627_3 1411123.JQNH01000001_gene3545 6.881e-14 78.0 COG0703@1|root,COG0703@2|Bacteria,1MUFJ@1224|Proteobacteria,2U76C@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK - 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI SJTD3_k127_1768753_1 1089550.ATTH01000001_gene501 1.197e-17 95.0 COG2357@1|root,COG2357@2|Bacteria,4NFMF@976|Bacteroidetes,1FJT2@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes S RelA SpoT domain protein - - - - - - - - - - - - GTA_TIM SJTD3_k127_1768753_0 479434.Sthe_0357 1.044e-50 194.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_1768753_2 680646.RMDY18_18830 5.875e-13 83.0 COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,1W8TR@1268|Micrococcaceae 201174|Actinobacteria O Subtilase family - - - - - - - - - - - - Big_3_5,PA,Peptidase_S8,SLH,fn3_5 SJTD3_k127_1780132_0 479434.Sthe_0669 2.134e-279 880.0 COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia 189775|Thermomicrobia L that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V SJTD3_k127_1780132_2 13035.Dacsa_0102 1.181e-25 107.0 COG1598@1|root,COG1598@2|Bacteria,1G9X3@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - HicB_lk_antitox SJTD3_k127_1780132_3 448385.sce0728 7.448e-22 98.0 2AVYW@1|root,31MT4@2|Bacteria,1PK41@1224|Proteobacteria,430FY@68525|delta/epsilon subdivisions,2WVR7@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_1780132_1 448385.sce0728 5.561e-32 127.0 2AVYW@1|root,31MT4@2|Bacteria,1PK41@1224|Proteobacteria,430FY@68525|delta/epsilon subdivisions,2WVR7@28221|Deltaproteobacteria 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_1780132_4 395963.Bind_2266 6.162e-10 70.0 COG0666@1|root,COG0666@2|Bacteria,1MZSX@1224|Proteobacteria,2UC99@28211|Alphaproteobacteria 28211|Alphaproteobacteria S response to abiotic stimulus - - - - - - - - - - - - Ank SJTD3_k127_1791855_0 1183438.GKIL_1369 4.059e-138 467.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - SBBP SJTD3_k127_1794158_0 1128421.JAGA01000002_gene789 6.053e-282 894.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2NPET@2323|unclassified Bacteria 2|Bacteria GT Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N SJTD3_k127_179668_0 997346.HMPREF9374_1437 3.448e-234 737.0 COG1506@1|root,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,4HAC0@91061|Bacilli 91061|Bacilli EU peptidase - - - - - - - - - - - - PD40,Peptidase_S9,Peptidase_S9_N SJTD3_k127_179668_1 909613.UO65_1308 9.421e-47 186.0 COG0477@1|root,COG2814@2|Bacteria,2I5F8@201174|Actinobacteria,4E5MI@85010|Pseudonocardiales 201174|Actinobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 SJTD3_k127_1816259_2 290397.Adeh_1286 4.861e-12 68.0 COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales 28221|Deltaproteobacteria K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_1816259_0 383372.Rcas_2175 1.653e-68 239.0 COG2191@1|root,COG2191@2|Bacteria,2G7H2@200795|Chloroflexi,376Q2@32061|Chloroflexia 32061|Chloroflexia C PFAM formylmethanofuran dehydrogenase, subunit E region - - 1.2.7.12 ko:K11261 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 M00567 R03015,R08060,R11743 RC00197,RC00323 ko00000,ko00001,ko00002,ko01000 - - - FmdE,zf-dskA_traR SJTD3_k127_1816259_1 479434.Sthe_1016 7.24e-41 159.0 COG0746@1|root,COG0746@2|Bacteria,2G786@200795|Chloroflexi,27Y9U@189775|Thermomicrobia 189775|Thermomicrobia H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor mobA - 2.7.7.77 ko:K03752 ko00790,ko01100,map00790,map01100 - R11581 - ko00000,ko00001,ko01000 - - - NTP_transf_3 SJTD3_k127_1825153_2 324602.Caur_3439 1.881e-08 67.0 COG1287@1|root,COG1287@2|Bacteria,2GA8N@200795|Chloroflexi,374X5@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_1825153_1 383372.Rcas_3443 1.933e-23 117.0 COG1287@1|root,COG1287@2|Bacteria,2GB49@200795|Chloroflexi,377W7@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - ko:K19168 - - - - ko00000,ko02048 - - - - SJTD3_k127_1825153_0 383372.Rcas_3043 4.284e-70 263.0 COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,376IX@32061|Chloroflexia 32061|Chloroflexia P Probably functions as a manganese efflux pump - - - - - - - - - - - - - SJTD3_k127_1827449_2 211165.AJLN01000116_gene3145 2.37e-15 78.0 COG0500@1|root,COG2226@2|Bacteria,1G9FG@1117|Cyanobacteria 1117|Cyanobacteria Q Methylase involved in ubiquinone menaquinone biosynthesis - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SJTD3_k127_1827449_0 1382306.JNIM01000001_gene471 2.82e-91 310.0 COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi 200795|Chloroflexi C PFAM Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_1827449_1 1382306.JNIM01000001_gene1569 3.854e-43 162.0 COG0520@1|root,COG0520@2|Bacteria,2G5W7@200795|Chloroflexi 200795|Chloroflexi E TIGRFAM cysteine desulfurase family protein - - - - - - - - - - - - Aminotran_5 SJTD3_k127_1838066_0 388051.AUFE01000046_gene2496 9.561e-239 743.0 COG0277@1|root,COG0277@2|Bacteria,1MUPW@1224|Proteobacteria,2VNG1@28216|Betaproteobacteria,1KH5I@119060|Burkholderiaceae 28216|Betaproteobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 SJTD3_k127_1838066_2 381666.H16_B1607 2.793e-210 691.0 COG3629@1|root,COG3899@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,1MUDT@1224|Proteobacteria,2VPH8@28216|Betaproteobacteria,1KCSE@119060|Burkholderiaceae 28216|Betaproteobacteria K Bacterial transcriptional activator domain - - - - - - - - - - - - AAA_16,BTAD SJTD3_k127_1838066_6 485913.Krac_10329 2.056e-06 54.0 COG1961@1|root,COG1961@2|Bacteria,2G7XN@200795|Chloroflexi 200795|Chloroflexi L Recombinase zinc beta ribbon domain - - - - - - - - - - - - Recombinase,Resolvase,Zn_ribbon_recom SJTD3_k127_1838066_5 1382356.JQMP01000001_gene1035 5.215e-07 51.0 COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi,27Y2X@189775|Thermomicrobia 189775|Thermomicrobia O Magnesium chelatase, subunit ChlI - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C SJTD3_k127_1838066_4 926569.ANT_28040 3.817e-78 299.0 COG1744@1|root,COG1744@2|Bacteria,2G6UB@200795|Chloroflexi 200795|Chloroflexi M PFAM basic membrane lipoprotein - - - ko:K07335 - - - - ko00000 - - - Bmp SJTD3_k127_1838066_1 2002.JOEQ01000016_gene7347 7.626e-225 758.0 COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4EG08@85012|Streptosporangiales 201174|Actinobacteria M WD40 repeats - - - - - - - - - - - - HTH_31,WD40 SJTD3_k127_1838066_3 926569.ANT_17670 1.712e-206 654.0 COG0606@1|root,COG0606@2|Bacteria,2G65P@200795|Chloroflexi 200795|Chloroflexi O PFAM magnesium chelatase ChlI subunit - - - ko:K07391 - - - - ko00000 - - - ChlI,Mg_chelatase,Mg_chelatase_C SJTD3_k127_184589_3 1123236.KB899391_gene3425 1.742e-08 67.0 COG0823@1|root,COG1228@1|root,COG0823@2|Bacteria,COG1228@2|Bacteria,1MX3A@1224|Proteobacteria,1RMQZ@1236|Gammaproteobacteria,4641W@72275|Alteromonadaceae 1236|Gammaproteobacteria QU COG0823 Periplasmic component of the Tol biopolymer transport system - - - - - - - - - - - - Amidohydro_1,PD40 SJTD3_k127_184589_2 1340434.AXVA01000003_gene1575 3.438e-28 134.0 COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,1V0AI@1239|Firmicutes,4HDZZ@91061|Bacilli,1ZEHB@1386|Bacillus 91061|Bacilli P protein, homolog of Cu resistance protein CopC ycnJ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K14166 - - - - ko00000,ko02000 - - - CopC,CopD,YtkA SJTD3_k127_184589_1 525904.Tter_1117 2.517e-66 239.0 COG3391@1|root,COG3391@2|Bacteria,2NQ7V@2323|unclassified Bacteria 2|Bacteria S Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Cytochrom_D1,Lactonase SJTD3_k127_1851886_1 309801.trd_A0768 1.179e-15 84.0 COG1540@1|root,COG1540@2|Bacteria,2G8DT@200795|Chloroflexi,27YX7@189775|Thermomicrobia 189775|Thermomicrobia S Belongs to the UPF0271 (lamB) family - - - ko:K07160 - - - - ko00000 - - - LamB_YcsF SJTD3_k127_1851886_0 1128421.JAGA01000003_gene3234 7.798e-164 546.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2NQSS@2323|unclassified Bacteria 2|Bacteria S Putative glutamine amidotransferase - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,GATase1_like,VWA,VWA_2,VWA_3 SJTD3_k127_1887798_2 1128421.JAGA01000002_gene389 2.4e-97 338.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 SJTD3_k127_1887798_1 1128421.JAGA01000004_gene2535 7.705e-98 334.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_2,Glyco_trans_1_4,Glyco_trans_4_4 SJTD3_k127_1887798_0 383372.Rcas_3891 2.126e-103 353.0 COG0438@1|root,COG0438@2|Bacteria,2GANK@200795|Chloroflexi,374UX@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_1887798_3 357808.RoseRS_0849 1.565e-21 98.0 COG2227@1|root,COG2227@2|Bacteria,2GAEK@200795|Chloroflexi,376X5@32061|Chloroflexia 32061|Chloroflexia H Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_1891440_0 479434.Sthe_2024 1.557e-193 614.0 COG0031@1|root,COG3620@1|root,COG0031@2|Bacteria,COG3620@2|Bacteria,2G698@200795|Chloroflexi,27YAJ@189775|Thermomicrobia 189775|Thermomicrobia E Cysteine synthase - - 2.5.1.47,4.2.1.22 ko:K01697,ko:K01738,ko:K12339 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021,M00035,M00338 R00891,R00897,R01290,R03132,R03601,R04859,R04942 RC00020,RC00056,RC00069,RC00256,RC00489,RC01246,RC02814,RC02821,RC02876 ko00000,ko00001,ko00002,ko01000 - - - PALP SJTD3_k127_1891440_2 357808.RoseRS_3930 8.858e-135 439.0 COG0045@1|root,COG0045@2|Bacteria,2G68A@200795|Chloroflexi,3758T@32061|Chloroflexia 32061|Chloroflexia F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit sucC - 6.2.1.5 ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - ATP-grasp_2,Ligase_CoA SJTD3_k127_1891440_1 1128421.JAGA01000003_gene3696 3.298e-188 605.0 COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria 2|Bacteria E Oligopeptidase F - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N SJTD3_k127_1922162_5 357808.RoseRS_3058 2.069e-33 138.0 COG1879@1|root,COG1879@2|Bacteria,2G8QP@200795|Chloroflexi 200795|Chloroflexi P Periplasmic binding protein domain - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_1922162_3 365046.Rta_07270 3.443e-101 344.0 COG1940@1|root,COG1940@2|Bacteria,1NFM0@1224|Proteobacteria,2WG1U@28216|Betaproteobacteria,4ABZX@80864|Comamonadaceae 28216|Betaproteobacteria GK PFAM ROK family protein - - - - - - - - - - - - ROK SJTD3_k127_1922162_1 383372.Rcas_2791 9.257e-155 497.0 COG0673@1|root,COG0673@2|Bacteria,2G7YW@200795|Chloroflexi 200795|Chloroflexi S Oxidoreductase family, C-terminal alpha/beta domain - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C SJTD3_k127_1922162_6 926560.KE387023_gene3849 3.598e-29 121.0 COG2844@1|root,COG2844@2|Bacteria 2|Bacteria O Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen glnD - 2.7.7.59 ko:K00990 ko02020,map02020 - - - ko00000,ko00001,ko01000 - - - ACT,GlnD_UR_UTase,HD,NTP_transf_2 SJTD3_k127_1922162_2 357808.RoseRS_1085 2.089e-136 441.0 COG1082@1|root,COG1082@2|Bacteria,2G6W6@200795|Chloroflexi 200795|Chloroflexi G PFAM Xylose isomerase domain protein TIM barrel - - - - - - - - - - - - AP_endonuc_2,AP_endonuc_2_N SJTD3_k127_1922162_0 1380347.JNII01000006_gene1411 1.564e-181 582.0 COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria,4EV8F@85013|Frankiales 201174|Actinobacteria E GMC oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3 SJTD3_k127_1924462_0 500153.JOEK01000001_gene4232 2.621e-41 162.0 COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_N SJTD3_k127_1924462_1 1108045.GORHZ_092_00180 3.666e-37 145.0 COG5485@1|root,COG5485@2|Bacteria,2HXSD@201174|Actinobacteria,4GGQV@85026|Gordoniaceae 201174|Actinobacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL SJTD3_k127_1924462_2 479434.Sthe_0331 3.686e-26 119.0 COG0671@1|root,COG0671@2|Bacteria,2G8YH@200795|Chloroflexi,27YK3@189775|Thermomicrobia 189775|Thermomicrobia I Acid phosphatase homologues - - - - - - - - - - - - PAP2 SJTD3_k127_1938167_0 309801.trd_1060 1.415e-158 512.0 COG2352@1|root,COG2352@2|Bacteria,2G62H@200795|Chloroflexi,27YW3@189775|Thermomicrobia 189775|Thermomicrobia C Phosphoenolpyruvate carboxylase - - 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase SJTD3_k127_194145_2 926550.CLDAP_19830 2.287e-119 390.0 COG1175@1|root,COG1175@2|Bacteria,2G80Q@200795|Chloroflexi 200795|Chloroflexi G PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SJTD3_k127_194145_1 1128421.JAGA01000002_gene985 5.633e-171 550.0 COG1653@1|root,COG1653@2|Bacteria,2NQQ6@2323|unclassified Bacteria 2|Bacteria G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 SJTD3_k127_194145_3 926550.CLDAP_19810 7.779e-86 296.0 COG1609@1|root,COG1609@2|Bacteria,2G87J@200795|Chloroflexi 200795|Chloroflexi K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 SJTD3_k127_194145_0 1128421.JAGA01000002_gene988 3.259e-221 715.0 COG1331@1|root,COG1331@2|Bacteria,2NPT4@2323|unclassified Bacteria 2|Bacteria O Highly conserved protein containing a thioredoxin domain - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - DUF4861 SJTD3_k127_194145_4 525904.Tter_0859 6.482e-39 150.0 COG2152@1|root,COG2152@2|Bacteria,2NPN0@2323|unclassified Bacteria 2|Bacteria G beta-1,4-mannooligosaccharide phosphorylase - - 2.4.1.339,2.4.1.340 ko:K20885 - - R11397,R11398 RC00049,RC02748 ko00000,ko01000 - GH130 - Glyco_hydro_130 SJTD3_k127_1955904_0 1408473.JHXO01000002_gene3967 2.522e-55 203.0 COG1335@1|root,COG1335@2|Bacteria,4NMQE@976|Bacteroidetes,2FSUI@200643|Bacteroidia 976|Bacteroidetes Q Isochorismatase family - - - - - - - - - - - - Isochorismatase SJTD3_k127_1955904_1 1127134.NOCYR_4712 2.682e-12 77.0 COG0204@1|root,COG0204@2|Bacteria,2IB9T@201174|Actinobacteria,4FUH6@85025|Nocardiaceae 201174|Actinobacteria I Phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase SJTD3_k127_1973_0 290397.Adeh_2304 8.315e-137 439.0 COG0243@1|root,COG0243@2|Bacteria,1NR6J@1224|Proteobacteria,42MYN@68525|delta/epsilon subdivisions,2WIND@28221|Deltaproteobacteria,2YUEV@29|Myxococcales 28221|Deltaproteobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.8.5.3,1.8.5.5 ko:K07306,ko:K08352 ko00920,ko01120,map00920,map01120 - R09501,R10149 RC02555,RC02823 ko00000,ko00001,ko01000,ko02000 5.A.3.3,5.A.3.5 - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_1973_1 644966.Tmar_1592 1.527e-27 117.0 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - - - - - - - - - - DUF5069,Lactamase_B,Rhodanese SJTD3_k127_1973_2 1455608.JDTH01000002_gene1599 8.625e-23 115.0 COG1520@1|root,arCOG02482@2157|Archaea,arCOG02492@2157|Archaea,2XZQY@28890|Euryarchaeota,23X43@183963|Halobacteria 183963|Halobacteria S Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat - - - - - - - - - - - - PQQ_2,PQQ_3 SJTD3_k127_1974974_0 1128421.JAGA01000002_gene1506 2.118e-126 434.0 COG1480@1|root,COG1480@2|Bacteria,2NP1K@2323|unclassified Bacteria 2|Bacteria S 7TM receptor with intracellular HD hydrolase yqfF - - ko:K07037 - - - - ko00000 - - - 7TM-7TMR_HD,7TMR-HDED,HD SJTD3_k127_1974974_1 1123252.ATZF01000001_gene970 2.081e-16 85.0 COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,4HIQP@91061|Bacilli,27C2F@186824|Thermoactinomycetaceae 91061|Bacilli S Yqey-like protein yqeY - - ko:K09117 - - - - ko00000 - - - YqeY SJTD3_k127_1979550_1 1380390.JIAT01000009_gene637 6.607e-16 81.0 COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4CTX9@84995|Rubrobacteria 201174|Actinobacteria KT helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,TPR_19 SJTD3_k127_1979550_0 67315.JOBD01000031_gene7230 6.143e-68 249.0 COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria 201174|Actinobacteria I COG3209 Rhs family protein - - - - - - - - - - - - PAP2 SJTD3_k127_1984334_1 1183438.GKIL_0525 2.493e-44 166.0 COG1451@1|root,COG1451@2|Bacteria,1G1B3@1117|Cyanobacteria 1117|Cyanobacteria S Protein of unknown function DUF45 - - - ko:K07043 - - - - ko00000 - - - DUF45 SJTD3_k127_1984334_0 479434.Sthe_1762 1.034e-83 308.0 COG1971@1|root,COG1971@2|Bacteria,2G8IE@200795|Chloroflexi,27YSN@189775|Thermomicrobia 189775|Thermomicrobia P Probably functions as a manganese efflux pump - - - - - - - - - - - - - SJTD3_k127_1990880_2 383372.Rcas_1295 8.89e-53 192.0 COG0500@1|root,COG2226@2|Bacteria,2G6T6@200795|Chloroflexi,375HK@32061|Chloroflexia 32061|Chloroflexia H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG - 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran SJTD3_k127_1990880_1 383372.Rcas_1392 1.846e-68 249.0 COG2344@1|root,COG2344@2|Bacteria,2G6EJ@200795|Chloroflexi,375EY@32061|Chloroflexia 32061|Chloroflexia K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N SJTD3_k127_1990880_0 926569.ANT_15320 1.604e-92 321.0 COG0285@1|root,COG0285@2|Bacteria,2G64M@200795|Chloroflexi 200795|Chloroflexi H PFAM cytoplasmic peptidoglycan synthetase domain protein folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - - Mur_ligase_C,Mur_ligase_M SJTD3_k127_2000682_9 1122919.KB905558_gene1272 9.87e-08 60.0 COG0622@1|root,COG0622@2|Bacteria 2|Bacteria S retrograde transport, endosome to Golgi - - - ko:K07095 - - - - ko00000 - - - DinB_2,Metallophos_2 SJTD3_k127_2000682_1 688269.Theth_1946 2.918e-110 373.0 COG0312@1|root,COG0312@2|Bacteria,2GDC4@200918|Thermotogae 200918|Thermotogae L modulator of DNA gyrase - - - ko:K03568 - - - - ko00000,ko01002 - - - PmbA_TldD SJTD3_k127_2000682_8 997346.HMPREF9374_0440 6.464e-37 147.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli,27C05@186824|Thermoactinomycetaceae 91061|Bacilli I Phosphate acyltransferases plsC - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase SJTD3_k127_2000682_7 292459.STH1497 1.279e-37 153.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,25HJP@186801|Clostridia 186801|Clostridia S Belongs to the CDS family cdsA - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 SJTD3_k127_2000682_4 3218.PP1S126_106V6.1 1.852e-44 169.0 COG0303@1|root,KOG2371@2759|Eukaryota,37MHI@33090|Viridiplantae,3G7K1@35493|Streptophyta 35493|Streptophyta H Molybdopterin biosynthesis protein - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008940,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009719,GO:0009725,GO:0009733,GO:0009734,GO:0009755,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0016491,GO:0016661,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0023052,GO:0030151,GO:0032324,GO:0032870,GO:0034641,GO:0036211,GO:0042040,GO:0042221,GO:0042278,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051716,GO:0055086,GO:0055114,GO:0061598,GO:0061599,GO:0065007,GO:0070566,GO:0070887,GO:0071310,GO:0071365,GO:0071495,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.75 ko:K15376 ko00790,ko01100,ko04727,map00790,map01100,map04727 - R09726,R09735 RC00002,RC03462 ko00000,ko00001,ko01000 - - - MoCF_biosynth,MoeA_C,MoeA_N SJTD3_k127_2000682_6 383372.Rcas_2959 1.943e-41 164.0 COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi,375JA@32061|Chloroflexia 32061|Chloroflexia M PFAM peptidase C60, sortase A and B - - - - - - - - - - - - Sortase SJTD3_k127_2000682_5 574087.Acear_0228 7.222e-43 171.0 COG2433@1|root,COG4585@1|root,COG2433@2|Bacteria,COG4585@2|Bacteria,1TQI3@1239|Firmicutes,249R9@186801|Clostridia,3WB8N@53433|Halanaerobiales 186801|Clostridia T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase degS - 2.7.13.3 ko:K07777 ko02020,map02020 M00478 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DegS,HATPase_c,HisKA_3 SJTD3_k127_2000682_2 479434.Sthe_1615 1.114e-97 323.0 COG2197@1|root,COG2197@2|Bacteria,2G6K0@200795|Chloroflexi,27Y3S@189775|Thermomicrobia 189775|Thermomicrobia K Two component transcriptional regulator, LuxR family - - - - - - - - - - - - GerE,Response_reg SJTD3_k127_2000682_0 765420.OSCT_2686 2.13e-198 630.0 COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi,374YV@32061|Chloroflexia 32061|Chloroflexia S PFAM ABC transporter related - - 3.6.3.17 ko:K02056 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran SJTD3_k127_2000682_3 765420.OSCT_1557 3.027e-92 311.0 COG1079@1|root,COG1079@2|Bacteria,2G6BT@200795|Chloroflexi,374T2@32061|Chloroflexia 32061|Chloroflexia S Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SJTD3_k127_2003164_0 324602.Caur_0353 6.992e-39 153.0 COG0406@1|root,COG0406@2|Bacteria,2G731@200795|Chloroflexi,37792@32061|Chloroflexia 32061|Chloroflexia G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 SJTD3_k127_2003164_1 211114.JOEF01000002_gene4011 2.019e-16 91.0 COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4DY2M@85010|Pseudonocardiales 201174|Actinobacteria K Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol mshD GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 ko:K15520 - - - - ko00000,ko01000 - - - Acetyltransf_1 SJTD3_k127_2003164_2 309801.trd_1027 9.192e-14 74.0 COG0142@1|root,COG0142@2|Bacteria,2G6IZ@200795|Chloroflexi,27XMM@189775|Thermomicrobia 189775|Thermomicrobia H Belongs to the FPP GGPP synthase family - - 2.5.1.90 ko:K02523 ko00900,ko01110,map00900,map01110 - R09248 RC00279 ko00000,ko00001,ko01000,ko01006 - - - polyprenyl_synt SJTD3_k127_2005942_1 926550.CLDAP_04570 1.547e-83 284.0 COG0003@1|root,COG0003@2|Bacteria,2G64V@200795|Chloroflexi 200795|Chloroflexi P PFAM Anion-transporting ATPase - - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase SJTD3_k127_2005942_0 316274.Haur_4672 1.46e-98 343.0 COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,376H6@32061|Chloroflexia 32061|Chloroflexia K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SJTD3_k127_2005942_2 1382356.JQMP01000004_gene51 1.117e-42 167.0 2C5T0@1|root,337HV@2|Bacteria,2G9CN@200795|Chloroflexi,27Y76@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - SJTD3_k127_2006675_0 1192034.CAP_1904 1.362e-179 569.0 COG1063@1|root,COG1063@2|Bacteria,1MW6Y@1224|Proteobacteria,42RN7@68525|delta/epsilon subdivisions,2WNNX@28221|Deltaproteobacteria,2YUI2@29|Myxococcales 28221|Deltaproteobacteria C Alcohol dehydrogenase GroES-like domain - - 1.1.1.14,1.2.1.46 ko:K00008,ko:K00148 ko00040,ko00051,ko00625,ko00680,ko01100,ko01120,ko01200,map00040,map00051,map00625,map00680,map01100,map01120,map01200 M00014 R00604,R00875,R01896 RC00085,RC00102,RC00188 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N SJTD3_k127_2006675_2 644966.Tmar_1733 2.592e-67 234.0 COG1670@1|root,COG1670@2|Bacteria,1V2FI@1239|Firmicutes,25B0M@186801|Clostridia,3WDSJ@538999|Clostridiales incertae sedis 186801|Clostridia J Acetyltransferase (GNAT) domain - - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 SJTD3_k127_2006675_1 861299.J421_1669 3.303e-126 411.0 COG0623@1|root,COG0623@2|Bacteria,1ZTGW@142182|Gemmatimonadetes 142182|Gemmatimonadetes I Enoyl-(Acyl carrier protein) reductase - - 1.3.1.10,1.3.1.9 ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 M00083,M00572 R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671 RC00052,RC00076,RC00120 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SJTD3_k127_2006675_3 266117.Rxyl_2778 1.437e-54 195.0 COG1528@1|root,COG1528@2|Bacteria,2IIT3@201174|Actinobacteria,4CQMY@84995|Rubrobacteria 84995|Rubrobacteria P Ferritin-like domain - - 1.16.3.2 ko:K02217 - - - - ko00000,ko01000 - - - Ferritin SJTD3_k127_2006675_4 670487.Ocepr_0155 7.125e-20 91.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - - - - - - - - - - - Methyltransf_25 SJTD3_k127_2006813_4 247490.KSU1_D0514 1.988e-09 69.0 COG3055@1|root,COG3204@1|root,COG3055@2|Bacteria,COG3204@2|Bacteria 2|Bacteria L pilus organization - - - ko:K02674,ko:K07004 - - - - ko00000,ko02035,ko02044 - - - Big_5,Exo_endo_phos,He_PIG,HemolysinCabind,LTD,Laminin_G_3,Malectin,PA14 SJTD3_k127_2006813_1 56780.SYN_01134 6.321e-137 454.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process cps2I - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C SJTD3_k127_2006813_2 504472.Slin_2959 4.969e-97 334.0 28NTY@1|root,2ZBSE@2|Bacteria,4NNC3@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SJTD3_k127_2006813_0 56780.SYN_01139 2.315e-139 462.0 COG0125@1|root,COG0125@2|Bacteria,1RA0K@1224|Proteobacteria 1224|Proteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - - - - - - - - - - - SJTD3_k127_2009786_0 1068980.ARVW01000001_gene6367 4.418e-156 509.0 COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DYQ4@85010|Pseudonocardiales 201174|Actinobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_2009786_2 215803.DB30_0234 2.784e-60 222.0 COG1846@1|root,COG1846@2|Bacteria,1N6YD@1224|Proteobacteria,433TH@68525|delta/epsilon subdivisions,2X3E9@28221|Deltaproteobacteria,2YVPE@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR SJTD3_k127_2009786_1 1128421.JAGA01000002_gene906 1.588e-130 430.0 COG0525@1|root,COG0525@2|Bacteria,2NNKR@2323|unclassified Bacteria 2|Bacteria J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS - 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 SJTD3_k127_201133_0 42256.RradSPS_3058 2.468e-103 349.0 COG1503@1|root,COG1503@2|Bacteria 2|Bacteria J translation release factor activity - - - - - - - - - - - - - SJTD3_k127_201133_1 313606.M23134_00104 2.205e-06 50.0 COG2050@1|root,COG2050@2|Bacteria,4NUVZ@976|Bacteroidetes 976|Bacteroidetes Q Thioesterase superfamily - - - - - - - - - - - - 4HBT SJTD3_k127_2011864_0 7739.XP_002601589.1 3.072e-08 64.0 KOG4441@1|root,KOG4441@2759|Eukaryota,3AJ5U@33154|Opisthokonta,3BYTD@33208|Metazoa,3DDMA@33213|Bilateria 33208|Metazoa T protein ubiquitination - - - ko:K10447 ko04120,map04120 - - - ko00000,ko00001,ko04121 - - - BACK,BTB SJTD3_k127_2012069_3 525904.Tter_1683 2.013e-28 130.0 COG0515@1|root,COG3103@1|root,COG0515@2|Bacteria,COG4991@2|Bacteria,2NQNE@2323|unclassified Bacteria 2|Bacteria T Serine threonine protein kinase - - 2.7.11.1 ko:K07282,ko:K12132,ko:K15539 - - - - ko00000,ko01000,ko01001 - - - Pkinase,SH3_3,SH3_4 SJTD3_k127_2012069_1 1382356.JQMP01000004_gene331 1.822e-85 288.0 COG0569@1|root,COG0569@2|Bacteria,2G6J8@200795|Chloroflexi,27XTU@189775|Thermomicrobia 189775|Thermomicrobia P TrkA-C domain - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N SJTD3_k127_2012069_2 1382306.JNIM01000001_gene386 7.154e-43 164.0 COG0569@1|root,COG0569@2|Bacteria,2G71A@200795|Chloroflexi 200795|Chloroflexi C PFAM TrkA-N domain protein - - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_N SJTD3_k127_2012069_7 525904.Tter_1706 8.072e-19 93.0 COG0589@1|root,COG0589@2|Bacteria 2|Bacteria T AMP binding - - - - - - - - - - - - Usp SJTD3_k127_2012069_0 357808.RoseRS_1605 9.101e-308 971.0 COG0466@1|root,COG0466@2|Bacteria,2G5TZ@200795|Chloroflexi,374Z8@32061|Chloroflexia 32061|Chloroflexia O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - 3.4.21.53 ko:K01338 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - AAA,LON_substr_bdg,Lon_C SJTD3_k127_2012069_8 713587.THITH_01480 0.0007162 52.0 COG0484@1|root,COG0484@2|Bacteria,1MUZ4@1224|Proteobacteria,1RP09@1236|Gammaproteobacteria,1WX0B@135613|Chromatiales 135613|Chromatiales O heat shock protein DnaJ - - - ko:K05516 - - - - ko00000,ko03036,ko03110 - - - DnaJ,DnaJ_C SJTD3_k127_2012069_4 1051632.TPY_1185 2.505e-27 122.0 COG0526@1|root,COG0526@2|Bacteria,1V7JP@1239|Firmicutes,25ET7@186801|Clostridia 186801|Clostridia CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - AhpC-TSA,Redoxin SJTD3_k127_2012069_6 1183438.GKIL_2043 3.259e-25 118.0 COG4244@1|root,COG4244@2|Bacteria,1G0PC@1117|Cyanobacteria 1117|Cyanobacteria S Membrane - - - - - - - - - - - - - SJTD3_k127_2012069_5 765420.OSCT_1906 1.03e-26 114.0 COG2340@1|root,COG2340@2|Bacteria 2|Bacteria S peptidase inhibitor activity - - - - - - - - - - - - CAP SJTD3_k127_2021743_0 439292.Bsel_0850 2.246e-18 101.0 COG1404@1|root,COG2333@1|root,COG4257@1|root,COG1404@2|Bacteria,COG2333@2|Bacteria,COG4257@2|Bacteria 2|Bacteria V antibiotic catabolic process - - 3.1.31.1,3.4.21.66 ko:K01174,ko:K02238,ko:K08651,ko:K13277,ko:K20276,ko:K20486 ko02020,ko02024,map02020,map02024 M00429 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko02044,ko03110 3.A.11.1,3.A.11.2 - - DUF5011,Peptidase_S8 SJTD3_k127_2021743_1 945713.IALB_1078 2.05e-14 88.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - BNR,PSII_BNR SJTD3_k127_2022846_2 485913.Krac_4323 9.814e-35 141.0 COG0673@1|root,COG0673@2|Bacteria,2G6E7@200795|Chloroflexi 200795|Chloroflexi S Oxidoreductase family, NAD-binding Rossmann fold - - 1.1.1.18,1.1.1.369 ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA,GFO_IDH_MocA_C SJTD3_k127_2022846_1 485913.Krac_4322 1.51e-140 453.0 COG1082@1|root,COG1082@2|Bacteria,2G613@200795|Chloroflexi 200795|Chloroflexi G Xylose isomerase-like TIM barrel - - 4.2.1.44 ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R02782,R05659 RC00782,RC01448 ko00000,ko00001,ko01000 - - - AP_endonuc_2 SJTD3_k127_2022846_0 485913.Krac_4320 4.825e-169 535.0 COG3962@1|root,COG3962@2|Bacteria,2G68S@200795|Chloroflexi 200795|Chloroflexi E Thiamine pyrophosphate enzyme, central domain - - 3.7.1.22 ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 - R08603 RC02331 ko00000,ko00001,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N SJTD3_k127_2034646_6 1262914.BN533_00511 2.055e-07 54.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4H2A6@909932|Negativicutes 909932|Negativicutes L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH SJTD3_k127_2034646_2 479434.Sthe_0524 2.264e-85 297.0 COG0006@1|root,COG0006@2|Bacteria,2G6AH@200795|Chloroflexi,27XJK@189775|Thermomicrobia 189775|Thermomicrobia E Creatinase/Prolidase N-terminal domain - - - - - - - - - - - - Creatinase_N,Peptidase_M24 SJTD3_k127_2034646_4 525904.Tter_1235 2.539e-37 157.0 COG0628@1|root,COG0628@2|Bacteria,2NPIB@2323|unclassified Bacteria 2|Bacteria S AI-2E family transporter yueF GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - ko:K03548 - - - - ko00000,ko02000 2.A.86.1 - - AI-2E_transport SJTD3_k127_2034646_5 1173026.Glo7428_4200 1.368e-33 145.0 COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1FZWU@1117|Cyanobacteria 1117|Cyanobacteria T Diguanylate cyclase with PAS PAC and GAF sensors - - - - - - - - - - - - CHASE3,GAF,GAF_2,GAF_3,GGDEF,PAS,PAS_3,PAS_9 SJTD3_k127_2034646_0 324602.Caur_2352 3.014e-145 475.0 COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria 2|Bacteria CH Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7' pds - 1.17.8.1,1.3.3.15,1.3.3.4,1.3.5.5,1.3.5.6 ko:K00231,ko:K00514,ko:K02293,ko:K09879,ko:K21677 ko00860,ko00906,ko01100,ko01110,map00860,map00906,map01100,map01110 M00097,M00121 R03222,R04178,R04786,R04787,R04798,R04800,R07510,R07511,R07541,R07560,R07857,R07858,R09652,R09653,R09654,R09656,R09658 RC00885,RC01214,RC01901,RC01958,RC01959,RC01965,RC03092,RC03093 ko00000,ko00001,ko00002,ko01000 - - - Amino_oxidase SJTD3_k127_2034646_1 1521187.JPIM01000001_gene863 7.979e-94 323.0 COG1562@1|root,COG1562@2|Bacteria,2G6KD@200795|Chloroflexi,3755P@32061|Chloroflexia 32061|Chloroflexia I PFAM Squalene phytoene synthase - - 2.5.1.32,2.5.1.99 ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 M00097 R02065,R04218,R07270,R10177 RC00362,RC01101,RC02869 ko00000,ko00001,ko00002,ko01000,ko01006 - - - SQS_PSY SJTD3_k127_2034646_3 675635.Psed_2039 1.963e-40 159.0 COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4E2NI@85010|Pseudonocardiales 201174|Actinobacteria K Sigma-70, region 4 sigK - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 SJTD3_k127_2040181_1 357808.RoseRS_2358 2.367e-62 231.0 COG1525@1|root,COG1572@1|root,COG1525@2|Bacteria,COG1572@2|Bacteria,2G86R@200795|Chloroflexi,3757A@32061|Chloroflexia 32061|Chloroflexia G PFAM peptidase domain protein - - - - - - - - - - - - NPCBM_assoc,PPC SJTD3_k127_2040181_0 309801.trd_0354 1.723e-146 478.0 COG0621@1|root,COG0621@2|Bacteria,2G5QK@200795|Chloroflexi,27Y2T@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine miaB - 2.8.4.3 ko:K06168 - - R10645,R10646,R10647 RC00003,RC00980,RC03221,RC03222 ko00000,ko01000,ko03016 - - - Radical_SAM,TRAM,UPF0004 SJTD3_k127_2040181_2 316274.Haur_1045 6.009e-55 203.0 COG0457@1|root,COG0457@2|Bacteria,2G6Q2@200795|Chloroflexi,375HW@32061|Chloroflexia 32061|Chloroflexia S Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_1,TPR_2 SJTD3_k127_2046185_0 1128421.JAGA01000002_gene158 1.507e-56 200.0 COG4608@1|root,COG4608@2|Bacteria 2|Bacteria P Belongs to the ABC transporter superfamily MA20_20675 - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY SJTD3_k127_2046185_2 1284352.AOIG01000018_gene4312 2.093e-08 63.0 28NII@1|root,2ZBJY@2|Bacteria,1V8N9@1239|Firmicutes,4HU2N@91061|Bacilli,26XNJ@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - MOSC SJTD3_k127_2046185_1 309801.trd_1557 2.822e-46 169.0 COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi,27XSZ@189775|Thermomicrobia 189775|Thermomicrobia E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N SJTD3_k127_2050339_3 525904.Tter_1036 2.806e-08 58.0 COG4745@1|root,COG4745@2|Bacteria,2NQAP@2323|unclassified Bacteria 2|Bacteria O Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_2050339_0 479434.Sthe_1860 6.645e-95 347.0 COG4745@1|root,COG4745@2|Bacteria,2G6HI@200795|Chloroflexi,27XK8@189775|Thermomicrobia 189775|Thermomicrobia O Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_2050339_1 485913.Krac_7311 3.569e-72 256.0 COG3021@1|root,COG3021@2|Bacteria,2G9DW@200795|Chloroflexi 200795|Chloroflexi S PFAM Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos SJTD3_k127_2050339_2 1125863.JAFN01000001_gene1637 3.475e-50 191.0 COG0389@1|root,COG0389@2|Bacteria,1MUUH@1224|Proteobacteria,42NGG@68525|delta/epsilon subdivisions,2WIVT@28221|Deltaproteobacteria 28221|Deltaproteobacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB - 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH SJTD3_k127_2061978_1 926569.ANT_30520 1.077e-99 341.0 COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi 200795|Chloroflexi G Belongs to the glycosyl hydrolase 13 family - - - - - - - - - - - - Alpha-amylase,Alpha-amylase_N,Big_5,Malt_amylase_C SJTD3_k127_2061978_7 82654.Pse7367_2500 1.316e-08 64.0 COG3881@1|root,COG3881@2|Bacteria,1GPYA@1117|Cyanobacteria,1HHVS@1150|Oscillatoriales 1117|Cyanobacteria S PRC-barrel domain - - - - - - - - - - - - PRC SJTD3_k127_2061978_2 402777.KB235903_gene1332 2.21e-59 212.0 COG1279@1|root,COG1279@2|Bacteria,1GQJ3@1117|Cyanobacteria,1HHX6@1150|Oscillatoriales 1117|Cyanobacteria S LysE type translocator - - - - - - - - - - - - LysE SJTD3_k127_2061978_0 266117.Rxyl_2540 1.045e-242 770.0 COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CPJ8@84995|Rubrobacteria 84995|Rubrobacteria O Protein of unknown function, DUF255 - - - ko:K06888 - - - - ko00000 - - - GlcNAc_2-epim,Thioredox_DsbH SJTD3_k127_2061978_3 1519464.HY22_02935 2.625e-49 182.0 COG0454@1|root,COG0456@2|Bacteria,1FF9G@1090|Chlorobi 1090|Chlorobi K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_2061978_4 1382356.JQMP01000003_gene1637 1.649e-39 169.0 COG0726@1|root,COG0726@2|Bacteria,2GA3J@200795|Chloroflexi,27Z0S@189775|Thermomicrobia 189775|Thermomicrobia G Polysaccharide deacetylase - - - - - - - - - - - - Polysacc_deac_1 SJTD3_k127_2061978_5 1173264.KI913949_gene2270 8.468e-26 125.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,1G05Y@1117|Cyanobacteria,1H6X5@1150|Oscillatoriales 1117|Cyanobacteria S Belongs to the peptidase M50B family - GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - ko:K06402 - - - - ko00000,ko01000,ko01002 - - - CBS,Peptidase_M50,Peptidase_M50B SJTD3_k127_2061978_6 525904.Tter_0632 7.185e-20 92.0 COG0699@1|root,COG0699@2|Bacteria,2NQN2@2323|unclassified Bacteria 2|Bacteria S Dynamin family - - - - - - - - - - - - Dynamin_N SJTD3_k127_207242_0 1033734.CAET01000006_gene3897 2.571e-143 471.0 COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,4HA0U@91061|Bacilli,1ZCPV@1386|Bacillus 91061|Bacilli G Bacterial extracellular solute-binding protein - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 SJTD3_k127_207242_2 1122915.AUGY01000044_gene7533 2.896e-105 349.0 COG1175@1|root,COG1175@2|Bacteria,1V109@1239|Firmicutes,4HC5A@91061|Bacilli,26UKR@186822|Paenibacillaceae 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - - - ko:K02025 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SJTD3_k127_207242_3 1033743.CAES01000015_gene2268 3.927e-98 329.0 COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,4HDNH@91061|Bacilli,26VJR@186822|Paenibacillaceae 91061|Bacilli G Binding-protein-dependent transport system inner membrane component - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SJTD3_k127_207242_1 1033734.CAET01000006_gene3895 1.741e-108 361.0 COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,4HCC1@91061|Bacilli,1ZRDP@1386|Bacillus 91061|Bacilli E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases gutB - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N SJTD3_k127_207242_4 1033734.CAET01000006_gene3901 4.606e-87 291.0 COG0269@1|root,COG0269@2|Bacteria,1TQ55@1239|Firmicutes,4HBMT@91061|Bacilli,1ZBDI@1386|Bacillus 91061|Bacilli G 3-hexulose-6-phosphate synthase hxlA GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase SJTD3_k127_2072699_0 644966.Tmar_0772 2.982e-114 383.0 COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia 186801|Clostridia T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA SJTD3_k127_2076516_4 485913.Krac_8896 2.561e-23 108.0 COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi 2|Bacteria S SPTR D1C1B9 DinB family protein dinB - - - - - - - - - - - DUF664,DinB SJTD3_k127_2076516_2 479434.Sthe_3161 1.86e-35 145.0 COG0634@1|root,COG0634@2|Bacteria,2G6HX@200795|Chloroflexi,27XU9@189775|Thermomicrobia 189775|Thermomicrobia F Phosphoribosyl transferase domain - - 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran SJTD3_k127_2076516_0 525904.Tter_0033 1.463e-53 194.0 COG0634@1|root,COG0634@2|Bacteria,2NPER@2323|unclassified Bacteria 2|Bacteria F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000 - - - Pribosyltran SJTD3_k127_2076516_6 526225.Gobs_4444 2.443e-15 90.0 COG5305@1|root,COG5305@2|Bacteria,2HTG8@201174|Actinobacteria,4ESH8@85013|Frankiales 201174|Actinobacteria S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_2076516_3 671143.DAMO_1513 9.374e-24 110.0 COG3415@1|root,COG3415@2|Bacteria,2NPY9@2323|unclassified Bacteria 2|Bacteria L Protein of unknown function (DUF3105) - - - - - - - - - - - - DDE_Tnp_ISAZ013,DUF3105,HTH_Tnp_IS630 SJTD3_k127_2076516_1 765420.OSCT_1906 8.094e-48 189.0 COG2340@1|root,COG2340@2|Bacteria 2|Bacteria S peptidase inhibitor activity - - - - - - - - - - - - CAP SJTD3_k127_2076516_5 313628.LNTAR_16077 5.513e-18 98.0 COG0749@1|root,COG0749@2|Bacteria 2|Bacteria L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1 SJTD3_k127_2076658_1 378806.STAUR_7738 3.321e-92 336.0 COG2866@1|root,COG2866@2|Bacteria,1PFUZ@1224|Proteobacteria,43AHH@68525|delta/epsilon subdivisions,2X5XP@28221|Deltaproteobacteria,2YYQC@29|Myxococcales 28221|Deltaproteobacteria E Zn_pept - - - - - - - - - - - - Peptidase_M14 SJTD3_k127_2076658_4 926550.CLDAP_23690 2.466e-36 143.0 COG1765@1|root,COG1765@2|Bacteria,2G6Y1@200795|Chloroflexi 200795|Chloroflexi O PFAM OsmC family protein - - - ko:K07397 - - - - ko00000 - - - OsmC SJTD3_k127_2076658_2 743718.Isova_0318 5.953e-78 283.0 COG4932@1|root,COG4932@2|Bacteria,2IFAA@201174|Actinobacteria 201174|Actinobacteria M domain protein - - - - - - - - - - - - - SJTD3_k127_2076658_3 1123024.AUII01000049_gene3646 7.957e-78 272.0 COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria 201174|Actinobacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - 1.14.14.5 ko:K04091 ko00920,map00920 - R07210,R10206 RC01779,RC02556 ko00000,ko00001,ko01000 - - - Bac_luciferase SJTD3_k127_2076658_0 1128421.JAGA01000003_gene3542 2.353e-111 368.0 COG1233@1|root,COG1233@2|Bacteria,2NQPV@2323|unclassified Bacteria 2|Bacteria Q Thi4 family crtO - - - - - - - - - - - Amino_oxidase,NAD_binding_8 SJTD3_k127_208256_0 525904.Tter_1578 3.95e-83 285.0 COG0803@1|root,COG0803@2|Bacteria,2NPJM@2323|unclassified Bacteria 2|Bacteria P Zinc-uptake complex component A periplasmic znuA - - ko:K09815,ko:K15727 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5,8.A.1.2.1 - - ZnuA SJTD3_k127_208256_1 1089548.KI783301_gene1459 4.159e-75 261.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli,3WFY6@539002|Bacillales incertae sedis 91061|Bacilli P ATPases associated with a variety of cellular activities zurA - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - - ABC_tran SJTD3_k127_208256_2 1262914.BN533_01771 6.159e-68 240.0 COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4H2U7@909932|Negativicutes 909932|Negativicutes P ABC 3 transport family - - - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 SJTD3_k127_208256_3 479434.Sthe_1534 1.285e-49 179.0 COG0599@1|root,COG0599@2|Bacteria,2GA0S@200795|Chloroflexi,27YG5@189775|Thermomicrobia 189775|Thermomicrobia O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - - - - - - - - - - CMD SJTD3_k127_208256_4 326427.Cagg_2442 1.674e-45 168.0 COG1232@1|root,COG1232@2|Bacteria,2G7T7@200795|Chloroflexi,3764F@32061|Chloroflexia 32061|Chloroflexia H PFAM amine oxidase - - - - - - - - - - - - Amino_oxidase SJTD3_k127_2082611_0 330084.JNYZ01000038_gene4144 2.63e-99 346.0 COG2025@1|root,COG2086@1|root,COG2025@2|Bacteria,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4E0JQ@85010|Pseudonocardiales 201174|Actinobacteria C Electron transfer flavoprotein - - - ko:K03521 - - - - ko00000 - - - ETF SJTD3_k127_2082611_1 525904.Tter_1099 4.544e-57 216.0 COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - - SJTD3_k127_2082611_2 1128421.JAGA01000002_gene226 3.034e-54 204.0 COG1657@1|root,COG1657@2|Bacteria 2|Bacteria I PFAM Prenyltransferase squalene oxidase - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - Pec_lyase,Prenyltrans,SQHop_cyclase_C SJTD3_k127_2090763_0 697282.Mettu_0616 1.562e-94 314.0 COG0446@1|root,COG0446@2|Bacteria,1NR3M@1224|Proteobacteria,1RN6P@1236|Gammaproteobacteria,1XEW5@135618|Methylococcales 135618|Methylococcales C Apoptosis-inducing factor, mitochondrion-associated, C-term - - - - - - - - - - - - AIF_C,Pyr_redox_2 SJTD3_k127_2090763_1 1463926.JOCA01000002_gene5637 6.296e-87 292.0 COG0302@1|root,COG0302@2|Bacteria,2H2JE@201174|Actinobacteria 201174|Actinobacteria H GTP cyclohydrolase I - - - - - - - - - - - - GTP_cyclohydroI SJTD3_k127_2090763_2 485913.Krac_11704 6.984e-59 216.0 COG1985@1|root,COG1985@2|Bacteria,2G97Y@200795|Chloroflexi 200795|Chloroflexi H RibD C-terminal domain - - - - - - - - - - - - RibD_C SJTD3_k127_2090763_4 596323.HMPREF0554_0948 6.928e-06 55.0 COG1225@1|root,COG1225@2|Bacteria 2|Bacteria O peroxiredoxin activity bcp GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SJTD3_k127_2090763_3 706587.Desti_4798 1.513e-47 173.0 COG1809@1|root,COG1809@2|Bacteria,1MUQY@1224|Proteobacteria 1224|Proteobacteria S (2R)-phospho-3-sulfolactate synthase (ComA) - - - - - - - - - - - - ComA SJTD3_k127_209372_3 1173025.GEI7407_1455 4.61e-20 94.0 COG0266@1|root,COG0266@2|Bacteria,1G22A@1117|Cyanobacteria,1HE9N@1150|Oscillatoriales 1117|Cyanobacteria L Formamidopyrimidine-DNA glycosylase N-terminal domain - - 4.2.99.18 ko:K05522 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS SJTD3_k127_209372_0 479434.Sthe_1845 2.252e-133 441.0 COG1508@1|root,COG1508@2|Bacteria,2G5VM@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM RNA polymerase sigma-54 factor, RpoN - - - ko:K03092 ko02020,ko05111,map02020,map05111 - - - ko00000,ko00001,ko03021 - - - Sigma54_AID,Sigma54_CBD,Sigma54_DBD SJTD3_k127_209372_2 926550.CLDAP_39000 3.338e-32 134.0 COG1595@1|root,COG1595@2|Bacteria,2G6X7@200795|Chloroflexi 200795|Chloroflexi K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4 SJTD3_k127_209372_1 743719.PaelaDRAFT_0941 5.206e-67 240.0 COG1266@1|root,COG1266@2|Bacteria,1TVK4@1239|Firmicutes,4I3C3@91061|Bacilli,273YG@186822|Paenibacillaceae 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - - SJTD3_k127_210915_3 387631.Asulf_01959 2.788e-11 70.0 COG0025@1|root,arCOG01961@2157|Archaea,2XVSR@28890|Euryarchaeota,246UN@183980|Archaeoglobi 183980|Archaeoglobi P NhaP-type Na H and K H - - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger SJTD3_k127_210915_0 1449063.JMLS01000005_gene3292 7.115e-118 397.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4HAIC@91061|Bacilli,26RUX@186822|Paenibacillaceae 91061|Bacilli P Arsenical pump membrane protein - - - ko:K03893 - - - - ko00000,ko02000 2.A.45.1,3.A.4.1 - - CitMHS SJTD3_k127_210915_1 525904.Tter_1268 6.655e-89 310.0 COG0793@1|root,COG0793@2|Bacteria,2NNVZ@2323|unclassified Bacteria 2|Bacteria M Belongs to the peptidase S41A family prc - 3.4.21.102 ko:K03797 - - - - ko00000,ko01000,ko01002 - - - Cu_amine_oxidN1,PDZ,PDZ_2,Peptidase_S41 SJTD3_k127_210915_2 345341.KUTG_08092 5.735e-62 228.0 COG1502@1|root,COG1502@2|Bacteria 2|Bacteria I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol - - - - - - - - - - - - PLDc_2 SJTD3_k127_2129855_4 316274.Haur_0255 5.52e-30 135.0 COG5022@1|root,COG5022@2|Bacteria,2GBHX@200795|Chloroflexi,37800@32061|Chloroflexia 32061|Chloroflexia Z LysM domain - - - - - - - - - - - - - SJTD3_k127_2129855_1 765420.OSCT_0735 2.122e-53 201.0 COG1668@1|root,COG1668@2|Bacteria,2GBIJ@200795|Chloroflexi,3768Z@32061|Chloroflexia 32061|Chloroflexia CP ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_2,ABC2_membrane_3 SJTD3_k127_2129855_0 1128421.JAGA01000002_gene169 4.918e-105 354.0 COG1131@1|root,COG1131@2|Bacteria,2NNKB@2323|unclassified Bacteria 2|Bacteria V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SJTD3_k127_2129855_2 765420.OSCT_0422 1.128e-49 203.0 COG0318@1|root,COG0318@2|Bacteria,2GBKJ@200795|Chloroflexi,3781K@32061|Chloroflexia 32061|Chloroflexia IQ PFAM AMP-dependent synthetase and ligase - - - - - - - - - - - - - SJTD3_k127_2129855_3 1128421.JAGA01000002_gene171 9.183e-32 140.0 COG3428@1|root,COG3428@2|Bacteria,2NS34@2323|unclassified Bacteria 2|Bacteria S Bacterial PH domain - - - ko:K08981 - - - - ko00000 - - - PASTA,bPH_2 SJTD3_k127_2135259_2 1128421.JAGA01000002_gene1964 8.968e-58 206.0 COG1595@1|root,COG1595@2|Bacteria,2NR5Q@2323|unclassified Bacteria 2|Bacteria K RNA polymerase sigma factor - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2,zf-HC2 SJTD3_k127_2135259_0 1123024.AUII01000001_gene3014 3.653e-68 254.0 COG0438@1|root,COG1215@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,2GNYT@201174|Actinobacteria,4ECH1@85010|Pseudonocardiales 201174|Actinobacteria M Glycosyltransferase like family 2 dpm - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2,GtrA SJTD3_k127_2135259_1 1246995.AFR_38655 1.506e-67 244.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_2135259_3 1197706.AKKK01000022_gene2222 1.583e-18 99.0 COG1874@1|root,COG1874@2|Bacteria,2I2ZB@201174|Actinobacteria 201174|Actinobacteria G Beta-galactosidase - - - - - - - - - - - - Glyco_hydro_42 SJTD3_k127_2135259_4 357808.RoseRS_0664 2.32e-17 87.0 COG1404@1|root,COG1404@2|Bacteria,2G7HM@200795|Chloroflexi,375CA@32061|Chloroflexia 32061|Chloroflexia M PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - Peptidase_S8 SJTD3_k127_2139649_0 1521187.JPIM01000020_gene218 1.782e-78 274.0 COG0438@1|root,COG0438@2|Bacteria,2GB6N@200795|Chloroflexi,37545@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_2139649_1 765420.OSCT_1276 1.4e-26 117.0 COG0297@1|root,COG0297@2|Bacteria,2GBMJ@200795|Chloroflexi,3782H@32061|Chloroflexia 32061|Chloroflexia H Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_trans_4_4,Glycos_transf_1 SJTD3_k127_2139649_2 765420.OSCT_1276 2.945e-10 62.0 COG0297@1|root,COG0297@2|Bacteria,2GBMJ@200795|Chloroflexi,3782H@32061|Chloroflexia 32061|Chloroflexia H Glycosyl transferase 4-like - - - - - - - - - - - - Glyco_trans_4_4,Glycos_transf_1 SJTD3_k127_2146184_0 479434.Sthe_0963 1.447e-143 484.0 COG0577@1|root,COG0577@2|Bacteria,2G68F@200795|Chloroflexi,27Y16@189775|Thermomicrobia 189775|Thermomicrobia V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SJTD3_k127_2146184_1 357808.RoseRS_4067 9.346e-46 189.0 COG0845@1|root,COG0845@2|Bacteria,2G6RK@200795|Chloroflexi,376DC@32061|Chloroflexia 32061|Chloroflexia MV TIGRFAM efflux transporter, RND family, MFP subunit - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 SJTD3_k127_2146184_2 546274.EIKCOROL_01664 2.759e-08 59.0 COG0477@1|root,COG2814@2|Bacteria,1MVQQ@1224|Proteobacteria,2VI4I@28216|Betaproteobacteria,2KPKM@206351|Neisseriales 206351|Neisseriales EGP Transporter, major facilitator family protein - - - ko:K08195,ko:K08369 - - - - ko00000,ko02000 2.A.1,2.A.1.15 - - MFS_1,MFS_4,Sugar_tr SJTD3_k127_2148333_0 1128421.JAGA01000002_gene1329 3.849e-44 182.0 COG0642@1|root,COG2203@1|root,COG3852@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3852@2|Bacteria,2NQNP@2323|unclassified Bacteria 2|Bacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - GAF,GAF_2,GGDEF,HATPase_c,HisKA,HisKA_7TM,PAS,PAS_3,PAS_4,PAS_9,Response_reg SJTD3_k127_2148333_1 1192034.CAP_8941 2.568e-30 130.0 COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions 1224|Proteobacteria T PFAM response regulator receiver - - - - - - - - - - - - Response_reg SJTD3_k127_2150069_0 1121378.KB899707_gene1405 2.051e-39 153.0 COG2259@1|root,COG2259@2|Bacteria,1WMJ4@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S DoxX - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxD,DoxX SJTD3_k127_2150069_1 555088.DealDRAFT_1906 3.482e-37 146.0 COG0517@1|root,COG0517@2|Bacteria,1V0XU@1239|Firmicutes,24I2P@186801|Clostridia,42JYZ@68298|Syntrophomonadaceae 186801|Clostridia S PFAM CBS domain containing protein acuB - - ko:K04767 - - - - ko00000 - - - ACT,CBS SJTD3_k127_2150069_2 42256.RradSPS_1860 4.05e-10 62.0 COG2320@1|root,COG2320@2|Bacteria,2GTS4@201174|Actinobacteria,4CQMS@84995|Rubrobacteria 84995|Rubrobacteria S GrpB protein - - - - - - - - - - - - GrpB SJTD3_k127_2151456_0 1122917.KB899686_gene3268 2.948e-294 910.0 COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,4HB1E@91061|Bacilli,26SW8@186822|Paenibacillaceae 91061|Bacilli G the aldose L-fucose into the corresponding ketose L-fuculose fucI - 5.3.1.25,5.3.1.3 ko:K01818 ko00051,ko01120,map00051,map01120 - R03163 RC00434 ko00000,ko00001,ko01000 - - - Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 SJTD3_k127_2158042_2 273068.TTE2131 2.138e-122 417.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,42EQG@68295|Thermoanaerobacterales 186801|Clostridia C PFAM NADH flavin oxidoreductase NADH oxidase - - - - - - - - - - - - Oxidored_FMN,Pyr_redox_2 SJTD3_k127_2158042_3 592015.HMPREF1705_01677 5.587e-120 403.0 COG1070@1|root,COG1070@2|Bacteria,3TBDX@508458|Synergistetes 508458|Synergistetes G FGGY family of carbohydrate kinases, N-terminal domain - - - - - - - - - - - - FGGY_C,FGGY_N SJTD3_k127_2158042_0 1267535.KB906767_gene3413 7.724e-161 518.0 COG1053@1|root,COG1053@2|Bacteria 2|Bacteria C succinate dehydrogenase cctA GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.3.5.4 ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 M00009,M00011,M00150,M00173 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Cytochrom_c3_2,FAD_binding_2,FAD_oxidored SJTD3_k127_2158042_1 357808.RoseRS_2516 1.438e-137 445.0 COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,377RE@32061|Chloroflexia 32061|Chloroflexia H PFAM Methionine synthase, vitamin-B12 independent - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 SJTD3_k127_2173395_3 709986.Deima_2442 1.709e-11 69.0 COG0477@1|root,COG2814@2|Bacteria,1WIWD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EGP PFAM Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_2173395_0 357808.RoseRS_2358 1.887e-61 236.0 COG1525@1|root,COG1572@1|root,COG1525@2|Bacteria,COG1572@2|Bacteria,2G86R@200795|Chloroflexi,3757A@32061|Chloroflexia 32061|Chloroflexia G PFAM peptidase domain protein - - - - - - - - - - - - NPCBM_assoc,PPC SJTD3_k127_2173395_2 313603.FB2170_03475 5.098e-22 112.0 COG3934@1|root,COG3934@2|Bacteria,4NHVX@976|Bacteroidetes,1HY3I@117743|Flavobacteriia,2PGN8@252356|Maribacter 976|Bacteroidetes G Cellulase (glycosyl hydrolase family 5) - - - - - - - - - - - - Cellulase,Glyco_hydro_2_C SJTD3_k127_2173395_1 479434.Sthe_2188 1.64e-26 116.0 COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase S1 and S6, chymotrypsin Hap - - 1.3.1.74 ko:K08070 - - - - ko00000,ko01000 - - - PDZ_2,Trypsin_2 SJTD3_k127_217431_2 1265313.HRUBRA_00753 1.858e-06 51.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1J559@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iJN746.PP_2469 Phe_tRNA-synt_N,tRNA-synt_2d SJTD3_k127_217431_0 767817.Desgi_3358 1.878e-16 80.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,262YN@186807|Peptococcaceae 186801|Clostridia KT Stress-responsive transcriptional regulator - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC SJTD3_k127_217431_1 1435356.Y013_09945 1.21e-08 64.0 COG1983@1|root,COG1983@2|Bacteria,2GWIA@201174|Actinobacteria 201174|Actinobacteria KT Phage shock protein C (PspC) - - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC SJTD3_k127_217431_3 871968.DESME_03645 3.674e-05 54.0 2DPQR@1|root,3330J@2|Bacteria,1VF83@1239|Firmicutes,25EKT@186801|Clostridia,2645C@186807|Peptococcaceae 186801|Clostridia - - - - - - - - - - - - - - - SJTD3_k127_217574_2 518766.Rmar_1384 1.281e-16 85.0 COG0346@1|root,COG0346@2|Bacteria,4NGE0@976|Bacteroidetes,1FJ8Q@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - ko:K15975 - - - - ko00000 - - - Glyoxalase SJTD3_k127_217574_4 1380355.JNIJ01000007_gene3212 0.0004845 45.0 COG0500@1|root,COG2226@2|Bacteria,1MXP4@1224|Proteobacteria,2TQU4@28211|Alphaproteobacteria,3JVXR@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SJTD3_k127_217574_0 1223523.H340_30583 3.136e-51 193.0 COG3485@1|root,COG3485@2|Bacteria,2GNNC@201174|Actinobacteria 201174|Actinobacteria Q catechol 1,2-dioxygenase - - - - - - - - - - - - Dioxygenase_C SJTD3_k127_217574_1 926569.ANT_26930 6.112e-28 116.0 COG0370@1|root,COG0370@2|Bacteria 2|Bacteria P ferrous iron transmembrane transporter activity feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate SJTD3_k127_2190179_0 479434.Sthe_1950 1.275e-87 310.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,2G5Q5@200795|Chloroflexi,27Y10@189775|Thermomicrobia 200795|Chloroflexi EU PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - - - - - - - - - - PD40,Peptidase_S9 SJTD3_k127_2190179_1 115417.EPrPW00000023836 1.122e-70 249.0 COG0458@1|root,KOG0370@2759|Eukaryota,1MADF@121069|Pythiales 121069|Pythiales EF Aspartate carbamoyltransferase. Source PGD - - - - - - - - - - - - OTCace,OTCace_N SJTD3_k127_2196269_1 794846.AJQU01000112_gene3556 2.128e-23 101.0 COG0596@1|root,COG0596@2|Bacteria,1MUVB@1224|Proteobacteria,2TREP@28211|Alphaproteobacteria,4BAJY@82115|Rhizobiaceae 28211|Alphaproteobacteria S Alpha beta hydrolase - - 3.8.1.3 ko:K01561 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - Abhydrolase_1 SJTD3_k127_2196269_0 1128421.JAGA01000003_gene3711 5.623e-247 774.0 COG0188@1|root,COG0188@2|Bacteria,2NNNR@2323|unclassified Bacteria 2|Bacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV SJTD3_k127_2197489_2 720554.Clocl_2858 2.239e-65 234.0 COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae 186801|Clostridia M Belongs to the peptidase S11 family dacB2 - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 SJTD3_k127_2197489_0 215803.DB30_1336 8.233e-84 289.0 COG4555@1|root,COG4555@2|Bacteria,1QU2T@1224|Proteobacteria,43BX9@68525|delta/epsilon subdivisions,2X782@28221|Deltaproteobacteria,2YUK4@29|Myxococcales 28221|Deltaproteobacteria CP ABC transporter natA - 3.6.3.7 ko:K09697 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.115 - - ABC_tran SJTD3_k127_2197489_3 391625.PPSIR1_22054 8.705e-38 161.0 COG1668@1|root,COG1668@2|Bacteria,1R3RG@1224|Proteobacteria,43B64@68525|delta/epsilon subdivisions,2X6JN@28221|Deltaproteobacteria,2YVQ4@29|Myxococcales 28221|Deltaproteobacteria CP sodium ABC transporter, permease - - - ko:K09696 ko02010,ko02020,map02010,map02020 M00253 - - ko00000,ko00001,ko00002,ko02000 3.A.1.115 - - ABC2_membrane_2,Abi SJTD3_k127_2197489_1 927677.ALVU02000004_gene4738 1.787e-78 280.0 COG3903@1|root,COG3903@2|Bacteria 2|Bacteria K ADP binding - - - - - - - - - - - - AAA_22,DUF4062,NB-ARC,TPR_12 SJTD3_k127_2206072_1 926550.CLDAP_38610 9.198e-67 232.0 COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi 200795|Chloroflexi P Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K02056,ko:K10441 ko02010,map02010 M00212,M00221 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_2206072_0 1304874.JAFY01000002_gene563 4.328e-139 450.0 COG1879@1|root,COG1879@2|Bacteria,3TBZ2@508458|Synergistetes 508458|Synergistetes G Periplasmic binding protein domain - - - - - - - - - - - - Peripla_BP_4 SJTD3_k127_2206072_2 251229.Chro_0545 1.212e-54 199.0 COG2084@1|root,COG2084@2|Bacteria,1G1GH@1117|Cyanobacteria,3VISP@52604|Pleurocapsales 1117|Cyanobacteria I PFAM NAD binding domain of 6-phosphogluconate dehydrogenase - - 1.1.1.31 ko:K00020 ko00280,ko01100,map00280,map01100 - R05066 RC00099 ko00000,ko00001,ko01000 - - - NAD_binding_11,NAD_binding_2 SJTD3_k127_2213643_0 1242864.D187_000948 1.764e-171 564.0 COG0308@1|root,COG0308@2|Bacteria,1MUCI@1224|Proteobacteria,42KZI@68525|delta/epsilon subdivisions,2WJ2C@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Peptidase M1 membrane alanine aminopeptidase pepN - 3.4.11.2 ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - DUF3458,DUF3458_C,ERAP1_C,Peptidase_M1 SJTD3_k127_2213643_2 1242864.D187_005544 1.795e-89 308.0 COG1819@1|root,COG1819@2|Bacteria,1PVC0@1224|Proteobacteria,434ZI@68525|delta/epsilon subdivisions,2WZAA@28221|Deltaproteobacteria,2Z1PJ@29|Myxococcales 28221|Deltaproteobacteria CG UDP-glucoronosyl and UDP-glucosyl transferase - - - - - - - - - - - - UDPGT SJTD3_k127_2213643_3 485913.Krac_9424 5.826e-64 227.0 COG0596@1|root,COG0596@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_2213643_4 1408473.JHXO01000015_gene1896 2.003e-05 53.0 2EGQV@1|root,33AH0@2|Bacteria,4P5D6@976|Bacteroidetes,2FYZA@200643|Bacteroidia 976|Bacteroidetes - - - - - - - - - - - - - - - SJTD3_k127_2213643_1 479434.Sthe_1293 3.979e-115 377.0 COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,27XJC@189775|Thermomicrobia 189775|Thermomicrobia F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 SJTD3_k127_2216230_8 1121422.AUMW01000017_gene1972 2.118e-13 73.0 COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,261KY@186807|Peptococcaceae 186801|Clostridia S Belongs to the multicopper oxidase YfiH RL5 family yfiH - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 SJTD3_k127_2216230_3 1382306.JNIM01000001_gene3786 5.506e-52 192.0 COG0325@1|root,COG0325@2|Bacteria,2G6F1@200795|Chloroflexi 200795|Chloroflexi S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis - - - ko:K06997 - - - - ko00000 - - - Ala_racemase_N SJTD3_k127_2216230_1 1382356.JQMP01000003_gene1463 3.062e-122 407.0 COG0617@1|root,COG0617@2|Bacteria,2G6B7@200795|Chloroflexi,27Y1Y@189775|Thermomicrobia 189775|Thermomicrobia J Probable RNA and SrmB- binding site of polymerase A - - 2.7.7.19 ko:K00970 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - HD,PolyA_pol,PolyA_pol_RNAbd SJTD3_k127_2216230_6 204669.Acid345_4635 1.269e-15 83.0 COG3918@1|root,COG3918@2|Bacteria,3Y5QM@57723|Acidobacteria,2JJXI@204432|Acidobacteriia 204432|Acidobacteriia S membrane - - - - - - - - - - - - DUF4126 SJTD3_k127_2216230_9 1123290.AUDQ01000022_gene745 2.838e-07 63.0 COG0791@1|root,COG0791@2|Bacteria,1V9FW@1239|Firmicutes,4HISN@91061|Bacilli,26FSP@186818|Planococcaceae 91061|Bacilli M S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_2216230_7 449447.MAE_21930 6.704e-15 88.0 2DU7S@1|root,33P96@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_2216230_2 1111069.TCCBUS3UF1_17270 2.112e-78 279.0 COG1572@1|root,COG1572@2|Bacteria,1WM7M@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Domain of unknown function (DUF5122) beta-propeller - - - - - - - - - - - - DUF5122 SJTD3_k127_2216230_4 266117.Rxyl_2442 1.013e-28 121.0 COG1547@1|root,COG1547@2|Bacteria 2|Bacteria S Domain of unknown function (DUF309) ypuF - - ko:K09763 - - - - ko00000 - - - DUF309 SJTD3_k127_2216230_0 1267535.KB906767_gene210 3.472e-125 417.0 COG3004@1|root,COG3004@2|Bacteria 2|Bacteria P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons nhaA - - ko:K03313 - - - - ko00000,ko02000 2.A.33.1 - - Na_H_antiport_1 SJTD3_k127_2216230_5 370438.PTH_2384 1.123e-26 117.0 COG1595@1|root,COG1595@2|Bacteria,1V4E2@1239|Firmicutes,24GZP@186801|Clostridia,262C3@186807|Peptococcaceae 186801|Clostridia K TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 SJTD3_k127_2217961_3 1078085.HMPREF1210_01586 1.734e-05 59.0 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HEC8@91061|Bacilli,26I8Q@186818|Planococcaceae 91061|Bacilli M Cell wall-associated - - - - - - - - - - - - NLPC_P60,SLH SJTD3_k127_2217961_1 525904.Tter_2777 6.757e-24 120.0 COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria 2|Bacteria G Galactose oxidase, central domain - - - - - - - - - - - - Big_5,CBM_35,CBM_6,GSDH,Kelch_1,Kelch_6 SJTD3_k127_2217961_2 1124780.ANNU01000038_gene185 3.811e-21 111.0 COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NG09@976|Bacteroidetes,47NP4@768503|Cytophagia 976|Bacteroidetes S Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,PKD,Peptidase_M36 SJTD3_k127_2217961_0 926560.KE387023_gene2500 1.117e-146 510.0 COG3055@1|root,COG3055@2|Bacteria 2|Bacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - Kelch_1,Malectin,TIG SJTD3_k127_2218952_4 316274.Haur_4220 5.743e-68 237.0 COG1403@1|root,COG1403@2|Bacteria,2G6WV@200795|Chloroflexi,375TQ@32061|Chloroflexia 32061|Chloroflexia L SMART HNH nuclease - - - - - - - - - - - - HNH_5 SJTD3_k127_2218952_0 420246.GTNG_0013 1.162e-163 530.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli,1WFR9@129337|Geobacillus 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b SJTD3_k127_2218952_2 309801.trd_1939 5.704e-85 307.0 COG0739@1|root,COG1388@1|root,COG0739@2|Bacteria,COG1388@2|Bacteria,2G6Q7@200795|Chloroflexi,27XYA@189775|Thermomicrobia 189775|Thermomicrobia M SMART Peptidoglycan-binding LysM - - - - - - - - - - - - LysM,Peptidase_M23 SJTD3_k127_2218952_5 383372.Rcas_1378 1.252e-59 221.0 COG1912@1|root,COG1912@2|Bacteria,2G6NI@200795|Chloroflexi,376J1@32061|Chloroflexia 32061|Chloroflexia S S-adenosyl-l-methionine hydroxide adenosyltransferase - - - ko:K22205 - - - - ko00000,ko01000 - - - SAM_adeno_trans SJTD3_k127_2218952_7 1128421.JAGA01000004_gene2520 3.198e-36 149.0 COG1354@1|root,COG1354@2|Bacteria,2NPM8@2323|unclassified Bacteria 2|Bacteria D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA SJTD3_k127_2218952_9 357808.RoseRS_0193 6.783e-15 81.0 COG1418@1|root,COG1418@2|Bacteria,2G7CI@200795|Chloroflexi,375YJ@32061|Chloroflexia 32061|Chloroflexia S mRNA catabolic process - - - - - - - - - - - - - SJTD3_k127_2218952_6 479434.Sthe_0390 5.295e-55 202.0 COG1994@1|root,COG1994@2|Bacteria,2G6VM@200795|Chloroflexi,27Y97@189775|Thermomicrobia 189775|Thermomicrobia S Peptidase M50 - - - - - - - - - - - - - SJTD3_k127_2218952_3 525904.Tter_0018 2.677e-73 259.0 COG1940@1|root,COG1940@2|Bacteria,2NPRP@2323|unclassified Bacteria 2|Bacteria GK ROK family glcK - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS10220 ROK SJTD3_k127_2218952_1 1382356.JQMP01000004_gene670 4.767e-96 323.0 COG1215@1|root,COG1215@2|Bacteria,2G6BS@200795|Chloroflexi,27Y06@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_2218952_8 324602.Caur_3622 2.534e-32 134.0 COG2520@1|root,COG2520@2|Bacteria 2|Bacteria J tRNA (guanine(37)-N(1))-methyltransferase activity XK27_03530 - - - - - - - - - - - Methyltransf_21,rRNA_methylase SJTD3_k127_2249094_4 866895.HBHAL_1682 9.672e-30 130.0 2DBMF@1|root,2Z9YG@2|Bacteria,1VYCA@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - SJTD3_k127_2249094_0 1174528.JH992898_gene3587 6.855e-193 607.0 COG2267@1|root,COG2267@2|Bacteria,1G75F@1117|Cyanobacteria 1117|Cyanobacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_2249094_1 1123269.NX02_01115 1.901e-116 390.0 COG0277@1|root,COG0277@2|Bacteria 2|Bacteria C FAD linked oxidase domain protein - - - - - - - - - - - - FAD_binding_4 SJTD3_k127_2249094_3 1189612.A33Q_1400 2.522e-34 140.0 COG0662@1|root,COG0662@2|Bacteria,4PMR4@976|Bacteroidetes 976|Bacteroidetes G Cupin domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_2249094_5 570268.ANBB01000035_gene2324 6.087e-26 113.0 COG0748@1|root,COG0748@2|Bacteria,2IIRE@201174|Actinobacteria,4EPSQ@85012|Streptosporangiales 201174|Actinobacteria P F420H(2)-dependent quinone reductase ddn GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 - - - - - - - - - - F420H2_quin_red SJTD3_k127_2249094_2 28072.Nos7524_1682 9.751e-80 268.0 COG2303@1|root,COG2303@2|Bacteria,1G5DG@1117|Cyanobacteria,1HRGW@1161|Nostocales 1117|Cyanobacteria E GMC oxidoreductase - - 1.1.3.6 ko:K03333 ko00984,ko01120,map00984,map01120 - R01459 RC00146 ko00000,ko00001,ko01000 - - - GMC_oxred_C,GMC_oxred_N SJTD3_k127_2249495_2 1078085.HMPREF1210_01586 6.457e-09 64.0 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HEC8@91061|Bacilli,26I8Q@186818|Planococcaceae 91061|Bacilli M Cell wall-associated - - - - - - - - - - - - NLPC_P60,SLH SJTD3_k127_2249495_0 378806.STAUR_7017 1.234e-105 372.0 COG2866@1|root,COG2866@2|Bacteria,1PFUZ@1224|Proteobacteria,43AHH@68525|delta/epsilon subdivisions,2X5XP@28221|Deltaproteobacteria,2YYQC@29|Myxococcales 28221|Deltaproteobacteria E Zn_pept - - - - - - - - - - - - Peptidase_M14 SJTD3_k127_2249495_1 1279009.ADICEAN_03023 1.508e-16 94.0 COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NG09@976|Bacteroidetes,47NP4@768503|Cytophagia 976|Bacteroidetes S Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,PKD,Peptidase_M36 SJTD3_k127_2254397_0 861299.J421_0893 2.314e-60 212.0 COG0780@1|root,COG0780@2|Bacteria,1ZTKZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes H Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF SJTD3_k127_2254397_1 1121121.KB894333_gene4598 1.247e-05 53.0 2ED1A@1|root,336Y8@2|Bacteria,1VNP3@1239|Firmicutes,4HRCX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - SJTD3_k127_226421_1 1128421.JAGA01000002_gene1186 8.832e-49 187.0 COG2339@1|root,COG2339@2|Bacteria 2|Bacteria D peptidase activity - - - - - - - - - - - - PrsW-protease SJTD3_k127_226421_0 797209.ZOD2009_19858 2.863e-84 290.0 COG0596@1|root,arCOG01648@2157|Archaea,2XSWV@28890|Euryarchaeota,23T2R@183963|Halobacteria 183963|Halobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) yfhM - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_226421_2 1203190.CAJP01000028_gene118 4.313e-05 48.0 COG1451@1|root,COG1451@2|Bacteria,2GMP6@201174|Actinobacteria,22N63@1653|Corynebacteriaceae 201174|Actinobacteria S Metal-dependent hydrolase - - - ko:K07043 - - - - ko00000 - - - DUF45 SJTD3_k127_2264915_0 1041826.FCOL_13330 4.352e-65 230.0 COG0469@1|root,COG0469@2|Bacteria,4NEEU@976|Bacteroidetes,1HX84@117743|Flavobacteriia,2NTJV@237|Flavobacterium 976|Bacteroidetes G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PK,PK_C SJTD3_k127_2264915_1 1521187.JPIM01000063_gene2484 4.064e-32 144.0 COG0823@1|root,COG3693@1|root,COG0823@2|Bacteria,COG3693@2|Bacteria,2GA75@200795|Chloroflexi,37735@32061|Chloroflexia 32061|Chloroflexia U nuclease - - - - - - - - - - - - - SJTD3_k127_2264915_2 1134413.ANNK01000016_gene1874 2.317e-20 106.0 COG1404@1|root,COG3103@1|root,COG1404@2|Bacteria,COG3103@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1ZPV5@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family - - - ko:K13277 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - A2M_N,CW_binding_2,Peptidase_S8,SLH SJTD3_k127_2264915_3 65497.JODV01000008_gene313 1.957e-10 74.0 COG0392@1|root,COG0392@2|Bacteria,2IC25@201174|Actinobacteria,4E1XV@85010|Pseudonocardiales 201174|Actinobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - Glycos_transf_2,LPG_synthase_TM SJTD3_k127_2265546_1 1382306.JNIM01000001_gene428 2.133e-19 92.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_2265546_2 357808.RoseRS_2190 5.209e-14 87.0 COG2373@1|root,COG2373@2|Bacteria,2G5XN@200795|Chloroflexi 200795|Chloroflexi S PFAM alpha-2-macroglobulin domain protein - - - ko:K06894 - - - - ko00000 - - - A2M,A2M_N,A2M_N_2,Big_5,MG1 SJTD3_k127_2265546_0 1521187.JPIM01000006_gene1768 7.632e-102 340.0 COG0766@1|root,COG0766@2|Bacteria,2G666@200795|Chloroflexi,374XF@32061|Chloroflexia 32061|Chloroflexia M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase SJTD3_k127_2267867_0 1305836.AXVE01000011_gene1124 4.958e-36 147.0 COG0454@1|root,COG0456@2|Bacteria,1UHRF@1239|Firmicutes,4IS7A@91061|Bacilli,26FN8@186818|Planococcaceae 91061|Bacilli K GNAT acetyltransferase - - - - - - - - - - - - GNAT_acetyltran SJTD3_k127_2285571_0 926692.AZYG01000064_gene1000 4.403e-93 318.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,248G0@186801|Clostridia,3WACN@53433|Halanaerobiales 186801|Clostridia S Required for morphogenesis under gluconeogenic growth conditions - - - - - - - - - - - - UPF0052 SJTD3_k127_2285571_2 293826.Amet_2893 4.101e-10 72.0 28SRE@1|root,2ZF1B@2|Bacteria,1W33E@1239|Firmicutes,24W3Z@186801|Clostridia,36PKN@31979|Clostridiaceae 186801|Clostridia - - - - - - - - - - - - - - CbiX,Ferrochelatase SJTD3_k127_2285571_1 1128421.JAGA01000002_gene589 1.533e-14 76.0 COG0008@1|root,COG0008@2|Bacteria,2NNMZ@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17,6.1.1.24 ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c SJTD3_k127_2292844_3 324602.Caur_1941 1.081e-50 183.0 COG0104@1|root,COG0104@2|Bacteria,2G602@200795|Chloroflexi,374RV@32061|Chloroflexia 32061|Chloroflexia F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA - 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt SJTD3_k127_2292844_0 1210884.HG799462_gene8911 1.354e-213 682.0 COG1061@1|root,COG1061@2|Bacteria,2IYCX@203682|Planctomycetes 203682|Planctomycetes L Helicase conserved C-terminal domain - - 3.6.4.12 ko:K10843 ko03022,ko03420,map03022,map03420 M00290 - - ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - ERCC3_RAD25_C,Helicase_C_3,ResIII SJTD3_k127_2292844_1 1382306.JNIM01000001_gene977 5.785e-53 208.0 COG0477@1|root,COG2814@2|Bacteria 1382306.JNIM01000001_gene977|- EGP Major facilitator Superfamily - - - - - - - - - - - - - SJTD3_k127_2292844_2 479434.Sthe_2298 4.207e-51 186.0 COG2096@1|root,COG2096@2|Bacteria,2G6TB@200795|Chloroflexi,27Y88@189775|Thermomicrobia 189775|Thermomicrobia S Cobalamin adenosyltransferase - - 2.5.1.17 ko:K00798 ko00860,ko01100,map00860,map01100 M00122 R01492,R05220,R07268 RC00533 ko00000,ko00001,ko00002,ko01000 - - - Cob_adeno_trans SJTD3_k127_2292844_4 479434.Sthe_2373 2.872e-17 89.0 COG5542@1|root,COG5542@2|Bacteria,2G72S@200795|Chloroflexi 200795|Chloroflexi S integral membrane protein - - - - - - - - - - - - Mannosyl_trans2 SJTD3_k127_2293388_0 1128421.JAGA01000002_gene866 2.354e-174 552.0 COG1063@1|root,COG1063@2|Bacteria 2|Bacteria E alcohol dehydrogenase MA20_31690 - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N SJTD3_k127_2293388_1 1382356.JQMP01000004_gene653 6.713e-51 188.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_2319905_3 316274.Haur_0504 7.573e-21 98.0 COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi,3775M@32061|Chloroflexia 32061|Chloroflexia S Belongs to the UPF0312 family - - - - - - - - - - - - YceI SJTD3_k127_2319905_4 443144.GM21_1895 4.017e-20 103.0 COG3485@1|root,COG3485@2|Bacteria 2|Bacteria Q protocatechuate 3,4-dioxygenase activity catA - 1.13.11.1 ko:K03381 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R00817,R04258,R05299,R08114,R08115,R09134 RC00388,RC00535,RC01366 ko00000,ko00001,ko00002,ko01000 - - - Dioxygenase_C SJTD3_k127_2319905_2 309801.trd_1960 5.603e-24 115.0 COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia 189775|Thermomicrobia M L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD SJTD3_k127_2319905_5 263358.VAB18032_24245 2.419e-08 66.0 2E1T4@1|root,32X2Z@2|Bacteria,2H4V9@201174|Actinobacteria,4DE78@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_2319905_1 316274.Haur_1591 1.518e-50 185.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_2319905_0 316274.Haur_1012 3.096e-83 288.0 COG0454@1|root,COG1246@1|root,COG0456@2|Bacteria,COG1246@2|Bacteria,2G8UQ@200795|Chloroflexi 200795|Chloroflexi K PFAM GCN5-related N-acetyltransferase - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_2328482_0 1124780.ANNU01000059_gene867 6.385e-160 510.0 COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,47KIY@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.41,3.2.1.68 ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 SJTD3_k127_2328482_1 247490.KSU1_C1307 3.706e-60 215.0 COG3280@1|root,COG3280@2|Bacteria,2IYFT@203682|Planctomycetes 203682|Planctomycetes G Alpha amylase, catalytic domain - - 5.4.99.15 ko:K06044 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R01824,R09995 - ko00000,ko00001,ko00002,ko01000 - GH13 - Alpha-amylase SJTD3_k127_2344326_3 931627.MycrhDRAFT_1510 7.878e-07 62.0 COG4447@1|root,COG4447@2|Bacteria,2GPVZ@201174|Actinobacteria,23B1S@1762|Mycobacteriaceae 201174|Actinobacteria S cellulose binding - - - - - - - - - - - - - SJTD3_k127_2344326_1 1463825.JNXC01000017_gene6974 9.883e-79 283.0 COG1633@1|root,COG1633@2|Bacteria 2|Bacteria S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - AurF,Fer4_19,Ferritin-like,zf-CDGSH SJTD3_k127_2344326_0 497964.CfE428DRAFT_0631 6.723e-134 463.0 COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,46TZ3@74201|Verrucomicrobia 74201|Verrucomicrobia T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,NB-ARC SJTD3_k127_2344326_2 1298863.AUEP01000005_gene2633 2.081e-27 111.0 COG2114@1|root,COG2114@2|Bacteria,2I1DZ@201174|Actinobacteria,4DVRA@85009|Propionibacteriales 201174|Actinobacteria T Protein of unknown function (DUF4242) - - - - - - - - - - - - DUF4242 SJTD3_k127_234729_1 926550.CLDAP_12050 2.301e-62 222.0 COG0584@1|root,COG0584@2|Bacteria 2|Bacteria C glycerophosphodiester phosphodiesterase activity glpQ2 - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD SJTD3_k127_234729_0 485913.Krac_3330 2.157e-78 271.0 COG1708@1|root,COG1708@2|Bacteria,2G7IZ@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4111) - - 2.7.7.47 ko:K00984 - - - - ko00000,ko01000,ko01504 - - - DUF4111,NTP_transf_2 SJTD3_k127_234729_2 936136.ARRT01000007_gene1324 9.649e-61 212.0 COG3119@1|root,COG3119@2|Bacteria,1MWY7@1224|Proteobacteria,2TV04@28211|Alphaproteobacteria,4B8BM@82115|Rhizobiaceae 28211|Alphaproteobacteria P Sulfatase - - - - - - - - - - - - Sulfatase SJTD3_k127_2353980_3 1121930.AQXG01000009_gene335 6.352e-14 76.0 COG0110@1|root,COG0110@2|Bacteria,4PIST@976|Bacteroidetes,1IUN2@117747|Sphingobacteriia 976|Bacteroidetes S PFAM Bacterial transferase hexapeptide (three repeats) - - - - - - - - - - - - Hexapep_2 SJTD3_k127_2353980_0 479434.Sthe_0245 6.734e-87 302.0 COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi,27XSJ@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4 SJTD3_k127_2353980_2 485913.Krac_8068 4.33e-40 166.0 COG0110@1|root,COG0110@2|Bacteria,2G6D2@200795|Chloroflexi 200795|Chloroflexi S PFAM transferase hexapeptide repeat containing protein - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep SJTD3_k127_2353980_1 1382306.JNIM01000001_gene2996 2.145e-59 215.0 COG2244@1|root,COG2244@2|Bacteria,2G6CM@200795|Chloroflexi 200795|Chloroflexi S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C SJTD3_k127_2354484_1 1210884.HG799463_gene9897 8.85e-31 136.0 COG0500@1|root,COG2226@2|Bacteria,2J51A@203682|Planctomycetes 203682|Planctomycetes Q Methionine biosynthesis protein MetW - - - - - - - - - - - - Methyltransf_23 SJTD3_k127_2354484_0 485913.Krac_10537 5.25e-104 344.0 COG0274@1|root,COG0274@2|Bacteria,2G7HC@200795|Chloroflexi 200795|Chloroflexi H Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC - 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - - DeoC SJTD3_k127_2360693_2 765420.OSCT_3178 1.903e-42 159.0 COG0318@1|root,COG0318@2|Bacteria,2G5K4@200795|Chloroflexi,3758A@32061|Chloroflexia 32061|Chloroflexia IQ PFAM AMP-dependent synthetase and ligase - - - ko:K00666 - - - - ko00000,ko01000,ko01004 - - - AMP-binding,AMP-binding_C SJTD3_k127_2360693_1 1128421.JAGA01000001_gene2269 1.869e-101 340.0 COG1028@1|root,COG1028@2|Bacteria,2NQB4@2323|unclassified Bacteria 2|Bacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SJTD3_k127_2360693_0 1128421.JAGA01000001_gene2270 7.013e-133 427.0 COG0332@1|root,COG0332@2|Bacteria,2NQSU@2323|unclassified Bacteria 2|Bacteria I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C SJTD3_k127_2364599_2 926560.KE387026_gene4277 1.42e-70 248.0 COG0395@1|root,COG0395@2|Bacteria 2|Bacteria P glycerophosphodiester transmembrane transport - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SJTD3_k127_2364599_0 357808.RoseRS_3149 9.963e-133 439.0 COG1653@1|root,COG1653@2|Bacteria,2G82H@200795|Chloroflexi,377G1@32061|Chloroflexia 32061|Chloroflexia G PFAM extracellular solute-binding protein family 1 - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_8 SJTD3_k127_2364599_4 525904.Tter_1618 7.322e-13 73.0 2CAGF@1|root,2ZVUU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_2364599_3 479434.Sthe_2012 4.208e-38 153.0 COG0850@1|root,COG0850@2|Bacteria,2G6VN@200795|Chloroflexi,27YGI@189775|Thermomicrobia 189775|Thermomicrobia D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization minC - - ko:K03610 - - - - ko00000,ko03036,ko04812 - - - MinC_C SJTD3_k127_2364599_1 309801.trd_1927 1.885e-117 393.0 COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi,27Y4X@189775|Thermomicrobia 189775|Thermomicrobia M Penicillin-binding Protein dimerisation domain - - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase SJTD3_k127_2368478_4 35754.JNYJ01000003_gene6468 2.122e-10 66.0 2ES3U@1|root,33JNT@2|Bacteria,2GPSP@201174|Actinobacteria,4DJRZ@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_2368478_3 717606.PaecuDRAFT_1467 6.365e-13 74.0 COG0477@1|root,COG0477@2|Bacteria,1UXX6@1239|Firmicutes,4HF8Y@91061|Bacilli,26TS2@186822|Paenibacillaceae 91061|Bacilli EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_2368478_6 1121272.KB903255_gene5680 5.851e-10 74.0 COG1404@1|root,COG1404@2|Bacteria,2I61R@201174|Actinobacteria,4DBU1@85008|Micromonosporales 201174|Actinobacteria GO Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CarboxypepD_reg,Peptidase_S8 SJTD3_k127_2368478_1 1183438.GKIL_2106 1.087e-64 253.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - CBM_2 SJTD3_k127_2368478_2 35754.JNYJ01000047_gene3594 6.613e-14 87.0 COG3209@1|root,COG3209@2|Bacteria,2GK1D@201174|Actinobacteria,4DBZ4@85008|Micromonosporales 201174|Actinobacteria M RHS Repeat - - - - - - - - - - - - PT-HINT,RHS_repeat,SpvB SJTD3_k127_2368478_5 1243664.CAVL020000028_gene115 2.561e-10 75.0 COG3103@1|root,COG5492@1|root,COG3103@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - 3D,Big_2,Big_3_2,CBM_X2,SH3_3,SLH SJTD3_k127_2368478_0 635013.TherJR_2325 9.105e-79 271.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,260WY@186807|Peptococcaceae 186801|Clostridia G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C SJTD3_k127_2372262_0 1121377.KB906410_gene623 1.024e-72 250.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase ybaJ - - - - - - - - - - - Methyltransf_11 SJTD3_k127_2372262_1 765913.ThidrDRAFT_0627 2.587e-72 252.0 COG0500@1|root,COG2226@2|Bacteria,1N3VV@1224|Proteobacteria,1SCTZ@1236|Gammaproteobacteria,1WZXH@135613|Chromatiales 135613|Chromatiales Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - - - - - - - - - - - SJTD3_k127_2373172_0 384765.SIAM614_08529 1.85e-71 248.0 COG3221@1|root,COG3221@2|Bacteria,1MWFF@1224|Proteobacteria,2TUB4@28211|Alphaproteobacteria 28211|Alphaproteobacteria P COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - ko:K02044 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - Phosphonate-bd SJTD3_k127_2384973_5 1122164.JHWF01000022_gene1733 2.032e-05 48.0 2BNP9@1|root,32HCB@2|Bacteria,1QBYA@1224|Proteobacteria,1T7JI@1236|Gammaproteobacteria,1JFGD@118969|Legionellales 118969|Legionellales - - - - - - - - - - - - - - - SJTD3_k127_2384973_4 1463900.JOIX01000073_gene5505 1.11e-05 56.0 COG3415@1|root,COG3415@2|Bacteria,2HK0D@201174|Actinobacteria 201174|Actinobacteria L Transposase - - - - - - - - - - - - HTH_23,Terminase_5 SJTD3_k127_2384973_1 1128421.JAGA01000002_gene690 3.81e-66 228.0 COG0048@1|root,COG0048@2|Bacteria,2NPA7@2323|unclassified Bacteria 2|Bacteria J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 SJTD3_k127_2384973_2 479434.Sthe_1032 3.215e-64 223.0 COG0049@1|root,COG0049@2|Bacteria,2G6GR@200795|Chloroflexi,27Y66@189775|Thermomicrobia 189775|Thermomicrobia J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG - - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 SJTD3_k127_2384973_0 525904.Tter_0712 1.308e-270 843.0 COG0480@1|root,COG0480@2|Bacteria,2NNSV@2323|unclassified Bacteria 2|Bacteria J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 SJTD3_k127_2387532_1 479434.Sthe_2110 9.626e-43 171.0 COG2373@1|root,COG2373@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia 189775|Thermomicrobia P alginic acid biosynthetic process - - - - - - - - - - - - - SJTD3_k127_2387532_0 865861.AZSU01000003_gene2104 2.541e-99 336.0 COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia,36DKU@31979|Clostridiaceae 186801|Clostridia Q Psort location Cytoplasmic, score 7.50 - - - - - - - - - - - - Amidohydro_1 SJTD3_k127_2397967_0 644966.Tmar_0325 4.52e-91 308.0 COG1290@1|root,COG1290@2|Bacteria,1TP6M@1239|Firmicutes,24K8U@186801|Clostridia 186801|Clostridia C Cytochrome b subunit of the bc - - - ko:K00412,ko:K02635 ko00190,ko00195,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map00195,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152,M00162 - - ko00000,ko00001,ko00002,ko00194,ko03029 - - - Cytochrome_B SJTD3_k127_2397967_2 928724.SacglDRAFT_00681 3.32e-35 148.0 COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,4DXDI@85010|Pseudonocardiales 201174|Actinobacteria M PFAM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_2397967_1 1128421.JAGA01000003_gene3596 4.935e-62 220.0 COG0745@1|root,COG0745@2|Bacteria,2NR2D@2323|unclassified Bacteria 2|Bacteria T Transcriptional regulatory protein, C terminal - - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SJTD3_k127_2397967_3 525904.Tter_1495 2.141e-26 112.0 COG0642@1|root,COG2205@2|Bacteria,2NQZ3@2323|unclassified Bacteria 2|Bacteria T Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - - - - - - - - - - HATPase_c,HisKA SJTD3_k127_2418465_0 356851.JOAN01000032_gene2763 1.274e-115 392.0 COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4D90U@85008|Micromonosporales 201174|Actinobacteria E Peptidase M1 membrane alanine aminopeptidase - - - - - - - - - - - - Peptidase_M1 SJTD3_k127_2418465_3 485913.Krac_5452 5.51e-31 126.0 2CWCM@1|root,32SZF@2|Bacteria,2G973@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4260) - - - - - - - - - - - - DUF4260 SJTD3_k127_2418465_1 1487953.JMKF01000004_gene672 3.925e-50 183.0 COG2219@1|root,COG2219@2|Bacteria,1G7G7@1117|Cyanobacteria 1117|Cyanobacteria L DNA primase activity - - - - - - - - - - - - - SJTD3_k127_2418465_2 1114959.SZMC14600_18194 9.196e-39 160.0 COG1287@1|root,COG1287@2|Bacteria,2GMZM@201174|Actinobacteria,4E0ZH@85010|Pseudonocardiales 201174|Actinobacteria S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_2420566_2 357808.RoseRS_1781 1.042e-58 214.0 COG1716@1|root,COG1716@2|Bacteria,2G79K@200795|Chloroflexi,37509@32061|Chloroflexia 32061|Chloroflexia T PFAM Forkhead-associated protein - - - - - - - - - - - - DUF3662,FHA SJTD3_k127_2420566_7 1128421.JAGA01000002_gene1898 1.274e-28 124.0 COG1716@1|root,COG1716@2|Bacteria,2NRHK@2323|unclassified Bacteria 2|Bacteria T Inner membrane component of T3SS, cytoplasmic domain - - - - - - - - - - - - FHA,Yop-YscD_cpl SJTD3_k127_2420566_1 316274.Haur_2665 3.179e-90 328.0 COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi,375CP@32061|Chloroflexia 32061|Chloroflexia V PFAM VanW family protein - - - - - - - - - - - - PG_binding_4,VanW SJTD3_k127_2420566_8 1303518.CCALI_02109 1.392e-13 83.0 COG1413@1|root,COG1413@2|Bacteria 2|Bacteria C deoxyhypusine monooxygenase activity - - - - - - - - - - - - HEAT_2,HEAT_PBS SJTD3_k127_2420566_3 525904.Tter_0213 4.71e-57 206.0 COG3247@1|root,COG3247@2|Bacteria 2|Bacteria U response to pH - - - - - - - - - - - - DUF308 SJTD3_k127_2420566_4 1379698.RBG1_1C00001G1071 1.691e-54 196.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB_2 SJTD3_k127_2420566_9 357808.RoseRS_1951 2.718e-05 57.0 COG0457@1|root,COG0457@2|Bacteria,2G9Z0@200795|Chloroflexi,377FD@32061|Chloroflexia 32061|Chloroflexia NU Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - - SJTD3_k127_2420566_5 1449350.OCH239_16205 1.853e-32 143.0 COG1594@1|root,COG1594@2|Bacteria,1MWK8@1224|Proteobacteria,2U0YM@28211|Alphaproteobacteria,4KM5N@93682|Roseivivax 28211|Alphaproteobacteria K COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase - - - - - - - - - - - - zf-RRN7 SJTD3_k127_2420566_6 1122221.JHVI01000038_gene2116 3.228e-32 138.0 COG3603@1|root,COG3603@2|Bacteria,1WN1I@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S COGs COG3603 conserved - - - ko:K09707 - - - - ko00000 - - - ACT_7 SJTD3_k127_2420566_0 986075.CathTA2_2561 3.873e-158 508.0 COG0156@1|root,COG0156@2|Bacteria,1TPUX@1239|Firmicutes,4HAH3@91061|Bacilli 91061|Bacilli E Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide kbl GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 ko:K00639 ko00260,map00260 - R00371 RC00004,RC00394 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 SJTD3_k127_2430659_1 485913.Krac_2128 2.889e-151 482.0 COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi 200795|Chloroflexi H AMP-binding enzyme - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 SJTD3_k127_2430659_5 1500257.JQNM01000001_gene3429 5.775e-20 104.0 2CXTU@1|root,32T2K@2|Bacteria,1N5AY@1224|Proteobacteria,2UDIB@28211|Alphaproteobacteria,4BEAP@82115|Rhizobiaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - DUF1176 SJTD3_k127_2430659_6 357808.RoseRS_0664 1.321e-18 100.0 COG1404@1|root,COG1404@2|Bacteria,2G7HM@200795|Chloroflexi,375CA@32061|Chloroflexia 32061|Chloroflexia M PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - Peptidase_S8 SJTD3_k127_2430659_0 485913.Krac_2131 6.031e-179 567.0 COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi 200795|Chloroflexi C PFAM acyl-CoA dehydrogenase domain protein - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SJTD3_k127_2430659_7 485913.Krac_2132 1.227e-12 68.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process abmE - - - - - - - - - - - Ribonuc_L-PSP SJTD3_k127_2430659_4 485913.Krac_2132 8.639e-21 101.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process abmE - - - - - - - - - - - Ribonuc_L-PSP SJTD3_k127_2430659_3 357808.RoseRS_4070 5.333e-24 111.0 COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi,3753A@32061|Chloroflexia 32061|Chloroflexia O ATPase associated with various cellular activities, AAA_5 - - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N SJTD3_k127_2430659_2 485913.Krac_2147 7.501e-41 153.0 COG1024@1|root,COG1024@2|Bacteria,2G6G6@200795|Chloroflexi 2|Bacteria I PFAM Enoyl-CoA hydratase isomerase MA20_38145 - - - - - - - - - - - ECH_1 SJTD3_k127_2430989_1 58123.JOFJ01000008_gene492 1.647e-13 76.0 COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria,4EKJ9@85012|Streptosporangiales 201174|Actinobacteria M Glycosyl transferase 4-like domain - - - ko:K19424 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_2430989_0 1381123.AYOD01000008_gene3150 8.205e-90 314.0 COG0125@1|root,COG0125@2|Bacteria,1RA0K@1224|Proteobacteria,2VGKS@28211|Alphaproteobacteria 28211|Alphaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - - - - - - - - - - - SJTD3_k127_2433290_2 552811.Dehly_1126 6.598e-24 106.0 COG0637@1|root,COG1214@1|root,COG0637@2|Bacteria,COG1214@2|Bacteria,2G6ZZ@200795|Chloroflexi,34D2B@301297|Dehalococcoidia 301297|Dehalococcoidia O Glycoprotease family - - - - - - - - - - - - HAD_2,Peptidase_M22 SJTD3_k127_2433290_0 326427.Cagg_1904 4.746e-49 186.0 COG0500@1|root,COG2226@2|Bacteria,2G6N8@200795|Chloroflexi,375GC@32061|Chloroflexia 32061|Chloroflexia Q Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_25 SJTD3_k127_2433290_1 485913.Krac_8460 7.51e-40 160.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 SJTD3_k127_2433290_3 1382304.JNIL01000001_gene503 1.379e-13 79.0 arCOG07989@1|root,2ZFRA@2|Bacteria,1W6SP@1239|Firmicutes,4HZQI@91061|Bacilli 91061|Bacilli S COG1592 Rubrerythrin - - - - - - - - - - - - - SJTD3_k127_2451342_2 485913.Krac_11844 2.847e-11 69.0 COG0477@1|root,COG0477@2|Bacteria,2G5J9@200795|Chloroflexi 200795|Chloroflexi P TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_2451342_1 192952.MM_3157 7.753e-109 372.0 COG1680@1|root,arCOG00771@2157|Archaea 2157|Archaea V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - iAF692.Mbar_A1202 Beta-lactamase SJTD3_k127_2451342_0 192952.MM_3157 1.344e-111 381.0 COG1680@1|root,arCOG00771@2157|Archaea 2157|Archaea V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - iAF692.Mbar_A1202 Beta-lactamase SJTD3_k127_245289_2 292459.STH1622 0.0002214 49.0 COG0457@1|root,COG3359@1|root,COG0457@2|Bacteria,COG3359@2|Bacteria,1TQQU@1239|Firmicutes 1239|Firmicutes L Exonuclease yprB - - ko:K07502 - - - - ko00000 - - - RNase_H_2 SJTD3_k127_245289_1 1144275.COCOR_05928 1.065e-42 181.0 COG4447@1|root,COG4447@2|Bacteria,1PK4F@1224|Proteobacteria,437G7@68525|delta/epsilon subdivisions,2XA3A@28221|Deltaproteobacteria,2YVKV@29|Myxococcales 28221|Deltaproteobacteria S cellulose binding - - - - - - - - - - - - - SJTD3_k127_245289_0 945713.IALB_0216 1.063e-66 259.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - - SJTD3_k127_2458208_7 743525.TSC_c11640 8.658e-22 108.0 COG1917@1|root,COG1917@2|Bacteria,1WMI0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Cupin domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_2458208_3 67332.FM21_18600 6.055e-54 196.0 COG2085@1|root,COG2085@2|Bacteria,2I8W4@201174|Actinobacteria 201174|Actinobacteria S PFAM NADP oxidoreductase coenzyme F420-dependent - - 1.5.1.40 ko:K06988 - - - - ko00000,ko01000 - - - F420_oxidored SJTD3_k127_2458208_6 1121405.dsmv_3288 8.051e-26 109.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,42UQP@68525|delta/epsilon subdivisions,2WQKU@28221|Deltaproteobacteria,2MMAC@213118|Desulfobacterales 28221|Deltaproteobacteria S RNA recognition motif - - - - - - - - - - - - RRM_1 SJTD3_k127_2458208_2 649638.Trad_1784 3.051e-65 231.0 2A1VH@1|root,30Q4S@2|Bacteria,1WMIG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - SJTD3_k127_2458208_5 742823.HMPREF9465_00052 1.421e-29 133.0 COG0477@1|root,COG2814@2|Bacteria,1MUBP@1224|Proteobacteria,2VH9G@28216|Betaproteobacteria,4PQ9C@995019|Sutterellaceae 28216|Betaproteobacteria EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1,MFS_1_like,Sugar_tr SJTD3_k127_2458208_9 1045009.AFXQ01000038_gene226 1.049e-14 88.0 COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,1W8TR@1268|Micrococcaceae 201174|Actinobacteria O Subtilase family - - - - - - - - - - - - PA,Peptidase_S8,SLH SJTD3_k127_2458208_8 1121288.AULL01000016_gene880 3.893e-20 106.0 2AC0T@1|root,311IM@2|Bacteria,4PGCB@976|Bacteroidetes,1IH7K@117743|Flavobacteriia,3ZT8H@59732|Chryseobacterium 976|Bacteroidetes - - - - - - - - - - - - - - - SJTD3_k127_2458208_1 485913.Krac_7256 1.266e-127 413.0 COG0667@1|root,COG0667@2|Bacteria,2G5N6@200795|Chloroflexi 200795|Chloroflexi C PFAM aldo keto reductase - - - - - - - - - - - - Aldo_ket_red SJTD3_k127_2458208_0 748280.NH8B_2717 6.378e-139 456.0 COG2072@1|root,COG2072@2|Bacteria,1MWPJ@1224|Proteobacteria,2VKYW@28216|Betaproteobacteria 28216|Betaproteobacteria P fad dependent oxidoreductase - - - ko:K07222 - - - - ko00000 - - - Pyr_redox_3 SJTD3_k127_2465250_3 479434.Sthe_0323 3.595e-10 71.0 COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia 189775|Thermomicrobia S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO SJTD3_k127_2465250_2 1128421.JAGA01000003_gene3091 4.949e-36 158.0 COG4485@1|root,COG4485@2|Bacteria,2NP78@2323|unclassified Bacteria 2|Bacteria S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - YfhO SJTD3_k127_2465250_0 1051632.TPY_0754 1.407e-48 177.0 COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,24BQ6@186801|Clostridia 186801|Clostridia S PFAM Glycosyl transferase family 2 - - 2.4.1.83 ko:K00721,ko:K00786 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SJTD3_k127_249810_2 1382356.JQMP01000001_gene983 1.393e-53 198.0 2CDJQ@1|root,3304W@2|Bacteria,2G933@200795|Chloroflexi,27Z4Q@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - SJTD3_k127_249810_3 1449353.JQMQ01000005_gene688 5.313e-07 61.0 COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria,2NIBF@228398|Streptacidiphilus 201174|Actinobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi SJTD3_k127_249810_0 211165.AJLN01000153_gene660 2.931e-88 301.0 COG1595@1|root,COG1595@2|Bacteria,1G0NE@1117|Cyanobacteria,1JK91@1189|Stigonemataceae 1117|Cyanobacteria K Sigma-70 region 2 - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_249810_1 485913.Krac_3255 8.612e-85 294.0 COG1233@1|root,COG1233@2|Bacteria,2G8AW@200795|Chloroflexi 200795|Chloroflexi C Glucose inhibited division protein A - - - - - - - - - - - - Amino_oxidase SJTD3_k127_2504248_0 515635.Dtur_1563 2.965e-199 631.0 COG0495@1|root,COG0495@2|Bacteria 2|Bacteria J leucyl-tRNA aminoacylation leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_2300 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 SJTD3_k127_2508263_0 1536772.R70723_08390 8.457e-56 207.0 COG0491@1|root,COG0491@2|Bacteria,1V8JE@1239|Firmicutes,4HIYW@91061|Bacilli,26VD8@186822|Paenibacillaceae 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SJTD3_k127_2508263_1 485913.Krac_3903 5.225e-18 90.0 2EACU@1|root,334GQ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - F420H2_quin_red SJTD3_k127_2508263_2 1382356.JQMP01000003_gene2345 0.0006436 46.0 COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi,27XQX@189775|Thermomicrobia 189775|Thermomicrobia C Prephenate dehydrogenase - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH SJTD3_k127_2519030_1 1128421.JAGA01000002_gene991 8.7e-43 164.0 COG1793@1|root,COG1793@2|Bacteria,2NPKI@2323|unclassified Bacteria 2|Bacteria L ATP dependent DNA ligase C terminal region lig GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 ko:K10747 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00381,R00382,R10822,R10823 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N SJTD3_k127_2519030_2 1123226.KB899299_gene3389 2.29e-17 92.0 COG3861@1|root,COG3861@2|Bacteria,1V71H@1239|Firmicutes,4IRSD@91061|Bacilli,276WN@186822|Paenibacillaceae 91061|Bacilli S Heat induced stress protein YflT - - - - - - - - - - - - DUF2382,YflT SJTD3_k127_2519030_0 357808.RoseRS_0881 1.096e-80 281.0 COG1209@1|root,COG1209@2|Bacteria,2GBKU@200795|Chloroflexi,3781T@32061|Chloroflexia 32061|Chloroflexia M Nucleotidyl transferase - - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase SJTD3_k127_2519204_0 479434.Sthe_3245 7.692e-189 607.0 COG0474@1|root,COG0474@2|Bacteria,2G5ZS@200795|Chloroflexi 2|Bacteria P TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase SJTD3_k127_2526713_0 1128421.JAGA01000003_gene2708 4.034e-80 281.0 COG0438@1|root,COG0438@2|Bacteria,2NQV5@2323|unclassified Bacteria 2|Bacteria M Glycosyltransferase Family 4 - - 2.4.1.270 ko:K21369 - - - - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_2531531_2 324602.Caur_1943 2.325e-28 125.0 COG1989@1|root,COG1989@2|Bacteria,2G797@200795|Chloroflexi,375WX@32061|Chloroflexia 32061|Chloroflexia NOU PFAM peptidase A24A, prepilin type IV - - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 SJTD3_k127_2531531_3 471857.Svir_01380 2.197e-14 87.0 COG1287@1|root,COG1287@2|Bacteria,2GMZM@201174|Actinobacteria,4E0ZH@85010|Pseudonocardiales 201174|Actinobacteria S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_2531531_0 204669.Acid345_2243 2.565e-142 463.0 COG0436@1|root,COG0436@2|Bacteria,3Y3DG@57723|Acidobacteria,2JMAM@204432|Acidobacteriia 204432|Acidobacteriia E Aminotransferase class I and II - - - - - - - - - - - - Aminotran_1_2 SJTD3_k127_2531531_1 1460634.JCM19037_1241 1.866e-28 116.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli 91061|Bacilli G COG1363 Cellulase M and related proteins ysdC - - - - - - - - - - - Peptidase_M42 SJTD3_k127_2567117_1 357808.RoseRS_2149 5.42e-37 146.0 COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi,375E7@32061|Chloroflexia 32061|Chloroflexia U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 SJTD3_k127_2567117_2 316274.Haur_1454 8.675e-07 60.0 COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi,375FV@32061|Chloroflexia 32061|Chloroflexia U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - SJTD3_k127_2567117_0 891968.Anamo_1586 4.832e-266 839.0 COG0380@1|root,COG1877@1|root,COG0380@2|Bacteria,COG1877@2|Bacteria,3TA4P@508458|Synergistetes 508458|Synergistetes G PFAM glycosyl transferase family 20 - - 2.4.1.15,2.4.1.347,3.1.3.12 ko:K00697,ko:K16055 ko00500,ko01100,map00500,map01100 - R02737,R02778 RC00005,RC00017,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT20 - Glyco_transf_20,Trehalose_PPase SJTD3_k127_2570060_0 525904.Tter_1789 1.857e-282 887.0 COG1185@1|root,COG1185@2|Bacteria,2NNX7@2323|unclassified Bacteria 2|Bacteria J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 SJTD3_k127_2570060_1 1223543.GP2_007_00300 3.118e-29 121.0 COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4GEEC@85026|Gordoniaceae 201174|Actinobacteria J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 SJTD3_k127_2578013_1 479434.Sthe_3475 1.002e-84 295.0 COG0508@1|root,COG0508@2|Bacteria,2G7SG@200795|Chloroflexi,27XXQ@189775|Thermomicrobia 189775|Thermomicrobia C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) - - 2.3.1.168 ko:K09699 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R02662,R03174,R04097,R10998 RC00004,RC02727,RC02870 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding SJTD3_k127_2578013_0 485913.Krac_11168 5.745e-118 391.0 COG0320@1|root,COG0320@2|Bacteria,2G5MH@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives lipA GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 ko:K03644 ko00785,ko01100,map00785,map01100 - R07767,R07768 RC01978 ko00000,ko00001,ko01000 - - - LIAS_N,Radical_SAM SJTD3_k127_2578013_3 525904.Tter_0097 8.603e-58 209.0 COG0321@1|root,COG0321@2|Bacteria,2NPE7@2323|unclassified Bacteria 2|Bacteria H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate lipB GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 ko:K03644,ko:K03801 ko00785,ko01100,map00785,map01100 - R07766,R07767,R07768,R07769 RC00039,RC00992,RC01978,RC02867 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB SJTD3_k127_2578013_4 743719.PaelaDRAFT_2468 9.475e-35 148.0 COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,4HDGS@91061|Bacilli,276GU@186822|Paenibacillaceae 91061|Bacilli K Transcriptional regulator, LysR family - - - - - - - - - - - - HTH_1,LysR_substrate SJTD3_k127_2578013_2 316274.Haur_0963 7.697e-59 209.0 COG0084@1|root,COG0084@2|Bacteria,2G6F2@200795|Chloroflexi,375AZ@32061|Chloroflexia 32061|Chloroflexia L TIGRFAM hydrolase, TatD family - - - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase SJTD3_k127_2580379_1 1243664.CAVL020000028_gene102 4.01e-14 83.0 COG1404@1|root,COG3103@1|root,COG5492@1|root,COG1404@2|Bacteria,COG3103@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - Peptidase_M43,Reprolysin_4,SH3_3,SLH,fn3 SJTD3_k127_2580379_0 909613.UO65_2013 4.655e-119 412.0 COG1404@1|root,COG1404@2|Bacteria,2IEGJ@201174|Actinobacteria,4DXZF@85010|Pseudonocardiales 201174|Actinobacteria O Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CARDB,CarboxypepD_reg,Malectin,Peptidase_S8 SJTD3_k127_25841_0 479434.Sthe_0073 1.446e-42 160.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process - - - - - - - - - - - - Ribonuc_L-PSP SJTD3_k127_25841_2 861299.J421_5702 6.137e-07 57.0 COG4454@1|root,COG4454@2|Bacteria,1ZTKN@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - SJTD3_k127_258420_6 1217718.ALOU01000093_gene1738 2.807e-06 51.0 COG2217@1|root,COG2217@2|Bacteria,1MU08@1224|Proteobacteria,2VH8J@28216|Betaproteobacteria,1K311@119060|Burkholderiaceae 28216|Betaproteobacteria P ATPase, P-type (transporting), HAD superfamily, subfamily IC copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase SJTD3_k127_258420_3 1382306.JNIM01000001_gene1432 1.441e-25 108.0 COG1937@1|root,COG1937@2|Bacteria,2G7H9@200795|Chloroflexi 200795|Chloroflexi S Metal-sensitive transcriptional repressor - - - ko:K21600 - - - - ko00000,ko03000 - - - Trns_repr_metal SJTD3_k127_258420_0 29540.C481_02312 2.416e-69 239.0 COG1651@1|root,arCOG02868@2157|Archaea,2XW8R@28890|Euryarchaeota,23U3Q@183963|Halobacteria 183963|Halobacteria OP DSBA-like thioredoxin domain - - - - - - - - - - - - Thioredoxin_4 SJTD3_k127_258420_1 751944.HALDL1_11380 2.276e-66 234.0 COG1225@1|root,arCOG00310@2157|Archaea,2XUM4@28890|Euryarchaeota,23UT5@183963|Halobacteria 183963|Halobacteria O alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen hyrA2 - - - - - - - - - - - AhpC-TSA SJTD3_k127_258420_5 1278073.MYSTI_04734 4.997e-07 61.0 COG0695@1|root,COG0695@2|Bacteria,1QX55@1224|Proteobacteria,43BXV@68525|delta/epsilon subdivisions,2X78N@28221|Deltaproteobacteria,2Z3E0@29|Myxococcales 28221|Deltaproteobacteria O Glutaredoxin-like domain (DUF836) - - - - - - - - - - - - DUF836 SJTD3_k127_258420_2 357808.RoseRS_4484 7.545e-30 132.0 COG3815@1|root,COG3815@2|Bacteria,2G73B@200795|Chloroflexi 200795|Chloroflexi O Predicted membrane protein (DUF2085) - - - - - - - - - - - - DUF2085 SJTD3_k127_258420_4 446468.Ndas_5009 1.906e-15 79.0 COG0785@1|root,COG0785@2|Bacteria,2GJW3@201174|Actinobacteria,4EHWN@85012|Streptosporangiales 201174|Actinobacteria O Cytochrome C biogenesis protein transmembrane region ccdA - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - DsbD SJTD3_k127_260372_3 926550.CLDAP_11940 7.528e-12 78.0 COG4745@1|root,COG4745@2|Bacteria,2G8SI@200795|Chloroflexi 2|Bacteria O Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_260372_2 926550.CLDAP_16790 2.47e-46 181.0 COG2129@1|root,COG2129@2|Bacteria,2G8MC@200795|Chloroflexi 200795|Chloroflexi S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos SJTD3_k127_260372_1 1128421.JAGA01000001_gene2083 4.599e-87 300.0 COG1475@1|root,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria 2|Bacteria K DNA binding - - - - - - - - - - - - DUF4032,ParBc SJTD3_k127_260372_0 485913.Krac_3332 1.242e-180 602.0 COG0841@1|root,COG0841@2|Bacteria,2G68V@200795|Chloroflexi 200795|Chloroflexi V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - ko:K03296 - - - - ko00000 2.A.6.2 - - ACR_tran SJTD3_k127_2613992_1 1128421.JAGA01000002_gene1335 2.956e-148 490.0 COG0593@1|root,COG0593@2|Bacteria,2NNTK@2323|unclassified Bacteria 2|Bacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N SJTD3_k127_2613992_2 261292.Nit79A3_2983 4.925e-34 135.0 COG0662@1|root,COG0662@2|Bacteria,1N71F@1224|Proteobacteria,2W4YS@28216|Betaproteobacteria,373E5@32003|Nitrosomonadales 28216|Betaproteobacteria G AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_2613992_0 497964.CfE428DRAFT_5133 1.206e-150 495.0 COG1164@1|root,COG1164@2|Bacteria,46UYB@74201|Verrucomicrobia 74201|Verrucomicrobia E Peptidase family M3 - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3 SJTD3_k127_2613992_7 67275.JOAP01000037_gene3003 2.787e-15 88.0 COG2310@1|root,COG2340@1|root,COG2310@2|Bacteria,COG2340@2|Bacteria,2GNN0@201174|Actinobacteria 201174|Actinobacteria T Cysteine-rich secretory protein family - - - - - - - - - - - - CAP,TerD SJTD3_k127_2613992_4 680646.RMDY18_18820 1.072e-21 108.0 COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,1W8TR@1268|Micrococcaceae 201174|Actinobacteria O Subtilase family - - - - - - - - - - - - Big_3_5,PA,Peptidase_S8,SLH,fn3_5 SJTD3_k127_2613992_6 1445613.JALM01000017_gene5932 6.646e-19 98.0 COG0491@1|root,COG0491@2|Bacteria,2GMHY@201174|Actinobacteria,4E2QR@85010|Pseudonocardiales 201174|Actinobacteria S Metallo-beta-lactamase superfamily blaB3 - - - - - - - - - - - Lactamase_B SJTD3_k127_2613992_5 926560.KE387023_gene2387 1.757e-20 97.0 COG0662@1|root,COG0662@2|Bacteria,1WN48@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Protein of unknown function (DUF861) - - - - - - - - - - - - Cupin_2 SJTD3_k127_2613992_3 926550.CLDAP_08070 2.275e-32 134.0 COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi 200795|Chloroflexi S PFAM RDD domain containing protein - - - - - - - - - - - - RDD SJTD3_k127_262274_4 485913.Krac_4435 2.345e-12 70.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 SJTD3_k127_262274_1 1416759.AYMR01000007_gene619 4.52e-83 285.0 COG0596@1|root,COG0596@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds - - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_262274_0 1210884.HG799465_gene11434 6.904e-125 411.0 2C57D@1|root,2Z7RS@2|Bacteria,2IZEG@203682|Planctomycetes 203682|Planctomycetes S Protein of unknown function (DUF2891) - - - - - - - - - - - - DUF2891 SJTD3_k127_262274_2 661478.OP10G_3856 4.996e-35 139.0 293YG@1|root,2ZRDH@2|Bacteria 2|Bacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 SJTD3_k127_262274_3 500153.JOEK01000009_gene5062 2.005e-21 96.0 COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_2639904_2 35754.JNYJ01000003_gene6468 4.396e-11 68.0 2ES3U@1|root,33JNT@2|Bacteria,2GPSP@201174|Actinobacteria,4DJRZ@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_2639904_1 485913.Krac_8954 3.495e-12 77.0 COG0477@1|root,COG0477@2|Bacteria,2G5UF@200795|Chloroflexi 200795|Chloroflexi EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1 SJTD3_k127_2639904_0 574087.Acear_1860 7.014e-69 241.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3WABC@53433|Halanaerobiales 186801|Clostridia G Belongs to the pyruvate kinase family pyk - 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C SJTD3_k127_2651409_0 1312954.KI914846_gene1771 1.035e-39 152.0 COG5485@1|root,COG5485@2|Bacteria 2|Bacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL SJTD3_k127_2651409_1 383372.Rcas_1047 7.351e-12 79.0 COG1807@1|root,COG1807@2|Bacteria,2GBKP@200795|Chloroflexi,377PV@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase family 39 - - - - - - - - - - - - PMT SJTD3_k127_2651409_2 926550.CLDAP_20400 7.071e-09 57.0 COG2151@1|root,COG2151@2|Bacteria,2G75C@200795|Chloroflexi 200795|Chloroflexi S Pfam:DUF59 - - - - - - - - - - - - FeS_assembly_P SJTD3_k127_2659881_0 479434.Sthe_2271 0.0003183 53.0 COG5305@1|root,COG5305@2|Bacteria,2G7AA@200795|Chloroflexi 200795|Chloroflexi S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_2660450_3 504728.K649_06070 1.227e-12 68.0 COG0346@1|root,COG0346@2|Bacteria,1WICF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E glyoxalase bleomycin resistance protein dioxygenase - - - ko:K15975 - - - - ko00000 - - - Glyoxalase SJTD3_k127_2660450_2 1243664.CAVL020000019_gene3581 4.282e-29 134.0 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZBKV@1386|Bacillus 91061|Bacilli L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Excalibur,HHH_3,LTD,Lactamase_B,SLH SJTD3_k127_2660450_1 1183438.GKIL_2106 4.051e-67 252.0 COG4447@1|root,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - CBM_2 SJTD3_k127_2660450_4 446468.Ndas_2747 2.853e-07 55.0 COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4EGA7@85012|Streptosporangiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_2660450_0 926569.ANT_15860 1.341e-92 326.0 COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi 200795|Chloroflexi M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - DUF2298,PMT_2,TPR_16,TPR_19,TPR_8 SJTD3_k127_2665740_1 1382359.JIAL01000001_gene2085 1.079e-75 262.0 COG1228@1|root,COG1228@2|Bacteria,3Y3BK@57723|Acidobacteria,2JKVY@204432|Acidobacteriia 204432|Acidobacteriia Q Amidohydrolase family hutI - 3.5.2.7 ko:K01468 ko00340,ko01100,map00340,map01100 M00045 R02288 RC00683 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 SJTD3_k127_2665740_0 1449126.JQKL01000011_gene3588 1.863e-88 304.0 COG4448@1|root,COG4448@2|Bacteria,1TRWI@1239|Firmicutes,24CUE@186801|Clostridia,268US@186813|unclassified Clostridiales 186801|Clostridia E L-asparaginase II - - - - - - - - - - - - Asparaginase_II SJTD3_k127_2665740_2 383372.Rcas_1798 1.18e-46 176.0 COG4122@1|root,COG4122@2|Bacteria,2G9CA@200795|Chloroflexi,37638@32061|Chloroflexia 32061|Chloroflexia S PFAM O-methyltransferase, family 3 - - - - - - - - - - - - Methyltransf_3 SJTD3_k127_2665740_3 1382306.JNIM01000001_gene2677 2.542e-32 130.0 COG4012@1|root,COG4012@2|Bacteria,2G6IF@200795|Chloroflexi 200795|Chloroflexi S Putative pyruvate format-lyase activating enzyme (DUF1786) - - - - - - - - - - - - DUF1786 SJTD3_k127_2668500_0 1297863.APJF01000021_gene124 1.906e-227 745.0 COG0210@1|root,COG0210@2|Bacteria,1MZGR@1224|Proteobacteria,2TSRX@28211|Alphaproteobacteria,3K2IW@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria L IrrE N-terminal-like domain - - - - - - - - - - - - PDDEXK_1,Peptidase_M78,UvrD-helicase,UvrD_C SJTD3_k127_2668500_2 365044.Pnap_2445 0.0001822 52.0 28MGI@1|root,2ZATR@2|Bacteria,1R5N2@1224|Proteobacteria,2VS74@28216|Betaproteobacteria,4AHQQ@80864|Comamonadaceae 28216|Betaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_2668500_1 78245.Xaut_0774 1.874e-09 68.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_2673490_1 316274.Haur_3169 5.36e-17 81.0 COG2208@1|root,COG2208@2|Bacteria,2G6HM@200795|Chloroflexi,375D4@32061|Chloroflexia 32061|Chloroflexia KT PFAM Stage II sporulation E family protein - - - - - - - - - - - - SpoIIE SJTD3_k127_2673490_0 485913.Krac_7311 3.297e-57 214.0 COG3021@1|root,COG3021@2|Bacteria,2G9DW@200795|Chloroflexi 200795|Chloroflexi S PFAM Endonuclease Exonuclease phosphatase - - - - - - - - - - - - Exo_endo_phos SJTD3_k127_2679105_2 471853.Bcav_0262 9.566e-30 121.0 COG0662@1|root,COG0662@2|Bacteria,2IP1J@201174|Actinobacteria 201174|Actinobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_2679105_1 1121022.ABENE_18090 4.025e-42 164.0 COG4430@1|root,COG4430@2|Bacteria,1N8ME@1224|Proteobacteria,2UT29@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Domain of unknown function (DUF1905) - - - - - - - - - - - - DUF1905,OmdA SJTD3_k127_2679105_4 1157637.KB892102_gene1295 1.183e-08 63.0 COG0346@1|root,COG0346@2|Bacteria,2IHYP@201174|Actinobacteria 201174|Actinobacteria E glyoxalase bleomycin resistance protein dioxygenase - - - - - - - - - - - - Glyoxalase SJTD3_k127_2679105_0 485913.Krac_0922 1.655e-44 164.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - Cupin_2 SJTD3_k127_2679105_3 1298858.AUEL01000006_gene2072 4.493e-23 102.0 2D579@1|root,32TID@2|Bacteria,1RH2N@1224|Proteobacteria,2U9TR@28211|Alphaproteobacteria,43M58@69277|Phyllobacteriaceae 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_2698265_1 211165.AJLN01000062_gene3868 4.194e-48 181.0 COG2949@1|root,COG2949@2|Bacteria,1G297@1117|Cyanobacteria,1JKYS@1189|Stigonemataceae 1117|Cyanobacteria S DUF218 domain - - - - - - - - - - - - DUF218 SJTD3_k127_2698265_0 479434.Sthe_1163 9.831e-105 361.0 COG0768@1|root,COG0768@2|Bacteria,2G7V1@200795|Chloroflexi,27XRU@189775|Thermomicrobia 189775|Thermomicrobia M Penicillin binding protein transpeptidase domain - - - ko:K05364 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01011 - - - Transpeptidase SJTD3_k127_2698265_2 324602.Caur_3893 1.497e-37 143.0 COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi,37557@32061|Chloroflexia 32061|Chloroflexia D Belongs to the SEDS family - - - - - - - - - - - - FTSW_RODA_SPOVE SJTD3_k127_2700779_0 1128421.JAGA01000003_gene3559 3.253e-73 267.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_2700779_1 316274.Haur_3182 1.984e-41 169.0 COG0249@1|root,COG0249@2|Bacteria,2G8CJ@200795|Chloroflexi 200795|Chloroflexi L PFAM DNA mismatch repair protein MutS domain protein - - - - - - - - - - - - MutS_V SJTD3_k127_2701914_0 1521187.JPIM01000028_gene1598 4.216e-28 122.0 COG1216@1|root,COG1216@2|Bacteria,2GAH6@200795|Chloroflexi,377WE@32061|Chloroflexia 32061|Chloroflexia S PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 SJTD3_k127_2701914_1 768671.ThimaDRAFT_3239 1.406e-19 103.0 COG2244@1|root,COG2244@2|Bacteria,1PF64@1224|Proteobacteria,1TKCZ@1236|Gammaproteobacteria,1X1Y8@135613|Chromatiales 135613|Chromatiales S polysaccharide biosynthetic process - - - - - - - - - - - - - SJTD3_k127_2701914_2 1173020.Cha6605_4684 4.292e-14 75.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4 SJTD3_k127_2709755_2 479434.Sthe_1293 2.857e-57 205.0 COG0015@1|root,COG0015@2|Bacteria,2G607@200795|Chloroflexi,27XJC@189775|Thermomicrobia 189775|Thermomicrobia F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily - - 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - - ADSL_C,Lyase_1 SJTD3_k127_2709755_0 401526.TcarDRAFT_1257 1.364e-100 345.0 COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,4H2GA@909932|Negativicutes 909932|Negativicutes J tRNA methylthiotransferase YqeV yqeV - 2.8.4.5 ko:K18707 - - R10649 RC00003,RC03221 ko00000,ko01000,ko03016 - - - Radical_SAM,UPF0004 SJTD3_k127_2709755_1 485913.Krac_11482 8.261e-83 292.0 COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi 2|Bacteria C PFAM Cytochrome P450 - - - - - - - - - - - - p450 SJTD3_k127_271646_2 1128421.JAGA01000001_gene2172 1.398e-64 237.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_271646_0 326427.Cagg_1401 1.635e-83 293.0 COG0438@1|root,COG0438@2|Bacteria,2GABS@200795|Chloroflexi,3752C@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_271646_1 765420.OSCT_1591 2.942e-81 302.0 COG1807@1|root,COG1807@2|Bacteria,2G8SF@200795|Chloroflexi,3757N@32061|Chloroflexia 32061|Chloroflexia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - SJTD3_k127_2723486_1 485913.Krac_9101 1.201e-29 124.0 COG0789@1|root,COG0789@2|Bacteria 2|Bacteria K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - - - - - - - - - - MerR_1 SJTD3_k127_2723486_0 357808.RoseRS_1013 1.242e-55 213.0 COG1752@1|root,COG1752@2|Bacteria 2|Bacteria M Esterase of the alpha-beta hydrolase superfamily suhR GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - Patatin SJTD3_k127_2751204_0 1121377.KB906424_gene3959 5.889e-28 129.0 COG2771@1|root,COG3903@1|root,COG2771@2|Bacteria,COG3903@2|Bacteria 2|Bacteria K ADP binding - - - ko:K21405 - - - - ko00000,ko03000 - - - AAA_16,AAA_22,BTAD,DUF4019,GerE,NB-ARC,TPR_12 SJTD3_k127_276453_1 756067.MicvaDRAFT_2554 1.07e-11 66.0 COG0642@1|root,COG3447@1|root,COG4251@1|root,COG2205@2|Bacteria,COG3447@2|Bacteria,COG4251@2|Bacteria,1G2I4@1117|Cyanobacteria,1H7VC@1150|Oscillatoriales 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,HATPase_c,HisKA,MASE1,PAS_3,PAS_9 SJTD3_k127_276453_0 1385935.N836_19770 2.321e-90 314.0 COG0465@1|root,COG0465@2|Bacteria,1G22Z@1117|Cyanobacteria,1H7W7@1150|Oscillatoriales 1117|Cyanobacteria O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 SJTD3_k127_2809154_1 1128421.JAGA01000002_gene1616 2.066e-23 105.0 COG1300@1|root,COG1300@2|Bacteria 2|Bacteria CP Membrane - - - ko:K06384 - - - - ko00000 - - - SpoIIM SJTD3_k127_2809154_0 1128421.JAGA01000002_gene1057 4.664e-118 394.0 COG1721@1|root,COG1721@2|Bacteria 2|Bacteria E protein (some members contain a von Willebrand factor type A (vWA) domain - - - - - - - - - - - - DUF11,DUF58 SJTD3_k127_2819654_1 1313172.YM304_27830 1.092e-57 207.0 COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria 201174|Actinobacteria C Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase SJTD3_k127_2819654_0 479434.Sthe_0354 6.632e-111 367.0 COG0277@1|root,COG2141@1|root,COG0277@2|Bacteria,COG2141@2|Bacteria,2G7JT@200795|Chloroflexi,27YZZ@189775|Thermomicrobia 189775|Thermomicrobia C FAD binding domain - - - - - - - - - - - - Bac_luciferase,FAD_binding_4 SJTD3_k127_2833020_0 479434.Sthe_1588 1.741e-122 419.0 COG1305@1|root,COG1305@2|Bacteria,2G66M@200795|Chloroflexi,27XNH@189775|Thermomicrobia 189775|Thermomicrobia E Transglutaminase/protease-like homologues - - - - - - - - - - - - DUF4129,Transglut_core SJTD3_k127_2833020_1 479434.Sthe_1589 2.726e-109 372.0 COG1721@1|root,COG1721@2|Bacteria,2G5XH@200795|Chloroflexi,27XZ3@189775|Thermomicrobia 189775|Thermomicrobia S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 SJTD3_k127_2833020_2 1382356.JQMP01000004_gene62 1.036e-36 141.0 COG0714@1|root,COG0714@2|Bacteria,2G66D@200795|Chloroflexi,27XT7@189775|Thermomicrobia 189775|Thermomicrobia S ATPase family associated with various cellular activities (AAA) - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SJTD3_k127_283368_2 1047013.AQSP01000144_gene828 2.953e-09 64.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4,Glyco_transf_11,Methyltransf_21 SJTD3_k127_283368_0 1128421.JAGA01000002_gene1117 1.341e-72 269.0 COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria 2|Bacteria L Glycosyltransferase like family 2 gumK - 2.4.1.264 ko:K07011,ko:K13659 - - R09732 RC00005,RC00049 ko00000,ko01000,ko01003 - GT70 - Glyco_tranf_2_3,Glyco_trans_1_4,Glycos_transf_1,Glycos_transf_2 SJTD3_k127_283368_1 264732.Moth_0408 4.253e-65 226.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,42EVI@68295|Thermoanaerobacterales 186801|Clostridia H PFAM GTP cyclohydrolase I Nitrile oxidoreductase folE - 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI SJTD3_k127_2834333_2 525904.Tter_0337 4.136e-30 123.0 COG3695@1|root,COG3695@2|Bacteria,2NRVD@2323|unclassified Bacteria 2|Bacteria L 6-O-methylguanine DNA methyltransferase, DNA binding domain ybaZ GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 ko:K00567,ko:K07443 - - - - ko00000,ko01000,ko03400 - - - DNA_binding_1 SJTD3_k127_2834333_4 479434.Sthe_1604 2.561e-09 58.0 COG0222@1|root,COG0222@2|Bacteria,2G700@200795|Chloroflexi,27YF7@189775|Thermomicrobia 189775|Thermomicrobia J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N SJTD3_k127_2834333_3 926567.TheveDRAFT_0259 2.261e-27 113.0 COG0222@1|root,COG0222@2|Bacteria,3TB80@508458|Synergistetes 508458|Synergistetes J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N SJTD3_k127_2834333_1 572479.Hprae_1697 2.988e-36 149.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WANA@53433|Halanaerobiales 186801|Clostridia J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ - - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 SJTD3_k127_2834333_0 1120950.KB892776_gene793 1.482e-56 209.0 COG2021@1|root,COG2021@2|Bacteria,2GIZI@201174|Actinobacteria,4DVIS@85009|Propionibacteriales 201174|Actinobacteria E alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_2834333_5 383372.Rcas_0195 1.231e-08 59.0 COG0457@1|root,COG0457@2|Bacteria,2GB3M@200795|Chloroflexi,377UW@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723 SJTD3_k127_2864237_4 864702.OsccyDRAFT_2164 2.17e-09 58.0 COG2013@1|root,COG2013@2|Bacteria,1G2XX@1117|Cyanobacteria,1H7NB@1150|Oscillatoriales 1117|Cyanobacteria S TIGRFAM TIGR00266 family protein - - - - - - - - - - - - AIM24 SJTD3_k127_2864237_3 1382306.JNIM01000001_gene2947 8.478e-23 102.0 COG3324@1|root,COG3324@2|Bacteria 2|Bacteria E translation initiation factor activity - - - - - - - - - - - - Glyoxalase SJTD3_k127_2864237_0 869210.Marky_1927 7.678e-188 599.0 COG0076@1|root,COG0076@2|Bacteria,1WKXN@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E COG0076 Glutamate decarboxylase and related PLP-dependent - - 4.1.1.105,4.1.1.28 ko:K01593 ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034 M00037,M00042 R00685,R00699,R00736,R02080,R02701,R04909 RC00299 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC SJTD3_k127_2864237_1 485913.Krac_4939 8.327e-87 299.0 COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi 200795|Chloroflexi S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L SJTD3_k127_2864237_2 215803.DB30_7610 6.958e-42 172.0 COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales 28221|Deltaproteobacteria MU PKD domain - - - - - - - - - - - - PKD SJTD3_k127_2870938_0 1128421.JAGA01000003_gene3453 5.892e-229 720.0 COG0405@1|root,COG0405@2|Bacteria,2NP14@2323|unclassified Bacteria 2|Bacteria E Gamma-glutamyltranspeptidase ggt GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 - R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935 RC00064,RC00090,RC00096 ko00000,ko00001,ko01000,ko01002 - - - G_glu_transpept SJTD3_k127_2870938_1 1128421.JAGA01000003_gene3419 3.34e-119 389.0 COG2141@1|root,COG2141@2|Bacteria,2NQM2@2323|unclassified Bacteria 2|Bacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_2887260_2 485913.Krac_2557 4.112e-22 98.0 COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi 200795|Chloroflexi P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import - - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM,PDGLE SJTD3_k127_2887260_1 1382306.JNIM01000001_gene3634 7.756e-104 344.0 COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi 200795|Chloroflexi P TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ cbiQ - - ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiQ SJTD3_k127_2887260_0 1382306.JNIM01000001_gene3633 1.559e-120 393.0 COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi 200795|Chloroflexi P ABC transporter - - - ko:K02006 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - ABC_tran SJTD3_k127_2889543_1 324602.Caur_3019 3.003e-68 244.0 COG1284@1|root,COG1284@2|Bacteria,2G6SY@200795|Chloroflexi,376F0@32061|Chloroflexia 32061|Chloroflexia S Uncharacterized protein conserved in bacteria (DUF2179) - - - - - - - - - - - - DUF2179,YitT_membrane SJTD3_k127_2889543_0 1242864.D187_003557 1.07e-97 329.0 COG0665@1|root,COG0665@2|Bacteria,1NCJX@1224|Proteobacteria,431XD@68525|delta/epsilon subdivisions,2WWSZ@28221|Deltaproteobacteria,2YUQQ@29|Myxococcales 28221|Deltaproteobacteria E FAD dependent oxidoreductase - - 1.4.3.3 ko:K00273 ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146 - R00366,R02457,R02894,R02923,R04221,R07400 RC00006,RC00018,RC00135 ko00000,ko00001,ko01000 - - - DAO SJTD3_k127_2889543_2 649639.Bcell_1278 5.353e-47 171.0 COG0624@1|root,COG0624@2|Bacteria,1TQS9@1239|Firmicutes,4HDHW@91061|Bacilli,1ZBDC@1386|Bacillus 91061|Bacilli E Acetylornithine deacetylase yodQ - 3.5.1.16,3.5.1.18 ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R00669,R02734,R09107 RC00064,RC00090,RC00300 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 SJTD3_k127_2897057_1 1206733.BAGC01000043_gene838 1.97e-68 241.0 COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4FWU2@85025|Nocardiaceae 201174|Actinobacteria E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB2 - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP SJTD3_k127_2897057_0 479434.Sthe_1218 9.639e-104 350.0 COG0728@1|root,COG0728@2|Bacteria,2G5MD@200795|Chloroflexi,27XGY@189775|Thermomicrobia 189775|Thermomicrobia S Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane - - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN SJTD3_k127_292879_1 582515.KR51_00011320 3.421e-48 175.0 COG0662@1|root,COG0662@2|Bacteria,1G5PK@1117|Cyanobacteria 1117|Cyanobacteria G PFAM Cupin domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_292879_0 47839.CCAU010000011_gene5282 2.158e-65 236.0 COG2141@1|root,COG2141@2|Bacteria,2GJI7@201174|Actinobacteria,23AVQ@1762|Mycobacteriaceae 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_2937072_0 867845.KI911784_gene3417 1.658e-58 215.0 COG2723@1|root,COG2723@2|Bacteria,2GBIH@200795|Chloroflexi,3771Z@32061|Chloroflexia 32061|Chloroflexia G 6-phospho-beta-galactosidase activity - - - - - - - - - - - - FlaA,Glyco_hydro_42,Glyco_hydro_cc SJTD3_k127_2937072_1 266779.Meso_2970 4.328e-28 119.0 COG2057@1|root,COG2057@2|Bacteria,1MY3S@1224|Proteobacteria,2TUZ8@28211|Alphaproteobacteria,43Q70@69277|Phyllobacteriaceae 28211|Alphaproteobacteria I Coenzyme A transferase - - 2.8.3.12 ko:K01040 ko00643,ko00650,ko01120,map00643,map00650,map01120 - R04000,R05509 RC00012,RC00131,RC00137 ko00000,ko00001,ko01000 - - - CoA_trans SJTD3_k127_2941022_0 867845.KI911784_gene1817 2.117e-74 258.0 COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,376TC@32061|Chloroflexia 32061|Chloroflexia K Two component transcriptional regulator, winged helix family - - - ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SJTD3_k127_2941022_1 479434.Sthe_1940 4.835e-54 213.0 COG0642@1|root,COG2205@2|Bacteria,2GAAW@200795|Chloroflexi,27Z8B@189775|Thermomicrobia 189775|Thermomicrobia T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA SJTD3_k127_2949767_2 525904.Tter_1613 2.823e-81 281.0 COG0770@1|root,COG0770@2|Bacteria,2NP4Q@2323|unclassified Bacteria 2|Bacteria M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SJTD3_k127_2949767_0 479434.Sthe_1996 5.878e-114 389.0 COG0768@1|root,COG0768@2|Bacteria,2G66C@200795|Chloroflexi,27Y3G@189775|Thermomicrobia 189775|Thermomicrobia M Penicillin-binding Protein dimerisation domain - - 3.4.16.4 ko:K03587 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011,ko03036 - - - PBP_dimer,Transpeptidase SJTD3_k127_2949767_4 1128421.JAGA01000002_gene1032 0.0002535 50.0 2DR6K@1|root,33AE2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - FtsL SJTD3_k127_2949767_1 357808.RoseRS_3778 1.951e-97 330.0 COG0275@1|root,COG0275@2|Bacteria,2G658@200795|Chloroflexi,374SY@32061|Chloroflexia 32061|Chloroflexia J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 SJTD3_k127_2949767_3 537013.CLOSTMETH_03317 7.525e-06 49.0 COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WJCZ@541000|Ruminococcaceae 186801|Clostridia K Belongs to the MraZ family mraZ - - ko:K03925 - - - - ko00000 - - - MraZ SJTD3_k127_2959128_0 439235.Dalk_3862 3.45e-97 332.0 COG0438@1|root,COG0438@2|Bacteria,1MY5T@1224|Proteobacteria,42NYR@68525|delta/epsilon subdivisions,2WJB1@28221|Deltaproteobacteria,2MM2E@213118|Desulfobacterales 28221|Deltaproteobacteria M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_2959128_3 562970.Btus_1039 1.101e-10 72.0 COG0596@1|root,COG0596@2|Bacteria,1VRHA@1239|Firmicutes,4IQ6T@91061|Bacilli,278RD@186823|Alicyclobacillaceae 91061|Bacilli S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 SJTD3_k127_2959128_1 1403313.AXBR01000005_gene1870 9.175e-66 237.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli,1ZCGF@1386|Bacillus 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family glnH - - ko:K09969,ko:K10039 ko02010,map02010 M00228,M00232 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 SJTD3_k127_2959128_2 1463821.JOGR01000009_gene1766 3.345e-24 106.0 COG0765@1|root,COG0765@2|Bacteria,2GNUR@201174|Actinobacteria,4EZ4J@85014|Glycomycetales 201174|Actinobacteria E Binding-protein-dependent transport system inner membrane component - - - ko:K10006 ko02010,map02010 M00233 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.9 - - BPD_transp_1 SJTD3_k127_2967150_0 479434.Sthe_0159 0.0 1272.0 COG1112@1|root,COG2251@1|root,COG1112@2|Bacteria,COG2251@2|Bacteria,2G7US@200795|Chloroflexi,27YN6@189775|Thermomicrobia 189775|Thermomicrobia L PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - AAA_11,AAA_12,PDDEXK_1 SJTD3_k127_2967150_8 648996.Theam_0408 1.216e-22 104.0 2CFGB@1|root,33Y5M@2|Bacteria,2G51A@200783|Aquificae 200783|Aquificae - - - - - - - - - - - - - - - SJTD3_k127_2967150_4 935866.JAER01000034_gene3617 9.753e-36 147.0 COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4DNS9@85009|Propionibacteriales 201174|Actinobacteria T helix_turn_helix, Lux Regulon - - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg SJTD3_k127_2967150_1 485913.Krac_2926 5.927e-125 436.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulator, LuxR family - - - - - - - - - - - - AAA_22,GerE,NB-ARC,TPR_12 SJTD3_k127_2967150_6 1286631.X805_35580 3.908e-26 110.0 COG0724@1|root,COG0724@2|Bacteria,1N6VR@1224|Proteobacteria,2VRC4@28216|Betaproteobacteria,1KKP8@119065|unclassified Burkholderiales 28216|Betaproteobacteria S RNA-binding protein - - - - - - - - - - - - RRM_1 SJTD3_k127_2967150_3 383372.Rcas_4227 9.488e-81 274.0 COG2197@1|root,COG2197@2|Bacteria,2G6T1@200795|Chloroflexi,376HK@32061|Chloroflexia 32061|Chloroflexia K Two component transcriptional regulator, LuxR family - - - - - - - - - - - - GerE,Response_reg SJTD3_k127_2967150_7 383372.Rcas_4228 2.407e-25 110.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - ko:K07689 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 M00475 - - ko00000,ko00001,ko00002,ko02022 - - - Biotin_lipoyl_2,HlyD_3,HlyD_D23,Response_reg SJTD3_k127_2967150_5 1128421.JAGA01000001_gene2343 1.884e-31 130.0 COG1996@1|root,COG1996@2|Bacteria 2|Bacteria K Psort location Cytoplasmic, score - - - - - - - - - - - - DUF4379 SJTD3_k127_2967150_2 1128421.JAGA01000001_gene2344 1.976e-87 314.0 COG4907@1|root,COG4907@2|Bacteria,2NQC3@2323|unclassified Bacteria 2|Bacteria S Predicted membrane protein (DUF2207) yciQ GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - DUF2207 SJTD3_k127_2967150_9 926569.ANT_20600 3.955e-19 100.0 arCOG05710@1|root,33AIT@2|Bacteria,2G9CR@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - SJTD3_k127_2967473_0 525904.Tter_1791 3.854e-84 291.0 COG0392@1|root,COG0392@2|Bacteria,2NQTH@2323|unclassified Bacteria 2|Bacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SJTD3_k127_2967473_1 1128421.JAGA01000003_gene3584 2.465e-48 178.0 COG0615@1|root,COG0615@2|Bacteria,2NPMA@2323|unclassified Bacteria 2|Bacteria IM Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - 2.7.1.167,2.7.7.70 ko:K03272 ko00540,ko01100,map00540,map01100 M00064 R05644,R05646 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko01005 - - - CTP_transf_like,PfkB SJTD3_k127_2967895_1 926550.CLDAP_08070 1.294e-44 172.0 COG1714@1|root,COG1714@2|Bacteria,2G7CB@200795|Chloroflexi 200795|Chloroflexi S PFAM RDD domain containing protein - - - - - - - - - - - - RDD SJTD3_k127_2967895_0 357808.RoseRS_3801 7.316e-47 177.0 COG1300@1|root,COG1300@2|Bacteria,2G8HV@200795|Chloroflexi,37546@32061|Chloroflexia 32061|Chloroflexia S Stage II sporulation protein M - - - - - - - - - - - - SpoIIM SJTD3_k127_2972100_1 479434.Sthe_2169 4.173e-55 218.0 COG2979@1|root,COG2979@2|Bacteria,2GBAG@200795|Chloroflexi,27YIA@189775|Thermomicrobia 189775|Thermomicrobia S Protein of unknown function (DUF533) - - - - - - - - - - - - - SJTD3_k127_2972100_2 1382306.JNIM01000001_gene1256 1.036e-47 177.0 COG0632@1|root,COG0632@2|Bacteria,2G6V7@200795|Chloroflexi 200795|Chloroflexi L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N SJTD3_k127_2972100_3 357808.RoseRS_1634 3.729e-38 151.0 COG0424@1|root,COG0424@2|Bacteria,2G6U2@200795|Chloroflexi,375PQ@32061|Chloroflexia 32061|Chloroflexia D PFAM Maf family protein - - - ko:K06287 - - - - ko00000 - - - Maf SJTD3_k127_2972100_0 485913.Krac_12488 1.387e-86 298.0 COG0635@1|root,COG0635@2|Bacteria,2G5NK@200795|Chloroflexi 200795|Chloroflexi H Involved in the biosynthesis of porphyrin-containing compound hemN - - - - - - - - - - - HemN_C,Radical_SAM SJTD3_k127_2972480_4 1304880.JAGB01000001_gene966 1.833e-46 173.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia 186801|Clostridia E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA - 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase SJTD3_k127_2972480_3 926550.CLDAP_21740 2.073e-63 227.0 COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi 200795|Chloroflexi E NAD-dependent glycerol-3-phosphate dehydrogenase domain protein - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH SJTD3_k127_2972480_0 926569.ANT_01870 6.078e-134 435.0 COG2876@1|root,COG2876@2|Bacteria,2G643@200795|Chloroflexi 200795|Chloroflexi E PFAM DAHP synthetase I KDSA - - 2.5.1.54 ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - - DAHP_synth_1 SJTD3_k127_2972480_5 1128421.JAGA01000003_gene3433 2.482e-31 128.0 COG4401@1|root,COG4401@2|Bacteria 2|Bacteria E Chorismate mutase type I aroH GO:0003674,GO:0003824,GO:0004106,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046417,GO:0071704 2.7.4.25,5.4.99.5 ko:K00945,ko:K06208 ko00240,ko00400,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map01100,map01110,map01130,map01230 M00024,M00025,M00052 R00158,R00512,R01665,R01715 RC00002,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_1 SJTD3_k127_2972480_2 1229780.BN381_70023 6.881e-79 267.0 COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,3UWPF@52018|unclassified Actinobacteria (class) 201174|Actinobacteria EH Peptidase C26 trpG GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986,R01716 RC00010,RC01418,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase SJTD3_k127_2972480_1 309801.trd_0102 1.629e-128 422.0 COG0147@1|root,COG0147@2|Bacteria,2G5M7@200795|Chloroflexi,27XZ8@189775|Thermomicrobia 189775|Thermomicrobia H Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE - 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind SJTD3_k127_2978615_1 479434.Sthe_0017 4.819e-18 95.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - 3.4.21.50 ko:K01337,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002 - - - DUF4397,Peptidase_S8,Trypsin_2 SJTD3_k127_2978615_2 479434.Sthe_0016 1.203e-17 90.0 2CIIT@1|root,3033V@2|Bacteria,2GBC0@200795|Chloroflexi,27YQM@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - SJTD3_k127_2978615_0 525904.Tter_1768 1.548e-107 356.0 2DBIJ@1|root,2Z9G2@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - Phage_capsid SJTD3_k127_2978615_3 525904.Tter_1770 7.808e-09 61.0 2DCSV@1|root,2ZF7N@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_2986439_1 357808.RoseRS_2436 1.299e-12 70.0 COG1195@1|root,COG1195@2|Bacteria,2G60N@200795|Chloroflexi,375E0@32061|Chloroflexia 32061|Chloroflexia L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N SJTD3_k127_2986439_0 479434.Sthe_3485 1.25e-217 686.0 COG1239@1|root,COG1239@2|Bacteria,2GB7G@200795|Chloroflexi,27XRK@189775|Thermomicrobia 189775|Thermomicrobia H Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - 6.6.1.1 ko:K03405 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R03877 RC01012 ko00000,ko00001,ko01000 - - - - SJTD3_k127_2989864_1 1907.SGLAU_07630 3.37e-37 144.0 COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria 201174|Actinobacteria S Protein of unknown function DUF72 - - - - - - - - - - - - DUF72 SJTD3_k127_2989864_2 485913.Krac_1496 4.008e-35 136.0 COG1146@1|root,COG1146@2|Bacteria,2G75G@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - Fer4,Fer4_4 SJTD3_k127_2989864_0 525904.Tter_2663 3.535e-156 502.0 COG2059@1|root,COG2059@2|Bacteria,2NPUT@2323|unclassified Bacteria 2|Bacteria P Chromate transporter chrA - - ko:K07240 - - - - ko00000,ko02000 2.A.51.1 - - Chromate_transp SJTD3_k127_2989864_3 383372.Rcas_1811 2.129e-11 67.0 COG0001@1|root,COG0001@2|Bacteria,2G7UK@200795|Chloroflexi,376S9@32061|Chloroflexia 32061|Chloroflexia H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 5.4.3.8 ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 M00121 R02272 RC00677 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SJTD3_k127_3012054_2 479434.Sthe_1254 1.151e-70 248.0 COG0391@1|root,COG0391@2|Bacteria,2G5MJ@200795|Chloroflexi,27XU0@189775|Thermomicrobia 189775|Thermomicrobia S Required for morphogenesis under gluconeogenic growth conditions - - - - - - - - - - - - UPF0052 SJTD3_k127_3012054_0 479434.Sthe_1253 6.233e-157 501.0 COG0057@1|root,COG0057@2|Bacteria,2G5MG@200795|Chloroflexi,27Y38@189775|Thermomicrobia 189775|Thermomicrobia C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family - - 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N SJTD3_k127_3012054_1 1521187.JPIM01000012_gene1662 2.514e-150 485.0 COG0126@1|root,COG0126@2|Bacteria,2G5UE@200795|Chloroflexi,3757X@32061|Chloroflexia 32061|Chloroflexia F Belongs to the phosphoglycerate kinase family pgk - 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGK SJTD3_k127_3012054_3 1507.HMPREF0262_02667 4.181e-20 100.0 COG0526@1|root,COG0785@1|root,COG0526@2|Bacteria,COG0785@2|Bacteria,1TQH1@1239|Firmicutes,249IS@186801|Clostridia,36FFI@31979|Clostridiaceae 186801|Clostridia O Cytochrome c biogenesis protein transmembrane region - - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - AhpC-TSA,DsbD,Redoxin SJTD3_k127_3012054_4 42256.RradSPS_0034 5.694e-09 61.0 COG2259@1|root,COG2259@2|Bacteria 2|Bacteria S methylamine metabolic process mauE - - - - - - - - - - - MauE SJTD3_k127_3019185_2 1128421.JAGA01000002_gene607 1.069e-23 104.0 COG0240@1|root,COG0240@2|Bacteria,2NP1N@2323|unclassified Bacteria 2|Bacteria I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N SJTD3_k127_3019185_1 351160.RCIX50 1.175e-31 136.0 COG1277@1|root,arCOG02436@2157|Archaea 2157|Archaea S ABC-type transport system involved in multi-copper enzyme maturation, permease nosY2 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_2 SJTD3_k127_3019185_0 351160.RCIX51 4.683e-121 399.0 COG1131@1|root,arCOG00194@2157|Archaea,2XT0T@28890|Euryarchaeota 28890|Euryarchaeota E ABC-type multidrug transport system ATPase component - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_3021109_2 1382356.JQMP01000003_gene2374 1.685e-21 98.0 COG1208@1|root,COG1208@2|Bacteria,2G5KH@200795|Chloroflexi,27XSX@189775|Thermomicrobia 189775|Thermomicrobia M Nucleotidyl transferase - - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase SJTD3_k127_3021109_0 324602.Caur_1839 9.626e-99 335.0 COG2264@1|root,COG2264@2|Bacteria,2G69X@200795|Chloroflexi,374X2@32061|Chloroflexia 32061|Chloroflexia J Methylates ribosomal protein L11 prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA SJTD3_k127_3021109_1 1128421.JAGA01000002_gene285 7.588e-48 185.0 COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase, family 9 - - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SJTD3_k127_302436_2 477641.MODMU_4202 0.0001959 44.0 COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4EVFM@85013|Frankiales 201174|Actinobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 SJTD3_k127_302436_3 445975.COLSTE_00812 0.0003341 44.0 COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4CV6B@84998|Coriobacteriia 84998|Coriobacteriia Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1 SJTD3_k127_302436_1 211165.AJLN01000047_gene6121 2.362e-08 63.0 COG4803@1|root,COG4803@2|Bacteria,1GJPE@1117|Cyanobacteria,1JJCG@1189|Stigonemataceae 1117|Cyanobacteria S Protein of unknown function (DUF1269) - - - - - - - - - - - - DUF1269 SJTD3_k127_302436_0 1043205.AFYF01000083_gene1849 3.344e-16 87.0 COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4FG0C@85021|Intrasporangiaceae 201174|Actinobacteria E Amidinotransferase arcA - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf SJTD3_k127_3039150_1 309801.trd_0688 1.308e-84 288.0 COG1624@1|root,COG1624@2|Bacteria,2G6J7@200795|Chloroflexi,27XJ7@189775|Thermomicrobia 189775|Thermomicrobia S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA - - - - - - - - - - - DisA_N SJTD3_k127_3039150_0 765420.OSCT_2820 3.326e-127 447.0 COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi,374UJ@32061|Chloroflexia 32061|Chloroflexia S SMART Tetratricopeptide domain protein - - - - - - - - - - - - TPR_16,TPR_19,TPR_4,TPR_6,TPR_7,TPR_8 SJTD3_k127_3040089_0 525904.Tter_0032 1.528e-197 638.0 COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria 2|Bacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 SJTD3_k127_3040089_1 1128421.JAGA01000002_gene63 1.625e-07 61.0 COG2755@1|root,COG2755@2|Bacteria,2NR75@2323|unclassified Bacteria 2|Bacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 SJTD3_k127_3041814_0 926550.CLDAP_10900 1.118e-44 180.0 COG1376@1|root,COG1388@1|root,COG1376@2|Bacteria,COG1388@2|Bacteria,2G6ZY@200795|Chloroflexi 200795|Chloroflexi M PFAM ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - LysM,YkuD SJTD3_k127_3041814_3 268407.PWYN_08530 7.234e-09 68.0 COG1388@1|root,COG1388@2|Bacteria,1VQSM@1239|Firmicutes,4HZ24@91061|Bacilli,26ZS9@186822|Paenibacillaceae 91061|Bacilli M Lysin motif - - - - - - - - - - - - LysM SJTD3_k127_3041814_1 1121377.KB906401_gene3530 4.478e-41 163.0 COG3173@1|root,COG3173@2|Bacteria 2|Bacteria S very-long-chain-acyl-CoA dehydrogenase activity - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - APH SJTD3_k127_3041814_2 765420.OSCT_2919 2.405e-19 92.0 COG0709@1|root,COG0709@2|Bacteria,2G5W4@200795|Chloroflexi 200795|Chloroflexi H Synthesizes selenophosphate from selenide and ATP selD - 2.7.9.3 ko:K01008 ko00450,ko01100,map00450,map01100 - R03595 RC00002,RC02878 ko00000,ko00001,ko01000,ko03016 - - - AIRS,AIRS_C SJTD3_k127_3045396_7 1380394.JADL01000011_gene3794 1.28e-06 54.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2TQZM@28211|Alphaproteobacteria,2JWUB@204441|Rhodospirillales 204441|Rhodospirillales C Inorganic pyrophosphatase - - - - - - - - - - - - Pyrophosphatase SJTD3_k127_3045396_6 321327.CYA_2409 4.871e-19 92.0 COG1308@1|root,COG1308@2|Bacteria,1G83N@1117|Cyanobacteria,1H3C4@1129|Synechococcus 1117|Cyanobacteria K Domain of unknown function (DUF4342) - - - - - - - - - - - - DUF4342 SJTD3_k127_3045396_4 518766.Rmar_1010 1.313e-92 317.0 COG0778@1|root,COG0778@2|Bacteria,4NQ04@976|Bacteroidetes 976|Bacteroidetes C Nitroreductase - - - - - - - - - - - - Nitroreductase SJTD3_k127_3045396_0 1122221.JHVI01000016_gene1617 3.876e-140 457.0 COG0479@1|root,COG0479@2|Bacteria 2|Bacteria C Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family asrA - - ko:K16950 ko00920,ko01120,map00920,map01120 - R00858,R10146 RC00065 ko00000,ko00001 - - - Fer4_22 SJTD3_k127_3045396_5 272134.KB731324_gene5861 8.097e-47 174.0 COG0664@1|root,COG0664@2|Bacteria 2|Bacteria T cyclic nucleotide binding crp - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding SJTD3_k127_3045396_3 518766.Rmar_2588 7.228e-104 345.0 COG0543@1|root,COG0543@2|Bacteria 2|Bacteria C 2 iron, 2 sulfur cluster binding asrB - - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - - DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 SJTD3_k127_3045396_1 518766.Rmar_2589 8.485e-119 388.0 COG1941@1|root,COG1941@2|Bacteria 2|Bacteria C coenzyme F420 hydrogenase activity hoxY - - - - - - - - - - - Oxidored_q6 SJTD3_k127_3045396_2 247490.KSU1_A0077 6.16e-117 385.0 COG3259@1|root,COG3259@2|Bacteria,2IYS2@203682|Planctomycetes 203682|Planctomycetes C Nickel-dependent hydrogenase - - - - - - - - - - - - NiFeSe_Hases SJTD3_k127_3049111_3 316274.Haur_1699 1.812e-31 129.0 COG4635@1|root,COG4635@2|Bacteria,2G739@200795|Chloroflexi,377J0@32061|Chloroflexia 32061|Chloroflexia CH Flavodoxin domain - - 1.3.5.3 ko:K00230 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R09489 RC00885 ko00000,ko00001,ko00002,ko01000 - - - Flavodoxin_5 SJTD3_k127_3049111_1 319225.Plut_0242 1.839e-58 222.0 COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi 1090|Chlorobi M PFAM glycosyl transferase family 2 - - - ko:K14597 ko00906,map00906 - R07544,R07546 RC00262 ko00000,ko00001 - - - Glyco_tranf_2_3,Glycos_transf_2 SJTD3_k127_3049111_2 326427.Cagg_0152 1.506e-45 176.0 COG0204@1|root,COG0204@2|Bacteria,2GAE1@200795|Chloroflexi,375Q3@32061|Chloroflexia 32061|Chloroflexia I PFAM phospholipid glycerol acyltransferase - - - - - - - - - - - - Acyltransferase SJTD3_k127_3049111_0 765420.OSCT_0163 1.526e-118 393.0 COG1233@1|root,COG1233@2|Bacteria,2G68M@200795|Chloroflexi,376AV@32061|Chloroflexia 32061|Chloroflexia Q PFAM amine oxidase - - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 - R04787,R04798,R04800,R09691,R09692 RC01214,RC02088,RC02605 ko00000,ko00001,ko01000 - - - Amino_oxidase SJTD3_k127_3055823_2 272562.CA_C0918 2.225e-28 124.0 COG3934@1|root,COG3934@2|Bacteria,1VREH@1239|Firmicutes,24EG3@186801|Clostridia,36GPZ@31979|Clostridiaceae 186801|Clostridia G dockerin type - - - - - - - - - - - - Cellulase,Dockerin_1,Glyco_hydro_2_C SJTD3_k127_3055823_0 309801.trd_1069 2.748e-36 151.0 COG0500@1|root,COG2226@2|Bacteria,2G780@200795|Chloroflexi,27XQ2@189775|Thermomicrobia 189775|Thermomicrobia Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_3055823_1 932677.PAJ_1257 5.057e-33 139.0 COG2931@1|root,COG2931@2|Bacteria,1MU7T@1224|Proteobacteria 1224|Proteobacteria Q COG2931, RTX toxins and related Ca2 -binding proteins - - - - - - - - - - - - DUF4214,FecR,He_PIG,HemolysinCabind,VCBS,VWA SJTD3_k127_3057848_0 1306990.BARG01000092_gene9024 4.628e-61 220.0 COG1222@1|root,COG1401@1|root,COG1222@2|Bacteria,COG1401@2|Bacteria,2GM1I@201174|Actinobacteria 201174|Actinobacteria V associated with various cellular activities - - - ko:K07452 - - - - ko00000,ko01000,ko02048 - - - AAA_5 SJTD3_k127_3057848_2 1449347.JQLN01000004_gene6274 1.122e-33 145.0 COG4268@1|root,COG4268@2|Bacteria,2GKET@201174|Actinobacteria,2M5ZR@2063|Kitasatospora 201174|Actinobacteria V McrBC 5-methylcytosine restriction system component - - - ko:K19147 - - - - ko00000,ko02048 - - - McrBC SJTD3_k127_3057848_1 402777.KB235904_gene3740 5.885e-39 166.0 COG2202@1|root,COG2461@1|root,COG4191@1|root,COG2202@2|Bacteria,COG2461@2|Bacteria,COG4191@2|Bacteria,1G3EQ@1117|Cyanobacteria,1H7E6@1150|Oscillatoriales 1117|Cyanobacteria T PAS PAC sensor signal transduction histidine kinase - - - - - - - - - - - - HATPase_c,HisKA,PAS_9 SJTD3_k127_306342_1 357808.RoseRS_3759 1.91e-25 115.0 COG1287@1|root,COG1287@2|Bacteria,2G8T3@200795|Chloroflexi,376JU@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_306342_0 479435.Kfla_2275 4.26e-103 340.0 2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4DR0C@85009|Propionibacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_3064111_3 485913.Krac_12603 1.854e-95 318.0 COG0702@1|root,COG0702@2|Bacteria 2|Bacteria GM epimerase - - - - - - - - - - - - NAD_binding_10,RmlD_sub_bind SJTD3_k127_3064111_0 485913.Krac_12604 1.825e-144 463.0 COG1595@1|root,COG1595@2|Bacteria,2G7NX@200795|Chloroflexi 200795|Chloroflexi K COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_3064111_14 7029.ACYPI005528-PA 4.765e-09 70.0 KOG4441@1|root,KOG4441@2759|Eukaryota,38CWG@33154|Opisthokonta,3BH03@33208|Metazoa,3D1IW@33213|Bilateria,41XID@6656|Arthropoda,3SH7V@50557|Insecta,3E7T0@33342|Paraneoptera 33208|Metazoa T Kelch motif KLHL18 GO:0000151,GO:0002009,GO:0002165,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006807,GO:0007275,GO:0007444,GO:0007552,GO:0007560,GO:0008092,GO:0008150,GO:0008152,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0016567,GO:0019538,GO:0031461,GO:0031463,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0035239,GO:0035295,GO:0036211,GO:0042802,GO:0042803,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046528,GO:0046529,GO:0046983,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048856,GO:0051865,GO:0060429,GO:0060562,GO:0070647,GO:0071704,GO:1901564,GO:1902494,GO:1990234 - ko:K10455 - - - - ko00000,ko04121 - - - BACK,BTB,Kelch_1 SJTD3_k127_3064111_12 65497.JODV01000002_gene4148 2.124e-12 81.0 COG1404@1|root,COG1404@2|Bacteria,2IEGJ@201174|Actinobacteria,4DXZF@85010|Pseudonocardiales 201174|Actinobacteria O Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CARDB,CarboxypepD_reg,Malectin,Peptidase_S8 SJTD3_k127_3064111_13 1285586.H131_03229 3.617e-09 71.0 COG0737@1|root,COG0737@2|Bacteria,1V9N4@1239|Firmicutes,4HJBW@91061|Bacilli,3IXST@400634|Lysinibacillus 91061|Bacilli F S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_3064111_6 1304284.L21TH_0109 1.075e-62 220.0 COG0317@1|root,COG0317@2|Bacteria,1VAH0@1239|Firmicutes,24MVX@186801|Clostridia,36JIN@31979|Clostridiaceae 186801|Clostridia KT HD domain - - - - - - - - - - - - HD_4 SJTD3_k127_3064111_9 204669.Acid345_0078 4.485e-21 103.0 COG5424@1|root,COG5424@2|Bacteria,3Y7HA@57723|Acidobacteria,2JMUU@204432|Acidobacteriia 204432|Acidobacteriia H Iron-containing redox enzyme - - 1.3.3.11 ko:K06137 - - - - ko00000,ko01000 - - - Haem_oxygenas_2 SJTD3_k127_3064111_1 1128421.JAGA01000001_gene2176 7.187e-123 402.0 COG2141@1|root,COG2141@2|Bacteria,2NQMQ@2323|unclassified Bacteria 2|Bacteria C PFAM Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_3064111_11 1449357.JQLK01000001_gene1739 1.997e-13 81.0 2BVRK@1|root,2ZCUH@2|Bacteria,1WMAJ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - SJTD3_k127_3064111_5 1274524.BSONL12_12056 3.137e-78 278.0 COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,4H9VB@91061|Bacilli,1ZDX4@1386|Bacillus 91061|Bacilli S COG2270 Permeases of the major facilitator superfamily yxiO - - ko:K06902 ko04138,map04138 - - - ko00000,ko00001,ko02000,ko04131 2.A.1.24,9.A.15.1 - - ATG22 SJTD3_k127_3064111_2 926550.CLDAP_04910 3.35e-106 353.0 COG0837@1|root,COG0837@2|Bacteria,2G7R9@200795|Chloroflexi 200795|Chloroflexi H Belongs to the bacterial glucokinase family glk - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Glucokinase SJTD3_k127_3064111_7 309801.trd_A0782 2.677e-36 151.0 COG3764@1|root,COG3764@2|Bacteria,2G70I@200795|Chloroflexi,27Y5J@189775|Thermomicrobia 189775|Thermomicrobia M peptidase C60 sortase A and B - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase SJTD3_k127_3064111_4 1382306.JNIM01000001_gene1603 1.151e-79 278.0 COG1159@1|root,COG3597@1|root,COG1159@2|Bacteria,COG3597@2|Bacteria,2G9CM@200795|Chloroflexi 200795|Chloroflexi S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism - - - - - - - - - - - - DUF697,MMR_HSR1 SJTD3_k127_3064111_8 1128421.JAGA01000002_gene1062 4.077e-35 152.0 COG5180@1|root,COG5180@2|Bacteria,2NRZJ@2323|unclassified Bacteria 2|Bacteria A pathogenesis CP_0034 - - ko:K02417,ko:K02519 ko02030,ko02040,map02030,map02040 - - - ko00000,ko00001,ko02035,ko02044,ko03012,ko03029 3.A.6.2,3.A.6.3 - - GPDPase_memb SJTD3_k127_3064111_10 383372.Rcas_2512 1.844e-14 86.0 2EQIM@1|root,33I4N@2|Bacteria,2G9B7@200795|Chloroflexi,3773Z@32061|Chloroflexia 32061|Chloroflexia S Domain of unknown function (DUF4129) - - - - - - - - - - - - DUF4129 SJTD3_k127_3068123_2 383372.Rcas_0950 1.163e-133 430.0 COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi,376MS@32061|Chloroflexia 32061|Chloroflexia I PFAM carboxyl transferase - - - - - - - - - - - - Carboxyl_trans SJTD3_k127_3068123_4 357808.RoseRS_3693 3.853e-24 111.0 COG4770@1|root,COG4770@2|Bacteria,2GBMU@200795|Chloroflexi,3782K@32061|Chloroflexia 32061|Chloroflexia I PFAM biotin lipoyl attachment domain-containing protein - - - - - - - - - - - - Biotin_lipoyl SJTD3_k127_3068123_1 357808.RoseRS_3692 2.62e-176 558.0 COG1883@1|root,COG1883@2|Bacteria,2G7ZJ@200795|Chloroflexi,3768I@32061|Chloroflexia 32061|Chloroflexia C PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit - - 4.1.1.3 ko:K01572 ko00620,ko01100,map00620,map01100 - R00217 RC00040 ko00000,ko00001,ko01000,ko02000 3.B.1.1.1 - - OAD_beta SJTD3_k127_3068123_0 526227.Mesil_0165 7.901e-177 562.0 COG0446@1|root,COG0446@2|Bacteria,1WI8N@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S FAD-dependent pyridine nucleotide-disulfide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 SJTD3_k127_3068123_3 481448.Minf_2156 3.105e-28 117.0 COG0425@1|root,COG0425@2|Bacteria,46YZR@74201|Verrucomicrobia,37GVP@326457|unclassified Verrucomicrobia 74201|Verrucomicrobia O Sulfurtransferase TusA - - - - - - - - - - - - TusA SJTD3_k127_3068123_5 926560.KE387023_gene2053 5.682e-06 48.0 COG2210@1|root,COG2210@2|Bacteria 2|Bacteria P Belongs to the sulfur carrier protein TusA family - - - - - - - - - - - - DrsE,DrsE_2 SJTD3_k127_3071081_2 644966.Tmar_0019 4.079e-12 75.0 2EF3G@1|root,338WJ@2|Bacteria,1VHUW@1239|Firmicutes,24R77@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - SJTD3_k127_3071081_1 298654.FraEuI1c_1503 5.618e-83 287.0 COG4974@1|root,COG4974@2|Bacteria,2HTVG@201174|Actinobacteria,4EUVH@85013|Frankiales 201174|Actinobacteria L Phage integrase family - - - - - - - - - - - - Phage_int_SAM_4,Phage_integrase SJTD3_k127_3071081_0 745776.DGo_CA2326 8.285e-142 461.0 COG1226@1|root,COG1226@2|Bacteria 2|Bacteria P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) dMI1 - 3.1.4.46 ko:K01126,ko:K10716 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Castor_Poll_mid,TrkA_N SJTD3_k127_3072394_0 926550.CLDAP_24510 2.448e-242 772.0 COG2273@1|root,COG2273@2|Bacteria,2G7RY@200795|Chloroflexi 200795|Chloroflexi G Glycoside hydrolase family 16 - - - - - - - - - - - - Glyco_hydro_16 SJTD3_k127_3072394_2 485913.Krac_11116 3.637e-33 137.0 COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi 200795|Chloroflexi K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_3072394_4 96561.Dole_2414 1.265e-06 62.0 COG0457@1|root,COG0457@2|Bacteria,1NNJ6@1224|Proteobacteria,42PBD@68525|delta/epsilon subdivisions,2WKWJ@28221|Deltaproteobacteria,2MPUH@213118|Desulfobacterales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - PMT_2,TPR_1,TPR_11,TPR_2,TPR_7,TPR_8 SJTD3_k127_3072394_1 1382306.JNIM01000001_gene2761 2.576e-143 458.0 COG1809@1|root,COG1809@2|Bacteria 2|Bacteria S phosphosulfolactate synthase activity - - - - - - - - - - - - ComA SJTD3_k127_3072394_3 929712.KI912613_gene2224 4.448e-07 58.0 COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4CQMC@84995|Rubrobacteria 84995|Rubrobacteria O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SJTD3_k127_3072394_5 1463926.JOCA01000002_gene5636 0.0002688 44.0 COG1985@1|root,COG1985@2|Bacteria 2|Bacteria H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate ribD - 1.1.1.193,3.5.4.26 ko:K00082,ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 M00125 R03458,R03459 RC00204,RC00933 ko00000,ko00001,ko00002,ko01000 - - - RibD_C SJTD3_k127_3078145_0 1118054.CAGW01000024_gene451 7.909e-76 260.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli,26SYE@186822|Paenibacillaceae 91061|Bacilli E peptidase M20 dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20 SJTD3_k127_3078145_1 497964.CfE428DRAFT_0042 3.298e-63 231.0 COG1073@1|root,COG1073@2|Bacteria,46T3P@74201|Verrucomicrobia 74201|Verrucomicrobia S Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4 SJTD3_k127_3078145_2 479434.Sthe_3455 1.15e-62 236.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2G5WM@200795|Chloroflexi,27Y7Y@189775|Thermomicrobia 200795|Chloroflexi DM Capsular exopolysaccharide family - - 2.7.10.2 ko:K08253 - - - - ko00000,ko01000 - - - CbiA,GNVR,Wzz SJTD3_k127_3078145_3 370438.PTH_2565 4.982e-60 223.0 COG0438@1|root,COG0438@2|Bacteria,1TPY6@1239|Firmicutes,24834@186801|Clostridia,261PX@186807|Peptococcaceae 186801|Clostridia M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_3079393_0 469383.Cwoe_5488 6.401e-05 56.0 COG1807@1|root,COG1807@2|Bacteria,2GVIK@201174|Actinobacteria,4CQCI@84995|Rubrobacteria 84995|Rubrobacteria M Predicted membrane protein (DUF2142) - - - - - - - - - - - - DUF2142 SJTD3_k127_3089454_1 1128421.JAGA01000002_gene40 1.385e-128 424.0 COG2379@1|root,COG2379@2|Bacteria,2NNQP@2323|unclassified Bacteria 2|Bacteria G MOFRL family - - 2.7.1.165 ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 M00346 R08572 RC00002,RC00428 ko00000,ko00001,ko00002,ko01000 - - - DUF4147,MOFRL SJTD3_k127_3089454_0 316274.Haur_4461 1.098e-173 563.0 COG1543@1|root,COG1543@2|Bacteria,2GBQW@200795|Chloroflexi,3764R@32061|Chloroflexia 32061|Chloroflexia G Belongs to the glycosyl hydrolase 57 family - - 2.4.1.18 ko:K16149 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000 - GH57 - DUF1957,Glyco_hydro_57 SJTD3_k127_3094000_5 1137268.AZXF01000004_gene2385 0.0002187 46.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2GK7P@201174|Actinobacteria 201174|Actinobacteria K iron dependent repressor sirR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA SJTD3_k127_3094000_2 366602.Caul_4677 2.497e-16 89.0 2EBTV@1|root,335TD@2|Bacteria,1NJ6B@1224|Proteobacteria,2UVZF@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_3094000_0 1192034.CAP_7461 1.759e-260 827.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKWS@28221|Deltaproteobacteria 28221|Deltaproteobacteria GT Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N SJTD3_k127_3094000_1 661478.OP10G_4125 1.317e-57 206.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - 2.3.1.128,2.3.1.82 ko:K00663,ko:K03790 - - - - ko00000,ko01000,ko01504,ko03009 - - - Acetyltransf_3 SJTD3_k127_3094000_3 525904.Tter_2790 6.732e-16 80.0 2CA4F@1|root,33DCB@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_3095478_0 926569.ANT_27750 6.1e-109 358.0 COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi 200795|Chloroflexi P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran SJTD3_k127_3095478_3 237368.SCABRO_01122 6.716e-76 262.0 COG0704@1|root,COG0704@2|Bacteria,2IYX4@203682|Planctomycetes 203682|Planctomycetes P Plays a role in the regulation of phosphate uptake - - - ko:K02039 - - - - ko00000 - - - PhoU SJTD3_k127_3095478_1 886293.Sinac_3852 6.036e-81 276.0 COG0412@1|root,COG0412@2|Bacteria 2|Bacteria Q carboxymethylenebutenolidase activity - - 3.1.1.45 ko:K01061,ko:K07100 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH SJTD3_k127_3095478_2 886293.Sinac_3851 2.07e-79 278.0 COG1926@1|root,COG1926@2|Bacteria,2J36S@203682|Planctomycetes 203682|Planctomycetes F Phosphoribosyl transferase domain - - - ko:K07100 - - - - ko00000 - - - Pribosyltran SJTD3_k127_3099347_1 1128421.JAGA01000001_gene2123 5.681e-31 135.0 COG5002@1|root,COG5002@2|Bacteria,2NR3P@2323|unclassified Bacteria 2|Bacteria T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07653 ko02020,map02020 M00460 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA SJTD3_k127_3099347_0 1382306.JNIM01000001_gene3358 7.469e-81 278.0 COG0745@1|root,COG0745@2|Bacteria,2G7VA@200795|Chloroflexi 200795|Chloroflexi K PFAM response regulator receiver - - - - - - - - - - - - Response_reg,Trans_reg_C SJTD3_k127_3099347_2 1122182.KB903836_gene5021 4.816e-17 94.0 COG1413@1|root,COG1413@2|Bacteria,2GKP6@201174|Actinobacteria,4DC90@85008|Micromonosporales 201174|Actinobacteria C lyase activity - - - - - - - - - - - - HEAT_2 SJTD3_k127_3101209_0 330214.NIDE1190 7.11e-34 139.0 COG1262@1|root,COG1262@2|Bacteria,3J14J@40117|Nitrospirae 2|Bacteria S Evidence 4 Homologs of previously reported genes of - - - - - - - - - - - - FGE-sulfatase SJTD3_k127_3101209_1 1131269.AQVV01000007_gene1029 4.042e-31 137.0 COG1262@1|root,COG1262@2|Bacteria 2|Bacteria T PFAM Formylglycine-generating sulfatase enzyme - - - - - - - - - - - - FGE-sulfatase SJTD3_k127_310515_5 858215.Thexy_1675 9.473e-19 100.0 COG4447@1|root,COG4447@2|Bacteria,1VG3Z@1239|Firmicutes,24TQ1@186801|Clostridia,42ITE@68295|Thermoanaerobacterales 186801|Clostridia S protein related to plant photosystem II stability assembly factor - - - - - - - - - - - - PSII_BNR SJTD3_k127_310515_3 1243664.CAVL020000019_gene3581 1.3e-20 109.0 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZBKV@1386|Bacillus 91061|Bacilli L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Excalibur,HHH_3,LTD,Lactamase_B,SLH SJTD3_k127_310515_2 935845.JADQ01000015_gene3242 2.601e-65 257.0 COG3291@1|root,COG3468@1|root,COG3291@2|Bacteria,COG3468@2|Bacteria 2|Bacteria MU cell adhesion - - - - - - - - - - - - Collagen,PKD,SBBP SJTD3_k127_310515_0 1444711.CCJF01000005_gene546 4.175e-147 521.0 COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_5,Calx-beta,SBBP SJTD3_k127_310515_1 927677.ALVU02000004_gene4738 2.625e-144 491.0 COG3903@1|root,COG3903@2|Bacteria 2|Bacteria K ADP binding - - - - - - - - - - - - AAA_22,DUF4062,NB-ARC,TPR_12 SJTD3_k127_310515_4 1146883.BLASA_1623 4.144e-19 92.0 COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria,4ET60@85013|Frankiales 201174|Actinobacteria S DUF218 domain - - - - - - - - - - - - DUF218 SJTD3_k127_3106757_3 383372.Rcas_1618 6.421e-07 59.0 COG1287@1|root,COG1287@2|Bacteria,2GA82@200795|Chloroflexi,375J6@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - PMT_2 SJTD3_k127_3106757_2 479434.Sthe_0949 8.912e-27 113.0 COG3870@1|root,COG3870@2|Bacteria,2G736@200795|Chloroflexi,27YHY@189775|Thermomicrobia 189775|Thermomicrobia S Cyclic-di-AMP receptor - - - - - - - - - - - - CdAMP_rec SJTD3_k127_3106757_1 867845.KI911784_gene873 6.624e-40 152.0 COG0143@1|root,COG0143@2|Bacteria,2G6VG@200795|Chloroflexi,375Q2@32061|Chloroflexia 32061|Chloroflexia J Double zinc ribbon - - - - - - - - - - - - DZR SJTD3_k127_3106757_0 1379270.AUXF01000001_gene2472 1.507e-86 294.0 COG1162@1|root,COG1162@2|Bacteria,1ZSSQ@142182|Gemmatimonadetes 142182|Gemmatimonadetes S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase SJTD3_k127_3114167_4 309801.trd_1645 1.626e-07 53.0 2A4W8@1|root,30THX@2|Bacteria,2GBFW@200795|Chloroflexi,27ZCE@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - SJTD3_k127_3114167_0 525904.Tter_1890 9.832e-147 481.0 28MN1@1|root,2ZAXN@2|Bacteria 2|Bacteria S Terminase-like family - - - - - - - - - - - - Terminase_6C SJTD3_k127_3114167_3 316274.Haur_0954 3.662e-24 107.0 COG3832@1|root,COG3832@2|Bacteria,2G9IK@200795|Chloroflexi 200795|Chloroflexi S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 SJTD3_k127_3114167_1 1173028.ANKO01000193_gene5867 1.862e-62 228.0 COG0515@1|root,COG2319@1|root,COG0515@2|Bacteria,COG2319@2|Bacteria,1G4N6@1117|Cyanobacteria 1117|Cyanobacteria KLT Serine Threonine protein kinase - - - - - - - - - - - - Pkinase,WD40 SJTD3_k127_3114167_2 525904.Tter_1769 2.379e-26 118.0 COG3567@1|root,COG3567@2|Bacteria 2|Bacteria F Phage-associated protein, HI1409 family - - - - - - - - - - - - DUF1073,Phage_prot_Gp6 SJTD3_k127_3114694_0 323850.Shew_3239 1.61e-120 411.0 COG2373@1|root,COG3055@1|root,COG3386@1|root,COG2373@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,1N85X@1224|Proteobacteria,1T3ZR@1236|Gammaproteobacteria,2QEVC@267890|Shewanellaceae 1224|Proteobacteria M PFAM Na-Ca exchanger integrin-beta4 - - - - - - - - - - - - - SJTD3_k127_3114694_1 1145276.T479_08195 1.211e-06 56.0 COG2911@1|root,COG3209@1|root,COG4632@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG4632@2|Bacteria,1UK8Y@1239|Firmicutes 1239|Firmicutes M Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - - - - - - - - - - Big_4,Flg_new,LRR_5 SJTD3_k127_3123794_4 411684.HPDFL43_00011360 4.105e-61 217.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2V7DA@28211|Alphaproteobacteria,43P68@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - - - - - - - - - - BPD_transp_2 SJTD3_k127_3123794_0 1174528.JH992893_gene5997 3.089e-186 589.0 COG2017@1|root,COG2017@2|Bacteria,1GGS7@1117|Cyanobacteria 1117|Cyanobacteria G converts alpha-aldose to the beta-anomer - - - - - - - - - - - - - SJTD3_k127_3123794_2 886293.Sinac_1080 3.101e-68 238.0 COG0800@1|root,COG0800@2|Bacteria,2IXBP@203682|Planctomycetes 203682|Planctomycetes G PFAM KDPG and KHG aldolase - - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase SJTD3_k127_3123794_5 388401.RB2150_09934 9.736e-56 205.0 COG0684@1|root,COG0684@2|Bacteria,1MW9P@1224|Proteobacteria,2TTGT@28211|Alphaproteobacteria,3ZHU8@58840|unclassified Rhodobacteraceae 28211|Alphaproteobacteria H Demethylmenaquinone methyltransferase - - - ko:K02553 - - - - ko00000,ko03019 - - - RraA-like SJTD3_k127_3123794_1 639030.JHVA01000001_gene115 2.204e-74 265.0 COG0006@1|root,COG0006@2|Bacteria,3Y3IN@57723|Acidobacteria,2JI8R@204432|Acidobacteriia 2|Bacteria E Creatinase/Prolidase N-terminal domain pepQ - 3.5.3.3 ko:K08688 ko00260,ko00330,ko01100,map00260,map00330,map01100 - R01566 RC00548,RC00549 ko00000,ko00001,ko01000 - - - Creatinase_N,Peptidase_M24 SJTD3_k127_3123794_6 1123508.JH636440_gene1975 1.383e-41 168.0 COG0524@1|root,COG0524@2|Bacteria,2IWUH@203682|Planctomycetes 203682|Planctomycetes G pfkB family carbohydrate kinase - - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB SJTD3_k127_3123794_3 1232453.BAIF02000062_gene1856 3.402e-67 244.0 COG1879@1|root,COG1879@2|Bacteria,1TSBH@1239|Firmicutes,24DCJ@186801|Clostridia 186801|Clostridia G Periplasmic binding protein LacI transcriptional regulator - - - - - - - - - - - - Peripla_BP_4 SJTD3_k127_3123794_7 1232453.BAIF02000062_gene1857 6.925e-34 134.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,26882@186813|unclassified Clostridiales 186801|Clostridia G Part of the ABC transporter complex MglABC involved in galactose methyl galactoside import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_3128803_0 485913.Krac_11064 6.548e-143 471.0 COG3408@1|root,COG3408@2|Bacteria,2G8AA@200795|Chloroflexi 200795|Chloroflexi G Glycogen debranching enzyme N terminal - - - - - - - - - - - - GDE_C,GDE_N SJTD3_k127_3128803_3 1379698.RBG1_1C00001G0843 4.221e-34 140.0 COG1011@1|root,COG1011@2|Bacteria,2NQ1K@2323|unclassified Bacteria 2|Bacteria S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - 3.1.3.5 ko:K07025,ko:K08723 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 SJTD3_k127_3128803_1 66377.JOBH01000007_gene2053 3.428e-49 186.0 COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria 201174|Actinobacteria S Esterase yvaK - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 SJTD3_k127_3128803_2 1382356.JQMP01000003_gene1664 3.013e-38 156.0 COG5309@1|root,COG5309@2|Bacteria,2G8VX@200795|Chloroflexi,27XUZ@189775|Thermomicrobia 189775|Thermomicrobia G Glycosyl hydrolase catalytic core - - - - - - - - - - - - Glyco_hydro_cc SJTD3_k127_3145155_2 485913.Krac_2641 1.202e-115 376.0 COG1233@1|root,COG1233@2|Bacteria,2G60T@200795|Chloroflexi 200795|Chloroflexi Q NAD(P)-binding Rossmann-like domain - - - - - - - - - - - - NAD_binding_8 SJTD3_k127_3145155_5 234267.Acid_6208 2.802e-96 335.0 COG1290@1|root,COG2010@1|root,COG1290@2|Bacteria,COG2010@2|Bacteria,3Y4F0@57723|Acidobacteria 57723|Acidobacteria C Cytochrome b(C-terminal)/b6/petD - - - ko:K00412 ko00190,ko01100,ko02020,ko04260,ko04714,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map02020,map04260,map04714,map04932,map05010,map05012,map05016 M00151,M00152 - - ko00000,ko00001,ko00002,ko03029 - - - Cytochrom_B_C,Cytochrom_C,Cytochrome_B SJTD3_k127_3145155_11 330214.NIDE3890 3.581e-32 134.0 COG0723@1|root,COG0723@2|Bacteria,3J0TT@40117|Nitrospirae 40117|Nitrospirae C Rieske [2Fe-2S] domain - - 1.10.9.1 ko:K02636,ko:K03886 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00151,M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske SJTD3_k127_3145155_4 1211035.CD30_04110 5.104e-97 337.0 29MNG@1|root,308K7@2|Bacteria,1VTU1@1239|Firmicutes,4HTYB@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - SJTD3_k127_3145155_12 1243664.CAVL020000020_gene3210 7.849e-13 75.0 COG3794@1|root,COG3794@2|Bacteria,1U5BN@1239|Firmicutes,4IC0V@91061|Bacilli,1ZKTH@1386|Bacillus 91061|Bacilli C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - - SJTD3_k127_3145155_6 1163617.SCD_n00336 4.314e-92 322.0 COG4585@1|root,COG4585@2|Bacteria,1MZY3@1224|Proteobacteria,2VZ3M@28216|Betaproteobacteria 28216|Betaproteobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 SJTD3_k127_3145155_7 580332.Slit_2500 9.927e-65 228.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria,2VMXI@28216|Betaproteobacteria 28216|Betaproteobacteria K response regulator - - - - - - - - - - - - GerE,Response_reg SJTD3_k127_3145155_8 1120973.AQXL01000103_gene2504 8.252e-45 175.0 COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,4HCSI@91061|Bacilli,278TK@186823|Alicyclobacillaceae 91061|Bacilli K helix_turn_helix isocitrate lyase regulation kipR - - ko:K13641 - - - - ko00000,ko03000 - - - HTH_IclR,IclR SJTD3_k127_3145155_3 1174528.JH992893_gene5998 3.358e-112 369.0 COG1028@1|root,COG1028@2|Bacteria,1G2YY@1117|Cyanobacteria 1117|Cyanobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 SJTD3_k127_3145155_1 981384.AEYW01000001_gene1470 7.302e-116 402.0 COG1879@1|root,COG1879@2|Bacteria,1N64T@1224|Proteobacteria,2UD6Y@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Periplasmic binding protein LacI transcriptional regulator - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_3145155_10 1048834.TC41_2553 7.661e-35 154.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HV49@91061|Bacilli 91061|Bacilli G Periplasmic binding protein domain - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_3145155_0 411684.HPDFL43_01980 8.823e-157 511.0 COG1129@1|root,COG1129@2|Bacteria,1MU22@1224|Proteobacteria,2TQJV@28211|Alphaproteobacteria,43H5X@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_3145155_9 391626.OAN307_c30890 3.699e-36 143.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2U0D6@28211|Alphaproteobacteria 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_3151335_0 485913.Krac_7924 9.982e-75 261.0 COG2318@1|root,COG2318@2|Bacteria,2G8NT@200795|Chloroflexi 200795|Chloroflexi S Mycothiol maleylpyruvate isomerase N-terminal domain - - - - - - - - - - - - MDMPI_N SJTD3_k127_3151335_1 479434.Sthe_3267 4.992e-11 67.0 COG1989@1|root,COG1989@2|Bacteria,2G797@200795|Chloroflexi,27YGY@189775|Thermomicrobia 189775|Thermomicrobia NOU Type IV leader peptidase family - - 3.4.23.43 ko:K02654 - M00331 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - Peptidase_A24 SJTD3_k127_3159454_2 525904.Tter_2870 1.968e-07 55.0 COG0704@1|root,COG0704@2|Bacteria,2NPWX@2323|unclassified Bacteria 2|Bacteria P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU SJTD3_k127_3159454_0 926569.ANT_27750 1.023e-107 357.0 COG1117@1|root,COG1117@2|Bacteria,2G646@200795|Chloroflexi 200795|Chloroflexi P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran SJTD3_k127_3159454_1 926550.CLDAP_00820 5.992e-71 243.0 COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi 200795|Chloroflexi P TIGRFAM phosphate ABC transporter, inner membrane subunit PstA - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 SJTD3_k127_3162006_0 525904.Tter_1001 1.19e-36 145.0 2DM5T@1|root,31U0Y@2|Bacteria,2NRH0@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function (DUF4126) - - - - - - - - - - - - DUF4126 SJTD3_k127_3162006_4 1068980.ARVW01000001_gene306 3.531e-06 59.0 COG1714@1|root,COG1714@2|Bacteria,2HGSH@201174|Actinobacteria,4E35T@85010|Pseudonocardiales 201174|Actinobacteria S RDD family pra GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - - - - - - - - - - RDD SJTD3_k127_3162006_2 1128421.JAGA01000001_gene2411 7.095e-28 125.0 2E3IJ@1|root,32YH0@2|Bacteria,2NS0X@2323|unclassified Bacteria 2|Bacteria S Predicted membrane protein (DUF2085) - - - - - - - - - - - - DUF2085 SJTD3_k127_3162006_1 401526.TcarDRAFT_2084 6.268e-33 132.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4H27H@909932|Negativicutes 909932|Negativicutes H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein SJTD3_k127_3162963_2 1265505.ATUG01000002_gene1740 3.294e-26 115.0 COG0665@1|root,COG0665@2|Bacteria,1MVM6@1224|Proteobacteria,42NTX@68525|delta/epsilon subdivisions,2WMFG@28221|Deltaproteobacteria 28221|Deltaproteobacteria E sarcosine oxidase - - - - - - - - - - - - DAO SJTD3_k127_3162963_1 504472.Slin_2482 4.76e-79 271.0 COG3836@1|root,COG3836@2|Bacteria,4NG3S@976|Bacteroidetes,47NSV@768503|Cytophagia 976|Bacteroidetes G HpcH/HpaI aldolase/citrate lyase family - - 4.1.2.52 ko:K02510 ko00350,ko01120,map00350,map01120 - R01645,R01647 RC00307,RC00572,RC00574,RC03057 ko00000,ko00001,ko01000 - - - HpcH_HpaI SJTD3_k127_3162963_0 1382306.JNIM01000001_gene1290 8.578e-141 452.0 COG0473@1|root,COG0473@2|Bacteria,2G68P@200795|Chloroflexi 200795|Chloroflexi C Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.41 ko:K00030 ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010 R00709 RC00114 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh SJTD3_k127_3167862_2 1521187.JPIM01000020_gene235 2.87e-40 157.0 COG0559@1|root,COG0559@2|Bacteria,2GBUW@200795|Chloroflexi,376UV@32061|Chloroflexia 32061|Chloroflexia E Branched-chain amino acid transport system / permease component - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SJTD3_k127_3167862_1 867845.KI911784_gene3000 1.137e-100 332.0 COG0410@1|root,COG0410@2|Bacteria,2G69M@200795|Chloroflexi,374V9@32061|Chloroflexia 32061|Chloroflexia E PFAM ABC transporter related - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran SJTD3_k127_3167862_0 324602.Caur_3635 3.219e-104 345.0 COG0411@1|root,COG0411@2|Bacteria,2GABI@200795|Chloroflexi,376AR@32061|Chloroflexia 32061|Chloroflexia E PFAM ABC transporter related - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C SJTD3_k127_3167862_3 1521187.JPIM01000020_gene232 6.889e-18 83.0 COG0683@1|root,COG0683@2|Bacteria,2G904@200795|Chloroflexi,3754R@32061|Chloroflexia 32061|Chloroflexia E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 SJTD3_k127_3173463_1 644282.Deba_2127 1.058e-115 383.0 COG1073@1|root,COG1073@2|Bacteria,1QX7X@1224|Proteobacteria,43C0Z@68525|delta/epsilon subdivisions,2X7BK@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Ndr family - - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_3173463_0 1122915.AUGY01000014_gene2769 3.514e-141 459.0 COG4447@1|root,COG4447@2|Bacteria,1UU3Y@1239|Firmicutes,4HCEG@91061|Bacilli 91061|Bacilli S cellulose binding hcf136 - - - - - - - - - - - BNR SJTD3_k127_3173463_3 1122915.AUGY01000014_gene2770 1.151e-25 108.0 COG1977@1|root,COG1977@2|Bacteria 2|Bacteria H Mo-molybdopterin cofactor metabolic process - - - ko:K03636 ko04122,map04122 - - - ko00000,ko00001 - - - ThiS SJTD3_k127_3173463_2 272134.KB731325_gene467 6.044e-43 165.0 COG0708@1|root,COG0708@2|Bacteria 2|Bacteria L double-stranded DNA 3'-5' exodeoxyribonuclease activity - - 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos SJTD3_k127_3175908_6 1382356.JQMP01000003_gene1473 1.16e-17 84.0 COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi,27XN1@189775|Thermomicrobia 189775|Thermomicrobia J DALR anticodon binding domain argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - DALR_1,tRNA-synt_1d SJTD3_k127_3175908_5 240016.ABIZ01000001_gene1535 2.182e-18 94.0 2EHUP@1|root,33BKB@2|Bacteria,46XGF@74201|Verrucomicrobia,2IVUH@203494|Verrucomicrobiae 203494|Verrucomicrobiae - - - - - - - - - - - - - - - SJTD3_k127_3175908_0 511051.CSE_09680 5.605e-213 670.0 COG2403@1|root,COG2403@2|Bacteria 2|Bacteria S cyclic 2,3-diphosphoglycerate synthetase activity cpgS - - ko:K05716 - - R03298 RC00900 ko00000,ko01000 - - - cobW SJTD3_k127_3175908_4 1034345.CAEM01000023_gene786 2.137e-22 103.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CWB2@84998|Coriobacteriia 84998|Coriobacteriia J Belongs to the bacterial ribosomal protein bS16 family rpsP - - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 SJTD3_k127_3175908_7 335541.Swol_1496 8.308e-17 82.0 COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,42K68@68298|Syntrophomonadaceae 186801|Clostridia S Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 SJTD3_k127_3175908_2 401526.TcarDRAFT_2171 4.735e-30 128.0 COG0806@1|root,COG0806@2|Bacteria 2|Bacteria J ribosome binding rimM GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM SJTD3_k127_3175908_1 1449063.JMLS01000026_gene3880 5.944e-53 193.0 arCOG09454@1|root,30G4A@2|Bacteria,1V448@1239|Firmicutes,4HHA0@91061|Bacilli,26XXD@186822|Paenibacillaceae 91061|Bacilli - - - - - - - - - - - - - - - SJTD3_k127_3175908_3 857293.CAAU_0709 5.724e-30 125.0 COG0517@1|root,COG0517@2|Bacteria,1V9ZB@1239|Firmicutes,25ESC@186801|Clostridia,36USA@31979|Clostridiaceae 186801|Clostridia S CBS domain - - - - - - - - - - - - CBS SJTD3_k127_3208168_0 479434.Sthe_1459 4.33e-141 459.0 COG0498@1|root,COG0498@2|Bacteria,2G66Y@200795|Chloroflexi,27XPE@189775|Thermomicrobia 189775|Thermomicrobia E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP SJTD3_k127_3208168_1 485913.Krac_10994 1.773e-76 270.0 COG0083@1|root,COG0083@2|Bacteria,2G6MP@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB - 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N SJTD3_k127_3208994_2 525904.Tter_2540 1.394e-33 136.0 COG2223@1|root,COG2223@2|Bacteria 2|Bacteria P nitrite transmembrane transporter activity - - - - - - - - - - - - - SJTD3_k127_3208994_1 1121085.AUCI01000006_gene1562 3.355e-56 213.0 28IB3@1|root,2Z8DK@2|Bacteria,1UZH8@1239|Firmicutes,4HEHS@91061|Bacilli,1ZBKM@1386|Bacillus 91061|Bacilli - - - - - - - - - - - - - - SLAC1 SJTD3_k127_3208994_0 266117.Rxyl_1204 2.849e-129 424.0 COG2223@1|root,COG2223@2|Bacteria,2GJ1I@201174|Actinobacteria,4CQM5@84995|Rubrobacteria 84995|Rubrobacteria P Major Facilitator Superfamily - - - ko:K02575 ko00910,map00910 M00615 - - ko00000,ko00001,ko00002,ko02000 2.A.1.8 - - MFS_1 SJTD3_k127_3208994_3 177437.HRM2_00860 2.301e-11 69.0 COG0664@1|root,COG0664@2|Bacteria,1NPY0@1224|Proteobacteria,42RCQ@68525|delta/epsilon subdivisions,2WN1Y@28221|Deltaproteobacteria,2MMHJ@213118|Desulfobacterales 28221|Deltaproteobacteria K Crp-like helix-turn-helix domain - - - ko:K21564 - - - - ko00000,ko03000 - - - HTH_Crp_2,cNMP_binding SJTD3_k127_3214430_2 867845.KI911784_gene3289 8.977e-133 435.0 COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria 2|Bacteria P Polysulphide reductase, NrfD ttrC - 1.5.5.1 ko:K00311,ko:K08359 ko00920,ko01120,ko02020,map00920,map01120,map02020 - R10150 RC03109 ko00000,ko00001,ko01000,ko02000 5.A.3.10 - - Fer4_11,Fer4_4,Fer4_8,NrfD SJTD3_k127_3214430_0 326427.Cagg_0511 0.0 1752.0 COG0243@1|root,COG0243@2|Bacteria,2G5ZB@200795|Chloroflexi,37670@32061|Chloroflexia 32061|Chloroflexia C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_3214430_5 383372.Rcas_2174 1.883e-55 208.0 COG3381@1|root,COG3381@2|Bacteria,2G96P@200795|Chloroflexi,377BV@32061|Chloroflexia 32061|Chloroflexia S Nitrate reductase delta subunit - - - - - - - - - - - - Nitrate_red_del SJTD3_k127_3214430_4 498761.HM1_0070 8.52e-67 237.0 COG0730@1|root,COG0730@2|Bacteria,1TPMA@1239|Firmicutes,25CI8@186801|Clostridia 186801|Clostridia S membrane transporter protein - - - ko:K07090 - - - - ko00000 - - - TauE SJTD3_k127_3214430_1 316067.Geob_3303 4.735e-187 595.0 COG0513@1|root,COG0513@2|Bacteria,1MU49@1224|Proteobacteria,42MGZ@68525|delta/epsilon subdivisions,2WIY6@28221|Deltaproteobacteria,43UHV@69541|Desulfuromonadales 28221|Deltaproteobacteria JKL helicase superfamily c-terminal domain rhlE-2 - 3.6.4.13 ko:K11927 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DEAD,Helicase_C SJTD3_k127_3214430_6 1380346.JNIH01000018_gene5407 2.019e-08 59.0 2BUTG@1|root,32Q51@2|Bacteria,2ISEW@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_3214430_3 357808.RoseRS_3373 1.424e-88 304.0 COG3239@1|root,COG3239@2|Bacteria,2G80Y@200795|Chloroflexi 200795|Chloroflexi I PFAM Fatty acid desaturase - - - - - - - - - - - - FA_desaturase SJTD3_k127_3220886_4 926560.KE387027_gene1021 8.197e-93 308.0 2DB7V@1|root,2Z7NX@2|Bacteria,1WM7S@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - SJTD3_k127_3220886_0 1501230.ET33_02970 0.0 1030.0 COG2909@1|root,COG2909@2|Bacteria,1UIMV@1239|Firmicutes,4HD7H@91061|Bacilli,26QDM@186822|Paenibacillaceae 91061|Bacilli K helix_turn_helix, Lux Regulon - - - ko:K03556 - - - - ko00000,ko03000 - - - GerE SJTD3_k127_3220886_7 329726.AM1_6084 4.554e-23 113.0 2DNVA@1|root,32ZBE@2|Bacteria,1GFXX@1117|Cyanobacteria 1117|Cyanobacteria - - - - - - - - - - - - - - - SJTD3_k127_3220886_3 1408254.T458_09100 4.089e-105 356.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli,26QXS@186822|Paenibacillaceae 91061|Bacilli C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 SJTD3_k127_3220886_2 1121272.KB903249_gene2239 1.197e-120 395.0 COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DB8J@85008|Micromonosporales 201174|Actinobacteria C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 SJTD3_k127_3220886_5 298654.FraEuI1c_2597 5.673e-67 234.0 COG0778@1|root,COG0778@2|Bacteria,2I6AB@201174|Actinobacteria 201174|Actinobacteria C PFAM Nitroreductase - - - - - - - - - - - - Nitroreductase SJTD3_k127_3220886_1 479434.Sthe_3486 3.239e-226 723.0 COG4867@1|root,COG4867@2|Bacteria,2G8A6@200795|Chloroflexi,27XPF@189775|Thermomicrobia 189775|Thermomicrobia S von Willebrand factor (vWF) type A domain - - - - - - - - - - - - - SJTD3_k127_3222192_2 335283.Neut_1057 1.433e-50 190.0 COG0500@1|root,COG2226@2|Bacteria,1MW7J@1224|Proteobacteria,2VR1M@28216|Betaproteobacteria 28216|Betaproteobacteria Q O-methyltransferase - - - - - - - - - - - - Dimerisation2,Methyltransf_2 SJTD3_k127_3222192_0 42256.RradSPS_0358 8.826e-163 544.0 COG2909@1|root,COG2909@2|Bacteria,2HENR@201174|Actinobacteria,4CPC9@84995|Rubrobacteria 84995|Rubrobacteria K helix_turn_helix, Lux Regulon - - - ko:K03556 - - - - ko00000,ko03000 - - - AAA_16,AAA_22,GerE SJTD3_k127_3222192_1 1214101.BN159_5889 1.609e-65 233.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - GerE,TPR_12 SJTD3_k127_3241786_0 269797.Mbar_A1683 4.232e-59 211.0 COG0604@1|root,arCOG01458@2157|Archaea,2XURG@28890|Euryarchaeota,2N9N6@224756|Methanomicrobia 224756|Methanomicrobia C Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 SJTD3_k127_3241786_2 797114.C475_17543 0.0003189 51.0 arCOG07632@1|root,arCOG07632@2157|Archaea,2XZ60@28890|Euryarchaeota,23X1M@183963|Halobacteria 183963|Halobacteria S Domain of unknown function (DUF4352) - - - - - - - - - - - - DUF4352 SJTD3_k127_3241786_1 1128421.JAGA01000004_gene2645 4.821e-39 163.0 COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria 2|Bacteria S Glycosyl transferase, family 2 wgeF - - - - - - - - - - - GT87,Glycos_transf_2 SJTD3_k127_3242976_1 485913.Krac_11012 1.766e-76 262.0 COG0243@1|root,COG0243@2|Bacteria,2G62W@200795|Chloroflexi 200795|Chloroflexi C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - 1.17.1.9 ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_3242976_0 485913.Krac_7393 2.513e-84 284.0 COG0437@1|root,COG0437@2|Bacteria,2G6VF@200795|Chloroflexi 200795|Chloroflexi C PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - ko:K00124 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 - R00519 RC02796 ko00000,ko00001 - - - Fer4_11,Fer4_3,Fer4_4,Fer4_7 SJTD3_k127_3248204_1 1034943.BN1094_03219 5.717e-05 55.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,1JD50@118969|Legionellales 118969|Legionellales L Bacterial DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon SJTD3_k127_3248204_0 525368.HMPREF0591_4078 3.848e-47 182.0 COG2114@1|root,COG2114@2|Bacteria,2IC2V@201174|Actinobacteria,237XA@1762|Mycobacteriaceae 201174|Actinobacteria T guanylate cyclase catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_cyc SJTD3_k127_326218_0 684949.ATTJ01000002_gene234 3.121e-67 236.0 COG1541@1|root,COG1541@2|Bacteria,1WM4P@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - - - - - - - - - - - SJTD3_k127_326218_1 869210.Marky_1035 1.678e-29 126.0 COG0785@1|root,COG0785@2|Bacteria,1WIZH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O PFAM cytochrome c biogenesis protein, transmembrane region - - - - - - - - - - - - DsbD SJTD3_k127_326218_2 1408303.JNJJ01000078_gene1188 1.996e-08 57.0 COG4263@1|root,COG4263@2|Bacteria 2|Bacteria C nitrous-oxide reductase activity - - - - - - - - - - - - Cupredoxin_1 SJTD3_k127_3271415_2 357808.RoseRS_1536 1.841e-31 137.0 COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia 32061|Chloroflexia D Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 SJTD3_k127_3271415_3 1449058.JQKT01000007_gene385 4.623e-30 123.0 COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria,4FNUN@85023|Microbacteriaceae 201174|Actinobacteria S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA SJTD3_k127_3271415_0 1120973.AQXL01000132_gene2249 3.14e-150 486.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,27869@186823|Alicyclobacillaceae 91061|Bacilli I Thiolase, C-terminal domain mmgA GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177 RC00004,RC00326 ko00000,ko00001,ko00002,ko01000,ko04147 - - iYO844.BSU24170 Thiolase_C,Thiolase_N SJTD3_k127_3271415_1 309801.trd_0039 2.557e-100 331.0 COG1960@1|root,COG1960@2|Bacteria,2G65J@200795|Chloroflexi,27Y45@189775|Thermomicrobia 189775|Thermomicrobia C Acyl- CoA dehydrogenase type 2 domain - - - - - - - - - - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SJTD3_k127_3273109_1 1048983.EL17_06300 1.371e-204 642.0 COG1523@1|root,COG1523@2|Bacteria,4NIH2@976|Bacteroidetes,47KIY@768503|Cytophagia 976|Bacteroidetes G Belongs to the glycosyl hydrolase 13 family glgX - 3.2.1.41,3.2.1.68 ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02111,R09995,R11261 - ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48 SJTD3_k127_3273109_0 1128421.JAGA01000001_gene2003 4.462e-205 655.0 COG0296@1|root,COG0296@2|Bacteria 2|Bacteria G 1,4-alpha-glucan branching enzyme activity treZ - 3.2.1.141 ko:K01236 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R09995,R11256 RC00049 ko00000,ko00001,ko00002,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,DUF3459 SJTD3_k127_3273109_2 485913.Krac_9000 4.221e-188 596.0 COG0148@1|root,COG0148@2|Bacteria,2G5VB@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno - 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N SJTD3_k127_3294108_0 485913.Krac_9033 1.927e-209 669.0 COG0664@1|root,COG0664@2|Bacteria,2G63K@200795|Chloroflexi 200795|Chloroflexi T - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - - - - - - - - - - - SJTD3_k127_3294108_1 765420.OSCT_0965 2.229e-56 221.0 28M0D@1|root,2ZAFE@2|Bacteria,2G9HQ@200795|Chloroflexi 200795|Chloroflexi S Putative ATP-binding cassette - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran_2 SJTD3_k127_3294108_2 765420.OSCT_0964 1.919e-46 170.0 COG1131@1|root,COG1131@2|Bacteria,2G6KA@200795|Chloroflexi 200795|Chloroflexi V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_3294568_0 1128421.JAGA01000002_gene634 5.149e-158 507.0 COG3185@1|root,COG3185@2|Bacteria 2|Bacteria E 4-Hydroxyphenylpyruvate dioxygenase hpd GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.27,1.13.11.46 ko:K00457,ko:K16421 ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130 M00044 R01372,R02521,R06632 RC00505,RC00738,RC01471 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Glyoxalase,Glyoxalase_5 SJTD3_k127_3294568_1 485913.Krac_3644 6.876e-95 321.0 COG0179@1|root,COG0179@2|Bacteria,2G7MW@200795|Chloroflexi 200795|Chloroflexi Q PFAM fumarylacetoacetate (FAA) hydrolase - - 3.7.1.2 ko:K16171 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R01364 RC00326,RC00446 ko00000,ko00001,ko00002,ko01000 - - - FAA_hydrolase SJTD3_k127_3294568_4 221288.JH992901_gene5628 5.096e-16 81.0 COG1598@1|root,COG1598@2|Bacteria,1G978@1117|Cyanobacteria 1117|Cyanobacteria S PFAM Uncharacterised protein family UPF0150 - - - - - - - - - - - - - SJTD3_k127_3294568_2 316274.Haur_2762 2.093e-82 280.0 COG3508@1|root,COG3508@2|Bacteria,2G7RN@200795|Chloroflexi,3766I@32061|Chloroflexia 32061|Chloroflexia Q PFAM homogentisate 12-dioxygenase - - 1.13.11.5 ko:K00451 ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120 M00044 R02519 RC00737 ko00000,ko00001,ko00002,ko01000 - - - HgmA SJTD3_k127_3296559_1 926554.KI912628_gene2716 6.401e-62 218.0 COG3467@1|root,COG3467@2|Bacteria 2|Bacteria T pyridoxamine 5'-phosphate - - - ko:K07005 - - - - ko00000 - - - Pyridox_ox_2 SJTD3_k127_3296559_2 575590.HMPREF0156_01407 3.592e-20 93.0 COG1308@1|root,COG1308@2|Bacteria,4NVAE@976|Bacteroidetes 976|Bacteroidetes K Domain of unknown function (DUF4342) - - - - - - - - - - - - DUF4342 SJTD3_k127_3296559_0 926569.ANT_13380 1.131e-79 274.0 COG1085@1|root,COG1085@2|Bacteria,2G6K5@200795|Chloroflexi 200795|Chloroflexi H TIGRFAM galactose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf SJTD3_k127_3302704_0 1095769.CAHF01000006_gene1856 2.255e-63 225.0 COG5637@1|root,COG5637@2|Bacteria,1RCEX@1224|Proteobacteria,2VQP4@28216|Betaproteobacteria,4771P@75682|Oxalobacteraceae 28216|Betaproteobacteria O Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc SJTD3_k127_3323882_1 1122951.ATUE01000007_gene800 2.082e-23 100.0 COG1670@1|root,COG1670@2|Bacteria,1N9F9@1224|Proteobacteria,1SCFK@1236|Gammaproteobacteria,3NPCG@468|Moraxellaceae 1236|Gammaproteobacteria J Protein of unknown function (DUF3565) - - - - - - - - - - - - DUF3565 SJTD3_k127_3323882_2 329726.AM1_1201 3.811e-10 71.0 2BR4H@1|root,32K2F@2|Bacteria,1GGVQ@1117|Cyanobacteria 1117|Cyanobacteria S Domain of unknown function (DUF4259) - - - - - - - - - - - - DUF4259 SJTD3_k127_3323882_0 1144275.COCOR_03926 3.711e-69 247.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi SJTD3_k127_3327152_2 404589.Anae109_2250 1.009e-42 163.0 COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42PVA@68525|delta/epsilon subdivisions,2WJ10@28221|Deltaproteobacteria 28221|Deltaproteobacteria P transporter of a GTP-driven Fe(2 ) uptake system feoB-1 - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - - FeoB_C,FeoB_N,Gate SJTD3_k127_3327152_0 1123023.JIAI01000001_gene6862 1.512e-105 352.0 COG0596@1|root,COG0596@2|Bacteria,2GJCT@201174|Actinobacteria,4E17M@85010|Pseudonocardiales 201174|Actinobacteria S Alpha/beta hydrolase family - - 3.8.1.3 ko:K01561 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - Abhydrolase_1 SJTD3_k127_3327152_1 696281.Desru_1400 2.965e-48 183.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - 3.5.1.106 ko:K15357 ko00760,ko01120,map00760,map01120 M00622 R09126 RC00323,RC02431 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_3,Abhydrolase_6,Hydrolase_4 SJTD3_k127_3327152_3 1120953.AUBH01000002_gene1438 1.836e-11 68.0 COG1814@1|root,COG1814@2|Bacteria,1RBDP@1224|Proteobacteria,1T04K@1236|Gammaproteobacteria 1236|Gammaproteobacteria S VIT family - - - - - - - - - - - - VIT1 SJTD3_k127_3346229_0 1121377.KB906436_gene921 3.617e-160 527.0 COG2909@1|root,COG2909@2|Bacteria 2|Bacteria K trisaccharide binding - - - - - - - - - - - - AAA_16,GerE SJTD3_k127_3346229_1 316274.Haur_1480 1.254e-49 182.0 COG0738@1|root,COG0738@2|Bacteria,2G70U@200795|Chloroflexi,376XB@32061|Chloroflexia 32061|Chloroflexia G PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1 SJTD3_k127_3353608_4 485913.Krac_7491 3.855e-13 73.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 SJTD3_k127_3353608_5 251221.35211275 6.13e-10 66.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - - - - - - - - - - - Glyoxalase SJTD3_k127_3353608_1 1487953.JMKF01000069_gene95 2.422e-52 196.0 COG0122@1|root,COG0122@2|Bacteria,1G394@1117|Cyanobacteria,1HAMC@1150|Oscillatoriales 1117|Cyanobacteria L endonuclease III - - 3.2.2.21 ko:K01247 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD SJTD3_k127_3353608_0 1128421.JAGA01000002_gene1835 7.331e-54 198.0 COG0639@1|root,COG0639@2|Bacteria,2NPHT@2323|unclassified Bacteria 2|Bacteria T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 SJTD3_k127_3353608_3 595460.RRSWK_02306 1.675e-22 99.0 COG4859@1|root,COG4859@2|Bacteria,2J4F1@203682|Planctomycetes 203682|Planctomycetes S Psort location Cytoplasmic, score - - - - - - - - - - - - - SJTD3_k127_3353608_6 334413.FMG_0548 6.82e-05 47.0 COG0695@1|root,COG0695@2|Bacteria,1VI6J@1239|Firmicutes,24QNT@186801|Clostridia,22HZ2@1570339|Peptoniphilaceae 186801|Clostridia O Glutaredoxin - - - - - - - - - - - - Glutaredoxin SJTD3_k127_3353608_2 645991.Sgly_2736 4.38e-37 144.0 COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes 1239|Firmicutes S Acetyltransferase involved in intracellular survival and related - - - - - - - - - - - - Acetyltransf_9,SCP2_2 SJTD3_k127_3357906_1 926550.CLDAP_25810 4.56e-104 345.0 COG0674@1|root,COG0674@2|Bacteria,2G5UG@200795|Chloroflexi 200795|Chloroflexi C Pyruvate:ferredoxin oxidoreductase core domain II - - 1.2.7.11,1.2.7.3 ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFOR_II,POR_N SJTD3_k127_3357906_0 926569.ANT_04510 6.777e-115 377.0 COG1013@1|root,COG1013@2|Bacteria,2G5VG@200795|Chloroflexi 200795|Chloroflexi C Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C SJTD3_k127_3357906_2 926569.ANT_04520 8.522e-52 197.0 COG1014@1|root,COG1014@2|Bacteria,2G6FV@200795|Chloroflexi 200795|Chloroflexi C Pyruvate ferredoxin/flavodoxin oxidoreductase porG - 1.2.7.1,1.2.7.3 ko:K00172,ko:K00177 ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00307,M00374,M00620 R01196,R01197,R01199,R08034 RC00004,RC00250,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - POR SJTD3_k127_3357906_3 644283.Micau_4753 8.354e-05 49.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria,4DCDB@85008|Micromonosporales 201174|Actinobacteria S Belongs to the peptidase M50B family - - - - - - - - - - - - CBS,Peptidase_M50 SJTD3_k127_3361855_0 383372.Rcas_2309 3.588e-110 360.0 COG1013@1|root,COG1013@2|Bacteria,2G679@200795|Chloroflexi,374ZH@32061|Chloroflexia 32061|Chloroflexia C PFAM thiamine pyrophosphate protein domain protein TPP-binding - - 1.2.7.11,1.2.7.3 ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00009,M00011,M00173,M00620 R01196,R01197 RC00004,RC02742,RC02833 br01601,ko00000,ko00001,ko00002,ko01000 - - - PFO_beta_C,TPP_enzyme_C SJTD3_k127_3361855_2 555079.Toce_0696 2.41e-12 72.0 COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,42EM7@68295|Thermoanaerobacterales 186801|Clostridia C NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding hymB - 1.12.1.3,1.17.1.11,1.6.5.3 ko:K00335,ko:K18331,ko:K22339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB SJTD3_k127_3361855_1 316274.Haur_2376 5.186e-18 88.0 2EM6G@1|root,33EVQ@2|Bacteria,2G9RV@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - SJTD3_k127_3361855_3 1173025.GEI7407_1503 2.869e-11 76.0 COG2203@1|root,COG5002@1|root,COG2203@2|Bacteria,COG5002@2|Bacteria,1GPXH@1117|Cyanobacteria 1117|Cyanobacteria T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ETR1 - - - - - - - - - - - CBS,GAF,GAF_3,HATPase_c,HisKA,HisKA_2,PAS,PAS_3,PAS_4,PAS_8,PAS_9 SJTD3_k127_3365693_7 1347342.BN863_33480 6.06e-05 52.0 COG1629@1|root,COG4771@2|Bacteria,4NEIG@976|Bacteroidetes,1HXSZ@117743|Flavobacteriia 976|Bacteroidetes P TonB-dependent receptor - - - - - - - - - - - - CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug SJTD3_k127_3365693_2 370438.PTH_1852 2.25e-34 140.0 COG3856@1|root,COG3856@2|Bacteria,1VA6N@1239|Firmicutes,24N58@186801|Clostridia,2628B@186807|Peptococcaceae 186801|Clostridia S Protein of unknown function (DUF1290) sbp - - - - - - - - - - - DUF1290 SJTD3_k127_3365693_5 316274.Haur_3505 2.532e-15 88.0 COG1589@1|root,COG1589@2|Bacteria,2G7FV@200795|Chloroflexi,375TM@32061|Chloroflexia 32061|Chloroflexia D Cell division protein FtsQ ftsQ - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 SJTD3_k127_3365693_0 479434.Sthe_1990 8.241e-137 445.0 COG1181@1|root,COG1181@2|Bacteria,2G5RS@200795|Chloroflexi,27XTQ@189775|Thermomicrobia 189775|Thermomicrobia F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N SJTD3_k127_3365693_6 1123368.AUIS01000006_gene561 7.891e-15 81.0 COG3861@1|root,COG3861@2|Bacteria,1NHME@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF2382) - - - - - - - - - - - - DUF2382 SJTD3_k127_3365693_3 1500894.JQNN01000001_gene2181 2.097e-21 106.0 COG3861@1|root,COG3861@2|Bacteria,1RJWQ@1224|Proteobacteria,2VTBN@28216|Betaproteobacteria,4752I@75682|Oxalobacteraceae 28216|Betaproteobacteria S Domain of unknown function (DUF2382) - - - - - - - - - - - - DUF2382 SJTD3_k127_3365693_4 42256.RradSPS_0677 1.244e-16 93.0 28JXC@1|root,2Z9MV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DisA_N SJTD3_k127_3365693_1 926569.ANT_23420 2.441e-60 219.0 COG0812@1|root,COG0812@2|Bacteria,2G6H3@200795|Chloroflexi 200795|Chloroflexi M Cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C SJTD3_k127_3375169_0 316274.Haur_4664 1.053e-81 291.0 COG0642@1|root,COG2205@2|Bacteria,2GBIY@200795|Chloroflexi 200795|Chloroflexi T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA SJTD3_k127_3375169_1 316274.Haur_4663 1.103e-81 282.0 COG0745@1|root,COG0745@2|Bacteria,2GAPE@200795|Chloroflexi,375I7@32061|Chloroflexia 32061|Chloroflexia K Two component transcriptional regulator, winged helix family - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SJTD3_k127_3400222_1 1521187.JPIM01000086_gene733 2.924e-43 173.0 COG2730@1|root,COG2730@2|Bacteria 2|Bacteria G polysaccharide catabolic process - - - - - - - - - - - - Cellulase SJTD3_k127_3400222_2 1382356.JQMP01000003_gene1396 1.263e-39 169.0 COG2373@1|root,COG3591@1|root,COG2373@2|Bacteria,COG3591@2|Bacteria 2|Bacteria E Belongs to the peptidase S1B family - - - ko:K13735 ko05100,map05100 - - - ko00000,ko00001 - - - Big_1,DUF3494,IAT_beta,Invasin_D3 SJTD3_k127_3400222_0 573061.Clocel_2567 1.851e-85 310.0 COG2755@1|root,COG2755@2|Bacteria,1V72M@1239|Firmicutes,24MBI@186801|Clostridia 186801|Clostridia E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - CBM_35,Dockerin_1,Glyco_hydro_26,Lipase_GDSL_2 SJTD3_k127_3427069_3 526225.Gobs_2204 2.885e-77 274.0 COG0438@1|root,COG0438@2|Bacteria,2HEWB@201174|Actinobacteria,4EWDA@85013|Frankiales 201174|Actinobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4 SJTD3_k127_3427069_1 1220582.RRU01S_07_01360 1.749e-114 377.0 COG0438@1|root,COG0673@1|root,COG1063@1|root,COG0438@2|Bacteria,COG0673@2|Bacteria,COG1063@2|Bacteria,1RHFK@1224|Proteobacteria,2UAWV@28211|Alphaproteobacteria,4B8I4@82115|Rhizobiaceae 28211|Alphaproteobacteria EM Putative oxidoreductase C terminal - - - - - - - - - - - - ADH_zinc_N,GFO_IDH_MocA,GFO_IDH_MocA_C,Glyco_transf_4,Glycos_transf_1,ox_reductase_C SJTD3_k127_3427069_4 1382306.JNIM01000001_gene1028 6.042e-74 261.0 COG2141@1|root,COG2141@2|Bacteria 2|Bacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase SJTD3_k127_3427069_0 366394.Smed_5687 5.85e-148 476.0 COG0438@1|root,COG2723@1|root,COG0438@2|Bacteria,COG2723@2|Bacteria,1MWU7@1224|Proteobacteria,2TUXP@28211|Alphaproteobacteria,4BAAA@82115|Rhizobiaceae 28211|Alphaproteobacteria GM Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_hydro_42,Glycos_transf_1 SJTD3_k127_3427069_2 452637.Oter_3624 4.655e-94 327.0 COG2723@1|root,COG2723@2|Bacteria 2|Bacteria G beta-glucosidase activity - - - - - - - - - - - - Glyco_hydro_1,Glycos_transf_1 SJTD3_k127_3427069_5 1501230.ET33_36190 8.58e-06 54.0 COG0760@1|root,COG0760@2|Bacteria,1V6TT@1239|Firmicutes,4HJFR@91061|Bacilli,26TZT@186822|Paenibacillaceae 91061|Bacilli O PPIC-type PPIASE domain prsA1 - 5.2.1.8 ko:K03769,ko:K07533 - - - - ko00000,ko01000,ko03110 - - - Cu_amine_oxidN1,Rotamase_3,SurA_N_3 SJTD3_k127_3427585_2 1521187.JPIM01000002_gene3133 3.396e-43 172.0 COG3429@1|root,COG3429@2|Bacteria,2G6ZV@200795|Chloroflexi,375YF@32061|Chloroflexia 32061|Chloroflexia G Glucose-6-phosphate dehydrogenase subunit - - - - - - - - - - - - OpcA_G6PD_assem SJTD3_k127_3427585_0 383372.Rcas_1852 5.594e-206 653.0 COG0364@1|root,COG0364@2|Bacteria,2G5MB@200795|Chloroflexi,374UD@32061|Chloroflexia 32061|Chloroflexia G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone zwf - 1.1.1.363,1.1.1.49 ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 M00004,M00006,M00008 R00835,R02736,R10907 RC00001,RC00066 ko00000,ko00001,ko00002,ko01000,ko04147 - - - G6PD_C,G6PD_N SJTD3_k127_3427585_1 479434.Sthe_2435 1.247e-86 295.0 COG1023@1|root,COG1023@2|Bacteria,2G5YD@200795|Chloroflexi,27XH5@189775|Thermomicrobia 189775|Thermomicrobia C 6-phosphogluconate dehydrogenase, C-terminal domain - - 1.1.1.343,1.1.1.44 ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 M00004,M00006 R01528,R10221 RC00001,RC00539 ko00000,ko00001,ko00002,ko01000 - - - 6PGD,NAD_binding_2 SJTD3_k127_3432503_3 446466.Cfla_3146 2.63e-05 52.0 COG0575@1|root,COG0575@2|Bacteria,2I9PE@201174|Actinobacteria 201174|Actinobacteria I Cytidylyltransferase family cdsA_1 - 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_1 SJTD3_k127_3432503_2 1524467.IV04_13700 1.032e-21 104.0 COG0558@1|root,COG0558@2|Bacteria,1RE0I@1224|Proteobacteria,1S2UQ@1236|Gammaproteobacteria,402GQ@613|Serratia 1236|Gammaproteobacteria I CDP-alcohol phosphatidyltransferase ynbA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - - CDP-OH_P_transf SJTD3_k127_3432503_1 1120950.KB892707_gene4921 4.697e-44 169.0 COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4DPFR@85009|Propionibacteriales 201174|Actinobacteria I Phosphate acyltransferases - - 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase SJTD3_k127_3432503_0 1380393.JHVP01000003_gene1264 2.692e-46 169.0 2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria,4ESE6@85013|Frankiales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_3443485_2 525904.Tter_0616 1.394e-15 83.0 arCOG09854@1|root,3325R@2|Bacteria,2NRU9@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_3443485_0 671143.DAMO_0021 3.52e-62 234.0 COG3055@1|root,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria 2|Bacteria G Galactose oxidase, central domain - - - - - - - - - - - - Kelch_1,Kelch_4,Kelch_6 SJTD3_k127_3443485_1 765420.OSCT_0917 2.509e-34 150.0 COG1874@1|root,COG1874@2|Bacteria,2GBMG@200795|Chloroflexi,376H5@32061|Chloroflexia 32061|Chloroflexia G Flagellar filament outer layer protein Flaa - - - - - - - - - - - - Glyco_hydro_42,Glyco_hydro_cc SJTD3_k127_3443485_3 693977.Deipr_0609 2.514e-05 51.0 COG0180@1|root,COG0180@2|Bacteria 2|Bacteria J Tryptophanyl-tRNA synthetase trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b SJTD3_k127_3469956_0 525904.Tter_0065 3.822e-223 699.0 COG0056@1|root,COG0056@2|Bacteria,2NP0S@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iIT341.HP1134,iSB619.SA_RS10975,iSbBS512_1146.SbBS512_E4187 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N SJTD3_k127_3469956_2 525904.Tter_0066 3.17e-36 143.0 COG0712@1|root,COG0712@2|Bacteria,2NPV0@2323|unclassified Bacteria 2|Bacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B,OSCP SJTD3_k127_3469956_4 255470.cbdbA534 2.554e-16 85.0 COG0711@1|root,COG0711@2|Bacteria,2G76T@200795|Chloroflexi,34CVK@301297|Dehalococcoidia 301297|Dehalococcoidia C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_B SJTD3_k127_3469956_3 309801.trd_1233 1.865e-17 85.0 COG0636@1|root,COG0636@2|Bacteria,2G72D@200795|Chloroflexi,27YPV@189775|Thermomicrobia 189775|Thermomicrobia C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE - - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C SJTD3_k127_3469956_1 309801.trd_1234 9.927e-59 216.0 COG0356@1|root,COG0356@2|Bacteria,2G6NF@200795|Chloroflexi,27XY1@189775|Thermomicrobia 189775|Thermomicrobia C it plays a direct role in the translocation of protons across the membrane atpB - - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A SJTD3_k127_3469956_5 264732.Moth_2386 3.438e-05 51.0 COG5336@1|root,COG5336@2|Bacteria 2|Bacteria C function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex atpI - - ko:K02116 - - - - ko00000,ko00194 3.A.2.1 - - ATPase_gene1 SJTD3_k127_3474242_0 309801.trd_0178 4.022e-50 191.0 COG0483@1|root,COG0483@2|Bacteria,2G6JD@200795|Chloroflexi,27Y5G@189775|Thermomicrobia 189775|Thermomicrobia G Inositol monophosphatase family - - 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P SJTD3_k127_3474242_1 408672.NBCG_01547 8.531e-07 61.0 2DPU0@1|root,333DA@2|Bacteria,2GUNZ@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - LppX_LprAFG SJTD3_k127_3487604_0 1146883.BLASA_1368 5.773e-179 583.0 COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria 201174|Actinobacteria P Heavy metal translocating P-type atpase - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K12954,ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3,3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase SJTD3_k127_3487604_2 1382306.JNIM01000001_gene1433 8.018e-09 62.0 COG2608@1|root,COG2608@2|Bacteria 2|Bacteria P mercury ion transmembrane transporter activity - - 3.6.3.4,3.6.3.54 ko:K01533,ko:K07213,ko:K08364,ko:K17686 ko01524,ko04016,ko04978,map01524,map04016,map04978 - R00086 RC00002 ko00000,ko00001,ko01000,ko02000 1.A.72.1,3.A.3.5 - - HMA,MerT SJTD3_k127_3487604_1 926550.CLDAP_31050 4.991e-118 385.0 COG1488@1|root,COG1488@2|Bacteria,2G70D@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - - SJTD3_k127_3501439_0 485913.Krac_8409 1.747e-123 417.0 COG0493@1|root,COG0493@2|Bacteria 2|Bacteria C 'glutamate synthase - - - - - - - - - - - - Fer4,Fer4_20,Pyr_redox_2 SJTD3_k127_3501439_1 1382356.JQMP01000003_gene1805 2.15e-35 143.0 COG0491@1|root,COG0491@2|Bacteria,2G6X9@200795|Chloroflexi,27YDW@189775|Thermomicrobia 189775|Thermomicrobia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SJTD3_k127_3501439_3 1397278.AYMV01000058_gene1700 1.097e-05 56.0 COG0662@1|root,COG1396@1|root,COG0662@2|Bacteria,COG1396@2|Bacteria,2GN2U@201174|Actinobacteria,4FQCM@85023|Microbacteriaceae 201174|Actinobacteria K Cupin domain - - - - - - - - - - - - Cupin_2,HTH_3,HTH_31 SJTD3_k127_3501439_2 1273538.G159_16340 2.669e-26 122.0 COG0726@1|root,COG1404@1|root,COG0726@2|Bacteria,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HB7D@91061|Bacilli,26F0S@186818|Planococcaceae 91061|Bacilli M Belongs to the peptidase S8 family - - - ko:K13274,ko:K20276 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - FlgD_ig,PPC,Peptidase_S8,SLH SJTD3_k127_3512414_4 1382356.JQMP01000004_gene42 4.942e-23 113.0 2EJ8J@1|root,33CZR@2|Bacteria,2G7F1@200795|Chloroflexi 200795|Chloroflexi S sptr d1c427 - - - - - - - - - - - - - SJTD3_k127_3512414_0 383372.Rcas_1080 1.019e-135 444.0 COG2189@1|root,COG2189@2|Bacteria,2G5WR@200795|Chloroflexi,376Z9@32061|Chloroflexia 32061|Chloroflexia H PFAM DNA methylase N-4 N-6 domain protein - - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase SJTD3_k127_3512414_3 1382359.JIAL01000001_gene881 9.926e-31 126.0 COG0816@1|root,COG0816@2|Bacteria,3Y5AU@57723|Acidobacteria,2JJX3@204432|Acidobacteriia 204432|Acidobacteriia L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA - - - ko:K07447 - - - - ko00000,ko01000 - - - RuvX SJTD3_k127_3512414_1 485913.Krac_5179 5.834e-135 438.0 COG2355@1|root,COG2355@2|Bacteria,2G5Y0@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M19 renal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 SJTD3_k127_3512414_2 1041139.KB902646_gene3375 2.52e-36 142.0 2EBN3@1|root,335NA@2|Bacteria,1PS1W@1224|Proteobacteria,2V490@28211|Alphaproteobacteria,4BFSU@82115|Rhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 SJTD3_k127_3533084_2 1379270.AUXF01000001_gene2235 7.121e-22 100.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE,Response_reg,TPR_19 SJTD3_k127_3533084_3 765420.OSCT_2237 2.142e-10 63.0 COG3153@1|root,COG3153@2|Bacteria 2|Bacteria S transferase activity, transferring acyl groups - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_3533084_1 43989.cce_3762 5.421e-65 232.0 COG0500@1|root,COG2226@2|Bacteria,1G4ZW@1117|Cyanobacteria,3KJWU@43988|Cyanothece 1117|Cyanobacteria Q Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11,Methyltransf_31 SJTD3_k127_3533084_0 1121428.DESHY_110052___1 2.454e-219 705.0 COG1615@1|root,COG1615@2|Bacteria,1TQHM@1239|Firmicutes,248PM@186801|Clostridia,260EY@186807|Peptococcaceae 186801|Clostridia S PFAM Uncharacterised protein family UPF0182 - - - ko:K09118 - - - - ko00000 - - - UPF0182 SJTD3_k127_353996_1 485913.Krac_5343 2e-50 184.0 COG2141@1|root,COG2141@2|Bacteria,2G8PY@200795|Chloroflexi 200795|Chloroflexi C COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_353996_0 35754.JNYJ01000019_gene80 4.556e-119 413.0 COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales 201174|Actinobacteria KT Transcriptional regulator - - - - - - - - - - - - AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12 SJTD3_k127_3599458_0 383372.Rcas_4273 1.138e-155 505.0 COG1070@1|root,COG1070@2|Bacteria,2G5KJ@200795|Chloroflexi 200795|Chloroflexi G carbohydrate kinase FGGY - - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N SJTD3_k127_361325_0 765420.OSCT_0175 3.793e-77 274.0 COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi,3751M@32061|Chloroflexia 32061|Chloroflexia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L SJTD3_k127_361325_2 1128421.JAGA01000002_gene1115 1.453e-61 236.0 COG5617@1|root,COG5617@2|Bacteria 2|Bacteria M Psort location CytoplasmicMembrane, score - - - - - - - - - - - - PMT_2,PTPS_related SJTD3_k127_361325_6 8081.XP_008434739.1 3.395e-10 73.0 COG0457@1|root,KOG1124@2759|Eukaryota,38CY4@33154|Opisthokonta,3BDZ9@33208|Metazoa,3CW1H@33213|Bilateria,483Z1@7711|Chordata,48YBZ@7742|Vertebrata,49TUG@7898|Actinopterygii 33208|Metazoa S Transmembrane and tetratricopeptide repeat containing 2 TMTC2 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0008150,GO:0012505,GO:0016020,GO:0031984,GO:0042175,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048878,GO:0050801,GO:0055065,GO:0055074,GO:0055080,GO:0065007,GO:0065008,GO:0072507,GO:0098771,GO:0098827 - - - - - - - - - - DUF1736,TPR_1,TPR_16,TPR_2,TPR_8 SJTD3_k127_361325_3 1499967.BAYZ01000017_gene6259 4.837e-60 217.0 COG1215@1|root,COG1215@2|Bacteria,2NPW4@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_361325_4 635013.TherJR_2875 8.424e-33 142.0 COG2327@1|root,COG2327@2|Bacteria,1TPTI@1239|Firmicutes,248QN@186801|Clostridia,2603G@186807|Peptococcaceae 186801|Clostridia S PFAM Polysaccharide pyruvyl transferase csaB - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,PS_pyruv_trans SJTD3_k127_361325_1 247634.GPB2148_2212 7.575e-62 228.0 COG0438@1|root,COG0438@2|Bacteria,1MZH2@1224|Proteobacteria,1S9AM@1236|Gammaproteobacteria,1JB0Z@118884|unclassified Gammaproteobacteria 1236|Gammaproteobacteria H Glycosyl transferase, group 1 - - 2.4.1.346 ko:K13668 - - R11703,R11704 - ko00000,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_361325_5 1382306.JNIM01000001_gene958 4.83e-25 116.0 COG0392@1|root,COG0392@2|Bacteria,2G96U@200795|Chloroflexi 200795|Chloroflexi S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SJTD3_k127_361325_7 1206739.BAGJ01000015_gene5219 9.226e-07 53.0 COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4FW2B@85025|Nocardiaceae 201174|Actinobacteria E Peptidase family M1 domain - - - - - - - - - - - - Peptidase_M1 SJTD3_k127_3639378_2 1121422.AUMW01000006_gene699 2.698e-38 147.0 COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,24HX6@186801|Clostridia,261GD@186807|Peptococcaceae 186801|Clostridia S PFAM SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc SJTD3_k127_3639378_4 1131462.DCF50_p1030 6.436e-24 116.0 COG0616@1|root,COG0616@2|Bacteria,1U2Z9@1239|Firmicutes,24DAF@186801|Clostridia,26169@186807|Peptococcaceae 186801|Clostridia OU ClpP class periplasmic serine protease - - - - - - - - - - - - SDH_sah SJTD3_k127_3639378_1 479434.Sthe_0893 4.321e-64 226.0 COG2178@1|root,COG2178@2|Bacteria,2G6RW@200795|Chloroflexi,27Y62@189775|Thermomicrobia 189775|Thermomicrobia J PFAM Translin - - - ko:K07477 - - - - ko00000 - - - - SJTD3_k127_3639378_6 383372.Rcas_1817 1.07e-11 69.0 2EI16@1|root,33BSP@2|Bacteria,2G9M5@200795|Chloroflexi,3761S@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_3639378_0 767817.Desgi_1275 3.455e-66 241.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,247ST@186801|Clostridia,261I8@186807|Peptococcaceae 186801|Clostridia S DegV family - - - - - - - - - - - - DegV SJTD3_k127_3639378_5 525904.Tter_1005 1.487e-21 103.0 COG2823@1|root,COG2823@2|Bacteria 2|Bacteria S hyperosmotic response osmY - - - - - - - - - - - BON SJTD3_k127_3639378_3 1382356.JQMP01000004_gene101 4.786e-36 151.0 COG0613@1|root,COG0613@2|Bacteria,2G71S@200795|Chloroflexi,27XQC@189775|Thermomicrobia 189775|Thermomicrobia S DNA polymerase alpha chain like domain - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - - SJTD3_k127_3643532_2 1128421.JAGA01000002_gene1526 4.387e-26 114.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_12,Methyltransf_25 SJTD3_k127_3643532_0 686340.Metal_0320 1.08e-113 377.0 COG0399@1|root,COG0399@2|Bacteria,1MUPN@1224|Proteobacteria,1RMCS@1236|Gammaproteobacteria,1XDT2@135618|Methylococcales 135618|Methylococcales E Belongs to the DegT DnrJ EryC1 family - - - - - - - - - - - - DegT_DnrJ_EryC1 SJTD3_k127_3643532_1 383372.Rcas_0202 4.016e-98 329.0 COG1216@1|root,COG1216@2|Bacteria,2GBIQ@200795|Chloroflexi,374ZU@32061|Chloroflexia 32061|Chloroflexia S PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_3643532_3 926550.CLDAP_34880 1.812e-14 85.0 COG3103@1|root,COG4991@2|Bacteria 2|Bacteria T sh3 domain protein MA20_15015 - - - - - - - - - - - DUF1236,SH3_3 SJTD3_k127_3646071_1 357808.RoseRS_3332 4.496e-101 341.0 COG0438@1|root,COG0438@2|Bacteria,2G5N9@200795|Chloroflexi,3755Z@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_3646071_2 479433.Caci_7062 1.455e-68 239.0 COG2258@1|root,COG2258@2|Bacteria 2|Bacteria C MOSC domain - - - - - - - - - - - - MOSC SJTD3_k127_3646071_0 935948.KE386495_gene1264 6.2e-108 357.0 COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia,42JEP@68295|Thermoanaerobacterales 186801|Clostridia S Carbon-nitrogen hydrolase - - 3.5.1.53 ko:K12251 ko00330,ko01100,map00330,map01100 - R01152 RC00096 ko00000,ko00001,ko01000 - - - CN_hydrolase SJTD3_k127_3646071_3 479434.Sthe_0466 1.107e-28 116.0 COG0423@1|root,COG0423@2|Bacteria,2G62M@200795|Chloroflexi,27XGU@189775|Thermomicrobia 189775|Thermomicrobia J Catalyzes the attachment of glycine to tRNA(Gly) - GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b SJTD3_k127_3667329_0 479434.Sthe_3364 3.466e-82 287.0 COG0842@1|root,COG0842@2|Bacteria,2G6PG@200795|Chloroflexi,27Z1H@189775|Thermomicrobia 189775|Thermomicrobia V ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 SJTD3_k127_3667329_2 1382306.JNIM01000001_gene3372 2.48e-76 269.0 COG1131@1|root,COG1131@2|Bacteria,2G6JW@200795|Chloroflexi 200795|Chloroflexi V ABC transporter - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_3667329_1 1128421.JAGA01000002_gene790 1.321e-78 268.0 COG1309@1|root,COG1309@2|Bacteria,2NQ8G@2323|unclassified Bacteria 2|Bacteria K Bacterial regulatory proteins, tetR family - - - ko:K09017 - - - - ko00000,ko03000 - - - TetR_C_11,TetR_C_7,TetR_N SJTD3_k127_3667329_4 234267.Acid_6551 2.269e-20 98.0 COG0298@1|root,COG0298@2|Bacteria,3Y5NM@57723|Acidobacteria 57723|Acidobacteria O PFAM hydrogenase expression formation protein (HUPF HYPC) - - - ko:K04653 - - - - ko00000 - - - HupF_HypC SJTD3_k127_3667329_5 383372.Rcas_1121 5.311e-08 56.0 COG3847@1|root,COG3847@2|Bacteria,2GB1R@200795|Chloroflexi,377RD@32061|Chloroflexia 32061|Chloroflexia U PFAM Flp Fap pilin component - - - ko:K02651 ko04112,map04112 - - - ko00000,ko00001,ko02035,ko02044 - - - Flp_Fap SJTD3_k127_3667329_3 525904.Tter_1017 7.365e-66 244.0 COG2064@1|root,COG2304@1|root,COG2064@2|Bacteria,COG2304@2|Bacteria,2NNYH@2323|unclassified Bacteria 2|Bacteria NU von Willebrand factor (vWF) type A domain tadC - - ko:K07114,ko:K12511 - - - - ko00000,ko02000,ko02044 1.A.13.2.2,1.A.13.2.3 - - T2SSF,VWA,VWA_2 SJTD3_k127_3698717_1 871968.DESME_07815 3.655e-09 66.0 COG1633@1|root,COG1633@2|Bacteria,1VJB9@1239|Firmicutes,24SA5@186801|Clostridia,266AT@186807|Peptococcaceae 186801|Clostridia S Domain of unknown function (DUF2383) - - 1.16.3.1 ko:K03594 ko00860,map00860 - R00078 RC02758 ko00000,ko00001,ko01000 - - - DUF2383 SJTD3_k127_3698717_0 357808.RoseRS_2144 9.34e-103 347.0 COG1625@1|root,COG1625@2|Bacteria,2G5XW@200795|Chloroflexi,374WH@32061|Chloroflexia 32061|Chloroflexia C Protein of unknown function (DUF512) - - - - - - - - - - - - DUF512 SJTD3_k127_3716333_2 485913.Krac_2147 1.665e-44 164.0 COG1024@1|root,COG1024@2|Bacteria,2G6G6@200795|Chloroflexi 2|Bacteria I PFAM Enoyl-CoA hydratase isomerase MA20_38145 - - - - - - - - - - - ECH_1 SJTD3_k127_3716333_1 1382306.JNIM01000001_gene3716 9.072e-102 338.0 COG1028@1|root,COG1028@2|Bacteria,2G8CF@200795|Chloroflexi 200795|Chloroflexi IQ PFAM short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short,adh_short_C2 SJTD3_k127_3716333_0 485913.Krac_2149 5.189e-187 598.0 COG0654@1|root,COG1902@1|root,COG0654@2|Bacteria,COG1902@2|Bacteria,2G872@200795|Chloroflexi 200795|Chloroflexi C PFAM NADH flavin oxidoreductase NADH oxidase - - - - - - - - - - - - Oxidored_FMN SJTD3_k127_3733198_9 391937.NA2_09141 2.695e-12 69.0 2EKB5@1|root,3351G@2|Bacteria,1QYR7@1224|Proteobacteria,2TXX7@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_3733198_8 1089544.KB912942_gene2020 1.707e-24 106.0 COG2151@1|root,COG2151@2|Bacteria,2IKUH@201174|Actinobacteria 201174|Actinobacteria J metal-sulfur cluster biosynthetic enzyme - - - - - - - - - - - - FeS_assembly_P SJTD3_k127_3733198_7 1382356.JQMP01000001_gene798 4.384e-44 169.0 COG4309@1|root,COG4309@2|Bacteria,2G936@200795|Chloroflexi,27ZCU@189775|Thermomicrobia 189775|Thermomicrobia S Uncharacterized conserved protein (DUF2249) - - - - - - - - - - - - DUF2249 SJTD3_k127_3733198_0 666684.AfiDRAFT_2539 5.576e-169 545.0 COG2132@1|root,COG3474@1|root,COG4454@1|root,COG2132@2|Bacteria,COG3474@2|Bacteria,COG4454@2|Bacteria,1MV74@1224|Proteobacteria,2U1BK@28211|Alphaproteobacteria,3JV1C@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C Copper binding proteins, plastocyanin/azurin family - - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase_2,Cu-oxidase_3,Cytochrom_C SJTD3_k127_3733198_6 1123368.AUIS01000035_gene81 2.536e-44 166.0 COG5615@1|root,COG5615@2|Bacteria 2|Bacteria L integral membrane protein - - - - - - - - - - - - CopD SJTD3_k127_3733198_4 330214.NIDE3489 2.529e-107 359.0 COG4243@1|root,COG4243@2|Bacteria 2|Bacteria S quinone binding - - 1.7.2.1 ko:K00368 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - - SJTD3_k127_3733198_2 471852.Tcur_2962 1.466e-162 528.0 COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EI99@85012|Streptosporangiales 201174|Actinobacteria C Berberine and berberine like - - - - - - - - - - - - BBE,FAD_binding_4 SJTD3_k127_3733198_5 489825.LYNGBM3L_22570 1.577e-64 239.0 COG0392@1|root,COG0392@2|Bacteria,1G41A@1117|Cyanobacteria,1HD8Q@1150|Oscillatoriales 1117|Cyanobacteria S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SJTD3_k127_3733198_3 357808.RoseRS_2772 4.505e-136 440.0 COG5564@1|root,COG5564@2|Bacteria,2G7PY@200795|Chloroflexi 200795|Chloroflexi S Phosphoenolpyruvate hydrolase-like - - - - - - - - - - - - PEP_hydrolase SJTD3_k127_3733198_1 357808.RoseRS_2773 5.828e-168 537.0 COG5441@1|root,COG5441@2|Bacteria,2G7QM@200795|Chloroflexi 200795|Chloroflexi S Uncharacterised protein family (UPF0261) - - - - - - - - - - - - UPF0261 SJTD3_k127_3763734_4 1128421.JAGA01000002_gene1158 2.254e-36 141.0 COG1278@1|root,COG1278@2|Bacteria,2NQ3A@2323|unclassified Bacteria 2|Bacteria K Probable zinc-ribbon domain cspA - - ko:K03704 - - - - ko00000,ko03000 - - - CSD,Ribosomal_S30AE,zf-trcl SJTD3_k127_3763734_0 1128421.JAGA01000004_gene2559 7.557e-281 879.0 COG1217@1|root,COG1217@2|Bacteria,2NNY7@2323|unclassified Bacteria 2|Bacteria T Elongation factor G C-terminus typA GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 SJTD3_k127_3763734_8 1206733.BAGC01000041_gene2001 1.379e-07 59.0 2C1AE@1|root,32QZN@2|Bacteria,2IIC0@201174|Actinobacteria,4G0WT@85025|Nocardiaceae 201174|Actinobacteria S DinB superfamily - - - - - - - - - - - - DinB_2 SJTD3_k127_3763734_7 1463881.KL591031_gene3173 1.477e-10 72.0 2E5KE@1|root,3385H@2|Bacteria,2ISK3@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_3763734_5 443598.AUFA01000005_gene3696 8.456e-32 132.0 COG1309@1|root,COG1309@2|Bacteria,1MW6I@1224|Proteobacteria,2UBXJ@28211|Alphaproteobacteria,3JVS9@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K BetI-type transcriptional repressor, C-terminal - - - - - - - - - - - - TetR_C_6,TetR_N SJTD3_k127_3763734_1 215803.DB30_6413 2.248e-74 261.0 COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,42VTI@68525|delta/epsilon subdivisions,2WW2V@28221|Deltaproteobacteria,2YYXY@29|Myxococcales 28221|Deltaproteobacteria HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - - - - - - - - - - GSH-S_ATP SJTD3_k127_3763734_6 1232410.KI421426_gene1319 2.504e-23 104.0 COG0662@1|root,COG0662@2|Bacteria,1QYNW@1224|Proteobacteria 1224|Proteobacteria G AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_3763734_2 1382306.JNIM01000001_gene2608 1.628e-57 206.0 COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi 200795|Chloroflexi J COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - - - - - - - - - - Acetyltransf_3 SJTD3_k127_3763734_3 1382306.JNIM01000001_gene2608 1.284e-54 198.0 COG1670@1|root,COG1670@2|Bacteria,2G6UG@200795|Chloroflexi 200795|Chloroflexi J COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - - - - - - - - - - Acetyltransf_3 SJTD3_k127_377533_2 1347368.HG964403_gene4308 4.529e-06 52.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli,1ZPUS@1386|Bacillus 91061|Bacilli M Cell wall hydrolase autolysin lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH SJTD3_k127_377533_0 926569.ANT_00510 4.655e-54 201.0 COG0061@1|root,COG0061@2|Bacteria,2G6NK@200795|Chloroflexi 200795|Chloroflexi F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK - 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - - NAD_kinase SJTD3_k127_377533_1 479434.Sthe_1208 4.021e-34 135.0 COG1189@1|root,COG1189@2|Bacteria,2G6BX@200795|Chloroflexi,27XW2@189775|Thermomicrobia 189775|Thermomicrobia J FtsJ-like methyltransferase - - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 SJTD3_k127_3794623_1 383372.Rcas_2666 1.236e-160 508.0 COG1879@1|root,COG1879@2|Bacteria,2G8QP@200795|Chloroflexi 200795|Chloroflexi P Periplasmic binding protein domain - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_3794623_0 357808.RoseRS_3057 4.215e-218 686.0 COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi,376BP@32061|Chloroflexia 32061|Chloroflexia P ABC transporter - - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_3794623_3 383372.Rcas_2668 2.707e-128 422.0 COG1172@1|root,COG1172@2|Bacteria,2G8WV@200795|Chloroflexi,377N4@32061|Chloroflexia 32061|Chloroflexia G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057,ko:K10440 ko02010,map02010 M00212,M00221 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_3794623_2 357808.RoseRS_3055 3.67e-146 478.0 COG1172@1|root,COG1172@2|Bacteria,2G8TB@200795|Chloroflexi 200795|Chloroflexi U Belongs to the binding-protein-dependent transport system permease family - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_3794623_6 485915.Dret_0105 3.779e-26 114.0 COG1846@1|root,COG1846@2|Bacteria,1N75F@1224|Proteobacteria,42VDI@68525|delta/epsilon subdivisions,2WR80@28221|Deltaproteobacteria,2MBUI@213115|Desulfovibrionales 28221|Deltaproteobacteria K Transcriptional regulator, marR - - - - - - - - - - - - MarR SJTD3_k127_3794623_4 861299.J421_0746 1.202e-56 202.0 COG2020@1|root,COG2020@2|Bacteria 2|Bacteria O methyltransferase activity - - - - - - - - - - - - PEMT SJTD3_k127_3794623_5 419947.MRA_1447 1.035e-30 126.0 COG3631@1|root,COG3631@2|Bacteria,2GUSJ@201174|Actinobacteria,23C5Y@1762|Mycobacteriaceae 201174|Actinobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 SJTD3_k127_3794623_7 926569.ANT_10770 8.698e-08 55.0 COG0527@1|root,COG0527@2|Bacteria,2G5U9@200795|Chloroflexi 200795|Chloroflexi E Belongs to the aspartokinase family metL - 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase,ACT,ACT_7 SJTD3_k127_3802306_2 404589.Anae109_4224 1.887e-06 59.0 COG3886@1|root,COG3886@2|Bacteria,1PV0V@1224|Proteobacteria,432VP@68525|delta/epsilon subdivisions 1224|Proteobacteria L PLD-like domain - - - - - - - - - - - - PLDc_2 SJTD3_k127_3802306_1 349106.PsycPRwf_0124 3.097e-09 67.0 28IMK@1|root,2Z8N2@2|Bacteria,1R85A@1224|Proteobacteria 1224|Proteobacteria L Dam-replacing family - - 3.1.21.4 ko:K01155 - - - - ko00000,ko01000,ko02048 - - - DpnI SJTD3_k127_3802306_0 1382356.JQMP01000004_gene653 7.326e-39 161.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_3848141_0 357808.RoseRS_1240 9.702e-225 727.0 COG1198@1|root,COG2512@1|root,COG1198@2|Bacteria,COG2512@2|Bacteria,2G60J@200795|Chloroflexi,374T5@32061|Chloroflexia 32061|Chloroflexia L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA - - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C SJTD3_k127_3848141_2 525904.Tter_0050 2.132e-53 203.0 28JN3@1|root,2Z9EI@2|Bacteria 2|Bacteria S Ion transport 2 domain protein - - - - - - - - - - - - Ion_trans_2 SJTD3_k127_3848141_1 1476583.DEIPH_ctg035orf0004 3.353e-66 239.0 COG0598@1|root,COG0598@2|Bacteria 2|Bacteria P Magnesium transport protein CorA corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA SJTD3_k127_3848141_3 479434.Sthe_0382 3.216e-47 177.0 COG0242@1|root,COG0242@2|Bacteria,2G6VE@200795|Chloroflexi,27YB2@189775|Thermomicrobia 189775|Thermomicrobia J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase SJTD3_k127_3848141_5 1041930.Mtc_0636 3.836e-15 88.0 COG5542@1|root,arCOG10055@2157|Archaea 2157|Archaea S dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity - - - - - - - - - - - - Mannosyl_trans2 SJTD3_k127_3848141_4 469383.Cwoe_2994 2.374e-19 94.0 COG1752@1|root,COG1752@2|Bacteria,2ID07@201174|Actinobacteria,4CR54@84995|Rubrobacteria 84995|Rubrobacteria S Patatin-like phospholipase - - - - - - - - - - - - Patatin SJTD3_k127_3862763_0 573413.Spirs_2154 5.478e-141 464.0 COG0215@1|root,COG0215@2|Bacteria,2J618@203691|Spirochaetes 203691|Spirochaetes J Belongs to the class-I aminoacyl-tRNA synthetase family cysS - 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e SJTD3_k127_3862763_2 368408.Tpen_1406 1.49e-07 59.0 arCOG09752@1|root,arCOG09752@2157|Archaea 2157|Archaea - - - - - - - - - - - - - - - SJTD3_k127_3862763_1 314278.NB231_09403 4.468e-22 106.0 COG0553@1|root,COG0553@2|Bacteria,1MV6M@1224|Proteobacteria 1224|Proteobacteria L Helicase - - - - - - - - - - - - Helicase_C,SNF2_N,SWIM SJTD3_k127_3867022_1 935948.KE386495_gene2211 3.208e-55 200.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,42G4B@68295|Thermoanaerobacterales 186801|Clostridia J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.19,5.4.99.22 ko:K06178,ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 SJTD3_k127_3867022_0 1521187.JPIM01000022_gene631 4.046e-59 214.0 COG0283@1|root,COG0283@2|Bacteria,2G6I5@200795|Chloroflexi,375JC@32061|Chloroflexia 32061|Chloroflexia F Belongs to the cytidylate kinase family. Type 1 subfamily cmk - 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin SJTD3_k127_3867022_2 316274.Haur_4246 9.123e-51 185.0 COG0477@1|root,COG0477@2|Bacteria,2G5YG@200795|Chloroflexi 200795|Chloroflexi EGP Major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_3 SJTD3_k127_386791_3 1521187.JPIM01000068_gene752 1.345e-45 170.0 COG0581@1|root,COG0581@2|Bacteria,2G6BI@200795|Chloroflexi,374ZR@32061|Chloroflexia 32061|Chloroflexia P TIGRFAM phosphate ABC transporter, inner membrane subunit PstA - - - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 SJTD3_k127_386791_1 324602.Caur_0265 2.176e-117 385.0 COG0573@1|root,COG0573@2|Bacteria,2G62J@200795|Chloroflexi,375B0@32061|Chloroflexia 32061|Chloroflexia P probably responsible for the translocation of the substrate across the membrane - - - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 SJTD3_k127_386791_0 324602.Caur_0266 1.242e-133 438.0 COG0226@1|root,COG0226@2|Bacteria,2G6FH@200795|Chloroflexi,374S9@32061|Chloroflexia 32061|Chloroflexia P TIGRFAM phosphate binding protein - - - - - - - - - - - - PBP_like,PBP_like_2 SJTD3_k127_386791_6 1121380.JNIW01000047_gene31 3.143e-30 124.0 COG1803@1|root,COG1803@2|Bacteria,1WJTD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G methylglyoxal synthase mgsA - 4.2.3.3 ko:K01734 ko00640,ko01120,map00640,map01120 - R01016 RC00424 ko00000,ko00001,ko01000 - - - MGS SJTD3_k127_386791_9 251221.35211431 1.15e-22 103.0 2EAFX@1|root,334J9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_386791_4 1382356.JQMP01000004_gene653 1.94e-38 164.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_386791_2 338963.Pcar_0624 7.934e-102 355.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,42MU3@68525|delta/epsilon subdivisions,2WKTF@28221|Deltaproteobacteria,43SSU@69541|Desulfuromonadales 28221|Deltaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH SJTD3_k127_386791_10 314254.OA2633_05551 6.517e-06 56.0 COG1266@1|root,COG1266@2|Bacteria,1PV81@1224|Proteobacteria,2V6PS@28211|Alphaproteobacteria,43ZVU@69657|Hyphomonadaceae 28211|Alphaproteobacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi SJTD3_k127_386791_7 485913.Krac_7071 2.886e-26 117.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 SJTD3_k127_386791_8 1001240.GY21_04485 1.627e-23 106.0 COG0716@1|root,COG0716@2|Bacteria 2|Bacteria C FMN binding - - - - - - - - - - - - Flavodoxin_1,Flavodoxin_3,Flavodoxin_5 SJTD3_k127_386791_5 767817.Desgi_3126 1.008e-31 138.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,262UC@186807|Peptococcaceae 186801|Clostridia S X-Pro dipeptidyl-peptidase (S15 family) - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4,Peptidase_S9 SJTD3_k127_3887236_1 309801.trd_1065 9.373e-34 143.0 COG0328@1|root,COG0328@2|Bacteria,2GB0N@200795|Chloroflexi,27YNH@189775|Thermomicrobia 189775|Thermomicrobia L Reverse transcriptase-like - - 3.1.26.4 ko:K03469 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RVT_3 SJTD3_k127_3887236_0 1210884.HG799472_gene14892 1.993e-38 145.0 COG0060@1|root,COG0060@2|Bacteria,2IWX2@203682|Planctomycetes 203682|Planctomycetes J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS SJTD3_k127_3916425_1 1128421.JAGA01000001_gene2270 1.085e-18 87.0 COG0332@1|root,COG0332@2|Bacteria,2NQSU@2323|unclassified Bacteria 2|Bacteria I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C SJTD3_k127_3916425_0 1128421.JAGA01000003_gene2987 0.0 1019.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2NQG9@2323|unclassified Bacteria 2|Bacteria K Bacterial transcriptional activator domain - - - - - - - - - - - - BTAD,TPR_12,Trans_reg_C SJTD3_k127_3926661_3 1382356.JQMP01000003_gene1531 8.46e-13 68.0 COG2340@1|root,COG5479@1|root,COG2340@2|Bacteria,COG5479@2|Bacteria,2GBCS@200795|Chloroflexi,27YT2@189775|Thermomicrobia 189775|Thermomicrobia M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP SJTD3_k127_3926661_1 926569.ANT_14860 7.225e-186 589.0 COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi 200795|Chloroflexi EK PFAM Aminotransferase class I and II - - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2 SJTD3_k127_3926661_0 1173024.KI912153_gene216 0.0 1709.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1G2E2@1117|Cyanobacteria,1JKG2@1189|Stigonemataceae 1117|Cyanobacteria C Domain of unknown function - - 1.2.7.1 ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 M00173,M00307 R01196,R10866 RC00004,RC02742 br01601,ko00000,ko00001,ko00002,ko01000 - - - EKR,Fer4_16,PFOR_II,POR,POR_N,TPP_enzyme_C SJTD3_k127_3926661_2 160799.PBOR_09815 3.29e-18 93.0 29687@1|root,2ZTI7@2|Bacteria,1W1MJ@1239|Firmicutes,4I1VE@91061|Bacilli,2770R@186822|Paenibacillaceae 91061|Bacilli S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi SJTD3_k127_3926999_1 1219084.AP014508_gene184 4.549e-105 354.0 COG1052@1|root,COG1052@2|Bacteria,2GC25@200918|Thermotogae 200918|Thermotogae C D-isomer specific 2-hydroxyacid dehydrogenase catalytic - - 1.1.1.26 ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 - R00717,R01388 RC00031,RC00042 ko00000,ko00001,ko01000 - - - 2-Hacid_dh,2-Hacid_dh_C SJTD3_k127_3926999_0 479434.Sthe_0930 1.622e-300 939.0 COG1111@1|root,COG1205@1|root,COG1111@2|Bacteria,COG1205@2|Bacteria,2G7WU@200795|Chloroflexi,27YR8@189775|Thermomicrobia 189775|Thermomicrobia L helicase superfamily c-terminal domain - - - ko:K06877 - - - - ko00000 - - - DEAD,DUF1998,Helicase_C SJTD3_k127_3926999_2 309801.trd_1030 2.638e-41 170.0 COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi,27XKD@189775|Thermomicrobia 189775|Thermomicrobia U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - SJTD3_k127_3926999_3 1499967.BAYZ01000195_gene3091 4.696e-16 91.0 COG4447@1|root,COG4447@2|Bacteria,2NQ6W@2323|unclassified Bacteria 2|Bacteria S Por secretion system C-terminal sorting domain-containing protein - - - - - - - - - - - - Peptidase_S8,Sortilin-Vps10 SJTD3_k127_3934794_6 927677.ALVU02000001_gene4459 5.977e-14 74.0 COG2389@1|root,COG2389@2|Bacteria,1G6XV@1117|Cyanobacteria,1H5R2@1142|Synechocystis 1117|Cyanobacteria S Uncharacterized metal-binding protein (DUF2227) - - - - - - - - - - - - DUF2227 SJTD3_k127_3934794_4 1124780.ANNU01000074_gene751 8.559e-30 130.0 COG0494@1|root,COG0494@2|Bacteria,4NM6C@976|Bacteroidetes,47MQZ@768503|Cytophagia 976|Bacteroidetes L pfam nudix - - - - - - - - - - - - NUDIX SJTD3_k127_3934794_0 706587.Desti_2231 8.284e-115 389.0 COG0247@1|root,COG0247@2|Bacteria,1MWTK@1224|Proteobacteria,42MMF@68525|delta/epsilon subdivisions,2WJ1F@28221|Deltaproteobacteria,2MRA9@213462|Syntrophobacterales 28221|Deltaproteobacteria C PFAM Cysteine-rich domain - - - ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 - R00475 RC00042 ko00000,ko00001 - - - CCG,Fer4_8 SJTD3_k127_3934794_2 324602.Caur_3916 2.43e-71 250.0 COG1335@1|root,COG1335@2|Bacteria,2G6JY@200795|Chloroflexi,375H0@32061|Chloroflexia 32061|Chloroflexia Q Isochorismatase family - - - - - - - - - - - - Isochorismatase SJTD3_k127_3934794_5 316274.Haur_0149 5.329e-20 96.0 COG1051@1|root,COG1051@2|Bacteria,2G9MA@200795|Chloroflexi 200795|Chloroflexi F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX SJTD3_k127_3934794_3 479434.Sthe_3074 4.714e-34 138.0 COG1011@1|root,COG1011@2|Bacteria,2G74Q@200795|Chloroflexi 200795|Chloroflexi S DinB superfamily - - - - - - - - - - - - DinB_2 SJTD3_k127_3934794_1 316274.Haur_3632 1.818e-96 324.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria 2|Bacteria E methylenetetrahydrofolate reductase (NAD(P)H) activity yitJ - 1.5.1.20,2.1.1.10,2.1.1.13 ko:K00297,ko:K00547,ko:K00548 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523 M00017,M00377 R00650,R00946,R01224,R07168,R09365 RC00003,RC00035,RC00081,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0504 MTHFR,S-methyl_trans SJTD3_k127_3936705_4 404589.Anae109_2879 2.897e-07 59.0 COG4747@1|root,COG4747@2|Bacteria,1RDCG@1224|Proteobacteria,42RTD@68525|delta/epsilon subdivisions,2WNC2@28221|Deltaproteobacteria 28221|Deltaproteobacteria S PFAM amino acid-binding ACT domain protein - - - - - - - - - - - - ACT SJTD3_k127_3936705_1 926550.CLDAP_33500 1.994e-62 225.0 COG1122@1|root,COG1122@2|Bacteria,2G6FK@200795|Chloroflexi 200795|Chloroflexi P ECF transporter, substrate-specific component - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF_trnsprt SJTD3_k127_3936705_0 326427.Cagg_2501 9.339e-169 546.0 COG1122@1|root,COG1122@2|Bacteria,2G5RY@200795|Chloroflexi,377ZZ@32061|Chloroflexia 32061|Chloroflexia P PFAM ABC transporter related - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran SJTD3_k127_3936705_3 926550.CLDAP_33510 7.788e-40 162.0 COG0619@1|root,COG0619@2|Bacteria,2G71W@200795|Chloroflexi 200795|Chloroflexi P Cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ SJTD3_k127_3936705_2 1128421.JAGA01000002_gene227 1.721e-41 165.0 COG1657@1|root,COG1657@2|Bacteria 2|Bacteria I PFAM Prenyltransferase squalene oxidase - - - - - - - - - - - - - SJTD3_k127_3938391_1 326427.Cagg_2708 2.669e-54 197.0 COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,2G60Q@200795|Chloroflexi,3762Z@32061|Chloroflexia 32061|Chloroflexia T histidine kinase HAMP region domain protein - - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA SJTD3_k127_3938391_2 1121272.KB903249_gene1521 1.174e-13 86.0 COG1404@1|root,COG2133@1|root,COG3291@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,2GJFY@201174|Actinobacteria,4DASA@85008|Micromonosporales 201174|Actinobacteria G Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - Big_5,CarboxypepD_reg,F5_F8_type_C,GSDH,PA14,PKD SJTD3_k127_3938391_3 1123290.AUDQ01000022_gene745 4.539e-10 74.0 COG0791@1|root,COG0791@2|Bacteria,1V9FW@1239|Firmicutes,4HISN@91061|Bacilli,26FSP@186818|Planococcaceae 91061|Bacilli M S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_3938391_0 446470.Snas_0537 1.046e-117 420.0 COG3055@1|root,COG3055@2|Bacteria 2|Bacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - Big_2,Kelch_1,Kelch_3,Kelch_6 SJTD3_k127_3938391_4 1132442.KB889752_gene1348 0.0001167 48.0 COG0726@1|root,COG1073@1|root,COG0726@2|Bacteria,COG1073@2|Bacteria,1TSFY@1239|Firmicutes,4HDNK@91061|Bacilli,1ZCJW@1386|Bacillus 91061|Bacilli G Serine aminopeptidase, S33 - - - ko:K06889 - - - - ko00000 - - - Abhydrolase_6,Cu_amine_oxidN1,DUF3887,Hydrolase_4,Peptidase_S9,SLH SJTD3_k127_3941752_3 1437824.BN940_14136 8.241e-10 69.0 28IIF@1|root,2Z8JJ@2|Bacteria,1NUA0@1224|Proteobacteria 1224|Proteobacteria - - - - 4.2.1.127,5.4.4.4 ko:K20614 - - - - ko00000,ko01000 - - - - SJTD3_k127_3941752_0 1192034.CAP_5918 1.141e-209 663.0 COG1690@1|root,COG1690@2|Bacteria,1MUHA@1224|Proteobacteria,42MZN@68525|delta/epsilon subdivisions,2WJGK@28221|Deltaproteobacteria,2YY2T@29|Myxococcales 28221|Deltaproteobacteria S tRNA-splicing ligase RtcB - - 6.5.1.3 ko:K14415 - - - - ko00000,ko01000,ko03016 - - - RtcB SJTD3_k127_3941752_2 479431.Namu_0365 8.94e-27 121.0 29YCS@1|root,30K75@2|Bacteria,2IJFN@201174|Actinobacteria,4EXJ6@85013|Frankiales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_3941752_1 1121011.AUCB01000013_gene245 1.146e-28 118.0 COG1028@1|root,COG1028@2|Bacteria,4NH6Y@976|Bacteroidetes,1HXA4@117743|Flavobacteriia,23GTX@178469|Arenibacter 976|Bacteroidetes IQ KR domain - - - - - - - - - - - - adh_short_C2 SJTD3_k127_3942760_0 880073.Calab_1670 6.872e-136 448.0 COG0520@1|root,COG0520@2|Bacteria,2NNS0@2323|unclassified Bacteria 2|Bacteria E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine csdA - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 SJTD3_k127_3950654_0 269800.Tfu_2491 3.109e-53 198.0 COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria,4EIFM@85012|Streptosporangiales 201174|Actinobacteria T helix_turn_helix, Lux Regulon - - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg SJTD3_k127_3950654_1 383372.Rcas_1439 1.769e-11 73.0 COG1928@1|root,COG1928@2|Bacteria,2G8YA@200795|Chloroflexi,375IA@32061|Chloroflexia 32061|Chloroflexia O C-terminal four TMM region of protein-O-mannosyltransferase - - - - - - - - - - - - - SJTD3_k127_3951987_2 1283299.AUKG01000005_gene133 1.436e-21 100.0 COG1028@1|root,COG1028@2|Bacteria,2GXKF@201174|Actinobacteria,4CS3Z@84995|Rubrobacteria 84995|Rubrobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - - SJTD3_k127_3951987_1 525904.Tter_2215 1.476e-247 779.0 COG3533@1|root,COG3533@2|Bacteria,2NNW0@2323|unclassified Bacteria 2|Bacteria S Beta-L-arabinofuranosidase, GH127 - - - ko:K09955 - - - - ko00000 - - - Glyco_hydro_127 SJTD3_k127_3951987_0 357808.RoseRS_0780 8.675e-279 874.0 COG0438@1|root,COG0500@1|root,COG0438@2|Bacteria,COG2226@2|Bacteria,2G84C@200795|Chloroflexi,375HH@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Methyltransf_11 SJTD3_k127_3957553_2 1128421.JAGA01000002_gene1729 1.424e-46 178.0 COG2521@1|root,COG2521@2|Bacteria,2NQ9R@2323|unclassified Bacteria 2|Bacteria S Spermine/spermidine synthase domain ypiP - 2.1.1.242 ko:K06983,ko:K15984 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_11,Methyltransf_30,SAM_MT SJTD3_k127_3957553_1 1173027.Mic7113_2544 1.113e-68 244.0 COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1H9BW@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Ribonuclease BN-like family - - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB SJTD3_k127_3957553_0 1128421.JAGA01000004_gene2626 7.672e-110 364.0 COG1089@1|root,COG1089@2|Bacteria,2NP6U@2323|unclassified Bacteria 2|Bacteria M Polysaccharide biosynthesis protein - - 1.1.1.281 ko:K15856 ko00051,ko00520,map00051,map00520 - R03397,R03399 RC00182 ko00000,ko00001,ko01000 - - - GDP_Man_Dehyd SJTD3_k127_3961041_1 1158294.JOMI01000001_gene1747 3.38e-07 58.0 COG1765@1|root,COG1765@2|Bacteria,4NM9D@976|Bacteroidetes 976|Bacteroidetes O OsmC-like protein - - - - - - - - - - - - OsmC SJTD3_k127_3961041_0 1280380.KR100_13330 6.878e-62 219.0 COG0111@1|root,COG0111@2|Bacteria,1FZZU@1117|Cyanobacteria,1GZ6T@1129|Synechococcus 1117|Cyanobacteria E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT SJTD3_k127_3962315_1 1280696.ATVY01000008_gene1924 5.296e-18 97.0 29UDH@1|root,30FQ5@2|Bacteria,1UEE7@1239|Firmicutes,25JAI@186801|Clostridia,4C0X6@830|Butyrivibrio 186801|Clostridia - - - - - - - - - - - - - - - SJTD3_k127_3962315_0 765420.OSCT_1347 1.823e-79 274.0 COG1066@1|root,COG1066@2|Bacteria,2G5TE@200795|Chloroflexi,37554@32061|Chloroflexia 32061|Chloroflexia L DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ChlI SJTD3_k127_3965387_9 1196031.ALEG01000029_gene3871 6.447e-24 105.0 2DMHQ@1|root,32RMG@2|Bacteria,1VB95@1239|Firmicutes,4HKKS@91061|Bacilli,1ZGRX@1386|Bacillus 91061|Bacilli S Arsenical resistance operon trans-acting repressor ArsD - - - - - - - - - - - - ArsD SJTD3_k127_3965387_8 926550.CLDAP_40610 3.536e-39 151.0 COG0640@1|root,COG0640@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K03892 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 SJTD3_k127_3965387_1 1382306.JNIM01000001_gene2810 3.91e-146 470.0 COG1082@1|root,COG1082@2|Bacteria 2|Bacteria G myo-inosose-2 dehydratase activity - - 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 SJTD3_k127_3965387_6 1382306.JNIM01000001_gene2809 1.078e-117 386.0 COG3959@1|root,COG3959@2|Bacteria,2GA6J@200795|Chloroflexi 200795|Chloroflexi G Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N SJTD3_k127_3965387_4 1382306.JNIM01000001_gene2808 6.121e-136 440.0 COG3958@1|root,COG3958@2|Bacteria,2G8E1@200795|Chloroflexi 200795|Chloroflexi G Transketolase, pyrimidine binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C SJTD3_k127_3965387_2 717605.Theco_0520 5.112e-145 480.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,4H9ZF@91061|Bacilli,26QJT@186822|Paenibacillaceae 91061|Bacilli C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N SJTD3_k127_3965387_5 1382306.JNIM01000001_gene2806 2.278e-119 392.0 COG2390@1|root,COG2390@2|Bacteria,2G8CS@200795|Chloroflexi 200795|Chloroflexi K Putative sugar-binding domain - - - - - - - - - - - - Sigma70_r4,Sugar-bind SJTD3_k127_3965387_7 1382306.JNIM01000001_gene2805 3.574e-48 181.0 COG5618@1|root,COG5618@2|Bacteria 2|Bacteria S Predicted periplasmic lipoprotein (DUF2291) - - - - - - - - - - - - DUF2291 SJTD3_k127_3965387_0 1382306.JNIM01000001_gene2804 3.641e-194 619.0 COG1129@1|root,COG1129@2|Bacteria 2|Bacteria G ABC transporter rbsA_1 - 3.6.3.17 ko:K10441,ko:K17204 ko02010,map02010 M00212,M00590 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19 - - ABC_tran SJTD3_k127_3965387_3 1121346.KB899812_gene2132 1.408e-139 452.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4HVD4@91061|Bacilli,272D1@186822|Paenibacillaceae 91061|Bacilli G Branched-chain amino acid transport system / permease component - - - ko:K17203 ko02010,map02010 M00590 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.11,3.A.1.2.16 - - BPD_transp_2 SJTD3_k127_3965387_10 1121346.KB899812_gene2135 1.141e-20 99.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli,26SYM@186822|Paenibacillaceae 91061|Bacilli G Periplasmic substrate-binding component of the ATP-dependent ribose transport system rbsB3 - - ko:K10439,ko:K17202 ko02010,ko02030,map02010,map02030 M00212,M00590 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_3969531_2 55207.KP22_14560 2.704e-35 140.0 COG1310@1|root,COG1310@2|Bacteria,1QRZQ@1224|Proteobacteria,1S558@1236|Gammaproteobacteria 1236|Gammaproteobacteria S JAB1/Mov34/MPN/PAD-1 ubiquitin protease - - - - - - - - - - - - Prok-JAB SJTD3_k127_3969531_0 1303518.CCALI_00534 3.045e-114 378.0 COG0031@1|root,COG0031@2|Bacteria 2|Bacteria E Belongs to the cysteine synthase cystathionine beta- synthase family cysM GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 ko:K12339,ko:K21148 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04122,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04122 M00021 R00897,R03132,R03601,R04859,R10610 RC00020,RC02814,RC02821,RC02876,RC03225 ko00000,ko00001,ko00002,ko01000 - - - PALP SJTD3_k127_3969531_1 1463845.JOIG01000009_gene3202 8.144e-45 169.0 COG0640@1|root,COG0640@2|Bacteria,2IIA5@201174|Actinobacteria 201174|Actinobacteria K Helix-turn-helix domain - - - - - - - - - - - - HTH_20 SJTD3_k127_3969531_3 485913.Krac_1772 3.853e-21 94.0 COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SJTD3_k127_3969893_0 215803.DB30_7610 1.057e-51 207.0 COG0823@1|root,COG4932@1|root,COG0823@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria,43C2M@68525|delta/epsilon subdivisions,2X7D7@28221|Deltaproteobacteria,2Z3FP@29|Myxococcales 28221|Deltaproteobacteria MU PKD domain - - - - - - - - - - - - PKD SJTD3_k127_3969893_1 485913.Krac_4939 1.979e-18 91.0 COG2120@1|root,COG2120@2|Bacteria,2G9IP@200795|Chloroflexi 200795|Chloroflexi S GlcNAc-PI de-N-acetylase - - - - - - - - - - - - PIG-L SJTD3_k127_3977971_3 926550.CLDAP_38580 1.847e-61 213.0 COG2376@1|root,COG2376@2|Bacteria,2G80E@200795|Chloroflexi 2|Bacteria G TIGRFAM dihydroxyacetone kinase, DhaK subunit - - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05878,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Dak1,Dak2 SJTD3_k127_3977971_2 926550.CLDAP_38590 7.625e-70 242.0 COG1461@1|root,COG1461@2|Bacteria 2|Bacteria S glycerone kinase activity dhaL - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 M00344 R01011,R01012,R01059 RC00002,RC00015,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Dak1,Dak2 SJTD3_k127_3977971_0 1128421.JAGA01000001_gene2227 5.791e-219 686.0 COG0402@1|root,COG0402@2|Bacteria 2|Bacteria F S-adenosylhomocysteine deaminase activity atzB - - - - - - - - - - - Amidohydro_1 SJTD3_k127_3977971_1 1121472.AQWN01000004_gene813 2.185e-89 301.0 COG3383@1|root,COG3383@2|Bacteria,1TT6D@1239|Firmicutes,24YN9@186801|Clostridia,267CA@186807|Peptococcaceae 186801|Clostridia C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family fdhA - 1.17.1.10,1.17.1.9 ko:K00123,ko:K05299 ko00630,ko00680,ko00720,ko01100,ko01120,ko01200,map00630,map00680,map00720,map01100,map01120,map01200 M00377 R00134,R00519 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer2_4,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 SJTD3_k127_3980892_1 1121920.AUAU01000006_gene258 2.113e-77 274.0 COG2235@1|root,COG2235@2|Bacteria,3Y86Y@57723|Acidobacteria 57723|Acidobacteria E Amidinotransferase - - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf SJTD3_k127_3980892_2 1121920.AUAU01000006_gene258 9.607e-06 47.0 COG2235@1|root,COG2235@2|Bacteria,3Y86Y@57723|Acidobacteria 57723|Acidobacteria E Amidinotransferase - - 3.5.3.6 ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 - R00552 RC00177 ko00000,ko00001,ko01000 - - - Amidinotransf SJTD3_k127_3980892_0 1242864.D187_006652 1.276e-95 321.0 COG0657@1|root,COG0657@2|Bacteria,1RGPG@1224|Proteobacteria,43C27@68525|delta/epsilon subdivisions,2X7CS@28221|Deltaproteobacteria,2YZQH@29|Myxococcales 28221|Deltaproteobacteria I alpha/beta hydrolase fold - - - - - - - - - - - - Peptidase_S9 SJTD3_k127_3980892_3 633149.Bresu_1737 2.792e-05 49.0 COG3729@1|root,COG3729@2|Bacteria,1NFX9@1224|Proteobacteria,2UJ1W@28211|Alphaproteobacteria,2KHC2@204458|Caulobacterales 204458|Caulobacterales S Stress-induced bacterial acidophilic repeat motif - - - ko:K06884 - - - - ko00000 - - - KGG SJTD3_k127_3982791_1 595460.RRSWK_05503 2.123e-59 239.0 COG1572@1|root,COG2931@1|root,COG3291@1|root,COG3386@1|root,COG3420@1|root,COG4257@1|root,COG1572@2|Bacteria,COG2931@2|Bacteria,COG3291@2|Bacteria,COG3386@2|Bacteria,COG3420@2|Bacteria,COG4257@2|Bacteria,2J2YS@203682|Planctomycetes 203682|Planctomycetes P antibiotic catabolic process - - - - - - - - - - - - - SJTD3_k127_3982791_4 1128421.JAGA01000001_gene2126 1.915e-13 87.0 COG1075@1|root,COG1075@2|Bacteria 2|Bacteria KLT acetyltransferases and hydrolases with the alpha beta hydrolase fold lipA1 - - - - - - - - - - - Abhydrolase_6,DUF11,DUF676,DUF915,LCAT,Lipase_2,PGAP1 SJTD3_k127_3982791_7 386456.JQKN01000005_gene567 0.0002802 57.0 COG1429@1|root,arCOG02555@1|root,arCOG07611@1|root,arCOG02555@2157|Archaea,arCOG03022@2157|Archaea,arCOG07611@2157|Archaea 2157|Archaea E Conserved repeat domain - - - - - - - - - - - - Big_1,CarboxypepD_reg,DUF11 SJTD3_k127_3982791_5 1121957.ATVL01000006_gene2766 3.308e-08 70.0 COG3291@1|root,COG3291@2|Bacteria,4NJHV@976|Bacteroidetes,47R0V@768503|Cytophagia 976|Bacteroidetes S Fibronectin type 3 domain - - - - - - - - - - - - fn3 SJTD3_k127_3982791_0 1121957.ATVL01000014_gene1459 9.558e-134 486.0 COG5563@1|root,COG5563@2|Bacteria,4PHUI@976|Bacteroidetes,47VHU@768503|Cytophagia 976|Bacteroidetes - - - - - - - - - - - - - - - SJTD3_k127_3982791_6 35754.JNYJ01000024_gene9108 6.04e-06 62.0 COG2273@1|root,COG2273@2|Bacteria,2GKFN@201174|Actinobacteria,4D9FP@85008|Micromonosporales 201174|Actinobacteria G F5/8 type C domain - - - - - - - - - - - - CHB_HEX_C_1,F5_F8_type_C SJTD3_k127_3982791_3 65497.JODV01000002_gene4148 6.406e-19 105.0 COG1404@1|root,COG1404@2|Bacteria,2IEGJ@201174|Actinobacteria,4DXZF@85010|Pseudonocardiales 201174|Actinobacteria O Carboxypeptidase regulatory-like domain - - - - - - - - - - - - CARDB,CarboxypepD_reg,Malectin,Peptidase_S8 SJTD3_k127_3982791_2 225849.swp_0164 5.753e-28 122.0 COG1470@1|root,COG3391@1|root,COG1470@2|Bacteria,COG3391@2|Bacteria,1QXEX@1224|Proteobacteria,1T39Y@1236|Gammaproteobacteria,2QAPE@267890|Shewanellaceae 1236|Gammaproteobacteria S Calx-beta domain - - - - - - - - - - - - Calx-beta,CarboxypepD_reg SJTD3_k127_3990705_3 243090.RB10653 4.094e-33 145.0 COG0520@1|root,COG0520@2|Bacteria,2IXCD@203682|Planctomycetes 203682|Planctomycetes E selenocysteine lyase - - - - - - - - - - - - Aminotran_5 SJTD3_k127_3990705_0 485913.Krac_1187 1.94e-105 352.0 COG1171@1|root,COG1171@2|Bacteria,2G69F@200795|Chloroflexi 200795|Chloroflexi E PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP SJTD3_k127_3990705_1 861299.J421_1051 2.091e-75 265.0 COG3910@1|root,COG3910@2|Bacteria,1ZV0R@142182|Gemmatimonadetes 142182|Gemmatimonadetes S AAA domain - - - - - - - - - - - - AAA_21,AAA_23 SJTD3_k127_3990705_2 485913.Krac_6436 3.877e-44 166.0 COG3576@1|root,COG3576@2|Bacteria 2|Bacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx SJTD3_k127_4001632_2 215803.DB30_2061 4.649e-120 393.0 COG3271@1|root,COG3271@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF3335,Peptidase_C39,Peptidase_C39_2 SJTD3_k127_4001632_0 926550.CLDAP_27060 0.0 1763.0 COG0366@1|root,COG4733@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,2G7WY@200795|Chloroflexi 200795|Chloroflexi G Belongs to the glycosyl hydrolase 13 family - - - - - - - - - - - - Alpha-amylase,CBM_20,fn3 SJTD3_k127_4001632_1 1123368.AUIS01000005_gene431 2.982e-237 743.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism narB - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_400863_0 525904.Tter_2256 2.779e-292 915.0 COG0247@1|root,COG1139@1|root,COG0247@2|Bacteria,COG1139@2|Bacteria,2NQQF@2323|unclassified Bacteria 2|Bacteria C LUD domain lutB - - ko:K00782,ko:K18929 - - - - ko00000 - - - CCG,DUF3390,Fer4_8,LUD_dom SJTD3_k127_400863_2 525904.Tter_2255 1.204e-31 131.0 COG1556@1|root,COG1556@2|Bacteria,2NRWC@2323|unclassified Bacteria 2|Bacteria S LUD domain - - - ko:K00782 - - - - ko00000 - - - LUD_dom SJTD3_k127_400863_1 590998.Celf_3013 5.778e-42 156.0 COG0235@1|root,COG0235@2|Bacteria,2IB1Y@201174|Actinobacteria 201174|Actinobacteria G Aldolase - - 4.1.2.19 ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01785,R02263 RC00438,RC00599,RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II SJTD3_k127_4035240_2 485913.Krac_10031 3.609e-64 241.0 COG3559@1|root,COG3559@2|Bacteria,2G7I8@200795|Chloroflexi 200795|Chloroflexi M ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_2 SJTD3_k127_4035240_1 58123.JOFJ01000012_gene5363 1.372e-83 288.0 COG2267@1|root,COG2267@2|Bacteria,2GIVB@201174|Actinobacteria,4EFUF@85012|Streptosporangiales 201174|Actinobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Hydrolase_4 SJTD3_k127_4035240_0 485913.Krac_10032 4.261e-93 317.0 COG1131@1|root,COG1131@2|Bacteria,2G5QI@200795|Chloroflexi 200795|Chloroflexi V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_4035240_4 1128421.JAGA01000002_gene846 1.582e-29 124.0 COG3304@1|root,COG3304@2|Bacteria,2NRKW@2323|unclassified Bacteria 2|Bacteria S Inner membrane component domain yccF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - YccF SJTD3_k127_4035240_6 479434.Sthe_2402 2.451e-05 55.0 COG2834@1|root,COG2834@2|Bacteria,2GBFM@200795|Chloroflexi,27ZBH@189775|Thermomicrobia 189775|Thermomicrobia M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - - SJTD3_k127_4035240_5 1223523.H340_30548 4.6e-28 121.0 COG0638@1|root,COG0638@2|Bacteria,2IHBU@201174|Actinobacteria 201174|Actinobacteria O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - - - - - - - - - - - SJTD3_k127_4035240_3 525904.Tter_0667 2.686e-57 206.0 COG2259@1|root,COG2259@2|Bacteria,2NQ22@2323|unclassified Bacteria 2|Bacteria S DoxX doxD - - ko:K15977 - - - - ko00000 - - - DoxX SJTD3_k127_40370_6 926550.CLDAP_32530 1.323e-15 80.0 COG3576@1|root,COG3576@2|Bacteria,2GA9W@200795|Chloroflexi 200795|Chloroflexi S Pfam:Pyridox_oxidase - - - - - - - - - - - - Putative_PNPOx SJTD3_k127_40370_2 479434.Sthe_3156 1.403e-122 400.0 COG0803@1|root,COG0803@2|Bacteria,2G8F6@200795|Chloroflexi,27XHP@189775|Thermomicrobia 200795|Chloroflexi P Belongs to the bacterial solute-binding protein 9 family - - - ko:K09818,ko:K11707 ko02010,map02010 M00243,M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ZnuA SJTD3_k127_40370_3 880073.Calab_1772 9.016e-119 387.0 COG1121@1|root,COG1121@2|Bacteria,2NPKC@2323|unclassified Bacteria 2|Bacteria P ATPases associated with a variety of cellular activities mntB - - ko:K09817,ko:K11710 ko02010,map02010 M00242,M00319 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU30760 ABC_tran SJTD3_k127_40370_1 880073.Calab_1771 7.851e-129 422.0 COG1108@1|root,COG1108@2|Bacteria,2NPC2@2323|unclassified Bacteria 2|Bacteria U ABC 3 transport family mntC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11708 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC-3,Fe_dep_repr_C SJTD3_k127_40370_0 479434.Sthe_3153 4.123e-141 456.0 COG1108@1|root,COG1108@2|Bacteria,2G7XS@200795|Chloroflexi 200795|Chloroflexi P PFAM ABC-3 protein - - - ko:K11709 ko02010,map02010 M00319 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15 - - ABC-3 SJTD3_k127_40370_5 357808.RoseRS_4127 3.58e-33 134.0 COG0791@1|root,COG3807@1|root,COG0791@2|Bacteria,COG3807@2|Bacteria,2G99E@200795|Chloroflexi,3759J@32061|Chloroflexia 32061|Chloroflexia M SH3, type 3 domain protein - - - - - - - - - - - - NLPC_P60,SH3_3 SJTD3_k127_40370_4 485913.Krac_10955 2.019e-74 261.0 COG1940@1|root,COG1940@2|Bacteria,2G6I0@200795|Chloroflexi 200795|Chloroflexi GK PFAM ROK family protein - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK SJTD3_k127_4044098_0 1521187.JPIM01000196_gene3600 5.376e-137 454.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups rgpA - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glyco_trans_1_4,Glycos_transf_1 SJTD3_k127_4044098_1 208596.CAR_c15460 2.923e-45 180.0 COG0438@1|root,COG0438@2|Bacteria,1TR6R@1239|Firmicutes,4HEIZ@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_4044098_2 383372.Rcas_4176 6.54e-28 123.0 COG0500@1|root,COG2226@2|Bacteria,2GBRI@200795|Chloroflexi,3769K@32061|Chloroflexia 32061|Chloroflexia H PFAM Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_25 SJTD3_k127_4054999_0 326427.Cagg_3026 4.994e-224 698.0 COG0050@1|root,COG0050@2|Bacteria,2G5KI@200795|Chloroflexi,37531@32061|Chloroflexia 32061|Chloroflexia J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf - - ko:K02358 - - - - ko00000,ko03012,ko03029,ko04147 - - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 SJTD3_k127_4054999_1 243164.DET0996 2.124e-18 85.0 COG0267@1|root,COG0267@2|Bacteria,2G7GT@200795|Chloroflexi,34DID@301297|Dehalococcoidia 301297|Dehalococcoidia J structural constituent of ribosome rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 SJTD3_k127_4068323_2 525904.Tter_1349 2.275e-36 152.0 COG0542@1|root,COG0542@2|Bacteria,2NNKN@2323|unclassified Bacteria 2|Bacteria O C-terminal, D2-small domain, of ClpB protein clpC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR SJTD3_k127_4068323_3 926550.CLDAP_05380 2.293e-22 103.0 COG2318@1|root,COG2318@2|Bacteria,2G7AU@200795|Chloroflexi 200795|Chloroflexi S PFAM DinB family protein - - - - - - - - - - - - DinB SJTD3_k127_4068323_4 485913.Krac_7038 1.009e-17 89.0 2BVHN@1|root,32SWN@2|Bacteria 2|Bacteria S Pfam:DUF385 - - - - - - - - - - - - F420H2_quin_red SJTD3_k127_4068323_1 47763.JNZA01000022_gene2753 2.694e-111 366.0 COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria 201174|Actinobacteria K belongs to the sigma-70 factor family, ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2,SnoaL_2 SJTD3_k127_4068323_0 383372.Rcas_1884 1.175e-227 713.0 COG1486@1|root,COG1486@2|Bacteria,2G5M6@200795|Chloroflexi 200795|Chloroflexi G Family 4 glycosyl hydrolase - - 3.2.1.22 ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_4,Glyco_hydro_4C SJTD3_k127_4077647_3 383372.Rcas_1762 7.666e-49 188.0 COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia 32061|Chloroflexia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp SJTD3_k127_4077647_5 1380356.JNIK01000013_gene4175 6.173e-26 111.0 COG4101@1|root,COG4101@2|Bacteria,2II42@201174|Actinobacteria 201174|Actinobacteria G PFAM Cupin 2, conserved barrel - - - - - - - - - - - - Cupin_2 SJTD3_k127_4077647_2 326427.Cagg_2198 1.273e-66 246.0 COG3042@1|root,COG3042@2|Bacteria,2GAFX@200795|Chloroflexi,375ZY@32061|Chloroflexia 32061|Chloroflexia S Domain of unknown function (DUF333) - - - ko:K14475 ko05143,map05143 - - - ko00000,ko00001 - - - DUF333 SJTD3_k127_4077647_4 485913.Krac_8232 1.137e-43 177.0 COG0477@1|root,COG2814@2|Bacteria,2GBNR@200795|Chloroflexi 200795|Chloroflexi EGP Transmembrane secretion effector - - - - - - - - - - - - - SJTD3_k127_4077647_1 316274.Haur_0012 1.264e-95 339.0 COG0823@1|root,COG0823@2|Bacteria,2GAJ0@200795|Chloroflexi,376FZ@32061|Chloroflexia 32061|Chloroflexia U PFAM WD40 domain protein beta Propeller - - - - - - - - - - - - PD40 SJTD3_k127_4077647_0 479432.Sros_1870 1.677e-189 600.0 COG0017@1|root,COG0017@2|Bacteria,2I2KQ@201174|Actinobacteria,4ENTA@85012|Streptosporangiales 201174|Actinobacteria J L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp aspS - 6.1.1.12,6.1.1.23 ko:K01876,ko:K09759 ko00970,map00970 M00359,M00360 R03647,R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - tRNA-synt_2,tRNA_anti-codon SJTD3_k127_4106836_2 644966.Tmar_1214 3.638e-20 97.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,24FZX@186801|Clostridia,3WDBM@538999|Clostridiales incertae sedis 186801|Clostridia K helix_turn_helix, Lux Regulon degU - - - - - - - - - - - GerE,Response_reg SJTD3_k127_4106836_0 326427.Cagg_0340 1.715e-79 271.0 COG2197@1|root,COG2197@2|Bacteria,2G6C5@200795|Chloroflexi,377YJ@32061|Chloroflexia 32061|Chloroflexia K Sigma-70, region 4 type 2 - - - ko:K11618 ko02020,map02020 M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg SJTD3_k127_4106836_1 324602.Caur_3229 1.232e-56 215.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G8GW@200795|Chloroflexi,3776B@32061|Chloroflexia 32061|Chloroflexia T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,HATPase_c,HisKA_3 SJTD3_k127_4110466_1 552811.Dehly_0745 2.552e-32 128.0 COG0311@1|root,COG0311@2|Bacteria,2G6JN@200795|Chloroflexi,34D43@301297|Dehalococcoidia 301297|Dehalococcoidia F Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT - 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO SJTD3_k127_4110466_0 525904.Tter_0684 1.921e-126 411.0 COG3854@1|root,COG3854@2|Bacteria,2NQEN@2323|unclassified Bacteria 2|Bacteria S R3H domain ycf45 - - - - - - - - - - - AAA,AAA_30,R3H SJTD3_k127_4121452_0 765420.OSCT_2952 1.07e-161 538.0 COG0514@1|root,COG0514@2|Bacteria,2G6S8@200795|Chloroflexi,376TB@32061|Chloroflexia 32061|Chloroflexia L RecQ zinc-binding - - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecQ_Zn_bind SJTD3_k127_4121452_1 263358.VAB18032_06090 1.691e-15 80.0 COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4DAGF@85008|Micromonosporales 201174|Actinobacteria H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) menG GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00116,M00117 R04990,R04993,R06859,R08774,R09736 RC00003,RC01253,RC01662 ko00000,ko00001,ko00002,ko01000 - - - Ubie_methyltran SJTD3_k127_4122975_0 88036.EFJ28103 4.441e-149 481.0 COG0442@1|root,KOG4163@2759|Eukaryota,37QBN@33090|Viridiplantae,3GFUW@35493|Streptophyta 35493|Streptophyta J Proline--tRNA - GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009532,GO:0009536,GO:0009553,GO:0009570,GO:0009791,GO:0009908,GO:0009987,GO:0010109,GO:0010154,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019222,GO:0019538,GO:0019752,GO:0022414,GO:0031323,GO:0032501,GO:0032502,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035670,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048229,GO:0048316,GO:0048367,GO:0048437,GO:0048438,GO:0048440,GO:0048467,GO:0048481,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050789,GO:0050794,GO:0061458,GO:0065007,GO:0071704,GO:0090304,GO:0090567,GO:0099402,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,ProRS-C_1,tRNA-synt_2b SJTD3_k127_4127474_1 1132442.KB889752_gene3016 1.778e-22 104.0 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZBKV@1386|Bacillus 91061|Bacilli L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Excalibur,HHH_3,LTD,Lactamase_B,SLH SJTD3_k127_4127474_0 526225.Gobs_2142 2.316e-125 418.0 COG3391@1|root,COG4995@1|root,COG3391@2|Bacteria,COG4995@2|Bacteria,2HF98@201174|Actinobacteria,4EWDJ@85013|Frankiales 201174|Actinobacteria S amine dehydrogenase activity - - - - - - - - - - - - - SJTD3_k127_4130430_1 525904.Tter_1359 1.104e-17 93.0 2EHA5@1|root,33B21@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - NERD SJTD3_k127_4130430_0 309801.trd_0002 6.546e-22 100.0 COG2812@1|root,COG2812@2|Bacteria,2G6K3@200795|Chloroflexi,27Y5T@189775|Thermomicrobia 189775|Thermomicrobia L DNA polymerase III, delta subunit - - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2 SJTD3_k127_4140320_3 240015.ACP_3495 4.289e-09 63.0 COG0845@1|root,COG0845@2|Bacteria,3Y77A@57723|Acidobacteria,2JMIR@204432|Acidobacteriia 204432|Acidobacteriia M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K15727 - - - - ko00000,ko02000 8.A.1.2.1 - - HlyD_D23 SJTD3_k127_4140320_0 272134.KB731326_gene273 1.966e-96 329.0 COG2132@1|root,COG2132@2|Bacteria,1G3J9@1117|Cyanobacteria 1117|Cyanobacteria Q Multicopper oxidase - - - - - - - - - - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 SJTD3_k127_4140320_1 383372.Rcas_3039 9.948e-39 162.0 COG1874@1|root,COG1874@2|Bacteria,2GBMG@200795|Chloroflexi,376H5@32061|Chloroflexia 32061|Chloroflexia G Flagellar filament outer layer protein Flaa - - - - - - - - - - - - Glyco_hydro_42,Glyco_hydro_cc SJTD3_k127_4140320_2 1268239.PALB_9460 7.255e-18 97.0 COG4805@1|root,COG4805@2|Bacteria,1MUBX@1224|Proteobacteria,1RMT7@1236|Gammaproteobacteria,2Q06Z@267888|Pseudoalteromonadaceae 1236|Gammaproteobacteria S protein conserved in bacteria - - - - - - - - - - - - DUF885 SJTD3_k127_4144519_1 525904.Tter_1066 1.399e-34 143.0 COG0668@1|root,COG0668@2|Bacteria,2NPVN@2323|unclassified Bacteria 2|Bacteria M Mechanosensitive ion channel - - - ko:K03442 - - - - ko00000,ko02000 1.A.23.2 - - MS_channel SJTD3_k127_4144519_0 485913.Krac_11186 1.382e-56 204.0 COG1057@1|root,COG1057@2|Bacteria,2G6MY@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD - 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like SJTD3_k127_4145408_1 1499967.BAYZ01000019_gene6297 1.028e-123 405.0 COG1609@1|root,COG1609@2|Bacteria,2NPGW@2323|unclassified Bacteria 2|Bacteria K PFAM Periplasmic binding protein LacI transcriptional regulator purR GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001216,GO:0001217,GO:0002054,GO:0002057,GO:0002060,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006140,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019220,GO:0019222,GO:0030808,GO:0030809,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0036094,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045936,GO:0045980,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0062014,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1900371,GO:1900372,GO:1900542,GO:1900543,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529,ko:K03604 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 SJTD3_k127_4145408_0 1303518.CCALI_01101 2.808e-171 553.0 COG1129@1|root,COG1129@2|Bacteria 2|Bacteria G ABC transporter rbsA - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_4145408_2 1499967.BAYZ01000119_gene3192 2.148e-76 266.0 COG1172@1|root,COG1172@2|Bacteria,2NPUE@2323|unclassified Bacteria 2|Bacteria U Branched-chain amino acid transport system / permease component - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_4149611_0 479434.Sthe_1621 0.0 1276.0 COG0178@1|root,COG0178@2|Bacteria,2G60U@200795|Chloroflexi,27XGQ@189775|Thermomicrobia 189775|Thermomicrobia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - - SJTD3_k127_4149611_2 485913.Krac_0968 2.744e-38 150.0 COG2318@1|root,COG2318@2|Bacteria,2G92D@200795|Chloroflexi 2|Bacteria S SPTR D1C1B9 DinB family protein dinB - - - - - - - - - - - DUF664,DinB SJTD3_k127_4149611_1 867845.KI911784_gene1050 4.826e-82 275.0 2CMS6@1|root,32SFE@2|Bacteria,2G905@200795|Chloroflexi,377IA@32061|Chloroflexia 32061|Chloroflexia S DinB superfamily - - - - - - - - - - - - DinB_2 SJTD3_k127_4151447_0 43989.cce_3762 8.041e-69 243.0 COG0500@1|root,COG2226@2|Bacteria,1G4ZW@1117|Cyanobacteria,3KJWU@43988|Cyanothece 1117|Cyanobacteria Q Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11,Methyltransf_31 SJTD3_k127_4151447_2 383372.Rcas_1618 6.113e-05 56.0 COG1287@1|root,COG1287@2|Bacteria,2GA82@200795|Chloroflexi,375J6@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - PMT_2 SJTD3_k127_4167719_5 867845.KI911784_gene2411 1.934e-21 104.0 COG2324@1|root,COG2324@2|Bacteria,2G7BI@200795|Chloroflexi,375RQ@32061|Chloroflexia 32061|Chloroflexia S Carotenoid biosynthesis protein - - - - - - - - - - - - Caroten_synth SJTD3_k127_4167719_3 309801.trd_1553 1.996e-34 136.0 COG0316@1|root,COG0316@2|Bacteria,2G705@200795|Chloroflexi,27YEW@189775|Thermomicrobia 189775|Thermomicrobia S Belongs to the HesB IscA family - - - ko:K13628 - - - - ko00000,ko03016 - - - Fe-S_biosyn SJTD3_k127_4167719_0 525904.Tter_1920 4.299e-121 413.0 COG0514@1|root,COG0514@2|Bacteria,2NNZU@2323|unclassified Bacteria 2|Bacteria L ATP-dependent DNA helicase RecQ recQ - 3.6.4.12 ko:K03654 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,DUF3553,HRDC,Helicase_C,RQC,RecQ_Zn_bind SJTD3_k127_4167719_4 326427.Cagg_1761 2.954e-32 142.0 COG1131@1|root,COG1131@2|Bacteria,2GAPH@200795|Chloroflexi,375EU@32061|Chloroflexia 32061|Chloroflexia V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_4167719_2 357808.RoseRS_2781 6.81e-46 172.0 COG0335@1|root,COG0335@2|Bacteria,2G6W0@200795|Chloroflexi,375NX@32061|Chloroflexia 32061|Chloroflexia J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 SJTD3_k127_4167719_1 1382306.JNIM01000001_gene3760 4.918e-48 180.0 COG0164@1|root,COG0164@2|Bacteria,2G6KR@200795|Chloroflexi 200795|Chloroflexi L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII SJTD3_k127_4168417_0 243164.DET1196 1.25e-150 520.0 COG0210@1|root,COG0210@2|Bacteria,2G5XF@200795|Chloroflexi,34D7Z@301297|Dehalococcoidia 301297|Dehalococcoidia L UvrD/REP helicase N-terminal domain pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C SJTD3_k127_4168417_3 1121272.KB903249_gene2255 2.668e-21 103.0 COG0778@1|root,COG0778@2|Bacteria,2HG9I@201174|Actinobacteria,4DK68@85008|Micromonosporales 201174|Actinobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase SJTD3_k127_4168417_2 1382356.JQMP01000003_gene1374 1.987e-40 163.0 COG2373@1|root,COG2373@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia 189775|Thermomicrobia P alginic acid biosynthetic process - - - - - - - - - - - - - SJTD3_k127_4168417_1 383372.Rcas_3030 1.448e-84 283.0 COG1506@1|root,COG1506@2|Bacteria,2G5NN@200795|Chloroflexi,3765E@32061|Chloroflexia 32061|Chloroflexia E peptidase S9 prolyl oligopeptidase active site domain protein - - - - - - - - - - - - PD40,Peptidase_S9 SJTD3_k127_4186180_2 1122915.AUGY01000017_gene2541 6.73e-148 476.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,4HDRR@91061|Bacilli,2764R@186822|Paenibacillaceae 91061|Bacilli G Periplasmic binding protein domain - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_4186180_4 324057.Pjdr2_5328 1.111e-135 440.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,26UGN@186822|Paenibacillaceae 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_4186180_0 333138.LQ50_02925 2.879e-200 636.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,1ZB07@1386|Bacillus 91061|Bacilli G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system mglA - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_4186180_6 926550.CLDAP_17910 3.515e-81 282.0 COG1609@1|root,COG1609@2|Bacteria,2G7NI@200795|Chloroflexi 200795|Chloroflexi K PFAM periplasmic binding protein LacI transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI SJTD3_k127_4186180_5 515635.Dtur_1708 4.132e-87 299.0 COG1609@1|root,COG1609@2|Bacteria 2|Bacteria K purine nucleotide biosynthetic process - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 SJTD3_k127_4186180_1 926550.CLDAP_17920 1.125e-173 552.0 COG0656@1|root,COG0656@2|Bacteria,2G6NH@200795|Chloroflexi 200795|Chloroflexi S Aldo/keto reductase family - - 1.1.1.2 ko:K00002 ko00010,ko00040,ko00561,ko00930,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00561,map00930,map01100,map01110,map01120,map01130,map01220 M00014 R00746,R01041,R01481,R05231 RC00087,RC00088,RC00099,RC00108 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Aldo_ket_red SJTD3_k127_4186180_3 935948.KE386495_gene1876 8.13e-136 459.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,42I3N@68295|Thermoanaerobacterales 186801|Clostridia G FGGY family of carbohydrate kinases, N-terminal domain - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N SJTD3_k127_4186180_7 1280698.AUJS01000016_gene1716 4.112e-75 264.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,27WHK@189330|Dorea 186801|Clostridia E Zinc-binding dehydrogenase - - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N SJTD3_k127_4186180_9 697303.Thewi_0215 2.125e-61 222.0 COG1105@1|root,COG1105@2|Bacteria,1TR9H@1239|Firmicutes,25CD6@186801|Clostridia,42G9V@68295|Thermoanaerobacterales 186801|Clostridia H Belongs to the carbohydrate kinase PfkB family. LacC subfamily lacC - 2.7.1.144,2.7.1.56 ko:K00882,ko:K00917 ko00051,ko00052,ko01100,map00051,map00052,map01100 - R02071,R03236 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB SJTD3_k127_4186180_10 383372.Rcas_2834 4.326e-46 169.0 COG4154@1|root,COG4154@2|Bacteria 2|Bacteria G fucose binding fucU - 5.1.3.29 ko:K02431 - - R10764 RC00563 ko00000,ko01000 - - - RbsD_FucU SJTD3_k127_4186180_8 324602.Caur_1070 3.697e-65 226.0 COG3684@1|root,COG3684@2|Bacteria,2G5XK@200795|Chloroflexi,376YA@32061|Chloroflexia 32061|Chloroflexia G PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase - - 4.1.2.40 ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 - R01069 RC00438,RC00439 ko00000,ko00001,ko01000 - - - DeoC SJTD3_k127_4190633_3 485913.Krac_4459 9.918e-17 85.0 COG2120@1|root,COG2120@2|Bacteria,2G6FB@200795|Chloroflexi 200795|Chloroflexi S PFAM LmbE family protein - - - - - - - - - - - - PIG-L SJTD3_k127_4190633_2 1382306.JNIM01000001_gene1880 1.104e-62 228.0 COG1078@1|root,COG1078@2|Bacteria 2|Bacteria S dGTPase activity ydhJ GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - ko:K06885 - - - - ko00000 - - - HD SJTD3_k127_4190633_1 397945.Aave_0958 4.16e-64 237.0 COG0438@1|root,COG0438@2|Bacteria,1MYJ6@1224|Proteobacteria 1224|Proteobacteria M Glycosyl transferase group 1 wbmJ - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_4190633_0 383372.Rcas_0764 1.498e-102 344.0 COG0367@1|root,COG0367@2|Bacteria,2G7R3@200795|Chloroflexi,37669@32061|Chloroflexia 32061|Chloroflexia F TIGRFAM asparagine synthase (glutamine-hydrolyzing) - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SJTD3_k127_4192219_2 383372.Rcas_2209 9.812e-81 277.0 COG0438@1|root,COG0438@2|Bacteria,2G5KS@200795|Chloroflexi,374UR@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - 2.4.1.250 ko:K15521 - - - - ko00000,ko01000 - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_4192219_3 926550.CLDAP_37610 5.411e-55 207.0 COG5653@1|root,COG5653@2|Bacteria,2G6Z0@200795|Chloroflexi 200795|Chloroflexi M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_6 SJTD3_k127_4192219_4 926560.KE387027_gene964 1.404e-48 181.0 COG5516@1|root,COG5516@2|Bacteria,1WMR5@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Putative stress-induced transcription regulator - - - - - - - - - - - - ABATE,zf-CGNR SJTD3_k127_4192219_0 316274.Haur_3502 4.878e-145 472.0 COG0206@1|root,COG0206@2|Bacteria,2G5V2@200795|Chloroflexi,374RU@32061|Chloroflexia 32061|Chloroflexia D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ - - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin SJTD3_k127_4192219_1 316274.Haur_3503 8.229e-124 413.0 COG0849@1|root,COG0849@2|Bacteria,2G5V5@200795|Chloroflexi,3757J@32061|Chloroflexia 32061|Chloroflexia D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA - - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - FtsA,SHS2_FTSA SJTD3_k127_4199298_4 292459.STH1400 2.473e-48 191.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia 186801|Clostridia HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 SJTD3_k127_4199298_3 1499967.BAYZ01000009_gene5348 6.574e-88 295.0 COG1428@1|root,COG1428@2|Bacteria,2NR23@2323|unclassified Bacteria 2|Bacteria F Deoxynucleoside kinase dck - - - - - - - - - - - dNK SJTD3_k127_4199298_5 1449126.JQKL01000073_gene3042 5.277e-34 134.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,268ZJ@186813|unclassified Clostridiales 186801|Clostridia F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 SJTD3_k127_4199298_1 383372.Rcas_0738 1.557e-110 372.0 COG1253@1|root,COG1253@2|Bacteria,2G6D1@200795|Chloroflexi,3752J@32061|Chloroflexia 32061|Chloroflexia S PFAM CBS domain containing protein - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 SJTD3_k127_4199298_0 324602.Caur_2197 4.163e-111 367.0 COG0462@1|root,COG0462@2|Bacteria,2G6AF@200795|Chloroflexi,374S5@32061|Chloroflexia 32061|Chloroflexia F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N SJTD3_k127_4199298_2 1128421.JAGA01000002_gene39 7.319e-99 335.0 COG1207@1|root,COG1207@2|Bacteria,2NNPC@2323|unclassified Bacteria 2|Bacteria M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042,ko:K11528,ko:K16203 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000,ko01002 3.A.1.5.2 - iJN678.glmU,iLJ478.TM1629 Hexapep,NTP_transf_3,NTP_transferase SJTD3_k127_4205012_1 316274.Haur_0363 3.072e-27 117.0 COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,3776W@32061|Chloroflexia 32061|Chloroflexia S PFAM DegV family protein - - - - - - - - - - - - DegV SJTD3_k127_4205012_0 479434.Sthe_1906 9.962e-180 586.0 COG1200@1|root,COG1200@2|Bacteria,2G5YM@200795|Chloroflexi,27XT4@189775|Thermomicrobia 189775|Thermomicrobia L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge SJTD3_k127_4207526_0 1382306.JNIM01000001_gene2493 1.161e-155 495.0 COG1012@1|root,COG1012@2|Bacteria,2G86D@200795|Chloroflexi 200795|Chloroflexi C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh SJTD3_k127_4207526_1 1499967.BAYZ01000184_gene4613 4.627e-36 142.0 COG0494@1|root,COG0494@2|Bacteria 2|Bacteria L nUDIX hydrolase - - 3.6.1.13,3.6.1.55 ko:K01515,ko:K03574 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000,ko03400 - - - NUDIX SJTD3_k127_4210480_0 1476973.JMMB01000007_gene1985 2.236e-184 595.0 COG0003@1|root,COG0003@2|Bacteria,1TQZP@1239|Firmicutes,249JN@186801|Clostridia,25T55@186804|Peptostreptococcaceae 186801|Clostridia D Anion-transporting ATPase arsA - 3.6.3.16 ko:K01551 - - - - ko00000,ko01000,ko02000 3.A.19.1,3.A.21.1,3.A.4.1 - - ArsA_ATPase SJTD3_k127_4210480_2 926569.ANT_00450 2.169e-49 183.0 COG0394@1|root,COG0394@2|Bacteria,2G6TY@200795|Chloroflexi 200795|Chloroflexi T Low molecular weight phosphotyrosine protein phosphatase arsC - 1.20.4.1 ko:K03741 - - - - ko00000,ko01000 - - - HTH_5,LMWPc SJTD3_k127_4210480_1 1379698.RBG1_1C00001G0821 2.927e-132 432.0 COG0798@1|root,COG0798@2|Bacteria,2NNWJ@2323|unclassified Bacteria 2|Bacteria P Sodium Bile acid symporter family arsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 ko:K03325,ko:K03741 - - - - ko00000,ko01000,ko02000 2.A.59 - iYO844.BSU25790 SBF SJTD3_k127_4210480_4 311424.DhcVS_111 2.108e-10 62.0 COG0243@1|root,COG0243@2|Bacteria,2G7RG@200795|Chloroflexi,34D80@301297|Dehalococcoidia 301297|Dehalococcoidia C Molybdopterin oxidoreductase Fe4S4 domain - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_4210480_3 546414.Deide_13360 6.383e-26 107.0 COG1028@1|root,COG1028@2|Bacteria,1WKYF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus IQ PFAM short chain dehydrogenase - - - - - - - - - - - - adh_short_C2 SJTD3_k127_4212514_5 8010.XP_010887507.1 0.0004876 49.0 COG0308@1|root,KOG1046@2759|Eukaryota,38CFG@33154|Opisthokonta,3BADC@33208|Metazoa,3CW5S@33213|Bilateria,486H0@7711|Chordata,48VUN@7742|Vertebrata,4A251@7898|Actinopterygii 33208|Metazoa O Aminopeptidase puromycin sensitive NPEPPS GO:0000003,GO:0000209,GO:0000578,GO:0000793,GO:0000922,GO:0001666,GO:0003002,GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0006464,GO:0006508,GO:0006518,GO:0006807,GO:0006950,GO:0007049,GO:0007275,GO:0007350,GO:0007351,GO:0007389,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008595,GO:0009056,GO:0009628,GO:0009790,GO:0009792,GO:0009798,GO:0009880,GO:0009948,GO:0009952,GO:0009987,GO:0010564,GO:0010720,GO:0015630,GO:0016567,GO:0016787,GO:0019538,GO:0022402,GO:0022414,GO:0030588,GO:0030590,GO:0032446,GO:0032501,GO:0032502,GO:0033218,GO:0033554,GO:0034641,GO:0035282,GO:0036211,GO:0036293,GO:0036294,GO:0042221,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043603,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044771,GO:0045595,GO:0045597,GO:0046662,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048856,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050896,GO:0051094,GO:0051179,GO:0051235,GO:0051239,GO:0051240,GO:0051321,GO:0051445,GO:0051640,GO:0051641,GO:0051642,GO:0051651,GO:0051657,GO:0051661,GO:0051716,GO:0051726,GO:0060281,GO:0060282,GO:0060284,GO:0061842,GO:0065007,GO:0065008,GO:0070006,GO:0070011,GO:0070482,GO:0070647,GO:0070887,GO:0071453,GO:0071456,GO:0071704,GO:0072686,GO:0097431,GO:0140096,GO:1900193,GO:1900195,GO:1901564,GO:1901565,GO:1901575,GO:1903046,GO:1903429,GO:1903431,GO:1903538,GO:1905879,GO:1905881,GO:1990947,GO:2000241,GO:2000243 - ko:K08776 - - - - ko00000,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 SJTD3_k127_4212514_1 1444309.JAQG01000065_gene2431 1.039e-98 332.0 COG3173@1|root,COG3173@2|Bacteria,1UIXX@1239|Firmicutes,4ISW9@91061|Bacilli,26VY7@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF1679) - - - - - - - - - - - - APH SJTD3_k127_4212514_0 479434.Sthe_1292 4.059e-114 375.0 COG0152@1|root,COG0152@2|Bacteria,2G6S5@200795|Chloroflexi,27Y59@189775|Thermomicrobia 189775|Thermomicrobia F SAICAR synthetase purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt SJTD3_k127_4212514_4 1382356.JQMP01000004_gene25 5.846e-19 96.0 COG1828@1|root,COG1828@2|Bacteria,2GBWK@200795|Chloroflexi,27YN2@189775|Thermomicrobia 189775|Thermomicrobia F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purS - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - PurS SJTD3_k127_4212514_2 156889.Mmc1_0691 6.103e-72 252.0 COG0489@1|root,COG0489@2|Bacteria,1MU7R@1224|Proteobacteria,2TRDM@28211|Alphaproteobacteria 28211|Alphaproteobacteria D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP mrp - - ko:K03593 - - - - ko00000,ko03029,ko03036 - - - FeS_assembly_P,ParA SJTD3_k127_4212514_3 1382356.JQMP01000004_gene24 1.395e-27 113.0 COG0047@1|root,COG0047@2|Bacteria,2G6R9@200795|Chloroflexi,27XM6@189775|Thermomicrobia 189775|Thermomicrobia F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purQ - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - GATase_5 SJTD3_k127_4221175_1 1382356.JQMP01000003_gene2345 1.527e-26 116.0 COG0287@1|root,COG0287@2|Bacteria,2G6BW@200795|Chloroflexi,27XQX@189775|Thermomicrobia 189775|Thermomicrobia C Prephenate dehydrogenase - - 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - - PDH SJTD3_k127_4221175_0 1380390.JIAT01000009_gene671 3.388e-101 353.0 COG0477@1|root,COG2814@2|Bacteria,2I2DZ@201174|Actinobacteria 201174|Actinobacteria EGP Major facilitator Superfamily - - - - - - - - - - - - MFS_1,Sugar_tr SJTD3_k127_4221175_4 994573.T472_0206195 0.0004922 52.0 COG4655@1|root,COG4655@2|Bacteria,1U3VZ@1239|Firmicutes,258W7@186801|Clostridia,36HTN@31979|Clostridiaceae 186801|Clostridia S Putative Flp pilus-assembly TadE/G-like - - - - - - - - - - - - Tad SJTD3_k127_4221175_2 596151.DesfrDRAFT_0994 5.986e-07 58.0 COG4961@1|root,COG4961@2|Bacteria,1NGEX@1224|Proteobacteria,42XRE@68525|delta/epsilon subdivisions,2WSQQ@28221|Deltaproteobacteria,2MCW5@213115|Desulfovibrionales 28221|Deltaproteobacteria U TadE-like protein - - - - - - - - - - - - TadE SJTD3_k127_4221175_3 309801.trd_A0617 4.541e-06 59.0 COG4961@1|root,COG4961@2|Bacteria,2GBBK@200795|Chloroflexi,27YP1@189775|Thermomicrobia 189775|Thermomicrobia U TadE-like protein - - - - - - - - - - - - TadE SJTD3_k127_4227383_1 1128421.JAGA01000002_gene1962 1.336e-142 460.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2NQDQ@2323|unclassified Bacteria 2|Bacteria P Rhodanese Homology Domain baeB - 3.1.2.6,3.4.21.102 ko:K01069,ko:K03797 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000,ko01002 - - - Lactamase_B,Rhodanese SJTD3_k127_4227383_0 644966.Tmar_1638 2.094e-177 563.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3WCWS@538999|Clostridiales incertae sedis 186801|Clostridia H Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate glpK GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 - R00847 RC00002,RC00017 ko00000,ko00001,ko01000,ko04147 - - - FGGY_C,FGGY_N SJTD3_k127_4232277_6 1123290.AUDQ01000022_gene745 0.000607 47.0 COG0791@1|root,COG0791@2|Bacteria,1V9FW@1239|Firmicutes,4HISN@91061|Bacilli,26FSP@186818|Planococcaceae 91061|Bacilli M S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_4232277_4 1145276.T479_08195 2.256e-15 89.0 COG2911@1|root,COG3209@1|root,COG4632@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG4632@2|Bacteria,1UK8Y@1239|Firmicutes 1239|Firmicutes M Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - - - - - - - - - - Big_4,Flg_new,LRR_5 SJTD3_k127_4232277_2 867845.KI911784_gene1169 9.129e-37 155.0 COG0738@1|root,COG0738@2|Bacteria 2|Bacteria G Major facilitator superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_4232277_1 926560.KE387023_gene2085 5.403e-59 220.0 COG0265@1|root,COG0265@2|Bacteria 2|Bacteria O serine-type endopeptidase activity - - - - - - - - - - - - PDZ_2,SIR2_2,Trypsin_2 SJTD3_k127_4232277_0 521045.Kole_1815 5.087e-90 303.0 COG2227@1|root,COG2227@2|Bacteria 2|Bacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity smtA - - ko:K06219 - - - - ko00000 - - - Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25 SJTD3_k127_4232277_3 1454004.AW11_01160 4.773e-27 116.0 COG1051@1|root,COG1051@2|Bacteria,1P6Z0@1224|Proteobacteria 1224|Proteobacteria F NUDIX domain - - - - - - - - - - - - NUDIX SJTD3_k127_4232277_5 1206744.BAGL01000044_gene1025 0.0001815 45.0 COG0346@1|root,COG0346@2|Bacteria,2IQUP@201174|Actinobacteria,4G1DP@85025|Nocardiaceae 201174|Actinobacteria E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - - - - - - - - - - Glyoxalase SJTD3_k127_4243304_0 479434.Sthe_0792 2.598e-94 323.0 COG0006@1|root,COG0006@2|Bacteria,2G6AE@200795|Chloroflexi,27XYM@189775|Thermomicrobia 189775|Thermomicrobia E Belongs to the peptidase M24B family - - 3.4.11.9 ko:K01262 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 SJTD3_k127_4243304_2 525904.Tter_1660 3.148e-68 236.0 COG0231@1|root,COG0231@2|Bacteria,2NPID@2323|unclassified Bacteria 2|Bacteria J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C SJTD3_k127_4243304_7 357808.RoseRS_3172 4.986e-36 144.0 COG0511@1|root,COG0511@2|Bacteria,2G94M@200795|Chloroflexi,375SP@32061|Chloroflexia 32061|Chloroflexia I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA - - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl SJTD3_k127_4243304_9 479434.Sthe_2018 6.969e-26 121.0 COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,27Y04@189775|Thermomicrobia 189775|Thermomicrobia S Lysylphosphatidylglycerol synthase TM region - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SJTD3_k127_4243304_1 926550.CLDAP_29920 8.885e-91 313.0 COG0438@1|root,COG0438@2|Bacteria,2G6I1@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4 SJTD3_k127_4243304_12 907931.AEIZ01000010_gene1412 0.0002693 50.0 COG4272@1|root,COG4272@2|Bacteria,1VGWJ@1239|Firmicutes,4HQ1Q@91061|Bacilli,4AY2Q@81850|Leuconostocaceae 91061|Bacilli S Protein of unknown function (DUF1634) - - - - - - - - - - - - DUF1634 SJTD3_k127_4243304_4 278957.ABEA03000006_gene4188 6.933e-53 199.0 COG0730@1|root,COG0730@2|Bacteria,46V52@74201|Verrucomicrobia,3K9AP@414999|Opitutae 414999|Opitutae S Sulfite exporter TauE/SafE - - - ko:K07090 - - - - ko00000 - - - TauE SJTD3_k127_4243304_10 1349767.GJA_2390 3.476e-17 90.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,2VHAZ@28216|Betaproteobacteria,4723Y@75682|Oxalobacteraceae 28216|Betaproteobacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease SJTD3_k127_4243304_3 1380370.JIBA01000002_gene2635 5.209e-53 200.0 COG2362@1|root,COG2362@2|Bacteria,2GK6A@201174|Actinobacteria 201174|Actinobacteria E D-aminopeptidase - - - ko:K16203 - - - - ko00000,ko01000,ko01002 3.A.1.5.2 - - Peptidase_M55 SJTD3_k127_4243304_11 742159.HMPREF0004_0979 1.104e-14 84.0 28JZA@1|root,2Z9PD@2|Bacteria,1N6W7@1224|Proteobacteria 1224|Proteobacteria S Domain of unknown function (DUF4261) - - - - - - - - - - - - DUF4261 SJTD3_k127_4243304_6 1382306.JNIM01000001_gene3809 3.941e-36 147.0 COG0500@1|root,COG2226@2|Bacteria,2G724@200795|Chloroflexi 200795|Chloroflexi Q Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SJTD3_k127_4243304_8 710243.XP_007590959.1 1.753e-26 117.0 29DCH@1|root,2RKGE@2759|Eukaryota,39VKP@33154|Opisthokonta,3P0RU@4751|Fungi,3QSIU@4890|Ascomycota,218IF@147550|Sordariomycetes,1ETTY@1028384|Glomerellales 4751|Fungi - - - - - - - - - - - - - - - SJTD3_k127_4251842_1 1382356.JQMP01000003_gene1933 4.021e-91 309.0 COG0533@1|root,COG0533@2|Bacteria,2G5V0@200795|Chloroflexi,27XRB@189775|Thermomicrobia 189775|Thermomicrobia J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD - 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 SJTD3_k127_4251842_2 479434.Sthe_0914 1.541e-54 204.0 COG0454@1|root,COG0456@2|Bacteria,2G6TF@200795|Chloroflexi,27Y7H@189775|Thermomicrobia 189775|Thermomicrobia K FR47-like protein - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1 SJTD3_k127_4251842_4 1128421.JAGA01000002_gene1896 1.5e-35 146.0 COG1214@1|root,COG1214@2|Bacteria,2NPK8@2323|unclassified Bacteria 2|Bacteria O Glycoprotease family yeaZ GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 SJTD3_k127_4251842_3 479434.Sthe_0912 3.055e-42 162.0 COG0802@1|root,COG0802@2|Bacteria,2G6YV@200795|Chloroflexi,27YBZ@189775|Thermomicrobia 189775|Thermomicrobia S Threonylcarbamoyl adenosine biosynthesis protein TsaE - - - ko:K06925 - - - - ko00000,ko03016 - - - TsaE SJTD3_k127_4251842_0 479434.Sthe_0904 5.621e-97 330.0 COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_4251842_8 1034769.KB910518_gene3650 4.346e-13 80.0 COG2314@1|root,COG2314@2|Bacteria,1U0XW@1239|Firmicutes,4IAE1@91061|Bacilli,272Q1@186822|Paenibacillaceae 91061|Bacilli S TM2 domain - - - - - - - - - - - - - SJTD3_k127_4251842_7 1382356.JQMP01000003_gene1396 9.804e-20 101.0 COG2373@1|root,COG3591@1|root,COG2373@2|Bacteria,COG3591@2|Bacteria 2|Bacteria E Belongs to the peptidase S1B family - - - ko:K13735 ko05100,map05100 - - - ko00000,ko00001 - - - Big_1,DUF3494,IAT_beta,Invasin_D3 SJTD3_k127_4251842_5 472759.Nhal_1774 1.096e-32 136.0 COG0500@1|root,COG2226@2|Bacteria,1RB5H@1224|Proteobacteria,1SYTI@1236|Gammaproteobacteria,1X2IR@135613|Chromatiales 135613|Chromatiales Q Ribosomal protein L11 methyltransferase (PrmA) - - 2.1.1.103 ko:K05929 ko00564,map00564 - R02037,R06868,R06869 RC00003,RC00060,RC00181,RC00496 ko00000,ko00001,ko01000 - - - Methyltransf_25 SJTD3_k127_4251842_6 591158.SSMG_03646 2.9e-21 99.0 COG1309@1|root,COG1309@2|Bacteria,2GJQY@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_N SJTD3_k127_4265328_1 45351.EDO38346 1.264e-93 319.0 COG0151@1|root,COG0299@1|root,KOG0237@2759|Eukaryota,KOG3076@2759|Eukaryota,38BPB@33154|Opisthokonta,3BDXA@33208|Metazoa 33208|Metazoa F Trifunctional purine biosynthetic protein GART GO:0001505,GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006544,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009069,GO:0009108,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0010033,GO:0010035,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042133,GO:0042221,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046112,GO:0046148,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.2,6.3.3.1,6.3.4.13 ko:K11787 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R04144,R04208,R04325,R04326 RC00026,RC00090,RC00166,RC00197,RC01100,RC01128 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C,Formyl_trans_N,GARS_A,GARS_C,GARS_N SJTD3_k127_4265328_2 1122939.ATUD01000003_gene3619 5.876e-29 131.0 COG5542@1|root,COG5542@2|Bacteria,2HNS4@201174|Actinobacteria,4CPZM@84995|Rubrobacteria 84995|Rubrobacteria S Mannosyltransferase (PIG-V) - - - - - - - - - - - - Mannosyl_trans2 SJTD3_k127_4265328_0 1128421.JAGA01000004_gene2673 4.089e-161 514.0 COG0519@1|root,COG0519@2|Bacteria,2NNRS@2323|unclassified Bacteria 2|Bacteria F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - iJN746.PP_1032,iSF_1195.SF2553,iSFxv_1172.SFxv_2808,iS_1188.S2725,iYL1228.KPN_02833 GATase,GMP_synt_C,NAD_synthase SJTD3_k127_4271656_0 316274.Haur_1576 4.816e-55 203.0 COG2267@1|root,COG2267@2|Bacteria 2|Bacteria I carboxylic ester hydrolase activity - - - - - - - - - - - - Abhydrolase_6,Hydrolase_4 SJTD3_k127_4271656_1 324602.Caur_1960 3.087e-24 109.0 COG0859@1|root,COG0859@2|Bacteria,2G6JB@200795|Chloroflexi,376CN@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase family 9 - - - ko:K02843 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SJTD3_k127_4274272_1 1303518.CCALI_00145 1.376e-57 209.0 COG0193@1|root,COG0193@2|Bacteria 2|Bacteria J aminoacyl-tRNA hydrolase activity pth GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro SJTD3_k127_4274272_0 1128421.JAGA01000004_gene2543 1.087e-284 910.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 2|Bacteria L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF SJTD3_k127_4285275_1 323098.Nwi_3040 3.327e-20 105.0 COG2114@1|root,COG3850@1|root,COG2114@2|Bacteria,COG3850@2|Bacteria,1QW6N@1224|Proteobacteria,2TWQ3@28211|Alphaproteobacteria,3JU8D@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - 4.6.1.1 ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 M00695 R00089,R00434 RC00295 ko00000,ko00001,ko00002,ko01000 - - - GAF,GAF_2,Guanylate_cyc,HAMP,dCache_1 SJTD3_k127_4285275_2 251221.35212600 2.148e-07 63.0 COG4244@1|root,COG4244@2|Bacteria,1G0PC@1117|Cyanobacteria 1117|Cyanobacteria S Membrane - - - - - - - - - - - - - SJTD3_k127_4285275_3 716544.wcw_1970 2.182e-05 49.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,2JFEX@204428|Chlamydiae 204428|Chlamydiae C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - - - - - - - - - - Fer4,Fer4_20,Pyr_redox_2 SJTD3_k127_4290815_1 235985.BBPN01000063_gene7498 4.691e-06 55.0 COG3511@1|root,COG4447@1|root,COG3511@2|Bacteria,COG4447@2|Bacteria,2IT8P@201174|Actinobacteria 201174|Actinobacteria M phospholipase C - - - - - - - - - - - - - SJTD3_k127_4290815_0 485913.Krac_12493 3.055e-114 376.0 COG0115@1|root,COG0115@2|Bacteria,2G5PM@200795|Chloroflexi 200795|Chloroflexi E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_4 SJTD3_k127_4290815_2 906888.JCM19314_32 1.555e-05 56.0 COG5658@1|root,COG5658@2|Bacteria,4NNCF@976|Bacteroidetes,1I1PF@117743|Flavobacteriia,3HKE3@363408|Nonlabens 976|Bacteroidetes S SdpI/YhfL protein family - - - - - - - - - - - - DUF1648,SdpI SJTD3_k127_4290815_3 1463881.KL591008_gene2092 0.0003986 51.0 COG4447@1|root,COG4447@2|Bacteria,2I4PF@201174|Actinobacteria 201174|Actinobacteria E Zinc metalloprotease (Elastase) - - - - - - - - - - - - Sortilin-Vps10 SJTD3_k127_4294469_0 1499968.TCA2_0732 2.608e-115 379.0 COG2421@1|root,COG2421@2|Bacteria,1TQ67@1239|Firmicutes,4HA9D@91061|Bacilli,26VMV@186822|Paenibacillaceae 91061|Bacilli C Acetamidase/Formamidase family - - - - - - - - - - - - FmdA_AmdA SJTD3_k127_4294469_1 595460.RRSWK_01968 5.509e-10 65.0 COG2020@1|root,COG2020@2|Bacteria,2J3WD@203682|Planctomycetes 203682|Planctomycetes O Phospholipid methyltransferase - - - - - - - - - - - - PEMT SJTD3_k127_4296613_1 1125699.HMPREF9194_01678 1.517e-06 61.0 COG1331@1|root,COG1331@2|Bacteria,2J5M5@203691|Spirochaetes 203691|Spirochaetes O Highly conserved protein containing a thioredoxin domain - - - - - - - - - - - - - SJTD3_k127_4296613_0 1303518.CCALI_01780 2.006e-67 250.0 COG0153@1|root,COG0153@2|Bacteria 2|Bacteria G galactokinase activity galK - 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg SJTD3_k127_4299689_2 357808.RoseRS_4618 2.029e-34 143.0 COG1668@1|root,COG1668@2|Bacteria,2G76A@200795|Chloroflexi,3777A@32061|Chloroflexia 32061|Chloroflexia CP ABC-2 family transporter protein - - - - - - - - - - - - ABC2_membrane_2 SJTD3_k127_4299689_0 357808.RoseRS_4617 8.537e-89 304.0 COG1131@1|root,COG1131@2|Bacteria,2G6HA@200795|Chloroflexi,376NC@32061|Chloroflexia 32061|Chloroflexia V PFAM ABC transporter related - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SJTD3_k127_4299689_1 309801.trd_1763 5.588e-41 173.0 COG2340@1|root,COG5479@1|root,COG2340@2|Bacteria,COG5479@2|Bacteria,2GBCS@200795|Chloroflexi,27YT2@189775|Thermomicrobia 189775|Thermomicrobia M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP SJTD3_k127_4299689_5 243265.plu3935 6.059e-13 82.0 COG3664@1|root,COG3664@2|Bacteria,1MWYX@1224|Proteobacteria,1S1VX@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Beta-xylosidase xynB - 3.2.1.37 ko:K01198,ko:K21000 ko00520,ko01100,ko02025,map00520,map01100,map02025 - R01433 RC00467 ko00000,ko00001,ko01000 - GH39,GH43 - Cellulase,Glyco_hydro_39,Glyco_hydro_42 SJTD3_k127_4299689_4 867903.ThesuDRAFT_00669 3.701e-18 92.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WDDX@538999|Clostridiales incertae sedis 186801|Clostridia L Helix-hairpin-helix motif comEA - - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB SJTD3_k127_4299689_3 316274.Haur_0179 1.66e-25 108.0 COG1842@1|root,COG1842@2|Bacteria,2G8QB@200795|Chloroflexi,375EJ@32061|Chloroflexia 32061|Chloroflexia KT PFAM PspA IM30 family protein - - - ko:K03969 - - - - ko00000 - - - PspA_IM30 SJTD3_k127_4306003_0 1382356.JQMP01000003_gene1531 5.485e-51 196.0 COG2340@1|root,COG5479@1|root,COG2340@2|Bacteria,COG5479@2|Bacteria,2GBCS@200795|Chloroflexi,27YT2@189775|Thermomicrobia 189775|Thermomicrobia M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP SJTD3_k127_4306003_1 1280692.AUJL01000001_gene48 2.5e-29 124.0 COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,36E39@31979|Clostridiaceae 186801|Clostridia P Acts as a magnesium transporter - - - ko:K06213 - - - - ko00000,ko02000 1.A.26.1 - - CBS,MgtE,MgtE_N,PRC SJTD3_k127_430815_1 1123023.JIAI01000010_gene8679 2.009e-18 88.0 COG2141@1|root,COG2141@2|Bacteria,2HVKH@201174|Actinobacteria,4EASP@85010|Pseudonocardiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_430815_0 395961.Cyan7425_3275 8.491e-123 424.0 COG5001@1|root,COG5001@2|Bacteria,1G0SY@1117|Cyanobacteria,3KGDE@43988|Cyanothece 1117|Cyanobacteria T PAS fold-4 domain protein - - - - - - - - - - - - EAL,GAF,GAF_2,GGDEF,PAS,PAS_3,PAS_4,PAS_9 SJTD3_k127_4310046_4 1128421.JAGA01000002_gene1580 1.103e-24 118.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - GT87,PMT_2 SJTD3_k127_4310046_5 1183438.GKIL_3078 3.627e-21 108.0 COG1807@1|root,COG1807@2|Bacteria,1GCPV@1117|Cyanobacteria 1117|Cyanobacteria M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_4310046_3 525904.Tter_1814 5.441e-33 135.0 COG0359@1|root,COG0359@2|Bacteria,2NPX4@2323|unclassified Bacteria 2|Bacteria J Binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N SJTD3_k127_4310046_0 479434.Sthe_1596 1.921e-183 583.0 COG0305@1|root,COG0305@2|Bacteria,2G64D@200795|Chloroflexi,27XKA@189775|Thermomicrobia 189775|Thermomicrobia L Participates in initiation and elongation during chromosome replication - - 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C SJTD3_k127_4310046_2 357808.RoseRS_1148 1.984e-49 188.0 COG3935@1|root,COG3935@2|Bacteria,2G6W5@200795|Chloroflexi,3765A@32061|Chloroflexia 32061|Chloroflexia L TIGRFAM primosome, DnaD subunit - - - - - - - - - - - - DnaB_2 SJTD3_k127_4310046_1 479434.Sthe_1598 5.702e-80 278.0 COG1484@1|root,COG1484@2|Bacteria,2G65F@200795|Chloroflexi,27YCI@189775|Thermomicrobia 189775|Thermomicrobia L Bacterial dnaA protein - - - ko:K02315 - - - - ko00000,ko03032 - - - IstB_IS21 SJTD3_k127_4310046_6 326427.Cagg_2338 1.376e-09 63.0 COG0457@1|root,COG0457@2|Bacteria,2G73P@200795|Chloroflexi,374UJ@32061|Chloroflexia 32061|Chloroflexia S SMART Tetratricopeptide domain protein - - - - - - - - - - - - TPR_16,TPR_19,TPR_4,TPR_6,TPR_7,TPR_8 SJTD3_k127_4311509_0 671143.DAMO_0449 8.822e-77 276.0 COG1572@1|root,COG1572@2|Bacteria 2|Bacteria NU bacterial-type flagellum-dependent cell motility - - - - - - - - - - - - DUF11,DUF3367,DUF5122,HemolysinCabind,NPCBM SJTD3_k127_4311509_1 1125863.JAFN01000001_gene1410 1.267e-26 115.0 COG0824@1|root,COG0824@2|Bacteria,1MZTU@1224|Proteobacteria,42WZM@68525|delta/epsilon subdivisions,2WT0J@28221|Deltaproteobacteria 28221|Deltaproteobacteria S Thioesterase-like superfamily - - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 SJTD3_k127_4311509_2 525904.Tter_0001 8.409e-06 48.0 COG0593@1|root,COG0593@2|Bacteria,2NNTK@2323|unclassified Bacteria 2|Bacteria L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N SJTD3_k127_4318581_1 350688.Clos_1058 7.65e-08 62.0 COG0421@1|root,COG0421@2|Bacteria,1VRGK@1239|Firmicutes,24C37@186801|Clostridia,36RCA@31979|Clostridiaceae 186801|Clostridia E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - - - - - - - - - - Spermine_synth SJTD3_k127_4318581_0 340.xcc-b100_2506 5.837e-16 92.0 COG0657@1|root,COG0657@2|Bacteria,1QDQP@1224|Proteobacteria,1RQJR@1236|Gammaproteobacteria,1X5SS@135614|Xanthomonadales 135614|Xanthomonadales I Glycosyl hydrolase family 65, N-terminal domain - - 3.2.1.51 ko:K15923 ko00511,map00511 - - - ko00000,ko00001,ko01000 - GH95 - Glyco_hyd_65N_2 SJTD3_k127_4320684_2 203119.Cthe_0901 9.198e-67 232.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,3WHX6@541000|Ruminococcaceae 186801|Clostridia H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC - 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase SJTD3_k127_4320684_0 479434.Sthe_0650 7.248e-120 398.0 COG0372@1|root,COG0372@2|Bacteria,2G637@200795|Chloroflexi,27Y5Z@189775|Thermomicrobia 200795|Chloroflexi C Citrate synthase, C-terminal domain - - 2.3.3.1,2.3.3.5 ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351,R00931 RC00004,RC00067,RC00406,RC02827 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt SJTD3_k127_4320684_1 941449.dsx2_2100 4.23e-84 289.0 COG0413@1|root,COG0413@2|Bacteria,1MU3B@1224|Proteobacteria,42MES@68525|delta/epsilon subdivisions,2WIQK@28221|Deltaproteobacteria,2M8WY@213115|Desulfovibrionales 28221|Deltaproteobacteria H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate panB - 2.1.2.11 ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R01226 RC00022,RC00200 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_transf SJTD3_k127_4320684_3 479434.Sthe_0697 3.554e-36 143.0 COG5495@1|root,COG5495@2|Bacteria,2G6F3@200795|Chloroflexi,27YA4@189775|Thermomicrobia 189775|Thermomicrobia S Rossmann-like domain - - - - - - - - - - - - DUF2520,Rossmann-like SJTD3_k127_4329363_10 1262915.BN574_00167 3.665e-13 72.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4H2EW@909932|Negativicutes 909932|Negativicutes J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB SJTD3_k127_4329363_4 1463909.KL585966_gene449 3.017e-47 175.0 COG3576@1|root,COG3576@2|Bacteria 2|Bacteria S Pyridoxamine 5'-phosphate oxidase - - - ko:K07006 - - - - ko00000 - - - Putative_PNPOx SJTD3_k127_4329363_9 981369.JQMJ01000003_gene7088 2.159e-20 97.0 COG3467@1|root,COG3467@2|Bacteria,2GSII@201174|Actinobacteria,2NIMB@228398|Streptacidiphilus 201174|Actinobacteria S Pyridoxamine 5'-phosphate oxidase - - - - - - - - - - - - Putative_PNPOx SJTD3_k127_4329363_1 1128421.JAGA01000002_gene155 1.767e-75 268.0 COG0601@1|root,COG0601@2|Bacteria 2|Bacteria P nitrogen compound transport appB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 SJTD3_k127_4329363_3 525904.Tter_0815 1.11e-67 243.0 COG0122@1|root,COG0122@2|Bacteria,2NRQK@2323|unclassified Bacteria 2|Bacteria L endonuclease III alkA - 4.2.99.18 ko:K03660 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - HhH-GPD,OGG_N SJTD3_k127_4329363_0 926550.CLDAP_20620 1.01e-84 287.0 COG1435@1|root,COG1435@2|Bacteria,2G6DP@200795|Chloroflexi 200795|Chloroflexi F PFAM thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK SJTD3_k127_4329363_8 525904.Tter_0490 2.686e-25 109.0 COG0254@1|root,COG0254@2|Bacteria,2NPUV@2323|unclassified Bacteria 2|Bacteria J Binds the 23S rRNA rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 SJTD3_k127_4329363_6 768706.Desor_5066 4.743e-31 126.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,262E4@186807|Peptococcaceae 186801|Clostridia J Belongs to the bacterial ribosomal protein bL27 family rpmA - - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 SJTD3_k127_4329363_5 1382356.JQMP01000003_gene1853 2.696e-32 128.0 COG0261@1|root,COG0261@2|Bacteria,2G72T@200795|Chloroflexi,27YJB@189775|Thermomicrobia 189775|Thermomicrobia J This protein binds to 23S rRNA in the presence of protein L20 rplU - - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p SJTD3_k127_4329363_7 1120746.CCNL01000008_gene609 2.155e-27 125.0 COG1879@1|root,COG1879@2|Bacteria 2|Bacteria G ABC-type sugar transport system periplasmic component - - - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_4329363_2 357808.RoseRS_3659 1.267e-73 272.0 COG0515@1|root,COG0515@2|Bacteria,2GBWC@200795|Chloroflexi,375DM@32061|Chloroflexia 32061|Chloroflexia KLT Serine threonine protein kinase - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - Pkinase SJTD3_k127_4330346_3 402777.KB235908_gene131 2.261e-18 97.0 COG0749@1|root,COG0749@2|Bacteria,1G4PE@1117|Cyanobacteria,1HE6C@1150|Oscillatoriales 1117|Cyanobacteria L DNA polymerase A domain - - 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - DNA_pol_A,DNA_pol_A_exo1 SJTD3_k127_4330346_1 1382306.JNIM01000001_gene4139 7.968e-102 347.0 COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi 200795|Chloroflexi K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released rpoD - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SJTD3_k127_4330346_4 314345.SPV1_07346 8.444e-17 93.0 COG0348@1|root,COG0348@2|Bacteria,1MUWD@1224|Proteobacteria 1224|Proteobacteria C 4Fe-4S binding domain - - - - - - - - - - - - Fer4_18,Fer4_5 SJTD3_k127_4330346_5 1089439.KB902253_gene1414 0.0006651 43.0 COG5563@1|root,COG5563@2|Bacteria 2|Bacteria - - CP_1076 - - ko:K21449 - - - - ko00000,ko02000 1.B.40.2 - - Autotransporter,DUF1929,Glyoxal_oxid_N,PA14 SJTD3_k127_4330346_2 717606.PaecuDRAFT_3213 1.855e-73 256.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli,26QCB@186822|Paenibacillaceae 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase SJTD3_k127_4330346_0 1280390.CBQR020000164_gene4346 1.383e-121 398.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,4HA2G@91061|Bacilli,26R1I@186822|Paenibacillaceae 91061|Bacilli IQ PFAM AMP-dependent synthetase and ligase lcfA - 6.2.1.3 ko:K01897,ko:K18661 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280,R03383 RC00004,RC00014,RC00137 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C SJTD3_k127_4345290_3 1292034.OR37_00230 8.409e-07 59.0 COG0859@1|root,COG0859@2|Bacteria,1PV11@1224|Proteobacteria,2U3V4@28211|Alphaproteobacteria 28211|Alphaproteobacteria M COG0859 ADP-heptose LPS heptosyltransferase - - - - - - - - - - - - Glyco_transf_9 SJTD3_k127_4345290_0 485913.Krac_11292 4.858e-96 327.0 COG0859@1|root,COG0859@2|Bacteria,2G8F3@200795|Chloroflexi 200795|Chloroflexi M Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 SJTD3_k127_4345290_2 1173027.Mic7113_3502 1.329e-19 103.0 COG3675@1|root,COG3675@2|Bacteria 2|Bacteria I Lipase (class 3) - - - - - - - - - - - - DUF2974,LTD,Lipase_3 SJTD3_k127_4345290_1 511051.CSE_11690 4.102e-58 214.0 COG1173@1|root,COG1173@2|Bacteria 2|Bacteria P ABC-type dipeptide oligopeptide nickel transport systems, permease components appC - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N SJTD3_k127_4354675_0 309801.trd_A0813 8.898e-107 361.0 COG0457@1|root,COG0457@2|Bacteria,2G770@200795|Chloroflexi,27Y28@189775|Thermomicrobia 189775|Thermomicrobia S Domain of unknown function (DUF4388) - - - - - - - - - - - - DUF4388 SJTD3_k127_4354675_1 1286093.C266_23281 1.995e-07 58.0 COG1396@1|root,COG1396@2|Bacteria,1NGM7@1224|Proteobacteria,2VW3W@28216|Betaproteobacteria,1KAV3@119060|Burkholderiaceae 28216|Betaproteobacteria K TRANSCRIPTIONal - - - - - - - - - - - - HTH_3 SJTD3_k127_4354675_2 867845.KI911784_gene1158 1.05e-06 61.0 COG1807@1|root,COG1807@2|Bacteria,2GBNV@200795|Chloroflexi,37833@32061|Chloroflexia 32061|Chloroflexia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - SJTD3_k127_4357208_0 1227453.C444_18487 5.265e-05 51.0 arCOG06174@1|root,arCOG06174@2157|Archaea,2XTF2@28890|Euryarchaeota,23UDI@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - SJTD3_k127_4357208_1 1185653.A1A1_07002 0.0002089 49.0 COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,4HDUN@91061|Bacilli,26EQ5@186818|Planococcaceae 91061|Bacilli S Belongs to the SOS response-associated peptidase family yoqW - - - - - - - - - - - SRAP SJTD3_k127_4375604_1 1214101.BN159_3431 2.917e-32 133.0 COG1309@1|root,COG1309@2|Bacteria,2I9IJ@201174|Actinobacteria 201174|Actinobacteria K Bacterial transcriptional repressor C-terminal - - - - - - - - - - - - TetR_C_11,TetR_N SJTD3_k127_4375604_3 586416.GZ22_10080 6.01e-07 61.0 COG1511@1|root,COG1511@2|Bacteria,1TSD6@1239|Firmicutes,4HBWZ@91061|Bacilli 91061|Bacilli V membrane - - - - - - - - - - - - ABC2_membrane_3,DUF3533 SJTD3_k127_4375604_2 1068980.ARVW01000001_gene6240 8.647e-17 95.0 COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4E2Z7@85010|Pseudonocardiales 201174|Actinobacteria C Copper binding proteins, plastocyanin/azurin family - - - - - - - - - - - - Copper-bind,Cupredoxin_1 SJTD3_k127_4375604_0 479434.Sthe_1693 1.058e-139 468.0 COG3693@1|root,COG5479@1|root,COG3693@2|Bacteria,COG5479@2|Bacteria,2GBGU@200795|Chloroflexi,27Y52@189775|Thermomicrobia 200795|Chloroflexi M Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase SJTD3_k127_4381057_0 316274.Haur_0684 5.148e-169 548.0 COG1132@1|root,COG1132@2|Bacteria,2G5QH@200795|Chloroflexi,375CH@32061|Chloroflexia 32061|Chloroflexia V PFAM ABC transporter transmembrane region - - - ko:K11085 ko02010,map02010 - - - ko00000,ko00001,ko01000,ko02000 3.A.1.106 - - ABC_membrane,ABC_tran SJTD3_k127_4400113_5 1111131.HMPREF1255_1275 1.065e-22 106.0 COG2259@1|root,COG2259@2|Bacteria,2IQEY@201174|Actinobacteria 201174|Actinobacteria O DoxX family - - - - - - - - - - - - DoxX,MauE SJTD3_k127_4400113_2 635013.TherJR_2709 2.066e-76 264.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,260CH@186807|Peptococcaceae 186801|Clostridia G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA - 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM SJTD3_k127_4400113_0 479434.Sthe_0903 2.708e-312 987.0 COG4581@1|root,COG4581@2|Bacteria,2G7P6@200795|Chloroflexi,27XJ5@189775|Thermomicrobia 189775|Thermomicrobia L DSHCT - - - ko:K03727 - - - - ko00000,ko01000 - - - DEAD,DSHCT,Helicase_C SJTD3_k127_4400113_3 1003195.SCAT_2747 9.2e-34 141.0 COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria 201174|Actinobacteria Q Methyltransferase type 11 - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_4400113_1 1382306.JNIM01000001_gene587 6.684e-100 336.0 COG1237@1|root,COG1237@2|Bacteria,2G73K@200795|Chloroflexi 200795|Chloroflexi S Metallo-beta-lactamase superfamily - - 2.5.1.105 ko:K06897 ko00790,map00790 - R10339 RC00121 ko00000,ko00001,ko01000 - - - Lactamase_B SJTD3_k127_4400113_4 351160.RCIX535 3.027e-24 103.0 COG4832@1|root,arCOG03201@2157|Archaea,2Y3NU@28890|Euryarchaeota 28890|Euryarchaeota S GyrI-like small molecule binding domain - - - - - - - - - - - - GyrI-like SJTD3_k127_4408357_7 1449126.JQKL01000025_gene2389 4.708e-25 109.0 COG0011@1|root,COG0011@2|Bacteria,1VAIR@1239|Firmicutes,24NBA@186801|Clostridia 186801|Clostridia S TIGRFAM Protein of - - - - - - - - - - - - Thiamine_BP SJTD3_k127_4408357_0 1128421.JAGA01000002_gene1735 1.843e-192 611.0 COG0439@1|root,COG0439@2|Bacteria,2NNWM@2323|unclassified Bacteria 2|Bacteria I acetyl-CoA carboxylase, biotin carboxylase accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 SJTD3_k127_4408357_10 316274.Haur_0750 1.522e-17 86.0 COG1302@1|root,COG1302@2|Bacteria,2G7GB@200795|Chloroflexi 200795|Chloroflexi S Asp23 family, cell envelope-related function - - - - - - - - - - - - Asp23 SJTD3_k127_4408357_6 485913.Krac_8246 1.561e-36 144.0 COG0781@1|root,COG0781@2|Bacteria,2G6XA@200795|Chloroflexi 200795|Chloroflexi K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB SJTD3_k127_4408357_13 1499967.BAYZ01000055_gene4865 8.984e-08 57.0 COG0236@1|root,COG0236@2|Bacteria,2NPVJ@2323|unclassified Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding SJTD3_k127_4408357_12 1123230.ARQJ01000033_gene1761 3.965e-09 63.0 COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,4HNQ0@91061|Bacilli,4GZNZ@90964|Staphylococcaceae 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding SJTD3_k127_4408357_4 525904.Tter_1640 7.887e-54 199.0 COG0805@1|root,COG0805@2|Bacteria,2NPGB@2323|unclassified Bacteria 2|Bacteria U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC SJTD3_k127_4408357_1 383372.Rcas_4287 1.932e-110 380.0 COG1293@1|root,COG1293@2|Bacteria,2G5TC@200795|Chloroflexi,375AD@32061|Chloroflexia 32061|Chloroflexia K Fibronectin-binding A domain protein - - - - - - - - - - - - DUF814,FbpA SJTD3_k127_4408357_2 316274.Haur_0619 1.516e-59 215.0 COG0194@1|root,COG0194@2|Bacteria,2G6EW@200795|Chloroflexi,375HJ@32061|Chloroflexia 32061|Chloroflexia F Essential for recycling GMP and indirectly, cGMP gmk - 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Guanylate_kin SJTD3_k127_4408357_11 383372.Rcas_1639 2.458e-15 89.0 COG0457@1|root,COG0457@2|Bacteria,2GB8I@200795|Chloroflexi,377JS@32061|Chloroflexia 32061|Chloroflexia S Tetratricopeptide repeat - - - - - - - - - - - - - SJTD3_k127_4408357_5 33898.JRHJ01000069_gene7008 2.584e-53 196.0 COG2129@1|root,COG2129@2|Bacteria,2GJ72@201174|Actinobacteria 201174|Actinobacteria S metallophosphoesterase - - - - - - - - - - - - Metallophos SJTD3_k127_4408357_9 479434.Sthe_1592 2.55e-19 90.0 COG2331@1|root,COG2331@2|Bacteria,2G752@200795|Chloroflexi,27YP8@189775|Thermomicrobia 189775|Thermomicrobia S Putative regulatory protein - - - - - - - - - - - - Zn-ribbon_8 SJTD3_k127_4408357_3 926550.CLDAP_28750 2.281e-57 209.0 COG0566@1|root,COG0566@2|Bacteria,2G6FR@200795|Chloroflexi 200795|Chloroflexi J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family - - 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind SJTD3_k127_4408357_8 1382356.JQMP01000004_gene207 2.274e-24 107.0 COG4911@1|root,COG4911@2|Bacteria,2G7A8@200795|Chloroflexi,27YIV@189775|Thermomicrobia 189775|Thermomicrobia S Uncharacterized conserved protein (DUF2203) - - - - - - - - - - - - DUF2203 SJTD3_k127_4413712_0 1408427.JADB01000010_gene1470 9.771e-09 65.0 COG1388@1|root,COG4942@1|root,COG1388@2|Bacteria,COG4942@2|Bacteria,1RD24@1224|Proteobacteria,2TUNI@28211|Alphaproteobacteria,48TR1@772|Bartonellaceae 28211|Alphaproteobacteria DM Lysin motif nlpD - - ko:K06194 - - - - ko00000 1.A.34.1.2 - - LysM,Peptidase_M23 SJTD3_k127_4413712_1 378806.STAUR_6728 1.965e-08 66.0 COG1388@1|root,COG3179@1|root,COG1388@2|Bacteria,COG3179@2|Bacteria,1MYUR@1224|Proteobacteria,42UGP@68525|delta/epsilon subdivisions,2WWB8@28221|Deltaproteobacteria,2YZ5E@29|Myxococcales 28221|Deltaproteobacteria M Chitinase class I - - - ko:K03791 - - - - ko00000 - GH19 - Glyco_hydro_19,LysM,PG_binding_1 SJTD3_k127_4420513_2 479434.Sthe_0322 2.096e-66 234.0 COG0012@1|root,COG0012@2|Bacteria,2G5UY@200795|Chloroflexi,27XGT@189775|Thermomicrobia 189775|Thermomicrobia J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF - - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C SJTD3_k127_4420513_1 1382356.JQMP01000003_gene2596 1.395e-108 380.0 COG2720@1|root,COG2720@2|Bacteria,2G67R@200795|Chloroflexi,27XP7@189775|Thermomicrobia 189775|Thermomicrobia V VanW like protein - - - - - - - - - - - - PG_binding_4,VanW SJTD3_k127_4420513_0 204669.Acid345_1786 7.07e-156 520.0 COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria,2JHQ9@204432|Acidobacteriia 204432|Acidobacteriia C Dehydrogenase E1 component - - 1.2.4.4 ko:K11381 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 M00036 R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997 RC00027,RC00627,RC02743,RC02883,RC02949,RC02953 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh,Transket_pyr,Transketolase_C SJTD3_k127_4436087_1 522306.CAP2UW1_0994 0.0002405 44.0 COG3743@1|root,COG3743@2|Bacteria,1RA3K@1224|Proteobacteria,2VVIG@28216|Betaproteobacteria 28216|Betaproteobacteria S Domain of unknown function (DUF4332) - - - - - - - - - - - - DUF4332 SJTD3_k127_4436087_0 479434.Sthe_2325 6.378e-107 360.0 COG0451@1|root,COG0451@2|Bacteria,2G9SG@200795|Chloroflexi 200795|Chloroflexi GM PFAM NAD-dependent epimerase dehydratase - - - - - - - - - - - - Epimerase SJTD3_k127_4454974_0 861299.J421_5949 1.205e-60 231.0 COG0515@1|root,COG0515@2|Bacteria 861299.J421_5949|- KLT protein kinase activity - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - - SJTD3_k127_4455991_1 525904.Tter_1257 1.867e-42 164.0 COG1842@1|root,COG1842@2|Bacteria,2NR8F@2323|unclassified Bacteria 2|Bacteria KT PspA/IM30 family pspA GO:0003674,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0008289,GO:0009266,GO:0009271,GO:0009408,GO:0009605,GO:0009607,GO:0009615,GO:0009628,GO:0009889,GO:0009898,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0031323,GO:0031326,GO:0042802,GO:0043167,GO:0043168,GO:0043207,GO:0043433,GO:0044092,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0050896,GO:0051090,GO:0051171,GO:0051252,GO:0051704,GO:0051707,GO:0060187,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:0080090,GO:0098552,GO:0098562,GO:0098586,GO:1903506,GO:2000112,GO:2001141 3.1.21.3,5.4.99.13 ko:K01153,ko:K03615,ko:K03969,ko:K11942,ko:K15842 ko05120,map05120 M00564 - - ko00000,ko00001,ko00002,ko01000,ko02048 - - - LRAT,PspA_IM30 SJTD3_k127_4455991_0 243231.GSU1083 1.448e-100 339.0 COG4260@1|root,COG4260@2|Bacteria,1MXTD@1224|Proteobacteria,42P7D@68525|delta/epsilon subdivisions,2WJ6S@28221|Deltaproteobacteria,43UZT@69541|Desulfuromonadales 28221|Deltaproteobacteria S SPFH domain-Band 7 family - - - - - - - - - - - - Band_7_1,DUF4339,DZR,SHOCT,zinc_ribbon_2 SJTD3_k127_4455991_3 1031711.RSPO_c00646 0.0006572 52.0 COG1105@1|root,COG1105@2|Bacteria,1MVNW@1224|Proteobacteria,2VPIP@28216|Betaproteobacteria,1KFS2@119060|Burkholderiaceae 28216|Betaproteobacteria H Belongs to the carbohydrate kinase PfkB family fruK - 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB SJTD3_k127_4456953_0 172088.AUGA01000006_gene8149 5.203e-311 961.0 COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,1MUTY@1224|Proteobacteria,2TQVU@28211|Alphaproteobacteria,3JRTU@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 SJTD3_k127_4456953_1 1297865.APJD01000012_gene1322 2.37e-10 72.0 COG0410@1|root,COG0410@2|Bacteria,1MUR3@1224|Proteobacteria,2TSWQ@28211|Alphaproteobacteria,3JRHZ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran SJTD3_k127_4460759_0 485913.Krac_6715 1.123e-199 639.0 COG1449@1|root,COG1449@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 57 family amyA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 ko:K22451 ko00500,map00500 - R05196 RC00049 ko00000,ko00001,ko01000 - GH57 - DUF1925,DUF1926,Glyco_hydro_57 SJTD3_k127_4462255_0 479434.Sthe_1152 1.057e-32 134.0 COG2244@1|root,COG2244@2|Bacteria,2G6CM@200795|Chloroflexi,27XXP@189775|Thermomicrobia 189775|Thermomicrobia S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C SJTD3_k127_4472832_1 720554.Clocl_2597 8.452e-81 280.0 COG2199@1|root,COG3903@1|root,COG3706@2|Bacteria,COG3903@2|Bacteria,1UZIV@1239|Firmicutes,24EXP@186801|Clostridia,3WI6E@541000|Ruminococcaceae 186801|Clostridia T NB-ARC domain - - - - - - - - - - - - GGDEF,NB-ARC,TPR_12 SJTD3_k127_4472832_0 1128421.JAGA01000004_gene2499 7.556e-111 379.0 COG0747@1|root,COG0747@2|Bacteria 2|Bacteria E dipeptide transport - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SJTD3_k127_4472832_3 338963.Pcar_2416 2.871e-14 87.0 COG1714@1|root,COG1714@2|Bacteria,1RJRV@1224|Proteobacteria,43B7D@68525|delta/epsilon subdivisions,2X6KS@28221|Deltaproteobacteria,43SMC@69541|Desulfuromonadales 28221|Deltaproteobacteria S RDD family - - - - - - - - - - - - RDD SJTD3_k127_4472832_4 1185876.BN8_04456 3.041e-11 70.0 COG1051@1|root,COG1051@2|Bacteria,4NN73@976|Bacteroidetes,47P7Y@768503|Cytophagia 976|Bacteroidetes F Nudix hydrolase - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX SJTD3_k127_4472832_2 485913.Krac_10618 2.396e-60 211.0 COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi 200795|Chloroflexi F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK SJTD3_k127_4473304_1 101510.RHA1_ro02716 7.004e-90 322.0 COG0515@1|root,COG2197@1|root,COG3903@1|root,COG0515@2|Bacteria,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae 201174|Actinobacteria K activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - AAA_22,GerE,NB-ARC,Pkinase,TPR_12,TPR_7 SJTD3_k127_4473304_4 927677.ALVU02000001_gene1427 9.352e-09 64.0 COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,1G135@1117|Cyanobacteria,1H4T7@1142|Synechocystis 1117|Cyanobacteria S CHAT domain - - - - - - - - - - - - CHAT,TPR_10,TPR_12,TPR_2,TPR_7,TPR_8 SJTD3_k127_4473304_2 67352.JODS01000001_gene476 8.214e-89 319.0 COG1572@1|root,COG1572@2|Bacteria,2GKNI@201174|Actinobacteria 201174|Actinobacteria Q Domain of unknown function (DUF5122) beta-propeller - - - - - - - - - - - - DUF11,DUF5122,HemolysinCabind SJTD3_k127_4473304_3 1132442.KB889752_gene3016 1.795e-18 100.0 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZBKV@1386|Bacillus 91061|Bacilli L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Excalibur,HHH_3,LTD,Lactamase_B,SLH SJTD3_k127_4473304_0 649831.L083_4978 7.744e-110 367.0 COG0246@1|root,COG0246@2|Bacteria,2GJ4F@201174|Actinobacteria,4DAEC@85008|Micromonosporales 201174|Actinobacteria G Mannitol dehydrogenase C-terminal domain mtlK - 1.1.1.57,1.1.1.67 ko:K00040,ko:K00045 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00061 R00868,R02454 RC00085 ko00000,ko00001,ko00002,ko01000 - - - Mannitol_dh,Mannitol_dh_C SJTD3_k127_4487568_2 485913.Krac_2318 2.584e-117 390.0 COG4987@1|root,COG4987@2|Bacteria,2GA7U@200795|Chloroflexi 200795|Chloroflexi V TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC - - - ko:K16012 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran SJTD3_k127_4487568_1 926550.CLDAP_15250 4.758e-145 472.0 COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase SJTD3_k127_4487568_0 1173024.KI912149_gene4937 1.409e-167 533.0 COG0033@1|root,COG0033@2|Bacteria,1G4TU@1117|Cyanobacteria 1117|Cyanobacteria G phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - iJN678.pgm PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SJTD3_k127_4489030_0 525904.Tter_2130 2.158e-105 351.0 COG2971@1|root,COG2971@2|Bacteria 2|Bacteria G N-acetylglucosamine kinase activity - - - - - - - - - - - - BcrAD_BadFG SJTD3_k127_4489030_1 525904.Tter_2131 3.998e-63 221.0 COG0363@1|root,COG0363@2|Bacteria,2NPPJ@2323|unclassified Bacteria 2|Bacteria G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB - 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso SJTD3_k127_4491634_1 1521187.JPIM01000091_gene3515 1.175e-37 156.0 COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia 32061|Chloroflexia S von Willebrand factor, type A - - - - - - - - - - - - BatA,VWA_2 SJTD3_k127_4491634_0 383372.Rcas_1972 3.459e-111 387.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2GAC2@200795|Chloroflexi,3754A@32061|Chloroflexia 32061|Chloroflexia S PFAM von Willebrand factor type A - - - - - - - - - - - - GATase1_like,VWA,VWA_3 SJTD3_k127_4492695_0 1089548.KI783301_gene809 9.933e-169 559.0 COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TRE5@1239|Firmicutes,4IUDA@91061|Bacilli 91061|Bacilli V FtsX-like permease family - - - - - - - - - - - - - SJTD3_k127_4492695_1 926569.ANT_27060 2.775e-89 300.0 COG1136@1|root,COG1136@2|Bacteria,2G69N@200795|Chloroflexi 200795|Chloroflexi P Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_4492695_2 1089548.KI783301_gene806 1.552e-48 180.0 COG1695@1|root,COG1695@2|Bacteria,1V6TJ@1239|Firmicutes,4HN21@91061|Bacilli,3WG5C@539002|Bacillales incertae sedis 91061|Bacilli K Transcriptional regulator PadR-like family padR - - - - - - - - - - - PadR,Vir_act_alpha_C SJTD3_k127_4492695_3 446470.Snas_5055 6.551e-21 93.0 COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4F0CB@85014|Glycomycetales 201174|Actinobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase SJTD3_k127_4495031_0 479434.Sthe_1027 4.047e-94 317.0 COG0452@1|root,COG0452@2|Bacteria,2G60D@200795|Chloroflexi,27XWG@189775|Thermomicrobia 189775|Thermomicrobia H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine - - 4.1.1.36,6.3.2.5 ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein SJTD3_k127_4495031_1 1122222.AXWR01000026_gene1657 6.387e-84 285.0 COG1521@1|root,COG1521@2|Bacteria,1WI0G@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase SJTD3_k127_4495031_2 383372.Rcas_0333 1.347e-60 213.0 COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,374TX@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase SJTD3_k127_4519362_0 1048339.KB913029_gene1857 1.103e-59 216.0 COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4ESAG@85013|Frankiales 201174|Actinobacteria S MMPL family - - - ko:K06994,ko:K20470 - - - - ko00000,ko02000 2.A.6.5.6 - - MMPL SJTD3_k127_4519362_4 1121441.AUCX01000036_gene21 2.702e-12 75.0 COG1309@1|root,COG1309@2|Bacteria,1R4IA@1224|Proteobacteria,43AT3@68525|delta/epsilon subdivisions,2X67G@28221|Deltaproteobacteria,2MD93@213115|Desulfovibrionales 28221|Deltaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N SJTD3_k127_4519362_1 536227.CcarbDRAFT_2229 2.961e-53 198.0 COG0657@1|root,COG0657@2|Bacteria,1UFB9@1239|Firmicutes,24DFS@186801|Clostridia,36HTV@31979|Clostridiaceae 186801|Clostridia I Dienelactone hydrolase family - - - - - - - - - - - - DLH SJTD3_k127_4519362_2 1869.MB27_33250 3.228e-21 106.0 2B84N@1|root,321CU@2|Bacteria,2H5C3@201174|Actinobacteria,4DJ4P@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_4519362_5 1521187.JPIM01000031_gene2002 2.244e-05 56.0 COG1376@1|root,COG1376@2|Bacteria,2G6ZY@200795|Chloroflexi,376UR@32061|Chloroflexia 32061|Chloroflexia M PFAM ErfK YbiS YcfS YnhG family protein - - - - - - - - - - - - YkuD SJTD3_k127_4519362_3 443144.GM21_1895 8.987e-17 93.0 COG3485@1|root,COG3485@2|Bacteria 2|Bacteria Q protocatechuate 3,4-dioxygenase activity catA - 1.13.11.1 ko:K03381 ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220 M00568 R00817,R04258,R05299,R08114,R08115,R09134 RC00388,RC00535,RC01366 ko00000,ko00001,ko00002,ko01000 - - - Dioxygenase_C SJTD3_k127_4540420_0 316274.Haur_4763 7.198e-123 408.0 COG3831@1|root,COG3831@2|Bacteria 2|Bacteria - - - - 2.4.2.30 ko:K10798 ko03410,ko04210,ko04212,ko04214,ko04217,map03410,map04210,map04212,map04214,map04217 M00296 - - ko00000,ko00001,ko00002,ko01000,ko03032,ko03036,ko03400 - - - DUF4240,PARP,WGR SJTD3_k127_454332_2 1499967.BAYZ01000026_gene1592 2.332e-09 61.0 COG0500@1|root,COG2226@2|Bacteria,2NRJH@2323|unclassified Bacteria 2|Bacteria Q Methyltransferase domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25 SJTD3_k127_454332_1 765420.OSCT_1723 4.121e-85 290.0 COG2141@1|root,COG2141@2|Bacteria,2G8PY@200795|Chloroflexi 200795|Chloroflexi C COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_454332_0 525904.Tter_1852 1.979e-235 743.0 COG1154@1|root,COG1154@2|Bacteria,2NNNA@2323|unclassified Bacteria 2|Bacteria H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) dxs GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0008661,GO:0009058,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901363,GO:1901576,GO:1901681 2.2.1.7 ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 M00096 R05636 RC00032 ko00000,ko00001,ko00002,ko01000 - - - DXP_synthase_N,Transket_pyr,Transketolase_C SJTD3_k127_4563282_0 452637.Oter_1105 2.249e-181 578.0 COG0366@1|root,COG0366@2|Bacteria,46S7A@74201|Verrucomicrobia 74201|Verrucomicrobia G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 SJTD3_k127_4563282_2 383372.Rcas_1159 0.0001183 55.0 COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi,375FV@32061|Chloroflexia 32061|Chloroflexia U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - SJTD3_k127_4563282_1 1347368.HG964403_gene3974 4.134e-28 123.0 COG4632@1|root,COG4632@2|Bacteria,1UWXQ@1239|Firmicutes,4HWZ4@91061|Bacilli,1ZNWY@1386|Bacillus 91061|Bacilli G S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_4563369_2 502025.Hoch_2462 2.25e-41 156.0 COG0346@1|root,COG0346@2|Bacteria,1RCGK@1224|Proteobacteria,43375@68525|delta/epsilon subdivisions,2WYIM@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Glyoxalase-like domain - - - - - - - - - - - - Glyoxalase SJTD3_k127_4563369_1 526227.Mesil_1024 4.31e-59 209.0 COG5646@1|root,COG5646@2|Bacteria,1WKCV@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S InterPro IPR014922 - - - - - - - - - - - - DUF1801 SJTD3_k127_4563369_3 1169161.KB897734_gene434 4.685e-07 54.0 COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria 201174|Actinobacteria S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 SJTD3_k127_4563369_0 1128421.JAGA01000002_gene774 6.491e-245 771.0 COG1164@1|root,COG1164@2|Bacteria,2NNUU@2323|unclassified Bacteria 2|Bacteria E Oligopeptidase F pepF - - - - - - - - - - - Peptidase_M3,Peptidase_M3_N SJTD3_k127_4564230_3 208444.JNYY01000004_gene2089 4.754e-05 45.0 COG0596@1|root,COG0596@2|Bacteria,2I32Y@201174|Actinobacteria,4EF89@85010|Pseudonocardiales 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_4564230_1 479432.Sros_4134 1.898e-74 259.0 COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4EJ5F@85012|Streptosporangiales 201174|Actinobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_4564230_2 485913.Krac_6654 1.696e-62 222.0 COG0262@1|root,COG0262@2|Bacteria 2|Bacteria H dihydrofolate reductase activity - - - - - - - - - - - - RibD_C SJTD3_k127_4564230_0 479435.Kfla_5828 8.765e-95 317.0 COG0596@1|root,COG0596@2|Bacteria,2I32Y@201174|Actinobacteria,4DWFD@85009|Propionibacteriales 201174|Actinobacteria S Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_4564230_4 926564.KI911740_gene3378 0.0002187 46.0 COG0662@1|root,COG0662@2|Bacteria,2GPQF@201174|Actinobacteria 201174|Actinobacteria G AraC-like ligand binding domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_4565453_0 479434.Sthe_0323 2.663e-122 423.0 COG4485@1|root,COG4485@2|Bacteria,2G75F@200795|Chloroflexi,27XT2@189775|Thermomicrobia 189775|Thermomicrobia S Bacterial membrane protein YfhO - - - - - - - - - - - - YfhO SJTD3_k127_4567953_1 479434.Sthe_1716 1.535e-48 176.0 COG1260@1|root,COG1260@2|Bacteria,2G5YH@200795|Chloroflexi,27Y0U@189775|Thermomicrobia 189775|Thermomicrobia I Myo-inositol-1-phosphate synthase - - 5.5.1.4 ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 - R07324 RC01804 ko00000,ko00001,ko01000 - - - Inos-1-P_synth SJTD3_k127_4567953_0 1382306.JNIM01000001_gene4124 2.111e-52 199.0 COG1560@1|root,COG1560@2|Bacteria 2|Bacteria M Kdo2-lipid A biosynthetic process - - 2.3.1.241,2.3.1.265 ko:K02517,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans SJTD3_k127_456916_15 1120950.KB892751_gene6788 1.731e-11 67.0 COG4608@1|root,COG4608@2|Bacteria,2IBD7@201174|Actinobacteria,4DTRV@85009|Propionibacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY SJTD3_k127_456916_1 926569.ANT_05610 0.0 1036.0 COG3250@1|root,COG3250@2|Bacteria,2G5R6@200795|Chloroflexi 200795|Chloroflexi G glycoside hydrolase family 2 sugar binding - - 3.2.1.25 ko:K01192 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Glyco_hydro_2 SJTD3_k127_456916_0 926550.CLDAP_09520 0.0 1048.0 COG1472@1|root,COG1472@2|Bacteria,2G5S5@200795|Chloroflexi 200795|Chloroflexi G Fibronectin type III-like domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C SJTD3_k127_456916_2 926550.CLDAP_00330 1.549e-223 700.0 COG2723@1|root,COG2723@2|Bacteria,2G67P@200795|Chloroflexi 200795|Chloroflexi G PFAM glycoside hydrolase, family 1 - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 SJTD3_k127_456916_12 869210.Marky_1956 4.55e-37 154.0 COG1073@1|root,COG1073@2|Bacteria,1WKS0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Prolyl oligopeptidase family - - - ko:K06889 - - - - ko00000 - - - Hydrolase_4,Peptidase_S9 SJTD3_k127_456916_9 309801.trd_0653 7.187e-59 218.0 COG1560@1|root,COG1560@2|Bacteria,2G7BA@200795|Chloroflexi,27Y7M@189775|Thermomicrobia 189775|Thermomicrobia M Bacterial lipid A biosynthesis acyltransferase - - 2.3.1.241,2.3.1.265 ko:K02517,ko:K22311 ko00540,ko01100,map00540,map01100 M00060 R05146 RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01005 - - - Lip_A_acyltrans SJTD3_k127_456916_4 309801.trd_1267 1.284e-108 370.0 COG1030@1|root,COG1030@2|Bacteria,2G6E2@200795|Chloroflexi,27XU8@189775|Thermomicrobia 189775|Thermomicrobia O NfeD-like C-terminal, partner-binding - - - ko:K07403 - - - - ko00000 - - - NfeD SJTD3_k127_456916_5 316274.Haur_1478 3.235e-104 349.0 COG0330@1|root,COG0330@2|Bacteria,2G5SB@200795|Chloroflexi,375BD@32061|Chloroflexia 32061|Chloroflexia O PFAM band 7 protein - - - - - - - - - - - - Band_7 SJTD3_k127_456916_11 324602.Caur_1063 6.356e-39 157.0 COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi,377CQ@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function (DUF541) - - - ko:K09807 - - - - ko00000 - - - SIMPL SJTD3_k127_456916_3 105422.BBPM01000102_gene5262 1.957e-155 515.0 COG3055@1|root,COG3405@1|root,COG3055@2|Bacteria,COG3405@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - ASH SJTD3_k127_456916_8 589924.Ferp_1932 3.039e-62 230.0 COG0477@1|root,arCOG00130@2157|Archaea,2XSTP@28890|Euryarchaeota 28890|Euryarchaeota G COG0477 Permeases of the major facilitator superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_456916_10 485913.Krac_8887 5.847e-50 186.0 COG3548@1|root,COG3548@2|Bacteria 2|Bacteria S protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - - - - - - - - - - DUF1211 SJTD3_k127_456916_6 1382356.JQMP01000003_gene1935 2.295e-92 315.0 COG0123@1|root,COG0123@2|Bacteria,2G5X3@200795|Chloroflexi,27XTE@189775|Thermomicrobia 189775|Thermomicrobia BQ Histone deacetylase domain - - - - - - - - - - - - Hist_deacetyl SJTD3_k127_456916_14 1521187.JPIM01000046_gene1486 6.405e-24 115.0 COG1196@1|root,COG1196@2|Bacteria,2G9QF@200795|Chloroflexi,37590@32061|Chloroflexia 32061|Chloroflexia D nuclear chromosome segregation - - - - - - - - - - - - - SJTD3_k127_456916_7 552811.Dehly_1512 1.576e-78 271.0 COG0030@1|root,COG0030@2|Bacteria,2G6ER@200795|Chloroflexi,34CIF@301297|Dehalococcoidia 301297|Dehalococcoidia J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA - 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD SJTD3_k127_456916_13 585423.KR49_03015 1.212e-36 143.0 COG1947@1|root,COG1947@2|Bacteria,1G0YY@1117|Cyanobacteria,1GZVI@1129|Synechococcus 1117|Cyanobacteria F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol ispE GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05634 RC00002,RC01439 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N SJTD3_k127_4586333_1 1034769.KB910518_gene1428 1.658e-36 143.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli,26T31@186822|Paenibacillaceae 91061|Bacilli J asparaginyl-tRNA synthetase asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon SJTD3_k127_4586333_0 216816.GS08_09605 3.356e-83 289.0 COG0167@1|root,COG0167@2|Bacteria,2GJMN@201174|Actinobacteria,4CZKM@85004|Bifidobacteriales 201174|Actinobacteria F Dihydroorotate dehydrogenase pyr - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh SJTD3_k127_459430_0 479434.Sthe_0301 1.105e-117 396.0 COG1007@1|root,COG1007@2|Bacteria,2G5ZK@200795|Chloroflexi,27XVQ@189775|Thermomicrobia 189775|Thermomicrobia C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoN - 1.6.5.3 ko:K00343 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_M SJTD3_k127_459430_1 316056.RPC_2416 9.107e-41 156.0 COG1008@1|root,COG1008@2|Bacteria,1MV7V@1224|Proteobacteria,2TSNK@28211|Alphaproteobacteria,3JTNA@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria C NADH-ubiquinone oxidoreductase chain 4, amino terminus nuoM GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 ko:K00342 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q5_N,Proton_antipo_M SJTD3_k127_4599916_1 867903.ThesuDRAFT_01380 1.119e-95 321.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia 186801|Clostridia P Belongs to the ABC transporter superfamily - - - ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY SJTD3_k127_4599916_0 1128421.JAGA01000002_gene157 2.652e-142 461.0 COG0444@1|root,COG0444@2|Bacteria,2NR32@2323|unclassified Bacteria 2|Bacteria P Oligopeptide/dipeptide transporter, C-terminal region oppD - - ko:K02031,ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY SJTD3_k127_46159_2 68170.KL590490_gene1161 4.827e-25 108.0 2E9P6@1|root,333VK@2|Bacteria,2IRX3@201174|Actinobacteria,4E5HS@85010|Pseudonocardiales 201174|Actinobacteria S SPW repeat - - - - - - - - - - - - SPW SJTD3_k127_46159_3 247156.NFA_50730 2.375e-20 99.0 COG1309@1|root,COG1309@2|Bacteria,2IRTT@201174|Actinobacteria,4FVAT@85025|Nocardiaceae 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - TetR_N SJTD3_k127_46159_0 485913.Krac_2351 6.643e-144 465.0 COG0053@1|root,COG0053@2|Bacteria,2G5MK@200795|Chloroflexi 200795|Chloroflexi P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - - - - - - - - - - Cation_efflux,ZT_dimer SJTD3_k127_46159_4 290340.AAur_pTC20013 1.101e-05 53.0 COG3832@1|root,COG3832@2|Bacteria,2GVS1@201174|Actinobacteria 201174|Actinobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 SJTD3_k127_46159_1 309801.trd_1637 2.997e-46 176.0 COG0308@1|root,COG0308@2|Bacteria,2G6SD@200795|Chloroflexi,27XPY@189775|Thermomicrobia 189775|Thermomicrobia E Peptidase MA superfamily - - - - - - - - - - - - Peptidase_MA_2 SJTD3_k127_4616526_1 497964.CfE428DRAFT_0785 6.173e-61 237.0 2BWCM@1|root,2ZKMD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_4616526_3 1206737.BAGF01000067_gene4190 2.142e-05 58.0 COG3386@1|root,COG3386@2|Bacteria,2I9Q3@201174|Actinobacteria,4G0W0@85025|Nocardiaceae 201174|Actinobacteria G PFAM SMP-30 Gluconolaconase - - - - - - - - - - - - SGL SJTD3_k127_4616526_2 497964.CfE428DRAFT_0785 1.578e-60 226.0 2BWCM@1|root,2ZKMD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_4616526_0 1121468.AUBR01000064_gene947 7.451e-71 242.0 COG0365@1|root,COG0365@2|Bacteria,1TQTI@1239|Firmicutes,24E00@186801|Clostridia,42FQ1@68295|Thermoanaerobacterales 186801|Clostridia I Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA - - 6.2.1.1 ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 M00357 R00235,R00236,R00316,R00926,R01354 RC00004,RC00012,RC00043,RC00070,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACAS_N,AMP-binding,AMP-binding_C SJTD3_k127_4616623_1 644966.Tmar_1592 1.886e-26 114.0 COG0607@1|root,COG0607@2|Bacteria 2|Bacteria P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - - - - - - - - - - DUF5069,Lactamase_B,Rhodanese SJTD3_k127_4616623_0 344747.PM8797T_10089 1.046e-118 389.0 COG1082@1|root,COG1082@2|Bacteria,2IY42@203682|Planctomycetes 203682|Planctomycetes G Xylose isomerase-like TIM barrel - - - - - - - - - - - - AP_endonuc_2 SJTD3_k127_461905_0 1382304.JNIL01000001_gene3204 2.633e-84 284.0 COG2041@1|root,COG2041@2|Bacteria,1V1P9@1239|Firmicutes,4HFQC@91061|Bacilli,278B0@186823|Alicyclobacillaceae 91061|Bacilli S Oxidoreductase molybdopterin binding domain yuiH - - - - - - - - - - - Oxidored_molyb SJTD3_k127_461905_1 1128421.JAGA01000003_gene3512 4.621e-41 166.0 COG0860@1|root,COG0860@2|Bacteria 2|Bacteria M N-Acetylmuramoyl-L-alanine amidase - GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3 SJTD3_k127_4639865_3 326427.Cagg_1710 2.593e-15 79.0 COG1193@1|root,COG1193@2|Bacteria,2G5R8@200795|Chloroflexi,3754B@32061|Chloroflexia 32061|Chloroflexia L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 - - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_III,MutS_V,Smr SJTD3_k127_4639865_1 525904.Tter_1099 1.828e-48 190.0 COG2856@1|root,COG2856@2|Bacteria,2NQY0@2323|unclassified Bacteria 2|Bacteria E Zn peptidase - - - - - - - - - - - - - SJTD3_k127_4639865_4 1121403.AUCV01000037_gene4268 2.803e-09 70.0 COG0457@1|root,COG0697@1|root,COG0457@2|Bacteria,COG0697@2|Bacteria 2|Bacteria EG spore germination - - - ko:K16928 - M00582 - - ko00000,ko00002,ko02000 3.A.1.33 - - DUF2723,QueT SJTD3_k127_4639865_2 1173023.KE650771_gene5511 5.862e-43 165.0 COG0662@1|root,COG0662@2|Bacteria,1GFZG@1117|Cyanobacteria 1117|Cyanobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_4639865_0 479434.Sthe_0796 5.921e-309 958.0 COG0556@1|root,COG0556@2|Bacteria,2G5SU@200795|Chloroflexi,27XME@189775|Thermomicrobia 189775|Thermomicrobia L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB SJTD3_k127_4701751_0 1521187.JPIM01000069_gene594 7.221e-36 148.0 COG0539@1|root,COG0539@2|Bacteria,2G656@200795|Chloroflexi,3757Z@32061|Chloroflexia 32061|Chloroflexia J PFAM RNA binding S1 domain protein - - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 SJTD3_k127_4704506_2 926569.ANT_19710 6.787e-77 262.0 COG0572@1|root,COG0572@2|Bacteria,2G6D5@200795|Chloroflexi 200795|Chloroflexi F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK SJTD3_k127_4704506_0 383372.Rcas_1998 6.049e-188 599.0 COG0366@1|root,COG3280@1|root,COG0366@2|Bacteria,COG3280@2|Bacteria,2G64W@200795|Chloroflexi,376K5@32061|Chloroflexia 32061|Chloroflexia G SMART alpha amylase, catalytic sub domain - - 3.2.1.133,3.2.1.135,3.2.1.54 ko:K01208 ko00500,ko01100,map00500,map01100 - R02112,R03122,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,Malt_amylase_C SJTD3_k127_4704506_1 316057.RPD_3346 2.469e-89 309.0 COG1568@1|root,COG1568@2|Bacteria 2|Bacteria S polyamine biosynthetic process speH - 2.5.1.128 ko:K07057 - - - - ko00000,ko01000 - - - DUF43 SJTD3_k127_4704506_3 211114.JOEF01000001_gene7196 4.339e-10 66.0 COG1247@1|root,COG1247@2|Bacteria,2GQ72@201174|Actinobacteria,4ECDG@85010|Pseudonocardiales 201174|Actinobacteria M Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_470538_1 1382356.JQMP01000004_gene653 1.073e-50 197.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_470538_2 1304874.JAFY01000002_gene336 2.507e-37 146.0 COG0251@1|root,COG0251@2|Bacteria 2|Bacteria J oxidation-reduction process - - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP SJTD3_k127_470538_0 357808.RoseRS_3025 3.394e-56 207.0 COG0265@1|root,COG0265@2|Bacteria,2G6KV@200795|Chloroflexi,375DX@32061|Chloroflexia 32061|Chloroflexia O PFAM peptidase S1 and S6, chymotrypsin Hap - - 1.3.1.74 ko:K08070 - - - - ko00000,ko01000 - - - PDZ_2,Trypsin_2 SJTD3_k127_4706506_0 1388763.O165_022595 1.117e-88 303.0 COG1109@1|root,COG1109@2|Bacteria,1MUA5@1224|Proteobacteria,1RMU8@1236|Gammaproteobacteria,1YXIY@136845|Pseudomonas putida group 1236|Gammaproteobacteria G phosphoglucomutase phosphomannomutase alpha beta alpha domain I algC GO:0003674,GO:0003824,GO:0004615,GO:0005975,GO:0008150,GO:0008152,GO:0016853,GO:0016866,GO:0016868,GO:0044238,GO:0071704 5.4.2.2,5.4.2.8 ko:K15778 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00114 R00959,R01057,R01818,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SJTD3_k127_4706506_4 684949.ATTJ01000002_gene106 6.336e-23 105.0 2ECKJ@1|root,33KDJ@2|Bacteria,1WMG2@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - DinB_2 SJTD3_k127_4706506_2 926560.KE387025_gene4131 2.873e-64 231.0 COG1028@1|root,COG1028@2|Bacteria,1WM2Z@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short SJTD3_k127_4706506_1 543728.Vapar_6005 3.591e-79 277.0 COG3191@1|root,COG3191@2|Bacteria 2|Bacteria EQ aminopeptidase activity - - - - - - - - - - - - Peptidase_S58 SJTD3_k127_4706506_5 429009.Adeg_1695 2.181e-10 63.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,42FBT@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS - 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b SJTD3_k127_4725891_5 1151126.AQYI01000002_gene198 1.137e-34 136.0 COG2020@1|root,COG2020@2|Bacteria,2IN0C@201174|Actinobacteria,4FKDA@85023|Microbacteriaceae 201174|Actinobacteria O Phospholipid methyltransferase - - - - - - - - - - - - PEMT SJTD3_k127_4725891_0 316274.Haur_3441 2.211e-127 424.0 COG0486@1|root,COG0486@2|Bacteria,2G647@200795|Chloroflexi,3751D@32061|Chloroflexia 32061|Chloroflexia J Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N SJTD3_k127_4725891_3 525904.Tter_1424 5.113e-57 209.0 COG0524@1|root,COG0524@2|Bacteria,2NRAA@2323|unclassified Bacteria 2|Bacteria G pfkB family carbohydrate kinase - - 2.7.1.3 ko:K00846 ko00051,ko01100,ko01120,map00051,map01100,map01120 - R00866,R03819 RC00002,RC00017,RC00608 ko00000,ko00001,ko01000,ko04147 - - - PfkB,Rieske SJTD3_k127_4725891_6 479434.Sthe_0167 1.578e-32 139.0 COG1847@1|root,COG1847@2|Bacteria,2G6XH@200795|Chloroflexi,27XWI@189775|Thermomicrobia 189775|Thermomicrobia S Putative single-stranded nucleic acids-binding domain - - - ko:K06346 - - - - ko00000 - - - Jag_N,R3H SJTD3_k127_4725891_4 479434.Sthe_0166 5.255e-53 201.0 COG0706@1|root,COG0706@2|Bacteria,2G6N0@200795|Chloroflexi,27XWD@189775|Thermomicrobia 189775|Thermomicrobia U PFAM 60 kDa inner membrane insertion protein - - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP SJTD3_k127_4725891_7 926569.ANT_22920 2.812e-28 116.0 COG0759@1|root,COG0759@2|Bacteria,2G76Q@200795|Chloroflexi 200795|Chloroflexi S Could be involved in insertion of integral membrane proteins into the membrane - - - ko:K08998 - - - - ko00000 - - - Haemolytic SJTD3_k127_4725891_8 383372.Rcas_1424 4e-25 111.0 COG0594@1|root,COG0594@2|Bacteria,2G76W@200795|Chloroflexi,375ZH@32061|Chloroflexia 32061|Chloroflexia J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA - 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P SJTD3_k127_4725891_9 479434.Sthe_0163 8.583e-17 81.0 COG0230@1|root,COG0230@2|Bacteria,2G7BX@200795|Chloroflexi,27YQV@189775|Thermomicrobia 189775|Thermomicrobia J Belongs to the bacterial ribosomal protein bL34 family rpmH - - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 SJTD3_k127_4725891_1 525904.Tter_0425 3.28e-122 402.0 COG0627@1|root,COG0627@2|Bacteria,2NQQ3@2323|unclassified Bacteria 2|Bacteria S Putative esterase - - - - - - - - - - - - Esterase SJTD3_k127_4725891_10 861299.J421_0508 2.939e-11 65.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis - - - - - - - - - - - - AhpC-TSA,NHL,Thioredoxin_8 SJTD3_k127_4725891_2 756272.Plabr_0401 1.869e-69 243.0 COG0526@1|root,COG3391@1|root,COG0526@2|Bacteria,COG3391@2|Bacteria,2IXWV@203682|Planctomycetes 203682|Planctomycetes CO PFAM NHL repeat - - - - - - - - - - - - NHL,Thioredoxin_8 SJTD3_k127_473239_1 1123278.KB893427_gene1235 1.436e-13 76.0 2AQ5P@1|root,31FB4@2|Bacteria,4NRIU@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SJTD3_k127_473239_0 42256.RradSPS_2897 1.205e-123 403.0 COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,4CRYS@84995|Rubrobacteria 84995|Rubrobacteria S VIT family - - - - - - - - - - - - VIT1 SJTD3_k127_4736334_5 526227.Mesil_2849 6.197e-46 182.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,1WM3F@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA_3,PAS_4,PAS_8 SJTD3_k127_4736334_4 485913.Krac_6834 5.185e-98 332.0 COG1175@1|root,COG1175@2|Bacteria,2G6P7@200795|Chloroflexi 200795|Chloroflexi P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K05814 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - BPD_transp_1 SJTD3_k127_4736334_3 485913.Krac_6835 2.461e-99 332.0 COG0395@1|root,COG0395@2|Bacteria,2G6H2@200795|Chloroflexi 200795|Chloroflexi P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02026,ko:K05815 ko02010,map02010 M00198,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.3 - - BPD_transp_1 SJTD3_k127_4736334_1 485913.Krac_6836 4.613e-136 455.0 COG1653@1|root,COG1653@2|Bacteria,2G6V5@200795|Chloroflexi 200795|Chloroflexi G extracellular solute-binding protein, family 1 - - - ko:K05813 ko02010,map02010 M00198 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.3 - - SBP_bac_8 SJTD3_k127_4736334_7 357808.RoseRS_3426 5.824e-21 94.0 2E90H@1|root,3339X@2|Bacteria,2GB2F@200795|Chloroflexi,377SX@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_4736334_6 357808.RoseRS_3425 3.875e-26 109.0 2C1SS@1|root,32YN6@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_4736334_2 37919.EP51_28130 2.582e-126 432.0 COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae 201174|Actinobacteria K activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - - - - - - - - - - AAA_22,GerE,NB-ARC,Pkinase,TPR_12 SJTD3_k127_4736334_0 1122138.AQUZ01000019_gene8174 1.107e-250 782.0 COG0737@1|root,COG1524@1|root,COG3379@1|root,COG0737@2|Bacteria,COG1524@2|Bacteria,COG3379@2|Bacteria,2HFJ5@201174|Actinobacteria,4DVDK@85009|Propionibacteriales 201174|Actinobacteria F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C SJTD3_k127_4744476_1 1242864.D187_003500 6.9e-16 88.0 COG0642@1|root,COG2205@2|Bacteria 1242864.D187_003500|- T PhoQ Sensor - - - - - - - - - - - - - SJTD3_k127_4744476_0 1128421.JAGA01000002_gene1333 7.774e-45 177.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SJTD3_k127_4758695_0 1499967.BAYZ01000026_gene1589 1.07e-18 94.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_4758695_2 926550.CLDAP_32820 4.19e-07 63.0 COG3307@1|root,COG3307@2|Bacteria,2G79D@200795|Chloroflexi 200795|Chloroflexi M O-Antigen ligase - - - - - - - - - - - - Wzy_C SJTD3_k127_4788507_3 665571.STHERM_c05740 1.171e-06 51.0 COG2146@1|root,COG2146@2|Bacteria 2|Bacteria P nitrite reductase [NAD(P)H] activity - - - ko:K05710 ko00360,ko01120,ko01220,map00360,map01120,map01220 M00545 R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske SJTD3_k127_4788507_0 1382356.JQMP01000001_gene1020 3.395e-125 421.0 COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2G66B@200795|Chloroflexi,27XNK@189775|Thermomicrobia 189775|Thermomicrobia M PFAM sugar transferase - - - - - - - - - - - - Bac_transf,CoA_binding_3 SJTD3_k127_4788507_1 479434.Sthe_1160 1.001e-110 387.0 COG2730@1|root,COG2730@2|Bacteria,2GBH8@200795|Chloroflexi,27Y4J@189775|Thermomicrobia 200795|Chloroflexi G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase SJTD3_k127_4788507_2 479434.Sthe_1975 2.61e-104 363.0 COG2730@1|root,COG2730@2|Bacteria,2GBH8@200795|Chloroflexi,27Y4J@189775|Thermomicrobia 189775|Thermomicrobia G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase SJTD3_k127_4841037_2 926560.KE387027_gene896 4.771e-07 55.0 COG4758@1|root,COG4758@2|Bacteria,1WKNW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S membrane - - - - - - - - - - - - DUF2154 SJTD3_k127_4841037_1 903814.ELI_0832 1.4e-07 60.0 COG2020@1|root,COG2020@2|Bacteria,1V495@1239|Firmicutes,24IHG@186801|Clostridia,25XZU@186806|Eubacteriaceae 186801|Clostridia O Phospholipid methyltransferase - - - - - - - - - - - - PEMT SJTD3_k127_4841037_0 1123023.JIAI01000001_gene7421 4.444e-73 254.0 COG0596@1|root,COG0596@2|Bacteria,2I97G@201174|Actinobacteria,4EE2D@85010|Pseudonocardiales 201174|Actinobacteria S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 SJTD3_k127_4848365_0 926550.CLDAP_10840 8.713e-67 235.0 COG1206@1|root,COG1206@2|Bacteria,2GBNY@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs - - 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA SJTD3_k127_4848365_1 926569.ANT_00760 3.347e-56 201.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4,Sigma70_r4_2 SJTD3_k127_4848365_2 357808.RoseRS_1536 3.685e-26 124.0 COG1196@1|root,COG1196@2|Bacteria,2G788@200795|Chloroflexi,376Y7@32061|Chloroflexia 32061|Chloroflexia D Domain of unknown function (DUF4349) - - - - - - - - - - - - DUF4349 SJTD3_k127_4863720_1 368407.Memar_2057 6.022e-65 238.0 COG0367@1|root,arCOG00071@2157|Archaea,2XV5E@28890|Euryarchaeota,2N9BC@224756|Methanomicrobia 224756|Methanomicrobia E TIGRFAM asparagine synthase (glutamine-hydrolyzing) asnB-1 - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SJTD3_k127_4863720_0 765420.OSCT_1472 9.038e-134 446.0 COG4166@1|root,COG4166@2|Bacteria,2G5TA@200795|Chloroflexi,376RY@32061|Chloroflexia 32061|Chloroflexia E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SJTD3_k127_4863720_2 479434.Sthe_0977 1.36e-20 102.0 COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi,27Y6X@189775|Thermomicrobia 189775|Thermomicrobia K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_4869325_0 1382356.JQMP01000003_gene2581 3.173e-240 756.0 COG0173@1|root,COG0173@2|Bacteria,2G5RX@200795|Chloroflexi,27XZT@189775|Thermomicrobia 189775|Thermomicrobia J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon SJTD3_k127_4869325_1 1287276.X752_17275 2.217e-06 58.0 COG1461@1|root,COG1461@2|Bacteria,1RIB0@1224|Proteobacteria,2U9X2@28211|Alphaproteobacteria,43P56@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Dihydroxyacetone kinase - - 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 SJTD3_k127_4871557_1 326427.Cagg_3774 9.029e-62 218.0 COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2G65W@200795|Chloroflexi,374YB@32061|Chloroflexia 32061|Chloroflexia M PFAM transferase hexapeptide repeat containing protein - - 2.7.7.13,5.4.2.8 ko:K16881 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114,M00362 R00885,R01818 RC00002,RC00408 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III SJTD3_k127_4871557_0 446470.Snas_0537 1.793e-125 445.0 COG3055@1|root,COG3055@2|Bacteria 2|Bacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - Big_2,Kelch_1,Kelch_3,Kelch_6 SJTD3_k127_4871557_2 926560.KE387023_gene3015 3.079e-19 104.0 COG3055@1|root,COG3055@2|Bacteria,1WK3E@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM Kelch motif - - - - - - - - - - - - Kelch_1 SJTD3_k127_4871557_3 1132442.KB889752_gene3016 1.642e-10 76.0 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZBKV@1386|Bacillus 91061|Bacilli L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Excalibur,HHH_3,LTD,Lactamase_B,SLH SJTD3_k127_4875226_0 1127134.NOCYR_3541 3.833e-109 374.0 COG3540@1|root,COG3540@2|Bacteria,2GJCI@201174|Actinobacteria,4FWDN@85025|Nocardiaceae 201174|Actinobacteria P alkaline phosphatase phoD - 3.1.3.1 ko:K01077,ko:K01113 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 M00126 R02135,R04620 RC00017 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 - - - PhoD,PhoD_N SJTD3_k127_4875226_1 760192.Halhy_1193 6.486e-21 95.0 COG2010@1|root,COG2010@2|Bacteria,4NHQV@976|Bacteroidetes,1IXTS@117747|Sphingobacteriia 976|Bacteroidetes C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C,Cytochrome_CBB3 SJTD3_k127_4876802_1 338963.Pcar_1222 2.264e-09 66.0 COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,42MGP@68525|delta/epsilon subdivisions,2WIZ2@28221|Deltaproteobacteria,43RZ4@69541|Desulfuromonadales 28221|Deltaproteobacteria L Bacterial DNA polymerase III alpha subunit dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon SJTD3_k127_4876802_0 1382356.JQMP01000003_gene2177 1.225e-59 210.0 COG0764@1|root,COG0764@2|Bacteria,2G8P4@200795|Chloroflexi,27YA6@189775|Thermomicrobia 189775|Thermomicrobia I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA SJTD3_k127_4885572_0 1382356.JQMP01000001_gene982 4.64e-51 194.0 COG1940@1|root,COG1940@2|Bacteria,2G6IH@200795|Chloroflexi,27XP3@189775|Thermomicrobia 189775|Thermomicrobia GK ROK family - - 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - ROK SJTD3_k127_4885572_1 243233.MCA0497 2.146e-29 121.0 COG2154@1|root,COG2154@2|Bacteria,1RH99@1224|Proteobacteria,1S5YX@1236|Gammaproteobacteria,1XGKV@135618|Methylococcales 135618|Methylococcales H Pterin 4 alpha carbinolamine dehydratase - - 4.2.1.96 ko:K01724 ko00790,map00790 - R04734 RC01208 ko00000,ko00001,ko01000,ko04147 - - - Pterin_4a SJTD3_k127_4887309_0 292459.STH724 5.146e-108 358.0 COG2719@1|root,COG2719@2|Bacteria,1TRHQ@1239|Firmicutes,248CW@186801|Clostridia 186801|Clostridia S PFAM SpoVR spoVR - - ko:K06415 - - - - ko00000 - - - SpoVR SJTD3_k127_4887309_1 266117.Rxyl_0172 1.136e-57 207.0 COG0500@1|root,COG2226@2|Bacteria,2HEP0@201174|Actinobacteria,4CTFJ@84995|Rubrobacteria 84995|Rubrobacteria Q ubiE/COQ5 methyltransferase family - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_4894393_1 368407.Memar_0776 9.475e-12 78.0 arCOG03383@1|root,arCOG03383@2157|Archaea,2Y7A4@28890|Euryarchaeota,2NB4Y@224756|Methanomicrobia 224756|Methanomicrobia U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 SJTD3_k127_4894393_0 309801.trd_1658 8.341e-26 123.0 COG2340@1|root,COG2340@2|Bacteria,2G8G6@200795|Chloroflexi,27XTT@189775|Thermomicrobia 189775|Thermomicrobia S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP SJTD3_k127_4902778_1 1382356.JQMP01000003_gene1473 7.653e-07 56.0 COG0018@1|root,COG0018@2|Bacteria,2G6DK@200795|Chloroflexi,27XN1@189775|Thermomicrobia 189775|Thermomicrobia J DALR anticodon binding domain argS - 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - DALR_1,tRNA-synt_1d SJTD3_k127_4902778_0 479434.Sthe_3482 8.634e-165 526.0 COG2041@1|root,COG2041@2|Bacteria,2GB1N@200795|Chloroflexi,27Z7Z@189775|Thermomicrobia 189775|Thermomicrobia S Mo-co oxidoreductase dimerisation domain - - - - - - - - - - - - Mo-co_dimer,Oxidored_molyb SJTD3_k127_4905987_4 525904.Tter_2239 2.925e-50 188.0 COG1403@1|root,COG1403@2|Bacteria 2|Bacteria V endonuclease activity - - - ko:K07451 - - - - ko00000,ko01000,ko02048 - - - HNH SJTD3_k127_4905987_1 35754.JNYJ01000019_gene80 1.295e-137 472.0 COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales 201174|Actinobacteria KT Transcriptional regulator - - - - - - - - - - - - AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12 SJTD3_k127_4905987_0 1444711.CCJF01000005_gene546 1.337e-144 498.0 COG1404@1|root,COG3391@1|root,COG1404@2|Bacteria,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_5,Calx-beta,SBBP SJTD3_k127_4905987_7 1121904.ARBP01000036_gene2088 0.0002231 55.0 COG4099@1|root,COG4733@1|root,COG4099@2|Bacteria,COG4733@2|Bacteria,4NK2V@976|Bacteroidetes 976|Bacteroidetes O Fibronectin type III domain protein - - - - - - - - - - - - Laminin_G_3,PA14,fn3 SJTD3_k127_4905987_5 511051.CSE_11710 4.122e-13 84.0 COG0747@1|root,COG0747@2|Bacteria 2|Bacteria E dipeptide transport appA - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SJTD3_k127_4905987_2 357808.RoseRS_0613 2.304e-115 389.0 COG5002@1|root,COG5002@2|Bacteria,2G6F5@200795|Chloroflexi,3781R@32061|Chloroflexia 32061|Chloroflexia T PFAM ATP-binding region, ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA SJTD3_k127_4905987_3 357808.RoseRS_0612 3.87e-65 226.0 COG0745@1|root,COG0745@2|Bacteria,2G6H6@200795|Chloroflexi,3752R@32061|Chloroflexia 32061|Chloroflexia K Two component transcriptional regulator, winged helix family - - - - - - - - - - - - Response_reg,Trans_reg_C SJTD3_k127_4907372_1 357808.RoseRS_0521 1.26e-72 259.0 28II6@1|root,2Z8JB@2|Bacteria,2G7FN@200795|Chloroflexi,375CV@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_4907372_0 765420.OSCT_2793 2.535e-108 376.0 COG1070@1|root,COG1070@2|Bacteria,2G6JV@200795|Chloroflexi,375CS@32061|Chloroflexia 32061|Chloroflexia G MutL protein - - - - - - - - - - - - MutL SJTD3_k127_4907372_2 765420.OSCT_2792 6.603e-29 124.0 2ANS9@1|root,31DS7@2|Bacteria,2G7CA@200795|Chloroflexi,375US@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_4907372_5 383372.Rcas_2219 1.476e-22 113.0 COG4886@1|root,COG4886@2|Bacteria,2G906@200795|Chloroflexi,375M2@32061|Chloroflexia 32061|Chloroflexia S Leucine-rich repeat (LRR) protein - - - - - - - - - - - - - SJTD3_k127_4907372_3 1128421.JAGA01000002_gene448 1.114e-27 121.0 29ZH8@1|root,30MGZ@2|Bacteria,2NQ83@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_4907372_4 1521187.JPIM01000068_gene760 1.114e-25 117.0 28MEN@1|root,2ZASA@2|Bacteria,2G97S@200795|Chloroflexi,375P3@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_4907372_6 1170562.Cal6303_3896 5.135e-20 102.0 COG1295@1|root,COG1295@2|Bacteria,1G1HS@1117|Cyanobacteria,1HM81@1161|Nostocales 1117|Cyanobacteria S TIGRFAM YihY family protein (not ribonuclease BN) rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB SJTD3_k127_4907372_7 1313172.YM304_39170 2.357e-18 91.0 COG0789@1|root,COG0789@2|Bacteria,2GR1T@201174|Actinobacteria,4CN4Z@84992|Acidimicrobiia 84992|Acidimicrobiia K helix_turn_helix, mercury resistance - - - ko:K13640 - - - - ko00000,ko03000 - - - MerR_1 SJTD3_k127_4907372_8 1095772.CAHH01000049_gene42 2.473e-10 70.0 COG0739@1|root,COG0739@2|Bacteria,2I2K6@201174|Actinobacteria 201174|Actinobacteria M Peptidase, M23 - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 SJTD3_k127_4909048_0 525904.Tter_0025 4.641e-90 313.0 COG1195@1|root,COG1195@2|Bacteria,2NPEJ@2323|unclassified Bacteria 2|Bacteria L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - ko:K03629,ko:K07459 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N SJTD3_k127_4912086_1 986075.CathTA2_0257 7.591e-43 163.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA - - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N SJTD3_k127_4912086_0 479434.Sthe_1110 2.273e-174 562.0 COG1190@1|root,COG1190@2|Bacteria,2G65Z@200795|Chloroflexi,27XMG@189775|Thermomicrobia 189775|Thermomicrobia J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon SJTD3_k127_4912086_2 1144275.COCOR_07574 2.375e-14 81.0 2AI3B@1|root,318H4@2|Bacteria,1PA8C@1224|Proteobacteria 1224|Proteobacteria S Immunity protein Imm5 - - - - - - - - - - - - Imm5 SJTD3_k127_4912109_3 926550.CLDAP_30360 4.839e-57 227.0 COG3391@1|root,COG5305@1|root,COG3391@2|Bacteria,COG5305@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - PMT_2 SJTD3_k127_4912109_2 1480694.DC28_12355 6.475e-122 398.0 COG0395@1|root,COG0395@2|Bacteria,2J5Z6@203691|Spirochaetes 203691|Spirochaetes P PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K10119,ko:K10234 ko02010,map02010 M00196,M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28,3.A.1.1.32,3.A.1.1.8 - - BPD_transp_1 SJTD3_k127_4912109_1 1480694.DC28_12360 7.93e-148 476.0 COG1175@1|root,COG1175@2|Bacteria,2J5SW@203691|Spirochaetes 203691|Spirochaetes P PFAM Binding-protein-dependent transport system inner membrane component - - - ko:K02025,ko:K10233 ko02010,map02010 M00201,M00207 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.32,3.A.1.1.8 - - BPD_transp_1 SJTD3_k127_4912109_0 1280390.CBQR020000054_gene1064 3.046e-154 500.0 COG1653@1|root,COG1653@2|Bacteria,1UY8X@1239|Firmicutes,4HT5T@91061|Bacilli,26RVV@186822|Paenibacillaceae 91061|Bacilli G ABC transporter substrate-binding protein - - - ko:K10232 ko02010,map02010 M00201 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.32,3.A.1.1.8 - - SBP_bac_1 SJTD3_k127_4912109_4 861299.J421_0673 4.227e-44 168.0 2DWKV@1|root,340YA@2|Bacteria,1ZTYS@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - SJTD3_k127_4921191_1 765420.OSCT_2676 3.04e-38 164.0 COG0631@1|root,COG0631@2|Bacteria,2G8I1@200795|Chloroflexi,375BS@32061|Chloroflexia 32061|Chloroflexia T protein phosphatase 2C domain protein - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 SJTD3_k127_4921191_0 1128421.JAGA01000002_gene1679 2.098e-201 655.0 COG0317@1|root,COG0317@2|Bacteria,2NNM0@2323|unclassified Bacteria 2|Bacteria KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 ko:K00951,ko:K01139 ko00230,map00230 - R00336,R00429 RC00002,RC00078 ko00000,ko00001,ko01000,ko03009 - - iSFV_1184.SFV_2673 ACT_4,HD_4,RelA_SpoT,TGS SJTD3_k127_4921620_0 1128421.JAGA01000003_gene3149 5.847e-108 358.0 COG0449@1|root,COG0449@2|Bacteria,2NNWC@2323|unclassified Bacteria 2|Bacteria M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iAF987.Gmet_1487 GATase_6,SIS SJTD3_k127_4921620_2 1449126.JQKL01000011_gene3595 1.544e-33 147.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,24GKC@186801|Clostridia 186801|Clostridia S YbbR-like protein - - - - - - - - - - - - YbbR SJTD3_k127_4921620_1 767817.Desgi_4309 2.968e-58 212.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,260Y7@186807|Peptococcaceae 186801|Clostridia S TIGRFAM Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily - - - - - - - - - - - - Hydrolase_3 SJTD3_k127_4922604_0 479434.Sthe_0383 3.138e-279 874.0 COG0550@1|root,COG0550@2|Bacteria,2G5ZR@200795|Chloroflexi,27XYG@189775|Thermomicrobia 189775|Thermomicrobia L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom SJTD3_k127_4923860_1 267608.RSp0711 1.513e-31 136.0 COG5486@1|root,COG5486@2|Bacteria,1R6FN@1224|Proteobacteria,2VMCU@28216|Betaproteobacteria,1K22S@119060|Burkholderiaceae 28216|Betaproteobacteria S Predicted metal-binding integral membrane protein (DUF2182) - - - - - - - - - - - - DUF2182 SJTD3_k127_4923860_0 1173026.Glo7428_4019 3.144e-240 748.0 COG3391@1|root,COG3391@2|Bacteria,1G136@1117|Cyanobacteria 1117|Cyanobacteria S PFAM 56kDa selenium binding protein (SBP56) - - - ko:K17285 - - - - ko00000,ko04147 - - - SBP56 SJTD3_k127_4923860_2 994479.GL877878_gene3151 2.265e-11 64.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DZ55@85010|Pseudonocardiales 201174|Actinobacteria K transcriptional regulator, LuxR family - - 2.7.11.1 ko:K08282 - - - - ko00000,ko01000 - - - AAA_22,GerE,NB-ARC,TPR_12 SJTD3_k127_4925706_2 379066.GAU_3906 4.125e-71 262.0 COG3055@1|root,COG3055@2|Bacteria,1ZUV8@142182|Gemmatimonadetes 142182|Gemmatimonadetes S Galactose oxidase, central domain - - - - - - - - - - - - Kelch_4 SJTD3_k127_4925706_7 479434.Sthe_0357 7.464e-34 149.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_4925706_4 1278073.MYSTI_06762 2.767e-51 188.0 COG0454@1|root,COG0454@2|Bacteria,1RIFC@1224|Proteobacteria,42XMV@68525|delta/epsilon subdivisions,2WX09@28221|Deltaproteobacteria,2Z14Y@29|Myxococcales 28221|Deltaproteobacteria K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_7 SJTD3_k127_4925706_3 402777.KB235898_gene5104 1.994e-62 225.0 COG5113@1|root,COG3236@2|Bacteria,1G60B@1117|Cyanobacteria,1HB4V@1150|Oscillatoriales 1117|Cyanobacteria O TIGRFAM conserved - - - ko:K09935 - - - - ko00000 - - - DUF1768 SJTD3_k127_4925706_5 749927.AMED_2397 3.69e-49 184.0 COG1633@1|root,COG1633@2|Bacteria,2IDZ9@201174|Actinobacteria,4E2JH@85010|Pseudonocardiales 201174|Actinobacteria S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - - - - - - - - - - - SJTD3_k127_4925706_1 765420.OSCT_0642 3.4e-115 376.0 COG2197@1|root,COG2197@2|Bacteria,2G7U4@200795|Chloroflexi,376QK@32061|Chloroflexia 32061|Chloroflexia T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg SJTD3_k127_4925706_0 765420.OSCT_0643 1.013e-169 559.0 COG4585@1|root,COG4585@2|Bacteria,2G7W5@200795|Chloroflexi,3767N@32061|Chloroflexia 32061|Chloroflexia T Histidine kinase-like ATPases - - - - - - - - - - - - - SJTD3_k127_4925706_6 1394178.AWOO02000007_gene3133 1.128e-39 153.0 2DP6X@1|root,330TB@2|Bacteria,2IQIH@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_4927528_0 1340493.JNIF01000003_gene4247 4.844e-164 527.0 COG0677@1|root,COG0677@2|Bacteria,3Y30B@57723|Acidobacteria 57723|Acidobacteria M Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SJTD3_k127_4927528_2 357808.RoseRS_2408 1.377e-85 299.0 COG0598@1|root,COG0598@2|Bacteria,2G6EQ@200795|Chloroflexi,375MB@32061|Chloroflexia 32061|Chloroflexia P Mediates influx of magnesium ions corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA SJTD3_k127_4927528_5 383372.Rcas_1915 1.346e-47 177.0 COG1595@1|root,COG1595@2|Bacteria,2GB53@200795|Chloroflexi,377AG@32061|Chloroflexia 32061|Chloroflexia K RNA polymerase, sigma-24 subunit, ECF subfamily - - - - - - - - - - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_4927528_3 1173024.KI912148_gene3260 1.154e-59 218.0 COG1173@1|root,COG1173@2|Bacteria,1G0CD@1117|Cyanobacteria,1JK5J@1189|Stigonemataceae 1117|Cyanobacteria EP N-terminal TM domain of oligopeptide transport permease C appC - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N SJTD3_k127_4927528_4 1033734.CAET01000026_gene1049 1.841e-50 195.0 COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,4HATR@91061|Bacilli,1ZCAV@1386|Bacillus 91061|Bacilli P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components appB GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 SJTD3_k127_4927528_1 479434.Sthe_1775 4.849e-91 310.0 COG1136@1|root,COG1136@2|Bacteria,2G6B5@200795|Chloroflexi,27YCE@189775|Thermomicrobia 189775|Thermomicrobia V ATPases associated with a variety of cellular activities - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_4927528_6 479434.Sthe_1776 8.718e-21 102.0 COG0577@1|root,COG3127@1|root,COG0577@2|Bacteria,COG3127@2|Bacteria,2G6CK@200795|Chloroflexi,27Z42@189775|Thermomicrobia 189775|Thermomicrobia V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX SJTD3_k127_4939003_2 1128421.JAGA01000002_gene5 5.039e-112 372.0 COG0484@1|root,COG0484@2|Bacteria,2NQI8@2323|unclassified Bacteria 2|Bacteria O DnaJ molecular chaperone homology domain cbpA - - ko:K03686,ko:K05516 - - - - ko00000,ko03029,ko03036,ko03110 - - - DnaJ,DnaJ_C SJTD3_k127_4939003_6 1128421.JAGA01000002_gene6 2.957e-28 118.0 COG0789@1|root,COG0789@2|Bacteria,2NPTR@2323|unclassified Bacteria 2|Bacteria K Transcriptional regulator, MerR family hspR GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K13640 - - - - ko00000,ko03000 - - - MerR_1 SJTD3_k127_4939003_1 1521187.JPIM01000135_gene1823 3.278e-305 955.0 COG0542@1|root,COG0542@2|Bacteria,2G62D@200795|Chloroflexi,3753A@32061|Chloroflexia 32061|Chloroflexia O ATPase associated with various cellular activities, AAA_5 - - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N SJTD3_k127_4939003_4 479434.Sthe_1547 6.803e-47 172.0 2CMJR@1|root,32U2B@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_4939003_5 1114856.C496_06587 1.312e-39 153.0 2CG7F@1|root,2N5FI@2157|Archaea,2XZIM@28890|Euryarchaeota,23X4N@183963|Halobacteria 183963|Halobacteria - - - - - - - - - - - - - - - SJTD3_k127_4939003_3 221288.JH992901_gene1754 2.957e-67 234.0 COG1695@1|root,COG1695@2|Bacteria,1G56C@1117|Cyanobacteria,1JK4U@1189|Stigonemataceae 1117|Cyanobacteria K Virulence activator alpha C-term - - - - - - - - - - - - PadR,Vir_act_alpha_C SJTD3_k127_4939003_0 1128421.JAGA01000003_gene2753 0.0 1405.0 COG0474@1|root,COG0474@2|Bacteria,2NNSC@2323|unclassified Bacteria 2|Bacteria P Cation transporter/ATPase, N-terminus pacL2 - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 SJTD3_k127_4939003_7 118168.MC7420_7764 1.919e-25 111.0 2F3J5@1|root,33WCQ@2|Bacteria,1GDPZ@1117|Cyanobacteria,1HFQC@1150|Oscillatoriales 1117|Cyanobacteria - - - - - - - - - - - - - - - SJTD3_k127_4939003_9 717605.Theco_3052 1.387e-05 56.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli,26R4Y@186822|Paenibacillaceae 91061|Bacilli C Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 SJTD3_k127_4939003_8 1040987.AZUY01000036_gene2249 2.189e-10 62.0 COG0491@1|root,COG0491@2|Bacteria,1MY6G@1224|Proteobacteria,2TTBX@28211|Alphaproteobacteria,43JIG@69277|Phyllobacteriaceae 28211|Alphaproteobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SJTD3_k127_4939904_1 1172180.KB911802_gene5228 2.707e-29 119.0 COG0662@1|root,COG0662@2|Bacteria,2IEY0@201174|Actinobacteria 201174|Actinobacteria G Cupin domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_4939904_0 1121377.KB906424_gene3959 1.687e-128 443.0 COG2771@1|root,COG3903@1|root,COG2771@2|Bacteria,COG3903@2|Bacteria 2|Bacteria K ADP binding - - - ko:K21405 - - - - ko00000,ko03000 - - - AAA_16,AAA_22,BTAD,DUF4019,GerE,NB-ARC,TPR_12 SJTD3_k127_4955555_0 765420.OSCT_2500 2.109e-60 215.0 COG1595@1|root,COG1595@2|Bacteria,2G6MG@200795|Chloroflexi,375K5@32061|Chloroflexia 32061|Chloroflexia K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_4955555_2 926569.ANT_29490 1.012e-08 66.0 COG5662@1|root,COG5662@2|Bacteria,2G9S9@200795|Chloroflexi 200795|Chloroflexi K AntiSigma factor - - - - - - - - - - - - zf-HC2 SJTD3_k127_4963983_0 767817.Desgi_4194 4.45e-52 205.0 COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia,2676Q@186807|Peptococcaceae 186801|Clostridia M Bacterial capsule synthesis protein PGA_cap capA - - ko:K07282 - - - - ko00000 - - - PGA_cap,Peptidase_M15 SJTD3_k127_4965893_0 1521187.JPIM01000008_gene2087 3.066e-120 399.0 COG1506@1|root,COG1506@2|Bacteria,2G907@200795|Chloroflexi 200795|Chloroflexi E Alpha/beta hydrolase of unknown function (DUF1100) - - - - - - - - - - - - Peptidase_S9 SJTD3_k127_4965893_2 396588.Tgr7_1139 6.779e-29 122.0 COG0680@1|root,COG0680@2|Bacteria,1NGWH@1224|Proteobacteria 1224|Proteobacteria C TIGRFAM hydrogenase maturation protease vhtD - - ko:K03605 - - - - ko00000,ko01000,ko01002 - - - HycI SJTD3_k127_4965893_3 247490.KSU1_A0079 1.086e-06 54.0 2DCC8@1|root,2ZDND@2|Bacteria 2|Bacteria S Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - - - - - - - - - - HypA SJTD3_k127_4965893_1 1173029.JH980292_gene174 8.82e-76 261.0 COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,1H71F@1150|Oscillatoriales 1117|Cyanobacteria O Belongs to the carbamoyltransferase HypF family hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF SJTD3_k127_4967498_2 469616.FMAG_00797 1.148e-13 78.0 COG0619@1|root,COG0619@2|Bacteria,378HU@32066|Fusobacteria 32066|Fusobacteria P Cobalt transport protein - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ SJTD3_k127_4967498_0 1382306.JNIM01000001_gene3964 2.149e-153 505.0 COG1123@1|root,COG4172@2|Bacteria,2GBJ7@200795|Chloroflexi 200795|Chloroflexi P COGs COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase - - - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran SJTD3_k127_4967498_1 720555.BATR1942_04335 3.567e-32 132.0 COG4721@1|root,COG4721@2|Bacteria,1V39N@1239|Firmicutes,4HF32@91061|Bacilli,1ZEPF@1386|Bacillus 91061|Bacilli S ABC-type cobalt transport system, permease component ykoE - - ko:K16925 - M00582 - - ko00000,ko00002,ko02000 3.A.1.30 - - ABC_cobalt SJTD3_k127_4971308_3 1047013.AQSP01000144_gene828 4.594e-07 62.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K20444 - - - - ko00000,ko01000,ko01005,ko02000 4.D.1.3 GT2,GT4 - Glyco_trans_1_4,Glyco_transf_11,Methyltransf_21 SJTD3_k127_4971308_0 926550.CLDAP_22690 5.167e-69 246.0 COG1215@1|root,COG2148@1|root,COG1215@2|Bacteria,COG2148@2|Bacteria,2G866@200795|Chloroflexi 200795|Chloroflexi M Bacterial sugar transferase - - - - - - - - - - - - Bac_transf,Glycos_transf_2 SJTD3_k127_4971308_1 1449976.KALB_8422 1.083e-20 106.0 COG2244@1|root,COG2244@2|Bacteria,2H55P@201174|Actinobacteria,4DY6N@85010|Pseudonocardiales 201174|Actinobacteria S Polysaccharide biosynthesis protein - - - ko:K03328,ko:K16695 - - - - ko00000,ko02000 2.A.66.2,2.A.66.2.7 - - Polysacc_synt_3,Polysacc_synt_C SJTD3_k127_4974937_3 525904.Tter_0616 2.366e-06 53.0 arCOG09854@1|root,3325R@2|Bacteria,2NRU9@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_4974937_0 485913.Krac_5284 4.987e-51 186.0 COG2318@1|root,COG2318@2|Bacteria,2G77R@200795|Chloroflexi 200795|Chloroflexi S DinB superfamily - - - - - - - - - - - - DinB_2 SJTD3_k127_4974937_2 1341151.ASZU01000014_gene2204 2.036e-08 64.0 298S5@1|root,2ZVWF@2|Bacteria,1V8I3@1239|Firmicutes,4HHTT@91061|Bacilli,27CFI@186824|Thermoactinomycetaceae 91061|Bacilli S Protein of unknown function with PCYCGC motif - - - - - - - - - - - - PCYCGC SJTD3_k127_4974937_1 1128421.JAGA01000003_gene3354 4.189e-16 86.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups remC - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_2,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_4982957_0 1192034.CAP_7461 7.392e-278 880.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1MU0R@1224|Proteobacteria,42NYJ@68525|delta/epsilon subdivisions,2WKWS@28221|Deltaproteobacteria 28221|Deltaproteobacteria GT Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - 2.7.9.2 ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 M00173,M00374 R00199 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000 - - - PEP-utilizers,PPDK_N SJTD3_k127_4982957_2 552811.Dehly_1398 4.773e-44 168.0 COG1309@1|root,COG1309@2|Bacteria,2G72N@200795|Chloroflexi,34DFE@301297|Dehalococcoidia 301297|Dehalococcoidia K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N SJTD3_k127_4982957_1 926550.CLDAP_25500 6.333e-102 344.0 COG5557@1|root,COG5557@2|Bacteria,2G703@200795|Chloroflexi 200795|Chloroflexi C Polysulphide reductase, NrfD - - - ko:K00185 - - - - ko00000 5.A.3 - - NrfD SJTD3_k127_4985368_2 1210884.HG799463_gene9578 1.197e-66 241.0 COG0072@1|root,COG0072@2|Bacteria,2IX0Q@203682|Planctomycetes 203682|Planctomycetes J Phenylalanyl-tRNA synthetase, beta subunit pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind SJTD3_k127_4985368_3 1454007.JAUG01000041_gene558 1.845e-19 94.0 2EA47@1|root,33494@2|Bacteria,4P7ZV@976|Bacteroidetes,1J00A@117747|Sphingobacteriia 976|Bacteroidetes - - - - - - - - - - - - - - - SJTD3_k127_4985368_1 1128421.JAGA01000002_gene887 6.608e-110 362.0 COG0647@1|root,COG0647@2|Bacteria,2NPEG@2323|unclassified Bacteria 2|Bacteria G Haloacid dehalogenase-like hydrolase nagD GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 - ko:K02566 - - - - ko00000 - - - Hydrolase_6,Hydrolase_like SJTD3_k127_4985368_0 1121019.AUMN01000017_gene2277 2.733e-125 413.0 COG1228@1|root,COG1228@2|Bacteria,2I9IW@201174|Actinobacteria,1W8Q4@1268|Micrococcaceae 201174|Actinobacteria Q Amidohydrolase family - - - - - - - - - - - - Amidohydro_1,Amidohydro_3 SJTD3_k127_4988130_2 1243664.CAVL020000028_gene115 0.0002513 55.0 COG3103@1|root,COG5492@1|root,COG3103@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - 3D,Big_2,Big_3_2,CBM_X2,SH3_3,SLH SJTD3_k127_4988130_0 671143.DAMO_0021 2.235e-33 150.0 COG3055@1|root,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria 2|Bacteria G Galactose oxidase, central domain - - - - - - - - - - - - Kelch_1,Kelch_4,Kelch_6 SJTD3_k127_4988130_1 35754.JNYJ01000064_gene1394 3.452e-22 113.0 COG1404@1|root,COG2133@1|root,COG3291@1|root,COG4782@1|root,COG1404@2|Bacteria,COG2133@2|Bacteria,COG3291@2|Bacteria,COG4782@2|Bacteria,2GJFY@201174|Actinobacteria,4DASA@85008|Micromonosporales 201174|Actinobacteria G Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - - - - - - - - - - Big_5,CarboxypepD_reg,F5_F8_type_C,GSDH,PA14,PKD SJTD3_k127_4994174_5 309801.trd_1854 1.197e-11 68.0 COG0762@1|root,COG0762@2|Bacteria,2G9QH@200795|Chloroflexi,27YQI@189775|Thermomicrobia 189775|Thermomicrobia S YGGT family - - - ko:K02221 - - - - ko00000,ko02044 - - - YGGT SJTD3_k127_4994174_3 479434.Sthe_2072 5.346e-36 145.0 COG1825@1|root,COG1825@2|Bacteria,2G7A4@200795|Chloroflexi,27YEB@189775|Thermomicrobia 189775|Thermomicrobia J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance ctc - - ko:K02897 ko03010,map03010 M00178 - - ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L25p,Ribosomal_TL5_C SJTD3_k127_4994174_2 926569.ANT_20720 3.297e-138 451.0 COG3842@1|root,COG3842@2|Bacteria,2G5X9@200795|Chloroflexi 200795|Chloroflexi P PFAM ABC transporter related - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 SJTD3_k127_4994174_1 765420.OSCT_1154 1.219e-145 467.0 COG1077@1|root,COG1077@2|Bacteria,2G5KV@200795|Chloroflexi,374UP@32061|Chloroflexia 32061|Chloroflexia D TIGRFAM cell shape determining protein, MreB Mrl family - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SJTD3_k127_4994174_4 316274.Haur_4073 2.822e-33 135.0 COG0355@1|root,COG0355@2|Bacteria,2G70H@200795|Chloroflexi,375QG@32061|Chloroflexia 32061|Chloroflexia C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N SJTD3_k127_4994174_0 525904.Tter_0063 1.051e-229 718.0 COG0055@1|root,COG0055@2|Bacteria,2NNRB@2323|unclassified Bacteria 2|Bacteria C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - - ATP-synt_ab,ATP-synt_ab_N SJTD3_k127_4995779_0 926550.CLDAP_15930 6.045e-94 315.0 COG1304@1|root,COG1304@2|Bacteria,2G5RF@200795|Chloroflexi 200795|Chloroflexi H Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni - 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh SJTD3_k127_4995779_2 479434.Sthe_2915 4.773e-53 194.0 COG0494@1|root,COG0494@2|Bacteria 2|Bacteria L nUDIX hydrolase - - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - - NUDIX SJTD3_k127_4995779_1 1262915.BN574_00167 4.556e-58 218.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4H2EW@909932|Negativicutes 909932|Negativicutes J Specifically methylates the N7 position of a guanine in 16S rRNA rsmG - 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB SJTD3_k127_5001018_2 926550.CLDAP_22900 1.503e-95 317.0 COG1063@1|root,COG1063@2|Bacteria,2G6PM@200795|Chloroflexi 200795|Chloroflexi E Alcohol dehydrogenase GroES-like domain - - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N SJTD3_k127_5001018_6 1226322.HMPREF1545_03070 2.088e-58 212.0 COG1878@1|root,COG1878@2|Bacteria 2|Bacteria S arylformamidase activity - - - - - - - - - - - - Cyclase SJTD3_k127_5001018_5 1392838.AWNM01000020_gene3821 3.555e-60 216.0 COG1028@1|root,COG1028@2|Bacteria,1RG5D@1224|Proteobacteria,2W2YR@28216|Betaproteobacteria,3T48M@506|Alcaligenaceae 28216|Betaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SJTD3_k127_5001018_8 266779.Meso_0263 1.239e-47 184.0 COG1172@1|root,COG1172@2|Bacteria,1PRXF@1224|Proteobacteria,2TV02@28211|Alphaproteobacteria,43IT8@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_5001018_3 1499967.BAYZ01000028_gene1250 8.535e-88 304.0 COG1879@1|root,COG1879@2|Bacteria 2|Bacteria G ABC-type sugar transport system periplasmic component - - - ko:K10439,ko:K10543 ko02010,ko02030,map02010,map02030 M00212,M00215 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.4 - - Peripla_BP_4 SJTD3_k127_5001018_0 1007103.AFHW01000025_gene316 6.345e-142 467.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,4H9VK@91061|Bacilli,26SVT@186822|Paenibacillaceae 91061|Bacilli G import. Responsible for energy coupling to the transport system rbsA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_5001018_4 266835.14021871 1.539e-63 231.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,2U0D6@28211|Alphaproteobacteria,43QWC@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Branched-chain amino acid transport system / permease component - - - ko:K02057,ko:K10440,ko:K17209 ko02010,map02010 M00212,M00221,M00592 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.21 - - BPD_transp_2 SJTD3_k127_5001018_7 1121472.AQWN01000011_gene1210 2.849e-48 184.0 COG1082@1|root,COG1082@2|Bacteria,1TRXP@1239|Firmicutes,24EWV@186801|Clostridia,262DG@186807|Peptococcaceae 186801|Clostridia G Xylose isomerase-like TIM barrel - - - ko:K22233 ko00562,map00562 - R11772 - ko00000,ko00001,ko01000 - - - AP_endonuc_2 SJTD3_k127_5001018_1 525904.Tter_1528 9.817e-110 365.0 COG3959@1|root,COG3959@2|Bacteria,2NP12@2323|unclassified Bacteria 2|Bacteria G Transketolase, thiamine diphosphate binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transketolase_N SJTD3_k127_5001018_9 869210.Marky_0944 1.321e-26 111.0 COG3958@1|root,COG3958@2|Bacteria,1WKB8@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus G Transketolase, pyrimidine binding domain - - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C SJTD3_k127_5003003_2 1449080.JQMV01000003_gene2105 9.596e-43 160.0 COG1804@1|root,COG1804@2|Bacteria,1WIR7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus C L-carnitine dehydratase bile acid-inducible protein F - - - - - - - - - - - - CoA_transf_3 SJTD3_k127_5003003_1 926550.CLDAP_16410 9.63e-78 272.0 COG3872@1|root,COG3872@2|Bacteria,2G5XQ@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF1385) - - - ko:K09153 - - - - ko00000 - - - DUF1385 SJTD3_k127_5003003_0 1123368.AUIS01000001_gene1960 2.909e-120 394.0 COG4221@1|root,COG4221@2|Bacteria,1MUU6@1224|Proteobacteria,1RZGC@1236|Gammaproteobacteria 1236|Gammaproteobacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short SJTD3_k127_501381_1 935567.JAES01000032_gene1624 1.202e-08 59.0 2FHU1@1|root,349MA@2|Bacteria 2|Bacteria S CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi SJTD3_k127_501381_0 1173024.KI912153_gene217 1.186e-142 459.0 COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae 1117|Cyanobacteria F Dihydroorotate dehydrogenase - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh SJTD3_k127_501381_2 1347368.HG964404_gene5065 5.725e-05 48.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,1ZS4T@1386|Bacillus 91061|Bacilli F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases cpdB - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CHB_HEX_C_1,Gram_pos_anchor,Metallophos,SLH SJTD3_k127_5021266_1 383372.Rcas_2782 2.488e-77 267.0 COG0745@1|root,COG0745@2|Bacteria,2GBG4@200795|Chloroflexi,376MR@32061|Chloroflexia 32061|Chloroflexia K PFAM response regulator receiver - - - - - - - - - - - - Response_reg,Trans_reg_C SJTD3_k127_5021266_2 42256.RradSPS_1352 3.221e-67 243.0 COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HAMP,HATPase_c,HisKA SJTD3_k127_5021266_4 357808.RoseRS_0256 1.545e-10 68.0 COG1734@1|root,COG1734@2|Bacteria,2G7BM@200795|Chloroflexi,377WS@32061|Chloroflexia 32061|Chloroflexia K PFAM zinc finger, DksA TraR C4-type - - - ko:K06204 ko02026,map02026 - - - ko00000,ko00001,ko03000,ko03009,ko03021 - - - zf-dskA_traR SJTD3_k127_5021266_0 479434.Sthe_1942 2.685e-142 467.0 COG0334@1|root,COG0334@2|Bacteria,2G5SR@200795|Chloroflexi,27XVS@189775|Thermomicrobia 200795|Chloroflexi C Belongs to the Glu Leu Phe Val dehydrogenases family - - 1.4.1.3 ko:K00261 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 M00740 R00243,R00248 RC00006,RC02799 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ELFV_dehydrog,ELFV_dehydrog_N SJTD3_k127_5021266_3 1382306.JNIM01000001_gene3833 1.253e-16 81.0 COG0663@1|root,COG0663@2|Bacteria,2G70N@200795|Chloroflexi 200795|Chloroflexi S PFAM transferase hexapeptide repeat containing protein - - - - - - - - - - - - Hexapep SJTD3_k127_5022148_1 1172179.AUKV01000009_gene4534 1.766e-52 194.0 2D2DJ@1|root,32TCJ@2|Bacteria,2IKTD@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_5022148_0 1382304.JNIL01000001_gene648 1.881e-155 501.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,2786J@186823|Alicyclobacillaceae 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF_1 - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt SJTD3_k127_5022148_3 479434.Sthe_1865 4.359e-42 168.0 COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia 189775|Thermomicrobia M L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD SJTD3_k127_5022148_5 1961.JOAK01000006_gene4681 2.711e-14 87.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family bpr GO:0005575,GO:0005576 - ko:K13276 - - - - ko00000,ko01000,ko01002,ko03110 - - - CarbopepD_reg_2,CarboxypepD_reg,Inhibitor_I9,Malectin,PKD,Peptidase_M6,Peptidase_S8 SJTD3_k127_5022148_6 1123236.KB899377_gene132 1.179e-11 79.0 COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,1S45K@1236|Gammaproteobacteria,46AVX@72275|Alteromonadaceae 1236|Gammaproteobacteria S Galactose oxidase, central domain - - - - - - - - - - - - Kelch_1 SJTD3_k127_5022148_4 1347368.HG964403_gene3974 1.424e-16 95.0 COG4632@1|root,COG4632@2|Bacteria,1UWXQ@1239|Firmicutes,4HWZ4@91061|Bacilli,1ZNWY@1386|Bacillus 91061|Bacilli G S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_5022148_2 479434.Sthe_0722 7.028e-43 165.0 COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2G7EM@200795|Chloroflexi,27Z3D@189775|Thermomicrobia 189775|Thermomicrobia I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 SJTD3_k127_5025190_2 1027292.HMPREF9372_3496 2.051e-13 82.0 COG4632@1|root,COG4632@2|Bacteria,1UNIY@1239|Firmicutes,4IUFX@91061|Bacilli,26IHN@186818|Planococcaceae 91061|Bacilli G S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_5025190_4 1007104.SUS17_2735 0.0005965 53.0 COG3170@1|root,COG4932@1|root,COG3170@2|Bacteria,COG4932@2|Bacteria,1QUEG@1224|Proteobacteria 1224|Proteobacteria M Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - ko:K20276 ko02024,map02024 - - - ko00000,ko00001 - - - Big_3_2,Big_3_3 SJTD3_k127_5025190_0 1521187.JPIM01000018_gene424 4.061e-73 278.0 COG2723@1|root,COG2723@2|Bacteria,2GBIH@200795|Chloroflexi,3771Z@32061|Chloroflexia 32061|Chloroflexia G 6-phospho-beta-galactosidase activity - - - - - - - - - - - - FlaA,Glyco_hydro_42,Glyco_hydro_cc SJTD3_k127_5025190_3 485913.Krac_0023 3.702e-10 67.0 COG2909@1|root,COG2909@2|Bacteria 2|Bacteria K trisaccharide binding - - - - - - - - - - - - AAA_16,Abhydrolase_1,GerE SJTD3_k127_5025190_1 266117.Rxyl_2026 1.302e-57 208.0 COG0220@1|root,COG0220@2|Bacteria,2GJ8R@201174|Actinobacteria 201174|Actinobacteria J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 SJTD3_k127_5028877_7 765912.Thimo_1519 1.781e-06 58.0 COG0398@1|root,COG1502@1|root,COG0398@2|Bacteria,COG1502@2|Bacteria,1MV8I@1224|Proteobacteria,1RSB6@1236|Gammaproteobacteria,1WXPA@135613|Chromatiales 135613|Chromatiales I PFAM SNARE associated Golgi protein - - - - - - - - - - - - PLDc,PLDc_2,SNARE_assoc SJTD3_k127_5028877_2 644283.Micau_3155 1.344e-28 125.0 COG2220@1|root,COG2220@2|Bacteria,2GMFQ@201174|Actinobacteria,4DIXB@85008|Micromonosporales 201174|Actinobacteria S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B,Lactamase_B_2 SJTD3_k127_5028877_1 56107.Cylst_3965 1.398e-68 250.0 COG2271@1|root,COG2271@2|Bacteria,1GJ1Q@1117|Cyanobacteria,1HSWX@1161|Nostocales 1117|Cyanobacteria G Transmembrane secretion effector - - - - - - - - - - - - MFS_3 SJTD3_k127_5028877_8 1499499.EV06_1577 0.0008399 49.0 COG0170@1|root,COG0170@2|Bacteria,1GC2P@1117|Cyanobacteria,1MMFV@1212|Prochloraceae 1117|Cyanobacteria I Alternative locus ID sec59 - 2.7.1.182 ko:K18678 - - R10659 RC00002,RC00017 ko00000,ko01000 - - - - SJTD3_k127_5028877_5 642492.Clole_3975 6.704e-10 70.0 COG3153@1|root,COG3153@2|Bacteria,1VKDY@1239|Firmicutes,24X0A@186801|Clostridia 186801|Clostridia S acetyltransferase - - - - - - - - - - - - - SJTD3_k127_5028877_6 1246995.AFR_05000 7.413e-08 63.0 COG1183@1|root,COG1183@2|Bacteria,2I3MV@201174|Actinobacteria,4DA88@85008|Micromonosporales 201174|Actinobacteria I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pssA GO:0003674,GO:0003824,GO:0003882,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.8 ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 M00093 R01800 RC00002,RC00017,RC02795 ko00000,ko00001,ko00002,ko01000 - - - CDP-OH_P_tran_2,CDP-OH_P_transf SJTD3_k127_5028877_0 926560.KE387023_gene1244 1.396e-82 298.0 COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,1WM0Q@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus GT PEP-utilising enzyme, mobile domain - - - - - - - - - - - - PEP-utilizers,PPDK_N SJTD3_k127_5028877_4 1550091.JROE01000002_gene1152 2.456e-16 90.0 COG0382@1|root,COG0382@2|Bacteria,4NKPE@976|Bacteroidetes,1IW35@117747|Sphingobacteriia 976|Bacteroidetes H Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - 2.5.1.39 ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 M00117 R05000,R05615 RC00209,RC02895 ko00000,ko00001,ko00002,ko01000,ko01006 - - - UbiA SJTD3_k127_5028877_3 1123303.AQVD01000002_gene1643 2.202e-18 94.0 COG0575@1|root,COG0575@2|Bacteria,1V6V6@1239|Firmicutes 1239|Firmicutes I CDP-archaeol synthase cdsA2 - - - - - - - - - - - CarS-like SJTD3_k127_5031508_3 479434.Sthe_1905 2.55e-34 137.0 COG1307@1|root,COG1307@2|Bacteria,2G6PH@200795|Chloroflexi,27YU3@189775|Thermomicrobia 189775|Thermomicrobia S Uncharacterised protein, DegV family COG1307 - - - - - - - - - - - - DegV SJTD3_k127_5031508_2 316274.Haur_0364 3.339e-53 198.0 COG1307@1|root,COG1307@2|Bacteria,2G6P2@200795|Chloroflexi,374VJ@32061|Chloroflexia 32061|Chloroflexia S PFAM DegV family protein - - - - - - - - - - - - DegV SJTD3_k127_5031508_0 552811.Dehly_0935 1.095e-130 445.0 COG1461@1|root,COG1461@2|Bacteria,2G61Z@200795|Chloroflexi,34CPP@301297|Dehalococcoidia 301297|Dehalococcoidia S Dak1_2 - - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 SJTD3_k127_5031508_4 1128421.JAGA01000002_gene199 5.188e-25 111.0 COG1302@1|root,COG1302@2|Bacteria 2|Bacteria M Protein conserved in bacteria asp - - - - - - - - - - - Asp23 SJTD3_k127_5031508_5 255470.cbdbA1186 5.132e-13 78.0 COG0227@1|root,COG0227@2|Bacteria,2G7E5@200795|Chloroflexi,34DI9@301297|Dehalococcoidia 301297|Dehalococcoidia J Ribosomal L28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 SJTD3_k127_5031508_1 1504319.GM45_3310 3.38e-59 220.0 COG1506@1|root,COG1506@2|Bacteria 2|Bacteria E serine-type peptidase activity - - - - - - - - - - - - COesterase,DUF2920,Peptidase_S9 SJTD3_k127_5037646_0 383372.Rcas_2393 1.738e-74 268.0 COG0515@1|root,COG0515@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia 32061|Chloroflexia KLT Serine threonine protein kinase - - 2.7.11.1 ko:K08884 - - - - ko00000,ko01000,ko01001 - - - Pkinase SJTD3_k127_5037646_1 765420.OSCT_1601 3.049e-67 247.0 COG2304@1|root,COG2304@2|Bacteria,2GAE8@200795|Chloroflexi,375RK@32061|Chloroflexia 32061|Chloroflexia S PFAM von Willebrand factor type A - - - - - - - - - - - - VWA SJTD3_k127_5037646_2 383372.Rcas_4164 5.001e-25 111.0 2EE19@1|root,337W3@2|Bacteria,2G8U2@200795|Chloroflexi,375HC@32061|Chloroflexia 32061|Chloroflexia S PFAM LIM, zinc-binding protein - - - - - - - - - - - - DA1-like SJTD3_k127_5040011_3 479434.Sthe_1364 1.335e-68 239.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2G5WB@200795|Chloroflexi,27XQ3@189775|Thermomicrobia 189775|Thermomicrobia F Catalyzes the synthesis of GMP from XMP guaA - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase SJTD3_k127_5040011_6 118163.Ple7327_4181 7.189e-39 156.0 COG2267@1|root,COG2267@2|Bacteria,1GIY6@1117|Cyanobacteria,3VMFU@52604|Pleurocapsales 1117|Cyanobacteria I Alpha/beta hydrolase of unknown function (DUF1057) - - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_5040011_5 485913.Krac_8512 1.8e-40 157.0 COG4570@1|root,COG4570@2|Bacteria,2G8U7@200795|Chloroflexi 200795|Chloroflexi L Endodeoxyribonuclease RusA - - 3.1.22.4 ko:K01160 - - - - ko00000,ko01000,ko03400 - - - RusA SJTD3_k127_5040011_7 479434.Sthe_2216 1.106e-15 83.0 2A4QY@1|root,30TC8@2|Bacteria,2GA13@200795|Chloroflexi,27YI3@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - SJTD3_k127_5040011_4 1128421.JAGA01000002_gene129 1.182e-53 199.0 COG0571@1|root,COG0571@2|Bacteria,2NPCJ@2323|unclassified Bacteria 2|Bacteria J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm SJTD3_k127_5040011_1 309801.trd_1375 1.118e-137 445.0 COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,27Y4E@189775|Thermomicrobia 189775|Thermomicrobia F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) - - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N SJTD3_k127_5040011_8 1121289.JHVL01000020_gene817 2.568e-11 74.0 COG0860@1|root,COG0860@2|Bacteria,1UYPW@1239|Firmicutes,24BHU@186801|Clostridia,36HEA@31979|Clostridiaceae 186801|Clostridia M Ami_3 lytC - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,CW_binding_2,Cu_amine_oxidN1,SH3_3 SJTD3_k127_5040011_0 316274.Haur_2871 4.369e-191 609.0 COG1003@1|root,COG1003@2|Bacteria,2G5MU@200795|Chloroflexi,374WQ@32061|Chloroflexia 32061|Chloroflexia E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPB - 1.4.4.2 ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P SJTD3_k127_5040011_2 1382356.JQMP01000004_gene19 7.055e-87 294.0 COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi,27Y3Y@189775|Thermomicrobia 189775|Thermomicrobia E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P SJTD3_k127_5048628_2 118166.JH976537_gene1459 8.715e-14 76.0 COG0457@1|root,COG0457@2|Bacteria,1G5VM@1117|Cyanobacteria,1HE7X@1150|Oscillatoriales 1117|Cyanobacteria S PFAM Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8,Trypsin_2 SJTD3_k127_5048628_0 1128421.JAGA01000002_gene1162 5.475e-142 457.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - - - - - - - - - - - Epimerase SJTD3_k127_5048628_1 765420.OSCT_0914 3.655e-88 315.0 COG0457@1|root,COG2340@1|root,COG0457@2|Bacteria,COG2340@2|Bacteria,2G77P@200795|Chloroflexi,374U0@32061|Chloroflexia 32061|Chloroflexia G Domain of unknown function (DUF4380) - - - - - - - - - - - - DUF5107 SJTD3_k127_5054749_0 316274.Haur_4211 2.109e-82 290.0 COG2304@1|root,COG2304@2|Bacteria,2G82P@200795|Chloroflexi,374TF@32061|Chloroflexia 32061|Chloroflexia S PFAM von Willebrand factor type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA SJTD3_k127_5054749_1 867845.KI911784_gene3099 1.581e-41 156.0 COG0631@1|root,COG0631@2|Bacteria,2G8I1@200795|Chloroflexi,375BS@32061|Chloroflexia 32061|Chloroflexia T protein phosphatase 2C domain protein - - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 SJTD3_k127_5055665_1 203124.Tery_2398 7.882e-106 353.0 COG1304@1|root,COG1304@2|Bacteria,1G32Y@1117|Cyanobacteria,1HA70@1150|Oscillatoriales 1117|Cyanobacteria C COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid lldD - 1.1.2.3,1.1.3.46 ko:K00101,ko:K16422 ko00261,ko00620,ko01055,ko01100,ko01130,map00261,map00620,map01055,map01100,map01130 - R00196,R06633 RC00044,RC00240 ko00000,ko00001,ko01000 - - - FMN_dh SJTD3_k127_5055665_4 485913.Krac_4389 1.782e-35 142.0 COG3467@1|root,COG3467@2|Bacteria 2|Bacteria T pyridoxamine 5'-phosphate - - - ko:K05558,ko:K07005 - - - - ko00000 - - - Putative_PNPOx,Pyridox_ox_2 SJTD3_k127_5055665_3 485913.Krac_6389 3.361e-38 147.0 COG1846@1|root,COG1846@2|Bacteria,2G9BN@200795|Chloroflexi 200795|Chloroflexi K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR SJTD3_k127_5055665_0 926550.CLDAP_19050 1.103e-149 488.0 COG0160@1|root,COG0160@2|Bacteria,2G5KN@200795|Chloroflexi 200795|Chloroflexi H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.19 ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 M00027 R00908,R01648 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SJTD3_k127_5055665_2 861299.J421_4361 8.807e-50 186.0 COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,1ZTHJ@142182|Gemmatimonadetes 142182|Gemmatimonadetes K Helix-turn-helix diphteria tox regulatory element - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA SJTD3_k127_5070978_1 525904.Tter_0402 1.638e-72 258.0 COG0715@1|root,COG0715@2|Bacteria,2NQPU@2323|unclassified Bacteria 2|Bacteria P NMT1/THI5 like - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 SJTD3_k127_5070978_2 525904.Tter_0403 4.794e-62 224.0 COG0600@1|root,COG0600@2|Bacteria,2NR30@2323|unclassified Bacteria 2|Bacteria P Binding-protein-dependent transport system inner membrane component - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 SJTD3_k127_5070978_3 479434.Sthe_1244 3.188e-60 214.0 COG1259@1|root,COG1259@2|Bacteria,2G6P6@200795|Chloroflexi,27Y7W@189775|Thermomicrobia 189775|Thermomicrobia S Bifunctional nuclease - - - ko:K08999 - - - - ko00000 - - - DNase-RNase SJTD3_k127_5070978_0 335543.Sfum_2279 6.699e-136 452.0 COG1404@1|root,COG1404@2|Bacteria,1PFBD@1224|Proteobacteria,43A1G@68525|delta/epsilon subdivisions,2X9U2@28221|Deltaproteobacteria,2MSGE@213462|Syntrophobacterales 28221|Deltaproteobacteria O Subtilase family - - - - - - - - - - - - Peptidase_S8 SJTD3_k127_5071077_0 357808.RoseRS_2731 0.0 1121.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2G8BR@200795|Chloroflexi,3771M@32061|Chloroflexia 32061|Chloroflexia IQ TIGRFAM rhamnulose-1-phosphate aldolase alcohol dehydrogenase - - - - - - - - - - - - Aldolase_II,adh_short_C2 SJTD3_k127_5071077_1 1128421.JAGA01000002_gene1476 9.661e-207 650.0 COG4806@1|root,COG4806@2|Bacteria 2|Bacteria G L-rhamnose isomerase activity rhaA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575 2.7.1.5,5.3.1.14 ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 - R01902,R02437,R03014 RC00002,RC00017,RC00434 ko00000,ko00001,ko01000 - - iECIAI39_1322.ECIAI39_3092,iUMNK88_1353.UMNK88_4739 RhaA SJTD3_k127_5071077_2 485913.Krac_2561 2.575e-93 316.0 COG0524@1|root,COG0524@2|Bacteria,2G73H@200795|Chloroflexi 200795|Chloroflexi G PFAM PfkB domain protein - - 2.7.1.15,2.7.1.4 ko:K00847,ko:K00852 ko00030,ko00051,ko00500,ko00520,ko01100,map00030,map00051,map00500,map00520,map01100 - R00760,R00867,R01051,R02750,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB SJTD3_k127_5073208_1 869210.Marky_0298 2.526e-21 96.0 COG0164@1|root,COG0164@2|Bacteria,1WITM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB - 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII SJTD3_k127_5073208_2 383372.Rcas_2007 7.392e-18 88.0 COG0792@1|root,COG0792@2|Bacteria,2G7AR@200795|Chloroflexi,377JT@32061|Chloroflexia 32061|Chloroflexia L Belongs to the UPF0102 family - - - ko:K07460 - - - - ko00000 - - - UPF0102 SJTD3_k127_5073208_0 479434.Sthe_1692 4.321e-90 306.0 COG0463@1|root,COG0463@2|Bacteria,2G6TA@200795|Chloroflexi,27XT0@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_5075116_1 383372.Rcas_2466 2.032e-70 254.0 COG0517@1|root,COG0617@1|root,COG0618@1|root,COG0517@2|Bacteria,COG0617@2|Bacteria,COG0618@2|Bacteria,2G8YQ@200795|Chloroflexi,375MA@32061|Chloroflexia 32061|Chloroflexia H Polynucleotide adenylyltransferase region - - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - CBS,DHH,DHHA1,PolyA_pol,PolyA_pol_RNAbd SJTD3_k127_5075116_0 1128421.JAGA01000002_gene1934 4.379e-73 271.0 COG3664@1|root,COG3664@2|Bacteria,2NQ48@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolases family 39 - - - - - - - - - - - - Cellulase,Glyco_hydro_39,Glyco_hydro_42,Glyco_hydro_cc SJTD3_k127_5075116_2 1128421.JAGA01000002_gene1111 3.371e-37 145.0 COG0622@1|root,COG0622@2|Bacteria,2NQ04@2323|unclassified Bacteria 2|Bacteria S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 SJTD3_k127_5075116_3 243164.DET0395 3.806e-19 91.0 COG0637@1|root,COG1214@1|root,COG0637@2|Bacteria,COG1214@2|Bacteria,2G6ZZ@200795|Chloroflexi,34D2B@301297|Dehalococcoidia 301297|Dehalococcoidia O Glycoprotease family - - - - - - - - - - - - HAD_2,Peptidase_M22 SJTD3_k127_5083389_0 309801.trd_1822 6.411e-56 213.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_5083389_1 1120971.AUCA01000014_gene91 1.216e-25 114.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli 91061|Bacilli J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon SJTD3_k127_5085385_4 1123248.KB893335_gene2891 2.982e-33 139.0 COG3291@1|root,COG3386@1|root,COG3291@2|Bacteria,COG3386@2|Bacteria,4PPDU@976|Bacteroidetes 976|Bacteroidetes G Domain of unknown function (DUF5122) beta-propeller - - - - - - - - - - - - DUF5122 SJTD3_k127_5085385_2 765420.OSCT_3060 6.15e-70 243.0 COG0739@1|root,COG0739@2|Bacteria,2GADD@200795|Chloroflexi,375JT@32061|Chloroflexia 32061|Chloroflexia M Peptidase family M23 - - - - - - - - - - - - Peptidase_M23 SJTD3_k127_5085385_3 525904.Tter_0990 1.854e-49 187.0 2EBHZ@1|root,335IE@2|Bacteria 2|Bacteria S Phosphatase - - - - - - - - - - - - Phosphatase SJTD3_k127_5085385_5 926569.ANT_15630 3.027e-32 133.0 COG4720@1|root,COG4720@2|Bacteria,2G91D@200795|Chloroflexi 200795|Chloroflexi S ECF-type riboflavin transporter, S component - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS SJTD3_k127_5085385_1 383372.Rcas_1138 4.343e-113 374.0 COG5459@1|root,COG5459@2|Bacteria,2GADA@200795|Chloroflexi,375J9@32061|Chloroflexia 32061|Chloroflexia J Ribosomal small subunit Rsm22 - - - - - - - - - - - - Rsm22 SJTD3_k127_5085385_6 483219.LILAB_10650 4.482e-26 113.0 COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria 28221|Deltaproteobacteria T PFAM response regulator receiver - - - - - - - - - - - - Response_reg SJTD3_k127_5085385_0 1254432.SCE1572_46035 5.79e-150 492.0 COG0467@1|root,COG0467@2|Bacteria,1NM7E@1224|Proteobacteria,42SM2@68525|delta/epsilon subdivisions,2WPEU@28221|Deltaproteobacteria,2YXVE@29|Myxococcales 28221|Deltaproteobacteria T KaiC - - - ko:K08482 - - - - ko00000 - - - ATPase SJTD3_k127_5085385_7 1123248.KB893316_gene4596 4.596e-08 56.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,1IQ4N@117747|Sphingobacteriia 976|Bacteroidetes E Alcohol dehydrogenase GroES-like domain - - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_N_assoc,ADH_zinc_N SJTD3_k127_5102139_0 485913.Krac_10618 3.186e-62 217.0 COG0105@1|root,COG0105@2|Bacteria,2G6NP@200795|Chloroflexi 200795|Chloroflexi F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK SJTD3_k127_5102139_6 1211035.CD30_12105 2.41e-09 71.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli,3IWAP@400634|Lysinibacillus 91061|Bacilli F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135 RC00017,RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,CHB_HEX_C_1,Gram_pos_anchor,LTD,Metallophos,SLH SJTD3_k127_5102139_5 1379698.RBG1_1C00001G1377 1.521e-23 117.0 COG4409@1|root,COG4409@2|Bacteria,2NRD7@2323|unclassified Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase SJTD3_k127_5102139_4 1172188.KB911820_gene2425 2.789e-28 129.0 COG4409@1|root,COG4409@2|Bacteria,2IDDY@201174|Actinobacteria,4FH84@85021|Intrasporangiaceae 201174|Actinobacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - SJTD3_k127_5102139_2 1128421.JAGA01000002_gene1144 1.079e-48 187.0 COG0697@1|root,COG0697@2|Bacteria,2NRAW@2323|unclassified Bacteria 2|Bacteria EG EamA-like transporter family yicL_1 - - ko:K03298 - - - - ko00000,ko02000 2.A.7.3 - - EamA SJTD3_k127_5102139_1 1210884.HG799462_gene7850 3.628e-54 199.0 COG0596@1|root,COG0596@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds pcaD - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4 SJTD3_k127_5102139_7 1032480.MLP_26850 1.238e-07 64.0 2AQ5P@1|root,31FB4@2|Bacteria,2IRT0@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_5102139_3 765420.OSCT_2228 5.965e-29 120.0 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - DUF3160,YARHG,zinc_ribbon_2 SJTD3_k127_5102522_3 673860.AciM339_0816 2.754e-33 133.0 COG0110@1|root,arCOG01848@2157|Archaea,2Y65N@28890|Euryarchaeota,3F3IH@33867|unclassified Euryarchaeota 28890|Euryarchaeota S Hexapeptide repeat of succinyl-transferase - - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - Hexapep SJTD3_k127_5102522_0 326427.Cagg_1972 1.806e-126 417.0 COG0381@1|root,COG0381@2|Bacteria,2G7S6@200795|Chloroflexi,375NM@32061|Chloroflexia 32061|Chloroflexia M Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - 5.1.3.23 ko:K13019 ko00520,map00520 - R09600 RC00290 ko00000,ko00001,ko01000,ko01005 - - - Epimerase_2 SJTD3_k127_5102522_1 1031288.AXAA01000001_gene2264 9.999e-89 304.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,36E96@31979|Clostridiaceae 186801|Clostridia I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX - 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis SJTD3_k127_5102522_2 1128421.JAGA01000002_gene35 3.122e-69 245.0 COG2120@1|root,COG2120@2|Bacteria 2|Bacteria S N-acetylglucosaminylinositol deacetylase activity - - 3.5.1.115 ko:K18455 - - - - ko00000,ko01000 - - - PIG-L SJTD3_k127_5105615_7 261292.Nit79A3_0037 7.246e-35 142.0 COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,2VKHS@28216|Betaproteobacteria,373R2@32003|Nitrosomonadales 28216|Betaproteobacteria S Predicted membrane protein (DUF2254) - - - - - - - - - - - - DUF2254 SJTD3_k127_5105615_6 1304880.JAGB01000001_gene519 1.5e-49 184.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia 186801|Clostridia P domain protein ktrC - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N SJTD3_k127_5105615_4 373903.Hore_11700 6.416e-86 304.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WABA@53433|Halanaerobiales 186801|Clostridia P TIGRFAM potassium uptake protein, TrkH family ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH SJTD3_k127_5105615_0 525904.Tter_1758 6.247e-177 567.0 COG1160@1|root,COG1160@2|Bacteria,2NNTW@2323|unclassified Bacteria 2|Bacteria S GTPase that plays an essential role in the late steps of ribosome biogenesis der GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 ko:K00058,ko:K03977 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko03009,ko04147 - - - KH_dom-like,MMR_HSR1 SJTD3_k127_5105615_8 1210884.HG799462_gene9019 1.998e-19 98.0 2FDUG@1|root,345V3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5105615_2 485913.Krac_2215 1.971e-89 311.0 COG4552@1|root,COG4552@2|Bacteria,2G7MV@200795|Chloroflexi 200795|Chloroflexi S Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_9 SJTD3_k127_5105615_3 204669.Acid345_1701 5.451e-88 304.0 COG0153@1|root,COG0153@2|Bacteria,3Y300@57723|Acidobacteria,2JI7E@204432|Acidobacteriia 204432|Acidobacteriia G Belongs to the GHMP kinase family. GalK subfamily galK - 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg SJTD3_k127_5105615_1 525904.Tter_2205 3.183e-124 407.0 COG1087@1|root,COG1087@2|Bacteria,2NNVI@2323|unclassified Bacteria 2|Bacteria M NAD(P)H-binding galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd SJTD3_k127_5105615_5 1385513.N780_13725 1.808e-80 275.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli,2Y9I9@289201|Pontibacillus 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT SJTD3_k127_5111111_3 485913.Krac_9379 3.113e-17 85.0 COG2318@1|root,COG2318@2|Bacteria 2|Bacteria S DinB family - - - - - - - - - - - - DinB_2 SJTD3_k127_5111111_0 1128421.JAGA01000001_gene2210 6.343e-133 437.0 COG5441@1|root,COG5441@2|Bacteria 2|Bacteria S Uncharacterised protein family (UPF0261) - - - - - - - - - - - - UPF0261 SJTD3_k127_5111111_1 525904.Tter_0588 1.095e-86 300.0 COG0411@1|root,COG0411@2|Bacteria,2NNYG@2323|unclassified Bacteria 2|Bacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C SJTD3_k127_5111111_2 485913.Krac_8856 1.545e-39 153.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins p20 - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 SJTD3_k127_5112018_3 521098.Aaci_3061 3.487e-15 87.0 COG2133@1|root,COG2133@2|Bacteria,1UIY2@1239|Firmicutes,4HE7I@91061|Bacilli 91061|Bacilli G pyrroloquinoline quinone binding - - - - - - - - - - - - GSDH SJTD3_k127_5112018_4 1123368.AUIS01000007_gene2756 2.655e-05 53.0 COG1225@1|root,COG1225@2|Bacteria,1RD4R@1224|Proteobacteria,1RQ7F@1236|Gammaproteobacteria,2NC7J@225057|Acidithiobacillales 225057|Acidithiobacillales O Redoxin - - 1.11.1.15 ko:K03564 - - - - ko00000,ko01000 - - - AhpC-TSA SJTD3_k127_5112018_2 1089547.KB913013_gene1930 7.559e-56 200.0 COG4244@1|root,COG4244@2|Bacteria,4NPHV@976|Bacteroidetes,47PWW@768503|Cytophagia 976|Bacteroidetes S Predicted membrane protein (DUF2231) - - - - - - - - - - - - DUF2231 SJTD3_k127_5112018_1 479434.Sthe_2434 1.827e-114 381.0 COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,2G67J@200795|Chloroflexi,27XXA@189775|Thermomicrobia 189775|Thermomicrobia G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway tal - 2.2.1.2,5.3.1.9 ko:K13810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00004,M00007,M00114 R01827,R02739,R02740,R03321 RC00376,RC00439,RC00563,RC00604 ko00000,ko00001,ko00002,ko01000 - - - PGI,TAL_FSA SJTD3_k127_5112018_0 221288.JH992900_gene317 7.411e-168 535.0 COG3387@1|root,COG3387@2|Bacteria,1G3RH@1117|Cyanobacteria,1JKJ5@1189|Stigonemataceae 1117|Cyanobacteria G Glucodextranase, domain N - - 3.2.1.3 ko:K01178 ko00500,ko01100,map00500,map01100 - R01790,R01791,R06199 - ko00000,ko00001,ko01000 - GH15 - Glucodextran_N,Glyco_hydro_15 SJTD3_k127_5115671_0 118161.KB235922_gene2046 1.356e-118 397.0 COG0769@1|root,COG1181@1|root,COG0769@2|Bacteria,COG1181@2|Bacteria,1G141@1117|Cyanobacteria,3VIRQ@52604|Pleurocapsales 1117|Cyanobacteria M Mur ligase family, glutamate ligase domain cphA - 6.3.2.29,6.3.2.30 ko:K03802 - - - - ko00000,ko01000 - - - Mur_ligase_C,Mur_ligase_M,RimK SJTD3_k127_5115671_1 570952.ATVH01000015_gene1481 6.014e-44 171.0 COG4242@1|root,COG4242@2|Bacteria,1PR9J@1224|Proteobacteria,2U4I8@28211|Alphaproteobacteria,2JVEW@204441|Rhodospirillales 204441|Rhodospirillales PQ Peptidase family S51 - - - - - - - - - - - - Peptidase_S51 SJTD3_k127_5116649_1 545696.HOLDEFILI_02796 3.165e-70 250.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,3VNTS@526524|Erysipelotrichia 526524|Erysipelotrichia M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_5116649_2 926554.KI912668_gene5111 5.376e-61 213.0 COG0662@1|root,COG0662@2|Bacteria 2|Bacteria G Cupin 2, conserved barrel domain protein - - - - - - - - - - - - FdtA SJTD3_k127_5116649_0 477974.Daud_1700 6.274e-90 302.0 COG1043@1|root,COG1043@2|Bacteria,1UKN8@1239|Firmicutes,25FZU@186801|Clostridia 186801|Clostridia M Hexapeptide repeat of succinyl-transferase - - - - - - - - - - - - Hexapep SJTD3_k127_5117014_3 1279009.ADICEAN_03023 7.569e-12 79.0 COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NG09@976|Bacteroidetes,47NP4@768503|Cytophagia 976|Bacteroidetes S Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,PKD,Peptidase_M36 SJTD3_k127_5117014_2 227086.JGI_V11_91212 9.671e-15 88.0 KOG4441@1|root,KOG4441@2759|Eukaryota 2759|Eukaryota KLT protein ubiquitination - - - ko:K10442,ko:K10443,ko:K10447 ko04120,map04120 - - - ko00000,ko00001,ko04121 - - - BACK,BTB,Kelch_1 SJTD3_k127_5117014_0 1499968.TCA2_5469 5.619e-25 113.0 COG0526@1|root,COG0526@2|Bacteria,1VMQ5@1239|Firmicutes,4HSAG@91061|Bacilli,2712P@186822|Paenibacillaceae 91061|Bacilli CO COG0526, thiol-disulfide isomerase and thioredoxins - - - - - - - - - - - - Thioredoxin_2 SJTD3_k127_5117014_1 398512.JQKC01000014_gene1647 1.568e-18 98.0 COG2866@1|root,COG3266@1|root,COG5184@1|root,COG2866@2|Bacteria,COG3266@2|Bacteria,COG5184@2|Bacteria,1UK10@1239|Firmicutes,24MM4@186801|Clostridia,3WPC9@541000|Ruminococcaceae 186801|Clostridia E S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_5131755_2 765420.OSCT_0993 1.225e-61 213.0 COG4799@1|root,COG4799@2|Bacteria,2G61R@200795|Chloroflexi,3767V@32061|Chloroflexia 32061|Chloroflexia I PFAM carboxyl transferase - - 2.1.3.15,6.4.1.3 ko:K15052 ko00720,ko01200,map00720,map01200 M00376 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans SJTD3_k127_5131755_1 1128421.JAGA01000002_gene1141 6.055e-83 283.0 COG1024@1|root,COG1024@2|Bacteria,2NR3A@2323|unclassified Bacteria 2|Bacteria I Enoyl-CoA hydratase/isomerase atuE - 4.2.1.18,4.2.1.57 ko:K13766,ko:K13779 ko00280,ko00281,ko01100,map00280,map00281,map01100 M00036 R02085,R03493 RC00941,RC02416 ko00000,ko00001,ko00002,ko01000 - - - ECH_1 SJTD3_k127_5131755_0 1128421.JAGA01000002_gene1149 4.991e-179 584.0 COG4770@1|root,COG4770@2|Bacteria 2|Bacteria I CoA carboxylase activity - - 6.4.1.4 ko:K01968 ko00280,ko01100,map00280,map01100 M00036 R04138 RC00367,RC00942 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2 SJTD3_k127_5131755_3 485913.Krac_6815 3.078e-55 199.0 COG0119@1|root,COG0119@2|Bacteria,2G7M0@200795|Chloroflexi 200795|Chloroflexi E PFAM pyruvate carboxyltransferase - - 4.1.3.4 ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 M00036,M00088 R01360,R08090 RC00502,RC00503,RC01118,RC01946 ko00000,ko00001,ko00002,ko01000 - - - HMGL-like SJTD3_k127_5132565_1 675635.Psed_0410 8.802e-60 219.0 COG0265@1|root,COG0265@2|Bacteria,2IG6N@201174|Actinobacteria 201174|Actinobacteria O Trypsin-like peptidase domain - - - - - - - - - - - - Trypsin_2 SJTD3_k127_5132565_0 296591.Bpro_3891 2.708e-102 336.0 COG0714@1|root,COG0714@2|Bacteria,1MUFN@1224|Proteobacteria,2VKJJ@28216|Betaproteobacteria,4AD31@80864|Comamonadaceae 28216|Betaproteobacteria S ATPase associated with various cellular activities, AAA_3 - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SJTD3_k127_5133508_2 227882.SAV_432 6.798e-20 91.0 COG3210@1|root,COG3210@2|Bacteria,2I4P8@201174|Actinobacteria 201174|Actinobacteria U Right handed beta helix region - - - - - - - - - - - - Beta_helix SJTD3_k127_5133508_3 383372.Rcas_0309 1.401e-17 89.0 2EJQK@1|root,33DFE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5133508_0 1133849.O3I_011900 7.605e-84 286.0 COG2267@1|root,COG2267@2|Bacteria,2I5HD@201174|Actinobacteria,4FZ1V@85025|Nocardiaceae 201174|Actinobacteria I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 SJTD3_k127_5133508_1 1267535.KB906767_gene646 7.104e-31 123.0 COG5552@1|root,COG5552@2|Bacteria 2|Bacteria S Uncharacterized conserved protein (DUF2277) MA20_01405 - - - - - - - - - - - DUF2277 SJTD3_k127_5134104_2 1242864.D187_002561 2.052e-14 79.0 COG0745@1|root,COG0745@2|Bacteria,1NBDV@1224|Proteobacteria,42UVC@68525|delta/epsilon subdivisions,2WQ45@28221|Deltaproteobacteria 28221|Deltaproteobacteria T PFAM response regulator receiver - - - - - - - - - - - - Response_reg SJTD3_k127_5134104_1 1148.1652968 1.471e-18 90.0 COG0642@1|root,COG0784@1|root,COG2198@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2198@2|Bacteria,COG2205@2|Bacteria,COG3706@2|Bacteria,1G09B@1117|Cyanobacteria,1H6W3@1142|Synechocystis 1117|Cyanobacteria T Histidine Phosphotransfer domain - - 2.7.13.3 ko:K11527 - - - - ko00000,ko01000,ko01001,ko02022 - - - GAF,HATPase_c,HisKA,Hpt,PAS,PAS_9,Response_reg SJTD3_k127_5134104_0 937777.Deipe_2571 7.039e-42 157.0 COG1286@1|root,COG2340@1|root,COG1286@2|Bacteria,COG2340@2|Bacteria,1WK37@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S protein with SCP PR1 domains - - - - - - - - - - - - CAP SJTD3_k127_5139952_0 398767.Glov_3213 3.401e-14 87.0 COG0457@1|root,COG0457@2|Bacteria,1PEPM@1224|Proteobacteria,42Y8V@68525|delta/epsilon subdivisions,2WU79@28221|Deltaproteobacteria,43TE3@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_11,TPR_16,TPR_19,TPR_8 SJTD3_k127_5148311_2 1382356.JQMP01000004_gene272 0.0001028 45.0 COG1173@1|root,COG1173@2|Bacteria,2G63I@200795|Chloroflexi,27XQD@189775|Thermomicrobia 189775|Thermomicrobia EP N-terminal TM domain of oligopeptide transport permease C - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N SJTD3_k127_5148311_0 670487.Ocepr_1706 2.221e-47 185.0 COG0601@1|root,COG0601@2|Bacteria,1WIUD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EP ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 SJTD3_k127_5148311_1 357808.RoseRS_3760 5.429e-40 162.0 COG1287@1|root,COG1287@2|Bacteria,2GANB@200795|Chloroflexi,376UI@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_5161950_0 246194.CHY_2323 9.104e-64 222.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,42G61@68295|Thermoanaerobacterales 186801|Clostridia J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK - - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N SJTD3_k127_5161950_1 869210.Marky_1921 6.925e-39 150.0 COG0517@1|root,COG5485@1|root,COG0517@2|Bacteria,COG5485@2|Bacteria,1WK3F@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Domain in cystathionine beta-synthase and other proteins. - - - - - - - - - - - - CBS SJTD3_k127_5161950_2 1444309.JAQG01000031_gene2863 4.053e-24 112.0 COG0500@1|root,COG2226@2|Bacteria,1U9IT@1239|Firmicutes,4HDV5@91061|Bacilli,270FZ@186822|Paenibacillaceae 91061|Bacilli Q ubiE/COQ5 methyltransferase family rebM - - - - - - - - - - - Methyltransf_11 SJTD3_k127_5175716_1 649831.L083_1974 2.55e-05 57.0 COG5305@1|root,COG5305@2|Bacteria,2GN7C@201174|Actinobacteria,4DAG7@85008|Micromonosporales 201174|Actinobacteria S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - ko:K14340 - - - - ko00000,ko01000,ko01003 - - - PMT_2 SJTD3_k127_5175716_0 338963.Pcar_0624 3.24e-104 357.0 COG2133@1|root,COG2133@2|Bacteria,1MVK5@1224|Proteobacteria,42MU3@68525|delta/epsilon subdivisions,2WKTF@28221|Deltaproteobacteria,43SSU@69541|Desulfuromonadales 28221|Deltaproteobacteria G Glucose / Sorbosone dehydrogenase - - - - - - - - - - - - GSDH SJTD3_k127_5177673_2 765420.OSCT_0366 3.088e-08 57.0 COG0135@1|root,COG0135@2|Bacteria,2G6QB@200795|Chloroflexi,375IK@32061|Chloroflexia 32061|Chloroflexia E Belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI SJTD3_k127_5177673_1 1120973.AQXL01000134_gene1549 8.029e-65 231.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HDZQ@91061|Bacilli,2789J@186823|Alicyclobacillaceae 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508,R03509 RC00944,RC00945 ko00000,ko00001,ko00002,ko01000 - - - IGPS SJTD3_k127_5177673_0 1382356.JQMP01000004_gene440 8.239e-112 373.0 COG0547@1|root,COG0547@2|Bacteria,2G5YV@200795|Chloroflexi,27XT8@189775|Thermomicrobia 189775|Thermomicrobia F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD - 2.4.2.18 ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R01073 RC00440 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 SJTD3_k127_5178897_2 760192.Halhy_1763 2.929e-95 325.0 COG0457@1|root,COG2319@1|root,COG0457@2|Bacteria,COG2319@2|Bacteria,4NH20@976|Bacteroidetes,1IQXJ@117747|Sphingobacteriia 976|Bacteroidetes B PFAM WD domain, G-beta repeat - - - - - - - - - - - - WD40 SJTD3_k127_5178897_8 408672.NBCG_00755 1.686e-21 99.0 COG3324@1|root,COG3324@2|Bacteria,2HUGD@201174|Actinobacteria,4DSW3@85009|Propionibacteriales 201174|Actinobacteria S Glyoxalase-like domain - - - ko:K06996 - - - - ko00000 - - - Glyoxalase SJTD3_k127_5178897_6 272123.Anacy_2815 3.002e-43 168.0 2957S@1|root,2ZSK8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5178897_7 383372.Rcas_3427 6.081e-34 140.0 COG0664@1|root,COG0664@2|Bacteria,2G6XU@200795|Chloroflexi,375MJ@32061|Chloroflexia 32061|Chloroflexia K PFAM cyclic nucleotide-binding - - - ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 - - - ko00000,ko00001,ko03000 - - - HTH_Crp_2,cNMP_binding SJTD3_k127_5178897_5 247490.KSU1_D0846 1.633e-47 175.0 2B5RU@1|root,31YMF@2|Bacteria,2J42A@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - SJTD3_k127_5178897_4 1379698.RBG1_1C00001G1800 3.597e-48 184.0 arCOG11509@1|root,31KIR@2|Bacteria,2NR0T@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5178897_3 1274524.BSONL12_17404 6.075e-55 195.0 COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli,1ZHFW@1386|Bacillus 91061|Bacilli E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily ywkD - - ko:K08234 - - - - ko00000 - - - Glyoxalase SJTD3_k127_5178897_0 765420.OSCT_2079 8.444e-179 575.0 COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,2G64U@200795|Chloroflexi,374ZG@32061|Chloroflexia 32061|Chloroflexia P YidE YbjL duplication domain protein - - - ko:K07085 - - - - ko00000 2.A.81 - - Asp-Al_Ex,TrkA_C SJTD3_k127_5178897_1 926550.CLDAP_21610 5.33e-101 336.0 COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi 200795|Chloroflexi I PFAM carboxyl transferase - - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans SJTD3_k127_5185569_1 316274.Haur_0437 6.421e-21 106.0 COG3227@1|root,COG3227@2|Bacteria,2G8C6@200795|Chloroflexi,377AX@32061|Chloroflexia 32061|Chloroflexia E PFAM peptidase M4 thermolysin - - - - - - - - - - - - FTP,Peptidase_M4,Peptidase_M4_C SJTD3_k127_5185569_2 1243664.CAVL020000028_gene102 2.742e-19 101.0 COG1404@1|root,COG3103@1|root,COG5492@1|root,COG1404@2|Bacteria,COG3103@2|Bacteria,COG5492@2|Bacteria 2|Bacteria N domain, Protein - - - - - - - - - - - - Peptidase_M43,Reprolysin_4,SH3_3,SLH,fn3 SJTD3_k127_5185569_0 1128421.JAGA01000003_gene2823 2.423e-47 177.0 COG2606@1|root,COG2606@2|Bacteria,2NPZ1@2323|unclassified Bacteria 2|Bacteria S Aminoacyl-tRNA editing domain - - - ko:K19055 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit SJTD3_k127_5193869_2 309801.trd_1718 5.517e-81 284.0 COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2G5WG@200795|Chloroflexi,27XRJ@189775|Thermomicrobia 189775|Thermomicrobia S Belongs to the peptidase M50B family - - - - - - - - - - - - CBS,Peptidase_M50 SJTD3_k127_5193869_4 696281.Desru_3277 8.733e-54 201.0 COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,261JW@186807|Peptococcaceae 186801|Clostridia EG PFAM EamA-like transporter family - - - - - - - - - - - - EamA SJTD3_k127_5193869_1 479434.Sthe_0406 4.556e-86 308.0 COG4974@1|root,COG4974@2|Bacteria,2G6QW@200795|Chloroflexi,27Y2K@189775|Thermomicrobia 189775|Thermomicrobia L Belongs to the 'phage' integrase family - - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_integrase SJTD3_k127_5193869_3 546274.EIKCOROL_01177 1.996e-65 231.0 28NPX@1|root,2ZBPN@2|Bacteria,1RD56@1224|Proteobacteria,2VSRQ@28216|Betaproteobacteria,2KSNG@206351|Neisseriales 206351|Neisseriales S Protein of unknown function DUF2625 - - - - - - - - - - - - DUF2625 SJTD3_k127_5193869_5 1121382.JQKG01000010_gene4704 6.811e-44 170.0 COG0645@1|root,COG0645@2|Bacteria 2|Bacteria S AAA domain - - - - - - - - - - - - AAA_18,AAA_33,CPT SJTD3_k127_5193869_0 1127134.NOCYR_3452 3.477e-93 319.0 COG2197@1|root,COG2197@2|Bacteria,2GPKD@201174|Actinobacteria,4FYKY@85025|Nocardiaceae 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - GAF,GerE SJTD3_k127_5193869_8 314345.SPV1_02512 2.94e-23 104.0 COG5485@1|root,COG5485@2|Bacteria 2|Bacteria S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL SJTD3_k127_5193869_7 1210884.HG799462_gene9019 5.762e-34 140.0 2FDUG@1|root,345V3@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5193869_9 697284.ERIC2_c34260 8.004e-11 63.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli,26Y6J@186822|Paenibacillaceae 91061|Bacilli S thioesterase yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 SJTD3_k127_5197112_0 525904.Tter_0669 8.264e-268 842.0 COG1404@1|root,COG1404@2|Bacteria,2NQYY@2323|unclassified Bacteria 2|Bacteria O PA domain - - - - - - - - - - - - He_PIG,Inhibitor_I9,PA,Peptidase_S8 SJTD3_k127_5197112_1 1128421.JAGA01000003_gene3304 5.641e-68 242.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi SJTD3_k127_5228248_0 485913.Krac_11199 0.0 1412.0 COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2G5Y6@200795|Chloroflexi 200795|Chloroflexi H Methionine synthase B12-binding module cap domain protein - - 2.1.1.13,2.1.1.258 ko:K00548,ko:K15023 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230 M00017,M00377 R00946,R02289,R09365,R10243 RC00004,RC00035,RC00113,RC01144,RC01241,RC02871,RC02977 ko00000,ko00001,ko00002,ko01000 - - - B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans SJTD3_k127_5233059_3 765420.OSCT_0805 1.647e-56 201.0 COG0577@1|root,COG0577@2|Bacteria,2G65B@200795|Chloroflexi,37660@32061|Chloroflexia 32061|Chloroflexia V MacB-like periplasmic core domain - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SJTD3_k127_5233059_5 1123013.AUIC01000002_gene1013 0.0006078 51.0 2B25G@1|root,31UNQ@2|Bacteria,2H1A0@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_5233059_2 1123073.KB899241_gene2268 3.311e-63 227.0 arCOG08211@1|root,2ZBM3@2|Bacteria,1RIRV@1224|Proteobacteria,1SFXN@1236|Gammaproteobacteria,1X59H@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SJTD3_k127_5233059_0 1128421.JAGA01000001_gene2242 9.812e-95 325.0 COG0577@1|root,COG0577@2|Bacteria 2|Bacteria V efflux transmembrane transporter activity ytrF - - ko:K02004,ko:K16918 ko02010,map02010 M00258,M00584 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SJTD3_k127_5233059_1 1128421.JAGA01000001_gene2241 7.586e-82 279.0 COG1136@1|root,COG1136@2|Bacteria,2NP53@2323|unclassified Bacteria 2|Bacteria V ABC transporter - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_5233059_4 1128421.JAGA01000001_gene2240 0.000182 49.0 COG2834@1|root,COG2834@2|Bacteria 2|Bacteria M Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - - - - - - - - - - Cadherin,DUF285,LolA,MucB_RseB,NHL SJTD3_k127_523487_2 525378.HMPREF0793_0097 5.708e-16 81.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli,4GZ7E@90964|Staphylococcaceae 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB SJTD3_k127_523487_1 1144275.COCOR_05100 1.437e-22 103.0 COG0745@1|root,COG0745@2|Bacteria,1NEVF@1224|Proteobacteria,43C0G@68525|delta/epsilon subdivisions,2WY70@28221|Deltaproteobacteria 28221|Deltaproteobacteria T cheY-homologous receiver domain - - - - - - - - - - - - Response_reg SJTD3_k127_523487_0 1047013.AQSP01000131_gene1797 2.984e-26 123.0 COG0823@1|root,COG0823@2|Bacteria,2NPHZ@2323|unclassified Bacteria 2|Bacteria U WD40-like Beta Propeller Repeat - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 SJTD3_k127_5240598_0 1128421.JAGA01000003_gene3677 4.206e-113 377.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family aprX - - ko:K17734 - - - - ko00000,ko01000,ko01002 - - - Peptidase_S8 SJTD3_k127_5240598_1 768706.Desor_5366 2.241e-54 218.0 COG2206@1|root,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia,260SG@186807|Peptococcaceae 186801|Clostridia T PFAM HD domain - - - - - - - - - - - - HD,HD_5 SJTD3_k127_5240598_2 215803.DB30_5187 2.361e-27 121.0 28WH1@1|root,2ZIH5@2|Bacteria,1Q9SQ@1224|Proteobacteria,439G6@68525|delta/epsilon subdivisions,2X4S4@28221|Deltaproteobacteria,2YZH4@29|Myxococcales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_524536_0 383372.Rcas_3885 0.0001945 52.0 COG1287@1|root,COG1287@2|Bacteria,2GA8N@200795|Chloroflexi,374X5@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_5245536_5 398767.Glov_0941 6.125e-05 48.0 COG1826@1|root,COG1826@2|Bacteria 2|Bacteria U protein secretion tatA - - ko:K03116 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 SJTD3_k127_5245536_2 644966.Tmar_2017 5.939e-43 171.0 COG0859@1|root,COG0859@2|Bacteria,1TRN2@1239|Firmicutes,25DGT@186801|Clostridia 186801|Clostridia H PFAM Glycosyltransferase family 9 (heptosyltransferase) - - - - - - - - - - - - Glyco_transf_9 SJTD3_k127_5245536_3 1521187.JPIM01000053_gene2945 4.111e-23 101.0 2EMHG@1|root,33F64@2|Bacteria,2G7IC@200795|Chloroflexi,375VD@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_5245536_0 1128421.JAGA01000002_gene179 6.518e-209 674.0 COG0515@1|root,COG1520@1|root,COG0515@2|Bacteria,COG1520@2|Bacteria,2NQ6A@2323|unclassified Bacteria 2|Bacteria KLT PQQ enzyme repeat - - 2.7.11.1 ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PQQ_2,PQQ_3,Pkinase SJTD3_k127_5245536_1 357808.RoseRS_2149 2.022e-48 184.0 COG0681@1|root,COG0681@2|Bacteria,2G701@200795|Chloroflexi,375E7@32061|Chloroflexia 32061|Chloroflexia U Belongs to the peptidase S26 family - - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24 SJTD3_k127_5245536_4 373903.Hore_19170 7.359e-11 72.0 COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,24M7G@186801|Clostridia 186801|Clostridia S PFAM GCN5-related N-acetyltransferase - - - ko:K06976 - - - - ko00000 - - - Acetyltransf_1,GNAT_acetyltran SJTD3_k127_5248802_0 748449.Halha_1833 2.127e-61 230.0 COG3408@1|root,COG3408@2|Bacteria 2|Bacteria G Glycogen debranching enzyme - - 3.2.1.40 ko:K05989 - - - - ko00000,ko01000 - - - Bac_rhamnosid6H,Bac_rhamnosid_C,GDE_C SJTD3_k127_5248802_1 1123386.AUIW01000002_gene1160 6.536e-45 178.0 COG1609@1|root,COG1609@2|Bacteria,1WM4T@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus K Bacterial regulatory proteins, lacI family - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 SJTD3_k127_5252218_2 1128421.JAGA01000003_gene2755 3.538e-05 47.0 COG2723@1|root,COG2723@2|Bacteria 2|Bacteria G beta-glucosidase activity - - 3.2.1.21 ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - - - Glyco_hydro_1 SJTD3_k127_5252218_0 926569.ANT_30290 8.482e-109 362.0 COG0457@1|root,COG0457@2|Bacteria,2G76G@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4037) - - - - - - - - - - - - DUF4037 SJTD3_k127_5252218_1 204669.Acid345_1701 9.99e-34 133.0 COG0153@1|root,COG0153@2|Bacteria,3Y300@57723|Acidobacteria,2JI7E@204432|Acidobacteriia 204432|Acidobacteriia G Belongs to the GHMP kinase family. GalK subfamily galK - 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg SJTD3_k127_5258341_2 221288.JH992901_gene5299 9.294e-17 91.0 2B0GJ@1|root,31SU3@2|Bacteria,1G4WP@1117|Cyanobacteria,1JMK7@1189|Stigonemataceae 1117|Cyanobacteria - - - - - - - - - - - - - - - SJTD3_k127_5258341_1 1121405.dsmv_3690 1.901e-112 395.0 COG4447@1|root,COG4447@2|Bacteria,1P209@1224|Proteobacteria 1224|Proteobacteria S cellulose binding - - - - - - - - - - - - - SJTD3_k127_5258341_3 1151119.KB895507_gene200 1.193e-09 72.0 COG5479@1|root,COG5479@2|Bacteria 2|Bacteria M isomerase activity - - - - - - - - - - - - LGFP,VCBS SJTD3_k127_5258341_0 211165.AJLN01000148_gene2383 3.407e-118 387.0 COG2303@1|root,COG2303@2|Bacteria,1G5DG@1117|Cyanobacteria,1JJC1@1189|Stigonemataceae 1117|Cyanobacteria E GMC oxidoreductase - - 1.1.3.6 ko:K03333 ko00984,ko01120,map00984,map01120 - R01459 RC00146 ko00000,ko00001,ko01000 - - - GMC_oxred_C,GMC_oxred_N SJTD3_k127_5273966_1 1303518.CCALI_02333 4.905e-89 306.0 COG1873@1|root,COG2239@1|root,COG1873@2|Bacteria,COG2239@2|Bacteria 2|Bacteria P Acts as a magnesium transporter - - - ko:K03886 ko00190,ko01100,map00190,map01100 M00151 - - ko00000,ko00001,ko00002,ko01000 - - - CBS,DUF2171,MgtE_N,PRC SJTD3_k127_5273966_2 351160.RCIX947 2.562e-35 143.0 COG1926@1|root,arCOG00041@2157|Archaea,2XWHP@28890|Euryarchaeota,2N9V9@224756|Methanomicrobia 224756|Methanomicrobia F Phosphoribosyl transferase domain - - - - - - - - - - - - Pribosyltran SJTD3_k127_5273966_3 383372.Rcas_0309 5.909e-10 65.0 2EJQK@1|root,33DFE@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5273966_0 1172188.KB911829_gene4456 2.998e-118 396.0 COG4409@1|root,COG4409@2|Bacteria,2IEMG@201174|Actinobacteria,4FITI@85021|Intrasporangiaceae 201174|Actinobacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - SJTD3_k127_5275940_1 479434.Sthe_0786 1.873e-30 124.0 COG0537@1|root,COG0537@2|Bacteria,2G6VV@200795|Chloroflexi,27YE1@189775|Thermomicrobia 189775|Thermomicrobia FG Scavenger mRNA decapping enzyme C-term binding - - - ko:K02503 - - - - ko00000,ko04147 - - - HIT SJTD3_k127_5275940_3 1341695.BBOMB_0544 0.0001478 54.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CYTR@85004|Bifidobacteriales 201174|Actinobacteria KLT PASTA pknL GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase SJTD3_k127_5275940_0 525904.Tter_1735 9.743e-168 562.0 COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,2NQSS@2323|unclassified Bacteria 2|Bacteria S Putative glutamine amidotransferase - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,GATase1_like,VWA,VWA_2,VWA_3 SJTD3_k127_5275940_2 317619.ANKN01000152_gene1855 1.481e-21 111.0 COG0668@1|root,COG0668@2|Bacteria,1G3HW@1117|Cyanobacteria 1117|Cyanobacteria M PFAM Mechanosensitive ion channel - - - ko:K16052 - - - - ko00000,ko02000 1.A.23.4 - - MS_channel SJTD3_k127_527828_1 926569.ANT_14860 1.338e-14 74.0 COG1167@1|root,COG1167@2|Bacteria,2G61E@200795|Chloroflexi 200795|Chloroflexi EK PFAM Aminotransferase class I and II - - - ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 - R01939 RC00006 ko00000,ko00001,ko01000 - - - Aminotran_1_2 SJTD3_k127_527828_0 1382356.JQMP01000003_gene1664 4.545e-37 159.0 COG5309@1|root,COG5309@2|Bacteria,2G8VX@200795|Chloroflexi,27XUZ@189775|Thermomicrobia 189775|Thermomicrobia G Glycosyl hydrolase catalytic core - - - - - - - - - - - - Glyco_hydro_cc SJTD3_k127_5278327_0 316274.Haur_4809 3.038e-85 292.0 COG1192@1|root,COG1192@2|Bacteria,2G62U@200795|Chloroflexi,374YK@32061|Chloroflexia 32061|Chloroflexia D PFAM Cobyrinic acid a,c-diamide synthase - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 SJTD3_k127_5278327_2 1396418.BATQ01000015_gene4317 8.401e-42 169.0 COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia,2IUEA@203494|Verrucomicrobiae 203494|Verrucomicrobiae S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes larC - 4.99.1.12 ko:K09121 - - - - ko00000,ko01000 - - - DUF111 SJTD3_k127_5278327_1 357808.RoseRS_1889 8.56e-82 284.0 COG1721@1|root,COG1721@2|Bacteria,2GACI@200795|Chloroflexi,375AS@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 SJTD3_k127_5281288_1 1128421.JAGA01000001_gene2184 2.773e-73 260.0 COG1082@1|root,COG1082@2|Bacteria,2NQSY@2323|unclassified Bacteria 2|Bacteria G Xylose isomerase-like TIM barrel iolE - - - - - - - - - - - AP_endonuc_2 SJTD3_k127_5281288_0 1304880.JAGB01000002_gene2262 1.564e-148 476.0 COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,249UF@186801|Clostridia 186801|Clostridia E PFAM oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA SJTD3_k127_5285270_0 357808.RoseRS_0659 1.41e-201 662.0 COG0457@1|root,COG5427@1|root,COG0457@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,37551@32061|Chloroflexia 32061|Chloroflexia M Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - DUF2298,PMT_2,TPR_16,TPR_19,TPR_8 SJTD3_k127_5285270_1 357808.RoseRS_0779 1.058e-79 291.0 COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,377RQ@32061|Chloroflexia 32061|Chloroflexia M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_5285617_2 292459.STH750 5.94e-21 95.0 COG0745@1|root,COG0745@2|Bacteria,1TPWS@1239|Firmicutes,25AZ2@186801|Clostridia 186801|Clostridia K response regulator receiver phoP - - ko:K02483,ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SJTD3_k127_5285617_0 1210884.HG799471_gene14698 3.764e-84 286.0 COG0500@1|root,COG0500@2|Bacteria,2J54N@203682|Planctomycetes 203682|Planctomycetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_5285617_1 706587.Desti_1672 1.051e-41 167.0 COG0432@1|root,COG0432@2|Bacteria,1N5SN@1224|Proteobacteria,42SJC@68525|delta/epsilon subdivisions,2WP9F@28221|Deltaproteobacteria,2MRXI@213462|Syntrophobacterales 28221|Deltaproteobacteria S Uncharacterised protein family UPF0047 - - - - - - - - - - - - UPF0047 SJTD3_k127_5285617_4 644966.Tmar_1450 2.049e-14 83.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,3WDB4@538999|Clostridiales incertae sedis 186801|Clostridia E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA SJTD3_k127_5285617_3 765420.OSCT_1965 9.105e-15 83.0 COG5022@1|root,COG5022@2|Bacteria,2GBHX@200795|Chloroflexi,37800@32061|Chloroflexia 32061|Chloroflexia Z LysM domain - - - - - - - - - - - - - SJTD3_k127_529650_3 479434.Sthe_3033 6.37e-31 124.0 COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi 200795|Chloroflexi Q PFAM Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_31 SJTD3_k127_529650_6 479434.Sthe_3033 4.47e-12 67.0 COG0500@1|root,COG2226@2|Bacteria,2G8IB@200795|Chloroflexi 200795|Chloroflexi Q PFAM Methyltransferase type 12 - - - - - - - - - - - - Methyltransf_31 SJTD3_k127_529650_7 935866.JAER01000002_gene1913 3.464e-05 57.0 COG3427@1|root,COG3427@2|Bacteria,2IK4M@201174|Actinobacteria,4DV38@85009|Propionibacteriales 201174|Actinobacteria S Polyketide cyclase / dehydrase and lipid transport - - - - - - - - - - - - Polyketide_cyc2 SJTD3_k127_529650_0 485913.Krac_2372 1.911e-104 351.0 2DBVK@1|root,2ZBBH@2|Bacteria,2G7SF@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - SJTD3_k127_529650_5 903818.KI912268_gene2810 3.489e-13 85.0 COG3210@1|root,COG4412@1|root,COG3210@2|Bacteria,COG4412@2|Bacteria 2|Bacteria S peptidase activity, acting on L-amino acid peptides - - - ko:K20276,ko:K21449 ko02024,map02024 - - - ko00000,ko00001,ko02000 1.B.40.2 - - Big_2,CARDB,Cadherin-like,Peptidase_M30,SLH,fn3 SJTD3_k127_529650_1 927677.ALVU02000001_gene4390 1.334e-96 358.0 COG3227@1|root,COG3227@2|Bacteria,1G3KW@1117|Cyanobacteria 1117|Cyanobacteria E PFAM Thermolysin metallopeptidase, alpha-helical domain - - - - - - - - - - - - FTP,Peptidase_M4,Peptidase_M4_C SJTD3_k127_529650_4 608538.HTH_1380 9.405e-20 106.0 COG3210@1|root,COG3227@1|root,COG3210@2|Bacteria,COG3227@2|Bacteria 2|Bacteria E Zinc metalloprotease (Elastase) - - 3.2.1.18,3.4.11.10 ko:K01186,ko:K05994,ko:K21449 ko00511,ko00600,ko04142,map00511,map00600,map04142 - R04018 RC00028,RC00077 ko00000,ko00001,ko01000,ko01002,ko02000,ko02042 1.B.40.2 GH33 - Beta_helix,PKD,Peptidase_S74,fn3 SJTD3_k127_5298342_0 2074.JNYD01000001_gene6280 5.378e-81 279.0 COG1541@1|root,COG1541@2|Bacteria,2HQ5P@201174|Actinobacteria,4E8WV@85010|Pseudonocardiales 201174|Actinobacteria H Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - - - - - - - - - - AMP-binding SJTD3_k127_5303880_0 344747.PM8797T_09989 1.084e-88 302.0 COG0500@1|root,COG2226@2|Bacteria,2J0NE@203682|Planctomycetes 203682|Planctomycetes Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_5303880_1 316274.Haur_3265 1.28e-38 152.0 COG1404@1|root,COG4412@1|root,COG1404@2|Bacteria,COG4412@2|Bacteria,2G7HM@200795|Chloroflexi,375CA@32061|Chloroflexia 32061|Chloroflexia M PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - - - - - - - - - - Peptidase_S8 SJTD3_k127_5307679_0 383372.Rcas_3163 4.474e-59 209.0 COG1024@1|root,COG1024@2|Bacteria,2G5JW@200795|Chloroflexi,37631@32061|Chloroflexia 32061|Chloroflexia I PFAM Enoyl-CoA hydratase isomerase - - 4.2.1.17 ko:K01715 ko00650,ko01200,map00650,map01200 - R03026 RC00831 ko00000,ko00001,ko01000 - - - ECH_1 SJTD3_k127_5307679_1 1382306.JNIM01000001_gene3668 3.672e-18 96.0 COG0454@1|root,COG0456@2|Bacteria,2G9G9@200795|Chloroflexi 200795|Chloroflexi K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_5313663_1 1128421.JAGA01000003_gene3434 6.015e-125 404.0 COG0451@1|root,COG0451@2|Bacteria,2NQI1@2323|unclassified Bacteria 2|Bacteria M NAD(P)H-binding - - 1.1.1.219 ko:K00091 - - - - ko00000,ko01000 - - - Epimerase SJTD3_k127_5313663_4 1220534.B655_1981 8.556e-37 154.0 arCOG10178@1|root,arCOG10178@2157|Archaea,2XY0I@28890|Euryarchaeota 28890|Euryarchaeota S CAAX protease self-immunity - - - - - - - - - - - - Abi SJTD3_k127_5313663_0 485913.Krac_10953 1.376e-221 702.0 COG0143@1|root,COG0143@2|Bacteria,2G5ZU@200795|Chloroflexi 200795|Chloroflexi J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g SJTD3_k127_5313663_5 530564.Psta_1154 1.167e-15 82.0 2BRK5@1|root,32KJB@2|Bacteria,2J42Y@203682|Planctomycetes 203682|Planctomycetes - - - - - - - - - - - - - - - SJTD3_k127_5313663_3 525904.Tter_0104 7.254e-83 289.0 COG1215@1|root,COG1215@2|Bacteria,2NPW4@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_5313663_2 219305.MCAG_00627 1.746e-86 321.0 COG1404@1|root,COG3055@1|root,COG1404@2|Bacteria,COG3055@2|Bacteria,2HU5X@201174|Actinobacteria,4DBT0@85008|Micromonosporales 201174|Actinobacteria O Peptidase S8 and S53 subtilisin kexin sedolisin - - - - - - - - - - - - CarboxypepD_reg,Cleaved_Adhesin,Kelch_1,Peptidase_S8 SJTD3_k127_5329909_0 1521187.JPIM01000020_gene232 4.316e-171 558.0 COG0683@1|root,COG0683@2|Bacteria,2G904@200795|Chloroflexi,3754R@32061|Chloroflexia 32061|Chloroflexia E Periplasmic binding protein domain - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 SJTD3_k127_5329909_2 1382356.JQMP01000004_gene653 1.815e-34 152.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_5329909_1 926550.CLDAP_25170 6.637e-132 426.0 COG0596@1|root,COG0596@2|Bacteria,2GA9B@200795|Chloroflexi 200795|Chloroflexi S Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_5352414_0 1382306.JNIM01000001_gene1327 1.065e-121 402.0 COG0064@1|root,COG0064@2|Bacteria,2G62Q@200795|Chloroflexi 200795|Chloroflexi J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB - 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey SJTD3_k127_5352414_1 264732.Moth_2249 1.309e-37 153.0 COG3879@1|root,COG3879@2|Bacteria,1V0FG@1239|Firmicutes,24DRC@186801|Clostridia,42G46@68295|Thermoanaerobacterales 186801|Clostridia S Bacterial protein of unknown function (DUF881) - - - - - - - - - - - - DUF881 SJTD3_k127_5352414_3 316274.Haur_2282 8.383e-24 109.0 COG3879@1|root,COG3879@2|Bacteria 2|Bacteria S Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - - - - - - - - - - DUF881 SJTD3_k127_5352414_2 105420.BBPO01000002_gene7363 2.893e-26 112.0 COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,2NMCI@228398|Streptacidiphilus 201174|Actinobacteria K Bacterial regulatory helix-turn-helix proteins, AraC family - - - - - - - - - - - - HTH_18 SJTD3_k127_5352998_1 926560.KE387023_gene2500 1.93e-187 595.0 COG3055@1|root,COG3055@2|Bacteria 2|Bacteria G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - - - - - - - - - - Kelch_1,Malectin,TIG SJTD3_k127_5352998_0 479431.Namu_4792 3.221e-196 629.0 COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4ETRQ@85013|Frankiales 201174|Actinobacteria EGP PFAM major facilitator superfamily MFS_1 - - - ko:K08167 - M00713,M00714 - - ko00000,ko00002,ko01504,ko02000 2.A.1.3 - - MFS_1 SJTD3_k127_5352998_2 479434.Sthe_1273 5.226e-176 563.0 COG0277@1|root,COG0277@2|Bacteria 2|Bacteria C FAD linked oxidase domain protein - - - - - - - - - - - - BBE,FAD_binding_4 SJTD3_k127_5352998_4 37919.EP51_14000 5.857e-24 104.0 COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4G39U@85025|Nocardiaceae 201174|Actinobacteria K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - AHSA1,HTH_20 SJTD3_k127_5352998_3 1500301.JQMF01000002_gene706 9.595e-48 179.0 COG3832@1|root,COG3832@2|Bacteria,1RJ7U@1224|Proteobacteria,2U9W0@28211|Alphaproteobacteria,4BE9Z@82115|Rhizobiaceae 28211|Alphaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 SJTD3_k127_5360979_14 2002.JOEQ01000095_gene6653 2.069e-05 51.0 COG1020@1|root,COG1020@2|Bacteria,2GISR@201174|Actinobacteria 201174|Actinobacteria Q Non-ribosomal peptide synthetase modules and related proteins - - - - - - - - - - - - AMP-binding,AMP-binding_C,Condensation,PP-binding,Thioesterase SJTD3_k127_5360979_3 479434.Sthe_0020 5.002e-124 413.0 28MN1@1|root,2ZAXN@2|Bacteria,2G6CU@200795|Chloroflexi,27XP5@189775|Thermomicrobia 189775|Thermomicrobia S Terminase-like family - - - - - - - - - - - - Terminase_6C SJTD3_k127_5360979_6 525904.Tter_1769 2.478e-96 336.0 COG3567@1|root,COG3567@2|Bacteria 2|Bacteria F Phage-associated protein, HI1409 family - - - - - - - - - - - - DUF1073,Phage_prot_Gp6 SJTD3_k127_5360979_5 1382356.JQMP01000003_gene1403 2.202e-103 344.0 2DBIJ@1|root,2Z9G2@2|Bacteria,2G896@200795|Chloroflexi,27XN4@189775|Thermomicrobia 189775|Thermomicrobia S Phage capsid family - - - - - - - - - - - - Phage_capsid SJTD3_k127_5360979_13 1156844.KB891798_gene6299 5.631e-06 55.0 COG3023@1|root,COG3023@2|Bacteria,2GJ9M@201174|Actinobacteria 201174|Actinobacteria V Negative regulator of - - - - - - - - - - - - Amidase_2 SJTD3_k127_5360979_1 749927.AMED_7297 2.72e-144 516.0 COG3209@1|root,COG5184@1|root,COG3209@2|Bacteria,COG5184@2|Bacteria,2GMBB@201174|Actinobacteria,4E3ST@85010|Pseudonocardiales 201174|Actinobacteria M RHS Repeat - - - - - - - - - - - - RHS_repeat,TIG SJTD3_k127_5360979_2 247490.KSU1_C0714 1.406e-131 475.0 COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes 203682|Planctomycetes O alpha-L-arabinofuranosidase - - - - - - - - - - - - SBBP SJTD3_k127_5360979_10 1382356.JQMP01000003_gene1664 1.467e-29 124.0 COG5309@1|root,COG5309@2|Bacteria,2G8VX@200795|Chloroflexi,27XUZ@189775|Thermomicrobia 189775|Thermomicrobia G Glycosyl hydrolase catalytic core - - - - - - - - - - - - Glyco_hydro_cc SJTD3_k127_5360979_9 1089548.KI783301_gene2029 8.057e-45 174.0 COG1525@1|root,COG3858@1|root,COG1525@2|Bacteria,COG3858@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,3WETJ@539002|Bacillales incertae sedis 91061|Bacilli L Staphylococcal nuclease homologues nucH - 3.1.31.1 ko:K01174 - - - - ko00000,ko01000 - - - SNase SJTD3_k127_5360979_12 1128421.JAGA01000003_gene3656 1.105e-15 79.0 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - RHS_repeat SJTD3_k127_5360979_8 1128421.JAGA01000003_gene3655 5.453e-52 200.0 COG3209@1|root,COG3209@2|Bacteria 2|Bacteria M self proteolysis - - - - - - - - - - - - RHS_repeat SJTD3_k127_5360979_11 357808.RoseRS_2323 1.719e-17 95.0 COG3209@1|root,COG3209@2|Bacteria,2G6KZ@200795|Chloroflexi,376AQ@32061|Chloroflexia 32061|Chloroflexia M Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - RHS_repeat SJTD3_k127_5360979_4 243164.DET1472 9.804e-108 398.0 COG3209@1|root,COG3391@1|root,COG3209@2|Bacteria,COG3391@2|Bacteria,2G9X3@200795|Chloroflexi,34DP2@301297|Dehalococcoidia 301297|Dehalococcoidia M amine dehydrogenase activity - - - - - - - - - - - - - SJTD3_k127_5360979_0 247490.KSU1_C0714 6.873e-150 532.0 COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes 203682|Planctomycetes O alpha-L-arabinofuranosidase - - - - - - - - - - - - SBBP SJTD3_k127_5360979_7 285514.JNWO01000002_gene5391 4.16e-88 332.0 COG3170@1|root,COG3209@1|root,COG3170@2|Bacteria,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria 201174|Actinobacteria M COG3209 Rhs family protein - - - - - - - - - - - - RHS_repeat SJTD3_k127_5371219_6 765420.OSCT_2759 1.443e-27 115.0 COG1430@1|root,COG1430@2|Bacteria,2GAEN@200795|Chloroflexi,375TZ@32061|Chloroflexia 32061|Chloroflexia S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 SJTD3_k127_5371219_3 479434.Sthe_0521 6.368e-92 312.0 COG2064@1|root,COG2064@2|Bacteria,2G6CF@200795|Chloroflexi,27XSY@189775|Thermomicrobia 189775|Thermomicrobia NU Type II secretion system (T2SS), protein F - - - ko:K12511 - - - - ko00000,ko02044 - - - T2SSF SJTD3_k127_5371219_4 383372.Rcas_1681 8.619e-92 312.0 COG4965@1|root,COG4965@2|Bacteria,2G6GS@200795|Chloroflexi,3755T@32061|Chloroflexia 32061|Chloroflexia U PFAM type II secretion system protein - - - ko:K12510 - - - - ko00000,ko02044 - - - T2SSF SJTD3_k127_5371219_0 479434.Sthe_0519 3.817e-216 680.0 COG4962@1|root,COG4962@2|Bacteria,2G68E@200795|Chloroflexi,27XTR@189775|Thermomicrobia 189775|Thermomicrobia U Type II/IV secretion system protein - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE SJTD3_k127_5371219_1 357808.RoseRS_1273 2.868e-129 426.0 COG4753@1|root,COG4963@1|root,COG4753@2|Bacteria,COG4963@2|Bacteria,2G6CH@200795|Chloroflexi,37524@32061|Chloroflexia 32061|Chloroflexia D PFAM response regulator receiver - - - ko:K02282 - - - - ko00000,ko02035,ko02044 - - - AAA_31,ParA,Response_reg SJTD3_k127_5371219_9 479434.Sthe_0517 7.57e-16 89.0 COG3745@1|root,COG3745@2|Bacteria,2G7H3@200795|Chloroflexi,27XF4@189775|Thermomicrobia 189775|Thermomicrobia U SAF - - - ko:K02279 - - - - ko00000,ko02035,ko02044 - - - RcpC,SAF SJTD3_k127_5371219_5 765420.OSCT_2913 4.297e-68 244.0 COG1216@1|root,COG1216@2|Bacteria,2G7S5@200795|Chloroflexi,374RY@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_5371219_2 926569.ANT_19690 5.551e-117 394.0 COG0624@1|root,COG0624@2|Bacteria,2G5IT@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M20 - - - - - - - - - - - - M20_dimer,Peptidase_M20 SJTD3_k127_5371219_8 316274.Haur_4691 1.186e-16 91.0 COG0631@1|root,COG3204@1|root,COG0631@2|Bacteria,COG3204@2|Bacteria,2G72P@200795|Chloroflexi,374Z2@32061|Chloroflexia 32061|Chloroflexia T protein serine/threonine phosphatase activity - - - - - - - - - - - - - SJTD3_k127_5381796_4 370438.PTH_0851 5.639e-64 235.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,261MT@186807|Peptococcaceae 186801|Clostridia C Iron-containing alcohol dehydrogenase - - - ko:K19954 - - - - ko00000,ko01000 - - - Fe-ADH SJTD3_k127_5381796_6 1347086.CCBA010000023_gene2099 4.844e-40 162.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4HCSN@91061|Bacilli,1ZD3D@1386|Bacillus 91061|Bacilli G COG1879 ABC-type sugar transport system, periplasmic component rbsB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10439 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_5381796_3 1229520.ADIAL_1931 1.688e-66 239.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,27FZZ@186828|Carnobacteriaceae 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_5381796_5 1134413.ANNK01000134_gene3090 4.979e-47 184.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,1ZBAZ@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_5381796_0 1382306.JNIM01000001_gene23 4.789e-163 528.0 COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi 200795|Chloroflexi P Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system rbsA - 3.6.3.17 ko:K10562 ko02010,map02010 M00220 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.9 - - ABC_tran SJTD3_k127_5381796_2 1122915.AUGY01000010_gene4620 1.422e-76 269.0 COG1609@1|root,COG1609@2|Bacteria,1TRZW@1239|Firmicutes,4HD7B@91061|Bacilli,274HM@186822|Paenibacillaceae 91061|Bacilli K helix_turn _helix lactose operon repressor - - - ko:K02529,ko:K03435 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 SJTD3_k127_5381796_1 247490.KSU1_C0714 4.496e-131 460.0 COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes 203682|Planctomycetes O alpha-L-arabinofuranosidase - - - - - - - - - - - - SBBP SJTD3_k127_5381796_7 864702.OsccyDRAFT_3831 4.754e-08 67.0 COG5267@1|root,COG5267@2|Bacteria,1G55R@1117|Cyanobacteria,1HBT0@1150|Oscillatoriales 1117|Cyanobacteria S PFAM S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_5382578_1 867903.ThesuDRAFT_01312 1.977e-145 469.0 COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,3WCXQ@538999|Clostridiales incertae sedis 186801|Clostridia IQ Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - 6.2.1.3 ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C SJTD3_k127_5382578_0 292459.STH3012 7.942e-264 834.0 COG1024@1|root,COG1250@1|root,COG1024@2|Bacteria,COG1250@2|Bacteria,1TR8J@1239|Firmicutes,247RR@186801|Clostridia 186801|Clostridia I 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - 1.1.1.35 ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 M00087 R01975,R04737,R04739,R04741,R04743,R04745,R04748,R05305 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000 - - - 3HCDH,3HCDH_N,ECH_1 SJTD3_k127_5382578_2 1499680.CCFE01000011_gene425 1.675e-141 459.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,4H9RJ@91061|Bacilli,1ZBKX@1386|Bacillus 91061|Bacilli I Belongs to the thiolase family fadA - 2.3.1.16 ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 M00087,M00113 R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095 RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955 ko00000,ko00001,ko00002,ko01000 - - - Thiolase_C,Thiolase_N SJTD3_k127_5382578_3 1125863.JAFN01000001_gene841 5.04e-80 276.0 COG0318@1|root,COG0318@2|Bacteria,1MUMC@1224|Proteobacteria,42NT5@68525|delta/epsilon subdivisions,2WIWR@28221|Deltaproteobacteria 28221|Deltaproteobacteria IQ PFAM AMP-dependent synthetase and ligase alkK - 6.2.1.3 ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 M00086 R01280 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 4.C.1.1 - - AMP-binding,AMP-binding_C SJTD3_k127_5384225_0 573370.DMR_08510 5.366e-06 59.0 COG5305@1|root,COG5305@2|Bacteria,1PZ3W@1224|Proteobacteria,436P4@68525|delta/epsilon subdivisions,2X1B3@28221|Deltaproteobacteria,2MEP2@213115|Desulfovibrionales 28221|Deltaproteobacteria S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_5384225_1 1125863.JAFN01000001_gene851 0.0004874 46.0 2EM0B@1|root,33EPU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5388261_0 525904.Tter_0754 3.362e-37 150.0 298YA@1|root,32VWC@2|Bacteria,2NRHS@2323|unclassified Bacteria 2|Bacteria S Protein of unknown function (DUF3090) - - - - - - - - - - - - DUF3090 SJTD3_k127_5397530_0 309799.DICTH_0782 6.107e-181 580.0 COG0017@1|root,COG0017@2|Bacteria 2|Bacteria J Asparaginyl-tRNA synthetase asnS GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon SJTD3_k127_5397530_2 511051.CSE_03850 7.831e-79 281.0 COG2182@1|root,COG2182@2|Bacteria 2|Bacteria G maltose binding - - - ko:K15770,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1,Cu_amine_oxidN1,SBP_bac_8 SJTD3_k127_5397530_1 511051.CSE_03860 8.652e-114 377.0 COG1175@1|root,COG1175@2|Bacteria 2|Bacteria P transmembrane transport malF - - ko:K02025,ko:K15770,ko:K15771 ko02010,map02010 M00207,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1,SBP_bac_8 SJTD3_k127_5397530_3 511051.CSE_03870 2.66e-30 127.0 COG3833@1|root,COG3833@2|Bacteria 2|Bacteria P maltose-transporting ATPase activity malG - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 SJTD3_k127_5410286_1 485913.Krac_0757 1.358e-39 151.0 2F4NJ@1|root,33XBV@2|Bacteria,2G8ND@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - SJTD3_k127_5410286_0 1121930.AQXG01000002_gene1952 1.047e-218 702.0 COG1042@1|root,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,1IVTU@117747|Sphingobacteriia 976|Bacteroidetes C CoA binding domain - - - ko:K09181 - - - - ko00000 - - - ATP-grasp_5,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig SJTD3_k127_5410286_2 1382356.JQMP01000003_gene1484 4.273e-19 87.0 COG0473@1|root,COG0473@2|Bacteria,2G8A7@200795|Chloroflexi,27XIB@189775|Thermomicrobia 189775|Thermomicrobia C Isocitrate/isopropylmalate dehydrogenase - - 1.1.1.83,1.1.1.93,4.1.1.73 ko:K07246 ko00630,ko00650,map00630,map00650 - R00215,R01751,R02545,R06180 RC00084,RC00105,RC00594 ko00000,ko00001,ko01000 - - - Iso_dh SJTD3_k127_5428155_2 749414.SBI_00138 2.541e-43 164.0 COG0477@1|root,COG0477@2|Bacteria,2I48M@201174|Actinobacteria 201174|Actinobacteria EGP Major facilitator superfamily - - - - - - - - - - - - MFS_1,MFS_3 SJTD3_k127_5428155_3 1125863.JAFN01000001_gene2065 1.576e-31 137.0 COG2199@1|root,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42M4Q@68525|delta/epsilon subdivisions,2X5DU@28221|Deltaproteobacteria 28221|Deltaproteobacteria T Diguanylate cyclase - - - - - - - - - - - iAF987.Gmet_0069 GGDEF,Response_reg SJTD3_k127_5428155_1 485913.Krac_2500 8.753e-79 278.0 COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi 200795|Chloroflexi M PFAM Glycosyl transferase family 2 - - - ko:K14597 ko00906,map00906 - R07544,R07546 RC00262 ko00000,ko00001 - - - Glycos_transf_2 SJTD3_k127_5428155_0 266117.Rxyl_2066 1.315e-141 474.0 COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4CQDA@84995|Rubrobacteria 84995|Rubrobacteria I Acyltransferase family - - - - - - - - - - - - Acyl_transf_3 SJTD3_k127_5431763_1 479434.Sthe_3410 5.923e-33 138.0 COG0500@1|root,COG2890@1|root,COG2226@2|Bacteria,COG2890@2|Bacteria,2G9F9@200795|Chloroflexi 200795|Chloroflexi Q Methyltransferase domain - - - - - - - - - - - - - SJTD3_k127_5431763_2 1121472.AQWN01000008_gene2019 4.7e-06 59.0 COG3307@1|root,COG3307@2|Bacteria,1TQGY@1239|Firmicutes,24AB7@186801|Clostridia,261YW@186807|Peptococcaceae 186801|Clostridia M PFAM O-Antigen - - - ko:K18814 - - - - ko00000,ko02000 9.B.67.1 - - Wzy_C SJTD3_k127_5431763_0 479434.Sthe_3403 1.906e-33 143.0 COG2244@1|root,COG2244@2|Bacteria 2|Bacteria S polysaccharide biosynthetic process - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_3,Polysacc_synt_C SJTD3_k127_5445437_0 1192034.CAP_7857 1.428e-113 379.0 COG1744@1|root,COG1744@2|Bacteria,1R7WA@1224|Proteobacteria,434SK@68525|delta/epsilon subdivisions,2WZ3N@28221|Deltaproteobacteria,2Z19A@29|Myxococcales 28221|Deltaproteobacteria S ABC transporter substrate-binding protein PnrA-like med - - ko:K07335 - - - - ko00000 - - - Bmp SJTD3_k127_5445437_1 1254432.SCE1572_44710 1.843e-106 361.0 COG4603@1|root,COG4603@2|Bacteria,1MX6V@1224|Proteobacteria,42Q6K@68525|delta/epsilon subdivisions,2WM2U@28221|Deltaproteobacteria,2YX9P@29|Myxococcales 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SJTD3_k127_5445437_2 448385.sce7756 5.001e-70 244.0 COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,42P6E@68525|delta/epsilon subdivisions,2WISH@28221|Deltaproteobacteria,2YV40@29|Myxococcales 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SJTD3_k127_5482548_1 1128421.JAGA01000002_gene1527 6.286e-15 87.0 COG1287@1|root,COG1287@2|Bacteria 2|Bacteria S oligosaccharyl transferase activity - - - - - - - - - - - - Glycos_transf_2,PMT_2 SJTD3_k127_5482548_0 357808.RoseRS_0854 1.499e-24 117.0 COG1287@1|root,COG1287@2|Bacteria,2GA8N@200795|Chloroflexi,374X5@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_5488603_0 251221.35214577 4.812e-30 121.0 COG0249@1|root,COG0249@2|Bacteria 2|Bacteria L mismatched DNA binding mutS1 - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_III,MutS_V SJTD3_k127_5488603_2 999611.KI421504_gene629 5.857e-10 72.0 COG3794@1|root,COG3794@2|Bacteria,1RI9G@1224|Proteobacteria,2U7KA@28211|Alphaproteobacteria 28211|Alphaproteobacteria C PFAM blue (type 1) copper domain protein - - - - - - - - - - - - Copper-bind,Cupredoxin_1 SJTD3_k127_5488603_1 1347368.HG964403_gene4308 4.947e-12 78.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli,1ZPUS@1386|Bacillus 91061|Bacilli M Cell wall hydrolase autolysin lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH SJTD3_k127_549502_1 926569.ANT_05420 5.377e-61 218.0 COG0524@1|root,COG0524@2|Bacteria,2G6JH@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway rbsK - 2.7.1.15 ko:K00852 ko00030,map00030 - R01051,R02750 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB SJTD3_k127_549502_2 1007103.AFHW01000025_gene315 9.185e-39 148.0 COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,4HIFW@91061|Bacilli,26YTI@186822|Paenibacillaceae 91061|Bacilli G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose rbsD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034219,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702 5.4.99.62 ko:K06726 ko02010,map02010 - R08247 RC02247 ko00000,ko00001,ko01000 - - - RbsD_FucU SJTD3_k127_549502_0 1089551.KE386572_gene1239 7.771e-117 386.0 COG5426@1|root,COG5426@2|Bacteria,1NPB8@1224|Proteobacteria,2U1M7@28211|Alphaproteobacteria 28211|Alphaproteobacteria S Putative glutamine amidotransferase - - - - - - - - - - - - GATase1_like SJTD3_k127_549502_3 429009.Adeg_0662 1.275e-20 92.0 COG0757@1|root,COG0757@2|Bacteria,1V6E8@1239|Firmicutes,24JBK@186801|Clostridia,42GJA@68295|Thermoanaerobacterales 186801|Clostridia E Catalyzes a trans-dehydration via an enolate intermediate aroQ - 4.2.1.10 ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_II SJTD3_k127_5498134_2 525904.Tter_2777 1.712e-31 142.0 COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria 2|Bacteria G Galactose oxidase, central domain - - - - - - - - - - - - Big_5,CBM_35,CBM_6,GSDH,Kelch_1,Kelch_6 SJTD3_k127_5498134_3 1160707.AJIK01000008_gene813 9.382e-16 91.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli,26CTR@186818|Planococcaceae 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH SJTD3_k127_5498134_0 926550.CLDAP_20840 0.0 1004.0 COG0441@1|root,COG0441@2|Bacteria,2G5PZ@200795|Chloroflexi 200795|Chloroflexi J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS - 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_SAD SJTD3_k127_5498134_1 309801.trd_1634 2.086e-132 434.0 COG1104@1|root,COG1104@2|Bacteria,2G63V@200795|Chloroflexi,27XYX@189775|Thermomicrobia 189775|Thermomicrobia E Beta-eliminating lyase - - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 SJTD3_k127_551409_0 1121346.KB899816_gene3255 3.431e-272 857.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,26QSY@186822|Paenibacillaceae 91061|Bacilli F Belongs to the CarB family carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS SJTD3_k127_551409_7 1296990.H845_2173 6.394e-90 309.0 COG0505@1|root,COG0505@2|Bacteria,1MUB9@1224|Proteobacteria,2TR3W@28211|Alphaproteobacteria,2JPGJ@204441|Rhodospirillales 204441|Rhodospirillales F Belongs to the CarA family carA - 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase SJTD3_k127_551409_10 1227360.C176_04818 0.0001297 53.0 COG0791@1|root,COG0791@2|Bacteria,1V9ZW@1239|Firmicutes,4HDB9@91061|Bacilli,26I8Y@186818|Planococcaceae 1239|Firmicutes M COG0791 Cell wall-associated hydrolases (invasion-associated proteins) ydhO1 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Cu_amine_oxidN1,LysM,NLPC_P60,SH3_3 SJTD3_k127_551409_8 1123368.AUIS01000023_gene896 2.359e-60 221.0 COG2267@1|root,COG2267@2|Bacteria,1QYVT@1224|Proteobacteria 1224|Proteobacteria I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_551409_3 373903.Hore_04900 7.766e-127 430.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WB7X@53433|Halanaerobiales 186801|Clostridia E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SJTD3_k127_551409_5 484019.THA_33 4.517e-106 355.0 COG0601@1|root,COG0601@2|Bacteria,2GBX3@200918|Thermotogae 200918|Thermotogae P PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 SJTD3_k127_551409_6 1150474.JQJI01000048_gene1240 1.214e-90 308.0 COG1173@1|root,COG1173@2|Bacteria,2GCHA@200918|Thermotogae 200918|Thermotogae EP PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1,OppC_N SJTD3_k127_551409_2 649638.Trad_0506 1.706e-160 528.0 COG1132@1|root,COG1132@2|Bacteria,1WISJ@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V ABC transporter transmembrane region - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SJTD3_k127_551409_1 649638.Trad_0505 4.872e-196 629.0 COG1132@1|root,COG1132@2|Bacteria,1WKZ0@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus V ABC transporter transmembrane region - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SJTD3_k127_551409_4 1192034.CAP_0522 8.704e-118 396.0 COG2124@1|root,COG2124@2|Bacteria,1MV75@1224|Proteobacteria,42VMP@68525|delta/epsilon subdivisions 1224|Proteobacteria C cytochrome P450 - - 1.11.2.4 ko:K15629 - - R09740 - ko00000,ko00199,ko01000 - - - p450 SJTD3_k127_5514130_0 272558.10176423 5.118e-136 443.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAKV@91061|Bacilli,1ZPZN@1386|Bacillus 91061|Bacilli I acyl-CoA dehydrogenase acdA - 1.3.8.1,1.3.8.7 ko:K00248,ko:K00249 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 M00013,M00036,M00087 R00924,R01175,R01178,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754 RC00052,RC00068,RC00076,RC00095,RC00120,RC00148,RC00246 ko00000,ko00001,ko00002,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SJTD3_k127_5514130_1 1125863.JAFN01000001_gene3236 8.449e-118 385.0 COG1250@1|root,COG1250@2|Bacteria,1MU9P@1224|Proteobacteria,42M6J@68525|delta/epsilon subdivisions,2WJZQ@28221|Deltaproteobacteria 28221|Deltaproteobacteria I PFAM 3-hydroxyacyl-CoA dehydrogenase - - 1.1.1.157 ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 - R01976,R05576,R06941 RC00029,RC00117 ko00000,ko00001,ko01000 - - - 3HCDH,3HCDH_N SJTD3_k127_5514130_2 1382306.JNIM01000001_gene2518 7.17e-116 389.0 COG0205@1|root,COG0205@2|Bacteria,2G81H@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions pfp - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK SJTD3_k127_5514130_4 1132442.KB889752_gene3016 3.069e-18 100.0 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZBKV@1386|Bacillus 91061|Bacilli L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Excalibur,HHH_3,LTD,Lactamase_B,SLH SJTD3_k127_5514130_3 479434.Sthe_1693 9.862e-50 202.0 COG3693@1|root,COG5479@1|root,COG3693@2|Bacteria,COG5479@2|Bacteria,2GBGU@200795|Chloroflexi,27Y52@189775|Thermomicrobia 200795|Chloroflexi M Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase SJTD3_k127_5520329_2 292459.STH1400 6.098e-23 102.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia 186801|Clostridia HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 SJTD3_k127_5520329_3 398767.Glov_1317 1.626e-21 99.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1MWCC@1224|Proteobacteria,42P6I@68525|delta/epsilon subdivisions,2WMAF@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 SJTD3_k127_5520329_0 316274.Haur_1815 5.81e-195 641.0 COG1716@1|root,COG1716@2|Bacteria,2G8A1@200795|Chloroflexi,377ZW@32061|Chloroflexia 32061|Chloroflexia T Clostripain family - - - - - - - - - - - - Peptidase_C11 SJTD3_k127_5520329_1 485913.Krac_4260 6.947e-31 125.0 2DQ8Q@1|root,335AV@2|Bacteria,2G9D1@200795|Chloroflexi 200795|Chloroflexi S pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - - - - - - - - - - F420H2_quin_red SJTD3_k127_5521216_12 309803.CTN_0366 6.103e-44 172.0 COG1129@1|root,COG1129@2|Bacteria 2|Bacteria G ABC transporter rbsA - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_5521216_9 926550.CLDAP_32860 8.764e-78 268.0 COG1028@1|root,COG1028@2|Bacteria,2G6IK@200795|Chloroflexi 200795|Chloroflexi IQ PFAM short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 SJTD3_k127_5521216_1 926550.CLDAP_32850 4.561e-155 502.0 COG1879@1|root,COG1879@2|Bacteria 2|Bacteria G ABC-type sugar transport system periplasmic component - - - ko:K02058,ko:K10439 ko02010,ko02030,map02010,map02030 M00212,M00221 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - Peripla_BP_4 SJTD3_k127_5521216_3 926550.CLDAP_40620 2.941e-118 389.0 COG0169@1|root,COG0169@2|Bacteria,2G8BG@200795|Chloroflexi 200795|Chloroflexi E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - - - - - - - - - - - SJTD3_k127_5521216_7 926550.CLDAP_40630 8.306e-83 286.0 COG0800@1|root,COG0800@2|Bacteria,2G8MI@200795|Chloroflexi 200795|Chloroflexi G KDPG and KHG aldolase - - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase SJTD3_k127_5521216_2 926550.CLDAP_40640 3.914e-128 417.0 COG0111@1|root,COG0111@2|Bacteria,2G7NG@200795|Chloroflexi 200795|Chloroflexi EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C SJTD3_k127_5521216_8 926550.CLDAP_40650 1.939e-78 266.0 COG2140@1|root,COG2140@2|Bacteria,2G9AT@200795|Chloroflexi 200795|Chloroflexi G Glucose-6-phosphate isomerase (GPI) - - 5.3.1.9 ko:K06859 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000 - - - GPI SJTD3_k127_5521216_5 1304865.JAGF01000001_gene2276 4.189e-97 328.0 COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria 201174|Actinobacteria E alcohol dehydrogenase tdh - - - - - - - - - - - ADH_N,ADH_zinc_N SJTD3_k127_5521216_4 1304865.JAGF01000001_gene2275 1.122e-97 330.0 COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4F2YX@85016|Cellulomonadaceae 201174|Actinobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C SJTD3_k127_5521216_0 926550.CLDAP_32900 7.951e-169 544.0 COG1070@1|root,COG1070@2|Bacteria 2|Bacteria G xylulokinase activity - - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 ko:K00848,ko:K00851,ko:K00854,ko:K00862 ko00030,ko00040,ko00051,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00040,map00051,map01100,map01110,map01120,map01130,map01200 M00014 R01639,R01737,R01902,R03014,R11536 RC00002,RC00017,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N SJTD3_k127_5521216_6 158190.SpiGrapes_2373 1.124e-89 305.0 COG1082@1|root,COG1082@2|Bacteria,2J8EP@203691|Spirochaetes 203691|Spirochaetes G TIM barrel - - 5.1.3.30,5.1.3.31 ko:K18910 - - R10817,R10818 RC03111,RC03283 ko00000,ko01000 - - - AP_endonuc_2 SJTD3_k127_5521216_11 1128421.JAGA01000003_gene3268 7.782e-65 227.0 COG1428@1|root,COG1428@2|Bacteria,2NPEH@2323|unclassified Bacteria 2|Bacteria F Deoxynucleoside kinase dgk - 2.7.1.113 ko:K15518 ko00230,map00230 - R01967 RC00002,RC00017 ko00000,ko00001,ko01000 - - - HPPK,dNK SJTD3_k127_5521216_14 40571.JOEA01000005_gene4335 8.395e-20 101.0 2A6H6@1|root,30VAG@2|Bacteria,2H9KC@201174|Actinobacteria,4ECBZ@85010|Pseudonocardiales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_5521216_10 1242864.D187_003615 5.615e-69 239.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_C_6,TetR_N SJTD3_k127_5521216_13 47763.JNZA01000027_gene5892 1.095e-34 136.0 COG0654@1|root,COG0654@2|Bacteria,2GJ9V@201174|Actinobacteria 201174|Actinobacteria CH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - - - - - - - - - - FAD_binding_3 SJTD3_k127_552968_2 298655.KI912266_gene1681 3.485e-32 129.0 COG2730@1|root,COG2730@2|Bacteria,2HW9X@201174|Actinobacteria 201174|Actinobacteria G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - 3.2.1.4 ko:K01179 ko00500,ko01100,map00500,map01100 - R06200,R11307,R11308 - ko00000,ko00001,ko01000 - GH5,GH9 - CBM_2,Cellulase SJTD3_k127_552968_1 1521187.JPIM01000005_gene2273 2.834e-85 297.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups epsO - - - - - - - - - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2 SJTD3_k127_552968_0 1380390.JIAT01000014_gene6183 6.565e-104 355.0 COG0438@1|root,COG0438@2|Bacteria,2IN8Y@201174|Actinobacteria 201174|Actinobacteria M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4 SJTD3_k127_552968_3 338969.Rfer_0659 3.291e-06 59.0 COG3206@1|root,COG3206@2|Bacteria,1MVBX@1224|Proteobacteria,2VMDA@28216|Betaproteobacteria,4ADEV@80864|Comamonadaceae 28216|Betaproteobacteria M G-rich domain on putative tyrosine kinase - - - - - - - - - - - - GNVR,Wzz SJTD3_k127_5538527_2 926569.ANT_12690 3.185e-69 246.0 COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi 200795|Chloroflexi P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import - - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM,PDGLE SJTD3_k127_5538527_3 1382306.JNIM01000001_gene2643 1.559e-54 201.0 COG1321@1|root,COG1321@2|Bacteria,2G7DY@200795|Chloroflexi 200795|Chloroflexi K iron dependent repressor - - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA SJTD3_k127_5538527_4 706587.Desti_2735 2.309e-21 99.0 COG1729@1|root,COG4232@1|root,COG1729@2|Bacteria,COG4232@2|Bacteria,1N0AW@1224|Proteobacteria,42TGH@68525|delta/epsilon subdivisions,2WQ33@28221|Deltaproteobacteria,2MRZ1@213462|Syntrophobacterales 28221|Deltaproteobacteria CO Tetratricopeptide repeat - - - - - - - - - - - - TPR_6,Thioredoxin_2,Thioredoxin_7 SJTD3_k127_5538527_1 197221.22296173 1.02e-69 239.0 COG2343@1|root,COG2343@2|Bacteria,1G50P@1117|Cyanobacteria 1117|Cyanobacteria S protein conserved in bacteria - - - - - - - - - - - - NTP_transf_9 SJTD3_k127_5538527_0 357808.RoseRS_0137 3.703e-109 362.0 COG1232@1|root,COG1232@2|Bacteria,2G7T7@200795|Chloroflexi,3764F@32061|Chloroflexia 32061|Chloroflexia H PFAM amine oxidase - - - - - - - - - - - - Amino_oxidase SJTD3_k127_5546183_4 398767.Glov_0655 1.714e-87 295.0 COG0861@1|root,COG0861@2|Bacteria,1MWC9@1224|Proteobacteria,42MZB@68525|delta/epsilon subdivisions,2WKV4@28221|Deltaproteobacteria 28221|Deltaproteobacteria P PFAM Integral membrane protein TerC - - - - - - - - - - - - TerC SJTD3_k127_5546183_3 243233.MCA0142 8.916e-104 350.0 COG0387@1|root,COG0387@2|Bacteria,1N1MR@1224|Proteobacteria,1S1GI@1236|Gammaproteobacteria 1236|Gammaproteobacteria P Sodium/calcium exchanger protein - - - ko:K07300 - - - - ko00000,ko02000 2.A.19 - - Na_Ca_ex SJTD3_k127_5546183_6 525904.Tter_1980 1.944e-51 185.0 COG1917@1|root,COG1917@2|Bacteria,2NRVW@2323|unclassified Bacteria 2|Bacteria S Cupin domain - - - - - - - - - - - - Cupin_2 SJTD3_k127_5546183_1 525904.Tter_1977 1.995e-156 497.0 COG2141@1|root,COG2141@2|Bacteria,2NQXW@2323|unclassified Bacteria 2|Bacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_5546183_0 1444711.CCJF01000005_gene373 6.053e-169 535.0 COG0667@1|root,COG0667@2|Bacteria,2JGWJ@204428|Chlamydiae 204428|Chlamydiae C Aldo/keto reductase family - - - - - - - - - - - - Aldo_ket_red SJTD3_k127_5546183_2 1172185.KB911517_gene1822 2.472e-120 391.0 COG0599@1|root,COG0599@2|Bacteria,2GITB@201174|Actinobacteria,4FZNQ@85025|Nocardiaceae 201174|Actinobacteria S Carboxymuconolactone decarboxylase family - - 4.1.1.44 ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 - R03470 RC00938 ko00000,ko00001,ko01000 - - - CMD SJTD3_k127_5546183_5 590998.Celf_2289 4.289e-57 203.0 COG4334@1|root,COG4334@2|Bacteria,2IR4U@201174|Actinobacteria 201174|Actinobacteria S Uncharacterized protein conserved in bacteria (DUF2255) - - - - - - - - - - - - DUF2255 SJTD3_k127_5546183_7 485913.Krac_9101 7.454e-30 125.0 COG0789@1|root,COG0789@2|Bacteria 2|Bacteria K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - - - - - - - - - - MerR_1 SJTD3_k127_5561146_0 1128421.JAGA01000002_gene1822 3.082e-61 219.0 COG0472@1|root,COG0472@2|Bacteria,2NPJ8@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 4 rfe GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 SJTD3_k127_5561146_2 512565.AMIS_31080 6.439e-43 163.0 2BPUP@1|root,32IN9@2|Bacteria,2H785@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_5561146_1 383372.Rcas_2136 3.958e-43 167.0 COG1385@1|root,COG1385@2|Bacteria,2G70G@200795|Chloroflexi,3779B@32061|Chloroflexia 32061|Chloroflexia J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA SJTD3_k127_5585123_3 710687.KI912270_gene4284 0.0004571 53.0 COG3934@1|root,COG3934@2|Bacteria,2GK2J@201174|Actinobacteria,234Y5@1762|Mycobacteriaceae 201174|Actinobacteria G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase SJTD3_k127_5585123_2 926569.ANT_03770 6.686e-14 84.0 COG1719@1|root,COG1719@2|Bacteria,2G8D0@200795|Chloroflexi 200795|Chloroflexi S 4-vinyl reductase, 4VR - - - - - - - - - - - - V4R SJTD3_k127_5585123_0 383372.Rcas_0235 9.189e-17 93.0 COG3063@1|root,COG3063@2|Bacteria,2GBKI@200795|Chloroflexi,3781J@32061|Chloroflexia 32061|Chloroflexia NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - - SJTD3_k127_5585123_1 485913.Krac_4536 1.92e-15 82.0 COG0596@1|root,COG0596@2|Bacteria,2G6VQ@200795|Chloroflexi 2|Bacteria S PFAM alpha beta hydrolase fold MA20_20400 - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1,Abhydrolase_6 SJTD3_k127_5590222_1 1128421.JAGA01000004_gene2545 1.99e-64 236.0 COG0791@1|root,COG3807@1|root,COG0791@2|Bacteria,COG3807@2|Bacteria,2NRG9@2323|unclassified Bacteria 2|Bacteria M NlpC/P60 family yrvJ - 3.2.1.96,3.4.17.14,3.5.1.28,6.1.1.12 ko:K01227,ko:K01447,ko:K01448,ko:K01876,ko:K06385,ko:K07260,ko:K11060,ko:K11062,ko:K21471,ko:K21472 ko00511,ko00550,ko00970,ko01100,ko01502,ko01503,ko02020,map00511,map00550,map00970,map01100,map01502,map01503,map02020 M00359,M00360,M00651,M00727 R04112,R05577 RC00055,RC00064,RC00141,RC00523 ko00000,ko00001,ko00002,ko01000,ko01002,ko01007,ko01011,ko01504,ko02042,ko03016,ko03029,ko03036 - - - Amidase_3,NLPC_P60,SH3_3,SH3_4 SJTD3_k127_5590222_2 1120950.KB892820_gene723 1.686e-15 88.0 COG3173@1|root,COG3173@2|Bacteria,2GX3M@201174|Actinobacteria,4DV6D@85009|Propionibacteriales 201174|Actinobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH SJTD3_k127_5590222_0 324057.Pjdr2_2053 1.508e-70 241.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli,26QYB@186822|Paenibacillaceae 91061|Bacilli V ABC transporter yfiC - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SJTD3_k127_5628225_0 1304885.AUEY01000013_gene3127 1.1e-174 560.0 COG1914@1|root,COG1914@2|Bacteria,1MW6X@1224|Proteobacteria,42PNI@68525|delta/epsilon subdivisions,2WJNF@28221|Deltaproteobacteria,2MQ1R@213118|Desulfobacterales 28221|Deltaproteobacteria P Natural resistance-associated macrophage protein mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp,Usp SJTD3_k127_5628225_1 479434.Sthe_3064 3.558e-62 228.0 COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,27YAE@189775|Thermomicrobia 189775|Thermomicrobia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp SJTD3_k127_5628225_2 1128421.JAGA01000003_gene2709 1.917e-53 212.0 COG0589@1|root,COG1215@1|root,COG0589@2|Bacteria,COG1215@2|Bacteria,2NNSB@2323|unclassified Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups gpgS - 2.4.1.266,2.4.1.268 ko:K09118,ko:K13693,ko:K21349 - - - - ko00000,ko01000,ko01003 - GT81 - Glycos_transf_2,Usp SJTD3_k127_565546_1 1123393.KB891329_gene1015 6.593e-61 210.0 COG0221@1|root,COG0221@2|Bacteria,1RA2F@1224|Proteobacteria,2VQC0@28216|Betaproteobacteria,1KRJ7@119069|Hydrogenophilales 119069|Hydrogenophilales C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions ppa - 3.6.1.1 ko:K01507 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyrophosphatase SJTD3_k127_565546_0 292415.Tbd_1651 1.819e-114 369.0 COG0622@1|root,COG0622@2|Bacteria,1RCUQ@1224|Proteobacteria,2VTR8@28216|Betaproteobacteria 28216|Betaproteobacteria S Calcineurin-like phosphoesterase superfamily domain - - - ko:K07095 - - - - ko00000 - - - Metallophos_2 SJTD3_k127_565546_2 1177154.Y5S_01715 2.91e-09 61.0 2B4XH@1|root,32REP@2|Bacteria,1RJ9F@1224|Proteobacteria,1T0SV@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_5658815_0 479434.Sthe_0597 7.221e-125 419.0 COG2905@1|root,COG4191@1|root,COG2905@2|Bacteria,COG4191@2|Bacteria,2G807@200795|Chloroflexi 200795|Chloroflexi H SMART ATP-binding region ATPase domain protein - - - - - - - - - - - - HATPase_c,cNMP_binding SJTD3_k127_5658815_1 1122622.ATWJ01000011_gene2340 5.904e-34 149.0 COG5207@1|root,COG5207@2|Bacteria 2|Bacteria O Pfam Zn-finger in ubiquitin-hydrolases and other protein - - - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_N,zf-UBP SJTD3_k127_5658815_2 211165.AJLN01000016_gene2180 9.016e-28 113.0 COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1JK99@1189|Stigonemataceae 1117|Cyanobacteria KOT Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2,Response_reg SJTD3_k127_5676823_0 1128421.JAGA01000003_gene3696 1.625e-205 657.0 COG1164@1|root,COG1164@2|Bacteria,2NNVV@2323|unclassified Bacteria 2|Bacteria E Oligopeptidase F - - - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N SJTD3_k127_5676823_1 671143.DAMO_1984 3.24e-08 57.0 2CTJW@1|root,32STM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5685802_1 485913.Krac_10317 2.795e-109 360.0 COG2141@1|root,COG2141@2|Bacteria,2G873@200795|Chloroflexi 200795|Chloroflexi C COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_5685802_7 381666.H16_B1518 2.959e-22 100.0 COG2146@1|root,COG2146@2|Bacteria,1N8PE@1224|Proteobacteria,2VUAP@28216|Betaproteobacteria,1K8TQ@119060|Burkholderiaceae 28216|Betaproteobacteria P Rieske-like [2Fe-2S] domain - - - ko:K05710,ko:K18087 ko00360,ko00621,ko01100,ko01120,ko01220,map00360,map00621,map01100,map01120,map01220 M00543,M00545 R05261,R05262,R05263,R05264,R06782,R06783 RC00098 br01602,ko00000,ko00001,ko00002 - - - Rieske,Rieske_2 SJTD3_k127_5685802_3 1128421.JAGA01000001_gene2029 6.89e-95 324.0 COG0665@1|root,COG0665@2|Bacteria,2NRT0@2323|unclassified Bacteria 2|Bacteria E FAD dependent oxidoreductase puuB - - ko:K09471 ko00330,ko01100,map00330,map01100 M00136 R07415 RC00062 ko00000,ko00001,ko00002,ko01000 - - - DAO SJTD3_k127_5685802_5 1173020.Cha6605_1196 4.816e-73 251.0 COG0783@1|root,COG0783@2|Bacteria,1G54E@1117|Cyanobacteria 1117|Cyanobacteria P Belongs to the Dps family - - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin SJTD3_k127_5685802_6 525904.Tter_0456 4.423e-67 233.0 COG5405@1|root,COG5405@2|Bacteria,2NP72@2323|unclassified Bacteria 2|Bacteria O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery hslV GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 ko:K01419 - - - - ko00000,ko01000,ko01002 - - - Proteasome SJTD3_k127_5685802_0 479434.Sthe_0312 1.171e-148 486.0 COG1220@1|root,COG1220@2|Bacteria,2GBH6@200795|Chloroflexi,27XKZ@189775|Thermomicrobia 189775|Thermomicrobia O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis - - - ko:K03667 - - - - ko00000,ko03110 - - - AAA_2,ClpB_D2-small SJTD3_k127_5685802_4 324602.Caur_2685 4.585e-73 258.0 COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,2G6R8@200795|Chloroflexi,375F0@32061|Chloroflexia 32061|Chloroflexia K PFAM regulatory protein, MerR - - - ko:K22491 - - - - ko00000,ko03000 - - - B12-binding,B12-binding_2,MerR_1 SJTD3_k127_5685802_8 1121943.KB899990_gene3796 2.319e-13 80.0 COG4447@1|root,COG4447@2|Bacteria,1R6KJ@1224|Proteobacteria 1224|Proteobacteria S cellulose binding - - - - - - - - - - - - Sortilin-Vps10 SJTD3_k127_5685802_2 383372.Rcas_2276 1.04e-98 329.0 COG1252@1|root,COG1252@2|Bacteria,2G5SS@200795|Chloroflexi,376UK@32061|Chloroflexia 32061|Chloroflexia C PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - 1.6.99.3 ko:K03885 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - Pyr_redox_2 SJTD3_k127_5710246_0 35754.JNYJ01000019_gene80 1.597e-55 205.0 COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales 201174|Actinobacteria KT Transcriptional regulator - - - - - - - - - - - - AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12 SJTD3_k127_5711889_4 383372.Rcas_3039 1.292e-30 138.0 COG1874@1|root,COG1874@2|Bacteria,2GBMG@200795|Chloroflexi,376H5@32061|Chloroflexia 32061|Chloroflexia G Flagellar filament outer layer protein Flaa - - - - - - - - - - - - Glyco_hydro_42,Glyco_hydro_cc SJTD3_k127_5711889_5 350688.Clos_0923 7.704e-25 120.0 COG2367@1|root,COG2367@2|Bacteria,1UYZ3@1239|Firmicutes,24B7W@186801|Clostridia,36ESR@31979|Clostridiaceae 186801|Clostridia V Beta-lactamase enzyme family - - 3.5.2.6 ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 M00627,M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000,ko01504 - - - Beta-lactamase2 SJTD3_k127_5711889_2 1128421.JAGA01000004_gene2645 4.774e-44 181.0 COG1216@1|root,COG1216@2|Bacteria,2NRAF@2323|unclassified Bacteria 2|Bacteria S Glycosyl transferase, family 2 wgeF - - - - - - - - - - - GT87,Glycos_transf_2 SJTD3_k127_5711889_7 483219.LILAB_21070 5.842e-05 50.0 COG0008@1|root,COG0008@2|Bacteria,1MUCR@1224|Proteobacteria,42MAI@68525|delta/epsilon subdivisions,2WJ8M@28221|Deltaproteobacteria,2YV5P@29|Myxococcales 28221|Deltaproteobacteria J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX - 6.1.1.17 ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 M00121,M00359,M00360 R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 - - - tRNA-synt_1c SJTD3_k127_5711889_3 429009.Adeg_0626 6.644e-36 143.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,42F5V@68295|Thermoanaerobacterales 186801|Clostridia S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth SJTD3_k127_5711889_0 309801.trd_1505 4.306e-112 376.0 COG0612@1|root,COG0612@2|Bacteria,2G672@200795|Chloroflexi,27XSH@189775|Thermomicrobia 189775|Thermomicrobia S Belongs to the peptidase M16 family - - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C SJTD3_k127_5711889_1 869210.Marky_0477 1.573e-84 289.0 COG1001@1|root,COG1001@2|Bacteria,1WJ41@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family ade GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 ko:K01486 ko00230,ko01100,map00230,map01100 - R01244 RC00477 ko00000,ko00001,ko01000 - - - Adenine_deam_C,Amidohydro_1 SJTD3_k127_5714127_15 861299.J421_1831 1.037e-60 234.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.1.3.2 ko:K09474 ko00740,ko01100,ko02020,map00740,map01100,map02020 - R00548 RC00017 ko00000,ko00001,ko01000 - - - PAP2 SJTD3_k127_5714127_2 1340493.JNIF01000003_gene3500 5.553e-146 473.0 COG4948@1|root,COG4948@2|Bacteria 2|Bacteria M carboxylic acid catabolic process dgoD - 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N SJTD3_k127_5714127_7 266835.14026658 7.373e-98 332.0 COG1172@1|root,COG1172@2|Bacteria,1NQI8@1224|Proteobacteria,2URY1@28211|Alphaproteobacteria,43ND7@69277|Phyllobacteriaceae 28211|Alphaproteobacteria U Branched-chain amino acid transport system / permease component - - - ko:K10538 ko02010,map02010 M00213 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.2 - - BPD_transp_2 SJTD3_k127_5714127_1 1123023.JIAI01000002_gene4627 7.947e-155 505.0 COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4DYXK@85010|Pseudonocardiales 201174|Actinobacteria G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system rbsA - 3.6.3.17 ko:K10441,ko:K10539 ko02010,map02010 M00212,M00213 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.2 - - ABC_tran SJTD3_k127_5714127_13 266835.14026660 6.776e-68 245.0 COG1879@1|root,COG1879@2|Bacteria,1MVDG@1224|Proteobacteria,2TUFP@28211|Alphaproteobacteria,43ND5@69277|Phyllobacteriaceae 28211|Alphaproteobacteria G Periplasmic binding proteins and sugar binding domain of LacI family araF GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015399,GO:0015405,GO:0015407,GO:0015749,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042623,GO:0042626,GO:0043211,GO:0043492,GO:0044464,GO:0048029,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - ko:K10537 ko02010,map02010 M00213 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.2 - - Peripla_BP_1,Peripla_BP_4 SJTD3_k127_5714127_8 1040983.AXAE01000008_gene199 3.798e-95 317.0 COG1028@1|root,COG1028@2|Bacteria,1NTI2@1224|Proteobacteria,2U0CS@28211|Alphaproteobacteria 28211|Alphaproteobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 SJTD3_k127_5714127_6 1122237.AUGQ01000002_gene1786 3.583e-118 390.0 COG0673@1|root,COG0673@2|Bacteria,2IMUZ@201174|Actinobacteria 201174|Actinobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA SJTD3_k127_5714127_10 926550.CLDAP_15120 1.619e-81 284.0 COG0491@1|root,COG0491@2|Bacteria,2G8NI@200795|Chloroflexi 200795|Chloroflexi S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B SJTD3_k127_5714127_9 325452.fgenesh_scip_prom.46568.8020 1.937e-86 293.0 COG1024@1|root,COG1804@1|root,KOG1680@2759|Eukaryota,KOG3957@2759|Eukaryota,3Q8SW@4776|Peronosporales 2759|Eukaryota I Enoyl-CoA hydratase/isomerase - - - - - - - - - - - iEC55989_1330.EC55989_0038,iECIAI1_1343.ECIAI1_0040,iECO103_1326.ECO103_0040,iECO111_1330.ECO111_0039,iECO26_1355.ECO26_0039,iEcHS_1320.EcHS_A0042,iSF_1195.SF0035,iSFxv_1172.SFxv_0036,iS_1188.S0037 Acyl-CoA_dh_1,CoA_transf_3,ECH_1 SJTD3_k127_5714127_3 1120960.ATXG01000001_gene1208 2.129e-138 454.0 COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,4FRBJ@85023|Microbacteriaceae 201174|Actinobacteria C CoA-transferase family III - - - - - - - - - - - - CoA_transf_3 SJTD3_k127_5714127_17 1227453.C444_17922 6.879e-36 150.0 arCOG10324@1|root,arCOG10324@2157|Archaea,2XTPK@28890|Euryarchaeota,23U4J@183963|Halobacteria 183963|Halobacteria E unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - 3.2.1.172 ko:K15532 - - - - ko00000,ko01000 - GH105 - Glyco_hydro_88 SJTD3_k127_5714127_5 1120972.AUMH01000005_gene908 9.924e-128 415.0 COG0826@1|root,COG0826@2|Bacteria,1TT8S@1239|Firmicutes,4HCNE@91061|Bacilli 91061|Bacilli O Peptidase family U32 - - - - - - - - - - - - Peptidase_U32 SJTD3_k127_5714127_16 485913.Krac_0940 2.951e-54 200.0 COG2186@1|root,COG2186@2|Bacteria,2G9BA@200795|Chloroflexi 200795|Chloroflexi K FCD - - - - - - - - - - - - FCD,GntR SJTD3_k127_5714127_11 485913.Krac_10225 1.892e-81 281.0 COG5662@1|root,COG5662@2|Bacteria 2|Bacteria K AntiSigma factor - - - - - - - - - - - - zf-HC2 SJTD3_k127_5714127_14 485913.Krac_10224 2.461e-67 234.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_5714127_0 395965.Msil_2564 3.342e-161 524.0 COG3511@1|root,COG3511@2|Bacteria,1MVNS@1224|Proteobacteria,2U1QU@28211|Alphaproteobacteria,3NA31@45404|Beijerinckiaceae 28211|Alphaproteobacteria M Phosphoesterase family - - - - - - - - - - - - Phosphoesterase SJTD3_k127_5714127_4 105422.BBPM01000102_gene5262 4.407e-138 466.0 COG3055@1|root,COG3405@1|root,COG3055@2|Bacteria,COG3405@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - ASH SJTD3_k127_5714127_12 649638.Trad_0841 4.747e-79 269.0 COG3938@1|root,COG3938@2|Bacteria,1WMVD@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E Proline racemase - - 5.1.1.4 ko:K01777 ko00330,ko01100,map00330,map01100 - R01255 RC00479 ko00000,ko00001,ko01000 - - - Pro_racemase SJTD3_k127_5714127_20 266117.Rxyl_2251 3.015e-09 58.0 COG3938@1|root,COG3938@2|Bacteria,2GM47@201174|Actinobacteria,4CPQZ@84995|Rubrobacteria 84995|Rubrobacteria E Proline racemase - - 5.1.1.4 ko:K01777 ko00330,ko01100,map00330,map01100 - R01255 RC00479 ko00000,ko00001,ko01000 - - - Pro_racemase SJTD3_k127_5714127_19 935948.KE386494_gene485 3.878e-18 89.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,42F55@68295|Thermoanaerobacterales 186801|Clostridia K helix_turn _helix lactose operon repressor - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 SJTD3_k127_5714127_18 1532557.JL37_13455 1.432e-21 98.0 COG1454@1|root,COG1454@2|Bacteria,1RC9B@1224|Proteobacteria,2WDAC@28216|Betaproteobacteria,3T4TE@506|Alcaligenaceae 28216|Betaproteobacteria C Iron-containing alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH SJTD3_k127_5720318_0 1128421.JAGA01000002_gene331 2.828e-93 314.0 COG0442@1|root,COG0442@2|Bacteria,2NNNH@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit SJTD3_k127_5724942_3 324602.Caur_3075 5.416e-34 141.0 COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi,375VW@32061|Chloroflexia 32061|Chloroflexia H PFAM Thiamin pyrophosphokinase, catalytic region - - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic SJTD3_k127_5724942_1 357808.RoseRS_1035 6.794e-61 220.0 COG0566@1|root,COG0566@2|Bacteria,2G6MC@200795|Chloroflexi,376U0@32061|Chloroflexia 32061|Chloroflexia J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family - - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase SJTD3_k127_5724942_2 1157490.EL26_22525 1.114e-36 144.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli,279UH@186823|Alicyclobacillaceae 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 SJTD3_k127_5724942_4 1128421.JAGA01000002_gene74 1.857e-19 90.0 COG0291@1|root,COG0291@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p SJTD3_k127_5724942_0 479434.Sthe_2425 4.074e-69 252.0 COG1565@1|root,COG1565@2|Bacteria,2G8NS@200795|Chloroflexi,27Y3B@189775|Thermomicrobia 189775|Thermomicrobia S Putative S-adenosyl-L-methionine-dependent methyltransferase - - - - - - - - - - - - Methyltransf_28 SJTD3_k127_5768135_1 1128421.JAGA01000003_gene2771 8.262e-120 391.0 COG1653@1|root,COG1653@2|Bacteria 2|Bacteria G carbohydrate transport - - - ko:K02027 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - SBP_bac_1,SBP_bac_8 SJTD3_k127_5768135_3 1128421.JAGA01000003_gene2770 2.483e-110 366.0 COG1175@1|root,COG1175@2|Bacteria 2|Bacteria P transmembrane transport - - - ko:K02025,ko:K15771,ko:K17312 ko02010,map02010 M00207,M00491,M00604 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.15,3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 SJTD3_k127_5768135_2 1128421.JAGA01000003_gene2769 7.773e-114 374.0 COG0395@1|root,COG0395@2|Bacteria 2|Bacteria P glycerophosphodiester transmembrane transport - - - ko:K02026 - M00207 - - ko00000,ko00002,ko02000 3.A.1.1 - - BPD_transp_1 SJTD3_k127_5768135_0 1122223.KB890696_gene265 3.111e-135 439.0 COG3842@1|root,COG3842@2|Bacteria,1WJ3G@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus P TOBE domain - - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 SJTD3_k127_5768135_6 1132441.KI519454_gene1417 1.398e-17 90.0 2E4G6@1|root,32ZBB@2|Bacteria,2GR6E@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_5768135_4 485913.Krac_9259 3.714e-90 304.0 COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi 200795|Chloroflexi C PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - - - - - - - - - - FAD_binding_6,NAD_binding_1 SJTD3_k127_5768135_5 404589.Anae109_1055 2.315e-85 286.0 COG2041@1|root,COG2041@2|Bacteria,1MWZK@1224|Proteobacteria 1224|Proteobacteria S Oxidoreductase molybdopterin binding - - - - - - - - - - - - Oxidored_molyb SJTD3_k127_5768135_7 1280390.CBQR020000117_gene3081 4.41e-15 78.0 COG2227@1|root,COG2227@2|Bacteria,1UXZZ@1239|Firmicutes,4HG9W@91061|Bacilli,26XYA@186822|Paenibacillaceae 91061|Bacilli H Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_25 SJTD3_k127_5847811_0 246197.MXAN_5218 2.103e-09 70.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - GT87,PMT,PMT_2 SJTD3_k127_5847811_1 266779.Meso_4532 1.436e-05 49.0 COG2267@1|root,COG2267@2|Bacteria,1NJPZ@1224|Proteobacteria 1224|Proteobacteria I protein of Bacteria UniRef RepID - - - - - - - - - - - - DUF1749,Hydrolase_4 SJTD3_k127_5848073_0 309801.trd_1968 9.918e-170 567.0 COG0744@1|root,COG0744@2|Bacteria,2G5ZG@200795|Chloroflexi,27XN3@189775|Thermomicrobia 189775|Thermomicrobia M Transglycosylase - - - - - - - - - - - - Transgly,Transpeptidase SJTD3_k127_5856443_3 1380347.JNII01000005_gene3495 3.042e-32 127.0 COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria,4ETH6@85013|Frankiales 201174|Actinobacteria S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 SJTD3_k127_5856443_4 1538644.KO02_16790 1.172e-07 59.0 COG3189@1|root,COG3189@2|Bacteria,4NSFD@976|Bacteroidetes,1ITZH@117747|Sphingobacteriia 976|Bacteroidetes S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 SJTD3_k127_5856443_5 867845.KI911784_gene1952 3.116e-06 54.0 COG0695@1|root,COG0695@2|Bacteria 2|Bacteria O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins mrx1 - 1.20.4.3 ko:K18917 - - - - ko00000,ko01000 - - - Glutaredoxin SJTD3_k127_5856443_2 1382306.JNIM01000001_gene542 1.606e-108 358.0 COG0451@1|root,COG0451@2|Bacteria 2|Bacteria GM ADP-glyceromanno-heptose 6-epimerase activity - - - - - - - - - - - - Epimerase,NAD_binding_10 SJTD3_k127_5856443_1 1382306.JNIM01000001_gene2761 3.424e-144 462.0 COG1809@1|root,COG1809@2|Bacteria 2|Bacteria S phosphosulfolactate synthase activity - - - - - - - - - - - - ComA SJTD3_k127_5856443_0 472759.Nhal_3038 2.454e-187 597.0 COG2079@1|root,COG2079@2|Bacteria,1MUIG@1224|Proteobacteria,1RPQN@1236|Gammaproteobacteria 1236|Gammaproteobacteria S 2-methylcitrate dehydratase - - 4.2.1.79 ko:K01720 ko00640,map00640 - R04424 RC01152 ko00000,ko00001,ko01000 - - - MmgE_PrpD SJTD3_k127_5859043_1 1229780.BN381_100092 4.206e-111 366.0 COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria 201174|Actinobacteria C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - ko:K00372,ko:K02567 ko00910,ko01120,map00910,map01120 M00529,M00530,M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_5859043_2 525904.Tter_2538 1.02e-61 220.0 COG0437@1|root,COG0437@2|Bacteria 2|Bacteria C 4 iron, 4 sulfur cluster binding - - - - - - - - - - - - Fer4,Fer4_11,Fer4_4 SJTD3_k127_5859043_3 1254432.SCE1572_23385 3.291e-40 154.0 COG0723@1|root,COG0723@2|Bacteria 2|Bacteria C oxidoreductase activity, acting on diphenols and related substances as donors - - - - - - - - - - - - Rieske SJTD3_k127_5859043_0 1528106.JRJE01000005_gene1357 7.494e-117 387.0 COG0499@1|root,COG0499@2|Bacteria,1MUQ2@1224|Proteobacteria,2TSJY@28211|Alphaproteobacteria,2JPNJ@204441|Rhodospirillales 204441|Rhodospirillales H May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine - - 3.3.1.1 ko:K01251 ko00270,ko01100,map00270,map01100 M00035 R00192,R04936 RC00056,RC00069,RC01161,RC01243 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 - - - AdoHcyase,AdoHcyase_NAD SJTD3_k127_5859043_4 926550.CLDAP_28300 3.519e-22 96.0 COG2267@1|root,COG2267@2|Bacteria,2G6KF@200795|Chloroflexi 200795|Chloroflexi I Alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6 SJTD3_k127_5863681_0 1379270.AUXF01000001_gene1892 2.556e-108 353.0 COG5276@1|root,COG5276@2|Bacteria,1ZU8A@142182|Gemmatimonadetes 142182|Gemmatimonadetes S LVIVD repeat - - - - - - - - - - - - LVIVD SJTD3_k127_5870093_3 383372.Rcas_0127 1.153e-41 157.0 COG4813@1|root,COG4813@2|Bacteria,2G5QZ@200795|Chloroflexi 200795|Chloroflexi G Trehalose utilisation - - - - - - - - - - - - ThuA SJTD3_k127_5870093_1 485913.Krac_5266 1.797e-108 362.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C SJTD3_k127_5870093_4 446466.Cfla_1161 2.428e-24 114.0 COG0382@1|root,COG0382@2|Bacteria,2GJT3@201174|Actinobacteria,4F157@85016|Cellulomonadaceae 201174|Actinobacteria H UbiA prenyltransferase family ubiA - - - - - - - - - - - UbiA SJTD3_k127_5870093_2 1128421.JAGA01000002_gene1172 7.712e-107 363.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups mtfA - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_5870093_0 326427.Cagg_2454 2.598e-130 424.0 COG0438@1|root,COG0438@2|Bacteria,2G7XU@200795|Chloroflexi,3755Q@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glycos_transf_1 SJTD3_k127_5870093_6 1121405.dsmv_2025 8.44e-15 76.0 COG3478@1|root,COG3478@2|Bacteria,1P0EH@1224|Proteobacteria,431E0@68525|delta/epsilon subdivisions,2WWIK@28221|Deltaproteobacteria,2MNXS@213118|Desulfobacterales 28221|Deltaproteobacteria S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - - - - - - - - - - - SJTD3_k127_5870093_5 479434.Sthe_1325 1.14e-17 85.0 2EU3R@1|root,33MKI@2|Bacteria,2G9PI@200795|Chloroflexi 200795|Chloroflexi - - - - - - - - - - - - - - - SJTD3_k127_5885652_0 485913.Krac_6032 2.452e-162 535.0 COG4585@1|root,COG4585@2|Bacteria,2G88D@200795|Chloroflexi 200795|Chloroflexi T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - GAF_2,GAF_3,HATPase_c,HisKA_3 SJTD3_k127_5885652_1 485913.Krac_6031 5.214e-34 132.0 COG2197@1|root,COG2197@2|Bacteria 2|Bacteria K response regulator - - - - - - - - - - - - GerE,Response_reg SJTD3_k127_5888400_1 479434.Sthe_1490 1.179e-213 677.0 COG0488@1|root,COG0488@2|Bacteria,2G5VD@200795|Chloroflexi,27XQY@189775|Thermomicrobia 200795|Chloroflexi S ABC transporter - - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn SJTD3_k127_5888400_0 197221.22294299 9.921e-281 884.0 COG0296@1|root,COG0296@2|Bacteria,1G1IW@1117|Cyanobacteria 1117|Cyanobacteria G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB - 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 iJN678.glgB Alpha-amylase,Alpha-amylase_C,CBM_48 SJTD3_k127_5888400_7 673860.AciM339_1041 1.652e-09 62.0 arCOG03672@1|root,arCOG08126@1|root,arCOG03672@2157|Archaea,arCOG08126@2157|Archaea,2Y73H@28890|Euryarchaeota,3F3BZ@33867|unclassified Euryarchaeota 28890|Euryarchaeota S Phospholipase_D-nuclease N-terminal - - - - - - - - - - - - PLDc_N SJTD3_k127_5888400_2 1054860.KB913030_gene6340 5.868e-66 236.0 COG0697@1|root,COG0697@2|Bacteria,2I9UQ@201174|Actinobacteria 201174|Actinobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA SJTD3_k127_5888400_4 113355.CM001775_gene2931 3.95e-57 216.0 COG2304@1|root,COG2304@2|Bacteria,1G1BE@1117|Cyanobacteria 1117|Cyanobacteria S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - Macro,VWA SJTD3_k127_5888400_6 215803.DB30_6313 4.84e-11 72.0 COG0789@1|root,COG0789@2|Bacteria,1Q71A@1224|Proteobacteria,433UC@68525|delta/epsilon subdivisions,2XA1C@28221|Deltaproteobacteria,2YW54@29|Myxococcales 28221|Deltaproteobacteria K helix_turn_helix, mercury resistance - - - - - - - - - - - - MerR_1 SJTD3_k127_5888400_3 485913.Krac_1566 2.697e-57 210.0 COG3177@1|root,COG3177@2|Bacteria,2G7KD@200795|Chloroflexi 200795|Chloroflexi S Fic/DOC family - - - - - - - - - - - - Fic SJTD3_k127_5890748_5 1382356.JQMP01000001_gene991 6.08e-50 191.0 COG0823@1|root,COG0823@2|Bacteria,2G8Z9@200795|Chloroflexi,27XTF@189775|Thermomicrobia 189775|Thermomicrobia U Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 SJTD3_k127_5890748_3 485913.Krac_8325 2.127e-74 265.0 COG2348@1|root,COG2348@2|Bacteria,2G6KK@200795|Chloroflexi 200795|Chloroflexi V PFAM Methicillin resistance protein - - - - - - - - - - - - FemAB SJTD3_k127_5890748_7 118163.Ple7327_1591 1.059e-35 147.0 COG1432@1|root,COG1432@2|Bacteria,1G01P@1117|Cyanobacteria,3VIQD@52604|Pleurocapsales 1117|Cyanobacteria S NYN domain - - - - - - - - - - - - NYN SJTD3_k127_5890748_4 309801.trd_0928 3.279e-59 218.0 COG1413@1|root,COG1413@2|Bacteria,2G6MW@200795|Chloroflexi,27Y7K@189775|Thermomicrobia 189775|Thermomicrobia C PBS lyase HEAT-like repeat - - - - - - - - - - - - HEAT_2 SJTD3_k127_5890748_2 525904.Tter_0953 3.239e-82 302.0 COG3170@1|root,COG3170@2|Bacteria,2NQGZ@2323|unclassified Bacteria 2|Bacteria NU Tfp pilus assembly protein FimV - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - DUF1631 SJTD3_k127_5890748_8 1121428.DESHY_30022___1 2.653e-23 107.0 COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,2633R@186807|Peptococcaceae 186801|Clostridia D Protein of unknown function (DUF4446) - - - - - - - - - - - - DUF4446 SJTD3_k127_5890748_1 1382306.JNIM01000001_gene3678 1.857e-99 337.0 COG0501@1|root,COG0501@2|Bacteria,2G6KE@200795|Chloroflexi 200795|Chloroflexi O PFAM peptidase M48 Ste24p - - 3.4.24.84 ko:K06013 ko00900,ko01130,map00900,map01130 - R09845 RC00141 ko00000,ko00001,ko01000,ko01002,ko04147 - - - Peptidase_M48,Peptidase_M48_N SJTD3_k127_5890748_11 1536775.H70737_16625 4.059e-11 75.0 COG0640@1|root,COG0640@2|Bacteria,1V1HY@1239|Firmicutes,4HG51@91061|Bacilli,26RZX@186822|Paenibacillaceae 91061|Bacilli K ArsR family transcriptional regulator - - - - - - - - - - - - HTH_20,HTH_5 SJTD3_k127_5890748_9 926569.ANT_29300 4.376e-21 109.0 COG1216@1|root,COG1216@2|Bacteria,2G9RD@200795|Chloroflexi 200795|Chloroflexi S Glycosyl transferase, family 2 - - - - - - - - - - - - - SJTD3_k127_5890748_12 1206730.BAGA01000093_gene462 8.748e-10 71.0 COG0515@1|root,COG3903@1|root,COG0515@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FUTU@85025|Nocardiaceae 201174|Actinobacteria K activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - 2.7.11.1 ko:K08282,ko:K13419 - - - - ko00000,ko01000,ko01001 - - - AAA_22,GerE,NB-ARC,Pkinase,TPR_7 SJTD3_k127_5890748_10 1444309.JAQG01000021_gene1421 3.294e-18 96.0 COG3502@1|root,COG3502@2|Bacteria,1V8W5@1239|Firmicutes,4HJGW@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF952) - - - - - - - - - - - - DUF952 SJTD3_k127_5890748_6 1297742.A176_01429 5.58e-45 172.0 COG0125@1|root,COG0125@2|Bacteria,1MV9C@1224|Proteobacteria,42RK3@68525|delta/epsilon subdivisions,2WN3N@28221|Deltaproteobacteria,2YVHP@29|Myxococcales 28221|Deltaproteobacteria F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk - 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Thymidylate_kin SJTD3_k127_5890748_0 525904.Tter_2251 8.625e-109 360.0 COG1131@1|root,COG1131@2|Bacteria,2NP0I@2323|unclassified Bacteria 2|Bacteria V ATPases associated with a variety of cellular activities - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SJTD3_k127_5890748_13 1337936.IJ00_09695 7.437e-05 47.0 COG0842@1|root,COG0842@2|Bacteria,1G3G7@1117|Cyanobacteria,1HKC0@1161|Nostocales 1117|Cyanobacteria U Transport permease protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane SJTD3_k127_5893590_0 1382356.JQMP01000004_gene653 9.276e-35 152.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_5900706_2 645991.Sgly_2736 4.277e-61 222.0 COG4552@1|root,COG4552@2|Bacteria,1TRPM@1239|Firmicutes 1239|Firmicutes S Acetyltransferase involved in intracellular survival and related - - - - - - - - - - - - Acetyltransf_9,SCP2_2 SJTD3_k127_5900706_0 479434.Sthe_1848 1.412e-101 346.0 COG1253@1|root,COG1253@2|Bacteria,2G6DE@200795|Chloroflexi,27YYU@189775|Thermomicrobia 189775|Thermomicrobia S Transporter associated domain - - - - - - - - - - - - CBS,CorC_HlyC,DUF21 SJTD3_k127_5900706_1 479434.Sthe_1249 5.017e-86 303.0 COG0747@1|root,COG0747@2|Bacteria,2G5NC@200795|Chloroflexi,27XPP@189775|Thermomicrobia 189775|Thermomicrobia E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SJTD3_k127_5908597_2 765420.OSCT_1726 2.107e-29 133.0 COG5617@1|root,COG5617@2|Bacteria,2GAHU@200795|Chloroflexi,3767W@32061|Chloroflexia 32061|Chloroflexia S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - SJTD3_k127_5908597_1 765420.OSCT_2256 1.63e-134 445.0 COG0195@1|root,COG0195@2|Bacteria,2G5M5@200795|Chloroflexi,3756H@32061|Chloroflexia 32061|Chloroflexia K Participates in both transcription termination and antitermination nusA - - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 SJTD3_k127_5908597_4 479434.Sthe_1256 1.709e-24 107.0 COG2740@1|root,COG2740@2|Bacteria,2G72H@200795|Chloroflexi,27YHF@189775|Thermomicrobia 189775|Thermomicrobia K Protein of unknown function (DUF448) - - - ko:K07742 - - - - ko00000 - - - DUF448 SJTD3_k127_5908597_0 479434.Sthe_1257 1.794e-225 718.0 COG0532@1|root,COG0532@2|Bacteria,2G5UR@200795|Chloroflexi,27XWF@189775|Thermomicrobia 189775|Thermomicrobia J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB - - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N SJTD3_k127_5908597_3 479434.Sthe_1258 1.926e-27 117.0 COG0858@1|root,COG0858@2|Bacteria,2G73E@200795|Chloroflexi,27YJU@189775|Thermomicrobia 189775|Thermomicrobia J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA SJTD3_k127_5908597_5 370438.PTH_1271 6.275e-05 53.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,261DN@186807|Peptococcaceae 186801|Clostridia S DHHA1 domain nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 SJTD3_k127_5910736_5 526227.Mesil_2664 1.384e-58 208.0 COG5504@1|root,COG5504@2|Bacteria,1WMJ7@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus O Predicted Zn-dependent protease (DUF2268) - - - - - - - - - - - - DUF2268 SJTD3_k127_5910736_6 1128421.JAGA01000002_gene486 6.486e-54 199.0 COG1381@1|root,COG1381@2|Bacteria,2NPV3@2323|unclassified Bacteria 2|Bacteria L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N SJTD3_k127_5910736_1 1345697.M493_11910 2.705e-94 318.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli,1WE42@129337|Geobacillus 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 SJTD3_k127_5910736_7 1120949.KB903339_gene7992 2.405e-37 146.0 2DMR3@1|root,32T4S@2|Bacteria,2I7IG@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_5910736_0 498761.HM1_0890 1.454e-162 539.0 COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,1TPG1@1239|Firmicutes,24BBE@186801|Clostridia 186801|Clostridia C Fe-S oxidoreductase - - - - - - - - - - - - CCG,Fer4_8 SJTD3_k127_5910736_8 1123368.AUIS01000004_gene233 3.584e-26 117.0 2E7CK@1|root,331VT@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5910736_9 1236542.BALM01000008_gene2881 2.971e-22 108.0 28TMI@1|root,30GG2@2|Bacteria,1RE0D@1224|Proteobacteria,1S0JA@1236|Gammaproteobacteria,2QBEE@267890|Shewanellaceae 1236|Gammaproteobacteria S Spondin_N - - - - - - - - - - - - Spond_N SJTD3_k127_5910736_3 1120949.KB903356_gene8773 1.329e-66 239.0 COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,4DA2B@85008|Micromonosporales 201174|Actinobacteria C electron transfer flavoprotein, alpha subunit etfA GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03522 - - - - ko00000,ko04147 - - - ETF,ETF_alpha SJTD3_k127_5910736_4 469371.Tbis_2846 3.065e-66 234.0 COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4E0JQ@85010|Pseudonocardiales 201174|Actinobacteria C Electron transfer flavoprotein etfB GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - ko:K03521 - - - - ko00000 - - - ETF SJTD3_k127_5910736_2 264732.Moth_2046 7.105e-70 243.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,42EPI@68295|Thermoanaerobacterales 186801|Clostridia F PFAM AIR synthase related protein purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C SJTD3_k127_5911086_0 525904.Tter_2366 2.596e-176 568.0 COG2268@1|root,COG2268@2|Bacteria,2NPBZ@2323|unclassified Bacteria 2|Bacteria S prohibitin homologues - - - ko:K07192 ko04910,map04910 - - - ko00000,ko00001,ko03036,ko04131,ko04147 - - - Band_7,Flot SJTD3_k127_5911086_1 234267.Acid_4572 2.596e-28 123.0 COG1585@1|root,COG1585@2|Bacteria,3Y4Y0@57723|Acidobacteria 57723|Acidobacteria OU Membrane protein implicated in regulation of membrane protease activity - - - - - - - - - - - - - SJTD3_k127_5926097_2 1382356.JQMP01000004_gene485 8.263e-52 186.0 COG0366@1|root,COG0366@2|Bacteria,2G89J@200795|Chloroflexi,27XYW@189775|Thermomicrobia 189775|Thermomicrobia G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB glgE - 2.4.99.16 ko:K16147 ko00500,ko01100,map00500,map01100 - R09994 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3416 SJTD3_k127_5926097_0 479434.Sthe_1092 3.76e-118 399.0 COG0366@1|root,COG3281@1|root,COG0366@2|Bacteria,COG3281@2|Bacteria,2G86T@200795|Chloroflexi,27XQK@189775|Thermomicrobia 189775|Thermomicrobia G Alpha-amylase domain - - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - APH,Alpha-amylase,Malt_amylase_C SJTD3_k127_5926097_1 383372.Rcas_2505 4.135e-61 235.0 COG1807@1|root,COG1807@2|Bacteria,2G8IK@200795|Chloroflexi,375EI@32061|Chloroflexia 32061|Chloroflexia M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - - SJTD3_k127_5936634_1 65497.JODV01000014_gene3394 1.105e-43 172.0 COG1192@1|root,COG1192@2|Bacteria,2GJX3@201174|Actinobacteria,4DXSW@85010|Pseudonocardiales 201174|Actinobacteria D involved in chromosome partitioning soj GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 SJTD3_k127_5936634_0 485913.Krac_5109 3.195e-63 230.0 COG1475@1|root,COG1475@2|Bacteria,2G9AU@200795|Chloroflexi 200795|Chloroflexi K ParB-like nuclease domain - - - - - - - - - - - - ParBc SJTD3_k127_5938784_5 1121382.JQKG01000006_gene3450 1.013e-06 52.0 COG3250@1|root,COG3250@2|Bacteria 2|Bacteria G beta-galactosidase activity manB2 - 3.2.1.25 ko:K01192 ko00511,ko04142,map00511,map04142 - - - ko00000,ko00001,ko01000 - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N SJTD3_k127_5938784_3 1120950.KB892751_gene6788 4.477e-90 307.0 COG4608@1|root,COG4608@2|Bacteria,2IBD7@201174|Actinobacteria,4DTRV@85009|Propionibacteriales 201174|Actinobacteria E ATPases associated with a variety of cellular activities - - - ko:K02032 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY SJTD3_k127_5938784_1 390989.JOEG01000035_gene1752 3.73e-117 386.0 COG0444@1|root,COG0444@2|Bacteria,2IAWG@201174|Actinobacteria,4DI3E@85008|Micromonosporales 201174|Actinobacteria EP Oligopeptide/dipeptide transporter, C-terminal region - - - ko:K02031 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - ABC_tran,oligo_HPY SJTD3_k127_5938784_2 390989.JOEG01000035_gene1751 3.753e-106 352.0 COG1173@1|root,COG1173@2|Bacteria,2GMJC@201174|Actinobacteria,4DH5Z@85008|Micromonosporales 201174|Actinobacteria EP Binding-protein-dependent transport system inner membrane component - - - ko:K02034 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 SJTD3_k127_5938784_0 1463821.JOGR01000005_gene2980 6.925e-130 422.0 COG0601@1|root,COG0601@2|Bacteria,2GM72@201174|Actinobacteria 201174|Actinobacteria EP PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K02033 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - BPD_transp_1 SJTD3_k127_5938784_4 543632.JOJL01000039_gene1595 2.283e-45 167.0 COG0747@1|root,COG0747@2|Bacteria,2I9MB@201174|Actinobacteria,4DI57@85008|Micromonosporales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SJTD3_k127_5942504_1 219305.MCAG_04356 4.144e-71 252.0 COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,4D8XR@85008|Micromonosporales 201174|Actinobacteria H Belongs to the ribF family ribF GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - FAD_syn,Flavokinase SJTD3_k127_5942504_0 136993.KB900627_gene447 3.086e-88 304.0 COG2706@1|root,COG2706@2|Bacteria,1NG69@1224|Proteobacteria 1224|Proteobacteria G Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Lactonase SJTD3_k127_5942504_4 1121087.AUCK01000014_gene339 1.766e-05 55.0 COG4942@1|root,COG4942@2|Bacteria,1TQ5I@1239|Firmicutes,4HB9Q@91061|Bacilli,1ZBKA@1386|Bacillus 91061|Bacilli D peptidase - - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_M23 SJTD3_k127_5942504_2 236097.ADG881_168 6.507e-31 126.0 COG0551@1|root,COG0551@2|Bacteria,1RJ5B@1224|Proteobacteria,1S349@1236|Gammaproteobacteria 1236|Gammaproteobacteria L Zn-finger domain associated with topoisomerase type I - - - - - - - - - - - - DUF2726,zf-C4_Topoisom SJTD3_k127_5953671_0 485913.Krac_7202 4.049e-87 304.0 COG0477@1|root,COG2814@2|Bacteria,2G8CV@200795|Chloroflexi 2|Bacteria EGP PFAM major facilitator superfamily MFS_1 - - - - - - - - - - - - MFS_1,MFS_3 SJTD3_k127_5959203_2 1382306.JNIM01000001_gene1073 1.026e-20 100.0 COG0075@1|root,COG0075@2|Bacteria,2G5P3@200795|Chloroflexi 200795|Chloroflexi E PFAM aminotransferase class V - - - - - - - - - - - - Aminotran_5 SJTD3_k127_5959203_1 1000565.METUNv1_01440 1.042e-46 189.0 COG0560@1|root,COG0560@2|Bacteria 2|Bacteria E Phosphoserine phosphatase - - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD,Hydrolase SJTD3_k127_5959203_0 266117.Rxyl_0837 1.962e-84 302.0 COG1052@1|root,COG1052@2|Bacteria,2I2RK@201174|Actinobacteria,4CU65@84995|Rubrobacteria 84995|Rubrobacteria C D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT SJTD3_k127_5969103_0 1123368.AUIS01000005_gene431 1.031e-217 681.0 COG0243@1|root,COG0243@2|Bacteria,1NS3T@1224|Proteobacteria,1RMWN@1236|Gammaproteobacteria 1236|Gammaproteobacteria C Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism narB - - ko:K00372 ko00910,ko01120,map00910,map01120 M00531 R00798,R01106 RC02812 ko00000,ko00001,ko00002,ko01000 - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_5969103_2 1123276.KB893263_gene4681 1.592e-27 129.0 2CJDS@1|root,32QT3@2|Bacteria,4P3VJ@976|Bacteroidetes 976|Bacteroidetes - - - - - - - - - - - - - - - SJTD3_k127_5969103_1 1123368.AUIS01000005_gene434 1.291e-39 167.0 COG3448@1|root,COG3448@2|Bacteria,1MYEK@1224|Proteobacteria,1SIHU@1236|Gammaproteobacteria 1236|Gammaproteobacteria T HPP family - - - - - - - - - - - - HPP SJTD3_k127_5969103_3 1128421.JAGA01000003_gene3253 1.982e-24 115.0 COG0726@1|root,COG0726@2|Bacteria,2NPV2@2323|unclassified Bacteria 2|Bacteria G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - LysM,Polysacc_deac_1 SJTD3_k127_5971030_1 383372.Rcas_0293 2.043e-34 154.0 COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi,3757B@32061|Chloroflexia 32061|Chloroflexia O PFAM NHL repeat containing protein - - - - - - - - - - - - NHL,PMT_2 SJTD3_k127_5971030_0 316274.Haur_2537 2.603e-62 244.0 COG5427@1|root,COG5427@2|Bacteria,2G6AA@200795|Chloroflexi,37682@32061|Chloroflexia 32061|Chloroflexia S Uncharacterized membrane protein (DUF2298) - - - - - - - - - - - - DUF2298 SJTD3_k127_5982929_0 765420.OSCT_1953 1.112e-91 319.0 COG2203@1|root,COG3605@1|root,COG3920@1|root,COG2203@2|Bacteria,COG3605@2|Bacteria,COG3920@2|Bacteria,2G67M@200795|Chloroflexi,374WN@32061|Chloroflexia 32061|Chloroflexia T ATP-binding region, ATPase domain protein - - - - - - - - - - - - GAF,GAF_2,HATPase_c_2,HisKA_2 SJTD3_k127_5982929_1 40041.SZO_08500 1.045e-65 233.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli,1M8UF@119603|Streptococcus dysgalactiae group 91061|Bacilli V ATP-binding protein salX - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran SJTD3_k127_5982929_3 247490.KSU1_C0362 8.71e-10 66.0 arCOG13241@1|root,2ZEFN@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_5982929_2 1382356.JQMP01000003_gene1940 1.34e-61 225.0 COG0791@1|root,COG3103@1|root,COG0791@2|Bacteria,COG4991@2|Bacteria,2G99E@200795|Chloroflexi,27XPH@189775|Thermomicrobia 189775|Thermomicrobia MT NlpC/P60 family - - - - - - - - - - - - NLPC_P60,SH3_3 SJTD3_k127_5989947_0 1382356.JQMP01000003_gene1524 6.444e-154 494.0 COG0174@1|root,COG0174@2|Bacteria,2G5U2@200795|Chloroflexi,27XSZ@189775|Thermomicrobia 189775|Thermomicrobia E glutamine synthetase - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N SJTD3_k127_5989947_1 485913.Krac_10094 2.304e-72 253.0 COG0639@1|root,COG0639@2|Bacteria 2|Bacteria T phosphoprotein phosphatase activity - - - - - - - - - - - - Metallophos SJTD3_k127_5990622_3 479434.Sthe_0414 2.378e-17 91.0 COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,27XKY@189775|Thermomicrobia 189775|Thermomicrobia L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 SJTD3_k127_5990622_0 479434.Sthe_0729 1.005e-142 470.0 COG0568@1|root,COG0568@2|Bacteria,2G5W3@200795|Chloroflexi,27XEZ@189775|Thermomicrobia 189775|Thermomicrobia K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth - - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 SJTD3_k127_5990622_2 358396.C445_05123 2.567e-34 139.0 COG3358@1|root,arCOG04570@2157|Archaea,2XX3J@28890|Euryarchaeota,23VM5@183963|Halobacteria 183963|Halobacteria S Protein of unknown function (DUF1684) - - - ko:K09164 - - - - ko00000 - - - DUF1684 SJTD3_k127_5990622_1 1144275.COCOR_05745 4.747e-70 246.0 COG0846@1|root,COG0846@2|Bacteria,1MUK1@1224|Proteobacteria,42QVM@68525|delta/epsilon subdivisions,2WN3E@28221|Deltaproteobacteria,2YTVS@29|Myxococcales 28221|Deltaproteobacteria K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form cobB - - ko:K12410 - - - - ko00000,ko01000 - - - SIR2 SJTD3_k127_5993894_3 66897.DJ64_34025 5.396e-08 57.0 COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria 201174|Actinobacteria L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 SJTD3_k127_5993894_1 316274.Haur_4963 3.432e-40 154.0 COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi,375QY@32061|Chloroflexia 32061|Chloroflexia L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB SJTD3_k127_5993894_0 479434.Sthe_0439 5.499e-67 248.0 COG1686@1|root,COG1686@2|Bacteria,2G8TU@200795|Chloroflexi,27XVX@189775|Thermomicrobia 189775|Thermomicrobia M Belongs to the peptidase S11 family - - 3.4.16.4 ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - Peptidase_S11 SJTD3_k127_5997746_1 485913.Krac_7491 2.015e-20 99.0 COG1073@1|root,COG1073@2|Bacteria 2|Bacteria S thiolester hydrolase activity - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 SJTD3_k127_5997746_0 479434.Sthe_0109 1.168e-54 200.0 COG0412@1|root,COG0412@2|Bacteria,2G8NW@200795|Chloroflexi 200795|Chloroflexi Q PFAM Dienelactone hydrolase - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH SJTD3_k127_5997746_2 867845.KI911784_gene1050 2.398e-11 64.0 2CMS6@1|root,32SFE@2|Bacteria,2G905@200795|Chloroflexi,377IA@32061|Chloroflexia 32061|Chloroflexia S DinB superfamily - - - - - - - - - - - - DinB_2 SJTD3_k127_6000083_1 709986.Deima_2595 5.473e-43 181.0 COG4585@1|root,COG4585@2|Bacteria,1WJNH@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - - - - - - - - - - GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3,PAS,PAS_4,PAS_8 SJTD3_k127_6000083_0 243164.DET0136 4.618e-112 379.0 COG4191@1|root,COG5002@1|root,COG4191@2|Bacteria,COG5002@2|Bacteria,2G67W@200795|Chloroflexi,34D12@301297|Dehalococcoidia 301297|Dehalococcoidia T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,sCache_like SJTD3_k127_6000719_0 326427.Cagg_2982 7.714e-154 502.0 COG4962@1|root,COG4962@2|Bacteria,2G7K7@200795|Chloroflexi,3759Z@32061|Chloroflexia 32061|Chloroflexia U PFAM type II secretion system protein E - - - ko:K02283 - - - - ko00000,ko02035,ko02044 - - - T2SSE SJTD3_k127_6011811_1 710696.Intca_2865 8.813e-44 169.0 COG0546@1|root,COG0546@2|Bacteria,2I9FC@201174|Actinobacteria,4FGUD@85021|Intrasporangiaceae 201174|Actinobacteria S HAD family hydrolase - - 3.1.3.18,3.6.1.1 ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 SJTD3_k127_6011811_2 1068978.AMETH_7055 3.598e-25 110.0 COG1051@1|root,COG1051@2|Bacteria,2I2DG@201174|Actinobacteria,4E30H@85010|Pseudonocardiales 201174|Actinobacteria F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX SJTD3_k127_6011811_0 1118054.CAGW01000021_gene4111 2.482e-113 379.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli,26QKI@186822|Paenibacillaceae 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 SJTD3_k127_6013891_1 1382356.JQMP01000004_gene494 7.286e-43 163.0 COG0771@1|root,COG0771@2|Bacteria,2GBHB@200795|Chloroflexi,27XXI@189775|Thermomicrobia 189775|Thermomicrobia M Domain of unknown function (DUF1727) - - - - - - - - - - - - DUF1727,Mur_ligase_M SJTD3_k127_6013891_2 411464.DESPIG_00584 1.398e-07 62.0 COG1579@1|root,COG1579@2|Bacteria,1R7GT@1224|Proteobacteria,42P3S@68525|delta/epsilon subdivisions,2WKVG@28221|Deltaproteobacteria,2M888@213115|Desulfovibrionales 28221|Deltaproteobacteria S C4-type zinc ribbon domain - - - ko:K07164 - - - - ko00000 - - - zf-RING_7 SJTD3_k127_6013891_0 926560.KE387026_gene4276 6.851e-78 271.0 COG1175@1|root,COG1175@2|Bacteria 2|Bacteria P transmembrane transport - - - ko:K02025,ko:K15771 ko02010,map02010 M00207,M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1,3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 SJTD3_k127_6015790_0 357808.RoseRS_0120 4.136e-36 155.0 COG0457@1|root,COG0457@2|Bacteria,2G81B@200795|Chloroflexi,375DZ@32061|Chloroflexia 32061|Chloroflexia M Tetratricopeptide repeat - - - - - - - - - - - - - SJTD3_k127_6017740_1 326427.Cagg_1399 1.06e-28 126.0 COG0457@1|root,COG0457@2|Bacteria,2G9ET@200795|Chloroflexi,377NS@32061|Chloroflexia 32061|Chloroflexia NU Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - TPR_1,TPR_11,TPR_16,TPR_2,TPR_8 SJTD3_k127_6017740_0 1382306.JNIM01000001_gene861 7.045e-202 641.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi 200795|Chloroflexi F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB - 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH SJTD3_k127_6021690_0 323850.Shew_3239 1.571e-128 435.0 COG2373@1|root,COG3055@1|root,COG3386@1|root,COG2373@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,1N85X@1224|Proteobacteria,1T3ZR@1236|Gammaproteobacteria,2QEVC@267890|Shewanellaceae 1224|Proteobacteria M PFAM Na-Ca exchanger integrin-beta4 - - - - - - - - - - - - - SJTD3_k127_6032977_1 543632.JOJL01000038_gene3143 1.077e-41 174.0 COG4447@1|root,COG4447@2|Bacteria,2IT8P@201174|Actinobacteria 201174|Actinobacteria M phospholipase C - - - - - - - - - - - - - SJTD3_k127_6032977_3 714961.BFZC1_04803 1.018e-14 88.0 COG4632@1|root,COG5184@1|root,COG4632@2|Bacteria,COG5184@2|Bacteria,1UMUN@1239|Firmicutes,4IU0J@91061|Bacilli,3IYGB@400634|Lysinibacillus 91061|Bacilli G S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_6032977_2 1038869.AXAN01000047_gene4503 1.456e-33 151.0 COG4409@1|root,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - ASH,BNR_2,Big_3_2,CBM_35,DUF1080,F5_F8_type_C,PKD,RicinB_lectin_2,Trehalase SJTD3_k127_6032977_0 1120950.KB892746_gene3462 1.998e-53 216.0 COG4447@1|root,COG4447@2|Bacteria,2I9D0@201174|Actinobacteria,4DSNJ@85009|Propionibacteriales 201174|Actinobacteria S cellulose binding - - - - - - - - - - - - - SJTD3_k127_6034853_0 269797.Mbar_A2460 5.161e-72 256.0 COG0500@1|root,arCOG01791@2157|Archaea,2Y66M@28890|Euryarchaeota,2NAUT@224756|Methanomicrobia 224756|Methanomicrobia Q Tellurite resistance protein TehB - - - - - - - - - - - - Methyltransf_25 SJTD3_k127_6034853_2 614083.AWQR01000047_gene3277 1.718e-54 217.0 COG2202@1|root,COG4585@1|root,COG5002@1|root,COG2202@2|Bacteria,COG4585@2|Bacteria,COG5002@2|Bacteria,1N1PW@1224|Proteobacteria,2VU49@28216|Betaproteobacteria 28216|Betaproteobacteria T histidine kinase, dimerisation and phosphoacceptor region - - - - - - - - - - - - HATPase_c,HisKA_3 SJTD3_k127_6034853_1 338969.Rfer_0894 6.257e-69 240.0 COG2197@1|root,COG2197@2|Bacteria,1RH8D@1224|Proteobacteria,2WEH4@28216|Betaproteobacteria,4AIYX@80864|Comamonadaceae 28216|Betaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg SJTD3_k127_6040085_1 748280.NH8B_3133 1.455e-34 138.0 COG4932@1|root,COG4932@2|Bacteria,1R944@1224|Proteobacteria 1224|Proteobacteria M domain protein - - - - - - - - - - - - - SJTD3_k127_6040085_2 926569.ANT_18860 5.207e-14 78.0 COG3743@1|root,COG3743@2|Bacteria,2G96D@200795|Chloroflexi 200795|Chloroflexi S Domain of unknown function (DUF4332) - - - - - - - - - - - - DUF4332 SJTD3_k127_6040085_0 765420.OSCT_2238 8.877e-37 148.0 COG2267@1|root,COG2267@2|Bacteria,2G75K@200795|Chloroflexi 200795|Chloroflexi I Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 SJTD3_k127_6040364_1 42256.RradSPS_0871 3.171e-70 242.0 COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,4CQ5F@84995|Rubrobacteria 84995|Rubrobacteria C F420-0:Gamma-glutamyl ligase - - 6.3.2.31,6.3.2.34 ko:K12234 ko00680,ko01120,map00680,map01120 M00378 R09399,R09400 RC00064,RC00090,RC00141 ko00000,ko00001,ko00002,ko01000 - - - F420_ligase SJTD3_k127_6040364_0 485913.Krac_1241 8.781e-89 303.0 COG2141@1|root,COG2141@2|Bacteria 2|Bacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase SJTD3_k127_6045584_2 357808.RoseRS_2703 5.212e-24 112.0 COG2304@1|root,COG2304@2|Bacteria,2GACU@200795|Chloroflexi,375FC@32061|Chloroflexia 32061|Chloroflexia S PFAM von Willebrand factor type A - - - - - - - - - - - - BatA,VWA_2 SJTD3_k127_6045584_1 357808.RoseRS_1889 9.827e-49 188.0 COG1721@1|root,COG1721@2|Bacteria,2GACI@200795|Chloroflexi,375AS@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function DUF58 - - - - - - - - - - - - DUF58 SJTD3_k127_6045584_0 1521187.JPIM01000176_gene933 2.717e-122 402.0 COG0714@1|root,COG0714@2|Bacteria,2GACN@200795|Chloroflexi,375BZ@32061|Chloroflexia 32061|Chloroflexia S PFAM ATPase associated with various cellular activities, AAA_3 - - - ko:K03924 - - - - ko00000,ko01000 - - - AAA_3 SJTD3_k127_6045584_3 1128421.JAGA01000002_gene1761 1.098e-12 81.0 COG1511@1|root,COG1511@2|Bacteria 2|Bacteria Q domain protein - - - - - - - - - - - - DUF802,TPM_phosphatase SJTD3_k127_6046139_0 867845.KI911784_gene3026 1.758e-118 391.0 COG0403@1|root,COG0403@2|Bacteria,2G5NI@200795|Chloroflexi,376C6@32061|Chloroflexia 32061|Chloroflexia C The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor gcvPA - 1.4.4.2 ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 - R01221,R03425 RC00022,RC00929,RC02834,RC02880 ko00000,ko00001,ko01000 - - - GDC-P SJTD3_k127_6046139_3 1499968.TCA2_3392 1.101e-08 64.0 COG1051@1|root,COG1051@2|Bacteria,1V3T8@1239|Firmicutes,4HH2F@91061|Bacilli,26WQM@186822|Paenibacillaceae 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX SJTD3_k127_6046139_2 525904.Tter_1497 1.59e-39 152.0 COG0509@1|root,COG0509@2|Bacteria,2NPMR@2323|unclassified Bacteria 2|Bacteria E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein gcvH - - ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 M00532 R01221 RC00022,RC02834 ko00000,ko00001,ko00002 - - - GCV_H SJTD3_k127_6046139_1 1120973.AQXL01000127_gene2716 8.423e-54 196.0 COG0404@1|root,COG0404@2|Bacteria,1TRKX@1239|Firmicutes,4H9MX@91061|Bacilli,277WD@186823|Alicyclobacillaceae 91061|Bacilli E The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C SJTD3_k127_6047134_0 1265313.HRUBRA_02716 3.152e-86 311.0 COG3387@1|root,COG3387@2|Bacteria,1MW9J@1224|Proteobacteria,1T2G2@1236|Gammaproteobacteria 1236|Gammaproteobacteria G Glycogen debranching enzyme - - - - - - - - - - - - F5_F8_type_C,GDE_C SJTD3_k127_6048909_0 266117.Rxyl_0932 1.688e-46 185.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity MA20_42315 - - - - - - - - - - - PMT_2 SJTD3_k127_6048909_1 1382304.JNIL01000001_gene2240 2.19e-23 102.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli,277VE@186823|Alicyclobacillaceae 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc SJTD3_k127_6049760_1 1307761.L21SP2_1483 5.708e-86 293.0 COG3638@1|root,COG3638@2|Bacteria,2J6UW@203691|Spirochaetes 203691|Spirochaetes P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system phnC - 3.6.3.28 ko:K02041 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.9 - - ABC_tran SJTD3_k127_6049760_2 1131269.AQVV01000005_gene388 1.83e-80 286.0 COG3639@1|root,COG3639@2|Bacteria 2|Bacteria P organic phosphonate transmembrane transporter activity phnE - - ko:K02042 ko02010,map02010 M00223 - - ko00000,ko00001,ko00002,ko02000 3.A.1.9 - - BPD_transp_1 SJTD3_k127_6049760_4 255470.cbdbA377 2.164e-39 162.0 COG1235@1|root,COG1235@2|Bacteria,2GBG8@200795|Chloroflexi,34CTS@301297|Dehalococcoidia 301297|Dehalococcoidia S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B_2 SJTD3_k127_6049760_0 1254432.SCE1572_02095 3.06e-96 321.0 COG1226@1|root,COG1226@2|Bacteria,1MV0T@1224|Proteobacteria,43DUN@68525|delta/epsilon subdivisions,2WYXG@28221|Deltaproteobacteria,2Z0V5@29|Myxococcales 28221|Deltaproteobacteria P Castor and Pollux, part of voltage-gated ion channel - - - - - - - - - - - - Castor_Poll_mid SJTD3_k127_6050042_2 525904.Tter_0619 9.727e-72 251.0 COG1063@1|root,COG1063@2|Bacteria,2NR1G@2323|unclassified Bacteria 2|Bacteria E Glucose dehydrogenase C-terminus gutB - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N,Glu_dehyd_C SJTD3_k127_6050042_0 525904.Tter_0620 5.649e-142 464.0 COG2006@1|root,COG2006@2|Bacteria 2|Bacteria U 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - - - - - - - - - - DUF2088,DUF362 SJTD3_k127_6050042_1 1033734.CAET01000006_gene3901 1.712e-72 248.0 COG0269@1|root,COG0269@2|Bacteria,1TQ55@1239|Firmicutes,4HBMT@91061|Bacilli,1ZBDI@1386|Bacillus 91061|Bacilli G 3-hexulose-6-phosphate synthase hxlA GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.2.43 ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 M00345,M00580 R05338 RC00421,RC00422 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase SJTD3_k127_6055609_0 136993.KB900626_gene1314 1.577e-30 126.0 COG2062@1|root,COG2062@2|Bacteria,1N0FX@1224|Proteobacteria,2UBYD@28211|Alphaproteobacteria,36YMG@31993|Methylocystaceae 28211|Alphaproteobacteria T Phosphoglycerate mutase family sixA - - ko:K08296 - - - - ko00000,ko01000 - - - His_Phos_1 SJTD3_k127_6055609_3 684949.ATTJ01000001_gene799 7.928e-13 76.0 2EAFX@1|root,334J9@2|Bacteria,1WMVW@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus - - - - - - - - - - - - - - - SJTD3_k127_6055609_4 1285586.H131_14853 3.298e-12 80.0 COG1404@1|root,COG1404@2|Bacteria 2|Bacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - Peptidase_M8,Peptidase_S8,SLH SJTD3_k127_6055609_1 640511.BC1002_6488 9.758e-18 98.0 COG1520@1|root,COG1520@2|Bacteria,1PIDA@1224|Proteobacteria,2W71D@28216|Betaproteobacteria,1K61Z@119060|Burkholderiaceae 28216|Betaproteobacteria S PQQ-like domain - - - - - - - - - - - - PQQ_2 SJTD3_k127_6055609_2 1121877.JQKF01000022_gene2300 3.117e-16 81.0 COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4CNBN@84992|Acidimicrobiia 84992|Acidimicrobiia J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p SJTD3_k127_60570_2 525904.Tter_2228 5.993e-106 348.0 COG2017@1|root,COG2017@2|Bacteria,2NQQX@2323|unclassified Bacteria 2|Bacteria G Domain of unknown function (DUF4432) - - - - - - - - - - - - DUF4432 SJTD3_k127_60570_0 525904.Tter_0163 1.57e-146 480.0 COG0075@1|root,COG0075@2|Bacteria,2NP31@2323|unclassified Bacteria 2|Bacteria E Aminotransferase class-V spt - 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 M00346,M00532 R00369,R00372,R00585,R00588,R10908 RC00006,RC00008,RC00018,RC03305 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 SJTD3_k127_60570_1 525904.Tter_0340 1.06e-108 353.0 COG0605@1|root,COG0605@2|Bacteria,2NP62@2323|unclassified Bacteria 2|Bacteria P Destroys radicals which are normally produced within the cells and which are toxic to biological systems sodA - 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N SJTD3_k127_6078910_3 479434.Sthe_0933 4.905e-23 107.0 COG1807@1|root,COG1807@2|Bacteria,2G8YZ@200795|Chloroflexi 200795|Chloroflexi M Membrane - - - - - - - - - - - - - SJTD3_k127_6078910_0 246194.CHY_0125 8.126e-240 753.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,42F21@68295|Thermoanaerobacterales 186801|Clostridia F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS01075 CTP_synth_N,GATase SJTD3_k127_6078910_1 525904.Tter_0072 5.495e-70 243.0 COG2220@1|root,COG2220@2|Bacteria,2NR9T@2323|unclassified Bacteria 2|Bacteria S Beta-lactamase superfamily domain - - - - - - - - - - - - Lactamase_B_3 SJTD3_k127_6078910_4 1329250.WOSG25_200130 1.081e-05 57.0 COG3942@1|root,COG3942@2|Bacteria,1VCXB@1239|Firmicutes,4HMCB@91061|Bacilli,4AYUJ@81850|Leuconostocaceae 91061|Bacilli S surface antigen p40 - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP SJTD3_k127_6078910_2 485913.Krac_9072 3.028e-57 205.0 COG3214@1|root,COG3214@2|Bacteria,2G766@200795|Chloroflexi 200795|Chloroflexi S Winged helix DNA-binding domain - - - - - - - - - - - - HTH_42 SJTD3_k127_6099448_0 525904.Tter_0027 2.613e-67 232.0 COG0821@1|root,COG0821@2|Bacteria,2NNPV@2323|unclassified Bacteria 2|Bacteria I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate ispG GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R08689,R10859 RC01486 ko00000,ko00001,ko00002,ko01000 - - iAF1260.b2515,iAPECO1_1312.APECO1_4009,iB21_1397.B21_02369,iBWG_1329.BWG_2279,iE2348C_1286.E2348C_2798,iEC55989_1330.EC55989_2800,iECABU_c1320.ECABU_c28200,iECBD_1354.ECBD_1171,iECB_1328.ECB_02407,iECDH10B_1368.ECDH10B_2681,iECDH1ME8569_1439.ECDH1ME8569_2442,iECDH1ME8569_1439.EcDH1_1153,iECD_1391.ECD_02407,iECED1_1282.ECED1_2946,iECH74115_1262.ECH74115_3740,iECIAI39_1322.ECIAI39_2716,iECNA114_1301.ECNA114_2593,iECO103_1326.ECO103_3032,iECO111_1330.ECO111_3239,iECO26_1355.ECO26_3562,iECOK1_1307.ECOK1_2863,iECP_1309.ECP_2520,iECS88_1305.ECS88_2691,iECSE_1348.ECSE_2801,iECSF_1327.ECSF_2359,iECSP_1301.ECSP_3455,iECW_1372.ECW_m2740,iECs_1301.ECs3377,iEKO11_1354.EKO11_1218,iETEC_1333.ETEC_2672,iEcDH1_1363.EcDH1_1153,iEcE24377_1341.EcE24377A_2799,iEcolC_1368.EcolC_1162,iHN637.CLJU_RS06430,iIT341.HP0625,iJN678.gcpE,iJO1366.b2515,iJR904.b2515,iLF82_1304.LF82_1130,iNRG857_1313.NRG857_12515,iUMN146_1321.UM146_04130,iUMNK88_1353.UMNK88_3165,iUTI89_1310.UTI89_C2836,iWFL_1372.ECW_m2740,iY75_1357.Y75_RS13130,iYL1228.KPN_02845,iZ_1308.Z3778,ic_1306.c3037 GcpE SJTD3_k127_6099448_1 1219375.CM002139_gene74 7.856e-16 90.0 COG1520@1|root,COG1520@2|Bacteria,1QU2U@1224|Proteobacteria,1S1NX@1236|Gammaproteobacteria,1X7G8@135614|Xanthomonadales 135614|Xanthomonadales S dehydrogenase - - 1.1.2.6 ko:K05889 - - R03136 - ko00000,ko01000 - - - PQQ,PQQ_2,PQQ_3 SJTD3_k127_6118299_1 479434.Sthe_1779 2.882e-18 90.0 COG1807@1|root,COG1807@2|Bacteria,2GBE9@200795|Chloroflexi,27Z44@189775|Thermomicrobia 189775|Thermomicrobia M Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723 SJTD3_k127_6118299_0 485913.Krac_6791 3.659e-19 90.0 COG2261@1|root,COG2261@2|Bacteria,2G9IB@200795|Chloroflexi 200795|Chloroflexi S PFAM Transglycosylase-associated protein - - - - - - - - - - - - Transgly_assoc SJTD3_k127_6118299_2 1382356.JQMP01000003_gene1753 2.351e-11 68.0 COG2261@1|root,COG2261@2|Bacteria,2GA9T@200795|Chloroflexi,27ZAS@189775|Thermomicrobia 189775|Thermomicrobia S transglycosylase associated protein - - - - - - - - - - - - - SJTD3_k127_6139658_3 697281.Mahau_2655 1.042e-61 218.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,42EU5@68295|Thermoanaerobacterales 186801|Clostridia J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 SJTD3_k127_6139658_2 266117.Rxyl_2122 4.434e-65 231.0 COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4CQMJ@84995|Rubrobacteria 84995|Rubrobacteria S O-methyltransferase family 3 - - - - - - - - - - - - Methyltransf_3 SJTD3_k127_6139658_5 1382304.JNIL01000001_gene2639 4.02e-42 162.0 COG0454@1|root,COG0456@2|Bacteria,1VJPU@1239|Firmicutes,4HXYC@91061|Bacilli,27AFB@186823|Alicyclobacillaceae 91061|Bacilli K FR47-like protein - - - - - - - - - - - - FR47 SJTD3_k127_6139658_0 479434.Sthe_1784 9.631e-122 396.0 COG0074@1|root,COG0074@2|Bacteria,2G5R4@200795|Chloroflexi,27XS4@189775|Thermomicrobia 189775|Thermomicrobia C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit sucD - 6.2.1.5 ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00173,M00374,M00620 R00405,R02404 RC00004,RC00014 ko00000,ko00001,ko00002,ko01000 - - - CoA_binding,Ligase_CoA SJTD3_k127_6139658_1 479434.Sthe_3084 1.918e-72 266.0 COG4149@1|root,COG4149@2|Bacteria,2G6FA@200795|Chloroflexi,27YA5@189775|Thermomicrobia 189775|Thermomicrobia P Binding-protein-dependent transport system inner membrane component - - - ko:K02018 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - BPD_transp_1 SJTD3_k127_6139658_4 1128421.JAGA01000002_gene1244 2.29e-57 213.0 COG0725@1|root,COG0725@2|Bacteria,2NQT8@2323|unclassified Bacteria 2|Bacteria P Bacterial extracellular solute-binding protein modA GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - ko:K02020 ko02010,map02010 M00189 - - ko00000,ko00001,ko00002,ko02000 3.A.1.8 - - SBP_bac_11 SJTD3_k127_6139658_6 266117.Rxyl_3207 4e-17 84.0 COG3585@1|root,COG3585@2|Bacteria,2IKQV@201174|Actinobacteria,4CQRP@84995|Rubrobacteria 84995|Rubrobacteria H TOBE domain - - - - - - - - - - - - MerR,TOBE SJTD3_k127_6139658_7 1118054.CAGW01000007_gene3804 1.112e-16 85.0 COG3835@1|root,COG3835@2|Bacteria,1UHNB@1239|Firmicutes,4HFKR@91061|Bacilli,277M4@186822|Paenibacillaceae 91061|Bacilli KT Purine catabolism regulatory protein-like family pucR - - ko:K09684 - - - - ko00000,ko03000 - - - HTH_30,PucR SJTD3_k127_6142018_1 945713.IALB_1869 5.2e-168 550.0 COG1009@1|root,COG1009@2|Bacteria 2|Bacteria CP NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit nuoL - 1.6.5.3 ko:K00341 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Proton_antipo_C,Proton_antipo_M,Proton_antipo_N SJTD3_k127_6142018_11 1382306.JNIM01000001_gene3462 1.087e-23 105.0 COG0713@1|root,COG0713@2|Bacteria,2G6TP@200795|Chloroflexi 200795|Chloroflexi C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 ko:K00340 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q2 SJTD3_k127_6142018_10 479434.Sthe_0297 3.663e-29 128.0 COG0839@1|root,COG0839@2|Bacteria,2G78H@200795|Chloroflexi,27Y64@189775|Thermomicrobia 189775|Thermomicrobia C Belongs to the complex I subunit 6 family - - 1.6.5.3 ko:K00339 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q3 SJTD3_k127_6142018_9 525904.Tter_1536 1.021e-30 130.0 COG1143@1|root,COG1143@2|Bacteria,2NPQR@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoI GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3,1.6.99.3 ko:K00338,ko:K02573,ko:K03941 ko00190,ko01100,ko04714,ko04723,ko04932,ko05010,ko05012,ko05016,map00190,map01100,map04714,map04723,map04932,map05010,map05012,map05016 M00143,M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1,3.D.1.6 - - Fer4,Fer4_7 SJTD3_k127_6142018_4 525904.Tter_1537 1.937e-113 381.0 COG1005@1|root,COG1005@2|Bacteria,2NNTT@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone nuoH - 1.6.5.3 ko:K00337 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iNJ661.Rv3152 NADHdh SJTD3_k127_6142018_2 457570.Nther_0100 3.022e-167 562.0 COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia 186801|Clostridia C Molybdopterin oxidoreductase, Fe4S4 - - 1.17.1.10 ko:K05299 ko00680,ko00720,ko01100,ko01120,ko01200,map00680,map00720,map01100,map01120,map01200 M00377 R00134 RC02796 ko00000,ko00001,ko00002,ko01000 - - - Fer2_4,Fer4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 SJTD3_k127_6142018_0 525904.Tter_1539 1.491e-182 591.0 COG1894@1|root,COG1894@2|Bacteria,2NNM1@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - 1.12.1.3,1.6.5.3 ko:K00335,ko:K18331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - 2Fe-2S_thioredx,Complex1_51K,Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2,SLBB SJTD3_k127_6142018_8 1120985.AUMI01000014_gene1150 6.47e-31 134.0 COG1905@1|root,COG1905@2|Bacteria,1V737@1239|Firmicutes,4H42Q@909932|Negativicutes 909932|Negativicutes C Thioredoxin-like [2Fe-2S] ferredoxin - - - - - - - - - - - - 2Fe-2S_thioredx SJTD3_k127_6142018_3 479434.Sthe_0295 2.722e-149 484.0 COG0649@1|root,COG0649@2|Bacteria,2G5MM@200795|Chloroflexi,27XG6@189775|Thermomicrobia 189775|Thermomicrobia C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoD - 1.6.5.3 ko:K00333 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Complex1_49kDa SJTD3_k127_6142018_7 525904.Tter_1542 2.978e-52 190.0 COG0852@1|root,COG0852@2|Bacteria,2NPN6@2323|unclassified Bacteria 2|Bacteria C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoC GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 ko:K00332 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - iAF987.Gmet_3353 Complex1_30kDa SJTD3_k127_6142018_6 479434.Sthe_0293 4.407e-63 222.0 COG0377@1|root,COG0377@2|Bacteria,2G6BJ@200795|Chloroflexi,27XWB@189775|Thermomicrobia 189775|Thermomicrobia C NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient nuoB - 1.6.5.3 ko:K00331 ko00190,ko01100,map00190,map01100 M00144 R11945 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.1 - - Oxidored_q6 SJTD3_k127_6142018_5 316274.Haur_3369 2.646e-106 356.0 COG0463@1|root,COG0463@2|Bacteria,2GA7J@200795|Chloroflexi 200795|Chloroflexi M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_6142126_5 309799.DICTH_0498 8.909e-13 81.0 2DT25@1|root,33IBS@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_6142126_4 1379698.RBG1_1C00001G0060 7.388e-22 100.0 COG1983@1|root,COG1983@2|Bacteria,2NQ85@2323|unclassified Bacteria 2|Bacteria KT PspC domain pspC - - ko:K03973 - - - - ko00000,ko02048,ko03000 - - - PspC SJTD3_k127_6142126_2 926550.CLDAP_21020 1.44e-61 218.0 COG2197@1|root,COG2197@2|Bacteria,2G8EU@200795|Chloroflexi 200795|Chloroflexi K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg SJTD3_k127_6142126_0 926550.CLDAP_21010 3.474e-91 315.0 COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2G6ZM@200795|Chloroflexi 200795|Chloroflexi T Histidine kinase - - - - - - - - - - - - GAF_2,HATPase_c,HisKA_3 SJTD3_k127_6142126_1 357808.RoseRS_2107 2.668e-68 246.0 COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia 32061|Chloroflexia T Belongs to the universal stress protein A family - - - - - - - - - - - - Usp SJTD3_k127_6142126_7 1121413.JMKT01000009_gene1935 3.122e-06 55.0 2DNS2@1|root,32YVY@2|Bacteria,1N9QQ@1224|Proteobacteria,42X5E@68525|delta/epsilon subdivisions,2X2FX@28221|Deltaproteobacteria,2MDGG@213115|Desulfovibrionales 28221|Deltaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_6149833_1 485913.Krac_2150 1.976e-99 331.0 COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi 2|Bacteria C PFAM Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_6149833_0 927677.ALVU02000004_gene4738 1.348e-123 430.0 COG3903@1|root,COG3903@2|Bacteria 2|Bacteria K ADP binding - - - - - - - - - - - - AAA_22,DUF4062,NB-ARC,TPR_12 SJTD3_k127_6157393_0 1382306.JNIM01000001_gene770 9.006e-81 276.0 COG0036@1|root,COG0036@2|Bacteria,2G6EU@200795|Chloroflexi 200795|Chloroflexi G Belongs to the ribulose-phosphate 3-epimerase family rpe - 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim SJTD3_k127_6157393_1 525904.Tter_0412 1.087e-61 221.0 COG0363@1|root,COG0363@2|Bacteria,2NPBM@2323|unclassified Bacteria 2|Bacteria G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase pgl - 3.1.1.31,3.5.99.6 ko:K01057,ko:K02564 ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200 M00004,M00006,M00008 R00765,R02035 RC00163,RC00537 ko00000,ko00001,ko00002,ko01000 - - - Glucosamine_iso SJTD3_k127_6179175_1 525904.Tter_0032 4.809e-50 184.0 COG0531@1|root,COG0531@2|Bacteria,2NNZQ@2323|unclassified Bacteria 2|Bacteria E Amino acid permease - - - - - - - - - - - - AA_permease_2 SJTD3_k127_6179175_0 926569.ANT_08060 1.33e-101 341.0 COG0449@1|root,COG0449@2|Bacteria,2G5V6@200795|Chloroflexi 200795|Chloroflexi M PFAM sugar isomerase (SIS) - - 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - - SIS SJTD3_k127_618454_1 521011.Mpal_0755 2.118e-17 87.0 COG3391@1|root,arCOG03563@2157|Archaea 2157|Archaea P NHL repeat containing protein - - - - - - - - - - - - CBM_6,HemolysinCabind,NHL,PKD SJTD3_k127_618454_0 317936.Nos7107_2106 1.264e-81 281.0 COG1408@1|root,COG1408@2|Bacteria,1G286@1117|Cyanobacteria,1HK62@1161|Nostocales 1117|Cyanobacteria S PFAM Calcineurin-like phosphoesterase - - - ko:K07098 - - - - ko00000 - - - Metallophos SJTD3_k127_6185003_0 402777.KB235903_gene854 1.411e-93 323.0 COG0683@1|root,COG0683@2|Bacteria,1G16P@1117|Cyanobacteria,1H80W@1150|Oscillatoriales 1117|Cyanobacteria E Receptor family ligand binding region natB - - ko:K01999,ko:K11954 ko02010,ko02024,map02010,map02024 M00237,M00322 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4,3.A.1.4.2,3.A.1.4.6 - - ANF_receptor,Peripla_BP_6 SJTD3_k127_6185003_1 106370.Francci3_2424 3.905e-38 165.0 COG0515@1|root,COG3118@1|root,COG0515@2|Bacteria,COG3118@2|Bacteria,2GJ24@201174|Actinobacteria 201174|Actinobacteria KLT serine threonine protein kinase pknG GO:0001898,GO:0001899,GO:0002682,GO:0002684,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006468,GO:0006520,GO:0006536,GO:0006538,GO:0006541,GO:0006543,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0019752,GO:0030100,GO:0031341,GO:0031342,GO:0031347,GO:0031349,GO:0032879,GO:0035821,GO:0036211,GO:0040007,GO:0042268,GO:0042802,GO:0043170,GO:0043207,GO:0043412,GO:0043436,GO:0043648,GO:0043649,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044403,GO:0044413,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0045918,GO:0046395,GO:0046777,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050764,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0051709,GO:0051710,GO:0051711,GO:0051713,GO:0051802,GO:0051803,GO:0051817,GO:0051832,GO:0052027,GO:0052031,GO:0052164,GO:0052173,GO:0052190,GO:0052200,GO:0052231,GO:0052250,GO:0052255,GO:0052303,GO:0052348,GO:0052369,GO:0052509,GO:0052510,GO:0052550,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052567,GO:0052572,GO:0060627,GO:0065007,GO:0071704,GO:0071944,GO:0075136,GO:0080134,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.11.1 ko:K14949 ko05152,map05152 - - - ko00000,ko00001,ko01000,ko01001 - - - Pkinase,PknG_TPR,PknG_rubred SJTD3_k127_6185003_2 485913.Krac_1758 1.908e-36 154.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA,VWA_2,VWA_3 SJTD3_k127_6185003_3 1499967.BAYZ01000076_gene801 1.018e-05 56.0 2C0BN@1|root,2ZFYM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_6203807_4 525904.Tter_2371 5.088e-34 134.0 COG0642@1|root,COG2202@1|root,COG2203@1|root,COG3290@1|root,COG2202@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,COG3290@2|Bacteria,2NQT3@2323|unclassified Bacteria 2|Bacteria T SMART ATP-binding region ATPase domain protein - - - - - - - - - - - - CBS,CHASE,GAF,GAF_2,HATPase_c,HisKA,PAS,PAS_3,PAS_4,PAS_9,Response_reg SJTD3_k127_6203807_0 251229.Chro_2356 2.204e-117 385.0 COG2326@1|root,COG2326@2|Bacteria,1G159@1117|Cyanobacteria,3VMQS@52604|Pleurocapsales 1117|Cyanobacteria S Polyphosphate kinase 2 (PPK2) - - - - - - - - - - - - PPK2 SJTD3_k127_6203807_2 1173026.Glo7428_2825 2.844e-40 154.0 COG0614@1|root,COG0614@2|Bacteria,1G73G@1117|Cyanobacteria 1117|Cyanobacteria P PD-(D/E)XK nuclease superfamily - - - - - - - - - - - - PDDEXK_3 SJTD3_k127_6203807_6 449447.MAE_32560 7.149e-15 81.0 COG2402@1|root,COG2402@2|Bacteria,1G8EG@1117|Cyanobacteria 1117|Cyanobacteria S Toxic component of a toxin-antitoxin (TA) module. An RNase - - - - - - - - - - - - - SJTD3_k127_6203807_3 671143.DAMO_1226 1.908e-37 145.0 COG0314@1|root,COG0314@2|Bacteria,2NR4E@2323|unclassified Bacteria 2|Bacteria H MoaE protein moaE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE,ThiS SJTD3_k127_6203807_5 765420.OSCT_3166 6.999e-15 78.0 COG0314@1|root,COG1977@1|root,COG0314@2|Bacteria,COG1977@2|Bacteria,2G6YQ@200795|Chloroflexi,376I2@32061|Chloroflexia 32061|Chloroflexia H PFAM molybdopterin biosynthesis MoaE protein moaD - 2.8.1.12 ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 - R09395 RC02507 ko00000,ko00001,ko01000 - - - MoaE,ThiS SJTD3_k127_6203807_1 479434.Sthe_0413 3.094e-62 232.0 COG0477@1|root,COG2814@2|Bacteria,2G8SG@200795|Chloroflexi,27XS0@189775|Thermomicrobia 189775|Thermomicrobia EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 SJTD3_k127_6218317_2 309801.trd_1960 2.857e-27 111.0 COG1376@1|root,COG5479@1|root,COG1376@2|Bacteria,COG5479@2|Bacteria,2G6ZY@200795|Chloroflexi,27XVB@189775|Thermomicrobia 189775|Thermomicrobia M L,D-transpeptidase catalytic domain - - - - - - - - - - - - YkuD SJTD3_k127_6218317_1 1382306.JNIM01000001_gene400 2.068e-46 185.0 COG0457@1|root,COG1396@1|root,COG0457@2|Bacteria,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - - - - - - - - - - HTH_3 SJTD3_k127_6218317_0 479434.Sthe_1693 2.931e-114 394.0 COG3693@1|root,COG5479@1|root,COG3693@2|Bacteria,COG5479@2|Bacteria,2GBGU@200795|Chloroflexi,27Y52@189775|Thermomicrobia 200795|Chloroflexi M Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase SJTD3_k127_6218317_3 1128421.JAGA01000002_gene163 9.85e-25 104.0 COG1063@1|root,COG1063@2|Bacteria,2NPK3@2323|unclassified Bacteria 2|Bacteria E Zinc-binding dehydrogenase tdh - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N SJTD3_k127_6221538_8 153721.MYP_2870 3.324e-05 58.0 COG2133@1|root,COG3209@1|root,COG3250@1|root,COG3291@1|root,COG4447@1|root,COG2133@2|Bacteria,COG3209@2|Bacteria,COG3250@2|Bacteria,COG3291@2|Bacteria,COG4447@2|Bacteria,4NQ3X@976|Bacteroidetes,47SEZ@768503|Cytophagia 976|Bacteroidetes G Legume lectin domain - - - - - - - - - - - - CHU_C,Lectin_legB,PKD SJTD3_k127_6221538_6 357808.RoseRS_0242 3.182e-18 101.0 COG3391@1|root,COG4745@1|root,COG3391@2|Bacteria,COG4745@2|Bacteria,2G5PE@200795|Chloroflexi,3757B@32061|Chloroflexia 32061|Chloroflexia O PFAM NHL repeat containing protein - - - - - - - - - - - - NHL,PMT_2 SJTD3_k127_6221538_1 335543.Sfum_2243 4.758e-84 287.0 COG1216@1|root,COG1216@2|Bacteria,1R50T@1224|Proteobacteria,42P74@68525|delta/epsilon subdivisions,2WK88@28221|Deltaproteobacteria,2MQ8C@213462|Syntrophobacterales 28221|Deltaproteobacteria S Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,Methyltransf_23 SJTD3_k127_6221538_4 1521187.JPIM01000047_gene134 1.308e-58 220.0 COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia 32061|Chloroflexia S PFAM conserved - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SJTD3_k127_6221538_3 479434.Sthe_2017 2.849e-80 276.0 COG1968@1|root,COG1968@2|Bacteria,2G6F7@200795|Chloroflexi,27Y0J@189775|Thermomicrobia 189775|Thermomicrobia V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA SJTD3_k127_6221538_5 525904.Tter_1647 8.43e-33 134.0 COG1399@1|root,COG1399@2|Bacteria,2NQ7G@2323|unclassified Bacteria 2|Bacteria S Uncharacterized ACR, COG1399 yceD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - ko:K07040 - - - - ko00000 - - - DUF177 SJTD3_k127_6221538_7 485913.Krac_8243 2.864e-17 83.0 COG0333@1|root,COG0333@2|Bacteria,2G7EA@200795|Chloroflexi 200795|Chloroflexi J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p SJTD3_k127_6221538_0 1128421.JAGA01000002_gene1728 2.239e-119 394.0 COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria 2|Bacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C SJTD3_k127_6221538_2 326427.Cagg_2986 5.664e-82 283.0 COG0331@1|root,COG0331@2|Bacteria,2G61W@200795|Chloroflexi,375EH@32061|Chloroflexia 32061|Chloroflexia I TIGRFAM malonyl CoA-acyl carrier protein transacylase - - 2.3.1.39 ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyl_transf_1 SJTD3_k127_624336_3 1121468.AUBR01000008_gene2060 6.384e-29 124.0 COG5495@1|root,COG5495@2|Bacteria,1UZZU@1239|Firmicutes,249YF@186801|Clostridia,42G5H@68295|Thermoanaerobacterales 186801|Clostridia S NADP oxidoreductase coenzyme F420-dependent - - - - - - - - - - - - DUF2520,F420_oxidored,Rossmann-like SJTD3_k127_624336_0 357808.RoseRS_1914 3.132e-59 217.0 COG0596@1|root,COG0596@2|Bacteria,2G7BF@200795|Chloroflexi,376W2@32061|Chloroflexia 32061|Chloroflexia S PFAM alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_624336_1 1536770.R50345_29840 1.798e-48 189.0 COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,4HC8Q@91061|Bacilli,26V0V@186822|Paenibacillaceae 91061|Bacilli S Calcineurin-like phosphoesterase superfamily domain ykuE - - ko:K07098 - - - - ko00000 - - - Metallophos,Metallophos_2 SJTD3_k127_624336_2 1536769.P40081_08400 7.691e-30 126.0 COG0154@1|root,COG0726@1|root,COG0154@2|Bacteria,COG0726@2|Bacteria,1TRFI@1239|Firmicutes,4IPR7@91061|Bacilli,26QQV@186822|Paenibacillaceae 91061|Bacilli GJ Amidase - - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase,SLH SJTD3_k127_6244578_0 926550.CLDAP_02300 3.789e-70 261.0 COG5617@1|root,COG5617@2|Bacteria,2G8CQ@200795|Chloroflexi 200795|Chloroflexi S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - SJTD3_k127_6244578_1 383372.Rcas_3538 7.746e-48 190.0 COG0628@1|root,COG0628@2|Bacteria 2|Bacteria D permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - - - - - - - - - - AI-2E_transport SJTD3_k127_6257939_1 500153.JOEK01000017_gene3320 3.781e-10 69.0 COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria 201174|Actinobacteria K Transcriptional regulator - - - - - - - - - - - - AAA_22,BTAD,TPR_12,Trans_reg_C SJTD3_k127_6257939_0 1047013.AQSP01000094_gene17 4.009e-67 235.0 COG1397@1|root,COG1397@2|Bacteria,2NPWB@2323|unclassified Bacteria 2|Bacteria O ADP-ribosylglycohydrolase draG - 3.2.2.24 ko:K05521 - - - - ko00000,ko01000 - - - ADP_ribosyl_GH SJTD3_k127_6259027_2 485913.Krac_11807 3.698e-32 128.0 COG0205@1|root,COG0205@2|Bacteria,2G5XX@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis - - 2.7.1.11,2.7.1.90 ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 - R00756,R00764,R02073,R03236,R04779 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PFK SJTD3_k127_6259027_3 489825.LYNGBM3L_13290 0.0001548 46.0 COG0675@1|root,COG0675@2|Bacteria,1G01E@1117|Cyanobacteria,1H7AA@1150|Oscillatoriales 1117|Cyanobacteria L COG0675 Transposase and inactivated derivatives - - - ko:K07496 - - - - ko00000 - - - HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon SJTD3_k127_6259027_1 326427.Cagg_1685 6.11e-87 299.0 COG1609@1|root,COG1609@2|Bacteria,2G6DT@200795|Chloroflexi,376ZH@32061|Chloroflexia 32061|Chloroflexia K periplasmic binding protein LacI transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 SJTD3_k127_6259027_0 390989.JOEG01000035_gene1749 2.334e-100 340.0 COG0747@1|root,COG0747@2|Bacteria,2I9MB@201174|Actinobacteria,4DI57@85008|Micromonosporales 201174|Actinobacteria E Bacterial extracellular solute-binding proteins, family 5 Middle - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SJTD3_k127_6274262_2 383372.Rcas_1503 7.163e-27 117.0 COG0642@1|root,COG5000@1|root,COG2205@2|Bacteria,COG5000@2|Bacteria,2GBIC@200795|Chloroflexi,3780I@32061|Chloroflexia 32061|Chloroflexia T histidine kinase A domain protein - - 2.7.13.3 ko:K02484 - - - - ko00000,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA SJTD3_k127_6274262_0 765420.OSCT_0550 7.289e-89 298.0 COG0745@1|root,COG0745@2|Bacteria,2GBT3@200795|Chloroflexi,376HQ@32061|Chloroflexia 32061|Chloroflexia K Two component transcriptional regulator, winged helix family - - - ko:K07658 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SJTD3_k127_6274262_3 326427.Cagg_0394 1.106e-06 60.0 29X4F@1|root,30ITB@2|Bacteria,2GB3S@200795|Chloroflexi,377V4@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_6274262_1 1206725.BAFU01000048_gene1214 3.354e-34 137.0 COG0262@1|root,COG4978@1|root,COG0262@2|Bacteria,COG4978@2|Bacteria,2GPXM@201174|Actinobacteria,4G01C@85025|Nocardiaceae 201174|Actinobacteria H RibD C-terminal domain - - - - - - - - - - - - RibD_C SJTD3_k127_6275307_0 469371.Tbis_1757 1.154e-199 642.0 COG0507@1|root,COG0507@2|Bacteria,2GJRK@201174|Actinobacteria,4DXGE@85010|Pseudonocardiales 201174|Actinobacteria L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 SJTD3_k127_6284330_1 479434.Sthe_2141 5.925e-14 72.0 COG2197@1|root,COG3899@1|root,COG2197@2|Bacteria,COG3899@2|Bacteria,2GBNC@200795|Chloroflexi 200795|Chloroflexi K AAA ATPase domain - - - - - - - - - - - - AAA_16 SJTD3_k127_6284330_0 1128421.JAGA01000002_gene435 4.994e-95 329.0 COG2340@1|root,COG3103@1|root,COG2340@2|Bacteria,COG4991@2|Bacteria,2NQ03@2323|unclassified Bacteria 2|Bacteria T sh3 domain protein - - - ko:K07282 - - - - ko00000 - - - CAP,Glyco_hydro_99,SH3_3,SH3_4 SJTD3_k127_6300877_1 316274.Haur_4784 7.209e-39 151.0 COG0412@1|root,COG0412@2|Bacteria,2G8GH@200795|Chloroflexi 200795|Chloroflexi Q Alpha/beta hydrolase family - - - - - - - - - - - - - SJTD3_k127_6300877_0 485913.Krac_3491 5.17e-110 365.0 COG2141@1|root,COG2141@2|Bacteria,2G6CZ@200795|Chloroflexi 2|Bacteria C COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_6300877_2 1041139.KB902646_gene3375 1.628e-37 145.0 2EBN3@1|root,335NA@2|Bacteria,1PS1W@1224|Proteobacteria,2V490@28211|Alphaproteobacteria,4BFSU@82115|Rhizobiaceae 28211|Alphaproteobacteria S Domain of unknown function (DUF4440) - - - - - - - - - - - - DUF4440 SJTD3_k127_6300877_3 485913.Krac_5179 1.547e-13 70.0 COG2355@1|root,COG2355@2|Bacteria,2G5Y0@200795|Chloroflexi 200795|Chloroflexi E PFAM peptidase M19 renal dipeptidase - - 3.4.13.19 ko:K01273 - - - - ko00000,ko00537,ko01000,ko01002,ko04147 - - - Peptidase_M19 SJTD3_k127_6302910_0 1128421.JAGA01000002_gene1856 5.144e-180 578.0 COG1132@1|root,COG1132@2|Bacteria,2NNVD@2323|unclassified Bacteria 2|Bacteria V ABC transporter MdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SJTD3_k127_6304864_3 1382356.JQMP01000003_gene1603 4.264e-40 151.0 COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi,27Z4D@189775|Thermomicrobia 189775|Thermomicrobia S DoxX - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX SJTD3_k127_6304864_1 479434.Sthe_2605 4.997e-67 236.0 COG2259@1|root,COG2259@2|Bacteria,2G6TC@200795|Chloroflexi,27Z4D@189775|Thermomicrobia 189775|Thermomicrobia S DoxX - - 1.8.5.2 ko:K16937 ko00920,ko01120,map00920,map01120 - R07177 - ko00000,ko00001,ko01000 3.D.4.9 - - DoxX SJTD3_k127_6304864_0 42256.RradSPS_2794 5.382e-134 446.0 COG0446@1|root,COG0446@2|Bacteria,2HQQT@201174|Actinobacteria,4CSDR@84995|Rubrobacteria 84995|Rubrobacteria S Pyridine nucleotide-disulphide oxidoreductase - - 1.8.5.4 ko:K17218 ko00920,map00920 - R10152 RC03155 ko00000,ko00001,ko01000 - - - Pyr_redox_2 SJTD3_k127_6304864_2 1123320.KB889686_gene587 6.325e-61 216.0 COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria 201174|Actinobacteria H Dihydrofolate reductase - - - - - - - - - - - - RibD_C SJTD3_k127_6309555_1 1122927.KB895425_gene467 3.647e-64 226.0 COG2267@1|root,COG2267@2|Bacteria,1UNHU@1239|Firmicutes,4IUES@91061|Bacilli,277K5@186822|Paenibacillaceae 91061|Bacilli I Serine aminopeptidase, S33 - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_6309555_0 1268072.PSAB_08730 3.891e-67 238.0 2AKFW@1|root,31B7M@2|Bacteria,1TZN5@1239|Firmicutes,4I8X9@91061|Bacilli,270NP@186822|Paenibacillaceae 91061|Bacilli S Protein of unknown function (DUF998) - - - - - - - - - - - - DUF998 SJTD3_k127_6309555_2 1268072.PSAB_19235 3.202e-18 86.0 COG0202@1|root,COG0202@2|Bacteria,1UM11@1239|Firmicutes 1239|Firmicutes K Bacterial RNA polymerase, alpha chain C terminal domain - - - - - - - - - - - - RNA_pol_A_CTD SJTD3_k127_6319352_0 479434.Sthe_2950 8.447e-210 666.0 COG1350@1|root,COG1350@2|Bacteria,2G5YY@200795|Chloroflexi,27XSD@189775|Thermomicrobia 189775|Thermomicrobia E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine - - 4.2.1.20 ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - PALP SJTD3_k127_6321437_0 335541.Swol_1787 1.742e-159 518.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,42KH2@68298|Syntrophomonadaceae 186801|Clostridia H Glutamine synthetase, catalytic domain - - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N SJTD3_k127_6327435_1 379066.GAU_2499 9.123e-49 187.0 COG0404@1|root,COG0404@2|Bacteria,1ZTBZ@142182|Gemmatimonadetes 142182|Gemmatimonadetes H The glycine cleavage system catalyzes the degradation of glycine gcvT - 2.1.2.10 ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 M00532 R01221,R02300,R04125 RC00022,RC00069,RC00183,RC02834 ko00000,ko00001,ko00002,ko01000 - - - GCV_T,GCV_T_C SJTD3_k127_6327435_2 479434.Sthe_1432 7.456e-43 166.0 COG2137@1|root,COG2137@2|Bacteria,2G6WA@200795|Chloroflexi,27YM4@189775|Thermomicrobia 189775|Thermomicrobia S RecX family recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX SJTD3_k127_6327435_0 316274.Haur_4194 1.536e-158 507.0 COG0468@1|root,COG0468@2|Bacteria,2G5WE@200795|Chloroflexi,3756R@32061|Chloroflexia 32061|Chloroflexia L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA SJTD3_k127_6344574_2 1170562.Cal6303_1042 4.365e-41 170.0 COG2208@1|root,COG2208@2|Bacteria,1G160@1117|Cyanobacteria,1HMW2@1161|Nostocales 1117|Cyanobacteria KT Stage II sporulation protein E (SpoIIE) - - 3.1.3.3 ko:K07315 - - - - ko00000,ko01000,ko03021 - - - PilJ,SpoIIE SJTD3_k127_6344574_0 926569.ANT_15870 5.982e-95 337.0 COG1287@1|root,COG1287@2|Bacteria 2|Bacteria S oligosaccharyl transferase activity - - 2.4.99.18 ko:K07151 ko00510,ko00513,ko01100,ko04141,map00510,map00513,map01100,map04141 M00072 R04216,R05976 RC00005,RC00482 ko00000,ko00001,ko00002,ko01000,ko01003 - GT66 - PMT_2 SJTD3_k127_6344574_1 765420.OSCT_1153 1.654e-65 234.0 COG0500@1|root,COG2226@2|Bacteria,2GAN1@200795|Chloroflexi,376TH@32061|Chloroflexia 32061|Chloroflexia H Methyltransferase domain - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_6344574_3 357808.RoseRS_1335 9.22e-23 98.0 COG4481@1|root,COG4481@2|Bacteria,2G7GI@200795|Chloroflexi,37629@32061|Chloroflexia 32061|Chloroflexia S Bacterial protein of unknown function (DUF951) - - - - - - - - - - - - DUF951 SJTD3_k127_6344574_4 479434.Sthe_0413 1.597e-15 81.0 COG0477@1|root,COG2814@2|Bacteria,2G8SG@200795|Chloroflexi,27XS0@189775|Thermomicrobia 189775|Thermomicrobia EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_1 SJTD3_k127_6346896_2 78346.BRUM_0901 1.641e-08 62.0 2CBVU@1|root,3324G@2|Bacteria,2IKKE@201174|Actinobacteria,4D106@85004|Bifidobacteriales 201174|Actinobacteria S Domain of unknown function (DUF4418) - - - - - - - - - - - - DUF4418 SJTD3_k127_6346896_0 292459.STH855 1.212e-61 228.0 COG0577@1|root,COG0577@2|Bacteria,1UYZ9@1239|Firmicutes,2484S@186801|Clostridia 186801|Clostridia V Efflux ABC transporter, permease protein - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD SJTD3_k127_6346896_1 713587.THITH_13325 1.888e-60 217.0 COG1136@1|root,COG1136@2|Bacteria,1MVSQ@1224|Proteobacteria,1RMWK@1236|Gammaproteobacteria 1236|Gammaproteobacteria V Part of the ABC transporter complex LolCDE involved in the translocation of - - - ko:K09810 ko02010,map02010 M00255 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.125 - - ABC_tran SJTD3_k127_6346896_3 1449063.JMLS01000016_gene953 4.332e-06 56.0 2EG8N@1|root,33A0G@2|Bacteria,1VMHK@1239|Firmicutes,4HSIH@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - SJTD3_k127_6357500_3 1397528.Q671_14590 1.873e-09 69.0 COG0591@1|root,COG0642@1|root,COG0591@2|Bacteria,COG2205@2|Bacteria,1MUY7@1224|Proteobacteria,1RP2U@1236|Gammaproteobacteria,1XNQM@135619|Oceanospirillales 135619|Oceanospirillales T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA SJTD3_k127_6357500_0 671143.DAMO_1252 3.124e-116 400.0 COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,2NNZ0@2323|unclassified Bacteria 2|Bacteria P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family ybaL GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03455 - - - - ko00000 2.A.37 - - Na_H_Exchanger,TrkA_C,TrkA_N SJTD3_k127_6357500_2 63737.Npun_F1156 2.459e-43 164.0 COG3685@1|root,COG3685@2|Bacteria,1G9WB@1117|Cyanobacteria,1HM80@1161|Nostocales 1117|Cyanobacteria S Domain of unknown function (DUF892) - - - - - - - - - - - - DUF892 SJTD3_k127_6357500_1 479434.Sthe_0772 1.659e-67 241.0 COG4221@1|root,COG4221@2|Bacteria,2G6TQ@200795|Chloroflexi 200795|Chloroflexi S Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short SJTD3_k127_6360549_3 543632.JOJL01000013_gene9452 2.059e-05 58.0 COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4D962@85008|Micromonosporales 201174|Actinobacteria G Fibronectin type III-like domain - - 3.2.1.21 ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 - R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 ko00000,ko00001,ko01000 - GH3 - Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14 SJTD3_k127_6360549_1 1382306.JNIM01000001_gene377 8.805e-59 210.0 COG2185@1|root,COG2185@2|Bacteria,2G6S9@200795|Chloroflexi 200795|Chloroflexi I PFAM cobalamin B12-binding domain protein - - 5.4.99.2 ko:K01849 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00375,M00376,M00741 R00833 RC00395 ko00000,ko00001,ko00002,ko01000 - - - B12-binding SJTD3_k127_6360549_0 342949.PNA2_0789 3.112e-88 302.0 COG1703@1|root,arCOG01226@2157|Archaea,2XUHG@28890|Euryarchaeota,242YC@183968|Thermococci 183968|Thermococci E GTPase activity - - - ko:K07588 - - - - ko00000,ko01000 - - - ArgK SJTD3_k127_6360549_2 926550.CLDAP_25540 4.299e-23 102.0 COG2197@1|root,COG2197@2|Bacteria,2G6PA@200795|Chloroflexi 200795|Chloroflexi K Response regulator receiver - - - - - - - - - - - - GerE,Response_reg SJTD3_k127_6369401_0 479435.Kfla_2275 4.195e-32 129.0 2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4DR0C@85009|Propionibacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_6369401_2 1121028.ARQE01000002_gene1738 1.906e-25 110.0 COG0652@1|root,COG0652@2|Bacteria,1R9ZQ@1224|Proteobacteria,2U5BD@28211|Alphaproteobacteria,2PJVW@255475|Aurantimonadaceae 28211|Alphaproteobacteria M PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K01802,ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase SJTD3_k127_6369401_1 767817.Desgi_3798 6.441e-28 125.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia 186801|Clostridia O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Pro_isomerase SJTD3_k127_6396213_1 324602.Caur_3254 2.739e-78 278.0 COG0392@1|root,COG0392@2|Bacteria,2G6NX@200795|Chloroflexi,3765H@32061|Chloroflexia 32061|Chloroflexia S PFAM conserved - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SJTD3_k127_6396213_0 357808.RoseRS_3583 7.496e-106 356.0 COG0438@1|root,COG0438@2|Bacteria,2G61I@200795|Chloroflexi,3753V@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_6396213_3 324602.Caur_3733 6.972e-22 106.0 COG2244@1|root,COG2244@2|Bacteria,2G6CM@200795|Chloroflexi,375EC@32061|Chloroflexia 32061|Chloroflexia S Polysaccharide biosynthesis protein - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C SJTD3_k127_6398775_1 309801.trd_0205 1.804e-119 397.0 COG1674@1|root,COG1674@2|Bacteria,2G5XC@200795|Chloroflexi,27XSG@189775|Thermomicrobia 189775|Thermomicrobia D Ftsk_gamma - - - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma SJTD3_k127_6398775_0 1440774.Y900_011025 1.237e-184 592.0 COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,238B3@1762|Mycobacteriaceae 201174|Actinobacteria Q Multicopper oxidase - - 1.3.3.5 ko:K04753,ko:K08100 ko00860,ko01110,map00860,map01110 - R02394 RC01983 ko00000,ko00001,ko01000 - - - Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3 SJTD3_k127_6411467_0 525904.Tter_0430 1.143e-171 564.0 COG3250@1|root,COG3250@2|Bacteria,2NPI4@2323|unclassified Bacteria 2|Bacteria G Glycosyl hydrolases family 2, TIM barrel domain - - - - - - - - - - - - Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N SJTD3_k127_6411757_0 1173027.Mic7113_3917 3.309e-27 123.0 COG2124@1|root,COG2124@2|Bacteria,1G28M@1117|Cyanobacteria,1H767@1150|Oscillatoriales 1117|Cyanobacteria C Cytochrome p450 - - - - - - - - - - - - p450 SJTD3_k127_6411757_1 1382356.JQMP01000003_gene1531 1.476e-22 102.0 COG2340@1|root,COG5479@1|root,COG2340@2|Bacteria,COG5479@2|Bacteria,2GBCS@200795|Chloroflexi,27YT2@189775|Thermomicrobia 189775|Thermomicrobia M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP SJTD3_k127_6414071_0 926569.ANT_03500 1.25e-94 318.0 COG0020@1|root,COG0020@2|Bacteria,2G65C@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS - 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf SJTD3_k127_6415472_1 1120973.AQXL01000097_gene902 1.745e-97 331.0 COG3616@1|root,COG3616@2|Bacteria,1TSES@1239|Firmicutes,4HA93@91061|Bacilli,278J8@186823|Alicyclobacillaceae 91061|Bacilli E Putative serine dehydratase domain - - - - - - - - - - - - Ala_racemase_N,D-ser_dehydrat SJTD3_k127_6415472_0 926550.CLDAP_30940 4.126e-199 632.0 COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi 200795|Chloroflexi E Pyridoxal-dependent decarboxylase conserved domain - - 4.1.1.105,4.1.1.28,4.1.2.27 ko:K01593,ko:K01634 ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034 M00037,M00042,M00100 R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516 RC00264,RC00299,RC00721,RC01266 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyridoxal_deC SJTD3_k127_6415472_2 479434.Sthe_1752 1.464e-52 196.0 COG0728@1|root,COG0728@2|Bacteria,2G5PF@200795|Chloroflexi,27Y0W@189775|Thermomicrobia 189775|Thermomicrobia S MviN-like protein - - - ko:K03980 - - - - ko00000,ko01011,ko02000 2.A.66.4 - - MVIN SJTD3_k127_642970_0 237368.SCABRO_03062 3.849e-36 148.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1,Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31 SJTD3_k127_642970_1 768704.Desmer_1347 5.315e-20 103.0 COG2247@1|root,COG3391@1|root,COG2247@2|Bacteria,COG3391@2|Bacteria,1V2E4@1239|Firmicutes,24TKC@186801|Clostridia 186801|Clostridia M NHL repeat - - - - - - - - - - - - NHL SJTD3_k127_6430697_2 889378.Spiaf_0398 1.965e-32 128.0 COG4430@1|root,COG4430@2|Bacteria,2JBBZ@203691|Spirochaetes 203691|Spirochaetes S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA SJTD3_k127_6430697_1 485913.Krac_5138 5.641e-60 213.0 COG0110@1|root,COG0110@2|Bacteria,2G9TX@200795|Chloroflexi 200795|Chloroflexi H Transferase hexapeptide repeat containing protein - - - - - - - - - - - - - SJTD3_k127_6430697_0 316274.Haur_4489 1.751e-129 430.0 COG0438@1|root,COG0438@2|Bacteria,2G67A@200795|Chloroflexi,374TH@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_6432239_0 383372.Rcas_1949 1.206e-89 306.0 COG1216@1|root,COG1216@2|Bacteria,2G5U8@200795|Chloroflexi,374YQ@32061|Chloroflexia 32061|Chloroflexia M PFAM glycosyl transferase family 2 - - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3 SJTD3_k127_6437464_1 1121468.AUBR01000094_gene767 3.262e-33 142.0 COG0526@1|root,COG0526@2|Bacteria,1V7JP@1239|Firmicutes,25ET7@186801|Clostridia,42JE2@68295|Thermoanaerobacterales 186801|Clostridia CO Thioredoxin-like - - - ko:K06196 - - - - ko00000,ko02000 5.A.1.2 - - AhpC-TSA,Redoxin SJTD3_k127_6437464_0 357808.RoseRS_3033 1.549e-146 475.0 COG3214@1|root,COG3214@2|Bacteria,2G82W@200795|Chloroflexi,3771W@32061|Chloroflexia 32061|Chloroflexia S Winged helix DNA-binding domain - - - ko:K09927 - - - - ko00000 - - - HTH_42 SJTD3_k127_6450922_0 215803.DB30_1335 5.936e-73 269.0 COG0596@1|root,COG0596@2|Bacteria,1R6KU@1224|Proteobacteria,438C4@68525|delta/epsilon subdivisions,2WYM4@28221|Deltaproteobacteria,2YWIJ@29|Myxococcales 28221|Deltaproteobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1 SJTD3_k127_6476936_1 525904.Tter_1796 4.326e-69 237.0 COG0777@1|root,COG0777@2|Bacteria,2NP40@2323|unclassified Bacteria 2|Bacteria I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS20740 ACCA,Carboxyl_trans SJTD3_k127_6476936_0 1521187.JPIM01000086_gene731 2.391e-100 344.0 COG0825@1|root,COG0825@2|Bacteria,2G7S3@200795|Chloroflexi,376V0@32061|Chloroflexia 32061|Chloroflexia I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA SJTD3_k127_6476936_3 1499967.BAYZ01000182_gene4427 1.685e-28 120.0 COG5513@1|root,COG5513@2|Bacteria 2|Bacteria G serine-type aminopeptidase activity - - - - - - - - - - - - DUF3298,DUF4163 SJTD3_k127_6476936_2 525904.Tter_1833 4.063e-29 119.0 COG2151@1|root,COG2151@2|Bacteria,2NPUI@2323|unclassified Bacteria 2|Bacteria S Pfam:DUF59 yitW - - ko:K02612 ko00360,ko01120,map00360,map01120 - R09838 RC02690 ko00000,ko00001 - - - FeS_assembly_P SJTD3_k127_6494893_0 324602.Caur_0864 7.033e-108 360.0 COG0863@1|root,COG0863@2|Bacteria,2G650@200795|Chloroflexi,3768C@32061|Chloroflexia 32061|Chloroflexia L Conserved hypothetical protein 95 - - - - - - - - - - - - N6_N4_Mtase SJTD3_k127_6494893_1 880074.BARVI_08660 2.138e-81 286.0 COG3392@1|root,COG3392@2|Bacteria,4NJNW@976|Bacteroidetes,2FRYH@200643|Bacteroidia,22YFJ@171551|Porphyromonadaceae 976|Bacteroidetes L DNA methyltransferase - - 2.1.1.72 ko:K07318 - - - - ko00000,ko01000,ko02048 - - - MethyltransfD12 SJTD3_k127_6494893_2 383372.Rcas_1699 8.48e-76 264.0 COG1091@1|root,COG1091@2|Bacteria,2G6NS@200795|Chloroflexi,375G0@32061|Chloroflexia 32061|Chloroflexia M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose - - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind SJTD3_k127_6494893_3 1128421.JAGA01000002_gene1830 2.397e-30 124.0 COG1216@1|root,COG1216@2|Bacteria,2NPYM@2323|unclassified Bacteria 2|Bacteria L Glycosyltransferase like family 2 wbbL_2 - - ko:K07011 - - - - ko00000 - - - Glycos_transf_2 SJTD3_k127_6500320_1 479434.Sthe_0116 8.098e-61 223.0 COG2146@1|root,COG4244@1|root,COG2146@2|Bacteria,COG4244@2|Bacteria 2|Bacteria E Membrane - - - - - - - - - - - - DUF2231,Rieske SJTD3_k127_6500320_2 1267535.KB906767_gene4012 5.981e-14 78.0 COG3477@1|root,COG3477@2|Bacteria,3Y7QZ@57723|Acidobacteria 57723|Acidobacteria S Protein of unknown function (DUF1440) - - - ko:K08996 - - - - ko00000 - - - DUF1440 SJTD3_k127_6500320_0 357808.RoseRS_0717 1.534e-129 417.0 COG2897@1|root,COG2897@2|Bacteria,2G5XI@200795|Chloroflexi,374RX@32061|Chloroflexia 32061|Chloroflexia P PFAM Rhodanese domain protein - - 2.8.1.1,2.8.1.2 ko:K01011 ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122 - R01931,R03105,R03106 RC00214 ko00000,ko00001,ko01000 - - - Rhodanese SJTD3_k127_6506512_0 1382306.JNIM01000001_gene2853 0.0 1012.0 COG2766@1|root,COG2766@2|Bacteria,2G65T@200795|Chloroflexi 200795|Chloroflexi T PrkA AAA domain protein - - - ko:K07180 - - - - ko00000 - - - AAA_PrkA,PrkA SJTD3_k127_6506512_3 446471.Xcel_2365 8.284e-30 126.0 COG2227@1|root,COG2227@2|Bacteria,2IIE2@201174|Actinobacteria 201174|Actinobacteria H 3-demethylubiquinone-9 3-O-methyltransferase activity - - 2.1.1.11 ko:K03428 ko00860,ko01100,ko01110,map00860,map01100,map01110 - R04237 RC00003,RC00460 ko00000,ko00001,ko01000 - - - Methyltransf_11,Methyltransf_25 SJTD3_k127_6506512_2 1521187.JPIM01000067_gene1065 7.454e-30 125.0 COG0494@1|root,COG0494@2|Bacteria 2|Bacteria L nUDIX hydrolase - - - - - - - - - - - - NUDIX SJTD3_k127_6506512_1 926560.KE387027_gene705 5.649e-48 174.0 COG2044@1|root,COG2044@2|Bacteria 2|Bacteria - - - - - ko:K06039,ko:K07092 - - - - ko00000 - - - DrsE SJTD3_k127_6506512_4 926560.KE387027_gene706 6.063e-16 81.0 COG0425@1|root,COG0425@2|Bacteria 2|Bacteria O sulfur carrier activity - - 2.1.1.14 ko:K00549,ko:K04085 ko00270,ko00450,ko01100,ko01110,ko01230,ko04122,map00270,map00450,map01100,map01110,map01230,map04122 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000,ko03016 - - - Meth_synt_2,OsmC,SnoaL_2,TusA SJTD3_k127_6506512_5 485913.Krac_10670 0.0006046 44.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulator, LuxR family - - - - - - - - - - - - AAA_22,GerE,NB-ARC,TPR_12 SJTD3_k127_6508597_4 1463825.JNXC01000031_gene1589 7.418e-44 165.0 COG0673@1|root,COG0673@2|Bacteria,2IFZE@201174|Actinobacteria,4ECGC@85010|Pseudonocardiales 201174|Actinobacteria S Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C,ox_reductase_C SJTD3_k127_6508597_0 706587.Desti_5544 2.308e-88 309.0 COG0683@1|root,COG0683@2|Bacteria,1N76S@1224|Proteobacteria,42RNG@68525|delta/epsilon subdivisions,2WNA9@28221|Deltaproteobacteria 28221|Deltaproteobacteria E Receptor family ligand binding region - - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 SJTD3_k127_6508597_1 1122622.ATWJ01000007_gene1878 2.854e-82 283.0 COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4FFXG@85021|Intrasporangiaceae 201174|Actinobacteria E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SJTD3_k127_6508597_3 640081.Dsui_2059 1.049e-65 237.0 COG4177@1|root,COG4177@2|Bacteria,1MV66@1224|Proteobacteria,2VM4B@28216|Betaproteobacteria,2KZ2Q@206389|Rhodocyclales 206389|Rhodocyclales P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SJTD3_k127_6508597_2 1146883.BLASA_1603 7.2e-76 264.0 COG0411@1|root,COG4177@1|root,COG0411@2|Bacteria,COG4177@2|Bacteria,2GMEE@201174|Actinobacteria,4EURK@85013|Frankiales 201174|Actinobacteria P Belongs to the binding-protein-dependent transport system permease family - - - ko:K01995,ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C,BPD_transp_2 SJTD3_k127_6508597_5 1280685.AUKC01000031_gene968 8.279e-26 120.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,4BXW9@830|Butyrivibrio 186801|Clostridia E ABC transporter livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran SJTD3_k127_6591665_3 1243664.CAVL020000019_gene3581 6.313e-20 98.0 COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9N3@91061|Bacilli,1ZBKV@1386|Bacillus 91061|Bacilli L Metallo-beta-lactamase superfamily - - - - - - - - - - - - Excalibur,HHH_3,LTD,Lactamase_B,SLH SJTD3_k127_6591665_0 35754.JNYJ01000019_gene80 2.037e-131 451.0 COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales 201174|Actinobacteria KT Transcriptional regulator - - - - - - - - - - - - AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12 SJTD3_k127_6591665_1 1047013.AQSP01000094_gene17 5.558e-95 321.0 COG1397@1|root,COG1397@2|Bacteria,2NPWB@2323|unclassified Bacteria 2|Bacteria O ADP-ribosylglycohydrolase draG - 3.2.2.24 ko:K05521 - - - - ko00000,ko01000 - - - ADP_ribosyl_GH SJTD3_k127_6617165_1 292459.STH807 6.603e-68 238.0 COG2267@1|root,COG2267@2|Bacteria,1TPI0@1239|Firmicutes,247QR@186801|Clostridia 186801|Clostridia I Alpha beta hydrolase - - 1.11.1.10,3.1.1.24 ko:K00433,ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 M00568 R02991 RC00825 ko00000,ko00001,ko00002,ko01000 - - - Abhydrolase_1,Abhydrolase_4 SJTD3_k127_6617165_0 1521187.JPIM01000020_gene228 3.461e-93 320.0 COG0596@1|root,COG0596@2|Bacteria,2G9A9@200795|Chloroflexi,376PI@32061|Chloroflexia 32061|Chloroflexia S PFAM alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_6617165_2 604331.AUHY01000021_gene1991 4.349e-31 124.0 COG2267@1|root,COG2267@2|Bacteria,1WMAU@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 SJTD3_k127_6624956_1 383372.Rcas_0154 4.011e-70 258.0 2DZNW@1|root,32VEY@2|Bacteria,2G8XI@200795|Chloroflexi,374W5@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_6624956_0 479434.Sthe_1749 9.627e-78 273.0 COG2870@1|root,COG2870@2|Bacteria,2G6G0@200795|Chloroflexi,27Y48@189775|Thermomicrobia 189775|Thermomicrobia M pfkB family carbohydrate kinase - - - - - - - - - - - - PfkB SJTD3_k127_6624956_3 479434.Sthe_1748 1.957e-26 116.0 COG3063@1|root,COG3063@2|Bacteria,2G79Z@200795|Chloroflexi,27YJ3@189775|Thermomicrobia 189775|Thermomicrobia NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - - SJTD3_k127_6624956_2 378806.STAUR_8371 5.217e-35 134.0 COG3832@1|root,COG3832@2|Bacteria,1RCZK@1224|Proteobacteria,432IJ@68525|delta/epsilon subdivisions,2WYDE@28221|Deltaproteobacteria,2Z02P@29|Myxococcales 28221|Deltaproteobacteria S Activator of Hsp90 ATPase homolog 1-like protein - - - - - - - - - - - - AHSA1 SJTD3_k127_6625812_1 1395516.PMO01_11480 1.436e-42 160.0 COG2050@1|root,COG2050@2|Bacteria,1RBPE@1224|Proteobacteria,1SCN1@1236|Gammaproteobacteria 1236|Gammaproteobacteria Q PFAM thioesterase superfamily - - - - - - - - - - - - 4HBT SJTD3_k127_6625812_0 383372.Rcas_2066 1.489e-116 384.0 COG0006@1|root,COG0006@2|Bacteria,2G5J8@200795|Chloroflexi,376NM@32061|Chloroflexia 32061|Chloroflexia E PFAM peptidase M24 - - - - - - - - - - - - Peptidase_M24 SJTD3_k127_6634293_2 391589.RGAI101_3821 1.532e-113 388.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria 1224|Proteobacteria S amidohydrolase abgA GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009109,GO:0009111,GO:0009397,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0019439,GO:0019752,GO:0034641,GO:0042219,GO:0042365,GO:0042558,GO:0042560,GO:0042737,GO:0043436,GO:0043603,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046655,GO:0046657,GO:0046700,GO:0046982,GO:0046983,GO:0051186,GO:0051187,GO:0071704,GO:0071713,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 - ko:K12940 - - - - ko00000,ko01002 - - - M20_dimer,Peptidase_M20 SJTD3_k127_6634293_0 634177.GLX_00700 2.826e-136 452.0 COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TQR1@28211|Alphaproteobacteria 28211|Alphaproteobacteria C belongs to the aldehyde dehydrogenase family aldA - 1.2.1.3 ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 M00135 R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146 RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500 ko00000,ko00001,ko00002,ko01000 - - - Aldedh SJTD3_k127_6634293_5 395494.Galf_1808 1.16e-14 85.0 COG1879@1|root,COG1879@2|Bacteria,1MXQN@1224|Proteobacteria,2VS1W@28216|Betaproteobacteria 28216|Betaproteobacteria G Periplasmic binding protein LacI transcriptional regulator torT - - ko:K11930 - - - - ko00000 - - - Peripla_BP_1,Peripla_BP_4 SJTD3_k127_6634293_3 1403313.AXBR01000028_gene5047 3.724e-76 269.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,4H9Y3@91061|Bacilli,1ZBAZ@1386|Bacillus 91061|Bacilli G Belongs to the binding-protein-dependent transport system permease family rbsC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_6634293_1 309799.DICTH_0297 1.564e-132 440.0 COG1129@1|root,COG1129@2|Bacteria 2|Bacteria G ABC transporter rbsA - 3.6.3.17 ko:K10441,ko:K10562 ko02010,map02010 M00212,M00220 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.9 - - ABC_tran SJTD3_k127_6634293_4 1415166.NONO_c27280 8.599e-51 186.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4FZWH@85025|Nocardiaceae 201174|Actinobacteria C alcohol dehydrogenase - - - - - - - - - - - - Fe-ADH SJTD3_k127_6650709_0 204669.Acid345_2313 1.199e-40 164.0 2AZDP@1|root,31RMA@2|Bacteria,3Y4JB@57723|Acidobacteria,2JJ76@204432|Acidobacteriia 204432|Acidobacteriia S Protein of unknown function (DUF4230) - - - - - - - - - - - - DUF4230 SJTD3_k127_6679103_2 1206730.BAGA01000177_gene4634 4.792e-10 65.0 COG1262@1|root,COG2319@1|root,COG1262@2|Bacteria,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria,4FUSK@85025|Nocardiaceae 201174|Actinobacteria L WD40 repeats - - - - - - - - - - - - AAA_16,PD40,TIR_2,WD40 SJTD3_k127_6679103_0 1184267.A11Q_1402 9.19e-49 199.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,42MFK@68525|delta/epsilon subdivisions,2MTSI@213481|Bdellovibrionales,2WKBU@28221|Deltaproteobacteria 213481|Bdellovibrionales E extracellular solute-binding protein, family 5 - - - ko:K02035 ko02024,map02024 M00239 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5 - - SBP_bac_5 SJTD3_k127_6679103_1 1382356.JQMP01000004_gene653 1.588e-36 160.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_6679103_3 1487953.JMKF01000072_gene3522 0.0001187 48.0 COG2197@1|root,COG2197@2|Bacteria,1G89I@1117|Cyanobacteria,1HCKV@1150|Oscillatoriales 1117|Cyanobacteria KT helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE SJTD3_k127_6743973_2 1047013.AQSP01000138_gene1054 2.019e-14 85.0 2DTK7@1|root,33KQU@2|Bacteria,2NRAS@2323|unclassified Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_6743973_0 926569.ANT_09910 5.866e-63 228.0 COG0682@1|root,COG0682@2|Bacteria,2G6QJ@200795|Chloroflexi 200795|Chloroflexi M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT SJTD3_k127_6743973_1 1499967.BAYZ01000103_gene3780 1.291e-16 92.0 COG0457@1|root,COG0457@2|Bacteria 1499967.BAYZ01000103_gene3780|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SJTD3_k127_6754431_1 926569.ANT_00800 1.48e-93 319.0 COG1215@1|root,COG1215@2|Bacteria,2G6RJ@200795|Chloroflexi 200795|Chloroflexi M PFAM Glycosyl transferase family 2 - - - ko:K14597 ko00906,map00906 - R07544,R07546 RC00262 ko00000,ko00001 - - - Glycos_transf_2 SJTD3_k127_6754431_0 926550.CLDAP_20410 4.695e-132 435.0 COG2124@1|root,COG2124@2|Bacteria,2G623@200795|Chloroflexi 2|Bacteria C PFAM Cytochrome P450 cyp139A3 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0016125,GO:0016491,GO:0030312,GO:0044238,GO:0044464,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901615 - - - - - - - - - - p450 SJTD3_k127_6754431_2 889378.Spiaf_1285 1.737e-37 147.0 COG0654@1|root,COG0654@2|Bacteria 2|Bacteria CH COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases crtL - 5.5.1.19 ko:K06443 ko00906,ko01100,ko01110,map00906,map01100,map01110 M00097 R03824,R04801,R05341,R06962,R07856 RC01004,RC01964 ko00000,ko00001,ko00002,ko01000 - - - Lycopene_cycl SJTD3_k127_6755494_0 251229.Chro_4403 7.837e-238 750.0 COG0068@1|root,COG0068@2|Bacteria,1G063@1117|Cyanobacteria,3VI6E@52604|Pleurocapsales 1117|Cyanobacteria O PFAM HypF finger hypF - - ko:K04656 - - - - ko00000 - - - Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF SJTD3_k127_6755494_2 1173024.KI912153_gene217 4.716e-115 381.0 COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,1JKMZ@1189|Stigonemataceae 1117|Cyanobacteria F Dihydroorotate dehydrogenase - - 1.3.98.1 ko:K00226 ko00240,ko01100,map00240,map01100 M00051 R01867 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh SJTD3_k127_6755494_1 518766.Rmar_2595 1.612e-182 576.0 COG0409@1|root,COG0409@2|Bacteria,4NIM8@976|Bacteroidetes 976|Bacteroidetes O TIGRFAM hydrogenase expression formation protein HypD - - - ko:K04654 - - - - ko00000 - - - HypD SJTD3_k127_6755494_3 251229.Chro_4409 8.955e-63 218.0 COG0309@1|root,COG0309@2|Bacteria,1G1Z7@1117|Cyanobacteria,3VJ6M@52604|Pleurocapsales 1117|Cyanobacteria O PFAM AIR synthase related protein, N-terminal domain hypE - - ko:K04655 - - - - ko00000 - - - AIRS,AIRS_C SJTD3_k127_6758417_2 936455.KI421499_gene5437 1.221e-09 63.0 COG1309@1|root,COG1309@2|Bacteria,1R6IU@1224|Proteobacteria,2TUD7@28211|Alphaproteobacteria,3JUNQ@41294|Bradyrhizobiaceae 28211|Alphaproteobacteria K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N SJTD3_k127_6758417_0 479434.Sthe_0104 2.692e-72 258.0 COG4447@1|root,COG4447@2|Bacteria,2G8DW@200795|Chloroflexi,27YX3@189775|Thermomicrobia 189775|Thermomicrobia S cellulose binding - - - - - - - - - - - - - SJTD3_k127_676307_0 1521187.JPIM01000038_gene3830 1.837e-81 292.0 COG0534@1|root,COG0534@2|Bacteria,2G78S@200795|Chloroflexi,375PA@32061|Chloroflexia 32061|Chloroflexia V PFAM multi antimicrobial extrusion protein MatE - - - - - - - - - - - - MatE SJTD3_k127_676307_1 379066.GAU_0613 5.597e-44 172.0 COG0697@1|root,COG0697@2|Bacteria,1ZTNS@142182|Gemmatimonadetes 142182|Gemmatimonadetes EG EamA-like transporter family - - - - - - - - - - - - EamA SJTD3_k127_676307_2 479435.Kfla_3931 1.588e-32 134.0 COG3871@1|root,COG3871@2|Bacteria,2IFC3@201174|Actinobacteria 201174|Actinobacteria S stress protein (general stress protein 26) - - - - - - - - - - - - Putative_PNPOx SJTD3_k127_676307_3 324602.Caur_1112 1.528e-23 107.0 COG2120@1|root,COG2120@2|Bacteria,2G6YU@200795|Chloroflexi,375SK@32061|Chloroflexia 32061|Chloroflexia S PFAM LmbE family protein - - - - - - - - - - - - PIG-L SJTD3_k127_6763132_0 485913.Krac_4435 1.324e-56 201.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 SJTD3_k127_6763132_2 1501230.ET33_09785 4.048e-24 111.0 COG0454@1|root,COG0456@2|Bacteria,1UJQK@1239|Firmicutes,4ITD7@91061|Bacilli,277CT@186822|Paenibacillaceae 91061|Bacilli K Acetyltransferase (GNAT) domain - - 2.3.1.57 ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 M00135 R01154 RC00004,RC00096 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1 SJTD3_k127_6763132_1 1380391.JIAS01000015_gene178 1.893e-48 179.0 2E1J9@1|root,32WWY@2|Bacteria,1Q7D3@1224|Proteobacteria,2UTHG@28211|Alphaproteobacteria 28211|Alphaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_6763132_3 649764.HMPREF0762_00257 5.7e-07 53.0 COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4CUBG@84998|Coriobacteriia 84998|Coriobacteriia L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - - SJTD3_k127_6770875_4 311424.DhcVS_1008 1.492e-48 183.0 COG0127@1|root,COG0127@2|Bacteria,2G6GK@200795|Chloroflexi,34CM3@301297|Dehalococcoidia 301297|Dehalococcoidia F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions - - 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like SJTD3_k127_6770875_5 1122182.KB903825_gene872 2.098e-45 180.0 COG1051@1|root,COG1051@2|Bacteria,2HWVF@201174|Actinobacteria,4DKH0@85008|Micromonosporales 201174|Actinobacteria F Hydrolase of X-linked nucleoside diphosphate N terminal - - - - - - - - - - - - NUDIX,Nudix_N SJTD3_k127_6770875_2 1356854.N007_17585 5.113e-61 218.0 COG0500@1|root,COG2226@2|Bacteria,1V261@1239|Firmicutes,4HI81@91061|Bacilli 91061|Bacilli Q O-methyltransferase - - - ko:K15256 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_25 SJTD3_k127_6770875_1 450851.PHZ_c0577 2.749e-146 472.0 COG2189@1|root,COG2189@2|Bacteria,1MX9M@1224|Proteobacteria,2TSW9@28211|Alphaproteobacteria,2KFGB@204458|Caulobacterales 204458|Caulobacterales L Belongs to the N(4) N(6)-methyltransferase family - - 2.1.1.72 ko:K13581 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko02048 - - - N6_N4_Mtase SJTD3_k127_6770875_3 1034769.KB910518_gene414 6.046e-59 211.0 COG1397@1|root,COG1397@2|Bacteria,1VCRW@1239|Firmicutes 1239|Firmicutes O methyltransferase - - - - - - - - - - - - - SJTD3_k127_6770875_0 247490.KSU1_C0714 2.262e-169 554.0 COG1404@1|root,COG1404@2|Bacteria,2IZNN@203682|Planctomycetes 203682|Planctomycetes O alpha-L-arabinofuranosidase - - - - - - - - - - - - SBBP SJTD3_k127_6771333_0 383372.Rcas_3820 5.577e-78 282.0 COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia 32061|Chloroflexia S von Willebrand factor, type A - - - - - - - - - - - - BatA,VWA_2 SJTD3_k127_6771975_4 525904.Tter_1861 2.34e-25 106.0 COG2141@1|root,COG2141@2|Bacteria,2NQJG@2323|unclassified Bacteria 2|Bacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_6771975_0 266117.Rxyl_0973 1.835e-116 385.0 COG0778@1|root,COG3576@1|root,COG0778@2|Bacteria,COG3576@2|Bacteria,2I2U7@201174|Actinobacteria,4CU67@84995|Rubrobacteria 84995|Rubrobacteria C Nitroreductase family - - - - - - - - - - - - Nitroreductase SJTD3_k127_6771975_2 266117.Rxyl_1056 2.431e-53 190.0 COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4CQU0@84995|Rubrobacteria 84995|Rubrobacteria S Pfam:Pyridox_oxidase - - - - - - - - - - - - Putative_PNPOx SJTD3_k127_6771975_1 521098.Aaci_0861 2.184e-63 223.0 COG2353@1|root,COG2353@2|Bacteria,1V1NX@1239|Firmicutes,4HFXF@91061|Bacilli 91061|Bacilli S Belongs to the UPF0312 family - - - - - - - - - - - - YceI SJTD3_k127_6771975_3 485913.Krac_11351 3.905e-29 121.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - MarR SJTD3_k127_6774495_1 1382306.JNIM01000001_gene725 1.595e-82 280.0 COG1215@1|root,COG1215@2|Bacteria,2GBNZ@200795|Chloroflexi 200795|Chloroflexi M Glycosyltransferase like family 2 - - 2.4.1.83 ko:K00721 ko00510,ko01100,map00510,map01100 - R01009 RC00005 ko00000,ko00001,ko01000,ko01003 - GT2 - Glycos_transf_2 SJTD3_k127_6774495_4 937774.TEQUI_0062 2.281e-23 110.0 COG1430@1|root,COG1430@2|Bacteria,1MZBJ@1224|Proteobacteria,2VSCK@28216|Betaproteobacteria,3T4GB@506|Alcaligenaceae 28216|Betaproteobacteria S Uncharacterized ACR, COG1430 - - - ko:K09005 - - - - ko00000 - - - DUF192 SJTD3_k127_6774495_0 485913.Krac_11275 6.295e-101 347.0 COG4956@1|root,COG4956@2|Bacteria,2G5YK@200795|Chloroflexi 200795|Chloroflexi S SMART Nucleotide binding protein, PINc - - - - - - - - - - - - TRAM SJTD3_k127_6774495_3 1380763.BG53_15455 2.71e-51 191.0 COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,4HH2N@91061|Bacilli,26QP8@186822|Paenibacillaceae 91061|Bacilli I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) ispD GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633 RC00002 ko00000,ko00001,ko00002,ko01000 - - - IspD SJTD3_k127_6774495_2 1378168.N510_02444 2.157e-55 198.0 COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes 1239|Firmicutes I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) ispF - 2.7.7.60,4.6.1.12 ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00096 R05633,R05637 RC00002,RC01440 ko00000,ko00001,ko00002,ko01000 - - - IspD,YgbB SJTD3_k127_6791610_1 1408422.JHYF01000002_gene2199 5.097e-38 146.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,36EB6@31979|Clostridiaceae 186801|Clostridia EJ L-asparaginase ansA - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase SJTD3_k127_6791610_0 1382356.JQMP01000003_gene2039 2.323e-75 267.0 COG2848@1|root,COG2848@2|Bacteria,2G6HQ@200795|Chloroflexi,27YZX@189775|Thermomicrobia 189775|Thermomicrobia S Uncharacterised ACR (DUF711) - - - ko:K09157 - - - - ko00000 - - - DUF711 SJTD3_k127_6831240_1 309801.trd_1051 1.115e-10 72.0 COG5662@1|root,COG5662@2|Bacteria,2GBGZ@200795|Chloroflexi,27XXW@189775|Thermomicrobia 189775|Thermomicrobia K Putative zinc-finger - - - - - - - - - - - - zf-HC2 SJTD3_k127_6831240_0 479434.Sthe_0470 5.38e-66 233.0 COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,27YAG@189775|Thermomicrobia 189775|Thermomicrobia K Belongs to the sigma-70 factor family. ECF subfamily - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_6836460_29 316274.Haur_1183 4.523e-26 123.0 COG2866@1|root,COG2866@2|Bacteria,2G7U3@200795|Chloroflexi 200795|Chloroflexi E Zn_pept - - - - - - - - - - - - Peptidase_M14 SJTD3_k127_6836460_37 1123290.AUDQ01000022_gene745 1.522e-08 67.0 COG0791@1|root,COG0791@2|Bacteria,1V9FW@1239|Firmicutes,4HISN@91061|Bacilli,26FSP@186818|Planococcaceae 91061|Bacilli M S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_6836460_0 479434.Sthe_0389 1.684e-152 488.0 COG4608@1|root,COG4608@2|Bacteria,2G5R5@200795|Chloroflexi,27XY8@189775|Thermomicrobia 189775|Thermomicrobia P Belongs to the ABC transporter superfamily - - - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY SJTD3_k127_6836460_2 1128421.JAGA01000002_gene833 6.785e-142 457.0 COG0444@1|root,COG0444@2|Bacteria,2NQAA@2323|unclassified Bacteria 2|Bacteria P Oligopeptide/dipeptide transporter, C-terminal region oppD - - ko:K02031,ko:K02032,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY SJTD3_k127_6836460_6 867903.ThesuDRAFT_01162 1.991e-83 286.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WD2P@538999|Clostridiales incertae sedis 186801|Clostridia EP N-terminal TM domain of oligopeptide transport permease C oppC - - ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N SJTD3_k127_6836460_15 311424.DhcVS_931 1.055e-60 216.0 COG0601@1|root,COG0601@2|Bacteria,2G9WT@200795|Chloroflexi,34DMG@301297|Dehalococcoidia 301297|Dehalococcoidia P Binding-protein-dependent transport system inner membrane component - - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 SJTD3_k127_6836460_35 1472716.KBK24_0109260 2.363e-10 68.0 COG0601@1|root,COG0601@2|Bacteria,1MU8Z@1224|Proteobacteria,2VJG6@28216|Betaproteobacteria,1K3CX@119060|Burkholderiaceae 28216|Betaproteobacteria P PFAM binding-protein-dependent transport systems inner membrane component oppB - - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 SJTD3_k127_6836460_13 796606.BMMGA3_08820 6.74e-62 236.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,4HAMK@91061|Bacilli,1ZBB4@1386|Bacillus 91061|Bacilli E ABC transporter substrate-binding protein dppE GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - ko:K16199 ko02010,map02010 M00566 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.2 - - SBP_bac_5 SJTD3_k127_6836460_21 479434.Sthe_1068 9.363e-48 175.0 COG0103@1|root,COG0103@2|Bacteria,2G6UZ@200795|Chloroflexi,27YEC@189775|Thermomicrobia 189775|Thermomicrobia J Belongs to the universal ribosomal protein uS9 family rpsI - - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 SJTD3_k127_6836460_20 479434.Sthe_1067 1.989e-51 189.0 COG0102@1|root,COG0102@2|Bacteria,2G6M4@200795|Chloroflexi,27YCR@189775|Thermomicrobia 189775|Thermomicrobia J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM - - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 SJTD3_k127_6836460_18 1521187.JPIM01000007_gene1408 2.633e-56 207.0 COG0101@1|root,COG0101@2|Bacteria,2G6PE@200795|Chloroflexi,375JX@32061|Chloroflexia 32061|Chloroflexia J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 SJTD3_k127_6836460_28 1430440.MGMSRv2_0063 2.467e-29 120.0 COG0203@1|root,COG0203@2|Bacteria,1RCWN@1224|Proteobacteria,2U749@28211|Alphaproteobacteria,2JS9R@204441|Rhodospirillales 204441|Rhodospirillales J Ribosomal protein L17 rplQ - - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 SJTD3_k127_6836460_3 357808.RoseRS_1158 5.411e-102 347.0 COG0202@1|root,COG0202@2|Bacteria,2G5M9@200795|Chloroflexi,3751M@32061|Chloroflexia 32061|Chloroflexia K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA - 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L SJTD3_k127_6836460_7 1382356.JQMP01000003_gene2287 1.354e-79 270.0 COG0522@1|root,COG0522@2|Bacteria,2G6AZ@200795|Chloroflexi,27XMY@189775|Thermomicrobia 189775|Thermomicrobia J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit - - - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 SJTD3_k127_6836460_17 485913.Krac_12503 1.507e-56 200.0 COG0100@1|root,COG0100@2|Bacteria,2G6HG@200795|Chloroflexi 200795|Chloroflexi J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK - - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 SJTD3_k127_6836460_19 429009.Adeg_1499 4.945e-55 194.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,42G97@68295|Thermoanaerobacterales 186801|Clostridia J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM - - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 SJTD3_k127_6836460_36 699246.HMPREF0868_1515 1.809e-09 63.0 COG0257@1|root,COG0257@2|Bacteria,1VK4F@1239|Firmicutes,24UGF@186801|Clostridia,269WB@186813|unclassified Clostridiales 186801|Clostridia J Belongs to the bacterial ribosomal protein bL36 family rpmJ - - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 SJTD3_k127_6836460_31 640132.Srot_2511 2.526e-21 96.0 COG0361@1|root,COG0361@2|Bacteria,2IQ4B@201174|Actinobacteria 201174|Actinobacteria J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071944 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a SJTD3_k127_6836460_5 401526.TcarDRAFT_1018 6.865e-88 297.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H2VZ@909932|Negativicutes 909932|Negativicutes E Methionine aminopeptidase map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 SJTD3_k127_6836460_10 795359.TOPB45_0774 2.78e-70 245.0 COG0563@1|root,COG0563@2|Bacteria,2GGXU@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk - 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid SJTD3_k127_6836460_1 525904.Tter_0735 3.424e-148 481.0 COG0201@1|root,COG0201@2|Bacteria,2NNVK@2323|unclassified Bacteria 2|Bacteria U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY SJTD3_k127_6836460_25 316274.Haur_4933 6.102e-40 155.0 COG0200@1|root,COG0200@2|Bacteria,2G6T9@200795|Chloroflexi,375PW@32061|Chloroflexia 32061|Chloroflexia J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A SJTD3_k127_6836460_33 479434.Sthe_1054 1.311e-16 87.0 COG1841@1|root,COG1841@2|Bacteria,2G7E7@200795|Chloroflexi,27YRK@189775|Thermomicrobia 189775|Thermomicrobia J Ribosomal protein L30p/L7e rpmD - - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 SJTD3_k127_6836460_14 479434.Sthe_1053 1.67e-61 220.0 COG0098@1|root,COG0098@2|Bacteria,2G6M9@200795|Chloroflexi,27YA8@189775|Thermomicrobia 189775|Thermomicrobia J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE - - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C SJTD3_k127_6836460_23 936154.STP_0064 1.446e-41 156.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p SJTD3_k127_6836460_9 1121272.KB903250_gene2991 4.799e-71 244.0 COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4DAXG@85008|Micromonosporales 201174|Actinobacteria J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 SJTD3_k127_6836460_22 1045854.WKK_02650 2.62e-45 167.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli,4AXQW@81850|Leuconostocaceae 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 SJTD3_k127_6836460_30 1089553.Tph_c25720 2.681e-25 105.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,42H2Z@68295|Thermoanaerobacterales 186801|Clostridia J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 SJTD3_k127_6836460_8 1382306.JNIM01000001_gene3537 4.34e-76 266.0 COG0094@1|root,COG0094@2|Bacteria,2G6C6@200795|Chloroflexi 200795|Chloroflexi J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C SJTD3_k127_6836460_27 697329.Rumal_0047 1.558e-32 130.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3WJBH@541000|Ruminococcaceae 186801|Clostridia J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX - - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 SJTD3_k127_6836460_16 685727.REQ_35760 6.001e-58 203.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4G17I@85025|Nocardiaceae 201174|Actinobacteria J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 SJTD3_k127_6836460_32 471853.Bcav_3134 1.162e-20 96.0 COG0186@1|root,COG0186@2|Bacteria,2IQ68@201174|Actinobacteria 201174|Actinobacteria J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 SJTD3_k127_6836460_34 1379281.AVAG01000008_gene1368 7.168e-12 70.0 COG0255@1|root,COG0255@2|Bacteria,1Q1R3@1224|Proteobacteria,42WYX@68525|delta/epsilon subdivisions,2WSTS@28221|Deltaproteobacteria,2MD3F@213115|Desulfovibrionales 28221|Deltaproteobacteria J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 SJTD3_k127_6836460_11 525904.Tter_0722 5.828e-66 228.0 COG0197@1|root,COG0197@2|Bacteria,2NPC6@2323|unclassified Bacteria 2|Bacteria J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 SJTD3_k127_6836460_4 383372.Rcas_4020 1.339e-93 321.0 COG0092@1|root,COG0092@2|Bacteria,2G691@200795|Chloroflexi,3757R@32061|Chloroflexia 32061|Chloroflexia J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C SJTD3_k127_6836460_26 457570.Nther_0199 3.686e-35 136.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia 186801|Clostridia J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV - - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 SJTD3_k127_6836460_24 525904.Tter_0719 1.203e-40 151.0 COG0185@1|root,COG0185@2|Bacteria,2NPIV@2323|unclassified Bacteria 2|Bacteria J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 SJTD3_k127_6836460_12 1128421.JAGA01000002_gene700 6.009e-65 224.0 COG0090@1|root,COG0090@2|Bacteria,2NNR3@2323|unclassified Bacteria 2|Bacteria J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C SJTD3_k127_683952_7 1122226.AUHX01000004_gene1734 1.652e-09 62.0 COG1609@1|root,COG1609@2|Bacteria,4NESN@976|Bacteroidetes,1I1GK@117743|Flavobacteriia 976|Bacteroidetes K transcriptional regulator - - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4 SJTD3_k127_683952_4 1445613.JALM01000020_gene4722 5.314e-68 246.0 COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4E3AX@85010|Pseudonocardiales 201174|Actinobacteria C Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_683952_2 1151118.KB895789_gene908 2.269e-97 328.0 COG0673@1|root,COG0673@2|Bacteria,2GMPY@201174|Actinobacteria 201174|Actinobacteria S Oxidoreductase - - - ko:K03810 - - - - ko00000 - - - GFO_IDH_MocA SJTD3_k127_683952_5 666510.ASAC_0064 1.533e-29 130.0 COG0451@1|root,arCOG01369@2157|Archaea,2XQCJ@28889|Crenarchaeota 28889|Crenarchaeota M PFAM NAD-dependent epimerase dehydratase - - 4.1.1.35,5.1.3.2 ko:K01784,ko:K08678 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R01384,R02984 RC00289,RC00508 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd SJTD3_k127_683952_1 1211115.ALIQ01000005_gene4346 2.053e-103 344.0 COG1116@1|root,COG1116@2|Bacteria,1MUDV@1224|Proteobacteria,2TSH9@28211|Alphaproteobacteria,3NC0A@45404|Beijerinckiaceae 28211|Alphaproteobacteria P ATPases associated with a variety of cellular activities - - - ko:K02049 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - ABC_tran SJTD3_k127_683952_0 1211115.ALIQ01000005_gene4347 2.168e-125 413.0 COG0715@1|root,COG0715@2|Bacteria,1MW53@1224|Proteobacteria,2TSHF@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - NMT1 SJTD3_k127_683952_3 1211115.ALIQ01000005_gene4348 3.47e-94 320.0 COG0600@1|root,COG0600@2|Bacteria,1MVAE@1224|Proteobacteria,2VF1T@28211|Alphaproteobacteria 28211|Alphaproteobacteria P ABC-type nitrate sulfonate bicarbonate transport system permease component - - - ko:K02050 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - BPD_transp_1 SJTD3_k127_683952_6 883066.HMPREF9233_00455 9.852e-19 92.0 COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4D73N@85005|Actinomycetales 201174|Actinobacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA_1 - 3.5.4.22,4.3.3.7 ko:K01714,ko:K21062 ko00261,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00330,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R02280,R10147 RC00679,RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS SJTD3_k127_6876641_1 765420.OSCT_2099 4.877e-18 87.0 COG1287@1|root,COG1287@2|Bacteria,2GBKX@200795|Chloroflexi,3781U@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_6876641_0 358396.C445_20052 1.403e-91 325.0 arCOG02329@1|root,arCOG02348@1|root,arCOG02360@1|root,arCOG07605@1|root,arCOG02329@2157|Archaea,arCOG02348@2157|Archaea,arCOG02360@2157|Archaea,arCOG07605@2157|Archaea,2Y5ZU@28890|Euryarchaeota 28890|Euryarchaeota T Histidine kinase - - - - - - - - - - - - GAF,HATPase_c,HisKA,HisKA_4TM,PAS_4,PAS_9 SJTD3_k127_6876641_2 762903.Pedsa_2767 8.46e-13 68.0 COG0861@1|root,COG0861@2|Bacteria,4NFFD@976|Bacteroidetes,1IQQC@117747|Sphingobacteriia 976|Bacteroidetes P Membrane protein TerC, possibly involved in tellurium resistance - - - - - - - - - - - - TerC SJTD3_k127_6877239_0 485913.Krac_4187 6.601e-87 296.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 SJTD3_k127_6880522_6 497964.CfE428DRAFT_1005 1.126e-05 49.0 COG0438@1|root,COG0438@2|Bacteria,46U6V@74201|Verrucomicrobia 74201|Verrucomicrobia M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_6880522_1 479434.Sthe_2411 3.943e-67 253.0 COG2203@1|root,COG3290@1|root,COG5002@1|root,COG2203@2|Bacteria,COG3290@2|Bacteria,COG5002@2|Bacteria,2G7SE@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - 2.7.13.3 ko:K07636 ko02020,map02020 M00434 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GAF_2,HATPase_c,HisKA,PAS_4 SJTD3_k127_6880522_5 311424.DhcVS_94 8.289e-10 72.0 COG0745@1|root,COG0745@2|Bacteria,2G5ND@200795|Chloroflexi,34DEA@301297|Dehalococcoidia 301297|Dehalococcoidia K Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C SJTD3_k127_6880522_2 1123368.AUIS01000004_gene121 3.655e-43 164.0 COG0784@1|root,COG0784@2|Bacteria,1QUN7@1224|Proteobacteria,1T3Z8@1236|Gammaproteobacteria 1236|Gammaproteobacteria T Response regulator receiver - - - ko:K02485 - - - - ko00000,ko02022 - - - Response_reg SJTD3_k127_6880522_3 479434.Sthe_2397 1.278e-25 115.0 COG0748@1|root,COG0748@2|Bacteria 2|Bacteria P coenzyme F420 binding - - - - - - - - - - - - F420H2_quin_red SJTD3_k127_6880522_0 1121272.KB903290_gene4678 1.694e-114 379.0 2C1EG@1|root,2Z7MZ@2|Bacteria,2GK4W@201174|Actinobacteria,4DHRJ@85008|Micromonosporales 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_6880522_4 1123368.AUIS01000032_gene1389 2.782e-17 83.0 COG3360@1|root,COG3360@2|Bacteria 2|Bacteria P Dodecin secE2 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - ko:K09165 - - - - ko00000 - - - Dodecin SJTD3_k127_6881338_2 309801.trd_1199 9.731e-65 229.0 COG2738@1|root,COG2738@2|Bacteria,2G6KQ@200795|Chloroflexi,27YW2@189775|Thermomicrobia 189775|Thermomicrobia S Putative neutral zinc metallopeptidase - - - ko:K06973 - - - - ko00000 - - - Zn_peptidase_2 SJTD3_k127_6881338_1 1382306.JNIM01000001_gene642 4.075e-69 252.0 COG0665@1|root,COG0665@2|Bacteria,2G80C@200795|Chloroflexi 200795|Chloroflexi C PFAM FAD dependent oxidoreductase - - 1.5.3.1 ko:K00301 ko00260,ko01100,map00260,map01100 - R00610 RC00060,RC00557 ko00000,ko00001,ko01000 - - - DAO SJTD3_k127_6881338_0 525904.Tter_1451 4.73e-112 381.0 COG1249@1|root,COG1249@2|Bacteria,2NNTI@2323|unclassified Bacteria 2|Bacteria C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Pyr_redox_2,Pyr_redox_dim SJTD3_k127_6881338_3 1235279.C772_01192 7.664e-56 206.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4HABG@91061|Bacilli,26EK3@186818|Planococcaceae 91061|Bacilli H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation lipM GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB SJTD3_k127_6881338_4 765420.OSCT_1302 1.621e-28 116.0 COG0379@1|root,COG0379@2|Bacteria,2G64Y@200795|Chloroflexi,375TJ@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate nadA - 2.5.1.72 ko:K03517 ko00760,ko01100,map00760,map01100 M00115 R04292 RC01119 ko00000,ko00001,ko00002,ko01000 - - - NadA SJTD3_k127_6883572_4 1121924.ATWH01000001_gene4463 1.617e-27 121.0 COG1266@1|root,COG1266@2|Bacteria,2I8AH@201174|Actinobacteria,4FREE@85023|Microbacteriaceae 201174|Actinobacteria S CAAX protease self-immunity - - - - - - - - - - - - Abi SJTD3_k127_6883572_3 861299.J421_1425 4.827e-52 196.0 COG0682@1|root,COG0682@2|Bacteria 2|Bacteria M lipoprotein biosynthetic process - - - ko:K13292 - - - - ko00000,ko01000 - - - LGT SJTD3_k127_6883572_1 1122611.KB903952_gene5905 2.66e-149 488.0 COG1964@1|root,COG1964@2|Bacteria,2I9RQ@201174|Actinobacteria 201174|Actinobacteria Q Radical SAM - - - ko:K06937 - - - - ko00000,ko01000 - - - Fer4_12,Radical_SAM SJTD3_k127_6883572_0 1521187.JPIM01000020_gene236 3.452e-152 488.0 COG4177@1|root,COG4177@2|Bacteria,2G8ZK@200795|Chloroflexi,375J2@32061|Chloroflexia 32061|Chloroflexia E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SJTD3_k127_6883572_2 324602.Caur_3637 2.176e-139 449.0 COG0559@1|root,COG0559@2|Bacteria,2G9Z9@200795|Chloroflexi,37721@32061|Chloroflexia 32061|Chloroflexia E Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SJTD3_k127_6888301_0 234267.Acid_7589 1.653e-45 174.0 COG0457@1|root,COG0457@2|Bacteria 234267.Acid_7589|- S peptidyl-tyrosine sulfation - - - - - - - - - - - - - SJTD3_k127_6888301_1 720555.BATR1942_02760 1.182e-30 138.0 COG1404@1|root,COG1404@2|Bacteria,1TQ2M@1239|Firmicutes,4HBYC@91061|Bacilli,1ZPV5@1386|Bacillus 91061|Bacilli O Belongs to the peptidase S8 family aprE GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030193,GO:0030195,GO:0032101,GO:0032102,GO:0042730,GO:0043170,GO:0044238,GO:0048519,GO:0048583,GO:0048585,GO:0050789,GO:0050818,GO:0050819,GO:0050878,GO:0051239,GO:0051241,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070011,GO:0071704,GO:0080134,GO:0140096,GO:1900046,GO:1900047,GO:1901564,GO:1903034,GO:1903035 3.4.21.62 ko:K01342 ko02024,map02024 - - - ko00000,ko00001,ko01000,ko01002,ko03110 - - - Inhibitor_I9,Peptidase_S8,SLH SJTD3_k127_6891845_2 1128421.JAGA01000003_gene3253 1.455e-56 213.0 COG0726@1|root,COG0726@2|Bacteria,2NPV2@2323|unclassified Bacteria 2|Bacteria G Polysaccharide deacetylase - - 3.5.1.104 ko:K22278 - - - - ko00000,ko01000 - - - LysM,Polysacc_deac_1 SJTD3_k127_6891845_0 1380394.JADL01000002_gene1538 8.632e-108 360.0 COG0350@1|root,COG2169@1|root,COG0350@2|Bacteria,COG2169@2|Bacteria,1N2YQ@1224|Proteobacteria,2TQRX@28211|Alphaproteobacteria,2JPEG@204441|Rhodospirillales 204441|Rhodospirillales FL 6-O-methylguanine DNA methyltransferase, DNA binding domain - - 2.1.1.63 ko:K10778 - - - - ko00000,ko01000,ko03000,ko03400 - - - Ada_Zn_binding,DNA_binding_1,HTH_18,Methyltransf_1N SJTD3_k127_6891845_1 869210.Marky_0122 2.535e-66 233.0 COG0697@1|root,COG0697@2|Bacteria,1WJTG@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EG PFAM EamA-like transporter family - - - - - - - - - - - - EamA SJTD3_k127_6906541_0 1382306.JNIM01000001_gene4084 7.232e-131 441.0 COG4412@1|root,COG4412@2|Bacteria,2G622@200795|Chloroflexi 200795|Chloroflexi S Immune inhibitor A peptidase M6 - - - - - - - - - - - - Peptidase_M6 SJTD3_k127_6906541_1 479434.Sthe_0828 0.0005959 50.0 COG1286@1|root,COG1286@2|Bacteria,2G9FV@200795|Chloroflexi,27Y7E@189775|Thermomicrobia 189775|Thermomicrobia S Colicin V production protein - - - - - - - - - - - - Colicin_V SJTD3_k127_6907371_0 1382306.JNIM01000001_gene398 5.951e-89 307.0 COG0313@1|root,COG0313@2|Bacteria,2G5VQ@200795|Chloroflexi 200795|Chloroflexi H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI - 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase SJTD3_k127_6907371_1 485913.Krac_2072 3.078e-11 64.0 COG3173@1|root,COG3173@2|Bacteria,2G8S4@200795|Chloroflexi 200795|Chloroflexi S Ecdysteroid kinase - - - - - - - - - - - - APH SJTD3_k127_6917300_2 446470.Snas_5055 2.249e-85 291.0 COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4F0CB@85014|Glycomycetales 201174|Actinobacteria Q Fumarylacetoacetate (FAA) hydrolase family - - - - - - - - - - - - FAA_hydrolase SJTD3_k127_6917300_3 1242864.D187_002049 2.002e-48 195.0 COG0642@1|root,COG2203@1|root,COG2203@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,42RWK@68525|delta/epsilon subdivisions,2X4H3@28221|Deltaproteobacteria,2YZ04@29|Myxococcales 28221|Deltaproteobacteria T GAF domain - - - - - - - - - - - - GAF_2,HATPase_c,HisKA,PAS_4 SJTD3_k127_6917300_4 1379698.RBG1_1C00001G0503 2.474e-42 178.0 COG1807@1|root,COG1807@2|Bacteria,2NP0P@2323|unclassified Bacteria 2|Bacteria M Protein of unknown function (DUF2723) - - - - - - - - - - - - DUF2723,PMT_2 SJTD3_k127_6917300_0 525904.Tter_0432 2.883e-186 607.0 COG3408@1|root,COG3408@2|Bacteria,2NPYR@2323|unclassified Bacteria 2|Bacteria G Amylo-alpha-1,6-glucosidase - - - - - - - - - - - - GDE_C,GDE_N_bis SJTD3_k127_6917300_5 1121272.KB903261_gene5944 1.021e-27 116.0 2DZND@1|root,32VEJ@2|Bacteria,2IS1I@201174|Actinobacteria,4DG6X@85008|Micromonosporales 201174|Actinobacteria S NIPSNAP - - - - - - - - - - - - NIPSNAP SJTD3_k127_6917300_6 1267535.KB906767_gene1141 1.641e-27 123.0 COG0071@1|root,COG0071@2|Bacteria,3Y8BT@57723|Acidobacteria 57723|Acidobacteria O Hsp20/alpha crystallin family - - - ko:K13993 ko04141,map04141 - - - ko00000,ko00001,ko03110 - - - HSP20 SJTD3_k127_6917300_8 292.DM42_7041 7.087e-08 61.0 COG2823@1|root,COG2823@2|Bacteria,1QTYY@1224|Proteobacteria,2WGI6@28216|Betaproteobacteria,1KG4K@119060|Burkholderiaceae 28216|Betaproteobacteria S BON domain - - - - - - - - - - - - BON SJTD3_k127_6917300_7 765420.OSCT_1327 8.451e-21 100.0 COG0589@1|root,COG0589@2|Bacteria,2G91P@200795|Chloroflexi 200795|Chloroflexi T Universal stress protein family - - - - - - - - - - - - Usp SJTD3_k127_6917300_1 1128421.JAGA01000002_gene331 2.612e-134 437.0 COG0442@1|root,COG0442@2|Bacteria,2NNNH@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit SJTD3_k127_6919427_3 1123073.KB899242_gene1520 7.318e-20 94.0 COG1917@1|root,COG1917@2|Bacteria 2|Bacteria L Cupin 2, conserved barrel domain protein - - 4.4.1.3,5.3.3.19 ko:K16953,ko:K19547 ko00920,ko01130,map00920,map01130 M00787 R02574 RC00747,RC00748 ko00000,ko00001,ko00002,ko01000 - - - Asp_Arg_Hydrox,Cupin_1,Cupin_2 SJTD3_k127_6919427_5 1150399.AQYK01000002_gene3744 0.0003405 46.0 COG0383@1|root,COG0383@2|Bacteria,2I8W8@201174|Actinobacteria,4FSU4@85023|Microbacteriaceae 201174|Actinobacteria G Glycosyl hydrolases family 38 N-terminal domain - - - - - - - - - - - - Glyco_hydro_38,Glyco_hydro_38C SJTD3_k127_6919427_4 1123258.AQXZ01000012_gene2097 7.195e-06 53.0 COG3237@1|root,COG3237@2|Bacteria 2|Bacteria K CsbD-like - - - - - - - - - - - - CsbD SJTD3_k127_6919427_0 926569.ANT_22790 2.605e-177 566.0 COG1271@1|root,COG1271@2|Bacteria,2G5TR@200795|Chloroflexi 200795|Chloroflexi C PFAM cytochrome bd ubiquinol oxidase subunit I - - 1.10.3.14 ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_I SJTD3_k127_6919427_1 926569.ANT_22800 8.336e-149 477.0 COG1294@1|root,COG1294@2|Bacteria,2G67G@200795|Chloroflexi 200795|Chloroflexi C PFAM cytochrome bd ubiquinol oxidase subunit II - - 1.10.3.14 ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 M00153 R11325 RC00061 ko00000,ko00001,ko00002,ko01000 3.D.4.3 - - Cyt_bd_oxida_II SJTD3_k127_6919427_2 485913.Krac_2317 5.88e-87 299.0 COG4988@1|root,COG4988@2|Bacteria,2G7JB@200795|Chloroflexi 200795|Chloroflexi CO ABC transporter CydDC cysteine exporter (CydDC-E) family permease ATP-binding protein CydD - - - ko:K16013 ko02010,map02010 - - - ko00000,ko00001,ko02000 3.A.1.129 - - ABC_membrane,ABC_tran SJTD3_k127_6922425_1 765420.OSCT_1927 1.225e-25 116.0 COG2968@1|root,COG2968@2|Bacteria,2G6UC@200795|Chloroflexi,377CQ@32061|Chloroflexia 32061|Chloroflexia S Protein of unknown function (DUF541) - - - ko:K09807 - - - - ko00000 - - - SIMPL SJTD3_k127_6922425_0 35754.JNYJ01000019_gene80 1.209e-149 505.0 COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales 201174|Actinobacteria KT Transcriptional regulator - - - - - - - - - - - - AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12 SJTD3_k127_6922425_2 1207055.C100_18300 3.808e-05 56.0 COG3391@1|root,COG3391@2|Bacteria,1P862@1224|Proteobacteria,2TR6Z@28211|Alphaproteobacteria,2K2W8@204457|Sphingomonadales 204457|Sphingomonadales S Lactonase, 7-bladed beta-propeller - - - - - - - - - - - - Cytochrom_D1,Lactonase,PQQ_2 SJTD3_k127_6922757_2 515622.bpr_III185 0.0005692 43.0 COG5646@1|root,COG5646@2|Bacteria,1TRQ8@1239|Firmicutes,25B53@186801|Clostridia 186801|Clostridia S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801,DUF2200 SJTD3_k127_6922757_0 1183438.GKIL_3867 2.994e-27 119.0 COG1309@1|root,COG1309@2|Bacteria,1G0D9@1117|Cyanobacteria 1117|Cyanobacteria K PFAM Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_C_11,TetR_N SJTD3_k127_6922757_1 1068980.ARVW01000001_gene6240 1.03e-08 60.0 COG3794@1|root,COG3794@2|Bacteria,2H73G@201174|Actinobacteria,4E2Z7@85010|Pseudonocardiales 201174|Actinobacteria C Copper binding proteins, plastocyanin/azurin family - - - - - - - - - - - - Copper-bind,Cupredoxin_1 SJTD3_k127_6932597_4 867903.ThesuDRAFT_02179 8.321e-42 167.0 COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3WDJP@538999|Clostridiales incertae sedis 186801|Clostridia S Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4,Peptidase_S9 SJTD3_k127_6932597_3 189425.PGRAT_11095 2.295e-47 173.0 COG5646@1|root,COG5646@2|Bacteria,1V6QB@1239|Firmicutes,4HINV@91061|Bacilli,26YRN@186822|Paenibacillaceae 91061|Bacilli S Domain of unknown function (DU1801) - - - - - - - - - - - - DUF1801 SJTD3_k127_6932597_1 1033743.CAES01000103_gene3523 2.855e-98 340.0 COG1680@1|root,COG1680@2|Bacteria,1UZZ5@1239|Firmicutes,4HA1I@91061|Bacilli,26XEG@186822|Paenibacillaceae 91061|Bacilli V Beta-lactamase - - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - Beta-lactamase SJTD3_k127_6932597_0 1122237.AUGQ01000004_gene1605 2.672e-107 366.0 COG2252@1|root,COG2252@2|Bacteria,2GKYD@201174|Actinobacteria,4FN8D@85023|Microbacteriaceae 201174|Actinobacteria S Permease family pbuG - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease SJTD3_k127_6932597_2 867845.KI911784_gene1720 5.693e-48 181.0 COG1185@1|root,COG1185@2|Bacteria,2G5TS@200795|Chloroflexi,374W6@32061|Chloroflexia 32061|Chloroflexia J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp - 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 SJTD3_k127_6932691_1 1128421.JAGA01000003_gene3707 4.517e-91 307.0 COG0740@1|root,COG0740@2|Bacteria,2NNPA@2323|unclassified Bacteria 2|Bacteria O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP - 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease SJTD3_k127_6932691_4 98439.AJLL01000098_gene1988 0.000595 50.0 2E16S@1|root,32WMI@2|Bacteria,1G8JJ@1117|Cyanobacteria,1JKYG@1189|Stigonemataceae 1117|Cyanobacteria - - - - - - - - - - - - - - - SJTD3_k127_6932691_0 1382306.JNIM01000001_gene601 6.905e-132 434.0 COG1524@1|root,COG1524@2|Bacteria,2G5RJ@200795|Chloroflexi 200795|Chloroflexi S type I phosphodiesterase nucleotide pyrophosphatase - - - - - - - - - - - - Phosphodiest SJTD3_k127_6932691_2 525904.Tter_1430 2.342e-72 263.0 COG0544@1|root,COG0544@2|Bacteria,2NPBN@2323|unclassified Bacteria 2|Bacteria D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N SJTD3_k127_6938246_1 1116375.VEJY3_21596 6.85e-47 179.0 COG4932@1|root,COG4932@2|Bacteria,1R944@1224|Proteobacteria,1S165@1236|Gammaproteobacteria,1Y09R@135623|Vibrionales 135623|Vibrionales M domain protein - - - - - - - - - - - - - SJTD3_k127_6938246_0 1278073.MYSTI_03563 1.533e-104 373.0 COG0642@1|root,COG2202@1|root,COG5000@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,COG5000@2|Bacteria,1Q394@1224|Proteobacteria,4390D@68525|delta/epsilon subdivisions,2X45F@28221|Deltaproteobacteria,2YYAY@29|Myxococcales 28221|Deltaproteobacteria T PAS fold - - - - - - - - - - - - HATPase_c,HisKA SJTD3_k127_6938246_2 1120950.KB892764_gene5624 1.22e-22 100.0 COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4DQZM@85009|Propionibacteriales 201174|Actinobacteria T helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,Response_reg SJTD3_k127_6943282_0 316274.Haur_3433 3.656e-50 190.0 COG1595@1|root,COG1595@2|Bacteria,2G6T5@200795|Chloroflexi,375JF@32061|Chloroflexia 32061|Chloroflexia K PFAM sigma-70 region 2 domain protein - - - ko:K03088 - - - - ko00000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 SJTD3_k127_6943282_2 1033810.HLPCO_002713 1.416e-12 74.0 COG5652@1|root,COG5652@2|Bacteria,2NRYD@2323|unclassified Bacteria 2|Bacteria S VanZ like family - - - - - - - - - - - - VanZ SJTD3_k127_6943282_3 1123052.AUDF01000016_gene851 7.371e-05 54.0 COG1215@1|root,COG1215@2|Bacteria,2I8SD@201174|Actinobacteria,4FQXR@85023|Microbacteriaceae 201174|Actinobacteria M Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glycos_transf_2 SJTD3_k127_6943282_1 324602.Caur_0535 1.458e-27 124.0 COG0392@1|root,COG0392@2|Bacteria,2G5KF@200795|Chloroflexi,374YY@32061|Chloroflexia 32061|Chloroflexia S PFAM conserved - - - ko:K07027 - - - - ko00000,ko02000 4.D.2 - - LPG_synthase_TM SJTD3_k127_6957540_3 357808.RoseRS_0779 9.095e-27 130.0 COG1807@1|root,COG1807@2|Bacteria,2G8TF@200795|Chloroflexi,377RQ@32061|Chloroflexia 32061|Chloroflexia M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_6957540_1 1382356.JQMP01000001_gene1008 1.349e-67 264.0 29X1J@1|root,30IPW@2|Bacteria,2GBCF@200795|Chloroflexi,27YRV@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - SJTD3_k127_6957540_2 879212.DespoDRAFT_01898 1.077e-39 162.0 COG0500@1|root,COG2226@2|Bacteria,1QYW6@1224|Proteobacteria,43DBX@68525|delta/epsilon subdivisions,2X8HY@28221|Deltaproteobacteria 28221|Deltaproteobacteria H Methionine biosynthesis protein MetW - - - - - - - - - - - - - SJTD3_k127_6957540_0 479434.Sthe_3254 2.455e-71 269.0 COG1287@1|root,COG1287@2|Bacteria,2G75T@200795|Chloroflexi,27XID@189775|Thermomicrobia 189775|Thermomicrobia S Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_6957540_4 330214.NIDE1420 5.066e-09 61.0 COG3391@1|root,COG3391@2|Bacteria 2|Bacteria CO amine dehydrogenase activity - - - - - - - - - - - - DUF5128,NHL,PA14 SJTD3_k127_6959125_3 420324.KI911948_gene9176 3.441e-62 228.0 COG1619@1|root,COG1619@2|Bacteria,1MWIY@1224|Proteobacteria,2U2WH@28211|Alphaproteobacteria 28211|Alphaproteobacteria V proteins, homologs of microcin C7 resistance protein MccF mccF - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 SJTD3_k127_6959125_2 926550.CLDAP_09500 6.676e-65 226.0 COG2318@1|root,COG2318@2|Bacteria,2G91B@200795|Chloroflexi 200795|Chloroflexi S Protein of unknown function (DUF664) - - - - - - - - - - - - DinB_2 SJTD3_k127_6959125_1 323850.Shew_3239 3.818e-143 473.0 COG2373@1|root,COG3055@1|root,COG3386@1|root,COG2373@2|Bacteria,COG3055@2|Bacteria,COG3386@2|Bacteria,1N85X@1224|Proteobacteria,1T3ZR@1236|Gammaproteobacteria,2QEVC@267890|Shewanellaceae 1224|Proteobacteria M PFAM Na-Ca exchanger integrin-beta4 - - - - - - - - - - - - - SJTD3_k127_6959125_0 1128421.JAGA01000004_gene2674 4.938e-301 929.0 COG0366@1|root,COG0366@2|Bacteria,2NQND@2323|unclassified Bacteria 2|Bacteria G Maltogenic Amylase, C-terminal domain treS - 3.2.1.1,5.4.99.16 ko:K05343 ko00500,ko01100,map00500,map01100 - R01557,R02108,R02112,R11262 RC01816 ko00000,ko00001,ko01000 - GH13 - APH,Alpha-amylase,Malt_amylase_C SJTD3_k127_6959125_4 118166.JH976537_gene324 3.742e-34 145.0 COG3187@1|root,COG3187@2|Bacteria,1GA7U@1117|Cyanobacteria 1117|Cyanobacteria O META domain - - - ko:K03929 - - - - ko00000,ko01000 - CE10 - META SJTD3_k127_6959617_2 935863.AWZR01000014_gene2990 7.631e-29 118.0 2E9PS@1|root,333W4@2|Bacteria,1PAX9@1224|Proteobacteria,1SRZ9@1236|Gammaproteobacteria,1XBIE@135614|Xanthomonadales 135614|Xanthomonadales - - - - - - - - - - - - - - - SJTD3_k127_6959617_0 264732.Moth_2026 8.893e-168 534.0 COG4952@1|root,COG4952@2|Bacteria,1UD8H@1239|Firmicutes,24HDU@186801|Clostridia,42FRC@68295|Thermoanaerobacterales 186801|Clostridia G Xylose isomerase-like TIM barrel - - 5.3.1.5 ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 - R00878,R01432 RC00376,RC00516 ko00000,ko00001,ko01000 - - - AP_endonuc_2 SJTD3_k127_6959617_1 1128421.JAGA01000002_gene1088 1.855e-56 203.0 COG1070@1|root,COG1070@2|Bacteria,2NQBU@2323|unclassified Bacteria 2|Bacteria G FGGY family of carbohydrate kinases, N-terminal domain xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU17610 FGGY_C,FGGY_N SJTD3_k127_6961857_0 319225.Plut_0242 2.482e-59 222.0 COG1215@1|root,COG1215@2|Bacteria,1FDR6@1090|Chlorobi 1090|Chlorobi M PFAM glycosyl transferase family 2 - - - ko:K14597 ko00906,map00906 - R07544,R07546 RC00262 ko00000,ko00001 - - - Glyco_tranf_2_3,Glycos_transf_2 SJTD3_k127_6962334_3 1183438.GKIL_2176 4.185e-10 74.0 COG1372@1|root,COG4409@1|root,COG1372@2|Bacteria,COG4409@2|Bacteria 2|Bacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - ASH,BNR_2,Phage_Mu_F,RHS_repeat SJTD3_k127_6962334_1 1124780.ANNU01000038_gene185 1.024e-21 112.0 COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,4NG09@976|Bacteroidetes,47NP4@768503|Cytophagia 976|Bacteroidetes S Fungalysin metallopeptidase (M36) - - - - - - - - - - - - FTP,PA,PKD,Peptidase_M36 SJTD3_k127_6962334_0 525904.Tter_2777 6.581e-32 146.0 COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,2NPM4@2323|unclassified Bacteria 2|Bacteria G Galactose oxidase, central domain - - - - - - - - - - - - Big_5,CBM_35,CBM_6,GSDH,Kelch_1,Kelch_6 SJTD3_k127_6962334_2 105559.Nwat_0328 4.713e-14 87.0 COG3055@1|root,COG3055@2|Bacteria,1QSB4@1224|Proteobacteria,1S2EP@1236|Gammaproteobacteria,1WZIK@135613|Chromatiales 135613|Chromatiales S Galactose oxidase, central domain - - - - - - - - - - - - Kelch_6 SJTD3_k127_6968296_0 479434.Sthe_1174 2.198e-114 393.0 COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,27Y0P@189775|Thermomicrobia 189775|Thermomicrobia M Uncharacterized membrane protein (DUF2298) - - - - - - - - - - - - DUF2298,PMT_2 SJTD3_k127_6972959_3 1128421.JAGA01000002_gene1674 4.935e-09 59.0 COG1070@1|root,COG1070@2|Bacteria,2NQHC@2323|unclassified Bacteria 2|Bacteria G FGGY family of carbohydrate kinases, N-terminal domain - - 2.7.1.12 ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 - R01737 RC00002,RC00017 ko00000,ko00001,ko01000 - - - FGGY_C,FGGY_N SJTD3_k127_6972959_1 383372.Rcas_0946 1.673e-152 494.0 COG0448@1|root,COG0448@2|Bacteria,2G66Q@200795|Chloroflexi,374V0@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase SJTD3_k127_6972959_0 326427.Cagg_0428 1.746e-211 662.0 COG0297@1|root,COG0297@2|Bacteria 2|Bacteria G glycogen (starch) synthase activity glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 ko:K16148 ko00500,ko01100,map00500,map01100 - R02421,R11530 RC00005,RC00049,RC02748 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_6972959_2 65393.PCC7424_4132 3.505e-121 391.0 COG0033@1|root,COG0033@2|Bacteria,1G4TU@1117|Cyanobacteria,3KJFW@43988|Cyanothece 1117|Cyanobacteria G phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - iJN678.pgm PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV SJTD3_k127_6983105_0 479434.Sthe_0414 4.715e-122 406.0 COG0358@1|root,COG0358@2|Bacteria,2G65X@200795|Chloroflexi,27XKY@189775|Thermomicrobia 189775|Thermomicrobia L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB_bind,Toprim_4,Toprim_N,zf-CHC2 SJTD3_k127_6983105_1 357808.RoseRS_0289 5.374e-73 254.0 COG0232@1|root,COG0232@2|Bacteria,2G5VZ@200795|Chloroflexi,3754T@32061|Chloroflexia 32061|Chloroflexia F PFAM metal-dependent phosphohydrolase, HD sub domain - - 3.1.5.1 ko:K01129 ko00230,map00230 - R01856 RC00017 ko00000,ko00001,ko01000 - - - HD,HD_assoc SJTD3_k127_6983346_3 324602.Caur_0718 9.703e-17 86.0 COG1476@1|root,COG3903@1|root,COG1476@2|Bacteria,COG3903@2|Bacteria,2G64X@200795|Chloroflexi,376A5@32061|Chloroflexia 32061|Chloroflexia K PFAM helix-turn-helix domain protein - - - - - - - - - - - - HTH_3,HTH_31,NB-ARC,TPR_12 SJTD3_k127_6983346_2 370438.PTH_0557 7.842e-63 231.0 COG0644@1|root,COG0644@2|Bacteria,1TRTQ@1239|Firmicutes,24E1W@186801|Clostridia,261F2@186807|Peptococcaceae 186801|Clostridia C TIGRFAM geranylgeranyl reductase family - - - - - - - - - - - - FAD_binding_3,Lycopene_cycl SJTD3_k127_6983346_1 267608.RSp0174 2.696e-68 241.0 COG0500@1|root,COG2226@2|Bacteria,1R6ZI@1224|Proteobacteria,2VTR5@28216|Betaproteobacteria,1K3MW@119060|Burkholderiaceae 28216|Betaproteobacteria Q Mycolic acid cyclopropane synthetase - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_6983346_0 1267535.KB906767_gene4480 6.553e-73 251.0 COG4430@1|root,COG4430@2|Bacteria,3Y5HF@57723|Acidobacteria,2JMZY@204432|Acidobacteriia 204432|Acidobacteriia S Bacteriocin-protection, YdeI or OmpD-Associated - - - - - - - - - - - - OmdA SJTD3_k127_698737_0 370438.PTH_1032 8.647e-117 383.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,260AS@186807|Peptococcaceae 186801|Clostridia F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt - 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT SJTD3_k127_698737_1 1382306.JNIM01000001_gene3401 2.489e-111 376.0 COG1600@1|root,COG1600@2|Bacteria,2G6A0@200795|Chloroflexi 200795|Chloroflexi C 4Fe-4S double cluster binding domain - - 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Dehalogenase,Fer4_16,HEAT_2 SJTD3_k127_698737_3 906968.Trebr_0483 2.116e-93 315.0 COG1351@1|root,COG1351@2|Bacteria,2J68R@203691|Spirochaetes 203691|Spirochaetes F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant thyX - 2.1.1.148 ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 - R06613 RC00022,RC00332 ko00000,ko00001,ko01000 - - - Thy1 SJTD3_k127_698737_4 179408.Osc7112_4248 7.822e-21 96.0 COG0745@1|root,COG0745@2|Bacteria,1G5PY@1117|Cyanobacteria,1HB2D@1150|Oscillatoriales 1117|Cyanobacteria KT Response regulator receiver domain - - - ko:K02658 ko02020,ko02025,map02020,map02025 M00507 - - ko00000,ko00001,ko00002,ko02022,ko02035,ko02044 - - - Response_reg SJTD3_k127_698737_2 485913.Krac_12092 1.725e-95 314.0 COG4799@1|root,COG4799@2|Bacteria,2G5IX@200795|Chloroflexi 200795|Chloroflexi I PFAM carboxyl transferase - - 2.1.3.15,6.4.1.3 ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 M00373,M00741 R01859 RC00097,RC00609 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans SJTD3_k127_6996408_0 485913.Krac_8789 1.259e-84 286.0 COG1232@1|root,COG1232@2|Bacteria,2G5VN@200795|Chloroflexi 200795|Chloroflexi H PFAM amine oxidase - - - - - - - - - - - - Amino_oxidase SJTD3_k127_6996408_1 1894.JOER01000022_gene3916 2.323e-20 97.0 COG0586@1|root,COG0586@2|Bacteria,2IE8G@201174|Actinobacteria 201174|Actinobacteria I SNARE associated Golgi protein - - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2,SNARE_assoc SJTD3_k127_6996408_2 309801.trd_A0256 1.39e-05 54.0 COG1316@1|root,COG1316@2|Bacteria,2G6PZ@200795|Chloroflexi,27XRZ@189775|Thermomicrobia 200795|Chloroflexi K cell envelope-related transcriptional attenuator - - - - - - - - - - - - LytR_C,LytR_cpsA_psr SJTD3_k127_6999418_4 926550.CLDAP_10360 7.144e-14 72.0 COG0457@1|root,COG3307@1|root,COG0457@2|Bacteria,COG3307@2|Bacteria,2G81B@200795|Chloroflexi 200795|Chloroflexi M -O-antigen - - - - - - - - - - - - TPR_16,Wzy_C SJTD3_k127_6999418_0 926550.CLDAP_00350 1.223e-156 514.0 COG0497@1|root,COG0497@2|Bacteria,2G5V1@200795|Chloroflexi 200795|Chloroflexi L May be involved in recombinational repair of damaged DNA recN - - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N SJTD3_k127_6999418_3 525904.Tter_0346 6.31e-14 80.0 COG0762@1|root,COG0762@2|Bacteria,2NRP0@2323|unclassified Bacteria 2|Bacteria S YGGT family - - - - - - - - - - - - YGGT SJTD3_k127_6999418_1 309801.trd_1822 6.251e-34 150.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_7002511_1 258594.RPA4277 3.364e-62 220.0 COG4335@1|root,COG4335@2|Bacteria,1NWY5@1224|Proteobacteria 1224|Proteobacteria L DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation SJTD3_k127_7002511_0 1380390.JIAT01000010_gene4928 2.048e-86 307.0 COG0569@1|root,COG0569@2|Bacteria,2I74Z@201174|Actinobacteria 201174|Actinobacteria P Ion channel - - - - - - - - - - - - Ion_trans_2,TrkA_N SJTD3_k127_701340_1 1045855.DSC_12680 3.285e-15 78.0 COG0154@1|root,COG0154@2|Bacteria,1MUVQ@1224|Proteobacteria,1RP7E@1236|Gammaproteobacteria,1X4K6@135614|Xanthomonadales 135614|Xanthomonadales J Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia gatAX - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase,Lipocalin_5 SJTD3_k127_701340_5 1122137.AQXF01000001_gene3304 4.961e-06 57.0 COG2267@1|root,COG2267@2|Bacteria,1MYEX@1224|Proteobacteria,2U5YK@28211|Alphaproteobacteria 28211|Alphaproteobacteria I Serine aminopeptidase, S33 - - 3.4.11.5 ko:K01259 ko00330,map00330 - R00135 - ko00000,ko00001,ko01000,ko01002 - - - Abhydrolase_1 SJTD3_k127_701340_3 293826.Amet_3276 3.555e-09 64.0 2EMRE@1|root,33FDW@2|Bacteria,1VNPH@1239|Firmicutes,24UTS@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - SJTD3_k127_701340_2 665571.STHERM_c14960 3.394e-13 77.0 28WAT@1|root,2ZIB9@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_701340_0 867903.ThesuDRAFT_01767 4.409e-102 338.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3WD8H@538999|Clostridiales incertae sedis 186801|Clostridia K Transcriptional regulatory protein, C terminal - - - ko:K02483,ko:K07669 ko02020,map02020 M00460 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SJTD3_k127_701340_4 937777.Deipe_0703 1.553e-06 52.0 COG5002@1|root,COG5002@2|Bacteria,1WMAK@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - - - - - - - - - - HAMP,HATPase_c,HisKA SJTD3_k127_7021883_1 383372.Rcas_3047 1.402e-36 146.0 COG1716@1|root,COG1716@2|Bacteria,2G8U3@200795|Chloroflexi,375MN@32061|Chloroflexia 32061|Chloroflexia T PFAM Forkhead-associated protein - - - - - - - - - - - - DZR,FHA SJTD3_k127_7021883_2 479434.Sthe_1540 1.067e-30 130.0 2E8MZ@1|root,332ZD@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_7021883_0 765420.OSCT_0378 1.202e-116 389.0 COG2304@1|root,COG2304@2|Bacteria,2G82P@200795|Chloroflexi,374S6@32061|Chloroflexia 32061|Chloroflexia S PFAM von Willebrand factor type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - VWA SJTD3_k127_7021883_3 1002339.HMPREF9373_1718 1.482e-05 52.0 COG5283@1|root,COG5283@2|Bacteria,1QZ8Y@1224|Proteobacteria,1S2FG@1236|Gammaproteobacteria,3NTQH@468|Moraxellaceae 1236|Gammaproteobacteria M lytic transglycosylase activity - - - - - - - - - - - - - SJTD3_k127_7024464_4 582899.Hden_1818 1.307e-11 72.0 COG1610@1|root,COG1610@2|Bacteria,1RGZS@1224|Proteobacteria,2U7DJ@28211|Alphaproteobacteria,3N75W@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria S Yqey-like protein MA20_04985 - - ko:K09117 - - - - ko00000 - - - YqeY SJTD3_k127_7024464_3 525904.Tter_1056 8.476e-19 87.0 COG0828@1|root,COG0828@2|Bacteria,2NQ1U@2323|unclassified Bacteria 2|Bacteria J Ribosomal protein S21 rpsU GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 SJTD3_k127_7024464_0 1394178.AWOO02000027_gene5296 1.537e-103 343.0 COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4EHV2@85012|Streptosporangiales 201174|Actinobacteria E ATPases associated with a variety of cellular activities atrC - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran SJTD3_k127_7024464_1 1502724.FF80_03159 9.956e-57 209.0 COG0765@1|root,COG0765@2|Bacteria,1QN80@1224|Proteobacteria,2V8C0@28211|Alphaproteobacteria,3N8TB@45401|Hyphomicrobiaceae 28211|Alphaproteobacteria U Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 SJTD3_k127_7024464_2 1169161.KB897729_gene1237 3.966e-52 199.0 COG0834@1|root,COG0834@2|Bacteria,2GJQW@201174|Actinobacteria 201174|Actinobacteria ET Belongs to the bacterial solute-binding protein 3 family atrA - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 SJTD3_k127_7033275_1 1385935.N836_21905 7.32e-05 56.0 COG4585@1|root,COG4585@2|Bacteria 2|Bacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HATPase_c_2,HisKA_3 SJTD3_k127_7033275_0 1122138.AQUZ01000014_gene7126 7.258e-52 209.0 COG4585@1|root,COG4585@2|Bacteria,2HDZV@201174|Actinobacteria 201174|Actinobacteria T Histidine kinase - - - - - - - - - - - - HATPase_c,HisKA_3 SJTD3_k127_70403_1 667014.Thein_1524 4.642e-150 484.0 COG0438@1|root,COG0438@2|Bacteria,2GHNP@200940|Thermodesulfobacteria 200940|Thermodesulfobacteria M Glycosyltransferase Family 4 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_70403_0 525904.Tter_0432 6.442e-189 614.0 COG3408@1|root,COG3408@2|Bacteria,2NPYR@2323|unclassified Bacteria 2|Bacteria G Amylo-alpha-1,6-glucosidase - - - - - - - - - - - - GDE_C,GDE_N_bis SJTD3_k127_7041421_0 1125863.JAFN01000001_gene1578 5.374e-155 495.0 COG0008@1|root,COG0008@2|Bacteria,1MUC8@1224|Proteobacteria,42MAX@68525|delta/epsilon subdivisions,2WJ5B@28221|Deltaproteobacteria 28221|Deltaproteobacteria J PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic glnS - 6.1.1.18 ko:K01886 ko00970,ko01100,map00970,map01100 M00359,M00360 R03652 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - GatB_Yqey,tRNA-synt_1c,tRNA-synt_1c_C SJTD3_k127_7041421_1 35754.JNYJ01000006_gene5300 0.000369 46.0 COG2706@1|root,COG2706@2|Bacteria,2I6SW@201174|Actinobacteria,4DJEB@85008|Micromonosporales 201174|Actinobacteria G 6-phosphogluconolactonase activity - - - - - - - - - - - - Lactonase SJTD3_k127_7042110_1 1121396.KB893057_gene2478 2.63e-05 52.0 COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,1MVZZ@1224|Proteobacteria,42W78@68525|delta/epsilon subdivisions,2WRWC@28221|Deltaproteobacteria 28221|Deltaproteobacteria K Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' - - - ko:K03556 - - - - ko00000,ko03000 - - - BTAD,GerE SJTD3_k127_7042110_0 696281.Desru_0014 2.175e-86 291.0 COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,25B08@186801|Clostridia,261WI@186807|Peptococcaceae 186801|Clostridia E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine - - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP SJTD3_k127_7048836_1 349161.Dred_2547 9.6e-16 80.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,260H4@186807|Peptococcaceae 186801|Clostridia M Involved in formation and maintenance of cell shape mreC - - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC SJTD3_k127_7048836_2 309801.trd_1928 3.333e-06 58.0 COG2891@1|root,COG2891@2|Bacteria,2GBC9@200795|Chloroflexi,27YRC@189775|Thermomicrobia 189775|Thermomicrobia M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins - - - - - - - - - - - - MreD SJTD3_k127_7048836_0 479434.Sthe_2013 3.949e-28 128.0 COG0768@1|root,COG0768@2|Bacteria,2G64Z@200795|Chloroflexi,27Y4X@189775|Thermomicrobia 189775|Thermomicrobia M Penicillin-binding Protein dimerisation domain - - 3.4.16.4 ko:K05515 ko00550,ko01501,map00550,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase SJTD3_k127_7051909_0 1128421.JAGA01000002_gene1001 9.167e-50 196.0 COG1807@1|root,COG1807@2|Bacteria,2NS23@2323|unclassified Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - - - - - - - - - - Glyco_transf_22,PMT,PMT_2 SJTD3_k127_7051909_1 1382356.JQMP01000004_gene46 1.749e-14 75.0 COG2835@1|root,COG2835@2|Bacteria,2GBCC@200795|Chloroflexi,27YRI@189775|Thermomicrobia 189775|Thermomicrobia S Trm112p-like protein - - - ko:K09791 - - - - ko00000 - - - Trm112p SJTD3_k127_7059743_0 1122138.AQUZ01000019_gene8174 0.0 1077.0 COG0737@1|root,COG1524@1|root,COG3379@1|root,COG0737@2|Bacteria,COG1524@2|Bacteria,COG3379@2|Bacteria,2HFJ5@201174|Actinobacteria,4DVDK@85009|Propionibacteriales 201174|Actinobacteria F 5'-nucleotidase, C-terminal domain - - - - - - - - - - - - 5_nucleotid_C SJTD3_k127_7059743_4 1347368.HG964403_gene3974 7.914e-24 116.0 COG4632@1|root,COG4632@2|Bacteria,1UWXQ@1239|Firmicutes,4HWZ4@91061|Bacilli,1ZNWY@1386|Bacillus 91061|Bacilli G S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_7059743_1 1382306.JNIM01000001_gene2786 3.949e-236 737.0 COG0719@1|root,COG0719@2|Bacteria,2G5TI@200795|Chloroflexi 200795|Chloroflexi O TIGRFAM FeS assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 SJTD3_k127_7059743_2 1382306.JNIM01000001_gene894 9.776e-138 448.0 COG0438@1|root,COG0438@2|Bacteria,2G683@200795|Chloroflexi 200795|Chloroflexi M PFAM glycosyl transferase group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_7059743_5 926550.CLDAP_39150 6.173e-13 79.0 COG3944@1|root,COG3944@2|Bacteria,2G7A7@200795|Chloroflexi 200795|Chloroflexi M Lipopolysaccharide biosynthesis protein - - - - - - - - - - - - Wzz SJTD3_k127_7059743_6 998674.ATTE01000001_gene2799 6.702e-05 53.0 COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,1RNB0@1236|Gammaproteobacteria,461WI@72273|Thiotrichales 72273|Thiotrichales D G-rich domain on putative tyrosine kinase - - - - - - - - - - - - CbiA,GNVR,Wzz SJTD3_k127_7059743_3 383372.Rcas_3668 1.915e-57 205.0 COG0489@1|root,COG0489@2|Bacteria,2G5WM@200795|Chloroflexi,375EN@32061|Chloroflexia 32061|Chloroflexia D TIGRFAM capsular exopolysaccharide family - - 2.7.10.2 ko:K08253 - - - - ko00000,ko01000 - - - CbiA,ParA SJTD3_k127_7062488_0 316274.Haur_0504 3.935e-53 196.0 COG2353@1|root,COG2353@2|Bacteria,2G8UF@200795|Chloroflexi,3775M@32061|Chloroflexia 32061|Chloroflexia S Belongs to the UPF0312 family - - - - - - - - - - - - YceI SJTD3_k127_7062488_1 765420.OSCT_0745 9.069e-46 182.0 COG2304@1|root,COG2304@2|Bacteria 2|Bacteria IU oxidoreductase activity - - - - - - - - - - - - CarboxypepD_reg,CsgG,SLH,VWA,VWA_2 SJTD3_k127_7065251_2 1128421.JAGA01000001_gene2083 1.661e-34 141.0 COG1475@1|root,COG1475@2|Bacteria,2NS1X@2323|unclassified Bacteria 2|Bacteria K DNA binding - - - - - - - - - - - - DUF4032,ParBc SJTD3_k127_7065251_1 316274.Haur_4209 2.471e-73 258.0 COG1030@1|root,COG1030@2|Bacteria,2G8HI@200795|Chloroflexi,37796@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - TspO_MBR SJTD3_k127_7065251_0 196162.Noca_1500 1.038e-82 282.0 COG2013@1|root,COG2013@2|Bacteria,2I9XC@201174|Actinobacteria,4DV9Q@85009|Propionibacteriales 201174|Actinobacteria S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 SJTD3_k127_7065431_2 926564.KI911764_gene4523 2.014e-15 86.0 2BB39@1|root,324JH@2|Bacteria,2H9FU@201174|Actinobacteria 201174|Actinobacteria S Phosphotransferase enzyme family - - - - - - - - - - - - APH SJTD3_k127_7065431_0 525904.Tter_0089 6.772e-291 918.0 COG0013@1|root,COG0013@2|Bacteria,2NNYC@2323|unclassified Bacteria 2|Bacteria J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 DHHA1,tRNA-synt_2c,tRNA_SAD SJTD3_k127_7065431_1 37919.EP51_03085 3.41e-38 144.0 2DBX9@1|root,2ZBN9@2|Bacteria,2I98J@201174|Actinobacteria,4G1XB@85025|Nocardiaceae 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_7066699_1 861299.J421_3786 4.933e-111 369.0 COG0282@1|root,COG0282@2|Bacteria,1ZT9P@142182|Gemmatimonadetes 142182|Gemmatimonadetes C Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase SJTD3_k127_7066699_0 485913.Krac_4958 0.0 1204.0 COG3957@1|root,COG3957@2|Bacteria 2|Bacteria G D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase xfp - 4.1.2.22,4.1.2.9 ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 - R00761,R01621 RC00032,RC00226 ko00000,ko00001,ko01000 - - - XFP,XFP_C,XFP_N SJTD3_k127_7066699_2 335543.Sfum_3731 1.333e-19 93.0 COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,42U37@68525|delta/epsilon subdivisions,2WQ9M@28221|Deltaproteobacteria,2MRZA@213462|Syntrophobacterales 28221|Deltaproteobacteria S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 SJTD3_k127_7067745_0 797299.HALLA_03760 2.232e-74 263.0 COG0697@1|root,arCOG00271@2157|Archaea,2XY2J@28890|Euryarchaeota,23Z1Z@183963|Halobacteria 183963|Halobacteria G EamA-like transporter family - - - - - - - - - - - - EamA SJTD3_k127_7080199_2 941824.TCEL_01462 1.131e-33 134.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,36JT8@31979|Clostridiaceae 186801|Clostridia S acyl-CoA thioester hydrolase, YbgC YbaW family FcbC - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 SJTD3_k127_7080199_0 671143.DAMO_2906 8.578e-153 494.0 COG2132@1|root,COG2132@2|Bacteria 2|Bacteria Q Multicopper oxidase - - 1.16.3.3,1.7.2.1 ko:K00368,ko:K22348 ko00910,ko01120,map00910,map01120 M00529 R00783,R00785 RC00086 ko00000,ko00001,ko00002,ko01000 - - - Copper-bind,Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3,SdrD_B,TIG,fn3_3 SJTD3_k127_7080199_3 9031.ENSGALP00000041104 6.149e-12 73.0 KOG0568@1|root,KOG0568@2759|Eukaryota,38G8X@33154|Opisthokonta,3BGHV@33208|Metazoa,3CZQ5@33213|Bilateria,489VI@7711|Chordata,48WBK@7742|Vertebrata,4GJY7@8782|Aves 33208|Metazoa O homolog subfamily C member 28 DNAJC28 GO:0000301,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0006810,GO:0006890,GO:0006891,GO:0006996,GO:0007030,GO:0008150,GO:0009987,GO:0010256,GO:0012505,GO:0016043,GO:0016192,GO:0017119,GO:0022607,GO:0032991,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0048193,GO:0048213,GO:0051179,GO:0051234,GO:0065003,GO:0071840,GO:0099023 - ko:K19373 - - - - ko00000,ko03110 - - - DUF1992,DnaJ SJTD3_k127_7080199_1 1382356.JQMP01000003_gene1531 7.985e-37 146.0 COG2340@1|root,COG5479@1|root,COG2340@2|Bacteria,COG5479@2|Bacteria,2GBCS@200795|Chloroflexi,27YT2@189775|Thermomicrobia 189775|Thermomicrobia M Cysteine-rich secretory protein family - - - - - - - - - - - - CAP SJTD3_k127_7091435_5 1382356.JQMP01000003_gene2027 6.315e-41 163.0 COG0412@1|root,COG0412@2|Bacteria,2G9WC@200795|Chloroflexi,27Z94@189775|Thermomicrobia 189775|Thermomicrobia Q Dienelactone hydrolase family - - 3.1.1.45 ko:K01061 ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130 - R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222 RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686 ko00000,ko00001,ko01000 - - - DLH SJTD3_k127_7091435_4 1262914.BN533_00304 4.523e-48 182.0 COG1647@1|root,COG1647@2|Bacteria,1TQ7X@1239|Firmicutes,4H3ZP@909932|Negativicutes 909932|Negativicutes S Serine aminopeptidase, S33 est - 3.1.1.1 ko:K03928 - - - - ko00000,ko01000 - - - Hydrolase_4 SJTD3_k127_7091435_2 927677.ALVU02000001_gene2767 1.203e-77 276.0 COG3437@1|root,COG5002@1|root,COG3437@2|Bacteria,COG5002@2|Bacteria,1GHEK@1117|Cyanobacteria,1H69U@1142|Synechocystis 1117|Cyanobacteria T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HisKA,PAS,PAS_4,Response_reg SJTD3_k127_7091435_3 63737.Npun_F3540 4.219e-57 206.0 COG2201@1|root,COG2201@2|Bacteria,1G6B8@1117|Cyanobacteria,1HNNM@1161|Nostocales 1117|Cyanobacteria NT CheB methylesterase - - 3.1.1.61,3.5.1.44 ko:K03412 ko02020,ko02030,map02020,map02030 M00506 - - ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 - - - CheB_methylest SJTD3_k127_7091435_1 1487953.JMKF01000005_gene617 2.07e-118 387.0 COG1352@1|root,COG1352@2|Bacteria,1G1E5@1117|Cyanobacteria,1H94K@1150|Oscillatoriales 1117|Cyanobacteria NT PFAM CheR methyltransferase, SAM binding domain - - 2.1.1.80 ko:K00575 ko02020,ko02030,map02020,map02030 - - - ko00000,ko00001,ko01000,ko02035 - - - CheR,CheR_N SJTD3_k127_7091435_0 756067.MicvaDRAFT_0974 0.0 2696.0 COG0642@1|root,COG0745@1|root,COG0784@1|root,COG1511@1|root,COG2770@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG1511@2|Bacteria,COG2205@2|Bacteria,COG2770@2|Bacteria,1G13T@1117|Cyanobacteria,1HI4W@1150|Oscillatoriales 1117|Cyanobacteria T Response regulator receiver domain - - - - - - - - - - - - CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg SJTD3_k127_7104166_3 316274.Haur_1551 1.347e-34 143.0 COG1496@1|root,COG1496@2|Bacteria,2G6N5@200795|Chloroflexi 200795|Chloroflexi S Belongs to the multicopper oxidase YfiH RL5 family - - - ko:K05810 - - - - ko00000,ko01000 - - - Cu-oxidase_4 SJTD3_k127_7104166_0 479434.Sthe_1183 2.349e-171 557.0 COG4262@1|root,COG4262@2|Bacteria,2G5YS@200795|Chloroflexi 200795|Chloroflexi S Spermine/spermidine synthase domain - - - - - - - - - - - - Spermine_synth SJTD3_k127_7104166_2 1382306.JNIM01000001_gene1292 8.034e-125 409.0 COG1494@1|root,COG1494@2|Bacteria,2G5XR@200795|Chloroflexi 200795|Chloroflexi G TIGRFAM fructose-1,6-bisphosphatase, class II glpX - 3.1.3.11 ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 M00003,M00165,M00167 R00762,R04780 RC00017 ko00000,ko00001,ko00002,ko01000 - - - FBPase_glpX SJTD3_k127_7104166_1 1089553.Tph_c27810 5.079e-157 509.0 COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,42EXD@68295|Thermoanaerobacterales 186801|Clostridia K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template rho - - ko:K03628 ko03018,map03018 - - - ko00000,ko00001,ko03019,ko03021 - - - ATP-synt_ab,Rho_N,Rho_RNA_bind SJTD3_k127_7105092_2 240015.ACP_1356 1.482e-40 170.0 COG4409@1|root,COG4409@2|Bacteria,3Y8VS@57723|Acidobacteria 57723|Acidobacteria G exo-alpha-(2->6)-sialidase activity - - - - - - - - - - - - - SJTD3_k127_7105092_5 1145276.T479_08195 8.483e-09 68.0 COG2911@1|root,COG3209@1|root,COG4632@1|root,COG2911@2|Bacteria,COG3209@2|Bacteria,COG4632@2|Bacteria,1UK8Y@1239|Firmicutes 1239|Firmicutes M Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - - - - - - - - - - Big_4,Flg_new,LRR_5 SJTD3_k127_7105092_4 1347368.HG964403_gene4308 4.014e-11 74.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli,1ZPUS@1386|Bacillus 91061|Bacilli M Cell wall hydrolase autolysin lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH SJTD3_k127_7105092_0 479434.Sthe_0703 2.439e-189 604.0 COG1418@1|root,COG1418@2|Bacteria,2G620@200795|Chloroflexi,27Y2Z@189775|Thermomicrobia 189775|Thermomicrobia S Domain of unknown function (DUF3552) rny - - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 SJTD3_k127_7105092_3 316274.Haur_4794 8.109e-28 119.0 COG2359@1|root,COG2359@2|Bacteria,2G77N@200795|Chloroflexi,375SU@32061|Chloroflexia 32061|Chloroflexia S PFAM Stage V sporulation protein S - - - ko:K06416 - - - - ko00000 - - - SpoVS SJTD3_k127_7105092_1 479434.Sthe_0705 2.523e-74 259.0 COG0613@1|root,COG0613@2|Bacteria,2G6H4@200795|Chloroflexi,27YVQ@189775|Thermomicrobia 189775|Thermomicrobia S DNA polymerase alpha chain like domain - - 3.1.3.97 ko:K07053 - - R00188,R11188 RC00078 ko00000,ko01000 - - - PHP SJTD3_k127_7105092_6 383372.Rcas_2902 3.097e-06 59.0 2EXFW@1|root,33QS7@2|Bacteria,2GAD4@200795|Chloroflexi,375HG@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - - SJTD3_k127_7105537_2 383372.Rcas_0712 2.219e-29 118.0 COG2442@1|root,COG2442@2|Bacteria 2|Bacteria K InterPro IPR007367 - - - - - - - - - - - - DUF433,MerR_1 SJTD3_k127_7105537_1 215803.DB30_2054 1.121e-110 369.0 COG1915@1|root,COG1915@2|Bacteria,1PZ72@1224|Proteobacteria,42MME@68525|delta/epsilon subdivisions,2WJSV@28221|Deltaproteobacteria,2YYT4@29|Myxococcales 28221|Deltaproteobacteria S PFAM LOR SDH bifunctional enzyme conserved region - - - - - - - - - - - - Saccharop_dh_N SJTD3_k127_7105537_0 926569.ANT_10550 3.875e-132 438.0 COG0769@1|root,COG0769@2|Bacteria,2G5U3@200795|Chloroflexi 200795|Chloroflexi M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M SJTD3_k127_7105537_4 926550.CLDAP_34880 1.16e-08 66.0 COG3103@1|root,COG4991@2|Bacteria 2|Bacteria T sh3 domain protein MA20_15015 - - - - - - - - - - - DUF1236,SH3_3 SJTD3_k127_7105537_3 530564.Psta_2797 2.422e-17 94.0 COG0551@1|root,COG0551@2|Bacteria 2|Bacteria L DNA topological change - - - - - - - - - - - - DUF2726,zf-C4_Topoisom SJTD3_k127_7110272_1 649638.Trad_0849 1.018e-76 268.0 COG0673@1|root,COG0673@2|Bacteria,1WJSV@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C SJTD3_k127_7110272_0 266117.Rxyl_0833 3.492e-193 608.0 COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4CS1W@84995|Rubrobacteria 84995|Rubrobacteria G Belongs to the FGGY kinase family - - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N SJTD3_k127_7113965_3 525904.Tter_0788 1.808e-36 143.0 COG0473@1|root,COG0473@2|Bacteria,2NP0Z@2323|unclassified Bacteria 2|Bacteria CE Isocitrate/isopropylmalate dehydrogenase icd - 1.1.1.41 ko:K00030 ko00020,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010 R00709 RC00114 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh SJTD3_k127_7113965_2 383372.Rcas_1304 4.262e-108 364.0 COG0420@1|root,COG0420@2|Bacteria,2G60M@200795|Chloroflexi,3757S@32061|Chloroflexia 32061|Chloroflexia L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos SJTD3_k127_7113965_4 316274.Haur_4222 4.048e-06 61.0 COG0457@1|root,COG3266@1|root,COG0457@2|Bacteria,COG3266@2|Bacteria,2G70Z@200795|Chloroflexi,374SR@32061|Chloroflexia 32061|Chloroflexia S Tetratricopeptide TPR_2 repeat protein - - - - - - - - - - - - Sigma70_r1_1,TPR_16,TPR_19 SJTD3_k127_7113965_0 235909.GK1597 4.414e-137 448.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4HAWZ@91061|Bacilli,1WFD8@129337|Geobacillus 91061|Bacilli C Acyl-CoA dehydrogenase, N-terminal domain yngJ - 1.3.8.1 ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SJTD3_k127_7113965_1 1121472.AQWN01000006_gene1727 9.322e-122 409.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,260C1@186807|Peptococcaceae 186801|Clostridia C Acyl-CoA dehydrogenase, N-terminal - - 1.3.8.1 ko:K00248,ko:K18244 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 - R01175,R01178,R02661,R03172,R04751 RC00052,RC00068,RC00076,RC00120,RC00148 ko00000,ko00001,ko01000 - - - Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N SJTD3_k127_7129250_5 1128421.JAGA01000002_gene434 5.317e-12 68.0 COG1630@1|root,COG1630@2|Bacteria,2NQ5P@2323|unclassified Bacteria 2|Bacteria S NurA - - - - - - - - - - - - NurA SJTD3_k127_7129250_4 292563.Cyast_1561 1.903e-12 76.0 2C7F0@1|root,2Z832@2|Bacteria,1FZVC@1117|Cyanobacteria 1117|Cyanobacteria S PFAM HAS barrel domain - - - - - - - - - - - - HAS-barrel SJTD3_k127_7129250_0 1128421.JAGA01000002_gene1130 1.062e-135 451.0 COG0433@1|root,COG0433@2|Bacteria,2NPZD@2323|unclassified Bacteria 2|Bacteria S Domain of unknown function DUF87 - - - ko:K06915 - - - - ko00000 - - - DUF87,HAS-barrel SJTD3_k127_7129250_3 586416.GZ22_04245 7.293e-38 148.0 2BA2Z@1|root,323GR@2|Bacteria,1VJ99@1239|Firmicutes,4HQNE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - SJTD3_k127_7129250_1 1173024.KI912149_gene5168 5.214e-135 435.0 COG1028@1|root,COG1028@2|Bacteria,1G264@1117|Cyanobacteria,1JGVT@1189|Stigonemataceae 1117|Cyanobacteria IQ Enoyl-(Acyl carrier protein) reductase - - - - - - - - - - - - adh_short_C2 SJTD3_k127_7129250_2 323848.Nmul_A2150 5.497e-100 330.0 COG0438@1|root,COG1232@1|root,COG2723@1|root,COG0438@2|Bacteria,COG1232@2|Bacteria,COG2723@2|Bacteria,1QU2N@1224|Proteobacteria,2VJ9J@28216|Betaproteobacteria,37415@32003|Nitrosomonadales 28216|Betaproteobacteria M Glycosyl transferases group 1 - - - - - - - - - - - - Amino_oxidase,Glyco_trans_1_4,NAD_binding_8 SJTD3_k127_7145525_1 479434.Sthe_2039 4.292e-44 181.0 COG0642@1|root,COG2205@2|Bacteria,2GA7A@200795|Chloroflexi 200795|Chloroflexi T PFAM ATP-binding region, ATPase domain protein - - - - - - - - - - - - HATPase_c,HisKA SJTD3_k127_7145525_2 326427.Cagg_3111 5.906e-25 117.0 COG3764@1|root,COG3764@2|Bacteria,2G98S@200795|Chloroflexi,375IR@32061|Chloroflexia 32061|Chloroflexia M PFAM peptidase C60, sortase A and B - - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase SJTD3_k127_7145525_3 1120966.AUBU01000013_gene320 7.514e-05 55.0 COG1361@1|root,COG1361@2|Bacteria 2|Bacteria M extracellular matrix structural constituent - - - - - - - - - - - - CHU_C,DUF11 SJTD3_k127_7145525_0 643648.Slip_0898 1.067e-63 224.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia 186801|Clostridia F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt - 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran SJTD3_k127_7149167_1 266117.Rxyl_2070 4.347e-98 330.0 COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria 201174|Actinobacteria G PFAM binding-protein-dependent transport systems inner membrane component - - - ko:K17238 ko02010,map02010 M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.38 - - BPD_transp_1 SJTD3_k127_7149167_2 266117.Rxyl_2069 8.423e-98 327.0 COG0395@1|root,COG0395@2|Bacteria,2GJ3P@201174|Actinobacteria,4CR7Y@84995|Rubrobacteria 84995|Rubrobacteria G Binding-protein-dependent transport system inner membrane component - - - ko:K17239 ko02010,map02010 M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.38 - - BPD_transp_1 SJTD3_k127_7149167_0 266117.Rxyl_2068 5.305e-123 404.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CPPT@84995|Rubrobacteria 84995|Rubrobacteria P Belongs to the ABC transporter superfamily - - - ko:K17240 ko02010,map02010 M00599 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.38 - - ABC_tran,TOBE_2 SJTD3_k127_7149167_3 911045.PSE_p0235 4.819e-46 177.0 COG1011@1|root,COG1011@2|Bacteria 2|Bacteria S phosphatase activity - - - ko:K07025 - - - - ko00000 - - - HAD_2 SJTD3_k127_7149167_4 1110502.TMO_3302 1.398e-06 59.0 COG0584@1|root,COG0584@2|Bacteria,1MU8H@1224|Proteobacteria,2UDP0@28211|Alphaproteobacteria,2JSCG@204441|Rhodospirillales 204441|Rhodospirillales C glycerophosphoryl diester phosphodiesterase ugpQ - 3.1.4.46 ko:K01126 ko00564,map00564 - R01030,R01470 RC00017,RC00425 ko00000,ko00001,ko01000 - - - GDPD SJTD3_k127_7151149_2 404589.Anae109_3355 1.338e-52 193.0 COG2197@1|root,COG2197@2|Bacteria,1NQH7@1224|Proteobacteria 1224|Proteobacteria K response regulator - - - ko:K07685 ko02020,map02020 M00472 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg SJTD3_k127_7151149_0 404589.Anae109_3354 5.62e-118 400.0 COG4585@1|root,COG4585@2|Bacteria,1RBN9@1224|Proteobacteria 1224|Proteobacteria T Histidine kinase - - - - - - - - - - - - HisKA_3 SJTD3_k127_7151149_1 1128421.JAGA01000002_gene866 8.012e-53 188.0 COG1063@1|root,COG1063@2|Bacteria 2|Bacteria E alcohol dehydrogenase MA20_31690 - 1.1.1.14 ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 M00014 R00875,R01896 RC00085,RC00102 ko00000,ko00001,ko00002,ko01000 - - - ADH_N,ADH_zinc_N SJTD3_k127_7152999_4 1254432.SCE1572_20265 2.624e-13 70.0 COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,42M9C@68525|delta/epsilon subdivisions,2WJ75@28221|Deltaproteobacteria,2YV0S@29|Myxococcales 28221|Deltaproteobacteria E ABC transporter - - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C SJTD3_k127_7152999_2 1254432.SCE1572_20260 8.572e-104 345.0 COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,42QV6@68525|delta/epsilon subdivisions,2WMN1@28221|Deltaproteobacteria,2Z08T@29|Myxococcales 28221|Deltaproteobacteria E Branched-chain amino acid ATP-binding cassette transporter - - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C SJTD3_k127_7152999_1 1254432.SCE1572_20255 2.794e-109 377.0 COG4177@1|root,COG4177@2|Bacteria,1NPII@1224|Proteobacteria,42TEH@68525|delta/epsilon subdivisions,2WPV9@28221|Deltaproteobacteria 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SJTD3_k127_7152999_0 1254432.SCE1572_20250 1.068e-114 376.0 COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997,ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SJTD3_k127_7152999_3 1254432.SCE1572_20250 2.095e-21 94.0 COG0559@1|root,COG0683@1|root,COG0559@2|Bacteria,COG0683@2|Bacteria,1N5XH@1224|Proteobacteria,42PN7@68525|delta/epsilon subdivisions,2WIRP@28221|Deltaproteobacteria,2Z0ZI@29|Myxococcales 28221|Deltaproteobacteria U Belongs to the binding-protein-dependent transport system permease family - - - ko:K01997,ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 SJTD3_k127_7165814_0 479434.Sthe_0357 1.249e-28 132.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_7165814_1 1144275.COCOR_00334 1.49e-20 95.0 COG2227@1|root,COG2227@2|Bacteria,1QWVE@1224|Proteobacteria 1224|Proteobacteria H Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 SJTD3_k127_7190267_1 1128421.JAGA01000002_gene1285 5.348e-44 170.0 2E2J3@1|root,32XNM@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_7190267_0 316274.Haur_3686 2.134e-48 185.0 COG1705@1|root,COG1705@2|Bacteria,2G9KG@200795|Chloroflexi,375T2@32061|Chloroflexia 32061|Chloroflexia NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase - - - - - - - - - - - - Glucosaminidase SJTD3_k127_7190267_2 1128421.JAGA01000003_gene2785 6.89e-09 61.0 COG0472@1|root,COG0472@2|Bacteria,2NR03@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase family 4 - - 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - CoA_binding_3,Glycos_transf_4 SJTD3_k127_7191045_0 1128421.JAGA01000002_gene1962 7.591e-92 311.0 COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2NQDQ@2323|unclassified Bacteria 2|Bacteria P Rhodanese Homology Domain baeB - 3.1.2.6,3.4.21.102 ko:K01069,ko:K03797 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000,ko01002 - - - Lactamase_B,Rhodanese SJTD3_k127_7191045_2 448385.sce7865 0.0003596 49.0 COG3189@1|root,COG3189@2|Bacteria,1MZ7H@1224|Proteobacteria,42U37@68525|delta/epsilon subdivisions,2WQ9M@28221|Deltaproteobacteria,2Z1YM@29|Myxococcales 28221|Deltaproteobacteria S Protein of unknown function, DUF488 - - - - - - - - - - - - DUF488 SJTD3_k127_7191045_1 1173023.KE650771_gene2827 2.422e-09 70.0 COG0457@1|root,COG0457@2|Bacteria,1G4DP@1117|Cyanobacteria,1JI6C@1189|Stigonemataceae 1117|Cyanobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_1,TPR_10,TPR_11,TPR_8 SJTD3_k127_7193229_0 1051632.TPY_3259 7.25e-64 230.0 COG0438@1|root,COG0438@2|Bacteria,1VC00@1239|Firmicutes 1239|Firmicutes M Glycosyl transferases group 1 - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_7193229_2 269799.Gmet_2032 3.798e-08 66.0 COG0457@1|root,COG0457@2|Bacteria,1MXMD@1224|Proteobacteria,42P80@68525|delta/epsilon subdivisions,2WMCB@28221|Deltaproteobacteria,43TGI@69541|Desulfuromonadales 28221|Deltaproteobacteria S Tetratricopeptide repeat - - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_8 SJTD3_k127_7193229_1 485916.Dtox_1644 1.342e-12 78.0 COG1427@1|root,COG1427@2|Bacteria,1V2PX@1239|Firmicutes,24CGN@186801|Clostridia,2618R@186807|Peptococcaceae 186801|Clostridia H Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) mqnA - 4.2.1.151 ko:K11782 ko00130,ko01110,map00130,map01110 - R10666 RC03232 ko00000,ko00001,ko01000 - - - VitK2_biosynth SJTD3_k127_7195675_5 1121085.AUCI01000006_gene1583 2.199e-114 377.0 COG0329@1|root,COG0329@2|Bacteria 2|Bacteria E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) - - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS SJTD3_k127_7195675_11 1280390.CBQR020000061_gene1169 5.999e-58 214.0 COG2017@1|root,COG2017@2|Bacteria,1TQVE@1239|Firmicutes,4HFJM@91061|Bacilli,26U0H@186822|Paenibacillaceae 91061|Bacilli G converts alpha-aldose to the beta-anomer - - - - - - - - - - - - Aldose_epim,DUF4432 SJTD3_k127_7195675_1 485913.Krac_10071 1.278e-197 631.0 COG1012@1|root,COG1012@2|Bacteria,2G898@200795|Chloroflexi 200795|Chloroflexi C Aldehyde dehydrogenase family - - 1.2.1.26 ko:K13877 ko00040,ko00053,map00040,map00053 - R00264 RC00080 ko00000,ko00001,ko01000 - - - Aldedh SJTD3_k127_7195675_4 485913.Krac_5800 7.936e-118 389.0 COG1063@1|root,COG1063@2|Bacteria,2G5WK@200795|Chloroflexi 200795|Chloroflexi C Alcohol dehydrogenase zinc-binding domain protein - - 1.1.1.103 ko:K00060 ko00260,map00260 - R01465 RC00525 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N SJTD3_k127_7195675_0 1033743.CAES01000007_gene2016 1.747e-201 632.0 COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,4HC1G@91061|Bacilli,26VB1@186822|Paenibacillaceae 91061|Bacilli M mandelate racemase muconate lactonizing - - - - - - - - - - - - MR_MLE_C,MR_MLE_N SJTD3_k127_7195675_3 1382306.JNIM01000001_gene2724 8.627e-125 403.0 COG1028@1|root,COG1028@2|Bacteria,2G8K5@200795|Chloroflexi 200795|Chloroflexi IQ PFAM short-chain dehydrogenase reductase SDR - - 1.1.1.100,1.5.1.33 ko:K00059,ko:K03793 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SJTD3_k127_7195675_9 1499967.BAYZ01000073_gene2029 1.529e-73 254.0 COG2755@1|root,COG2755@2|Bacteria 2|Bacteria E lipolytic protein G-D-S-L family - - - - - - - - - - - - Lipase_GDSL_2 SJTD3_k127_7195675_7 1089552.KI911559_gene1070 3.416e-82 282.0 COG3386@1|root,COG3386@2|Bacteria,1MWTR@1224|Proteobacteria,2TUTF@28211|Alphaproteobacteria,2JSIT@204441|Rhodospirillales 204441|Rhodospirillales G SMP-30/Gluconolaconase/LRE-like region - - - ko:K14274 ko00040,map00040 - R02427 RC00713 ko00000,ko00001,ko01000 - - - SGL SJTD3_k127_7195675_10 357808.RoseRS_2515 1.476e-70 246.0 COG1028@1|root,COG1028@2|Bacteria,2G8DK@200795|Chloroflexi,3776U@32061|Chloroflexia 32061|Chloroflexia IQ short-chain dehydrogenase reductase SDR - - - - - - - - - - - - adh_short_C2 SJTD3_k127_7195675_2 383372.Rcas_2758 6.883e-139 449.0 COG0620@1|root,COG0620@2|Bacteria,2G7J6@200795|Chloroflexi,377RE@32061|Chloroflexia 32061|Chloroflexia H PFAM Methionine synthase, vitamin-B12 independent - - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 SJTD3_k127_7195675_13 351607.Acel_0569 7.083e-23 101.0 COG1053@1|root,COG1053@2|Bacteria,2HD4N@201174|Actinobacteria 201174|Actinobacteria C FAD dependent oxidoreductase - - - - - - - - - - - - FAD_oxidored SJTD3_k127_7195675_6 1267535.KB906767_gene3414 1.049e-107 367.0 COG1070@1|root,COG1070@2|Bacteria,3Y2V6@57723|Acidobacteria,2JJ35@204432|Acidobacteriia 204432|Acidobacteriia G FGGY family of carbohydrate kinases, N-terminal domain xylB - 2.7.1.17 ko:K00854 ko00040,ko01100,map00040,map01100 M00014 R01639 RC00002,RC00538 ko00000,ko00001,ko00002,ko01000 - - - FGGY_C,FGGY_N SJTD3_k127_7195675_8 926550.CLDAP_29730 4.303e-76 264.0 COG4821@1|root,COG4821@2|Bacteria,2G6XP@200795|Chloroflexi 200795|Chloroflexi S SIS domain - - - - - - - - - - - - SIS_2 SJTD3_k127_7195675_12 1118054.CAGW01000071_gene1790 1.291e-52 194.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,26Z0J@186822|Paenibacillaceae 91061|Bacilli K UTRA frlR3 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA SJTD3_k127_7206554_1 1379270.AUXF01000003_gene3868 1.544e-19 96.0 2AEWX@1|root,314UJ@2|Bacteria,1ZUPP@142182|Gemmatimonadetes 142182|Gemmatimonadetes - - - - - - - - - - - - - - - SJTD3_k127_7206554_0 404380.Gbem_1051 2.905e-34 145.0 COG1287@1|root,COG1287@2|Bacteria,1N1IK@1224|Proteobacteria,42RRN@68525|delta/epsilon subdivisions,2WNAY@28221|Deltaproteobacteria,43SI2@69541|Desulfuromonadales 28221|Deltaproteobacteria S IMG reference gene - - - - - - - - - - - - - SJTD3_k127_7209924_1 526225.Gobs_2142 4.273e-94 349.0 COG3391@1|root,COG4995@1|root,COG3391@2|Bacteria,COG4995@2|Bacteria,2HF98@201174|Actinobacteria,4EWDJ@85013|Frankiales 201174|Actinobacteria S amine dehydrogenase activity - - - - - - - - - - - - - SJTD3_k127_7209924_2 316274.Haur_0717 3.765e-45 190.0 COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,2G5NM@200795|Chloroflexi,3755B@32061|Chloroflexia 200795|Chloroflexi KLT Serine threonine protein kinase - - - - - - - - - - - - Pkinase SJTD3_k127_7209924_3 316274.Haur_0854 8.391e-13 79.0 COG0515@1|root,COG0515@2|Bacteria,2G9EP@200795|Chloroflexi,375W6@32061|Chloroflexia 32061|Chloroflexia KLT serine threonine protein kinase - - - - - - - - - - - - zinc_ribbon_2 SJTD3_k127_7209924_0 313589.JNB_12119 7.163e-247 779.0 COG1404@1|root,COG1404@2|Bacteria,2GKJR@201174|Actinobacteria,4FFMV@85021|Intrasporangiaceae 201174|Actinobacteria O Belongs to the peptidase S8 family - - - - - - - - - - - - PPC,Peptidase_S8 SJTD3_k127_7218775_4 1142394.PSMK_22050 1.509e-21 105.0 28SBZ@1|root,2ZENV@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_7218775_5 1347368.HG964403_gene4308 4.05e-10 74.0 COG0860@1|root,COG3103@1|root,COG0860@2|Bacteria,COG3103@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli,1ZPUS@1386|Bacillus 91061|Bacilli M Cell wall hydrolase autolysin lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH SJTD3_k127_7218775_3 1120949.KB903357_gene4933 1.434e-25 125.0 COG4447@1|root,COG4447@2|Bacteria,2IT8P@201174|Actinobacteria 201174|Actinobacteria M phospholipase C - - - - - - - - - - - - - SJTD3_k127_7218775_2 945713.IALB_1831 6.264e-26 126.0 COG4409@1|root,COG4447@1|root,COG4409@2|Bacteria,COG4447@2|Bacteria 2|Bacteria S cellulose binding - - - - - - - - - - - - CelD_N,Glyco_hydro_9 SJTD3_k127_7218775_0 485913.Krac_9124 1.659e-122 409.0 COG0436@1|root,COG0436@2|Bacteria 2|Bacteria E Aminotransferase - - - - - - - - - - - - Aminotran_1_2 SJTD3_k127_7218775_1 316274.Haur_3383 5.927e-60 222.0 COG2730@1|root,COG5479@1|root,COG2730@2|Bacteria,COG5479@2|Bacteria,2G7Y2@200795|Chloroflexi,374T3@32061|Chloroflexia 32061|Chloroflexia G Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - - - - - - - - - - Cellulase SJTD3_k127_7226274_1 987059.RBXJA2T_01620 1.259e-39 153.0 COG2304@1|root,COG2304@2|Bacteria,1MXQ7@1224|Proteobacteria,2VHRY@28216|Betaproteobacteria,1KKCR@119065|unclassified Burkholderiales 28216|Betaproteobacteria S Von Willebrand factor type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 SJTD3_k127_7226274_0 675635.Psed_0414 1.064e-69 248.0 COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria,4DYPB@85010|Pseudonocardiales 201174|Actinobacteria S von Willebrand factor, type A - - - ko:K07114 - - - - ko00000,ko02000 1.A.13.2.2,1.A.13.2.3 - - BatA,VWA,VWA_2 SJTD3_k127_7230961_2 479434.Sthe_0506 2.453e-38 156.0 COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi,27XKD@189775|Thermomicrobia 189775|Thermomicrobia U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - SJTD3_k127_7230961_1 479434.Sthe_0506 2.923e-46 190.0 COG0823@1|root,COG0823@2|Bacteria,2G78A@200795|Chloroflexi,27XKD@189775|Thermomicrobia 189775|Thermomicrobia U Involved in the tonB-independent uptake of proteins - - - - - - - - - - - - - SJTD3_k127_7230961_0 1242864.D187_005544 1.589e-84 293.0 COG1819@1|root,COG1819@2|Bacteria,1PVC0@1224|Proteobacteria,434ZI@68525|delta/epsilon subdivisions,2WZAA@28221|Deltaproteobacteria,2Z1PJ@29|Myxococcales 28221|Deltaproteobacteria CG UDP-glucoronosyl and UDP-glucosyl transferase - - - - - - - - - - - - UDPGT SJTD3_k127_7233767_1 211114.JOEF01000016_gene3742 5.495e-05 48.0 COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4E030@85010|Pseudonocardiales 201174|Actinobacteria G Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system - - - - - - - - - - - - Glyco_hydro_63,Trehalase SJTD3_k127_7233767_0 1122223.KB890696_gene268 4.391e-117 389.0 COG1063@1|root,COG1063@2|Bacteria,1WM0J@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus E Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_zinc_N SJTD3_k127_7235156_1 1089553.Tph_c09570 1.949e-22 107.0 COG1073@1|root,COG1073@2|Bacteria,1UXYN@1239|Firmicutes,24DU6@186801|Clostridia,42G65@68295|Thermoanaerobacterales 186801|Clostridia S PFAM alpha beta hydrolase - - - ko:K06889,ko:K07397 - - - - ko00000 - - - Abhydrolase_1,Hydrolase_4,Peptidase_S9 SJTD3_k127_7235156_0 748727.CLJU_c34100 1.778e-71 246.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,248NW@186801|Clostridia,36FEX@31979|Clostridiaceae 186801|Clostridia M Belongs to the UDP-glucose GDP-mannose dehydrogenase family wbpA2 - 1.1.1.136 ko:K13015 ko00520,map00520 - R00421 RC00291 ko00000,ko00001,ko01000,ko01005 - - - UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N SJTD3_k127_7235376_2 479434.Sthe_1814 7.295e-35 138.0 COG1999@1|root,COG3391@1|root,COG1999@2|Bacteria,COG3391@2|Bacteria,2GAQJ@200795|Chloroflexi,27XX5@189775|Thermomicrobia 189775|Thermomicrobia S signal sequence binding - - - - - - - - - - - - NHL SJTD3_k127_7235376_0 1217718.ALOU01000025_gene4205 1.286e-116 385.0 COG2197@1|root,COG2267@1|root,COG2197@2|Bacteria,COG2267@2|Bacteria,1NXKF@1224|Proteobacteria,2W0UU@28216|Betaproteobacteria,1K4Z4@119060|Burkholderiaceae 28216|Betaproteobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE,PAS_8,PAS_9 SJTD3_k127_7235376_1 485913.Krac_11708 8.539e-57 208.0 COG2197@1|root,COG2909@1|root,COG3903@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulator, LuxR family - - - - - - - - - - - - AAA_22,GerE,NB-ARC,TPR_12 SJTD3_k127_7240203_1 616991.JPOO01000003_gene2629 8.217e-119 387.0 COG2170@1|root,COG2170@2|Bacteria,4NFFP@976|Bacteroidetes,1HZNS@117743|Flavobacteriia 976|Bacteroidetes S ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity ybdK - - ko:K06048 - - - - ko00000,ko01000 - - - GCS2 SJTD3_k127_7240203_2 349741.Amuc_1436 1.356e-116 383.0 COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae 203494|Verrucomicrobiae C Catalyzes the reversible oxidation of malate to oxaloacetate - - 1.1.1.37 ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 R00342,R07136 RC00031 ko00000,ko00001,ko00002,ko01000 - - - Ldh_1_C,Ldh_1_N SJTD3_k127_7240203_0 163908.KB235896_gene60 1.799e-136 444.0 COG3288@1|root,COG3288@2|Bacteria,1G1D1@1117|Cyanobacteria,1HJ2V@1161|Nostocales 1117|Cyanobacteria C PFAM Alanine dehydrogenase PNT, C-terminal domain pntA - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N SJTD3_k127_7240203_4 479434.Sthe_1946 9.426e-26 112.0 COG3288@1|root,COG3288@2|Bacteria,2GBAD@200795|Chloroflexi,27YI1@189775|Thermomicrobia 189775|Thermomicrobia C 4TM region of pyridine nucleotide transhydrogenase, mitoch - - 1.6.1.2 ko:K00324 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB_4TM SJTD3_k127_7240203_3 479434.Sthe_1947 6.843e-51 190.0 COG1282@1|root,COG1282@2|Bacteria,2GB8C@200795|Chloroflexi,27Y0C@189775|Thermomicrobia 189775|Thermomicrobia C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane - - 1.6.1.2 ko:K00325 ko00760,ko01100,map00760,map01100 - R00112 RC00001 ko00000,ko00001,ko01000 - - - PNTB SJTD3_k127_7241174_1 383372.Rcas_2533 2.004e-53 198.0 COG0596@1|root,COG0596@2|Bacteria 2|Bacteria S hydrolase activity, acting on ester bonds MA20_06765 - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 SJTD3_k127_7241174_0 221288.JH992901_gene4311 1.68e-76 264.0 COG2227@1|root,COG2227@2|Bacteria,1GQZP@1117|Cyanobacteria,1JKUR@1189|Stigonemataceae 1117|Cyanobacteria H Nodulation protein S (NodS) - - - - - - - - - - - - Methyltransf_11 SJTD3_k127_7241174_2 485913.Krac_2128 1.717e-30 121.0 COG1541@1|root,COG1541@2|Bacteria,2G695@200795|Chloroflexi 200795|Chloroflexi H AMP-binding enzyme - - 6.2.1.30 ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 - R02539 RC00004,RC00014 ko00000,ko00001,ko01000 - - - AMP-binding,AMP-binding_C_2 SJTD3_k127_7257937_1 926550.CLDAP_38610 6.173e-104 345.0 COG1129@1|root,COG1129@2|Bacteria,2G649@200795|Chloroflexi 200795|Chloroflexi P Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system - - 3.6.3.17 ko:K02056,ko:K10441 ko02010,map02010 M00212,M00221 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_7257937_2 926550.CLDAP_38620 1.397e-98 332.0 COG1172@1|root,COG1172@2|Bacteria 2|Bacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SJTD3_k127_7257937_0 1499967.BAYZ01000022_gene241 5.083e-111 370.0 COG1172@1|root,COG1172@2|Bacteria 2|Bacteria G Belongs to the binding-protein-dependent transport system permease family - - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 SJTD3_k127_72654_4 526227.Mesil_1129 1.733e-36 143.0 COG0697@1|root,COG0697@2|Bacteria,1WKUM@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus EG PFAM EamA-like transporter family - - - - - - - - - - - - - SJTD3_k127_72654_0 1128421.JAGA01000002_gene1871 5.404e-201 639.0 COG0696@1|root,COG0696@2|Bacteria,2NP1Y@2323|unclassified Bacteria 2|Bacteria G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmI GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000 - - iECSE_1348.ECSE_3895,iJN678.yibO,iJN746.PP_5056 Metalloenzyme,Phosphodiest,iPGM_N SJTD3_k127_72654_2 1382306.JNIM01000001_gene908 4.287e-70 243.0 COG0717@1|root,COG0717@2|Bacteria 2|Bacteria F dUTP biosynthetic process dcd - 3.5.4.13 ko:K01494 ko00240,ko01100,map00240,map01100 M00053 R00568,R02325 RC00074 ko00000,ko00001,ko00002,ko01000 - - - dUTPase SJTD3_k127_72654_1 1121472.AQWN01000002_gene2290 9.733e-108 362.0 COG0297@1|root,COG0297@2|Bacteria,1UHYC@1239|Firmicutes,24ANR@186801|Clostridia,260MR@186807|Peptococcaceae 186801|Clostridia G PFAM Glycosyl transferase, group 1 - - 2.4.1.11 ko:K16150 ko00500,ko01100,map00500,map01100 - R00292 RC00005 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_72654_3 479434.Sthe_0977 3.416e-52 196.0 COG0454@1|root,COG0456@2|Bacteria,2G7CX@200795|Chloroflexi,27Y6X@189775|Thermomicrobia 189775|Thermomicrobia K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_7270649_0 1128421.JAGA01000002_gene877 0.0 1269.0 COG0085@1|root,COG0085@2|Bacteria,2NNM9@2323|unclassified Bacteria 2|Bacteria K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 SJTD3_k127_7270649_1 765420.OSCT_1426 5.184e-106 349.0 COG1126@1|root,COG1126@2|Bacteria,2G5UB@200795|Chloroflexi,376F8@32061|Chloroflexia 32061|Chloroflexia E PFAM ABC transporter related - - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran SJTD3_k127_7270649_2 574375.BAGA_06510 2.623e-32 136.0 COG0765@1|root,COG0765@2|Bacteria,1UJM4@1239|Firmicutes,4HBAS@91061|Bacilli,1ZCE8@1386|Bacillus 91061|Bacilli P ABC transporter glnP GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 SJTD3_k127_7275018_0 479434.Sthe_1174 2.837e-159 543.0 COG1807@1|root,COG5427@1|root,COG1807@2|Bacteria,COG5427@2|Bacteria,2G5UJ@200795|Chloroflexi,27Y0P@189775|Thermomicrobia 189775|Thermomicrobia M Uncharacterized membrane protein (DUF2298) - - - - - - - - - - - - DUF2298,PMT_2 SJTD3_k127_7275018_1 1562701.BBOF01000053_gene1471 1.903e-24 107.0 COG1051@1|root,COG1051@2|Bacteria,1REBW@1224|Proteobacteria,2VQ39@28216|Betaproteobacteria,1K0AH@119060|Burkholderiaceae 28216|Betaproteobacteria F Belongs to the Nudix hydrolase family nudC_1 - - - - - - - - - - - NUDIX,Nudix_N_2 SJTD3_k127_7277468_1 1123073.KB899241_gene2080 1.494e-114 379.0 COG0463@1|root,COG0463@2|Bacteria,1MWE5@1224|Proteobacteria,1RPCE@1236|Gammaproteobacteria,1XCJS@135614|Xanthomonadales 135614|Xanthomonadales M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_7277468_0 1128427.KB904821_gene205 2.609e-222 706.0 COG0367@1|root,COG0367@2|Bacteria,1G1WZ@1117|Cyanobacteria,1H9W9@1150|Oscillatoriales 1117|Cyanobacteria E Asparagine synthase asnB - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase,GATase_7 SJTD3_k127_7277468_2 596152.DesU5LDRAFT_0903 1.82e-96 329.0 COG0438@1|root,COG0438@2|Bacteria,1RH5W@1224|Proteobacteria,42UY3@68525|delta/epsilon subdivisions,2WQ9B@28221|Deltaproteobacteria,2MA2D@213115|Desulfovibrionales 28221|Deltaproteobacteria M PFAM Glycosyl transferase, group 1 - - - - - - - - - - - - Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1 SJTD3_k127_7277468_3 1047013.AQSP01000132_gene1691 1.249e-19 92.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase ermC - 2.1.1.137 ko:K07755 - - - - ko00000,ko01000 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31,Ubie_methyltran SJTD3_k127_7307092_3 1121946.AUAX01000019_gene7812 1.497e-15 91.0 COG2931@1|root,COG2931@2|Bacteria,2GR03@201174|Actinobacteria,4DM29@85008|Micromonosporales 201174|Actinobacteria Q Haemolysin-type calcium-binding repeat (2 copies) - - - - - - - - - - - - An_peroxidase,HemolysinCabind,Peptidase_M91,fn3 SJTD3_k127_7307092_2 1089545.KB913037_gene6370 8.966e-63 223.0 COG0745@1|root,COG0745@2|Bacteria,2GJ2N@201174|Actinobacteria,4DZ76@85010|Pseudonocardiales 201174|Actinobacteria T Member of the two-component regulatory system kdpD kdpE involved in the regulation of the kdp operon kdpE - - ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 M00454 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C SJTD3_k127_7307092_1 1382306.JNIM01000001_gene1820 5.319e-93 327.0 COG0642@1|root,COG2205@2|Bacteria,2G6KS@200795|Chloroflexi 200795|Chloroflexi T histidine kinase A domain protein - - 2.7.13.3 ko:K07646 ko02020,map02020 M00454 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - DUF4118,GAF,HATPase_c,HisKA SJTD3_k127_7307092_4 485913.Krac_1222 2.3e-12 74.0 COG0745@1|root,COG0745@2|Bacteria,2G9SH@200795|Chloroflexi 485913.Krac_1222|- T SPTR D1CGX5 Response regulator receiver protein - - - - - - - - - - - - - SJTD3_k127_7307092_0 309801.trd_0080 3.964e-99 339.0 COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,27XGG@189775|Thermomicrobia 189775|Thermomicrobia E Amino acid permease - - - - - - - - - - - - AA_permease_2 SJTD3_k127_7321413_0 309801.trd_1938 6.285e-108 352.0 COG1077@1|root,COG1077@2|Bacteria,2G62K@200795|Chloroflexi,27XN7@189775|Thermomicrobia 189775|Thermomicrobia D Cell division protein FtsA - - - ko:K03569 - - - - ko00000,ko02048,ko03036,ko04812 1.A.33.1,9.B.157.1 - - MreB_Mbl SJTD3_k127_7321413_2 197221.22295670 1.47e-43 175.0 COG0863@1|root,COG0863@2|Bacteria,1G2W1@1117|Cyanobacteria 1117|Cyanobacteria L PFAM DNA methylase - - 2.1.1.113 ko:K00590 - - - - ko00000,ko01000,ko02048 - - - N6_N4_Mtase SJTD3_k127_7321413_1 485913.Krac_4643 4.28e-81 276.0 COG2141@1|root,COG2141@2|Bacteria,2G5QC@200795|Chloroflexi 200795|Chloroflexi C PFAM Luciferase-like monooxygenase - - - - - - - - - - - - Bac_luciferase SJTD3_k127_7324937_2 324057.Pjdr2_2585 1.099e-39 154.0 COG0500@1|root,COG2226@2|Bacteria,1V1WV@1239|Firmicutes,4HFQ9@91061|Bacilli,26SKG@186822|Paenibacillaceae 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_25 SJTD3_k127_7324937_1 479434.Sthe_1006 3.452e-91 314.0 COG0644@1|root,COG0644@2|Bacteria 2|Bacteria C geranylgeranyl reductase activity fixC - 1.3.99.38 ko:K21401 - - - - ko00000,ko01000 - - - DAO,FAD_binding_3,Trp_halogenase SJTD3_k127_7324937_3 479434.Sthe_1005 2.409e-36 144.0 COG2867@1|root,COG2867@2|Bacteria 2|Bacteria I negative regulation of translational initiation - - - ko:K05554,ko:K15885 ko01056,ko01130,map01056,map01130 M00778 R09265,R09268 RC02546,RC02547 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Polyketide_cyc,Polyketide_cyc2 SJTD3_k127_7324937_0 525904.Tter_0021 7.916e-149 482.0 COG0304@1|root,COG0304@2|Bacteria,2NNSX@2323|unclassified Bacteria 2|Bacteria I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabB - 2.3.1.179,2.3.1.41 ko:K00647,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt SJTD3_k127_7329991_3 1423747.BAMJ01000013_gene1035 9.913e-09 61.0 COG2231@1|root,COG2231@2|Bacteria,1V4SG@1239|Firmicutes,4HI5U@91061|Bacilli,3F62T@33958|Lactobacillaceae 91061|Bacilli L Base excision DNA repair protein, HhH-GPD family nth2 - - ko:K07457 - - - - ko00000 - - - HhH-GPD SJTD3_k127_7329991_0 455632.SGR_4336 1.077e-33 142.0 COG2606@1|root,COG2606@2|Bacteria,2IKUX@201174|Actinobacteria,41AJX@629295|Streptomyces griseus group 201174|Actinobacteria S Aminoacyl-tRNA editing domain - - - - - - - - - - - - tRNA_edit SJTD3_k127_7329991_1 926569.ANT_03380 2.181e-29 121.0 COG0239@1|root,COG0239@2|Bacteria,2G760@200795|Chloroflexi 200795|Chloroflexi D Important for reducing fluoride concentration in the cell, thus reducing its toxicity crcB GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - ko:K06199 - - - - ko00000,ko02000 1.A.43.1,1.A.43.2,1.A.43.3 - - CRCB SJTD3_k127_7329991_2 1304888.ATWF01000002_gene3 7.201e-19 91.0 COG1993@1|root,COG1993@2|Bacteria,2GFVM@200930|Deferribacteres 200930|Deferribacteres S Uncharacterized ACR, COG1993 - - - ko:K09137 - - - - ko00000 - - - DUF190 SJTD3_k127_7344465_3 1382304.JNIL01000001_gene14 2.763e-26 113.0 COG0477@1|root,COG2814@2|Bacteria,1TPPY@1239|Firmicutes,4HNJ9@91061|Bacilli 91061|Bacilli EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_7344465_4 1296416.JACB01000010_gene1522 0.0003029 53.0 COG2834@1|root,COG3391@1|root,COG2834@2|Bacteria,COG3391@2|Bacteria,4NNEF@976|Bacteroidetes,1I9S0@117743|Flavobacteriia,2YM4C@290174|Aquimarina 976|Bacteroidetes M Cadherin repeats. - - - - - - - - - - - - Cadherin,NHL SJTD3_k127_7344465_0 926569.ANT_12710 2.636e-93 312.0 COG1122@1|root,COG1122@2|Bacteria,2G6RD@200795|Chloroflexi 200795|Chloroflexi P ABC transporter - - - ko:K02006 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - ABC_tran SJTD3_k127_7344465_1 926569.ANT_12700 2.39e-86 293.0 COG0619@1|root,COG0619@2|Bacteria,2G7CE@200795|Chloroflexi 200795|Chloroflexi P TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ cbiQ - - ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiQ SJTD3_k127_7344465_2 926569.ANT_12690 1.028e-80 276.0 COG0310@1|root,COG0310@2|Bacteria,2G6ZN@200795|Chloroflexi 200795|Chloroflexi P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import - - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM,PDGLE SJTD3_k127_7351818_0 867845.KI911784_gene3310 2.223e-202 648.0 COG0445@1|root,COG0445@2|Bacteria,2G629@200795|Chloroflexi,376CM@32061|Chloroflexia 32061|Chloroflexia D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc SJTD3_k127_7351818_1 479434.Sthe_1642 5.831e-65 232.0 COG0639@1|root,COG0639@2|Bacteria,2G6GC@200795|Chloroflexi,27Y5S@189775|Thermomicrobia 189775|Thermomicrobia T Calcineurin-like phosphoesterase superfamily domain - - - - - - - - - - - - Metallophos_2 SJTD3_k127_7354090_0 1123368.AUIS01000023_gene904 2.394e-107 361.0 COG0019@1|root,COG0019@2|Bacteria,1MUA6@1224|Proteobacteria,1RMI2@1236|Gammaproteobacteria,2NBWU@225057|Acidithiobacillales 225057|Acidithiobacillales E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC SJTD3_k127_7354090_1 383372.Rcas_2653 1.619e-27 123.0 COG3947@1|root,COG3947@2|Bacteria 2|Bacteria T sequence-specific DNA binding - - - - - - - - - - - - BTAD,Trans_reg_C SJTD3_k127_7359137_0 886293.Sinac_1249 1.725e-277 878.0 COG3459@1|root,COG3459@2|Bacteria,2IYJ0@203682|Planctomycetes 203682|Planctomycetes G Putative glucoamylase - - - ko:K13688 - - - - ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase SJTD3_k127_7364309_0 1382306.JNIM01000001_gene2493 6.226e-99 326.0 COG1012@1|root,COG1012@2|Bacteria,2G86D@200795|Chloroflexi 200795|Chloroflexi C Aldehyde dehydrogenase family - - - - - - - - - - - - Aldedh SJTD3_k127_7364309_1 1157637.KB892135_gene3548 2.41e-65 240.0 COG0421@1|root,COG0421@2|Bacteria 2|Bacteria E spermidine synthase activity - - - - - - - - - - - - Spermine_synth SJTD3_k127_7392159_3 1195236.CTER_5538 2.409e-17 86.0 2BZS9@1|root,2ZC3V@2|Bacteria,1V250@1239|Firmicutes,24EXQ@186801|Clostridia,3WK70@541000|Ruminococcaceae 186801|Clostridia - - - - - - - - - - - - - - DinB_2 SJTD3_k127_7392159_1 1382356.JQMP01000004_gene653 1.222e-35 150.0 COG1376@1|root,COG3103@1|root,COG3420@1|root,COG1376@2|Bacteria,COG3103@2|Bacteria,COG3420@2|Bacteria,2GBHA@200795|Chloroflexi,27XMC@189775|Thermomicrobia 189775|Thermomicrobia PT N-acetylmuramoyl-L-alanine amidase - - - - - - - - - - - - Amidase_2 SJTD3_k127_7392159_0 357808.RoseRS_2358 1.246e-74 274.0 COG1525@1|root,COG1572@1|root,COG1525@2|Bacteria,COG1572@2|Bacteria,2G86R@200795|Chloroflexi,3757A@32061|Chloroflexia 32061|Chloroflexia G PFAM peptidase domain protein - - - - - - - - - - - - NPCBM_assoc,PPC SJTD3_k127_7392159_2 765420.OSCT_1906 9.758e-23 114.0 COG2340@1|root,COG2340@2|Bacteria 2|Bacteria S peptidase inhibitor activity - - - - - - - - - - - - CAP SJTD3_k127_7394742_0 1382306.JNIM01000001_gene1832 4.655e-177 570.0 COG1529@1|root,COG1529@2|Bacteria,2G608@200795|Chloroflexi 200795|Chloroflexi C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - 1.2.5.3 ko:K03520 - - R11168 RC02800 ko00000,ko01000 - - - Ald_Xan_dh_C,Ald_Xan_dh_C2 SJTD3_k127_7394742_1 164757.Mjls_4986 2.039e-62 218.0 COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,234GK@1762|Mycobacteriaceae 201174|Actinobacteria C 2Fe-2S -binding domain coxS - 1.2.5.3 ko:K03518 - - R11168 RC02800 ko00000,ko01000 - - - Fer2,Fer2_2 SJTD3_k127_7395733_0 118166.JH976537_gene1346 8.105e-160 521.0 COG5421@1|root,COG5421@2|Bacteria,1G4EU@1117|Cyanobacteria,1H9I9@1150|Oscillatoriales 1117|Cyanobacteria L IMG reference gene - - - - - - - - - - - - DDE_Tnp_1 SJTD3_k127_7413054_14 525904.Tter_0859 7.499e-35 142.0 COG2152@1|root,COG2152@2|Bacteria,2NPN0@2323|unclassified Bacteria 2|Bacteria G beta-1,4-mannooligosaccharide phosphorylase - - 2.4.1.339,2.4.1.340 ko:K20885 - - R11397,R11398 RC00049,RC02748 ko00000,ko01000 - GH130 - Glyco_hydro_130 SJTD3_k127_7413054_3 1499967.BAYZ01000038_gene2268 1.635e-126 415.0 COG3408@1|root,COG3408@2|Bacteria 2|Bacteria G Glycogen debranching enzyme - - - - - - - - - - - - DUF608,GDE_C,Glyco_hydro_100,S6PP SJTD3_k127_7413054_11 265729.GS18_0202250 9.507e-44 172.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli,1ZBS6@1386|Bacillus 91061|Bacilli K transcriptional yvoA - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA SJTD3_k127_7413054_13 33898.JRHJ01000079_gene1403 5.652e-39 167.0 COG1172@1|root,COG1879@1|root,COG1172@2|Bacteria,COG1879@2|Bacteria,2GJDW@201174|Actinobacteria 201174|Actinobacteria G Belongs to the binding-protein-dependent transport system permease family rbsC - - ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2,Peripla_BP_4 SJTD3_k127_7413054_1 632292.Calhy_0678 1.238e-129 433.0 COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,42FNU@68295|Thermoanaerobacterales 186801|Clostridia P Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system mglA - 3.6.3.17 ko:K10441 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - ABC_tran SJTD3_k127_7413054_7 887325.HMPREF0381_0745 5.652e-58 215.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,1HUGI@1164882|Lachnoanaerobaculum 186801|Clostridia G Branched-chain amino acid transport system / permease component - - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_7413054_10 592027.CLG_B0090 1.139e-51 195.0 COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,36DTM@31979|Clostridiaceae 186801|Clostridia G Belongs to the binding-protein-dependent transport system permease family rbsC - - ko:K10440 ko02010,map02010 M00212 - - ko00000,ko00001,ko00002,ko02000 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 - - BPD_transp_2 SJTD3_k127_7413054_6 1500304.JQKY01000002_gene4048 5.478e-64 234.0 COG0673@1|root,COG0673@2|Bacteria 2|Bacteria S inositol 2-dehydrogenase activity mviM - 1.1.1.18,1.1.1.369 ko:K00010,ko:K03810 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 - R01183,R09951 RC00182 ko00000,ko00001,ko01000 - - - GFO_IDH_MocA SJTD3_k127_7413054_5 928724.SacglDRAFT_04209 3.726e-93 319.0 COG4948@1|root,COG4948@2|Bacteria,2GT81@201174|Actinobacteria,4E06M@85010|Pseudonocardiales 201174|Actinobacteria M Mandelate racemase muconate lactonizing enzyme - - 4.2.1.6 ko:K01684 ko00052,ko01100,ko01120,map00052,map01100,map01120 M00552 R03033 RC00543 ko00000,ko00001,ko00002,ko01000 - - - MR_MLE_C,MR_MLE_N SJTD3_k127_7413054_9 903814.ELI_0531 2.864e-54 199.0 COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,25UZF@186806|Eubacteriaceae 186801|Clostridia G Class II Aldolase and Adducin N-terminal domain - - 4.1.2.17 ko:K01628 ko00051,ko01120,map00051,map01120 - R02262 RC00603,RC00604 ko00000,ko00001,ko01000 - - - Aldolase_II SJTD3_k127_7413054_4 266117.Rxyl_0532 3.112e-103 349.0 COG2017@1|root,COG2017@2|Bacteria,2IDCU@201174|Actinobacteria 201174|Actinobacteria G Domain of unknown function (DUF4432) - - - - - - - - - - - - DUF4432 SJTD3_k127_7413054_8 1210884.HG799474_gene15149 8.168e-58 213.0 COG0524@1|root,COG0524@2|Bacteria,2IWUH@203682|Planctomycetes 203682|Planctomycetes G pfkB family carbohydrate kinase - - 2.7.1.45 ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 M00061,M00308,M00631 R01541 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PfkB SJTD3_k127_7413054_12 1123242.JH636435_gene1078 4.181e-40 157.0 COG0800@1|root,COG0800@2|Bacteria,2IXBP@203682|Planctomycetes 203682|Planctomycetes G PFAM KDPG and KHG aldolase - - 4.1.2.14,4.1.3.42 ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 M00008,M00061,M00308,M00631 R00470,R05605 RC00307,RC00308,RC00435 ko00000,ko00001,ko00002,ko01000 - - - Aldolase SJTD3_k127_7413054_0 1234664.AMRO01000003_gene625 4.502e-188 611.0 COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,1TPIK@1239|Firmicutes,4HC6E@91061|Bacilli,1WHXR@129337|Geobacillus 91061|Bacilli IQ Enoyl-(Acyl carrier protein) reductase - - 1.3.1.28 ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 - R01505 RC00534 ko00000,ko00001,ko01000 - - - adh_short_C2 SJTD3_k127_7413054_2 525904.Tter_1240 9.164e-128 424.0 COG0124@1|root,COG0124@2|Bacteria,2NNZ7@2323|unclassified Bacteria 2|Bacteria J Histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His SJTD3_k127_7432249_1 420324.KI911972_gene3032 9.978e-21 93.0 COG0745@1|root,COG2114@1|root,COG0745@2|Bacteria,COG2114@2|Bacteria,1MV1V@1224|Proteobacteria,2U2BQ@28211|Alphaproteobacteria,1JYYS@119045|Methylobacteriaceae 28211|Alphaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - Guanylate_cyc,Response_reg SJTD3_k127_7432249_0 716928.AJQT01000103_gene1326 3.067e-99 340.0 COG0457@1|root,COG2114@1|root,COG5616@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG5616@2|Bacteria,1MUMZ@1224|Proteobacteria,2TRUI@28211|Alphaproteobacteria,4B9BA@82115|Rhizobiaceae 28211|Alphaproteobacteria T Adenylate cyclase - - - - - - - - - - - - Guanylate_cyc,TPR_16,TPR_2,TPR_8 SJTD3_k127_7438937_2 376733.IT41_05470 1.299e-19 87.0 COG1028@1|root,COG1028@2|Bacteria,1MUPX@1224|Proteobacteria,2V7Q9@28211|Alphaproteobacteria,2PYRE@265|Paracoccus 28211|Alphaproteobacteria IQ KR domain - - - - - - - - - - - - adh_short_C2 SJTD3_k127_7438937_0 383372.Rcas_3820 1.794e-104 364.0 COG2304@1|root,COG2304@2|Bacteria,2GABP@200795|Chloroflexi,37510@32061|Chloroflexia 32061|Chloroflexia S von Willebrand factor, type A - - - - - - - - - - - - BatA,VWA_2 SJTD3_k127_7438937_1 670487.Ocepr_0787 1.949e-31 128.0 COG3294@1|root,COG3294@2|Bacteria,1WJ8W@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus S Metal dependent phosphohydrolases with conserved 'HD' motif. - - - ko:K09163 - - - - ko00000 - - - HD SJTD3_k127_7448578_0 1128421.JAGA01000002_gene905 1.031e-155 504.0 COG2230@1|root,COG2230@2|Bacteria 2|Bacteria M cyclopropane-fatty-acyl-phospholipid synthase - - 2.1.1.79 ko:K00574 - - - - ko00000,ko01000 - - iAF987.Gmet_2187 CMAS SJTD3_k127_7448578_3 345341.KUTG_03463 1.615e-09 66.0 COG1514@1|root,COG1514@2|Bacteria,2IKSA@201174|Actinobacteria,4E66X@85010|Pseudonocardiales 201174|Actinobacteria J 2'-5' RNA ligase superfamily - - - - - - - - - - - - 2_5_RNA_ligase2 SJTD3_k127_7448578_1 1128421.JAGA01000002_gene285 2.646e-74 266.0 COG0859@1|root,COG0859@2|Bacteria,2NP5P@2323|unclassified Bacteria 2|Bacteria M Glycosyl transferase, family 9 - - - ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 M00080 - - ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 - GT9 - Glyco_transf_9 SJTD3_k127_7448578_2 398511.BpOF4_13365 1.358e-19 92.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli,1ZB7J@1386|Bacillus 91061|Bacilli J Methylates ribosomal protein L11 prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA SJTD3_k127_745385_2 479434.Sthe_1978 5.203e-18 89.0 COG1807@1|root,COG1807@2|Bacteria,2G8QS@200795|Chloroflexi 200795|Chloroflexi M Dolichyl-phosphate-mannose-protein mannosyltransferase - - - - - - - - - - - - PMT_2 SJTD3_k127_745385_1 744872.Spica_1697 1.949e-54 198.0 COG0290@1|root,COG0290@2|Bacteria,2J76T@203691|Spirochaetes 203691|Spirochaetes J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC - - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N SJTD3_k127_745385_0 515635.Dtur_1563 1.341e-247 782.0 COG0495@1|root,COG0495@2|Bacteria 2|Bacteria J leucyl-tRNA aminoacylation leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_2300 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 SJTD3_k127_7455173_2 1128421.JAGA01000004_gene2627 8.631e-27 111.0 COG0836@1|root,COG0836@2|Bacteria,2NP3C@2323|unclassified Bacteria 2|Bacteria M Mannose-6-phosphate isomerase manC - 2.7.7.13,5.3.1.8 ko:K00971,ko:K16011 ko00051,ko00520,ko01100,ko01110,ko01130,ko02025,map00051,map00520,map01100,map01110,map01130,map02025 M00114,M00361,M00362 R00885,R01819 RC00002,RC00376 ko00000,ko00001,ko00002,ko01000 - - - MannoseP_isomer,NTP_transferase SJTD3_k127_7455173_0 1128421.JAGA01000001_gene2275 2.736e-105 352.0 COG1482@1|root,COG1482@2|Bacteria,2NR16@2323|unclassified Bacteria 2|Bacteria G Phosphomannose isomerase type I manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - - PMI_typeI SJTD3_k127_7455173_1 926569.ANT_19760 1.939e-66 236.0 COG2267@1|root,COG2267@2|Bacteria,2G6KF@200795|Chloroflexi 200795|Chloroflexi I Alpha beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_4,Abhydrolase_6 SJTD3_k127_7463636_1 448385.sce5828 1.046e-41 166.0 COG0644@1|root,COG0644@2|Bacteria,1MXQY@1224|Proteobacteria,42UR3@68525|delta/epsilon subdivisions 1224|Proteobacteria C TIGRFAM geranylgeranyl reductase - - 1.3.1.111,1.3.1.83 ko:K10960 ko00860,ko00900,ko01100,ko01110,map00860,map00900,map01100,map01110 - R02063,R08754,R08755,R08756,R11226,R11518 RC00212,RC00522,RC01823 ko00000,ko00001,ko01000 - - - FAD_binding_3,FAD_oxidored SJTD3_k127_7463636_0 1382356.JQMP01000001_gene1263 9.599e-83 282.0 COG1028@1|root,COG1028@2|Bacteria,2G8II@200795|Chloroflexi,27XKN@189775|Thermomicrobia 189775|Thermomicrobia IQ Dehydrogenase reductase sdr - - 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - - adh_short_C2 SJTD3_k127_7480272_1 926550.CLDAP_40290 1.662e-154 496.0 COG0399@1|root,COG0399@2|Bacteria,2G7XI@200795|Chloroflexi 200795|Chloroflexi E DegT/DnrJ/EryC1/StrS aminotransferase family - - - - - - - - - - - - DegT_DnrJ_EryC1 SJTD3_k127_7480272_0 1173024.KI912148_gene3138 8.037e-202 649.0 COG1086@1|root,COG1086@2|Bacteria,1G18C@1117|Cyanobacteria,1JKBP@1189|Stigonemataceae 1117|Cyanobacteria M CoA-binding domain - - - - - - - - - - - - CoA_binding_3,EAL,Polysacc_synt_2 SJTD3_k127_7495607_3 401053.AciPR4_0922 3.413e-09 61.0 COG0697@1|root,COG0697@2|Bacteria,3Y8GX@57723|Acidobacteria 57723|Acidobacteria EG EamA-like transporter family - - - - - - - - - - - - EamA SJTD3_k127_7495607_0 1185876.BN8_01879 2.219e-91 313.0 COG3214@1|root,COG3214@2|Bacteria,4NGF2@976|Bacteroidetes,47MWM@768503|Cytophagia 976|Bacteroidetes S Winged helix DNA-binding domain - - - - - - - - - - - - HTH_42 SJTD3_k127_7495607_1 251221.35214034 6.22e-49 180.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - - - - - - - - - - Acetyltransf_3 SJTD3_k127_7495607_2 1227352.C173_05256 8.012e-29 118.0 COG1359@1|root,COG1359@2|Bacteria,1VF3R@1239|Firmicutes,4HPSA@91061|Bacilli,26YA3@186822|Paenibacillaceae 91061|Bacilli S Antibiotic biosynthesis monooxygenase - - - - - - - - - - - - ABM SJTD3_k127_7498495_0 316274.Haur_3632 3.418e-101 343.0 COG0646@1|root,COG0685@1|root,COG0646@2|Bacteria,COG0685@2|Bacteria 2|Bacteria E methylenetetrahydrofolate reductase (NAD(P)H) activity yitJ - 1.5.1.20,2.1.1.10,2.1.1.13 ko:K00297,ko:K00547,ko:K00548 ko00270,ko00450,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01230,ko01523,map00270,map00450,map00670,map00720,map01100,map01110,map01120,map01200,map01230,map01523 M00017,M00377 R00650,R00946,R01224,R07168,R09365 RC00003,RC00035,RC00081,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - iAF987.Gmet_0504 MTHFR,S-methyl_trans SJTD3_k127_7498572_1 696369.KI912183_gene2390 8.664e-43 162.0 COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,260RP@186807|Peptococcaceae 186801|Clostridia F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis coaX - 2.7.1.33 ko:K03525 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - Pan_kinase SJTD3_k127_7498572_2 446470.Snas_3453 7.782e-05 53.0 2E0MB@1|root,32W6J@2|Bacteria,2IR53@201174|Actinobacteria 201174|Actinobacteria - - - - - - - - - - - - - - - SJTD3_k127_7498572_0 383372.Rcas_0333 1.573e-73 252.0 COG0414@1|root,COG0414@2|Bacteria,2G64N@200795|Chloroflexi,374TX@32061|Chloroflexia 32061|Chloroflexia H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate panC GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 M00119 R02473 RC00096,RC00141 ko00000,ko00001,ko00002,ko01000 - - - Pantoate_ligase SJTD3_k127_7506370_1 1123024.AUII01000001_gene3015 1.05e-31 142.0 COG2244@1|root,COG2244@2|Bacteria,2IF43@201174|Actinobacteria 201174|Actinobacteria S polysaccharide biosynthetic process - - - - - - - - - - - - Polysacc_synt SJTD3_k127_7506370_0 316274.Haur_0043 4.543e-56 210.0 COG1216@1|root,COG1216@2|Bacteria 2|Bacteria V Glycosyl transferase, family 2 - - - - - - - - - - - - Glycos_transf_2 SJTD3_k127_7506370_2 326424.FRAAL6117 9.643e-12 71.0 COG1216@1|root,COG1216@2|Bacteria,2GKTW@201174|Actinobacteria,4ETWP@85013|Frankiales 201174|Actinobacteria S Glycosyltransferase like family 2 - - - - - - - - - - - - Glyco_tranf_2_3,Glyco_transf_7C,Glycos_transf_2 SJTD3_k127_7518812_1 765420.OSCT_2099 2.47e-23 115.0 COG1287@1|root,COG1287@2|Bacteria,2GBKX@200795|Chloroflexi,3781U@32061|Chloroflexia 32061|Chloroflexia S oligosaccharyl transferase activity - - - - - - - - - - - - - SJTD3_k127_7518812_0 608506.COB47_1144 1.211e-182 579.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,42F4M@68295|Thermoanaerobacterales 186801|Clostridia J Catalyzes the attachment of glycine to tRNA(Gly) glyQS GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 ko:K01880 ko00970,map00970 M00359,M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - HGTP_anticodon,tRNA-synt_2b SJTD3_k127_7523173_0 479434.Sthe_2682 3.685e-49 192.0 COG2265@1|root,COG2265@2|Bacteria,2G6IV@200795|Chloroflexi,27XG5@189775|Thermomicrobia 189775|Thermomicrobia J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr SJTD3_k127_7523173_4 1235755.ANAM01000001_gene61 2.116e-20 93.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli,4GZCE@90964|Staphylococcaceae 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 SJTD3_k127_7523173_1 316274.Haur_4963 2.854e-45 168.0 COG0629@1|root,COG0629@2|Bacteria,2G6YE@200795|Chloroflexi,375QY@32061|Chloroflexia 32061|Chloroflexia L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism - - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB SJTD3_k127_7523173_3 525904.Tter_0780 9.526e-28 118.0 COG0238@1|root,COG0238@2|Bacteria,2NQ53@2323|unclassified Bacteria 2|Bacteria J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963,ko:K03111,ko:K15125 ko03010,ko03030,ko03430,ko03440,ko05133,map03010,map03030,map03430,map03440,map05133 M00178 - - br01610,ko00000,ko00001,ko00002,ko00536,ko03011,ko03029,ko03032,ko03400 - - - Ribosomal_S18 SJTD3_k127_7523173_2 479434.Sthe_1448 1.205e-40 169.0 COG0760@1|root,COG0760@2|Bacteria,2G6RV@200795|Chloroflexi,27XG1@189775|Thermomicrobia 189775|Thermomicrobia O SurA N-terminal domain - - - - - - - - - - - - Rotamase_3 SJTD3_k127_7548776_2 1382356.JQMP01000003_gene1374 1.009e-20 98.0 COG2373@1|root,COG2373@2|Bacteria,2GBHR@200795|Chloroflexi,27YXZ@189775|Thermomicrobia 189775|Thermomicrobia P alginic acid biosynthetic process - - - - - - - - - - - - - SJTD3_k127_7548776_0 1001240.GY21_19065 1.251e-154 495.0 COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4FK6G@85023|Microbacteriaceae 201174|Actinobacteria E Zinc-binding dehydrogenase - - - - - - - - - - - - ADH_N,ADH_N_assoc,ADH_zinc_N SJTD3_k127_7548776_1 1121957.ATVL01000012_gene714 6.98e-35 136.0 COG0154@1|root,COG0154@2|Bacteria,4NF8C@976|Bacteroidetes,47MMB@768503|Cytophagia 976|Bacteroidetes J Amidase gatA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase SJTD3_k127_7556575_0 1101195.Meth11DRAFT_0144 1.6e-71 261.0 2CG4C@1|root,2Z8MQ@2|Bacteria,1R6PQ@1224|Proteobacteria,2VHKG@28216|Betaproteobacteria,2KKMA@206350|Nitrosomonadales 206350|Nitrosomonadales - - - - - - - - - - - - - - - SJTD3_k127_7556575_1 1236959.BAMT01000006_gene247 9.322e-70 241.0 COG1459@1|root,COG1459@2|Bacteria,1MV4U@1224|Proteobacteria,2VI1J@28216|Betaproteobacteria,2KKSQ@206350|Nitrosomonadales 206350|Nitrosomonadales NU PFAM type II secretion system - - - ko:K02653 - - - - ko00000,ko02035,ko02044 3.A.15.2 - - T2SSF SJTD3_k127_7584899_2 340099.Teth39_0866 6.624e-35 136.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,42GJ3@68295|Thermoanaerobacterales 186801|Clostridia J PFAM Endoribonuclease L-PSP yjgF - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP SJTD3_k127_7584899_0 1283300.ATXB01000002_gene2998 2.01e-58 212.0 COG0647@1|root,COG0647@2|Bacteria,1QGX4@1224|Proteobacteria,1RRS1@1236|Gammaproteobacteria,1XE4Z@135618|Methylococcales 135618|Methylococcales G Belongs to the HAD-like hydrolase superfamily - - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like SJTD3_k127_7584899_1 56107.Cylst_4383 6.932e-44 166.0 2BZ5C@1|root,33RFU@2|Bacteria,1GNQZ@1117|Cyanobacteria,1HRUW@1161|Nostocales 1117|Cyanobacteria - - - - - - - - - - - - - - - SJTD3_k127_7584899_3 1122609.AUGT01000010_gene3667 1.147e-09 59.0 2BZ5C@1|root,33RFU@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_758682_0 1128421.JAGA01000003_gene3259 3.14e-71 248.0 COG2197@1|root,COG2197@2|Bacteria,2NR2Y@2323|unclassified Bacteria 2|Bacteria T helix_turn_helix, Lux Regulon yhcZ - - ko:K02479 - - - - ko00000,ko02022 - - - GerE,Response_reg SJTD3_k127_758682_2 526227.Mesil_2815 2.342e-31 132.0 COG0344@1|root,COG0344@2|Bacteria,1WJ35@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf SJTD3_k127_758682_1 926569.ANT_06960 3.554e-36 143.0 COG1131@1|root,COG1131@2|Bacteria 2|Bacteria V ATPase activity - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 SJTD3_k127_760023_1 1121924.ATWH01000006_gene1965 8.567e-21 94.0 COG1619@1|root,COG1619@2|Bacteria,2GNW5@201174|Actinobacteria,4FPA7@85023|Microbacteriaceae 201174|Actinobacteria V LD-carboxypeptidase - - 3.4.17.13 ko:K01297 - - - - ko00000,ko01000,ko01002,ko01011 - - - Peptidase_S66 SJTD3_k127_760023_0 1229172.JQFA01000002_gene3355 4.382e-117 385.0 COG0053@1|root,COG0053@2|Bacteria,1G0RT@1117|Cyanobacteria,1HETU@1150|Oscillatoriales 1117|Cyanobacteria P Dimerisation domain of Zinc Transporter - - - - - - - - - - - - Cation_efflux,ZT_dimer SJTD3_k127_760023_2 1536774.H70357_03955 9.558e-13 73.0 COG4709@1|root,COG4709@2|Bacteria,1VE8I@1239|Firmicutes,4HN2C@91061|Bacilli,26Y07@186822|Paenibacillaceae 91061|Bacilli S membrane - - - - - - - - - - - - DUF1700 SJTD3_k127_7625962_0 309799.DICTH_1454 6.779e-86 289.0 COG0495@1|root,COG0495@2|Bacteria 2|Bacteria J leucyl-tRNA aminoacylation leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - iAF987.Gmet_2300 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 SJTD3_k127_7625962_2 1463841.JOIR01000027_gene827 3.59e-10 72.0 COG2340@1|root,COG2340@2|Bacteria,2I39U@201174|Actinobacteria 201174|Actinobacteria S Cysteine-rich secretory protein family - - - - - - - - - - - - CAP SJTD3_k127_7625962_1 485913.Krac_6152 4.27e-17 85.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_C_8,TetR_N SJTD3_k127_7628065_1 525146.Ddes_1880 7.982e-05 55.0 COG0651@1|root,COG0651@2|Bacteria,1QU5Z@1224|Proteobacteria,42MDX@68525|delta/epsilon subdivisions,2WJ56@28221|Deltaproteobacteria,2M8BF@213115|Desulfovibrionales 28221|Deltaproteobacteria CP PFAM NADH Ubiquinone plastoquinone (complex I) - - - - - - - - - - - - Proton_antipo_M,Proton_antipo_N SJTD3_k127_7628065_0 1218074.BAXZ01000017_gene3531 4.031e-07 58.0 COG1143@1|root,COG3260@1|root,COG1143@2|Bacteria,COG3260@2|Bacteria,1QUBE@1224|Proteobacteria,2W1TW@28216|Betaproteobacteria,1KH8J@119060|Burkholderiaceae 28216|Betaproteobacteria C NADH ubiquinone oxidoreductase, 20 Kd subunit - - - - - - - - - - - - Fer4,Fer4_6,Fer4_7,Oxidored_q6 SJTD3_k127_7646379_0 867903.ThesuDRAFT_02243 5.45e-54 200.0 COG1290@1|root,COG1290@2|Bacteria,1USWS@1239|Firmicutes,2501X@186801|Clostridia 186801|Clostridia C Cytochrome b(C-terminal)/b6/petD - - - - - - - - - - - - Cytochrom_B_C SJTD3_k127_7646379_1 644966.Tmar_0323 3.84e-49 181.0 COG0723@1|root,COG0723@2|Bacteria,1VM4K@1239|Firmicutes,24X5X@186801|Clostridia 186801|Clostridia C PFAM Rieske 2Fe-2S domain - - 1.10.9.1 ko:K02636 ko00195,ko01100,map00195,map01100 M00162 R03817,R08409 RC01002 ko00000,ko00001,ko00002,ko00194,ko01000 - - - Rieske SJTD3_k127_7646379_2 867903.ThesuDRAFT_02246 4.042e-32 138.0 COG2010@1|root,COG2010@2|Bacteria,1VX6C@1239|Firmicutes,251IR@186801|Clostridia 186801|Clostridia C Cytochrome C oxidase, cbb3-type, subunit III - - - - - - - - - - - - Cytochrom_C SJTD3_k127_7646379_3 410359.Pcal_1905 7.719e-05 51.0 arCOG04198@1|root,arCOG04198@2157|Archaea 2157|Archaea S Ethylbenzene dehydrogenase - - - ko:K17052 - - - - ko00000,ko02000 5.A.3.8 - - EB_dh SJTD3_k127_7684897_2 518766.Rmar_0382 2.137e-08 56.0 COG0572@1|root,COG0572@2|Bacteria,4NEEC@976|Bacteroidetes,1FIYA@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes F Phosphoribulokinase / Uridine kinase family udk - 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK SJTD3_k127_7684897_0 479434.Sthe_0904 1.719e-71 257.0 COG0438@1|root,COG0438@2|Bacteria,2G5PS@200795|Chloroflexi,27XVU@189775|Thermomicrobia 189775|Thermomicrobia M Glycosyl transferase 4-like domain - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_7684897_1 1077144.AGFF01000003_gene2417 9.092e-09 63.0 COG3307@1|root,COG3307@2|Bacteria 2|Bacteria M -O-antigen - - - - - - - - - - - - Wzy_C SJTD3_k127_7692730_0 1463921.JODF01000002_gene3096 4.223e-141 484.0 COG2319@1|root,COG2319@2|Bacteria,2GJN3@201174|Actinobacteria 201174|Actinobacteria F WD-40 repeat - - - - - - - - - - - - HTH_31,WD40 SJTD3_k127_7692730_4 35754.JNYJ01000019_gene80 6.612e-08 66.0 COG1396@1|root,COG3903@1|root,COG1396@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DH3V@85008|Micromonosporales 201174|Actinobacteria KT Transcriptional regulator - - - - - - - - - - - - AAA_22,BTAD,DUF4062,HTH_31,NB-ARC,TPR_12 SJTD3_k127_7692730_3 1430331.EP10_15410 3.735e-10 64.0 COG2197@1|root,COG2197@2|Bacteria,1TRXG@1239|Firmicutes,4HA3V@91061|Bacilli,1WE7Q@129337|Geobacillus 91061|Bacilli K helix_turn_helix, Lux Regulon degU - - ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 M00478 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg SJTD3_k127_7692730_2 717605.Theco_0138 7.458e-57 210.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli,26RZN@186822|Paenibacillaceae 91061|Bacilli S Metal-dependent hydrolases of the beta-lactamase superfamily I vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 SJTD3_k127_7692730_1 326427.Cagg_1059 3.817e-130 424.0 COG0477@1|root,COG2814@2|Bacteria,2G7PX@200795|Chloroflexi,3765F@32061|Chloroflexia 32061|Chloroflexia EGP Major Facilitator Superfamily - - - - - - - - - - - - MFS_1 SJTD3_k127_7699707_0 326427.Cagg_1321 1.15e-137 456.0 COG1574@1|root,COG1574@2|Bacteria,2G5YJ@200795|Chloroflexi,375CQ@32061|Chloroflexia 32061|Chloroflexia S PFAM Amidohydrolase 3 - - - - - - - - - - - - Amidohydro_3 SJTD3_k127_7699707_1 1242864.D187_005544 2.738e-78 276.0 COG1819@1|root,COG1819@2|Bacteria,1PVC0@1224|Proteobacteria,434ZI@68525|delta/epsilon subdivisions,2WZAA@28221|Deltaproteobacteria,2Z1PJ@29|Myxococcales 28221|Deltaproteobacteria CG UDP-glucoronosyl and UDP-glucosyl transferase - - - - - - - - - - - - UDPGT SJTD3_k127_7699707_2 1227488.C477_01530 2.522e-43 169.0 COG0596@1|root,arCOG01648@2157|Archaea,2XW5K@28890|Euryarchaeota,23TTR@183963|Halobacteria 183963|Halobacteria S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_6 SJTD3_k127_7699707_3 134676.ACPL_6640 4.472e-08 63.0 COG0823@1|root,COG0823@2|Bacteria,2IK6C@201174|Actinobacteria,4DDBC@85008|Micromonosporales 201174|Actinobacteria U WD40-like Beta Propeller Repeat tolB - - ko:K03641 - - - - ko00000,ko02000 2.C.1.2 - - PD40 SJTD3_k127_7746453_6 326427.Cagg_1257 1.198e-05 55.0 COG3170@1|root,COG3170@2|Bacteria,2GBRC@200795|Chloroflexi,375MT@32061|Chloroflexia 32061|Chloroflexia NU Type IV pilus biogenesis stability protein PilW - - - - - - - - - - - - - SJTD3_k127_7746453_2 326427.Cagg_1923 4.441e-32 128.0 COG0799@1|root,COG0799@2|Bacteria,2G77A@200795|Chloroflexi,375T8@32061|Chloroflexia 32061|Chloroflexia J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS - - ko:K09710 - - - - ko00000,ko03009 - - - RsfS SJTD3_k127_7746453_4 368407.Memar_0896 5.619e-19 96.0 COG4912@1|root,arCOG05122@2157|Archaea,2XWYV@28890|Euryarchaeota,2N9IE@224756|Methanomicrobia 224756|Methanomicrobia L PFAM DNA alkylation repair enzyme - - - - - - - - - - - - DNA_alkylation SJTD3_k127_7746453_3 479434.Sthe_1281 1.366e-24 109.0 COG2331@1|root,COG2331@2|Bacteria,2G795@200795|Chloroflexi,27YPR@189775|Thermomicrobia 189775|Thermomicrobia S Regulatory protein, FmdB family - - - - - - - - - - - - Zn-ribbon_8 SJTD3_k127_7746453_1 1476583.DEIPH_ctg050orf0040 5.746e-51 184.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein - - - - - - - - - - - - OsmC,TusA SJTD3_k127_7746453_0 479434.Sthe_0669 1.598e-59 217.0 COG0249@1|root,COG0249@2|Bacteria,2G5IU@200795|Chloroflexi,27XRG@189775|Thermomicrobia 189775|Thermomicrobia L that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V SJTD3_k127_7751322_0 357808.RoseRS_2630 1.142e-148 501.0 COG1874@1|root,COG1874@2|Bacteria,2GBMG@200795|Chloroflexi,376H5@32061|Chloroflexia 32061|Chloroflexia G Flagellar filament outer layer protein Flaa - - - - - - - - - - - - Glyco_hydro_42,Glyco_hydro_cc SJTD3_k127_7788675_2 357808.RoseRS_0947 2.707e-11 70.0 COG3025@1|root,COG5607@1|root,COG3025@2|Bacteria,COG5607@2|Bacteria,2G7FA@200795|Chloroflexi,375SS@32061|Chloroflexia 32061|Chloroflexia FP PFAM CHAD domain containing protein - - - - - - - - - - - - CHAD,CYTH,HD SJTD3_k127_7788675_1 357808.RoseRS_0390 1.509e-59 216.0 COG0345@1|root,COG0345@2|Bacteria,2G5QD@200795|Chloroflexi,375AU@32061|Chloroflexia 32061|Chloroflexia E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer SJTD3_k127_7788675_0 1382306.JNIM01000001_gene3777 1.357e-118 400.0 COG2303@1|root,COG2303@2|Bacteria,2G7EB@200795|Chloroflexi 200795|Chloroflexi E GMC oxidoreductase - - - - - - - - - - - - GMC_oxred_C,GMC_oxred_N SJTD3_k127_7805828_2 1385518.N798_17385 3.189e-13 80.0 COG2755@1|root,COG2755@2|Bacteria,2IC8X@201174|Actinobacteria,4FI2P@85021|Intrasporangiaceae 201174|Actinobacteria E GDSL-like Lipase/Acylhydrolase family - - - - - - - - - - - - Lipase_GDSL_2 SJTD3_k127_7805828_4 1382304.JNIL01000001_gene352 1.333e-08 61.0 COG1813@1|root,COG1813@2|Bacteria,1VEVE@1239|Firmicutes,4HSD1@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 SJTD3_k127_7805828_3 102125.Xen7305DRAFT_00031880 6.398e-11 74.0 COG4712@1|root,COG4712@2|Bacteria,1GEA7@1117|Cyanobacteria 1117|Cyanobacteria S double-strand break repair protein - - - - - - - - - - - - DUF1071 SJTD3_k127_7805828_0 555778.Hneap_2334 1.485e-19 104.0 COG1475@1|root,COG1475@2|Bacteria,1MW2E@1224|Proteobacteria,1RN65@1236|Gammaproteobacteria,1WWNZ@135613|Chromatiales 135613|Chromatiales K Belongs to the ParB family - - - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - ParBc SJTD3_k127_780677_1 479433.Caci_2294 6.982e-07 56.0 COG2197@1|root,COG2197@2|Bacteria,2I91X@201174|Actinobacteria 201174|Actinobacteria K helix_turn_helix, Lux Regulon - - - - - - - - - - - - GerE SJTD3_k127_780677_0 1340493.JNIF01000003_gene1505 1.612e-64 227.0 2F2X8@1|root,33VSU@2|Bacteria,3Y7XB@57723|Acidobacteria 57723|Acidobacteria - - - - - - - - - - - - - - - SJTD3_k127_7810947_1 562970.Btus_0636 3.466e-80 275.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,4HBVG@91061|Bacilli,277ZQ@186823|Alicyclobacillaceae 91061|Bacilli C SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 sdhA - 1.3.5.1,1.3.5.4 ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - FAD_binding_2,Succ_DH_flav_C SJTD3_k127_7810947_0 649747.HMPREF0083_03737 6.407e-106 350.0 COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,4HAG7@91061|Bacilli,26T71@186822|Paenibacillaceae 91061|Bacilli C SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 sdhB - 1.3.5.1,1.3.5.4 ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00149,M00173,M00374,M00376 R02164 RC00045 ko00000,ko00001,ko00002,ko01000 - - - Fer2_3,Fer4_8 SJTD3_k127_7810947_2 59538.XP_005979423.1 0.0003855 43.0 COG0277@1|root,KOG1231@2759|Eukaryota,38FXH@33154|Opisthokonta,3BEEV@33208|Metazoa,3CRTP@33213|Bilateria,4801S@7711|Chordata,492UT@7742|Vertebrata,3JDRF@40674|Mammalia,4J43Y@91561|Cetartiodactyla 33208|Metazoa C dehydrogenase - - - - - - - - - - - - FAD-oxidase_C,FAD_binding_4,Fer4_8 SJTD3_k127_7831395_1 247490.KSU1_C0433 1.583e-20 94.0 COG0125@1|root,COG0125@2|Bacteria,2J2WW@203682|Planctomycetes 203682|Planctomycetes F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - - - - - - - - - - - SJTD3_k127_7831395_0 349124.Hhal_0770 2.19e-28 125.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 SJTD3_k127_7832343_1 706587.Desti_2023 3.01e-120 398.0 COG0477@1|root,COG0477@2|Bacteria,1MXZ3@1224|Proteobacteria,43BMH@68525|delta/epsilon subdivisions,2WPN9@28221|Deltaproteobacteria,2MRFR@213462|Syntrophobacterales 28221|Deltaproteobacteria EGP Transmembrane secretion effector - - - - - - - - - - - - MFS_3 SJTD3_k127_7832343_2 457425.XNR_5073 9.675e-18 96.0 COG5542@1|root,COG5542@2|Bacteria,2GJQF@201174|Actinobacteria 201174|Actinobacteria NT integral membrane protein - - - - - - - - - - - - Mannosyl_trans2,PMT_2 SJTD3_k127_7832343_0 525904.Tter_0051 2.882e-277 865.0 COG0187@1|root,COG0187@2|Bacteria,2NNSN@2323|unclassified Bacteria 2|Bacteria L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim SJTD3_k127_7832343_3 580340.Tlie_0303 1.521e-17 88.0 COG3415@1|root,COG3415@2|Bacteria 2|Bacteria L Transposase - - - ko:K07497 - - - - ko00000 - - - HTH_23,HTH_28,HTH_29,Mu-transpos_C,rve SJTD3_k127_80600_1 1303518.CCALI_00648 7.002e-31 130.0 COG2802@1|root,COG2802@2|Bacteria 2|Bacteria S histone H2A-K13 ubiquitination lonD - 3.4.21.53 ko:K01338,ko:K07157 ko04112,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - LON_substr_bdg SJTD3_k127_80600_2 926560.KE387025_gene4050 9.022e-14 79.0 COG1796@1|root,COG1796@2|Bacteria 2|Bacteria L DNA-directed DNA polymerase activity dpbF - 3.1.11.5 ko:K02347,ko:K03581,ko:K04477 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,HHH_8 SJTD3_k127_80600_0 1128421.JAGA01000002_gene1350 9.775e-54 205.0 COG1807@1|root,COG1807@2|Bacteria 2|Bacteria M 4-amino-4-deoxy-L-arabinose transferase activity - - - - - - - - - - - - PMT_2 SJTD3_k127_83801_0 525904.Tter_1349 6.581e-215 677.0 COG0542@1|root,COG0542@2|Bacteria,2NNKN@2323|unclassified Bacteria 2|Bacteria O C-terminal, D2-small domain, of ClpB protein clpC GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR SJTD3_k127_83801_1 326427.Cagg_1002 1.931e-54 216.0 COG5617@1|root,COG5617@2|Bacteria 2|Bacteria M Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - SJTD3_k127_842528_0 357808.RoseRS_2358 2.664e-63 236.0 COG1525@1|root,COG1572@1|root,COG1525@2|Bacteria,COG1572@2|Bacteria,2G86R@200795|Chloroflexi,3757A@32061|Chloroflexia 32061|Chloroflexia G PFAM peptidase domain protein - - - - - - - - - - - - NPCBM_assoc,PPC SJTD3_k127_85037_0 1521187.JPIM01000075_gene2832 3.489e-48 192.0 2EWUK@1|root,33Q65@2|Bacteria,2GAC8@200795|Chloroflexi,3755J@32061|Chloroflexia 32061|Chloroflexia - - - - - - - - - - - - - - Peptidase_MA_2 SJTD3_k127_85037_1 1463854.JOHT01000015_gene5316 2.414e-05 55.0 COG0454@1|root,COG0456@2|Bacteria,2GMXI@201174|Actinobacteria 201174|Actinobacteria K Histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1 SJTD3_k127_864230_1 485913.Krac_2926 3.589e-123 424.0 COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2G7W3@200795|Chloroflexi 200795|Chloroflexi K transcriptional regulator, LuxR family - - - - - - - - - - - - AAA_22,GerE,NB-ARC,TPR_12 SJTD3_k127_864230_0 439235.Dalk_1526 9.293e-141 492.0 COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,42NXT@68525|delta/epsilon subdivisions,2WIZ3@28221|Deltaproteobacteria,2MKIU@213118|Desulfobacterales 28221|Deltaproteobacteria T Adenylyl- / guanylyl cyclase, catalytic domain - - - - - - - - - - - - AAA_16,DZR,Guanylate_cyc,Pkinase,TPR_12 SJTD3_k127_864230_2 1174528.JH992893_gene5965 3.529e-11 66.0 COG0492@1|root,COG3437@1|root,COG0492@2|Bacteria,COG3437@2|Bacteria,1FZX5@1117|Cyanobacteria,1JK99@1189|Stigonemataceae 1117|Cyanobacteria KOT Pyridine nucleotide-disulphide oxidoreductase - - - - - - - - - - - - Pyr_redox_2,Response_reg SJTD3_k127_888114_0 1382306.JNIM01000001_gene2851 4.078e-112 368.0 COG2719@1|root,COG2719@2|Bacteria,2G5PX@200795|Chloroflexi 200795|Chloroflexi S SpoVR like protein - - - ko:K06415 - - - - ko00000 - - - SpoVR SJTD3_k127_888114_2 1137799.GZ78_26080 3.075e-10 70.0 2EJ2Y@1|root,33CU5@2|Bacteria,1P8PD@1224|Proteobacteria,1STSF@1236|Gammaproteobacteria 1236|Gammaproteobacteria - - - - - - - - - - - - - - - SJTD3_k127_888114_1 525904.Tter_1034 9.157e-14 77.0 2ESS5@1|root,33KAI@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_888114_3 309801.trd_1498 0.000842 46.0 2B6U1@1|root,31ZTE@2|Bacteria,2GBBT@200795|Chloroflexi,27YPW@189775|Thermomicrobia 189775|Thermomicrobia - - - - - - - - - - - - - - - SJTD3_k127_938417_4 485913.Krac_7315 6.99e-37 142.0 2EBEI@1|root,335F5@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_938417_1 525904.Tter_0670 2.442e-120 395.0 COG2141@1|root,COG2141@2|Bacteria 2|Bacteria C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - Bac_luciferase SJTD3_k127_938417_0 518766.Rmar_0950 2.988e-151 488.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,1FJVB@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Belongs to the argininosuccinate synthase family. Type 1 subfamily argG - 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - - Arginosuc_synth SJTD3_k127_938417_2 518766.Rmar_0949 1.748e-86 298.0 COG1763@1|root,COG1763@2|Bacteria,4PM6G@976|Bacteroidetes,1FK05@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Mo-molybdopterin cofactor biosynthetic process - - - - - - - - - - - - - SJTD3_k127_938417_3 1121468.AUBR01000019_gene2618 5.321e-79 288.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,42F2M@68295|Thermoanaerobacterales 186801|Clostridia E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC - 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC SJTD3_k127_938417_5 518766.Rmar_0947 7.967e-35 136.0 COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,1FJWU@1100069|Bacteroidetes Order II. Incertae sedis 976|Bacteroidetes H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 SJTD3_k127_942758_2 525904.Tter_1376 6.104e-78 278.0 COG0768@1|root,COG0768@2|Bacteria,2NQV0@2323|unclassified Bacteria 2|Bacteria M Penicillin binding protein transpeptidase domain pbpA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K05364 ko00550,map00550 - R04519 RC00005,RC00049 ko00000,ko00001,ko01011 - - - Transpeptidase SJTD3_k127_942758_0 479434.Sthe_1162 1.184e-126 423.0 COG0772@1|root,COG0772@2|Bacteria,2G6NR@200795|Chloroflexi,27Y4C@189775|Thermomicrobia 189775|Thermomicrobia D Cell cycle protein - - - - - - - - - - - - FTSW_RODA_SPOVE SJTD3_k127_942758_1 479434.Sthe_1161 4.085e-105 349.0 COG0005@1|root,COG0005@2|Bacteria,2G5JP@200795|Chloroflexi,27Y3U@189775|Thermomicrobia 189775|Thermomicrobia F Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates - - 2.4.2.28 ko:K00772 ko00270,ko01100,map00270,map01100 M00034 R01402 RC00063,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 SJTD3_k127_942758_4 497321.C664_16008 3.244e-42 159.0 COG1832@1|root,COG1832@2|Bacteria,1N03D@1224|Proteobacteria,2VU9G@28216|Betaproteobacteria,2KWFV@206389|Rhodocyclales 206389|Rhodocyclales S CoA-binding protein - - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 SJTD3_k127_942758_3 215803.DB30_3585 8.92e-74 266.0 COG2866@1|root,COG2866@2|Bacteria,1PFUZ@1224|Proteobacteria,43AHH@68525|delta/epsilon subdivisions,2X5XP@28221|Deltaproteobacteria,2YYQC@29|Myxococcales 28221|Deltaproteobacteria E Zn_pept - - - - - - - - - - - - Peptidase_M14 SJTD3_k127_943140_1 211165.AJLN01000148_gene2383 2.951e-93 312.0 COG2303@1|root,COG2303@2|Bacteria,1G5DG@1117|Cyanobacteria,1JJC1@1189|Stigonemataceae 1117|Cyanobacteria E GMC oxidoreductase - - 1.1.3.6 ko:K03333 ko00984,ko01120,map00984,map01120 - R01459 RC00146 ko00000,ko00001,ko01000 - - - GMC_oxred_C,GMC_oxred_N SJTD3_k127_943140_0 1254432.SCE1572_18575 1.24e-105 355.0 COG2267@1|root,COG2303@1|root,COG2267@2|Bacteria,COG2303@2|Bacteria,1QQ8F@1224|Proteobacteria,42PWF@68525|delta/epsilon subdivisions,2WKVA@28221|Deltaproteobacteria,2YYIQ@29|Myxococcales 28221|Deltaproteobacteria E GMC oxidoreductase choD - 1.1.3.6 ko:K03333 ko00984,ko01120,map00984,map01120 - R01459 RC00146 ko00000,ko00001,ko01000 - - - GMC_oxred_C,GMC_oxred_N SJTD3_k127_955251_0 861299.J421_6152 3.007e-243 781.0 COG3459@1|root,COG3459@2|Bacteria,1ZTGS@142182|Gemmatimonadetes 142182|Gemmatimonadetes G Glycosyl hydrolase 36 superfamily, catalytic domain - - - ko:K13688 - - - - ko00000,ko01000,ko01003 - GH94,GT84 - Glyco_hydro_36,Glyco_transf_36,Glycoamylase SJTD3_k127_972726_2 479434.Sthe_2278 5.1e-07 59.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi SJTD3_k127_972726_1 525904.Tter_0789 1.355e-73 256.0 COG0745@1|root,COG2199@1|root,COG0745@2|Bacteria,COG2199@2|Bacteria,2NS3Z@2323|unclassified Bacteria 2|Bacteria T Diguanylate cyclase, GGDEF domain - - - - - - - - - - - - GGDEF,Response_reg SJTD3_k127_972726_0 479434.Sthe_1115 4.97e-174 558.0 COG2204@1|root,COG2204@2|Bacteria,2G5ZP@200795|Chloroflexi 200795|Chloroflexi T Two component, sigma54 specific, transcriptional regulator, Fis family - - - - - - - - - - - - HTH_8,Response_reg,Sigma54_activat SJTD3_k127_984719_0 383372.Rcas_0318 1.181e-118 387.0 COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2G5TN@200795|Chloroflexi,376KE@32061|Chloroflexia 32061|Chloroflexia HP PFAM UBA THIF-type NAD FAD binding protein - - 2.7.7.80,2.8.1.11 ko:K21029,ko:K21147 ko04122,map04122 - R07459,R07461 RC00043 ko00000,ko00001,ko01000 - - - Rhodanese,ThiF SJTD3_k127_984719_1 1298863.AUEP01000009_gene133 1.047e-57 209.0 2AWU5@1|root,31NR9@2|Bacteria,2IQ6J@201174|Actinobacteria 201174|Actinobacteria S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 SJTD3_k127_985467_2 311424.DhcVS_111 2.899e-10 61.0 COG0243@1|root,COG0243@2|Bacteria,2G7RG@200795|Chloroflexi,34D80@301297|Dehalococcoidia 301297|Dehalococcoidia C Molybdopterin oxidoreductase Fe4S4 domain - - - - - - - - - - - - Molybdop_Fe4S4,Molybdopterin,Molydop_binding SJTD3_k127_985467_1 546414.Deide_13360 8.071e-116 378.0 COG1028@1|root,COG1028@2|Bacteria,1WKYF@1297|Deinococcus-Thermus 1297|Deinococcus-Thermus IQ PFAM short chain dehydrogenase - - - - - - - - - - - - adh_short_C2 SJTD3_k127_985467_0 765420.OSCT_1013 1.132e-156 520.0 COG1501@1|root,COG1501@2|Bacteria,2G5TX@200795|Chloroflexi 200795|Chloroflexi G Belongs to the glycosyl hydrolase 31 family - - 3.2.1.20 ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00028,R00801,R00802,R06087,R06088 RC00028,RC00049,RC00077 ko00000,ko00001,ko01000 - GH31 - DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31 SJTD3_k127_991020_0 1128421.JAGA01000004_gene2670 1.298e-51 190.0 COG0346@1|root,COG0346@2|Bacteria 2|Bacteria E lactoylglutathione lyase activity - - 5.1.99.1 ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 M00373,M00375,M00376,M00741 R02765,R09979 RC00780,RC02739 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase SJTD3_k127_991020_1 479434.Sthe_0370 3.273e-48 177.0 2DW90@1|root,33Z49@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1706) - - - - - - - - - - - - - SJTD3_k127_991020_2 1121377.KB906417_gene3855 1.785e-18 100.0 2FA15@1|root,342A8@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - SJTD3_k127_995200_0 485913.Krac_3019 7.13e-168 547.0 COG1132@1|root,COG1132@2|Bacteria 2|Bacteria V (ABC) transporter - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SJTD3_k127_995200_1 485913.Krac_3018 8.047e-138 459.0 COG1132@1|root,COG1132@2|Bacteria,2G86M@200795|Chloroflexi 2|Bacteria P COGs COG1132 ABC-type multidrug transport system ATPase and permease components - - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran SJTD3_k127_995200_2 525904.Tter_2132 2.254e-54 192.0 COG1486@1|root,COG1486@2|Bacteria,2NPAR@2323|unclassified Bacteria 2|Bacteria G Family 4 glycosyl hydrolase - - 3.2.1.22,3.2.1.86 ko:K01222,ko:K07406 ko00010,ko00052,ko00500,ko00561,ko00600,ko00603,map00010,map00052,map00500,map00561,map00600,map00603 - R00839,R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05133,R05134,R05549,R05961,R06091 RC00049,RC00059,RC00171,RC00451,RC00714 ko00000,ko00001,ko01000 - GT4 - Glyco_hydro_4,Glyco_hydro_4C SJTD3_k127_995852_1 1123290.AUDQ01000022_gene745 9.701e-09 68.0 COG0791@1|root,COG0791@2|Bacteria,1V9FW@1239|Firmicutes,4HISN@91061|Bacilli,26FSP@186818|Planococcaceae 91061|Bacilli M S-layer homology domain - - - - - - - - - - - - SLH SJTD3_k127_995852_0 926550.CLDAP_05570 5.353e-108 360.0 COG1921@1|root,COG1921@2|Bacteria,2G5VV@200795|Chloroflexi 200795|Chloroflexi H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis selA - 2.9.1.1 ko:K01042 ko00450,ko00970,map00450,map00970 - R08219 RC01246 ko00000,ko00001,ko01000 - - - Se-cys_synth_N,SelA ## 3405 queries scanned ## Total time (seconds): 341.25890493392944 ## Rate: 9.98 q/s